{"pmid": "20979436", "title": "Localisation of the central sulcus region in glioma patients with three-dimensional fluid-attenuated inversion recovery and volume rendering: comparison with functional and conventional magnetic resonance.", "content": "Localisation of the central sulcus region in glioma patients with three-dimensional fluid-attenuated inversion recovery and volume rendering: comparison with functional and conventional magnetic resonance. Volume rendering (VR) of three-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) magnetic resonance (MR) images shows regional intensity differences, reflecting the central sulcus (CS) region and occipital cortex. The purpose of this study was to determine whether 3D FLAIR with VR could be used as an alternative method to localise the CS region in comparison with functional and conventional MR-imaging in patients with perirolandic glioma. Eleven patients with intracranial gliomas were studied with single-slab 3D FLAIR including VR and conventional T1-weighted imaging. In all patients, preoperative functional magnetic resonance imaging (fMRI) was performed with a motor paradigm of the hand. The hypo-intense central gyri on 3D FLAIR with VR were interpreted as the CS area. Localisation of the motor hand knob on anatomical images and fMRI results were used for identification of the primary motor cortex. Anatomical localisation of the motor hand knob on T1-weighted images was possible in 91% of both hemispheres. In 73% of the affected hemispheres (AH) and 91% of the unaffected hemispheres (UH) the hand knob and CS region could be identified on 3D FLAIR axial and VR images, respectively. With one exception, fMRI activation confirmed the CS region as observed with 3D FLAIR with VR. Volume rendering of 3D FLAIR MR images shows central hypo-intensities frequently corresponding with the CS region. Two-dimensional localisation of the CS region on conventional T1-weighted images and fMRI seems favourable compared to 3D FLAIR. However, in selected cases, especially where fMRI is not possible or feasible, volume rendering with 3D FLAIR may enhance the 3D visualisation of gliomas in relation to the CS region which can be used as an alternative method in the presurgical structural and functional evaluation of neurosurgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979436"}
{"pmid": "20979435", "title": "Novel strategies in brachial plexus repair after traumatic avulsion.", "content": "Novel strategies in brachial plexus repair after traumatic avulsion. Clinical trials in spinal cord injury (SCI) can be affected by many confounding variables including spontaneous recovery, variation in the lesion type and extend. However, the clinical need and the paucity of effective therapies has spawned a large number of animal studies and clinical trials for SCI. In this review, we suggest that brachial plexus avulsion injury, a longitudinal spinal cord lesion, is a simpler model to test methods of spinal cord repair. We explore reconstructive techniques currently explored for the repair of brachial plexus avulsion and focus on the use of olfactory ensheathing cell transplantation as an adjunct treatment in brachial plexus repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979435"}
{"pmid": "20979438", "title": "Temporary bilateral external carotid artery clamping to reduce blood loss during removal of calvarial meningioma: a technical note.", "content": "Temporary bilateral external carotid artery clamping to reduce blood loss during removal of calvarial meningioma: a technical note. Large calvarial lesions may bleed extensively during their removal. The main vascular supply to such lesions is from branches of the external carotid arteries (ECAs). Bilateral ECA embolisation has been described to reduce the vascularity, and therefore blood loss of such lesions during their surgical removal, but it is expensive and not easily available in developing countries. In addition, it is associated with significant morbidity. A case of a large calvarial meningioma, extending across the midline is presented in which both external carotids were temporarily clamped to reduce blood loss. Blood loss was low and the complications of permanent occlusion of the arteries avoided. This technique can be used for vascular calvarial lesions extending across the midline where embolisation is not feasible or has failed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979438"}
{"pmid": "20979439", "title": "Stem cells in the adult human brain.", "content": "Stem cells in the adult human brain. The rapidly advancing field of stem cell research holds great promise for regenerative medicine. Regenerating brain tissue, while technically the most challenging application of stem cell biology, is also likely to reap the most reward for patients. Here, we review the current state of stem cell research in the field of human neuroscience and highlight aspects that will be of relevance to neurosurgeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979439"}
{"pmid": "20979440", "title": "The presigmoid approach for removal of tumours causing ventral compression of the brainstem. Surgical results and postoperative quality of life.", "content": "The presigmoid approach for removal of tumours causing ventral compression of the brainstem. Surgical results and postoperative quality of life. To assess surgical results and quality of life after removal of tumours causing ventral compression of the brainstem using the presigmoid or combined presigmoid/retrosigmoid approaches. A review of all our patients operated on with removal of tumours causing ventral compression of the brainstem in whom either the presigmoid or combined presigmoid/retrosigmoid approaches were used. Post-operative quality of life was assessed using the SF-36 questionnaire. A total of 12 consecutive patients were included. A favourable complication profile was found. Cerebrospinal fluid leakage and secondary hydrocephalus were the most frequent complications. Post-operative scores from Karnofsky Performance Scale and ECOG after median 24 months were median 85 and 1, respectively, representing ability to carry on daily activities. Nevertheless, quality of life as assessed subjectively by SF-36 showed significantly reduced values as compared with normative values from Norwegian population. We found favourable surgical results when using the presigmoid approach alone or combined with the retrosigmoid route for large-sized extrinsic tumours causing ventral compression of the brainstem, both regarding complication profile, degree of tumour removal and functional outcome. However, impact of disease and surgery on quality of life appears to be more significant when assessed subjectively by the patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979440"}
{"pmid": "20979441", "title": "Bone marrow as a source of hematopoietic stem cells for human gene therapy of β-thalassemia.", "content": "Bone marrow as a source of hematopoietic stem cells for human gene therapy of β-thalassemia. β-Thalassemia is a severe inherited anemia caused by insufficient production of β-globin chains. Allogeneic hematopoietic stem cell (HSC) transplantation is currently the only cure, and is limited by donor availability and regimen-related toxicity and mortality. Gene therapy is a promising therapeutic tool for all thalassemic patients lacking a compatible donor and potentially provides transfusion independence in the absence of transplant-related complications, such as graft rejection and graft-versus-host disease. The issue of HSC procurement is critical in this setting because of the specific features of thalassemic syndromes, which include bone marrow (BM) expansion, ineffective erythropoiesis, and splenomegaly. Little is known about the efficiency of CD34(+) cell yield from steady-state BM harvests from thalassemic patients. We have collected data on safety and cell yield from 20 pediatric patients with β-thalassemia who underwent autologous BM harvest before allogeneic HSC transplantation, and from 49 age-matched sibling donors who also underwent BM harvest. The procedure was safe, as no significant adverse events occurred. In terms of cell yield, no difference was found between patients and normal donors in the number of CD34(+) cells and total nucleated cells harvested. Most importantly, no difference was found in the proportion of myeloid and erythroid progenitors, suggesting a similar repopulating capacity. On the basis of these results, we conclude that steady-state BM can be used as a safe and efficient source of HSC for gene therapy of β-thalassemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979441"}
{"pmid": "20979437", "title": "Recurrence of benign meningiomas: predictive value of proliferative index, BCL2, p53, hormonal receptors and HER2 expression.", "content": "Recurrence of benign meningiomas: predictive value of proliferative index, BCL2, p53, hormonal receptors and HER2 expression. The biological behaviour of meningiomas and the risk of recurrence in individual cases cannot be predicted by using conventional histological criteria alone. A number of histologically benign meningiomas may recur, even after gross complete surgical removal. A retrospective immunohistochemical and statistical analysis of 60 patients with benign intracranial meningiomas (that have been grossly totally resected) was undertaken to determine the correlation of clinicopathological characteristics and expression of biological markers (proliferation index (PI) assessed by Ki67, hormonal receptors, p53, BCL2 and HER2, estrogen receptors, ER and progesterone receptors, PR) with prediction of recurrence. HER2 expression showed a significant inverse correlation with PR and a significant direct correlation with PI. PR-negative and HER2-positive cases showed a statistically significant higher mean PI than PR positive and HER2-negative cases. Univariate analysis showed that recurrence was significantly associated with male gender, cranial base location, the presence of bone and soft tissue invasion, some atypical histological features, higher PI, negative PR expression, and positive p53, BCL2 and HER2 expression. Multivariate analysis showed that the presence of bone and soft tissue invasion and/or the expression of p53 proved to be independent predictors of tumour recurrence. The presence of some atypical histological features and high PI were significant predictors of tumor recurrence, however, they were statistically excluded to avoid multicolinearity. Risk stratification based on histomorphology alone remains problematic. We conclude that soft tissue and bone invasion, some atypical histological features, p53 expression and high PI identify meningiomas with benign histological features but unfavourable clinical outcome. We suggest that those patients should be followed more closely for evidence of recurrent tumour or may be treated more aggressively at the time of diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979437"}
{"pmid": "20979443", "title": "E13.5 retinal progenitors induce mouse bone marrow mesenchymal stromal cells to differentiate into retinal progenitor-like cells.", "content": "E13.5 retinal progenitors induce mouse bone marrow mesenchymal stromal cells to differentiate into retinal progenitor-like cells. Retinal progenitor cells (RPC) are an excellent resource for retinal replacement therapy but usually unavailable. We attempted to induce bone marrow mesenchymal stromal cells (BMSC) into RPC. BMSC and embryonic day 13.5 (E13.5) RPC derived from wild-type or enhanced green fluorescence protein (EGFP) transgenic (Egfp(+/+)) mice were co-cultured in a transwell or re-aggregation system. Gene and protein expressions were investigated by reverse transcription-polymerase chain reaction (PCR) and immunofluorescence, respectively. Spontaneous cell fusion was evaluated by Chloromethylbenzamido derivative of 1,1'- dioctadecyl-3,3,3',3' - tetramethylindocarbocyanine perchlorate (CM-DiI) labeling together with EGFP tracing. BMSC from both wild-type and Egfp(+/+) mice displayed similar spindle shapes. The undifferentiated BMSC already expressed immature neural markers but did not express Nfl, Gfap or the retina-related genes Pax6, Math5 and Brn3b. When co-cultured with E13.5 RPC in the transwell system, BMSC displayed transient expression of early retinal development genes, including Pax6, Math5 and Brn3b at 3 days, as well as long-term expression of Nfl (up to 21 days). No expression of the late photoreceptor gene rhodopsin could be detected at any time. In re-aggregation co-culture, E13.5 RPC induced EGFP-positive BMSC to express not only the early retinal development genes but also the late gene rhodopsin. Furthermore, a small fraction of BMSC could be induced to express the synaptophysin protein. Re-aggregation co-culture of CM-DiI-labeled BMSC and EGFP-positive E13.5 RPC displayed minimal co-localization of the two fluorescence signals. E13.5 RPC are capable of inducing BMSC towards an RPC fate. The differentiation is independent of cell fusion. Cytokines and cell-cell interactions exert this induction effect, but they have different functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979443"}
{"pmid": "20979442", "title": "Bioresponsive hyperbranched polymers for siRNA and miRNA delivery.", "content": "Bioresponsive hyperbranched polymers for siRNA and miRNA delivery. This work presents the novel use of reducible hyperbranched (rHB) polymers for delivery of RNA interference (RNAi) therapeutics. Cationic poly(amido amine) hyperbranched polymers that contain different contents of reducible disulfide to nonreducible linkages (0%, 17%, 25%, and 50%) were used to form interpolyelectrolyte polyplexes with siRNA and precursor miRNA (pre-miRNA). Atomic force microscopy (AFM) revealed rHB complexes of ∼100 nm in size, which exhibited redox-activated disassembly in the presence of dithiothreitol (DTT). The complexes were avidly internalized and showed no cellular toxicity in an endogenous enhanced green fluorescence protein (EGFP) expressing H1299 human lung cancer cell line. The highest specific EGFP gene silencing (∼75%) was achieved with rHB (17%)/siRNA complexes at a weight-to-weight (w/w) ratio of 40 that correlated with the ability for this polymer to successfully transfect pre-miRNA. Evaluation of temporal silencing levels over 72 h revealed incremental knockdown that reached a maximum at 72 h for the rHB (50%) complexes, in contrast to maximum knockdown at 24 h that remained relatively consistent, thereafter, for the rHB (17%), rHB (25%), and non-rHB complexes. The role of particle disassembly for intracellular targeting and modulation of gene silencing addressed in this work are important considerations in the development of this and other next-generation delivery systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979442"}
{"pmid": "20979445", "title": "3D and 4D sonography and magnetic resonance in the assessment of normal and abnormal CNS development: alternative or complementary.", "content": "3D and 4D sonography and magnetic resonance in the assessment of normal and abnormal CNS development: alternative or complementary. Advanced transvaginal neurosonography has revealed normal and abnormal intracranial morphology. Transvaginal three-dimensional (3D) sonography demonstrates bony structure, multiplanar analysis of inside detailed morphology, tomographic ultrasound imaging in any cutting sections, 3D sonoangiography and volume calculation of ventricles and/or intracranial lesions. Longitudinal assessment of normal and abnormal central nervous system (CNS) development is done by serial scanning. However, the transvaginal high-frequency approach has several limitations due to lack of penetration and cranial bone ossification with advanced gestational age. Magnetic resonance neuroimaging enabled observation of the whole intracranial cavity, brainstem and cortical gyral/sulcal development. On the other hand, neuro-sonography has advantages in detecting intracranial calcification, vascular abnormalities, intratumoral vascularity and bone dysplasia. Moreover, 3D ultrasound demonstrates extra CNS abnormalities, strongly associated with CNS abnormalities. Any less-invasive modalities can be used for a CNS anomaly screening scan and ultrasound is no doubt the first choice. Once CNS abnormality is suspected, it is suggested to use the different technologies according to what is looked for in each abnormal CNS case. Of course, MR and 3D ultrasound imaging should be complementary as well as alternative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979445"}
{"pmid": "20979444", "title": "Isolation of Cryptococcus magnus and Cryptococcus chernovii from nasal cavities of pediatric patients with acute lymphoblastic leukemia.", "content": "Isolation of Cryptococcus magnus and Cryptococcus chernovii from nasal cavities of pediatric patients with acute lymphoblastic leukemia. We report the isolation of Cryptococcus magnus and Cryptococcus chernovii in cultures inoculated with nasal specimens of pediatric cancer patients with acute lymphoblastic leukemia. The phenotypic characteristics of the isolates are described and their identity confirmed by sequencing of rDNA. Both species were resistant to caspofungin, anidulafungin, 5-flucytosine and itraconazole, but susceptible to amphotericin B, posaconazole and voriconazole. To the best of our knowledge, the isolation of these two species from nasal cavities has not been reported previously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979444"}
{"pmid": "20979447", "title": "Predicting survival of periviable fetuses using NICHD fetal heart rate categories.", "content": "Predicting survival of periviable fetuses using NICHD fetal heart rate categories. To evaluate whether National Institute of Child Health and Human Health and Development (NICHD) fetal heart rate categories were predictive of neonatal survival in periviable pregnancies. We reviewed the charts of 57 infants delivered at 23 and 24 weeks' gestation. Fetal heart rate tracings were evaluated following the NICHD 2008 criteria, using the acceleration height of 10 bpm and duration of 10 s. Multiple logistic regression analyses were performed using survival, fetal morbidities, and cord pH <7.1 as dependent variables. Independent variables included fetal heart rate category, mode of delivery, resuscitation, and histological chorioamnionitis. Outcomes of infants delivered at 23 and 24 weeks were also compared. In 23-week pregnancies, fetal heart rate category 2 was associated with improved short-term survival compared to category 3 (OR 1.3, 95% CI 0.11-15.7). Cesarean delivery and histological chorioamnionitis were not predictive of survival [(OR 0.5, 95% CI 0.04-7.1, and OR 0.4, 95% CI 0.02-6.85), respectively]. Long-term survival for infants born at 23 and 24 weeks was 8% and 56%, respectively. The NICHD fetal heart rate category during labor may be associated with survival for infants born at 23 and 24 weeks of gestation. Cesarean delivery was not associated with improved survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979447"}
{"pmid": "20979446", "title": "Evaluation and clinical application of changes in thyroid hormone and TSH levels in critically ill full-term newborns.", "content": "Evaluation and clinical application of changes in thyroid hormone and TSH levels in critically ill full-term newborns. The term \"euthyroid sick syndrome\" (ESS) has been used to describe a pattern of thyroid hormone changes during the course of critical illness in adult patients without thyroid disease, often associated with reduced thyroid hormone secretion. To describe the thyroid hormone profile in full-term newborns critically ill compared with thyroid hormone profile of healthy infants, and determine if alterations could be related to the severity of the disease and outcome. A cross-sectional, observational, and prospective study of full-term infants admitted to the neonatal intensive care unit (NICU) of the Hospital de Pediatría J.P. Garrahan between July 2007 and April 2008. Serum T3, T4, and thyroid stimulating hormone (TSH) levels were measured at admission and severity of the disease was evaluated through SNAP, lactic acid, respiratory assistance and number of organs affected. Sick newborns showed significantly lower T3 and T4 levels compared with healthy infants [T3: -0.97 μg/dL (95% CI -0.89, -1.13) and T4: -4.37 μg/dL (95% CI -2.95, -5.78)]. Only 29 out of 94 (31%) infants presented a normal profile; 37 (39%) infants showed isolated low T3 levels, 20 (21%) infants had low T3 and T4 levels and eight (9%) infants had low TSH, T3, and T4. Of this latter group, five of eight (62%) children died suggesting a significantly higher risk of death for patients with low T3 associated with low T4 and TSH [Risk ratio (RR) 10.75 95% CI 3.93, 29]. Full-term sick newborns frequently have lower thyroid hormone levels than healthy ones. These observed thyroid hormones changes might be related to the underlying disease and could be used as a prognostic marker of the severity and fatal outcome of the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979446"}
{"pmid": "20979448", "title": "Epidemiology of congenital syphilis in a South Bronx population: a follow-up study.", "content": "Epidemiology of congenital syphilis in a South Bronx population: a follow-up study. Despite widespread prenatal serological screening, the Centers for Disease Control recently reported that from 2005 to 2008, congenital syphilis increased by 23%, many being born to black women in the southern United States. We collected data on the epidemiology of this condition in our institution for the past 18 years (January 1, 1991-December 31, 2008). There has been a marked decrease in the incidence of active infection since the 1990s. Through the 18 years period reviewed, only 21 cases of active neonatal infection were documented among 699 babies who had a positive rapid plasma reagin test. Of these 21 cases, only one was symptomatic. As compared to previous studies, poor prenatal care has still the greatest correlation with active infection. This study might contribute towards the reinforcement of current programs and the formulation of newer strategies towards control and elimination of this condition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979448"}
{"pmid": "20979449", "title": "Cell and molecular physiology diversity of channels, carriers, and pumps.", "content": "Cell and molecular physiology diversity of channels, carriers, and pumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979449"}
{"pmid": "20979451", "title": "Transport and metabolism of (±)-praeruptorin A in Caco-2 cell monolayers.", "content": "Transport and metabolism of (±)-praeruptorin A in Caco-2 cell monolayers. (±)-Praeruptorin A (dl-PA) is one of the main pyranocoumarins of Peucedani Radix and the chemical marker for quality control of the herb in China. This study investigated the transport and metabolism of dl-PA, for the first time, in Caco-2 cell monolayers. PA enantiomers of dl-PA in the transport study were simultaneously determined using a simple and rapid enantio-selective high performance liquid chromatography-UV method. Both dextrorotatory (d-PA) and levorotatory (l-PA) enantiomers traversed Caco-2 monolayer rapidly in both directions (absorptive P(app): 2.01-3.03 × 10(-5) cm/s; secretory P(app): 1.58-1.96 ×10(-5) cm/s) mainly via passive diffusion. Higher transport rates of dPA were observed in both directions. PA enantiomers were incompletely recovered after the transport study. Nonspecific binding to the Transwell inserts, irreversible binding to cellular components and metabolism within the cells accounted for the loss. dl-PA was partially hydrolyzed in Caco-2 monolayers and yielded two stereoisomers via removal of the acetyl group from C-4' position. Both phenylmethylsulphonyl fluoride (a nonspecific esterase inhibitor) and bis(p-nitrophenyl) phosphate sodium salt (a specific inhibitor of carboxylesterases) completely abolished dl-PA hydrolysis. In summary, PA enantiomers were rapidly transported across Caco-2 cells and partially hydrolyzed by carboxylesterases during permeation. These findings provide mechanistic understanding of in vivo pharmacokinetic properties of dl-PA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979451"}
{"pmid": "20979452", "title": "Amniotic mesenchymal stem cells enhance normal fetal wound healing.", "content": "Amniotic mesenchymal stem cells enhance normal fetal wound healing. Fetal wound healing involves minimal inflammation and limited scarring. Its mechanisms, which remain to be fully elucidated, hold valuable clues for wound healing modulation and the development of regenerative strategies. We sought to determine whether fetal wound healing includes a hitherto unrecognized cellular component. Two sets of fetal lambs underwent consecutive experiments at midgestation. First, fetuses received an intra-amniotic infusion of labeled autologous amniotic mesenchymal stem cells (aMSCs), in parallel to different surgical manipulations. Subsequently, fetuses underwent creation of 2 symmetrical, size-matched skin wounds, both encased by a titanium chamber. One of the chambers was left open and the other covered with a semipermeable membrane that allowed for passage of water and all molecules, but not any cells. Survivors from both experiments had their wounds analyzed at different time points before term. Labeled aMSCs were documented in all concurrent surgical wounds. Covered wounds showed a significantly slower healing rate than open wounds. Paired comparisons indicated significantly lower elastin levels in covered wounds at the mid time points, with no significant differences in collagen levels. No significant changes in hyaluronic acid levels were detected between the wound types. Immunohistochemistry for substance P was positive in both open and covered wounds. We conclude that fetal wound healing encompasses an autologous yet exogenous cellular component in naturally occurring aMSCs. Although seemingly not absolutely essential to the healing process, amniotic cells expedite wound closure and enhance its extracellular matrix profile. Further scrutiny into translational implications of this finding is warranted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979452"}
{"pmid": "20979450", "title": "Pregnane X receptor-mediated induction of Cyp3a by black cohosh.", "content": "Pregnane X receptor-mediated induction of Cyp3a by black cohosh. Black cohosh (BC) has been widely applied for the treatment of menopausal symptoms. However, increasing concerns about herb-drug interactions demand the need for studies on the influence of BC on cytochrome 450. Cyp3a11 in liver was induced by 7-fold in wild-type mice treated with 500 mg/kg black cohosh for 28 days compared with the control group as assessed by quantitative real-time PCR; no difference was found in small intestine and kidney, suggesting that up-regulation of Cyp3a11 by black cohosh was liver-specific. Western blot, activity assays, and pharmacokinetic analyses established dose- and time-dependent induction of Cyp3a11. To determine the mechanism of Cyp3a11 induction, including the role of pregnane X receptor (PXR) in vivo and in vitro, respectively, in Pxr-null, PXR-humanized, and double transgenic CYP3A4/hPXR mice, cell-based luciferase assays were employed revealing that mouse PXR played a direct role in the induction of Cyp3a11; human PXR was not activated by black cohosh. Overall, these findings demonstrate that induction of Cyp3a11 is liver-specific and involved only mouse PXR, not the human counterpart. Thus, the incidence of herb-drug interaction in patients administered black cohosh may not be mediated by human PXR and CYP3A4.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979450"}
{"pmid": "20979453", "title": "Both CD31(+) and CD31⁻ naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy.", "content": "Both CD31(+) and CD31⁻ naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy. Naive T cell recovery is critical for successful immune reconstitution after antiretroviral therapy (ART), but the relative contribution of CD31(+) and CD31⁻ naive T cells to immune reconstitution and viral persistence is unknown. In a cross-sectional (n = 94) and longitudinal (n = 10) study of human immunodeficiency virus (HIV)-infected patients before and after ART, we examined the ratio of CD31(+) to CD31⁻ naive CD4(+) T cells. In the longitudinal cohort we then quantified the concentration of HIV-1 DNA in each cell subset and performed single-genome amplification of virus from memory and naive T cells. Patients receiving ART had a higher proportion of CD31(+) CD4(+) T cells than HIV-1-infected individuals naive to ART and uninfected control subjects (P < .001 and .007, respectively). After 24 months of ART, the proportion of CD31(+) naive CD4(+) T cells did not change, the concentration of HIV-1 DNA in memory CD4(+) T cells significantly decreased over time (P < .001), and there was no change in the concentration of HIV-1 DNA in CD31(+) or CD31⁻ naive CD4(+) T cells (P = .751 and .251, respectively). Single-genome amplification showed no evidence of virus compartmentalization in memory and naive T cell subsets before or after ART. After ART, both CD31(+) and CD31⁻ naive CD4(+) T cells expand, and both subsets represent a stable, persistent reservoir of HIV-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979453"}
{"pmid": "20979454", "title": "Inactivated seasonal influenza vaccines increase serum antibodies to the neuraminidase of pandemic influenza A(H1N1) 2009 virus in an age-dependent manner.", "content": "Inactivated seasonal influenza vaccines increase serum antibodies to the neuraminidase of pandemic influenza A(H1N1) 2009 virus in an age-dependent manner. Levels of preexisting antibodies to the hemagglutinin of pandemic influenza A(H1N1) 2009 (hereafter pandemic H1N1) virus positively correlate with age. The impact of contemporary seasonal influenza vaccines on establishing immunity to other pandemic H1N1 proteins is unknown. We measured serum antibodies to the neuraminidase (NA) of pandemic H1N1 in adults prior to and after vaccination with seasonal trivalent inactivated influenza vaccines. Serum antibodies to pandemic H1N1 NA were observed in all age groups; however, vaccination elevated levels of pandemic H1N1 NA antibodies predominately in elderly individuals (age, ⩾60 years). Therefore, contemporary seasonal vaccines likely contribute to reduction of pandemic H1N1-associated disease in older individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979454"}
{"pmid": "20979457", "title": "A norovirus vaccine on the horizon?", "content": "A norovirus vaccine on the horizon?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979457"}
{"pmid": "20979455", "title": "Adjuvanted intranasal Norwalk virus-like particle vaccine elicits antibodies and antibody-secreting cells that express homing receptors for mucosal and peripheral lymphoid tissues.", "content": "Adjuvanted intranasal Norwalk virus-like particle vaccine elicits antibodies and antibody-secreting cells that express homing receptors for mucosal and peripheral lymphoid tissues. Noroviruses cause significant morbidity and mortality from acute gastroenteritis in all age groups worldwide. We conducted 2 phase 1 double-blind, controlled studies of a virus-like particle (VLP) vaccine derived from norovirus GI.1 genotype adjuvanted with monophosphoryl lipid A (MPL) and the mucoadherent chitosan. Healthy subjects 18-49 years of age were randomized to 2 doses of intranasal Norwalk VLP vaccine or controls 21 days apart. Study 1 evaluated 5-, 15-, and 50-μg dosages of Norwalk antigen, and study 2 evaluated 50- and 100-μg dosages. Volunteers recorded symptoms for 7 days after dosing, and safety was followed up for 180 days. Blood samples were collected for serological profile, antibody secreting cells (ASCs), and analysis of ASC homing receptors. The most common symptoms were nasal stuffiness, discharge, and sneezing. No vaccine-related serious adverse events occurred. Norwalk VLP-specific immunoglobulin G and immunoglobulin A antibodies increased 4.8- and 9.1-fold, respectively, for the 100-μg dosage level. All subjects tested who received the 50- or 100-μg vaccine dose developed immunoglobulin A ASCs. These cells expressed molecules associated with homing to mucosal and peripheral lymphoid tissues. The intranasal monovalent adjuvanted Norwalk VLP vaccine was well tolerated and highly immunogenic and is a candidate for additional study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979455"}
{"pmid": "20979456", "title": "Staphylococcal superantigens cause lethal pulmonary disease in rabbits.", "content": "Staphylococcal superantigens cause lethal pulmonary disease in rabbits. The Centers for Disease Control and Prevention (CDC) and others reported that methicillin-resistant S. aureus (MRSA) are significant causes of serious human infections, including pulmonary illnesses. We investigated the role played by superantigens in lung-associated lethal illness in rabbits. A rabbit model was established to investigate the potential role played by superantigens, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC), and toxic shock syndrome toxin-1 (TSST-1). Rabbits received intrabronchial community-associated (CA) MRSA strains USA200 (TSST-1(+)), MW2 (SEC(+)), c99-529 (SEB(+)), or purified superantigens. Some rabbits were preimmunized against superantigens or treated with soluble high-affinity T cell receptors (Vβ-TCR) to neutralize SEB and then challenged intrabronchially with CA-MRSA or superantigens. Rabbits challenged with CA-MRSA or superantigens developed fatal, pulmonary illnesses. Animals preimmunized against purified superantigens, or treated passively with Vβ-TCRs and then challenged with CA-MRSA or superantigens, survived. Lung histological analysis indicated that nonimmune animals developed lesions consistent with necrotizing pneumonia after challenge with CA-MRSA or purified superantigens. Superantigen-immune animals or animals treated with soluble Vβ-TCRs did not develop pulmonary lesions. Superantigens contribute to lethal pulmonary illnesses due to CA-MRSA; preexisting immunity to superantigens prevents lethality. Administration of high-affinity Vβ-TCR with specificity for SEB to nonimmune animals protects from lethal pulmonary illness resulting from SEB(+) CA-MRSA and SEB.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979456"}
{"pmid": "20979458", "title": "Immune responses to Helicobacter pylori infection in Bangladeshi children during their first two years of life and the association between maternal antibodies and onset of infection.", "content": "Immune responses to Helicobacter pylori infection in Bangladeshi children during their first two years of life and the association between maternal antibodies and onset of infection. A birth cohort of 238 children in Bangladesh was monitored during the initial 2 years of life to analyze immune responses against Helicobacter pylori in relation to infection and spontaneous eradication and to evaluate a possible association between maternal antibodies and protection against early onset of infection. H. pylori infection was determined by a stool antigen test and serologic testing. Immune responses were analyzed in depth in 50 children. Of the stool antigen-positive children, 90% developed ≥4-fold increased antibody levels against H. pylori in serum immunoglobulin (Ig) A, 73% developed increases in serum IgG levels, and 81% developed increases in stool IgA/total IgA levels after, as compared with before, the onset of infection. Good agreement between different immune responses was observed after 6 months of age. Before that time, transplacentally derived IgG and breast milk IgA antibodies interfered with the children's serum IgG and stool IgA responses. Children infected during the first year of life had significantly lower preinfection serum IgG titers than those infected during the second year of life. Infants infected during the first month of life were fed breast milk that contained levels of H. pylori IgA antibodies that were significantly lower than the levels in breast milk fed to infants infected at 6 months of age. Children who experienced spontaneous eradication of infection developed significantly higher serum IgA antibody levels after infection than did children with continuous infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979458"}
{"pmid": "20979460", "title": "Acupressure as a non-pharmacological intervention for traumatic brain injury (TBI).", "content": "Acupressure as a non-pharmacological intervention for traumatic brain injury (TBI). Acupressure is a complementary and alternative medicine (CAM) treatment using fingertips to stimulate acupoints on the skin. Although suggested to improve cognitive function, acupressure has not been previously investigated with a controlled design in traumatic brain injury (TBI) survivors, who could particularly benefit from a non-pharmacological intervention for cognitive impairment. A randomized, placebo-controlled, single-blind design assessed the effects of acupressure (eight treatments over 4 weeks) on cognitive impairment and state of being following TBI, including assessment of event-related potentials (ERPs) during Stroop and auditory oddball tasks. It was hypothesized that active acupressure treatments would confer greater cognitive improvement than placebo treatments, perhaps because of enhanced relaxation response induction and resulting stress reduction. Significant treatment effects were found comparing pre- to post-treatment change between groups. During the Stroop task, the active-treatment group showed greater reduction in both P300 latency (p = 0.010, partial η² = 0.26) and amplitude (p = 0.011, partial η² = 0.26), as well as a reduced Stroop effect on accuracy (p = 0.008, partial η² = 0.21) than did the placebo group. Additionally, the active-treatment group improved more than did the placebo group on the digit span test (p = 0.043, Cohen's d = 0.68). Together, these results suggest an enhancement in working memory function associated with active treatments. Because acupressure emphasizes self-care and can be taught to novice individuals, it warrants further study as an adjunct treatment for TBI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979460"}
{"pmid": "20979459", "title": "Circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults.", "content": "Circulating antibody-secreting cells during acute respiratory syncytial virus infection in adults. The specificity and duration of circulating human antibody-secreting cells (ASCs) after vaccination have been well described, but characteristics of ASCs during acute respiratory infections have not been well studied. Circulating antigen-specific ASCs were measured at 3 time points (enrollment, days 10-16, and days 22-45) in 40 adults during respiratory syncytial virus (RSV) infection. Of the 40 patients, 36 (90%) had detectable circulating RSV F protein-specific ASCs within 11 days after illness onset. The magnitude of the RSV-specific ASCs was 1-1500 spots per 10⁶ peripheral blood mononuclear cells (mean frequency [± standard deviation], 200 ± 256 spots per 10⁶ peripheral blood mononuclear cells). ASCs were detected on day 8-16 and day 22-45 after symptom onset in 78% and 48% of subjects, respectively. Subjects shedding virus for >10 days were more likely to have a positive response to ASC enzyme-linked immunospot assay at the late time point than those shedding for ≤10 days (8 of 12 subjects vs 2 of 11 subjects; P = .02). The kinetics of ASC circulation during acute mucosal viral infections was more prolonged than that we had observed after a single intramuscular injection with inactivated influenza vaccine in a study reported elsewhere. The association between the duration of virus shedding and the persistence of detectable viral-specific ASCs suggests that ongoing antigen persistence induces a prolonged temporal pattern of ASC generation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979459"}
{"pmid": "20979461", "title": "Clinical and metabolic effects of drospirenone-estradiol in menopausal women: a prospective study.", "content": "Clinical and metabolic effects of drospirenone-estradiol in menopausal women: a prospective study. To describe the effects of low-dose hormonal replacement therapy (HRT) on quality of life, metabolic parameters and blood pressure in postmenopausal women. Postmenopausal women untreated with HRT or sex steroids in the previous 12 months were randomized to treatment with 17β-estradiol (1 mg/day) plus drospirenone (2 mg/day) (E2+DRSP) or to calcium (controls). Quality of life was evaluated by the Women's Health Questionnaire (WHQ) at baseline and after 6 and 12 weeks of treatment. Anthropometric, metabolic and blood pressure measurements were performed before and after 3 months of treatment. WHQ domain scores for vasomotor and somatic symptoms, anxiety/fears, depressed mood, sexual behavior and sleep problems decreased significantly in the E2+DRSP group relative to both baseline and control values (p < 0.05). Body mass index was unchanged, while waist circumference decreased significantly (p < 0.001) after E2+DRSP treatment. Significant decreases were also observed after E2+DRSP treatment for blood insulin values, insulin resistance (estimated by homeostasis model assessment) and systolic blood pressure (p < 0.001, all). In subjects with systolic blood pressure < 130 mmHg at baseline, no changes in systolic values were registered, while women with baseline high-normal systolic blood pressure (130-139 mmHg) showed significant decreases (p < 0.0069). E2+DRSP did not modify diastolic blood pressure values. In the calcium-treatment group, there were no significant changes in WHQ scores or in anthropometric, metabolic or blood pressure measurements. In postmenopausal women, E2+DRSP administration improves vasomotor symptoms and general aspects of quality of life and may positively influence cardiovascular risk factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979461"}
{"pmid": "20979462", "title": "Factors associated with non-compliance with hormone therapy cessation before screening mammography.", "content": "Factors associated with non-compliance with hormone therapy cessation before screening mammography. To evaluate factors associated with non-compliance with discontinuation of hormone therapy (HT) within a study on the effect of HT cessation on mammography performance. This randomized, controlled trial was conducted at Group Health, a health plan in Washington State, USA. Eligibility included: age 45-80 years; due for screening ('study') mammogram; and prior screening mammogram while using HT. We randomized 1704 women to no cessation (n = 567), 1-month (n = 570), or 2-month cessation (n = 567), and called participants before cessation to review instructions. We collected self-reported data at randomization (baseline) and before the study mammogram, including symptoms and compliance. This analysis includes women randomized to 1-month or 2-month cessation with complete baseline and follow-up questionnaires (n = 883). Most participants were using unopposed estrogen (63.3%) and intended to continue HT (90%); 9.6% were non-compliant with HT cessation. Comparing 2-month vs. 1-month cessation, the age and body mass index (BMI)-adjusted relative risk (RR) for non-compliance was 1.72 (95% confidence interval (CI) 1.12-2.60). Baseline variables associated with non-compliance included: age ≤55 vs. >55 years (RR 2.34; 95% CI 1.34-4.41); BMI < 25 vs. BMI ≥30 kg/m 2 (RR 1.63; 95% CI 1.01-2.63); unopposed estrogen vs. estrogen plus progestin (RR 1.59; 95% CI 1.01-2.51); using HT to manage sleep (RR 1.80; 95% CI 1.20-2.71); severe vs. no night sweats (RR 1.68; 95% CI 1.03-2.74); and night sweats that interfered with sleep (RR 1.78; 95% CI 1.02-3.11). Non-compliance with HT cessation before screening mammogram was associated with younger age, lower BMI, symptom severity and use of unopposed estrogen. Alternatives for menopause symptom management are needed to assist women with HT cessation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979462"}
{"pmid": "20979463", "title": "Health care in the 2010 congressional election.", "content": "Health care in the 2010 congressional election.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979463"}
{"pmid": "20979464", "title": "Writing new rules for insurers--progress on the medical loss ratio.", "content": "Writing new rules for insurers--progress on the medical loss ratio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979464"}
{"pmid": "20979465", "title": "A \"broader regulatory scheme\"--the constitutionality of health care reform.", "content": "A \"broader regulatory scheme\"--the constitutionality of health care reform.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979465"}
{"pmid": "20979466", "title": "Images in clinical medicine. Air in the middle of the abdomen.", "content": "Images in clinical medicine. Air in the middle of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979466"}
{"pmid": "20979467", "title": "Resurrection of a stem-cell funding barrier--Dickey-Wicker in court.", "content": "Resurrection of a stem-cell funding barrier--Dickey-Wicker in court.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979467"}
{"pmid": "20979469", "title": "Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.", "content": "Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. Oncogenic fusion genes consisting of EML4 and anaplastic lymphoma kinase (ALK) are present in a subgroup of non-small-cell lung cancers, representing 2 to 7% of such tumors. We explored the therapeutic efficacy of inhibiting ALK in such tumors in an early-phase clinical trial of crizotinib (PF-02341066), an orally available small-molecule inhibitor of the ALK tyrosine kinase. After screening tumor samples from approximately 1500 patients with non-small-cell lung cancer for the presence of ALK rearrangements, we identified 82 patients with advanced ALK-positive disease who were eligible for the clinical trial. Most of the patients had received previous treatment. These patients were enrolled in an expanded cohort study instituted after phase 1 dose escalation had established a recommended crizotinib dose of 250 mg twice daily in 28-day cycles. Patients were assessed for adverse events and response to therapy. Patients with ALK rearrangements tended to be younger than those without the rearrangements, and most of the patients had little or no exposure to tobacco and had adenocarcinomas. At a mean treatment duration of 6.4 months, the overall response rate was 57% (47 of 82 patients, with 46 confirmed partial responses and 1 confirmed complete response); 27 patients (33%) had stable disease. A total of 63 of 82 patients (77%) were continuing to receive crizotinib at the time of data cutoff, and the estimated probability of 6-month progression-free survival was 72%, with no median for the study reached. The drug resulted in grade 1 or 2 (mild) gastrointestinal side effects. The inhibition of ALK in lung tumors with the ALK rearrangement resulted in tumor shrinkage or stable disease in most patients. (Funded by Pfizer and others; ClinicalTrials.gov number, NCT00585195.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979469"}
{"pmid": "20979470", "title": "Effects of CYP2C19 genotype on outcomes of clopidogrel treatment.", "content": "Effects of CYP2C19 genotype on outcomes of clopidogrel treatment. It has been suggested that clopidogrel may be less effective in reducing the rate of cardiovascular events among persons who are carriers of loss-of-function CYP2C19 alleles that are associated with reduced conversion of clopidogrel to its active metabolite. We genotyped patients from two large, randomized trials that showed that clopidogrel, as compared with placebo, reduced the rate of cardiovascular events (the primary efficacy outcome) among patients with acute coronary syndromes and among patients with atrial fibrillation. Patients were genotyped for three single-nucleotide polymorphisms (*2, *3, *17) that define the major CYP2C19 alleles. Among 5059 genotyped patients with acute coronary syndromes, clopidogrel as compared with placebo significantly reduced the rate of the primary efficacy outcome, irrespective of the genetically determined metabolizer phenotype (P=0.12 for heterogeneity). The effect of clopidogrel in reducing the rate of the primary efficacy outcome was similar in patients who were heterozygous or homozygous for loss-of-function alleles and in those who were not carriers of the alleles (rate among carriers, 8.0% with clopidogrel vs. 11.6% with placebo; hazard ratio with clopidogrel, 0.69; 95% confidence interval [CI], 0.49 to 0.98; rate among noncarriers, 9.5% vs. 13.0%; hazard ratio, 0.72; 95% CI, 0.59 to 0.87). In contrast, gain-of-function carriers derived more benefit from clopidogrel treatment as compared with placebo than did noncarriers (rate of primary outcome among carriers, 7.7% vs. 13.0%; hazard ratio, 0.55; 95% CI, 0.42 to 0.73; rate among noncarriers, 10.0% vs. 12.2%; hazard ratio, 0.85; 95% CI, 0.68 to 1.05; P=0.02 for interaction). The effect of clopidogrel on bleeding did not vary according to genotypic subgroups. Among 1156 genotyped patients with atrial fibrillation, there was no evidence of an interaction with respect to either efficacy or bleeding between the study treatment and the metabolizer phenotype, loss-of-function carrier status, or gain-of-function carrier status. Among patients with acute coronary syndromes or atrial fibrillation, the effect of clopidogrel as compared with placebo is consistent, irrespective of CYP2C19 loss-of-function carrier status. (Funded by Sanofi-Aventis and Bristol-Myers Squibb; ClinicalTrials.gov number, NCT00249873.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979470"}
{"pmid": "20979471", "title": "Tiotropium bromide step-up therapy for adults with uncontrolled asthma.", "content": "Tiotropium bromide step-up therapy for adults with uncontrolled asthma. Long-acting beta-agonist (LABA) therapy improves symptoms in patients whose asthma is poorly controlled by an inhaled glucocorticoid alone. Alternative treatments for adults with uncontrolled asthma are needed. In a three-way, double-blind, triple-dummy crossover trial involving 210 patients with asthma, we evaluated the addition of tiotropium bromide (a long-acting anticholinergic agent approved for the treatment of chronic obstructive pulmonary disease but not asthma) to an inhaled glucocorticoid, as compared with a doubling of the dose of the inhaled glucocorticoid (primary superiority comparison) or the addition of the LABA salmeterol (secondary noninferiority comparison). The use of tiotropium resulted in a superior primary outcome, as compared with a doubling of the dose of an inhaled glucocorticoid, as assessed by measuring the morning peak expiratory flow (PEF), with a mean difference of 25.8 liters per minute (P<0.001) and superiority in most secondary outcomes, including evening PEF, with a difference of 35.3 liters per minute (P<0.001); the proportion of asthma-control days, with a difference of 0.079 (P=0.01); the forced expiratory volume in 1 second (FEV1) before bronchodilation, with a difference of 0.10 liters (P=0.004); and daily symptom scores, with a difference of -0.11 points (P<0.001). The addition of tiotropium was also noninferior to the addition of salmeterol for all assessed outcomes and increased the prebronchodilator FEV1 more than did salmeterol, with a difference of 0.11 liters (P=0.003). When added to an inhaled glucocorticoid, tiotropium improved symptoms and lung function in patients with inadequately controlled asthma. Its effects appeared to be equivalent to those with the addition of salmeterol. (Funded by the National Heart, Lung, and Blood Institute; ClinicalTrials.gov number, NCT00565266.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979471"}
{"pmid": "20979472", "title": "Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor.", "content": "Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor. Inflammatory myofibroblastic tumor (IMT) is a distinctive mesenchymal neoplasm characterized by a spindle-cell proliferation with an inflammatory infiltrate. Approximately half of IMTs carry rearrangements of the anaplastic lymphoma kinase (ALK) locus on chromosome 2p23, causing aberrant ALK expression. We report a sustained partial response to the ALK inhibitor crizotinib (PF-02341066, Pfizer) in a patient with ALK-translocated IMT, as compared with no observed activity in another patient without the ALK translocation. These results support the dependence of ALK-rearranged tumors on ALK-mediated signaling and suggest a therapeutic strategy for genomically identified patients with the aggressive form of this soft-tissue tumor. (Funded by Pfizer and others; ClinicalTrials.gov number, NCT00585195.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979472"}
{"pmid": "20979474", "title": "Clinical practice. Recurrent miscarriage.", "content": "Clinical practice. Recurrent miscarriage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979474"}
{"pmid": "20979475", "title": "Images in clinical medicine. A foreign body.", "content": "Images in clinical medicine. A foreign body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979475"}
{"pmid": "20979473", "title": "EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors.", "content": "EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors. The EML4 (echinoderm microtubule-associated protein-like 4)-ALK (anaplastic lymphoma kinase) fusion-type tyrosine kinase is an oncoprotein found in 4 to 5% of non-small-cell lung cancers, and clinical trials of specific inhibitors of ALK for the treatment of such tumors are currently under way. Here, we report the discovery of two secondary mutations within the kinase domain of EML4-ALK in tumor cells isolated from a patient during the relapse phase of treatment with an ALK inhibitor. Each mutation developed independently in subclones of the tumor and conferred marked resistance to two different ALK inhibitors. (Funded by the Ministry of Health, Labor, and Welfare of Japan, and others.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979473"}
{"pmid": "20979476", "title": "Case records of the Massachusetts General Hospital. Case 33-2010. A 22-year-old woman with blurred vision and renal failure.", "content": "Case records of the Massachusetts General Hospital. Case 33-2010. A 22-year-old woman with blurred vision and renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979476"}
{"pmid": "20979477", "title": "Crizotinib--latest champion in the cancer wars?", "content": "Crizotinib--latest champion in the cancer wars?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979477"}
{"pmid": "20979478", "title": "Products at risk.", "content": "Products at risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979478"}
{"pmid": "20979479", "title": "Anticholinergics for patients with asthma?", "content": "Anticholinergics for patients with asthma?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979479"}
{"pmid": "20979480", "title": "Stenting versus endarterectomy for carotid-artery stenosis.", "content": "Stenting versus endarterectomy for carotid-artery stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979480"}
{"pmid": "20979481", "title": "A school-based intervention for diabetes risk reduction.", "content": "A school-based intervention for diabetes risk reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979481"}
{"pmid": "20979482", "title": "Molecular architecture of the Goodpasture autoantigen.", "content": "Molecular architecture of the Goodpasture autoantigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979482"}
{"pmid": "20979483", "title": "Valproic acid use in pregnancy and congenital malformations.", "content": "Valproic acid use in pregnancy and congenital malformations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979483"}
{"pmid": "20979484", "title": "Early Alzheimer's disease.", "content": "Early Alzheimer's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979484"}
{"pmid": "20979485", "title": "Genetic disorders of renal phosphate transport.", "content": "Genetic disorders of renal phosphate transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979485"}
{"pmid": "20979486", "title": "Acupuncture for chronic low back pain.", "content": "Acupuncture for chronic low back pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979486"}
{"pmid": "20979491", "title": "Management of Clostridium difficile infection: thinking inside and outside the box.", "content": "Management of Clostridium difficile infection: thinking inside and outside the box. Treatment of Clostridium difficile infection (CDI) has relied on 2 antimicrobial agents, metronidazole and vancomycin, since the recognition of this disease entity. While effective, these \"inside the box\" approaches to CDI management have the disadvantage of further microbial disruption of the host indigenous microflora. \"Outside the box\" therapies use non-antimicrobial approaches to management and are theoretically less prone to causing recurrent CDI episodes. Recent advances in understanding of \"inside the box\" approaches include appreciation of the decreased efficacy of metronidazole overall and the superior efficacy of vancomycin for treatment of severe CDI, as well as a new agent under development, fidaxomicin, which appears to be equal in efficacy to vancomycin but with less risk of subsequent CDI recurrences. Several \"outside the box\" approaches have also entered clinical development, including use of monoclonal antibodies, active vaccination, luminal toxin binders, and nontoxigenic C. difficile. These reports provide optimism that more-effective management of CDI is forthcoming.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979491"}
{"pmid": "20979490", "title": "Incidence of cleft lip and palate in Uganda.", "content": "Incidence of cleft lip and palate in Uganda. The purpose of the study was to estimate the need for resources for cleft repairs in Uganda by determining the overall incidence of oral-facial clefts and the ratio of isolated cleft lip to isolated cleft palate to cleft lip and palate. A 1-year prospective study was implemented in seven hospitals and health centers with maternity units in and around Kampala. All live babies were examined for cleft lip and/or palate at birth. The birth of a baby with a cleft was communicated to the research coordinator by maternity staff, and the babies were assessed within 24 hours of delivery. Maternity data (live births) for each center were collected monthly to determine the denominator. Over the course of 1 year (February 1, 2008 to January 31, 2009), 26,186 babies were delivered. Nineteen babies had a cleft lip and/or palate, giving an incidence of 0.73 in 1000; 12 of the 19 babies (63.2%) had a cleft lip and palate, six (31.2%) had an isolated cleft lip, and only one (5.3%) had an isolated cleft palate. The ratio of boys to girls was 1.1∶1. The incidence of clefts in this study was 0.73 in 1000. With an estimated 1100 babies born with a cleft per year, this would result in the need for 1800 cleft repairs for babies in Uganda (695 babies needing two repairs each). These data will be helpful to advocate for and plan the necessary resources to effectively treat this condition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979490"}
{"pmid": "20979492", "title": "Current definitions of central line-associated bloodstream infection: is the emperor wearing clothes?", "content": "Current definitions of central line-associated bloodstream infection: is the emperor wearing clothes?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979492"}
{"pmid": "20979493", "title": "Risk of postdischarge infection with vancomycin-resistant enterococcus after initial infection or colonization.", "content": "Risk of postdischarge infection with vancomycin-resistant enterococcus after initial infection or colonization. Postdischarge risks of vancomycin-resistant Enterococcus (VRE) infection among carriers are unknown. We conducted a retrospective cohort study of 199 patients newly detected as VRE carriers. Fifteen patients (8%) developed 27 VRE infections in the 18 months after detection. Among 10 postdischarge infections, 2 involved bacteremia and 3 resulted in readmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979493"}
{"pmid": "20979494", "title": "Neonatologists' perceptions of antimicrobial resistance and stewardship in neonatal intensive care units.", "content": "Neonatologists' perceptions of antimicrobial resistance and stewardship in neonatal intensive care units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979494"}
{"pmid": "20979495", "title": "Questionable effectiveness of the QuantiFERON-TB Gold Test (Cellestis) as a screening tool in healthcare workers.", "content": "Questionable effectiveness of the QuantiFERON-TB Gold Test (Cellestis) as a screening tool in healthcare workers. The Center for Disease Control and Prevention recommends the use of QuantiFERON TB Gold test (QFTG; Cellestis) in all situations where the tuberculin skin test (TST) is used. In November 2007, our institution replaced its screening-tool TST with the QFTG in-tube assay (QFT-GIT) for annual screening of latent tuberculosis infection among healthcare workers (HCWs). This study evaluated the effectiveness of QFT-GIT test as screening tool in HCWs at our institution. This retrospective study reviewed medical records of all HCWs who underwent screening with QFT-GIT from January 2008 through December 2008. Among the 6,530 HCWs screened with QFT-GIT from January through December 2008, 287 had a positive test result. Of the 287, 123 had positive TST results in the past, meaning that 164 HCWs had newly diagnosed latent tuberculosis infection by QFT-GIT. Of the 164 HCWs, 135 were retested by QFT-GIT and were simultaneously tested with TST within 4 weeks after the initial QFT-GIT. Of these 135 HCWs, 66 reverted to negative results and results remained positive for 69 with QFT-GIT. Only 2 HCWs had a positive TST result. The disagreement between QFT-GIT and TST results and the high reversion rate with QFT-GIT raise concerns about the effectiveness of QFT-GIT as a sole screening test in HCWs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979495"}
{"pmid": "20979524", "title": "Geographic access to hospice in the United States.", "content": "Geographic access to hospice in the United States. Despite a 41% increase in the number of hospices since 2000, more than 60% of Americans die without hospice care. Given that hospice care is predominantly home based, proximity to a hospice is important in ensuring access to hospice services. We estimated the proportion of the population living in communities within 30 and 60 minutes driving time of a hospice. We conducted a cross-sectional study of geographic access to U.S. hospices using the 2008 Medicare Provider of Services data, U.S. Census data, and ArcGIS software. We used multivariate logistic regression to identify gaps in hospice availability by community characteristics. As of 2008, 88% of the population lived in communities within 30 minutes and 98% lived in communities within 60 minutes of a hospice. Mean time to the nearest hospice was 15 minutes and the range was 0 to 403 minutes. Community characteristics independently associated with greater geographic access to hospice included higher population density, higher median income, higher educational attainment, higher percentage of black residents, and the state not having a Certificate of Need policy. The percentage of each state's population living in communities more than 30 minutes from a hospice ranged from 0% to 48%. Recent growth in the hospice industry has resulted in widespread geographic access to hospice care in the United States, although state and community level variation exists. Future research regarding variation and disparities in hospice use should focus on barriers other than geographic proximity to a hospice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979524"}
{"pmid": "20979526", "title": "Should herbs take all the blame? Causality assessment of a serious thrombocytopenia event.", "content": "Should herbs take all the blame? Causality assessment of a serious thrombocytopenia event. With the increasing use of herbal medicines, the causality assessment of adverse drug-related reactions becomes more complicated because of the concomitant use of herbs and conventional medications. Epidemiological causal inference can be a central feature of such judgment but may be insufficient. Other scientific considerations include study design, bias, confounding, and measurement issues. The approach of this study is to establish an active safety surveillance system for finished herbal products (FHPs) and to review each adverse event regularly. A single case of serious thrombocytopenia was found in 136 subjects taking FHPs on a clinical trial for 12 weeks, for which the cause was sought. Because at the end of the first month the patient's platelet counts were normal and the thrombocytopenia developed after the co-medication with conventional drugs, it was suspected that the thrombocytopenia might not be attributed to the use of FHP. This report summarizes the criteria of causality assessment under mixed use of herbs and conventional medicine and recommends a feasible process for careful evaluation of adverse drug reactions related to all herbal medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979526"}
{"pmid": "20979497", "title": "Protein synthesis, degradation, and retention: mechanisms of indeterminate growth in cephalopods.", "content": "Protein synthesis, degradation, and retention: mechanisms of indeterminate growth in cephalopods. This study is the first to examine the underlying process of growth in a cephalopod, the southern dumpling squid (Euprymna tasmanica), to ascertain the mechanism by which indeterminate growth is achieved in this live-fast, die-young group of animals. This is the first study to estimate rates of protein synthesis and growth of squid from 7 to 140 d of age, providing an understanding of both the pattern and the process of growth throughout the lifetime of a squid species. Younger and smaller individuals had greater rates of protein synthesis and protein synthesis retention efficiency, as well as more RNA, than did older and larger individuals. Variation in growth rates among older, larger individuals was a function of individuals with faster growth rates having greater protein synthesis retention efficiency and also greater concentrations of protein. Critically, growth did not cease in the adults and, with an average of 10% of protein synthesized being retained, the mechanism to support the nonasymptotic growth model of cephalopods is provided.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979497"}
{"pmid": "20979529", "title": "C-reactive protein can influence the proliferation, apoptosis, and monocyte chemotactic protein-1 production of human umbilical vein endothelial cells.", "content": "C-reactive protein can influence the proliferation, apoptosis, and monocyte chemotactic protein-1 production of human umbilical vein endothelial cells. C-reactive protein (CRP) has been shown to be closely associated with coronary heart disease. The serum CRP concentrations of chronic periodontitis (CP) patients were increased due to periodontal inflammation. CRP may be a potential key mediator associating CP with coronary heart disease. This study aimed to investigate the effects of CRP on human endothelial cells in vitro. CRP ranging from 0 to 10 μg/mL was adopted to imitate the chronic inflammatory conditions of periodontitis. The influences of CRP on proliferation, apoptosis, and monocyte chemotactic protein-1 (MCP-1) production of human umbilical vein endothelial cells (HUVECs) were studied through 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, flow cytometry, and enzyme-linked immunosorbent assay analysis, respectively. Compared to the blank control, 2.5 and 5.0 μg/mL CRP significantly suppressed cell proliferation by 6.9% and increased apoptosis by 10.2% and 14.6%, respectively (p<0.05). Concentrations of 7.5 and 10.0 μg/mL CRP also induced 2.3% HUVEC proliferation suppression (p>0.05) and significantly increased apoptosis ratio compared to that of the blank control. CRP could promote MCP-1 production of HUVECs in a concentration-dependent manner. The MCP-1 production of 10.0 μg/mL CRP group was about 15.3% higher than that of the control group. It is concluded that low concentrations of CRP, which appears in CP, inhibits cell proliferation, promotes cell apoptosis, and increases MCP-1 production in endothelium, which may initiate self-repairing function of vascular endothelium following vascular injury process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979529"}
{"pmid": "20979530", "title": "Targeting the glycoprotein 130 receptor subunit to control pain and inflammation.", "content": "Targeting the glycoprotein 130 receptor subunit to control pain and inflammation. The glycoprotein 130 (gp130) is a shared signal-transducing-membrane-associated receptor for several hematopoietic cytokines. Its activation is implicated in pain and in a variety of diseases via signaling of proinflammatory cytokines. These include interleukin-6 (IL-6) subfamily cytokines, many of which play important roles in the pathogenesis of diseases such as rheumatoid arthritis, Castleman's disease, and Kaposi's sarcoma. Several strategies have been developed to block gp130-receptor-mediated signaling. These include the application of monoclonal antibodies, the creation of mutant form(s) of the gp130 with increased binding affinity for such ligands as IL-6/sIL-6R complex, and the generation of antagonists by selective mutagenesis of the specific cytokine/gp130 receptor binding site(s). Other strategies include targeting gp130-mediated signaling pathways such as that involving signal transducer and activator of transcription-3. This review provides a summary of the latest research pertaining to the role of gp130 in the pathogenesis of inflammatory and other diseases in which the gp130 receptor is implicated. An overview of antagonists targeting the gp130 receptor is included with particular emphasis on their mechanism of action and their limitations and potential for therapeutic application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979530"}
{"pmid": "20979528", "title": "Localization and characterization of rat transmembrane protein 225 specifically expressed in testis.", "content": "Localization and characterization of rat transmembrane protein 225 specifically expressed in testis. Testis is the one and only location of spermatogenesis and sexual hormone production. Spermatogenesis is a complicated physiological process regulated by many genes specifically and differentially expressed in the testis. In this study, Transmembrane Protein 225 (TMEM225), which is specifically expressed in rat testis, has been identified. TMEM225 was cloned from the testis cDNA library and was mapped to chromosome 8q22 by browsing the University of California Santa Cruz genomic database. It contains an open reading frame with a length of 696 bp, encoding a protein with four putative transmembrane helices. TMEM225 mRNA expression was evaluated by reverse transcription-polymerase chain reaction and in situ hybridization. In addition, the subcellular location of TMEM225 was evaluated. The results obtained highlighted age related specific expression of TMEM225 in testis, specifically during the adult period after age of 13 months. In situ hybridization analysis indicated that TMEM225 mRNA was mainly expressed in spermatocyte cells and round spermatids. Green fluorescence protein localization analysis showed that rat TMEM225 mainly surrounded the nuclear membrane, with a minority distribution in the cytoplasm, and the distribution of TMEM225 was affected by the deletion of N-terminal transmembrane domain. As the expression phase is not related to the first wave of spermatozoon development, our data presented here suggest that TMEM225 may play an important role in sperm degeneration but not in spermatogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979528"}
{"pmid": "20979498", "title": "A new comparative metric for estimating heterothermy in endotherms.", "content": "A new comparative metric for estimating heterothermy in endotherms. A major focus in the study of endothermic thermoregulation has been the description of thermoregulatory patterns used by various species and/or populations. Compared with ectotherms, relatively few attempts have been made to study the thermoregulation of endotherms in an adaptive framework. We believe that one of the main factors limiting this area of research has been the lack of an appropriate metric to directly compare body temperature (T(b)) variation across all endothermic species. Thus, we present a simple comparative metric, the heterothermy index (HI), to quantify the expression of heterothermy by endotherms during a given time frame. Key advantages of HI are that (1) it represents a new analytical technique that has different strengths than the metrics commonly used to describe variation in T(b), (2) it allows for evaluation of nonenergetic costs and benefits that affect the expression of heterothermy, and (3) it has the potential to unify research on homeotherms and heterotherms through quantitative comparative analyses that examine the entire continuum of thermoregulatory patterns. In short, we suggest that our metric provides a means to overcome one of the hurdles presently slowing the advancement of research on endothermic thermoregulation beyond the simple description of thermoregulatory patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979498"}
{"pmid": "20979531", "title": "Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells.", "content": "Ezh2 expression in astrocytes induces their dedifferentiation toward neural stem cells. Recently, we have demonstrated the expression of the polycomb group protein Ezh2 in embryonic and adult neural stem cells. Although Ezh2 remained highly expressed when neural stem cells differentiate into oligodendrocyte precursor cells, it is downregulated during the differentiation into neurons or astrocytes. This is in accordance with the differentiation repressive role Ezh2 is thought to play in the maintenance and self-renewal of stem cells. To establish the importance of downregulation of Ezh2 for becoming astrocytes, we have studied the effect of forced Ezh2 expression in postnatal mouse astrocytes. Upon forced expression of this polycomb group protein, cultured astrocytes retracted their cell extensions and became proliferating round/bipolar cells that occasionally formed small neurosphere-like clusters. Analysis of the expression profile of these Ezh2-expressing astrocytes reveal downregulation of typical astrocytic genes, like GFAP and S100, and upregulation of genes that are generally expressed in neural stem cells, like nestin, Sox2, musashi, and CD133. However, these neural stem cell-like cells lack a differentiation potential, indicating that overexpression of Ezh2 alone is insufficient for a complete dedifferentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979531"}
{"pmid": "20979532", "title": "The mouse alpha-albumin (afamin) promoter is differentially regulated by hepatocyte nuclear factor 1α and hepatocyte nuclear factor 1β.", "content": "The mouse alpha-albumin (afamin) promoter is differentially regulated by hepatocyte nuclear factor 1α and hepatocyte nuclear factor 1β. Alpha-albumin (AFM), a member of the albumin gene family that also includes albumin, alpha-fetoprotein, and vitamin D-binding protein, is expressed predominantly in the liver and activated at birth. Here, we identify two hepatocyte nuclear factor 1 (HNF1)-binding sites in the AFM promoter that are highly conserved in different mammals. These two sites bind HNF1α and HNF1β. The distal site (centered at -132, relative to AFM exon 1) is more important than proximal site (centered at -58), based on HNF1 binding and mutational analysis in transfected cells. Our data indicate that HNF1α is a more potent activator of AFM promoter than is HNF1β. However, HNF1β can act in a dominant manner to inhibit HNF1α-dependent transactivation of the AFM promoter when both proteins are expressed together. This suggests that the differential timing with which the albumin family genes are activated in the liver may be influenced by their responsiveness to HNF1α and HNF1β. Our comparison of HNF1-binding sites in the promoters in the albumin family of genes indicates that the primordial albumin-like gene contained two HNF1 sites; one of these sites was lost from the albumin promoter, but both sites still are present in other members of this gene family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979532"}
{"pmid": "20979533", "title": "Effects of extracellular matrix density and mesenchymal stem cells on neovascularization in vivo.", "content": "Effects of extracellular matrix density and mesenchymal stem cells on neovascularization in vivo. Aberrant angiogenesis is common to a variety of diseases in which alterations in tissue mechanical properties also occur. A fundamental understanding of the interdependence of angiogenesis and tissue structural properties may enhance the development of therapeutic strategies. We previously established that increasing extracellular matrix density inhibits capillary morphogenesis in three-dimensional tissues in vitro, and that addition of human mesenchymal stem cells (MSCs) partially rescues a healthy angiogenic phenotype. This study's goal was to investigate if these effects can be recapitulated in vivo. Human umbilical vein endothelial cells, MSCs, or a mixture of both was suspended in fibrin gel precursor solutions of 5, 10, and 15 mg/mL concentrations and injected subcutaneously into SCID mice. Neovascularization was assessed in tissue constructs retrieved at 3, 7, and 21 days by quantifying vessel numbers, perfusion, thickness, maturity, and perivascular collagen deposition. The data show that changing extracellular matrix density inhibits capillary morphogenesis in vivo in a manner consistent with that observed in vitro. Delivery of both human umbilical vein endothelial cells and MSCs produced more robust and mature vessels than delivery of either cell type alone in all tissue concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979533"}
{"pmid": "20979534", "title": "Biophysical properties and oxygenation potential of high-molecular-weight glutaraldehyde-polymerized human hemoglobins maintained in the tense and relaxed quaternary states.", "content": "Biophysical properties and oxygenation potential of high-molecular-weight glutaraldehyde-polymerized human hemoglobins maintained in the tense and relaxed quaternary states. Recent clinical evaluation of commercial glutaraldehyde-polymerized hemoglobins (PolyHbs) as transfusion solutions has demonstrated several adverse side effects. Chief among these is the hypertensive effect. Fortunately, previous studies have shown that the hypertensive effect can be attenuated by removing free hemoglobin (Hb) and low-molecular-weight (low-MW) PolyHbs from the PolyHb mixture. In this work, polymerized human Hb (PolyhHb) solutions were synthesized in two distinct quaternary states with high MW and subjected to extensive diafiltration to remove free Hb and low-MW PolyhHb components (<500 kDa). The resultant PolyhHb solutions possessed high MW, distinct quaternary state, distinct reactivities with O(2) and CO, similar NO deoxygenating rate constants, distinct autoxidation rate constants, high viscosity, and low colloid osmotic pressure. To preliminarily assess the ability of PolyhHb solutions to oxygenate surrounding tissues fed by a blood vessel, we evaluated the ability of PolyhHbs to transport O(2) to cultured hepatocytes in a mathematical model of a hollow fiber bioreactor. The structure of individual hollow fibers in the bioreactor is similar to that of a blood vessel and provides an easy way to assess the oxygenation potential of PolyhHbs without the need for expensive and time-consuming animal studies. It was observed that PolyhHbs with low O(2) affinities were more effective in oxygenating cultured hepatocytes inside the bioreactor than high O(2) affinity PolyhHbs. Taken together, our results show that it is possible to synthesize high-MW PolyhHbs with no free Hb and low-MW PolyhHb components that are capable of transporting O(2) to cultured cells/tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979534"}
{"pmid": "20979535", "title": "Combined gene therapy with hypoxia-inducible factor-1α and heme oxygenase-1 for therapeutic angiogenesis.", "content": "Combined gene therapy with hypoxia-inducible factor-1α and heme oxygenase-1 for therapeutic angiogenesis. Transfection with either hypoxia-inducible factor-1α (HIF-1α) or heme oxygenase-1 (HO-1) gene can induce neovascularization in ischemic tissues. Although expression of transfected HIF-1α gene occurs rapidly, the expressed HIF-1α protein degrades quickly, limiting its therapeutic efficacy. Meanwhile, expressed HO-1 protein does not rapidly undergo degradation, but gene expression occurs a couple of days after transfection, resulting in apoptosis and a delay in angiogenesis in ischemic tissues at the incipient period of HO-1 gene transfection. We hypothesize that combined delivery of HIF-1α and HO-1 gene will enhance antiapoptosis and neovascularization in ischemic tissue compared with HIF-1α or HO-1 single-gene therapy. To test this hypothesis, ischemic mouse hindlimbs were treated with HIF-1α and/or HO-1 gene therapy. The combined gene therapy proved superior to both single-gene therapies, resulting in rapid expression of HIF-1α gene and long-term maintenance of expressed HO-1 protein. The apoptosis in the ischemic region was significantly less, and angiogenic growth factor secretion and angiogenesis were greater in the combined gene therapy than in either of the single-gene therapies. Our results suggest that a combined gene therapy of HIF-1α and HO-1 enhances the transfection of both genes and improves angiogenesis compared with either single-gene therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979535"}
{"pmid": "20979536", "title": "Takotsubo cardiomyopathy in acute coronary syndrome; clinical features and contribution of cardiac magnetic resonance during the acute and convalescent phase.", "content": "Takotsubo cardiomyopathy in acute coronary syndrome; clinical features and contribution of cardiac magnetic resonance during the acute and convalescent phase. Takotsubo cardiomyopathy (TTC) is a diagnostic entity that is increasingly being recognized. Data from cardiac magnetic resonance (CMR) imaging and its impact on differential diagnosis are limited. After 26 months, coronary angiography revealed normal coronary arteries and left ventriculography and/or echocardiography left ventricular dysfunction with apical ballooning in 20 patients with acute coronary syndrome (ACS). Four patients were excluded from CMR and in three patients an alternative diagnosis was revealed. Thirteen patients (all female; 60 ± 8 years) with TTC underwent a multisequential CMR, in which all showed myocardial oedema with an elevated T2 ratio in the apical region (2.4 ± 0.4; p < 0.001 vs. healthy controls), and five patients an elevated global relative enhancement (gRE; 3.7 ± 1.4; p < 0.05 vs. healthy controls). No late gadolinium enhancement (LGE) was detected on CMR. Follow-up after 132 ± 33 days showed a normalized left ventricular ejection fraction, myocardial mass, T2 ratio, and gRE in all patients. TTC is a small but definite group among patients with ACS and normal coronary arteries. CMR allows differentiating TTC from other causes such as myocarditis and cardiomyopathies, as well as to identify the transient increase of myocardial mass and resolution of myocardial oedema as the systolic dysfunction improves. Therefore, CMR might add valuable information for the differential diagnoses and therapeutic decision-making in patients with suspected TTC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979536"}
{"pmid": "20979537", "title": "Plants used for the treatment of diabetes in Jordan: a review of scientific evidence.", "content": "Plants used for the treatment of diabetes in Jordan: a review of scientific evidence. Diabetes is a serious disease which has reached epidemic proportions in many parts of the world. Despite the tremendous developments in medicinal chemistry, traditional medicine is still a common practice for the treatment of diabetes. In Jordanian traditional medicine, 69 plant species are used by diabetic patients to reduce glucose levels in blood. The aim of the present study is to report these plants and link their traditional use with scientific evidence confirming their claimed activity. The plant part(s) used, method(s) of preparation, common Arabic names, and other ethnopharmacological uses are also listed. The literature and databases (SciFinder, PubMed, ScienceDirect and Scirus) have been thoroughly investigated and the plants used have been grouped according to the reported scientific evidence. Results showed that 40 plants have been reported to possess hypoglycemic activities in in vivo/in vitro experiments. Five plant species did not exhibit in vivo hypoglycemic activity, while 24 plants had not been studied for such an activity. Twenty plants had been screened for their α-amylase/α-glucosidase inhibitory activities. The reported in vivo and in vitro hypoglycemic as well as α-amylase/α-glucosidase inhibitory activities of these plants are discussed. Additional in vitro and in vivo studies are needed to test the hypoglycemic activity of the plants with claimed antidiabetic activity which has not yet been evaluated. Identification of the active ingredients of potent plants might generate lead compounds in drug discovery and development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979537"}
{"pmid": "20979496", "title": "Diel patterns of nitrogen excretion, plasma constituents, and behavior in the gulf toadfish (Opsanus beta) in laboratory versus outdoor mesocosm settings.", "content": "Diel patterns of nitrogen excretion, plasma constituents, and behavior in the gulf toadfish (Opsanus beta) in laboratory versus outdoor mesocosm settings. Nitrogen excretion by the gulf toadfish (Opsanus beta) is of interest because of its high proportion of urea excretion compared with that of other teleosts. To better understand the factors influencing the timing of nitrogen excretion, the ratio of excreted urea∶ammonia, and the effector molecules regulating these processes, gulf toadfish were subjected to a series of experiments that moved them progressively from internal laboratory to outdoor mesocosm settings while assessing their behavior, nitrogen excretion patterns, levels of plasma hormones/effectors, and other parameters. In confined flux chambers in both laboratory and outdoor settings, toadfish nitrogen excretion was largely observed as urea pulses, with no apparent diel patterns to the pulses. Unrestrained toadfish in mesocosms exhibited distinctly nocturnal behavior, remaining exclusively in shelters during the day but taking several forays out into the mesocosm at night. In contrast to nitrogen excretion patterns in chambers, urea and ammonia were coexcreted in mesocosms and ratios for urea∶ammonia were very close to 1∶1 for both fed and fasted toadfish. The majority of measured excretion (and corresponding declines in plasma urea levels) occurred during two distinct periods of pulsing during daylight hours (0600-1000 and 1600-1800 hours). The declines in plasma urea associated with excretion were preceded by/coincided with declines in plasma cortisol. No day/night or hourly patterns in plasma serotonin (5-hydroxytryptamine [5-HT]) were observed, but there was a strong positive correlation among all samples between plasma urea and 5-HT. There was also a negative correlation between plasma cortisol and 5-HT. As expected for a nocturnally active species, plasma melatonin was significantly lower in daylight hours. A variety of enzyme activities (glutamine synthetase, glutaminase) and mRNA levels (glutamine synthetase, urea transporter, and Rhesus proteins) showed no significant variation over a diel cycle. Unlike prior laboratory studies, our results show that gulf toadfish in a natural setting have a distinctly diurnal pattern of nitrogen excretion and that ammonia and urea are coexcreted. The decline in plasma cortisol associated with urea pulses noted in prior laboratory studies was not as evident in the natural setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979496"}
{"pmid": "20979538", "title": "Protective effects of the aqueous extract of Scutellaria baicalensis against acrolein-induced oxidative stress in cultured human umbilical vein endothelial cells.", "content": "Protective effects of the aqueous extract of Scutellaria baicalensis against acrolein-induced oxidative stress in cultured human umbilical vein endothelial cells.  Scutellaria baicalensis Georgi (Labiatae) (SbG), one of the fifty fundamental herbs of Chinese herbology, has been reported to have anti-asthmatic, antifungal, antioxidative, and anti-inflammatory activities.  This study was designed to determine the protective effects of the extract of SbG against the acrolein-induced oxidative stress in cultured human umbilical vein endothelial cells (HUVEC).  The MTT reduction assay was employed to determine cell viability. The total cellular glutathione (GSH) level was detected using a colorimetric GSH assay kit. Cellular GSH production was conducted by detecting the mRNA expression levels of γ-glutamylcysteine ligase catalytic subunit and modifier subunit.  Concentration-dependent cytotoxic effects of acrolein were observed while SbG could effectively protect the acrolein-induced oxidative damage. The protective mechanism was investigated, showing that the increased GSH content in the SbG-incubated HUVE cells was associated with the protective effects of SbG-treated cells. Further RT-PCR data confirmed the elevated mRNA expressions of GSH synthesis enzymes.  The current study strongly indicated that SbG could be a potential antioxidant against oxidative stress in treating cardiovascular diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979538"}
{"pmid": "20979539", "title": "Intrafollicular and serum levels of leptin during in vitro fertilization cycles: comparison between the effects of recombinant follicle-stimulating hormones and human menopausal gonadotrophin.", "content": "Intrafollicular and serum levels of leptin during in vitro fertilization cycles: comparison between the effects of recombinant follicle-stimulating hormones and human menopausal gonadotrophin. To compare the effect of recombinant follicle-stimulating hormones (r-FSH) and human menopausal gonadotrophin (hMG) on leptin levels in serum and follicular fluid (FF) during in vitro fertilization IVF/ET treatment, and to investigate whether leptin levels in the follicular fluid and/or serum are correlated with IVF success. Sixty-three patients undergoing IVF cycle were subdivided into two groups. r-FSH was used to for controlled ovarian hyperstimulation in 29 patients (Group A) while, hMG was used in 34 patients (Group B). Our main outcomes were serum and FF leptin on the day of oocyte collection. The two groups were comparable in age, body mass index (BMI), indications for IVF/ET, E2 level on human chorionic gonadotrophin day, number of retrieved oocytes, fertilization rate, number of transferred embryos and pregnancy rate. Serum and FF leptin levels were similar between the two study groups. Additionally, no correlation was found between levels of leptin in either serum or FF and cycle results such as: number of retrieved oocytes, fertilization rate and pregnancy rate. r-FSH and hMG have been found to have comparable effects on leptin levels in the serum and the FF of patients undergoing IVF/ET. Additionally, leptin levels in both serum and FF on day of retrieval have no correlation to IVF/ET outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979539"}
{"pmid": "20979541", "title": "Optimizing soy isoflavones effect in postmenopausal women: the impact of timing on climacteric symptoms.", "content": "Optimizing soy isoflavones effect in postmenopausal women: the impact of timing on climacteric symptoms. The most common complaints during climacteric are vasomotor symptoms. A circadian rhythm has been observed when hot flashes start; however, not much information is available in this field. To analyze whether the time (morning/evening) of administration of a compound containing 60 mg of dry soy seed extract (glycine max) with 40% of total isoflavones, primrose oil and α-tocopherol modifies the effect on the climacteric syndrome. Multicentric, observational, open, prospective, longitudinal and cross-sectional study. Subjects and methods. One thousand six hundred eighty-two postmenopausal women with climacteric symptoms were allocated in two groups in order to receive the treatment in the morning (Group 1) or in the evening (Group 2), switching administration time after 3 months. Clinical evaluation was carried out at 0, 3 and 6 months of follow-up using Blatt-Kupperman and Greene scales. 233 (13.9%) women dropped out from the study. Both administration times improved the climacteric symptoms after 3 and 6 months of treatment, showing a reduction in the scores of Blatt-Kupperman and Greene scales (p < 0.001). No differences between both groups during the follow-up were identified. The time of administration of isoflavones does not modify its effect on climacteric symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979541"}
{"pmid": "20979540", "title": "Changes in hemostatic parameters after oral and transdermal hormone therapy in postmenopausal women.", "content": "Changes in hemostatic parameters after oral and transdermal hormone therapy in postmenopausal women. Hormone therapy (HT) can be prothrombotic risk factor. We compared the effects of oral HT (o-HT) and transdermal HT (t-HT) on the kinetic of clot formation and fibrinolysis in postmenopausal women after 6 months HT using a multiparameter test. We observed that after HT, the level of fibrinogen was higher than in controls (Fg 3.12 g/l vs. 4.24 g/l (o-HT); 3,7 g/l (t-HT); p < 0.001) and values of velocity of polymerization in o-HT group were increased (95.84 mOD/min vs. 146.50 mOD/min, p < 0.001) compared to controls. Maximum absorbance of formed clots was higher in o-HT group (0.279 vs. 0.312, p < 0.001) than in controls, but in t-HT group was lowest (0.268). Fibrin lysis half-time increased in both HT groups (controls 17.16 min vs. 31.43 min (o-HT); 23.34 min (t-HT) p < 0.001) compared to values in controls. The results of our study show that o-HT caused the changes in clot formation and fibrinolysis than t-HT in postmenopausal women. The increased level of fibrinogen and its accelerated kinetics of polymerization as well as a lower rate of clot lysis may partly explain the increase in venous thrombosis and cardiovascular events reported after the use of HT, especially the oral form of that.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979540"}
{"pmid": "20979542", "title": "Anti-inflammatory activity of Penstemon gentianoides and Penstemon campanulatus.", "content": "Anti-inflammatory activity of Penstemon gentianoides and Penstemon campanulatus. Penstemon gentianoides (Kunth) Poir. and Penstemon campanulatus (Cav.) Willd. (Plantaginaceae) are important medicinal plants in Mexico used by indigenous people for their anti-inflammatory effects and to also reduce rheumatic pains. In addition to radical scavenging activity, the anti-inflammatory activity of the extracts, fractions and compounds of these plants were investigated and reported here for the first time. The anti-inflammatory activities of MeOH, CH(2)Cl(2), and ethyl acetate extracts and iridoid, flavonoids, and phenylpropanoids from Penstemon gentianoides and P. campanulatus were studied in the TPA-induced mouse ear edema model. In addition, antioxidant activity against DPPH, crocin and β-carotene were investigated. All extracts were tested and a selection of known compounds significantly (p <0.05) inhibited mouse ear edema. The results showed that CH(2)Cl(2) extracts of roots and stems from P. gentianoides and ethyl acetate extracts of leaves from P. gentianoides and P. campanulatus, as well as luteolin, diosmetin, penstemide and verbascoside produced the most positive results. Of all substances tested, the CH(2)Cl(2) extract of P. gentianoides roots was the most powerful inhibitor (ED(50)=0.07 mg/ear), with activity comparable to that of indomethacin. These extracts, compounds purified, as well as known compounds, inhibited oxidation of β-carotene and crocin. These findings showed that the iridoid monoterpenes, flavonoids and phenylpropanoids present in these plants species may all contribute to the observed anti-inflammatory activity. Additionally, the observed antioxidant activity is correlated with the anti-inflammatory activity of these plants and the phytochemicals derived from them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979542"}
{"pmid": "20979543", "title": "BRCA1 and BRCA2 heterozygosity in embryonic stem cells reduces radiation-induced Rad51 focus formation but is not associated with radiosensitivity.", "content": "BRCA1 and BRCA2 heterozygosity in embryonic stem cells reduces radiation-induced Rad51 focus formation but is not associated with radiosensitivity. The breast cancer susceptibility genes BRCA1 (breast cancer 1) and BRCA2 (breast cancer 2) encode proteins involved in double-strand break (DSB) repair, whose functions include facilitating homologous recombination through interactions with Rad51, the human homologue of bacterial RecA. Homozygous deficiency inhibits Rad51 focus formation and enhances radiosensitivity, but the effects of heterozygosity have not been investigated in detail. The purpose of this work was to examine the effect of heterozygosity on Rad51 activation and clonogenicity following X-irradiation (XR). We used quantitative assessment of immunofluorescent foci to assess Rad51 activation in wild type mouse embryonic fibroblasts (MEF) and in paired mutant and wild type BRCA1 and BRCA2 embryonic stem cells (ES cells). We measured radiosensitivity in the same cell lines using clonogenic survival assays. ES cells exhibit higher numbers of cells with Rad51 foci post radiation than MEF, likely due to differences in cell cycle distribution. Compared to wild type cells, BRCA1 and BRCA2 heterozygous ES cells demonstrate lower numbers of Rad51 foci per nucleus 4 and 24 hours post radiation. This was not associated with significantly enhanced radiosensitivity. BRCA1/2 heterozygosity in ES cells is associated with a subtle reduction in Rad51 foci formation that is not associated with increased XR induced cytotoxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979543"}
{"pmid": "20979544", "title": "The alteration of asymmetric dimetilarginine (ADMA) levels in cardiac and gastrocnemius muscles following radioactive iodine application in guinea pigs and the effect of L-carnitine on this alteration.", "content": "The alteration of asymmetric dimetilarginine (ADMA) levels in cardiac and gastrocnemius muscles following radioactive iodine application in guinea pigs and the effect of L-carnitine on this alteration. Tissue levels of asymmetric dimetilarginine (ADMA) and symmetric dimetilarginine (SDMA) were investigated in cardiac ventricle and gastrocnemius muscles of guinea pigs treated with radioactive iodine (RAI) alone or in combination with L-carnitine (LC). Group 1 received no treatment (control group). Group 2 received a total dose of 30 mCi⁻¹kg⁻¹ body weight iodine-131 alone. Group 3 received 200 mg⁻¹kg⁻¹ of LC for 10 days alone. Group 4 received 200 mg⁻¹kg⁻¹ of LC plus RAI therapy. Free thyroid hormones, ADMA and SDMA concentrations were measured. Serum free thyroid hormone concentrations were found decreased in the RAI and LC-RAI groups after RAI application. A significant decrease in ADMA and SDMA concentration was observed in ventricle muscle following RAI application. The LC-RAI group had significantly decreased ADMA levels in ventricle muscle compared with those of the control group. Similarly, SDMA concentrations in ventricle and gastrocnemius muscles of the LC-RAI groups were significantly lower than those of the control groups. Our results indicated that RAI appears to exert an inhibitory effect on ADMA and SDMA levels of ventricular muscle. LC administration when given adjuvant to RAI therapy may cause a marked decrease in ADMA concentrations of both ventricular and gastrocnemius muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979544"}
{"pmid": "20979545", "title": "Body size and growth from birth to 2 years and risk of overweight at 7-9 years.", "content": "Body size and growth from birth to 2 years and risk of overweight at 7-9 years. To assess the potential association between growth during the first 2 years of life and the risk of overweight in childhood. Overweight status of 1 582 French children aged 7-9 years in 2000 was estimated, using measured weight and height data collected retrospectively. Overweight was estimated using measured weight and height. Linear mixed models identified six growth parameters associated with later overweight: weight, length and body mass index (BMI) attained at 1 year, average monthly weight and length gain, and average variation in monthly weight gain. In the combined logistic regression model, the risk of overweight in boys at 7-9 years was associated with average monthly weight gain (odds ratio [OR] for 100 g=2.06, 95% confidence interval [CI]: 1.22, 3.48) and BMI at 1 year (OR for 1 kg/m(2)=1.83, CI: 1.33, 2.51), while in girls, it was associated with weight at 1 year (OR for 1 kg=2.24, CI: 1.37, 3.66), BMI at 1 year (OR for 1 kg/m(2)=1.58, CI: 1.05, 2.39) and average variation in monthly weight gain (OR for 1 g=1.13, CI: 1.04, 1.22). This study showed the simultaneous association of large infant size at 1 year and early rapid infant growth along with overweight at 7-9 years, as well as involvement of early growth velocity variations. Early infancy, a phase of very rapid growth, constitutes a critical period for the onset of overweight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979545"}
{"pmid": "20979546", "title": "Treatment of cancer during pregnancy with monoclonal antibodies: a real challenge.", "content": "Treatment of cancer during pregnancy with monoclonal antibodies: a real challenge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979546"}
{"pmid": "20979548", "title": "Canakinumab: a human anti-IL-1β monoclonal antibody for the treatment of cryopyrin-associated periodic syndromes.", "content": "Canakinumab: a human anti-IL-1β monoclonal antibody for the treatment of cryopyrin-associated periodic syndromes. The cryopyrin-associated periodic syndromes (CAPS) are a group of rare inherited inflammatory diseases associated with overproduction of IL-1β. Canakinumab, developed by Novartis AG (Basel, Switzerland), is an intravenously or subcutaneously administered, fully human monoclonal antibody that neutralizes the bioactivity of human IL-1β. Canakinumab has promising clinical safety and pharmacokinetic properties, and has demonstrated potential for the treatment of CAPS. Canakinumab was recently granted EU orphan drug status for systemic-onset juvenile idiopathic arthritis, and early clinical trials have established that administration of canakinumab every 2 weeks is both safe and effective. Subcutaneous canakinumab (approved formulation) offers some advantages over the existing IL-1β-blocking treatment, anakinra, which must be injected daily and is often not well tolerated by patients. The long-term safety of all targeted anti-IL-1 therapies in CAPS remains an unanswered question owing to the relatively short clinical experience with these agents; as canakinumab produces sustained IL-1 suppression, vigilance is necessary to diagnose the development of adverse events, especially any associated infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979548"}
{"pmid": "20979549", "title": "Tocilizumab for the treatment of rheumatoid arthritis.", "content": "Tocilizumab for the treatment of rheumatoid arthritis. Tocilizumab is a humanized anti-IL-6 receptor monoclonal antibody, which binds to circulating soluble IL-6 receptor and membrane-expressed IL-6 receptor, inhibiting IL-6 binding to both forms of IL-6 receptor. Several Phase III clinical trials demonstrate the clinical efficacy of tocilizumab as monotherapy or with disease-modifying anti-rheumatic drugs for adult patients with moderately to severely active rheumatoid arthritis. Tocilizumab in combination with methotrexate after 24 weeks of treatment could induce disease remission in 30% of patients with rheumatoid arthritis refractory to anti-TNF antagonist therapy. The most common adverse reactions reported in clinical studies are upper respiratory tract infection, nasopharyngitis, headache, hypertension and mild, reversible increases in alanine aminotransferase enzymes. Serious adverse reactions include infections, gastrointestinal perforations and hypersensitivity reactions, including anaphylaxis. The clinical efficacy and safety of tocilizumab has led to the approval of this innovative drug for the treatment of rheumatoid arthritis in more than 70 countries worldwide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979549"}
{"pmid": "20979551", "title": "3,4-diaminopyridine for the treatment of Lambert-Eaton myasthenic syndrome.", "content": "3,4-diaminopyridine for the treatment of Lambert-Eaton myasthenic syndrome. The Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease in which antibodies against voltage-gated calcium channels inhibit cholinergic neurotransmission. LEMS is clinically characterized by muscle weakness and autonomic dysfunction. 3,4-diaminopyridine (3,4-DAP) blocks potassium channels in nerve terminals, resulting in an increase in acetylcholine release. This article describes the four randomized placebo-controlled trials of 3,4-DAP in patients with LEMS. All trials demonstrated a significant effect on muscle strength and compound muscle action potential amplitude. Furthermore, the safety and tolerability of 3,4-DAP are reviewed. The side effects of 3,4-DAP are generally mild and most frequently consist of paresthesias, but epileptic seizures and arrhythmias have been described in patients using high doses. Given the efficacy and safety of 3,4-DAP in LEMS, this drug is the mainstay for symptomatic treatment of LEMS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979551"}
{"pmid": "20979550", "title": "Certolizumab pegol: a new biologic targeting rheumatoid arthritis.", "content": "Certolizumab pegol: a new biologic targeting rheumatoid arthritis. The past decade has been an exciting period for clinical research and patient care in rheumatoid arthritis. This is mostly due to targeted biologic agents that have changed the outcome of this disease. Certolizumab pegol (Cimzia(®), UCB Inc., GA, USA), which targets TNF-α with a different mechanism of action than widely used biologics, was initially investigated for Crohn's disease but has now been shown to be effective for rheumatoid arthritis. There have been three significant clinical trials demonstrating the efficacy of certolizumab pegol in active rheumatoid arthritis; two with combination methotrexate and one with monotherapy. This article will summarize the data from those trials and compare some of the characteristics of certolizumab pegol to conventional disease-modifying antirheumatic drugs and other biologic agents. Treatment recommendations are beyond the scope of this review; however, with many options available, there will be annotations on current trends in the care of this chronic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979550"}
{"pmid": "20979552", "title": "Illuminating the latest advances in innate immunity on the island of the sun god.", "content": "Illuminating the latest advances in innate immunity on the island of the sun god. The latest Aegean Conferences workshop on innate immunity (Rhodes, Greece) discussed recent developments that suggest that innate immune mechanisms are not restricted to providing first-line defense or instructing the development of adaptive immunity, but additionally permeate and influence diverse physiological and homeostatic processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979552"}
{"pmid": "20979553", "title": "Finding the right time for weaning off immunosuppression in solid organ transplant recipients.", "content": "Finding the right time for weaning off immunosuppression in solid organ transplant recipients. Solid organ transplantation (SOT) requires lifelong immunosuppression (IS) to prevent rejection and graft loss. The currently adopted immunosuppressive protocols are numerous and are based on the administration of at least two molecules with diverse mechanisms of action. Owing to the fact that the majority of immunosuppressants act non-selectively, the immune system is normally oversuppressed, and as a result is less able to both defend the host against infection and to control the spread of malignant cells. Consequently, long-term IS is burdened by chronic toxicity, which may be highly invalidating and may significantly influence patient's quality of life, compliance to treatment, overall success rate, and patient and graft survival. In an ideal scenario, SOT recipients should initially receive just enough IS to favor the onset of clinical operational tolerance (COT), a condition where the immune system of the host does not attack the graft in the absence of any immunosuppressant. COT has been documented after liver transplantation (LT) and renal transplantation (RT). First, COT was accidentally detected in patients who were nonadherent to treatment and who spontaneously decided to stop all IS without any medical guidance or surveillance. Later, it was described in recipients who required IS withdrawal following the occurrence of malignant diseases. Based on strikingly convincing experimental data, several tolerogenic protocols have recently been applied in patients but overall the results have been disappointing. The current literature demonstrates that COT can be safely achieved in stable LT recipients, with completely different strategies. Importantly, the onset of an episode of acute rejection during the attempt of IS withdrawal would not worsen the clinical outcome. On the contrary, COT remains a major challenge after RT because the onset of acute rejection will substantiate in graft loss. Currently, a major field of investigation aims to define markers of COT, which will allow the selection of individuals who are more prone to develop COT. Preliminary results in both RT and LT have just been announced; however, these markers will require validation in prospective studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979553"}
{"pmid": "20979554", "title": "ABO blood group incompatibility: a diminishing barrier to successful kidney transplantation?", "content": "ABO blood group incompatibility: a diminishing barrier to successful kidney transplantation? Blood type-incompatible transplantation has gained wide acceptance over the last decade. This is largely the result of B-cell-directed therapies aimed at modulating anti-blood group antibodies, which were the cause of the poor outcomes originally seen. Now rituximab (anti-CD20 and anti-B cell) has largely replaced splenectomy in preconditioning protocols, allowing for the wider implementation of ABO-incompatible transplants. Plasma exchange followed by intravenous immunoglobulin is also critical for the success of ABO-incompatible transplants. In this article, we describe the important contributions immunomodulatory drugs and antibody reduction therapies have made in achieving excellent outcomes in what was once an impenetrable barrier to transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979554"}
{"pmid": "20979555", "title": "Treatment of lupus nephritis.", "content": "Treatment of lupus nephritis. Renal involvement in systemic lupus erythematosus patients is a severe disease manifestation characterized by various clinical and histopathological alterations. The revised International Society of Nephrology/Renal Pathology Society 2003 classification defines the subclasses of lupus nephritis (LN) according to their pathological glomerular patterns, which has a crucial impact on the prognosis and treatment options for LN patients. There are widely accepted therapeutic agents available, such as cyclophosphamide, mycophenolate mofetil, azathioprine and corticosteroids. Several trials have tried to determine a gold standard for induction and maintenance therapy in LN, and the place of newer drugs, biologicals, has been investigated. We review recently reported data on current treatment regimens in LN, in particular in the context of the International Society of Nephrology/Renal Pathology Society 2003 classification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979555"}
{"pmid": "20979556", "title": "Current understanding and management of giant cell arteritis and polymyalgia rheumatica.", "content": "Current understanding and management of giant cell arteritis and polymyalgia rheumatica. Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are linked conditions that occur in the elderly. GCA is a vasculitis of large- and medium-sized vessels causing critical ischemia. It is a medical emergency owing to the high incidence of neuro-ophthalmic complications. PMR is an inflammatory disease characterized by abrupt-onset pain and stiffness of the shoulder and pelvic girdle muscles. Both conditions are associated with a systemic inflammatory response and constitutional symptoms. The pathogeneses are unclear. The initiating step may be the recognition of an infectious agent by activated dendritic cells. The key cell type involved is CD4(+) T cells and the key cytokines are IFN-γ (implicated in granuloma formation) and IL-6 (key to the systemic response). The pathogenesis of PMR may be similar to that of GCA, however, PMR exhibits less clinical vascular involvement. The mainstay of therapy is corticosteroids, and disease-modifying therapy is indicated in relapsing disease. This article reviews recent guidelines on early recognition, investigations and management of these diseases, as well as advances in imaging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979556"}
{"pmid": "20979559", "title": "How genetic variation affects patient response and outcome to therapy for psoriasis.", "content": "How genetic variation affects patient response and outcome to therapy for psoriasis. Psoriasis is a prevalent chronic inflammatory condition that affects the skin. There are many treatments available for psoriasis but they are not universally effective and some have associated toxicities. Pharmacogenetics and pharmacogenomics explore the relationship between individual genetic variation and drug effect to allow targeted 'personalized' therapy for patients. There has been very limited pharmacogenetic research regarding psoriasis, with most limited to small retrospective case-control studies looking at single-nucleotide polymorphisms in candidate genes involved in drug pharmacokinetics. We review the pharmacogenetic investigation of treatments for psoriasis to date, including emerging pharmacogenomic studies. In addition, we discuss how such genetic data could be incorporated into routine clinical practice and future areas for development in this field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979559"}
{"pmid": "20979557", "title": "Recent advances in the treatment of eosinophilic esophagitis.", "content": "Recent advances in the treatment of eosinophilic esophagitis. First described nearly 20 years ago, eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus characterized by eosinophilic infiltration of the esophageal epithelium. Over 50% of the current literature on EoE has been published in the last 3 years, signaling both a rising incidence and increased recognition of this disorder. Treatment options available for patients with EoE include dietary management and/or pharmacologic therapy. An individualized approach to treatment is preferred, with an emphasis on patient-parental preference. The objective of this article is to discuss the current and future treatment options for EoE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979557"}
{"pmid": "20979561", "title": "Global DNA methylation: comparison of enzymatic- and non-enzymatic-based methods.", "content": "Global DNA methylation: comparison of enzymatic- and non-enzymatic-based methods. The most frequently used methods for measuring global DNA methylation are based on two different principles: the use of methylation-sensitive restriction endonucleases followed by analysis of the obtained fragments, or the hydrolysis of genomic DNA followed by specific detection and quantification of the 5-methylcytosine content. We aimed to compare two different methods for evaluation of global DNA methylation: the cytosine extension assay after enzymatic digestion of DNA (Cyt-Ext), and a recently described method using liquid chromatography-electrospray ionization-tandem mass spectrometry after DNA hydrolysis (LC-MS/MS). Both approaches were applied to evaluate global DNA methylation in leukocyte DNA from 96 healthy subjects. Calf thymus and pBR322 DNAs were used as hyper- and hypo-methylated references, respectively. Using the Cyt-Ext method, the DNA from healthy individuals showed radiolabel incorporation of 11,312±1600 Dpm/μg DNA, while the LC-MS/MS method showed 4.55±0.1% methylation. Results are shown as mean±SD. The analysis of hypo- and hyper-methylated references showed that both methods are practical for discriminating different levels of methylation. Cyt-Ext and LC-MS/MS are viable methods in evaluating global DNA methylation status. However, the LC-MS/MS assay allows absolute quantification and displays far superior intra-day precision. Therefore, we consider the later approach to be better for use in global DNA methylation studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979561"}
{"pmid": "20979562", "title": "Changes in parental weight and smoking habits and offspring adiposity: data from the HUNT-study.", "content": "Changes in parental weight and smoking habits and offspring adiposity: data from the HUNT-study. Adverse parental life-style habits are associated with offspring adiposity, but it is unclear how changes in these habits affect offspring adiposity. Thus, the aim of this study was to assess how parental change in body weight, smoking habits and levels of physical activity were associated with adiposity in their children. The study population consisted of 3 681 adolescents and their parents from the Nord-Trøndelag-Health-Study (HUNT). The parents participated in the two first waves of HUNT (HUNT-1:1984-86, HUNT-2:1995-97), where information on anthropometry, smoking habits and physical activity were obtained. The adolescents participated in the Youth-Part of HUNT-2. We used logistic regression to calculate odds-ratios (ORs) for adolescent offspring overweight according to parental change in body-weight, smoking habits and physical activity, adjusting for these factors in both parents, as well as for socioeconomic status and adolescent age and sex. Children of parents who changed weight from normal weight to overweight from HUNT-1 to HUNT-2 had higher OR for overweight in adolescence than children of parents who remained normal weight (mothers: 1.9 [95% CI: 1.4,2.5], fathers: 2.2 [95% CI: 1.5,3.0]). Children of mothers who reduced their weight from overweight to normal weight had no higher OR for overweight in adolescence than mothers who remained normal weight (OR: 1.0; 95% CI: 0.2, 4.7). Children of mothers who quit smoking (OR: 0.5; 95% CI: 0.3, 0.8) had lower OR for overweight in adolescence than children of mothers who persisted in smoking. Healthy changes in parental life-style during childhood are associated with lower occurrence of offspring overweight in adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979562"}
{"pmid": "20979558", "title": "An update on the use of NOD mice to study autoimmune (Type 1) diabetes.", "content": "An update on the use of NOD mice to study autoimmune (Type 1) diabetes. The widely used nonobese diabetic (NOD) mouse model of autoimmune (Type 1) diabetes mellitus shares multiple characteristics with the human disease, and studies employing this model continue to yield clinically relevant and important information. Here, we review some of the recent key findings obtained from NOD mouse investigations that have both advanced our understanding of disease pathogenesis and suggested new therapeutic targets and approaches. Areas discussed include antigen discovery, identification of genes and pathways contributing to disease susceptibility, development of strategies to image islet inflammation and the testing of therapeutics. We also review recent technical advances that, combined with an improved understanding of the NOD mouse model's limitations, should work to ensure its popularity, utility and relevance in the years ahead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979558"}
{"pmid": "20979563", "title": "MDM2 and CDKN1A gene polymorphisms and risk of Kaposi's sarcoma in African and Caucasian patients.", "content": "MDM2 and CDKN1A gene polymorphisms and risk of Kaposi's sarcoma in African and Caucasian patients. A single-nucleotide polymorphism in the MDM2 promoter (SNP309; rs2279744) causes elevated transcription of this major negative regulator of p53 in several cancer types. We investigated MDM2 SNP309 and CDKN1A (p21/Waf1/Cip1) codon 31 (rs1801270) polymorphisms in 86 cases of cutaneous Kaposi's sarcoma (KS) from African and Caucasian patients, and 210 healthy controls. A significant increase of the MDM2 SNP309 T/G genotype was observed among classic KS cases (odds ratio 2.38, 95% confidence interval 1.0-5.5). Frequencies of CDKN1A codon 31 genotypes were not significantly different between cases and controls. The results suggest that the MDM2 SNP309 G allele may act as a susceptibility gene for the development of classic KS in Caucasian patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979563"}
{"pmid": "20979564", "title": "The efficacy and safety of interleukin-1-receptor antagonist anakinra in the treatment of systemic juvenile idiopathic arthritis.", "content": "The efficacy and safety of interleukin-1-receptor antagonist anakinra in the treatment of systemic juvenile idiopathic arthritis. Systemic juvenile idiopathic arthritis (sJIA) is a debilitating childhood disease presenting with fever, rash and arthritis. Current therapy consisting mainly of corticosteroids, NSAIDs and methotrexate, can be inefficient and is often accompanied by many serious adverse events. Although an IL-1 receptor antagonist (anakinra) seems to be very efficient in case series, it is not registered for use in sJIA. Pediatric rheumatologists all over the world are having a hard time to convince insurance companies to approve off-label use of this drug for their sJIA patients. Using the MeSH terms 'Arthritis Juvenile Rheumatoid' and 'Interleukin 1 Receptor Antagonist Protein', we searched MEDLINE, EMBASE and reference lists of selected articles. This review is largely based on manuscripts from 2005 to 2010 and abstracts presented at the major (pediatric) rheumatology congresses. This review summarizes the data of 140 children with sJIA treated with anakinra and enables an understanding in the benefit-risk profile of anakinra in sJIA patients. Anakinra has shown to be a very efficient and quick acting medicine in reducing symptoms even in therapy-resistant sJIA patients with typically poor outcomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979564"}
{"pmid": "20979565", "title": "Population structure of Aggarwals of north India as revealed by molecular markers.", "content": "Population structure of Aggarwals of north India as revealed by molecular markers. Using molecular genetic data on Aggarwals (Vaish/Vysya), an endogamous population group of north India, we provide evidence of its homogeneous unstratified population structure. We found the mean average heterozygosity value of 0.33 for 14 single nucleotide polymorphisms belonging to four genes (TCF7L2-, HHEX-, KCNJ11-, and ADIPOQ-) in the Aggarwal population (sample of 184 individuals) and tried to evaluate the genomic efficiency of endogamy in this population with the help of clan-based stratified analysis. We concluded that the sociocultural identity of the endogamous population groups could act as a robust proxy maker for inferring their homogeneity and population structure in India, which is ideal also for population selection for future genome-wide association studies in the country.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979565"}
{"pmid": "20979566", "title": "Health-care referrals from direct-to-consumer genetic testing.", "content": "Health-care referrals from direct-to-consumer genetic testing. direct-to-consumer genetic testing (DTC-GT) provides personalized genetic risk information directly to consumers. Little is known about how and why consumers then communicate the results of this testing to health-care professionals. to query specialists in clinical genetics about their experience with individuals who consulted them after DTC-GT. invitations to participate in a questionnaire were sent to three different groups of genetic professionals, totaling 4047 invitations, asking questions about individuals who consulted them after DTC-GT. For each case reported, respondents were asked to describe how the case was referred to them, the patient's rationale for DTC-GT, and the type of DTC-GT performed. Respondents were also queried about the consequences of the consultations in terms of additional testing ordered. The costs associated with each consultation were estimated. A clinical case series was compiled based upon clinician responses. the invitation resulted in 133 responses describing 22 cases of clinical interactions following DTC-GT. Most consultations (59.1%) were self-referred to genetics professionals, but 31.8% were physician referred. Among respondents, 52.3% deemed the DTC-GT to be \"clinically useful.\" BRCA1/2 testing was considered clinically useful in 85.7% of cases; 35.7% of other tests were considered clinically useful. Subsequent referrals from genetics professionals to specialists and/or additional diagnostic testing were common, generating individual downstream costs estimated to range from $40 to $20,600. this clinical case series suggests that approximately half of clinical geneticists who saw patients after DTC-GT judged that testing was clinically useful, especially the BRCA1/2 testing. Further studies are needed in larger and more diverse populations to better understand the interactions between DTC-GT and the health-care system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979566"}
{"pmid": "20979567", "title": "Personalized cancer vaccines.", "content": "Personalized cancer vaccines. Personalized medicine has extended to management of cancer and implies prescription of specific therapeutics best suited for an individual patient and the type of tumor. These principles have been applied to cancer vaccines. Various cancer vaccines that can be personalized. Tumor-derived vaccines have been used and active immunotherapy based on antigens specific to the tumor. Dendritic cells (DCs) can prime tumor-specific T cell responses and are considered potentially effective vaccines for cancer. DCs may be genetically modified or fused with tumor cells. Adoptive cell therapy is based on autologous antigen-specific T lymphocytes. Personalized peptide vaccination has been combined with chemotherapy. Clinical trials have been conducted. There have been many failures but a selection of those currently in progress is presented. An overview of various types of personalized cancer vaccines, their mechanism of action and current status of development. Causes of failure of clinical trials and concepts of an ideal personalized cancer vaccine are presented. A number of approaches are available for personalized cancer vaccines with variable degree of success. There are several challenges and needs for refinement of methods but it remains a promising area of cancer therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979567"}
{"pmid": "20979568", "title": "Decompressive craniectomy for severe head injury: does an outcome prediction model influence clinical decision-making?", "content": "Decompressive craniectomy for severe head injury: does an outcome prediction model influence clinical decision-making? The use of a prognostic model to aid clinician decision-making with regard to decompressive craniectomy for patients with severe neurotrauma has not been examined. Thus in this study we assessed whether an internationally validated prediction model would influence clinician decision-making about craniectomy. A two-part structured interview, given before and after knowing the predicted risks of unfavorable neurological outcomes at 6 months, was used to assess the participants' recommendations about performing decompressive craniectomy in three patients with severe traumatic brain injury. The participants rated their preferences when there was no surrogate decision maker available, when the next of kin requested surgical intervention, when the patient had an advance directive, and when the participant was the injured party. A visual analogue scale (1-10) was used to assess the strength of their opinions. A total of 50 neurosurgeons and intensive care physicians participated in this study. The participants were significantly more likely to recommend decompressive craniectomy for their patients than for themselves, especially when the next of kin of the patient demanded the procedure, and were more similar in their own preferences to patients who had advance directives. Clinicians' preferences to perform the procedure for both themselves and their patients was significantly reduced after knowing the predicted risks of unfavorable outcomes, and these changes in attitude were consistent across those with different specialties, regardless of the amount of experience caring for similar patients, or religious background. In conclusion, the predicted risks of unfavorable outcomes influenced clinician decision-making about recommending decompressive craniectomy for patients with very severe neurotrauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979568"}
{"pmid": "20979569", "title": "Clinical evolution of substance use disorder patients during treatment with quetiapine: a 12-week, open-label, naturalistic trial.", "content": "Clinical evolution of substance use disorder patients during treatment with quetiapine: a 12-week, open-label, naturalistic trial. Substance use disorders (SUDs) are associated with a variety of psychiatric disorders and mood and behavioral instability. Growing evidence suggests that the atypical antipsychotic quetiapine may be useful in the treatment of SUDs. The primary objective of the current open-label trial was to examine the effects of quetiapine on SUD outcomes in patients entering detoxification. Thirty-three nonpsychosis SUD patients participated. Patients received quetiapine for a 12-week beginning in detoxification. Craving, quantities used and psychiatric symptoms were evaluated on baseline and at end point. Out of 33 recruited patients, 26 completed > 9 weeks of treatment. Last observation carried forward (LOCF) analyses revealed that craving, SUD severity and quantities used improved during the study. Psychiatric and depressive symptoms also improved. Our results cannot be attributed per se to the pharmacological effects of quetiapine owing to the open-label design of the study, the small sample size involved and the fact that patients were involved in an intensive therapy program. Nevertheless, our results indicate that quetiapine may be helpful for the treatment of SUD patients entering detoxification. Controlled studies are warranted to determine whether these results are quetiapine-related.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979569"}
{"pmid": "20979570", "title": "Inhibiting PAR-1 in the prevention and treatment of atherothrombotic events.", "content": "Inhibiting PAR-1 in the prevention and treatment of atherothrombotic events. Aspirin, an irreversible inhibitor of thromboxane A(2) production, in combination with clopidogrel, an inhibitor of PY(12) ADP platelet receptors, represents the current standard-of-care of antiplatelet therapy for patients with acute coronary syndrome and those undergoing percutaneous coronary intervention. Although these agents have demonstrated significant clinical benefit, the increased risk of bleeding and the recurrence of thrombotic events represent substantial limitations. The inhibition of protease-activated receptors (PAR)-1, is the target for novel antiplatelet drugs, which showed a good safety profile in preclinical studies. The drugs most developed are vorapaxar (SCH530348) and atopaxar (E5555), which will be further evaluated in ongoing Phase III and II clinical trials respectively. This review is focused on the current knowledge of PAR-1 antagonists, analyzing the pharmacological and early phase clinical investigation findings on these new drugs. The PAR-1 receptor offers a new target for the inhibition of platelet activation and aggregation. Preliminary results showed the good safety profile of these new agents. The results of the Phase III ongoing trials will provide important clinical insight into the blockade of thrombin-induced platelet activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979570"}
{"pmid": "20979571", "title": "Roles for lysophospholipid S1P receptors in multiple sclerosis.", "content": "Roles for lysophospholipid S1P receptors in multiple sclerosis. Sphingosine 1-phosphate (S1P) signaling in the treatment of multiple sclerosis (MS) has been highlighted by the efficacy of FTY720 (fingolimod), which upon phosphorylation can modulate S1P receptor activities. FTY720 has become the first oral treatment for relapsing MS that was approved by the FDA in September 2010. Phosphorylated FTY720 modulates four of the five known S1P receptors (S1P(1), S1P(3), S1P(4), and S1P(5)) at high affinity. Studies in human MS and its animal model, experimental autoimmune encephalomyelitis (EAE), have revealed that FTY720 exposure alters lymphocyte trafficking via sequestration of auto-aggressive lymphocytes within lymphoid organs, representing the current understanding of its mechanism of action. These effects primarily involve S1P(1), which is thought to attenuate inflammatory insults in the central nervous system (CNS). In addition, FTY720's actions may involve direct effects on S1P receptor-mediated signaling in CNS cells, based upon the known expression of S1P receptors in CNS cell types relevant to MS, access to the CNS through the blood-brain barrier (BBB), and in vitro studies. These data implicate lysophospholipid signaling--via S1P(1) and perhaps other lysophospholipid receptors--in therapeutic approaches to MS and potentially other diseases with immunological and/or neurological components.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979571"}
{"pmid": "20979573", "title": "Lisdexamfetamine dimesylate: a new option in stimulant treatment for ADHD.", "content": "Lisdexamfetamine dimesylate: a new option in stimulant treatment for ADHD. Attention deficit/hyperactivity disorder (ADHD), a prevalent disorder in children and adults, presents a substantial societal burden in both monetary cost and human suffering. Characterized by significant difficulties in maintaining attention, completing tasks, motor control, and appropriate social engagement, the disorder begins early in life and results in significant impairment across domains of functioning, including social, educational, and occupational achievement. The condition also carries heightened risk of substance use and dependence, and criminal activity. Pharmacologic treatment is a key component of ADHD management and has been found to be cost effective and generally well tolerated. However, despite increasing options for medication therapy, community management of ADHD is suboptimal. This review assesses current research on lisdexamfetamine dimesylate (LDX), a relatively recent addition to the range of treatment options. This review summarizes peer-reviewed literature on LDX published 2003 - 2010. The reader will gain insight into the efficacy and safety of LDX in the treatment of ADHD, and its place in the clinical armamentarium. LDX is a useful addition to the formulary, showing similar efficacy and safety profiles to other stimulants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979573"}
{"pmid": "20979574", "title": "Hereditary hemochromatosis: awareness and genetic testing acceptability in Western Romania.", "content": "Hereditary hemochromatosis: awareness and genetic testing acceptability in Western Romania. a public health strategy to promote early diagnosis of hemochromatosis gene (HFE)-related hemochromatosis (HFE-HH) largely depends on people's acceptance of available screening tests. The present study aimed at evaluating patient awareness of HFE-HH and their acceptance of DNA testing in western Romania. a total of 221 participants were randomly recruited from the ambulatory unit of the Emergency County Hospital in Timisoara, Romania. They received brief information on HFE-HH and were assessed for the signs and symptoms of hemochromatosis. HFE genotyping was offered to all of them. Only two cases (0.9%) had previous knowledge of HFE-HH. Twenty-one cases (9.5%) underwent genetic testing. Characteristics associated with test acceptance were age <45 years, male gender, and educational attainment. Acceptance was associated with a desire to know if they had HFE-HH (85.7%). The most prevalent refusal reason was a desire for more information (41%). larger educational programs are required to increase people's awareness about HFE-HH in western Romania. Nevertheless, within health care settings, the importance of disease detection and patient's educational background appear to be essential for achieving high rates of participation in the genetic test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979574"}
{"pmid": "20979572", "title": "Is the association of breastfeeding with child obesity explained by infant weight change?", "content": "Is the association of breastfeeding with child obesity explained by infant weight change? Breastfeeding and infant weight change are both associated with adiposity. We examined the extent to which infant weight change mediates the association between breastfeeding and adiposity at age 3 years. We studied 884 children in a prospective cohort study. We determined breastfeeding status in the first 6 months. Our primary outcomes at 3 years were body mass index (BMI) z score and the sum of subscapular and triceps skinfold thicknesses (SS + TR); we also assessed obesity. We defined infant weight change as change in weight-for-age z score between birth and 6 months. We performed multivariable regression analyses. At age 6 months, 25.0% of infants were fully breastfed. At age 3 years, mean (standard deviation) BMI z score was 0.45 (1.03). In linear regression analyses adjusted for mother's educational level, race/ethnicity, smoking, BMI, pregnancy weight gain and birth weight (adjusted for gestational age), the BMI z score of fully breastfed children was 0.17 (95% CI: -0.43, 0.09) units lower than never breastfed children. After additional adjustment for infant weight change, the estimate was attenuated (-0.03, 95% CI: -0.27, 0.20). Adjustment for infant weight change only modestly attenuated estimates for SS + TR (from -1.48 mm [95% CI: -2.52, -0.44] to -1.16 mm [95% CI: -2.18, -0.14]), and for the odds of being obese (from 0.21 [95% CI: 0.07, 0.68] to 0.29 [95% CI: 0.08, 1.05]). Infant weight change between birth and 6 months mediates associations of breastfeeding with BMI, but only partially with indicators of child adiposity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979572"}
{"pmid": "20979575", "title": "Dysfunction of human subcutaneous fat arterioles in obesity alone or obesity associated with Type 2 diabetes.", "content": "Dysfunction of human subcutaneous fat arterioles in obesity alone or obesity associated with Type 2 diabetes. The aim of the present study was to examine the effects of obesity alone and obesity associated with Type 2 diabetes on the structure, vascular reactivity and response to insulin of isolated human subcutaneous fat arterioles; these effects were correlated with the expression of insulin signalling proteins. Periumbilical subcutaneous adipose tissue was explanted during surgery, small arterioles (internal diameter 220 ± 40 μm) were dissected out and investigated by electron microscopy, myography and immunoblotting. Compared with the subcutaneous arterioles of lean subjects, obesity activated the endothelium, enhanced the accumulation of collagen within vascular wall and increased the sensitivity of adrenergic response; obesity also diminished eNOS (endothelial NO synthase) protein expression, NO production, and endothelium-dependent and insulin-induced vasodilatation, as well as the protein expression of both IRS (insulin receptor substrates)-1 and IRS-2 and of the downstream molecules in the insulin signalling pathway, such as PI3K (phosphoinositide 3-kinase), phospho-Akt and Akt. When obesity was associated with Type 2 diabetes, these changes were significantly augmented. In conclusion, obesity alone or obesity associated with Type 2 diabetes alters human periumbilical adipose tissue arterioles in terms of structure, function and biochemsitry, including diminished eNOS expression and reduced levels of IRS-1, IRS-2, PI3K and Akt in the insulin signalling pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979575"}
{"pmid": "20979576", "title": "Identification of binding partners interacting with the α1-N-propeptide of type V collagen.", "content": "Identification of binding partners interacting with the α1-N-propeptide of type V collagen. The predominant form of type V collagen is the [α1(V)]₂α2(V) heterotrimer. Mutations in COL5A1 or COL5A2, encoding respectively the α1(V)- and α2(V)-collagen chain, cause classic EDS (Ehlers-Danlos syndrome), a heritable connective tissue disorder, characterized by fragile hyperextensible skin and joint hypermobility. Approximately half of the classic EDS cases remain unexplained. Type V collagen controls collagen fibrillogenesis through its conserved α1(V)-N-propeptide domain. To gain an insight into the role of this domain, a yeast two-hybrid screen among proteins expressed in human dermal fibroblasts was performed utilizing the N-propeptide as a bait. We identified 12 interacting proteins, including extracellular matrix proteins and proteins involved in collagen biosynthesis. Eleven interactions were confirmed by surface plasmon resonance and/or co-immunoprecipitation: α1(I)- and α2(I)-collagen chains, α1(VI)-, α2(VI)- and α3(VI)-collagen chains, tenascin-C, fibronectin, PCPE-1 (procollagen C-proteinase enhancer-1), TIMP-1 (tissue inhibitor of metalloproteinases-1), MMP-2 (matrix metalloproteinase 2) and TGF-β1 (transforming growth factor β1). Solid-phase binding assays confirmed the involvement of the α1(V)-N-propeptide in the interaction between native type V collagen and type VI collagen, suggesting a bridging function of this protein complex in the cell-matrix environment. Enzymatic studies showed that processing of the α1(V)-N-propeptide by BMP-1 (bone morphogenetic protein 1)/procollagen C-proteinase is enhanced by PCPE-1. These interactions are likely to be involved in extracellular matrix homoeostasis and their disruption could explain the pathogenetic mechanism in unresolved classic EDS cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979576"}
{"pmid": "20979579", "title": "PKCζ-interacting protein ZIP3 is generated by intronic polyadenylation, and is expressed in the brain and retina of the rat.", "content": "PKCζ-interacting protein ZIP3 is generated by intronic polyadenylation, and is expressed in the brain and retina of the rat. Scaffold proteins contain multiple protein-protein interaction modules that physically assemble functionally related proteins into larger complexes. ZIPs [PKC (protein kinase C) ζ-interacting proteins] link the enzymatic activity of the atypical PKC isoforms PKCλ/ι or PKCζ to target proteins and are associated with neurodegenerative disorders. In the rat, alternative splicing generates three ZIP variants. Previously, we identified the ZIP3 transcript, containing 13 C-terminal amino acids encoded by intron 4, in the rat CNS (central nervous system). In the present study, we identified intronic polyadenylation signals in rat and human ZIP genes [known as SQSTM1 (sequestosome-1) in humans] and detected the corresponding ZIP3-like transcripts. In addition, we generated ZIP3-specific immune sera and observed expression of the protein in the brain and retina of the adult rat. In the retina, ZIP3 is present in nuclear layers where it co-localizes with PKCζ. An immune serum recognizing all three ZIP isoforms labelled the same cells as the newly generated ZIP3-specific antibodies and, in addition, stained both synaptic layers of the retina. There, ZIPs are localized in axon terminals of rod bipolar cells that also contain ZIP-interacting PKCζ and GABA(C) (γ-aminobutyric acid type C) receptors. In summary, we detected ZIP3-like transcripts in rat- and human-derived samples and describe the expression of ZIP3 in the rat CNS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979579"}
{"pmid": "20979578", "title": "Notch1 and the activated NOTCH1 intracellular domain are expressed in differentiated trophoblast cells.", "content": "Notch1 and the activated NOTCH1 intracellular domain are expressed in differentiated trophoblast cells. The Notch signalling pathway regulates proliferation, cell death and cell type specification that is critical for organogenesis. Mouse models carrying mutations in the Notch signalling pathway display defects in development of the placenta, suggesting that this pathway is required for placental development. In particular, Notch1 mutant embryos exhibit abnormal placental morphogenesis and arrest early in development. However, expression of Notch1 gene has not been detected during placental development. Trophoblast stem cells are derived from the precursor of the placenta and express Notch1. We report that Notch1 is also expressed in differentiated trophoblast cells. Under standard differentiation conditions, Notch1 expression ceases by day 6. Furthermore, the activated NOTCH1 intracellular domain is enriched at the nucleolus of trophoblast stem cells and differentiated trophoblast cells. Our results suggest that NOTCH1 is active in both trophoblast stem cells and differentiated trophoblast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979578"}
{"pmid": "20979577", "title": "Effects of extracellular environment factors on the motility in Japanese eel spermatozoa.", "content": "Effects of extracellular environment factors on the motility in Japanese eel spermatozoa. We have examined the effects in vitro of the ionic composition, pH and temperature on the motility by the spermatozoa of the Japanese eel (Anguilla japonica). Milt was obtained from 10 males that had been artificially matured by repeated injections of hCG. Sperm motility was monitored with a VHS video recorder and a video camera connected to a microscope. The results showed that most of the sperm were highly motile in 250-700 mM NaCl, 250-650 mM KCl and 350-550 mM CaCl2 solution. The longest duration of sperm motility recorded in 500 mM NaCl, 250 mM KCl and 350 mM CaCl2 solution. Sperm was not motile when suspended at pH 2, sperm motility was observed at pH 3, there was a relatively higher percentage of motile sperm in solutions at pH 4-12 (above 80%). The motility and duration increased within 18-24°C and decreased at the range of 24-30°C. Appropriate K+ ion concentration in the active medium could enhance the percent motility and duration of eel spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979577"}
{"pmid": "20979580", "title": "Production of recombinant Bombyx mori nucleopolyhedrovirus in silkworm by intrahaemocoelic injection with invasive diaminopimelate auxotrophic Escherichia coli containing BmNPV-Bacmid.", "content": "Production of recombinant Bombyx mori nucleopolyhedrovirus in silkworm by intrahaemocoelic injection with invasive diaminopimelate auxotrophic Escherichia coli containing BmNPV-Bacmid. The present study elaborates a cost-effective and transfectant-free method for generating recombinant Bombyx mori (silkworm) nucleopolyhedrovirus in silkworm larvae and pupae by injecting invasive Escherichia coli carrying BmBacmid [BmNPV (B. mori nucleopolyhedrovirus)-Bacmid] into larval haemocoel. Up to 109 PFU (plaque-forming units)/ml of infective recombinant baculovirus was generated in the silkworm by intrahaemocoelic injection with 106 DAP (diaminopimelic acid) auxotrophic and BmBacmid containing E. coli cells expressing both invasin and listeriolysin. Thus 1 ml of overnight culture of E. coli is sufficient to inject more than 2000 larvae, while DAP costing up to $1 is enough to inject about 4000 larvae. Recombinant proteins can be controlled to be expressed mainly in pupae by adjusting the injection dose, too. In this new method, many original manipulations have been eliminated, including BmBacmid preparation and the subsequent complex transfection procedures. Hence it is a time- and cost-saving means for large-scale injection of B. mori for recombinant baculovirus production in comparison with the traditional transfection methods, which may play an important role in the industrial development of the BmNPV-silkworm bioreactor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979580"}
{"pmid": "20979581", "title": "Meta-analysis of the cardiovascular benefits of intensive lipid lowering with statins.", "content": "Meta-analysis of the cardiovascular benefits of intensive lipid lowering with statins. To evaluate the efficacy of intensive lipid lowering with higher-dose statins. Meta-analysis of seven randomized controlled trials comprising 50,972 participants. Mean follow-up was 3.1 years with mean age 63 years. Final LDL-C levels in intensive lipid-lowering group were 1.42-2.07 mmol/l compared to 2.1-3.5 mmol/l in the less intensive or control group. The intensive arm had significantly lower risks for stroke OR 0.80 (95% CI 0.71-0.89); major coronary events OR 0.74 (95% CI 0.65-0.83); cardiovascular disease (CVD) or coronary heart disease (CHD) deaths OR 0.84 (95% CI 0.74-0.95). Significantly higher liver enzyme abnormalities occurred in intensive group* (OR 3.96; 95% CI 2.08-7.53), but it was not associated with drug discontinuations (OR 1.20; 95% CI 0.88-1.64). In those at high risk of cardiovascular events, intensive lipid lowering with statins to LDL-C level <2.1 mmol/l significantly reduces risk of stroke, major coronary events and CVD or CHD deaths compared to LDL-C level ≥ 2.1 mmol/l. [*Correction added on 11 January 2011 after first online publication on 27 October 2010. The phrase, \"Significantly higher liver enzyme abnormalities occurred in less intensive group\", was amended to \"Significantly higher liver enzyme abnormalities occurred in intensive group\".].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979581"}
{"pmid": "20979582", "title": "Renewed focus on the developing human neocortex.", "content": "Renewed focus on the developing human neocortex. Many specifically human psychiatric and neurological conditions have developmental origins. Rodent models are extremely valuable for the investigation of brain development, but cannot provide insight into aspects that are specifically human. The human brain, and particularly the cerebral cortex, has some unique genetic, molecular, cellular and anatomical features, and these need to be further explored. Cortical expansion in human is not just quantitative; there are some novel types of neurons and cytoarchitectonic areas identified by their gene expression, connectivity and functions that do not exist in rodents. Recent research into human brain development has revealed more elaborated neurogenetic compartments, radial and tangential migration, transient cell layers in the subplate, and a greater diversity of early-generated neurons, including predecessor neurons. Recently there has been a renaissance of the study of human brain development because of these unique differences, made possible by the availability of new techniques. This review gives a flavour of the recent studies stemming from this renewed focus on the developing human brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979582"}
{"pmid": "20979584", "title": "Abnormal development of the human cerebral cortex.", "content": "Abnormal development of the human cerebral cortex. This review presents an overview of human cortical malformation based on the insights gained from examination of human fetal brains. Examination at early stages of fetal brain development allows the identification of the specific pathways which are disrupted in human cortical malformation. Detailed examination of human fetal brains in parallel with studies of genetics and animal models is leading to new concepts of cortical malformations. Here we review a range of human cortical malformations based on a simple classification according to the developmental process thought to be disrupted: neuroblast proliferation, undermigration, overmigration, cortical maturation and destructive lesions. A single case example of a dated intrauterine injury illustrates the spectrum of malformations which may result at a single period in development. The recommended methods of examination of human fetal brain are described together with some of their pitfalls. Detailed neuropathological observations indicate the need for caution in the classification of malformations; radiological findings and pathology of the mature brain do not reflect the specific disruptive pathways of cortical malformations. While many insults may lead to the same pattern of malformation, a single insult can lead to multiple patterns of malformation. Our detailed studies of the human fetal brain suggest that the interface between the meninges and the radial glial end feet may be an intriguing new focus of interest in understanding cortical development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979584"}
{"pmid": "20979583", "title": "The HUDSEN Atlas: a three-dimensional (3D) spatial framework for studying gene expression in the developing human brain.", "content": "The HUDSEN Atlas: a three-dimensional (3D) spatial framework for studying gene expression in the developing human brain. We are developing a three-dimensional (3D) atlas of the human embryonic brain using anatomical landmarks and gene expression data to define major subdivisions through 12 stages of development [Carnegie Stages (CS) 12-23; approximately 26-56 days post conception (dpc)]. Virtual 3D anatomical models are generated from intact specimens using optical projection tomography (OPT). Using MAPAINT software, selected gene expression data, gathered using standard methods of in situ hybridization and immunohistochemistry, are mapped to a representative 3D model for each chosen Carnegie stage. In these models, anatomical domains, defined on the basis of morphological landmarks and comparative knowledge of expression patterns in vertebrates, are linked to a developmental neuroanatomic ontology. Human gene expression patterns for genes with characteristic expression in different vertebrates (e.g. PAX6, GAD65 and OLIG2) are being used to confirm and/or refine the human anatomical domain boundaries. We have also developed interpolation software that digitally generates a full domain from partial data. Currently, the 3D models and a preliminary set of anatomical domains and ontology are available on the atlas pages along with gene expression data from approximately 100 genes in the HUDSEN Human Spatial Gene Expression Database (http://www.hudsen.org). The aim is that full 3D data will be generated from expression data used to define a more detailed set of anatomical domains linked to a more advanced anatomy ontology and all of these will be available online, contributing to the long-term goal of the atlas, which is to help maximize the effective use and dissemination of data wherever it is generated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979583"}
{"pmid": "20979585", "title": "Early history of subplate and interstitial neurons: from Theodor Meynert (1867) to the discovery of the subplate zone (1974).", "content": "Early history of subplate and interstitial neurons: from Theodor Meynert (1867) to the discovery of the subplate zone (1974). In this historical review, we trace the early history of research on the fetal subplate zone, subplate neurons and interstitial neurons in the white matter of the adult nervous system. We arrive at several general conclusions. First, a century of research clearly testifies that interstitial neurons, subplate neurons and the subplate zone were first observed and variously described in the human brain - or, in more general terms, in large brains of gyrencephalic mammals, characterized by an abundant white matter and slow and protracted prenatal and postnatal development. Secondly, the subplate zone cannot be meaningfully defined using a single criterion - be it a specific population of cells, fibres or a specific molecular or genetic marker. The subplate zone is a highly dynamic architectonic compartment and its size and cellular composition do not remain constant during development. Thirdly, it is important to make a clear distinction between the subplate zone and the subplate (and interstitial) neurons. The transient existence of the subplate zone (as a specific architectonic compartment of the fetal telencephalic wall) should not be equated with the putative transient existence of subplate neurons. It is clear that in rodents, and to an even greater extent in humans and monkeys, a significant number of subplate cells survive and remain functional throughout life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979585"}
{"pmid": "20979589", "title": "Aortic arch morphometry in living humans.", "content": "Aortic arch morphometry in living humans. Anatomical features of the aortic arch such as its steepness, the take-off angles and the distances between its supra-aortic branches can influence the feasibility and difficulty of interventional and/or surgical maneuvers. These anatomical characteristics were assessed by means of 3D multiplanar reconstruction of thoracic angio-computed tomography scans of 92 living patients (79 males, 13 females, mean age 69.4 ± 9.9 years) carried out for various indications (gross pathology of the thoracic aorta excluded). There was a significant variation of all measured parameters between the subjects - a standard aortic arch (i.e. with all measured parameters within 2 SD) does not seem to exist. There were no significant differences between genders but some of the parameters correlated significantly to age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979589"}
{"pmid": "20979588", "title": "Development of the cornea of true moles (Talpidae): morphogenesis and expression of PAX6 and cytokeratins.", "content": "Development of the cornea of true moles (Talpidae): morphogenesis and expression of PAX6 and cytokeratins. Corneal development and structure were studied in the Iberian mole Talpa occidentalis, which has permanently closed eyelids, and the European mole Talpa europaea, in which the eyes are open. The vertebrate cornea typically maintains a three-layered structure - a stratified epithelium with protective and sensory function, an avascular, hypocellular, collagenous stroma, and an endothelium with both barrier and transport functions that regulates corneal hydration, hence maintaining transparency. Compared to mouse, both mole species had significant corneal specializations, but the Iberian mole had the most divergent phenotype, with no endothelium and a flattened monolayer epithelium. Nevertheless, normal epithelial cell junctions were observed and corneal transparency was maintained. Corneas of European moles have a dysmorphic phenotype that recapitulates the human disorder keratoconus for which no mouse model exists. Mole corneas are vascularized - a situation only previously observed in the manatee Trichechus- and have non-radial patterns of corneal innervation indicative of failure of corneal epithelial cell migration. The transcription factor Pax6 is required for corneal epithelial differentiation in mice, but was found to be dispensable in moles, which had mosaic patterns of PAX6 localization uniquely restricted, in European moles, to the apical epithelial cells. The apparently stalled or abnormal differentiation of corneas in adult moles is supported by their superficial similarity to the corneas of embryonic or neonatal mice, and their abnormal expression of cytokeratin-12 and cytokeratin-5. European moles seem to have maintained some barrier/protective function in their corneas. However, Iberian moles show a more significant corneal regression likely related to the permanent eyelid fusion. In this mole species, adaptation to the arid, harder, Southern European soils could have favoured the transfer of these functions to the permanently sealed eyelids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979588"}
{"pmid": "20979586", "title": "Populations of subplate and interstitial neurons in fetal and adult human telencephalon.", "content": "Populations of subplate and interstitial neurons in fetal and adult human telencephalon. In the adult human telencephalon, subcortical (gyral) white matter contains a special population of interstitial neurons considered to be surviving descendants of fetal subplate neurons [Kostovic & Rakic (1980) Cytology and the time of origin of interstitial neurons in the white matter in infant and adult human and monkey telencephalon. J Neurocytol9, 219]. We designate this population of cells as superficial (gyral) interstitial neurons and describe their morphology and distribution in the postnatal and adult human cerebrum. Human fetal subplate neurons cannot be regarded as interstitial, because the subplate zone is an essential part of the fetal cortex, the major site of synaptogenesis and the 'waiting' compartment for growing cortical afferents, and contains both projection neurons and interneurons with distinct input-output connectivity. However, although the subplate zone is a transient fetal structure, many subplate neurons survive postnatally as superficial (gyral) interstitial neurons. The fetal white matter is represented by the intermediate zone and well-defined deep periventricular tracts of growing axons, such as the corpus callosum, anterior commissure, internal and external capsule, and the fountainhead of the corona radiata. These tracts gradually occupy the territory of transient fetal subventricular and ventricular zones.The human fetal white matter also contains distinct populations of deep fetal interstitial neurons, which, by virtue of their location, morphology, molecular phenotypes and advanced level of dendritic maturation, remain distinct from subplate neurons and neurons in adjacent structures (e.g. basal ganglia, basal forebrain). We describe the morphological, histochemical (nicotinamide-adenine dinucleotide phosphate-diaphorase) and immunocytochemical (neuron-specific nuclear protein, microtubule-associated protein-2, calbindin, calretinin, neuropeptide Y) features of both deep fetal interstitial neurons and deep (periventricular) interstitial neurons in the postnatal and adult deep cerebral white matter (i.e. corpus callosum, anterior commissure, internal and external capsule and the corona radiata/centrum semiovale). Although these deep interstitial neurons are poorly developed or absent in the brains of rodents, they represent a prominent feature of the significantly enlarged white matter of human and non-human primate brains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979586"}
{"pmid": "20979587", "title": "Neuroimaging of cortical development and brain connectivity in human newborns and animal models.", "content": "Neuroimaging of cortical development and brain connectivity in human newborns and animal models. Significant human brain growth occurs during the third trimester, with a doubling of whole brain volume and a fourfold increase of cortical gray matter volume. This is also the time period during which cortical folding and gyrification take place. Conditions such as intrauterine growth restriction, prematurity and cerebral white matter injury have been shown to affect brain growth including specific structures such as the hippocampus, with subsequent potentially permanent functional consequences. The use of 3D magnetic resonance imaging (MRI) and dedicated postprocessing tools to measure brain tissue volumes (cerebral cortical gray matter, white matter), surface and sulcation index can elucidate phenotypes associated with early behavior development. The use of diffusion tensor imaging can further help in assessing microstructural changes within the cerebral white matter and the establishment of brain connectivity. Finally, the use of functional MRI and resting-state functional MRI connectivity allows exploration of the impact of adverse conditions on functional brain connectivity in vivo. Results from studies using these methods have for the first time illustrated the structural impact of antenatal conditions and neonatal intensive care on the functional brain deficits observed after premature birth. In order to study the pathophysiology of these adverse conditions, MRI has also been used in conjunction with histology in animal models of injury in the immature brain. Understanding the histological substrate of brain injury seen on MRI provides new insights into the immature brain, mechanisms of injury and their imaging phenotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979587"}
{"pmid": "20979590", "title": "Conception rates in ewes after AI with ram semen preserved in milk-egg yolk extenders supplemented with glycerol.", "content": "Conception rates in ewes after AI with ram semen preserved in milk-egg yolk extenders supplemented with glycerol. This study aimed at comparing the effect of ram semen preserved at 5 °C on two milk-based extenders (UHT skim milk or INRA-96(®) , 5% egg yolk) supplemented with 2% glycerol, and the preservation time (24 and 48 h) on conception rates after cervical AI of ewes. In two field trials, 1198 Merino ewes were cervical AI in spontaneous oestrus. In Experiment 1, pooled semen (6 rams) was extended in UHT-base (fresh, control) or chilled for 24 h in UHT5Y (UHT-base 5% egg yolk), INRA5Y (INRA-96(®) 5% egg yolk), UHT5Y2G (UHT5Y 2% glycerol) or INRA5Y2G (INRA5Y 2% glycerol). In Experiment 2, AI was performed with pooled semen (7 rams) used fresh (extended in UHT-base or UHT5Y2G, control groups) or chilled (extended in UHT5Y2G) for 24 or 48 h. Conception rate was determined by ultrasound 40 days after AI. INRA-96(®) - had similar conception as UHT-preserved semen (56.7 vs 55.4%, p>0.05). Addition of 2% glycerol did not modify the results (56.8 vs 55.2%, p>0.05). Fresh semen extended in UHT-base, and UHT5Y2G yielded similar conception rates (60 vs 64%, p>0.05). Preservation for 24 or 48 h in UHT5Y2G gave similar results (49 vs 47%; p>0.05). In conclusion, ram semen chilled for 24 h in UHT- or INRA-96(®) -based extenders yielded similar results, and glycerol addition did not have a detrimental effect. UHT5Y2G might be used to extend ram semen for fresh AI, or to preserve it for 24 or 48 h with acceptable results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979590"}
{"pmid": "20979591", "title": "Influence of tegaserod on proximal gastric tone and on the perception of gastric distention in functional dyspepsia.", "content": "Influence of tegaserod on proximal gastric tone and on the perception of gastric distention in functional dyspepsia. Abnormalities in gastric sensorimotor function (hypersensitivity to distention and impaired meal accommodation) have been implicated in the pathophysiology of functional dyspepsia (FD). To study the effect of the 5-HT(4) agonist tegaserod on sensitivity to gastric distention and gastric accommodation in FD. Thirty FD patients (7 males, mean age 42 ± 2 years) underwent a gastric barostat study on two separate occasions, 2 weeks apart, after 5 days of pretreatment with placebo or tegaserod 6 mg b.i.d. in a double-blind randomized order. After introduction of the barostat bag, graded isobaric distentions (2 mmHg increments/2 min) were performed to determine gastric compliance and sensitivity to distention. Subsequently, the pressure level was set at intra-abdominal pressure [minimal distending pressure (MDP)] + 2 mmHg for 90 min, with administration of a liquid meal (200 mL; 300 kcal) after 30 min. Tegaserod had no influence on MDP (7.9 ± 0.4 vs 7.4 ± 0.4 mmHg) or fasting gastric compliance (44 ± 10 vs 61 ± 6 mL mmHg(-1)) and on fasting thresholds for first perception (3.6 ± 0.4 vs 4.2 ± 0.2 mmHg above MDP) or discomfort (9.9 ± 0.7 vs 10.5 ± 0.5 mmHg above MDP). Tegaserod did not alter intra-balloon volumes before and after the meal [respectively 146 ± 14 vs 120 ± 11 and 297 ± 28 vs 283 ± 29 mL, not significant (NS)], or the amplitude of the meal-induced gastric relaxation (151 ± 23 vs 162 ± 23 mL, NS). In the subgroup with normal gastric emptying (n = 22), tegaserod significantly enhanced meal-induced accommodation (126 ± 23 vs 175 ± 29 mL, ANOVA P < 0.001). Tegaserod does not alter gastric sensorimotor function in FD patients as a group. In the subgroup with normal gastric emptying, tegaserod 6 mg b.i.d enhanced gastric accommodation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979591"}
{"pmid": "20979594", "title": "Cardiovascular effects elicited by milonine, a new 8,14-dihydromorphinandienone alkaloid.", "content": "Cardiovascular effects elicited by milonine, a new 8,14-dihydromorphinandienone alkaloid. The mechanisms underlying the cardiovascular responses evoked by milonine (i.v.), an alkaloid, were investigated in rats. In normotensive rats, milonine injections produced hypotension and tachycardia, which were attenuated after N(w) -nitro-L-arginine methyl esther (L-NAME; 20 mg/kg, i.v.). In phenylephrine (10 μM), pre-contracted mesenteric artery rings, milonine (10⁻¹⁰ M to 3 × 10⁻⁴ M) caused a concentration-dependent relaxation (EC₅₀ = 1.1 × 10⁻⁶ M, E(max) = 100 ± 0.0%) and this effect was rightward shifted after either removal of the vascular endothelium (EC₅₀ = 1.6 × 10⁻⁵, p < 0.001), or after L-NAME 100 μM (EC₅₀ = 6.2 × 10⁻⁵, p < 0.001), hydroxocobalamin 30 μM (EC₅₀ = 1.1 × 10⁻⁴, p < 0.001) or ODQ 10 μM (EC₅₀ = 1.9 × 10⁻⁴ p < 0.001). In addition, in rabbit aortic endothelial cells, milonine increased NO₃⁻ levels. The relaxant effect induced by milonine was attenuated in the presence of KCl (20 mM), a modulator efflux K(+) (EC₅₀ = 1.2 × 10⁻⁵, p < 0.001), or different potassium channel blockers such as glibenclamide (10 μM) (EC₅₀ = 6.3 × 10⁻⁵, p < 0.001), TEA (1 mM) (EC₅₀ = 2.3 × 10⁻⁵ M, n = 6) or Charybdotoxin (0.2 μM) plus apamin (0.2 μM) (EC₅₀ = 3.9 × 10⁻⁴ M, n = 7). In addition, pre-contraction with high extracellular potassium concentration prevented milonine-induced vasorelaxation (EC₅₀ = 1.0 × 10⁻⁴, p < 0.001). Milonine also reduced CaCl₂ -induced contraction in Ca²(+) -free solution containing KCl (60 mM). In conclusion, using combined functional and biochemical approaches, we demonstrated that the hypotensive and vasorelaxant effects produced by milonine are, at least in part, mediated by the endothelium, likely via nitric oxide release, activation of nitric oxide-cGMP pathway and opening of K(+) channels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979594"}
{"pmid": "20979595", "title": "Comparison between siliconized evacuated glass and plastic blood collection tubes for prothrombin time and activated partial thromboplastin time assay in normal patients, patients on oral anticoagulant therapy and patients with unfractioned heparin therapy.", "content": "Comparison between siliconized evacuated glass and plastic blood collection tubes for prothrombin time and activated partial thromboplastin time assay in normal patients, patients on oral anticoagulant therapy and patients with unfractioned heparin therapy. The study was designed to evaluate whether there was a statistically significant effect between evacuated glass tubes and plastic tubes on prothrombin time (PT) and activated partial thromboplastin time (aPTT). Blood samples were drawn into four different tubes from three patient populations-apparently healthy patients, patients on oral anticoagulant therapy with vitamin K antagonists (OAT-vka) and patients being treated with unfractioned heparin (UFH). Testing was performed on an automated coagulation analyzer, and statistical analysis was achieved using a test of variance (anova). For normal patients, there were no statistically significant differences for the aPTT test; however, there were statistically significant differences for the PT test. For patients on OAT-vka, statistically significant differences were clearly observed between the four tube types for the PT test. For patients treated with UFH, there were no statistically significant differences for the aPTT test. The data showed a statistically significant difference between glass and plastic tubes in the normal population only for the PT test, with consequent repercussions for patients on OAT. This means that appropriate care and validation should take place whenever there is a change in tube type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979595"}
{"pmid": "20979592", "title": "Redox control of β2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1.", "content": "Redox control of β2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1.  β(2) -Glycoprotein I (β(2) GPI) is an abundant plasma protein that is closely linked to blood clotting, as it interacts with various protein and cellular components of the coagulation system. However, the role of β(2) GPI in thrombus formation is unknown. We have recently shown that β(2) GPI is susceptible to reduction by the thiol oxidoreductases thioredoxin-1 and protein disulfide isomerase, and that reduction of β(2) GPI can take place on the platelet surface.  β(2) GPI, reduced by thioredoxin-1, was labeled with the selective sulfhydryl probe N(a)-(3-maleimidylpropionyl)biocytin and subjected to mass spectrometry to identify the specific cysteines involved in the thiol exchange reaction. Binding assays were used to examine the affinity of reduced β(2) GPI for von Willebrand factor (VWF) and the effect of reduced β2GPI on glycoprotein (GP)Ibα binding to VWF. Platelet adhesion to ristocetin-activated VWF was studied in the presence of reduced β(2) GPI. We demonstrate that the Cys288-Cys326 disulfide in domain V of β(2) GPI is the predominant disulfide reduced by thioredoxin-1. Reduced β(2) GPI in vitro displays increased binding to VWF that is dependent on disulfide bond formation. β(2) GPI reduced by thioredoxin-1, in comparison with non-reduced β(2) GPI, leads to increased binding of GPIbα to VWF and increased platelet adhesion to activated VWF. Given the importance of thiol oxidoreductases in thrombus formation, we provide preliminary evidence that the thiol-dependent interaction of β(2) GPI with VWF may contribute to the redox regulation of platelet adhesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979592"}
{"pmid": "20979597", "title": "Model of the complex of Parathyroid hormone-2 receptor and Tuberoinfundibular peptide of 39 residues.", "content": "Model of the complex of Parathyroid hormone-2 receptor and Tuberoinfundibular peptide of 39 residues. We aim to propose interactions between the parathyroid hormone-2 receptor (PTH2R) and its ligand the tuberoinfundibular peptide of 39 residues (TIP39) by constructing a homology model of their complex. The two related peptides parathyroid hormone (PTH) and parathyroid hormone related protein (PTHrP) are compared with the complex to examine their interactions. In the model, the hydrophobic N-terminus of TIP39 is buried in a hydrophobic part of the central cavity between helices 3 and 7. Comparison of the peptide sequences indicates that the main discriminator between the agonistic peptides TIP39 and PTH and the inactive PTHrP is a tryptophan-phenylalanine replacement. The model indicates that the smaller phenylalanine in PTHrP does not completely occupy the binding site of the larger tryptophan residue in the other peptides. As only TIP39 causes internalisation of the receptor and the primary difference being an aspartic acid in position 7 of TIP39 that interacts with histidine 396 in the receptor, versus isoleucine/histidine residues in the related hormones, this might be a trigger interaction for the events that cause internalisation. A model is constructed for the complex and a trigger interaction for full agonistic activation between aspartic acid 7 of TIP39 and histidine 396 in the receptor is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979597"}
{"pmid": "20979596", "title": "The deceptive nature of UVA tanning versus the modest protective effects of UVB tanning on human skin.", "content": "The deceptive nature of UVA tanning versus the modest protective effects of UVB tanning on human skin. The relationship between human skin pigmentation and protection from ultraviolet (UV) radiation is an important element underlying differences in skin carcinogenesis rates. The association between UV damage and the risk of skin cancer is clear, yet a strategic balance in exposure to UV needs to be met. Dark skin is protected from UV-induced DNA damage significantly more than light skin owing to the constitutively higher pigmentation, but an as yet unresolved and important question is what photoprotective benefit, if any, is afforded by facultative pigmentation (i.e. a tan induced by UV exposure). To address that and to compare the effects of various wavelengths of UV, we repetitively exposed human skin to suberythemal doses of UVA and/or UVB over 2 weeks after which a challenge dose of UVA and UVB was given. Although visual skin pigmentation (tanning) elicited by different UV exposure protocols was similar, the melanin content and UV-protective effects against DNA damage in UVB-tanned skin (but not in UVA-tanned skin) were significantly higher. UVA-induced tans seem to result from the photooxidation of existing melanin and its precursors with some redistribution of pigment granules, while UVB stimulates melanocytes to up-regulate melanin synthesis and increases pigmentation coverage, effects that are synergistically stimulated in UVA and UVB-exposed skin. Thus, UVA tanning contributes essentially no photoprotection, although all types of UV-induced tanning result in DNA and cellular damage, which can eventually lead to photocarcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979596"}
{"pmid": "20979600", "title": "SECRET domain of variola virus CrmB protein can be a member of poxviral type II chemokine-binding proteins family.", "content": "SECRET domain of variola virus CrmB protein can be a member of poxviral type II chemokine-binding proteins family. Variola virus (VARV) the causative agent of smallpox, eradicated in 1980, have wide spectrum of immunomodulatory proteins to evade host immunity. Recently additional biological activity was discovered for VARV CrmB protein, known to bind and inhibit tumour necrosis factor (TNF) through its N-terminal domain homologous to cellular TNF receptors. Besides binding TNF, this protein was also shown to bind with high affinity several chemokines which recruit B- and T-lymphocytes and dendritic cells to sites of viral entry and replication. Ability to bind chemokines was shown to be associated with unique C-terminal domain of CrmB protein. This domain named SECRET (Smallpox virus-Encoded Chemokine Receptor) is unrelated to the host proteins and lacks significant homology with other known viral chemokine-binding proteins or any other known protein. De novo modelling of VARV-CrmB SECRET domain spatial structure revealed its apparent structural homology with cowpox virus CC-chemokine binding protein (vCCI) and vaccinia virus A41 protein, despite low sequence identity between these three proteins. Potential ligand-binding surface of modelled VARV-CrmB SECRET domain was also predicted to bear prominent electronegative charge which is characteristic to known orthopoxviral chemokine-binding proteins. Our results suggest that SECRET should be included into the family of poxviral type II chemokine-binding proteins and that it might have been evolved from the vCCI-like predecessor protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979600"}
{"pmid": "20979598", "title": "Correlations between periparturient serum concentrations of non-esterified fatty acids, beta-hydroxybutyric acid, bilirubin, and urea and the occurrence of clinical and subclinical postpartum bovine endometritis.", "content": "Correlations between periparturient serum concentrations of non-esterified fatty acids, beta-hydroxybutyric acid, bilirubin, and urea and the occurrence of clinical and subclinical postpartum bovine endometritis. Postpartum endometritis in cattle is a multifactorial disease with high economic impact. Both, clinical endometritis (CE) and subclinical endometritis (SCE) result in decreased reproductive performance. Results from in vitro studies led to the implication that non-esterified fatty acids (NEFA), beta-hydroxybutyric acid (BHBA), bilirubin, and urea could be used as predictors for endometritis in veterinary practice. In this field study, we set out to establish optimal predictor cut points of these metabolic parameters for the detection of CE and SCE. Serum samples were collected one week prior to parturition (wk -1), in the first week postpartum (wk +1) and between 28 and 35 days postpartum (wk +5) from 209 Holstein-Friesian cows. At wk +5, all cows were examined for signs of CE and SCE. Higher concentrations of urea at wk +1 were associated with increased odds of CE (OR = 1.7, P = 0.04) in primiparous (PP) cows. A predictor cut point of 3.9 mmol/L (sensitivity: 61%, specificity: 70%) was determined. In multiparous (MP) cows, the logistic regression model revealed that higher concentrations of NEFA at wk -1 were associated with increased odds of CE and SCE (healthy vs. CE: OR = 9.1, P = 0.05; healthy vs. SCE: OR = 12.1, P = 0.04). A predictor cut point of 0.3 mmol/L (sensitivity: 38%, specificity: 87% and sensitivity: 35%, specificity: 89%, respectively) was determined. Increasing concentrations of urea at wk +5 were associated with decreased odds of CE (healthy vs. CE: OR = 0.6, P = 0.01; SCE vs. CE: OR = 0.5, P = 0.03). A predictor cut point of 3.8 mmol/L (sensitivity: 52%, specificity: 81%) was determined. For BHBA and bilirubin relationships with CE or SCE were not detected. The corresponding combinations of sensitivity and specificity of the determined predictor cut points were not satisfactory for practical use. Thus, the analysed parameters, i.e. NEFA, BHBA, bilirubin, and urea, at the chosen time points, i.e. at wk -1, at wk +1, and at wk +5 relative to calving, are unsatisfactory for disease prediction. Further research is required to clarify the questions raised by the current study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979598"}
{"pmid": "20979599", "title": "Factors associated with hospital service satisfaction in a sample of Arab subjects with schizophrenia.", "content": "Factors associated with hospital service satisfaction in a sample of Arab subjects with schizophrenia. Assessment of patients' satisfaction with health care services could help to identify the strengths and weaknesses of the system and provide guidance for further development. The study's objectives were to: (i) assess the pattern of satisfaction with hospital care for a sample of people with schizophrenia in Kuwait, using the Verona Service Satisfaction Scale (VSSS-EU); ii) compare the pattern of satisfaction with those of similar studies; and iii) assess the association of VSSS seven domains with a number of variables representing met and unmet needs for care, family caregiver burden, severity of psychopathology, level of psychosocial functioning, socio-demographic characteristics, psychological well-being and objective quality of life. Consecutive outpatients in stable condition and their family caregivers were interviewed with the VSSS-EU and measures of needs for care, caregiver burden, quality of life and psychopathology. There were 130 patients (66.1%m, mean age 36.8). While over two-thirds expressed satisfaction with the domains of \"overall satisfaction\", \"professionals' skills\", \"access\", \"efficacy\", and \"relatives' involvement\", only about one-third were satisfied with the domains of \"information\" and \"types of intervention\". The later two domains were the areas in which European patients had better satisfaction than our patients, while our patients expressed better satisfaction than the Europeans in the domain of \"relatives' involvement\". In multiple regression analyses, self-esteem, positive and negative affect were the most important correlates of the domains of service satisfaction, while clinical severity, caregiver burden and health unmet needs for care played relatively minor roles. The noted differences and similarities with the international data, as well as the predictive power of self-esteem and affective state, support the impression that patients' attitudes towards psychiatric care involve a complex relationship between clinical, personal and socio-cultural characteristics; and that many of the factors that impact on satisfaction with service relate to individual psychological characteristics. The weaknesses in the system, highlighted by the pattern of responses of the participants, indicate possible gaps in the provision of comprehensive psychiatric care in the country and obviate the need for public mental health education and development of services to enhance the quality of care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979599"}
{"pmid": "20979601", "title": "Performance of three multi-species rapid diagnostic tests for diagnosis of Plasmodium falciparum and Plasmodium vivax malaria in Oromia Regional State, Ethiopia.", "content": "Performance of three multi-species rapid diagnostic tests for diagnosis of Plasmodium falciparum and Plasmodium vivax malaria in Oromia Regional State, Ethiopia. Malaria transmission in Ethiopia is unstable and variable, caused by both Plasmodium falciparum and Plasmodium vivax. The Federal Ministry of Health (FMoH) is scaling up parasitological diagnosis of malaria at all levels of the health system; at peripheral health facilities this will be through use of rapid diagnostic tests (RDTs). The present study compared three RDT products to provide the FMoH with evidence to guide appropriate product selection. Performance of three multi-species (pf-HRP2/pan-pLDH and pf-HRP2/aldolase) RDTs (CareStart, ParaScreen and ICT Combo) was compared with 'gold standard' microscopy at three health centres in Jimma zone, Oromia Regional State. Ease of RDT use by health extension workers was assessed at community health posts. RDT heat stability was tested in a controlled laboratory setting according to WHO procedures. A total of 2,383 patients with suspected malaria were enrolled between May and July 2009, 23.2% of whom were found to be infected with Plasmodium parasites by microscopy. All three RDTs were equally sensitive in detecting P. falciparum or mixed infection: 85.6% (95% confidence interval 81.2-89.4). RDT specificity was similar for detection of P. falciparum or mixed infection at around 92%. For detecting P. vivax infection, all three RDTs had similar sensitivity in the range of 82.5 to 85.0%. CareStart had higher specificity in detecting P. vivax (97.2%) than both ParaScreen and ICT Combo (p < 0.001 and p = 0.05, respectively). Health extension workers preferred CareStart and ParaScreen to ICT Combo due to the clear labelling of bands on the cassette, while the 'lab in a pack' style of CareStart was the preferred design. ParaScreen and CareStart passed all heat stability testing, while ICT Combo did not perform as well. CareStart appeared to be the most appropriate option for use at health posts in Ethiopia, considering the combination of quantitative performance, ease of use and heat stability. When new products become available, the choice of multi-species RDT for Ethiopia should be regularly re-evaluated, as it would be desirable to identify a test with higher sensitivity than the ones evaluated here.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979601"}
{"pmid": "20979602", "title": "Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis.", "content": "Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. Idiopathic Pulmonary Fibrosis (IPF) is an unresolved clinical issue. Phosphodiesterases (PDEs) are known therapeutic targets for various proliferative lung diseases. Lung PDE6 expression and function has received little or no attention. The present study aimed to characterize (i) PDE6 subunits expression in human lung, (ii) PDE6 subunits expression and alteration in IPF and (iii) functionality of the specific PDE6D subunit in alveolar epithelial cells (AECs). PDE6 subunits expression in transplant donor (n = 6) and IPF (n = 6) lungs was demonstrated by real-time quantitative (q)RT-PCR and immunoblotting analysis. PDE6D mRNA and protein levels and PDE6G/H protein levels were significantly down-regulated in the IPF lungs. Immunohistochemical analysis showed alveolar epithelial localization of the PDE6 subunits. This was confirmed by qRT-PCR from human primary alveolar type (AT)II cells, demonstrating the down-regulation pattern of PDE6D in IPF-derived ATII cells. In vitro, PDE6D protein depletion was provoked by transforming growth factor (TGF)-β1 in A549 AECs. PDE6D siRNA-mediated knockdown and an ectopic expression of PDE6D modified the proliferation rate of A549 AECs. These effects were mediated by increased intracellular cGMP levels and decreased ERK phosphorylation. Collectively, we report previously unrecognized PDE6 expression in human lungs, significant alterations of the PDE6D and PDE6G/H subunits in IPF lungs and characterize the functional role of PDE6D in AEC proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979602"}
{"pmid": "20979603", "title": "Systematic development of a self-regulation weight-management intervention for overweight adults.", "content": "Systematic development of a self-regulation weight-management intervention for overweight adults. This paper describes the systematic development of an intervention for the prevention of obesity among overweight adults. Its development was guided by the six steps of Intervention Mapping (IM), in which the establishment of program needs, objectives and methods is followed by development of the intervention and an implementation and evaluation plan. Weight gain prevention can be achieved by making small changes in dietary intake (DI) or physical activity (PA). The intervention objectives, derived from self-regulation theory, were to establish goal-oriented behaviour. They were translated into a computer-tailored Internet-delivered intervention consisting of four modules. The intervention includes strategies to target the main determinants of self-regulation, such as feedback and action planning.The first module is intended to ensure adults' commitment to preventing weight gain, choosing behaviour change and action initiation. The second and third modules are intended to evaluate behaviour change, and to adapt action and coping plans. The fourth module is intended to maintain self-regulation of body weight without use of the program.The intervention is being evaluated for its efficacy in an RCT, whose protocol is described in this paper. Primary outcomes are weight, waist circumference and skin-fold thickness. Other outcomes are DI, PA, cognitive mediators and self-regulation skills. The IM protocol helped us integrating insights from various theories. The performance objectives and methods were guided by self-regulation theory but empirical evidence with regard to the effectiveness of theoretical methods was limited. Sometimes, feasibility issues made it necessary to deviate from the original, theory-based plans. With this paper, we provide transparency with regard to intervention development and evaluation. NTR1862.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979603"}
{"pmid": "20979604", "title": "Prevalence and associated factors of smoking among secondary school students in Harare Zimbabwe.", "content": "Prevalence and associated factors of smoking among secondary school students in Harare Zimbabwe. There is a growing epidemic of tobacco use among adolescents in the developing world. However, there is no up to date information on smoking among adolescents. Although in the developing world concerted efforts are being made to control tobacco use, Zimbabwe does not have any documented tobacco control programmes. We estimated the prevalence of smoking among school going secondary school students in Harare, Zimbabwe. A 3-stage stratified random sampling was employed to select six participating schools and students. A descriptive analysis was conducted to describe the demographic characteristics of the participants. The prevalence of smoking was estimated and the comparison of prevalence was performed according to its associated factors. Logistic regression analysis was used to identify risk factors for smoking. 650 students with a mean age 16 years and 47% of them female participated. Prevalence of ever-smoked was 28.8% (95% CI 25.3 to 32.3). Prevalence of ever-smoked among males (37.8%) was significantly (p < 0.001) much higher than among females (18.5%). In the multivariate analysis, smoking was found to be statistically associated with having friends that smoke (OR 2.8), getting involved in physical fights (OR 2.3), alcohol use (OR 5.7), marijuana use (OR 8.1) and having had sexual intercourse (OR 4.4). The study provides recent estimates of prevalence of smoking, and indicates that there is still a high prevalence of smoking among urban secondary school students. Exposure to friends who smoke, risky behaviour like substance abuse, premarital sex and physical fights are significantly associated with smoking. Interventions to stop or reduce the habit should be implemented now and future studies should monitor and evaluate the impact of the interventions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979604"}
{"pmid": "20979605", "title": "A qualitative study of the experiences and expectations of women receiving in-patient postnatal care in one English maternity unit.", "content": "A qualitative study of the experiences and expectations of women receiving in-patient postnatal care in one English maternity unit. Studies consistently highlight in-patient postnatal care as the area of maternity care women are least satisfied with. As part of a quality improvement study to promote a continuum of care from the birthing room to discharge home from hospital, we explored women's expectations and experiences of current in-patient care. For this part of the study, qualitative data from semi-structured interviews were transcribed and analysed using content analyses to identify issues and concepts. Women were recruited from two postnatal wards in one large maternity unit in the South of England, with around 6,000 births a year. Twenty women, who had a vaginal or caesarean birth, were interviewed on the postnatal ward. Identified themes included; the impact of the ward environment; the impact of the attitude of staff; quality and level of support for breastfeeding; unmet information needs; and women's low expectations of hospital based postnatal care. Findings informed revision to the content and planning of in-patient postnatal care, results of which will be reported elsewhere. Women's responses highlighted several areas where changes could be implemented. Staff should be aware that how they inter-act with women could make a difference to care as a positive or negative experience. The lack of support and inconsistent advice on breastfeeding highlights that units need to consider how individual staff communicate information to women. Units need to address how and when information on practical aspects of infant care is provided if women and their partners are to feel confident on the woman's transfer home from hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979605"}
{"pmid": "20979606", "title": "Exploration of transitional life events in individuals with Friedreich ataxia: implications for genetic counseling.", "content": "Exploration of transitional life events in individuals with Friedreich ataxia: implications for genetic counseling. Human development is a process of change, adaptation and growth. Throughout this process, transitional events mark important points in time when one's life course is significantly altered. This study captures transitional life events brought about or altered by Friedreich ataxia, a progressive chronic illness leading to disability, and the impact of these events on an affected individual's life course. Forty-two adults with Friedreich ataxia (18-65y) were interviewed regarding their perceptions of transitional life events. Data from the interviews were coded and analyzed thematically using an iterative process. Identified transitions were either a direct outcome of Friedreich ataxia, or a developmental event altered by having the condition. Specifically, an awareness of symptoms, fear of falling and changes in mobility status were the most salient themes from the experience of living with Friedreich ataxia. Developmental events primarily influenced by the condition were one's relationships and life's work. Friedreich ataxia increased the complexity and magnitude of transitional events for study participants. Transitional events commonly represented significant loss and presented challenges to self-esteem and identity. Findings from this study help alert professionals of potentially challenging times in patients' lives, which are influenced by chronic illness or disability. Implications for developmental counseling approaches are suggested for genetic counseling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979606"}
{"pmid": "20979607", "title": "Clinicopathologic characteristics and prognostic factors of ovarian fibrosarcoma: the results of a multi-center retrospective study.", "content": "Clinicopathologic characteristics and prognostic factors of ovarian fibrosarcoma: the results of a multi-center retrospective study. Ovarian fibrosarcomas are very rare tumors, and therefore, few case studies have evaluated the prognostic factors of this disease. To our knowledge, this study represents the largest study to evaluate the clinical and pathologic factors associated with ovarian fibrosarcoma patients. Thirty-one cases of ovarian fibrosarcoma were retrospectively reviewed, which included medical records for eight patients, and 23 published case reports from 1995 through 2009. Patient treatment regimens included total hysterectomy with bilateral adnexectomy and an omentectomy (BAO) (n = 9), oophorectomy (OR) (n = 8), chemotherapy (CT) (n = 1), BAO followed by chemotherapy (BAO+CT) (n = 11), BAO followed by radiotherapy (BAO+RT) (n = 1), and oophorectomy followed by radiotherapy (OR + RT) (n = 1). The patients of this cohort were staged according to the guidelines of the Federation of Gynecology and Obstetrics (FIGO), with 15, 6, 9, and 1 stage I-IV cases identified, respectively. Mitotic count values were also evaluated from 10 high-power fields (HPFs), and 3 cases had an average mitotic count < 4, 18 cases were between 4 and 10, and 10 cases had an average mitotic count value ≥ 10. The Ki-67 (MIB-1) proliferation index values were grouped according to values that as follows: < 10% (n = 5), between 10% and 50% (n = 9), and ≥ 50% (n = 5). Positive expression of vimentin (100%, 22/22) and negative expression of CD117 (0%, 5/5) were also detected. Moreover, expression of smooth muscle actin (2/18), desmin (1/13), epithelial membrane antigen (0/11), S-100 (1/19), CD99 (0/6), CD34 (1/5), α-inhibin (7/15), estrogen receptor (1/6), and progesterone receptor (1/6) were reported for subsets of the cases examined. After a median follow-up period of 14 months (range, 2-120), the 2-year overall survival rates (OS) and disease-free survival (DFS) rates for all patients were 55.9% and 45.4%, respectively. Cox proportional hazard regression analysis of survival showed that FIGO stage (P = 0.007) and treatment (P = 0.008) were predictive of poor prognosis. Furthermore, patients with stage I tumors that received BAO+CT were associated with a better prognosis. Mitotic activity, and cells positive for Ki-67 were identified as important factors in the diagnosis of ovarian fibrosarcoma. Furthermore, FIGO stage and treatment modalities have the potential to be prognostic factors of survival, with BAO followed by adjuvant chemotherapy associated with an improved treatment outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979607"}
{"pmid": "20979608", "title": "Stages of chronicity in fibromyalgia and pain catastrophising: a cross-sectional study.", "content": "Stages of chronicity in fibromyalgia and pain catastrophising: a cross-sectional study. Fibromyalgia (FM) is a prevalent and disabling disorder characterised by widespread pain and other symptoms such as insomnia, fatigue and depression. Catastrophisation is considered to be a key clinical symptom in FM; however, few studies have investigated how contextual factors, such as catastrophisation, might contribute to the duration of the pain. The present research examined the relationship among pain, catastrophic thinking and FM impact, as a function of stage of chronicity. In this cross-sectional study, the sample of 328 patients diagnosed with FM was divided into 3 groups based on level of chronicity: Group A (6 months to 2 years, N = 46); Group B (2-4 years, N = 59); and Group C (more than 4 years, N = 223). The three subscales of the Pain Catastrophising Scale (PCS), rumination, magnification, and helplessness, were used as predictors of dysfunction. The Fibromyalgia Impact Questionnaire and the McGill Pain Questionnaire were also administered. A hierarchical regression analysis was performed on the entire sample and, subsequently, for each group to determine the effect of the continuous process variables (castastrophising and pain) on the stages of chronicity. Total score and PCS subscales were strongly associated with pain and impact in all the stages of chronicity in FM patients (r = 0.27-0.73, p < 0.05). For Group A, a regression analysis revealed that rumination predicted FM impact beyond the variance accounted for by age and pain. Both magnification and helplessness predicted impact in Group B, and helplessness was a significant predictor of impact in Group C. These findings provide preliminary evidence that stage of chronicity is an important moderator of psychological vulnerability for FM impact and should be taken into account by tailoring psychological interventions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979608"}
{"pmid": "20979609", "title": "Pathogenic landscapes: interactions between land, people, disease vectors, and their animal hosts.", "content": "Pathogenic landscapes: interactions between land, people, disease vectors, and their animal hosts. Landscape attributes influence spatial variations in disease risk or incidence. We present a review of the key findings from eight case studies that we conducted in Europe and West Africa on the impact of land changes on emerging or re-emerging vector-borne diseases and/or zoonoses. The case studies concern West Nile virus transmission in Senegal, tick-borne encephalitis incidence in Latvia, sandfly abundance in the French Pyrenees, Rift Valley Fever in the Ferlo (Senegal), West Nile Fever and the risk of malaria re-emergence in the Camargue, and rodent-borne Puumala hantavirus and Lyme borreliosis in Belgium. We identified general principles governing landscape epidemiology in these diverse disease systems and geographic regions. We formulated ten propositions that are related to landscape attributes, spatial patterns and habitat connectivity, pathways of pathogen transmission between vectors and hosts, scale issues, land use and ownership, and human behaviour associated with transmission cycles. A static view of the \"pathogenecity\" of landscapes overlays maps of the spatial distribution of vectors and their habitats, animal hosts carrying specific pathogens and their habitat, and susceptible human hosts and their land use. A more dynamic view emphasizing the spatial and temporal interactions between these agents at multiple scales is more appropriate. We also highlight the complementarity of the modelling approaches used in our case studies. Integrated analyses at the landscape scale allows a better understanding of interactions between changes in ecosystems and climate, land use and human behaviour, and the ecology of vectors and animal hosts of infectious agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979609"}
{"pmid": "20979610", "title": "Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling.", "content": "Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling. Head and neck squamous cell carcinoma (HNSCC) is a highly lethal cancer that contains cellular and functional heterogeneity. Previously, we enriched a subpopulation of highly tumorigenic head and neck cancer initiating cells (HN-CICs) from HNSCC. However, the molecular mechanisms by which to govern the characteristics of HN-CICs remain unclear. GRP78, a stress-inducible endoplasmic reticulum chaperone, has been reported to play a crucial role in the maintenance of embryonic stem cells, but the role of GRP78 in CICs has not been elucidated. Initially, we recognized GRP78 as a putative candidate on mediating the stemness and tumorigenic properties of HN-CICs by differential systemic analyses. Subsequently, cells with GRP78 anchored at the plasma membrane (memGRP78+) exerted cancer stemness properties of self-renewal, differentiation and radioresistance. Of note, xenotransplantation assay indicated merely 100 memGRP78+ HNSCCs resulted in tumor growth. Moreover, knockdown of GRP78 significantly reduced the self-renewal ability, side population cells and expression of stemness genes, but inversely promoted cell differentiation and apoptosis in HN-CICs. Targeting GRP78 also lessened tumorigenicity of HN-CICs both in vitro and in vivo. Clinically, co-expression of GRP78 and Nanog predicted the worse survival prognosis of HNSCC patients by immunohistochemical analyses. Finally, depletion of GRP78 in HN-CICs induced the expression of Bax, Caspase 3, and PTEN. In summary, memGRP78 should be a novel surface marker for isolation of HN-CICs, and targeting GRP78 signaling might be a potential therapeutic strategy for HNSCC through eliminating HN-CICs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979610"}
{"pmid": "20979611", "title": "Literature-based discovery of diabetes- and ROS-related targets.", "content": "Literature-based discovery of diabetes- and ROS-related targets. Reactive oxygen species (ROS) are known mediators of cellular damage in multiple diseases including diabetic complications. Despite its importance, no comprehensive database is currently available for the genes associated with ROS. We present ROS- and diabetes-related targets (genes/proteins) collected from the biomedical literature through a text mining technology. A web-based literature mining tool, SciMiner, was applied to 1,154 biomedical papers indexed with diabetes and ROS by PubMed to identify relevant targets. Over-represented targets in the ROS-diabetes literature were obtained through comparisons against randomly selected literature. The expression levels of nine genes, selected from the top ranked ROS-diabetes set, were measured in the dorsal root ganglia (DRG) of diabetic and non-diabetic DBA/2J mice in order to evaluate the biological relevance of literature-derived targets in the pathogenesis of diabetic neuropathy. SciMiner identified 1,026 ROS- and diabetes-related targets from the 1,154 biomedical papers (http://jdrf.neurology.med.umich.edu/ROSDiabetes/). Fifty-three targets were significantly over-represented in the ROS-diabetes literature compared to randomly selected literature. These over-represented targets included well-known members of the oxidative stress response including catalase, the NADPH oxidase family, and the superoxide dismutase family of proteins. Eight of the nine selected genes exhibited significant differential expression between diabetic and non-diabetic mice. For six genes, the direction of expression change in diabetes paralleled enhanced oxidative stress in the DRG. Literature mining compiled ROS-diabetes related targets from the biomedical literature and led us to evaluate the biological relevance of selected targets in the pathogenesis of diabetic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979611"}
{"pmid": "20979612", "title": "The European primary care monitor: structure, process and outcome indicators.", "content": "The European primary care monitor: structure, process and outcome indicators. Scientific research has provided evidence on benefits of well developed primary care systems. The relevance of some of this research for the European situation is limited.There is currently a lack of up to date comprehensive and comparable information on variation in development of primary care, and a lack of knowledge of structures and strategies conducive to strengthening primary care in Europe. The EC funded project Primary Health Care Activity Monitor for Europe (PHAMEU) aims to fill this gap by developing a Primary Care Monitoring System (PC Monitor) for application in 31 European countries. This article describes the development of the indicators of the PC Monitor, which will make it possible to create an alternative model for holistic analyses of primary care. A systematic review of the primary care literature published between 2003 and July 2008 was carried out. This resulted in an overview of: (1) the dimensions of primary care and their relevance to outcomes at (primary) health system level; (2) essential features per dimension; (3) applied indicators to measure the features of primary care dimensions. The indicators were evaluated by the project team against criteria of relevance, precision, flexibility, and discriminating power. The resulting indicator set was evaluated on its suitability for Europe-wide comparison of primary care systems by a panel of primary care experts from various European countries (representing a variety of primary care systems). The developed PC Monitor approaches primary care in Europe as a multidimensional concept. It describes the key dimensions of primary care systems at three levels: structure, process, and outcome level. On structure level, it includes indicators for governance, economic conditions, and workforce development. On process level, indicators describe access, comprehensiveness, continuity, and coordination of primary care services. On outcome level, indicators reflect the quality, and efficiency of primary care. A standardized instrument for describing and comparing primary care systems has been developed based on scientific evidence and consensus among an international panel of experts, which will be tested to all configurations of primary care in Europe, intended for producing comparable information. Widespread use of the instrument has the potential to improve the understanding of primary care delivery in different national contexts and thus to create opportunities for better decision making.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979612"}
{"pmid": "20979615", "title": "Are chiropractors in the uk primary healthcare or primary contact practitioners?: a mixed methods study.", "content": "Are chiropractors in the uk primary healthcare or primary contact practitioners?: a mixed methods study. One of the debates regarding the role of chiropractors is whether or not they should be considered as primary healthcare practitioners. Primary care is often used to describe chiropractic but without any definition of what is meant by the term. Primary healthcare itself has many definitions and this adds to the problem. Existing research literature, based mostly in the USA, suggests that the use of the title \"primary healthcare professional\" by chiropractors is central to the identity of the profession. It has also been suggested that the concept of primary care is misused by chiropractors because they have not examined the concept in detail and thus do not understand it. For the sake of quality of patient care and for the legitimacy of the profession, chiropractors in the UK need to agree on their healthcare role. This study aimed to examine the opinions of chiropractors towards the use of the term primary healthcare when applied to chiropractic practice within the UK. A sequential study of exploratory design was used; this model is characterised by an initial phase of qualitative data collection and analysis that precedes and informs the quantitative phase of data collection and analysis. In this study, interviews with members of chiropractic teaching faculty were used to inform the development of a questionnaire used to survey the opinions of chiropractors in the UK. There was a general consensus of opinion that chiropractors are primary contact practitioners, who work in a primary healthcare setting and that to be able to fulfil this healthcare role, chiropractors must be able to diagnose patients and refer when required. Participants did not feel that chiropractors are able to treat all of the most common medical conditions that present in a primary healthcare setting. The findings of this study suggest that chiropractors in the UK view their role as one of a primary contact healthcare practitioner and that this view is held irrespective of the country in which they were educated or the length of time in practice.Further research needs to be developed to evaluate the findings of the current study within a wider healthcare context. In particular the opinions of other healthcare professionals towards the role of chiropractors in healthcare, need to be examined in more detail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979615"}
{"pmid": "20979613", "title": "Anti-cancer and potential chemopreventive actions of ginseng by activating Nrf2 (NFE2L2) anti-oxidative stress/anti-inflammatory pathways.", "content": "Anti-cancer and potential chemopreventive actions of ginseng by activating Nrf2 (NFE2L2) anti-oxidative stress/anti-inflammatory pathways.  This article reviews recent basic and clinical studies of ginseng, particularly the anti-cancer effects and the potential chemopreventive actions by activating the transcriptional factor, nuclear factor (erythroid-derived 2)-like 2 (Nrf2 or NFE2L2)-mediated anti-oxidative stress or anti-inflammatory pathways. Nrf2 is a novel target for cancer prevention as it regulates the antioxidant responsive element (ARE), a critical regulatory element in the promoter region of genes encoding cellular phase II detoxifying and anti-oxidative stress enzymes. The studies on the chemopreventive effects of ginseng or its components/products showed that Nrf2 could also be a target for ginseng's actions. A number of papers also demonstrated the anti-inflammatory effects of ginseng. Targeting Nrf2 pathway is a novel approach to the investigation of ginseng's cancer chemopreventive actions, including some oxidative stress and inflammatory conditions responsible for the initiation, promotion and progression of carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979613"}
{"pmid": "20979614", "title": "Regulation of Ack1 localization and activity by the amino-terminal SAM domain.", "content": "Regulation of Ack1 localization and activity by the amino-terminal SAM domain. The mechanisms that regulate the activity of the nonreceptor tyrosine kinase Ack1 (activated Cdc42-associated kinase) are poorly understood. The amino-terminal region of Ack1 is predicted to contain a sterile alpha motif (SAM) domain. SAM domains share a common fold and mediate protein-protein interactions in a wide variety of proteins. Here, we addressed the importance of the Ack1 SAM domain in kinase activity. We used immunofluorescence and Western blotting to show that Ack1 deletion mutants lacking the N-terminus displayed significantly reduced autophosphorylation in cells. A minimal construct comprising the N-terminus and kinase domain (NKD) was autophosphorylated, while the kinase domain alone (KD) was not. When expressed in mammalian cells, NKD localized to the plasma membrane, while KD showed a more diffuse cytosolic localization. Co-immunoprecipitation experiments showed a stronger interaction between full length Ack1 and NKD than between full length Ack1 and KD, indicating that the N-terminus was important for Ack1 dimerization. Increasing the local concentration of purified Ack1 kinase domain at the surface of lipid vesicles stimulated autophosphorylation and catalytic activity, consistent with a requirement for dimerization and trans-phosphorylation for activity. Collectively, the data suggest that the N-terminus of Ack1 promotes membrane localization and dimerization to allow for autophosphorylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979614"}
{"pmid": "20979616", "title": "Occupational illnesses in the 2009 Zambian labour force survey.", "content": "Occupational illnesses in the 2009 Zambian labour force survey. Occupational health has received limited research attention in the Southern African Development Community (SADC). Much of the published data in this region come from South Africa and little has been reported north of the Limpopo. The present study was conducted to estimate the burden of occupational illnesses in Zambia and assess factors associated with their occurrence. Data were obtained from the Zambian Labour Force Survey of 2009. Frequencies were used to estimate the prevalence of occupational diseases. Logistic regression analyses were conducted to determine the associations between demographic, social and economic factors and reported illness resulting from occupational exposures. Odds ratios (OR) from bivariate analyses and adjusted odds ratios (AOR) from the multivariate analysis together with their 95% Confidence Intervals (CI) are reported. Data on 59,118 persons aged 18 years or older were available for analysis, of which 29805 (50.4%) were males. The proportions of the sample that reported to have suffered from an occupational illness were 12.7% among males and 10.4% among females (p < 0.001). Overall the proportions of respondents who reported suffering from fatigue, fever and chest infections were 38.8%, 21.7% and 17.1%, respectively. About two thirds (69.7%) of the study participants had stayed away from work due to the illness suffered at work; there was no sex differences (p = 0.216). Older age, being male, lower education level, married/cohabiting or once married (separated/divorced/widowed), and paid employee or employer/self employed were positively associated with having suffered from illness. The findings from this study call for urgent effort for specific measures to prevent and mitigate the effects of occupational injuries. These interventions may include: public health campaigns, enforcement or change in work policies and regulations. Special attention may have to be made towards those who were more likely to suffer from occupational illnesses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979616"}
{"pmid": "20979617", "title": "Statistical techniques to construct assays for identifying likely responders to a treatment under evaluation from cell line genomic data.", "content": "Statistical techniques to construct assays for identifying likely responders to a treatment under evaluation from cell line genomic data. Developing the right drugs for the right patients has become a mantra of drug development. In practice, it is very difficult to identify subsets of patients who will respond to a drug under evaluation. Most of the time, no single diagnostic will be available, and more complex decision rules will be required to define a sensitive population, using, for instance, mRNA expression, protein expression or DNA copy number. Moreover, diagnostic development will often begin with in-vitro cell-line data and a high-dimensional exploratory platform, only later to be transferred to a diagnostic assay for use with patient samples. In this manuscript, we present a novel approach to developing robust genomic predictors that are not only capable of generalizing from in-vitro to patient, but are also amenable to clinically validated assays such as qRT-PCR. Using our approach, we constructed a predictor of sensitivity to dacetuzumab, an investigational drug for CD40-expressing malignancies such as lymphoma using genomic measurements of cell lines treated with dacetuzumab. Additionally, we evaluated several state-of-the-art prediction methods by independently pairing the feature selection and classification components of the predictor. In this way, we constructed several predictors that we validated on an independent DLBCL patient dataset. Similar analyses were performed on genomic measurements of breast cancer cell lines and patients to construct a predictor of estrogen receptor (ER) status. The best dacetuzumab sensitivity predictors involved ten or fewer genes and accurately classified lymphoma patients by their survival and known prognostic subtypes. The best ER status classifiers involved one or two genes and led to accurate ER status predictions more than 85% of the time. The novel method we proposed performed as well or better than other methods evaluated. We demonstrated the feasibility of combining feature selection techniques with classification methods to develop assays using cell line genomic measurements that performed well in patient data. In both case studies, we constructed parsimonious models that generalized well from cell lines to patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979617"}
{"pmid": "20979619", "title": "Clinical features of the initial cases of 2009 pandemic influenza A (H1N1) virus infection in an university hospital of Morocco.", "content": "Clinical features of the initial cases of 2009 pandemic influenza A (H1N1) virus infection in an university hospital of Morocco. The first case of 2009 pandemic influenza A (H1N1) virus infection in our center was documented on June 15. Subsequently, persons with suspected cases of infection and contacts of those with suspected infection were tested. Persons in whom infection was confirmed were hospitalized and quarantined, and some of them were closely observed for the purpose of investigating the nature and duration of the disease. The aim of the present study was to describe baseline characteristics, treatment, outcomes, hospital length of stay and mortality of the first 186 cases of influenza A (H1N1) virus infection, with special interest in those developing severe respiratory failure with intensive care unit (ICU) care requirement. observational study of 186 consecutive cases of influenza A (H1N1) virus infection admitted in 3 departments that were reference centers for the care of patients with influenza A and 4 ICU in Ibn Sina university hospital (Rabat, Morocco) between June and December 2009. Real time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) testing was used to confirm infection. Demographic data, symptoms, comorbid conditions, illness progression, laboratory and chest radiologic findings, treatments, clinical outcomes and ICU care requirement were closely monitored. The mean age of the 186 patients was 17.6 ± 14.8 years, 47.8% had less than 14 years and 57% were male. The median duration of symptoms before hospital admission was 3 days (interquartile range (IQR): 2-5). The most common symptoms were fever (in 91.5% of the patients), cough in 92.5%, and nasal congestion in 62.4%. Twenty four percent of patients had comorbid respiratory disorders and 7.5% were pregnant. Abnormalities in chest radiography were detected in 26.3% of 186 patients on admission or after hospitalization. Twenty patients have required ICU care and 10 have required mechanical ventilation. The hospital length of stay was 5 days (IQR: 4-5). The following were risk factors of ICU admission: older age (p = 0.03), long duration of symptoms (p = 0.07), asthma (p = 0.01), obesity (P < 0.001), abnormalities of chest radiography (P < 0.001), leukocytosis (p = 0.005), and higher C-reactive protein (CRP) (P < 0.001). The ICU length of stay was 4 days (IQR: 3-6.7). The mortality rate was 3.5% among all patients and 30% among ICU patients. Close observation of patients infected with the 2009 pandemic influenza A (H1N1) virus infection provided us with several information. The influenza A (H1N1) virus infection affected young people particularly, with comorbid respiratory disorders. Risk factors of ICU admission were older age, long duration of symptoms, asthma, obesity, abnormalities of chest radiography, leukocytosis and higher CRP. Clinicians should be aware of complications of influenza A (H1N1) virus infection, particulary in patients with risk factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979619"}
{"pmid": "20979618", "title": "The expression and significance of proto-oncogene c-fos in viral myocarditis.", "content": "The expression and significance of proto-oncogene c-fos in viral myocarditis. c-fos may play a role in the pathogenesis of some diseases. The expression and function of c-fos in viral myocarditis (VMC) have not yet been reported. To study the change and significance of proto-oncogene c-fos in VMC is the objective of this experiment. An animal model of VMC was established via coxsackie virus B3 inoculation. VMC mice were then treated with a c-fos monoclonal antibody and isoproterenol and the protein and mRNA expression of c-fos were studied via immunohistochemical analysis and in situ hybridization. Results were simultaneously analyzed for the significance of c-fos expression in mice with VMC. Myocardial necrosis and cell infiltration decreased after treatment with c-fos monoclonal antibody compared to control mice, while myocardial necrosis and cell infiltration were increased after treatment with isoproterenol. Positive cardiomyocytes with c-Fos expression increased at 3, 5, 7, 9, and 15 days after virus inoculation in VMC mice compared to control mice, while returning to almost normal levels at 35 days. The expression level of c-fos mRNA at 3 and 7 days after virus inoculation in VMC mice was also higher than that of control mice. c-fos expression in the cardiomyocytes of VMC mice is significantly increased, c-fos plays an important role in myocardial lesions. The apparent increase in expression of c-fos is likely to be involved in the pathogenesis of VMC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979618"}
{"pmid": "20979620", "title": "Audience response technology: engaging and empowering non-medical prescribing students in pharmacology learning.", "content": "Audience response technology: engaging and empowering non-medical prescribing students in pharmacology learning. Non-medical prescribing (NMP) is a six month course for nurses and certain allied health professionals. It is critical that these students develop a good understanding of pharmacology; however, many students are mature learners with little or no formal biological science knowledge and struggle with the pharmacology component. The implications for patient safety are profound, therefore we encourage students not just to memorise enough pharmacology to pass the exam but to be able to integrate it into clinical practice. Audience response technology (ART), such as the KeePad system (KS) has been shown to promote an active approach to learning and provide instant formative feedback. The aim of this project, therefore, was to incorporate and evaluate the use the KS in promoting pharmacology understanding in NMP students. Questions were incorporated into eight pharmacology lectures, comprising a mix of basic and clinical pharmacology, using TurningPoint software. Student (n = 33) responses to questions were recorded using the KS software and the percentage of students getting the question incorrect and correct was made immediately available in the lecture in graphical form. Survey data collected from these students investigated student perceptions on the use of the system generally and specifically as a learning tool. More in depth discussion of the usefulness of the KS was derived from a focus group comprising 5 students. 100% of students enjoyed using the KS and felt it promoted their understanding of key concepts; 92% stated that it helped identify their learning needs and 87% agreed that the technology was useful in promoting integration of concepts. The most prevalent theme within feedback was that of identifying their own learning needs. Analysis of data from the focus group generated similar themes, with the addition of improving teaching. Repeated questioning produced a significant increase (p < 0.05) in student knowledge of specific pharmacological concepts. The use of ART enhanced non-medical prescribing students' experience of pharmacology teaching. Student perceptions were that this system increased their ability to identify learning needs and promoted understanding and integration of concepts. Students also reported that the technology aided exam revision and reduced associated anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979620"}
{"pmid": "20979621", "title": "Differential expression analysis for sequence count data.", "content": "Differential expression analysis for sequence count data. High-throughput sequencing assays such as RNA-Seq, ChIP-Seq or barcode counting provide quantitative readouts in the form of count data. To infer differential signal in such data correctly and with good statistical power, estimation of data variability throughout the dynamic range and a suitable error model are required. We propose a method based on the negative binomial distribution, with variance and mean linked by local regression and present an implementation, DESeq, as an R/Bioconductor package.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979621"}
{"pmid": "20979622", "title": "What should be done with antisocial personality disorder in the new edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V)?", "content": "What should be done with antisocial personality disorder in the new edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V)? Antisocial personality disorder, psychopathy, dissocial personality disorder and sociopathy are constructs that have generally been used to predict recidivism and dangerousness, alongside being used to exclude patients from treatment services. However, 'antisocial personality disorder' has recently begun to emerge as a treatment diagnosis, a development reflected within cognitive behaviour therapy and mentalisation-based psychotherapy. Many of the behaviour characteristics of antisocial personality disorder are, at the same time, being targeted by interventions at criminal justice settings. A significantly higher proportion of published articles focusing on antisocial personality concern treatment when compared to articles on psychopathy. Currently, the proposal for antisocial personality disorder for the Diagnostic and Statistical Manual of Mental Disorders, fifth edition, suggests a major change in the criteria for this disorder. While the present definition focuses mainly on observable behaviours, the proposed revision stresses interpersonal and emotional aspects of the disorder drawing on the concept of psychopathy. The present commentary suggests that developments leading to improvement in the diagnosis of this type of disorder should, rather than focusing exclusively on elements such as dangerousness and risk assessment, point us to ways in which patients can be treated for their problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979622"}
{"pmid": "20979624", "title": "Patients' experiences and perceived causes of persisting discomfort following day surgery.", "content": "Patients' experiences and perceived causes of persisting discomfort following day surgery. The aim of this study was to describe patients' experiences and perceived causes of persisting discomfort following day surgery. Earlier research has mainly covered symptoms and signs during a recovery period of up to one month, and not dealt with patients' perceptions of what causes persisting, longer-term discomfort. This study is a part from a study carried out during the period May 2006 to May 2007 with a total of 298 day surgery patients. Answers were completed by 118 patients at 48 hours, 110 at seven days and 46 at three months to one open-ended question related to discomfort after day surgery constructed as follows: If you are still experiencing discomfort related to the surgery, what is the reason, in your opinion? Data was processed, quantitatively and qualitatively. Descriptive, inferential, correlation and content analyses were performed. The results suggest that patients suffer from remaining discomfort e.g. pain and wound problem, with effects on daily life following day surgery up to three months. Among patients' perceptions of factors leading to discomfort may be wrongful or suboptimal treatment, type of surgery or insufficient access to provider/information. The results have important implications for preventing and managing discomfort at home following day surgery, and for nursing interventions to help patients handle the recovery period better.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979624"}
{"pmid": "20979623", "title": "The effects of a commercially available botanical supplement on strength, body composition, power output, and hormonal profiles in resistance-trained males.", "content": "The effects of a commercially available botanical supplement on strength, body composition, power output, and hormonal profiles in resistance-trained males. Fenugreek (Trigonella foenum-graecum) is a leguminous, annual plant originating in India and North Africa. In recent years Fenugreek has been touted as an ergogenic aid. The purpose of this study was to evaluate the effects of Fenugreek supplementation on strength and body composition. 49 Resistance trained men were matched according to body weight and randomly assigned to ingest in a double blind manner capsules containing 500 mg of a placebo (N = 23, 20 ± 1.9 years, 178 ± 6.3 cm, 85 ± 12.7 kg, 17 ± 5.6 %BF) or Fenugreek (N = 26, 21 ± 2.8 years, 178 ± 6 cm, 90 ± 18.2 kg, 19.3 ± 8.4 %BF). Subjects participated in a supervised 4-day per week periodized resistance-training program split into two upper and two lower extremity workouts per week for a total of 8-weeks. At 0, 4, and 8-weeks, subjects underwent hydrodensiometery body composition, 1-RM strength, muscle endurance, and anaerobic capacity testing. Data were analyzed using repeated measures ANOVA and are presented as mean ± SD changes from baseline after 60-days. No significant differences (p > 0.05) between groups were noted for training volume. Significant group × time interaction effects were observed among groups in changes in body fat (FEN: -2.3 ± 1.4%BF; PL: -0.39 ± 1.6 %BF, p < 0.001), leg press 1-RM (FEN: 84.6 ± 36.2 kg; PL: 48 ± 29.5 kg, p < 0.001), and bench press 1-RM (FEN: 9.1 ± 6.9 kg; PL: 4.3 ± 5.6 kg, p = 0.01). No significant interactions was observed among groups for Wingate power analysis (p = 0.95) or muscular endurance on bench press (p = 0.87) or leg press (p = 0.61). In addition, there were no changes among groups in any clinical safety data including lipid panel, liver function, kidney function, and/or CBC panel (p > 0.05). It is concluded that 500 mg of this proprietary Fenugreek extraction had a significant impact on both upper- and lower-body strength and body composition in comparison to placebo in a double blind controlled trial. These changes were obtained with no clinical side effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979623"}
{"pmid": "20979625", "title": "Molecular characterization of porcine circovirus 2 isolated from diseased pigs co-infected with porcine reproductive and respiratory syndrome virus.", "content": "Molecular characterization of porcine circovirus 2 isolated from diseased pigs co-infected with porcine reproductive and respiratory syndrome virus. In this study, we isolated a porcine circovirus 2 (PCV2) strain from piglets co-infected with porcine reproductive and respiratory syndrome virus (PRRSV). The complete genome of this strain was sequenced, phylogenetic and polymorphic analyses were carried out. BLAST searches revealed the highest sequence identity (99.5% nt and 99.3% aa) to Guangxi strain EF675230. The phylogenetic tree showed that clustering of the isolates didn't strongly correlate to geographical distribution. Polymorphic analyses demonstrated that the amino acids at most of the polymorphic sites in Open Reading Frame 1(ORF1) and 2 (ORF2)belong to the same amino acid group according to chemical or structural properties, and revealed that highly polymorphic regions overlapped with the known immunoreactive epitopes of ORF2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979625"}
{"pmid": "20979626", "title": "Evaluation of the public health impacts of traffic congestion: a health risk assessment.", "content": "Evaluation of the public health impacts of traffic congestion: a health risk assessment. Traffic congestion is a significant issue in urban areas in the United States and around the world. Previous analyses have estimated the economic costs of congestion, related to fuel and time wasted, but few have quantified the public health impacts or determined how these impacts compare in magnitude to the economic costs. Moreover, the relative magnitudes of economic and public health impacts of congestion would be expected to vary significantly across urban areas, as a function of road infrastructure, population density, and atmospheric conditions influencing pollutant formation, but this variability has not been explored. In this study, we evaluate the public health impacts of ambient exposures to fine particulate matter (PM2.5) concentrations associated with a business-as-usual scenario of predicted traffic congestion. We evaluate 83 individual urban areas using traffic demand models to estimate the degree of congestion in each area from 2000 to 2030. We link traffic volume and speed data with the MOBILE6 model to characterize emissions of PM2.5 and particle precursors attributable to congestion, and we use a source-receptor matrix to evaluate the impact of these emissions on ambient PM2.5 concentrations. Marginal concentration changes are related to a concentration-response function for mortality, with a value of statistical life approach used to monetize the impacts. We estimate that the monetized value of PM2.5-related mortality attributable to congestion in these 83 cities in 2000 was approximately $31 billion (2007 dollars), as compared with a value of time and fuel wasted of $60 billion. In future years, the economic impacts grow (to over $100 billion in 2030) while the public health impacts decrease to $13 billion in 2020 before increasing to $17 billion in 2030, given increasing population and congestion but lower emissions per vehicle. Across cities and years, the public health impacts range from more than an order of magnitude less to in excess of the economic impacts. Our analyses indicate that the public health impacts of congestion may be significant enough in magnitude, at least in some urban areas, to be considered in future evaluations of the benefits of policies to mitigate congestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979626"}
{"pmid": "20979628", "title": "Co-infection of Influenza B and Streptococci causing severe pneumonia and septic shock in healthy women.", "content": "Co-infection of Influenza B and Streptococci causing severe pneumonia and septic shock in healthy women. Since the Influenza A pandemic in 1819, the association between the influenza virus and Streptococcus pneumoniae has been well described in literature. While a leading role has been so far attributed solely to Influenza A as the primary infective pathogen, Influenza B is generally considered to be less pathogenic with little impact on morbidity and mortality of otherwise healthy adults. This report documents the severe synergistic pathogenesis of Influenza B infection and bacterial pneumonia in previously healthy persons not belonging to a special risk population and outlines therapeutic options in this clinical setting. During the seasonal influenza epidemic 2007/2008, three previously healthy women presented to our hospital with influenza-like symptoms and rapid clinical deterioration. Subsequent septic shock due to severe bilateral pneumonia necessitated intensive resuscitative measures including the use of an interventional lung assist device. Microbiological analysis identified severe dual infections of Influenza B with Streptococcus pyogenes in two cases and Streptococcus pneumoniae in one case. The patients presented with no evidence of underlying disease or other known risk factors for dual infection such as age (< one year, > 65 years), pregnancy or comorbidity. Influenza B infection can pose a risk for severe secondary infection in previously healthy persons. As patients admitted to hospital due to severe pneumonia are rarely tested for Influenza B, the incidence of admission due to this virus might be greatly underestimated, therefore, a more aggressive search for influenza virus and empirical treatment might be warranted. While the use of an interventional lung assist device offers a potential treatment strategy for refractory respiratory acidosis in addition to protective lung ventilation, the combined empiric use of a neuraminidase-inhibitor and antibiotics in septic patients with pulmonary manifestations during an epidemic season should be considered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979628"}
{"pmid": "20979627", "title": "ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells.", "content": "ARTEMIS stabilizes the genome and modulates proliferative responses in multipotent mesenchymal cells. Unrepaired DNA double-stranded breaks (DSBs) cause chromosomal rearrangements, loss of genetic information, neoplastic transformation or cell death. The nonhomologous end joining (NHEJ) pathway, catalyzing sequence-independent direct rejoining of DSBs, is a crucial mechanism for repairing both stochastically occurring and developmentally programmed DSBs. In lymphocytes, NHEJ is critical for both development and genome stability. NHEJ defects lead to severe combined immunodeficiency (SCID) and lymphoid cancer predisposition in both mice and humans. While NHEJ has been thoroughly investigated in lymphocytes, the importance of NHEJ in other cell types, especially with regard to tumor suppression, is less well documented. We previously reported evidence that the NHEJ pathway functions to suppress a range of nonlymphoid tumor types, including various classes of sarcomas, by unknown mechanisms. Here we investigate roles for the NHEJ factor ARTEMIS in multipotent mesenchymal stem/progenitor cells (MSCs), as putative sarcomagenic cells of origin. We demonstrate a key role for ARTEMIS in sarcoma suppression in a sensitized mouse tumor model. In this context, we found that ARTEMIS deficiency led to chromosomal damage but, paradoxically, enhanced resistance and proliferative potential in primary MSCs subjected to various stresses. Gene expression analysis revealed abnormally regulated stress response, cell proliferation, and signal transduction pathways in ARTEMIS-defective MSCs. Finally, we identified candidate regulatory genes that may, in part, mediate a stress-resistant, hyperproliferative phenotype in preneoplastic ARTEMIS-deficient MSCs. Our discoveries suggest that Art prevents genome damage and restrains proliferation in MSCs exposed to various stress stimuli. We propose that deficiency leads to a preneoplastic state in primary MSCs and is associated with aberrant proliferative control and cellular stress resistance. Thus, our data reveal surprising new roles for ARTEMIS and the NHEJ pathway in normal MSC function and fitness relevant to tumor suppression in mesenchymal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979627"}
{"pmid": "20979630", "title": "The frequency of NPM1 mutations in childhood acute myeloid leukemia.", "content": "The frequency of NPM1 mutations in childhood acute myeloid leukemia. Mutations in the nucleophosmin (NPM1) gene have been solely associated with childhood acute myeloid leukemia (AML). We evaluated the frequency of NPM1 mutations in childhood AML, their relation to clinical and cytogenetic features and the presence of common FLT3 and RAS mutations. NPM1 mutations were found in 8% of cases. They involved the typical type 'A' mutation and one novel mutation characterized by two individual base pair substitutions, which resulted in 2 amino acid changes (W290) and (S293) in the NPM protein. FLT3/ITD mutations were observed in 12% of the cases and in one NPM1-mutated case bearing also t(8;21) (q22;q22). No common RAS mutations were identified. A relatively consistent NPM1 mutation rate was observed, but with variations in types of mutations. The role of different types of NPM1 mutations, either individually or in the presence of other common gene mutations may be essential for childhood AML prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979630"}
{"pmid": "20979629", "title": "Ancient origin of animal U-box ubiquitin ligases.", "content": "Ancient origin of animal U-box ubiquitin ligases. The patterns of emergence and diversification of the families of ubiquitin ligases provide insights about the evolution of the eukaryotic ubiquitination system. U-box ubiquitin ligases (UULs) are proteins characterized by containing a peculiar protein domain known as U box. In this study, the origin of the animal UUL genes is described. Phylogenetic and structural data indicate that six of the seven main UUL-encoding genes found in humans (UBE4A, UBE4B, UIP5, PRP19, CHIP and CYC4) were already present in the ancestor of all current metazoans and the seventh (WDSUB1) is found in placozoans, cnidarians and bilaterians. The fact that only 4-5 genes orthologous to the human ones are present in the choanoflagellate Monosiga brevicollis suggests that several animal-specific cooptions of the U box to generate new genes occurred. Significantly, Monosiga contains five additional UUL genes that are not present in animals. One of them is also present in distantly-related protozoans. Along animal evolution, losses of UUL-encoding genes are rare, except in nematodes, which lack three of them. These general patterns are highly congruent with those found for other two families (RBR, HECT) of ubiquitin ligases. Finding that the patterns of emergence, diversification and loss of three unrelated families of ubiquitin ligases (RBR, HECT and U-box) are parallel indicates that there are underlying, linage-specific evolutionary forces shaping the complexity of the animal ubiquitin system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979629"}
{"pmid": "20979631", "title": "Feedback inhibition of L1 and alu retrotransposition through altered double strand break repair kinetics.", "content": "Feedback inhibition of L1 and alu retrotransposition through altered double strand break repair kinetics. Cells adapt to various chronic toxic exposures in a multitude of ways to minimize further damage and maximize their growth potential. Expression of L1 elements in the human genome can be greatly deleterious to cells, generating numerous double strand breaks (DSBs). Cells have been reported to respond to chronic DSBs by altering the repair of these breaks, including increasing the rate of homology independent DSB repair. Retrotransposition is strongly affected by proteins involved in DSB repair. Therefore, L1 expression has the potential to be a source of chronic DSBs and thus bring about the changes in cellular environment that could ultimately restrict its own retrotransposition. We demonstrate that constitutive L1 expression leads to quicker DSB repair and decreases in the retrotransposition potential of L1 and other retrotransposons dependent on L1 expression for their mobility. This cellular adaptation results in reduced sensitivity to L1 induced toxicity. These effects can be induced by constitutive expression of the functional L1 ORF2 alone, but not by the constitutive expression of an L1 open reading frame 2 with mutations to its endonuclease and reverse transcriptase domains. This adaptation correlates with the relative activity of the L1 introduced into the cells. The increased number of DSBs resulting from constitutive expression of L1 results in a more rapid rate of repair. The cellular response to this L1 expression also results in attenuation of retrotransposition and reduced sensitivity of the cells to negative consequences of L1 ORF2 expression. The influence does not appear to be through RNA interference. We believe that the increased rate of DSB repair is the most likely cause of the attenuation of retrotransposition. These alterations act as a fail safe mechanism that allows cells to escape the toxicity associated with the unchecked L1 expression. This gives cells that overexpress L1, such as tumor cells, the ability to survive the high levels of expression. However, the increased rate of break repair may come at the cost of accuracy of repair of the lesion, resulting in increased genomic instability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979631"}
{"pmid": "20979632", "title": "Assessment of Chronic Illness Care with the German version of the ACIC in different primary care settings in Switzerland.", "content": "Assessment of Chronic Illness Care with the German version of the ACIC in different primary care settings in Switzerland. In Switzerland the extent to which patients with chronic illnesses receive care congruent with the Chronic Care Model (CCM) is unknown. According to guidelines we translated the Assessment of Chronic Illness Care (ACIC) into German (G-ACIC). We tested the instrument in different primary care settings and compared subscales with the original testing. Difficulties encountered during the translation process consisted in the difference of health care settings in Switzerland and USA. However initial testing showed the G-ACIC to be a suitable instrument. The average ACIC subscale scores in Swiss managed care (MC)-, group (GP)- and single handed practices (SP) were higher for MC practices than for group- and single handed practices: Organization of the healthcare delivery system: MC mean (m) = 6.80 (SD 1.55), GP m = 5.42 (SD 0.99), SP m = 4.60 (SD 2.07); community linkages: MC m = 4.19 (SD 1.47), GP m = 4.83 (SD 1.81), SP m = 3.10 (SD 2.12); self-management support: MC m = 4.96 (SD 1.13), GP m = 4.73 (SD 1.40), SP m = 4.43 (SD 1.34); decision support: MC m = 4.75 (SD 1.06); GP m = 4.20 (SD 0.87), SP m = 3.25 (SD 1.59); delivery system design: MC m = 5.98 (SD 1.61), GP m = 5.05 (SD 2.05), SP m = 3.86 (SD 1.51) and clinical information systems: MC m = 4.34 (SD = 2.49), GP m = 2.06 (SD 1.35), SP m = 3.20 (SD 1.57). The G-ACIC is applicable and useful for comparing different health care settings in German speaking countries. Managed care organizations seem to implement the different components of the CCM in a greater extend than group and single handed practices. However, much room exists for further improvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979632"}
{"pmid": "20979633", "title": "SMS for Life: a pilot project to improve anti-malarial drug supply management in rural Tanzania using standard technology.", "content": "SMS for Life: a pilot project to improve anti-malarial drug supply management in rural Tanzania using standard technology. Maintaining adequate supplies of anti-malarial medicines at the health facility level in rural sub-Saharan Africa is a major barrier to effective management of the disease. Lack of visibility of anti-malarial stock levels at the health facility level is an important contributor to this problem. A 21-week pilot study, 'SMS for Life', was undertaken during 2009-2010 in three districts of rural Tanzania, involving 129 health facilities. Undertaken through a collaborative partnership of public and private institutions, SMS for Life used mobile telephones, SMS messages and electronic mapping technology to facilitate provision of comprehensive and accurate stock counts from all health facilities to each district management team on a weekly basis. The system covered stocks of the four different dosage packs of artemether-lumefantrine (AL) and quinine injectable. Stock count data was provided in 95% of cases, on average. A high response rate (≥ 93%) was maintained throughout the pilot. The error rate for composition of SMS responses averaged 7.5% throughout the study; almost all errors were corrected and messages re-sent. Data accuracy, based on surveillance visits to health facilities, was 94%. District stock reports were accessed on average once a day. The proportion of health facilities with no stock of one or more anti-malarial medicine (i.e. any of the four dosages of AL or quinine injectable) fell from 78% at week 1 to 26% at week 21. In Lindi Rural district, stock-outs were eliminated by week 8 with virtually no stock-outs thereafter. During the study, AL stocks increased by 64% and quinine stock increased 36% across the three districts. The SMS for Life pilot provided visibility of anti-malarial stock levels to support more efficient stock management using simple and widely available SMS technology, via a public-private partnership model that worked highly effectively. The SMS for Life system has the potential to alleviate restricted availability of anti-malarial drugs or other medicines in rural or under-resourced areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979633"}
{"pmid": "20979635", "title": "MHC allele frequency distributions under parasite-driven selection: A simulation model.", "content": "MHC allele frequency distributions under parasite-driven selection: A simulation model. The extreme polymorphism that is observed in major histocompatibility complex (MHC) genes, which code for proteins involved in recognition of non-self oligopeptides, is thought to result from a pressure exerted by parasites because parasite antigens are more likely to be recognized by MHC heterozygotes (heterozygote advantage) and/or by rare MHC alleles (negative frequency-dependent selection). The Ewens-Watterson test (EW) is often used to detect selection acting on MHC genes over the recent history of a population. EW is based on the expectation that allele frequencies under balancing selection should be more even than under neutrality. We used computer simulations to investigate whether this expectation holds for selection exerted by parasites on host MHC genes under conditions of heterozygote advantage and negative frequency-dependent selection acting either simultaneously or separately. In agreement with simple models of symmetrical overdominance, we found that heterozygote advantage acting alone in populations does, indeed, result in more even allele frequency distributions than expected under neutrality, and this is easily detectable by EW. However, under negative frequency-dependent selection, or under the joint action of negative frequency-dependent selection and heterozygote advantage, distributions of allele frequencies were less predictable: the majority of distributions were indistinguishable from neutral expectations, while the remaining runs resulted in either more even or more skewed distributions than under neutrality. Our results indicate that, as long as negative frequency-dependent selection is an important force maintaining MHC variation, the EW test has limited utility in detecting selection acting on these genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979635"}
{"pmid": "20979634", "title": "Impact of national malaria control scale-up programmes in Africa: magnitude and attribution of effects.", "content": "Impact of national malaria control scale-up programmes in Africa: magnitude and attribution of effects. Since 2005, malaria control scale-up has progressed in many African countries. Controlled studies of insecticide-treated mosquito nets (ITNs), indoor residual spraying (IRS), intermittent preventive treatment during pregnancy (IPTp) and malaria case management suggested that when incorporated into national programmes a dramatic health impact, likely more than a 20% decrease in all-cause childhood mortality, was possible. To assess the extent to which national malaria programmes are achieving impact the authors reviewed African country programme data available through 2009. National survey data, published literature, and organization or country reports produced during 2000-2009 were reviewed to assess available malaria financing, intervention delivery, household or target population coverage, and reported health benefits including infection, illness, severe anaemia, and death. By the end of 2009, reports were available for ITN household ownership (n = 34) and IPTp use (n = 27) in malaria-endemic countries in Africa, with at least two estimates (pre-2005 and post-2005 intervals). Information linking IRS and case management coverage to impact were more limited. There was generally at least a three-fold increase in household ITN ownership across these countries between pre-2005 (median of 2.4% of households with at least one ITN) and post-2005 (median of 32.5% of households with at least one ITN). Ten countries had temporal data to assess programme impact, and all reported progress on at least one impact indicator (typically on mortality); in under-five year mortality rates most observed a decline of more than 20%. The causal relationship between malaria programme scale-up and reduced child illness and mortality rates is supported by biologic plausibility including mortality declines consistent with experience from intervention efficacy trials, consistency of findings across multiple countries and different epidemiologic settings, and temporal congruity where morbidity and mortality declines have been documented in the 18 to 36 months following intervention scale-up. Several factors potentially have contributed to recent health improvement in African countries, but there is substantial evidence that achieving high malaria control intervention coverage, especially with ITNs and targeted IRS, has been the leading contributor to reduced child mortality. The documented impact provides the evidence required to support a global commitment to the expansion and long-term investment in malaria control to sustain and increase the health impact that malaria control is producing in Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979634"}
{"pmid": "20979637", "title": "Automated saccharification assay for determination of digestibility in plant materials.", "content": "Automated saccharification assay for determination of digestibility in plant materials. Cell wall resistance represents the main barrier for the production of second generation biofuels. The deconstruction of lignocellulose can provide sugars for the production of fuels or other industrial products through fermentation. Understanding the biochemical basis of the recalcitrance of cell walls to digestion will allow development of more effective and cost efficient ways to produce sugars from biomass. One approach is to identify plant genes that play a role in biomass recalcitrance, using association genetics. Such an approach requires a robust and reliable high throughput (HT) assay for biomass digestibility, which can be used to screen the large numbers of samples involved in such studies. We developed a HT saccharification assay based on a robotic platform that can carry out in a 96-well plate format the enzymatic digestion and quantification of the released sugars. The handling of the biomass powder for weighing and formatting into 96 wells is performed by a robotic station, where the plant material is ground, delivered to the desired well in the plates and weighed with a precision of 0.1 mg. Once the plates are loaded, an automated liquid handling platform delivers an optional mild pretreatment (< 100°C) followed by enzymatic hydrolysis of the biomass. Aliquots from the hydrolysis are then analyzed for the release of reducing sugar equivalents. The same platform can be used for the comparative evaluation of different enzymes and enzyme cocktails. The sensitivity and reliability of the platform was evaluated by measuring the saccharification of stems from lignin modified tobacco plants, and the results of automated and manual analyses compared. The automated assay systems are sensitive, robust and reliable. The system can reliably detect differences in the saccharification of plant tissues, and is able to process large number of samples with a minimum amount of human intervention. The automated system uncovered significant increases in the digestibility of certain lignin modified lines in a manner compatible with known effects of lignin modification on cell wall properties. We conclude that this automated assay platform is of sufficient sensitivity and reliability to undertake the screening of the large populations of plants necessary for mutant identification and genetic association studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979637"}
{"pmid": "20979636", "title": "HPV vaccine: an overview of immune response, clinical protection, and new approaches for the future.", "content": "HPV vaccine: an overview of immune response, clinical protection, and new approaches for the future. Although long-term protection is a key-point in evaluating HPV-vaccine over time, there is currently inadequate information on the duration of HPV vaccine-induced immunity and on the mechanisms related to the activation of immune-memory. Longer-term surveillance in a vaccinated population is needed to identify waning immunity, evaluating any requirements for booster immunizations to assess vaccine efficacy against HPV-diseases. Current prophylactic vaccines have the primary end-points to protect against HPV-16 and 18, the genotypes more associated to cervical cancer worldwide. Nevertheless, data from many countries demonstrate the presence, at significant levels, of HPVs that are not included in the currently available vaccine preparations, indicating that these vaccines could be less effective in a particular area of the world. The development of vaccines covering a larger number of HPVs presents the most complex challenge for the future. Therefore, long term immunization and cross-protection of HPV vaccines will be discussed in light of new approaches for the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979636"}
{"pmid": "20979638", "title": "Oromotor variability in children with mild spastic cerebral palsy: a kinematic study of speech motor control.", "content": "Oromotor variability in children with mild spastic cerebral palsy: a kinematic study of speech motor control. Treating motor speech dysfunction in children with CP requires an understanding of the mechanism underlying speech motor control. However, there is a lack of literature in quantitative measures of motor control, which may potentially characterize the nature of the speech impairments in these children. This study investigated speech motor control in children with cerebral palsy (CP) using kinematic analysis. We collected 10 children with mild spastic CP, aged 4.8 to 7.5 years, and 10 age-matched children with typical development (TD) from rehabilitation department at a tertiary hospital. All children underwent analysis of percentage of consonants correct (PCC) and kinematic analysis of speech tasks: poly-syllable (PS) and mono-syllable (MS) tasks using the Vicon Motion 370 system integrated with a digital camcorder. Kinematic parameters included spatiotemporal indexes (STIs), and average values and coefficients of variation (CVs) of utterance duration, peak oral opening displacement and velocity. An ANOVA was conducted to determine whether PCC and kinematic data significantly differed between groups. CP group had relatively lower PCCs (80.0-99.0%) than TD group (p = 0.039). CP group had higher STIs in PS speech tasks, but not in MS tasks, than TD group did (p = 0.001). The CVs of utterance duration for MS and PS tasks of children with CP were at least three times as large as those of TD children (p < 0.01). However, average values of utterance duration, peak oral opening displacement and velocity and CVs of other kinematic data for both tasks did not significantly differ between two groups. High STI values and high variability on utterance durations in children with CP reflect deficits in relative spatial and/or especially temporal control for speech in the CP participants compared to the TD participants. Children with mild spastic CP may have more difficulty in processing increased articulatory demands and resulted in greater oromotor variability than normal children. The kinematic data such as STIs can be used as indices for detection of speech motor control impairments in children with mild CP and assessment of the effectiveness in the treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979638"}
{"pmid": "20979640", "title": "Internet-based surveillance of Influenza-like-illness in the UK during the 2009 H1N1 influenza pandemic.", "content": "Internet-based surveillance of Influenza-like-illness in the UK during the 2009 H1N1 influenza pandemic. Internet-based surveillance systems to monitor influenza-like illness (ILI) have advantages over traditional (physician-based) reporting systems, as they can potentially monitor a wider range of cases (i.e. including those that do not seek care). However, the requirement for participants to have internet access and to actively participate calls into question the representativeness of the data. Such systems have been in place in a number of European countries over the last few years, and in July 2009 this was extended to the UK. Here we present results of this survey with the aim of assessing the reliability of the data, and to evaluate methods to correct for possible biases. Internet-based monitoring of ILI was launched near the peak of the first wave of the UK H1N1v influenza pandemic. We compared the recorded ILI incidence with physician-recorded incidence and an estimate of the true number of cases over the course of the epidemic. We also compared overall attack rates. The effect of using different ILI definitions and alternative denominator assumptions on incidence estimates was explored. The crude incidence measured by the internet-based system appears to be influenced by individuals who participated only once in the survey and who appeared more likely to be ill. This distorted the overall incidence trend. Concentrating on individuals who reported more than once results in a time series of ILI incidence that matches the trend of case estimates reasonably closely, with a correlation of 0.713 (P-value: 0.0001, 95% CI: 0.435, 0.867). Indeed, the internet-based system appears to give a better estimate of the relative height of the two waves of the UK pandemic than the physician-recorded incidence. The overall attack rate is, however, higher than other estimates, at about 16% when compared with a model-based estimate of 6%. Internet-based monitoring of ILI can capture the trends in case numbers if appropriate weighting is used to correct for differential response. The overall level of incidence is, however, difficult to measure. Internet-based systems may be a useful adjunct to existing ILI surveillance systems as they capture cases that do not necessarily contact health care. However, further research is required before they can be used to accurately assess the absolute level of incidence in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979640"}
{"pmid": "20979641", "title": "Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement.", "content": "Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement. The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has over 15000 members in the databases, the pairwise sequence identity is typically around 25%, there are members from all kingdoms of life, the chain-lengths vary as does the oligomericity, and the members are partaking in a multitude of biological processes. There are profile hidden Markov models (HMMs) available for detecting MDR superfamily members, but none for determining which MDR family each protein belongs to. The current torrential influx of new sequence data enables elucidation of more and more protein families, and at an increasingly fine granularity. However, gathering good quality training data usually requires manual attention by experts and has therefore been the rate limiting step for expanding the number of available models. We have developed an automated algorithm for HMM refinement that produces stable and reliable models for protein families. This algorithm uses relationships found in data to generate confident seed sets. Using this algorithm we have produced HMMs for 86 distinct MDR families and 34 of their subfamilies which can be used in automated annotation of new sequences. We find that MDR forms with 2 Zn2+ ions in general are dehydrogenases, while MDR forms with no Zn2+ in general are reductases. Furthermore, in Bacteria MDRs without Zn2+ are more frequent than those with Zn2+, while the opposite is true for eukaryotic MDRs, indicating that Zn2+ has been recruited into the MDR superfamily after the initial life kingdom separations. We have also developed a web site http://mdr-enzymes.org that provides textual and numeric search against various characterised MDR family properties, as well as sequence scan functions for reliable classification of novel MDR sequences. Our method of refinement can be readily applied to create stable and reliable HMMs for both MDR and other protein families, and to confidently subdivide large and complex protein superfamilies. HMMs created using this algorithm correspond to evolutionary entities, making resolution of overlapping models straightforward. The implementation and support scripts for running the algorithm on computer clusters are available as open source software, and the database files underlying the web site are freely downloadable. The web site also makes our findings directly useful also for non-bioinformaticians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979641"}
{"pmid": "20979639", "title": "Targeting the osteosarcoma cancer stem cell.", "content": "Targeting the osteosarcoma cancer stem cell.  Osteosarcoma is the most common type of solid bone cancer and the second leading cause of cancer-related death in pediatric patients. Many patients are not cured by the current osteosarcoma therapy consisting of combination chemotherapy along with surgery and thus new treatments are urgently needed. In the last decade, cancer stem cells have been identified in many tumors such as leukemia, brain, breast, head and neck, colon, skin, pancreatic, and prostate cancers and these cells are proposed to play major roles in drug resistance, tumor recurrence, and metastasis. Recent studies have shown evidence that osteosarcoma also possesses cancer stem cells. This review summarizes the current knowledge about the osteosarcoma cancer stem cell including the methods used for its isolation, its properties, and its potential as a new target for osteosarcoma treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979639"}
{"pmid": "20979642", "title": "Gum Guar fiber associated with fructose reduces serum triacylglycerol but did not improve the glucose tolerance in rats.", "content": "Gum Guar fiber associated with fructose reduces serum triacylglycerol but did not improve the glucose tolerance in rats. The increased intake of dietary fructose can be associated with alterations on energy homeostasis and lipid/carbohydrate metabolism, such as insulin resistance and dislipidemia. On the other hand, the ingestion of soluble fiber gum guar could improve benefic mechanism on glucose tolerance and lipids profile. The aim of the present study were to investigate the effects of the supplemental feeding partially hydrolyzed gum guar on glucose and lipid homeostasis, in rats fed with fructose solution. The study was performed on thirty day-old male Wistar rats randomly assigned into four groups: control(C) or treated with fructose (F-20%), fiber (FB-5%), or fructose plus fiber (F-20% + FB-5% = FF) solution for 30 days on glucose tolerance (OGTT), triacylglycerol concentration in the liver by chloroform/methanol method, glucose, triacylglycerol and total cholesterol serum concentration by assayed by enzymatic colorimetric method, insulin receptor (IR) concentration in the liver by Western Blotting. The total body weight gain was not different between groups; in regards of total caloric intake, in the F group was significantly higher and in the FB group was lower than other groups. The triacylglycerol concentration in the liver of FF group was significantly higher than F group, the triacylglycerol concentration in the serum was higher the F group compared with other groups. The OGTT reveal impaired on glucose tolerance in the F, FB, FF compared with C. The IR concentration in the liver was lower in the F, FB, FF compared with C, no significant difference was observed between groups for IR concentration in the gastrocnemius muscle. No significant difference was observed between groups for carcass fat content and serum total cholesterol. Fructose induced important alterations on glucose tolerance and lipid metabolism, despite of fiber showed reversion of part this alterations. The association fructose plus fiber to seem decrease insulin receptor concentration in the liver, with consequent impair on glucose tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979642"}
{"pmid": "20979643", "title": "Gene discovery from Jatropha curcas by sequencing of ESTs from normalized and full-length enriched cDNA library from developing seeds.", "content": "Gene discovery from Jatropha curcas by sequencing of ESTs from normalized and full-length enriched cDNA library from developing seeds. Jatropha curcas L. is promoted as an important non-edible biodiesel crop worldwide. Jatropha oil, which is a triacylglycerol, can be directly blended with petro-diesel or transesterified with methanol and used as biodiesel. Genetic improvement in jatropha is needed to increase the seed yield, oil content, drought and pest resistance, and to modify oil composition so that it becomes a technically and economically preferred source for biodiesel production. However, genetic improvement efforts in jatropha could not take advantage of genetic engineering methods due to lack of cloned genes from this species. To overcome this hurdle, the current gene discovery project was initiated with an objective of isolating as many functional genes as possible from J. curcas by large scale sequencing of expressed sequence tags (ESTs). A normalized and full-length enriched cDNA library was constructed from developing seeds of J. curcas. The cDNA library contained about 1 × 10(6) clones and average insert size of the clones was 2.1 kb. Totally 12,084 ESTs were sequenced to average high quality read length of 576 bp. Contig analysis revealed 2258 contigs and 4751 singletons. Contig size ranged from 2-23 and there were 7333 ESTs in the contigs. This resulted in 7009 unigenes which were annotated by BLASTX. It showed 3982 unigenes with significant similarity to known genes and 2836 unigenes with significant similarity to genes of unknown, hypothetical and putative proteins. The remaining 191 unigenes which did not show similarity with any genes in the public database may encode for unique genes. Functional classification revealed unigenes related to broad range of cellular, molecular and biological functions. Among the 7009 unigenes, 6233 unigenes were identified to be potential full-length genes. The high quality normalized cDNA library was constructed from developing seeds of J. curcas for the first time and 7009 unigenes coding for diverse biological functions including oil biosynthesis were identified. These genes will serve as invaluable genetic resource for crop improvement in jatropha to make it an ideal and profitable crop for biodiesel production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979643"}
{"pmid": "20979644", "title": "Dig1 protects against cell death provoked by glyphosate-based herbicides in human liver cell lines.", "content": "Dig1 protects against cell death provoked by glyphosate-based herbicides in human liver cell lines. Worldwide used pesticides containing different adjuvants like Roundup formulations, which are glyphosate-based herbicides, can provoke some in vivo toxicity and in human cells. These pesticides are commonly found in the environment, surface waters and as food residues of Roundup tolerant genetically modified plants. In order to know their effects on cells from liver, a major detoxification organ, we have studied their mechanism of action and possible protection by precise medicinal plant extracts called Dig1. The cytotoxicity pathways of four formulations of glyphosate-based herbicides were studied using human hepatic cell lines HepG2 and Hep3B, known models to study xenobiotic effects. We monitored mitochondrial succinate dehydrogenase activity and caspases 3/7 for cell mortality and protection by Dig1, as well as cytochromes P450 1A1, 1A2, 3A4 and 2C9 and glutathione-S-transferase to approach the mechanism of actions. All the four Roundup formulations provoke liver cell death, with adjuvants having stronger effects than glyphosate alone. Hep3B are 3-5 times more sensitive over 48 h. Caspases 3/7 are greatly activated in HepG2 by Roundup at non-cytotoxic levels, and some apoptosis induction by Roundup is possible together with necrosis. CYP3A4 is specifically enhanced by Roundup at doses 400 times less than used in agriculture (2%). CYP1A2 is increased to a lesser extent together with glutathione-S-transferase (GST) down-regulation. Dig 1, non cytotoxic and not inducing caspases by itself, is able to prevent Roundup-induced cell death in a time-dependant manner with an important efficiency of up to 89%, within 48 h. In addition, we evidenced that it prevents Caspases 3/7 activation and CYP3A4 enhancement, and not GST reduction, but in turn it slightly inhibited CYP2C9 when added before Roundup. Roundup is able to provoke intracellular disruption in hepatic cell lines at different levels, but a mixture of medicinal plant extracts Dig1 can protect to some extent human cell lines against this pollutants. All this system constitutes a tool for studying liver intoxication and detoxification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979644"}
{"pmid": "20979645", "title": "Presence of human herpes virus 6 (HHV6) in pediatric lymphomas: impact on clinical course and association with cytomegalovirus infection.", "content": "Presence of human herpes virus 6 (HHV6) in pediatric lymphomas: impact on clinical course and association with cytomegalovirus infection. Activation of herpes virus 6 (HHV6) has seen in Hodgkin's and non-Hodgkin's Lymphoma (HL&NHL) as a result of lymphoma associated immunosuppression. Multiple studies have suggested an association between both HHV6 and cytomegalovirus CMV for development of CMV disease affecting the pathogenesis of lymphoma. Therefore, this study investigated the frequency of HHV6, its impact on clinical manifestations of lymphoma and its possible association with risk for development of CMV infection in pediatric lymphoma patients. Presence of HHV6 DNA and CMV DNA was investigated by PCR assay in both WBC's and plasma samples from 50 patients diagnosed with HL or NHL. CMV antibody titer was also determined in sera obtained from each patient. Twenty apparently healthy siblings were used as a control group. In a study group of 50 patients diagnosed with HL or NHL, 23/50 (46%) were found to be positive for herpes virus DNA (HHV6 or CMV) in WBC's or plasma by PCR assay and this was significantly higher than its presence in the pediatric control group 2/20 (10%) (p = 0.005). Ten out of these 23 (43%) were found to have active CMV infection. Fifty six percent of patients with CMV infection were found among NHL cases with B- subtype. The presence of both herpes viruses DNA was significantly associated with more frequent episodes of febrile neutropenia (median 3 episodes), absolute neutrophil count (< 0.8), lymphocytes (< 0.5), and low hemoglobin level (< 9.1), (p < 0.05). The presence of HHV6 can be considered as a predicting indicator of cellular immunosuppression preceding the onset of CMV infection which may result in a severe outcome among pediatric lymphoma patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979645"}
{"pmid": "20979646", "title": "Soluble ephrin a1 is necessary for the growth of HeLa and SK-BR3 cells.", "content": "Soluble ephrin a1 is necessary for the growth of HeLa and SK-BR3 cells. Ephrin A1 (EFNA1) is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. In malignancy, the precise role of EFNA1 and its preferred receptor, EPHA2, is controversial. Several studies have found that EFNA1 may suppress EPHA2-mediated oncogenesis, or enhance it, depending on cell type and context. However, little is known about the conditions that influence whether EFNA1 promotes or suppresses tumorigenicity. EFNA1 exists in a soluble form as well as a glycophosphatidylinositol (GPI) membrane attached form. We investigated whether the contradictory roles of EFNA1 in malignancy might in part be related to the existence of both soluble and membrane attached forms of EFNA1 and potential differences in the manner in which they interact with EPHA2. Using a RNAi strategy to reduce the expression of endogenous EFNA1 and EPHA2, we found that both EFNA1 and EPHA2 are required for growth of HeLa and SK-BR3 cells. The growth defects could be rescued by conditioned media from cells overexpressing soluble EFNA1. Interestingly, we found that overexpression of the membrane attached form of EFNA1 suppresses growth of HeLa cells in 3D but not 2D. Knockdown of endogenous EFNA1, or overexpression of full-length EFNA1, resulted in relocalization of EPHA2 from the cell surface to sites of cell-cell contact. Overexpression of soluble EFNA1 however resulted in more EPHA2 distributed on the cell surface, away from cell-cell contacts, and promoted the growth of HeLa cells. We conclude that soluble EFNA1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979646"}
{"pmid": "20979647", "title": "Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin.", "content": "Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin. Only a few studies have addressed the molecular pathways specifically involved in carcinogenesis of the distal colon and rectum. We aimed to identify potential differences among genetic alterations in distal colon and rectal carcinomas as compared to cancers arising elsewhere in the large bowel. Constitutional and tumor DNA from a test series of 37 patients with rectal and 25 patients with sigmoid carcinomas, previously analyzed for microsatellite instability (MSI), was studied for BAX, IGF2R, TGFBR2, MSH3, and MSH6 microsatellite sequence alterations, BRAF and KRAS mutations, and MLH1 promoter methylation. The findings were then compared with those of an independent validation series consisting of 36 MSI-H carcinomas with origin from each of the large bowel regions. Immunohistochemical and germline mutation analyses of the mismatch repair system were performed when appropriate. In the test series, IGFR2 and BAX mutations were present in one and two out of the six distal MSI-H carcinomas, respectively, and no mutations were detected in TGFBR2, MSH3, and MSH6. We confirmed these findings in the validation series, with TGFBR2 and MSH3 microsatellite mutations occurring less frequently in MSI-H rectal and sigmoid carcinomas than in MSI-H colon carcinomas elsewhere (P = 0.00005 and P = 0.0000005, respectively, when considering all MSI-carcinomas of both series). No MLH1 promoter methylation was observed in the MSI-H rectal and sigmoid carcinomas of both series, as compared to 53% found in MSI-H carcinomas from other locations (P = 0.004). KRAS and BRAF mutational frequencies were 19% and 43% in proximal carcinomas and 25% and 17% in rectal/sigmoid carcinomas, respectively. The mechanism and the pattern of genetic changes driving MSI-H carcinogenesis in distal colon and rectum appears to differ from that occurring elsewhere in the colon and further investigation is warranted both in patients with sporadic or hereditary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979647"}
{"pmid": "20979648", "title": "Elasticity-based determination of isovolumetric phases in the human heart.", "content": "Elasticity-based determination of isovolumetric phases in the human heart. BACKGROUND/MOTIVATION: To directly determine isovolumetric cardiac time intervals by magnetic resonance elastography (MRE) using the magnitude of the complex signal for deducing morphological information combined with the phase of the complex signal for tension-relaxation measurements. Thirty-five healthy volunteers and 11 patients with relaxation abnormalities were subjected to transthoracic wave stimulation using vibrations of approximately 25 Hz. A k-space-segmented, ECG-gated gradient-recalled echo steady-state sequence with a 500-Hz bipolar motion-encoding gradient was used for acquiring a series of 360 complex images of a short-axis view of the heart at a frame rate of less than 5.2 ms. Magnitude images were employed for measuring the cross-sectional area of the left ventricle, while phase images were used for analyzing the amplitudes of the externally induced waves. The delay between the decrease in amplitude and onset of ventricular contraction was determined in all subjects and assigned to the time of isovolumetric tension. Conversely, the delay between the increase in wave amplitude and ventricular dilatation was used for measuring the time of isovolumetric elasticity relaxation. Wave amplitudes decreased during systole and increased during diastole. The variation in wave amplitude occurred ahead of morphological changes. In healthy volunteers the time of isovolumetric elasticity relaxation was 75 ± 31 ms, which is significantly shorter than the time of isovolumetric tension of 136 ± 36 ms (P < 0.01). In patients with relaxation abnormalities (mild diastolic dysfunction, n = 11) isovolumetric elasticity relaxation was significantly prolonged, with 133 ± 57 ms (P < 0.01), whereas isovolumetric tension time was in the range of healthy controls (161 ± 45 ms; P = 0.053). The complex MRE signal conveys complementary information on cardiac morphology and elasticity, which can be combined for directly measuring isovolumetric tension and elasticity relaxation in the human heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979648"}
{"pmid": "20979649", "title": "Family physicians' experiences when collaborating with district nurses in home care-based medical treatment. A grounded theory study.", "content": "Family physicians' experiences when collaborating with district nurses in home care-based medical treatment. A grounded theory study. This article concerns Swedish family physicians' (FPs) experiences collaborating with district nurses (DNs) when the DNs provide medical treatment for home care patients. The aim was to develop a model to illuminate this process from the FPs' perspective. Semi-structured interviews were conducted with 13 FPs concerning one of their patients with home care by a DN. The interview focused on one patient's treatment and care by different care providers and the collaboration among them. Grounded theory methodology (GTM) was used in the analyses. It was essential for FPs to collaborate with and rely on DNs in the medical treatment of home care patients. According to the FPs, factors such as the disease, FPs' working conditions and attitude determined how much of the initiative in this treatment FPs retained or left to DNs. Depending on the circumstances, two different roles were adopted by the individual FPs: medical conductors who retain the initiative and medical consultants who leave the initiative to DNs. Factors as the disease, DNs' attitudes towards collaboration and DNs' working conditions influenced whether or not the FPs felt that grounds for relying on DNs were satisfactory. Regardless of the role of the FP, conditions for medical treatment were judged by the FPs to be good enough when the grounds for relying on the DN were satisfactory and problematic when they were not. In the role of conductor, the FP will identify when the grounds for relying on the DN are unsatisfactory and be able to take action, but in the role of consultant the FP will not detect this, leaving home care patients without appropriate support. Only when there are satisfactory grounds for relying on the DN, will conditions for providing home care medical treatment be good enough when the FP adopts a consultative role.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979649"}
{"pmid": "20979650", "title": "Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritis.", "content": "Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritis. The association between proinflammatory cytokine gene polymorphisms and gastric diseases related to Helicobacter pylori varies by population and geographic area.Our objective was to determine if the IL-1B -511 T>C and -31 C>T polymorphisms and H. pylori vacA genotypes are associated with risk of chronic gastritis and gastric ulcer in a Mexican population. We conducted endoscopic studies in 128 patients with symptoms of dyspepsia. We took two biopsies from the body, antrum, or ulcer edge from each patient, and classified our histopathological findings according to the Sydney System. H. pylori infection and vacA genotyping were accomplished via PCR from total DNA of the gastric biopsies. We confirmed the presence of anti-H. pylori serum IgG and IgM in 102 control subjects. In both case subjects and control subjects, the IL-1B -511 T>C polymorphism was genotyped by PCR-RFLPs and the IL-1B -31 C>T polymorphism was genotyped by pyrosequencing. Sixty-two point seven (62.7%) of the 102 control subjects were H. pylori-seropositive. Among the case subjects, 100 were diagnosed with chronic gastritis and 28 with gastric ulcer. We found that 77% of the patients with chronic gastritis and 85.7% of the patients with gastric ulcer were H. pylori-positive. The predominant H. pylori genotype was vacA s1m1 (58.4%) and the most frequent subtype was vacA s1. The -511 TC, (rs16944 -511 T>C) genotype and the -511C allele were associated with chronic gastritis (OR = 3.1, 95% CI = 1.4-6.8 and OR = 3.0, 95% CI = 1.4-6.0, respectively). The subjects carrying -31T (rs1143627 -31 C>T) were found to be at a higher risk of having chronic gastritis (OR = 2.8, 95% CI = 1.3-5.8). The IL-1B -511C/-31T haplotype was associated with chronic gastritis (OR = 2.1, 95% CI = 1.2-3.8) but not with gastric ulcer. The H. pylori vacA genotypes identified herein were similar to those reported for other regions of Mexico. The vacA s1m1 genotype was not associated with gastric ulcer. In the southern Mexican population, the IL-1B -511C and -31T alleles and the -511C/-31T and -511T/-31T haplotypes are associated with increased risk of chronic gastritis and gastric ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979650"}
{"pmid": "20979651", "title": "Targeting the hotspots: investigating spatial and demographic variations in HIV infection in small communities in South Africa.", "content": "Targeting the hotspots: investigating spatial and demographic variations in HIV infection in small communities in South Africa. In South Africa, the severity of the HIV/AIDS epidemic varies according to geographical location; hence, localized monitoring of the epidemic would enable more effective prevention strategies. Our objectives were to assess the core areas of HIV infection in KwaZulu-Natal, South Africa, using epidemiological data among sexually active women from localized communities. A total of 5753 women from urban, peri-rural and rural communities in KwaZulu-Natal were screened from 2002 to 2005. Each participant was geocoded using a global information system, based on residence at time of screening. The Spatial Scan Statistics programme was used to identify areas with disproportionate excesses in HIV prevalence and incidence. This study identified three hotspots with excessively high HIV prevalence rates of 56%, 51% and 39%. A total of 458 sexually active women (19% of all cases) were included in these hotspots, and had been exclusively recruited by the Botha's Hill (west of Durban) and Umkomaas (south of Durban) clinic sites. Most of these women were Christian and Zulu-speaking. They were also less likely to be married than women outside these areas (12% vs. 16%, p = 0.001) and more likely to have sex more than three times a week (27% vs. 20%, p < 0.001) and to have had more than three sexual partners (55% vs. 45%, p < 0.001). Diagnosis of genital herpes simplex virus type 2 was also more common in the hotspots. This study also identified areas of high HIV incidence, which were broadly consistent with those with high prevalence rates. Geographic excesses of HIV infections at rates among the highest in the world were detected in certain rural communities of Durban, South Africa. The results reinforce the inference that risk of HIV infection is associated with definable geographical areas. Localized monitoring of the epidemic is therefore essential for more effective prevention strategies--and particularly urgent in a region such as KwaZulu-Natal, where the epidemic is particularly rampant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979651"}
{"pmid": "20979654", "title": "Defensin alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients.", "content": "Defensin alpha 6 (DEFA 6) overexpression threshold of over 60 fold can distinguish between adenoma and fully blown colon carcinoma in individual patients. It is known that alpha-defensin expression is enhanced in colon cancer. However, the expression of human alpha defensin 6 (DEFA 6) in earlier stages, such as adenoma, has so far not yet been studied in a patient resolved manner. By using quantitative Real Time-PCR, the gene expression pattern of DEFA 1-3 and DEFA 6 was analyzed in tissue of different stages of carcinogenesis, derived from colorectal cancer patients. In addition to paired normal and tumor tissue, matched normal near tumor and adenoma tissue samples were examined. The median gene expression of human defensin alpha 6 (DEFA 6) has been found to be moderately increased (~ 5 fold) in tumor samples derived from individuals with colorectal cancer (CRC) when compared to their normal counterparts. However, when the data were analyzed in a patient-wise manner, a large expression variation among individual patients is found, making the use of DEFA 6 for individual diagnosis of fully blown colon carcinoma difficult. Surprisingly, in adenoma the gene expression analysis revealed a 100 fold increased median expression of DEFA 6 relative to normal colon tissue. 13/18 samples had an individual overexpression of more than 60 fold in adenoma but only 3/17 in carcinoma. In each of the individual patients, at least either the adenoma or the carcinoma showed strong DEFA 6 overexpression. We suggest that the expression of DEFA 6 preferably can be used as a potential diagnostic marker for adenoma and not as a marker for fully blown carcinoma. This is supported by the fact that DEFA 6 is a downstream target of the Wnt pathway, which is mutational active during the earliest stage of cancer development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979654"}
{"pmid": "20979655", "title": "Analysis of a tobacco vector and its actions in china: the activities of japan tobacco.", "content": "Analysis of a tobacco vector and its actions in china: the activities of japan tobacco.  Japan Tobacco (JT) is the third largest tobacco company in the world, and China, the world's largest tobacco consumer, is one of the most important targets for JT. To provide information for tobacco control, we reviewed and analyzed JT and its tactics and strategies in the Chinese market mainly by systematic examination of documents which are made available in the University of California, San Francisco Legacy Tobacco Documents Library. As a result, JT has had a special interest to expand sales of its cigarettes in the Chinese market.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979655"}
{"pmid": "20979653", "title": "Expression of connexin genes in the human retina.", "content": "Expression of connexin genes in the human retina. Gap junction channels allow direct metabolically and electrical coupling between adjacent cells in various mammalian tissues. Each channel is composed of 12 protein subunits, termed connexins (Cx). In the mouse retina, Cx43 could be localized mostly between astroglial cells whereas expression of Cx36, Cx45 and Cx57 genes has been detected in different neuronal subtypes. In the human retina, however, the expression pattern of connexin genes is largely unknown. Northern blot hybridizations, RT-PCR as well as immunofluorescence analyses helped to explore at least partially the expression pattern of the following human connexin genes GJD2 (hCx36), GJC1 (hCx45), GJA9 (hCx59) and GJA10 (hCx62) in the human retina. Here we report that Northern blot hybridization signals of the orthologuous hCx36 and hCx45 were found in human retinal RNA. Immunofluorescence signals for both connexins could be located in both inner and outer plexiform layer (IPL, OPL). Expression of a third connexin gene denoted as GJA10 (Cx62) was also detected after Northern blot hybridization in the human retina. Interestingly, its gene structure is similar to that of Gja10 (mCx57) being expressed in mouse horizontal cells. RT-PCR analysis suggested that an additional exon of about 25 kb further downstream, coding for 12 amino acid residues, is spliced to the nearly complete reading frame on exon2 of GJA10 (Cx62). Cx59 mRNA, however, with high sequence identity to zebrafish Cx55.5 was only weakly detectable by RT-PCR in cDNA of human retina. In contrast to the neuron-expressed connexin genes Gjd2 coding for mCx36, Gjc1 coding for mCx45 and Gja10 coding for mCx57 in the mouse, a subset of 4 connexin genes, including the unique GJA9 (Cx59) and GJA10 (Cx62), could be detected at least as transcript isoforms in the human retina. First immunofluorescence analyses revealed a staining pattern of hCx36 and hCx45 expression both in the IPL and OPL, partially reminiscent to that in the mouse, although additional post-mortem material is needed to further explore their sublamina-specific distribution. Appropriate antibodies against Cx59 and Cx62 protein will clarify expression of these proteins in future studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979653"}
{"pmid": "20979652", "title": "Treatment options for patients with triple-negative breast cancer.", "content": "Treatment options for patients with triple-negative breast cancer. Breast cancer is a heterogeneous disease composed of different subtypes, characterized by their different clinicopathological characteristics, prognoses and responses to treatment. In the past decade, significant advances have been made in the treatment of breast cancer sensitive to hormonal treatments, as well as in patients whose malignant cells overexpress or amplify HER2. In contrast, mainly due to the lack of molecular targets, little progress has been made in the treatment of patients with triple-negative breast cancer. Recent improved understanding of the natural history, pathophysiology, and molecular features of triple-negative breast cancers have provided new insights into management and therapeutic strategies for women affected with this entity. Ongoing and planned translational clinical trials are likely to optimize and improve treatment of women with this disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979652"}
{"pmid": "20979656", "title": "Can near real-time monitoring of emergency department diagnoses facilitate early response to sporadic meningococcal infection?--prospective and retrospective evaluations.", "content": "Can near real-time monitoring of emergency department diagnoses facilitate early response to sporadic meningococcal infection?--prospective and retrospective evaluations. Meningococcal infection causes severe, rapidly progressing illness and reporting of cases is mandatory in New South Wales (NSW), Australia. The NSW Department of Health operates near real-time Emergency Department (ED) surveillance that includes capture and statistical analysis of clinical preliminary diagnoses. The system can provide alerts in response to specific diagnoses entered in the ED computer system. This study assessed whether once daily reporting of clinical diagnoses of meningococcal infection using the ED surveillance system provides an opportunity for timelier public health response for this disease. The study involved a prospective and retrospective component. First, reporting of ED diagnoses of meningococcal infection from the ED surveillance system prospectively operated in parallel with conventional surveillance which requires direct telephone reporting of this scheduled medical condition to local public health authorities by hospitals and laboratories when a meningococcal infection diagnosis is made. Follow-up of the ED diagnoses determined whether meningococcal infection was confirmed, and the time difference between ED surveillance report and notification by conventional means. Second, cases of meningococcal infection reported by conventional surveillance during 2004 were retrospectively matched to ED visits to determine the sensitivity and positive predictive value (PPV) of ED surveillance. During the prospective evaluation, 31 patients were diagnosed with meningococcal infection in participating EDs. Of these, 12 had confirmed meningococcal disease, resulting in a PPV of 38.7%. All confirmed cases were notified earlier to public health authorities by conventional reporting.Of 149 cases of notified meningococcal disease identified retrospectively, 130 were linked to an ED visit. The sensitivity and PPV of the ED diagnosis for meningococcal infection was 36.2% and 36.7%, respectively. Based on prospective evaluation, it is reassuring that existing mechanisms for reporting meningococcal infection perform well and are timely. The retrospective evaluation found low sensitivity and PPV of ED diagnoses for meningococcal disease. Even if more rapid forwarding of ED meningococcal diagnoses to public health authorities were possible, the low sensitivity and PPV do not justify this. In this study, use of an ED surveillance system to augment conventional surveillance of this scheduled medical condition did not demonstrate a benefit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979656"}
{"pmid": "20979659", "title": "Long-term glycine propionyl-l-carnitine supplemention and paradoxical effects on repeated anaerobic sprint performance.", "content": "Long-term glycine propionyl-l-carnitine supplemention and paradoxical effects on repeated anaerobic sprint performance. It has been demonstrated that acute GPLC supplementation produces enhanced anaerobic work capacity with reduced lactate production in resistance trained males. However, it is not known what effects chronic GPLC supplementation has on anaerobic performances or lactate clearance. The purpose of this study was to examine the long-term effects of different dosages of GPLC supplementation on repeated high intensity stationary cycle sprint performance. Forty-five resistance trained men participated in a double-blind, controlled research study. All subjects completed two testing sessions, seven days apart, 90 minutes following oral ingestion of either 4.5 grams GPLC or 4.5 grams cellulose (PL), in randomized order. The exercise testing protocol consisted of five 10-second Wingate cycle sprints separated by 1-minute active recovery periods. Following completion of the second test session, the 45 subjects were randomly assigned to receive 1.5 g, 3.0 g, or 4.5 g GPLC per day for a 28 day period. Subjects completed a third test session following the four weeks of GPLC supplementation using the same testing protocol. Values of peak power (PP), mean power (MP) and percent decrement of power (DEC) were determined per bout and standardized relative to body mass. Heart rate (HR) and blood lactate (LAC) were measured prior to, during and following the five sprint bouts. There were no significant effects of condition or significant interaction effects detected for PP and MP. However, results indicated that sprint bouts three, four and five produced 2 - 5% lower values of PP and 3 - 7% lower values of MP with GPLC at 3.0 or 4.5 g per day as compared to baseline values. Conversely, 1.5 g GPLC produced 3 - 6% higher values of PP and 2 -5% higher values of MP compared with PL baseline values. Values of DEC were significantly greater (15-20%) greater across the five sprint bouts with 3.0 g or 4.5 g GPLC, but the 1.5 g GPLC supplementation produced DEC values -5%, -3%, +4%, +5%, and +2% different from the baseline PL values. The 1.5 g group displayed a statistically significant 24% reduction in net lactate accumulation per unit power output (p < 0.05). The effects of GPLC supplementation on anaerobic work capacity and lactate accumulation appear to be dosage dependent. Four weeks of GPLC supplementation at 3.0 and 4.5 g/day resulted in reduced mean values of power output with greater rates of DEC compared with baseline while 1.5 g/day produced higher mean values of MP and PP with modest increases of DEC. Supplementation of 1.5 g/day also produced a significantly lower rate of lactate accumulation per unit power output compared with 3.0 and 4.5 g/day. In conclusion, GPLC appears to be a useful dietary supplement to enhance anaerobic work capacity and potentially sport performance, but apparently the dosage must be determined specific to the intensity and duration of exercise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979659"}
{"pmid": "20979658", "title": "Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice.", "content": "Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice. Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme catabolism, has been reported to have potential antioxidant properties. However, the role of HO-1 on hepatocyte apoptosis remains unclear. We aim to elucidate the effects of HO-1 on oxidative stress related hepatocellular apoptosis in nutritional steatohepatitis in mice. C57BL/6J mice were fed with methionine-choline deficient (MCD) diet for four weeks to induce hepatic steatohepatitis. HO-1 chemical inducer (hemin), HO-1 chemical inhibitor zinc protoporphyrin IX (ZnPP-IX) and/or adenovirus carrying HO-1 gene (Ad-HO-1) were administered to mice, respectively. Hepatocyte apoptosis was evaluated by terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay, the mRNA and protein expression of apoptosis related genes were assayed by quantitative real-time PCR and Western blot. Hepatocyte signs of oxidative related apoptotic injury were presented in mice fed with MCD diet for 4 weeks. Induction of HO-1 by hemin or Ad-HO-1 significantly attenuated the severity of liver histology, which was associated with decreased hepatic lipid peroxidation content, reduced number of apoptotic cells by TUNEL staining, down-regulated expression of pro-apoptosis related genes including Fas/FasL, Bax, caspase-3 and caspase-9, reduced expression of cytochrome p4502E1 (CYP2E1), inhibited cytochrome c (Cyt-c) release, and up-regulated expression of anti-apoptosis gene Bcl-2. Whereas, inhibition of HO-1 by ZnPP-IX caused oxidative stress related hepatic injury, which concomitant with increased number of TUNEL positive cells and up-regulated expression of pro-apoptosis related genes. The present study provided evidences for the protective role of HO-1 in preventing nutritional steatohepatitis through suppressing hepatocyte apoptosis in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979658"}
{"pmid": "20979657", "title": "Effects of creatine and β-guanidinopropionic acid and alterations in creatine transporter and creatine kinases expression in acute seizure and chronic epilepsy models.", "content": "Effects of creatine and β-guanidinopropionic acid and alterations in creatine transporter and creatine kinases expression in acute seizure and chronic epilepsy models. In order to confirm the roles of creatine (Cr) in epilepsy, we investigated the anti-convulsive effects of Cr, creatine transporter (CRT) and creatine kinases (CKs) against chemical-induced acute seizure activity and chronic epileptic seizure activity. Two hr after pilocarpine (PILO)-seizure induction, ubiquitous mitochondrial CK (uMtCK) immunoreactivity was unaltered as compared to control level. However, brain-type cytoplasm CK (BCK) immunoreactivity was decreased to 70% of control level. CRT immunoreactivity was decreased to 60% of control level. Following Cr or Tat-CK treatment, uMtCK or CRT immunoreactivity was unaffected, while BCK immunoreactivity in Cr treated group was increased to 3.6-fold of control levels. β-Guanidinopropionic acid (GPA, a competitive CRT inhibitor) reduced BCK and CRT expression. In addition, Cr and tat-BCK treatment delayed the beginning of seizure activity after PILO injection. However, GPA treatment induced spontaneous seizure activity without PILO treatment. In chronic epilepsy rats, both uMtCK and CRT immunoreactivities were reduced in the hippocampus. In contrast, BCK immunoreactivity was similar to that observed in control animals. Cr-, GPA and tat-BCK treatment could not change EEG. Cr/CK circuit may play an important role in sustaining or exacerbating acute seizure activity, but not chronic epileptic discharge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979657"}
{"pmid": "20979660", "title": "A miniaturized sandwich immunoassay platform for the detection of protein-protein interactions.", "content": "A miniaturized sandwich immunoassay platform for the detection of protein-protein interactions. Analysis of protein-protein interactions (PPIs) is a valuable approach for the characterization of huge networks of protein complexes or proteins of unknown function. Co-immunoprecipitation (coIP) using affinity resins coupled to protein A/G is the most widely used method for PPI detection. However, this traditional large scale resin-based coIP is too laborious and time consuming. To overcome this problem, we developed a miniaturized sandwich immunoassay platform (MSIP) by combining antibody array technology and coIP methods. Based on anti-FLAG antibody spotted aldehyde slides, MSIP enables simple, rapid and large scale detection of PPIs by fluorescent labeling anti-myc antibody. By analyzing well-known interacting and non-interacting protein pairs, MSIP was demonstrated to be highly accurate and reproducible. Compared to traditional resin-based coIP, MSIP results in higher sensitivity and enhanced throughput, with the additional benefit of digital read-outs. In addition, MSIP was shown to be a highly useful validation platform to confirm PPI candidates that have been identified from yeast two hybrid systems. In conclusion, MSIP is proved to be a simple, cost-saving and highly efficient technique for the comprehensive study of PPIs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979660"}
{"pmid": "20979662", "title": "Factors influencing inpatient rehabilitation length of stay following revision hip replacements: a retrospective study.", "content": "Factors influencing inpatient rehabilitation length of stay following revision hip replacements: a retrospective study. The annual incidence of revision hip replacements has increased in both Canada and United States, particularly in younger adults. Patients following revision hip replacements often require longer hospital length of stay (LOS) but little is known about predictors of inpatient rehabilitation LOS in this group of patients. The purpose of this study was to evaluate the socio-demographic, pre-surgery, surgery and post-surgery related factors that might influence rehabilitation LOS of inpatients following revision hip replacements. This study included inpatients discharged from a musculoskeletal ward between 2002 and 2006 following rehabilitation revision hip replacement. Data sources included the National Reporting System, a standardized, provincial administrative database and augmented by chart abstraction. The collected elements included the outcome LOS and the following independent variables: age, sex, support at home, environmental barriers, language barrier, number of revision surgeries on the affected hip, comorbidity, previous orthopaedic surgeries in the lower extremities (L/ES), the hip component(s) revised, weight-bearing status, hemoglobin level, complications, days lapsed from surgery to rehabilitation admission and admission scores on the Functional Independence Measure (FIM). Simple linear regression was used to take forward any predictors significant at p < .10 level. Variables that satisfied the significance level were grouped in blocks and entered for regression analyses. The 275 patients in this sample had a mean age of 69 years; 62% were female and the mean LOS was 29.6 days. Statistically significant predictors of longer LOS were low admission FIM score, female sex, revision of only the femoral component, 2 or more prior surgeries in the L/Es and 2 or more hip revisions (redo revision). The final model explained 28% of variance in inpatient LOS. A score of 9-14 points lower in admission FIM, female sex, revision of only the femoral component, prior surgeries in the L/Es and redo hip revision are all independent factors associated with 4-6 days longer LOS. These results may facilitate an understanding of bed flow. Additionally, patients with one or a combination of the above characteristics may benefit from enhanced care plans that facilitate achievement of rehabilitation goals for discharge home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979662"}
{"pmid": "20979661", "title": "Z-360, a novel therapeutic agent for pancreatic cancer, prevents up-regulation of ephrin B1 gene expression and phosphorylation of NR2B via suppression of interleukin-1 β production in a cancer-induced pain model in mice.", "content": "Z-360, a novel therapeutic agent for pancreatic cancer, prevents up-regulation of ephrin B1 gene expression and phosphorylation of NR2B via suppression of interleukin-1 β production in a cancer-induced pain model in mice. Z-360 is an orally active cholecystokinin-2 (CCK2)/gastrin receptor antagonist currently under development as a therapeutic drug for pancreatic cancer. It was previously reported that Z-360 treatment in combination with gemcitabine prolonged the survival period in a lethal pancreatic cancer xenograft model in mice. In a phase Ib/IIa clinical study, Z-360 treatment displayed a trend of reduced pain in patients with advanced pancreatic cancer in combination with gemcitabine including analgesics such as opioids. Here, we investigated the mechanism of analgesic action of Z-360 in a severe cancer-induced pain model in mice, which is considered to be opioid-resistant, by examining ephrin B1 gene expression, N-methyl-D-aspartate receptor NR2B subunit phosphorylation, and interleukin-1β (IL-1β) production. In a mouse model of cancer-induced pain, ephrin B1 gene expression in dorsal root ganglia (DRGs) and the phosphorylation of NR2B in the spinal cord were induced. Z-360 treatment inhibited both ephrin B1 gene expression and the phosphorylation of NR2B. In addition, IL-1β production increased in the cancer-inoculated hind paw of mice, but could be suppressed by treatment with Z-360. Moreover, we observed that the CCK1 receptor antagonist devazepide similarly suppressed up-regulation of ephrin B1 gene expression and IL-1β production, and that the intraperitoneal injection of sulfated CCK-8 induced the production of IL-1β in the cancer-inoculated region. We have identified a novel pain cascade, in which IL-1β production in cancer-inoculated regions induces ephrin B1 gene expression in DRGs and then ephrin B1 enhances the tyrosine phosphorylation of NR2B via Eph B receptor in the spinal cord. Notably, Z-360 relieves cancer-induced pain by preventing this pain cascade through the suppression of IL-1β production, likely via the blockade of CCK1 receptor. The pre-clinical results presented here support the analgesic action of Z-360 in pancreatic cancer patients with severe, opioid-resistant pain. Pre-clinical and clinical results have demonstrated that Z-360 combined with gemcitabine represents a promising pancreatic cancer therapy approach with characteristic analgesic effects in addition to the prolongation of survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979661"}
{"pmid": "20979664", "title": "Determination of the differentiation capacities of murines' primary mononucleated cells and MC3T3-E1 cells.", "content": "Determination of the differentiation capacities of murines' primary mononucleated cells and MC3T3-E1 cells. The main morphological features of primitive cells, such as stem and progenitor cells, are that these cells consists only one nucleus. The main purpose of this study was to determine the differentiation capacities of stem and progenitor cells. This study was performed using mononucleated cells originated from murine peripheral blood and MC3T3-E1 cells. Three approaches were used to determine their differentiation capacities: 1) Biochemical assays, 2) Gene expression analysis, and 3) Morphological observations. We found that both cells were able to differentiate into mature osteoblasts, as assayed by ALP activity. RT-PCR analysis showed the activation of the Opn gene after osteoblast differentiation. Morphological observations of both cells revealed the formation of black or dark-brown nodules after von Kossa staining. Nevertheless, only mononucleated cells showed the significant increase in TRAP activity characteristic of mature osteoclasts. The osteoclast-specific CatK gene was only upregulated in mononucleated cells. Morphological observations indicated the existence of multinucleated osteoclasts. Sca-1 was activated only in undifferentiated mononucleated cells, indicating that the cells were hematopoietic stem cells. In both cell lines, the housekeeping Gapdh gene was activated before and after differentiation. The isolated mononucleated cells were able to differentiate into both osteoblasts and osteoclasts; indicating that they are stem cells. On the other hand, MC3T3-E1 cells can only differentiate into osteoblasts; a characteristic of progenitor cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979664"}
{"pmid": "20979663", "title": "Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia.", "content": "Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia. Rearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and resistance to glucocorticoids (GCs). We have recently observed that GC resistance in T-ALL cell lines is associated with a proliferative metabolism and reduced expression of MLL. In this study we have further explored the relationship between MLL status and GC sensitivity. Negative correlation of MLL expression with GC resistance in 15 T-ALL cell lines was confirmed by quantitative RT-PCR. The absence of MLL-rearrangements suggested that this relationship represented expression of wild-type MLL. Analysis of MLL expression patterns revealed a negative relationship with cellular metabolism, proliferation and anti-apoptotic transcriptional networks. In silico analysis of published data demonstrated that reduced levels of MLL mRNA are associated with relapse and prednisolone resistance in T-ALL patients and adverse clinical outcome in children with MLL-rearranged ALL. RNAi knockdown of MLL expression in T-ALL cell lines significantly increased resistance to dexamethasone and gamma irradiation indicating an important role for wild-type MLL in the control of cellular apoptosis. The data suggests that reduced expression of wild-type MLL can contribute to GC resistance in ALL patients both with and without MLL-translocations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979663"}
{"pmid": "20979665", "title": "Decoding hand movement velocity from electroencephalogram signals during a drawing task.", "content": "Decoding hand movement velocity from electroencephalogram signals during a drawing task. Decoding neural activities associated with limb movements is the key of motor prosthesis control. So far, most of these studies have been based on invasive approaches. Nevertheless, a few researchers have decoded kinematic parameters of single hand in non-invasive ways such as magnetoencephalogram (MEG) and electroencephalogram (EEG). Regarding these EEG studies, center-out reaching tasks have been employed. Yet whether hand velocity can be decoded using EEG recorded during a self-routed drawing task is unclear. Here we collected whole-scalp EEG data of five subjects during a sequential 4-directional drawing task, and employed spatial filtering algorithms to extract the amplitude and power features of EEG in multiple frequency bands. From these features, we reconstructed hand movement velocity by Kalman filtering and a smoothing algorithm. The average Pearson correlation coefficients between the measured and the decoded velocities are 0.37 for the horizontal dimension and 0.24 for the vertical dimension. The channels on motor, posterior parietal and occipital areas are most involved for the decoding of hand velocity. By comparing the decoding performance of the features from different frequency bands, we found that not only slow potentials in 0.1-4 Hz band but also oscillatory rhythms in 24-28 Hz band may carry the information of hand velocity. These results provide another support to neural control of motor prosthesis based on EEG signals and proper decoding methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979665"}
{"pmid": "20979666", "title": "Mcm10 proteolysis initiates before the onset of M-phase.", "content": "Mcm10 proteolysis initiates before the onset of M-phase. Mcm10 protein is essential for initiation and elongation phases of replication. Human cells proteolyze Mcm10 during mitosis, presumably to ensure a single round of replication. It has been proposed that anaphase promoting complex ubiquitinates Mcm10 in late M and early G1 phases. In contrast to the previous work, we report that the degradation of Mcm10 is initiated at the onset of mitosis. Immunoblotting and immunofluorescence assays display that Mcm10 levels are low in all phases of mitosis. We report that Mcm10 degradation is not dependent on anaphase promoting complex. Further, the proteolysis in M-phase can be independently mediated by non-overlapping regions of Mcm10, apparently employing a redundant mechanism to ensure downregulation. It is believed that the proteolysis of Mcm10 during mitosis is a vital mechanism to prevent aberrant initiation of replication and the present study describes the regulation of Mcm10 during this phase of the cell-cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979666"}
{"pmid": "20979668", "title": "The therapeutic potential of a venomous lizard: the use of glucagon-like peptide-1 analogues in the critically ill.", "content": "The therapeutic potential of a venomous lizard: the use of glucagon-like peptide-1 analogues in the critically ill. Glucagon-like peptide-1 (GLP-1), a principal mediator of the postprandial insulinotropic response in health, has a half-life of minutes. The saliva of the Gila monster contains exendin-4, a structural analogue of human GLP-1, but with a much longer half-life. A synthetic preparation of exendin-4, exenatide, is suitable for human use and effectively lowers glucose in ambulant type 2 diabetic patients. When compared with insulin, exenatide therapy is associated with a reduction in hypoglycaemic episodes and postprandial glycaemic excursions in this group. Accordingly, GLP-1 analogues are appealing therapies for hyperglycaemia in the critically ill patient and warrant further study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979668"}
{"pmid": "20979667", "title": "Conserved and variable correlated mutations in the plant MADS protein network.", "content": "Conserved and variable correlated mutations in the plant MADS protein network. Plant MADS domain proteins are involved in a variety of developmental processes for which their ability to form various interactions is a key requisite. However, not much is known about the structure of these proteins or their complexes, whereas such knowledge would be valuable for a better understanding of their function. Here, we analyze those proteins and the complexes they form using a correlated mutation approach in combination with available structural, bioinformatics and experimental data. Correlated mutations are affected by several types of noise, which is difficult to disentangle from the real signal. In our analysis of the MADS domain proteins, we apply for the first time a correlated mutation analysis to a family of interacting proteins. This provides a unique way to investigate the amount of signal that is present in correlated mutations because it allows direct comparison of mutations in various family members and assessing their conservation. We show that correlated mutations in general are conserved within the various family members, and if not, the variability at the respective positions is less in the proteins in which the correlated mutation does not occur. Also, intermolecular correlated mutation signals for interacting pairs of proteins display clear overlap with other bioinformatics data, which is not the case for non-interacting protein pairs, an observation which validates the intermolecular correlated mutations. Having validated the correlated mutation results, we apply them to infer the structural organization of the MADS domain proteins. Our analysis enables understanding of the structural organization of the MADS domain proteins, including support for predicted helices based on correlated mutation patterns, and evidence for a specific interaction site in those proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979667"}
{"pmid": "20979669", "title": "Living the high life: high-altitude adaptation.", "content": "Living the high life: high-altitude adaptation. Genome-wide scans demonstrate that genetic variants associated with high-altitude adaptation in Tibetans and Andeans arose independently as a result of convergent adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979669"}
{"pmid": "20979670", "title": "Hypercapnic respiratory failure in obesity-hypoventilation syndrome: CO₂ response and acetazolamide treatment effects.", "content": "Hypercapnic respiratory failure in obesity-hypoventilation syndrome: CO₂ response and acetazolamide treatment effects. In obesity-hypoventilation-syndrome patients mechanically ventilated for hypercapnic respiratory failure we investigated the relationship between CO₂ response, body mass index, and plasma bicarbonate concentration, and the effect of acetazolamide on bicarbonate concentration and CO₂ response. CO₂ response tests and arterial blood gas analysis were performed in 25 patients ready for a spontaneous breathing test, and repeated in a subgroup of 8 patients after acetazolamide treatment. CO₂ response test was measured as (1) hypercapnic drive response (the ratio of the change in airway occlusion pressure 0.1 s after the start of inspiratory flow to the change in P(aCO₂)), and (2) hypercapnic ventilatory response (the ratio of the change in minute volume to the change in P(aCO₂)). We did not find a significant relationship between CO₂ response and body mass index. Patients with higher bicarbonate concentration had a more blunted CO₂ response. Grouping the patients according to the first, second, and third tertiles of the bicarbonate concentration, the hypercapnic drive response was 0.32 ± 0.17 cm H₂O/mm Hg, 0.22 ± 0.15 cm H₂O/mm Hg, and 0.10 ± 0.06 cm H₂O/mm Hg, respectively (P = .01), and hypercapnic ventilatory response was 0.46 ± 0.23 L/min/mm Hg, 0.48 ± 0.36 L/min/mm Hg, and 0.22 ± 0.16 L/min/mm Hg, respectively (P = .04). After acetazolamide treatment, bicarbonate concentration was reduced by 8.4 ± 3.0 mmol/L (P = .01), and CO₂ response was shifted to the left, with an increase in hypercapnic drive response, by 0.14 ± 0.16 cm H₂O/mm Hg (P = .02), and hypercapnic ventilatory response, by 0.11 ± 0.22 L/min/mm Hg (P = .33). Patients with obesity-hypoventilation syndrome and higher bicarbonate concentrations had a more blunted CO₂ response. Body mass index was not related to CO₂ response. Acetazolamide decreased bicarbonate concentration and increased CO₂ response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979670"}
{"pmid": "20979671", "title": "Effects of a flutter mucus-clearance device on pulmonary function test results in healthy people 85 years and older in China.", "content": "Effects of a flutter mucus-clearance device on pulmonary function test results in healthy people 85 years and older in China. To investigate the impact of a new flutter-type mucus-clearance device on pulmonary function test results in people ≥ 85 years old. We conducted a randomized controlled trial with 60 people ≥ 85 years old. The subjects were distributed randomly into an intervention group and a control group. Spirometry was performed at baseline and after 28 days of using the flutter mucus-clearance device. We recorded peak expiratory flow (PEF), FEV₁, forced vital capacity (FVC), and FEV₁/FVC. The intervention group used the flutter mucus-clearance device during pulmonary exercises. The control group had no interventions other than routine healthcare. We recorded episodes of fever, antibiotic therapy, and hospital visits during the 28 days of the study. PEF, FEV₁, FVC and FEV₁/FVC showed no significant differences between the 2 groups at baseline. The mean ± SD baseline values were: PEF 103.2 ± 43.0 L/min, FEV₁ 0.98 ± 0.43 L, and FVC 1.76 ± 0.68 L. Compared to baseline, on day 28 there was no significant difference in PEF, FEV₁, or FEV₁/FVC, in either group. The mean ± SD difference in FVC between baseline and day 28 was 0.33 ± 0.30 L in the intervention group, and 0.20 ± 0.14 L in the control group (P = .03). There were no significant differences in the number of cases of fever, antibiotic therapy, or hospital visits between the groups. The new flutter mucus-clearance device improved elderly patients' FVC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979671"}
{"pmid": "20979672", "title": "Quantitative analysis of acid-base disorders in patients with chronic respiratory failure in stable or unstable respiratory condition.", "content": "Quantitative analysis of acid-base disorders in patients with chronic respiratory failure in stable or unstable respiratory condition. The Stewart approach theorizes that plasma pH depends on P(aCO₂), the strong ion difference, and the plasma total concentration of non-volatile weak acids (A(tot)). The conventional approach measures standardized base excess, bicarbonate (HCO₃⁻), and the anion gap. To describe acid-base disorders with the Stewart approach and the conventional approach in patients with chronic respiratory failure. This was an observational prospective study in a medical intensive care unit and a pneumology ward of a university hospital. There were 128 patients included in the study, of which 14 had more than one admission, resulting in 145 admissions. These were allocated to 4 groups: stable respiratory condition and elevated HCO₃⁻ (Group 1, n = 23), stable respiratory condition and non-elevated HCO₃⁻ (Group 2, n = 41), unstable respiratory condition and elevated HCO₃⁻ (Group 3, n = 44), and unstable respiratory condition and non-elevated HCO₃⁻ (Group 4, n = 37). Elevated HCO₃⁻ was defined as ≥ 3 standard deviations higher than the mean value we found in 8 healthy volunteers. Measurements were taken on admission. In groups 1, 2, 3, and 4, the respective mean ± SD values were: HCO₃⁻ 33 ± 3 mM, 26 ± 3 mM, 37 ± 4 mM, and 27 ± 3 mM (P < .001); strong ion difference 45 ± 3 mM, 38 ± 4 mM, 46 ± 4 mM, and 36 ± 4 mM (P < .001); and A(tot) 12 ± 1 mM, 12 ± 1 mM, 10 ± 1 mM, 10 ± 2 mM (P < .001). Non-respiratory disorders related to high strong ion difference were observed in 12% of patients with elevated HCO₃⁻, and in none of those with non-elevated HCO₃⁻ (P = .003). Non-respiratory disorders related to low strong ion difference were observed in 9% of patients with non-elevated HCO₃⁻, and in none of those with elevated HCO₃⁻ (P = .02). Hypoalbuminemia was common, especially in unstable patients (group 3, 66%; group 4, 65%). Normal standardized base excess (16%), HCO₃⁻ (28%), and anion gap (30%) values were common. The Stewart approach detected high effective strong ion difference in 13% of normal standardized base excess, and in 20% of normal anion gap corrected for albuminemia, and low effective strong ion difference in 22% of non-elevated HCO₃⁻. In patients with chronic respiratory failure the acid-base pattern is complex, metabolic alkalosis is present in some patients with elevated HCO₃⁻, and metabolic acidosis is present in some with non-elevated HCO₃⁻. The diagnostic performance of the Stewart approach was better than that of the conventional approach, even when corrected anion gap was taken into account.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979672"}
{"pmid": "20979673", "title": "Agreement between functional residual capacity estimated via automated gas dilution versus via computed tomography in a pleural effusion model.", "content": "Agreement between functional residual capacity estimated via automated gas dilution versus via computed tomography in a pleural effusion model. The measurement of functional residual capacity (FRC) in ventilated patients could help track the extent of acute lung disease, monitor recruitment of unstable lung units, or guide the use of PEEP. Quantitative analysis of computed tomography (CT) images of the lungs is currently the accepted standard for FRC measurement (FRC-CT), but is impractical for routine use. Gas dilution and gas tracer technologies, while attractive for research applications, require specialized equipment and skills missing from the clinical setting. We simultaneously evaluated FRC-CT and FRC determined by a ventilator-incorporated wash-in/wash-out (FRC-WI/WO) method in an animal model of unilateral pleural effusion that varied the fluid volume instilled and the applied PEEP. A swine model (n = 6) of unilateral pleural effusion was created by injecting boluses of radio-opaque fluid (iopromide) (13 mL/kg and then 26 mL/kg) into the right thoracic cavity. FRC-CT and FRC-WI/WO were simultaneously obtained, at 2 PEEP levels, at baseline and at both pleural-effusion volumes. A correlation coefficient (r²) of 0.89 between FRC-CT and FRC-WI/WO revealed concordance between the techniques, with directional agreement and acceptable bias and precision under all tested conditions. We found excellent concordance between FRC-WI/WO and FRC-CT in an animal model of unilateral pleural effusion that stressed the capability of this technology. The technical advantage of the wash-in/wash-out technique is its incorporation into ventilator operation without requiring adjustments to ventilation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979673"}
{"pmid": "20979674", "title": "Radiation dose to patients and clinicians during fluoroscopically-guided biopsy of peripheral pulmonary lesions.", "content": "Radiation dose to patients and clinicians during fluoroscopically-guided biopsy of peripheral pulmonary lesions. Fluoroscopic guidance may be utilized in some bronchoscopic procedures, including ultrasound-guided bronchoscopy for investigation of peripheral pulmonary lesions. Some authors have suggested this procedure may be performed without fluoroscopy, to minimize risks due to radiation exposure. However, the radiation dose has never been quantified, so the risk remains unknown. To determine the patient and clinician radiation exposure from fluoroscopy during bronchoscopy. We recorded exposure parameters during 45 consecutive ultrasound bronchoscopies with fluoroscopic guidance with a mobile C-arm fluoroscopy system. We calculated the patient effective radiation dose with Monte Carlo computer simulations. Passive personal film dosimeters were placed on 4 sites on both the proceduralist and the primary nursing assistant. The mean fluoroscopy screening time was 96 ± 55 s. Patients received a median effective radiation dose of 0.49 ± 0.37 milli-Sieverts (mSv) (range 0.16-1.3 mSv). Only the film dosimeters worn outside the clinicians' protective aprons recorded measurable radiation doses. Based on typical attenuation properties of the protective garments across the diagnostic x-ray energy range, we estimate that the effective radiation dose per procedure to the proceduralist was 0.4 micro-Sieverts (μSv) and to the assistant was 0.2 μSv. Patients are exposed to relatively small amounts of radiation from fluoroscopy during bronchoscopy. Clinically indicated fluoroscopic guidance during bronchoscopy should not be precluded on the basis of radiation safety concerns. Adequate shielding of clinicians results in negligible radiation doses during ultrasound bronchoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979674"}
{"pmid": "20979676", "title": "Goal-directed therapy for severely hypoxic patients with acute respiratory distress syndrome: permissive hypoxemia.", "content": "Goal-directed therapy for severely hypoxic patients with acute respiratory distress syndrome: permissive hypoxemia. Permissive hypoxemia is a lung-protective strategy that aims to provide a patient with severe acute respiratory distress syndrome (ARDS) a level of oxygen delivery that is adequate to avoid tissue hypoxia while minimizing the detrimental effects of the often toxic ventilatory support required to maintain normal arterial oxygenation. However, in many patients with severe ARDS it can be difficult to achieve a balance between maintaining adequate tissue oxygenation and avoiding ventilator-induced lung injury (VILI). A potential strategy for the management of such patients involves goal-oriented manipulation of cardiac output and, if necessary, hemoglobin concentration, to compensate for hypoxemia and maintain a normal (but not supranormal) value of oxygen delivery. Although it has not yet been studied, this approach is theorized to improve clinical outcomes of critically ill patients with severe ARDS. We stress that the goal of this article is not to convince the reader that this approach is necessarily correct, as data are clearly lacking, but rather to provide a basis for continued thought, discussion, and potential research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979676"}
{"pmid": "20979677", "title": "Chemotherapy-associated recurrent pneumothoraces in lymphangioleiomyomatosis.", "content": "Chemotherapy-associated recurrent pneumothoraces in lymphangioleiomyomatosis. Lymphangioleiomyomatosis is a rare cause of pneumothorax in women. We present the case of a 48-year-old woman with lymphangioleiomyomatosis, who had never had a pneumothorax prior to commencing chemotherapy for breast cancer. During chemotherapy she developed 3 pneumothoraces and 2 episodes of pneumomediastinum. We suggest that the pneumothoraces were caused by the chemotherapy. To our knowledge, this is the first reported case of chemotherapy triggering pneumothoraces in a woman with lymphangioleiomyomatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979677"}
{"pmid": "20979678", "title": "Intercostal artery laceration following thoracentesis.", "content": "Intercostal artery laceration following thoracentesis. Intercostal artery laceration is an unusual complication following thoracentesis, and has been reported only in elderly patients. We report a case of a 78-year-old man who developed a massive hemothorax following thoracentesis. Post-thoracentesis radiograph revealed a substantial increase in pleural fluid, and emergency chest tube insertion identified the hemothorax. He underwent right thoracotomy for repair of the intercostal artery laceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979678"}
{"pmid": "20979675", "title": "Tai chi exercise for patients with chronic obstructive pulmonary disease: a pilot study.", "content": "Tai chi exercise for patients with chronic obstructive pulmonary disease: a pilot study. To determine the feasibility of a randomized controlled trial of the effect of a tai chi program on quality of life and exercise capacity in patients with COPD. We randomized 10 patients with moderate to severe COPD to 12 weeks of tai chi plus usual care (n = 5) or usual care alone (n = 5). The tai chi training consisted of a 1-hour class, twice weekly, that emphasized gentle movement, relaxation, meditation, and breathing techniques. Exploratory outcomes included disease-specific symptoms and quality-of-life, exercise capacity, pulmonary function tests, mood, and self-efficacy. We also conducted qualitative interviews to capture patient narratives regarding their experience with tai chi. The patients were willing to be randomized. Among 4 of the 5 patients in the intervention group, adherence to the study protocol was excellent. The cohort's baseline mean ± SD age, percent-of-predicted FEV₁, and ratio of FEV₁ to forced vital capacity were 66 ± 6 y, 50 ± 12%, and 0.63 ± 0.14, respectively. At 12 weeks there was significant improvement in Chronic Respiratory Questionnaire score among the tai chi participants (1.4 ± 1.1), compared to the usual-care group (-0.1 ± 0.4) (P = .03). There were nonsignificant trends toward improvement in 6-min walk distance (55 ± 47 vs -13 ± 64 m, P = .09), Center for Epidemiologic Studies Depression Scale (-9.0 ± 9.1 vs -2.8 ± 4.3, P = .20), and University of California, San Diego Shortness of Breath score (-7.8 ± 3.5 vs -1.2 ± 11, P = .40). There were no significant changes in either group's peak oxygen uptake. A randomized controlled trial of tai chi is feasible in patients with moderate to severe COPD. Tai chi exercise as an adjunct to standard care warrants further investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979675"}
{"pmid": "20979679", "title": "Cryptococcosis in the immunocompetent patient.", "content": "Cryptococcosis in the immunocompetent patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979679"}
{"pmid": "20979680", "title": "Obesity hypoventilation syndrome: bicarbonate concentration and acetazolamide.", "content": "Obesity hypoventilation syndrome: bicarbonate concentration and acetazolamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979680"}
{"pmid": "20979681", "title": "Flutter-type mucus-clearance devices and pulmonary function in the elderly.", "content": "Flutter-type mucus-clearance devices and pulmonary function in the elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979681"}
{"pmid": "20979683", "title": "Randomised trials on vitamin C.", "content": "Randomised trials on vitamin C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979683"}
{"pmid": "20979682", "title": "Amelioration of hyperglycaemia and its associated complications by finger millet ( Eleusine coracana L.) seed coat matter in streptozotocin-induced diabetic rats.", "content": "Amelioration of hyperglycaemia and its associated complications by finger millet ( Eleusine coracana L.) seed coat matter in streptozotocin-induced diabetic rats. Finger millet (Eleusine coracana) is extensively cultivated and consumed in India and Africa. The millet seed coat is a rich source of dietary fibre and phenolic compounds. The effect of feeding a diet containing 20% finger millet seed coat matter (SCM) was examined in streptozotocin-induced diabetic rats. Diabetic rats maintained on the millet SCM diet (diabetic experimental (DE) group) for 6 weeks exhibited a lesser degree of fasting hyperglycaemia and partial reversal of abnormalities in serum albumin, urea and creatinine compared with the diabetic control (DC) group. The DE group of rats excreted comparatively lesser amounts of glucose, protein, urea and creatinine and was accompanied by improved body weights compared with their corresponding controls. Hypercholesterolaemia and hypertriacylglycerolaemia associated with diabetes were also notably reversed in the DE group. Slit lamp examination of the eye lens revealed an immature subcapsular cataract with mild lenticular opacity in the DE group of rats compared to the mature cataract with significant lenticular opacity and corneal vascularisation in the DC group. Lower activity of lens aldose reductase, serum advanced glycation end products and blood glycosylated Hb levels were observed in the DE group. The millet SCM feeding showed pronounced ameliorating effects on kidney pathology as reflected by near normal glomerular and tubular structures and lower glomerular filtration rate compared with the shrunken glomerulus, tubular vacuolations in the DC group. Thus, the present animal study evidenced the hypoglycaemic, hypocholesterolaemic, nephroprotective and anti-cataractogenic properties of finger millet SCM, suggesting its utility as a functional ingredient in diets for diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979682"}
{"pmid": "20979684", "title": "Follicular interactions affect the in vitro development of isolated goat preantral follicles.", "content": "Follicular interactions affect the in vitro development of isolated goat preantral follicles. The aim of this study was to evaluate the influence of the number of follicles per drop (one or three) and antral follicles on in vitro development of isolated goat preantral follicles. Preantral follicles were isolated through microdissection and distributed individually (control) or in groups of three follicles (treatment) in microdroplets of α-MEM with or without 1000 ng/ml follicle stimulating hormone (FSH) for Experiments 1 and 2, respectively. Experiment 3 was divided into four treatments according to the presence of one or three preantral follicles, associated or not with antral follicles. After culture, oocytes were retrieved from morphologically normal follicles and submitted to in vitro maturation (IVM) and live/dead fluorescent labelling. Results of Experiment 1 (basic medium without FSH) showed that culture of preantral follicles in groups enhances viability, growth and antrum formation after 12 days. However, in the presence of FSH (Experiment 2), only the recovery rate of fully grown oocytes for IVM was significantly affected by grouping of follicles. In Experiment 3, in general, co-culture of preantral follicles with an early antral follicle had a detrimental effect on viability, antrum formation and production of oocytes for IVM. In conclusion, the performance of in vitro culture of goat preantral follicles is affected by the number of follicles per drop, the presence of an antral follicle and FSH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979684"}
{"pmid": "20979685", "title": "Early presentation of endomyocardial fibrosis in a 22-month-old child: a case report.", "content": "Early presentation of endomyocardial fibrosis in a 22-month-old child: a case report. We present an unusual, biopsy-proven case of endomyocardial fibrosis in a 22-month-old male child, which progressed rapidly resulting in death. The patient was born to a father originating from Mozambique, where the disease is endemic but who had not himself travelled there, suggesting a genetic link. Other remarkable features were the presence of a right ventricular diverticulum, and a positive Mycoplasma pneumoniae immunoglobulin M enzyme-linked immunosorbent assay test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979685"}
{"pmid": "20979686", "title": "Getting out what we put in: productivity of the English National Health Service.", "content": "Getting out what we put in: productivity of the English National Health Service. Many countries are incorporating direct measures of non-market outputs in the national accounts. For any particular output to be included there has to be data about it for two adjacent periods. This is problematic because the classification of non-market outputs is often subject to wholesale revision. We outline the challenges associated with classification changes and propose a solution. To illustrate we construct output and input indices and estimate productivity growth of the English National Health Service (NHS) for the period 2003-2004 to 2007-2008. Our index of output growth incorporates all care provided to NHS patients and captures improvements in survival rates, waiting times and disease management. We find that more patients are being treated and the quality of the care they receive has been improving. We implement our approach to dealing with changes as to how health services are defined and show what effect this has on estimates of output growth. Our index of input growth captures all labour, intermediate and capital inputs into health service production and we improve on how capital has been measured in the past. Inputs have increased over time but there has also been a slowdown since 2005-2006, primarily the result of a levelling off in staff recruitment and less reliance on the use of agency staff. Productivity is assessed by comparing output growth with growth in inputs, the net effect being constant productivity growth between 2003-2004 and 2007-2008.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979686"}
{"pmid": "20979687", "title": "PEGylated guanidinylated polyallylamine as gene-delivery carrier.", "content": "PEGylated guanidinylated polyallylamine as gene-delivery carrier. A novel cationic co-polymer was developed by grafting poly(ethylene glycol) (PEG) on guanidinylated polyallylamine (PAA) for gene delivery. Characterization of PEG-g-guanidinylated PAA/DNA complexes demonstrated that particle size increased and surface charge decreased with increasing the amount of PEG. The results of cytotoxicity assay proved that grafted PEG could effectively decrease the cytotoxicity of the complexes. In transfection efficiency assay, HeLa cells treated with PEG(2)-g-guanidinylated PAA (formed with 17.5 μmol guanidinylated PAA and 2 μmol PEG)/DNA (0.2 μg EGFP plasmid) complexes showed a very high level of EGFP expression. In conclusion, combination of guanidinylation and PEGylation could effectively decrease the cytotoxicity and significantly increase the transfection efficiency of PAA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979687"}
{"pmid": "20979690", "title": "Using CT imaging to delineate the prostatic apex for radiation treatment planning.", "content": "Using CT imaging to delineate the prostatic apex for radiation treatment planning. In computed tomography (CT)-based radiotherapy planning for prostate cancer, it is difficult to precisely delineate the prostatic apex because of its relationship with the urogenital diaphragm and bulbospongiosus musculature. In this retrospective study, we analyzed the magnetic resonance imaging (MRI) and CT scans of the patients with prostate cancer to investigate the relationship between the prostatic apex and the anatomic structure visible on CT, and to provide evidence for localizing the prostatic apex in radiotherapy planning. MRI and CT scans of 108 patients with prostate cancer were analyzed to measure the distances between the prostatic apex and the bottom of ischial tuberosities, the bottom of obturator foramen, the bottom of pubic symphysis, and the bulb of the penis. The volume of the prostate was measured to analyze its relationship with the localization of the prostatic apex. The prostatic apex was located (13.1±3.3) mm above the bulb of the penis, (11.0±5.4) mm above the bottom of the obturator foramen, (31.3±5.5) mm above the ischial tuberosities, and (7.1±4.7) mm above the bottom of the symphysis pubis. There was no correlation between the size of the prostate and the localization of the prostatic apex. The variance of the distance between the prostatic apex and the bulb of the penis is smaller than that of the distance between the apex and bony anatomy. Delineating the target to 6 mm above the bulb of the penis can cover the prostatic apex in 95% of the patients with prostate cancer, delineating to the bottom of obturator foramen can cover the prostatic apex in 100% of the patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979690"}
{"pmid": "20979688", "title": "Structure and biocompatibility of an injectable bone regeneration composite.", "content": "Structure and biocompatibility of an injectable bone regeneration composite. With the development of minimally invasive techniques, injectable materials have become one of the major hotspots in the biomaterial field. We have developed an injectable bone regeneration composite (IBRC) using calcium alginate hydrogel as matrix to carry nano-hydroxyapatite/collagen particles. In this work, we evaluated the homogeneity of IBRC by dry/wet weight ratio test. The results showed that the structural homogeneity was determined by controlling the molar ratios of trisodium phosphate to calcium sulfate rather than alginate concentration in the studied ranges. Pore sizes of wet IBRC samples were characterized by thermoporometry. The pore properties of dried IBRC were tested by mercury porosimetry. Average pore size and porosity of dried IBRC declined with increasing alginate concentration. In contrast, surprisingly, pore size of wet homogeneous IBRC increased with increasing alginate concentration. Meanwhile, the swelling ratio did not increase with varying alginate concentration, but the swelling degree increased with increasing alginate concentration. In vitro cell culture showed that IBRC had no obvious cytotoxic effect on the rat bone mesenchymal stem cells. The morphology and viability of cells were also related to MR value. IBRC had good histocompatibility with a mild short-term inflammatory response in rat dorsum muscle. In addition, the excellent ability of IBRC to promote bone healing was confirmed by 5-mm-diameter cranial defects using histological analysis and bone mineral density measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979688"}
{"pmid": "20979689", "title": "Adjuvant interferon therapy for malignant melanoma: the debate.", "content": "Adjuvant interferon therapy for malignant melanoma: the debate. Based on the results of the Kirkwood high-dose interferon alpha-2b (HDI) adjuvant therapy trial of the Eastern Cooperative Oncology Group 1684, the US Food and Drug Administration (FDA) approved HDI as the postoperative adjuvant therapy for high-risk melanoma. Unfortunately, controversies continue regarding the use of interferon (IFN) as adjuvant therapy for melanoma owing to the inconsistent results of subsequent trials. Numerous trials of adjuvant interferon therapy demonstrated a benefit in terms of relapse-free survival (RFS), but without confirmed significant effect on overall survival (OS). The optimal timing, dose, and type of interferon are not yet defined. Therefore, adjuvant interferon treatment is preferentially applied in the randomized clinical trials in specialized centers. Decisions about the appropriateness of adjuvant interferon alfa-2b treatment for patients should be made on an individual basis, after discussion with the patient, including an explanation of the potential benefits and side effects of interferon therapy. Moreover, we also need to use available regimens reasonably, seek feasible and predictable prognostic factors to serve patients with individualized therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979689"}
{"pmid": "20979691", "title": "Prognosis of 980 patients with gastric cancer after surgical resection.", "content": "Prognosis of 980 patients with gastric cancer after surgical resection. Although surgery is the only possible means to cure gastric cancer, the prognosis is often discrepant. The American Joint Committee on Cancer / International Union against Cancer (AJCC/UICC) published the TNM classification of Malignant Tumors (seventh edition) for gastric cancer recently. This study aimed to use this new edition staging system to investigate the prognostic factors for gastric cancer. The clinicopathologic data of 980 patients with gastric cancer treated by surgical resection in our hospital between January 2000 and December 2006 were analyzed retrospectively. The overall survival rate was determined by using Kaplan-Meier method and log-rank test was used to determine significance. The prognosis was analyzed using univariate analysis and multivariate analysis with the Cox proportional hazards model. The 6th and 7th edition AJCC/UICC TNM staging systems were used to compare the survival outcomes for the cohort of patients. The overall 1-, 3-, 5-year survival rates for the whole group were 82.5%, 58.7%, and 52.6%. The 5-year survival rates for patients with pTNM stage I, II, III, and IV disease classified by the 7th edition staging system were 93.2%, 72.4%, 39.1%, and 5.2%, respectively. In both univariate analysis and Cox multivariate analysis, age, tumor site, tumor size, histological type, resection type, radical resection, lymphatic/venous invasion, depth of invasion, nodal status, metastasis, retrieved lymph nodes, metastatic lymph node ratio, and adjuvant chemotherapy were prognostic factors with these patients. Compared with the 6th edition system, the new edition of TNM staging system for gastric cancer can accurately predict the survival after operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979691"}
{"pmid": "20979693", "title": "Relationship between traditional Chinese medicine syndrome differentiation and imaging characterization to the radiosensitivity of nasopharyngeal carcinoma.", "content": "Relationship between traditional Chinese medicine syndrome differentiation and imaging characterization to the radiosensitivity of nasopharyngeal carcinoma. Traditional Chinese medicine (TCM) is a well established and time-honored practice in China, employing syndrome differentiation as a basis for the treatment of disease. According to different TCM syndrome typing findings, combining modern medical methods with TCM approaches can improve the quality of life and comprehensive effect on patients with nasopharyngeal carcinoma (NPC). This study investigated the relationship between TCM syndrome typing and imaging characterization to radiosensitivity as to provide objective evidence for the integration of Chinese and modern medical approaches in the treatment of NPC. Prior to treatment, TCM syndrome typing, computed tomography (CT) and magnetic resonance imaging (MRI) were performed on 147 patients pathologically classified with NPC. The status of tumor remission was radiologically evaluated at accumulated doses of 20 Gy, 40 Gy and 60 Gy, and at 3 months after completion of radiotherapy. Statistical results were analyzed by the Friedman and K-W test procedures. Prior to treatment, TCM syndrome typing of NPC included Lung Heat, Blood Stasis, Phlegm Congealment and Blood Stasis-Phlegm Congealment. Lung Heat typing accounted for the highest proportion at 34.7% (51/147), followed by Phlegm Congealment at 32.7% (48/147), Blood Stasis at 17.0% (25/147) and Blood Stasis-Phlegm Congealment at 15.7% (23/147). Radiological imaging demonstrated a higher incidence of cervical lymph node metastases in Phlegm Congealment and Blood Stasis-Phlegm Congealment types (P<0.05), while Blood Stasis and Blood Stasis-Phlegm Congealment types were more prone to skull base invasion (P<0.05). Residual tumor size was larger in Blood Stasis and Blood Stasis-Phlegm Congealment types than in Lung Heat and Phlegm Congealment types after 3 months of treatment (P<0.05). Different radiological manifestations were observed in TCM syndrome typed NPC patients, with lesser radiosensitivity demonstrated in the Blood Stasis and the Blood Stasis-Phlegm Congealment types relative to the Lung Heat and Phlegm Congealment types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979693"}
{"pmid": "20979692", "title": "Expression of BC047440 protein in hepatocellular carcinoma and its relationship to prognosis.", "content": "Expression of BC047440 protein in hepatocellular carcinoma and its relationship to prognosis. BC047440 is a new gene related to cancer growth and proliferation. Due to the lack of specific antibodies, how BC047440 protein influences the liver cancer growth is unclear. This study aimed to determine the relationship between BC047440 protein expression and clinicopathologic parameters of hepatocellular carcinoma (HCC), and to evaluate the prognostic value of BC047440 for HCC patients. We prepared the polyclonal antibodies of BC047440, and used Western blot and immunohistochemical staining to detect BC047440 expression in 68 specimens of HCC. The correlations of BC047440 expression to clinicopathologic features and prognosis of HCC patients were analyzed. The polyclonal antibodies could effectively recognize endogenous BC047440 in HCC tissues. The positive rate of BC047440 protein was significantly higher in HCCs than in adjacent tissues (44.1% vs. 23.5%, P<0.05); the rate was significantly higher in patients with larger tumor (P<0.05) and portal vein invasion (P<0.01). The HCC patients with high BC047440 expression showed a significantly poorer prognosis than those with low BC047440 expression (P<0.05). BC047440 can promote the growth and invasion of HCC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979692"}
{"pmid": "20979694", "title": "Risk factors for acute kidney injury in patients undergoing allogeneic hematopoietic stem cell transplantation.", "content": "Risk factors for acute kidney injury in patients undergoing allogeneic hematopoietic stem cell transplantation. Allogeneic hematopoietic cell transplantation (allo-HSCT) is a potent procedure for the treatment of hematologic diseases, yet it is associated with high risks of treatment-related complications. Except for transplant-related organ toxicities, renal insufficiencies which emerge earlier significantly limit patients' long survival. To analyze risk factors for acute kidney injury (AKI), we conducted a retrospective cohort study of 96 patients undergoing HSCT. During the first 100 days after allo-HSCT, all patients were evaluated for renal function by measuring serum creatinine clearance and glomerular filtration rate (GFR) with a classification below: Grade 0 (<25%, decline in creatinine clearance), Grade 1 (≥25% decline in creatinine clearance but <2-fold increase in serum creatinine), Grade 2 (≥2-fold rise in serum creatinine but no need for dialysis), and Grade 3 (≥2-fold rise in serum creatinine and need for dialysis). Cox regression model was used to calculate the hazard ratios (HRs) of demographic data, clinical variables, and risk factors for AKI. Twenty-eight (29.2%) patients occurred Grades 1-3 renal dysfunction (Grade 1, 14 patients; Grade 2, 12 patients; Grade 3, 2 patients), and ratios of early kidney injury increased in high-risk malignancy group (HR = 2.945, 95% confidence interval (CI)=1.293-6.421), patients treated with myeloablative conditioning regimen (HR=2.463, 95% CI=1.757-4.320), and patients with acute GVHD (HR=3.553, 95% CI=1.809-6.978), sepsis (HR=3.215, 95% CI=1.189-6.333 ), or hepatic veno-occlusive disease (VOD) (HR=3.487, 95% CI=1.392-6.524). Whereas, HLA histocompatibility showed no striking increased risk for acute renal injury (HR=1.684, 95% CI=0.648-4.378). The survival rate was lower in patients with severe nephrotoxicity (21.4%) than in patients without nephrotoxicity (70.6%) (P=0.001). Nephrotoxicity is the primary risk factor for AKI, severely impacting on survival. Sorts of risk factors mentioned will be useful for evaluation for kidney function of patients undergoing allo-HSCT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979694"}
{"pmid": "20979696", "title": "Efficacy of concurrent chemoradiotherapy plus adjuvant chemotherapy on advanced cervical cancer.", "content": "Efficacy of concurrent chemoradiotherapy plus adjuvant chemotherapy on advanced cervical cancer. Concurrent chemoradiotherapy for cervical carcinoma develops rapidly and has become a common and standard therapy in recent years. Both the local control rate and survival rate of patients were increased and the risk of death fell by 30%-50%. This study aimed to explore the efficacy of concurrent chemoradiotherapy plus adjuvant chemotherapy on and the treatment compliance of the patients with advanced cervical squamous cell carcinoma. A total of 156 patients with stage IIa-IIIb cervical squamous cell carcinoma were randomly divided into the concurrent chemoradiotherapy group (experimental group) and radiotherapy group (control group). Intracavity and external beam radiation therapy were administered. At point A, 40-48 Gy were given by 10-12 fractions; at point B, 46-50 Gy were given by 23-25 fractions. In the same time, experimental group was treated by cisplatin (DDP, 40 mg) on day 1, repeated every week. Ten days after radiation therapy, TP regimen was administered as adjuvant chemotherapy. For the experimental and control groups, the objective response rates were 88.61% and 75.32%, 1-year survival rates were 88.57% and 70.77%, 1-year local control rates were 81.43% and 64.62%, 3-year survival rates were 82.14% and 57.69%, and 3-year local control rates were 75.00% and 46.15%, with significant differences (P<0.05). Quality of life of all patients were significantly improved after treatment (P<0.05). Concurrent chemoradiotherapy plus adjuvant chemotherapy for advanced cervical cancer can improve short-term and long-term survival and local control rates of patients, improve the quality of life, and the toxicity can be tolerated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979696"}
{"pmid": "20979695", "title": "The recruitment of exogenous endothelial progenitor cells in lung tumor model of nude mice.", "content": "The recruitment of exogenous endothelial progenitor cells in lung tumor model of nude mice. Endothelial progenitor cells (EPCs) play an important role in hypoxia-triggered tumor vasculogenesis. However, the homing of exogenous EPCs in tumors is still unclear. In this study, we investigated the recruitment of exogenous EPCs in human lung adenocarcinoma model of nude mice. EPCs labeled with green fluorescence protein (GFP) were transplanted into nude mice bearing human lung adenocarcinoma. The growth of tumor was observed. After the mice were killed, GFP-EPCs in different tissues were examined by fluorescence. The tumor tissues were stained for CD133, hypoxia-inducible factor-1alpha (HIF-1α), stromal cell-derived factor-1α (SDF-1α), and vascular endothelial growth factor receptor (KDR). Real-time polymerase chain reaction of CD133, HIF-1α, SDF-1α, and VEGF-1 were also performed. The growth of tumor in EPC group was significantly faster than that in saline solution group (P <0.05). Under fluorescence microscope, GFP-EPCs were strongly expressed in both tumor and bone marrow. EPCs were recruited to the tumor periphery to participate in tumor vasculogenesis. The expression of CD133, HIF-1α, and SDF-1 mRNA in tumor and bone marrow were significantly higher than that in the liver, spleen, and skin (P<0.05). Exogenous EPCs can be recruited to tumor and accelerate tumor growth. Except tumor, bone marrow can also recruit EPCs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979695"}
{"pmid": "20979697", "title": "Primary malignant bone neoplasm: a case report of dedifferentiated chondrosarcoma in the rib and review of the literature.", "content": "Primary malignant bone neoplasm: a case report of dedifferentiated chondrosarcoma in the rib and review of the literature. Dedifferentiated chondrosarcoma (DDCS) is a rare but highly malignant primary bone neoplasm, which is resistant to radiotherapy and chemotherapy. There remains uncertainly as to the best treatment of this disease and how to improve its prognosis. In this paper we reported a case of DDCS and reviewed the related literatures in order to provide references to throw a light on the histogenesis, diagnosis and therapy of this disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979697"}
{"pmid": "20979698", "title": "Anti-cancer effects of Phyllanthus urinaria and relevant mechanisms.", "content": "Anti-cancer effects of Phyllanthus urinaria and relevant mechanisms. Phyllanthus urinaria (P. urinaria), a widely used herbal medicine, has been reported to possess various biological activities. This report aimed to characterize the whole P. urinaria plant, present the anticancer effects of P. urinaria both in vivo and in vitro, and explore relevant mechanisms. The water extract of P. urinaria not only significantly reduces the cell viability of various cancer cell lines from different origins but also suppresses tumor development in C57BL/6J mice after implantation of Lewis lung carcinoma (LCC) cells. The anticancer activity of P. urinaria extract is mainly due to induced apoptosis of cancer cells as demonstrated by DNA fragmentation and increased caspase-3 activity through both intrinsic and extrinsic pathways. The decrease in viability with P. urinaria treatment might be partially associated with down-regulation of telomerase activation and induction of the apoptotic process. In addition, P. urinaria also exhibits anti-angiogenic activity that is mediated, at least in part, by suppression of matrix metalloproteinase 2 (MMP-2) secretion and inhibition of MMP-2 activity through zinc chelation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979698"}
{"pmid": "20979699", "title": "Current status of surgical treatment for hemorrhoids--systematic review and meta-analysis.", "content": "Current status of surgical treatment for hemorrhoids--systematic review and meta-analysis. Hemorrhoids are one of the most common anorectal disorders. Conventional hemorrhoidectomy is the most commonly practiced surgical technique. Stapled hemorrhoidectomy (procedure for prolapse and hemorrhoids [PPH]) and Ligasure hemorrhoidectomy are newly developed methods for the surgical management of hemorrhoids. The objective of this study was to compare the effectiveness and safety of these two novel techniques with that of conventional hemorrhoidectomy. From the MEDLINE data-base, we obtained papers published between January 2000 and September 2009 and retrospectively studied randomized, controlled clinical trials that compared PPH versus conventional hemorrhoidectomy or Ligasure hemorrhoidectomy versus conventional hemorrhoidectomy. Both PPH and Ligasure hemorrhoidectomy were superior to conventional hemorrhoidectomy with regard to operation time, early postoperative pain, urinary retention, and time to return to normal activity. However, skin tags and recurrent prolapse occurred at higher rates in the PPH group. Although both new techniques have short-term benefits, especially in reducing extreme postoperative pain, more powerful clinical studies with long-term follow up and larger sample sizes should be conducted for further evaluation of outcomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979699"}
{"pmid": "20979700", "title": "Down-regulation of insulin-like growth factor I (IGF-I) in the mouse diaphragm during sepsis.", "content": "Down-regulation of insulin-like growth factor I (IGF-I) in the mouse diaphragm during sepsis. Diaphragmatic muscle impairment is an important cause of respiratory failure during sepsis. Insulin-like growth factor I (IGF-I) is an anabolic growth factor which prevents muscle degradation and wasting during sepsis, but its role in the diaphragmatic muscle during sepsis is unknown. The aim of this study was to investigate the expression of IGF-I in the diaphragmatic muscle in a murine model of sepsis induced by lipopolysaccharide (LPS). Male B57 mice were peritoneally injected with LPS, and were killed and studied at different time-points, 24 h, 48 h, 72 h, and 96 h after injection. Diaphragm sarcolemmal damage was visualized by orange tracer dye infusion, and the expression of IGF-I, interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in diaphragm tissue extracts were measured using ELISA. LPS induced sarcolemmal damage in diaphragm myofibers from 24 h to 96 h, which was accompanied by a significant increase in IL-1β expression in the tissues while IGF-I levels were down-regulated. No change in TNF-α was observed. Body weights of animals were also reduced, especially at 96 h. The expression of IGF-I in diaphragm tissues was down-regulated during sepsis- induced diaphragm myofiber damage, suggesting that IGF-I may be an important factor in the regulation of diaphragm myofiber repair. Further studies are needed to examine the mechanisms involved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979700"}
{"pmid": "20979701", "title": "The use of simvastatin with aromasin in an ovariectomized rat model: effects on the skeletal system.", "content": "The use of simvastatin with aromasin in an ovariectomized rat model: effects on the skeletal system. Many studies have reported the positive effect on bones of statins that inhibit the action of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and suppress hepatic cholesterol biosynthesis. Recent data suggest that statins used in the treatment of hypercholesterolemia decrease fracture risk and increase bone mineral density (BMD). Aromasin (an aromatase inhibitor) is an effective and well-tolerated drug used in endocrine therapy for the treatment of hormone-sensitive early breast cancer in postmenopausal patients. It has a catabolic effect on the skeletal system and can therefore significantly increase the incidence of fractures. Our study aims to determine the effects of Aromasin and simvastatin plus Aromasin on the BMD in an ovariectomized rat model. In total, 27 female Sprague Dawley rats were subjected to a bilateral oophorectomy. One month after the oophorectomy, the rats were divided into the following 3 groups: (1) The control group, in which water was administered; (2) the Aromasin group in which Aromasin was administered orally; and (3) the Aromasin plus simvastatin group in which a combination of Aromasin and simvastatin was administered orally. The BMD of the lumbar spine (L1-L5) and left femoral bone was measured using dual-energy X-ray absorptiometry (DXA) 1 month after the ovariectomy and 3 months after treatment began. Blood was drawn at the time of oophorectomy and 3 months after treatment began to check the levels of calcium, phosphorus, and alkaline phosphatase (alk-ptase). In the Aromasin plus simvastatin group, the BMD of both the lumbar spine (p=0.003) and the left femoral bone (p=0.001) increased significantly after 3 months of treatment. In comparison with the Aromasin group, the Aromasin plus simvastatin group showed a significant increase in the BMD of both the lumbar spine and the left femoral bone (p=0.04 and p=0.005 respectively). In the Aromasin group, the BMD of the left femoral bone (p=0.01) and that of the lumbar spine both decreased significantly (p=0.001). The calcium, phosphorus, and alk-ptase levels were not significantly different among the 3 groups. In the Aromasin group, catabolic effects on the skeletal system were observed. In the Aromasin plus simvastatin group, the BMD significantly increased. Thus statins may have therapeutic application in the treatment of osteoporosis using Aromasin since they can counterbalance the adverse effects of this drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979701"}
{"pmid": "20979702", "title": "Comparison of airway hyperreactivity in chronic obstructive pulmonary disease and asthma.", "content": "Comparison of airway hyperreactivity in chronic obstructive pulmonary disease and asthma. Airway hyperreactivity (AHR) has been described in patients with chronic obstructive pulmonary disease (COPD). However, the nature and characteristics of AHR in this disease have not been fully investigated. AHR was examined in a sample of 33 patients with COPD and 25 with asthma and compared during continuous inhalation of stepwise increased concentrations of methacholine. Respiratory resistance (Rrs) was measured by the forced oscillation technique and the dose-response curves were recorded. The mean values for both forced vital capacity (FVC) and forced expiratory volume in 1s (FEV1) were well-preserved in subjects with asthma. In contrast, there was an obstructive ventilatory defect in patients with COPD, as evidenced by the FEV1/FVC ratio, which fell below 70%. Upon methacholine challenge, only 54.5% (18/33) of the patients with COPD had AHR, compared with 100% (25/25) of those with asthma. Analysis of the dose-response curves revealed that the patients with COPD had a significantly higher baseline Rrs, and thus lower baseline respiratory conductance (Grs), than those with asthma. The cumulative dose of methacholine capable of provoking a positive reaction was significantly higher in patients with COPD. The slope of the Grs was also less steep in responders with COPD. There was good correlation between the severity of AHR and the initial level of airway narrowing in patients with COPD (r=0.623, p<0.01), but not in those with asthma. AHR is not uncommon in COPD, and it has different characteristics from that occurring in asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979702"}
{"pmid": "20979710", "title": "A case of phlebosclerotic colitis with involvement of the entire colon.", "content": "A case of phlebosclerotic colitis with involvement of the entire colon. Phlebosclerotic colitis is a rare type of ischemic colitis caused by obstruction of the veins in the intestinal wall and adjacent mesentery, and is most commonly seen in the ascending colon. We report a 56-year-old woman presenting with intermittent abdominal pain and diarrhea for three years. She had a liver abscess and two episodes of pancreatitis during this time and experienced progressive body weight loss. Initial radiologic findings showed multiple tortuous threadlike calcifications in the region of the right side of the colon and transverse colon on plain abdominal radiographs and computed tomography images. A colonoscopy demonstrated brownish-black pigmentation on the right side of the colon with scattered hyperemic patches. The more distal along the colon, the more normal the color of the bowel appeared. Follow-up studies revealed calcifications not only alongside the colonic and mesenteric veins, but also extending into the superior and inferior mesenteric veins. These findings have not been reported previously. As noted in our patient, this disease entity may not be confined to the tributaries of the superior mesenteric vein. The entire colon may be involved in advanced disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979710"}
{"pmid": "20979704", "title": "Characteristics of Klebsiella pneumoniae bacteremia in community-acquired and nosocomial infections in diabetic patients.", "content": "Characteristics of Klebsiella pneumoniae bacteremia in community-acquired and nosocomial infections in diabetic patients. Although diabetes mellitus is known as a major risk factor for Klebsiella pneumoniae infection, the differences in clinical characteristics between community-acquired and nosocomial K. pneumoniae bacteremia in diabetic patients have been rarely reported. This retrospective analysis enrolled 193 adult diabetic patients with K. pneumoniae bacteremia hospitalized between January 2005 and December 2006. The chi-squared test, analysis of variance (ANOVA), Student's t test, Fisher exact test, and Cox regression model were used for statistical analysis. Of the enrolled patients, 147 had community-acquired infections and 46 had nosocomial infections. Compared with the community group, the nosocomial group had higher rates of in-hospital mortality (41.3% vs. 18.4%, p=0.001), malignancy (50.0% vs. 19.0%, p<0.001), and leukopenia (21.7% vs. 5.4%, p=0.001) but had lower levels of serum C-reactive protein (124.3 mg/L vs. 188.7 mg/L, p=0.018) and HbA1c (8.1% vs. 9.5%, p=0.025). The rate of infection with the extended-spectrum β-lactamase-producing strain (ESBL infection) in the nosocomial group was 11 times higher than that in the community group (45.7% vs. 4.1%, p<0.001). ESBL infection accounted for 53% of mortality in the nosocomial group. Pneumonia was more common in the nosocomial group, while local abscess was more common in the community group. The risk factors for mortality were pneumonia, leukopenia, cirrhosis, and a high serum creatinine ratio (creatinine level at admission/baseline). The nosocomial group had more ESBL infections which might account for the higher mortality. The HbA1c level during the course of infection did not affect the outcome. Pneumonia, leukopenia, cirrhosis, and a high serum creatinine ratio at admission were the risk factors for poor outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979704"}
{"pmid": "20979706", "title": "Misdiagnosed acute appendicitis in children in the emergency department.", "content": "Misdiagnosed acute appendicitis in children in the emergency department. To identify clinical features that distinguish children with appendicitis who visited the emergency department twice or more from those diagnosed on the first visit to the emergency department. A retrospective review of all children with appendicitis diagnosed in the emergency department between January and December 2004 was conducted. Records were reviewed for all patients on their initial presentation to the emergency department. Clinical features were compared between those children who were misdiagnosed and those who were diagnosed correctly. One hundred seventy-three cases were included (mean age, 10.4 years). Twenty-six (15%) were seen twice or more in the emergency department before appendicitis was diagnosed. Misdiagnosed patients had a relatively shorter duration of symptoms at their initial visit, and most presented late at night. Eighteen misdiagnosed patients (69.2%) initially visited the emergency department within 24 hours of onset of symptoms. Compared with patients diagnosed correctly on initial presentation, misdiagnosed patients had a significantly shorter hospital stay, fewer laboratory tests, and fewer physical findings of right lower quadrant tenderness, muscle guarding, rebound tenderness, fever, and migrating pain. Patients diagnosed late at night had a significantly shorter hospital stay and fewer abdominal ultrasound evaluations. On final presentation, initially misdiagnosed patients had a higher rate of appendiceal perforation than did correctly diagnosed patients. Misdiagnosed appendicitis is a problem in the emergency department. A shorter stay in the emergency department, fewer laboratory tests, less diagnostic imaging, and fewer physical findings may be responsible for misdiagnosed appendicitis late at night in the emergency department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979706"}
{"pmid": "20979703", "title": "Relationships between developmental profiles and ambulatory ability in A follow-up study of preschool children with spastic quadriplegic cerebral palsy.", "content": "Relationships between developmental profiles and ambulatory ability in A follow-up study of preschool children with spastic quadriplegic cerebral palsy. To investigate the follow-up course of developmental profiles in preschool children with spastic quadriplegic (SQ) cerebral palsy (CP) who had varying ambulatory abilities. Forty-eight children with SQ CP between 1 and 5 years old were classified into 2 groups, the ambulatory and non-ambulatory groups, based on Gross Motor Function Classification System (GMFCS) levels during the initial assessment. The developmental profiles, consisting of development quotients (DQs) of 8 domains, were evaluated during the initial assessment and the final assessment one year later. The DQ change index (%) was calculated as 100% X (final DQ-initial DQ)/initial DQ. The DQs of all developmental domains in the non-ambulatory group were lower than those in the ambulatory group on both initial and final assessments (p<0.01). As indicated by the DQ change indices, most DQs in the ambulatory group decreased slightly, whereas those in the non-ambulatory group decreased considerably (p<0.05). Furthermore, fine motor function increased proportionally with age in the ambulatory group, but not in the non-ambulatory group. The DQs of the developmental profiles varied in preschool CP children with different ambulatory abilities. The course of developmental profiles in preschool children with SQ CP evolves with age and relates to the degree of ambulatory function. Knowledge of these developmental profiles may be helpful in understanding, predicting, and managing the developmental problems of these children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979703"}
{"pmid": "20979705", "title": "The electromyographic responses of paraspinal muscles during isokinetic exercise in adolescents with idiopathic scoliosis with a Cobb's angle less than fifty degrees.", "content": "The electromyographic responses of paraspinal muscles during isokinetic exercise in adolescents with idiopathic scoliosis with a Cobb's angle less than fifty degrees. Analysis of electromyographic (EMG) activities in the back during dynamic exercise is needed because more complex loading on the spine is created in comparison with that during static exercise. The purpose of this study is to investigate the difference in bilateral midback and low-back paraspinal muscle (PSM) activities during performance of different resistance isokinetic exercises in healthy subjects and those with scoliosis. Forty-one healthy subjects and thirty-three subjects with adolescent idiopathic scoliosis (AIS) were enrolled. An isokinetic back system in combination with quantitative surface EMG was used to evaluate the dominant and nondominant PSM activities by analyzing the root mean square (RMS) during isokinetic extension and flexion exercise at velocities of 30 degree/s and 90 degree/s. Significantly higher RMS of EMG were found in the dominant medial and lateral PSM of the lumbar region than the non-dominant muscles in the healthy control group and in those with AIS with smaller curves (<20 degrees) during isokinetic flexion and extension exercises. In AIS patients with larger curves (20 to 50 degrees), shifting of muscle activities from the dominant to the non-dominant side occurred during isokinetic exercises, and the EMG activities of the thoracic muscle were significantly higher on the non-dominant (concave) side than on the dominant (convex) side. The bilateral PSM do not act symmetrically during isokinetic back exercises. The dominant lumbar PSM supply the major action in healthy subjects and patients with small curve scoliosis. For larger curve scoliosis, compensated muscle activity is needed in the midback when doing resistance exercises. More midback protection may be needed by scoliotic subjects with large curves during resistance exercise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979705"}
{"pmid": "20979709", "title": "Severe neuroleptic malignant syndrome: successful treatment with high-dose lorazepam and diazepam: a case report.", "content": "Severe neuroleptic malignant syndrome: successful treatment with high-dose lorazepam and diazepam: a case report. Neuroleptic malignant syndrome (NMS) is an idiosyncratic and potentially fatal adverse complication of antipsychotic medications and other dopamine-modulating agents. It is characterized by hyperthermia, muscle rigidity, autonomic dysfunction and alteration in mental status. Here, we report a patient with severe NMS who was successfully treated with highdose lorazepam and diazepam. A 61-year-old man with bipolar I disorder was admitted to the hospital because of manic episodes. Fever, muscle rigidity, tachycardia, diaphoresis, elevated blood pressure and delirium occurred following intramuscular injection of haloperidol and NMS was diagnosed. Supportive treatment included hydration, alkalinized fluids and correction of abnormal electrolytes without the use of dantrolene, dopaminergic agents or electroconvulsive therapy. The Francis-Yacoub NMS rating scale was employed for evaluation of clinical improvement, and scores were 55 on the first day and 0 at discharge. The patient was followed up for 6 months and was free of NMS. In conclusion, this is the first report of rapid relief of NMS with high-dose lorazepam and diazepam in a Taiwanese patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979709"}
{"pmid": "20979707", "title": "Survival impact of initial surgical approach in stage I ovarian cancer.", "content": "Survival impact of initial surgical approach in stage I ovarian cancer. The aim of this study was to evaluate the impact on survival of initial laparoscopic surgery compared with conventional laparotomy in stage I epithelial ovarian cancer. We conducted a retrospective study which enrolled all consecutive patients with stage I epithelial ovarian cancer between January 1984 and December 2006. Patients with a histological diagnosis of epithelial ovarian cancer who underwent laparoscopy were recruited if their cases were compatible with stage I (clinical or surgical) at initial exploration. The independent samples t test, chi-square test, log-rank and Cox proportional hazards model were performed. A total of 208 patients were enrolled, including 34 patients with initial laparoscopy and 174 with laparotomy. The median follow-up time for survivors was 65 (range, 2-276) months. The 5-year overall survival (OS) and recurrence-free survival (RFS) rates were 67.4% and 69.5% in the laparoscopy group, and 88.7% and 78.7% in the laparotomy group, respectively. The median time to recurrence was 14.5 (range, 2-67) months. In multivariate analysis, the initial laparoscopy approach posted significant adverse impacts on the OS (laparoscopy vs laparotomy, the hazard ratio [HR]: 3.52, p=0.009) and the RFS (laparoscopy vs laparotomy, HR: 2.58, p=0.024), while a higher substage (stage IB-IC vs IA, HR: 8.29, p=0.040) was associated with only a worse OS, and its impact on the RFS was marginal. An initial laparoscopy intervention and higher substage posted significant adverse effects on the prognosis in stage I epithelial ovarian cancer. Important precautions when using laparoscopy for adnexal masses, such as avoiding rupture, applying protection, and submitting frozen sections, are recommended.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979707"}
{"pmid": "20979708", "title": "Operation cancellation at Chang Gung Memorial Hospital.", "content": "Operation cancellation at Chang Gung Memorial Hospital. Roughly 60,000 operations are performed at our medical center every year, so making efficient use of operating rooms (OR) is an important issue. Decreasing the cancellation rate of surgery is one method that could increase efficiency. We reviewed all OR cancellations in 2007 to survey the cancellation rates and causes. The present study was retrospective. Data were collected from the Department of Anesthesiology Quality Assurance Database of Chang Gung Memorial Hospital. We analyzed medical records for cancellations from January 1 to December 31, 2007. Data were analyzed using SPSS 16.0, employing descriptive measures and logistic regression. There were 61855 operations scheduled during this period; 229 were cancelled (0.37%). The mean age of patients in the cancelled group was significantly higher than that in the the non-cancelled group. We found a positive correlation between the cancellation rate and American Society of Anesthesiologists physical status. Cancellations for outpatient surgery were most frequent, as were those in the ophthalmology department. Forty-seven cases were cancelled because of cardiovascular problems; 136 operations were done later after the original cancellation issues were addressed while 11 were done under local anesthesia. Of all causes of cancellation of surgery, 54.1% were avoidable. Medical teams must communicate better with patients and relatives, identify and treat relevant comorbidities, and make adequate preparations for surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979708"}
{"pmid": "20979917", "title": "The need for questionnaires in vascular surgery: the paradigm of carotid revascularization. A joint survey by the International Society for Vascular Surgery (ISVS) and the European Society for Vascular Surgery (ESVS).", "content": "The need for questionnaires in vascular surgery: the paradigm of carotid revascularization. A joint survey by the International Society for Vascular Surgery (ISVS) and the European Society for Vascular Surgery (ESVS).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979917"}
{"pmid": "20979918", "title": "Is the United States the core of the health care universe? Reflections of the recipient of the 2007-2008 E. J. Wylie Traveling Fellowship Award.", "content": "Is the United States the core of the health care universe? Reflections of the recipient of the 2007-2008 E. J. Wylie Traveling Fellowship Award.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979918"}
{"pmid": "20979927", "title": "Microdialysis feasibility investigations with the non-hydrophilic antifungal voriconazole for potential applications in nonclinical and clinical settings.", "content": "Microdialysis feasibility investigations with the non-hydrophilic antifungal voriconazole for potential applications in nonclinical and clinical settings. This study aimed at investigating the feasibility and validity of the microdialysis technique for the non-hydrophilic antifungal voriconazole, in settings for established concentric and new linear catheters. Optimal conditions for application of microdialysis in in vivo studies including steady-state conditions were to be elaborated. For in vitro microdialysis investigations, a robust and easy-to-handle system was developed permitting standardized physiological-like conditions. Various experiments on the influence of flow-rate (0.4 - 10.0 µl/min), voriconazole concentration (1.0 - 50.0 µg/ml) on relative recovery were performed. Additionally, the mass transfer coefficient r of voriconazole was estimated (WinNonlin™). In vitro microdialysis experiments suggested sufficient voriconazole concentrations in the dialysate for (non-)clinical investigations. The stability of voriconazole was confirmed over 10 h (37 °C). A flow-rate dependency was shown (optimum: 2.0 µl/min) and r was estimated to be 0.09 mm/min and 0.11 mm/min for concentric and linear catheters, respectively. Relative recovery in delivery/recovery experiments was independent of the voriconazole concentration ranging from 96.0% to 97.8%/93.8% to 100.2% (CV 1.7%/ 0.5%) indicating unhampered passage of voriconazole through the catheter. Investigations mimicking steady-state suggested voriconazole concentration of 100 - 200 µg/ml for in vivo catheter calibration solutions. The results demonstrate the feasibility and validity of the microdialysis technique in clinically-mimicked settings despite the higher lipophilicity of voriconazole and support the application of the technique in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979927"}
{"pmid": "20979919", "title": "Management of the immature autogenous arteriovenous fistula.", "content": "Management of the immature autogenous arteriovenous fistula. A high-quality autogenous arteriovenous fistula provides the optimal access for hemodialysis. Following initial surgical construction of a fistula, the maturation process is driven by hemodynamic, cellular, and humoral factors that must result in increased blood flow, vessel dilation, and thickening of the vessel wall before the fistula can be successfully used for dialysis needle access. Different demands are placed on each fistula depending on the individual patient's hemodialysis requirements, which must be clearly understood to properly assess and treat the immature fistula. When spontaneous maturation fails to achieve a functional fistula, additional surgical or minimally invasive interventional procedures may be necessary to enhance the maturation process. Various techniques have been reported to achieve successful fistula maturation. The purpose of this article is to review the concepts of fistula maturation and the interventions that may be performed in cases where there is failure to mature spontaneously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979919"}
{"pmid": "20979928", "title": "Sources and predictors of home-kept prescription drugs.", "content": "Sources and predictors of home-kept prescription drugs. To examine the extent of home-kept prescription drugs in the general population and to identify the predictors for a higher number of prescription drugs kept in people's homes. The study included a random stratified sample of 1,000 Slovenian inhabitants. Participants answered a self-administered questionnaire regarding sources and contents of their home pharmacies. The main outcome measure was the presence and the number of home-kept prescription drugs. The response rate was 41%. At least one prescription drug in the home pharmacy was kept by 298 (75.4%) of the respondents, average number of prescription drugs was 3.1 ± 3.3. The majority of the respondents (319, 77.8%) bought the drugs for self-medication in pharmacies. Almost a quarter of the respondents obtained them from relatives and friends (82, 20.0%). Multivariate logistic regression analysis showed that a visit to a clinical specialist in the previous year and high blood pressure were independent predictors for the presence of any home-kept prescription drug. Multivariate linear regression analysis also showed that rural and suburban living areas, a visit to a clinical specialist, a need for a home visit by a doctor in the past year, and the presence of diabetes, high blood pressure, asthma or depression are independent predictors for a higher number of home-kept prescription drugs. Doctors have to take into account that their patients keep several prescription drugs in their home pharmacies. These patients are potential providers to their friends and relatives of potentially unsafe drugs for self-medication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979928"}
{"pmid": "20979923", "title": "Technique of adding a diameter-reducing wire to the modified TX2 fenestrated stent graft.", "content": "Technique of adding a diameter-reducing wire to the modified TX2 fenestrated stent graft. One of the technical limitations of surgeon-modified fenestrated stent grafts is the lack of a diameter-reducing wire, which facilitates catheterization of target branches if there are errors of device design, alignment, or implantation. This article describes a technique of adding a diameter-reducing wire to the modified TX2 fenestrated stent graft for compassionate use in aortic emergencies or high-risk patients who do not have access to manufactured devices. The modified Cook TX2 stent graft was created using reinforced fenestrations with gold nitinol markers. After the TX2 stent was fully unsheathed, one of the nitinol wires located in the inner cannula was withdrawn and redirected externally through and through the fabric of the stent graft. Each Z stent was constrained using the nitinol wire for support and two nonlocking polypropylene loops. The use of a diameter-reducing wire facilitates side branch catheterization by allowing longitudinal and rotational movement to the modified fenestrated stent graft in patients where there is misalignment between the fenestration and the origin of the target vessel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979923"}
{"pmid": "20979922", "title": "Transit-time volume flow measurements in autogenous femorodistal bypass surgery for intraoperative quality control.", "content": "Transit-time volume flow measurements in autogenous femorodistal bypass surgery for intraoperative quality control. The aim of this study was to assess intraoperative transit-time volume flow measurements (VFMs) as a tool for intraoperative evaluation of lower extremity arterial bypass grafts and to predict their patency. We analyzed 273 consecutive patients who had an infrainguinal bypass procedure using the great saphenous vein from 1998 until 2008; 103 had an intraoperative VFM. All intraoperative revisions were recorded and analyzed. Patency and revision rates were compared between those receiving and those not receiving intraoperative VFM. Cox regression was used for analysis of predictors of patency. Primary patency at 1 and 2 years was 75 and 67%, respectively, in patients receiving intraoperative VFM versus 72 and 69% in those without VFM (p  =  .79). In the VFM group, 12% had an immediate revision versus 6% without VFM (p  =  .06). In the VFM group, 4% underwent revision to salvage the bypass within the first postoperative 30 days versus 6% without VFM (p  =  .32). Patency was not associated with the use of VFM. Receiver operating characteristic curve was significant for occlusion at 30 days postoperatively but with a low predictive value (p  =  .019,area under the curve 0.648). VFM may be helpful in selecting bypasses requiring immediate revision to prevent postoperative occlusion. The use of VFM is not significantly associated with patency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979922"}
{"pmid": "20979921", "title": "Staged hybrid repair of thoracoabdominal aortic aneurysm after chronic type B aortic dissection.", "content": "Staged hybrid repair of thoracoabdominal aortic aneurysm after chronic type B aortic dissection. The purpose of this study was to evaluate clinical outcomes of combined endovascular and open techniques to eradicate false lumen dilatation in the visceral aortic segment after type B aortic dissection associated with aortic aneurysm. We reviewed eight patients with distal thoracic and abdominal false lumen dilatation treated with a staged procedure. These included arch debranching as needed, proximal thoracic endovascular repair, and open surgical correction with abdominal aortic replacement of the visceral and infrarenal aorta. False lumen eradication was successful in all patients. There were no operative deaths, and paraplegia or paraparesis occurred in two patients. During a mean follow-up of 30 months, no complications or secondary interventions were necessary. The thoracic false lumen remained thrombosed in all patients, with no evidence of aortic dilatation or stent graft complications. Complete thrombosis and eradication of the false lumen can be achieved through a three-stage repair of chronic type B aortic dissection with aneurysmal dilatation. A prospective randomized trial is needed to establish the viability of this approach versus standard open repair of type II thoracoabdominal aortic aneurysms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979921"}
{"pmid": "20979930", "title": "Imaging inflammation in stroke using magnetic resonance imaging.", "content": "Imaging inflammation in stroke using magnetic resonance imaging. Stroke is the third leading cause of death, after myocardial infarction and cancer, and the leading cause of permanent disability in Western countries. Although anti-inflammatory drugs have shown very promising results in preclinical rodent studies, they appeared to be ineffective against stroke in clinical trials. In this context, non-invasive detection of inflammatory cells after brain ischemia could be helpful (i) to select patients who may benefit from anti-inflammatory treatment, and/or (ii) to target an adequate individualized therapeutic time window. Magnetic resonance imaging (MRI) coupled with injection of iron oxide nanoparticles, a contrast agent taken up by macrophages ex vivo and in vivo, appears to be a promising tool for this purpose. This review focuses on the use of this technique to image inflammation in pre-clinical and clinical studies of stroke. Despite current limitations, MRI of inflammation may become an important tool for the investigation of novel ischemic stroke therapeutics targeting inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979930"}
{"pmid": "20979929", "title": "Pharmacokinetic and tolerability profile of once-daily zibotentan (ZD4054) in Japanese and Caucasian patients with hormone-resistant prostate cancer.", "content": "Pharmacokinetic and tolerability profile of once-daily zibotentan (ZD4054) in Japanese and Caucasian patients with hormone-resistant prostate cancer. To investigate potential differences in zibotentan pharmacokinetics between Japanese and Caucasian patients with hormone-resistant prostate cancer (HRPC) following single and multiple dosing. In the Japanese study, 18 patients received a single dose of zibotentan 5, 10 or 15 mg followed by 72 h washout before 26 days' once-daily dosing. In the Caucasian study, 21 patients received a single dose of zibotentan 5, 10 or 15 mg followed by 72 h washout before 12 days' once-daily dosing. Pharmacokinetic parameters were similar between populations. Absorption of zibotentan was rapid with maximum plasma concentrations typically achieved within 3 h of dosing. Mean clearance, 17.9 and 18.7 ml/min in Japanese and Caucasian patients, respectively (range 7.0 - 36.3 ml/min in Japanese patients and 7.8 - 29.5 ml/min in Caucasian patients) and volume of distribution, 14.0 and 15.6 l for Japanese and Caucasian patients, respectively (range 7.9 - 29.1 l in Japanese patients and 9.6 - 23.8 l in Caucasian patients) were relatively low, and t1/2 was approximately 12 h (range 5.7 - 18.8 h in Japanese patients and 5.0 - 22.9 h in Caucasian patients) following single dosing. Little accumulation was observed following daily dosing and multiple-dose pharmacokinetics were predictable. Exposure levels achieved in some Japanese patients receiving zibotentan 15 mg were higher than those observed in Caucasian patients, however, this may be due to differences in body weight, as exposure levels were similar when data were normalized for body weight. Zibotentan was well tolerated in both populations. There are no clinically relevant differences in the disposition and pharmacokinetics of zibotentan between Japanese and Caucasian patients with HRPC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979929"}
{"pmid": "20979920", "title": "Initial results of a 12-week, institution-based, supervised exercise rehabilitation program for the management of peripheral arterial disease.", "content": "Initial results of a 12-week, institution-based, supervised exercise rehabilitation program for the management of peripheral arterial disease. This study assessed the effectiveness of a 12-week, institution-based, supervised exercise rehabilitation program with atherogenic risk factor modification in improving cardiovascular profile, ambulatory function, and quality of life of patients with peripheral arterial disease (PAD) by comparing pre- and postprogram measurements. Participants were prospectively enrolled. Cardiovascular profile variables, ambulatory function tests, and quality of life questionnaires were evaluated. Of 101 institution-based program participants, 69 completed the 12-session minimum and 47 completed a postprogram evaluation. Mean postprogram results were significantly different from preprogram results, corresponding to improvement, for the following variables: triglyceride levels (p  =  .036), both function tests (p < .001 for both), four of five Walking Impairment Questionnaire measurements, and Intermittent Claudication Questionnaire score (p  = .001). This supervised exercise program improved the cardiovascular profiles, ambulatory function, and quality of life of PAD patients completing the program and is a viable adjunct to drug therapy and surgical intervention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979920"}
{"pmid": "20979932", "title": "Co-prescription of gastroprotective agents in patients taking non-selective NSAIDs or COX-2 selective inhibitors: analysis of prescriptions.", "content": "Co-prescription of gastroprotective agents in patients taking non-selective NSAIDs or COX-2 selective inhibitors: analysis of prescriptions. To evaluate the prevalence of co-prescription of GPAs (proton pump inhibitors - PPIs and H2-receptor antagonists) and non-selective NSAIDs or COXIBs in patients registered under the local health authority (LHA) of Bergamo, a city in the north of Italy. A drug utilization analysis was done using the Bergamo prescription Health Services Electronic Database. All patients aged 35 years or older who had received at least one prescription during 2004 for non-selective NSAIDs and/or COXIBs were divided into three groups: occasional, chronic and new users. Among chronic users, 44.8% were treated with non-selective NSAIDs, 11.6% with COXIBs, and 43.6% with both (mixed NSAIDs). For new users, non-selective NSAIDs were prescribed to 82.7%, COXIBs and mixed NSAIDs to 10.8% and 6.5%. PPIs were co-prescribed to 7.1% of COXIB users and 5.8% of non-selective NSAID occasional users. Among chronic users, the figures were 15.6% and 14%. For new users, prescriptions for COXIBs were associated with less use of GPA for patients who received the first and last prescription for NSAIDs and GPAs on the same day, while for patients who became chronic users COXIBs did not reduce the probability of co-prescription of a GPA: the number of co-prescribed medications and antithrombotics or corticosteroids were independent predictors of GPA use. COXIBs seem to be used in patients at high risk of GI toxicity. However, the fear of GI adverse reactions and the uncertain safety profile of COXIBs leads many physicians to boost the gastroprotection by prescribing a PPI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979932"}
{"pmid": "20979926", "title": "Percutaneous in situ oxygenated pump perfusion of a transplanted kidney during abdominal aortic aneurysm repair.", "content": "Percutaneous in situ oxygenated pump perfusion of a transplanted kidney during abdominal aortic aneurysm repair. The surgical management of aortic aneurysms in kidney transplant patients is a difficult clinical scenario where preservation of the kidney allograft during aortic cross-clamping is paramount. We describe a novel technique for renal protection during abdominal aortic aneurysm repair with in situ oxygenated pump perfusion of the transplanted kidney. A percutaneous approach is used for common femoral artery and vein cannulation and a cardiopulmonary bypass circuit to provide retrograde oxygenated pump perfusion to the transplanted kidney. This technique allows adequate kidney perfusion during warm ischemia and minimizes morbidity by using a percutaneous access technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979926"}
{"pmid": "20979931", "title": "Associations between oxaliplatin-induced peripheral neuropathy and polymorphisms of the ERCC1 and GSTP1 genes.", "content": "Associations between oxaliplatin-induced peripheral neuropathy and polymorphisms of the ERCC1 and GSTP1 genes. Oxaliplatin-induced chronic neuropathy is cumulative and dose-limiting; reliable predictors and determination of the mechanism of this toxic effect are needed. We retrospectively studied 51 Japanese adults with colorectal cancer who had received oxaliplatin-based chemotherapy to explore the pharmacogenetic association between oxaliplatin-induced neuropathy and polymorphisms of the excision repair cross-complementation Group 1 (ERCC1) and glutathione-S-transferases pi 1 (GSTP1) genes. For the ERCC1 C118T polymorphism, Grade 1 chronic neuropathy developed earlier in patients with C/T and T/T genotypes (median number of treatment cycles at onset = 6) than in those with the reference C/C genotype (7 cycles; p = 0.0162 by the generalized Wilcoxon test). For the GSTP1 Ile105Val polymorphism, chronic neuropathy developed earlier in patients with the reference Ile/Ile genotype (6 cycles) than in those with Ile/Val and Val/Val genotypes (9 cycles; p = 0.0321). ERCC1 C118T and GSTP1 Ile105Val polymorphisms were not significantly associated with an increased risk of developing Grade 2 or more severe chronic neuropathy. Our results suggest that ERCC1, C118T and GSTP1 Ile105Val polymorphisms are more strongly related to the time until onset of neuropathy than to the grade of neuropathy. Most likely these polymorphisms influence patients' sensitivity to neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979931"}
{"pmid": "20979925", "title": "Combined endovascular and vascular surgical therapy of a blister-like distal internal carotid aneurysm in a patient with a right-sided aortic arch.", "content": "Combined endovascular and vascular surgical therapy of a blister-like distal internal carotid aneurysm in a patient with a right-sided aortic arch. Blood blister-like aneurysms (BBAs) are rare but challenging to treat owing to their fragile, thin walls and poorly defined necks. A right-sided aortic arch is an uncommon congenital cardiac anomaly with an estimated incidence of only 0.1% and presents a challenge to intubation at vessels above the aortic arch. This represents an extremely rare case of a BBA at the left internal carotid artery with a right-sided aortic arch treated with combined endovascular and vascular surgical therapy. We report the case and provide a short review of the relevant literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979925"}
{"pmid": "20979924", "title": "Extracranial internal carotid artery pseudoaneurysms after kinking reconstruction.", "content": "Extracranial internal carotid artery pseudoaneurysms after kinking reconstruction. The purpose of this report is to describe our experience of infected false aneurysm treatment following internal carotid artery (ICA) reconstruction. Five and 6 years before admission, bilateral reconstruction was done because of ICA kinking at a local health center. The patient was symptomless for 5 years but later became partially symptomatic (dizziness, vertigo, and visibly bilateral neck pulsatile masses). On routinely performed ultrasonography and multislice scanner examinations, the bilateral ICA pseudoaneurysms were revealed. The final treatment was surgery and aneurysmal sac resection followed by end-to-end arterial reconstruction. A right-sided wound swab was positive; Staphylococcus aureus was cultured. Antibiotics were administered: teicoplanin (Targocid) 800 mg as an initial dose followed by 400 mg maintenance doses over the following 4 days. After 1 month, left ICA reconstruction was done and a wound swab showed staphylococcal infection as well. At the 12-month follow-up, the patient was doing well; cerebral vascularization was well preserved. Infected false aneurysms are rare complications following carotid artery reconstruction. Aneurysmal sac resection and arterial reconstruction with end-to-end anastomosis or autologous saphenous vein are recommended. A wound swab is mandatory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979924"}
{"pmid": "20979934", "title": "Effects of probenecid on the pharmacokinetics of mizoribine and co-administration of the two drugs in patients with nephrotic syndrome.", "content": "Effects of probenecid on the pharmacokinetics of mizoribine and co-administration of the two drugs in patients with nephrotic syndrome. Probenecid (PRB) is an agent that reduces the systemic level of uric acid, and has the ability to inhibit the renal tubular secretion of agents that are co-administered with it. In this study, we evaluated the effects of PRB co-administered with mizoribine (MZR) on the pharmacokinetics (PK) of MZR in 12 patients with nephrotic syndrome. The elimination rate constant (kel) was used as an indicator of changes in the PK of MZR when the secretion of MZR was inhibited by co-administration of PRB, in order to determine the extent to which MZR was influenced by PRB. In 4 of the 12 patients studied, kel decreased and the biological half-life (t1/2) of MZR was prolonged when co-administered with PRB, in comparison with the values when MZR was used alone, thus revealing that the PK of MZR was influenced by PRB. Co-administration of PRB with MZR appears to be effective in prolonging the biological half-life of MZR and enhancing its effect in patients with nephrotic syndrome, although further studies will be required to determine the optimal dosage of PRB and renoprotective effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979934"}
{"pmid": "20979933", "title": "Pharmacokinetic study of the oral administration of procaterol hydrochloride hydrate 50 µg in healthy adult Japanese men.", "content": "Pharmacokinetic study of the oral administration of procaterol hydrochloride hydrate 50 µg in healthy adult Japanese men. The pharmacokinetics of procaterol, a selective beta2-adrenergic agonist with a high intrinsic efficacy in man, could not be determined in humans when the drug was launched because of the low therapeutic dose and the low sensitivity of the analytical methods available at the time. However, a recently established analytical method using LC-MS/MS has been refined to enable the determination of the pharmacokinetic profile of procaterol and its metabolites in humans. Procaterol hydrochloride hydrate 50 µg was administered orally to 8 healthy adult Japanese men. Plasma and urine samples collected from the subjects were analyzed by use of LC-MS/MS for procaterol and its metabolites. Following the oral administration of procaterol hydrochloride hydrate 50 µg, the plasma concentration of procaterol reached a Cmax of 136.4 pg/ml at ~1.44 h post-dose. The mean apparent terminal elimination half-life was ~3.83 h. DM-251 and DM-252, glucuronides of the optical isomers of procaterol, were the main metabolites and both were present in plasma at higher levels than procaterol in the plasma. The 24 h urinary excretion rates of unchanged procaterol, DM-251 and DM-252 were 15.7%, 12.4% and 11.2% of the procaterol administered, respectively. This study describes the pharmacokinetic profiles of procaterol and its metabolites following the oral administration of procaterol hydrochloride hydrate 50 µg. Procaterol and its glucuronides were found at high levels in the plasma and urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979933"}
{"pmid": "20979936", "title": "Different persistence on initial basal supported oral therapy in Type 2 diabetics is associated with unequal distributions of insulin treatment regimens under real-life conditions in Germany.", "content": "Different persistence on initial basal supported oral therapy in Type 2 diabetics is associated with unequal distributions of insulin treatment regimens under real-life conditions in Germany. Results from a representative German database and from two German health services research studies revealed an unequal distribution between basal supported oral therapy (BOT) and basal-bolus therapy (ICT) regimens in Type 2 diabetics treated with either insulin glargine (GLA) or human insulin (Neutral Protamine Hagedorn; NPH). This study assesses whether this unequal distribution could be caused by a different persistence on the initial BOT regimen. A Markov model was developed simulating the transition from BOT to ICT during a treatment course of 10 years. Data on persistence with BOT were obtained from the IMS® Disease Analyzer database. The model cohort consisted of German statutorily insured Type 2 diabetics starting a BOT either with insulin glargine or NPH insulin at a ratio of 1 : 1. The number of Type 2 diabetics who switched from BOT to ICT differed between the two groups: After 2 years, 53% of glargine-treated patients and 31% of NPH-treated patients continued the BOT. After 6.5 years, all NPH-treated patients had switched to ICT. However, complete transition to ICT of glargine-treated patients occurred 1.75 years later. In the first quarter of Year 3, the model simulation resulted in BOT : ICT ratios comparable to those found in the real-world settings for GLA- and NPH-treated patients. The simulation indicates that the persistence on the initial basal supported oral therapy is associated with the resulting BOT : ICT ratio. Therefore, the unequal distribution between BOT and ICT of Type 2 diabetics treated with either insulin glargine or NPH insulin might be caused by different persistence on the initial BOT regimen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979936"}
{"pmid": "20979935", "title": "Night-time bioavailability of levodopa/carbidopa/entacapone is higher compared to controlled-release levodopa/carbidopa.", "content": "Night-time bioavailability of levodopa/carbidopa/entacapone is higher compared to controlled-release levodopa/carbidopa. Controlled-release levodopa/carbidopa (CR-LC) is often used to provide prolonged control of night-time motor symptoms in patients with Parkinson's disease (PD). Levodopa/carbidopa/entacapone (LCE) provides higher bioavailability of levodopa compared with levodopa/carbidopa formulations and has been shown to be effective in PD patients with wearing-off symptoms. The aim of this study was to compare the bioavailability of levodopa after a single evening dose (administered at 10 p.m.) of LCE 200 or CR-LC 200. This was an open-label, randomized, crossover study in healthy subjects. The main pharmacokinetic (PK) parameters were AUC, Cmax, C6h and t1/2 of levodopa. A single evening dose of LCE 200 was associated with significantly better bioavailability compared with CR-LC 200. In line with increased bioavailability of levodopa, LCE 200 induced more nausea. The results of this study demonstrate that a single bedtime dose of LCE 200 provides higher bioavailability of levodopa compared to CR-LC 200.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979935"}
{"pmid": "20979937", "title": "Factors influencing valproate pharmacokinetics in children and adults.", "content": "Factors influencing valproate pharmacokinetics in children and adults. The aim of the present study was to build population pharmacokinetic models for the clearance of valproate (VPA) in 2 separate populations of Serbian patients with epilepsy, children and adults. Analysis was performed using 65 and 63 steady-state concentrations of VPA collected from 58 children and 60 adult epileptic patients, respectively. Mean values for total body weight and age were 27.07 ± 13.08 kg and 7.21 ± 3.63 years in the pediatric population, and 69.67 ± 15.60 kg and 33.97 ± 16.41 years in the adult population. The one-compartment model with first order elimination and without absorption was used from the PREDPP (Prediction for Observation Population Pharmacokinetics) library of NONMEM software. The derived final models show that VPA clearance increased with total body weight of patients in both populations. However, the carbamazepine comedication was the main determinant of the final model in children whereas phenobarbitone comedication was the most important factor in the adult population. The magnitudes of these effects were +0.159 lh-1 and +0.539 lh-1 for carbamazepine and phenobarbitone, respectively. A significant decrease in interindividual and intraindividual variability was observed in the target populations. The pharmacokinetic models obtained were validated in groups of 15 epileptic patients, each showing good predictive performance of the model. The derived models describe well VPA clearance in terms of characteristics of Serbian pediatric and adult epileptic patients, offering a basis for rational individualization of VPA dosage regimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979937"}
{"pmid": "20979938", "title": "Stroke after treatment with bortezomib and dexamethasone in a Chinese patient with extramedullary relapse of multiple myeloma.", "content": "Stroke after treatment with bortezomib and dexamethasone in a Chinese patient with extramedullary relapse of multiple myeloma. Thromboembolic complications commonly occur in patients with multiple myeloma (MM). The risk of such complications may be elevated by the use of immunomodulatory agents such as thalidomide and lenalidomide as initial therapy for MM. However, arterial thrombosis after treatment with bortezomib is rare. Herein we report a case of a 70-year-old Chinese male patient with extramedullary relapse of MM. After treatment with bortezomib and dexamethasone he developed a nonfatal thrombotic stroke. Administration of bortezomib and dexamethasone was then discontinued and he obtained partial remission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979938"}
{"pmid": "20979939", "title": "Erythropoietin production by distal nephron in normal and familial amyloidotic adult human kidneys.", "content": "Erythropoietin production by distal nephron in normal and familial amyloidotic adult human kidneys. the kidney is the major site of erythropoietin production. Many efforts have been made to identify renal erythropoietin-producing cells. Previous studies showed conflicting results, but the predominant localization reported was the peritubular interstitial and tubular epithelial cells. This study was conducted to identify the erythropoietin-producing cells in renal biopsies from 10 cadaveric donors and 45 patients with familial amyloidosis ATTR V30M, thirteen of them with anemia. Familial amyloidosis Type I (FAP-I) is a genetic disorder caused by a transthyretin (TTR) protein variant presenting a single amino acid substitution of methionine for valine at position 30 of the polypeptide chain (TTR V30M). Anemia in FAP-I is associated with inappropriately low serum erythropoietin levels. erythropoietin expression was detected by in situ hybridization (ISH) and confirmed by laser capture microdissection followed by PCR. Renal segments were identified by immunohistochemistry. erythropoietin was mainly expressed by epithelial distal tubular cells and collecting tubules and additionally, in a few biopsies, by glomerular cells. A similar expression pattern was observed in donors and FAP-I patients. No increased mRNA erythropoietin expression was found in anemic patients, all of them presenting only a slight expression in medulla and cortex. these results suggest the distal nephron as the major site of erythropoietin production, and support the notion that an inappropriate erythropoietin production is the cause of anemia in familial amyloidosis ATTR V30M.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979939"}
{"pmid": "20979940", "title": "Nutritional markers, not markers of bone turnover, are related predictors of bone mineral density in chronic peritoneal dialysis patients.", "content": "Nutritional markers, not markers of bone turnover, are related predictors of bone mineral density in chronic peritoneal dialysis patients. this study evaluated the factors associated with bone mineral density (BMD) in chronic peritoneal dialysis (CPD) patients. in this cross-sectional study in 91 stable CPD patients, BMD was measured using dual-energy X-ray absorptiometry. Markers of bone turnover (iPTH, osteocalcin, bone alkaline phosphatase, serum C-telopeptide), 25-hydroxy (OH) vitamin D3 and nutritional markers (prealbumin, nPNA, BMI) were measured by standard techniques. of the 91 patients, 48 were female and 22 (24%) had Type 2 diabetes. Mean age of the patients was 52.7, and patients had been on PD for about 44 months. For the lumbar spine (LS) and femoral neck (FN), the mean T-scores were -1.19 ± 1.53 and -1.24 ± 1.01, respectively, and the mean Z-scores were -0.78 ± 1.33 and -0.40 ± 0.92, respectively. Using the WHO-based criteria, osteopenia (-2.5 < T-score < -1.0) at the LS and FN was observed in 37 (41%) and 48 (53%) patients, respectively, and osteoporosis (T-score <= -2.5) at the LS and FN was observed in 15 (17%) and 6 (7%) patients, respectively. LS T-score was positively correlated with BMI (r = 0.40, p < 0.001) and albumin (r = 0.29, p = 0.005), and FN T-score was positively correlated with albumin (r = 0.40, p < 0.001), prealbumin (r = 0.38, p < 0.001), age (r = -0.32, p = 0.002) and BMI (r = 0.29, p < 0.006). Markers of bone turnover were not associated with BMD. In multiple linear regression models, independent predictors of FN T-score were age, BMI, albumin and prealbumin (r(2) = 0.259, F = 6.23, p < 0.001), whereas BMI was the only independent predictor of LS T-score (r(2) = 0.24, F = 6.63, p < 0.001). nutritional markers, not markers of bone turnover, are correlated predictors of BMD in CPD patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979940"}
{"pmid": "20979941", "title": "Relationship between carnosinase gene CNDP1 leucine repeat polymorphism and the clinical outcome of Chinese PD patients.", "content": "Relationship between carnosinase gene CNDP1 leucine repeat polymorphism and the clinical outcome of Chinese PD patients. pre-clinical studies showed that carnosine may have a beneficial cardiovascular effect. We studied the effect of tri-nucleotide repeat (CTGs) polymorphisms in exon 2 of the CNDP1 gene, which codes for carnosinase and is responsible for the degradation of carnosine, on the clinical outcome of Chinese peritoneal dialysis (PD) patients. we studied 442 PD subjects. Genotyping was done by direct sequencing of genomic DNA. Patients were followed for 43.5 ± 16.2 months. the prevalence of 6-6, 5-6, 5-5 and 4-6 CTGs genotypes was 80.3%, 18.6%, 0.9% and 0.2%, respectively. A total of 270 patients (61.1%) developed the primary composite end point during follow-up. The 5-year event-free survival of the 6-6 CTGs and non 6-6 group was 37.1% and 21.3%, respectively (log rank test, p = 0.3). the CTGs polymorphism of the CNDP1 gene does not affect survival of Chinese PD subjects. The role of carnosine and CNDP1 gene polymorphism in the pathogenesis of cardiovascular disease requires further study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979941"}
{"pmid": "20979942", "title": "Hemodialysis patients' experience with and attitudes toward the buttonhole technique for arteriovenous fistula cannulation.", "content": "Hemodialysis patients' experience with and attitudes toward the buttonhole technique for arteriovenous fistula cannulation. the buttonhole technique for arteriovenous fistula cannulation has been recommended as an alternative to the rope ladder technique. we compared patients' experiences and hypothesized that patients would prefer the buttonhole technique. in an observational cross-sectional study using a 23-item questionnaire, we surveyed hemodialysis patients at 3 dialysis centers who had previously used the rope ladder technique and were presently using the buttonhole technique for their experiences with and attitudes toward the two techniques. Twelve months later, patients' attitudes were reassessed. 26 patients met inclusion criteria. On a scale of 0 (not at all satisfied) to 10 (very satisfied), patients reported a mean satisfaction with the buttonhole technique of 8.5 ± 1.9. 96% of patients said they would recommend it, and 83% reported that the buttonhole technique was easier for the nurses to use. Fewer patients reported fistula infiltration with the buttonhole technique (12% vs. 59%, p = 0.008). Twelve months later, 18 of 23 patients (78%) still dialyzing in the study units remained satisfied with the buttonhole technique. patients reported a high level of satisfaction, fewer complications, and a positive attitude about suggesting the buttonhole technique to other patients. Our findings support the recommendation for its more widespread use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979942"}
{"pmid": "20979943", "title": "A single-center experience of preemptive anticoagulation for patients with risk factors for allograft thrombosis in renal transplantation.", "content": "A single-center experience of preemptive anticoagulation for patients with risk factors for allograft thrombosis in renal transplantation. to review our single-center experience of preemptive anticoagulation for the prevention of allograft thrombosis in patients with hypercoagulable states. this is a retrospective cohort study. Included subjects were first-time kidney allograft recipients transplanted between 2003 and 2007 at a single center, with hypercoagulable states: prior venous thromboembolism, multiple vascular access thromboses, or identifiable thrombophilia. The predictor variable was preemptive anticoagulation and outcome variable was allograft thrombosis. Other risk factors for allograft thrombosis, characteristics of transplantation, and hemorrhagic complications were also examined. among this high-risk cohort (n = 48), 16 received preemptive anticoagulation and 32 did not. The anticoagulated group included significantly more subjects with identifiable thrombophilia (50.0% vs. 0%; p < 0.001). One subject (6.3%) in the anticoagulated group and 6 (18.8%) without anticoagulation developed allograft thrombosis (p = 0.40). A perinephric hematoma was observed in 5 (31.3%) and 2 (6.3%) with and without anticoagulation, respectively (p = 0.03). preemptive anticoagulation was associated with a non-significant trend towards decreased allograft thrombosis. It may be associated with increased risk of hemorrhage and should be considered cautiously in high-risk patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979943"}
{"pmid": "20979944", "title": "Comparison of estimated glomerular filtration rate (eGFR) using the MDRD and CKD-EPI equations for CKD screening in a large population.", "content": "Comparison of estimated glomerular filtration rate (eGFR) using the MDRD and CKD-EPI equations for CKD screening in a large population. recently, the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) proposed a new equation for estimating glomerular filtration rate (eGFR), which could potentially replace the Modified Diet for Renal Disease Study (MDRD) equation in routine clinical use. Our aim was to evaluate the correlation between them and to compare the prevalence of each CKD stage using these two equations. we measured serum creatinine in 38,188 consecutive patients and calculated eGFR using the CKD-EPI and MDRD equations. We also compared the distribution of CKD stages for both equations. there was very good correlation between eGFR estimated by CKD-EPI and MDRD at values < 60 ml/min × 1.73 m2, but not at higher values. Estimated prevalence of CKD (eGFR < 60 ml/min × 1.73 m2) was 5.9% with CKD-EPI and 7.5% with MDRD. Furthermore, the prevalence of CKD Stage 2 was lower with CKD-EPI (33.8% vs. 49.1%. with MDRD). the use of the CKD-EPI equation results in a lower estimated prevalence of CKD, compared to the MDRD equation. This may have important implications for public health and clinical practice, as well as for future modification of guidelines for laboratories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979944"}
{"pmid": "20979946", "title": "The changing pattern of primary glomerulonephritis in Singapore and other countries over the past 3 decades.", "content": "The changing pattern of primary glomerulonephritis in Singapore and other countries over the past 3 decades. This review of 2,586 renal biopsies over the past 3 decades in Singapore documents the changing pattern of glomerulonephritis (GN) from that of a third world country to that of a developed nation. In the 1st decade, mesangial proliferative glomerulonephritis was the most common form of primary GN, just as it was in the surrounding Asian countries. In the 2nd decade, the prevalence of mesangial proliferative GN decreased with a rise in membranous, GN which is also seen in China and Thailand. In the 3rd decade, there was a dramatic increase in focal sclerosing glomerulosclerosis. This increase reflects aging and obesity in keeping with more developed countries like Australia, India, Thailand and the United States of America. IgA nephritis remains the most common GN. Apart from the geographical influence, other socioeconomic factors play a significant role in the evolution of the renal biopsy pattern. Mesangial proliferative GN remains prevalent in many Asian countries, but in Singapore the prevalence is decreasing just as it is in Japan, Korea and Malaysia. Worldwide, the prevalence of focal sclerosing glomerulosclerosis continues to increase in many countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979946"}
{"pmid": "20979945", "title": "Gastrointestinal sensitivity to soy and milk proteins in patients with IgA nephropathy.", "content": "Gastrointestinal sensitivity to soy and milk proteins in patients with IgA nephropathy. sensitivity to food antigens has been postulated as a contributing factor to the pathogenesis of IgA nephropathy (IgAN). in this study we used a recently developed mucosal patch technique to evaluate rectal mucosal sensitivity to soy and cow's milk (CM) proteins in IgAN patients (n = 28) compared to healthy subjects (n = 18). The rectal mucosal production of nitric oxide (NO) and release of myeloperoxidase (MPO) and eosinophil cationic protein (ECP) were measured. Serum samples were analyzed for IgA and IgG antibodies to alpha-lactalbumin, beta-lactoglobulin, casein and soy. 14 of 28 (14/28) patients experienced a rectal mucosal reaction, measured by increased NO and/or MPO levels, upon rectal challenge with soy and/or cow's milk proteins. The levels of IgG antibodies to alpha-lactalbumin, beta-lactoglobulin and casein were significantly higher in CM sensitive as compared with non-sensitive IgAN patients, whereas the mean serum levels of IgA antibodies were similar. No differences were seen in serum levels of IgA or IgG antibodies to soy. it is concluded that approximately half of our IgAN patients have a rectal mucosal sensitivity to soy or CM, and that an immune reactivity against antigens may be involved in the pathogenesis of IgAN in this subgroup of patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979945"}
{"pmid": "20979947", "title": "Resolution of mesangial light chain deposits 3 years after high-dose melphalan with autologous peripheral blood stem cell transplantation.", "content": "Resolution of mesangial light chain deposits 3 years after high-dose melphalan with autologous peripheral blood stem cell transplantation. A 52-year-old woman was admitted to our hospital for treatment of nephrotic syndrome. Funduscopic findings showed fundal hemorrhage and soft exudates, and serologic analysis showed a monoclonal serum component that was identified as Bence Jones protein-k type. A bone marrow biopsy showed diffuse proliferation of atypical plasma cells, while a renal biopsy showed diffuse and nodular mesangial proliferation. Immunohistochemical staining confirmed the presence of k chains along the glomerular basement membrane and in mesangial areas. The patient was diagnosed as multiple myeloma (Bence Jones k type) with light chain deposition disease (LCDD). After high-dose melphalan and autologous peripheral blood stem cell transplantation (PBSCT), the multiple myeloma and nephrotic syndrome were in complete remission; her renal function was improved, but a renal biopsy performed 6 months after PBSCT showed the persistence of diffuse and nodular lesions. By contrast, a renal biopsy performed 3 years later showed complete resolution of the diffuse and nodular mesangial proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979947"}
{"pmid": "20979948", "title": "Acute neurological presentation due to copper deficiency in a hemodialysis patient following gastric bypass surgery.", "content": "Acute neurological presentation due to copper deficiency in a hemodialysis patient following gastric bypass surgery. Acquired copper deficiency has been recently recognized as a cause of myelopathy, and has been reported to occur many years after gastric bypass surgery performed to aid weight reduction in morbidly obese patients. We report a case of a young woman treated by hemodialysis who presented with acute neurological symptoms 5 months after gastric bypass surgery for severe obesity. She had symptoms and signs of cerebellar, spinal cord and peripheral nerve disease, which improved following parenteral copper supplementation. Now that gastric bypass surgery is being offered to morbidly obese hemodialysis patients, this case highlights the importance of monitoring copper levels in hemodialysis patients following gastric bypass surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979948"}
{"pmid": "20979949", "title": "Histopathological manifestations of membranoproliferative glomerulonephritis and glomerular expression of plasmalemmal vesicle-associated protein-1 in a patient with polycythemia vera.", "content": "Histopathological manifestations of membranoproliferative glomerulonephritis and glomerular expression of plasmalemmal vesicle-associated protein-1 in a patient with polycythemia vera. Only a few cases of various glomerulonephropathies have been reported in patients with polycythemia vera. We report the case of a 72-year-old female with polycythemia vera in whom renal biopsy examination showed membranoproliferative glomerulonephritis (MPGN)-like lesion and glomerular expression of plasmalemmal vesicle-associated protein-1 (PV-1), a marker of glomerular capillary remodeling after injury. Prior to admission to our hospital for nephrotic syndrome, she had received hydroxyurea and phlebotomy. On admission, she was hypertensive with pretibial edema, hepatosplenomegaly, massive proteinuria (6.14 g/day), low serum albumin (2.9 g/dl), high fibrinogen, fibrin/fibrinogen degradation products and thrombomodulin levels, but with normal serum creatinine and complement levels. Microscopic examination of a renal biopsy demonstrated MPGN-like features with double contour and mesangial interposition. Electron microscopy showed subendothelial deposits, platelets attached to glomerular capillary walls and fibrin deposition. Immunofluorescence study identified IgM deposition along part of the capillary wall and mesangium. CD42b-positive platelets and megakaryocytes were detected in glomerular capillaries, accompanied with increased expression of platelet-derived growth factor receptor b and thrombomodulin in the mesangium and glomerular capillary, respectively. PV-1 was expressed along the glomerular capillary. Anti-platelet and anticoagulant combination therapy, together with the use of anti-hypertensive agents and hydroxyurea, resulted in improvement of the nephrotic syndrome. The findings suggested that activated platelets, enhanced coagulation state and endothelial damage may contribute to glomerulonephropathy associated with polycythemia vera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979949"}
{"pmid": "20979950", "title": "An 8-month-old boy with congenital fibromuscular dysplasia presenting with shock caused by sudden renal hemorrhage.", "content": "An 8-month-old boy with congenital fibromuscular dysplasia presenting with shock caused by sudden renal hemorrhage. Fibromuscular dysplasia (FMD) is a non-atheromatous, non-inflammatory, multifocal segmental angiopathy. FMD is the most common cause of pediatric renovascular hypertension. Aneurysmal formation of the main renal artery and distal branches is a rare complication of FMD in infancy. We report an 8-month-old boy with FMD presenting with shock caused by sudden renal hemorrhage that necessitated removal of one kidney. A diagnosis of renovascular hypertension resulting from intimal type FMD with aneurysmal formation was made on the basis of the presence of hypertension, elevation of PRA and aldosterone activity, pathological findings and the results of renal angiography. Our findings suggest that it is therefore necessary to consider FMD with aneurysmal formation as a possible cause of hypertension and renal hemorrhage in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979950"}
{"pmid": "20979952", "title": "Prevalence of the antiheparin-platelet factor 4 antibody in hemodialysis (HD) patients and its effects upon dialysis access.", "content": "Prevalence of the antiheparin-platelet factor 4 antibody in hemodialysis (HD) patients and its effects upon dialysis access.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979952"}
{"pmid": "20979953", "title": "CKD in disadvantaged populations: the uncomfortable realities.", "content": "CKD in disadvantaged populations: the uncomfortable realities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979953"}
{"pmid": "20979951", "title": "Pseudoaldosteronism with increased serum cortisol associated with pneumonia, hypouricemia, hypocalcemia, and hypophosphatemia.", "content": "Pseudoaldosteronism with increased serum cortisol associated with pneumonia, hypouricemia, hypocalcemia, and hypophosphatemia. We describe here the interesting case of a 73-year-old hypertensive man with pseudoaldosteronism. He had been taking glycyrrhizin at a dose of 75 mg/day for 12 years because of mild liver damage, but had never experienced any previous symptoms associated with hypokalemia. He was referred to our hospital because of hypokalemic tetraparesis and rhabdomyolysis. At that time, we noted mineralocorticoid excess characterized by hypokalemia due to urinary K loss, exacerbation of hypertension due to increased tubular Na reabsorption, metabolic alkalosis, and suppression of both plasma renin activity and plasma aldosterone concentration. His urinary free cortisol excretion rate and the urinary ratio of free cortisol to free cortisone were markedly elevated. Thus we diagnosed pseudoaldosteronism that was related to the long-term use of glycyrrhizin. When he developed pseudoaldosteronism, he also contracted pneumonia, and exhibited elevated levels of serum cortisol and creatinine clearance (CCr) as well as hypouricemia, hypocalcemia, and hypophosphatemia. All normalized after the recovery from pneumonia and the administration of spironolactone. The extracellular volume expansion associated with increased tubular Na reabsorption by the aldosterone-sensitive distal nephron and the resulting increase in CCr caused an inhibition of proximal tubular reabsorption of uric acid, Ca, and inorganic phosphate, leading to their renal loss and therefore hypouricemia, hypocalcemia, and hypophosphatemia, respectively. In this patient, the increased circulating cortisol associated with the stress of inflammation caused by pneumonia triggered the development of pseudoaldosteronism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979951"}
{"pmid": "20979955", "title": "Burden of disease - prevalence and incidence of renal disease in India.", "content": "Burden of disease - prevalence and incidence of renal disease in India. Chronic Kidney Disease (CKD) burden is increasing worldwide. In developing countries like India, limited financial resources and lack of infrastructure put a severe strain on existing health policies in the light of the increasing burden of CKD. The exact prevalence of CKD in India is not known due to lack of adequate data recording systems both in the Government and insurance sectors. Recently with the support of the Indian society of Nephrology, a CKD registry has been formed with the hope of generating adequate information about CKD patients in India. Here we have reviewed various published studies on the magnitude of CKD in India. Three studies which have been carried out in different parts of India have been reviewed to examine the prevalence of CKD, which ranges from 0.79% to 1.4%. The incidence of End Stage Renal Disease was estimated to be 181 per million population in 2005 in central India. Many more such efforts are needed across our country in order to determine the exact burden of CKD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979955"}
{"pmid": "20979954", "title": "Latin American Dialysis and Renal Transplant Registry: 2008 report (data 2006).", "content": "Latin American Dialysis and Renal Transplant Registry: 2008 report (data 2006). Between 1991 and 2006, the Latin American Dialysis and Renal Transplantation Registry collected data from 20 countries (Argentina, Brazil, Bolivia, Chile, Colombia, Costa Rica, Cuba, Ecuador, El Salvador, Guatemala, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Puerto Rico, Dominican Republic, Venezuela and Uruguay). Access to RRT was universal in Argentina, Brazil, Chile, Cuba, Puerto Rico, Venezuela and Uruguay, all countries belonging to the medium-high or high income group. Data about patients on renal replacement therapy (RRT) were supplied by national affiliates or the Registry's Coordination Committee. Transplant data were gathered and shared with the Latin American and Caribbean Society of Transplantation. RRT prevalence increased from 162 patients per million population (pmp) in 1991 to 478 pmp in 2005 and 473 pmp in 2006 (59.2% hemodialysis, 20.4% peritoneal dialysis and 20.4% with a functioning kidney allograft). Countries with the highest prevalence were Puerto Rico (1,148.9 pmp), Uruguay (924.5 pmp) and Chile (907.6 pmp). Latin America's (LA) incidence increased from 27.8 pmp in 1992 to 188 pmp in 2006. The LA Kidney transplant rate increased from 3.7 pmp in 1987 to 15,4 pmp in 2006, and 166 combined transplants - kidney and another organ, mainly pancreas - were performed. In the medium-high income group 2006, (Argentina, Brazil, Chile, Costa Rica, Cuba, Mexico, Panama, Uruguay, Venezuela) the prevalence rate was 534.8 pmp vs. 289.5 pmp in the middle-low income group. The transplant rate was 18.4 pmp in the medium-high income group vs. 7 pmp in the middle-low group (p < 0.01). RRT incidence and prevalence continue to grow steadily. Access to RRT is universal only in some countries included in the medium-high or high income group. It is imperative to accomplish the goal of making RRT available to all who need it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979954"}
{"pmid": "20979956", "title": "Burden of end-stage renal disease in sub-Saharan Africa.", "content": "Burden of end-stage renal disease in sub-Saharan Africa. To review prevalence, causes and management of end-stage renal disease (ESRD) in sub-Saharan Africa (SSA). Review of literature and data. Approximately 70% of the least developed countries of the world are in SSA. Rapid urbanization is occurring in many parts of the continent, contributing to overcrowding and poverty. While infections and parasitic diseases are still the leading cause of death in Africa, non-communicable diseases are coming to the forefront. There is a continuing \"brain drain\" of healthcare workers (physicians and nurses) from Africa to more affluent regions. There are large rural areas of Africa that have no health professionals to serve these populations. There are no nephrologists in many parts of SSA; the numbers vary from 0.5 per million population (pmp) in Kenya to 0.6 pmp in Nigeria, 0.7 pmp in Sudan and 1.1 pmp in South Africa. Chronic kidney disease affects mainly young adults aged 20 - 50 years in SSA and is primarily due to hypertension and glomerular diseases. HIV- related glomerular disease often presents late, with patients requiring dialysis. Diabetes mellitus affects 9.4 million people in Africa. The prevalence of diabetic nephropathy is estimated to be 6 - 16% in SSA. The current dialysis treatment rate is < 20 pmp (and nil in many countries of SSA), with in-center hemodialysis the modality of RRT for the majority. Transplantation is carried out in a few SSA countries: South Africa, Nigeria, Mauritius and Ghana, with most of the transplants being living donor transplants, except in South Africa where the majority are from deceased donors. Chronic kidney disease care is especially challenging in SSA, with large numbers of ESRD patients, inadequate facilities, funding and support.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979956"}
{"pmid": "20979957", "title": "Renal replacement therapies for end-stage renal disease in North Africa.", "content": "Renal replacement therapies for end-stage renal disease in North Africa. Despite population, social and cultural similarities between the countries in the region, large differences in the management of end-stage renal disease (ESRD) are found. This reflects the varying policies and health priorities of different countries, leading to differences in terms of renal replacement therapies (RRT) facilities. Hemodialysis remains the most frequent modality. Demographic and epidemiological transition has lead to an increased incidence of diabetes mellitus and arterial hypertension, but glomerulonephritis and interstitial nephropathies remain important causes of ESRD in the region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979957"}
{"pmid": "20979958", "title": "Current burden and probable increasing incidence of ESRD in China.", "content": "Current burden and probable increasing incidence of ESRD in China. To illustrate the incidence and prevalence of ESRD in mainland China, and estimate future trends. The Chinese Society of Blood Purification (CSBP) produced a survey form. The form was designed for use at the facility level, rather than at the patient level. The data were those prevailing at the end of 2008, i.e., the total number of patients at the end of 2007 and the number of new patients during the year 2008; numbers of males and females and each of the age groups; numbers of diabetes, hypertension, polycystic kidney disease, chronic interstitial nephritis, etc. as primary cause of ESRD; and numbers of cardiovascular disease, stroke, infection, etc. as primary cause of death. The forms were distributed to each dialysis facility, and returned to CSBP for analysis. The point prevalence of ESRD patients on maintenance hemodialysis (MHD) at the end of 2007 and 2008, and the annual incidence in 2008 were calculated. The primary cause of ESRD and primary cause of death were also reported. Among 31 provinces and/or regions, 27 responded. At the end of 2007, there were totally 65,074 ESRD patients on MHD or PD; the point prevalence was estimated to be 51.7 per million population (pmp) around mainland China. The number increased to 102,863 at the end of 2008; point prevalence increased to 79.1 pmp. The annual increasing rate of prevalence was 52.9%. The number of new ESRD patients was 45,423; the annual incidence was 36.1 pmp in the year 2008. The main causes of ESRD were glomerulonephritis (45%), diabetes (19%), hypertension (13%), polycystic kidney disease (2%) and others or unknown (20%). The main cause of death was cardiovascular (31.0%), stroke (20.3%), infection (19.9%) and others (28.8%). Although the prevalence was relatively low compared with other Asian regions, the incidence of MHD was high. Mainland China is anticipating an increasing burden of ESRD in the near future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979958"}
{"pmid": "20979959", "title": "Burden of disease - prevalence and incidence of ESRD in selected European regions and populations.", "content": "Burden of disease - prevalence and incidence of ESRD in selected European regions and populations. Rates of renal replacement therapy (RRT) vary markedly between Eastern and Western European countries. This review aims to establish the characteristics of healthcare systems and renal services that are independently associated with rates of initiation of RRT in these countries. The incidence of RRT varied from 12 to 455 per million populations (pmp); the only general population indicator independently associated with RRT incidence was aged 65+. Economic and financial conditions could also play an important role. Gross Domestic Product (GDP) per capita and the proportion of GDP spent on healthcare independently predicted RRT incidence. Each increase in hemodialysis (HD) facilities and competition between providers is associated with higher RRT incidence. In this context, macroeconomic and potentially modifiable renal service organizational factors appear more important determinants of provision of RRT than measurable medical factors. The economic, financial or medical conditions could also play an important role in treatment strategy. The proportion of patients receiving HD, peritoneal dialysis (PD) or transplantation shows marked variation in Europe. The East Europeans use more HD and less RTx as compared to West Europeans; the use of PD is similar. Treatment of anemia and mineral metabolism disorders also varies from one region to another. The mean baseline hemoglobin level and the prevalence of patients reaching this value are higher in West Europeans. Regarding mineral metabolism, the percent of patients achieving all four parameters (Ca, P, CaxP and PTH) was also higher in Western Europe. The adherence to EBPG (European Best Practice Guidelines) was also higher in these countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979959"}
{"pmid": "20979960", "title": "Incidence and treatment of ESRD among indigenous peoples of Australasia.", "content": "Incidence and treatment of ESRD among indigenous peoples of Australasia. Indigenous people in Australia and New Zealand experience rates of ESKD several times higher than non-indigenous people. This relative rate is highest among people aged 45 - 54 for Aboriginal Australians, and 65 - 74 years for Maori. The majority of this is driven by diabetic nephropathy. Both groups have lesser utilization of transplantation as a renal replacement therapy than non-indigenous comparators, and lesser utilization of home dialysis modalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979960"}
{"pmid": "20979962", "title": "Hypertension and kidney disease.", "content": "Hypertension and kidney disease. The relationship between chronic kidney disease and hypertension remains enigmatic and a matter of considerable clinical and academic interest, with evidence suggesting that hypertension is both a cause and a consequence of kidney disease. The kidney has a pivotal role in setting the blood pressure in any individual, and this is likely to be related to that individual's sensitivity to salt. The relationship between low birth weight and subsequent hypertension and kidney disease may be predicated on changes in post glomerular phenomena, including sodium transport, although there are differences observed between white and black populations, there being no such clear relationship demonstrable in the latter. Differences in vascular structure may account for some of this variation. There is , by way of example a considerable difference in the risk of death from cardiovascular disease between blacks and Caucasoid populations with renal disease, the former being at greater risk. International moves are now afoot to reduce dietary salt intake. Successful efforts to reduce blood pressure by these or by pharmacological means are likely to reduce death rates, although precise blood pressure targets remain an elusive concept. The possible role of non muscular heavy chain type II isoform A protein which is associated with non diabetic chronic kidney disease in subjects of African ancestry remains to be determined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979962"}
{"pmid": "20979961", "title": "The impact of disadvantage on the development and progression of diabetic kidney disease.", "content": "The impact of disadvantage on the development and progression of diabetic kidney disease. Disadvantaged people include those experiencing economic, social or educational deprivation and, in some cases, those undergoing rapid transition from subsistence to industrial economies. Disadvantaged people worldwide are affected disproportionately by the global epidemic of diabetes. They are also at increased risk of kidney disease attributable to diabetes, and for many, the cost of managing their kidney disease far exceeds their available resources. We review factors associated with disadvantage that may increase the risk of diabetic kidney disease, and the barriers to care that hinder attempts to provide an adequate therapeutic response. A rapidly rising prevalence and magnitude of obesity among children and adults, increasing frequency of intrauterine exposure to diabetes, and inadequate access to healthcare are responsible, in part, for a surge in the frequency of diabetes and, in turn, diabetic kidney disease among disadvantaged people. These factors may also predispose to an earlier onset of diabetes and kidney disease, thereby perpetuating the disadvantage by reducing the earning potential of those affected through illness and disability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979961"}
{"pmid": "20979963", "title": "Glomerulonephritis in disadvantaged populations.", "content": "Glomerulonephritis in disadvantaged populations. Glomerulonephritis (GN) still enjoys a high rank as a cause of chronic kidney disease (CKD) worldwide. Its burden is particularly manifest in disadvantaged populations, with a proportional contribution up to 6-folds compared to that in the USA. There are several overlapping risk factors that render a particular population \"disadvantaged\" in this respect. It is envisaged that these may be categorized into a triad of genetic, climatic and socioeconomic factors. An attempt is made to dissect the impact of each of these factors, which combine in different proportions in different populations thereby explaining regional disparity in the epidemiology, clinical manifestations and outcomes of CKD. The genetic impact is manifest in racial variations in the incidence of GN as a whole, the predominance of FSGS mainly in blacks and IgA nephropathy in Asians, the increased susceptibility to SLE and decreased incidence of IgAN and vasculitis in blacks, with similar trends in other \"subraces\" as Indians, Afro-Caribbean's, Martinique and other indigenous populations. The climatic impact is mainly displayed in the tropics, where the \"rich bioecological environment\" increases the incidence of infection-associated GN, usually proliferative with a few exceptions. The socioeconomic impact, reflecting low national economy in the developing world, modifies the two other arms of the triad according to the level of primary care, efficiency of the referral system and adequate management of primary infections as well as associated glomerular injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979963"}
{"pmid": "20979964", "title": "Risk factors for the development of chronic kidney disease with HIV/AIDS.", "content": "Risk factors for the development of chronic kidney disease with HIV/AIDS. A review of the prevalence and risk factors for chronic kidney disease (CKD) in HIV infection. A review of published literature. High risk for development of chronic kidney disease with HIV infection are black race, CD4 count < 200 cells/mm3, HIV RNA levels > 4,000 copies/ml, family history of CKD and presence of diabetes mellitus, hypertension or hepatitis C co-infection. In 2004, the risk of developing ESRD was reported as 50 times higher in HIV-infected African-Americans than in HIV-infected whites and in 2007, African Americans accounted for nearly 90% of ESRD attributed to HIVAN. Once CKD was established, African-Americans were 18 times more likely to progress to ESRD than whites and their decline in GFR was six times more rapid than white subjects. The prevalence of CKD with HIV infection was 3.5 - 4.7% in 31 European countries, Israel and Argentina, and 1.1 - 5.6% Brazil; 18% Switzerland; 27% India and 12.3% Iran. Reported prevalence of CKD in HIV-infected patients in sub-Saharan Africa ranges from 6 - 48.5%. Few renal biopsy studies have been performed. In South Africa, HIVAN was present in variable numbers in three studies, ranging from 5 - 83% and immune complex disease in 21 - 40%. A variation in the MYH9 locus of chromosome 22 has been associated with increased risk for idiopathic FSGS, hypertensive nephrosclerosis and HIVAN and may explain much of the increased risks of ESRD and FSGS among African-Americans. A strong correlation with serum creatinine levels and progression to ESRD in HIV patients has been linked to an index of chronic damage on renal histology. The role of genetics and variations in MYH9 gene loci in renal disease has to be established in other HIV-infected populations. The histological classification for HIV-associated chronic kidney disease requires review, as well as the utility of chronicity scores to evaluate prognosis and response to therapy of HIV-associated kidney disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979964"}
{"pmid": "20979965", "title": "Chronic kidney disease among Aboriginal people living in Canada.", "content": "Chronic kidney disease among Aboriginal people living in Canada. Chronic kidney disease (CKD) poses a significant health burden on Aboriginal communities around the world. High rates of diabetes among Aboriginal Canadians are an important contributing factor to the rising rates of CKD in this population, and diabetes has been the leading cause of kidney failure among Aboriginal patients initiating dialysis in Canada for the last decade. This paper will describe access to, quality of, and outcomes associated with the renal care of Aboriginal people living in Canada. Research shows that rates of CKD are higher among Aboriginal people residing in Canada, and that despite remote residence location, use of peritoneal dialysis is substantially lower than in white patients. Similarly, although mortality rates among Canadian hemodialysis patients are similar for Aboriginals and for whites, Aboriginal patients have substantially reduced access to kidney transplantation. A concerted effort to lower rates of CKD in this population is needed. Changes in healthcare policy that successfully translate into healthcare provider and patient level improvements in access to and the quality of care will be needed to significantly reduce the risk of CKD and progression to kidney failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979965"}
{"pmid": "20979966", "title": "Kidney disease in Maori and Pacific people in New Zealand.", "content": "Kidney disease in Maori and Pacific people in New Zealand. To highlight the population demographics and socio-economic status of Maori and Pacific people in New Zealand, and relate this to their relative incidence and prevalence of kidney disease, relative access to renal replacement therapies and provide a comparison of their outcomes relative to non-Maori/non-Pacific people with kidney disease in New Zealand. A review was carried out of relevant New Zealand Statistics and Health data, literature on kidney disease in New Zealand including reports of the Australian and New Zealand Dialysis and Transplant Registry and further analysis of the New Zealand Diabetic Cohort Study. There are large differences in the incidence of microalbuminuria, glomerulonephritis and hypertension amongst Maori and Pacific people in comparison to others. There is a 3.5 fold higher relative incidence of Maori and Pacific patients commencing renal replacement therapy. Identified associations with CKD include an increased incidence of obesity, smoking and poverty relative to other members of the population. Maori and Pacific people are less likely to be transplanted and have a reduced graft survival. Maori and Pacific people have a higher incidence of chronic kidney disease and end-stage renal failure in comparison to the rest of the population with poorer outcomes. The causes are likely to be multi-factorial with poverty an important contributor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979966"}
{"pmid": "20979967", "title": "Disparities in end-stage renal disease care in South America.", "content": "Disparities in end-stage renal disease care in South America. South America is one of the most heterogeneous regions in the world regarding ethnical composition and socioeconomic development level. Our aim was to analyze the status of end-stage renal disease (ESRD) management in the Portuguese-speaking and Spanish-speaking countries of South America. Data were collected using a survey sent to the Society of Nephrology of each country, and complemented with data available in the Latin American Dialysis and Transplant Registry or personal communication with collaborators within the nephrology societies. Most of South America countries have a hybrid of public and private healthcare system. Universal access to renal replacement therapy (RRT) is provided in Argentina, Brazil, Chile, Uruguay and Venezuela which comprise nearly 73% of South America population. The expenditure on health per capita varies from nearly US$ 200 per year in Bolivia to more than US$ 1,600 per year in Argentina. The prevalence of patients on RRT varies from 95 pmp. in Paraguay and 924 pmp in Chile. There is an important association between the prevalence of diabetes and the number of patients on RRT. Older people also are at a higher risk of developing ESRD. The rapid aging of the population and a higher prevalence of diabetes will probably translate into a burden of ESRD in the future. It is to be hoped that political and economical stability in the region can ease the adoption of universal access to ESRD treatment in all South American countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979967"}
{"pmid": "20979968", "title": "Racial differences in chronic kidney disease (CKD) and end-stage renal disease (ESRD) in the United States: a social and economic dilemma.", "content": "Racial differences in chronic kidney disease (CKD) and end-stage renal disease (ESRD) in the United States: a social and economic dilemma. Chronic kidney disease (CKD), defined as an eGFR < 60 ml/min/1.73 m², affects up to 25% of the United States population. In addition, it is estimated that approximately 6% of the population have early evidence of CKD and will likely progress to end stage renal disease (ESRD) in the near future. Further, ESRD is more common in many ethnic minorities, with African-Americans having the highest rates of treated ESRD, closely followed by Hispanic Americans, when compared to non- Hispanic White persons. Although African-Americans with CKD are more likely to die than non-Hispanic White persons with CKD, these trends reverse once progression to ESRD is established. The reasons for the disparities in the prevalence and incidence of CKD, ESRD, and mortality are unclear, but likely involve a complex interaction of socioeconomic, environmental and genetic factors. This review highlights current data pertaining to the social and economic impact of ethnic differences in the prevalence and incidence of CKD and ESRD in the United Stated. It is hoped that highlighting the current trend of kidney related health disparities will not only lead to an improved understanding of these issues, but also more informed research agendas, that are ultimately aimed at alleviating ethnic differences in kidney health outcomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979968"}
{"pmid": "20979969", "title": "Racial minority groups on dialysis in Europe: a literature review.", "content": "Racial minority groups on dialysis in Europe: a literature review. To provide an overview of the existing data on non-Caucasian dialysis patients within Europe, and to explore whether these data confirm differences between non-Caucasian and Caucasian dialysis patients that were found in other parts of the world. A query consisting of the combination \"dialysis\", \"ethnicity\", and \"Europe\" was applied in PubMed, EMBASE, Web of Science, CINAHL, and the Cochrane Library. Ten papers were included in this study. Studies from the United Kingdom (UK) and the Netherlands confirm the higher incidence of end-stage renal disease (ESRD) in non-Caucasians. In other European countries these findings were not confirmed. In studies from the UK, the Netherlands, and Spain a younger age at initiation of dialysis treatment for non-Caucasians compared to Caucasians was reported, this is also found in non-European studies. Regarding comorbid conditions at the start of renal replacement therapy (RRT), vascular disease was less common, while diabetes was more common among non-Caucasians compared to Caucasians. Large non-European studies also demonstrated less vascular disease among non-Caucasians initiating RRT than among Caucasians. The survival advantage for non-Caucasian compared to Caucasian RRT patients is confirmed in one large study from the UK and in a Dutch study. Reasons for the better survival of non-Caucasians are not understood completely. Only a few studies are available on non-Caucasian dialysis patients in Europe. The available data confirm findings of other studies throughout the world on racial differences on dialysis. More research is needed to understand the higher incidence and better survival in non-Caucasian patients, and also in countries where there are currently no relevant data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979969"}
{"pmid": "20979970", "title": "Kidney health in the Middle East.", "content": "Kidney health in the Middle East. Chronic kidney disease (CKD) is a common and costly health problem in the Middle East. The incidence of CKD is still unknown, and the incidence of end-stage renal disease (ESRD) is estimated at 100 - 140 incident cases per million population in the Middle East countries. Most of the available statistics about prevalence are of treated ESRD. Published population-based studies for incidence and prevalence of CKD and ESRD are still lacking in most of the Middle East countries. This negatively affects the health planning and effectiveness of preventive and therapeutic measures in the region. The prevalence of renal replacement therapy varies among the different countries in the Middle East. The infrastructure for these services is also variable among these countries and affects the outcome, which as yet cannot be measured accurately. The low gross national income of the Middle East countries is a major factor in negating the implementation of research, planning, and improvement of the services for CKD patients. To overcome the obstacles for the renal services in the Middle East countries, the constraints on health expenditure need to be surmounted, which is not an easy task, and related appropriately to the gross national income. Awareness within the medical community and the public at large about the advances of therapeutic and preventive measures is also an important factor for progress toward better kidney health in the Middle East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979970"}
{"pmid": "20979971", "title": "Acute kidney injury as a risk factor for chronic kidney diseases in disadvantaged populations.", "content": "Acute kidney injury as a risk factor for chronic kidney diseases in disadvantaged populations. Acute kidney injury (AKI) is considered to be a potential cause for developing chronic kidney disease (CKD); on the other hand, CKD predisposes to AKI. The lack of adequate epidemiological data makes it difficult to determine if AKI induces CKD in less developed countries. The etiology of AKI in rich populations, in whom sophisticated surgery, interventional radiology and oncology treatments are usually the cause of AKI, is very different from that of disadvantaged populations, where the origin of AKI is associated with endemic infections, obstetric problems, poisons, toxins and natural disasters. Any conclusions extrapolated from these two settings should be treated with caution. Moreover, people living in disadvantaged conditions are usually much younger than those in rich areas and this age factor could facilitate total recovery of renal function after AKI if treatment based on an adequate supply of water, rehydration and anti-infectious measures were provided. In the small segment of the population of less developed countries having an income per capita similar to that observed in the developed countries, the long-term outcome of AKI should also be expected to be similar. New data coming from two single centers analyzing only the long-term outcome of acute tubular necrosis (ATN) patients, with a normal or near normal renal function prior to the AKI episode, coincide in reporting a requirement for chronic dialysis among the surviving patients of 2%. If these data are confirmed, the importance of AKI as cause of CKD should be reconsidered, both in developed and less developed countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979971"}
{"pmid": "20979972", "title": "Hypovitaminosis D, neighborhood poverty, and progression of chronic kidney disease in disadvantaged populations.", "content": "Hypovitaminosis D, neighborhood poverty, and progression of chronic kidney disease in disadvantaged populations. In the United States, there are significant racial disparities in the incidence and prevalence of end-stage renal disease. The disparities are greatest for the Blacks and the magnitude of disparity is significantly greater than is evident from the incidence and prevalence data of end-stage renal disease - early stage chronic kidney disease is less common in Blacks and during that stage, mortality rate is significantly higher for that racial group. Recent studies have identified a genetic predisposition for non-diabetic renal disease among Blacks. However, genetic factors explain only part of the higher risk and the racial disparities are a result of a complex interplay of biology and sociology. Herein we focus on two factors and their role in explaining the higher risk for progression of chronic kidney disease among Blacks - one biologic (vitamin D deficiency) and one sociologic (neighborhood poverty). A greater Understanding of these factors is important in order to reduce the racial disparities in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979972"}
{"pmid": "20979973", "title": "Management of chronic kidney disease: primary health-care setting, self-care and multidisciplinary approach.", "content": "Management of chronic kidney disease: primary health-care setting, self-care and multidisciplinary approach. End-stage renal disease (ESRD) is a growing problem, particularly in developing countries. Factors closely related with lifestyle and dietary habits that negatively affect kidney function are rarely modified by isolated medical intervention. Therefore, the present study was designed to determine the effect of an educational program with a multidisciplinary health-care approach supported by self-help groups on the lifestyle and dietary habits of patients at high risk of developing chronic kidney disease (CKD). 51 patients with overweight/obesity, 45 with hypertension and 88 with Type 2 diabetes mellitus (DM2) from a Family Medicine Unit, who had failed to meet clinical practice recommendations, were studied over 6 months. Patients received educational intervention guided by a multidisciplinary health team for 4 weeks (including topics such as emotional management, nutritional patterns, exercise and health-related problems). Reinforcement of goals and group dynamics were performed every 3 months. Additionally, self-help groups were constituted during the first month, and functioned with free activities, selected by patients and supported by the health team, for the duration of the study. A lifestyle questionnaire was administered at baseline and the end of the study; clinical and biochemical evaluations were performed every 3 months. Baseline lifestyle and dietary habits were unhealthy in all groups, particularly with regard to diet and exercise, and clinical and biochemical variables were concordant with inadequate achievement of clinical practice recommendations. After 6 months experience within this program, many of the negative lifestyle characteristics significantly improved. All groups reported a notable improvement in nutritional and exercise habits, as well as in management of the emotions. Only diabetic and hypertensive patients significantly improved the knowledge of their disease and adherence to treatment. None of the groups managed to reduce smoking or to cut their alcohol intake habits; however, relatively few participants had displayed these behaviors at the start of the study. Compared to baseline, all the groups significantly reduced body mass index and waist circumference. Additionally, diabetics and overweight/ obese patients significantly reduced blood glucose and increased GFR, and hypertensive patients significantly decreased systolic blood pressure and tended, although not significantly, to increase GFR. Remarkably, all these changes were independent of drug treatment, because none of the therapeutic interventions that had been formerly prescribed by family physicians had been significantly changed by the end of the follow-up in any of the groups. The implementation of educational strategies comprising multiple interventions for patients, guided by health professionals (multidisciplinary teams including primary doctors, dietitians, nurses, social workers), and probably supported by self-help groups, may be very helpful in modifying negative lifestyle and dietary habits. Educational interventions by both doctors and patients should be adopted concurrently and may help to control the enormous and growing problem of ESRD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979973"}
{"pmid": "20979974", "title": "Distribution of volumes of individual glomeruli in kidneys at autopsy: association with age, nephron number, birth weight and body mass index.", "content": "Distribution of volumes of individual glomeruli in kidneys at autopsy: association with age, nephron number, birth weight and body mass index. Glomerular hypertrophy occurs in a number of normal and pathological states. Glomerular volume in kidneys at autopsy is usually indirectly derived from estimates of total glomerular mass and nephron number, and provides only a single value per kidney, with no indication of the range of volumes of glomeruli within the kidney of any given subject. We review findings of the distribution of volumes of different glomeruli within subjects without kidney disease, and their correlations with age, nephron number, birth weight and body mass index (BMI). The study describes findings from autopsy kidneys of selected adult white males from the Southeast USA who had unexpected deaths, and who did not have renal scarring or renal disease. Total glomerular (nephron) number and total glomerular volume were estimated using the disector/fractionator combination, and mean glomerular volume (Vglom) was derived. The volumes of 30 individual glomeruli (IGV) in each subject were determined using the disector/Cavalieri method. IGV values were compared by categories of age, nephron number, birth weight and BMI. There was substantial variation in IGV within subjects. Older age, lower nephron number, lower birth weight and gross obesity were associated with higher mean IGV and with greater IGV heterogeneity. High Vglom and high IGVs were associated with more glomerulosclerosis. However, amongst the generally modest numbers of sclerosed glomeruli, the pattern was uniformly of ischemic collapse of the glomerular tuft. There was no detectable focal segmental glomerular tuft injury. In this series of people without overt renal disease, greater age, nephron deficit, lower birth weight and obesity were marked by glomerular enlargement and greater glomerular volume heterogeneity within individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979974"}
{"pmid": "20979975", "title": "Is there a need for early detection programs for chronic kidney disease?", "content": "Is there a need for early detection programs for chronic kidney disease? The aims of this paper are to examine whether early detection programs are needed to assist in detecting and managing chronic kidney disease (CKD). It draws on existing material which indicates that CKD and its precursor risk factors or illnesses such as hypertension, diabetes mellitus and HIV infection are very clearly major challenges faced by health systems worldwide. This paper evaluates whether CKD meets the epidemiological criteria to justify early screening. More compelling evidence is becoming available which indicates that the prevalence of CKD is significant in both developing and developed countries and that CKD can be easily detected and treated with only small changes to existing practice and this may be improved through screening programs. A brief evaluation of the challenges of establishing early detection programs is provided, as well as an examination of the capacity which exists for establishing such programs. It concludes that, despite the lack of randomized studies, these programs appear to provide an opportunity to integrate CKD management with common chronic illnesses and, through this approach, provide clinical and cost-effective management of both CKD and cardiovascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979975"}
{"pmid": "20979977", "title": "Prevention of CKD in Guatemala.", "content": "Prevention of CKD in Guatemala. The rapidly growing burden of chronic kidney diseases (CKD) is a major public health problem that will stretch the healthcare system of all countries, especially those not yet industrialized. Guatemala has a population of approximately 14 million, of which 60% are younger than 20 years. It is estimated that only 35% of Guatemalan patients with CKD Stage 5 (ESRD) are diagnosed and treated. Therefore, the cost of death and disability due to CKD in this young population is particularly profound. CKD programs have to compete with many demands (often viewed in the short term as more urgent or widespread) for finite healthcare resources. FUNDANIER (Foundation for Children with Kidney Diseases) has been the instrument that facilitated changes in the Guatemalan health system, in order to establish a comprehensive Pediatric Nephrology program. FUNDANIER is the first local initiative to provide comprehensive prevention and management of kidney disease in children and adolescents in Guatemala. Through an agreement with the National Health Authorities, FUNDANIER is involved in the primary, secondary and tertiary prevention of CKD in the pediatric population. This might be a model applicable in other developing countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979977"}
{"pmid": "20979979", "title": "Social experience among vulnerable populations: conflicts and negotiations between chronic patients and their doctors seen as a challenge to medical practice.", "content": "Social experience among vulnerable populations: conflicts and negotiations between chronic patients and their doctors seen as a challenge to medical practice. This article attempts to explore the impact of a chronic illness, end-stage renal disease, on the management of every day life between the actors involved: lay people, the affected children and their families and the medical personnel. The focus is on the nature and the process of interaction between these parties which are confronted from the onset of the illness with fundamental uncertainty concerning length of survival and the reliability of sophisticated technology such as dialysis techniques and transplantation. Within the framework of the organization of this serious illness, such interaction is concretized in the form of certain tasks to be accomplished. These constitute medical work which combines to shape the social relationships between lay people and professionals into confrontation. First, information was gathered from direct observation and fieldwork in two Units of Pediatric Nephrology located in two different hospitals in Paris. Fieldwork was followed by surveys using semi-structured interviews carried out among patients in a private clinic and the unit's personnel, medical and non medical, the families in their homes, and some adolescents in the units. Then questions were raised about strategies and negotiations, in order to reach an agreement as to when a conflict arises. The medical work is carried out in a context of changing situations, constantly called into question by the illness, and thus discovering a social order in which lay people become actors in these new situations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979979"}
{"pmid": "20979978", "title": "Shortage of healthcare workers in sub-Saharan Africa: a nephrological perspective.", "content": "Shortage of healthcare workers in sub-Saharan Africa: a nephrological perspective. The paper assesses the lack of healthcare workers, the consequences, and possible solutions. Review of existing literature and global health reports. The 47 countries of sub-Saharan Africa have a critical shortage of healthcare workers, the deficit amounting to 2.4 million doctors and nurses. There are 2 doctors and 11 nursing/midwifery personnel per 10,000 population, compared with 19 doctors and 49 nursing/midwifery personnel per 10,000 for the Americas, and 32 doctors and 78 nursing/midwifery personnel per 10,000 for Europe. And, whereas there are 28 doctors and 87 nurses/midwifery personnel per 10,000 in high income regions of the world, there are only 5 doctors and 11 nurses/ midwifery personnel per 10,000 in low income regions. The shortage of nephrologists in Africa, and especially sub-Saharan Africa, remains a critical issue, with many countries having < 1 nephrologist per million population; some have no nephrologists at all. The USA, UK, Canada and Australia have benefitted considerably from the migration of nurses and doctors over the past half century. Opportunities for training as well as employment have attracted doctors from many countries to these developed countries. Since 2006, new legislation in the UK has limited the inflow of health workers. Developing countries are also beginning to take steps to mitigate the problem of health worker loss and are developing strategies to both train increasing numbers of different cadres of healthcare worker and also to retain those already working in these countries. The forces of globalization are tending to increase the worldwide movement of all types of professionals, including those working in health care. It is this lack of health workers in developing countries that has been such a major constraint in limiting progress on initiatives such as the HIV \"3 by 5\" and Millennium Development Goals. More specifically, lack of resources, both human and financial, in developing countries has hampered nephrology programs both in the detection and prevention of chronic kidney disease and in the ability of doctors, nurses and other nephrological personnel to provide acute/chronic dialysis and transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979978"}
{"pmid": "20979976", "title": "A comprehensive cooperative project for children with renal diseases in Nicaragua.", "content": "A comprehensive cooperative project for children with renal diseases in Nicaragua. In low-income countries renal diseases generally and chronic kidney disease (CKD) in particular represent a wide-spread and often underdiagnosed clinical problem. The aim of the cooperative project between the pediatric nephrology units of Milan, Italy, and Managua, Nicaragua was to improve the diagnosis and treatment of renal diseases and CKD in Nicaraguan children. When the project started, in 2000, there were many constraints in human and material resources in the Children's Hospital in Managua. Since 2001, a specialized Unit of Pediatric Nephrology and Urology has developed, offering free of charge basic clinical assistance to hospitalized children, and training abroad of the whole staff. Shared protocols, renovation of infrastructure and an information technology (IT) program were implemented. In 2003, renal replacement therapy (RRT) for selected children was initiated, along with a network of six department hospitals in 2005 and, in 2007, a CKD prevention program in the most peripheral Health Units, so that 61% of the Nicaraguan pediatric population is now covered by the project. To ensure implementation of the project, applications for funds to Italian private and public institutions were made and a Nicaraguan charity foundation was activated. The Nicaraguan Ministry of Health and the hospital directors were always involved in the plans of the development of the project and accepted the progressive transfer of the costs to the government, throughout the 9-year duration of the project. The IT program, inclusive of a database of children with kidney and other urinary tract (UT) diseases and a web connection between Milan and Managua, was crucial in monitoring the activities and providing epidemiological data, in order to better allocate resources. The clinical activities and the number of children managed in Managua in 2008 are similar to those of pediatric nephrology units worldwide and depict the level of clinical autonomy achieved. The sister-center model of cooperation and the top-down strategy we applied, along with the careful consideration of all the economic, logistic and political issues, were and are the key factors which explain the favorable results of this cooperative project.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979976"}
{"pmid": "20979980", "title": "Access to new drugs for dialysis patients: challenges for indigenous and non-indigenous populations.", "content": "Access to new drugs for dialysis patients: challenges for indigenous and non-indigenous populations. Most dialysis patients are on 5 - 10 medications. The costs of these medications vary widely, ranging from pennies per day for water soluble multivitamins, to several thousand dollars per year for erythropoietin-stimulating agents. In Canada, public funding for drug therapies is undertaken by each province, with wide variability in coverage and on restriction criteria for expensive new drugs. For native Canadians and Inuit, access to drugs is superior to that of other Canadians through a federal program. The Canadian system for drug evaluation, where strict evidence-based medicine (EBM) and comparative effectiveness research (CER) is applied, is instructive and may provide clues to the future from an international perspective. Given the unique challenges in nephrology, it is predicted that access to new drugs and other therapies will be restricted by these evaluation methods. Indeed, it seems desirable for nephrology organizations to respond to this new threat in a pragmatic and balanced way. Part of that response might be a call for exceptional status for dialysis, with adjusted criteria of EBM and CER that would be more suitable, and stimulate innovation and research in nephrology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979980"}
{"pmid": "20979982", "title": "Population differentiation and selective constraints in Pelargonium line pattern virus.", "content": "Population differentiation and selective constraints in Pelargonium line pattern virus. The genomic structure of Pelargonium line pattern virus (PLPV), a tentative member of a proposed new genus within the family Tombusviridae, has been recently determined. However, little is known about the genetic variability and population structure of this pathogen. Here, we have investigated the heterogeneity of PLPV isolates from different origins by sequence analysis of a 1817nt fragment encompassing the movement (p7 and p9.7) and coat protein genes as well as flanking segments including the complete 3' untranslated region. We have evaluated the selective pressures operating on both viral proteins and RNA genome in order to assess the relative functional and/or structural relevance of different amino acid or nucleotide sites. The results of the study have revealed that distinct protein domains are under different selective constraints and that maintenance of certain primary and/or secondary structures in RNA regulatory sequences might be an important factor limiting viral heterogeneity. We have also performed covariation analyses to uncover potential dependencies among amino acid sites of the same protein or of different proteins. The detection of linked amino acid substitutions has permitted to draw a putative network of intra- and interprotein interactions that are likely required to accomplish the different steps of the infection cycle. Finally, we have obtained phylogenetic trees that support geographical segregation of PLPV sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979982"}
{"pmid": "20979983", "title": "Infectious salmon anemia virus--genetics and pathogenesis.", "content": "Infectious salmon anemia virus--genetics and pathogenesis. The infectious salmon anemia virus (ISAV) is the causative agent of the ISA syndrome that affects mainly Atlantic salmon (Salmo salar) and has caused high mortality epidemics in Norway, Scotland, Canada, the United States and Chile. It is classified as an Orthomyxoviridae, its genome is composed of 8 single-strand RNA segments with negative polarity that code for 11 polypeptides. Through functional studies of the coded proteins it has been established that RNA segments 5 and 6 code for a fusion protein and hemagglutinin, respectively, while two polypeptides coded by segments 7 and 8 inhibit interferon induction. The functions of the rest of the possible proteins coded by the viral genome have been assigned by comparison with the corresponding ones of the influenza virus genome. As to its pathogenicity, some growth parameters such as incubation period, resistance to chemical and physical factors, establishment of the infection in other marine species, and dissemination ability among the different organs have been evaluated in several salmonids. Genomic analysis has shown (i) the existence of a high polymorphism region (HPR) in segment 6, and (ii) sequence insertion in segment 5. More than 20 HPR variants have been determined, all originating from HPR0, which is associated with low pathogenicity, while 4 different sequence insertions in segment 5 have not been related with some characteristic of the virus infection. Much progress has been made in the characterization of the virus in 20 years of study, but more detailed knowledge of the specific function of the proteins coded by all the viral genes is still missing, including the pathogenicity mechanism at the molecular level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979983"}
{"pmid": "20979981", "title": "Living related renal transplants with lifelong follow-up. A model for the developing world.", "content": "Living related renal transplants with lifelong follow-up. A model for the developing world. To describe the dynamic of a model of public government partnership for dialysis and transplantation in developing countries. A model was established on the philosophy of public-government partnership to provide an integrated dialysis and transplant service \"Free with dignity\" with lifelong follow-up care and medications. The government provided 50% of funds and the public was motivated to donate the rest. This included affluent individuals, corporations, business houses and the general public. This model has been sustained for the last two decades. In 2008, 655,000 patients were treated at SIUT. Over 600 patients are dialyzed each day with a total of 165,411 dialysis sessions/year. Thus far 2,249 transplants have been performed, 431 in 2008. One- and 5-year graft survival rates were 92% and 85%, respectively. The laboratory performed 4.1 million tests and radiological investigations numbered 164,217. Over $ 6 million were spent on medications. Free services offered by the model have motivated the government to increase its funding from $ 2.1 million in 1998 to $ 10 million in 2008 and the public has matched these figures with total donations exceeding $ 20 million. For transplantation to be successful in developing countries, it has to be made available to the common people who constitute 90% of the population. Our model of public-government partnership has made dialysis and transplantation available to the disenfranchised with lifelong follow-up and medications. Transplantation has become relevant to them, resulting in societal acceptance of transplantation as a preferred mode of therapy. This has motivated society to support both living related and deceased donor programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979981"}
{"pmid": "20979984", "title": "The latest developments in synthetic peptides with immunoregulatory activities.", "content": "The latest developments in synthetic peptides with immunoregulatory activities. In the past few years, many researches have provided us with much data demonstrating the abilities of synthetic peptides to impact immune response in vitro and in vivo. These peptides were designed according to the structure of some important protein molecules which play a key role in immune response, so they act with specific targets. The class I and II MHC-derived peptides inhibit the TCR recognition of antigen peptide-MHC complex. Rationally designed CD80 and CD154-binding peptides block the interaction between cell surface costimulatory molecules on antigen-presenting cells (APCs) and T cells. Some peptides were designed to inhibit the activities of cell signal proteins, including JNK, NF-κB and NFAT. Some peptide antagonists competitively bind to important cytokines and inhibit their activities, such as TNF-α, TGF-β and IL-1β inhibitory peptides. Adhesion molecule ICAM-1 derived peptides block the T cell adhesion and activation. These immunoregulatory peptides showed therapeutic effect in several animal models, including collagen-induced arthritis (CIA), autoimmune cystitis model, murine skin transplant model and cardiac allograft model. These results give us important implications for the development of a novel therapy for immune mediated diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979984"}
{"pmid": "20979985", "title": "Formation of pyrophosphate-like adducts from nerve agents sarin, soman and cyclosarin in phosphate buffer: implications for analytical and toxicological investigations.", "content": "Formation of pyrophosphate-like adducts from nerve agents sarin, soman and cyclosarin in phosphate buffer: implications for analytical and toxicological investigations. Phosphate buffer is frequently used in biological, biochemical and biomedical applications especially when pH is to be controlled around the physiological value of 7.4. One of the prerequisites of a buffer compound among good buffering capacity and pH stability over time is its non-reactivity with other constituents of the solution. This is especially important for quantitative analytical or toxicological assays. Previous work has identified a number of amino alcohol buffers like TRIS to react with G-type nerve agents sarin, soman and cyclosarin to form stable phosphonic diesters. In case of phosphate buffer we were able to confirm not only the rapid hydrolysis of these agents to the respective alkyl methylphosphonates but also the formation of substantial amounts of pyrophosphate-like adducts (phosphorylated methylphosphonates), which very slowly hydrolyzed following zero-order kinetics. This led to a complex mixture of phosphorus containing species with changing concentrations over time. We identified the molecular structure of these buffer adducts using 1D ¹H-³¹P HSQC NMR and LC-ESI-MS/MS techniques. Reaction rates of adduct formation are fast enough to compete with hydrolysis in aqueous solution and to yield substantial amounts of buffer adduct over the course of just a couple of minutes. Possible reaction mechanisms are discussed with respect to the formation and subsequent hydrolysis of the pyrophosphate-like compounds as well as the increased rate of hydrolysis of the nerve agent to the corresponding alkyl methylphosphonates. In summary, the use of phosphate buffer for the development of new assays with sarin, soman and cyclosarin is discouraged. Already existing protocols should be carefully reexamined on an individual basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979985"}
{"pmid": "20979986", "title": "Structure-based in silico model profiles the binding constant of poorly soluble drugs with β-cyclodextrin.", "content": "Structure-based in silico model profiles the binding constant of poorly soluble drugs with β-cyclodextrin. Cyclodextrin inclusion complexation technique is the key method to enhance the solubility and absorption of poorly soluble drugs in the early development stage, and thus it is essential to predict the binding constant between drug molecules and cyclodextrin. Structure-based in silico model was constructed for a data set of 86 poorly soluble drugs and used to profile the binding constant of drug-β-cyclodextrin inclusion complex. The stepwise regression was employed to select the optimum subset of the independent variables. The in silico model was built by the multiple linear regression method and validated by the residual analysis, the normal Probability-Probability plot and Williams plot. For the entire data set, the R(2) and Q(2) of the model were 0.78 and 0.67, respectively. The results indicated that the fitted model is robust, stable and satisfies all the prerequisites of the regression models. The chemical space position and important contributors were compared between selected drug molecules and organic compounds available in the literature. It was suggested that the binding behavior of drug molecules with β-CD should differ from that of the common organic compounds. Focusing on structurally diverse drugs, the in silico model can be used as an efficient tool to rapidly screen the drug-β-cyclodextrin inclusion complex stability and to rationally design the new drug delivery system of poorly soluble drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979986"}
{"pmid": "20979989", "title": "Distinguishing non-spatial from spatial biases in visual selection: neuropsychological evidence.", "content": "Distinguishing non-spatial from spatial biases in visual selection: neuropsychological evidence. Recently, it has been shown that patients with visual extinction can show enhanced awareness of contralesional stimuli that match the contents of working memory [Soto, D., & Humphreys, G.W. (2006). Proceedings of the National Academy of Sciences, USA, 103, 4789-4792]. Here we investigate whether these effects extend to cases where the working memory cue is verbal rather than visual (Study 1), and we show that non-spatial cues can overcome problems in spatial disengagement in patients, and this can affect the first eye movement made in search (Study 2). We discuss the implications of the data for understanding the relations between the cueing of attention from visual and conceptual information held in working memory and the cueing of spatial attention, and for understanding the relations between non-spatial and spatial biases in selection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979989"}
{"pmid": "20979988", "title": "Why were Turks unwilling to accept the A/H1N1 influenza-pandemic vaccination? People's beliefs and perceptions about the swine flu outbreak and vaccine in the later stage of the epidemic.", "content": "Why were Turks unwilling to accept the A/H1N1 influenza-pandemic vaccination? People's beliefs and perceptions about the swine flu outbreak and vaccine in the later stage of the epidemic. This study investigated the acceptability of the A/H1N1 influenza vaccination and related factors among 1137 adults in the later stage of the A/H1N1 outbreak in Turkey. Having already been vaccinated or intending to get vaccinated were related to trust in the vaccine effectiveness, perceived risk of the side effects, and benefits of getting vaccinated. Perceived long term consequences of the A/H1N1 infection, perceptions of the A/H1N1 information in media, and barriers for getting vaccinated were related to intention whereas anticipated epidemic situation in Turkey, being chronically ill, and being not married were related to having already been vaccinated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979988"}
{"pmid": "20979987", "title": "Evaluation of Psn, HmuR and a modified LcrV protein delivered to mice by live attenuated Salmonella as a vaccine against bubonic and pneumonic Yersinia pestis challenge.", "content": "Evaluation of Psn, HmuR and a modified LcrV protein delivered to mice by live attenuated Salmonella as a vaccine against bubonic and pneumonic Yersinia pestis challenge. We evaluated the ability of Yersinia pestis antigens HmuR, Psn and modified forms of LcrV delivered by live attenuated Salmonella strains to stimulate a protective immune response against subcutaneous or intranasal challenge with Y. pestis CO92. LcrV196 is a previously described truncated protein that includes aa 131-326 of LcrV and LcrV5214 has been modified to replace five key amino acids required for interaction with the TLR2 receptor. Psn is the outer membrane receptor for the siderophore, yersiniabactin, and the bacteriocin, pesticin. Mice immunized with Salmonella synthesizing Psn, LcrV196 or LcrV5214 developed serum IgG responses to the respective Yersinia antigen and were protected against pneumonic challenge with Y. pestis. Immunization with Salmonella synthesizing Psn or LcrV196 was sufficient to afford nearly full protection against bubonic challenge, while immunization with the strain synthesizing LcrV5214 was not protective. Immunization with Salmonella synthesizing HmuR, an outer membrane protein involved in heme acquisition in Y. pestis, was poorly immunogenic and did not elicit a protective response against either challenge route. These findings indicate that both Psn and LcrV196 delivered by Salmonella provide protection against both bubonic and pneumonic plague.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979987"}
{"pmid": "20979991", "title": "The role of tumor necrosis factor-α for interleukin-10 production by murine dendritic cells.", "content": "The role of tumor necrosis factor-α for interleukin-10 production by murine dendritic cells. In the present study, we examined the role of tumor necrosis factor (TNF) in interleukin (IL)-10 production by dendritic cells (DCs) using bone-marrow derived DCs from wild type (WT) and TNF-α knockout (TNF-α(-/-)) mice. Toll-like receptor (TLR) stimulation induced substantial level of IL-10 production by WT DCs, but significantly low level of IL-10 production by TNF-α(-/-) DCs. In contrast, no significant difference was detected in IL-12 p40 production between WT and TNF-α(-/-) DCs. Addition of TNF-α during TLR stimulation recovered the impaired ability of TNF-α(-/-) DCs for IL-10 production. This recovery appeared to be associated with an activation of extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and phosphatidylinositol 3-kinase/Akt following the TNF-α addition. Blocking these kinases significantly inhibited IL-10 production by TNF-α(-/-) DCs stimulated with TLR ligands plus TNF-α. Thus, TNF-α may be a key molecule to regulate the balance between anti-inflammatory versus inflammatory cytokine production in DCs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979991"}
{"pmid": "20979990", "title": "Correlation of biological properties with glucan-binding protein B expression profile in Streptococcus mutans clinical isolates.", "content": "Correlation of biological properties with glucan-binding protein B expression profile in Streptococcus mutans clinical isolates. Streptococcus mutans is known to be a primary causative agent of dental caries and its surface proteins have been investigated to specify their association with its virulence. Amongst those, 4 glucan-binding proteins (Gbps) are considered to be important factors due to their glucan-binding properties, of which GbpB has been shown to participate in cell-wall construction and cell separation. We examined clinical isolates of S. mutans collected from the oral cavities of Japanese and Finnish subjects, and focused on the association of their GbpB expression profiles and biological properties related to virulence. Western blot analysis of GbpB expression by the isolates revealed a variety of patterns. Strains that showed single and multiple bands were used to designate S and M type strains, respectively, whilst those with no GbpB expression were classified as N type. The distribution of GbpB expression patterns was shown to be quite different between the Japanese and Finnish isolates. Furthermore, the chain length and doubling time of the N type in both populations were significantly longer than those of the other types. Our results suggest variations in S. mutans GbpB expression patterns, which may have relationships with the virulence of S. mutans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979990"}
{"pmid": "20979992", "title": "Perceptual load influences auditory space perception in the ventriloquist aftereffect.", "content": "Perceptual load influences auditory space perception in the ventriloquist aftereffect. A period of exposure to trains of simultaneous but spatially offset auditory and visual stimuli can induce a temporary shift in the perception of sound location. This phenomenon, known as the 'ventriloquist aftereffect', reflects a realignment of auditory and visual spatial representations such that they approach perceptual alignment despite their physical spatial discordance. Such dynamic changes to sensory representations are likely to underlie the brain's ability to accommodate inter-sensory discordance produced by sensory errors (particularly in sound localization) and variability in sensory transduction. It is currently unknown, however, whether these plastic changes induced by adaptation to spatially disparate inputs occurs automatically or whether they are dependent on selectively attending to the visual or auditory stimuli. Here, we demonstrate that robust auditory spatial aftereffects can be induced even in the presence of a competing visual stimulus. Importantly, we found that when attention is directed to the competing stimuli, the pattern of aftereffects is altered. These results indicate that attention can modulate the ventriloquist aftereffect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979992"}
{"pmid": "20979995", "title": "Proteomic analysis of endometrium in fertile women during the prereceptive and receptive phases after luteinizing hormone surge.", "content": "Proteomic analysis of endometrium in fertile women during the prereceptive and receptive phases after luteinizing hormone surge. In fertile women the patterns of proteome during the prereceptive (day 2 after LH surge) and receptive (day 7 after LH surge) phases were analyzed by two-dimensional fluorescence difference gel electrophoresis and mass spectrometry. A total of 31 differentially expressed proteins (17 up-regulated and 14 down-regulated) were identified between the two phases, which is helpful in understanding the biological mechanisms underlying human endometrial receptivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979995"}
{"pmid": "20979997", "title": "A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study.", "content": "A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study. This pilot study investigates the role of luteal supplementation with recombinant LH in an attempt to reverse the poor reproductive outcome previously noticed after GnRH-agonist triggering of final oocyte maturation for IVF. Similar implantation rates were achieved with the novel recombinant LH luteal supplementation scheme compared with the standard luteal P protocol (25.0% vs. 26.7%, respectively). No cases of ovarian hyperstimulation syndrome (OHSS) were noticed in either group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979997"}
{"pmid": "20979996", "title": "Polycystic ovary syndrome: an ancient disorder?", "content": "Polycystic ovary syndrome: an ancient disorder? Polycystic ovary syndrome (PCOS) appears to be an ancient disorder, which has persisted in human evolution despite reduced fecundity because of the benefits to affected women such as greater sturdiness and improved energy utilization, a rearing advantage for their children and kin, and a reduction in the risk of perinatal mortality. This raises the possibility that gene variants that are eventually found to be associated with PCOS will be similar across ethnic groups and races.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979996"}
{"pmid": "20979998", "title": "Craniofacial morphometric variation and the biological history of the peopling of Sardinia.", "content": "Craniofacial morphometric variation and the biological history of the peopling of Sardinia. The aim of this work is to explore the pattern of craniofacial morphometric variation and the relationships among five prehistoric Sardinian groups dated from Late Neolithic to the Nuragic Period (Middle and Late Bronze Age), in order to formulate hypotheses on the peopling history of Sardinia. Biological relationships with coeval populations of central peninsular Italy were also analysed to detect influences from and towards extra-Sardinian sources. Furthermore, comparison with samples of contemporary populations from Sardinia and from continental Italy provided an indication of the trend leading to the final part of the peopling history. Finally, Upper Palaeolithic and Mesolithic samples were included in the analyses to compare the prehistoric Sardinians with some of their potential continental ancestors. The analysis is based on multivariate techniques including Mahalanobis D(2) distance, non-parametric multidimensional scaling (MDS) and principal component analysis (PCA). The results showed the tendency to progressive differentiation between Sardinian groups and peninsular Italian groups, with the possible exception of a discontinuity showed by the Bonnànaro (Early Bronze Age) Sardinian sample. Several aspects of the morphological results were found to agree with the current genetic evidence available for the present-day Sardinian population and a Nuragic sample: (1) biological divergence between the Sardinian and peninsular Italian populations; (2) similarity/continuity among Neolithic, Bronze Age and recent Sardinians; (3) biological separation between the Nuragic and Etruscan populations; (4) contribution of a Palaeo-Mesolithic gene pool to the genetic structure of current Sardinians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979998"}
{"pmid": "20979999", "title": "Fractional order ultra low-speed position servo: improved performance via describing function analysis.", "content": "Fractional order ultra low-speed position servo: improved performance via describing function analysis. In a reference of the previous work, a new systematic design method for fractional order proportional and derivative (FOPD) controller is proposed for a class of typical second-order plants. Simulation and experimental results in the reference show that, the dynamic performance and robustness with the designed FOPD controller outperforms that with the optimized traditional integer order proportional integral (IOPI) controller at normal speed. Furthermore, it is found that, for the ultra low-speed position tracking with a significant friction effect, the tracking performance using the designed FOPD controller is much better than that using the optimized IOPI controller. However, the reason of this advantage is unclear. In this paper, using the describing function method and Bode plots analysis, the observed advantage of the designed FOPD controller over the optimized IOPI controller, for the nonlinear low-speed position tracking system with friction effect, is explained with the theoretical analysis. This explanation for the priority of the designed FOPD controller is consistently demonstrated by the extended experimental results in this paper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979999"}
{"pmid": "20980000", "title": "Evaluation of subclinical atherosclerosis by computed tomography coronary angiography and its association with risk factors in familial hypercholesterolemia.", "content": "Evaluation of subclinical atherosclerosis by computed tomography coronary angiography and its association with risk factors in familial hypercholesterolemia. Increasing age and cholesterol levels, male gender, and family history of early coronary heart disease (CHD) are associated with early onset of CHD in familial hypercholesterolemia (FH). Assess subclinical atherosclerosis by computed tomography coronary angiography (CTCA) and its association with clinical and laboratorial parameters in asymptomatic FH subjects. 102 FH subjects (36% male, 45 ± 13 years, LDL-c 280 ± 54 mg/dL) and 35 controls (40% male, 46 ± 12 years, LDL-c 103 ± 18 mg/dL) were submitted to CTCA. Plaques were divided into calcified, mixed and non-calcified; luminal stenosis was characterized as >50% obstruction. FH had a greater atherosclerotic burden represented by higher number of patients with: plaques (48% vs. 14%, p=0.0005), stenosis (19% vs. 3%, p=0.015), segments with plaques (2.05 ± 2.85 vs.0.43 ± 1.33, p=0.0016) and calcium scores (55 ± 129 vs. 38 ± 140, p=0.0028). After multivariate analysis, determinants of plaque presence were increasing age (OR=2.06, for age change of 10 years, CI95%: 1.38-3.07, p<0.001) and total cholesterol (OR=1.86, for cholesterol change by 1 standard deviation, CI95%: 1.09-3.15, p=0.027). Coronary calcium score was associated with the presence of stenosis (OR=1.54; CI95%: 1.27-1.86, p<0.001, for doubling the calcium score). Male gender was directly associated with the presence of non-calcified plaques (OR: 15.45, CI95% 1.72-138.23, p=0.014) and inversely with calcified plaques (OR=0.21, CI95%: 0.05-0.84, p=0.027). Family history of early CHD was associated with the presence of mixed plaques (OR=4.90, CI95%: 1.32-18.21, p=0.018). Patients with FH had an increased burden of coronary atherosclerosis by CTCA. The burden of atherosclerosis and individual plaque subtypes differed with the presence of other associated risk factors, with age and cholesterol being most important. A coronary calcium score of zero ruled out obstructive disease in this higher risk population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980000"}
{"pmid": "20980001", "title": "Lifestyle and cardiovascular risk factors in 2001 child-parent pairs: the PEP Family Heart Study.", "content": "Lifestyle and cardiovascular risk factors in 2001 child-parent pairs: the PEP Family Heart Study. Genes and environment are the main determinants of cardiovascular disease (CVD) risk factor clustering in families. Since individual risk factor profiles are easily predicted within families, we examined whether CVD risk factors are affected by lifestyle factors in these families. Nutrition, physical activity, and smoking habits were assessed in 2001 biological child-parent pairs from 852 families participating in the Prevention Education Program (PEP). Height, weight, body mass index, waist circumference, blood pressure, and fasting lipid levels were measured. Within-family associations were calculated using generalized estimating equations (GEE). Fathers possessed the most adverse risk profile. Daily energy consumption above the recommended levels was higher in children (daughters +35.4%, sons +26.7%) than in parents (fathers +15.7%, mothers +10.6%). Higher energy consumption was significantly associated with hypertension in mothers (OR 2.5) and in fathers (OR 1.7). Hyper-caloric nutrition of the parents predicted the energy intake of the children in: mother-daughter (OR 7.5), mother-son (OR 3.0), and father-son (OR 2.8) pairs. Low mono-unsaturated fatty acid intake was significantly associated with a high LDL/HDL-C ratio (OR 3.4) and hypertriglyceridemia (OR 2.2) in fathers. Approximately 25% of parents and children reported at least two physical activities twice a week. The 23% of children who were passive smokers presented a far more adverse risk profile than children without exposure to second-hand smoke. Intergenerational lifestyle habits affect cardiovascular risk factors within biological families. As lifestyle habits are predictable, they may be used for implementation of family-based CVD prevention strategies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980001"}
{"pmid": "20980002", "title": "Elevated circulating soluble form of CD40 ligand in patients with cardiac syndrome X.", "content": "Elevated circulating soluble form of CD40 ligand in patients with cardiac syndrome X. The presence of effort induced angina, positive exercise stress test responses and angiographically normal coronary arteries defines cardiac syndrome X (CSX). Its pathogenesis, although mostly attributed to endothelial dysfunction and coronary microcirculation abnormalities, is incompletely understood. The soluble CD40 ligand (sCD40L) has multiple autocrine, paracrine and endocrine actions that may lead to endothelial dysfunction and atherothrombosis. We sought to investigate the relationship among sCD40L levels and ischemic burden in patients with CSX and whether sCD40L levels are increased in patients with CSX compared to control subjects. We assessed 30 prospectively enrolled patients with CSX and 28 apparently healthy subjects matched for coronary risk factors. All CSX patients and control subjects underwent myocardial perfusion scintigraphy. The summed difference score is taken to be an index of ischemic burden. This was classified as mildly, moderately and severely abnormal. White blood cells, sCD40L and C-reactive protein (CRP) concentrations were measured at peak exercise. At peak exercise, sCD40L levels were significantly greater in CSX patients than in the control group (P=0.008). Similarly, white blood cell count and CRP levels were higher in patients with CSX than in normal controls (P=0.02). After multivariable adjustment, sCD40L (P=0.03) was the only independent predictor of severe ischemic burden in CSX patients. The present study showed for the first time that sCD40L is associated with ischemic burden in patients with CSX. The potential role of this inflammatory molecule in the pathogenesis of CSX deserves investigation in future studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980002"}
{"pmid": "20979993", "title": "A non-linear morphometric feature selection approach for breast tumor contour from ultrasonic images.", "content": "A non-linear morphometric feature selection approach for breast tumor contour from ultrasonic images. Ultrasound breast images have been used to improve diagnostics and decrease the number of unneeded biopsies. Malignant breast tumors tend to present irregular and blurred contours while benign ones are usually round, smooth and well-defined. Accordingly, investigating the tumor contour may help in establishing diagnosis. Herein, Mutual Information and Linear Discriminant Analysis were implemented to rank morphometric features in discriminating breast tumors in ultrasound images. Seven features were extracted from Convex Polygon and the Normalized Radial Length techniques. By applying a Mutual Information based approach, it was possible to identity features with possibly non-linear contributions to the outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20979993"}
{"pmid": "20980003", "title": "Selective role of sterol regulatory element binding protein isoforms in aggregated LDL-induced vascular low density lipoprotein receptor-related protein-1 expression.", "content": "Selective role of sterol regulatory element binding protein isoforms in aggregated LDL-induced vascular low density lipoprotein receptor-related protein-1 expression. Low density lipoprotein receptor-related protein (LRP1) is upregulated in vascular smooth muscle cells by intravascular aggregated LDL (agLDL) - LDL trapped in the arterial intima and systemic LDL. LRP1 upregulation in hypercholesterolemic aortas is concomitant with SREBP downregulation. However, the specific role of SREBP isoforms in LRP1 transcription and LDL-induced LRP1 upregulation in human vascular smooth muscle cells (VSMC) is unknown. In the present study we report that specific silencing of either SREBP-1 or SREBP-2 enhanced LRP1 whereas overexpression of the active SREBP isoforms decreased LRP1 expression. Gel mobility shift and ChIP assays demonstrated that SREBP-1a, SREBP-1c and SREBP-2 were able to bind to three putative SRE sequences; SRE-A (-1042 to -1028), SRE-B (-115 to -101) and SRE-C (+226 to +234). ChIP assays demonstrated that agLDL (100μg/mL, 24h) significantly and specifically decreased SREBP-2 binding to the LRP1 promoter. Luciferase assays demonstrated that agLDL increased the transcriptional activity of A/B or A/C double mutants but failed to increase that of the double B/C mutant. Our results show that both SREBP-1 and SREBP-2 negatively modulated LRP1 transcription. Furthermore, agLDL exerted an upregulatory effect on LRP1 expression by decreasing SREBP-2 binding to LRP1 promoter. Two SRE-like sequences control the response of LRP1 to agLDL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980003"}
{"pmid": "20980004", "title": "Pole vault performance for anthropometric variability via a dynamical optimal control model.", "content": "Pole vault performance for anthropometric variability via a dynamical optimal control model. Optimal performance of a dynamical pole vault process was modeled as a constrained nonlinear optimization problem. That is, given a vaulter's anthropomorphic data and approach speed, the vaulter chose a specific take-off angle, pole stiffness and gripping height in order to yield the greatest jumping height compromised by feasible bar-crossing velocities. The optimization problem was solved by nesting a technique of searching an input-to-output mapping arising from the vaulting trajectory and a method of nonlinear sequential quadratic programming (SQP). It was suggested from the optimization results that the body's weight has an important influence on the vaulting performance beside the vaulter's height and approach speed; the less skilled vaulter should gradually adopt a longer pole to improve the performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980004"}
{"pmid": "20980005", "title": "Support vector machines for detecting age-related changes in running kinematics.", "content": "Support vector machines for detecting age-related changes in running kinematics. Age-related changes in running kinematics have been reported in the literature using classical inferential statistics. However, this approach has been hampered by the increased number of biomechanical gait variables reported and subsequently the lack of differences presented in these studies. Data mining techniques have been applied in recent biomedical studies to solve this problem using a more general approach. In the present work, we re-analyzed lower extremity running kinematic data of 17 young and 17 elderly male runners using the Support Vector Machine (SVM) classification approach. In total, 31 kinematic variables were extracted to train the classification algorithm and test the generalized performance. The results revealed different accuracy rates across three different kernel methods adopted in the classifier, with the linear kernel performing the best. A subsequent forward feature selection algorithm demonstrated that with only six features, the linear kernel SVM achieved 100% classification performance rate, showing that these features provided powerful combined information to distinguish age groups. The results of the present work demonstrate potential in applying this approach to improve knowledge about the age-related differences in running gait biomechanics and encourages the use of the SVM in other clinical contexts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980005"}
{"pmid": "20980007", "title": "Material properties of the cornea and sclera: a modelling approach to test experimental analysis.", "content": "Material properties of the cornea and sclera: a modelling approach to test experimental analysis. Material properties of cornea and sclera are important for maintaining the shape of the eye and the requisite surface curvatures for optics. They also need to withstand the forces of external and internal musculature and fluctuations in intraocular pressure (IOP). These properties are difficult to measure and variable results have been reported. A previously published experimental procedure, from which the material properties of the eyeball coats were obtained, has been modelled in this paper using Finite Element Analysis, in order to test the accuracy of the experiment. Material parameters were calculated from the model and the resulting relationships between stress and strain for the cornea and sclera compared to their experimentally obtained counterparts. The comparison between model and experiment was close for the sclera but more varied for the cornea. The pressure vessel model can be applied for measuring the material properties of the sclera but is less accurate for the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980007"}
{"pmid": "20980006", "title": "Hyperelastic properties of human meniscal attachments.", "content": "Hyperelastic properties of human meniscal attachments. Meniscal attachments are ligamentous tissues anchoring the menisci to the underlying subchondral bone. Currently little is known about the behavior of meniscal attachments, with only a few studies quantitatively documenting their properties. The objective of this study was to quantify and compare the tensile mechanical properties of human meniscal attachments in the transverse direction, curve fit experimental Cauchy stress-stretch data to evaluate the hyperelastic behavior, and couple these results with previously obtained longitudinal data to generate a more complete constitutive model. Meniscal attachment specimens were tested using a uniaxial tension test with the collagen fibers oriented perpendicular to the loading axis. Tests were run until failure and load-optical displacement data was recorded for each test. The medial posterior attachment was shown to have a significantly greater elastic modulus (6.42±0.78 MPa) and ultimate stress (1.73±0.32 MPa) when compared to the other three attachments. The Mooney-Rivlin material model was selected as the best fit for the transverse data and used in conjunction with the longitudinal data. A novel computational approach to determining the transition point between the toe and linear regions is presented for the hyperelastic stress-stretch curves. Results from piece-wise non-linear longitudinal curve fitting correlate well with previous linear elastic and SEM findings. These data can be used to advance the design of meniscal replacements and improve knee joint finite element models.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980006"}
{"pmid": "20980008", "title": "Prediction of applied forces in handrim wheelchair propulsion.", "content": "Prediction of applied forces in handrim wheelchair propulsion. Researchers of wheelchair propulsion have usually suggested that a wheelchair can be properly designed using anthropometrics to reduce high mechanical load and thus reduce pain and damage to joints. A model based on physiological features and biomechanical principles can be used to determine anthropometric relationships for wheelchair fitting. To improve the understanding of man-machine interaction and the mechanism through which propulsion performance been enhanced, this study develops and validates an energy model for wheelchair propulsion. Kinematic data obtained from ten able-bodied and ten wheelchair-dependent users during level propulsion at an average velocity of 1m/s were used as the input of a planar model with the criteria of increasing efficiency and reducing joint load. Results demonstrate that for both experienced and inexperienced users, predicted handrim contact forces agree with experimental data through an extensive range of the push. Significant deviations that were mostly observed in the early stage of the push phase might result from the lack of consideration of muscle dynamics and wrist joint biomechanics. The proposed model effectively verified the handrim contact force patterns during dynamic propulsion. Users do not aim to generate mechanically most effective forces to avoid high loadings on the joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980008"}
{"pmid": "20980009", "title": "Capillary zone electrophoresis of graphene oxide and chemically converted graphene.", "content": "Capillary zone electrophoresis of graphene oxide and chemically converted graphene. The preparation of processable graphene oxide colloids called chemically converted graphene (CCG) involves the following steps: oxidation of graphite to form graphite oxide; exfoliation of graphite oxide to form graphene oxide (GO); and reduction of GO to form CCG. In this work, the exfoliation and reduction steps were monitored by capillary zone electrophoresis (CZE). CZE was performed in fused silica capillaries with UV absorbance at 230 nm (GO) and 270 nm (CCG) using 250 μM tetrapropylammonium hydroxide (pH 10.4). The results indicate that almost complete exfoliation of graphite oxide (0.05 wt%) and higher recovery of CCG were obtained by sonication at 50% power for more than 15 h. CZE is considered a valuable tool for the fractionation and analysis of GO nanoparticles and, hence, for the control of different steps in preparation of CCG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980009"}
{"pmid": "20980010", "title": "Determination of nicotine and nicotine metabolites in urine by hydrophilic interaction chromatography-tandem mass spectrometry: Potential use of smokeless tobacco products by ice hockey players.", "content": "Determination of nicotine and nicotine metabolites in urine by hydrophilic interaction chromatography-tandem mass spectrometry: Potential use of smokeless tobacco products by ice hockey players. Consumption of nicotine in the form of smokeless tobacco (snus, snuff, chewing tobacco) or nicotine-containing medication (gum, patch) may benefit sport practice. Indeed, use of snus seems to be a growing trend and investigating nicotine consumption amongst professional athletes is of major interest to sport authorities. Thus, a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the detection and quantification of nicotine and its principal metabolites cotinine, trans-3-hydroxycotinine, nicotine-N'-oxide and cotinine-N-oxide in urine was developed. Sample preparation was performed by liquid-liquid extraction followed by hydrophilic interaction chromatography-tandem mass spectrometry (HILIC-MS/MS) operated in electrospray positive ionization (ESI) mode with selective reaction monitoring (SRM) data acquisition. The method was validated and calibration curves were linear over the selected concentration ranges of 10-10,000 ng/mL for nicotine, cotinine, trans-3-hydroxycotinine and 10-5000 ng/mL for nicotine-N'-oxide and cotinine-N-oxide, with calculated coefficients of determination (R(2)) greater than 0.95. The total extraction efficiency (%) was concentration dependent and ranged between 70.4 and 100.4%. The lower limit of quantification (LLOQ) for all analytes was 10 ng/mL. Repeatability and intermediate precision were ≤9.4 and ≤9.9%, respectively. In order to measure the prevalence of nicotine exposure during the 2009 Ice Hockey World Championships, 72 samples were collected and analyzed after the minimum of 3 months storage period and complete removal of identification means as required by the 2009 International Standards for Laboratories (ISL). Nicotine and/or metabolites were detected in every urine sample, while concentration measurements indicated an exposure within the last 3 days for eight specimens out of ten. Concentrations of nicotine, cotinine, trans-3-hydroxycotinine, nicotine-N'-oxide and cotinine-N-oxide were found to range between 11 and 19,750, 13 and 10,475, 10 and 8217, 11 and 3396, and 13 and 1640 ng/mL, respectively. When proposing conservative concentration limits for nicotine consumption prior and/or during the games (50 ng/mL for nicotine, cotinine and trans-3-hydroxycotinine and 25 ng/mL for nicotine-N'-oxide and cotinine-N-oxide), about half of the hockey players were qualified as consumers. These findings significantly support the likelihood of extensive smokeless nicotine consumption. However, since such conclusions can only be hypothesized, the potential use of smokeless tobacco as a doping agent in ice hockey requires further investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980010"}
{"pmid": "20980011", "title": "Towards porous polymer monoliths for the efficient, retention-independent performance in the isocratic separation of small molecules by means of nano-liquid chromatography.", "content": "Towards porous polymer monoliths for the efficient, retention-independent performance in the isocratic separation of small molecules by means of nano-liquid chromatography. We have investigated the free-radical copolymerization dynamics of styrene and divinylbenzene in the presence of micro- and macro-porogenic diluents in 100 μm I.D. sized molds under conditions of slow thermal initiation leading to (macro)porous poly(styrene-co-divinylbenzene) monolithic scaffolds. These specifically designed experiments allowed the quantitative determination of monomer specific conversion against polymerization time to derive the porous polymer scaffold composition at each desirable copolymerization stage after phase separation. This was carried out over a time scale of 3h up to 48 h polymerization time, enabling the efficient and repeatable termination of the polymerization reactions. In parallel, the porous and hydrodynamic properties of the derived monolithic columns were thoroughly studied in isocratic nano-LC mode for the reversed-phase separation of a homologous series of small retained molecules. At the optimized initiator concentration, polymerization temperature and time, the macroporous poly(styrene-co-divinylbenzene) monoliths show a permanent mesoporous pore space, which was readily observable by electron microscopy and indicated by nitrogen adsorption experiments. Under these conditions, we consistently find a polymer scaffold composition which suggests a high degree of cross-linking and thus minimum amount of gel porosity. These columns reveal a retention-insensitive plate height in the separation of small retained molecules which only slightly decreases at increased linear mobile phase velocity. As the polymerization progresses, a build-up of less-densely cross-linked material occurs, which is directly reflected in the observed consistent increase in retention and plate heights. This leads to a significant deterioration in overall isocratic separation performance. The decrease in performance is ascribed in particular to the increased mass transfer resistance governing the monoliths' performance over the whole linear chromatographic flow velocity range at polymerization times significantly higher than that of phase separation. The performance of the optimized monoliths only becomes limited by fluid dispersion due to the poorly structured macroporous pore space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980011"}
{"pmid": "20980012", "title": "Identification of amino-tadalafil and rimonabant in electronic cigarette products using high pressure liquid chromatography with diode array and tandem mass spectrometric detection.", "content": "Identification of amino-tadalafil and rimonabant in electronic cigarette products using high pressure liquid chromatography with diode array and tandem mass spectrometric detection. A high-pressure liquid chromatography-diode array detection and multi-mode ionization tandem mass spectrometry (HPLC-DAD-MMI-MS/MS) method was used to identify amino-tadalafil and rimonabant in electronic cigarette (e-cigarette) cartridges. Amino-tadalafil is a drug analogue of the commercially approved Cialis™ (i.e. tadalafil). Rimonabant is a drug that was, at one time, approved for weight loss in Europe (although approval has been retracted), but not in the United States. In addition, poor quality control over the e-cigarette products analyzed here is shown by the presence of nicotine in products labeled as containing no nicotine or by the presence of significant amounts of rimonabant oxidative degradant in e-cigarette products containing rimonabant. Identification was accomplished by comparing the retention time of relevant peaks in the sample with those of standard compounds, in addition to comparison of the UV spectra, mass spectra and/or product ion mass spectra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980012"}
{"pmid": "20980013", "title": "In-tube solid-phase microextraction based on hybrid silica monolith coupled to liquid chromatography-mass spectrometry for automated analysis of ten antidepressants in human urine and plasma.", "content": "In-tube solid-phase microextraction based on hybrid silica monolith coupled to liquid chromatography-mass spectrometry for automated analysis of ten antidepressants in human urine and plasma. A rapid, sensitive and automated in-tube solid-phase microextraction-liquid chromatography-mass spectrometry (in-tube SPME/LC-MS) method was developed for the analysis of ten antidepressants in urine and plasma. A hybrid organic-inorganic silica monolith with cyanoethyl functional groups was prepared and used as a sorbent for in-tube SPME. Integration of the sample extraction, LC separation and MS detection into a single system permitted direct injection of the diluted urine or plasma after filtration. Under the optimized conditions, good extraction efficiencies for the targets were obtained with no matrix interference in the subsequent LC-MS. Automation of the sampling, extraction and separation procedures was realized under the control of a program in this study. The total process time was 30 min and only 30 μL of urine or plasma was required in one analysis cycle. Good linearities were obtained for ten antidepressants with the correlation coefficients (R) above 0.9933. The limits of detection (S/N=3) for ten antidepressants were found to be 0.06-2.84 ng/mL in urine and 0.07-2.95 ng/mL in plasma. The recoveries of antidepressants spiked in urine and plasma were from 75.2% to 113.0%, with relative standard deviations less than 16.5%. The developed method was successfully used to analyze urine sample from ageing patients undergoing therapy with antidepressants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980013"}
{"pmid": "20980014", "title": "Flux decline during cross flow membrane filtration of electrolytic solution in presence of charged nano-colloids: a simple electrokinetic model.", "content": "Flux decline during cross flow membrane filtration of electrolytic solution in presence of charged nano-colloids: a simple electrokinetic model. An electrokinetic transport based approach for quantification of reversible flux decline due to the concentration polarization of an electrolyte solution in presence of charged colloids is presented. The model envisions the electrolyte transport across a charged cake or gel layer as transport of ions through charged cylindrical capillaries. This model is coupled with the standard theory of concentration polarization during cross flow membrane filtration. The analysis is carried out entirely in terms of generalized, non-dimensional variables. A dimensionless group termed as the scaled gel layer resistance evolves from the analysis, which accounts for the electrical properties of the charged nano-colloids and the electrolyte solution. A parametric study is performed to elucidate the coupled influence of mass transfer, membrane resistance, gel resistance, and electrical properties of the gel-electrolyte polarized layer. The effects of these parameters are examined on the filtration performance through the model equations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980014"}
{"pmid": "20980015", "title": "Solid state white light emitting systems based on CeF3: RE3+ nanoparticles and their composites with polymers.", "content": "Solid state white light emitting systems based on CeF3: RE3+ nanoparticles and their composites with polymers. A series of doped CeF(3): RE(3+) (RE(3+): Tb(3+), Eu(3+) and Dy(3+)) nanoparticles were synthesized, with the aim of obtaining a white light emitting composition, by a simple polyol route at 160°C and characterized by X-ray diffraction (XRD), high resolution transmission electron microscopy (HR-TEM), Fourier transform infrared spectroscopy (FT-IR) and photoluminescence. Uniformly distributed and highly water-dispersible rectangular nanoparticles (length ~15-20 nm, breadth ~5-10 nm) were obtained. The steady state and time resolved luminescence studies confirmed efficient energy transfer from the host to activator ions. Lifetime studies revealed that optimum luminescence is observed for 2.5 mol% Dy(3+) and 7.5 mol% Tb(3+). The energy transfer efficiencies (Ce(3+) to activators) were found to be 89% for CeF(3): Tb(3+) (7.5 mol%) nanoparticles and 60% for CeF(3): Dy(3+) (2.5 mol%) nanoparticles. Different concentrations of Tb(3+), Eu(3+) and Dy(3+) were doped to achieve a white light emitting phosphor for UV-based LEDs (light emitting diodes). Finally CeF(3), triply doped with 2.0 mol%Tb(3+), 4.5 mol% Eu(3+) and 3.5 mol% Dy(3+), was found to have impressive chromaticity co-ordinates, close to broad day light. The colloidal solutions of doped CeF(3) nanoparticles emitted bright green (Tb(3+)), blue (Dy(3+)) and white (triply doped) luminescence upon host excitation. Composites of poly methyl methacrylate (PMMA) and poly vinyl alcohol (PVA) were made with CeF(3): 5.0 mol%Tb(3+), CeF(3): 5.0 mol% Dy(3+) and triply doped white light emitting composition. The CeF(3)/PMMA (PVA) nanocomposite films, so obtained, are highly transparent (in the visible spectral range) and exhibit strong photoluminescence upon UV excitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980015"}
{"pmid": "20980016", "title": "Adsorption of CO2 and CH4 on a magnesium-based metal organic framework.", "content": "Adsorption of CO2 and CH4 on a magnesium-based metal organic framework. A magnesium-based metal organic framework (MOF), also known as Mg-MOF-74, was successfully synthesized, characterized, and evaluated for adsorption equilibria and kinetics of CO(2) and CH(4). The Mg-MOF-74 crystals were characterized with scanning electron microscopy for crystal structure, powder X-ray diffraction for phase structure, and nitrogen adsorption for pore textural properties. Adsorption equilibrium and kinetics of CO(2) and CH(4) on the Mg-MOF-74 adsorbent were measured in a volumetric adsorption unit at 278, 298, and 318 K and pressures up to 1 bar. It was found that the Mg-MOF-74 adsorbent prepared in this work has a median pore width of 10.2 Å, a BET specific surface area of 1174 m(2)/g, CO(2) and CH(4) adsorption capacities of 8.61 mmol g(-1) (37.8 wt.%) and 1.05 mmol g(-1) (1.7 wt.%), respectively, at 298 K and 1 bar. Both CO(2) and CH(4) adsorption capacities are significantly higher than those of zeolite 13X under similar conditions. The pressure-dependent equilibrium selectivity of CO(2) over CH(4) (q(CO2)/q(CH4)) in the Mg-MOF-74 adsorbent showed a trend similar to that of zeolite 13X and the intrinsic selectivity of Mg-MOF-74 at zero adsorption loading is 283 at 298 K. The initial heats of adsorption of CO(2) and CH(4) on the Mg-MOF-74 adsorbent were found to be 73.0 and 18.5 kJ mol(-1), respectively. The adsorption kinetic measurements suggest that the diffusivities of CO(2) and CH(4) on Mg-MOF-74 were comparable to those on zeolite 13X. CH(4) showed relatively faster adsorption kinetics than CO(2) in both adsorbents. The diffusion time constants of CO(2) and CH(4) in the Mg-MOF-74 adsorbent at 298 K were estimated to be 8.11 × 10(-3) and 4.05 × 10(-2) s(-1), respectively, showing a modest kinetic selectivity of about 5 for the separation CH(4) from CO(2).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980016"}
{"pmid": "20980017", "title": "Reversible organogels triggered by dynamic K+ binding and release.", "content": "Reversible organogels triggered by dynamic K+ binding and release. In this study, a new lipophilic guanosine derivative was synthesized as an organogelator. The self-aggregation behavior of this organogelator was investigated by NMR, XRD and AFM. In solution, the lipophilic guanosine derivative can form a stable ribbon-like structure through NH(1)-N(7) and NH(2)-O(6) hydrogen bonds. However, gelation would occur in some aprotic solvents after the concentration reached a definite value. More interesting, the ribbon-like structure was able to change to G-quartets in the presence of K(+), which led to the transformation from a gel to a sol. Upon the addition of the cryptand [2.2.2], which can efficiently complex with K(+), G-quartets reverted to the original ribbon-like structure and the gel recovered. Subsequently, upon the addition of acids, K(+) was released from the cryptate with the transformation of gel-to-sol simultaneously. Finally, upon the addition of bases which deprotonated [H(+) ⊂ 2.2.2], the liberated cryptand [2.2.2] recaptured K(+) and the gel was regenerated again. This process of interconversion between G-ribbon 1(n) and octamer 1(8)·K(+) was well monitored by circular dichroism spectra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980017"}
{"pmid": "20980018", "title": "Copper hydroxide nano and microcrystal: facile synthesis, shape evolution and their catalytic properties.", "content": "Copper hydroxide nano and microcrystal: facile synthesis, shape evolution and their catalytic properties. In this paper, the morphology of copper hydroxide nano/microcrystals is finely controlled by adjusting the concentration of surfactant and NH(4)Cl as well as the reaction temperature, to provide plates, belts, wires, rods and urchin-like spheres, among others. A tree-type multiple head surfactant, bis (amidoethyl-carbamoylethyl) octadecylamine (C18N3), was used to prepare the copper hydroxide nano/microcrystals and it acted as a face-selective additive in the reaction system. The morphology of the Cu(OH)(2) microcrystals could be transformed from elliptical plates into truncated square plates as the NH(4)Cl concentration was increased. The results showed that the Cu(OH)(2) crystals were better than the amorphous type of Cu(OH)(2) in catalyzing the oxidation of resorcinol with H(2)O(2). Additionally, an investigation of the formation process of the nano/microcrystals was performed, which we believe is valuable for a precise understanding of the formation and fabrication of other metal hydroxides and metal oxides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980018"}
{"pmid": "20980019", "title": "Phonemes matter: the role of phoneme-level awareness in emergent Chinese readers.", "content": "Phonemes matter: the role of phoneme-level awareness in emergent Chinese readers. The importance of phonological awareness for learning to read may depend on the linguistic properties of a language. This study provides a careful examination of this language-specific theory by exploring the role of phoneme-level awareness in Mandarin Chinese, a language with an orthography that, at its surface, appears to require little phoneme-level insight. A sample of 71 monolingual Mandarin-speaking children completed a phonological elision task and a measure of single-character reading. In this sample, 4- and 5-year-old preschoolers were unable to complete phoneme-level deletions, whereas 6- to 8-year-old first graders were able to complete initial, final, and medial phoneme-level deletions. In this older group, performance on phoneme deletions was significantly related to reading ability even after controlling for syllable- and onset/rime-level awareness, vocabulary, and Pinyin knowledge. We believe that these results reopen the question of the role of phonological awareness in reading in Chinese and, more generally, the nature of the mechanisms underlying this relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980019"}
{"pmid": "20980020", "title": "Preschoolers' total daily screen time at home and by type of child care.", "content": "Preschoolers' total daily screen time at home and by type of child care. To assess preschoolers' cumulative daily screen time, measure the contributions of the home and the child care setting to this total, and characterize children that are most at risk for excessive screen time. We used data from the Early Childhood Longitudinal Study-Birth Cohort, to calculate daily screen time based on reports by preschooler's parents and care providers. The sample size of 8950 represented approximately 4 million children. By preschool age, >80% of children were in some child care. On average, children in this study were exposed to 4.1 hours of screen time daily, including 3.6 hours at home and 0.4 hours in child care. Children in centers had the lowest screen time (3.2 hours) compared with children in parental care only (4.4 hours), home-based care (5.5 hours), and Head Start (4.2 hours). Even when adjusted for relevant covariates, these differences remained significant (P < .001). Preschoolers' cumulative screen time exceeds recommendations and most previous estimates. Pediatric clinicians are uniquely positioned to encourage families to discuss screen time with their children's caregivers and to advocate for high quality child care. Efforts to decrease screen time in homes and home-based child care settings are needed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980020"}
{"pmid": "20980021", "title": "Seasonal severity of depressive symptoms as a predictor of health service use in a community-based sample.", "content": "Seasonal severity of depressive symptoms as a predictor of health service use in a community-based sample. To determine whether severity of seasonal depressive symptoms is an independent predictor of depression-specific health service use. Cross-sectional telephone survey evaluating mood-related symptom changes across seasons using a structured interview based on the World Mental Health Composite International Diagnostic Interview, in a community sample representative of the province of Ontario, Canada (N = 1605). This study focuses on the 625 individuals (out of a total of 1605 interviewed) who screened positive for lifetime depressive symptoms. Severity of seasonal symptoms of depression (or \"seasonality\") was measured using the Seasonal Depression Severity (SDS) score (range 0-36). The primary outcome was lifetime depression-specific use of health services from a physician (family physician or psychiatrist). Lifetime psychotropic medication use, use of health services from a non-physician therapist, and psychiatric hospitalization were secondary outcomes. Other important variables that are known to predict depression-specific health service use were considered in multivariable analysis. In our sample of individuals with depressive symptoms, those who had used physician health services had higher SDS scores than non-users (11.5 (SD 7.2) vs. 9.7 (SD 6.4), t(616) = 3.182, P = 0.001). In multivariable analysis, SDS score was independently associated with depression-specific health service use by a physician (OR = 1.04, 95% CI 1.01-1.07, p = 0.004). The relationship between seasonality and use of psychotropic medication use was similar (OR = 1.04, 95% CI 1.01-1.07, p = 0.007). Seasonality was independently associated with depression-specific health service use for individuals with depressive symptoms. The results imply that greater seasonality may independently reflect increased severity and need for treatment of depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980021"}
{"pmid": "20980032", "title": "Triterpene glycosides from the aerial parts of Larrea tridentata.", "content": "Triterpene glycosides from the aerial parts of Larrea tridentata. Chemical study of the aerial parts of Larrea tridentata (Zygophyllaceae) resulted in the isolation of 25 triterpene glycosides, 13 of which were previously unknown. Their structures were determined on the basis of comprehensive spectroscopic analyses, including 2D NMR spectroscopy, and hydrolytic cleavage followed by chromatographic and spectroscopic analyses. This is the first systematic phytochemical study of L. tridentata with attention paid to its triterpene glycoside constituents. The isolated compounds were evaluated for their cytotoxic activity against HL-60 human promyelocytic leukemia cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980032"}
{"pmid": "20980033", "title": "Virulence genes and plasmid profiles in Rhodococcus equi isolates from domestic pigs and wild boars (Sus scrofa) in Brazil.", "content": "Virulence genes and plasmid profiles in Rhodococcus equi isolates from domestic pigs and wild boars (Sus scrofa) in Brazil. The virulence genes and plasmid profiles of 23 Rhodococcus equi isolates from 258 lymph nodes from domestic pigs (129 nodes with lesions and 129 without lesions) and 120 lymph nodes from slaughtered wild boars (60 nodes with lesions and 60 without) were characterized. R. equi was obtained from 19 lymph nodes of domestic pigs, 17 with, and two without lesions, and from four lymph nodes with lesions, from wild boars. The 23 isolates were tested for the presence of vapA and vapB genes, responsible for the 15-17 and 20 kDa virulence-associated proteins, respectively, by PCR in order to characterize as virulent (VapA), intermediately virulent (VapB) and avirulent. Plasmid DNAs were isolated and analyzed by digestion with restriction endonucleases to estimate size and compare their polymorphisms. Of the 19 domestic pigs strains, seven (36.8%) were avirulent and 12 (63.2%) were intermediately virulent, with the intermediately virulent isolates being plasmid types 8 (8 isolates), 10 (2 isolates), 1 (1 isolate) and 29 (1 isolate). The plasmid type of four strains isolated from wild boars was also intermediately virulent type 8. None of the domestic pigs and wild boar isolates showed the vapA gene. These findings demonstrate a high occurrence of plasmid type 8 in isolates from pigs and wild boars, and the similarity of plasmid types in the domestic pigs, wild boars and human isolates in Brazil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980033"}
{"pmid": "20980035", "title": "Obesity induced changes to plasma adiponectin concentration and cholesterol lipoprotein composition profile in cats.", "content": "Obesity induced changes to plasma adiponectin concentration and cholesterol lipoprotein composition profile in cats. Feline obesity generally results in aberrations to plasma metabolite levels, such as lipid concentrations and lipoprotein composition. This study sought to investigate the resultant effect of obesity on cholesterol lipoprotein composition and circulating adiponectin concentrations in cats. Plasma glucose, lipids (triglyceride, cholesterol and free fatty acid), insulin and adiponectin concentrations, and cholesterol lipoprotein composition were measured and compared between body condition score (BCS) determined normal healthy control and obese cats. Although the obese group demonstrated higher levels of plasma cholesterol, glucose, and triglycerides, as compared to healthy controls, the difference was insignificant thus indicating that the BCS determined obese cats may have been overweight and not morbidly obese. Plasma insulin levels were significantly higher (25-30%) versus healthy control animals thereby possibly hinting at the ensuing emergence of obesity induced insulin resistance. However, the BCS determined obese cat demonstrated a significant reduction (p<0.05) in plasma adiponectin concentration and a significant increase (p<0.05) in LDL-cholesterol % as compared to age matched healthy control animals. This would indicate that changes in plasma adiponectin concentration and cholesterol lipoprotein composition may be good early indicators of obesity in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980035"}
{"pmid": "20980034", "title": "Efficacy of anthelmintic properties of medicinal plant extracts against Haemonchus contortus.", "content": "Efficacy of anthelmintic properties of medicinal plant extracts against Haemonchus contortus. The development of anthelmintic resistance has made the search for alternatives to control gastrointestinal nematodes of small ruminants imperative. Among these alternatives are several medicinal plants traditionally used as anthelmintics. This present work evaluated the efficacy of ethyl acetate, acetone, and methanol dried leaf and seed extracts of five medicinal plants were tested in vitro ovicidal and larvicidal activities on Haemonchus contortus. The in vitro assay was based on egg hatch assay (EHA) and larval development assay (LDA), all plant extracts were evaluated at five concentrations 50, 25, 12.5, 6.25 and 3.13 mg/ml. The leaf and seed ethyl acetate, acetone and methanol of Annona squamosa, Eclipta prostrata, Solanum torvum, Terminalia chebula, and Catharanthus roseus extracts were showed complete inhibition (100%) at the maximum concentration tested (50 mg/ml). The overall findings of the present study have shown that our experimental plant extracts contain possible anthelmintic compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980034"}
{"pmid": "20980036", "title": "Factors affecting porcine sperm mediated gene transfer.", "content": "Factors affecting porcine sperm mediated gene transfer. \"Sperm mediated gene transfer\" (SMGT) is based on the ability of sperm cells to bind exogenous DNA. The main objective of this study was to improve the production of transgenic pigs by SMGT. Taking into account that there is a lack of repeatability in studies of SMGT and that the mechanism of binding and internalization of exogenous DNA is a question that has not been solved, different factors involved in the production of transgenic animals by SMGT method were evaluated. Here we set out to: (1) evaluate the sperm capacity to bind exogenous DNA after DMSO treatment; (2) determine the location of the transgene-spermatozoa interaction; and (3) evaluate the efficiency of production of transgenic piglets by deep intrauterine artificial insemination (AI) with sperm incubated with DNA. The percentage of DNA binding was higher than 30% after 2h of co-culture, but it was not affected by sperm treatment with DMSO (0.3% or 3%). The integrity of the sperm plasma membrane plays a critical role in DNA interaction, and altered plasma membranes facilitate interactions with exogenous DNA. DNA bound mainly to spermatozoa with reduced viability. DNA molecules were found to be mainly associated to the post-acrosomal region (61.9%). After deep intrauterine AI a total of 29 piglets were obtained, but none of them integrated the transgene. In conclusion, although it has been confirmed that DNA can associate with boar spermatozoa, the efficiency of producing transgenic pigs by AI was not confirmed by the present experiments, mainly due to a reduced DNA binding to functional spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980036"}
{"pmid": "20980037", "title": "In vivo efficacy of tamarind (Tamarindus indica) fruit extract on experimental fluoride exposure in rats.", "content": "In vivo efficacy of tamarind (Tamarindus indica) fruit extract on experimental fluoride exposure in rats. The study was undertaken to determine the efficacy of hydro-methanolic (1:1) extract of tamarind (Tamarindus indica L.) fruit pulp in removing body fluoride burden. Thirty rats were divided into five groups. Keeping no fluoride group as the control, rats of no treatment, low dose, middle dose and high dose groups received sodium fluoride orally at the rate of 200mg per kg body weight daily for 14 weeks. Rats of low dose, middle dose and high dose group simultaneously received tamarind fruit pulp extract at three doses, viz. 25 (low), 50 (medium) and 100mg (high) per kg body weight orally, respectively. Fluoride concentration in blood, urine and long bone of experimental rats was monitored to assess the efficacy of the extract. Mean serum fluoride concentration in fluoride exposed rats was 0.145 ± 0.009 and 0.783 ± 0.042 μg/ml on days 0 and 98. In comparison, fluoride concentrations in tamarind treated rats were 0.179 ± 0.021 and 0.633 ± 0.015; 0.179 ± 0.021 and 0.502 ± 0.025 and 0.176 ± 0.021 and 0.498 ± 0.030 μg/ml in low, medium and high dose groups, respectively on day 0 and day 98 of the experiment. There was a significant (p ≤ 0.01) increase in urinary fluoride excretion from day 28 onwards. The mean fluoride concentration in long bones of treated rats was significantly lower than the values recorded in fluoride exposed rats. These findings suggest that concomitant use of tamarind fruit pulp extract can reduce fluoride concentration in blood and bone and enhanced urinary excretion, indicating the ameliorative potential of fruits of tamarind in fluoride toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980037"}
{"pmid": "20980038", "title": "Low-cost struvite production using source-separated urine in Nepal.", "content": "Low-cost struvite production using source-separated urine in Nepal. This research investigated the possibility of transferring phosphorus from human urine into a concentrated form that can be used as fertilizer in agriculture. The community of Siddhipur in Nepal was chosen as a research site, because there is a strong presence and acceptance of the urine-diverting dry toilets needed to collect urine separately at the source. Furthermore, because the mainly agricultural country is landlocked and depends on expensive, imported fertilizers, the need for nutrient security is high. We found that struvite (MgNH(4)PO(4)·6H(2)O) precipitation from urine is an efficient and simple approach to produce a granulated phosphorus fertilizer. Bittern, a waste stream from salt production, is a practical magnesium source for struvite production, but it has to be imported from India. Calculations show that magnesium oxide produced from locally available magnesite would be a cheaper magnesium source. A reactor with an external filtration system was capable of removing over 90% of phosphorus with a low magnesium dosage (1.1 mol Mg mol P), with coarse nylon filters (pore width up to 160±50 μm) and with only one hour total treatment time. A second reactor setup based on sedimentation only achieved 50% phosphate removal, even when flocculants were added. Given the current fertilizer prices, high volumes of urine must be processed, if struvite recovery should be financially sustainable. Therefore, it is important to optimize the process. Our calculations showed that collecting the struvite and calcium phosphate precipitated spontaneously due to urea hydrolysis could increase the overall phosphate recovery by at least 40%. The magnesium dosage can be optimized by estimating the phosphate concentration by measuring electrical conductivity. An important source of additional revenue could be the effluent of the struvite reactor. Further research should be aimed at finding methods and technologies to recover the nutrients from the effluent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980038"}
{"pmid": "20980039", "title": "The influence of gill and liver metabolism on the predicted bioconcentration of three pharmaceuticals in fish.", "content": "The influence of gill and liver metabolism on the predicted bioconcentration of three pharmaceuticals in fish. The potential for xenobiotic compounds to bioconcentrate is typically expressed through the bioconcentration factor (BCF), which has gained increased regulatory significance over the past decade. Due to the expense of in vivo bioconcentration studies and the growing regulatory need to assess bioconcentration potential, BCF is often calculated via single-compartment models, using K(OW) as the primary input. Recent efforts to refine BCF models have focused on physiological factors, including the ability of the organism to eliminate the compound through metabolic transformation. This study looks at the ability of in vitro biotransformation assays using S9 fractions to provide an indication of metabolic potential. Given the importance of the fish gill and liver in metabolic transformation, the metabolic loss of ibuprofen, norethindrone and propranolol was measured using rainbow trout (Oncorhynchus mykiss) and channel catfish (Ictalurus punctatus) gill and liver S9 fractions. Metabolic transformation rates (k(M)) were calculated and integrated into a refined BCF model. A significant difference was noted between BCF solely based on K(OW) and BCF including k(M). These studies indicate that the inclusion of k(M) in BCF models can bring predicted bioconcentration estimates closer to in vivo values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980039"}
{"pmid": "20980041", "title": "Interaction of engineered nanoparticles with various components of the environment and possible strategies for their risk assessment.", "content": "Interaction of engineered nanoparticles with various components of the environment and possible strategies for their risk assessment. Nanoparticles are the materials with at least two dimensions between 1 and 100 nm. Mostly these nanoparticles are natural products but their tremendous commercial use has boosted the artificial synthesis of these particles (engineered nanoparticles). Accelerated production and use of these engineered nanoparticles may cause their release in the environment and facilitate the frequent interactions with biotic and abiotic components of the ecosystems. Despite remarkable commercial benefits, their presence in the nature may cause hazardous biological effects. Therefore, detail understanding of their sources, release interaction with environment, and possible risk assessment would provide a basis for safer use of engineered nanoparticles with minimal or no hazardous impact on environment. Keeping all these points in mind the present review provides updated information on various aspects, e.g. sources, different types, synthesis, interaction with environment, possible strategies for risk management of engineered nanoparticles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980041"}
{"pmid": "20980040", "title": "Alkylphenol oxidation with a laccase from a white-rot fungus: effects of culture induction and of ABTS used as a mediator.", "content": "Alkylphenol oxidation with a laccase from a white-rot fungus: effects of culture induction and of ABTS used as a mediator. We investigated the potential of the laccase from the white-rot fungus Marasmius quercophilus to transform certain alkylphenols (p-nonylphenol, p-octylphenol and p-t-octylphenol). We tested the reactivity of this enzyme under different conditions: in liquid cultures and using the partially purified laccase with and without 2,2'-azino-bis-3-ehtylbenzothiazoline-6-sulfonicacid (ABTS) as a mediator. The percentage of p-t-octylphenol disappearance in liquid cultures was 69.0 ± 1.5% and 81 ± 5% after a 8-d or 15-d incubation, respectively, with p-nonylphenol, these percentages were 62 ± 4% and 91 ± 6% and with p-octylphenol 37 ± 3% and 65 ± 1% after a 15-d and a 21-d incubations, respectively. Induced pre-cultures were also used to inoculate the liquid cultures to enhance p-octylphenol transformation: the percentages of disappearance were 91.0 ± 0.5% and 97 ± 1% after a 8-d and a 15-d incubation, respectively. Mass spectrometry analysis showed that the products of oxidation of p-octylphenol were dimers with a mass of 411 m/z. Furthermore, we identified a purple compound (m/z 476) formed when ABTS was added to the reaction medium with the purified laccase. This result confirms that, in complex environments such as soils or litters where many molecules can interact with the enzyme substrate or the product of oxidation, laccase activities and those of other phenoloxidases should not be measured with ABTS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980040"}
{"pmid": "20980042", "title": "Secretion profiles of fungi as potential tools for metal ecotoxicity assessment: a study of enzymatic system in Trametes versicolor.", "content": "Secretion profiles of fungi as potential tools for metal ecotoxicity assessment: a study of enzymatic system in Trametes versicolor. The relationship between the expression of extracellular enzymatic system and a metal stress is scarce in fungi, hence limiting the possible use of secretion profiles as tools for metal ecotoxicity assessment. In the present study, we investigated the effect of Zn, Cu, Pb and Cd, tested alone or in equimolar cocktail, on the secretion profiles at enzymatic and protein levels in Trametesversicolor. For that purpose, extracellular hydrolases (acid phosphatase, β-glucosidase, β-galactosidase and N-acetyl-β-glucosaminidase) and ligninolytic oxidases (laccase, Mn-peroxidase) were monitored in liquid cultures. Fungal secretome was analyzed by electrophoresis and laccase secretion was characterized by western-blot and mass spectrometry analyses. Our results showed that all hydrolase activities were inhibited by the metals tested alone or in cocktail, whereas oxidase activities were specifically stimulated by Cu, Cd and metal cocktail. At protein level, metal exposure modified the electrophoretic profiles of fungal secretome and affected the diversity of secreted proteins. Two laccase isoenzymes, LacA and LacB, identified by mass spectrometry were differentially glycosylated according to the metal exposure. The amount of secreted LacA and LacB was strongly correlated with the stimulation of laccase activity by Cu, Cd and metal cocktail. These modifications of extracellular enzymatic system suggest that fungal oxidases could be used as biomarkers of metal exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980042"}
{"pmid": "20980043", "title": "Effects of selected pharmaceutically active compounds on the ammonia oxidizing bacterium Nitrosomonas europaea.", "content": "Effects of selected pharmaceutically active compounds on the ammonia oxidizing bacterium Nitrosomonas europaea. Pharmaceutically active compounds (PhACs) are commonly found in wastewater influent. However, little research has focused on determining their impact on fundamental processes in wastewater treatment such as nitrogen removal. In this study, focus was placed on 4 commonly occurring PhACs (ketoprofen, naproxen, carbamazepine and gemfibrozil). Their effect was ascertained in the ammonia oxidizing bacterium (AOB), Nitrosomonas europaea in terms of membrane integrity and nitrite production. These PhACs were shown to inhibit nitrite production at concentrations of 1 and 10 μM while no effect was observed at 0.1 μM. The maximum observed nitrification inhibition was 25%, 29%, 22% and 26% for ketoprofen, naproxen, carbamazepine and gemfibrozil, respectively. A decrease in the live/dead ratio ranging from 10% to 16% suggests that these PhACs affect membrane integrity in N.europaea. The difference in nitrite production between PhACs treated cells and non PhAC treated controls was still significant following washing suggesting that inhibition is irreversible. Finally, nitrite production when adjusted to the live fraction of cells was also found to decrease suggesting that PhACs inhibited the activity of surviving cells. These results suggest that the presence of PhACs may affect AOB activity and may impact nitrogen removal, a key function in wastewater treatment. Follow up studies with additional AOB and in mixed culture are needed to further confirm these results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980043"}
{"pmid": "20980044", "title": "Levels and congener profiles of PCBs and PCDD/Fs in blue shark (Prionace glauca) liver from the South-Eastern Mediterranean Sea (Italy).", "content": "Levels and congener profiles of PCBs and PCDD/Fs in blue shark (Prionace glauca) liver from the South-Eastern Mediterranean Sea (Italy). Liver of blue shark (Prionace glauca) specimens from the South-Eastern Mediterranean Sea were analyzed for the presence of polychlorinated biphenyls (PCBs), including coplanar congeners, polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). PCBs were the dominant chemicals, followed by PCDFs and PCDDs. The pattern of PCB congener concentrations in the hepatic tissue was dominated by higher chlorinated compounds. The specific profile of toxic PCDD/F congeners was characterized mainly by 2,3,7,8-TCDF and 2,3,7,8-TCDD, followed by 1,2,3,6,7,8-HxCDD and 2,3,4,6,7,8-HxCDF. The total 2,3,7,8-TCDD toxic equivalent (TEQs) was 149 pg g⁻¹ lipid wt. The profile of TEQ shows that PCDDs present the greatest risk to this species contributing to total toxicity with a percentage approximately of 60%, while the contribution of PCDFs and DL-PCBs is almost the same being 22.4% and 21.6%, respectively. Further investigations are urgently needed to characterize the PCDD/Fs contamination levels not only in elasmobranch fish but in all Mediterranean marine biota.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980044"}
{"pmid": "20980045", "title": "Removal of dissolved estrogen in sewage effluents by β-cyclodextrin polymer.", "content": "Removal of dissolved estrogen in sewage effluents by β-cyclodextrin polymer. Substances with estrogenic activity are found in effluents of municipal sewage plants and dairy farms. These effluents have the potential to induce feminization in male fish. In this study, cyclodextrin polymers (CDPs) that are insoluble in both polar and non-polar solvents were selected for the removal of dissolved estrogens in the effluent of a municipal sewage plant. The removal capacity of CDPs was high in the order of β-CDP≥γ-CDP≫α-CDP. The mechanism for adsorption of estrogens to β-CDP was not only due to a host-guest interaction as molecular recognition by β-cyclodextrin (β-CD), but also due to adsorption by the polymer matrix. β-CDP of 0.2% (w/v) removed 17β-estradiol (E2) of about 70% from 10(-11)mol/L, and more than 90% from ≥10(-10)mol/L. The removal ratios of E2 in the presence of cholesterols, which are contained at higher concentrations than estrogens in sewage effluents and are adsorptive competitor for β-CDP, were about 85% at a cholesterol/E2 molar ratio of 100 and >90% at molar ratios of 0.1, 1, and 10. The effluent from a municipal sewage plant had estrogenic activity corresponding to 5.5×10(-11)molE2/L by yeast two-hybrid assay. The estrogens in the effluent were also removed >90% by the β-CDP treatment. Therefore, β-CDP is able to remove dissolved estrogens over a wide range of concentrations in the presence of various contaminants such as wastewaters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980045"}
{"pmid": "20980046", "title": "Novel robotic da Vinci instruments for laparoendoscopic single-site surgery.", "content": "Novel robotic da Vinci instruments for laparoendoscopic single-site surgery. To describe novel robotic laparoendoscopic single-site surgery (R-LESS) instruments, and present the initial laboratory experience in urology. The VeSPA surgical instruments (Intuitive Surgical, Sunnyvale, CA) were designed to be used with the DaVinci Si surgical system. A multichannel port and curved cannulae were inserted through a single 3.5-cm umbilical incision. The port allowed 1 scope, 2 robotic instruments, and a 5- to 12-mm assistant instrument. Four pyeloplasties (right 2, left 2), 4 partial nephrectomies (right 2, left 2), and 8 nephrectomies (right 4, left 4) were performed in 4 female farm pigs (mean weight, 34.5 kg). Technical feasibility and efficiency were assessed in addition to perioperative outcomes. All 16 R-LESS procedures were performed successfully without the addition of laparoscopic ports or open conversion. Mean total operative time was 110 minutes (range, 82-127), and mean blood loss was 20 mL (range, 10-100). Mean warm ischemia time for partial nephrectomy was 14.8 minutes (range, 12-20). There were no intraoperative complications. No robotic system failures occurred, and robotic instrument clashing was found to be minimal. One needle driver malfunctioned and assistant movement was limited. R-LESS kidney surgery using the VeSPA instruments is feasible and efficient in the porcine model. The system offers a wide range of motion, instrument and scope stability, improved ergonomics, and minimal instrument clashing. Although preliminary experience is encouraging, further refinements are expected to optimize urological applications of this robotic technology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980046"}
{"pmid": "20980047", "title": "Poliomyelitis eradication: another step forward.", "content": "Poliomyelitis eradication: another step forward.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980047"}
{"pmid": "20980049", "title": "Competitive time- and density-dependent adhesion of staphylococci and osteoblasts on crosslinked poly(ethylene glycol)-based polymer coatings in co-culture flow chambers.", "content": "Competitive time- and density-dependent adhesion of staphylococci and osteoblasts on crosslinked poly(ethylene glycol)-based polymer coatings in co-culture flow chambers. Biomaterial-associated infections (BAI) remain a serious clinical complication, often arising from an inability of host tissue-implant integration to out-compete bacterial adhesion and growth. A commercial polymer coating based on polyethylene glycol (PEG), available in both chemically inert and NHS-activated forms (OptiChem(®)), was compared for simultaneous growth of staphylococci and osteoblasts. In the absence of staphylococci, osteoblasts adhered and proliferated well on glass controls and on the NHS-reactive PEG-based coating over 48 h, but not on the inert PEG coating. Staphylococcal growth was low on both PEG-based coatings. When staphylococci were pre-adhered on surfaces for 1.5 h to mimic peri-operative contamination, osteoblast growth and spreading was reduced on glass but virtually absent on both reactive and inert PEG-based coatings. Thus although NHS-reactive, PEG-based coatings stimulated tissue-cell interactions in the absence of contaminating staphylococci, the presence of adhering staphylococci eliminated osteoblast adhesion advantages on the PEG surface. This study demonstrates the importance of using bacterial and cellular co-cultures compared to monocultures when assessing functionalized biomaterials coatings for infectious potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980049"}
{"pmid": "20980048", "title": "Immunogenicity of bivalent types 1 and 3 oral poliovirus vaccine: a randomised, double-blind, controlled trial.", "content": "Immunogenicity of bivalent types 1 and 3 oral poliovirus vaccine: a randomised, double-blind, controlled trial. Poliovirus types 1 and 3 co-circulate in poliomyelitis-endemic countries. We aimed to assess the immunogenicity of a novel bivalent types 1 and 3 oral poliovirus vaccine (bOPV). We did a randomised, double-blind, controlled trial to assess the superiority of monovalent type 2 OPV (mOPV2), mOPV3, or bOPV over trivalent OPV (tOPV), and the non-inferiority of bivalent vaccine compared with mOPV1 and mOPV3. The study was done at three centres in India between Aug 6, 2008, and Dec 26, 2008. Random allocation was done by permuted blocks of ten. The primary outcome was seroconversion after one monovalent or bivalent vaccine dose compared with a dose of trivalent vaccine at birth. The secondary endpoints were seroconversion after two vaccine doses compared with after two trivalent vaccine doses and cumulative two-dose seroconversion. Parents or guardians and study investigators were masked to treatment allocation. Because of multiple comparisons, we defined p≤0·01 as statistically significant. This trial is registered with Current Controlled Trials, ISRCTN 64725429. 900 newborn babies were randomly assigned to one of five vaccine groups (about 180 patients per group); of these 70 (8%) discontinued, leaving 830 (92%) for analysis. After the first dose, seroconversion to poliovirus type 1 was 20% for both mOPV1 (33 of 168) and bOPV (32 of 159) compared with 15% for tOPV (25 of 168; p>0·01), to poliovirus type 2 was 21% (35 of 170) for mOPV2 compared with 25% (42 of 168) for tOPV (p>0·01), and to poliovirus type 3 was 12% (20 of 165) for mOPV3 and 7% (11 of 159) for bOPV compared with 4% (7 of 168) for tOPV (mOPV3 vs tOPV p=0·01; bOPV vs tOPV; p>0·01). Cumulative two-dose seroconversion to poliovirus type 1 was 90% (151 of 168) for mOPV1 and 86% (136 of 159) for bOPV compared with 63% (106 of 168) for tOPV (p<0·0001), to poliovirus type 2 was 90% (153 of 170) for mOPV2 compared with 91% (153 of 168) for tOPV (p>0·01), and to poliovirus type 3 was 84% (138 of 165) for mOPV3 and 74% (117 of 159) for bOPV compared with 52% (87 of 168) for tOPV (p<0·0001). The vaccines were well tolerated. 19 serious adverse events occurred, including one death; however, these events were not attributed to the trial interventions. The findings show the superiority of bOPV compared with tOPV, and the non-inferiority of bOPV compared with mOPV1 and mOPV3. GAVI Alliance, World Health Organization, and Panacea Biotec.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980048"}
{"pmid": "20980050", "title": "Chitosan/poly(epsilon-caprolactone) blend scaffolds for cartilage repair.", "content": "Chitosan/poly(epsilon-caprolactone) blend scaffolds for cartilage repair. Chitosan (CHT)/poly(ɛ-caprolactone) (PCL) blend 3D fiber-mesh scaffolds were studied as possible support structures for articular cartilage tissue (ACT) repair. Micro-fibers were obtained by wet-spinning of three different polymeric solutions: 100:0 (100CHT), 75:25 (75CHT) and 50:50 (50CHT) wt.% CHT/PCL, using a common solvent solution of 100 vol.% of formic acid. Scanning electron microscopy (SEM) analysis showed a homogeneous surface distribution of PCL. PCL was well dispersed throughout the CHT phase as analyzed by differential scanning calorimetry and Fourier transform infrared spectroscopy. The fibers were folded into cylindrical moulds and underwent a thermal treatment to obtain the scaffolds. μCT analysis revealed an adequate porosity, pore size and interconnectivity for tissue engineering applications. The PCL component led to a higher fiber surface roughness, decreased the scaffolds swelling ratio and increased their compressive mechanical properties. Biological assays were performed after culturing bovine articular chondrocytes up to 21 days. SEM analysis, live-dead and metabolic activity assays showed that cells attached, proliferated, and were metabolically active over all scaffolds formulations. Cartilaginous extracellular matrix (ECM) formation was observed in all formulations. The 75CHT scaffolds supported the most neo-cartilage formation, as demonstrated by an increase in glycosaminoglycan production. In contrast to 100CHT scaffolds, ECM was homogenously deposited on the 75CHT and 50CHT scaffolds. Although mechanical properties of the 50CHT scaffold were better, the 75CHT scaffold facilitated better neo-cartilage formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980050"}
{"pmid": "20980051", "title": "Biocompatibility and osteogenesis of biomimetic Bioglass-Collagen-Phosphatidylserine composite scaffolds for bone tissue engineering.", "content": "Biocompatibility and osteogenesis of biomimetic Bioglass-Collagen-Phosphatidylserine composite scaffolds for bone tissue engineering. A novel biomimetic composite scaffold Bioglass-Collagen-Phosphatidylserine (BG-COL-PS) was fabricated with a freeze-drying technique. The macrostructure and morphology as well as mechanical strength of the scaffolds were characterized. Scanning electronic microscopy (SEM) showed that the BG-COL-PS scaffolds exhibited interconnected porous structures with pore sizes of several microns up to about 300 μm. The scaffolds have a porosity of 75.40% and the corresponding compressive strength of 1.5469 Mpa. Rat mesenchymal stem cells (rMSCs) were seeded on BG-COL-PS or BG-COL scaffolds and cultured for 21 days in vitro. Based on the results of SEM, dsDNA content, alkaline phosphatase (ALP) activity, osteogenic gene expression analysis and alizarin red staining, the responses of MSCs to the scaffold exhibited a higher degree of attachment, growth as well as osteogenic differentiation than those on BG-COL scaffolds in vitro. To investigate the in vivo biocompatibility and osteogenesis of the composite scaffolds, both pure BG-COL-PS scaffolds and MSC/scaffold constructs were implanted in rat femurs defects for 6 weeks and studied histologically and radiographically. The in vivo results showed that BG-COL-PS composite scaffolds exhibited good biocompatibility and extensive osteoconductivity with host bone. Moreover, the BG-COL-PS/MSC constructs dramatically enhanced the efficiency of new bone formation than pure BG-COL-PS scaffolds or BG-COL/MSC constructs. All these results demonstrate the usefulness of PS composited BG-COL-PS scaffolds for inducing enhanced bone formation. The BG-COL-PS scaffolds fulfill the basic requirements of bone tissue engineering scaffold and have the potential to be applied in orthopedic and reconstructive surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980051"}
{"pmid": "20980052", "title": "RANKL-induced TRPV2 expression regulates osteoclastogenesis via calcium oscillations.", "content": "RANKL-induced TRPV2 expression regulates osteoclastogenesis via calcium oscillations. The receptor activator of NFκB ligand (RANKL) induces Ca(2+) oscillations and activates the Nuclear Factor of Activated T cells 1 (NFATc1) during osteoclast differentiation (osteoclastogenesis). Ca(2+) oscillations are an important trigger signal for osteoclastogenesis, however the molecular basis of Ca(2+) permeable influx pathways serving Ca(2+) oscillations has not yet been identified. Using a DNA microarray, we found that Transient Receptor Potential Vanilloid channels 2 (TRPV2) are expressed significantly in RANKL-treated RAW264.7 cells (preosteoclasts) compared to untreated cells. Therefore, we further investigated the expression and functional role of TRPV2 on Ca(2+) oscillations and osteoclastogenesis. We found that RANKL dominantly up-regulates TRPV2 expression in preosteoclasts, and evokes spontaneous Ca(2+) oscillations and a transient inward cation current in a time-dependent manner. TRPV inhibitor ruthenium red and tetracycline-induced TRPV2 silencing significantly decreased both the frequency of Ca(2+) oscillations and the transient inward currents in RANKL-treated preosteoclasts. Silencing of store-operated Ca(2+) entry (SOCE) proteins similarly suppressed both RANKL-induced oscillations and currents in preosteoclasts. Furthermore, suppression of TRPV2 also reduced RANKL-induced NAFTc1 expression, its nuclear translocation, and osteoclastogenesis. In summary, Ca(2+) oscillations in preosteoclasts are triggered by RANKL-dependent TRPV2 and SOCE activation and intracellular Ca(2+) release. Subsequent activation of NFATc1 promotes osteoclastogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980052"}
{"pmid": "20980053", "title": "Novel variant form of t(11;22)(q23;q13)/MLL-EP300 fusion transcript in the evolution of an acute myeloid leukemia with myelodysplasia-related changes.", "content": "Novel variant form of t(11;22)(q23;q13)/MLL-EP300 fusion transcript in the evolution of an acute myeloid leukemia with myelodysplasia-related changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980053"}
{"pmid": "20980055", "title": "Volunteer and user evaluation of the National Sexual Assault Online Hotline.", "content": "Volunteer and user evaluation of the National Sexual Assault Online Hotline. The National Sexual Assault Online Hotline (NSAOH) is a new model for delivery of rape and sexual assault crisis services through a secure, confidential chat-based online hotline. This paper presents a program evaluation drawn from volunteer counselor and user perceptions and experiences during the second year of operation of the NSAOH. Outcome data are presented from 731 session evaluations submitted by 94 volunteers and session evaluations from 4609 user sessions collected between June 1, 2008 and May 30, 2009. Evaluation includes ratings of usefulness, topics discussed, length of sessions, services provided, and session difficulties. The results indicate that the model is viable and useful, and the majority of volunteers and users are satisfied. Volunteer knowledge and skills are strongly associated with satisfaction with the hotline. Nevertheless, one-fifth of volunteers rate their session as not useful and users rate 8.2% of volunteers low in knowledge and skills. NSAOH is reaching many who have not previously sought services or did not resolve issues through other means. Findings suggest the importance of preparing volunteers in both crisis intervention and a wide variety of long-term issues related to sexual assault. Recommendations for program development, evaluation, and further research are presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980055"}
{"pmid": "20980054", "title": "Development of microbial engineered whole-cell systems for environmental benzene determination.", "content": "Development of microbial engineered whole-cell systems for environmental benzene determination. This paper reports the development of two recombinant bacterial systems that can be used to monitor environmental benzene contamination based on Escherichia coli, which carry genes coding for benzene dioxygenase and benzene dihydrodiol dehydrogenase from Pseudomonas putida MST. E. coli strains express these two enzymes under the control of the Ptac promoter or without any induction. These activities can be detected electrochemically or colorimetrically and used to monitor benzene pollution in environmental air samples collected from an oil refinery assessing benzene by different laboratory experimental procedures. The procedures involving whole-cell bioassays determine the concentration of benzene through benzene dioxygenase activity, which allows for direct correlation of oxygen consumption, and through the benzene dihydrodiol dehydrogenase that causes catechol accumulation and restores NADH necessary for the activity of the first enzyme. Oxygen consumption and catechol production deriving from both enzymatic activities are related to benzene concentration and their measurements determined the sensitivity of the system. The results indicated that the sensitivity was enough to detect the benzene vapor at a lower concentration level of 0.01 mM in about 30 min. The possibility for on-line monitoring of benzene concentration by our new recombinant cells results from the fact that no particular treatment of environmental samples is required. This is a major advantage over other biosensors or assays. Moreover, the development of microbial cells that did not require any addition or effectors for the transcription of the specific enzymes, allowed these systems to be more versatile in automated environmental benzene monitoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980054"}
{"pmid": "20980057", "title": "Testing sex and gender in sports; reinventing, reimagining and reconstructing histories.", "content": "Testing sex and gender in sports; reinventing, reimagining and reconstructing histories. Most international sports organisations work on the premise that human beings come in one of two genders: male or female. Consequently, all athletes, including intersex and transgender individuals, must be assigned to compete in one or other category. Since the 1930s (not, as is popularly suggested, the 1960s) these organisations have relied on scientific and medical professionals to provide an 'objective' judgement of an athlete's eligibility to compete in women's national and international sporting events. The changing nature of these judgements reflects a great deal about our cultural, social and national prejudices, while the matter of testing itself has become a site of conflict for feminists and human rights activists. Because of the sensitive nature of this subject, histories of sex testing are difficult to write and research; this has lead to the repetition of inaccurate information and false assertions about gender fraud, particularly in relation to the 'classic' cases of Stella Walsh and Heinrich/Hermann/Dora Ratjen. As historians, we need to be extremely careful to differentiate between mythologies and histories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980057"}
{"pmid": "20980058", "title": "Cytokine induction by immunostimulatory DNA in porcine PBMC is impaired by a hairpin forming sequence motif from the genome of Porcine Circovirus type 2 (PCV2).", "content": "Cytokine induction by immunostimulatory DNA in porcine PBMC is impaired by a hairpin forming sequence motif from the genome of Porcine Circovirus type 2 (PCV2). Porcine Circovirus type 2 (PCV2) can cause postweaning multisystemic wasting syndrome (PMWS) in young pigs with severe immunosuppression as a major characteristic of the disease complex. Despite the dramatic involvement of the immune system, the interaction between PCV2 and the host is until date not well understood. The DNA genome of PCV2 contains sequences that in synthetic form (oligodeoxyribonucleotides; ODNs) can act immunomodulatory on porcine peripheral blood mononuclear cells (poPBMCs) in vitro. One such sequence (ODN PCV2/1) acts inhibitory on interferon (IFN)-α production induced by immunostimulatory DNA but not that induced by RNA, and the inhibitory activity is dependent on secondary structure formation. In the present study, the characteristic of ODN PCV2/1 was examined further by altering the nucleotide sequence to disrupt hairpin structure formation but still enable multimer structures through G-tetrads. This modification resulted in loss of IFN-α-inhibitory activity of the ODN and thus indicated the importance of hairpin structures. In addition, ODN PCV2/1 was compared to another inhibitory ODN (IRS 869) previously used in human and murine cells. In contrast to ODN PCV2/1, ODN IRS 869 did not inhibit IFN-α production induced by class A ODN 2216 but was a more efficient inhibitor of IFN-α production induced by plasmid DNA than ODN PCV2/1. In cultures induced by the RNA stimulator Poly I:C, however, a strong synergistic IFN-α stimulatory effect was seen in combination with ODN IRS 869. These results indicate that ODN PCV2/1 and ODN IRS 869 function through separate mechanisms to affect cytokine production by immune cells. The effect of ODN PCV2/1 was studied further by monitoring the expression of mRNA for IFN-α, IL-12p40, IL-10, IL-6, IFN-γ, IL-1β, TGF-β, and TNF-α in cultures of poPBMC stimulated with ODN 2216 or Poly I:C. Results from qPCR analyses showed that ODN PCV2/1 clearly inhibited the expression of IFN-α, IL-12p40, IL-10 and IL-6 when induced by ODN 2216, but did not seem to affect any of the cytokines examined when induced by Poly I:C. Initial studies using confocal microscopy and fluorochrome labelled ODNs indicate that ODN 2216 and ODN PCV2/1 co-localize in subpopulations of poPBMC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980058"}
{"pmid": "20980059", "title": "Expression of four canine leukocyte adhesion factors in fresh and stored whole blood samples evaluated using a no-lyse, no-wash method.", "content": "Expression of four canine leukocyte adhesion factors in fresh and stored whole blood samples evaluated using a no-lyse, no-wash method. Expression of four leukocyte adhesion factors on canine leukocytes was studied by flow cytometry using a no-lyse, no-wash method. The effect of fixation and storage for up to 14 days in 1% paraformaldehyde on labelled samples and within assay variation was evaluated. Monoclonal antibodies directed to monocyte marker CD14, and to adhesion molecules CD11a, CD18, CD32 and CD49d were used. Cell surface marker, cell population, time, and the interactions between time and cell marker significantly affected expression of cell adhesion factors. For CD18, there was a significant difference in mean fluorescence intensity (MFI) between fresh and stored samples (P<0.001), but no significant difference between stored samples. The MFIs of CD11a and CD49d were not significantly affected by fixation and storage. The CVs differed significantly depending on cell marker (P<0.001) and cell population (P=0.005). Fixation and storage did not significantly affect the CV. In conclusion, a no-lyse, no-wash method can be applied to canine leukocytes. The effect of fixation and storage on the resulting MFI differs between monoclonal antibodies, and should be evaluated for each antibody before use. The coefficient of variation was generally acceptable, and high CVs were related to a low MFIs or low numbers of analysed cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980059"}
{"pmid": "20980060", "title": "In vitro effect of different mediators of apoptosis on canine cranial and caudal cruciate ligament fibroblasts and its reversibility by pancaspase inhibitor zVAD.fmk.", "content": "In vitro effect of different mediators of apoptosis on canine cranial and caudal cruciate ligament fibroblasts and its reversibility by pancaspase inhibitor zVAD.fmk. Primary fibroblast cultures of canine cranial (CCL) and caudal (CaCL) cruciate ligaments were stimulated with different apoptosis inducers with or without preincubation of the pancaspase inhibitor zVAD.fmk. In contrast to CaCL fibroblasts, fibroblasts from CCL were significantly more susceptible to apoptosis inducers of the intrinsic pathway like doxorubicin, cisplatin and nitric oxide (NO)-donors and to Fas ligand (FasL), an apoptosis inducer of the death receptor pathway. Apoptotic response to staurosporine and the peroxynitrite donor GEA was similar in both ligament fibroblasts. Stimulation with dexamethasone or TNFα could not induce apoptosis in CCL and CaCL fibroblasts, in spite of present TNFR1 and TNFR2 receptors. zVAD.fmk was able to prevent apoptosis in up to 66% of CCL cells when treated with FasL, cisplatin or doxorubicin but it had no effect on NO or peroxynitrite induced apoptosis. In conclusion, differential susceptibility to apoptotic triggers like FasL or NO between cranial and caudal cruciate ligament fibroblasts in vitro may be a reflection of the different susceptibilities to degenerative rupture of the ligament. These findings indicate that a general caspase inhibition does not completely protect canine CCL cells from apoptosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980060"}
{"pmid": "20980061", "title": "Endoscopic anterior cricoid split and balloon dilation in pediatric subglottic stenosis.", "content": "Endoscopic anterior cricoid split and balloon dilation in pediatric subglottic stenosis. To analyze the outcome of a new endoscopic approach for the treatment of pediatric subglottic stenosis. Case series. Tertiary care center. Eighteen pediatric cases of grade II to IV subglottic stenosis (8 congenital and 10 acquired) consecutively treated at our institutions by Endoscopic Anterior Cricoid Split (EACS) and balloon dilation between 2006 and 2010. Treatment protocol encompassed systematic postoperative laryngeal stenting (7 days of intubation or 1 month of Montgomery T-tube in previously tracheotomized patients) and endoscopic controls with possible additional balloon dilation every 15 days for at least 2 months. Patients' ages ranged from 1 to 101 months. Postoperative follow-up ranged from 4 to 45 months (median value±SD: 15.3±11.9). The mean duration of the endoscopic procedure was 35.2±13.2 min. The number of days spent in PICU during the perioperative period varied between 2 and 15. Four patients (22.2%) needed one and 14 patients (77.7%) required several (from 4 to 7) additional balloon dilations during the postoperative endoscopic controls. No incident was observed during or immediately after EACS. Treatment was efficient in 83% of cases (n=15), with no residual respiratory symptoms and grade 0 to 1 SGS at the end of follow-up. EACS is a safe and efficient technique to treat pediatric subglottic stenosis, regardless of their grade and length, provided to associate it with postoperative laryngeal stenting and regular endoscopic follow-up with possible additional balloon dilations. In our teams, it has become the first line treatment for most grades II to IV SGS. Its indications can be extended to congenital stenosis with cartilaginous involvement and to long-lasting acquired stenosis with firm fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980061"}
{"pmid": "20980056", "title": "A testable theory of problem solving courts: Avoiding past empirical and legal failures.", "content": "A testable theory of problem solving courts: Avoiding past empirical and legal failures. Recent years have seen a proliferation of problem solving courts designed to rehabilitate certain classes of offenders and thereby resolve the underlying problems that led to their court involvement in the first place. Some commentators have reacted positively to these courts, considering them an extension of the philosophy and logic of Therapeutic Jurisprudence, but others show concern that the discourse surrounding these specialty courts has not examined their process or outcomes critically enough. This paper examines that criticism from historical and social scientific perspectives. The analysis culminates in a model that describes how offenders are likely to respond to the process as they engage in problem solving court programs and the ways in which those courts might impact subsequent offender conduct. This Therapeutic Jurisprudence model of problem solving courts draws heavily on social cognitive psychology and more specifically on theories of procedural justice, motivation, and anticipated emotion to offer an explanation of how offenders respond to these programs. We offer this model as a lens through which social scientists can begin to address the concern that there is not enough critical analysis of the process and outcome of these courts. Applying this model to specialty courts constitutes an important step in critically examining the contribution of problem solving courts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980056"}
{"pmid": "20980062", "title": "TLR-9, NOD-1, NOD-2, RIG-I and immunoglobulins in recurrent otitis media with effusion.", "content": "TLR-9, NOD-1, NOD-2, RIG-I and immunoglobulins in recurrent otitis media with effusion. Pattern recognition receptors (PRRs) induce appropriate immune responses after recognizing certain molecular characteristics of pathogens. It is not known, however, whether PRRs are expressed in middle ear infections and whether the expression of PRRs and immunoglobulins is correlated in recurrent otitis media with effusion (OME). We therefore investigated the expression of PRRs and immunoglobulins in children with OME. The study population consisted of 66 children with OME, of whom 27 had more than 4 episodes in 12 months or more than 3 episodes in 6 months (otitis-prone group), and 39 had fewer than 4 episodes in 12 months or 3 episodes in 6 months (non-otitis-prone group). The expression in middle ear effusion of Toll-like receptor (TLR)-9, nucleotide-binding oligomerization domain (NOD)-1, NOD-2, and retinoic acid-inducible gene (RIG)-I mRNA, as determined by real-time PCR, and the concentrations of IgG, IgA, and IgM, as determined by ELISA, were compared between the two groups. The levels of TLR-9, NOD-1 and RIG I mRNAs were significantly lower in the otitis-prone than in the non-otitis-prone group (p<0.05 each). The concentrations of IgG, IgA and IgM in effusion fluid did not differ significantly between the two groups (p>0.05), and there were no correlations between immunoglobulin concentration and the expression of PRPs (p>0.05). Decreased expression of PRRs may be associated with increased susceptibility to OME.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980062"}
{"pmid": "20980063", "title": "Targeting the correct HDAC(s) to treat cognitive disorders.", "content": "Targeting the correct HDAC(s) to treat cognitive disorders. Changes in gene expression in the brain may underlie cognitive deficits inherent to normal aging and neurodegenerative disease. However, the mechanisms underlying pathological alterations in the brain transcriptome are incompletely understood. Epigenetic mechanisms such as DNA methylation and histone acetylation have been shown to be important for memory processes in the adult brain. There is accumulating evidence that altered chromatin plasticity and histone acetylation are also involved in cognitive aging, neurodegeneration, and neuropsychiatric diseases. Inhibitors of histone deacetylase (HDAC) exhibit neuroprotective and neuroregenerative properties in animal models of various brain diseases. As such, targeting of HDACs seems to be a promising therapeutic strategy. In this review, we discuss the specific roles of each HDAC protein and the possible function of distinct histone modifications. We hope that this knowledge will aid in the development of diagnostic tools and in designing more potent and specific treatment for neurological disorders targeting selective HDAC proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980063"}
{"pmid": "20980064", "title": "Is adult neurogenesis essential for olfaction?", "content": "Is adult neurogenesis essential for olfaction? In mammals, new neurons are recruited into restricted brain areas throughout life. Adult-born neurons produced in the subventricular zone of the lateral ventricle migrate rostrally towards the olfactory bulb. Although thousands of neurons reach this central structure every day, the functional impact of their integration into mature circuits remains a matter of debate. Recent investigations have revealed no striking sensory deficits per se when adult bulbar neurogenesis is challenged. However, some cognitive functions, such as perceptual learning and olfactory memory, are clearly impaired. In this review we highlight the role of network activity in shaping ongoing neurogenesis and, in turn, how the integration of adult-born neurons refines pre-existing network function, and consequently olfactory behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980064"}
{"pmid": "20980065", "title": "Evaluating the Type II error rate in a sediment toxicity classification using the Reference Condition Approach.", "content": "Evaluating the Type II error rate in a sediment toxicity classification using the Reference Condition Approach. Sediments from 71 river sites in Northern Spain were tested using the oligochaete Tubifex tubifex (Annelida, Clitellata) chronic bioassay. 47 sediments were identified as reference primarily from macroinvertebrate community characteristics. The data for the toxicological endpoints were examined using non-metric MDS. Probability ellipses were constructed around the reference sites in multidimensional space to establish a classification for assessing test-sediments into one of three categories (Non Toxic, Potentially Toxic, and Toxic). The construction of such probability ellipses sets the Type I error rate. However, we also wished to include in the decision process for identifying pass-fail boundaries the degree of disturbance required to be detected, and the likelihood of being wrong in detecting that disturbance (i.e. the Type II error). Setting the ellipse size to use based on Type I error does not include any consideration of the probability of Type II error. To do this, the toxicological response observed in the reference sediments was manipulated by simulating different degrees of disturbance (simpacted sediments), and measuring the Type II error rate for each set of the simpacted sediments. From this procedure, the frequency at each probability ellipse of identifying impairment using sediments with known level of disturbance is quantified. Thirteen levels of disturbance and seven probability ellipses were tested. Based on the results the decision boundary for Non Toxic and Potentially Toxic was set at the 80% probability ellipse, and the boundary for Potentially Toxic and Toxic at the 95% probability ellipse. Using this approach, 9 test sediments were classified as Toxic, 2 as Potentially Toxic, and 13 as Non Toxic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980065"}
{"pmid": "20980066", "title": "Assessing combined toxicity of estrogen receptor agonists in a primary culture of rainbow trout (Oncorhynchus mykiss) hepatocytes.", "content": "Assessing combined toxicity of estrogen receptor agonists in a primary culture of rainbow trout (Oncorhynchus mykiss) hepatocytes. The presence of highly complex mixtures of chemicals in the environment challenges our ability to assess single chemical effects and the interaction that occurs with cellular receptor targets and regulation of endocrine processes. In this study concentration addition (CA) and independent action (IA) prediction models were used to assess the combined toxicity of mixtures of environmental relevant estrogen receptor (ER) agonists (hormones and anthropogenic pollutants) in a primary culture of rainbow trout (Oncorhynchus mykiss) hepatocytes using the ER-mediated production of vitellogenin (Vtg) as a biological marker (biomarker) for estrogenicity. Nine of the eleven tested chemicals induced the production of Vtg and the parameters from the fitted concentration-response curves were used to model four mixtures containing four (17β-estradiol, estrone, estriol and diethylstilbestrol), five (musk ketone, 4-tert-octylphenol, bisphenol A, o,p'-DDT and dibenzothiophene), seven (17β-estradiol, estrone, estriol, diethylstilbestrol, 4-tert-octylphenol, bisphenol A and o,p'-DDT) and nine compounds (17β-estradiol, estrone, estriol, diethylstilbestrol, musk ketone, 4-tert-octylphenol, bisphenol A, o,p'-DDT and dibenzothiophene). The CA and IA prediction model proved to be a good estimation for the combined effect of mixtures of ER agonists at low relative mixture concentration (e.g. relative to the maximum mixture concentrations used), but a deviation from the prediction models was observed when exposing hepatocytes to high relative mixture concentrations. The CA and IA prediction models' ability to predict the combined estrogenic effect of complex mixtures, especially in the low concentration-response range, is of ecological relevance since organisms in the environment generally encounter low concentrations of chemicals from a wide array of chemical groups that may not elicit estrogenic effects on their own.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980066"}
{"pmid": "20980067", "title": "Fathead minnow (Pimephales promelas) reproduction is impaired in aged oil sands process-affected waters.", "content": "Fathead minnow (Pimephales promelas) reproduction is impaired in aged oil sands process-affected waters. Large volumes of fluid tailings are generated during the extraction of bitumen from oil sands. As part of their reclamation plan, oil sands operators in Alberta propose to transfer these fluid tailings to end pit lakes and, over time, these are expected to develop lake habitats with productive capabilities comparable to natural lakes in the region. This study evaluates the potential impact of various oil sands process-affected waters (OSPW) on the reproduction of adult fathead minnow (Pimephales promelas) under laboratory conditions. Two separate assays with aged OPSW (>15 years) from the experimental ponds at Syncrude Canada Ltd. showed that water containing high concentrations of naphthenic acids (NAs; >25 mg/l) and elevated conductivity (>2000 μS/cm) completely inhibited spawning of fathead minnows and reduced male secondary sexual characteristics. Measurement of plasma sex steroid levels showed that male fathead minnows had lower concentrations of testosterone and 11-ketotestosterone whereas females had lower concentrations of 17β-estradiol. In a third assay, fathead minnows were first acclimated to the higher salinity conditions typical of OSPW for several weeks and then exposed to aged OSPW from Suncor Energy Inc. (NAs ∼40 mg/l and conductivity ∼2000 μS/cm). Spawning was significantly reduced in fathead minnows held in this effluent and male fathead minnows had lower concentrations of testosterone and 11-ketotestosterone. Collectively, these studies demonstrate that aged OSPW has the potential to negatively affect the reproductive physiology of fathead minnows and suggest that aquatic habitats with high NAs concentrations (>25 mg/l) and conductivities (>2000 μS/cm) would not be conducive for successful fish reproduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980067"}
{"pmid": "20980068", "title": "Spheric balloon technique for ostial bifurcation lesion treatment.", "content": "Spheric balloon technique for ostial bifurcation lesion treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980068"}
{"pmid": "20980069", "title": "Peripheral chemosensor function is blunted in moderate to severe chronic kidney disease.", "content": "Peripheral chemosensor function is blunted in moderate to severe chronic kidney disease. Cardiovascular mortality is markedly increased in chronic kidney disease (CKD) and may be explained in part by sympathetic hyperactivity. Impaired hyperoxic chemoreflex sensitivity (CHRS) has been attributed to an increased sympathetic tone. The aim of the present study was to examine whether chemosensor function is altered in patients with CKD. We assessed CHRS in 20 patients with stage 3 CKD [glomerular filtration rate (GFR) 30-59 ml/min/1.73 m(2)], in 15 patients with stage 4 CKD [GFR 15-29 ml/min/1.73 m(2)], as well as in 35 age and gender matched patients without any evidence of CKD. The difference in the R-R intervals divided by the difference in the oxygen pressures before and after deactivation of the chemoreceptors by inhalation of pure oxygen was calculated as the CHRS. A CHRS below 3.0 ms/mmHg was defined as pathological. CHRS was significantly depressed in patients with stage 3 CKD (2.9 ± 0.9 ms/mmHg, P=0.005) and in patients with stage 4 CKD (2.1 ± 0.6 ms/mmHg, P<0.001), as compared with patients without CKD (6.7 ± 0.9 ms/mmHg). There was a negative correlation between serum creatinine and CHRS (r=-0.51; P<0.001). In patients with CKD, chemosensor deactivation decreased mean arterial pressure from 91 ± 4 mmHg to 87 ± 3 mmHg (P=0.03). Multivariate analysis showed that GFR (P=0.001) was the only independent predictor of a pathological CHRS. Using a relatively non-invasive bedside test we provide evidence for a blunted peripheral chemosensor function in chronic kidney disease. We thereby lay the basis for interventional studies assessing chemosensor function in chronic kidney disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980069"}
{"pmid": "20980070", "title": "Field trial of a synthetic tsetse-repellent technology developed for the control of bovine trypanosomosis in Kenya.", "content": "Field trial of a synthetic tsetse-repellent technology developed for the control of bovine trypanosomosis in Kenya. We conducted a field trial among Maasai cattle-keepers in Nkuruman and Nkineji areas of Kenya to evaluate the effectiveness of a synthetic tsetse-repellent technology developed for the control of trypanosomosis in cattle. The technology was a repellent (2-methoxy 4-methylphenol) emitted from dispensers attached to collars worn by cattle. Treatment was allocated at the herd level to ensure adequate protection of all the animals in a herd, with measurements of effectiveness conducted at the individual-animal level. The trial began in April 2005 and ran for 16 months including a baseline phase of 4 months. We recruited 12 herds in each area using a restricted random-sampling technique and distributed them equally into intervention (repellent) and control groups. Sample size was determined using a formal power calculation. Effectiveness or minimal worthwhile difference was defined as a 50% reduction in the incidence of trypanosome infection in the treated versus control group (effectiveness below which the technology was considered by experts as not viable compared to existing control techniques). All the animals in the recruited herds were screened monthly (buffy-coat technique) for trypanosome infections. The analysis followed the principle of intention-to-treat by which subjects are analysed according to their initial treatment assignment, regardless of the mechanical performance of the device. Crude and adjusted effects of the technology were 23% (p<0.001) and 18% (p=0.08) reduction in the infection incidence in the treatment compared to the control groups, respectively. The impact of the technology estimated in this study did not achieve the threshold of 50% reduction in the trypanosome infection incidence set a priori to indicate effectiveness (p<0.001). We therefore concluded that the prototype repellent technology package was not sufficiently effective in reducing trypanosome infection incidence under natural tsetse challenge to merit commercial development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980070"}
{"pmid": "20980071", "title": "Geochemical interactions between process-affected water from oil sands tailings ponds and North Alberta surficial sediments.", "content": "Geochemical interactions between process-affected water from oil sands tailings ponds and North Alberta surficial sediments. In Northern Alberta, the placement of out-of-pit oil sands tailings ponds atop natural buried sand channels is becoming increasingly common. Preliminary modeling of such a site suggests that process-affected (PA) pond water will infiltrate through the underlying clay till aquitard, reaching the sand channel. However, the impact of seepage upon native sediments and groundwater resources is not known. The goal of this study is to investigate the role of adsorption and ion exchange reactions in the clay till and their effect on the attenuation or release of inorganic species. This was evaluated using batch sorption experiments (traditional and a recent modification using less disturbed sediment samples) and geochemical modeling with PHREEQC. The results show that clay till sediments have the capacity to mitigate the high concentrations of ingressing sodium (600 mg L(-1)), with linear sorption partitioning coefficients (K(d)) of 0.45 L kg(-1). Ion exchange theory was required to account for all other cation behaviour, precluding the calculation of such coefficients for other species. Qualitative evidence suggests that chloride will behave conservatively, with high concentrations remaining in solution (375 mg L(-1)). As a whole, system behaviour was found to be controlled by a combination of competitive ion exchange, dissolution and precipitation reactions. Observations, supported by PHREEQC simulations, suggest that the influx of PA water will induce the dissolution of pre-existing sulphate salts. Sodium present in the process-affected water will exchange with sediment-bound calcium and magnesium, increasing the divalent ions' pore fluid concentrations, and leading to the precipitation of a calcium-magnesium carbonate mineral phase. Thus, in similar tailings pond settings, particularly if the glacial till coverage is thin or altogether absent, it is reasonable to expect that high concentrations of sodium and chloride will remain in solution, while sulphate concentrations will exceed those of the ingressing plume (150 mg L(-1)).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980071"}
{"pmid": "20980072", "title": "Proteome analysis of sugar beet (Beta vulgaris L.) elucidates constitutive adaptation during the first phase of salt stress.", "content": "Proteome analysis of sugar beet (Beta vulgaris L.) elucidates constitutive adaptation during the first phase of salt stress. Salinity is one of the major stress factors responsible for growth reduction of most of the higher plants. In this study, the effect of salt stress on protein pattern in shoots and roots of sugar beet (Beta vulgaris L.) was examined. Sugar beet plants were grown in hydroponics under control and 125 mM salt treatments. A significant growth reduction of shoots and roots was observed. The changes in protein expression, caused by salinity, were monitored using two-dimensional gel-electrophoresis. Most of the detected proteins in sugar beet showed stability under salt stress. The statistical analysis of detected proteins showed that the expression of only six proteins from shoots and three proteins from roots were significantly altered. At this stage, the significantly changed protein expressions we detected could not be attributed to sugar beet adaptation under salt stress. However, unchanged membrane bound proteins under salt stress did reveal the constitutive adaptation of sugar beet to salt stress at the plasma membrane level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980072"}
{"pmid": "20980074", "title": "Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine.", "content": "Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine. The role of CB2 cannabinoid receptors in the behavioral and neurochemical changes induced by intracaudate administration of 6-hydroxydopamine (6-OHDA) was evaluated. 6-OHDA (12 μg/4 μL) or its vehicle was injected in the caudate-putamen (CPu) of mice overexpressing the CB2 cannabinoid receptor (CB2xP) and wild type (WT) mice. Motor impairment, emotional behavior, and cognitive alterations were evaluated. Tyrosine hydroxylase (TH), glial fibrillary acidic protein (GFAP), and ionized calcium-binding adapter molecule 1 (Iba-1) were measured by immunocytochemistry in the CPu and/or substantia nigra (SN) of CB2xP mice and WT mice. Oxidative/nitrosative and neuroinflammatory parameters were also measured in the CPu and cortex of 6-OHDA-treated and sham-treated mice. 6-OHDA-treated CB2xP mice presented significantly less motor deterioration than 6-OHDA-treated WT mice. Immunocytochemical analysis of tyrosine hydroxylase in the SN and CPu revealed significantly fewer lesions in CB2xP mice than in WT mice. GFAP and Iba-1 immunostaining revealed less astrocyte and microglia recruitment to the treated area of the CPu in CB2xP mice. Malonyldialdehyde (MDA) concentrations were lower in the striatum and cerebral cortex of sham-treated CB2xP mice than in sham-treated WT mice. The administration of 6-OHDA increased MDA levels in both WT mice and CB2xP mice; it increased the oxidized (GSSG)/reduced (GSH) glutathione ratio in the striatum in WT mice alone compared with matched sham-treated controls. The results revealed that overexpression of CB2 cannabinoid receptors decreased the extent of motor impairment and dopaminergic neuronal loss, reduced the recruitment of astrocytes and microglia to the lesion, and decreased the level of various oxidative parameters. These results suggest that CB2 receptors offer neuroprotection against dopaminergic injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980074"}
{"pmid": "20980075", "title": "SAP97-mediated local trafficking is altered in Alzheimer disease patients' hippocampus.", "content": "SAP97-mediated local trafficking is altered in Alzheimer disease patients' hippocampus. Synapse-asssociated protein-97 (SAP97) is responsible for the trafficking of both glutamate receptor subunits, GluR1 and NR2A, and α-secretase ADAM10 to the synaptic membrane. Here we evaluate the trafficking capability of SAP97 in Alzheimer disease (AD) patients' brain. We analyzed autoptic hippocampus and superior frontal gyrus, respectively as an affected and a less affected area, from 6 AD patients (Braak 4) and 6 healthy controls. In hippocampus, but not in superior frontal gyrus, of AD patients, ADAM10 and GluR1 synaptic membrane levels are altered while NR2A localization is not affected. Both immunoprecipitation and pull-down assays demonstrated that SAP97 failed to correctly couple to ADAM10 and GluR1, but not to NR2A. These findings not only indicate SAP97 as a point of convergence between amyloid cascade and synaptic failure in AD, but also allow a different interpretation of AD which can be now perceived as synaptic trafficking defect pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980075"}
{"pmid": "20980076", "title": "Serum fatty acid profiles using GC-MS and multivariate statistical analysis: potential biomarkers of Alzheimer's disease.", "content": "Serum fatty acid profiles using GC-MS and multivariate statistical analysis: potential biomarkers of Alzheimer's disease. Previous studies showed the relationship between fatty acids and the risk of developing Alzheimer's disease (AD). However, they did not address potential differences in free fatty acid (FFA) profiles that could be used to distinguish between AD patients and healthy controls. In the present study we used gas chromatography-mass spectrometry (GC-MS) technology coupled with multivariate statistical analysis to study profiles of FFA in AD. The results indicated 2 saturated fatty acids (C14:0 and C16:0; p < 0.001 and p < 0.05, respectively), 3 unsaturated fatty acids (C18:1, C18:3, and C22:6; p < 0.05, p < 0.05, and p < 0.001, respectively), where mean levels in serum from AD patients were significantly lower than controls. Partial least squares discriminant analysis (PLS-DA) models with unit variance (UV) scaling and orthogonal signal correction (OSC) data preprocessing methods were employed to refine intergroup differences between FFA profiles. The results of the analysis have highlighted docosahexaenoic acid (DHA) as the FFA with the greatest potential as a biomarker of AD, and this study has demonstrated that FFA biomarkers have considerable potential in diagnosing and monitoring AD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980076"}
{"pmid": "20980079", "title": "A neuroprotective sulfone of marine origin and the in vivo anti-inflammatory activity of an analogue.", "content": "A neuroprotective sulfone of marine origin and the in vivo anti-inflammatory activity of an analogue. Our continuing effort of searching bioactive substances from the Formosan soft coral Cladiella australis has led to the isolation of a bioactive substance austrasulfone (1), which possesses significant neuroprotective activities. A straightforward synthesis of 1 was achieved by a two-step reaction sequence. Dihydroaustrasulfone alcohol (3), the synthetic precursor of 1, not only exhibited in vitro anti-inflammatory activity, but also showed potent therapeutic ability in the treatment of neuropathic pain, atherosclerosis, and multiple sclerosis in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980079"}
{"pmid": "20980073", "title": "The impact of informal caregivers on depressive symptoms among older adults receiving formal home health care.", "content": "The impact of informal caregivers on depressive symptoms among older adults receiving formal home health care. This study evaluated the association between presence and types of informal caregivers and the presence of depressive symptoms among older adults receiving formal home health care (HHC). A secondary analysis of data was conducted using a computerized patient care database, the Outcome and Assessment Information Set. Logistic regression analyses were used to examine the data of 8448 patients aged 65 years or older who had been admitted to an HHC agency from acute care hospitals between January 1, 2002 and June 30, 2002. The outcome variable was the presence of depressive symptoms. The primary predictor variable was the presence and types of informal caregivers. Covariates included demographic variables, health status, length of time enrolled in formal HHC, patient living arrangements, and the frequency and types of care received from informal caregivers. A lower percentage of older adults receiving care from both informal caregivers and a formal HHC agency (13.3%) had depressive symptoms than older adults receiving only formal HHC (14.9%) at the end of a 60-day episode in formal HHC. Older adults without an informal caregiver were more likely to experience depressive symptoms than those with an informal caregiver after a 60-day episode in HHC (odds ratio = 1.229, 95% confidence interval = 1.027-1.471). There was no significant association between the types of informal caregivers and the presence of depressive symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980073"}
{"pmid": "20980080", "title": "Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents.", "content": "Biological evaluation of donor-acceptor aminonaphthoquinones as antitumor agents. Several members of the phenylamino-1,4-naphthoquinone series were prepared in order to investigate structure-activity relationships (SAR) and to explore the antitumor effects associated with this scaffold. The cytotoxic effects of the aminoquinones (EC50) against a panel of cancer cell lines (MCF7, DU145 and T24 cells) and healthy fibroblasts (BALB/3T3) were assessed in vitro using the MTT reduction assay 48 h after drug exposure. SAR analysis of the aminonaphthoquinone series showed that insertion of a chlorine atom in the acceptor quinone nucleus and/or insertion of a methyl group at the nitrogen atom of the donor phenylamino group induced significant changes in cytotoxic activity. Quinones 7 and 9, which exhibited the highest selective indexes (5.73 and 6.29, respectively), were further characterized using the following assays: Colony formation, caspase-3 activity, and ATP content. The results showed that aminoquinone 7 strongly influenced ATP levels and impaired the proliferative capacity of T24 cells without activating caspase-3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980080"}
{"pmid": "20980077", "title": "Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease.", "content": "Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease. Previous studies have shown association of single nucleotide polymorphisms (SNPs) in 3 contiguous genes (PON1, PON2, and PON3) encoding paraoxonase with risk of Alzheimer disease (AD). We evaluated the association of serum paraoxonase activity measured by phenyl acetate (PA) and thiobutyl butyrolactone (TBBL) with risk of AD and with 26 SNPs spanning the PON gene cluster in 266 AD cases and 306 sibling controls from the MIRAGE study. The odds of AD (adjusted for age, gender, and ethnicity) increased 20% for each standard deviation decrease in PA or TBBL activity. There were association signals with activity in all 3 genes. Haplotypes including SNPs spanning the PON genes were generally more significant than haplotypes comprising SNPs from 1 gene. Significant interactions were observed between SNP pairs located across the PON cluster with either serum activity measure as the outcome, and between several PON SNPs and PA activity with AD status as the outcome. Our results suggest that low serum paraoxonase activity is a risk factor for AD. Furthermore, multiple variants in PON influence serum paraoxonase activity and their effects may be synergistic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980077"}
{"pmid": "20980082", "title": "Forest fires in the former Soviet Union: no reasons for radiophobia.", "content": "Forest fires in the former Soviet Union: no reasons for radiophobia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980082"}
{"pmid": "20980083", "title": "Development of an energy discriminate CR-39(®) nuclear track etch dosimeter for Radon-220 gas measurements.", "content": "Development of an energy discriminate CR-39(®) nuclear track etch dosimeter for Radon-220 gas measurements. An energy discriminate CR-39(®) nuclear track etch dosimeter for use in a (220)Rn and (222)Rn gas monitor has been developed and experimentally assessed. It utilises a thin film of Mylar(®) C to attenuate the alpha particle energies to allow only the damage tracks created by the 8.785 MeV alpha particles emitted from (212)Po of the (232)Th decay chain to be registered in the CR-39(®) plaque, allowing for the direct measurement of (220)Rn gas concentrations. The dosimeter was developed through a combination of experimental investigations and theoretical simulations using the Monte Carlo ion transport modelling program Stopping and Range of Ions in Materials (SRIM 2008). A film thickness of 54 μm has been shown to attenuate all alpha energies less then 7.7 MeV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980083"}
{"pmid": "20980084", "title": "Re.: Development of in-house rapid manufacturing of three-dimensional models in maxillofacial surgery.", "content": "Re.: Development of in-house rapid manufacturing of three-dimensional models in maxillofacial surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980084"}
{"pmid": "20980085", "title": "Environmental quality of mussel farms in the Vigo estuary: pollution by PAHs, origin and effects on reproduction.", "content": "Environmental quality of mussel farms in the Vigo estuary: pollution by PAHs, origin and effects on reproduction. This work analyzes the influence of environmental and physiological parameters on PAHs accumulation in cultured mussels. Lipid content and reproductive stage are directly related with PAHs accumulation pattern. We observed a rapid accumulation and depuration of PAHs, mainly during periods of nutrients accumulation, spawns and gonadic restorations. Correlations between PAHs accumulation and physiological status indicate when mussels are more susceptible to adverse effects of these pollutants. A positive correlation between mutagenic congener's accumulation and occurrence of gonadic neoplastic disorders is shown for the first time in mussels. Molecular indices were used to identify the origin of hydrocarbons accumulated by Mytilus, showing a chronic pyrolytic pollution and pollutant episodes by petrogenic sources and biomass combustion in the studied area. Multivariate analysis suggests the possibility of including physiological parameters of sentinel organisms in environmental biomonitoring programs, mainly in aquaculture areas, taking into account their two aspects: farms productivity and human food safety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980085"}
{"pmid": "20980086", "title": "The physiological, transcriptional and genetic responses of an ozone-sensitive and an ozone tolerant poplar and selected extremes of their F2 progeny.", "content": "The physiological, transcriptional and genetic responses of an ozone-sensitive and an ozone tolerant poplar and selected extremes of their F2 progeny. Relatively little is known about the transcriptional response or genetic control of response and adaptation of trees to tropospheric ozone exposure. Such understanding is needed as up to 50% of forests, globally, may be subjected to phytotoxic concentrations of ozone. The physiological, transcriptional and genetic response to ozone was examined in Populus trichocarpa and P. deltoides, which show extreme sensitivity and tolerance to ozone, respectively. Using an inbred F2 mapping population derived from these two species, we mapped quantitative trait loci (QTL) for traits associated with ozone response, examined segregation of the transcriptional response to ozone and co-located genes showing divergent responses between tolerant and sensitive genotypes with QTL. QTL were identified linking detrimental effects of ozone with leaf and biomass traits and differential responses were found for key genes involved in ethylene production and response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980086"}
{"pmid": "20980088", "title": "Neighborhoods, daily activities, and measuring health risks experienced in urban environments.", "content": "Neighborhoods, daily activities, and measuring health risks experienced in urban environments. Studies of place and health often classify a subject's exposure status according to that which is present in their neighborhood of residence. One's neighborhood is often proxied by designating it to be an administratively defined unit such as census tract, to make analysis feasible. Although it is understood that residential space and actual lived space may not correspond and therefore exposure misclassification may result, few studies have the opportunity to investigate the implications of this issue concretely. A population-based case-control study that is currently underway provides one such opportunity. Adolescent victims of assault in Philadelphia, Pennsylvania, USA, and a control sample of adolescents drawn randomly from the community are being enrolled to study how alcohol consumption and time spent nearby alcohol outlets - individual-level and environmental-level risk factors for violence, respectively - over the course of daily activities relate to the likelihood of being assaulted. Data from a rapport-building exercise consist of hand-drawn sketches that subjects drew on street maps when asked to indicate the area considered their neighborhood. The main data consist of self-reported, detailed paths of the routes adolescents traveled from one location to the next over the course of one full day. Having noticed interesting patterns as the data collection phase proceeds, we present here an analysis conducted with the data of 55 control subjects between 15 and 19 years old. We found that hand-drawn neighborhoods and activity paths did not correspond to census tract boundaries, and time subjects spent in close proximity to alcohol outlets during their daily activities was not correlated with the prevalence of alcohol outlets in the census tract of their residence. This served as a useful example demonstrating how classifying subjects as exposed based solely on the prevalence of the exposure in the geographic area of their residence may misrepresent the exposure that is etiologically meaningful.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980088"}
{"pmid": "20980087", "title": "Infant mortality, season of birth and the health of older Puerto Rican adults.", "content": "Infant mortality, season of birth and the health of older Puerto Rican adults. The increasing prevalence of heart disease and diabetes among aging populations in low and middle income countries leads to questions regarding the degree to which endogenous early life exposures (exposures in utero) are important determinants of these health conditions. We devised a test using infant mortality (IMR) to verify if season of birth is a good indicator of early life (in utero) conditions that precipitate adult onset of disease. We linked annual IMR at the municipality (municipio) level from the late 1920s to early 1940s with individual birth year and place using a representative sample of older Puerto Rican adults (n = 1447) from the Puerto Rican Elderly: Health Conditions (PREHCO) study. We estimated the effects of season of birth on adult heart disease and diabetes for all respondents and then for respondents according to whether they were born when IMR was lower or higher, controlling for age, gender, obesity, respondent's educational level, adult behavior (smoking and exercise) and other early life exposures (childhood health, knee height and childhood socioeconomic status (SES)). The pattern of effects suggests that season of birth reflects endogenous causes: (1) odds of heart disease and diabetes were strong and significant for those born during the lean season in years when IMR was lower; (2) effects remained consistent even after controlling for other childhood conditions and adult behavior; but (3) no seasonality effects on adult health for adults born when IMR was higher. We conclude that in this population of older Puerto Rican adults there is continued support that the timing of adverse endogenous (in utero) conditions such as poor nutrition and infectious diseases is associated with adult heart disease and diabetes. It will be important to test the validity of these findings in other similar populations in the developing world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980087"}
{"pmid": "20980089", "title": "National female literacy, individual socio-economic status, and maternal health care use in sub-Saharan Africa.", "content": "National female literacy, individual socio-economic status, and maternal health care use in sub-Saharan Africa. The United Nations Millennium Development Goals have identified improving women's access to maternal health care as a key target in reducing maternal mortality in sub-Saharan Africa (sSA). Although individual factors such as income and urban residence can affect maternal health care use, little is known about national-level factors associated with use. Yet, such knowledge may highlight the importance of global and national policies in improving use. This study examines the importance of national female literacy on women's maternal health care use in continental sSA. Data that come from the 2002-2003 World Health Survey. Multilevel logistic regression was used to examine the association between national female literacy and individual's non-use of maternal health care, while adjusting for individual-level factors and national economic development. Analyses also assessed effect modification of the association between income and non-use by female literacy. Effect modification was evaluated with the likelihood ratio test (G(2)). We found that within countries, individual age, education, urban residence and household income were associated with lack of maternal health care. National female literacy modified the association of household income with lack of maternal health care use. The strength of the association between income and lack of maternal health care was weaker in countries with higher female literacy. We conclude therefore that higher national levels of female literacy may reduce income-related inequalities in use through a range of possible mechanisms, including women's increased labour participation and higher status in society. National policies that are able to address female literacy and women's status in sub-Saharan Africa may help reduce income-related inequalities in maternal health care use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980089"}
{"pmid": "20980090", "title": "Hierarchy of local structural and dynamics perturbations due to subdenaturing urea in the native state ensemble of DLC8 dimer.", "content": "Hierarchy of local structural and dynamics perturbations due to subdenaturing urea in the native state ensemble of DLC8 dimer. Local structural and dynamic modulations due to small environmental perturbations reflect the adaptability of the protein to different interactors. We have investigated here the preferential local perturbations in Dynein light chain protein (DLC8), a cargo adapter, by sub-denaturing urea concentrations. Equilibrium unfolding experiments by optical spectroscopic methods indicated a two state like unfolding of DLC8 dimer, with the transition mid-point occurring around 8.6M urea. NMR studies identified the β3 and β4 strands, N-, C- terminal regions, loops connecting β1 to α1, α1 to α2 and β3 to β4 as the soft targets of urea perturbation and thus indicated potential unfolding initiation sites. Native-state hydrogen exchange studies suggested the unfolding to traverse from the edges towards the centre of the secondary structural elements. At 6M urea the whole protein chain acts like a cooperative unit. These observations are expected to have important implications for the protein's multiple functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980090"}
{"pmid": "20980091", "title": "Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells.", "content": "Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells. Neuroblastoma is a malignant childhood tumour arising from precursor cells of the sympathetic nervous system. Genomic amplification of the MYCN oncogene is associated with dismal prognosis. For this group of high-risk tumours, the induction of tumour cell differentiation is part of current treatment protocols. MicroRNAs (miRNAs) are small non-coding RNA molecules that effectively reduce the translation of target mRNAs. MiRNAs play an important role in cell proliferation, apoptosis, differentiation and cancer. In this study, we investigated the role of N-myc on miRNA expression in MYCN-amplified neuroblastoma. We performed a miRNA profiling study on SK-N-BE (2) cells, and determined differentially expressed miRNAs during differentiation initiated by MYCN knockdown, using anti-MYCN short-hairpin RNA (shRNA) technology. Microarray analyses revealed 23 miRNAs differentially expressed during the MYCN knockdown-mediated neuronal differentiation of MNA neuroblastoma cells. The expression changes were bidirectional, with 11 and 12 miRNAs being up- and down-regulated, respectively. Among the down-regulated miRNAs, we found several members of the mir-17 family of miRNAs. Mir-21, an established oncomir in a variety of cancer types, became strongly up-regulated upon MYCN knockdown and the subsequent differentiation. Neither overexpression of mir-21 in the high-MYCN neuroblastoma cells, nor repression of increased mir-21 levels during MYCN knockdown-mediated differentiation had any significant effects on cell differentiation or proliferation. We describe a subset of miRNAs that were altered during the N-myc deprived differentiation of MYCN-amplified neuroblastoma cells. In this context, N-myc acts as both an activator and suppressor of miRNA expression. Mir-21 was up-regulated during cell differentiation, but inhibition of mir-21 did not prevent this process. We were unable to establish a role for this miRNA during differentiation and proliferation of the two neuroblastoma cell lines used in this study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980091"}
{"pmid": "20980093", "title": "Evaluating the PM damage cost due to urban air pollution and vehicle emissions in Seoul, Korea.", "content": "Evaluating the PM damage cost due to urban air pollution and vehicle emissions in Seoul, Korea. This study evaluated the prospective damage costs of PM(2.5) inhalation. We performed a health risk assessment based on an exposure-response function to estimate the annual population risk in the Seoul metropolitan city, Korea. Also, we estimated a willingness-to-pay (WTP) amount for reducing the mortality rate in order to evaluate a statistical life value. We combined the annual population risk and the value-of-statistical-life to calculate the damage cost estimate. In the health risk assessment, we applied the PM(2.5) relative risk to evaluate the annual population risk. We targeted an exposure population of 5,401,369 persons who were over the age of 30. Using a Monte-Carlo simulation for uncertainty analysis, we estimated that the population risk of PM(2.5) inhalation during a year in Seoul is 2181 premature deaths for acute exposure and 18,510 premature deaths for chronic exposure. The monthly average WTP for 5/1000 mortality reduction over ten years is $20.20 USD (95% C.I: $16.60-24.50) and the implied value-of-statistical-life (VSL) is $485,000 USD (95% C.I: $398,000-588,000). The damage cost estimate due to risk from PM(2.5) inhalation in Seoul is about $1057 million USD per year for acute exposure, and $8972 million USD per year for chronic exposure. It is important to note that this cost estimate does not reflect all health damage cost estimates in this urban area. This recommendation is a model for evaluating a mortality risk reduction and as such we must re-evaluate an integrated application of morbidity risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980093"}
{"pmid": "20980092", "title": "Sorption of hydrophobic pesticides on a Mediterranean soil affected by wastewater, dissolved organic matter and salts.", "content": "Sorption of hydrophobic pesticides on a Mediterranean soil affected by wastewater, dissolved organic matter and salts. Irrigation with treated wastewaters as an alternative in countries with severe water shortage may influence the sorption of pesticides and their environmental effects, as wastewater contains higher concentrations of suspended and dissolved organic matter and inorganic compounds than freshwater. We have examined the sorption behaviour of three highly hydrophobic pesticides (the herbicide pendimethalin and the insecticides α-cypermethrin and deltamethrin) on a Mediterranean agricultural soil using the batch equilibration method. We considered wastewater, extracts from urban sewage sludge with different dissolved organic carbon contents, and inorganic salt solutions, using Milli Q water as a control. All pesticides were strongly retained by soil although some sorption occurred on the walls of the laboratory containers, especially when wastewater and inorganic salt solutions were used. The calculation of distribution constants by measuring pesticide concentrations in soil and solution indicated that pendimethalin sorption was not affected whereas α-cypermethrin and deltamethrin retention were significantly enhanced (ca. 5 and 2 times, respectively) when wastewater or salt solutions were employed. We therefore conclude that the increased sorption of the two pesticides caused by wastewater cannot be only the result of its dissolved organic carbon content, but also of the simultaneous presence of inorganic salts in the solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980092"}
{"pmid": "20980094", "title": "Index models to evaluate the risk of phosphorus and nitrogen loss at catchment scales.", "content": "Index models to evaluate the risk of phosphorus and nitrogen loss at catchment scales. This paper investigates index models as a tool to estimate the risk of N and P source strengths and loss at the catchment scale. The index models assist managers in improving the focus of remediation actions that reduce nutrient delivery to waterbodies. N and P source risk factors (e.g. soil nutrient concentrations) and transport risk factors (e.g. distance-to-streams) are used to determine the overall risk of nutrient loss for a case study in the Tuross River catchment of coastal southeast Australia. In the development of the N index model for Tuross, particulate N was considered important based on the observed event water quality data. In contrast to previous N index models, erosion and contributing distance were therefore included in the Tuross River catchment N index. Event-based water quality monitoring, and soil information, or in data-poor catchments conceptual understanding, are essential to represent catchment-scale processes. The techniques have high applicability in other catchments, and are complementary to other modelling techniques such as process-based semi-distributed modelling. Index models generally provide much more detailed spatial resolution than fully- or semi-distributed conceptual modelling approaches. Semi-distributed models can be used to quantify nutrient loads and provide overall direction to set the broad focus of management. Index models can then be used to refine on-the-ground investigations and investment priorities. In this way semi-distributed models can be combined with index models to provide a set of powerful tools to influence management decisions and outcomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980094"}
{"pmid": "20980096", "title": "Re: Ricardo L. Favaretto, Shahrokh F. Shariat, Daher C. Chade, et al. The effect of tumor location on prognosis in patients treated with radical nephroureterectomy at Memorial Sloan-Kettering Cancer Center. Eur Urol 2010;58:574-580.", "content": "Re: Ricardo L. Favaretto, Shahrokh F. Shariat, Daher C. Chade, et al. The effect of tumor location on prognosis in patients treated with radical nephroureterectomy at Memorial Sloan-Kettering Cancer Center. Eur Urol 2010;58:574-580.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980096"}
{"pmid": "20980097", "title": "Ricardo L. Favaretto, Shahrokh F. Shariat, Daher C. Chade, et al. Comparison between laparoscopic and open radical nephroureterectomy in a contemporary group of patients: are recurrence and disease-specific survival associated with surgical technique? Eur Urol 2010;58:645-651.", "content": "Ricardo L. Favaretto, Shahrokh F. Shariat, Daher C. Chade, et al. Comparison between laparoscopic and open radical nephroureterectomy in a contemporary group of patients: are recurrence and disease-specific survival associated with surgical technique? Eur Urol 2010;58:645-651.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980097"}
{"pmid": "20980095", "title": "Prognostic impact of the 2009 UICC/AJCC TNM staging system for renal cell carcinoma with venous extension.", "content": "Prognostic impact of the 2009 UICC/AJCC TNM staging system for renal cell carcinoma with venous extension. The prognostic significance of venous involvement and tumour thrombus level in renal cell carcinoma (RCC) remains highly controversial. In 2010, the American Joint Committee on Cancer (AJCC) and the Union International Centre le Cancer (UICC) revised the RCC staging system (7th edition) based on tumour thrombus level, differentiating the T stage of tumours limited to renal-vein-only involvement. We aimed to evaluate the impact of tumour thrombus extension in a multi-institutional cohort of patients. An international consortium of 11 institutions was established to retrospectively review a combined cohort of 1215 patients undergoing radical nephrectomy and tumour thrombectomy for RCC, including 585 patients with inferior vena cava (IVC) involvement or higher. Predictive factors of survival, including histology, tumour thrombus level, nodal status, Fuhrman grade, and tumour size, were analysed. A total of 1122 patients with complete data were reviewed. The median follow-up for all patients was 24.7 mo, with a median survival of 33.8 mo. The 5-yr survival was 43.2% (renal vein involvement), 37% (IVC below the diaphragm), and 22% with caval involvement above the diaphragm. On multivariate analysis, tumour size (hazard ratio [HR]: 1.64 [range: 1.03-2.59]; p=0.036), Fuhrman grade (HR: 2.26 [range: 1.65-3.1]; p=0.000), nodal metastasis (HR: 1.32 [range: 1.09-1.67]; p=0.005), and tumour thrombus level (HR: 2.10 [range: 1.53-3.0]; p=0.00) correlated independently with survival. Based on analysis of the largest known cohort of patients with RCC along with IVC and atrial thrombus involvement, tumour thrombus level is an independent predictor of survival. Our findings support the changes to the latest AJCC/UICC staging system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980095"}
{"pmid": "20980098", "title": "Critical assessment of preoperative urinary prostate cancer antigen 3 on the accuracy of prostate cancer staging.", "content": "Critical assessment of preoperative urinary prostate cancer antigen 3 on the accuracy of prostate cancer staging. Knowledge about the staging significance of the prostate cancer antigen 3 (PCA3) score to better identify pathologic features after radical prostatectomy (RP) is limited and controversial. Our aim was to study the clinical staging significance of PCA3 to identify pathologic favorable and/or unfavorable features in the RP specimen. Complete retrospective clinical and pathologic data of consecutive men who had undergone RP from three tertiary referral centers including preoperative PCA3 scores (n=305) and computer-assisted planimetrically measured tumor volume data (n=160) were available. All patients were treated with RP. PCA3 scores were assessed using the PROGENSA assay (Gen-Probe, San Diego, CA, USA). Beyond standard risk factors (age, digital rectal examination, prostate-specific antigen, prostate volume, biopsy Gleason score, percentage of positive cores), five different PCA3 codings were used in logistic regression models to identify five distinct pathologic end points: (1) low-volume disease (<0.5 ml), (2) insignificant prostate cancer (PCa) according to the Epstein criteria, (3) extracapsular extension (ECE), (4) seminal vesicle invasion (SVI), and (5) aggressive disease defined as Gleason sum ≥7. Accuracy estimates of each end point were quantified using the area under the curve (AUC) of the receiver operator characteristic analysis in models with and without PCA3. PCA3 scores were significantly lower in low-volume disease and insignificant PCa (p ≤ 0.001). AUC of multivariable low-volume disease (+2.4 to +5.5%) and insignificant PCa models (+3 to +3.9%) increased when PCA3 was added to standard clinical risk factors. In contradistinction, regardless of its coding, PCA3 scores were not significantly elevated in pathologically confirmed ECE (p=0.4) or SVI (p=0.5), respectively. Higher PCA3 scores were associated with aggressive disease (p<0.001). Importantly, the addition of PCA3 to multivariable intermediate- and high-grade models did not improve prediction. Despite reporting the largest pathologic PCA3 study, the main limitation resides in its small sample size. PCA3 was confirmed as a valuable predictor of pathologically confirmed low-volume disease and insignificant PCa. Further exploration of its role as an additional marker to select patients for active surveillance may be warranted. In contradistinction, assessment of pathologically advanced or aggressive PCa is not improved using PCA3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980098"}
{"pmid": "20980099", "title": "ZEB1-responsive genes in non-small cell lung cancer.", "content": "ZEB1-responsive genes in non-small cell lung cancer. The epithelial to mesenchymal transition (EMT) is a developmental process enabling epithelial cells to gain a migratory mesenchymal phenotype. In cancer, this process contributes to metastases; however the regulatory signals and mechanistic details are not fully elucidated. Here, we sought to identify the subset of genes regulated in lung cancer by ZEB1, an E-box transcriptional repressor known to induce EMT. Using an Affymetrix-based expression database of 38 non-small cell lung cancer (NSCLC) cell lines, we identified 324 genes that correlated negatively with ZEB1 and 142 that were positively correlated. A mesenchymal gene pattern (low E-cadherin, high Vimentin or N-cadherin) was significantly associated with ZEB1 and ZEB2, but not with Snail, Slug, Twist1 or Twist2. Among eight genes selected for validation, seven were confirmed to correlate with ZEB1 by quantitative real-time RT-PCR in a series of 22 NSCLC cell lines, either negatively (CDS1, EpCAM, ESRP1, ESRP2, ST14) or positively (FGFR1, Vimentin). In addition, over-expression or knockdown of ZEB1 led to corresponding changes in gene expression, demonstrating that these genes are also regulated by ZEB1, either directly or indirectly. Of note, the combined knockdown of ZEB1 and ZEB2 led to apparent synergistic responses in gene expression. Furthermore, these responses were not restricted to artificial settings, since most genes were similarly regulated during a physiologic induction of EMT by TGF-β plus EGF. Finally, the absence of ST14 (matriptase) was linked to ZEB1 positivity in lung cancer tissue microarrays, implying that the regulation observed in vitro applies to the human disease. In summary, this study identifies a new set of ZEB-regulated genes in human lung cancer cells and supports the hypothesis that ZEB1 and ZEB2 are key regulators of the EMT process in this disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980099"}
{"pmid": "20980101", "title": "Granular activated carbon promoted ozonation of a food-processing secondary effluent.", "content": "Granular activated carbon promoted ozonation of a food-processing secondary effluent. This paper reports on the application of a simultaneous combination of ozone and a granular activated carbon (O(3)/GAC) as a tertiary treatment of a wastewater generated from the activity of various food-processing industries. Prior to the O(3)/GAC treatment, the wastewater was subjected to conventional primary and secondary treatments in a full-scale wastewater treatment plant (WWTP). The effluent from the WWTP presented high organic load (COD>500 mg/l and TOC>150 mg/l), which could be much reduced by the O(3)/GAC treatment. Results from the O(3)/GAC experiments were compared with those obtained in single ozonation, single adsorption onto GAC and sequential O(3)-GAC adsorption experiments. While single processes and the sequential one showed limited capacity to remove organic matter for the food-processing effluent (COD removal <40%), the simultaneous O(3)/GAC process led to decreases of COD up to 82% at the conditions here applied. The combined process also improved the ozone consumption, which decreased from about 19 g O(3)/g TOC (single ozonation process) to 8.2-10.7 g O(3)/g TOC (O(3)/GAC process). The reusability of the GAC throughout a series of consecutive O(3)/GAC experiments was studied with no apparent loss of activity for a neutral GAC (PZC = 6.7) but for a basic GAC (PZC = 9.1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980101"}
{"pmid": "20980100", "title": "Carbon nanotube composite coated platinum electrode for detection of Ga(III).", "content": "Carbon nanotube composite coated platinum electrode for detection of Ga(III). This study demonstrates the application of composite multi-walled carbon nanotube (MWCNT) polyvinylchloride (MWNT-PVC) based on 7-(2-hydroxy-5-methoxybenzyl)-5,6,7,8,9,10-hexahydro-2H benzo [b][1,4,7,10,13] dioxa triaza cyclopentadecine-3,11(4H,12H)-dione ionophore for gallium sensor. The sensor shows a good Nernstian slope of 19.68 ± 0.40 mV/decade in a wide linear range concentration of 7.9 × 10(-7) to 3.2 × 10(-2)M of Ga(NO(3))(3). The detection limit of this electrode is 5.2 × 10(-7)M of Ga(NO(3))(3). This proposed sensor is applicable in a pH range of 2.7-5.0. It has a short response time of about 10s and has a good selectivity over nineteen various metal ions. The practical analytical utility of this electrode is demonstrated by measurement of Ga(III) in river water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980100"}
{"pmid": "20980103", "title": "Sad mood increases pain sensitivity upon thermal grill illusion stimulation: implications for central pain processing.", "content": "Sad mood increases pain sensitivity upon thermal grill illusion stimulation: implications for central pain processing. In different fields of neuroscience research, illusions have successfully been used to unravel underlying mechanisms of stimulus processing. One such illusion existing for the field of pain research is the so-called thermal grill illusion. Here, painful sensations are elicited by interlacing warm and cold bars, with stimulus intensities (temperatures) of these bars being below the respective heat pain or cold pain thresholds. To date, the underlying mechanisms of this phenomenon are not completely understood. There is some agreement, however, that the sensation evoked by this stimulation is generated by central nervous interactions. Therefore, we followed two approaches in this study: firstly, we aimed at developing and validating a water-driven device which might be used in fMRI scanners in future studies - subject to minor adaptations. Secondly, we aimed to interfere with this illusion by induction of a sad mood state, a procedure which is suggested to influence central nervous structures that are also involved in pain processing. The newly developed device induced thermal grill sensations similar to those reported in the literature. Induction of sad, but not neutral mood states, resulted in higher pain and unpleasantness ratings of the painful illusion. These findings might be of importance for the understanding of pain processing in healthy volunteers, but putatively even more so in patients with major depressive disorder. Moreover, our results might indicate that central nervous structures involved in the affective domain or cognitive domain of pain processing might be involved in the perception of the illusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980103"}
{"pmid": "20980104", "title": "Veterinary parasitoses in the Mediterranean area.", "content": "Veterinary parasitoses in the Mediterranean area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980104"}
{"pmid": "20980102", "title": "RhoA/Rho kinase pathway contributes to the pathogenesis of thermal hyperalgesia in diabetic mice.", "content": "RhoA/Rho kinase pathway contributes to the pathogenesis of thermal hyperalgesia in diabetic mice. Diabetic neuropathy is one of the most common complications of diabetes and causes various problems in daily life. Several investigations have noted that many factors in the spinal cord are involved in the symptoms of painful diabetic neuropathy, and there are very few effective therapeutic regimens. In the present study, we sought to elucidate the role of the RhoA/Rho kinase (ROCK) pathway in thermal hyperalgesia in diabetic mice. The intracellular localization of RhoA and the expression of eNOS were measured by western blotting. Thermal hyperalgesia was assessed by the tail-flick test and mechanical allodynia was assessed by automated von Frey filament test in streptozotocin(STZ)-induced diabetic mice. The spinal cord of STZ-treated diabetic mice showed increased membrane-bound RhoA compared to non-diabetic control. Treatment with the RhoA inhibitor exoenzyme C3, Clostridium botulinum, and the ROCK inhibitor Y27632 attenuated thermal hyperalgesia and mechanical allodynia in diabetic mice. Moreover, daily treatment with simvastatin attenuated all of those changes in diabetic mice. The expression of eNOS and NO metabolite contents in the spinal cord was decreased in diabetic mice, and these changes were normalized by treatment with simvastatin. The present results show that HMG-CoA reductase inhibitors have an inhibitory effect on thermal hyperalgesia in diabetic mice, which is mediated by an increase in NO production through the inhibition of RhoA/ROCK pathways. These results suggest that ROCK inhibitors and HMG-CoA inhibitors may be attractive compounds to relieve the symptoms of painful diabetic neuropathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980102"}
{"pmid": "20980105", "title": "Will vitamin D supplementation ameliorate diseases characterized by chronic inflammation and fatigue?", "content": "Will vitamin D supplementation ameliorate diseases characterized by chronic inflammation and fatigue? Chronic NF-κB activation has been supposed as a key event in chronic fatigue syndrome (CFS) and many other better-defined pro-inflammatory diseases. Knowledge about the impact of deficiency vitamin D on chronic NF-κB activation could open a new disease approach. Whereas NF-κB activation leads at first to a pro-inflammatory immune response, later on a vitamin D-dependent anti-inflammatory response ensues. Binding of the active vitamin D metabolite 1,25(OH)(2)D(3) to vitamin D receptor (VDR) yields a transcription factor which represses NF-κB activation, and additionally modulates and down-regulates adaptive, but enhances innate immune responses, and improves redox balance, thus counterbalancing inflammation on multiple levels. However, this built-in late counterbalance against inflammation works only when stores of calcium and 25(OH)D(3) are abundant. Therefore a connection between lowered vitamin D-metabolism and persistent NF-κB activation, augmented nitrosative-oxidative stress, redox imbalance, chronic inflammation, and concomitant fatigue can be postulated. In order to confirm this hypothesis, randomized controlled clinical studies about the clinical effects of supplementation of calcium and vitamin D(3) would be necessary in diseases characterized by persistent NF-κB activation and chronic inflammation and fatigue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980105"}
{"pmid": "20980107", "title": "Clinical outcomes of definitive intensity-modulated radiation therapy with fluorodeoxyglucose-positron emission tomography simulation in patients with locally advanced cervical cancer. In regard to Kidd et al. (Int J Radiat Oncol Biol Phys 2010;77:1085-1091.).", "content": "Clinical outcomes of definitive intensity-modulated radiation therapy with fluorodeoxyglucose-positron emission tomography simulation in patients with locally advanced cervical cancer. In regard to Kidd et al. (Int J Radiat Oncol Biol Phys 2010;77:1085-1091.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980107"}
{"pmid": "20980109", "title": "Emergence and establishment of Usutu virus infection in wild and captive avian species in and around Zurich, Switzerland--genomic and pathologic comparison to other central European outbreaks.", "content": "Emergence and establishment of Usutu virus infection in wild and captive avian species in and around Zurich, Switzerland--genomic and pathologic comparison to other central European outbreaks. In late summer 2006 considerable mortality in wild and captive Passeriformes and Strigiformes was observed in Zurich, Switzerland. All animals were found in a range of 2 km(2). Observed clinical signs involved depression, ruffled plumage, incoordination, seizures and peracute death. Nutritional status was generally moderate to poor in wild birds, and variable in captive animals. Necropsy showed marked splenomegaly, a mild hepatomegaly, and pulmonary hyperemia in most animals. Histopathologic lesions were very discrete and consisted mainly of neuronal necrosis, leucocytolysis in and around the brain blood vessels, and miliary liver necrosis. The diagnosis Usutu virus (USUV) infection was established by USUV-specific immunohistochemistry and reverse transcription-polymerase chain reaction. Partial nucleotide sequence comparisons revealed>99% identity between the viruses that emerged in Zurich in 2006, in Vienna in 2001, and in Budapest in 2005. Since 2008 a significantly lower mortality was observed in wild Passeriformes, but USUV infection was confirmed for the first time beyond Zurich city limits. Indoor housing and regular treatment against ectoparasites are likely to have prevented acute USUV disease in captive Strigiformes. USUV is a mosquito-borne flavivirus causing fatalities in various avian species. After the initial European outbreaks in Austria in 2001 it appears that the virus has extended its range in Central Europe and has established a transmission cycle between local bird and mosquito species. Further episodes of increased avian mortality in the forthcoming years, with impact on wild and captive bird populations, predominantly Passeriformes and Strigiformes, can be anticipated. Furthermore, the possibility of broader dispersal of USUV in Europe during the next mosquito seasons must be considered and an increased mortality in Passeriformes and Strigiformes must be expected until protective \"flock immunity\" is established. Collections of valuable and endangered Passeriformes and Strigiformes, especially young of the year, should therefore be housed indoors or treated against ectoparasites at acceptable intervals between July and September each year.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980109"}
{"pmid": "20980108", "title": "Higher biologically effective dose of radiotherapy is associated with improved outcomes for locally advanced non-small cell lung carcinoma treated with chemoradiation: an analysis of the Radiation Therapy Oncology Group.", "content": "Higher biologically effective dose of radiotherapy is associated with improved outcomes for locally advanced non-small cell lung carcinoma treated with chemoradiation: an analysis of the Radiation Therapy Oncology Group. Patients treated with chemoradiotherapy for locally advanced non-small-cell lung carcinoma (LA-NSCLC) were analyzed for local-regional failure (LRF) and overall survival (OS) with respect to radiotherapy dose intensity. This study combined data from seven Radiation Therapy Oncology Group (RTOG) trials in which chemoradiotherapy was used for LA-NSCLC: RTOG 88-08 (chemoradiation arm only), 90-15, 91-06, 92-04, 93-09 (nonoperative arm only), 94-10, and 98-01. The radiotherapeutic biologically effective dose (BED) received by each individual patient was calculated, as was the overall treatment time-adjusted BED (tBED) using standard formulae. Heterogeneity testing was done with chi-squared statistics, and weighted pooled hazard ratio estimates were used. Cox and Fine and Gray's proportional hazard models were used for OS and LRF, respectively, to test the associations between BED and tBED adjusted for other covariates. A total of 1,356 patients were analyzed for BED (1,348 for tBED). The 2-year and 5-year OS rates were 38% and 15%, respectively. The 2-year and 5-year LRF rates were 46% and 52%, respectively. The BED (and tBED) were highly significantly associated with both OS and LRF, with or without adjustment for other covariates on multivariate analysis (p < 0.0001). A 1-Gy BED increase in radiotherapy dose intensity was statistically significantly associated with approximately 4% relative improvement in survival; this is another way of expressing the finding that the pool-adjusted hazard ratio for survival as a function of BED was 0.96. Similarly, a 1-Gy tBED increase in radiotherapy dose intensity was statistically significantly associated with approximately 3% relative improvement in local-regional control; this is another way of expressing the finding that the pool-adjusted hazard ratio as a function of tBED was 0.97. Higher radiotherapy dose intensity is associated with improved local-regional control and survival in the setting of chemoradiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980108"}
{"pmid": "20980110", "title": "Fingermark detection on non-porous and semi-porous surfaces using NaYF4:Er,Yb up-converter particles.", "content": "Fingermark detection on non-porous and semi-porous surfaces using NaYF4:Er,Yb up-converter particles. This article describes the first use of an anti-Stokes material, or up-converter, for the development of latent fingermarks on a range of non-porous surfaces. Anti-Stokes materials can absorb long-wavelength light and emit light at a shorter wavelength. This property is unusual in both natural and artificial materials and so fingermark detection techniques based on anti-Stokes luminescence are potentially sensitive and selective. Latent fingermarks on luminescent and non-luminescent substrates, including Australian polymer banknotes (a well-known 'difficult' surface), were developed with sodium yttrium tetrafluoride doped with erbium and ytterbium (NaYF(4):Er,Yb) by dry powder, wet powder, and cyanoacrylate staining techniques. This study illustrates the potential of up-converter phosphors for the detection of latent fingermarks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980110"}
{"pmid": "20980112", "title": "A surgical technique for size reduction of exceedingly large tracheal stoma.", "content": "A surgical technique for size reduction of exceedingly large tracheal stoma. After tracheostomy some patients may develop a tracheal stoma of excessive size. Effective application of tracheostomy tube is not possible in those patients. Inserted cannula for protection from aspiration or artificial ventilatory assistance becomes easily displaced in two patients with tracheal stoma of excessive size. A simple surgical technique for treatment of large symptomatic tracheal stoma is described in the present study. A complete symptomatic improvement was noted in those patients after size reduction of the stoma using a new surgical technique. Surgical size reduction could be helpful in large tracheal stoma in which tracheal tubes could not be secured from dislocation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980112"}
{"pmid": "20980111", "title": "Mandible preserving pull-through oropharyngectomy for advanced oropharyngeal cancer: a pilot study.", "content": "Mandible preserving pull-through oropharyngectomy for advanced oropharyngeal cancer: a pilot study. Through our experiences in the parapharyngeal space (PPS) surgery, we have learned that it is possible to gain wide exposure of the PPS near to the skull base with a transcervical approach alone. Thus, we presumed that if this type of transcervical approach would be combined with a transoral approach, a less invasive oropharyngectomy without mandibulotomy and lip-splitting might be feasible for the resection of advanced oropharyngeal cancer, sparing the morbidities associated with conventional mandibular swing approach or its modified procedures. We termed this method as a mandible preserving pull-through oropharyngectomy (MPPO) and evaluated its feasibility and efficacy in this pilot study. MPPO was applied for a series of 7 patients with advanced lateral and/or upper oropharyngeal cancer including 2 patients with T4 stage. Our current application of MPPO excludes tumors, which involves mandibular bone, the higher part of the medial pterygoid muscle, and the lateral pterygoid muscle. Safe and sufficient excision of tumors was feasible by MPPO avoiding morbidities associated with mandibulotomy or lip-splitting without compromising oncological outcomes. Although preliminary, our favorable outcomes indicate that MPPO might be a useful alternative to conventional mandibular swing approach or its modified procedures for selected cases with advanced oropharyngeal cancer. Further accumulation of data is encouraged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980111"}
{"pmid": "20980113", "title": "Risk factors of thyroid tumors: role of environmental and occupational exposures to chemical pollutants.", "content": "Risk factors of thyroid tumors: role of environmental and occupational exposures to chemical pollutants. The rising incidence of thyroid cancer observed during the last few decades in most western countries is explained in large part by increasing numbers of diagnoses due to changes in medical screening practices. However, beside radiation exposure, exposure to environmental chemicals may also play a role in thyroid cancer etiology and in the increased incidence. This paper presents the main chemicals suspected to induce thyroid tumorigenesis, and epidemiological results on the association between chemical exposure and thyroid tumors. We reviewed experimental studies to identify the main chemicals possibly involved in thyroid tumorigenesis. We also reviewed the main epidemiological studies investigating the association between environmental chemical exposure and thyroid neoplasm in humans. Environmentally abundant chemicals may disrupt thyroid function and/or play a role in tumorigenesis through a variety of mechanisms. Epidemiological results provide insufficient evidence of a causal link between exposure to environmental chemicals and thyroid tumors, but raise the hypothesis of an increased risk of thyroid neoplasm for workers in the leather, wood, and paper industries, and those exposed to certain solvents and pesticides. This paper highlights the need for large epidemiological studies evaluating the exposure to various groups of environmental chemicals and its impact on the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980113"}
{"pmid": "20980114", "title": "Polycythemia and elevated serum erythropoietin associated with a liver haemangioma.", "content": "Polycythemia and elevated serum erythropoietin associated with a liver haemangioma. Secondary polycythemia is a rare condition, which is usually associated to neoplasia or chronic pulmonary disorders. A 41-year-old man man with no history of liver disease was admitted for erythrocytosis. The paraclinical investigations revealed an increased erythropoietin level in the serum and a voluminous hepatic tumor but its identification was unclear. A liver resection was performed and the histopathological examination concluded that the tumor was a giant cavernous haemangioma with extensive myxoid changes. After surgical resection of the haemangioma, normal haemoglobin and serum erythropoietin were obtained without any further treatment. Liver haemangioma must be included in rare cause of secondary polycythemia, and surgical resection of the haemangioma should be considered as the standard to induce complete remission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980114"}
{"pmid": "20980115", "title": "Cardiac magnetic resonance imaging: infarct size is an independent predictor of mortality in patients with coronary artery disease.", "content": "Cardiac magnetic resonance imaging: infarct size is an independent predictor of mortality in patients with coronary artery disease. Cardiac magnetic resonance imaging (CMR) can accurately determine infarct size. Prior studies using indirect methods to assess infarct size have shown that patients with larger myocardial infarctions have a worse prognosis than those with smaller myocardial infarctions. This study assessed the prognostic significance of infarct size determined by CMR. Cine and contrast CMR were performed in 100 patients with coronary artery disease (CAD) undergoing routine cardiac evaluation. Infarct size was determined by planimetry. We used Cox proportional hazards regression analyses (stepwise forward selection approach) to evaluate the risk of all-cause death associated with traditional cardiovascular risk factors, symptoms of heart failure, medication use, left ventricular ejection fraction, left ventricular mass, angiographic severity of CAD and extent of infarct size determined by CMR. Ninety-one patients had evidence of myocardial infarction by CMR. Mean follow-up was 4.8±1.6 years after CMR, during which time 30 patients died. The significant multivariable predictors of all-cause mortality were extent of myocardial infarction by CMR, extent of left ventricular systolic dysfunction, symptoms of heart failure, and diabetes mellitus (P<.05). The presence of infarct greater than or equal to 24% of left ventricular mass and left ventricular ejection fraction less than or equal to 30% were the most optimal cut-off points for the prediction of death with bivariate adjusted hazard ratios of 2.11 (95% confidence interval 1.02-4.38) and 4.06 (95% confidence interval 1.73-9.54), respectively. The extent of myocardial infarction determined by CMR is an independent predictor of death in patients with CAD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980115"}
{"pmid": "20980116", "title": "Efficient large-array k-domain parallel MRI using channel-by-channel array reduction.", "content": "Efficient large-array k-domain parallel MRI using channel-by-channel array reduction. This article presents a method to explore the flexibility of channel reduction in k-domain parallel imaging (PI) with massive arrays to improve the computation efficiency. In PI, computation cost increases with the number of channels. For the k-domain methods requiring channel-by-channel reconstruction, this increase can be significant with massive arrays. In this article, a method for efficient k-domain PI reconstruction in large array systems is proposed. The method is based on the fact that in large arrays the channel sensitivity is localized, which allows channel reduction through channel cross correlation. The method is tested with simulated and in vivo MRI data from a 32-channel and 64-channel systems using the multicolumn multiline interpolation (MCMLI) method. Results show that the proposed algorithm can achieve similar or improved reconstruction quality with significantly reduced computation time for massive arrays with localized sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980116"}
{"pmid": "20980117", "title": "Assessment of metabolic changes in the striatum of a MPTP-intoxicated canine model: in vivo ¹H-MRS study of an animal model for Parkinson's disease.", "content": "Assessment of metabolic changes in the striatum of a MPTP-intoxicated canine model: in vivo ¹H-MRS study of an animal model for Parkinson's disease. Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive loss of the dopaminergic neurons in the substantia nigra pars compacta, which projects to the striatum. We induced a selective loss of nigrostriatal dopamine neurons, by infusing the mitochondrial complex 1 inhibitor 1-methyl 4-phenyl 1,2,3,6-tetrahydropyridine (MPTP) into adult beagle dogs (N=5). Single voxel ¹H water suppressed magnetic resonance spectroscopy (¹H-MRS) at 3 T was used to assess the metabolic changes in the striatum of canine before and after MPTP intoxication. The metabolite spectra obtained from the striatum (voxel size: 2 cm³) showed a lower N-acetyl aspartate to total creatine (creatine+phosphocreatine) ratio after MPTP intoxication. There were no significant differences in other metabolite ratios such as glutamate+glutamine, choline-containing compounds (glycerophosphocholine+phophorylcholine and myo-inositol). Our findings indicated that ¹H-MRS is a sensitive, noninvasive measure of neural toxicity and biochemical alterations of the striatum in a canine model of PD, and further studies are needed to confirm brain metabolic changes in association with progression of MPTP-intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980117"}
{"pmid": "20980119", "title": "Management of childhood intussusception after reduction by enema.", "content": "Management of childhood intussusception after reduction by enema. The objective of the study was to describe the utility of emergency department (ED)/outpatient management after enema reduction for childhood intussusception. A retrospective medical record review of children aged 2 months to 6 years with confirmed intussusception who underwent enema reduction in a tertiary care academic children's hospital was performed. Subjects were analyzed with respect to location of care after reduction (ED/outpatient vs inpatient) and number, timing, and outcome of recurrences. One hundred seventeen patients were diagnosed with intussusception by contrast or air enema during the 15-year study period, and 56 fulfilled our inclusion criteria. Ten patients (18%) were admitted to hospital after enema reduction. Mean length of stay was 33.7 hours in the hospitalized group and 7 hours in the ED group. Seven of the 56 patients had recurrences (12.5% recurrence rate). Two recurred while being observed in the ED (at 30 minutes and at 2 hours after reduction), 2 recurred at home (at 10 and 28 hours after reduction), and the other 3 recurred several months later. The early recurrence rate (recurring within 24 hours) was 5.3%. No patient had an adverse event (perforation, sepsis, bowel resection). Outpatient management is used for the majority of patients with intussusception at our institution after enema reduction. The early recurrence rate is low, and patients with recurrence after discharge do well without adverse outcomes. Emergency department observation of patients after enema reduction appears to be safe and should be routine for uncomplicated cases of intussusception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980119"}
{"pmid": "20980118", "title": "An HPLC-MS/MS method for the quantitative determination of 4-hydroxy-anethole trithione in human plasma and its application to a pharmacokinetic study.", "content": "An HPLC-MS/MS method for the quantitative determination of 4-hydroxy-anethole trithione in human plasma and its application to a pharmacokinetic study. A selective, rapid and sensitive method for the quantitation of 4-hydroxy-anethole trithione (ATX) in human plasma based on high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was developed and validated. Paracetamol was used as the internal standard (I.S.). After liquid-liquid extraction of 500 μL plasma with ethyl acetate, ATX and the I.S. were chromatographed on an Inertsil(®) ODS-3 column. The mobile phase was consisted of methanol-water (75:25, v/v) with a flow rate of 0.25 mL/min. The detection was performed on a triple quadrupole tandem mass spectrometer by multiple reaction monitoring (MRM) mode via electrospray ionization (ESI) source. The calibration curve was linear over the range of 0.452-603 ng/mL (r(2)≥0.99) with a lower limit of quantitation (LLOQ) of 0.452 ng/mL. The intra- and inter-day precision (relative standard deviation, R.S.D.) values were below 13% and the accuracy (relative error, R.E.) was from -2.7% to -7.5% at three quality control levels. The assay herein described was successfully applied to a pharmacokinetic study of anethole trithione (ATT) tablet in healthy volunteers after oral administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980118"}
{"pmid": "20980120", "title": "Neurologic complication after a roller coaster ride.", "content": "Neurologic complication after a roller coaster ride. Neurologic complications after roller coaster rides are uncommon but potentially catastrophic. Physicians should have a high index of suspicion and prompt appropriate investigation. A 22-year-old healthy African American man presented with a 2-day history of constant occipital headache associated with vertigo, nausea, vomiting, and ambulatory dysfunction. Physical examination showed gait ataxia, slight dysmetria, and vertical nystagmus. Magnetic resonance imaging (MRI) of the brain showed early subacute ischemic infarct in the right cerebellum in the distribution of the right posterior inferior cerebellar artery. Magnetic resonance angiography of the neck showed focal dissection of the right vertebral artery at C1 through C2 level. On subsequent questioning, the patient recollected riding a roller coaster 2 weeks before the onset of symptoms. Anticoagulation with heparin was started, and the patient was bridged to oral warfarin. After a 5-day uneventful hospital course, symptoms improved and patient was discharged on oral anticoagulation. Cervicocephalic arterial dissections after roller coaster rides are rarely described in literature. The acceleration and abrupt changes of direction might lead to indirect trauma that is applied to mobile portions of the cervicocephalic arteries leading to intimal tears. Magnetic resonance angiography combined with axial T1-weighted cervical MRI is preferred because it is a high-sensitive, noninvasive test. The rationale for the use of anticoagulants or antiplatelets in patients with cervicocephalic arterial dissection is to prevent early recurrence and infarction. However, a meta-analysis failed to show significant difference in the rates of disability or death between both groups. Therefore, the decision for medical treatment should be made in a case-by-case basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980120"}
{"pmid": "20980125", "title": "Core biopsy of the breast lesions: review of technical problems and solutions: a pictorial review.", "content": "Core biopsy of the breast lesions: review of technical problems and solutions: a pictorial review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980125"}
{"pmid": "20980126", "title": "The contribution of attentional bias to worry: distinguishing the roles of selective engagement and disengagement.", "content": "The contribution of attentional bias to worry: distinguishing the roles of selective engagement and disengagement. This study investigated the effect on worry of biased attentional engagement and disengagement. Variants of a novel attention modification paradigm were developed, designed to induce a group difference either in participants' tendency to selectively engage with, or disengage from, threatening meanings. An index of threat bias, reflecting relative speeding to process threat word compared to non-threat word content, confirmed that both procedures were effective in inducing differential attentional bias. Importantly, when the induced group difference in attentional bias followed the procedure designed to influence selective engagement with threat meanings, it also gave rise to a corresponding group difference in worry. This was not the case when it was induced by the procedure designed to influence selective disengagement from threat meanings. These findings suggest that facilitated attentional engagement with threat meanings may causally contribute to variability in worry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980126"}
{"pmid": "20980127", "title": "The impact of compulsive cleaning on confidence in memory and cleanliness.", "content": "The impact of compulsive cleaning on confidence in memory and cleanliness. Recent research has helped elucidate a potentially important mechanism by which repetitive, compulsive behavior leads to memory and perceptual distrust. Although the effects of repeated checking and perseverative staring have been investigated, no research to date has examined the impact of compulsive cleaning on cognitive confidence. This study examined the effect of repeated cleaning in a cohort of 60 non-clinical participants. Two sets of items were used--three different colored bowls, and three different colored plates. Participants either repeatedly cleaned bowls or plates, with the other set serving as a control. A range of variables was also assessed at pre-test and post-test, including the accuracy of memory for which items were cleaned, as well as confidence in memory, and confidence that the items were clean. Results demonstrated that while there was no impact on memory accuracy, participant's memory confidence for the control items improved, while memory confidence for the repeatedly cleaned items did not. There was also no impact of repeated cleaning on confidence in cleanliness of repeatedly cleaned or control items. Results expand on previous research examining repeated behavior and metacognition, and provide initial insights into differences between repeated checking and cleaning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980127"}
{"pmid": "20980128", "title": "A better view of the temporomandibular joint: a technical note.", "content": "A better view of the temporomandibular joint: a technical note. The authors present a method of gaining access to the temporomandibular joint that improves visibility and surgical access. It should reduce operating times and improve results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980128"}
{"pmid": "20980130", "title": "Mitochondrial DNA (mtDNA) and schizophrenia.", "content": "Mitochondrial DNA (mtDNA) and schizophrenia. The poorly understood aetiology of schizophrenia is known to involve a major genetic contribution even though the genetic factors remain elusive. Most genetic studies are based on Mendelian rules and focus on the nuclear genome, but current studies indicate that other genetic mechanisms are probably involved. This review focuses on mitochondrial DNA (mtDNA), a maternally inherited, 16.6-Kb molecule crucial for energy production that is implicated in numerous human traits and disorders. The aim of this review is to summarise the studies that have explored mtDNA in schizophrenia patients and those which provide evidence for its implication in this illness. Alterations in mitochondrial morphometry, brain energy metabolism, and enzymatic activity in the mitochondrial respiratory chain suggest a mitochondrial dysfunction in schizophrenia that could be related to the genetic characteristics of mtDNA. Moreover, evidence of maternal inheritance and the presence of schizophrenia symptoms in patients suffering from a mitochondrial disorder related to an mtDNA mutation suggest that mtDNA is involved in schizophrenia. The association of specific variants has been reported at the molecular level; however, additional studies are needed to determine whether the mitochondrial genome is involved in schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980130"}
{"pmid": "20980129", "title": "Evaluation of the quality of life of patients with maxillofacial defects after prosthodontic therapy with obturator prostheses.", "content": "Evaluation of the quality of life of patients with maxillofacial defects after prosthodontic therapy with obturator prostheses. The purpose of this study was to investigate how patients with maxillofacial defects evaluate their quality of life after maxillectomy and prosthodontic therapy with obturator prostheses. 43 patients were included in the study (25 female, 18 male). 31 (72%) patients completed a standardized questionnaire of 143 items and then answered additional questions in a standardized interview. Global quality of life after prosthodontic therapy with obturator prostheses was 64% (±22.9) on average. Functioning of the obturator prosthesis, impairment of ingestion, speech and appearance, the extent of therapy, and the existence of pain had significant impact on the quality of life (p<0.005). Orofacial rehabilitation of patients with maxillofacial defects using obturator prostheses is an appropriate treatment modality. To improve the situation of patients prior to and after maxillectomy sufficient information about the treatment, adequate psychological care and speech therapy should be provided.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980129"}
{"pmid": "20980131", "title": "In situ green synthesis of biocompatible ginseng capped gold nanoparticles with remarkable stability.", "content": "In situ green synthesis of biocompatible ginseng capped gold nanoparticles with remarkable stability. We report herein an unprecedented one-step green synthesis of gold nanoparticles (G-AuNps), using naturally occurring Korean red ginseng root (Panax ginseng C.A. Meyer) without any special reducing/capping agents. The AuNps generated through this ginseng-mediated process did not aggregate suggesting that the phytochemicals present in them serve as excellent coatings on the nanoparticles and thus, provide robust shielding from aggregations. The ginseng-generated AuNps exhibit remarkable in vitro stability in various buffers including: cysteine, histidine, saline, sodium chloride and a host of pH ranges. Furthermore, the phytochemical coatings on the G-AuNps rendered them nontoxic as demonstrated through detailed cytotoxicity assays using WST-8 counting kit, performed on normal cervical cells lines. The present study opens up a new possibility of conveniently synthesizing AuNps using natural products which will be useful in optoelectronic and biomedical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980131"}
{"pmid": "20980132", "title": "Thermoresponsive poly(N-isopropyl acrylamide)-grafted polycaprolactone films with surface immobilization of collagen.", "content": "Thermoresponsive poly(N-isopropyl acrylamide)-grafted polycaprolactone films with surface immobilization of collagen. Thermoresponsive poly(N-isopropylacrylamide) (P(NIPAAm))-grafted polycaprolactone (PCL) films with a suitable amount of immobilized cell-adhesive collagen were prepared to improve cell adhesion and proliferation above the lower critical solution temperature (LCST, 32°C) of P(NIPAAm) without destroying cell detachment properties at lower temperatures. Covalently tethered P(NIPAAm) brushes on PCL film surfaces were first prepared via surface-initiated atom transfer radical polymerization (ATRP). The alkyl bromide end groups of the grafted P(NIPAAm) brushes were used in nucleophilic substitution reactions for the direct coupling of collagen to produce the collagen-immobilized thermoresponsive PCL surface. At 37°C, the cell attachments on the collagen-immobilized thermoresponsive PCL surface were enhanced substantially. The attached cells could be recovered simply by lowering culture temperature. The P(NIPAAm)-grafted PCL films with immobilized collagen are potentially useful as adhesion modifiers for advanced cell culture and tissue engineering applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980132"}
{"pmid": "20980133", "title": "Effect of the two new calcium channel blockers mebudipine and dibudipine on vascular flow of isolated kidney of normal and diabetic rats.", "content": "Effect of the two new calcium channel blockers mebudipine and dibudipine on vascular flow of isolated kidney of normal and diabetic rats. Calcium channel blockers (CCBs) are powerful drugs in the treatment of hypertension. These agents also preserve or improve renal function in patients with essential hypertensive renal disease or diabetic renal disease. There is increasing experimental evidence for the beneficial effects of dihydropyridine-type CCBs. In previous researches mebudipine and dibudipine two newly synthesized CCBs, improved normal rat kidney perfusion. The study was designed to investigate the effects of these new drugs on vascular flow of isolated kidney from diabetic rats comparing to nifedipine, also to test that the effects of the new DHPs and nifedipine on renal blood flow in the isolated perfused kidney might be altered in experimental diabetic rats. In this study normal and STZ-induced 6- to 7-week diabetic rats were used. Following the establishment of renal perfusion with a constant baseline pressure of 85-95mmHg, the renal vasculature was constricted by phenylephrine (PE) injection. Changes in the baseline perfusion pressure were recorded. Then DHP CCBs prepared in perfusion medium was fed to the kidney for 30min. Finally alterations in the baseline pressure arising from PE administrations in the presence of DHPs were recorded and data analyses were done. Mebudipine and dibudipine (1-10μM) were more effective in the inhibition of phenylephrine (PE)-induced perfusion pressure in isolated kidney of diabetic rats compared to nifedipine at similar concentrations. Based on the obtained EC(50) values for DHPs-induced inhibition of prefusion pressure, it is referred that lower concentrations of mebudipine and dibudipine are needed to inhibit PE-evoked increments of renal perfusion pressure in diabetic rats. Mebudipine and dibudipine have more potency in inhibiting PE-elicited perfusion pressure in isolated kidney from diabetic rats compared to normal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980133"}
{"pmid": "20980134", "title": "Electrocardiogram analysis using a combination of statistical, geometric, and nonlinear heart rate variability features.", "content": "Electrocardiogram analysis using a combination of statistical, geometric, and nonlinear heart rate variability features. The paper addresses a common and recurring problem of electrocardiogram (ECG) classification based on heart rate variability (HRV) analysis. Current understanding of the limits of HRV analysis in diagnosing different cardiac conditions is not complete. Existing research suggests that a combination of carefully selected linear and nonlinear HRV features should significantly improve the accuracy for both binary and multiclass classification problems. The primary goal of this work is to evaluate a proposed combination of HRV features. Other explored objectives are the comparison of different machine learning algorithms in the HRV analysis and the inspection of the most suitable period T between two consecutively analyzed R-R intervals for nonlinear features. We extracted 11 features from 5min of R-R interval recordings: SDNN, RMSSD, pNN20, HRV triangular index (HTI), spatial filling index (SFI), correlation dimension, central tendency measure (CTM), and four approximate entropy features (ApEn1-ApEn4). Analyzed heart conditions included normal heart rhythm, arrhythmia (any), supraventricular arrhythmia, and congestive heart failure. One hundred patient records from six online databases were analyzed, 25 for each condition. Feature vectors were extracted by a platform designed for this purpose, named ECG Chaos Extractor. The vectors were then analyzed by seven clustering and classification algorithms in the Weka system: K-means, expectation maximization (EM), C4.5 decision tree, Bayesian network, artificial neural network (ANN), support vector machines (SVM) and random forest (RF). Four-class and two-class (normal vs. abnormal) classification was performed. Relevance of particular features was evaluated using 1-Rule and C4.5 decision tree in the cases of individual features classification and classification with features' pairs. Average total classification accuracy obtained for top three classification methods in the two classes' case was: RF 99.7%, ANN 99.1%, SVM 98.9%. In the four classes' case the best results were: RF 99.6%, Bayesian network 99.4%, SVM 98.4%. The best overall method was RF. C4.5 decision tree was successful in the construction of useful classification rules for the two classes' case. EM and K-means showed comparable clustering results: around 50% for the four classes' case and around 75% for the two classes' case. HTI, pNN20, RMSSD, ApEn3, ApEn4 and SFI were shown to be the most relevant features. HTI in particular appears in most of the top-ranked pairs of features and is the best analyzed feature. The choice of the period T for nonlinear features was shown to be arbitrary. However, a combination of five different periods significantly improved classification accuracy, from 70% for a single period up to 99% for five periods. Analysis shows that the proposed combination of 11 linear and nonlinear HRV features gives high classification accuracy when nonlinear features are extracted for five periods. The features' combination was thoroughly analyzed using several machine learning algorithms. In particular, RF algorithm proved to be highly efficient and accurate in both binary and multiclass classification of HRV records. Interpretable and useful rules were obtained with C4.5 decision tree. Further work in this area should elucidate which features should be extracted for the best classification results for specific types of cardiac disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980134"}
{"pmid": "20980135", "title": "Searching for optimal dose-volume constraints to reduce rectal toxicity after hypofractionated radiotherapy for prostate cancer.", "content": "Searching for optimal dose-volume constraints to reduce rectal toxicity after hypofractionated radiotherapy for prostate cancer. Late rectal toxicity is a major concern for prostate cancer patients treated with radiotherapy. Rectal dose-volume constraints, set as guidelines to reduce its incidence, vary among institutions. From a group of patients uniformly treated with hypofractionated radiotherapy, we correlated the incidence of late rectal toxicity with rectal dose-volume rectal constraints as described in three randomised trials for prostate cancer. Favourable-risk prostate cancer patients received a dose of 66 Gy in 22 fractions without hormonal therapy. Toxicity was prospectively assessed using Common Toxicity Criteria v3. The whole or part of the rectum and rectal wall were contoured as an organ at risk for all patients. The rectal constraints of the RTOG 0126, RTOG 0415 and the PROFIT trials were used to correlate with late rectal toxicity. The median follow-up time was 58 months. Late rectal toxicity was 62, 20 and 18% for grades 0, 1 and 2/3, respectively. No statistically significant correlation was found between late rectal toxicity and the rectal constraints used in the three trials. The number of patients violating the recommended constraints was similar for the group with grade 2/3 toxicity and the group without any toxicity. Analysis derived from the actual dose-volume histogram dose parameters of this group of patients did not show a relationship between dose to volume of the rectum and late rectal toxicity that could generate a guideline of dose constraints. For this group of patients, despite the use of recognised dose-volume constraint guidelines of three trials, we were unable to establish a relationship between these constraints and the late rectal toxicity registered. Further studies on the correlation of dosimetric parameters with rectal toxicity, particularly for hypofractionated regimens, are required. Non-dosimetric factors may also be involved in the risk of late rectal toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980135"}
{"pmid": "20980136", "title": "Residual postoperative tumour volume predicts outcome after high-dose radiotherapy for chordoma and chondrosarcoma of the skull base and spine.", "content": "Residual postoperative tumour volume predicts outcome after high-dose radiotherapy for chordoma and chondrosarcoma of the skull base and spine. High-dose radiotherapy after surgical debulking is the treatment of choice for chordomas and chondrosarcomas. This study reviewed our outcomes, in relation to residual tumour volume and radiation dose, in order to inform our future practice. Nineteen patients referred to the Neuro-Oncology Unit at Addenbrooke's Hospital (Cambridge, UK) between 1996 and 2009 and treated with photon radiotherapy were reviewed. Seventeen of the 19 were treated with curative intent. The median follow-up was 53 months. The tumours in the study had a mean gross tumour volume (GTV) of 17.2 cm(3) (median 10.5 cm(3)) and a range of 0-76.3 cm(3). The median dose was 65Gy in 39 fractions. The 5 year cause-specific survival for radically treated patients with chordomas was 92% and the 5 year local control rate was 83%. The 5 year cause-specific survival and local control rates with chondrosarcomas were both 100%. A planning target volume (PTV) below 90 cm(3) is predictive of local control, but volumes above this are not. The GTV seems to be a better predictor of outcome: among the 17 of 19 patients treated curatively, a GTV threshold of 30 cm(3) distinguished local failures from the 15 patients with local control, with sensitivity to detect local control of 100% (95% confidence interval 78-100%), specificity 100% (95% confidence interval 16-100%) and positive predictive value 100% (95% confidence interval 78-100%). Our results show a high level of efficacy for fractionated photon radiotherapy after surgery, in keeping with other series. In addition, we found that although surgical debulking is essential, a small residual tumour volume may still be controlled with high-dose photon radiotherapy. This information may be relevant during neurosurgical planning, possibly allowing a reduction in risk of serious neurological deficits. This should encourage the further development of sophisticated photon radiotherapy, for patients unsuitable for proton therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980136"}
{"pmid": "20980137", "title": "Patterns of retreatment by radiotherapy.", "content": "Patterns of retreatment by radiotherapy. To describe patterns of radiotherapy retreatment by cancer type in order to develop methods of modelling retreatment for better service planning and benchmarking. We examined an institutional database of all patients who received their first megavoltage radiotherapy for any type of cancer at the Liverpool and Macarthur Cancer Therapy Centres over the period 1997-2006. The database contains patient demographic data, dates, treatment sites and doses of radiotherapy. The treatment sites were entered as free text and were recoded into a limited number of sites; primary site, bone, brain, soft tissue, other and multiple, so that retreatment sites could be grouped for stratification and analysis. Multiple treatment sites that were part of a single treatment to a primary (for example, primary site and nodes) were recoded as 'primary'. The total retreatment ratio was defined as the number of episodes of radiotherapy divided by the number of cases in the cohort. In the period 1997-2006, 7853 patients had received 9859 episodes of radiotherapy, giving a total retreatment ratio of 26 per 100 patients. In total, 6524 patients (83%) received only one episode of treatment and 1329 received two or more episodes of treatment. The average number of retreatments was 0.26. The tumour type with the highest mean number of retreatments was myeloma (1.05), followed by unknown primary (0.41), lung (0.34) and melanoma (0.32). The lowest mean number of retreatments was for the brain (0.06). The median time between treatment episodes was longest for breast cancer (12.5 months), then colorectal cancer (12.3 months), head and neck cancers (9.0 months), lung cancer (3.8 months) and prostate cancer (5.9 months). The retreatment ratio for the cohort was affected by the length of follow-up and by the tumour type. The mean number of retreatments varied from 0.06 for central nervous system malignancy to 1.05 for myeloma, with an average of 0.026.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980137"}
{"pmid": "20980138", "title": "Recycling carbon fibre reinforced polymers for structural applications: technology review and market outlook.", "content": "Recycling carbon fibre reinforced polymers for structural applications: technology review and market outlook. Both environmental and economic factors have driven the development of recycling routes for the increasing amount of carbon fibre reinforced polymer (CFRP) waste generated. This paper presents a review of the current status and outlook of CFRP recycling operations, focusing on state-of-the-art fibre reclamation and re-manufacturing processes, and on the commercialisation and potential applications of recycled products. It is shown that several recycling and re-manufacturing processes are reaching a mature stage, with implementations at commercial scales in operation, production of recycled CFRPs having competitive structural performances, and demonstrator components having been manufactured. The major challenges for the sound establishment of a CFRP recycling industry and the development of markets for the recyclates are summarised; the potential for introducing recycled CFRPs in structural components is discussed, and likely promising applications are investigated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980138"}
{"pmid": "20980139", "title": "LED-based interferometric reflectance imaging sensor for quantitative dynamic monitoring of biomolecular interactions.", "content": "LED-based interferometric reflectance imaging sensor for quantitative dynamic monitoring of biomolecular interactions. Label-free optical biosensors have been established as proven tools for monitoring specific biomolecular interactions. However, compact and robust embodiments of such instruments have yet to be introduced in order to provide sensitive, quantitative, and high-throughput biosensing for low-cost research and clinical applications. Here we present the Interferometric Reflectance Imaging Sensor (IRIS) using an inexpensive and durable multi-color LED illumination source to monitor protein-protein and DNA-DNA interactions. We demonstrate the capability of this system to dynamically monitor antigen-antibody interactions with a noise floor of 5.2 pg/mm(2) and DNA single mismatch detection under denaturing conditions in an array format. Our experiments show that this platform has comparable sensitivity to high-end label-free biosensors at a much lower cost with the capability to be translated to field-deployable applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980139"}
{"pmid": "20980140", "title": "Oil extraction from Scenedesmus obliquus using a continuous microwave system--design, optimization, and quality characterization.", "content": "Oil extraction from Scenedesmus obliquus using a continuous microwave system--design, optimization, and quality characterization. A 1.2 kW, 2450 MHz resonant continuous microwave processing system was designed and optimized for oil extraction from green algae (Scenedesmus obliquus). Algae-water suspension (1:1 w/w) was heated to 80 and 95°C, and subjected to extraction for up to 30 min. Maximum oil yield was achieved at 95°C and 30 min. The microwave system extracted 76-77% of total recoverable oil at 20-30 min and 95°C, compared to only 43-47% for water bath control. Extraction time and temperature had significant influence (p<0.0001) on extraction yield. Oil analysis indicated that microwaves extracted oil containing higher percentages of unsaturated and essential fatty acids (indicating higher quality). This study validates for the first time the efficiency of a continuous microwave system for extraction of lipids from algae. Higher oil yields, faster extraction rates and superior oil quality demonstrate this system's feasibility for oil extraction from a variety of feedstock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980140"}
{"pmid": "20980141", "title": "Screening and construction of Saccharomyces cerevisiae strains with improved multi-tolerance and bioethanol fermentation performance.", "content": "Screening and construction of Saccharomyces cerevisiae strains with improved multi-tolerance and bioethanol fermentation performance. In this study, a systemic analysis was initially performed to investigate the relationship between fermentation-related stress tolerances and ethanol yield. Based on the results obtained, two elite Saccharomyces cerevisiae strains, Z8 and Z15, with variant phenotypes were chosen to construct strains with improved multi-stress tolerance by genome shuffling in combination with optimized initial selection. After three rounds of genome shuffling, a shuffled strain, YZ1, which surpasses its parent strains in osmotic, heat, and acid tolerances, was obtained. Ethanol yields of YZ1 were 3.11%, 10.31%, and 10.55% higher than those of its parent strains under regular, increased heat, and high gravity fermentation conditions, respectively. YZ1 was applied to bioethanol production at an industrial scale. Results demonstrated that the variant phenotypes from available yeast strains could be used as parent stock for yeast breeding and that the genome shuffling approach is sufficiently powerful in combining suitable phenotypes in a single strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980141"}
{"pmid": "20980142", "title": "Effect of nitrogen, salt, and iron content in the growth medium and light intensity on lipid production by microalgae isolated from freshwater sources in Thailand.", "content": "Effect of nitrogen, salt, and iron content in the growth medium and light intensity on lipid production by microalgae isolated from freshwater sources in Thailand. Four green microalgae (TRG, KB, SK, and PSU) identified as Botryococcus spp. by morphological criteria were isolated from lakes and freshwater ponds in southern Thailand. In nitrogen-rich medium the strains achieved a lipid content of 25.8%, 17.8%, 15.8% and 5.7%, respectively. A combination of nitrogen deficiency, moderately high light intensity (82.5 μE m(-2) s(-1)) and high level of iron (0.74 mM) improved lipid accumulation in TRG, KB, SK, and PSU strains up to 35.9%, 30.2%, 28.4% and 14.7%, respectively. The lipid contents and plant oil-like fatty acid composition of the microalgae suggested their potential as biodiesel feedstock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980142"}
{"pmid": "20980143", "title": "Gasification of palm empty fruit bunch in a bubbling fluidized bed: a performance and agglomeration study.", "content": "Gasification of palm empty fruit bunch in a bubbling fluidized bed: a performance and agglomeration study. Gasification of palm empty fruit bunch (EFB) was investigated in a pilot-scale air-blown fluidized bed. The effect of bed temperature (650-1050 °C) on gasification performance was studied. To explore the potential of EFB, the gasification results were compared to that of sawdust. Results showed that maximum heating values (HHV) of 5.37 and 5.88 (MJ/Nm3), dry gas yield of 2.04 and 2.0 (Nm3/kg), carbon conversion of 93% and 85 % and cold gas efficiency of 72% and 71 % were obtained for EFB and sawdust at the temperature of 1050 °C and ER of 0.25. However, it was realized that agglomeration was the major issue in EFB gasification at high temperatures. To prevent the bed agglomeration, EFB gasification was performed at temperature of 770±20 °C while the ER was varied from 0.17 to 0.32. Maximum HHV of 4.53 was obtained at ER of 0.21 where no agglomeration was observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980143"}
{"pmid": "20980145", "title": "Enhanced production of ansamitocin P-3 by addition of isobutanol in fermentation of Actinosynnema pretiosum.", "content": "Enhanced production of ansamitocin P-3 by addition of isobutanol in fermentation of Actinosynnema pretiosum. Supply of isobutanol to enhance the production of anti-tumor agent ansamitocin P-3 (AP-3) in medium containing agro-industrial residues was investigated with analysis of gene transcription, enzyme activity, and intermediate accumulation. Under the optimal addition of isobutanol, about 4-fold improvement of AP-3 production was obtained, and the consumption of isobutanol and accumulation of isobutyrate, malonyl-CoA, and acetyl-CoA were observed. Compared to the control without isobutanol addition, activities of both isobutanol dehydrogenase and valine dehydrogenase were enhanced in isobutanol supplemented culture. Transcription level of genes in AP-3 biosynthetic and isobutyryl-CoA catabolic pathways responded to isobutanol addition in a similar way as AP-3 biosynthesis. It is concluded that isobutanol addition was an effective strategy for increasing AP-3 production via regulation of gene transcription and pools of precursors, and the information obtained might be helpful to the fermentation productivity improvement on large scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980145"}
{"pmid": "20980144", "title": "Modeling of the Contact-Adsorption-Regeneration (CAR) activated sludge process.", "content": "Modeling of the Contact-Adsorption-Regeneration (CAR) activated sludge process. Contact-Adsorption-Regeneration (CAR) process is a cost-effective system for wastewater treatment and has a potential for application in less-developed regions. To offer a better understanding of this process, a mathematical model was established on the basis of Activated Sludge Model No. 1 (ASM1) and by incorporating the adsorption and different hydrolysis processes. The model predictions were compared with the measured data in terms of effluent concentrations and removals of both chemical oxygen demand (COD) and NH(4)(+)-N. A good agreement between the predicted and measured data was observed, indicating that the model was capable of predicting the rapid adsorption, COD removal and nitrification processes in the CAR system. This work provides an experimental and theoretical basis for the application of the CAR process in less-developed regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980144"}
{"pmid": "20980146", "title": "Full description of copper uptake by algal biomass combining an equilibrium NICA model with a kinetic intraparticle diffusion driving force approach.", "content": "Full description of copper uptake by algal biomass combining an equilibrium NICA model with a kinetic intraparticle diffusion driving force approach. In this work kinetic and equilibrium studies related to copper binding to the protonated macroalga Sargassum muticum are reported. An intraparticle-diffusion linear driving force (LDF) model has been chosen for the quantitative description of the kinetics at several initial metal concentrations. Copper intraparticle homogeneous diffusion coefficient (D(h)) obtained is in the range 0.2-0.9×10(-10) m(2) s(-1). NICA isotherm is demonstrated to constitute a substantial improvement with respect to a simpler Langmuir competitive equation. The binding parameters were chosen to provide the best simultaneous description of the equilibrium experiments. Values of log K(Cu) (4.3), n(Cu) (1) and p (0.31) in NICA isotherm, and log K(Cu) (3.5-5) in Langmuir competitive model, have been obtained. These parameters have been also used to predict the competition between copper and cadmium for binding sites. Two acids, HNO(3) and HCl, have been tested to evaluate their effectiveness to release copper from the metal-laden biomass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980146"}
{"pmid": "20980147", "title": "Synthesis and biological evaluation of novel leonurine-SPRC conjugate as cardioprotective agents.", "content": "Synthesis and biological evaluation of novel leonurine-SPRC conjugate as cardioprotective agents. The synthesis and biological evaluation of novel leonurine-SPRC conjugate, 3,5-dimethoxy-4-(2-amino-3-prop-2-ynylsulfanyl-propionyl)-benzoic acid 4-guanidino-butyl ester (1) is reported in this Letter. It is designed to improve the pharmacology efficiency by combining leonurine with S-propargyl-L-cysteine (SPRC), a cysteine analog, via a phenolic hydroxyl ester bond, which could be readily hydrolyzed to release bioactive leonurine and SPRC. Pharmacological evaluation has shown that 1 possesses potent cardioprotective effect against hypoxia-induced neonatal rat ventricular myocytes damage at lower molar concentration (10-fold less than leonurine required and 100-fold less than SPRC required). The mechanism is in partial related to improve hydrogen sulfide production, anti-oxidative stress and anti-apoptosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980147"}
{"pmid": "20980148", "title": "Design and synthesis of threading intercalators to target DNA.", "content": "Design and synthesis of threading intercalators to target DNA. Threading intercalators are high affinity DNA binding agents that bind by inserting a chromophore into the duplex and locating one group in each groove. The first threading intercalators that can be conjugated to acids, sulfonic acids and peptides to target them to duplex DNA are described, based upon the well studied acridine-3- or 4-carboxamides. Cellular uptake of the parent acridine is rapid and it can be visualized in the nucleus of cells. Both the parent compounds and their conjugates maintain antitumor activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980148"}
{"pmid": "20980150", "title": "Time and frequency analysis of the static balance in young adults with Down syndrome.", "content": "Time and frequency analysis of the static balance in young adults with Down syndrome. The main objective of this study is to understand the differences in equilibrium control between normal subjects and those with Down syndrome. A total of 54 subjects participated voluntarily, divided into control group and Down syndrome group. The equilibrium of the subjects was tested under two conditions: bipedal support with eyes open and closed. The signals were analyzed in a time and frequency domain. The statistical parameters selected (i.e., RMS distance, mean velocity, mean frequency and sway area) to analyze the behavior of the center of pressures (CoP) are calculated employing the result of the combination of the time series data in both directions (i.e. resultant distance). In order to calculate the frequency bands produced by the displacements of the CoP, a Fast Fourier Transform of the data was performed. The group with Down syndrome showed poorer static equilibrium control than the control group in the time domain. In the frequency domain, we found differences between the groups in the distribution of energy in the frequency bands analyzed. In addition, we observed the existence of an interaction effect of the group and the condition tested (p<0.001). These findings show that in the absence of visual information, the control group increases the energy at low frequencies, while the group with Down syndrome decreases it. Additionally, the lower amount of energy observed in this band under the 'eyes closed' condition may serve to identify abnormalities in the functioning of the vestibular apparatus of individuals with Down syndrome and/or difficulties experienced by these individuals in extracting relevant information from this route.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980150"}
{"pmid": "20980149", "title": "SATB1 gene expression and breast cancer prognosis.", "content": "SATB1 gene expression and breast cancer prognosis. Recently it has been shown that the genome organizer SATB1 plays an important role in breast cancer progression and predicts a poor prognosis. However its prognostic value compared to markers as the estrogen receptor is currently unclear. The expression levels of SATB1 mRNA from Affymetrix microarray in a cohort of 2058 breast cancer samples and its prognostic impact were analyzed. There was no significant difference in disease-free survival among ER negative cancers but instead a benefit for high SATB1 expression among ER positive tumors (p = 0.042). However, even in ER positive cancer no independent prognostic value in multivariate analysis with standard parameters was observed. Thus the use of SATB1 as target or prognostic marker for breast cancer should be viewed with caution and a possible confounding effect of the estrogen receptor status of the tumor should be taken into account when analysing new markers as SATB1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980149"}
{"pmid": "20980152", "title": "Kissing aneurysms of the distal anterior cerebral artery.", "content": "Kissing aneurysms of the distal anterior cerebral artery. Kissing aneurysms, a particular type of multiple aneurysm are rare. A kissing aneurysms was identified at the distal anterior cerebral artery (ACA) in a 59-year-old male patient diagnosed with subarachnoid hemorrhage (SAH). The use of three-dimensional intracranial CT angiograms revealed that kissing aneurysms (that is, an aneurysm with a bilateral symmetrical mirror image) were located at the distal ACA and diffuse SAH in basal, sylvian, and interhemispheric cisterns. Both conventional carotid angiograms showed that both distal ACA aneurysms were seen separately on both internal carotid angiograms. Two aneurysms were observed simultaneously on carotid compression of either side. Some particular cautions required in diagnosing and treating kissing aneurysms are discussed, together with a literature review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980152"}
{"pmid": "20980151", "title": "Dopamine agonist-induced substance addiction: the next piece of the puzzle.", "content": "Dopamine agonist-induced substance addiction: the next piece of the puzzle. Traditional antiparkinson treatment strategies strive to balance the antiparkinson effects of dopaminergic drugs with the avoidance of motor response complications. Dopamine agonists have an established role in delaying the emergence of motor response complications or reducing motor \"off\" periods. The recent recognition of a range of \"behavioural addictions\" that are linked to dopamine agonist use has highlighted the role of dopamine in brain reward function and addiction disorders in general. Dopamine agonists have now even been linked occasionally to new substance addictions. The challenge now for the Parkinsonologist is to also balance the net benefits of using dopamine agonists for their motor effects with avoiding the harm from behavioural compulsions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980151"}
{"pmid": "20980155", "title": "Developing dual functional allosteric modulators of GABA(A) receptors.", "content": "Developing dual functional allosteric modulators of GABA(A) receptors. Positive modulators at benzodiazepine sites of α2- and α3-containing GABA(A) receptors are believed to be anxiolytic. Negative allosteric modulators of α5-containing GABA(A) receptors enhance cognition. By oocyte two-electrode voltage clamp and subsequent structure-activity relationship studies, we discovered cinnoline and quinoline derivatives that were both positive modulators at α2-/α3-containing GABA(A) receptors and negative modulators at α5-containing GABA(A) receptors. In addition, these compounds showed no functional activity at α1-containing GABA(A) receptors. Such dual functional modulators of GABA(A) receptors might be useful for treating comorbidity of anxiety and cognitive impairments in neurological and psychiatric illnesses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980155"}
{"pmid": "20980153", "title": "Synthesis and structure-activity studies of benzyl ester meperidine and normeperidine derivatives as selective serotonin transporter ligands.", "content": "Synthesis and structure-activity studies of benzyl ester meperidine and normeperidine derivatives as selective serotonin transporter ligands. A series of benzyl esters of meperidine and normeperidine were synthesized and evaluated for binding affinity at serotonin, dopamine and norepinephrine transporters. The 4-methoxybenzyl ester 8b and 4-nitrobenzyl ester 8c in the meperidine series and 4-methoxybenzyl ester 14a in the normeperidine series exhibited low nanomolar binding affinities at the SERT (K(i) values <2nM) and high SERT selectivity (DAT/SERT >1500 and NET/SERT >1500).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980153"}
{"pmid": "20980154", "title": "Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis.", "content": "Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis. In the present study, a structured-based virtual screening (VS) of differently substituted furocoumarins and analogues has been carried out against nuclear factor kappa B (NF-κB), with the objective of selecting molecules able to inhibit the binding of this transcription factor to the DNA. The focus library was developed starting from chemical structures obtained from the literature, as well as retrieving compounds from available commercial databases. A two dimensional substructure searching method based on four different chemical scaffolds was used for this purpose. Among the 10 highest-scored ligands selected from the docking studies, five commercially available molecules were investigated in biological assays. Four furocoumarin derivatives showed IC(50) values in the range of 40-100 μM in inhibiting NF-κB/DNA interactions studied by electrophoretic mobility shift assay (EMSA). Three compounds significantly inhibited NF-κB dependent biological functions (expression of IL-8) in cellular analysis based on Pseudomonas aeruginosa infection of cystic fibrosis IB3-1 cells. These findings validated the virtual screening approach here presented and reinforce the successful results of our previously computational studies aimed at the identification of molecules targeting NF-κB. The discovered novel compounds could be of relevance to identify more potent inhibitors of NF-κB dependent biological functions beneficial to control lung inflammation occurring in patients affected by cystic fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980154"}
{"pmid": "20980156", "title": "The promoters of 3 celery salt-induced phloem-specific genes as new tools for monitoring salt stress responses.", "content": "The promoters of 3 celery salt-induced phloem-specific genes as new tools for monitoring salt stress responses. Genes induced by a progressive 3 week salt stress (final NaCl concentration 300 mM) were identified in the phloem of celery (Apium graveolens L., cv Vert d'Elne). A subtractive library was constructed and screened for salt-induced, phloem-specific genes. Work was focused on phloem due to its central role in inter-organ exchanges. Three genes were studied in more details, 2 coding for metallothioneins (AgMT2 and AgMT3) and one for a new mannitol transporter (AgMaT3). Expression of a reporter gene in transgenic Arabidopsis under control of promoter of each gene was located in the phloem. pAgMT2 has a typical phloem pattern with slight induction by salt stress. pAgMT3 and pAgMaT3 expression was induced by salt stress, except in minor veins. pAgMaT3 was highly active in stressed roots. The promoters described here could be regarded as new tools for engineering salt-resistant plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980156"}
{"pmid": "20980157", "title": "Identical homologs of the Galanthus nivalis agglutinin in Zea mays and Fusarium verticillioides.", "content": "Identical homologs of the Galanthus nivalis agglutinin in Zea mays and Fusarium verticillioides. The structural domain corresponding to the Galanthus nivalis agglutinin (GNA) is a mannose-binding motif that was originally discovered in plants but according to recent data also occurs in other eukaryotes and prokaryotes. Transcriptome analyses revealed that Fusarium verticillioides expresses a protein (FvGLLc1) identical to a recently identified cytoplasmic/nuclear GNA-like lectin from maize (ZmGLLc). The FvGLLc1 and ZmGLLc gene sequences are nearly identical in the coding region as well as in the intron and the 5 and 3 prime untranslated regions. However, whereas the Fusarium genome contains only a single gene with an intron, both an intronless and an intron containing lectin gene can be amplified from maize DNA. Southern blot analysis confirmed the presence of this cytoplasmic GNA-like gene in the maize and rice genome. A comparative analysis of the products amplified by different PCRs using genomic DNA from Fusarium species and maize DNA samples from sterile as well as contaminated plant material strongly indicated that the GNA-like sequence found in maize grown under sterile conditions is not derived from a contaminating Fusarium species. Furthermore, using a PCR-based approach it could be demonstrated that this particular type of lectin occurs also in other plants from distant taxa and is markedly conserved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980157"}
{"pmid": "20980159", "title": "Awake thoracoscopic bullaplasty.", "content": "Awake thoracoscopic bullaplasty. Staple excision of emphysematous bullae through general anesthesia is the standard surgical treatment of bullous emphysema. We have developed a new surgical technique entailing thoracoscopic bullaplasty performed in fully awake patients through sole epidural anesthesia. This prospective nonrandomized trial included 35 patients undergoing awake thoracoscopic bullaplasty between 2002 and 2009. Preoperative work-up included computed tomography with algorithm for quantitative measurement of the bulla volume. Outcome measures included patient's satisfaction with the anesthesia, scored into four grades (1=unsatisfactory; 4=excellent); ratio of arterial oxygen tension to fraction of inspired oxygen (PaO(2)/FiO(2)), and postoperative assessment of standard clinical measures at 6, 12, and 36 months. There were 29 men and six women with a median age of 60 years. Median volume of the bulla was 688 ml. Awake bullaplasty was successfully completed in 34 patients. Perioperatively, PaO(2)/FiAO(2) decreased significantly (analysis of variance (ANOVA), P<0.0001) though remaining satisfactory (>300 mmHg), whereas PaCO(2) increased intraoperatively (ANOVA, P<0.0001) but returned to baseline values 1h after surgery (P=0.20). There was no mortality; four patients had air leaks longer than 7 days. Mean hospital stay was 4.9 ± 2.2 days. Comparisons between pre- to 6-month changes in outcome measures showed improvements (P<0.0001) in forced expiratory volume in 1s (FEV(1)) (+0.37 l), residual volume (-1.16 l), dyspnea index (-2), and standard 6-min walk test (SMWT) (+71 m). These improvements lasted for up to 36 months and in no patient did operated bullae recur. Our study suggests that awake thoracoscopic bullaplasty was well tolerated and easily performed in the majority of the patients, and significant clinical improvements lasted for up to 36 months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980159"}
{"pmid": "20980158", "title": "Cycloheximide-mediated superinduction of genes involves both native and foreign transcripts in rice (Oryza sativa L.).", "content": "Cycloheximide-mediated superinduction of genes involves both native and foreign transcripts in rice (Oryza sativa L.). Rice seedlings subjected to heat shock show rapid and transient induction of Oshsp17.4-CI, Oshsp17.9A-CI and OsClpB-cyt/hsp100 transcripts. When the seedlings were pre-treated with protein synthesis inhibitor cycloheximide, levels of the above transcripts during heat shock were more elevated than those seen with heat shock alone. Heat stress and cycloheximide co-treatment resulted in higher transcript accumulation in comparison to cycloheximide pre-treatment followed by heat stress. In transgenic plants raised with OsClpB-cyt/hsp100 promoter driving expression of the reporter gus gene, expression of the gus transcript was subjected to similar superinduction event as was seen with native OsClpB-cyt/hsp100 transcripts in untransformed plants. Yeast cells transformed with variably-sized rice ClpB-cyt/hsp100 promoter driving expression of the lacZ reporter transcript showed that specific sequences of the promoter region may be implicated in superinduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980158"}
{"pmid": "20980160", "title": "Effect of psoriasis activity on VEGF and its soluble receptors concentrations in serum and plaque scales.", "content": "Effect of psoriasis activity on VEGF and its soluble receptors concentrations in serum and plaque scales. Vascular endothelial growth factor (VEGF) demonstrating pro-angiogenic activity promote new blood vessel formation in psoriatic lesions. The aim of this study was to evaluate the serum concentrations of VEGF, its soluble receptors (sVEGF R1 and R2) and VEGF content in scales of patients with psoriasis. To analyze possible association with activity of the disease, serum and scales from plaques were collected from 59 patients with exacerbated chronic plaque-type psoriasis. Mean concentrations of VEGF and sVEGF R1 in sera of patients were respectively two and four times higher than in healthy controls. Serum VEGF and sVEGF R1, but not sVEGF R2 demonstrated significant correlation with psoriasis area and severity index (PASI). There was also significant correlation between VEGF levels in serum and scales. Serum sVEGF R1 concentration was significantly elevated even in patients with low psoriasis activity (PASI<10), whereas increase of serum VEGF became significant in patients with medium activity (PASI: 10-20). Levels of serum VEGF and sVEGF R1 were the highest in patients with PASI>20. We confirmed association of both serum and scales VEGF concentrations with degree of psoriasis activity and demonstrated predominant increase of sVEGF R1 vs. VEGF in serum of patients with low psoriasis activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980160"}
{"pmid": "20980161", "title": "Association of high mobility group box-1 protein levels with sepsis and outcome of severely burned patients.", "content": "Association of high mobility group box-1 protein levels with sepsis and outcome of severely burned patients. The study was performed to observe the systemic release and kinetics of high mobility group box-1 protein (HMGB1) in burned patients. 106 patients were included, and they were divided into three groups with different burn sizes: group I, group II and group III. Healthy volunteers served as normal controls (n=25). The peripheral blood samples were collected on postburn days (PBD) 1, 3, 7, 14, and 21. The blood samples were used to detect levels of HMGB1 in plasma by ELISA kits for human. Gene expression of HMGB1 in peripheral blood mononuclear cells was assessed by real-time quantitative PCR taking GAPDH as the internal standard. The levels of HMGB1 were significantly elevated on PBD 1-21 in patients with various burn sizes compared with normal controls, and there were obvious differences between group I and group III. The HMGB1 levels were significantly higher in septic patients than those without sepsis on PBD 7-21. Among septic patients, the HMGB1 levels in the survival group were markedly lower than those with fatal outcome on PBD 3-21. Extensive burn injury could result in significantly increased HMGB1 levels, which appears to be associated with the development of sepsis and fatal outcome of major burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980161"}
{"pmid": "20980162", "title": "A rat tracheal model to investigate stent-induced tissue hyperplasia: a pilot study.", "content": "A rat tracheal model to investigate stent-induced tissue hyperplasia: a pilot study. To evaluate the feasibility of stent placement and the formation of stent-induced tissue hyperplasia and to verify matrix metalloproteinase (MMP) expression in stent-induced tissue hyperplasia in a rat tracheal model. In a pilot study, four rats were used to verify MMP expression in stent-induced tracheal tissue hyperplasia based on zymography and Western blot analysis. In the main experiment, 12 rats were divided into two groups with different stent-mesh gap sizes (group I, 1.23 × 1.92 mm; group II, 0.80 × 1.80 mm). The stent was 4 mm in diameter and 8 mm long. Follow-up tracheogram was performed before sacrifice 3 weeks after stent placement. The gross and the microscopic findings were evaluated. Stent placement was technically successful in all rats. During follow-up, two rats (one from each group) died within 4 days after stent placement, and one stent in group II was placed outside the trachea. MMP-9 expression was significantly higher in tissue hyperplasia than in control normal tissue. The excised specimens showed tissue hyperplasia through the mesh, and all of the stents had become incorporated into the wall of the trachea. The papillary projection thickness, granulation tissue area, percentage of granulation tissue area, and degree of inflammatory cell infiltration were higher in group II than in group I, but there was no statistically significant difference. In this study, stent placement was feasible, and the formation of stent-induced tissue hyperplasia was evident in a rat tracheal model. MMP-9 overexpression was evident in the stent-induced tracheal tissue hyperplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980162"}
{"pmid": "20980163", "title": "Aberrant ovarian and uterine feeding from the renal artery at the end of gestation: two cases.", "content": "Aberrant ovarian and uterine feeding from the renal artery at the end of gestation: two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980163"}
{"pmid": "20980164", "title": "Cardiovascular effects and predictability of cardiovascular collapse after repeated intravenous bolus injections of absolute ethanol in anesthetized pigs.", "content": "Cardiovascular effects and predictability of cardiovascular collapse after repeated intravenous bolus injections of absolute ethanol in anesthetized pigs. To evaluate the effects of repeated intravenous bolus injections of absolute ethanol on cardiopulmonary hemodynamic changes and to investigate the predictability of ethanol-induced cardiovascular collapse in anesthetized pigs. Twenty pigs aged 3-6 months and weighing 28-38 kg were enrolled in the study. Absolute ethanol (0.1 mL/kg of body weight) was repeatedly injected through the inferior vena cava central to the renal vein at 10-minute intervals up to a total volume of 1.0 mL/kg. The subjects were divided into a cardiovascular collapse group and a no-collapse group according to the development or absence of cardiac collapse. Among the 20 pigs, 12 died before the final injection. Hemodynamic parameters measured immediately before the injection of absolute ethanol did not differ between the cardiovascular collapse group and the no-collapse group except that among animals with cardiovascular collapse, the injection immediately before the one causing cardiovascular collapse resulted in significant increases in the following hemodynamic parameters: mean pulmonary arterial pressure (P < .01), pulmonary vascular resistance (P = .04), and right ventricular end-diastolic volume (P = .02). No such increases were observed in the no-collapse group. Hemodynamic profiles in pigs obtained immediately before intravenous injection of absolute ethanol did not predict the subsequent occurrence of cardiovascular collapse except after the injection immediately preceding the one resulting in cardiovascular collapse. In this animal model, significant increases in select hemodynamic parameters occurred after the injection immediately preceding the one resulting in cardiovascular collapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980164"}
{"pmid": "20980165", "title": "Correlation between tumor perfusion and lipiodol deposition in hepatocellular carcinoma after transarterial chemoembolization.", "content": "Correlation between tumor perfusion and lipiodol deposition in hepatocellular carcinoma after transarterial chemoembolization. To study the correlation of tumor perfusion with lipiodol deposition in hepatocellular carcinoma (HCC) after transarterial chemoembolization with multidetector computed tomography (MDCT) perfusion imaging. MDCT perfusion imaging was performed in 24 patients with HCC 1 to 7 days before chemoembolization. The computed tomography (CT) perfusion parameters, such as hepatic arterial perfusion (HAP), hepatic portal perfusion (HPP), total liver perfusion (TLP), and hepatic arterial perfusion index (HAPI), were calculated with the slope method. The follow-up CT scans (noncontrast) were performed 4 weeks after chemoembolization to analyze lipiodol deposition. The lipiodol deposition in the tumor was classified into three grades and compared with CT perfusion parameters before chemoembolization. The HAP and TLP of tumors before chemoembolization were correlated with the grades of lipiodol deposition in tumors after chemoembolization (r = 0.768, P < .0001 and r = 0.616, P = .001, respectively). However, the HPP and HAPI of the tumors were not related to the grades of iodized oil deposition (r = 0.227, P = .286 and r = 0.111, P = .607, respectively). Higher HAP was correlated with better lipiodol deposition, and lower HAP was correlated with poorer lipiodol deposition. MDCT perfusion imaging has the potential to help select more appropriate patients with HCC for chemoembolization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980165"}
{"pmid": "20980166", "title": "Celiac axis as the upper origin of ascending left colic artery: an unusual multidetector computed tomography finding.", "content": "Celiac axis as the upper origin of ascending left colic artery: an unusual multidetector computed tomography finding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980166"}
{"pmid": "20980167", "title": "Angiogenesis and current antiangiogenic strategies for the treatment of cancer.", "content": "Angiogenesis and current antiangiogenic strategies for the treatment of cancer. Angiogenesis is a complex process critical for embryonic development and for survival. It is also a critical player in many pathologic processes, most notably in neoplasia. The cell signaling pathways involved in angiogenesis have become key targets for drug design, with more than 2,500 clinical trials currently under way. This review summarizes the essential features of angiogenesis and discusses therapeutic strategies that have been applied to specific diseases known to be associated with perturbation of normal angiogenic control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980167"}
{"pmid": "20980168", "title": "Evaluation of formation of granulation tissue caused by metallic stent placement in a rat urethral model.", "content": "Evaluation of formation of granulation tissue caused by metallic stent placement in a rat urethral model. To evaluate the feasibility of metallic stent placement and the formation of granulation tissue caused by stent placement in a rat urethral model. A bare self-expanding metallic stent was inserted in the urethra under fluoroscopic guidance in 20 male Sprague-Dawley rats. Ten rats were euthanized at 4 weeks (group A), and the other 10 were euthanized at 8 weeks after stent placement (group B). Stenosis diameter, number of epithelial layers, degree of inflammatory cell infiltration, thickness of submucosal fibrosis, and percentage of granulation tissue area were assessed. Stent placement was technically successful in all rats. Urethrograms showed perforation in three rats, partial migration in three, and stone formation in four. Granulation tissue formation was observed in all rats at the stent-implanted urethra, and the average percentage of granulation tissue area accounted for 41% and 45% of the original urethral lumen area in groups A and B, respectively. Urethrograms and urethral specimens showed significantly less stenosis diameter, less thickness of submucosal fibrosis, and lower percentage of granulation tissue area in the proximal urethra than in the distal urethra in both groups (P < .05). Histologic results demonstrated significantly fewer epithelial layers in group B compared with group A (P = .028). Placement of a self-expandable metallic stent proved to be feasible in the rat urethra and an efficient approach to stimulate granulation tissue formation as a potential model for reproducing the mechanisms of restenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980168"}
{"pmid": "20980169", "title": "Health-related quality of life and exercise tolerance in recipients of heart transplants and left ventricular assist devices: a prospective, comparative study.", "content": "Health-related quality of life and exercise tolerance in recipients of heart transplants and left ventricular assist devices: a prospective, comparative study. The aim of this study was to evaluate and compare health-related quality of life (HRQoL) and physical exercise tolerance in patients after heart transplantation (HTx) or implantation of a left ventricular assist device (LVAD). A prospective, comparative design was used to characterize changes over time in HRQoL (SF-36) and exercise tolerance in patients after HTx (n = 54) and during LVAD support (n = 36). Nine LVAD patients were lost for follow-up. The majority of patients in both groups were male (97%); the LVAD cohort tended to be younger (p = 0.06). HRQoL improved significantly in HTx patients in the SF-36 physical (p = 0.02), but not in the psychosocial (p = 0.27) component score during follow-up. In the LVAD group, HRQoL showed improvements for both the SF-36 physical and psychosocial component scores (both p = 0.04). Between-group comparisons revealed better HRQoL for the HTx cohort than the LVAD cohort for 2 of 8 SF-36 subscales. Age-, gender- and body mass index (BMI)-adjusted exercise tolerance (workload; VO(2max)) showed significant improvements for both HTx (p = 0.01) and LVAD (p = 0.01) patients. Adjusted maximum oxygen consumption was higher for HTx patients (p = 0.05) relative to LVAD patients at 8 ± 1 months after implant. HRQoL and exercise capacity increased in both groups over the time-course of the study. After adjusting for relevant variables, HTx patients showed a higher exercise tolerance compared with the LVAD group during follow-up. Thus, future large-scale intervention studies should emphasize the specific needs of these patient cohorts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980169"}
{"pmid": "20980170", "title": "In-hospital delay of elective surgery for high volume procedures: the impact on infectious complications.", "content": "In-hospital delay of elective surgery for high volume procedures: the impact on infectious complications. Development of infectious complications after high volume elective surgical procedures imposes a significant clinical burden to the United States population. This study evaluated the association of in-hospital delay of elective procedures and the subsequent impact on infectious complications after coronary artery bypass graft (CABG) surgery, colon resection, and lung resection. The Nationwide Inpatient Sample was queried between 2003 and 2007, and patients who developed postoperative infectious complications were identified. Time to elective surgery in days from admission was calculated: 0, 1 day, 2 to 5 days, and 6 to 10 days. Infectious complications evaluated included pneumonia, urinary tract infections, postoperative sepsis, and surgical site infections. Chi-square, multivariable logistic regression analyses, analysis of variance, and Cochran-Armitage trend test were used. There were 87,318 CABG procedures, 46,728 colon resections, and 28,960 lung resections evaluated. Total infection rates significantly increased after elective surgery delays: CABG: 0 days, 5.73%;1 day, 6.68%; 2 to 5 days, 9.33%; 6 to 10 days,18.24%; colon resections: 0 days, 8.43 %;1 day, 11.86%; 2 to 5 days,15.79%;6 to 10 days,21.62%; and lung resections: 0 days, 10.17%;1 day, 14.53%; 2 to 5 days, 15.53%; 6 to 10 days, 20.56%, p < 0.0001 for all trends. Trends for increasing infections after delay were significant for pneumonia and sepsis for all procedures (p < 0.0001); urinary tract infections and surgical site infections significantly increased after CABG and colon resection. Age 80 years and older, female gender, black and Hispanic race or ethnicity, and comorbidities including congestive heart failure, chronic pulmonary disease, and renal failure were associated with delay in surgery. Postoperative hospital mortality after delayed procedures was also greater. Mean cost increased after all procedures with delays: CABG, from $25,164 to $42,055 (p < 0.0001); colon resections, from $13,660 to $25,307) (p < 0.0001); and lung resections, from $18,519 to $25,054 (p < 0.0001). In-hospital delay of elective surgery from the day of admission was associated with a significant increase in infectious complications and mortality. This delay was also associated with a significant increase in hospital cost. Future policy directed toward preventing in-hospital delay of elective surgery may offer significant cost savings and decrease infectious complications after elective surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980170"}
{"pmid": "20980171", "title": "Polymorphonuclear cell priming associated with NF-kB activation in patients with severe injury is partially dependent on macrophage migration inhibitory factor.", "content": "Polymorphonuclear cell priming associated with NF-kB activation in patients with severe injury is partially dependent on macrophage migration inhibitory factor. Severe trauma may induce alternations of cytokine response and polymorphonuclear cell (PMN) activity in patients. This study investigated the correlation of plasma migration inhibitory factor (MIF) level and PMN activation after severe injury, and their relationship with clinical outcomes. A prospective observational study was performed at the emergency department and intensive care unit of a university hospital. Thirty-two severe blunt trauma patients (Injury Severity Score greater than 16) with systemic inflammatory response syndrome (SIRS) were enrolled. Age- and gender-matched healthy persons were the controls. Patient blood samples were obtained within 24 hours of and at 72 hours after injury. PMNs were isolated and measured for NF-kBp65 translocation and respiratory burst. Plasma MIF, tumor necrosis factor (TNF)-alpha, interleukin (IL)-6, IL-8, and IL-10 concentrations were measured. Control PMNs were incubated with patient plasma preincubated with anti-MIF antibody or anti-IL-6 antibody; cytokine blockade effects were evaluated. Twelve patients developed organ failure. Compared with patients without organ failure, patients with organ failure had lower blood pressure and a higher base deficit on admission, higher NF-kBp65 translocation and respiratory burst of PMNs, and higher plasma MIF (968 ± 246 pg/mL vs 564 ± 299 pg/mL) and IL-6 (202 ± 91 pg/mL vs 119 ± 84 pg/mL) levels within 24 hours after injury. Plasma MIF had significant positive correlation with NF-kB translocation of PMNs within 24 hours of incurring trauma (R = 0.668). The presence of anti-MIF antibody in patients' plasma obtained within 24 hours, but not at 72 hours, after injury could significantly partially block the NF-kBp65 translocation and respiratory activity of PMNs in the controls. An early increase of plasma MIF associates with NF-kB translocation and respiratory burst in PMNs of severe trauma patients and correlates with higher morbidity. MIF is one of the important factors responsible for early PMN activation and may provide a target of immunomodulation after injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980171"}
{"pmid": "20980172", "title": "Persistence of antibodies to the topical hemostat bovine thrombin.", "content": "Persistence of antibodies to the topical hemostat bovine thrombin. Immunoassays that detect antibovine thrombin product antibodies are not widely available. However, knowing whether these antibodies are present preoperatively would be useful because re-exposure to bovine thrombin-containing products is contraindicated in patients with pre-existing antiproduct antibodies due to the risk of developing immune-mediated coagulopathies. In these exploratory analyses, we characterized one aspect of immune sensitization, the persistence of circulating antibodies after exposure to bovine thrombin product. Elapsed time since a historical surgical procedure with documented or highly likely use of bovine thrombin product was determined for 204 patients enrolled in a recently completed trial. After study completion, baseline samples were assayed for antibovine thrombin product antibodies using validated immunoassays. Antibody data were sorted by time elapsed since the historical procedure. The proportion of patients with antibovine thrombin product antibodies and 95% confidence interval (CI) were determined for each 1-year period, providing an estimate for antibody persistence. Antibovine thrombin product antibodies were detected in 20.7% of patients (23 of 111; 95% CI 14.2%, 29.2%) with ≤1 year since the historical surgical procedure; 6.8% of patients (3 of 44; 95% CI 1.68%, 18.9%) with 1 to <2 years; 16.1% of patients (5 of 31; 95% CI 6.62%, 33.1%) with 2 to <3 years; and 5.6% of patients (1 of 18; 95% CI 0.00%, 27.6%) with ≥3 years since the historical procedure. The proportion of patients with antibovine thrombin product antibodies ranged from 5.6% to 20.7% across the multiyear postoperative window. Clinicians should be aware that antibodies to bovine thrombin products may persist for years after exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980172"}
{"pmid": "20980173", "title": "Surgical site infection in colorectal surgery: a review of the nonpharmacologic tools of prevention.", "content": "Surgical site infection in colorectal surgery: a review of the nonpharmacologic tools of prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980173"}
{"pmid": "20980175", "title": "Management of giant hemangioma of the liver: resection versus observation.", "content": "Management of giant hemangioma of the liver: resection versus observation. Management of patients with giant hemangiomas of the liver encounters persistent controversy. Although recent case series suggest a low complication rate with nonoperative management, the classic paradigm of preventive operative resection remains. A retrospective cohort study was conducted of 492 patients with giant hepatic hemangioma (>4 cm in size) diagnosed between 1985 and 2005 at Mayo Clinic Rochester. Long-term outcomes were assessed by patient survey, with a follow-up of 11 ± 6.4 years. Of 492 patients, 289 responded to the survey. In the nonoperative group (n = 233), 20% had persistent or new onset of hemangioma-associated symptoms, including potentially life-threatening complications in 2%. In the operative group (n = 56), perioperative complications occurred in 14%, including potentially life-threatening complications in 7%. None of the operative patients had persistent or new onset of hemangioma-associated symptoms after resection of the dominant hemangioma. In group comparison, the rate of adverse events was similar (20% versus 14%; p = 0.45) with an overall low risk for potentially life-threatening complications (2% versus 7%; p = 0.07). Size of hemangiomas was not associated with adverse events in either group. Subjective health status and quality of life at follow-up were similar in both groups (p > 0.54). Clinical observation of patients with giant hemangioma of the liver has a similar rate of complications compared with operative management, but might prevent the need for invasive interventions in some patients. Clinical observation is preferred in most patients and operative treatment should be reserved for patients with severe symptoms or disease-associated complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980175"}
{"pmid": "20980176", "title": "Neonatal ovarian lymphangioma.", "content": "Neonatal ovarian lymphangioma. Ovarian cysts are primarily of follicular origin and ovarian lymphangioma is an extremely rare lesion. We report a case of prenatal diagnosis of unilateral ovarian cyst in which pathologic examination revealed an ovarian lymphangioma. Ovarian cystic lymphangioma should be included in the differential diagnosis of an ovarian cyst mass in neonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980176"}
{"pmid": "20980174", "title": "Surgical resection for locoregional esophageal cancer is underutilized in the United States.", "content": "Surgical resection for locoregional esophageal cancer is underutilized in the United States. Although esophagectomy provides the highest probability of cure in patients with esophageal cancer, many candidates are never referred for surgery. We hypothesized that esophagectomy for esophageal cancer is underused, and we assessed the prevalence of resection in national, state, and local cancer data registries. Clinical stage, surgical and nonsurgical treatments, age, and race of patients with cancer of the esophagus were identified from the Surveillance, Epidemiology and End Results (SEER) registry (1988 to 2004), the Healthcare Association of NY State registry (HANYS 2007), and a single referral center (2000 to 2007). SEER identified a total of 25,306 patients with esophageal cancer (average age 65.0 years, male-to-female ratio 3:1). HANYS identified 1,012 cases of esophageal cancer (average age 67 years, M:F ratio 3:1); stage was not available from NY State registry data. A single referral center identified 385 patients (48 per year; average age 67 years, M:F 3:1). For SEER data, logistic regression was used to examine determinants of esophageal resection; variables tested included age, race, and gender. Surgical exploration was performed in 29% of the total and only 44.2% of potentially resectable patients. Esophageal resection was performed in 44% of estimated cancer patients in NY State. By comparison, 64% of patients at a specialized referral center underwent surgical exploration, 96% of whom had resection. SEER resection rates for esophageal cancer did not change between 1988 and 2004. Males were more likely to receive operative treatment. Nonwhites were less likely to undergo surgery than whites (odds ratio 0.45, p < 0.001). Surgical therapy for locoregional esophageal cancer is likely underused. Racial variations in esophagectomy are significant. Referral to specialized centers may result in an increase in patients considered for surgical therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980174"}
{"pmid": "20980177", "title": "Education for life.", "content": "Education for life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980177"}
{"pmid": "20980178", "title": "Chlamydiaceae in cattle: commensals, trigger organisms, or pathogens?", "content": "Chlamydiaceae in cattle: commensals, trigger organisms, or pathogens? Epidemiological data indicate that infection of cattle with chlamydiae such as Chlamydophila (C.) pecorum, C. abortus, C. psittaci and Chlamydia suis, is ubiquitous with mixed infections occurring frequently. The apparent lack of association between infection and clinical disease has resulted in debate as to the pathogenic significance of these organisms, and their tendency to sub-clinical and/or persistent infection presents a challenge to the study of their potential effects. However, recent evidence indicates that chlamydial infections have a substantial and quantifiable impact on livestock productivity with chronic, recurrent infections associated with pulmonary disease in calves and with infertility and sub-clinical mastitis in dairy cows. Data also suggest these infections manifest clinically when they coincide with a number of epidemiological risk factors. Future research should: (1) use relevant animal models to clarify the pathogenesis of bovine chlamydioses; (2) quantify the impact of chlamydial infection at a herd level and identify strategies for its control, including sub-unit vaccine development; and (3) evaluate the zoonotic risk of bovine chlamydial infections which will require the development of species-specific serodiagnostics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980178"}
{"pmid": "20980179", "title": "Qualitative and quantitative ultrashort echo time (UTE) imaging of cortical bone.", "content": "Qualitative and quantitative ultrashort echo time (UTE) imaging of cortical bone. We describe the use of two-dimensional ultrashort echo time (2D UTE) sequences with minimum TEs of 8 μs to image and quantify cortical bone on a clinical 3T scanner. An adiabatic inversion pulse was used for long T(2) water and fat signal suppression. Adiabatic inversion prepared UTE acquisitions with varying TEs were used for T(2) measurement. Saturation recovery UTE acquisitions were used for T(1) measurement. Bone water concentration was measured with the aid of an external reference phantom. UTE techniques were evaluated on cadaveric specimens and healthy volunteers. A signal-to-noise ratio of around 30, contrast-to-noise ratio of around 27/20 between bone and muscle/fat were achieved in tibia in vivo with a nominal voxel size of 0.23 × 0.23 × 6.0 mm(3) in a scan time of 5 min. A mean T(1) of 223 ± 11 ms and mean T(2) of 390 ± 19 μs were found. Mean bone water concentrations of 23.3 ± 1.6% with UTE and 21.7 ± 1.3% with adiabatic inversion prepared UTE sequences were found in tibia in five normal volunteers. The results show that in vivo qualitative and quantitative evaluation of cortical bone is feasible with 2D UTE sequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980179"}
{"pmid": "20980180", "title": "Theoretical studies on the interactions of XIAP-BIR3 domain with bicyclic and tricyclic core monovalent Smac mimetics.", "content": "Theoretical studies on the interactions of XIAP-BIR3 domain with bicyclic and tricyclic core monovalent Smac mimetics. X-linked IAP can bind caspase-9 and inhibit its activity. Mitochondrial protein Smac/DIABLO can also interact with XIAP and relieve the inhibition on caspase-9 to induce apoptosis. A series of artificial Smac mimetics have been used to mimic the Smac N-terminal tetrapeptide AVPI to bind to XIAP-BIR3, but these structural diverse mimetics exhibited distinct binding affinities. To get an insight into the binding nature and optimize the structures, molecular docking and dynamics simulations were used to study the binding of XIAP-BIR3 with three groups of Smac mimetics. The docking results reveal that these Smac mimetics anchored on the surface groove of XIAP-BIR3 and superimposed well with AVPI. The modifications on the seven-membered ring of bicyclic core segment do not strengthen the binding affinity, while a benzyl introduced to the five-membered ring is favorable to the binding. Molecular dynamics simulations on three typical systems show that these complexes are very stable. Hydrogen bonds between the bicyclic core segment and Thr308 play critical roles in maintaining the stability of complex. The binding free energies calculated by MM_PBSA method are consistent with the experimental results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980180"}
{"pmid": "20980181", "title": "Clinical outcomes following hematopoietic stem cell transplantation for the treatment of mucopolysaccharidosis VI.", "content": "Clinical outcomes following hematopoietic stem cell transplantation for the treatment of mucopolysaccharidosis VI. Mucopolysaccharidosis VI (MPS VI, Maroteaux-Lamy Syndrome) is one of approximately 50 known lysosomal storage disorders. MPS VI is characterized by an absence or deficiency of N-acetylgalactosamine 4-sulfatase (arylsulfatase B) resulting in accumulation of dermatan sulfate. Prior to the availability of enzyme replacement therapy (ERT), the clinical management of MPS VI was limited to supportive care and allogeneic hematopoietic stem cell transplantation (HSCT); however, due to the rarity of this disease, little is known about the long-term outcomes of HSCT for MPS VI. The following retrospective study was performed using aggregate data gathered by the Center for International Blood and Marrow Transplant Research (CIBMTR) between 1982 and 2007 to determine survival probability for patients with MPS VI following allogeneic HSCT. This analysis identified 45 MPS VI patients with a median age of 5 years (range, 1-22 years) at the time they received an allogeneic HSCT. Cumulative incidence (95% CI) of acute graft-vs.-host disease at 100 days was 36% (21-53%). Probability of survival was 78% (65-89%) at 100 days and 66% (52-79%) at 1 and 3 years. While these data are based upon small numbers of recipients, they represent the largest series to date and may help clinicians assess the relative risks and benefits of currently available therapies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980181"}
{"pmid": "20980183", "title": "Bone vascularization and remodeling.", "content": "Bone vascularization and remodeling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980183"}
{"pmid": "20980182", "title": "Prevalence of treated diabetes: Geographical variations at the small-area level and their association with area-level characteristics. A multilevel analysis in Southeastern France.", "content": "Prevalence of treated diabetes: Geographical variations at the small-area level and their association with area-level characteristics. A multilevel analysis in Southeastern France. This study estimated geographical variations in the prevalence of treated diabetes (TD) at the small-area level in Southeastern France to determine whether or not the characteristics of these areas (in particular, socioeconomic status or \"SES\") are associated with TD independent of person-level factors. The study used drug reimbursement data for 2008 from the General Health Insurance Scheme in Southeastern France for beneficiaries aged 18 years or over. TD patients were defined as those to whom oral antidiabetic drugs or insulin had been dispensed at least three times within the year. Area (canton) characteristics associated with the prevalence of TD were studied using multilevel Poisson regression. In 2008, the crude prevalence of TD in adults in Southeastern France was 5.14%. In addition, TD prevalence was significantly higher in the more deprived and population-dense cantons independent of person-level factors (age, gender, low SES). This study found a positive association between area deprivation and TD, and adds further evidence to the scanty data so far available on this topic. This finding should contribute to pinpointing priority action areas for programmes of diabetes prevention. However, more research is needed to further elucidate the mechanism(s) linking area deprivation and diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980182"}
{"pmid": "20980184", "title": "Effect of ultrasound and temperature on tomato peroxidase.", "content": "Effect of ultrasound and temperature on tomato peroxidase. Tomato peroxidase (POD) was inactivated by heat and ultrasound. Thermal inactivation of tomato POD was performed at temperatures of 63, 64, 65, 66 and 67°C. Thermal inactivation of POD in tomato showed apparent first-order kinetics. E(a) was calculated from the slopes of Arrhenius plot and found as 14.9×10(4) J/mol. The effect of ultrasound on tomato peroxidase inactivation was investigated at 15%, 25%, 40%, 50% and 75% ultrasonic powers for 20-150 s. It was observed that as the ultrasonic power increased, inactivation rate increased. 100% POD inactivation was observed at 50% power for 150 s and at 75% power for 90 s of ultrasonication. Regeneration of POD activity was investigated for the samples exposed to ultrasound at different ultrasonic powers. It was observed that at 15% and 25% ultrasonic powers, residual enzyme activity increased linearly, whereas at powers of 40%, 50% and 75% residual enzyme activity increased nonlinearly. There was no regeneration in the samples which 100% enzyme inactivation obtained by ultrasound. A significant decrease in vitamin C content of tomato extract was observed as a function of temperature and treatment time, whereas ultrasonic treatment had no significant effect on vitamin C content of tomato extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980184"}
{"pmid": "20980185", "title": "Synthesis of chalcone (3-(4-fluorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one): advantage of sonochemical method over conventional method.", "content": "Synthesis of chalcone (3-(4-fluorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one): advantage of sonochemical method over conventional method. In this work, an attempt was made to synthesize chalcone (3-(4-fluorophenyl)-1-(4-methoxyphenyl)prop-2-en-1-one) by condensation of 4-fluorobenzaldehyde with 1-(4-methoxyphenyl)ethanone under basic conditions by using both conventional (NUS) and sonochemical (US) methods. A simple condensation reaction of 4-fluorobenzaldehyde and 1-(4-methoxyphenyl)ethanone using potassium hydroxide as a base was carried out for the study. The synthesized chalcone derivative was characterized for FTIR, NMR, elemental analyses and studied for XRD, PSM, TGA and SEM properties to evaluate its performance obtained under ultrasonic energy. It was observed that complete conversion to chalcone occurred in 10 min by sonochemical method and in 4h by conventional method. Also it was found that crystallinity of the US synthesized chalcone was found to be increased by 63% than that of NUS synthesized chalcone. Finally, it has been observed that chalcone synthesis using sonochemical method is an energy efficient technique over conventional method (almost 90% of energy saving).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980185"}
{"pmid": "20980186", "title": "The investigation of sonocatalytic activity of Er3+:YAlO3/TiO2-ZnO composite in azo dyes degradation.", "content": "The investigation of sonocatalytic activity of Er3+:YAlO3/TiO2-ZnO composite in azo dyes degradation. In this work, the emphasis was mainly placed on investigating the sonocatalytic activity of TiO(2)-ZnO mixed with Er(3+):YAlO(3), namely, Er(3+):YAlO(3)/TiO(2)-ZnO composite. It is able to utilize the sonoluminescence light to improve the sonocatalytic degradation of organic dyes. The Er(3+):YAlO(3) as up-conversion luminescence agent was synthesized by sol-gel and auto-combustion method, and then Er(3+):YAlO(3)/TiO(2)-ZnO composite as sonocatalyst were prepared by ultrasonic dispersion and liquids boil method. The prepared up-conversion luminescence agent and composites were characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM). Acid Red B dye was selected to examine the sonocatalytic activity of Er(3+):YAlO(3)/TiO(2)-ZnO composite. The degradation reaction processes were monitored by UV-vis spectrophotometer and ion chromatogram. The influences on the activity of the Er(3+):YAlO(3)/TiO(2)-ZnO such as Ti/Zn molar ratio, heat-treated temperature and heat-treated time were studied. The results showed that the Er(3+):YAlO(3)/TiO(2)-ZnO composite exhibited a significantly high sonocatalytic activity compared with other catalysts in the degradation of Acid Red B. And the sonocatalyst with 1:1 Ti/Zn molar ratio heat-treated at 550°C for 60min showed the highest sonocatalytic activity. At last, the experiment also indicated that it has a good sonocatalytic activity to degrade other organic dyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980186"}
{"pmid": "20980187", "title": "Ultrasound-assisted extraction of phillyrin from Forsythia suspensa.", "content": "Ultrasound-assisted extraction of phillyrin from Forsythia suspensa. Forsythia suspensa (Thunb.) Vahl is one of the most widely used traditional Chinese medicines, and possesses important biological activities, such as antibacterial, antiviral, anti-inflammatory and antioxidant activities. Phillyrin is the main bioactive component of Forsythia suspensa. In this paper, ultrasound-assisted extraction of phillyrin from Forsythia suspensa was studied with HPLC-photodiode array detection. Effects of several experimental parameters, such as type and concentration of extracting solvent, ratio of liquid to material, extraction temperature, and time of sonication on extraction efficiencies of phillyrin from Forsythia suspensa were evaluated. The optimal extraction conditions were 1g plant sample with 10 ml of 20% methanol and the extraction for 60 min at 60°C under ultrasonic irradiation. Under the optimum conditions, the yield of phillyrin was 0.713±0.009 mg/g. The results indicated that the ultrasound-assisted extraction is a very useful method for the extraction of important phytochemicals from plant materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980187"}
{"pmid": "20980188", "title": "Comparison of pulse rate variability with heart rate variability during obstructive sleep apnea.", "content": "Comparison of pulse rate variability with heart rate variability during obstructive sleep apnea. We investigate whether pulse rate variability (PRV) extracted from finger photo-plethysmography (Pleth) waveforms can be the substitute of heart rate variability (HRV) from RR intervals of ECG signals during obstructive sleep apnea (OSA). Simultaneous measurements (ECG and Pleth) were taken from 29 healthy subjects during normal (undisturbed sleep) breathing and 22 patients with OSA during OSA events. Highly significant (p<0.01) correlations (1.0>r>0.95) were found between heart rate (HR) and pulse rate (PR). Bland-Altman plot of HR and PR shows good agreement (<5% difference). Comparison of 2 min recording epochs demonstrated significant differences (p<0.01) in time, frequency domains and complexity analysis, between normal and OSA events using PRV as well as HRV measures. Results suggest that both HRV and PRV indices could be used to distinguish OSA events from normal breathing during sleep. However, several variability measures (SDNN, RMSSD, HF power, LF/HF and sample entropy) of PR and HR were found to be significantly (p<0.01) different during OSA events. Therefore, we conclude that PRV provides accurate inter-pulse variability to measure heart rate variability under normal breathing in sleep but does not precisely reflect HRV in sleep disordered breathing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980188"}
{"pmid": "20980189", "title": "Development of a novel method for surgical implant design optimization through noninvasive assessment of local bone properties.", "content": "Development of a novel method for surgical implant design optimization through noninvasive assessment of local bone properties. A method was developed to improve the design of locking implants by finding the optimal paths for the anchoring elements, based on a high resolution pQCT assessment of local bone mineral density (BMD) distribution and bone micro-architecture (BMA). The method consists of three steps: (1) partial fixation of the implant to the bone and creation of a reference system, (2) implant removal and pQCT scan of the bone, and (3) determination of BMD and BMA of all implant-anchoring locations along the actual and alternative directions. Using a PHILOS plate, the method uncertainty was tested on an artificial humerus bone model. A cadaveric humerus was used to quantify how the uncertainty of the method affects the assessment of bone parameters. BMD and BMA were determined along four possible alternative screw paths as possible criteria for implant optimization. The method is biased by a 0.87 ± 0.12 mm systematic uncertainty and by a 0.44 ± 0.09 mm random uncertainty in locating the virtual screw position. This study shows that this method can be used to find alternative directions for the anchoring elements, which may possess better bone properties. This modification will thus produce an optimized implant design.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980189"}
{"pmid": "20980190", "title": "A complete, non-lumped, and verifiable set of upper body segment parameters for three-dimensional dynamic modeling.", "content": "A complete, non-lumped, and verifiable set of upper body segment parameters for three-dimensional dynamic modeling. Dynamic models of the human trunk have been extensively used to investigate the biomechanics of lower back pain and postural instability in different populations. Despite their diverse applications, previous models rely on intrinsic upper body segment parameters (UBSP), e.g., each segment's mass-inertia characteristics. However, a comprehensive UBSP set allowing state-of-the-art, three-dimensional (3D) dynamic modeling does not exist to date. Therefore, our objective was to establish a UBSP set of all vertebral trunk segments that is accurate and complete. Based on high-resolution, transverse color images, anatomical structures of the Male Visible Human (MVH) were digitally reconstructed via commercial software. Subsequently, we identified the 3D spinal joint and 3D center of mass coordinates, the mass, and the moment of inertia tensor for 24 vertebral trunk segments and 4 upper limb segments (two segments per arm). Since the MVH images are public domain, the parameters are uniquely verifiable and expandable to also include lower limb parameters. To demonstrate the UBSP set's practicality, the parameters were finally implemented in a previously proposed inverse dynamics model of the upper body. Our findings reveal that an accurate and complete UBSP set has been obtained that will be beneficial to (1) systemize thinking in postural control studies; (2) quantify the effect of impact forces on the head and trunk (e.g., during whiplash); (3) suggest population-specific experiments based on theoretical insights into trunk dynamics (e.g., regarding lower back pain); or (4) assess the feasibility of new surgical techniques (e.g., spinal fusion) and neuroprostheses (e.g., after spinal cord injury).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980190"}
{"pmid": "20980192", "title": "Inequalities in smoking in the Czech Republic: societal or individual effects?", "content": "Inequalities in smoking in the Czech Republic: societal or individual effects? Smoking constitutes one of the main public health problems worldwide. In the Czech Republic, one of the post-communist countries undergoing societal transition, there was a significant decrease in smoking prevalence during 1985-1997, followed by certain stagnation in prevalence of smokers. The most serious problem is the smoking among young population and socially disadvantaged groups. This paper examines social inequalities in smoking in the Czech population using multilevel approach. Data were analysed by multilevel modelling using smoking in the past, current smoking and current moderate/heavy smoking as outcomes of interest. Men were significantly more likely to be smokers than women. Further, the analysis confirmed that current smoking is the most common among young people. Education was strongly inversely related to all smoking outcomes. Smoking was also significantly more reported by divorced and unemployed individuals. While the association between small-area characteristics and smoking was limited, smoking was more common in the areas with higher unemployment and higher proportion of non-Czech nationals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980192"}
{"pmid": "20980191", "title": "The influence of contrast agent injection on physiological flow in the circle of Willis.", "content": "The influence of contrast agent injection on physiological flow in the circle of Willis. X-ray videodensitometry allows in vivo flow measurements from gradients in contrast agent concentration. However, the injection of contrast agent alters the flow to be measured. Here, the temporal, spatial, and inter-patient variability of the response to injection are examined. To this purpose, an injection is prescribed in the internal carotid in a 1D wave propagation model of the arterial circulation. Although the resulting effect of injection is constant over a cardiac cycle, the response does vary with the location within the cerebral circulation and the geometry of the circle of Willis. At the injection site, the injection partly suppresses the incoming blood flow, such that the distal flow is increased by approximately 10%. This corresponds to approximately 20% of the injection rate added to the blood flow during injection, depending on the vascular geometry. In the communicating arteries, the flow direction is reversed during injection. Since the measured flow is not equal to the physiological blood flow, the effect of injection should be taken into account when deriving the flow from travelling contrast agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980191"}
{"pmid": "20980193", "title": "Reconnecting plants and pollinators: challenges in the restoration of pollination mutualisms.", "content": "Reconnecting plants and pollinators: challenges in the restoration of pollination mutualisms. Ecological restoration of plant-pollinator interactions has received surprisingly little attention, despite animal-mediated pollination underpinning reproduction of the majority of higher plants. Here, we offer a conceptual and practical framework for the ecological restoration of pollination mutualisms. Through the use of targeted restoration plantings to attract and sustain pollinators and increased knowledge of the ecological requirements of pollinators, we propose that pollination could be successfully restored in degraded ecosystems. The challenge for pollination biologists is to integrate their findings with those of plant restoration ecologists to ensure sustainable pollination in restored ecosystems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980193"}
{"pmid": "20980194", "title": "Space, time, and number: a Kantian research program.", "content": "Space, time, and number: a Kantian research program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980194"}
{"pmid": "20980195", "title": "Crystal and molecular structure of N-(4-nitrophenyl)-β-alanine--its vibrational spectra and theoretical calculations.", "content": "Crystal and molecular structure of N-(4-nitrophenyl)-β-alanine--its vibrational spectra and theoretical calculations. The N-(4-nitrophenyl)-β-alanine in crystalline form directly by the addition of 4-nitroaniline to the acrylic acid in aqueous solution has been obtained. The title β-alanine derivative crystallizes in the P2(1)/c space group of monoclinic system with four molecules per unit cell. The X-ray geometry of β-alanine derivative molecule has been compared with those obtained by molecular orbital calculations corresponding to the gas phase. In the crystal the molecules related by an inversion center interact via symmetrically equivalent O-H···O hydrogen bonds with O···O distance of 2.656(2) Å forming a dimeric structure. The dimers of β-alanine derivative weakly interact via N-H···O hydrogen bonds between the H atom of β-amine groups and one of O atom of nitro groups. The room temperature powder vibrational (infrared and Raman) measurements are in accordance with the X-ray analysis. In aqueous solution of 4-nitroaniline and acrylic acid, the double CC bond of vinyl group of acrylic acid breaks as result of 4-nitroaniline addition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980195"}
{"pmid": "20980197", "title": "Temporal lobe seizure prediction based on a complex Gaussian wavelet.", "content": "Temporal lobe seizure prediction based on a complex Gaussian wavelet. Abnormal synchronisation change is closely associated with the process of seizure generation. The immediate and accurate detection of the changes in synchronisation may offer advantages in seizure prediction. Thus, we develop a phase synchronisation detection method for this purpose. An analysis of phase synchronisation based on the complex Gaussian wavelet transform (PSW) was conducted to detect synchronised phases of long-lasting scalp electroencephalograph (EEG) recordings from eight epilepsy patients with intractable temporal lobe epilepsy. Four assessment indicators, namely sensitivity, maximum false prediction rate, seizure occurrence period and seizure prediction horizon were used to assess and compare PSW with the analysis of phase synchronisation, based on the Hilbert transform (PSH) and a random predictor Poisson process. An obvious decrease was found upon phase synchronisation prior to visual detection of electroencephalograph seizure onset, which was consistent with the EEG mechanism in the ictal events. The results suggest that PSW is the most effective among the three prediction methods. The results confirm that the analysis of phase synchronisation based on the complex Gaussian wavelet transform can be used for seizure prediction. Phase synchronisation analysis may be a useful algorithm for clinical application in epileptic prediction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980197"}
{"pmid": "20980196", "title": "Comparing cutaneous perception induced by electrical stimulation using rectangular and round shaped electrodes.", "content": "Comparing cutaneous perception induced by electrical stimulation using rectangular and round shaped electrodes. We have investigated the cutaneous perception differences for anodal and cathodal transcranial direct current stimulation (tDCS) and transcranial random noise stimulation (tRNS) between two electrode configurations: a standard, rectangle-shaped, and a circle-shaped, round geometry with the same surface area, and thus, same nominal current distribution. We have aimed to find whether a smaller perimeter length and the absence of corners in the case of the round configuration would lead to altered skin perception characteristics when compared to the rectangular geometry. Twelve subjects were tested for tDCS and tRNS skin perception characteristics in the intensity range of 200-2000 μA using round and rectangular electrode configurations. We have not found any substantial differences between detection thresholds, detection rates, false positive rates or consistent alterations in the sites of perceived stimulation. We conclude that there is no difference between the round and the rectangular electrode configurations regarding their blinding potentials. The results of this investigation indicate that the altering of the electrode geometry to a round configuration is unwarranted for better blinding purposes in future studies using tDCS and tRNS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980196"}
{"pmid": "20980198", "title": "Nanotechnology in molecular medicine.", "content": "Nanotechnology in molecular medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980198"}
{"pmid": "20980199", "title": "TubercuList--10 years after.", "content": "TubercuList--10 years after. TubercuList (http://tuberculist.epfl.ch/), the relational database that presents genome-derived information about H37Rv, the paradigm strain of Mycobacterium tuberculosis, has been active for ten years and now presents its twentieth release. Here, we describe some of the recent changes that have resulted from manual annotation with information from the scientific literature. Through manual curation, TubercuList strives to provide current gene-based information and is thus distinguished from other online sources of genome sequence data for M. tuberculosis. New, mostly small, genes have been discovered and the coordinates of some existing coding sequences have been changed when bioinformatics or experimental data suggest that this is required. Nucleotides that are polymorphic between different sources of H37Rv are annotated and gene essentiality data have been updated. A host of functional information has been gleaned from the literature and many new activities of proteins and RNAs have been included. To facilitate basic and translational research, TubercuList also provides links to other specialized databases that present diverse datasets such as 3D-structures, expression profiles, drug development criteria and drug resistance information, in addition to direct access to PubMed articles pertinent to particular genes. TubercuList has been and remains a highly valuable tool for the tuberculosis research community with >75,000 visitors per month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980199"}
{"pmid": "20980200", "title": "The MycoBrowser portal: a comprehensive and manually annotated resource for mycobacterial genomes.", "content": "The MycoBrowser portal: a comprehensive and manually annotated resource for mycobacterial genomes. In this paper, we present the MycoBrowser portal (http://mycobrowser.epfl.ch/), a resource that provides both in silico generated and manually reviewed information within databases dedicated to the complete genomes of Mycobacterium tuberculosis, Mycobacterium leprae, Mycobacterium marinum and Mycobacterium smegmatis. A central component of MycoBrowser is TubercuList (http://tuberculist.epfl.ch), which has recently benefited from a new data management system and web interface. These improvements were extended to all MycoBrowser databases. We provide an overview of the functionalities available and the different ways of interrogating the data then discuss how both the new information and the latest features are helping the mycobacterial research communities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980200"}
{"pmid": "20980202", "title": "Quick path finding--quick algorithmic solution for unambiguous labeling of phylogenetic tree nodes.", "content": "Quick path finding--quick algorithmic solution for unambiguous labeling of phylogenetic tree nodes. Ever increasing amounts of genetic information stored in sequential databases require efficient methods to automatically reveal their phylogenetic relationships. A framework for in silico unambiguous analysis of phylogenetic trees, based on information contained in tree's topology, together with its branches length, is proposed. The resulting, translated tree has all nodes labeled, with no constraints on nodes' degree, and the subsequent finding of evolutionary pathways from the QPF-translated tree is robust and straightforward. Main features of the method are: small demands on computational time, and the ability to analyze phylogenies obtained prior to the proposed QPF analysis by any traditional tree-building technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980202"}
{"pmid": "20980201", "title": "Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies.", "content": "Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies. cardiovascular risk factors are associated with dementia and cognitive decline. We investigated the effects of renin-angiotensin system blockade on cognitive function in patients aged 55 years and older with established atherosclerotic cardiovascular disease or diabetes with end-organ damage in two clinical trials. in the main study, ONTARGET, a double-blind, double-dummy, randomised controlled trial, the effects on cardiovascular outcomes of standard doses of an angiotensin-converting enzyme (ACE) inhibitor (ramipril), an angiotensin-receptor blocker (telmisartan), and a combination of the drugs were evaluated in 25 620 participants. In the parallel TRANSCEND trial, the effects of telmisartan were compared with those of placebo in 5926 participants intolerant to ACE inhibitors. Secondary outcomes included cognitive impairment (defined by investigator-reported diagnosis of dementia or significant cognitive dysfunction, or a score of ≤ 23 on the Mini-Mental State Examination [MMSE]) and cognitive decline (a decrease of ≤ 3 points on the MMSE from baseline during follow-up). Analyses were by intention to treat. We pooled data from these studies to identify baseline predictors of cognitive impairment and its frequency according to mean systolic blood pressure during follow-up. These studies were registered with ClinicalTrials.gov, number NCT00153101. During a median duration of 56 months (IQR 51-64) of follow-up in ONTARGET, cognitive impairment occurred in 652 (8%) of 7865 patients allocated ramipril, 584 (7%) of 7797 allocated telmisartan, and 618 (8%) of 7807 allocated combination treatment (combination vs ramipril, odds ratio [OR] 0·95, 95% CI 0·85-1·07, p= 0·39; telmisartan vs ramipril, OR 0·90, 0·80-1·01, p = 0·06). Corresponding figures for cognitive decline were 1314 (17%), 1279 (17%), and 1240 (17%) in each of the groups, respectively (telmisartan vs ramipril, OR 0·97, 0·89-1·06, p= 0·53; combination vs ramipril, OR 0·95, 0·88-1·04, p=0·28). In TRANSCEND, cognitive impairment occurred in 239 (9%) of 2694 participants allocated telmisartan compared with 245 (9%) of 2689 allocated placebo (OR 0·97, 0·81-1·17, p= 0·76). The corresponding figures for cognitive decline were 454 (17%) and 412 (16%; OR 1·10, 0·95-1·27, p= 0·22). In patients with cardiovascular disease or diabetes, different approaches to blocking of the renin-angiotensin system had no clear effects on cognitive outcomes. Although patients with the lowest systolic blood pressure had the greatest preservation of cognitive function, meta-regression analyses did not show any benefits of blood-pressure lowering on cognition over several years of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980201"}
{"pmid": "20980204", "title": "Comparison of knowledge on travel related health risks and their prevention among humanitarian aid workers and other travellers consulting at the Institut Pasteur travel clinic in Paris, France.", "content": "Comparison of knowledge on travel related health risks and their prevention among humanitarian aid workers and other travellers consulting at the Institut Pasteur travel clinic in Paris, France. Non-Governmental Organization (NGO) workers are a group of travellers highly exposed to infectious diseases due to the conditions and duration of their stay. Yet little is known about their knowledge concerning travel related health risks and their prevention. From July to September 2008 a self-administered questionnaire was given to all NGO workers coming for pre-travel consultation and to a comparison group of non-NGO travellers. It examined traveller's knowledge about malaria, traveller's diarrhea, transmission routes of infectious diseases and vaccine availability in both groups. 249 NGO employees and 304 non-NGO travellers were surveyed. Mean age (33.7 vs 34.7 years) and sex ratio (M/F 1.16 vs 1.29) were comparable in both groups. Travel destination was more often Africa (75% vs 39%) and duration of travel was longer in the NGO group (75% vs 15% more than 1 month). NGO travellers had significantly better knowledge about the transmission routes of infectious diseases : percentages of accurate answers varied from 20% for Japanese encephalitis, 31% for yellow fever and 41% for hepatitis A to 70% for dengue and 96% for malaria, versus respectively 9%, 17%, 40%, 54% and 94% for the comparison group. However no differences were observed between the two groups concerning the means to prevent malaria or traveller's diarrhea, or the symptoms necessitating medical consultation. In the sub-group analyses medical professionals (23% of the NGO group) performed better than other NGO workers. Even though the knowledge was slightly better in the NGO group, there are still important gaps and a combined effort of all actors is needed to improve the security of expatriated humanitarian aid workers, in particular for the non-medical staff.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980204"}
{"pmid": "20980203", "title": "Tailored sutureless meatoplasty: a new technique for correcting meatal stenosis.", "content": "Tailored sutureless meatoplasty: a new technique for correcting meatal stenosis. Standard practice for meatoplasty includes the use of sutures to evert the mucosa. We present a novel technique that is equivalent to standard meatoplasty without the need for suturing. A retrospective chart review was performed of patients who presented with primary meatal stenosis in 2007-2009. One group underwent a tailored, sutureless meatoplasty performed by one surgeon. The second group underwent a standard meatoplasty with mucosal advancement and suturing of the mucosal edges by another surgeon. Data were collected regarding demographics, presenting symptoms, symptom resolution, and postoperative complications. These were then compared between the two groups. Preoperative and postoperative uroflowmetry data were collected for the sutureless group to demonstrate objective improvement. Of 85 patients, aged 2-17 years, 60 underwent the tailored, sutureless procedure while 25 had a standard meatoplasty. The majority of patients presented with a deviated and/or narrowed stream of urine. There was no statistical difference between the two groups in regard to symptom resolution. Uroflowmetry data analyzed for 20 patients in the sutureless group demonstrated a significant improvement in Q(max) and flow pattern; there was no significant change in % post-void residual. No patient had a complication in either group, or presented with recurrence. Tailored sutureless meatoplasty is comparable to meatoplasty with mucosal advancement in resolving symptoms, improving uroflowmetry parameters, and complication rate, but is more efficient and cost effective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980203"}
{"pmid": "20980207", "title": "The European cystic fibrosis patient registry: the power of sharing data.", "content": "The European cystic fibrosis patient registry: the power of sharing data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980207"}
{"pmid": "20980208", "title": "Rapid screening of monoamine oxidase B inhibitors in natural extracts by capillary electrophoresis after enzymatic reaction at capillary inlet.", "content": "Rapid screening of monoamine oxidase B inhibitors in natural extracts by capillary electrophoresis after enzymatic reaction at capillary inlet. A facile capillary electrophoresis (CE) method was developed for the screening of monoamine oxidase B (MAO-B) inhibitors in natural extracts. In this method, the enzymatic reaction occurred at the capillary inlet during a predetermined waiting period, followed by the electrophoretic separation of the reaction compounds, and detected by their UV absorbance at 280 nm. Conditions for the separation of substrates, products and enzyme were optimized. The optimal buffer composition was 50 mM N-2-hydroxyethyl-piperazine-N'-2-ethane sulphonic acid (HEPES) solution containing 10 mM SDS (pH=7.4). Under the optimal condition, the baseline separation of substrates, products and enzyme was achieved within 2 min. The present method was used to determine MAO-B kinetic constants, K(i), K(m) and IC₅₀ based on quantitative of the substrate peak area compared with the reference electropherogram obtained from without the inhibitor. A validation study shows good reproducibility for both migration time (RSD=1.8%) and peak area (RSD=3.9%). Finally, the screening of 16 natural extracts was performed, and 2 natural extracts from Fructus crataegi and Radix polygoni multiflori were identified to be positive for MAO-B inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980208"}
{"pmid": "20980209", "title": "Development and validation of a sensitive and selective UHPLC-MS/MS method for simultaneous determination of both free and total eicosapentaeonic acid and docosahexenoic acid in human plasma.", "content": "Development and validation of a sensitive and selective UHPLC-MS/MS method for simultaneous determination of both free and total eicosapentaeonic acid and docosahexenoic acid in human plasma. A sensitive, selective, and quantitative method for the simultaneous determination of free and total eicosapentaeonic acid (EPA) and docosahexenoic acid (DHA) has been developed and validated in human plasma using fatty acid free human serum albumin as a surrogate matrix. Clean-up for free EPA and DHA employs a liquid-liquid extraction with hexane to remove plasma interferences and provide for cleaner chromatography. The method for total EPA and DHA requires a digestion of the triglycerides followed by liquid-liquid extraction with hexane. Ultra high performance liquid chromatography (UHPLC) technology on a BEH C18 stationary phase column with 1.7 μm particle size was used for chromatographic separation, coupled to tandem mass spectrometry (UHPLC-MS/MS). The method for free EPA and DHA was validated over the concentration range of 0.05-25 μg/mL, while total EPA and DHA concentration range was 0.5-250 μg/mL. The results from assay validation show that the method is rugged, precise, accurate, and well suited to support pharmacokinetic studies. To our knowledge, this work represents the first UHPLC-MS/MS based method that combines both free and total EPA and DHA with a relatively small sample volume (25 μL aliquot) and a run time of 1.5 min, facilitating automation and high throughput analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980209"}
{"pmid": "20980210", "title": "Challenges and opportunities in oncoproteomics.", "content": "Challenges and opportunities in oncoproteomics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980210"}
{"pmid": "20980211", "title": "Forthcoming challenges in the management of direct-acting antiviral agents (DAAs) for hepatitis C.", "content": "Forthcoming challenges in the management of direct-acting antiviral agents (DAAs) for hepatitis C. Agents that specifically target the replication cycle of the virus direct-acting antiviral agents (DAAs) by directly inhibiting the NS3/4A serine protease, the NS5B polymerase and NS5A are currently in clinical development. The need to achieve serum drug concentrations able to suppress viral replication is a key factor for a successful antiviral therapy and the prevention of resistance. Thus pharmacokinetics parameters became important issues for drugs used in the therapy of hepatitis C. The ratio of C(min)/IC(50) (inhibitory quotient or IQ) can provide a surrogate measure of a drug's ability to suppress HCV replication, by taking into account the relationship between plasma drug levels and viral susceptibility to the drug. Ritonavir boosting may be a useful strategy to improve pharmacokinetic parameters. Characterising resistance to DAAs in clinical trials is essential for the management of a drug regimen to reduce the development of resistance and thereby maximise SVR rate. The lesson of HIV therapy, provide a compelling case for the exploration of combinations of direct-acting antiviral agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980211"}
{"pmid": "20980205", "title": "Hmong food helps us remember who we are: perspectives of food culture and health among Hmong women with young children.", "content": "Hmong food helps us remember who we are: perspectives of food culture and health among Hmong women with young children. To examine perspectives on food habits, acculturation, and health among Hmong women with young children in northern California. Qualitative interviews were conducted with 15 Hmong mothers with young children in a low-income community of northern California. The interviews were transcribed and coded based on the principles of grounded theory. The main themes that emerged from the interviews included comparisons between American and Hmong food cultures, food culture preservation, obesity issues, diverse acculturation processes, and intergenerational food habits. Hmong food culture has been identified as the representation of their healthful lifestyle, self-identity, and social support. At the same time, mothers are facing enormous challenges in bridging 2 extreme generations; the less acculturated, immigrant adults and the highly acculturated, US-born children in their households. Addressing the healthful aspects of Hmong food culture and healthful options of American food should be a focus of nutrition-related programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980205"}
{"pmid": "20980212", "title": "Employment of mid-level providers in primary care and control of diabetes.", "content": "Employment of mid-level providers in primary care and control of diabetes. Examine potential associations between inclusion of mid-level providers in United States Veterans Affairs (VA) primary care programs and diabetes control. We established a cohort of diabetes patients (alive October 1, 1999) using the VA Diabetes Registry and VA corporate databases. 1999 VA Survey of Primary Care Practices data were combined with individual-patient information. We used a two-level hierarchical model to determine the relationship between staffing characteristics and hemoglobin A1c (HbA1c), among 88,682 patients from 198 clinics. Inclusion of nurse practitioners (NPs) at relatively limited levels (% of all providers who are NPs) in the primary care program was significantly associated with HbA1c lower by 0.31 percentage points (95% CI, -0.50% to -0.12%) compared to programs that did not include NPs. Having some level of NP staffing vs. no NP staffing was associated HbA1c lower by 0.25%. Inclusion of physician assistants (PAs) in primary care programs was generally not associated with a statistically significant difference in HbA1c. The exception is that moderate levels of PA staffing were associated with slightly higher HbA1c [0.18%, 95% CI, 0.02-0.34)]. Diabetes control among primary care patients appeared to benefit from inclusion of NPs, while an analogous association was not found for PAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980212"}
{"pmid": "20980206", "title": "Predictors of low-income, obese mothers' use of healthful weight management behaviors.", "content": "Predictors of low-income, obese mothers' use of healthful weight management behaviors. To examine the influence of personal and environmental factors on healthful weight management behaviors mediated through self-efficacy among low-income obese mothers. Cross-sectional design. Special Supplemental Nutrition Program for Women, Infants, and Children in Wisconsin. Two hundred eighty-four obese mothers aged 18-34 years. Personal factors (eg, eating low-fat/low-calorie food for weight management), environmental factors, self-efficacy, and weight management behaviors. Data were collected via self-administered written questionnaires. Latent class cluster analysis and structural logistic regression. Women who perceived more importance of eating low-fat/low-calorie food for weight management were more likely to practice multiple behavioral strategies to manage their weight (odds ratio = 0.37) than women who perceived less importance of eating low-fat/low-calorie food for weight management. Women who reported higher positive mood self-efficacy were more likely (odds ratio = 1.63) to practice multiple strategies to manage their weight than women who reported lower positive mood self-efficacy. Environmental factors did not predict use of multiple healthful weight management behaviors. No mediation effect was found. Stressing the importance of food choices and reinforcing learners' self-confidence to make healthful choices at parties and celebrations may be helpful ways to address common barriers to healthful weight management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980206"}
{"pmid": "20980219", "title": "The Indian Ocean dipole and cholera incidence in Bangladesh: a time-series analysis.", "content": "The Indian Ocean dipole and cholera incidence in Bangladesh: a time-series analysis. It has been reported that the El Niño-Southern Oscillation (ENSO) influences the interannual variation of endemic cholera in Bangladesh. There is increased interest in the influence of the Indian Ocean dipole (IOD), a climate mode of coupled ocean-atmosphere variability, on regional ocean climate in the Bay of Bengal and on Indian monsoon rainfall. We explored the relationship between the IOD and the number of cholera patients in Bangladesh, controlling for the effects of ENSO. Time-series regression was performed. Negative binomial models were used to estimate associations between the monthly number of hospital visits for cholera in Dhaka and Matlab (1993-2007) and the dipole mode index (DMI) controlling for ENSO index [NINO3, a measure of the average sea surface temperature (SST) in the Niño 3 region], seasonal, and interannual variations. Associations between cholera cases and SST and sea surface height (SSH) of the northern Bay of Bengal were also examined. A 0.1-unit increase in average DMI during the current month through 3 months before was associated with an increase in cholera incidence of 2.6% [(95% confidence interval (CI), 0.0-5.2; p = 0.05] in Dhaka and 6.9% (95% CI, 3.2-10.8; p < 0.01) in Matlab. Cholera incidence in Dhaka increased by 2.4% (95% CI, 0.0-5.0; p = 0.06) after a 0.1-unit decrease in DMI 4-7 months before. Hospital visits for cholera in both areas were positively associated with SST 0-3 months before, after adjusting for SSH (p < 0.01). These findings suggest that both negative and positive dipole events are associated with an increased incidence of cholera in Bangladesh with varying time lags.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980219"}
{"pmid": "20980213", "title": "Association between circulating specific leukocyte types and blood pressure: the atherosclerosis risk in communities (ARIC) study.", "content": "Association between circulating specific leukocyte types and blood pressure: the atherosclerosis risk in communities (ARIC) study. Although total white blood cell (WBC) count has been associated with hypertension, the association between specific WBC types and blood pressure (BP) levels has not been studied. In a cohort of 5746 middle-age African-American and white adults free of clinical cardiovascular disease and cancer and not taking hypertension or anti-inflammatory medications, BP was measured at baseline and 3, 6, and 9 years later. Levels of circulating neutrophils, lymphocytes, and monocytes were measured at baseline. In African-Americans, but much less so in whites, increased neutrophil levels and decreased lymphocyte levels were significantly associated with elevation of BP but did not influence the rate of change of BP over time. The mean BP difference between the highest and lowest quartiles of neutrophils was approximately 8 mm Hg for systolic BP (SBP), 4 mm Hg for mean arterial pressure (MAP), and 5 mm Hg for pulse pressure (PP). The mean BP difference between the lowest and highest quartiles of lymphocytes was approximately 6 mm Hg for SBP, 2 mm Hg for diastolic BP (DBP), 3 mm Hg for MAP, and 4 mm Hg for PP. Increased neutrophils and decreased lymphocytes are significantly correlated with the regulation of BP and the development of hypertension, especially in African-Americans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980213"}
{"pmid": "20980220", "title": "Fish consumption and mercury exposure among Louisiana recreational anglers.", "content": "Fish consumption and mercury exposure among Louisiana recreational anglers. Methylmercury (MeHg) exposure assessments among average fish consumers in the United States may underestimate exposures among U.S. subpopulations with high intakes of regionally specific fish. We examined relationships among fish consumption, estimated mercury (Hg) intake, and measured Hg exposure within one such potentially highly exposed group, recreational anglers in the state of Louisiana, USA. We surveyed 534 anglers in 2006 using interviews at boat launches and fishing tournaments combined with an Internet-based survey method. Hair samples from 402 of these anglers were collected and analyzed for total Hg. Questionnaires provided information on species-specific fish consumption during the 3 months before the survey. Anglers' median hair Hg concentration was 0.81 µg/g (n = 398; range, 0.02-10.7 µg/g); 40% of participants had levels >1 µg/g, which approximately corresponds to the U.S. Environmental Protection Agency's reference dose. Fish consumption and Hg intake were significantly positively associated with hair Hg. Participants reported consuming nearly 80 different fish types, many of which are specific to the region. Unlike the general U.S. population, which acquires most of its Hg from commercial seafood sources, approximately 64% of participants' fish meals and 74% of their estimated Hg intake came from recreationally caught seafood. Study participants had relatively elevated hair Hg concentrations and reported consumption of a wide variety of fish, particularly locally caught fish. This group represents a highly exposed subpopulation with an exposure profile that differs from fish consumers in other regions of the United States, suggesting a need for more regionally specific exposure estimates and public health advisories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980220"}
{"pmid": "20980221", "title": "Subclinical rhythmic electrographic discharges of adults and transient global amnesia: a causal or casual association?", "content": "Subclinical rhythmic electrographic discharges of adults and transient global amnesia: a causal or casual association? Subclinical rhythmic electrographic discharges of adults (SREDA) is an uncommon distinctive EEG rhythmic pattern with uncertain significance. We report a patient with transient global amnesia in whom an EEG recording, performed after the acute phase of the neurological event, showed SREDA. Based on this EEG finding, we discuss about a possible correlation between SREDA and transient global amnesia. The presence of SREDA in our patient with transient global amnesia seems to be incidental. When described in association with transient global amnesia, SREDA should be recognized in order to avoid misdiagnosis. Although SREDA has been fortuitously described in association with transient global amnesia, a patho-physiological correlation with mechanisms which produce it seems unlikely.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980221"}
{"pmid": "20980214", "title": "Renal dysfunction impairs circadian variation of endothelial function in patients with essential hypertension.", "content": "Renal dysfunction impairs circadian variation of endothelial function in patients with essential hypertension. Some cardiovascular disorders disturb circadian variation of endothelial function. We investigated whether deterioration of renal function alters circadian variation of endothelial function in patients with hypertension. Endothelial function was assessed by the peak forearm blood flow (FBF) response to reactive hyperemia, and 24-hour ambulatory blood pressure monitoring was performed in 25 patients with essential hypertension (61 ± 17 years). Relationships among renal function, 24-hour blood pressure, and endothelial function were analyzed. The ratio of nighttime to daytime mean arterial pressure was inversely correlated with estimated glomerular filtration rate (eGFR) (r = -0.43, P = .03). The FBF response to reactive hyperemia examined at 21:00, but not at 6:30 or 11:30, was significantly correlated with eGFR (r = 0.44, P = .03). Furthermore, the ratio of FBF response measured at 21:00 to that measured at 6:30 was independently correlated with eGFR (β = 0.47, P = .02). Renal dysfunction is associated with the derangement of circadian variation of both endothelial function and blood pressure. Nocturnal blood pressure is elevated, and evening endothelial function deteriorates in parallel with a decline in renal function in hypertensive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980214"}
{"pmid": "20980218", "title": "Vascular and cardiac impairments in rats inhaling ozone and diesel exhaust particles.", "content": "Vascular and cardiac impairments in rats inhaling ozone and diesel exhaust particles. Mechanisms of cardiovascular injuries from exposure to gas and particulate air pollutants are unknown. We sought to determine whether episodic exposure of rats to ozone or diesel exhaust particles (DEP) causes differential cardiovascular impairments that are exacerbated by ozone plus DEP. Male Wistar Kyoto rats (10-12 weeks of age) were exposed to air, ozone (0.4 ppm), DEP (2.1 mg/m(3)), or ozone (0.38 ppm) + DEP (2.2 mg/m(3)) for 5 hr/day, 1 day/week for 16 weeks, or to air, ozone (0.51 or 1.0 ppm), or DEP (1.9 mg/m(3)) for 5 hr/day for 2 days. At the end of each exposure period, we examined pulmonary and cardiovascular biomarkers of injury. In the 16-week study, we observed mild pulmonary pathology in the ozone, DEP, and ozone + DEP exposure groups, a slight decrease in circulating lymphocytes in the ozone and DEP groups, and decreased platelets in the DEP group. After 16 weeks of exposure, mRNA biomarkers of oxidative stress (hemeoxygenase-1), thrombosis (tissue factor, plasminogen activator inhibitor-1, tissue plasminogen activator, and von Willebrand factor), vasoconstriction (endothelin-1, endothelin receptors A and B, endothelial NO synthase) and proteolysis [matrix metalloprotease (MMP)-2, MMP-3, and tissue inhibitor of matrix metalloprotease-2] were increased by DEP and/or ozone in the aorta, but not in the heart. Aortic LOX-1 (lectin-like oxidized low-density lipoprotein receptor-1) mRNA and protein increased after ozone exposure, and LOX-1 protein increased after exposure to ozone + DEP. RAGE (receptor for advanced glycation end products) mRNA increased in the ozone + DEP group. Exposure to ozone or DEP depleted cardiac mitochondrial phospholipid fatty acids (DEP > ozone). The combined effect of ozone and DEP exposure was less pronounced than exposure to either pollutant alone. Exposure to ozone or DEP for 2 days (acute) caused mild changes in the aorta. In animals exposed to ozone or DEP alone for 16 weeks, we observed elevated biomarkers of vascular impairments in the aorta, with the loss of phospholipid fatty acids in myocardial mitochondria. We conclude that there is a possible role of oxidized lipids and protein through LOX-1 and/or RAGE signaling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980218"}
{"pmid": "20980217", "title": "Use of in vitro HTS-derived concentration-response data as biological descriptors improves the accuracy of QSAR models of in vivo toxicity.", "content": "Use of in vitro HTS-derived concentration-response data as biological descriptors improves the accuracy of QSAR models of in vivo toxicity. Quantitative high-throughput screening (qHTS) assays are increasingly being used to inform chemical hazard identification. Hundreds of chemicals have been tested in dozens of cell lines across extensive concentration ranges by the National Toxicology Program in collaboration with the National Institutes of Health Chemical Genomics Center. Our goal was to test a hypothesis that dose-response data points of the qHTS assays can serve as biological descriptors of assayed chemicals and, when combined with conventional chemical descriptors, improve the accuracy of quantitative structure-activity relationship (QSAR) models applied to prediction of in vivo toxicity end points. We obtained cell viability qHTS concentration-response data for 1,408 substances assayed in 13 cell lines from PubChem; for a subset of these compounds, rodent acute toxicity half-maximal lethal dose (LD50) data were also available. We used the k nearest neighbor classification and random forest QSAR methods to model LD50 data using chemical descriptors either alone (conventional models) or combined with biological descriptors derived from the concentration-response qHTS data (hybrid models). Critical to our approach was the use of a novel noise-filtering algorithm to treat qHTS data. Both the external classification accuracy and coverage (i.e., fraction of compounds in the external set that fall within the applicability domain) of the hybrid QSAR models were superior to conventional models. Concentration-response qHTS data may serve as informative biological descriptors of molecules that, when combined with conventional chemical descriptors, may considerably improve the accuracy and utility of computational approaches for predicting in vivo animal toxicity end points.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980217"}
{"pmid": "20980215", "title": "Importance of blood pressure control in left ventricular mass regression.", "content": "Importance of blood pressure control in left ventricular mass regression. Blood pressure (BP) reduction to 140/90 mm Hg or lower using renin-angiotensin-system blockers reportedly provides the greatest left ventricular (LV) mass regression; β-blockers have less effect. This study examined whether combination antihypertensive therapy would provide greater benefit. With a double-blind, parallel-group design, the effects of 3 different combinations, carvedilol controlled-release (CR)/lisinopril, atenolol/lisinopril, and lisinopril, on left ventricular mass index (LVMI) were assessed by MRI after 12 months. Patients were treated to achieve guideline-recommended BP (<140 mm Hg/<90 mm Hg; diabetes: <130 mm Hg/<80 mm Hg). Sample size was calculated to achieve 90% power to detect a 5 g/m(2) difference in mean change from baseline in LVMI between the carvedilol CR/lisinopril group and each of the other treatment groups. Of 287 patients randomized, more than 50% were titrated to maximum dosage; 73% reached targeted BP. At month 12 (last observation carried forward ≥ month 9) for 195 evaluable subjects, mean BP was similar in all groups (carvedilol CR/lisinopril: 128.8/77.9; atenolol/lisinopril: 128.7/76.5; lisinopril: 126.3/80.3 mm Hg). Compared with baseline, mean LVMI decreased to a similar extent in all groups (carvedilol CR/lisinopril: -6.3; atenolol/lisinopril: -6.7; lisinopril: -7.9 g/m(2)). Achievement of targeted BP control is more important than treatment regimen in achieving LV mass reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980215"}
{"pmid": "20980228", "title": "Aggression and sexual behavior in best-selling pornography videos: a content analysis update.", "content": "Aggression and sexual behavior in best-selling pornography videos: a content analysis update. This current study analyzes the content of popular pornographic videos, with the objectives of updating depictions of aggression, degradation, and sexual practices and comparing the study's results to previous content analysis studies. Findings indicate high levels of aggression in pornography in both verbal and physical forms. Of the 304 scenes analyzed, 88.2% contained physical aggression, principally spanking, gagging, and slapping, while 48.7% of scenes contained verbal aggression, primarily name-calling. Perpetrators of aggression were usually male, whereas targets of aggression were overwhelmingly female. Targets most often showed pleasure or responded neutrally to the aggression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980228"}
{"pmid": "20980230", "title": "The impossibility of bearing witness: wartime rape and the promise of justice.", "content": "The impossibility of bearing witness: wartime rape and the promise of justice. Testimonies of wartime sexual violence contribute to the recognition of rape as a serious human rights violation. Although acknowledgement and justice are imperative to ending silence and impunity, this article critiques some commonly held therapeutic assumptions about disclosure through examining the way so-called \"unspeakable\" events are communicated through legal discourse. In this article, the author explores the inherent limitations of language for bearing witness to wartime rape, specifically focusing on international war crimes tribunals. The author argues that trials contribute to the impossibility of bearing witness through both the appropriation of trauma and the failure of law to accommodate traumatic experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980230"}
{"pmid": "20980216", "title": "The relation between blood pressure changes induced by passive leg raising and arterial stiffness.", "content": "The relation between blood pressure changes induced by passive leg raising and arterial stiffness. Passive leg raising (PLR) elicits cardiorespiratory changes because of intra-thoracic blood pooling. We previously found PLR to lower blood pressure (BP) in healthy subjects. To determine the effects of cardiovascular (CV) risk factors on the PLR BP lowering response, we measured brachial artery, systolic (SBP), diastolic (DBP), and pulse pressure (PP) before and 1 minute after 60° PLR, in 125 subjects (58% males, age 48 ± 18 years) with/without CV risk factors/disease. Baseline carotid-radial pulse wave velocity (PWV) and augmentation index (AI) were measured by applanation tonometry. Changes (∆) in SBP and BA PP ranged from +31 to -27 and +35 to -20 mm Hg and were normally distributed. Mean BP decreases upon PLR were ΔSBP -3 ± 9 (P < .001), and ΔPP -2 ± 8 mm Hg (P = .04). On univariate analyses, ΔSBP was correlated with age (r = 0.31, P < .001), PWV (r = 0.53, P < .001), AI (r = 0.25, P < .01), hypertension (r = 0.37, P < .001), hypercholesterolemia (r = 0.25, P < .01) and renal insufficiency (r = 0.19, P = .038). ΔPP was correlated with age (r = 0.31, P < .001), PWV (r = 0.45, P < .001), AI (r = 0.23, P = .01), hypertension (r = 0.22, P = .01), hypercholesterolemia (r = 0.27, P < .001). Multivariate analysis showed PWV the only independent predictor of ΔSBP (B = 3.2, r(2) = 0.40, P < .001) and of ΔPP (B = 2.6, r(2) = 0.36, P < .001). Therefore, changes in SBP and PP induced by PLR are independently and inversely related to carotid-radial PWV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980216"}
{"pmid": "20980231", "title": "Deconstructing self-blame following sexual assault: the critical roles of cognitive content and process.", "content": "Deconstructing self-blame following sexual assault: the critical roles of cognitive content and process. As part of a larger study, predictors of self-blame were investigated in a sample of 149 undergraduate sexual assault survivors. Each participant completed questionnaires regarding their preassault, peritraumatic, and postassault experiences and participated in an individual interview. Results confirmed the central hypothesis that, although several established correlates independently relate to self-blame, only cognitive content and process variables- negative self-cognitions and counterfactual-preventability cognitions-uniquely predict self-blame in a multivariate model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980231"}
{"pmid": "20980229", "title": "Perpetrators of intimate partner sexual violence: are there unique characteristics associated with making partners have sex without a condom?", "content": "Perpetrators of intimate partner sexual violence: are there unique characteristics associated with making partners have sex without a condom? This study examined correlates of making an intimate partner engage in unprotected sex among perpetrators of sexual violence. Based on the Confluence Model, we hypothesized that power and impersonal sex motives would be higher among perpetrators who made a dating partner have unprotected sex. Among a subsample of 78 male college students, significant differences were found for acceptance of verbal pressure, positive attitudes about casual sex, frequency of sexual intercourse, and physical injuries to dating partners. These findings highlight the importance of integrating theories and interventions directed at sexual assault and sexual risk reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980229"}
{"pmid": "20980232", "title": "Domestic violence and sexual assault agency directors' perspectives on services that help survivors.", "content": "Domestic violence and sexual assault agency directors' perspectives on services that help survivors. Community-based domestic violence and sexual assault service providers need sound knowledge regarding services that work well to improve the lives of survivors. This exploratory, qualitative research aimed to help provide such knowledge by investigating domestic violence and sexual assault agency executive directors' ( n = 14) opinions regarding what services are most helpful for survivors. In-depth interviews with directors provided findings about (a) critical services for survivors; (b) essential service delivery practices; (c) ideal services that are challenging to deliver because of funding and other barriers; and (d) areas of service delivery practice uncertainty due to a lack of best practices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980232"}
{"pmid": "20980233", "title": "Telling our stories: the importance of women's narratives of resistance.", "content": "Telling our stories: the importance of women's narratives of resistance. While more research is emerging on women's capacity for successful resistance and the benefits of self-defense training for women, \"resistance\" to the idea of women's resistance remains high. In this note, I describe the importance of bringing true accounts of successful resistance to both academic and lay communities, and the benefits to women of recounting their own experiences of successful resistance to violence and harassment. Such accounts provide new scripts for women's options in responding to violence, mark attempted but thwarted rape as a visible event, and remind women of their own agency in the face of assault.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980233"}
{"pmid": "20980235", "title": "The importance of epistemology: a response to Rosenstein's commentary.", "content": "The importance of epistemology: a response to Rosenstein's commentary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980235"}
{"pmid": "20980234", "title": "Commentary on Jamie L. Callahan's \"Manifestations of power and control: training as the catalyst for scandal at the United States Air Force Academy\".", "content": "Commentary on Jamie L. Callahan's \"Manifestations of power and control: training as the catalyst for scandal at the United States Air Force Academy\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980234"}
{"pmid": "20980237", "title": "Trans-centromere effects on meiotic recombination in the zebrafish.", "content": "Trans-centromere effects on meiotic recombination in the zebrafish. We report that lack of crossover along one chromosome arm is associated with high-frequency occurrence of recombination close to the opposing arm's centromere during zebrafish meiotic recombination. Our data indicate that recombination behavior on the two arms of a chromosome is linked. These results inform mapping strategies for telomeric mutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980237"}
{"pmid": "20980236", "title": "The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant.", "content": "The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant. A cell's ability to tolerate DNA damage is directly connected to the human development of diseases and cancer. To better understand the processes underlying mutagenesis, we studied the cell's reliance on the potentially error-prone translesion synthesis (TLS), and an error-free, template-switching pathway in Saccharomyces cerevisiae. The primary proteins mediating S. cerevisiae TLS are three DNA polymerases (Pols): Rev1, Pol ζ (Rev3/7), and Pol η (Rad30), all with human homologs. Rev1's noncatalytic role in recruiting other DNA polymerases is known to be important for TLS. However, the biological significance of Rev1's unusual conserved DNA polymerase activity, which inserts dC, is much less well understood. Here, we demonstrate that inactivating Rev1's DNA polymerase function sensitizes cells to both chronic and acute exposure to 4-nitroquinoline-1-oxide (4-NQO) but not to UV or cisplatin. Full Rev1-dependent resistance to 4-NQO, however, also requires the additional Rev1 functions. When error-free tolerance is disrupted through deletion of MMS2, Rev1's catalytic activity is more vital for 4-NQO resistance, possibly explaining why the biological significance of Rev1's catalytic activity has been elusive. In the presence or absence of Mms2-dependent error-free tolerance, the catalytic dead strain of Rev1 exhibits a lower 4-NQO-induced mutation frequency than wild type. Furthermore, Pol ζ, but not Pol η, also contributes to 4-NQO resistance. These results show that Rev1's catalytic activity is important in vivo when the cell has to cope with specific DNA lesions, such as N(2)-dG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980236"}
{"pmid": "20980238", "title": "The developmental timing regulator HBL-1 modulates the dauer formation decision in Caenorhabditis elegans.", "content": "The developmental timing regulator HBL-1 modulates the dauer formation decision in Caenorhabditis elegans. Animals developing in the wild encounter a range of environmental conditions, and so developmental mechanisms have evolved that can accommodate different environmental contingencies. Harsh environmental conditions cause Caenorhabditis elegans larvae to arrest as stress-resistant \"dauer\" larvae after the second larval stage (L2), thereby indefinitely postponing L3 cell fates. HBL-1 is a key transcriptional regulator of L2 vs. L3 cell fate. Through the analysis of genetic interactions between mutations of hbl-1 and of genes encoding regulators of dauer larva formation, we find that hbl-1 can also modulate the dauer formation decision in a complex manner. We propose that dynamic interactions between genes that regulate stage-specific cell fate decisions and those that regulate dauer formation promote the robustness of developmental outcomes to changing environmental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980238"}
{"pmid": "20980240", "title": "Socially-responsive gene expression in male Drosophila melanogaster is influenced by the sex of the interacting partner.", "content": "Socially-responsive gene expression in male Drosophila melanogaster is influenced by the sex of the interacting partner. Behavior is influenced by an organism's genes and environment, including its interactions with same or opposite sex individuals. Drosophila melanogaster perform innate, yet socially modifiable, courtship behaviors that are sex specific and require rapid integration and response to multiple sensory cues. Furthermore, males must recognize and distinguish other males from female courtship objects. It is likely that perception, integration, and response to sex-specific cues is partially mediated by changes in gene expression. Reasoning that social interactions with members of either sex would impact gene expression, we compared expression profiles in heads of males that courted females, males that interacted with other males, or males that did not interact with another fly. Expression of 281 loci changes when males interact with females, whereas 505 changes occur in response to male-male interactions. Of these genes, 265 are responsive to encounters with either sex and 240 respond specifically to male-male interactions. Interestingly, 16 genes change expression only when a male courts a female, suggesting that these changes are a specific response to male-female courtship interactions. We supported our hypothesis that socially-responsive genes can function in behavior by showing that egghead (egh) expression, which increases during social interactions, is required for robust male-to-female courtship. We predict that analyzing additional socially-responsive genes will give us insight into genes and neural signaling pathways that influence reproductive and other behavioral interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980240"}
{"pmid": "20980242", "title": "Glycosylation genes expressed in seam cells determine complex surface properties and bacterial adhesion to the cuticle of Caenorhabditis elegans.", "content": "Glycosylation genes expressed in seam cells determine complex surface properties and bacterial adhesion to the cuticle of Caenorhabditis elegans. The surface of the nematode Caenorhabditis elegans is poorly understood but critical for its interactions with the environment and with pathogens. We show here that six genes (bus-2, bus-4, and bus-12, together with the previously cloned srf-3, bus-8, and bus-17) encode proteins predicted to act in surface glycosylation, thereby affecting disease susceptibility, locomotory competence, and sexual recognition. Mutations in all six genes cause resistance to the bacterial pathogen Microbacterium nematophilum, and most of these mutations also affect bacterial adhesion and biofilm formation by Yersinia species, demonstrating that both infection and biofilm formation depend on interaction with complex surface carbohydrates. A new bacterial interaction, involving locomotory inhibition by a strain of Bacillus pumilus, reveals diversity in the surface properties of these mutants. Another biological property--contact recognition of hermaphrodites by males during mating--was also found to be impaired in mutants of all six genes. An important common feature is that all are expressed most strongly in seam cells, rather than in the main hypodermal syncytium, indicating that seam cells play the major role in secreting surface coat and consequently in determining environmental interactions. To test for possible redundancies in gene action, the 15 double mutants for this set of genes were constructed and examined, but no synthetic phenotypes were observed. Comparison of the six genes shows that each has distinctive properties, suggesting that they do not act in a linear pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980242"}
{"pmid": "20980239", "title": "H2A.Z (Htz1) controls the cell-cycle-dependent establishment of transcriptional silencing at Saccharomyces cerevisiae telomeres.", "content": "H2A.Z (Htz1) controls the cell-cycle-dependent establishment of transcriptional silencing at Saccharomyces cerevisiae telomeres. The establishment of transcriptional silencing in Saccharomyces cerevisiae requires progression through the cell cycle. We have previously found that transit through M-phase is necessary and sufficient to establish silencing at telomeres following induction of the Sir3 silencing factor. In this study we find that halting cell-cycle progression in either G(1) or at the beginning of M-phase limits the ability of Sir3 to associate with a telomere-linked reporter gene and prevents the changes in histone modifications associated with gene repression. Deletion of genes coding for the histone variant H2A.Z (Htz1 in yeast) and histone acetyltransferase Sas2 abolish the cell-cycle progression requirement for the establishment of silencing. Cells blocked in telophase (but not at metaphase) are also able to establish silencing. We show that H2A.Z binds to the promoter of our telomere-linked reporter gene and that this binding diminishes in silenced cells. Finally, we observe a specific displacement of H2A.Z from chromatin in telophase-blocked cells, regardless of the silencing status of the reporter gene. These results suggest that the requirement for M-phase in the establishment of silencing may reflect a cell-cycle regulated relaxation of heterochromatin barriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980239"}
{"pmid": "20980243", "title": "Escherichia coli rnlA and rnlB compose a novel toxin-antitoxin system.", "content": "Escherichia coli rnlA and rnlB compose a novel toxin-antitoxin system. RNase LS was originally identified as a potential antagonist of bacteriophage T4 infection. When T4 dmd is defective, RNase LS activity rapidly increases after T4 infection and cleaves T4 mRNAs to antagonize T4 reproduction. Here we show that rnlA, a structural gene of RNase LS, encodes a novel toxin, and that rnlB (formally yfjO), located immediately downstream of rnlA, encodes an antitoxin against RnlA. Ectopic expression of RnlA caused inhibition of cell growth and rapid degradation of mRNAs in ΔrnlAB cells. On the other hand, RnlB neutralized these RnlA effects. Furthermore, overexpression of RnlB in wild-type cells could completely suppress the growth defect of a T4 dmd mutant, that is, excess RnlB inhibited RNase LS activity. Pull-down analysis showed a specific interaction between RnlA and RnlB. Compared to RnlA, RnlB was extremely unstable, being degraded by ClpXP and Lon proteases, and this instability may increase RNase LS activity after T4 infection. All of these results suggested that rnlA-rnlB define a new toxin-antitoxin (TA) system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980243"}
{"pmid": "20980241", "title": "Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae.", "content": "Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae. Purine nucleotides are structural components of the genetic material, function as phosphate donors, participate in cellular signaling, are cofactors in enzymatic reactions, and constitute the main carriers of cellular energy. Thus, imbalances in A/G nucleotide biosynthesis affect nearly the whole cellular metabolism and must be tightly regulated. We have identified a substitution mutation (G388D) that reduces the activity of the GMP synthase Gua1 in budding yeast and the total G-nucleotide pool, leading to precipitous reductions in the GDP/GTP ratio and ATP level in vivo. gua1-G388D strongly reduces the rate of growth, impairs general protein synthesis, and derepresses translation of GCN4 mRNA, encoding a transcriptional activator of diverse amino acid biosynthetic enzymes. Although processing of pre-tRNA(i)(Met) and other tRNA precursors, and the aminoacylation of tRNA(i)(Met) are also strongly impaired in gua1-G388D cells, tRNA(i)(Met)-containing complexes with the macromolecular composition of the eIF2·tRNA(i)(Met.)GTP complex (TC) and the multifactor complex (MFC) required for translation initiation accumulate ∼10-fold in gua1-G388D cells and, to a lesser extent, in wild-type (WT) cells treated with 6-azauracil (6AU). Consistently, addition of an external supply of guanine reverts all the phenotypes of gua1-G388D cells, but not those of gua1-G388D Δhpt1 mutants unable to refill the internal GMP pool through the salvage pathway. These and other findings suggest that a defect in guanine nucleotide biosynthesis evokes a reduction in the rate of general protein synthesis by impairing multiple steps of the process, disrupts the gene-specific reinitiation mechanism for translation of GCN4 mRNA and has far-reaching effects in cell biology and metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980241"}
{"pmid": "20980245", "title": "Forced vital capacity, airway obstruction and survival in a general population sample from the USA.", "content": "Forced vital capacity, airway obstruction and survival in a general population sample from the USA. Many studies show a link between forced expiratory volume in 1 s (FEV(1)) and survival in the general population and this has been interpreted as a link between airway obstruction and survival. However, the observation that vital capacity is also associated with survival weakens this interpretation. Data on spirometry and survival were taken from the Atherosclerosis Risk in Communities (ARIC) limited access dataset. Survival among 7489 participants with usable spirometry and complete data was regressed against measures of ventilatory function after controlling for many other factors likely to be associated with survival. Survival was strongly associated with forced vital capacity (FVC) after adjustment for FEV(1), but not the other way round. The fully adjusted hazard ratio (HR) associated with high FVC was 0.90 in men (95% CI 0.80 to 1.00; p=0.049) and 0.82 in women (95% CI 0.70 to 0.95; p=0.01). This compares with 0.98 for FEV(1) in men (95% CI 0.90 to 1.07; p.0.72) and 1.01 in women (95% CI 0.89 to 1.15; p=0.84). There was no association between survival and airway obstruction as measured by the FEV(1)/FVC ratio. FVC but not airway obstruction predicts survival in asymptomatic adults without chronic respiratory diagnoses or persistent respiratory symptoms. The association is not explained by age, anthropometry, smoking, income occupation or blood pressure. As FVC later in life, cardiovascular risk, type II diabetes mellitus and low-grade systemic inflammation are all associated with poor fetal growth, these other conditions may be partly responsible for the poor survival in those with low FVC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980245"}
{"pmid": "20980244", "title": "Drosophila Mis12 complex acts as a single functional unit essential for anaphase chromosome movement and a robust spindle assembly checkpoint.", "content": "Drosophila Mis12 complex acts as a single functional unit essential for anaphase chromosome movement and a robust spindle assembly checkpoint. The kinetochore is a dynamic multiprotein complex assembled at the centromere in mitosis. Exactly how the structure of the kinetochore changes during mitosis and how its individual components contribute to chromosome segregation is largely unknown. Here we have focused on the contribution of the Mis12 complex to kinetochore assembly and function throughout mitosis in Drosophila. We show that despite the sequential kinetochore recruitment of Mis12 complex subunits Mis12 and Nsl1, the complex acts as a single functional unit. mis12 and nsl1 mutants show strikingly similar developmental and mitotic defects in which chromosomes are able to congress at metaphase, but their anaphase movement is strongly affected. While kinetochore association of Ndc80 absolutely depends on both Mis12 and Nsl1, BubR1 localization shows only partial dependency. In the presence of residual centromeric BubR1 the checkpoint still responds to microtubule depolymerization but is significantly weaker. These observations point to a complexity of the checkpoint response that may reflect subpopulations of BubR1 associated with residual kinetochore components, the core centromere, or elsewhere in the cell. Importantly our results indicate that core structural elements of the inner plate of the kinetochore have a greater contribution to faithful chromosome segregation in anaphase than in earlier stages of mitosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980244"}
{"pmid": "20980246", "title": "Influence of body mass index on outcome of the mechanically ventilated patients.", "content": "Influence of body mass index on outcome of the mechanically ventilated patients. There are limited data on the impact of body mass index on outcomes in mechanically ventilated patients. Secondary analysis of a cohort including 4698 patients mechanically ventilated. Patients were screened daily for management of mechanical ventilation, complications (acute respiratory distress syndrome, sepsis, ventilator associated pneumonia, barotrauma), organ failure (cardiovascular, respiratory, renal, hepatic, haematological) and mortality in the intensive care unit. To estimate the impact of body mass index on acute respiratory distress syndrome and mortality, the authors constructed models using generalised estimating equations (GEE). Patients were evaluated based on their body mass index: 184 patients (3.7%) were underweight, 1995 patients (40%) normal weight, 1781 patients (35.8%) overweight, 792 patients (15.9%) obese and 216 patients (4.3%) severely obese. Severely obese patients were more likely to receive low tidal volume based on actual body weight but high volumes based on predicted body weight. In obese patients, the authors observed a higher incidence of acute respiratory distress syndrome and acute renal failure. After adjustment, the body mass index was significantly associated with the development of acute respiratory distress syndrome: compared with normal weight; OR 1.69 (95% CI 1.07 to 2.69) for obese and OR 2.38 (95% CI 1.15 to 4.89) for severely obese. There were no differences in outcomes (duration of mechanical ventilation, length of stay and mortality in intensive care unit and hospital) based on body mass index categories. In this cohort, obese patients were more likely to have significant complications but there were no associations with increased mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980246"}
{"pmid": "20980247", "title": "Indices of bronchial reactivity and sensitivity.", "content": "Indices of bronchial reactivity and sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980247"}
{"pmid": "20980248", "title": "The potential danger of a solely interferon-gamma release assay-based approach to testing for latent Mycobacterium tuberculosis infection in children.", "content": "The potential danger of a solely interferon-gamma release assay-based approach to testing for latent Mycobacterium tuberculosis infection in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980248"}
{"pmid": "20980249", "title": "Deeper and wider: income and mortality in the USA over three decades.", "content": "Deeper and wider: income and mortality in the USA over three decades. Literature on the socio-economic 'gradient' in health often asserts that income is associated with better health not only for the very poor, but also across the entire income distribution. In addition, changes in the shape of the association between incomes during a period of increasing economic inequality have not been previously studied. The goal of the current study was to estimate and compare the shape of the relationship between income and mortality in the USA for the 1970s, the 1980s and the 1990s. Using income and mortality data from the Panel Study of Income Dynamics for respondents aged 35-64 years, we used a Bayesian Cox Model with regression splines to model the risk of mortality over three 10-year follow-up periods. To identify whether income was more strongly associated with mortality at different parts of the income distribution, we treated income as a linear spline with an unknown knot location. The shape of the association between income and mortality was quite non-linear, with a much stronger association at lower levels of income. The relationship between income and mortality in the USA was also not invariant across time, with the increased risk of death associated with lower income applying to an increasing proportion of the US population over time (9th percentile of income in 1970-79, 20th percentile in 1980-89 and 32nd percentile in 1990-99). Our analyses do not support the claim that income is associated with mortality throughout the income distribution, nor is the association between income and mortality the same across periods. Based on our analyses, a focus on the bottom 30% of the income distribution would seem to return the greatest benefits in reducing socio-economic inequalities in health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980249"}
{"pmid": "20980250", "title": "Structural basis for the interaction between the growth factor-binding protein GRB10 and the E3 ubiquitin ligase NEDD4.", "content": "Structural basis for the interaction between the growth factor-binding protein GRB10 and the E3 ubiquitin ligase NEDD4. In addition to inhibiting insulin receptor and IGF1R kinase activity by directly binding to the receptors, GRB10 can also negatively regulate insulin and IGF1 signaling by mediating insulin receptor and IGF1R degradation through ubiquitination. It has been shown that GRB10 can interact with the C2 domain of the E3 ubiquitin ligase NEDD4 through its Src homology 2 (SH2) domain. Therefore, GRB10 might act as a connector, bringing NEDD4 close to IGF1R to facilitate the ubiquitination of IGF1R by NEDD4. This is the first case in which it has been found that an SH2 domain could colocalize a ubiquitin ligase and its substrate. Here we report the crystal structure of the NEDD4 C2-GRB10 SH2 complex at 2.0 Å. The structure shows that there are three interaction interfaces between NEDD4 C2 and GRB10 SH2. The main interface centers on an antiparallel β-sheet composed of the F β-strand of GRB10 SH2 and the C β-strand of NEDD4 C2. NEDD4 C2 binds at nonclassical sites on the SH2 domain surface, far from the classical phosphotyrosine-binding pocket. Hence, this interaction is phosphotyrosine-independent, and GRB10 SH2 can bind the C2 domain of NEDD4 and the kinase domain of IGF1R simultaneously. Based on these results, a model of how NEDD4 interacts with IGF1R through GRB10 has been proposed. This report provides further evidence that SH2 domains can participate in important signaling interactions beyond the classical recognition of phosphotyrosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980250"}
{"pmid": "20980251", "title": "Mechanisms of autoinhibition of IRF-7 and a probable model for inactivation of IRF-7 by Kaposi's sarcoma-associated herpesvirus protein ORF45.", "content": "Mechanisms of autoinhibition of IRF-7 and a probable model for inactivation of IRF-7 by Kaposi's sarcoma-associated herpesvirus protein ORF45. IRF-7 is the master regulator of type I interferon-dependent immune responses controlling both innate and adaptive immunity. Given the significance of IRF-7 in the induction of immune responses, many viruses have developed strategies to inhibit its activity to evade or antagonize host antiviral responses. We previously demonstrated that ORF45, a KSHV immediate-early protein as well as a tegument protein of virions, interacts with IRF-7 and inhibits virus-mediated type I interferon induction by blocking IRF-7 phosphorylation and nuclear translocation (Zhu, F. X., King, S. M., Smith, E. J., Levy, D. E., and Yuan, Y. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 5573-5578). In this report, we sought to reveal the mechanism underlying the ORF45-mediated inactivation of IRF-7. We found that ORF45 interacts with the inhibitory domain of IRF-7. The most striking feature in the IRF-7 inhibitory domain is two α-helices H3 and H4 that contain many hydrophobic residues and two β-sheets located between the helices that are also very hydrophobic. These hydrophobic subdomains mediate intramolecular interactions that keep the molecule in a closed (inactive) form. Mutagenesis studies confirm the contribution of the hydrophobic helices and sheets to the autoinhibition of IRF-7 in the absence of viral signal. The binding of ORF45 to the critical domain of IRF-7 leads to a hypothesis that ORF45 may maintain the IRF-7 molecule in the closed form and prevent it from being activated in response to viral infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980251"}
{"pmid": "20980252", "title": "Arginine 104 is a key catalytic residue in leukotriene C4 synthase.", "content": "Arginine 104 is a key catalytic residue in leukotriene C4 synthase. Human leukotriene C(4) synthase (hLTC(4)S) is an integral membrane enzyme that conjugates leukotriene (LT) A(4) with glutathione to form LTC(4), a precursor to the cysteinyl leukotrienes (LTC(4), LTD(4), and LTE(4)) that are involved in the pathogenesis of human bronchial asthma. From the crystal structure of hLTC(4)S, Arg-104 and Arg-31 have been implicated in the conjugation reaction. Here, we used site-directed mutagenesis, UV spectroscopy, and x-ray crystallography to examine the catalytic role of Arg-104 and Arg-31. Exchange of Arg-104 with Ala, Ser, Thr, or Lys abolished 94.3-99.9% of the specific activity against LTA(4). Steady-state kinetics of R104A and R104S revealed that the K(m) for GSH was not significantly affected. UV difference spectra of the binary enzyme-GSH complex indicated that GSH ionization depends on the presence of Arg-104 because no thiolate signal, with λ(max) at 239 nm, could be detected using R104A or R104S hLTC(4)S. Apparently, the interaction of Arg-104 with the thiol group of GSH reduces its pK(a) to allow formation of a thiolate anion and subsequent nucleophilic attack at C6 of LTA(4). On the other hand, exchange of Arg-31 with Ala or Glu reduced the catalytic activity of hLTC(4)S by 88 and 70%, respectively, without significantly affecting the k(cat)/K(m) values for GSH, and a crystal structure of R31Q hLTC(4)S (2.1 Å) revealed a Gln-31 side chain pointing away from the active site. We conclude that Arg-104 plays a critical role in the catalytic mechanism of hLTC(4)S, whereas a functional role of Arg-31 seems more elusive. Because Arg-104 is a conserved residue, our results pertain to other homologous membrane proteins and represent a structure-function paradigm probably common to all microsomal GSH transferases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980252"}
{"pmid": "20980253", "title": "Biochemical and structural studies of a HECT-like ubiquitin ligase from Escherichia coli O157:H7.", "content": "Biochemical and structural studies of a HECT-like ubiquitin ligase from Escherichia coli O157:H7. Many microbial pathogens deliver effector proteins via the type III secretion system into infected host cells. Elucidating the function of these effectors is essential for our understanding of pathogenesis. Here, we describe biochemical and structural characterization of an effector protein (NleL) from Escherichia coli O157:H7, a widespread pathogen causing severe foodborne diseases. We show that NleL functionally and structurally mimics eukaryotic HECT E3 ligases and catalyzes formation of unanchored polyubiquitin chains using Lys(6) and Lys(48) linkage. The catalytic cysteine residue forms a thioester intermediate with ubiquitin. The structure of NleL contains two domains, a β-helix domain formed by pentapeptide repeats and a bilobed catalytic domain reminiscent of the N- and C-lobe architecture of HECT E3s. Six structures of NleL observed in two crystal forms revealed a large range of different positions of the C-lobe relative to the N-lobe, indicating that the helix linking the two lobes is extremely flexible. Comparing the structure of NleL with that of the Salmonella homolog SopA showed that the orientation of the C-lobes differ by as much as 108°, suggesting that large movements of the C-lobe may be required to facilitate the transfer of ubiquitin from E2 to the substrate. These results provide critical knowledge toward understanding the molecular mechanism by which pathogens utilize the host ubiquitination system during infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980253"}
{"pmid": "20980254", "title": "Engineered external guide sequences effectively block viral gene expression and replication in cultured cells.", "content": "Engineered external guide sequences effectively block viral gene expression and replication in cultured cells. Ribonuclease P (RNase P) complexed with external guide sequence (EGS) represents a novel nucleic acid-based gene interference approach to modulate gene expression. We have previously used an in vitro selection procedure to generate EGS variants that efficiently direct human RNase P to cleave a target mRNA in vitro. In this study, a variant was used to target the mRNA encoding the protease of human cytomegalovirus (HCMV), which is essential for viral capsid formation and replication. The EGS variant was about 35-fold more active in inducing human RNase P to cleave the mRNA in vitro than the EGS derived from a natural tRNA. Moreover, a reduction of 95% in the expression of the protease and a reduction of 4,000-fold in viral growth were observed in HCMV-infected cells that expressed the EGS variant, whereas a reduction of 80% in the protease expression and an inhibition of 150-fold in viral growth were detected in cells that expressed the EGS derived from a natural tRNA sequence. No significant reduction in viral protease expression or viral growth was observed in cells that either did not express an EGS or produced a \"disabled\" EGS, which carried nucleotide mutations that precluded RNase P recognition. Our results provide direct evidence that engineered EGS variant is highly effective in blocking HCMV expression and growth by targeting the viral protease. Furthermore, these results demonstrate the utility of engineered EGS RNAs in gene targeting applications, including the inhibition of HCMV infection by blocking the expression of virus-encoded essential proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980254"}
{"pmid": "20980255", "title": "Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release.", "content": "Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release. Prostaglandin (PG) E(2), a potent mediator produced in inflamed tissues, can substantially influence mast cell responses including adhesion to basement membrane proteins, chemotaxis, and chemokine production. However, the signaling pathways by which PGE(2) induces mast cell chemotaxis and chemokine production remains undefined. In this study, we identified the downstream target of phosphatidylinositol 3-kinase, mammalian target of rapamycin (mTOR), as a key regulator of these responses. In mouse bone marrow-derived mast cells, PGE(2) was found to induce activation of mTORC1 (mTOR complexed to raptor) as indicated by increased p70S6K and 4E-BP1 phosphorylation, and activation of mTORC2 (mTOR complexed to rictor), as indicated by increased phosphorylation of AKT at position Ser(473). Selective inhibition of the mTORC1 cascade by rapamycin or by the use of raptor-targeted shRNA failed to decrease PGE(2)-mediated chemotaxis or chemokine generation. However, inhibition of the mTORC2 cascade through the dual mTORC1/mTORC2 inhibitor Torin, or through rictor-targeted shRNA, resulted in a significant attenuation in PGE(2)-mediated chemotaxis, which was associated with a comparable decrease in actin polymerization. Furthermore, mTORC2 down-regulation decreased PGE(2)-induced production of the chemokine monocyte chemoattractant protein-1 (CCL2), which was linked to a significant reduction in ROS production. These findings are consistent with the conclusion that activation of mTORC2, downstream of PI3K, represents a critical signaling locus for chemotaxis and chemokine release from PGE(2)-activated mast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980255"}
{"pmid": "20980256", "title": "The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x.", "content": "The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x. Alternative splicing often produces effectors with opposite functions in apoptosis. Splicing decisions must therefore be tightly connected to stresses, stimuli, and pathways that control cell survival and cell growth. We have shown previously that PKC signaling prevents the production of proapoptotic Bcl-x(S) to favor the accumulation of the larger antiapoptotic Bcl-x(L) splice variant in 293 cells. Here we show that the genotoxic stress induced by oxaliplatin elicits an ATM-, CHK2-, and p53-dependent splicing switch that favors the production of the proapoptotic Bcl-x(S) variant. This DNA damage-induced splicing shift requires the activity of protein-tyrosine phosphatases. Interestingly, the ATM/CHK2/p53/tyrosine phosphatases pathway activated by oxaliplatin regulates Bcl-x splicing through the same regulatory sequence element (SB1) that receives signals from the PKC pathway. Convergence of the PKC and DNA damage signaling routes may control the abundance of a key splicing repressor because SB1-mediated repression is lost when protein synthesis is impaired but is rescued by blocking proteasome-mediated protein degradation. The SB1 splicing regulatory module therefore receives antagonistic signals from the PKC and the p53-dependent DNA damage response pathways to control the balance of pro- and antiapoptotic Bcl-x splice variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980256"}
{"pmid": "20980257", "title": "Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily.", "content": "Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily. A thermostable quorum-quenching lactonase from Geobacillus kaustophilus HTA426 (GI: 56420041) was used as an initial template for in vitro directed evolution experiments. This enzyme belongs to the phosphotriesterase-like lactonase (PLL) group of enzymes within the amidohydrolase superfamily that hydrolyze N-acylhomoserine lactones (AHLs) that are involved in virulence pathways of quorum-sensing pathogenic bacteria. Here we have determined the N-butyryl-L-homoserine lactone-liganded structure of the catalytically inactive D266N mutant of this enzyme to a resolution of 1.6 Å. Using a tunable, bioluminescence-based quorum-quenching molecular circuit, the catalytic efficiency was enhanced, and the AHL substrate range increased through two point mutations on the loops at the C-terminal ends of the third and seventh β-strands. This E101N/R230I mutant had an increased value of k(cat)/K(m) of 72-fold toward 3-oxo-N-dodecanoyl-L-homoserine lactone. The evolved mutant also exhibited lactonase activity toward N-butyryl-L-homoserine lactone, an AHL that was previously not hydrolyzed by the wild-type enzyme. Both the purified wild-type and mutant enzymes contain a mixture of zinc and iron and are colored purple and brown, respectively, at high concentrations. The origin of this coloration is suggested to be because of a charge transfer complex involving the β-cation and Tyr-99 within the enzyme active site. Modulation of the charge transfer complex alters the lactonase activity of the mutant enzymes and is reflected in enzyme coloration changes. We attribute the observed enhancement in catalytic reactivity of the evolved enzyme to favorable modulations of the active site architecture toward productive geometries required for chemical catalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980257"}
{"pmid": "20980259", "title": "Molecular basis of reduced glucosylceramidase activity in the most common Gaucher disease mutant, N370S.", "content": "Molecular basis of reduced glucosylceramidase activity in the most common Gaucher disease mutant, N370S. Gaucher disease is caused by the defective activity of the lysosomal hydrolase, glucosylceramidase. Although the x-ray structure of wild type glucosylceramidase has been resolved, little is known about the structural features of any of the >200 mutations. Various treatments for Gaucher disease are available, including enzyme replacement and chaperone therapies. The latter involves binding of competitive inhibitors at the active site to enable correct folding and transport of the mutant enzyme to the lysosome. We now use molecular dynamics, a set of structural analysis tools, and several statistical methods to determine the flexible behavior of the N370S Gaucher mutant at various pH values, with and without binding the chaperone, N-butyl-deoxynojirimycin. We focus on the effect of the chaperone on the whole protein, on the active site, and on three important structural loops, and we demonstrate how the chaperone modifies the behavior of N370S in such a way that it becomes more active at lysosomal pH. Our results suggest a mechanism whereby the binding of N-butyl-deoxynojirimycin helps target correctly folded glucosylceramidase to the lysosome, contributes to binding with saposin C, and explains the initiation of the substrate-enzyme complex. Such analysis provides a new framework for determination of the structure of other Gaucher disease mutants and suggests new approaches for rational drug design.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980259"}
{"pmid": "20980258", "title": "Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L.", "content": "Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L. The natural polyphenol resveratrol (RSV) displays a wide spectrum of health beneficial activities, yet the precise mechanisms remain to be fully elucidated. Here we show that RSV promotes the multimerization and cellular levels of adiponectin in 3T3-L1 adipocytes. The stimulatory effect of RSV was not affected by knocking out Sirt1, but was diminished by suppressing the expression levels of DsbA-L, a recently identified adiponectin-interactive protein that promotes adiponectin multimerization. Suppression of the Akt signaling pathway resulted in an increase in the expression levels of DsbA-L and adiponectin. On the other hand, knocking out FOXO1 or suppressing the activity or expression levels of the AMP-activated protein kinase (AMPK) down-regulated DsbA-L and adiponectin. The stimulatory effect of RSV on adiponectin and DsbA-L expression was completely diminished in FOXO1-suppressed and AMPK-inactivated 3T3-L1 adipocytes. Taken together, our results demonstrate that RSV promotes adiponectin multimerization in 3T3-L1 adipocytes via a Sirt1-independent mechanism. In addition, we show that the stimulatory effect of RSV is regulated by both the Akt/FOXO1 and the AMPK signaling pathways. Last, we show that DsbA-L plays a critical role in the promoting effect of RSV on adiponectin multimerization and cellular levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980258"}
{"pmid": "20980260", "title": "STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.", "content": "STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation. Cytokines produced by islet-infiltrating immune cells induce β-cell apoptosis in type 1 diabetes. The IFN-γ-regulated transcription factors STAT1/IRF-1 have apparently divergent effects on β-cells. Thus, STAT1 promotes apoptosis and inflammation, whereas IRF-1 down-regulates inflammatory mediators. To understand the molecular basis for these differential outcomes within a single signal transduction pathway, we presently characterized the gene networks regulated by STAT1 and IRF-1 in β-cells. This was done by using siRNA approaches coupled to microarray analysis of insulin-producing cells exposed or not to IL-1β and IFN-γ. Relevant microarray findings were further studied in INS-1E cells and primary rat β-cells. STAT1, but not IRF-1, mediates the cytokine-induced loss of the differentiated β-cell phenotype, as indicated by decreased insulin, Pdx1, MafA, and Glut2. Furthermore, STAT1 regulates cytokine-induced apoptosis via up-regulation of the proapoptotic protein DP5. STAT1 and IRF-1 have opposite effects on cytokine-induced chemokine production, with IRF-1 exerting negative feedback inhibition on STAT1 and downstream chemokine expression. The present study elucidates the transcriptional networks through which the IFN-γ/STAT1/IRF-1 axis controls β-cell function/differentiation, demise, and islet inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980260"}
{"pmid": "20980261", "title": "Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling.", "content": "Inhibition of suppressive T cell factor 1 (TCF-1) isoforms in naive CD4+ T cells is mediated by IL-4/STAT6 signaling. The Wnt pathway transcription factor T cell factor 1 (TCF-1) plays essential roles in the control of several developmental processes, including T cell development in the thymus. Although previously regarded as being required only during early T cell development, recent studies demonstrate an important role for TCF-1 in T helper 2 (Th2) cell polarization. TCF-1 was shown to activate expression of the Th2 transcription factor GATA-binding protein 3 (GATA3) and thus to promote the development of IL-4-producing Th2 cells independent of STAT6 signaling. In this study, we show that TCF-1 is down-regulated in human naive CD4(+) T cells cultured under Th2-polarizing conditions. The down-regulation is largely due to the polarizing cytokine IL-4 because IL-4 alone is sufficient to substantially inhibit TCF-1 expression. The IL-4-induced suppression of TCF-1 is mediated by STAT6, as shown by electrophoretic mobility shift assays, chromatin immunoprecipitation, and STAT6 knockdown experiments. Moreover, we found that IL-4/STAT6 predominantly inhibits the shorter, dominant-negative TCF-1 isoforms, which were reported to inhibit IL-4 transcription. Thus, this study provides a model for an IL-4/STAT6-dependent fine tuning mechanism of TCF-1-driven T helper cell polarization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980261"}
{"pmid": "20980263", "title": "X-ray and biochemical analysis of N370S mutant human acid β-glucosidase.", "content": "X-ray and biochemical analysis of N370S mutant human acid β-glucosidase. Gaucher disease is caused by mutations in the enzyme acid β-glucosidase (GCase), the most common of which is the substitution of serine for asparagine at residue 370 (N370S). To characterize the nature of this mutation, we expressed human N370S GCase in insect cells and compared the x-ray structure and biochemical properties of the purified protein with that of the recombinant human GCase (imiglucerase, Cerezyme®). The x-ray structure of N370S mutant acid β-glucosidase at acidic and neutral pH values indicates that the overall folding of the N370S mutant is identical to that of recombinant GCase. Subtle differences were observed in the conformation of a flexible loop at the active site and in the hydrogen bonding ability of aromatic residues on this loop with residue 370 and the catalytic residues Glu-235 and Glu-340. Circular dichroism spectroscopy showed a pH-dependent change in the environment of tryptophan residues in imiglucerase that is absent in N370S GCase. The mutant protein was catalytically deficient with reduced V(max) and increased K(m) values for the substrate p-nitrophenyl-β-D-glucopyranoside and reduced sensitivity to competitive inhibitors. N370S GCase was more stable to thermal denaturation and had an increased lysosomal half-life compared with imiglucerase following uptake into macrophages. The competitive inhibitor N-(n-nonyl)deoxynojirimycin increased lysosomal levels of both N370S and imiglucerase 2-3-fold by reducing lysosomal degradation. Overall, these data indicate that the N370S mutation results in a normally folded but less flexible protein with reduced catalytic activity compared with imiglucerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980263"}
{"pmid": "20980262", "title": "Single domain intracellular antibodies from diverse libraries: emphasizing dual functions of LMO2 protein interactions using a single VH domain.", "content": "Single domain intracellular antibodies from diverse libraries: emphasizing dual functions of LMO2 protein interactions using a single VH domain. Interfering intracellular antibodies are valuable for biological studies as drug surrogates and as potential macromolecular drugs per se. Their application is still limited because of the difficulty of acquisition of functional intracellular antibodies. We describe the use of the new intracellular antibody capture procedure (IAC(3)) to facilitate direct isolation of functional single domain antibody fragments using four independent target molecules (LMO2, TP53, CRAF1, and Hoxa9) from a set of diverse libraries. Initially, these have variability in only one of the three antigen-binding CDR regions of VH or VL and first round single domains are affinity matured by iterative randomization of the two other CDRs and reselection. We highlight the approach using a single domain binding to LMO2 protein. Our results show that interfering with LMO2 protein function demonstrates a role specifically in erythroid differentiation, confirm a necessary and sufficient function for LMO2 as a cancer therapy target in T-cell neoplasia and allowed for the first time production of soluble recombinant LMO2 protein by co-expression with intracellular domain antibodies. Co-crystallization of LMO2 and the anti-LMO2 VH protein was successful. These results demonstrate that this third generation IAC(3) offers a robust toolbox for various biomedical applications and consolidates functional features of the LMO2 protein complex, which includes the importance of Lmo2-Ldb1 protein interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980262"}
{"pmid": "20980265", "title": "Surprising substrate versatility in SLC5A6: Na+-coupled I- transport by the human Na+/multivitamin transporter (hSMVT).", "content": "Surprising substrate versatility in SLC5A6: Na+-coupled I- transport by the human Na+/multivitamin transporter (hSMVT). Iodide (I(-)) is an essential constituent of the thyroid hormones triiodothyronine and thyroxine, which are required for the development of the central nervous system in the fetus and newborn. I(-) uptake in the thyroid is mediated by the Na(+)/I(-) symporter (NIS). NIS has gained particular medical interest due to its sensitivity to the environmental pollutant perchlorate (ClO(4)(-)) and its implication in radioiodide cancer treatment. Recently, others have shown that I(-) absorption in the intestine is mediated by NIS (Nicola, J. P., Basquin, C., Portulano, C., Reyna-Neyra, A., Paroder, M., and Carrasco, N. (2009) Am. J. Physiol. Cell Physiol. 296, C654-662). However, their data suggest the participation of other systems in the homeostasis of I(-), in particular because in vivo uptake studies revealed a ClO(4)(-)-insensitive transport component. Here, we describe Na(+)-coupled I(-) uptake by the human Na(+)/multivitamin transporter (hSMVT), a related protein isolated from the placenta, where it was suggested to supply the fetus with the water-soluble vitamins biotin and pantothenic acid, and α-lipoic acid. hSMVT-mediated Na(+)/I(-) symport is inhibited by the other three organic hSMVT substrates but not by NIS substrates; notably, hSMVT is insensitive to ClO(4)(-). Because hSMVT is found in the intestine and in many other tissues, we propose that hSMVT may play an important role in the homeostasis of I(-) in the body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980265"}
{"pmid": "20980264", "title": "TNF-alpha induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells.", "content": "TNF-alpha induces macroautophagy and regulates MHC class II expression in human skeletal muscle cells. Macroautophagy, a homeostatic process that shuttles cytoplasmic constituents into endosomal and lysosomal compartments, has recently been shown to deliver antigens for presentation on major histocompatibility complex (MHC) class II molecules. Skeletal muscle fibers show a high level of constitutive macroautophagy and express MHC class II molecules upon immune activation. We found that tumor necrosis factor-α (TNF-α), a monokine overexpressed in inflammatory myopathies, led to a marked up-regulation of macroautophagy in skeletal myocytes. Furthermore, TNF-α augmented surface expression of MHC class II molecules in interferon-γ (IFN-γ)-treated myoblasts. The synergistic effect of TNF-α and IFN-γ on the induction of MHC class II surface expression was not reflected by higher intracellular human leukocyte antigen (HLA)-DR levels and was reversed by macroautophagy inhibition, suggesting that TNF-α facilitates antigen processing via macroautophagy for more efficient MHC class II loading. Muscle biopsies from patients with sporadic inclusion body myositis, a well defined myopathy with chronic inflammation, showed that over 20% of fibers that contained autophagosomes costained for MHC class II molecules and that more than 40% of double-positive muscle fibers had contact with CD4(+) and CD8(+) immune cells. These findings establish a mechanism through which TNF-α regulates both macroautophagy and MHC class II expression and suggest that macroautophagy-mediated antigen presentation contributes to the immunological environment of the inflamed human skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980264"}
{"pmid": "20980266", "title": "Bacillus subtilis CwlP of the SP-{beta} prophage has two novel peptidoglycan hydrolase domains, muramidase and cross-linkage digesting DD-endopeptidase.", "content": "Bacillus subtilis CwlP of the SP-{beta} prophage has two novel peptidoglycan hydrolase domains, muramidase and cross-linkage digesting DD-endopeptidase. For bacteria and bacteriophages, cell wall digestion by hydrolases is a very important event. We investigated one of the proteins involved in cell wall digestion, the yomI gene product (renamed CwlP). The gene is located in the SP-β prophage region of the Bacillus subtilis chromosome. Inspection of the Pfam database indicates that CwlP contains soluble lytic transglycosylase (SLT) and peptidase M23 domains, which are similar to Escherichia coli lytic transglycosylase Slt70, and the Staphylococcus aureus Gly-Gly endopeptidase LytM, respectively. The SLT domain of CwlP exhibits hydrolytic activity toward the B. subtilis cell wall; however, reverse phase (RP)-HPLC and mass spectrometry revealed that the CwlP-SLT domain has only muramidase activity. In addition, the peptidase M23 domain of CwlP exhibited hydrolytic activity and could cleave d-Ala-diaminopimelic acid cross-linkage, a property associated with dd-endopeptidases. Remarkably, the M23 domain of CwlP possessed a unique Zn(2+)-independent endopeptidase activity; this contrasts with all other characterized M23 peptidases (and enzymes similar to CwlP), which are Zn(2+) dependent. Both domains of CwlP could hydrolyze the peptidoglycan and cell wall of B. subtilis. However, the M23 domain digested neither the peptidoglycans nor the cell walls of S. aureus or Streptococcus thermophilus. The effect of defined point mutations in conserved amino acid residues of CwlP is also determined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980266"}
{"pmid": "20980267", "title": "Decoding toxicity: deducing the sequence requirements of IbsC, a type I toxin in Escherichia coli.", "content": "Decoding toxicity: deducing the sequence requirements of IbsC, a type I toxin in Escherichia coli. Bacterial genomes encode a collection of small peptides that are deleterious to their hosts when overexpressed. The physiological relevance of the majority of these peptides is unknown at present, although many of them have been implicated in regulatory processes important for cell survival and adaptability. One peptide that is of particular interest to us is a 19-amino acid proteic toxin, coined IbsC, whose production is repressed by SibC, an RNA antitoxin. Together, IbsC and SibC constitute a type I toxin-antitoxin (TA) pair. To better understand the function of IbsC and to decipher the sequence determinants for its toxic phenotype, we carried out extensive sequence analyses of the peptide. We generated a series of truncation and single amino acid deletion mutants to determine the minimal sequence required for toxicity. We further probed into functionally relevant amino acids with a comprehensive set of IbsC mutants produced using a systematic sequence randomization strategy. We found that IbsC remained toxic in the presence of multiple deletions and single amino acid substitutions, despite being well-conserved in Escherichia coli and across other Gram-negative bacteria. The toxicity of this peptide was determined to be dependent on a stretch of highly hydrophobic residues near its center. Our results defined sequence-function relationship of IbsC and offered additional insights into properties common to membrane-targeting type I toxins in E. coli and related species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980267"}
{"pmid": "20980268", "title": "Remodeling of the major light-harvesting antenna protein of PSII protects the young leaves of barley (Hordeum vulgare L.) from photoinhibition under prolonged iron deficiency.", "content": "Remodeling of the major light-harvesting antenna protein of PSII protects the young leaves of barley (Hordeum vulgare L.) from photoinhibition under prolonged iron deficiency. Because of the high demand for iron of the photosynthetic apparatus in thylakoid membranes, iron deficiency primarily affects the electron transfer between the two photosystems (PSI and PSII), resulting in photooxidative damage in plants. However, in barley, PSII is protected against photoinhibition, and the plant survives even with a low iron content in its chlorotic leaves. In this study, we report an adaptation mechanism of the photosynthetic apparatus in barley to iron deficiency, which is concomitant with the remodeling of a PSII antenna system. Transcriptome analysis revealed that long-term iron deficiency induced the expression of two genes of the major light-harvesting Chl a/b-binding protein of PSII (LHCII), namely HvLhcb1.11 and HvLhcb1.12. Chl fluorescence analysis of the wild type and Lhcb1-less chlorina mutants clearly showed that non-photochemical quenching (NPQ) of the wild type was increased by approximately 200% by iron deficiency, whereas NPQ of chlorina mutants did not change significantly under iron deficiency. The mutant showed severe photodamage in young leaves under prolonged iron deficiency, suggesting that the HvLhcb1 protein is essential for both thermal dissipation and photoprotection in iron-deficient barley. Analysis of thylakoid protein complexes revealed that the proportion of the monomeric form of Lhcb1 significantly increased in barley grown under iron-deficient conditions. We hypothesize that alteration of the HvLhcb1 subpopulations modifies the organization of LHCII in the thylakoid membranes, which is a key step for thermal dissipation to compensate for excess excitation energy and thereby protect the photosystems from serious damage in iron-deficient barley leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980268"}
{"pmid": "20980269", "title": "Efficient yeast one-/two-hybrid screening using a library composed only of transcription factors in Arabidopsis thaliana.", "content": "Efficient yeast one-/two-hybrid screening using a library composed only of transcription factors in Arabidopsis thaliana. Yeast one-hybrid screening is widely used for the identification of transcription factors (TFs) that interact with specific DNA sequences. However, screening a whole cDNA library is not efficient for the identification of TFs because TF genes represent only a small percentage of clones in a cDNA library. Here, we present the development of an efficient yeast one-hybrid screening system using a prey library composed only of approximately 1,500 TF cDNAs of Arabidopsis thaliana. This library enabled us to isolate a TF that binds to a specific promoter sequence with high efficiency, even when the promoter region of the gene of interest was directly employed as bait. Furthermore, this library was also successfully applied as a yeast two-hybrid library to find TFs that interact with specific proteins. This efficient system will contribute to the elucidation of gene regulatory networks in plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980269"}
{"pmid": "20980271", "title": "Optimized data fusion for K-means Laplacian clustering.", "content": "Optimized data fusion for K-means Laplacian clustering. We propose a novel algorithm to combine multiple kernels and Laplacians for clustering analysis. The new algorithm is formulated on a Rayleigh quotient objective function and is solved as a bi-level alternating minimization procedure. Using the proposed algorithm, the coefficients of kernels and Laplacians can be optimized automatically. Three variants of the algorithm are proposed. The performance is systematically validated on two real-life data fusion applications. The proposed Optimized Kernel Laplacian Clustering (OKLC) algorithms perform significantly better than other methods. Moreover, the coefficients of kernels and Laplacians optimized by OKLC show some correlation with the rank of performance of individual data source. Though in our evaluation the K values are predefined, in practical studies, the optimal cluster number can be consistently estimated from the eigenspectrum of the combined kernel Laplacian matrix. The MATLAB code of algorithms implemented in this paper is downloadable from http://homes.esat.kuleuven.be/~sistawww/bioi/syu/oklc.html.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980271"}
{"pmid": "20980272", "title": "Identification of subfamily-specific sites based on active sites modeling and clustering.", "content": "Identification of subfamily-specific sites based on active sites modeling and clustering. Current computational approaches to function prediction are mostly based on protein sequence classification and transfer of annotation from known proteins to their closest homologous sequences relying on the orthology concept of function conservation. This approach suffers a major weakness: annotation reliability depends on global sequence similarity to known proteins and is poorly efficient for enzyme superfamilies that catalyze different reactions. Structural biology offers a different strategy to overcome the problem of annotation by adding information about protein 3D structures. This information can be used to identify amino acids located in active sites, focusing on detection of functional polymorphisms residues in an enzyme superfamily. Structural genomics programs are providing more and more novel protein structures at a high-throughput rate. However, there is still a huge gap between the number of sequences and available structures. Computational methods, such as homology modeling provides reliable approaches to bridge this gap and could be a new precise tool to annotate protein functions. Here, we present Active Sites Modeling and Clustering (ASMC) method, a novel unsupervised method to classify sequences using structural information of protein pockets. ASMC combines homology modeling of family members, structural alignment of modeled active sites and a subsequent hierarchical conceptual classification. Comparison of profiles obtained from computed clusters allows the identification of residues correlated to subfamily function divergence, called specificity determining positions. ASMC method has been validated on a benchmark of 42 Pfam families for which previous resolved holo-structures were available. ASMC was also applied to several families containing known protein structures and comprehensive functional annotations. We will discuss how ASMC improves annotation and understanding of protein families functions by giving some specific illustrative examples on nucleotidyl cyclases, protein kinases and serine proteases. http://www.genoscope.fr/ASMC/.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980272"}
{"pmid": "20980270", "title": "Molecular basis of the core regulatory network in ABA responses: sensing, signaling and transport.", "content": "Molecular basis of the core regulatory network in ABA responses: sensing, signaling and transport. ABA is a major phytohormone that regulates a broad range of plant traits and is especially important for adaptation to environmental conditions. Our understanding of the molecular basis of ABA responses in plants improved dramatically in 2009 and 2010, banner years for ABA research. There are three major components; PYR/PYL/ RCAR (an ABA receptor), type 2C protein phosphatase (PP2C; a negative regulator) and SNF1-related protein kinase 2 (SnRK2; a positive regulator), and they offer a double negative regulatory system, [PYR/PYL/RCAR-| PP2C-| SnRK2]. In the absence of ABA, PP2C inactivates SnRK2 by direct dephosphorylation. In response to environmental or developmental cues, ABA promotes the interaction of PYR/PYL/RCAR and PP2C, resulting in PP2C inhibition and SnRK2 activation. This signaling complex can work in both the nucleus and cytosol, as it has been shown that SnRK2 phosphorylates basic-domain leucine zipper (bZIP) transcription factors or membrane proteins. Several structural analyses of PYR/PYL/RCAR have provided the mechanistic basis for this 'core signaling' model, by elucidating the mechanism of ABA binding of receptors, or the 'gate-latch-lock' mechanism of interaction with PP2C in inhibiting activity. On the other hand, intercellular ABA transport had remained a major issue, as had intracellular ABA signaling. Recently, two plasma membrane-type ABC transporters were identified and shed light on the influx/efflux system of ABA, resolving how ABA is transported from cell to cell in plants. Our knowledge of ABA responses in plants has been greatly expanded from intracellular signaling to intercellular transport of ABA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980270"}
{"pmid": "20980273", "title": "Reconceptualising health services for school-age children in the 21st century.", "content": "Reconceptualising health services for school-age children in the 21st century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980273"}
{"pmid": "20980275", "title": "A knotted problem.", "content": "A knotted problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980275"}
{"pmid": "20980278", "title": "Archimedes. Question 1. Does oral ondansetron reduce vomiting and the need for intravenous fluids and hospital admission in children presenting with vomiting secondary to gastroenteritis?", "content": "Archimedes. Question 1. Does oral ondansetron reduce vomiting and the need for intravenous fluids and hospital admission in children presenting with vomiting secondary to gastroenteritis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980278"}
{"pmid": "20980277", "title": "The neurodevelopmental sequelae of childhood leukaemia and its treatment.", "content": "The neurodevelopmental sequelae of childhood leukaemia and its treatment. The overall survival of childhood leukaemia has increased dramatically over recent decades. With the increasing number of survivors, chemotherapy protocols are designed not only to improve cure rates but also to minimise long-term sequelae. Central-nervous-system-directed therapy given as intrathecal chemotherapy and/or cranial irradiation plays a crucial part in acute leukaemia treatment but can also result in adverse effects on the developing brain. The elimination of cranial irradiation from current treatment protocols has improved the neurocognitive outcome without compromising survival rates. Although neurodevelopmental long-term sequelae after chemotherapy-only central-nervous-system-directed therapies may be more subtle, survivors of childhood leukaemia will continue to require methodical follow-up and appropriate rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980277"}
{"pmid": "20980279", "title": "Archimedes. Towards evidence based medicine for paediatricians.", "content": "Archimedes. Towards evidence based medicine for paediatricians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980279"}
{"pmid": "20980280", "title": "Archimedes. Question 2. Is oral montelukast beneficial in treating acute asthma exacerbations in children?", "content": "Archimedes. Question 2. Is oral montelukast beneficial in treating acute asthma exacerbations in children?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980280"}
{"pmid": "20980274", "title": "Perinatal interventions and survival in resource-poor settings: which work, which don't, which have the jury out?", "content": "Perinatal interventions and survival in resource-poor settings: which work, which don't, which have the jury out? Perinatal conditions make the largest contribution to the burden of disease in low-income countries. Although postneonatal mortality rates have declined, stillbirth and early neonatal mortality rates remain high in many countries in Africa and Asia, and there is a concentration of mortality around the time of birth. Our article begins by considering differences in the interpretation of 'intervention' to improve perinatal survival. We identify three types of a single action, a collection of actions delivered in a package and a broader social or system approach. We use this classification to summarise the findings of recent systematic reviews and meta-analyses. After describing the growing evidence base for the effectiveness of community-based perinatal care, we discuss current concerns about integration: of women's and children's health programmes, of community-based and institutional care, and of formal and informal sector human resources. We end with some thoughts on the complexity of choices confronting women and their families in low-income countries, particularly in view of the growth in non-government and private sector healthcare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980274"}
{"pmid": "20980281", "title": "Archimedes. Question 3. Should carbamazepine be administered to manage agitation and aggressive behaviour following paediatric acquired brain injury?", "content": "Archimedes. Question 3. Should carbamazepine be administered to manage agitation and aggressive behaviour following paediatric acquired brain injury?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980281"}
{"pmid": "20980282", "title": "No overall progression and occasional repair of erosions despite persistent inflammation in adalimumab-treated rheumatoid arthritis patients: results from a longitudinal comparative MRI, ultrasonography, CT and radiography study.", "content": "No overall progression and occasional repair of erosions despite persistent inflammation in adalimumab-treated rheumatoid arthritis patients: results from a longitudinal comparative MRI, ultrasonography, CT and radiography study. To monitor joint inflammation and destruction in rheumatoid arthritis (RA) patients receiving adalimumab/methotrexate combination therapy using MRI and ultrasonography. To assess the predictive value of MRI and ultrasonography for erosive progression on CT and compare MRI/ultrasonography/radiography for erosion detection/monitoring. Fifty-two erosive biological-naive RA patients were followed with repeated MRI/ultrasonography/radiography (0/6/12 months) and clinical/biochemical assessments during adalimumab/methotrexate combination therapy. No overall erosion progression or repair was observed at 6 or 12 months (Wilcoxon; p > 0.05), but erosion progressors and regressors were observed using the smallest detectable change cut-off. Scores of MRI synovitis, grey-scale synovitis (GSS) and power Doppler ultrasonography decreased after 6 and 12 months (p < 0.05), as did DAS28, HAQ and tender and swollen joint counts (p < 0.001). Patients with progression on CT had higher baseline MRI bone oedema scores. The RR for CT progression in bones with versus without baseline MRI bone oedema was 3.8 (95% CI 1.5 to 9.3) and time-integrated MRI bone oedema, power Doppler and GSS scores were higher in bones/joints with CT progression (Mann-Whitney; p < 0.05). With CT as the reference method, sensitivities/specificities for erosion in metacarpophalangeal joints were 68%/92%, 44%/95% and 26%/98% for MRI, ultrasonography and radiography, respectively. Median intraobserver correlation coefficient was 0.95 (range 0.44-0.99). During adalimumab/methotrexate combination therapy, no overall erosive progression or repair occurred, whereas repair of individual erosions was documented on MRI, and MRI and ultrasonography synovitis decreased. Inflammation on MRI and ultrasonography, especially MRI bone oedema, was predictive for erosive progression on CT, at bone/joint level and MRI bone oedema also at patient level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980282"}
{"pmid": "20980284", "title": "Elevated number of recently activated T cells in bone marrow of patients with rheumatoid arthritis: a role for interleukin 15?", "content": "Elevated number of recently activated T cells in bone marrow of patients with rheumatoid arthritis: a role for interleukin 15? (1) To compare the absolute T-cell numbers in bone marrow (BM) isolated from patients with rheumatoid arthritis (RA) and osteoarthritis (OA); (2) to measure the levels of soluble interleukin 15 (IL-15) and IL-7; (3) to analyse the expression of activation markers on T cells; (4) to analyse influence of IL-15 stimulation on T-cell proliferation. BM samples were obtained from patients undergoing joint replacement surgery. Concentrations of IL-15 and IL-7 were measured using specific ELISAs. The absolute number of T lymphocytes, their activation status and proliferation were evaluated by flow cytometry. BM from patients with RA contained double the number of CD3 T cells in comparison with OA (6.1 vs 2.7 × 10(6) cells/ml, p<0.008). Ratio CD3CD4:CD3CD8 was increased in RA BM, clearly indicating accumulation of CD3CD4 cells. T cells obtained from patients with RA expressed higher level of early activation markers than from OA. Elevated levels of IL-15 were found in BM plasma from patients with RA in comparison with patients with OA (1304.5±956.3 pg/ml and 760±238.7 pg/ml respectively, p<0.01). These data were confirmed by immunohistochemistry of RA BM from regions proximal and distal to the joint. Although both CD3CD4 and CD3CD8 cells proliferated after IL-15 stimulation in vitro, CD3CD4 cells from patients with RA proliferated more vigorously than those from patients with OA, reflecting the composition of T-cell subsets in BM. These results suggest that locally overproduced IL-15 may be responsible for the activation and proliferation of T cells in situ, reflected by significantly increased number of activated T cells in RA BM, possibly contributing to the pathogenesis of RA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980284"}
{"pmid": "20980285", "title": "Improvement of HbA1c during treatment with humanised anti-interleukin 6 receptor antibody, tocilizumab.", "content": "Improvement of HbA1c during treatment with humanised anti-interleukin 6 receptor antibody, tocilizumab.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980285"}
{"pmid": "20980283", "title": "The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype.", "content": "The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype. Increased expression of type I IFN genes, also referred to as an IFN signature, has been detected in various autoimmune diseases including rheumatoid arthritis (RA). Interferon regulatory factors, such as IRF5, coordinate type I IFN expression. Multiple IRF5 variants were suggested as autoimmunity susceptibility factors. As the linkage proof remains important to establish fully any genetic RA susceptibility factor, the authors took advantage of the largest reported European trio family resource dedicated to RA to test for linkage IRF5 and performed a genotype-phenotype analysis. 1140 European Caucasian individuals from 380 RA trio families were genotyped for IRF5 rs3757385, rs2004640 and rs10954213 single nucleotide polymorphisms (SNP). Single marker analysis provided linkage evidence for each IRF5 SNP investigated. IRF5 linked to RA with two haplotypes: the CTA risk haplotype 'R' (transmission (T)=60.6%, p=23.1×10(-5)) and the AGG protective haplotype 'P' (T=39.6%, p=0.0015). Linkage was significantly stronger in non-erosive disease for both IRF5 R and P haplotypes (T=73.9%, p=4.20×10(-5) and T=19.6%, p=3.66×10(-5), respectively). Multivariate logistic regression analysis found IRF5 linked to RA independently of the rheumatoid factor status. IRF5 RR and PP haplotypic genotypes were associated with RA, restricted to the non-erosive phenotype: p=1.68×10(-4), OR 4.80, 95% CI 2.06 to 11.19; p=0.003, OR 0.17, 95% CI 0.05 to 0.57, respectively. This study provides the 'association and linkage proof' establishing IRF5 as a RA susceptibility gene and the identification of a genetic factor that seems to contribute to the modulation of the erosive phenotype. Further studies are warranted to clarify the role of IRF5 in RA and its subphenotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980283"}
{"pmid": "20980286", "title": "Urinary type II collagen C-terminal peptide is associated with synovitis and predicts structural bone loss in very early inflammatory arthritis.", "content": "Urinary type II collagen C-terminal peptide is associated with synovitis and predicts structural bone loss in very early inflammatory arthritis. In rheumatoid arthritis, high levels of the cartilage turnover biomarker C-terminal cross-linking telopeptide of type II collagen (CTX-II) predict an increased risk of radiological progression. In very early inflammatory arthritis erosions are uncommon, therefore CTX-II requires validation against early markers of inflammatory arthritis such as power Doppler ultrasound (PDUS) synovitis and bone mineral density (BMD) loss. In 50 subjects with 12 weeks or less of inflammatory hand symptoms, urinary CTX-II and PDUS were performed at baseline and hand BMD at baseline and 12 months. CTX-II data were log transformed to a normal distribution. Associations between variables were examined using Pearson's r/Spearman's ρ correlations. The mean 12- month change in BMD was -0.0068 g/cm² and the geometric mean for baseline CTX-II/creatinine was 245.89 ng/mmol. Log-transformed baseline CTX-II showed a substantive negative association with change in average BMD over 12 months, controlling for baseline BMD and erythrocyte sedimentation rate (r=-0.359, p=0.044). The median total PDUS score was 3.0 and baseline CTX-II was significantly associated with baseline total PDUS (Spearman's ρ=0.482, p=0.002). Urinary CTX-II correlates with PDUS synovitis and hand BMD reduction very early in the course of inflammatory arthritis, suggesting that CTX-II has potential as a biomarker in very early inflammatory arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980286"}
{"pmid": "20980287", "title": "Changes in hip fracture rate before and after total knee replacement due to osteoarthritis: a population-based cohort study.", "content": "Changes in hip fracture rate before and after total knee replacement due to osteoarthritis: a population-based cohort study. Patients with knee osteoarthritis have an increase in bone mass but no corresponding decrease in risk of fracture. This study describes the rates of hip fracture in subjects with knee osteoarthritis before and after having a total knee replacement (TKR), compared with matched controls. A population-based prospective cohort study was conducted. The study population included, from the General Practice Research Database (UK), patients 40 years and older, undergoing TKR between 1986 and end-2006 for knee osteoarthritis as 'cases' (n=20,033). Five disease-free controls (n=100,165) were randomly selected, and matched for age, gender and practice. Hip fractures were ascertained using READ codes, and yearly rates of hip fracture and rate differences were calculated for the 5 years before and after surgery, using Poisson regression. Stratified analyses were performed by age and history of fracture. Hip fracture rates were non-significantly reduced compared with controls before the operation. In the year after TKR, risk increased significantly (RR 1.58; 95% CI 1.14 to 2.19). Rates then declined to equal those of controls by 3 years, and continued decreasing until the end of follow-up; corresponding RR were not significant. The increased risk is greatest in younger ages and in those without previous fracture. The association between knee osteoarthritis and fractures is time-dependent, which may explain the current controversy in the literature. The association is also modified by TKR: subjects have a higher rate of hip fracture than matched controls after TKR, although the rates may eventually decrease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980287"}
{"pmid": "20980290", "title": "Total laparoscopic hysterectomy without general anesthesia.", "content": "Total laparoscopic hysterectomy without general anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980290"}
{"pmid": "20980288", "title": "Benefits of massive weight loss on symptoms, systemic inflammation and cartilage turnover in obese patients with knee osteoarthritis.", "content": "Benefits of massive weight loss on symptoms, systemic inflammation and cartilage turnover in obese patients with knee osteoarthritis. To investigate the effect of massive weight loss on (1) knee pain and disability, (2) low-grade inflammation and metabolic status and (3) joint biomarkers in obese patients with knee osteoarthritis (OA). 140 patients involved in a gastric surgery programme were screened for painful knee OA, and 44 were included (age 44 ± 10.3 years, body mass index (BMI) 50.7 ± 7.2 kg/m(2)). Clinical data and biological samples were collected before and 6 months after surgery. Before surgery, interleukin 6 (IL-6) levels were correlated with levels of high-sensitivity C reactive protein (hsCRP) (p=0.006) and Helix-II (p=0.01), a biomarker of cartilage turnover, and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) function score (p=0.03). Surgery resulted in substantial decrease in BMI (-20%). Levels of insulin and insulin resistance were decreased at 6 months. Knee pain decreased after surgery (24.5 ± 21 mm vs 50 ± 26.6 mm; p<0.001), and scores on all WOMAC subscales were improved. Levels of IL-6 (p<0.0001), hsCRP (p<0.0001), orosomucoid (p<0.0001) and fibrinogen (p=0.04) were decreased after surgery. Weight loss resulted in a significant increase in N-terminal propeptide of type IIA collagen levels (+32%; p=0.002), a biomarker of cartilage synthesis, and a significant decrease in cartilage oligomeric matrix protein (COMP) (-36%; p<0.001), a biomarker of cartilage degradation. Changes in COMP concentration were correlated with changes in insulin levels (p=0.02) and insulin resistance (p=0.05). Massive weight loss improves pain and function and decreases low-grade inflammation. Change in levels of joint biomarkers with weight loss suggests a structural effect on cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980288"}
{"pmid": "20980289", "title": "Ethylene stimulation of latex yield depends on the expression of a sucrose transporter (HbSUT1B) in rubber tree (Hevea brasiliensis).", "content": "Ethylene stimulation of latex yield depends on the expression of a sucrose transporter (HbSUT1B) in rubber tree (Hevea brasiliensis). Hevea brasiliensis is an important industrial crop for natural rubber production. Latex biosynthesis occurs in the cytoplasm of highly specialized latex cells and requires sucrose as the unique precursor. Ethylene stimulation of latex production results in high sugar flow from the surrounding cells of inner bark towards the latex cells. The aim of this work was to understand the role of seven sucrose transporters (HbSUTs) and one hexose transporter (HbHXT1) in this process. Two Hevea clones were used: PB217 and PB260, respectively described as high and low yielding clones. The expression pattern of these sugar transporters (HbSUTs and HbHXT1) was monitored under different physiological conditions and found to be maximal in latex cells. HbSUT1, one of the most abundant isoforms, displayed the greatest response to ethylene treatment. In clone PB217, ethylene treatment led to a higher accumulation of HbSUT1B in latex cells than in the inner bark tissues. Conversely, stronger expression of HbSUT1B was observed in inner bark tissues than in latex cells of PB260. A positive correlation with HbSUT1B transcript accumulation and increased latex production was further supported by its lower expression in latex cells of the virgin clone PB217.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980289"}
{"pmid": "20980291", "title": "Evidence for genetically influenced caste determination in phylogenetically diverse species of the termite genus Reticulitermes.", "content": "Evidence for genetically influenced caste determination in phylogenetically diverse species of the termite genus Reticulitermes. A number of social insect species have recently been shown to have genetically influenced caste determination (GCD), challenging the conventional view that caste determination should be strictly environmental. To date, GCD has been found in phylogenetically isolated species; examples of GCD being present in multiple species of a genus are lacking. Through crossing experiments of neotenic (juvenile) reproductives, we have recently provided the first evidence for a royal versus worker GCD in the termite Reticulitermes speratus. To elucidate whether this system is more widespread, we performed crossing experiments using three additional Reticulitermes species. Offspring caste and sex ratios were found to be highly similar to those found previously in R. speratus, raising the possibility that GCD was present in an ancestral lineage of Reticulitermes, and subsequently maintained throughout several episodes of speciation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980291"}
{"pmid": "20980292", "title": "Dietary protein content affects evolution for body size, body fat and viability in Drosophila melanogaster.", "content": "Dietary protein content affects evolution for body size, body fat and viability in Drosophila melanogaster. The ability to use different food sources is likely to be under strong selection if organisms are faced with natural variation in macro-nutrient (protein, carbohydrate and lipid) availabilities. Here, we use experimental evolution to study how variable dietary protein content affects adult body composition and developmental success in Drosophila melanogaster. We reared flies on either a standard diet or a protein-enriched diet for 17 generations before testing them on both diet types. Flies from lines selected on protein-rich diet produced phenotypes with higher total body mass and relative lipid content when compared with those selected on a standard diet, irrespective of which of the two diets they were tested on. However, selection on protein-rich diet incurred a cost as flies reared on this diet had markedly lower developmental success in terms of egg-to-adult viability on both medium types, suggesting a possible trade-off between the traits investigated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980292"}
{"pmid": "20980293", "title": "Unexpected resilience of species with temperature-dependent sex determination at the Cretaceous-Palaeogene boundary.", "content": "Unexpected resilience of species with temperature-dependent sex determination at the Cretaceous-Palaeogene boundary. It has been suggested that climate change at the Cretaceous-Palaeogene (K-Pg) boundary, initiated by a bolide impact or volcanic eruptions, caused species with temperature-dependent sex determination (TSD), including dinosaurs, to go extinct because of a skewed sex ratio towards all males. To test this hypothesis, the sex-determining mechanisms (SDMs) of Cretaceous tetrapods of the Hell Creek Formation (Montana, USA) were inferred using parsimony optimizations of SDMs on a tree, including Hell Creek species and their extant relatives. Although the SDMs of non-avian dinosaurs could not be inferred, we were able to determine the SDMs of 62 species; 46 had genotypic sex determination (GSD) and 16 had TSD. The TSD hypothesis for extinctions performed poorly, predicting between 32 and 34 per cent of survivals and extinctions. Most surprisingly, of the 16 species with TSD, 14 of them survived into the Early Palaeocene. In contrast, 61 per cent of species with GSD went extinct. Possible explanations include minimal climate change at the K-Pg, or if climate change did occur, TSD species that survived had egg-laying behaviour that prevented the skewing of sex ratios, or had a sex ratio skewed towards female rather than male preponderance. Application of molecular clocks may allow the SDMs of non-avian dinosaurs to be inferred, which would be an important test of the pattern discovered here.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980293"}
{"pmid": "20980294", "title": "Performance of human groups in social foraging: the role of communication in consensus decision making.", "content": "Performance of human groups in social foraging: the role of communication in consensus decision making. Early hominids searched for dispersed food sources in a patchy, uncertain environment, and modern humans encounter equivalent spatial-temporal coordination problems on a daily basis. A fundamental, but untested assumption is that our evolved capacity for communication is integral to our success in such tasks, allowing information exchange and consensus decisions based on mutual consideration of pooled information. Here we examine whether communication enhances group performance in humans, and test the prediction that consensus decision-making underlies group success. We used bespoke radio-tagging methodology to monitor the incremental performance of communicating and non-communicating human groups (small group sizes of two to seven individuals), during a social foraging experiment. We found that communicating groups (n = 22) foraged more effectively than non-communicating groups (n = 21) and were able to reach consensus decisions (an 'agreement' on the most profitable foraging resource) significantly more often than non-communicating groups. Our data additionally suggest that gesticulations among group members played a vital role in the achievement of consensus decisions, and therefore highlight the importance of non-verbal signalling of intentions and desires for successful human cooperative behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980294"}
{"pmid": "20980295", "title": "Electrical signalling of dominance in a wild population of electric fish.", "content": "Electrical signalling of dominance in a wild population of electric fish. Animals often use signals to communicate their dominance status and avoid the costs of combat. We investigated whether the frequency of the electric organ discharge (EOD) of the weakly electric fish, Sternarchorhynchus sp., signals the dominance status of individuals. We correlated EOD frequency with body size and found a strong positive relationship. We then performed a competition experiment in which we found that higher frequency individuals were dominant over lower frequency ones. Finally, we conducted an electrical playback experiment and found that subjects more readily approached and attacked the stimulus electrodes when they played low-frequency signals than high-frequency ones. We propose that EOD frequency communicates dominance status in this gymnotiform species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980295"}
{"pmid": "20980296", "title": "Do I stand out or blend in? Conspicuousness awareness and consistent behavioural differences in hermit crabs.", "content": "Do I stand out or blend in? Conspicuousness awareness and consistent behavioural differences in hermit crabs. Animals titrate their behaviour against the level of risk and an individual's conspicuousness should influence decisions such as when to flee and for how long to hide. Conspicuousness will vary with variation in substrate colour. Since hermit crabs frequently change the shells they occupy, shell colour will also influence conspicuousness and to be aware of their conspicuousness would require information on both of these factors to be integrated. Reduced boldness in high-contrast shell and substrate combinations compared with situations of low contrast indicates that hermit crabs are aware of current conspicuousness. Differences between individuals remained consistent across conspicuousness levels indicating the presence of animal personalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980296"}
{"pmid": "20980297", "title": "Plant-ants feed their host plant, but above all a fungal symbiont to recycle nitrogen.", "content": "Plant-ants feed their host plant, but above all a fungal symbiont to recycle nitrogen. In ant-plant symbioses, plants provide symbiotic ants with food and specialized nesting cavities (called domatia). In many ant-plant symbioses, a fungal patch grows within each domatium. The symbiotic nature of the fungal association has been shown in the ant-plant Leonardoxa africana and its protective mutualist ant Petalomyrmex phylax. To decipher trophic fluxes among the three partners, food enriched in (13)C and (15)N was given to the ants and tracked in the different parts of the symbiosis up to 660 days later. The plant received a small, but significant, amount of nitrogen from the ants. However, the ants fed more intensively the fungus. The pattern of isotope enrichment in the system indicated an ant behaviour that functions specifically to feed the fungus. After 660 days, the introduced nitrogen was still present in the system and homogeneously distributed among ant, plant and fungal compartments, indicating efficient recycling within the symbiosis. Another experiment showed that the plant surface absorbed nutrients (in the form of simple molecules) whether or not it is coated by fungus. Our study provides arguments for a mutualistic status of the fungal associate and a framework for investigating the previously unsuspected complexity of food webs in ant-plant mutualisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980297"}
{"pmid": "20980298", "title": "Disturbance affects short-term facilitation, but not long-term saturation, of exotic plant invasion in New Zealand forest.", "content": "Disturbance affects short-term facilitation, but not long-term saturation, of exotic plant invasion in New Zealand forest. We investigate the spread of an exotic herb, Hieracium lepidulum, into a New Zealand Nothofagus forest with the aim of understanding how stand-development of tree populations, propagule pressure and invader persistence, affect invasion across the landscape and within communities. Using data repeatedly collected over 35 years, from 250 locations, we parametrize continuous-time Markov chain models and use these models to examine future projections of the invasion under a range of hypothetical scenarios. We found that the probability of invasion into a stand was relatively high following canopy disturbance and that local abundance of Hieracium was promoted by minor disturbances. However, model predictions extrapolated 45 years into the future show that neither the rate of landscape-level invasion, nor local population growth of Hieracium, was affected much by changing the frequency of canopy disturbance events. Instead, invasion levels were strongly affected by the ability of Hieracium to persist in the understorey following forest canopy closure, and by propagule supply from streams, forest edges and plants already established within the stand. Our results show that disturbance frequency has surprisingly little influence on the long-term trajectory of invasion, while invader persistence strongly determines invasion patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980298"}
{"pmid": "20980299", "title": "Geographical and temporal flexibility in the response to crosswinds by migrating raptors.", "content": "Geographical and temporal flexibility in the response to crosswinds by migrating raptors. Wind and ocean currents may potentially have important effects on travelling animals, as an animal which does not respond to lateral flow will be drifted from its intended direction of movement. By analysing daily movements of migrating ospreys Pandion haliaetus and marsh harriers Circus aeruginosus, as recorded by satellite telemetry, in relation to global wind data, we showed that these raptors allow on average 47 per cent drift. Furthermore, our analyses revealed significant geographical and temporal variation in the response to crosswinds. During some parts of the migration, the birds drifted and in other parts they compensated or even overcompensated. In some regions, the response of marsh harriers depended on the wind direction. They drifted when the wind came from one side and (over)compensated when the wind came from the opposite side, and this flexible response was different in different geographical regions. These results suggest that migrating raptors modulate their response to crosswinds at different places and times during their travels and show that individual birds use a much more varied repertoire of behavioural responses to wind than hitherto assumed. Our results may also explain why contrasting and variable results have been obtained in previous studies of the effect of wind on bird migration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980299"}
{"pmid": "20980300", "title": "Sizing up your enemy: individual predation vulnerability predicts migratory probability.", "content": "Sizing up your enemy: individual predation vulnerability predicts migratory probability. Partial migration, in which a fraction of a population migrate and the rest remain resident, occurs in an extensive range of species and can have powerful ecological consequences. The question of what drives differences in individual migratory tendency is a contentious one. It has been shown that the timing of partial migration is based upon a trade-off between seasonal fluctuations in predation risk and growth potential. Phenotypic variation in either individual predation risk or growth potential should thus mediate the strength of the trade-off and ultimately predict patterns of partial migration at the individual level (i.e. which individuals migrate and which remain resident). We provide cross-population empirical support for the importance of one component of this model--individual predation risk--in predicting partial migration in wild populations of bream Abramis brama, a freshwater fish. Smaller, high-risk individuals migrate with a higher probability than larger, low-risk individuals, and we suggest that predation risk maintains size-dependent partial migration in this system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980300"}
{"pmid": "20980301", "title": "Chimpanzees help conspecifics obtain food and non-food items.", "content": "Chimpanzees help conspecifics obtain food and non-food items. Chimpanzees (Pan troglodytes) sometimes help both humans and conspecifics in experimental situations in which immediate selfish benefits can be ruled out. However, in several experiments, chimpanzees have not provided food to a conspecific even when it would cost them nothing, leading to the hypothesis that prosociality in the food-provisioning context is a derived trait in humans. Here, we show that chimpanzees help conspecifics obtain both food and non-food items--given that the donor cannot get the food herself. Furthermore, we show that the key factor eliciting chimpanzees' targeted helping is the recipients' attempts to either get the food or get the attention of the potential donor. The current findings add to the accumulating body of evidence that humans and chimpanzees share the motivation and skills necessary to help others in situations in which they cannot selfishly benefit. Humans, however, show prosocial motives more readily and in a wider range of contexts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980301"}
{"pmid": "20980302", "title": "Heritability of female extra-pair paternity rate in song sparrows (Melospiza melodia).", "content": "Heritability of female extra-pair paternity rate in song sparrows (Melospiza melodia). The forces driving the evolution of extra-pair reproduction in socially monogamous animals remain widely debated and unresolved. One key hypothesis is that female extra-pair reproduction evolves through indirect genetic benefits, reflecting increased additive genetic value of extra-pair offspring. Such evolution requires that a female's propensity to produce offspring that are sired by an extra-pair male is heritable. However, additive genetic variance and heritability in female extra-pair paternity (EPP) rate have not been quantified, precluding accurate estimation of the force of indirect selection. Sixteen years of comprehensive paternity and pedigree data from socially monogamous but genetically polygynandrous song sparrows (Melospiza melodia) showed significant additive genetic variance and heritability in the proportion of a female's offspring that was sired by an extra-pair male, constituting major components of the genetic architecture required for extra-pair reproduction to evolve through indirect additive genetic benefits. However, estimated heritabilities were moderately small (0.12 and 0.18 on the observed and underlying latent scales, respectively). The force of selection on extra-pair reproduction through indirect additive genetic benefits may consequently be relatively weak. However, the additive genetic variance and non-zero heritability observed in female EPP rate allow for multiple further genetic mechanisms to drive and constrain mating system evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980302"}
{"pmid": "20980303", "title": "Neural processing of imminent collision in humans.", "content": "Neural processing of imminent collision in humans. Detecting a looming object and its imminent collision is imperative to survival. For most humans, it is a fundamental aspect of daily activities such as driving, road crossing and participating in sport, yet little is known about how the brain both detects and responds to such stimuli. Here we use functional magnetic resonance imaging to assess neural response to looming stimuli in comparison with receding stimuli and motion-controlled static stimuli. We demonstrate for the first time that, in the human, the superior colliculus and the pulvinar nucleus of the thalamus respond to looming in addition to cortical regions associated with motor preparation. We also implicate the anterior insula in making timing computations for collision events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980303"}
{"pmid": "20980304", "title": "Integrating species traits with extrinsic threats: closing the gap between predicting and preventing species declines.", "content": "Integrating species traits with extrinsic threats: closing the gap between predicting and preventing species declines. In studies of extinction risk, it is often insufficient to conclude that species with narrow ranges or small clutch sizes require prioritized protection. To improve conservation outcomes, we also need to know which threats interact with these traits to endanger some species but not others. In this study, we integrated the spatial patterns of key threats to Australian amphibians with species' ecological/life-history traits to both predict declining species and identify their likely threats. In addition to confirming the importance of previously identified traits (e.g. narrow range size), we find that extrinsic threats (primarily the disease chytridiomycosis and invasive mosquitofish) are equally important and interact with intrinsic traits (primarily ecological group) to create guild-specific pathways to decline in our model system. Integrating the spatial patterns of extrinsic threats in extinction risk analyses will improve our ability to detect and manage endangered species in the future, particularly where data deficiency is a problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980304"}
{"pmid": "20980305", "title": "Assassin bug uses aggressive mimicry to lure spider prey.", "content": "Assassin bug uses aggressive mimicry to lure spider prey. Assassin bugs (Stenolemus bituberus) hunt web-building spiders by invading the web and plucking the silk to generate vibrations that lure the resident spider into striking range. To test whether vibrations generated by bugs aggressively mimic the vibrations generated by insect prey, we compared the responses of spiders to bugs with how they responded to prey, courting male spiders and leaves falling into the web. We also analysed the associated vibrations. Similar spider orientation and approach behaviours were observed in response to vibrations from bugs and prey, whereas different behaviours were observed in response to vibrations from male spiders and leaves. Peak frequency and duration of vibrations generated by bugs were similar to those generated by prey and courting males. Further, vibrations from bugs had a temporal structure and amplitude that were similar to vibrations generated by leg and body movements of prey and distinctly different to vibrations from courting males or leaves, or prey beating their wings. To be an effective predator, bugs do not need to mimic the full range of prey vibrations. Instead bugs are general mimics of a subset of prey vibrations that fall within the range of vibrations classified by spiders as 'prey'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980305"}
{"pmid": "20980306", "title": "From phenotype to genotype: a Bayesian solution.", "content": "From phenotype to genotype: a Bayesian solution. The study of biological systems commonly depends on inferring the state of a 'hidden' variable, such as an underlying genotype, from that of an 'observed' variable, such as an expressed phenotype. However, this cannot be achieved using traditional quantitative methods when more than one genetic mechanism exists for a single observable phenotype. Using a novel latent class Bayesian model, it is possible to infer the prevalence of different genetic elements in a population given a sample of phenotypes. As an exemplar, data comprising phenotypic resistance to six antimicrobials obtained from passive surveillance of Salmonella Typhimurium DT104 are analysed to infer the prevalence of individual resistance genes, as well as the prevalence of a genomic island known as SGI1 and its variants. Three competing models are fitted to the data and distinguished between using posterior predictive p-values to assess their ability to predict the observed number of unique phenotypes. The results suggest that several SGI1 variants circulate in a few fixed forms through the population from which our data were derived. The methods presented could be applied to other types of phenotypic data, and represent a useful and generic mechanism of inferring the genetic population structure of organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980306"}
{"pmid": "20980307", "title": "Of lemmings and snowshoe hares: the ecology of northern Canada.", "content": "Of lemmings and snowshoe hares: the ecology of northern Canada. Two population oscillations dominate terrestrial community dynamics in northern Canada. In the boreal forest, the snowshoe hare (Lepus americanus) fluctuates in cycles with an 8-10 year periodicity and in tundra regions lemmings typically fluctuate in cycles with a 3-4 year periodicity. I review 60 years of research that has uncovered many of the causes of these population cycles, outline areas of controversy that remain and suggest key questions to address. Lemmings are keystone herbivores in tundra ecosystems because they are a key food resource for many avian and mammalian predators and are a major consumer of plant production. There remains much controversy over the role of predation, food shortage and social interactions in causing lemming cycles. Predation is well documented as a significant mortality factor limiting numbers. Food shortage is less likely to be a major limiting factor on population growth in lemmings. Social interactions might play a critical role in reducing the rate of population growth as lemming density rises. Snowshoe hares across the boreal forest are a key food for many predators and their cycles have been the subject of large-scale field experiments that have pinpointed predation as the key limiting factor causing these fluctuations. Predators kill hares directly and indirectly stress them by unsuccessful pursuits. Stress reduces the reproductive rate of female hares and is transmitted to their offspring who also suffer reduced reproductive rates. The maternal effects produced by predation risk induce a time lag in the response of hare reproductive rate to density, aiding the cyclic dynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980307"}
{"pmid": "20980308", "title": "Biological diversity in a changing world.", "content": "Biological diversity in a changing world. From the pioneering explorations of Joseph Banks (later a President of the Royal Society), to the present day, a great deal has been learnt about the extent, distribution and stability of biological diversity in the world. We now know that diverse life can be found even in the most inhospitable places. We have also learned that biological diversity changes through time over both large and small temporal scales. These natural changes track environmental conditions, and reflect ecological and evolutionary processes. However, anthropogenic activities, including overexploitation, habitat loss and climate change, are currently causing profound transformations in ecosystems and unprecedented loss of biological diversity. This series of papers considers temporal variation in biological diversity, examines the extent of human-related change relative to underlying natural change and builds on these insights to develop tools and policies to help guide us towards a sustainable future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980308"}
{"pmid": "20980309", "title": "Phylogenetic diversity measures based on Hill numbers.", "content": "Phylogenetic diversity measures based on Hill numbers. We propose a parametric class of phylogenetic diversity (PD) measures that are sensitive to both species abundance and species taxonomic or phylogenetic distances. This work extends the conventional parametric species-neutral approach (based on 'effective number of species' or Hill numbers) to take into account species relatedness, and also generalizes the traditional phylogenetic approach (based on 'total phylogenetic length') to incorporate species abundances. The proposed measure quantifies 'the mean effective number of species' over any time interval of interest, or the 'effective number of maximally distinct lineages' over that time interval. The product of the measure and the interval length quantifies the 'branch diversity' of the phylogenetic tree during that interval. The new measures generalize and unify many existing measures and lead to a natural definition of taxonomic diversity as a special case. The replication principle (or doubling property), an important requirement for species-neutral diversity, is generalized to PD. The widely used Rao's quadratic entropy and the phylogenetic entropy do not satisfy this essential property, but a simple transformation converts each to our measures, which do satisfy the property. The proposed approach is applied to forest data for interpreting the effects of thinning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980309"}
{"pmid": "20980310", "title": "Temporal turnover and the maintenance of diversity in ecological assemblages.", "content": "Temporal turnover and the maintenance of diversity in ecological assemblages. Temporal variation in species abundances occurs in all ecological communities. Here, we explore the role that this temporal turnover plays in maintaining assemblage diversity. We investigate a three-decade time series of estuarine fishes and show that the abundances of the individual species fluctuate asynchronously around their mean levels. We then use a time-series modelling approach to examine the consequences of different patterns of turnover, by asking how the correlation between the abundance of a species in a given year and its abundance in the previous year influences the structure of the overall assemblage. Classical diversity measures that ignore species identities reveal that the observed assemblage structure will persist under all but the most extreme conditions. However, metrics that track species identities indicate a narrower set of turnover scenarios under which the predicted assemblage resembles the natural one. Our study suggests that species diversity metrics are insensitive to change and that measures that track species ranks may provide better early warning that an assemblage is being perturbed. It also highlights the need to incorporate temporal turnover in investigations of assemblage structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980310"}
{"pmid": "20980311", "title": "Detecting temporal trends in species assemblages with bootstrapping procedures and hierarchical models.", "content": "Detecting temporal trends in species assemblages with bootstrapping procedures and hierarchical models. Quantifying patterns of temporal trends in species assemblages is an important analytical challenge in community ecology. We describe methods of analysis that can be applied to a matrix of counts of individuals that is organized by species (rows) and time-ordered sampling periods (columns). We first developed a bootstrapping procedure to test the null hypothesis of random sampling from a stationary species abundance distribution with temporally varying sampling probabilities. This procedure can be modified to account for undetected species. We next developed a hierarchical model to estimate species-specific trends in abundance while accounting for species-specific probabilities of detection. We analysed two long-term datasets on stream fishes and grassland insects to demonstrate these methods. For both assemblages, the bootstrap test indicated that temporal trends in abundance were more heterogeneous than expected under the null model. We used the hierarchical model to estimate trends in abundance and identified sets of species in each assemblage that were steadily increasing, decreasing or remaining constant in abundance over more than a decade of standardized annual surveys. Our methods of analysis are broadly applicable to other ecological datasets, and they represent an advance over most existing procedures, which do not incorporate effects of incomplete sampling and imperfect detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980311"}
{"pmid": "20980312", "title": "Integrating spatial and temporal approaches to understanding species richness.", "content": "Integrating spatial and temporal approaches to understanding species richness. Understanding species richness patterns represents one of the most fundamental problems in ecology. Most research in this area has focused on spatial gradients of species richness, with a smaller area of emphasis dedicated to understanding the temporal dynamics of richness. However, few attempts have been made to understand the linkages between the spatial and temporal patterns related to richness. Here, we argue that spatial and temporal richness patterns and the processes that drive them are inherently linked, and that our understanding of richness will be substantially improved by considering them simultaneously. The species-time-area relationship provides a case in point: successful description of the empirical spatio-temporal pattern led to a rapid development and testing of new theories. Other areas of research on species richness could also benefit from an explicitly spatio-temporal approach, and we suggest future directions for understanding the processes common to these two traditionally isolated fields of research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980312"}
{"pmid": "20980313", "title": "Biodiversity and biogeography of the atmosphere.", "content": "Biodiversity and biogeography of the atmosphere. The variation of life has predominantly been studied on land and in water, but this focus is changing. There is a resurging interest in the distribution of life in the atmosphere and the processes that underlie patterns in this distribution. Here, we review our current state of knowledge about the biodiversity and biogeography of the atmosphere, with an emphasis on micro-organisms, the numerically dominant forms of aerial life. We present evidence to suggest that the atmosphere is a habitat for micro-organisms, and not purely a conduit for terrestrial and aquatic life. Building on a rich history of research in terrestrial and aquatic systems, we explore biodiversity patterns that are likely to play an important role in the emerging field of air biogeography. We discuss the possibility of a more unified understanding of the biosphere, one that links knowledge about biodiversity and biogeography in the lithosphere, hydrosphere and atmosphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980313"}
{"pmid": "20980314", "title": "Evolutionary dynamics at high latitudes: speciation and extinction in polar marine faunas.", "content": "Evolutionary dynamics at high latitudes: speciation and extinction in polar marine faunas. Ecologists have long been fascinated by the flora and fauna of extreme environments. Physiological studies have revealed the extent to which lifestyle is constrained by low temperature but there is as yet no consensus on why the diversity of polar assemblages is so much lower than many tropical assemblages. The evolution of marine faunas at high latitudes has been influenced strongly by oceanic cooling during the Cenozoic and the associated onset of continental glaciations. Glaciation eradicated many shallow-water habitats, especially in the Southern Hemisphere, and the cooling has led to widespread extinction in some groups. While environmental conditions at glacial maxima would have been very different from those existing today, fossil evidence indicates that some lineages extend back well into the Cenozoic. Oscillations of the ice-sheet on Milankovitch frequencies will have periodically eradicated and exposed continental shelf habitat, and a full understanding of evolutionary dynamics at high latitude requires better knowledge of the links between the faunas of the shelf, slope and deep-sea. Molecular techniques to produce phylogenies, coupled with further palaeontological work to root these phylogenies in time, will be essential to further progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980314"}
{"pmid": "20980315", "title": "The origins of modern biodiversity on land.", "content": "The origins of modern biodiversity on land. Comparative studies of large phylogenies of living and extinct groups have shown that most biodiversity arises from a small number of highly species-rich clades. To understand biodiversity, it is important to examine the history of these clades on geological time scales. This is part of a distinct 'phylogenetic expansion' view of macroevolution, and contrasts with the alternative, non-phylogenetic 'equilibrium' approach to the history of biodiversity. The latter viewpoint focuses on density-dependent models in which all life is described by a single global-scale model, and a case is made here that this approach may be less successful at representing the shape of the evolution of life than the phylogenetic expansion approach. The terrestrial fossil record is patchy, but is adequate for coarse-scale studies of groups such as vertebrates that possess fossilizable hard parts. New methods in phylogenetic analysis, morphometrics and the study of exceptional biotas allow new approaches. Models for diversity regulation through time range from the entirely biotic to the entirely physical, with many intermediates. Tetrapod diversity has risen as a result of the expansion of ecospace, rather than niche subdivision or regional-scale endemicity resulting from continental break-up. Tetrapod communities on land have been remarkably stable and have changed only when there was a revolution in floras (such as the demise of the Carboniferous coal forests, or the Cretaceous radiation of angiosperms) or following particularly severe mass extinction events, such as that at the end of the Permian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980315"}
{"pmid": "20980316", "title": "Ecological correlates of range shifts of Late Pleistocene mammals.", "content": "Ecological correlates of range shifts of Late Pleistocene mammals. Understanding and predicting how species' distributions will shift as climate changes are central questions in ecology today. The late Quaternary of North America represents a natural experiment in which we can evaluate how species responded during the expansion and contraction of the glaciers. Here, we ask whether species' range shifts differ because of taxonomic affinity, life-history traits, body size or topographic heterogeneity and whether the species survived the megafaunal extinction. There was no difference in range shifts between victims and survivors of the megafaunal extinction. In general, the change in the size of a species' range is not well correlated with any of the ecological or life-history traits evaluated. However, there are significant relationships between some variables and the movements of the centroids of ranges. Differences in the distances shifted exist among orders, although this is probably a result of body size differences as larger bodied species show larger shifts. Although there are a few exceptions, the distance that species shifted their range was weakly correlated with life-history traits. Finally, species in more topographically heterogeneous areas show smaller shifts than species in less-diverse areas. Overall, these results indicate that when trying to predict species range shifts in the future, body size, lifespan and the topographic relief of the landscape should be taken into account.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980316"}
{"pmid": "20980317", "title": "A stochastic, evolutionary model for range shifts and richness on tropical elevational gradients under Quaternary glacial cycles.", "content": "A stochastic, evolutionary model for range shifts and richness on tropical elevational gradients under Quaternary glacial cycles. Quaternary glacial-interglacial cycles repeatedly forced thermal zones up and down the slopes of mountains, at all latitudes. Although no one doubts that these temperature cycles have left their signature on contemporary patterns of geography and phylogeny, the relative roles of ecology and evolution are not well understood, especially for the tropics. To explore key mechanisms and their interactions in the context of chance events, we constructed a geographical range-based, stochastic simulation model that incorporates speciation, anagenetic evolution, niche conservatism, range shifts and extinctions under late Quaternary temperature cycles along tropical elevational gradients. In the model, elevational patterns of species richness arise from the differential survival of founder lineages, consolidated by speciation and the inheritance of thermal niche characteristics. The model yields a surprisingly rich variety of realistic patterns of phylogeny and biogeography, including close matches to a variety of contemporary elevational richness profiles from an elevational transect in Costa Rica. Mountaintop extinctions during interglacials and lowland extinctions at glacial maxima favour mid-elevation lineages, especially under the constraints of niche conservatism. Asymmetry in temperature (greater duration of glacial than of interglacial episodes) and in lateral area (greater land area at low than at high elevations) have opposing effects on lowland extinctions and the elevational pattern of species richness in the model--and perhaps in nature, as well.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980317"}
{"pmid": "20980318", "title": "Anthropogenic impacts on tropical forest biodiversity: a network structure and ecosystem functioning perspective.", "content": "Anthropogenic impacts on tropical forest biodiversity: a network structure and ecosystem functioning perspective. Huge areas of diverse tropical forest are lost or degraded every year with dramatic consequences for biodiversity. Deforestation and fragmentation, over-exploitation, invasive species and climate change are the main drivers of tropical forest biodiversity loss. Most studies investigating these threats have focused on changes in species richness or species diversity. However, if we are to understand the absolute and long-term effects of anthropogenic impacts on tropical forests, we should also consider the interactions between species, how those species are organized in networks, and the function that those species perform. I discuss our current knowledge of network structure and ecosystem functioning, highlighting empirical examples of their response to anthropogenic impacts. I consider the future prospects for tropical forest biodiversity, focusing on biodiversity and ecosystem functioning in secondary forest. Finally, I propose directions for future research to help us better understand the effects of anthropogenic impacts on tropical forest biodiversity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980318"}
{"pmid": "20980319", "title": "Disturbance and change in biodiversity.", "content": "Disturbance and change in biodiversity. Understanding how disturbance affects biodiversity is important for both fundamental and applied reasons. Here, I investigate how disturbances with different ecological effects change biodiversity metrics. I define three main types of disturbance effects: D disturbance (shifts in mortality rate), B disturbance (shifts in reproductive rates) and K disturbance (shifts in carrying capacity). Numerous composite disturbances can be defined including any combination of these three types of ecological effects. The consequences of D, B and K disturbances, as well as of composite DBK disturbances are examined by comparing metrics before and after a disturbance, in disturbed and undisturbed communities. I use simulations of neutral communities and examine species richness, total abundance and species abundance distributions. The patterns of change in biodiversity metrics are consistent among different types of disturbance. K disturbance has the most severe effects, followed by D disturbance, and B disturbance has nearly negligible effects. Consequences of composite DBK disturbances are more complex than any of the three types of disturbance, with unimodal relationships along a disturbance gradient arising when D, B and K are negatively correlated. Importantly, regardless of disturbance type, community isolation enhances the negative consequences and hinders the positive effects of disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980319"}
{"pmid": "20980320", "title": "Temporal biodiversity change in transformed landscapes: a southern African perspective.", "content": "Temporal biodiversity change in transformed landscapes: a southern African perspective. Landscape transformation by humans is virtually ubiquitous, with several suggestions being made that the world's biomes should now be classified according to the extent and nature of this transformation. Even those areas that are thought to have a relatively limited human footprint have experienced substantial biodiversity change. This is true of both marine and terrestrial systems of southern Africa, a region of high biodiversity and including several large conservation areas. Global change drivers have had substantial effects across many levels of the biological hierarchy as is demonstrated in this review, which focuses on terrestrial systems. Interactions among drivers, such as between climate change and invasion, and between changing fire regimes and invasion, are complicating attribution of change effects and management thereof. Likewise CO(2) fertilization is having a much larger impact on terrestrial systems than perhaps commonly acknowledged. Temporal changes in biodiversity, and the seeming failure of institutional attempts to address them, underline a growing polarization of world views, which is hampering efforts to address urgent conservation needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980320"}
{"pmid": "20980321", "title": "Population and geographic range dynamics: implications for conservation planning.", "content": "Population and geographic range dynamics: implications for conservation planning. Continuing downward trends in the population sizes of many species, in the conservation status of threatened species, and in the quality, extent and connectedness of habitats are of increasing concern. Identifying the attributes of declining populations will help predict how biodiversity will be impacted and guide conservation actions. However, the drivers of biodiversity declines have changed over time and average trends in abundance or distributional change hide significant variation among species. While some populations are declining rapidly, the majority remain relatively stable and others are increasing. Here we dissect out some of the changing drivers of population and geographic range change, and identify biological and geographical correlates of winners and losers in two large datasets covering local population sizes of vertebrates since 1970 and the distributions of Galliform birds over the last two centuries. We find weak evidence for ecological and biological traits being predictors of local decline in range or abundance, but stronger evidence for the role of local anthropogenic threats and environmental change. An improved understanding of the dynamics of threat processes and how they may affect different species will help to guide better conservation planning in a continuously changing world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980321"}
{"pmid": "20980322", "title": "Transitional states in marine fisheries: adapting to predicted global change.", "content": "Transitional states in marine fisheries: adapting to predicted global change. Global climate change has the potential to substantially alter the production and community structure of marine fisheries and modify the ongoing impacts of fishing. Fish community composition is already changing in some tropical, temperate and polar ecosystems, where local combinations of warming trends and higher environmental variation anticipate the changes likely to occur more widely over coming decades. Using case studies from the Western Indian Ocean, the North Sea and the Bering Sea, we contextualize the direct and indirect effects of climate change on production and biodiversity and, in turn, on the social and economic aspects of marine fisheries. Climate warming is expected to lead to (i) yield and species losses in tropical reef fisheries, driven primarily by habitat loss; (ii) community turnover in temperate fisheries, owing to the arrival and increasing dominance of warm-water species as well as the reduced dominance and departure of cold-water species; and (iii) increased diversity and yield in Arctic fisheries, arising from invasions of southern species and increased primary production resulting from ice-free summer conditions. How societies deal with such changes will depend largely on their capacity to adapt--to plan and implement effective responses to change--a process heavily influenced by social, economic, political and cultural conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980322"}
{"pmid": "20980324", "title": "Characterization of the interactions between architecture and source-sink relationships in winter oilseed rape (Brassica napus) using the GreenLab model.", "content": "Characterization of the interactions between architecture and source-sink relationships in winter oilseed rape (Brassica napus) using the GreenLab model. This study aimed to characterize the interaction between architecture and source-sink relationships in winter oilseed rape (WOSR): do the costs of ramification compromise the source-sink ratio during seed filling? The GreenLab model is a good candidate to address this question because it has been already used to describe interactions between source-sink relationships and architecture for other species. However, its adaptation to WOSR is a challenge because of the complexity of its developmental scheme, especially during the reproductive phase. Equations were added in GreenLab to compute expansion delays for ramification, flowering of each axis and photosynthesis of pods including the energetic cost of oil synthesis. Experimental field data were used to estimate morphological parameters while source-sink parameters of the model were estimated by adjustment of model outputs to the data. Ecophysiological outputs were used to assess the sources/sink relationships during the whole growth cycle. First results indicated that, at the plant scale, the model correctly simulates the dynamics of organ growth. However, at the organ scale, errors were observed that could be explained either by secondary growth that was not incorporated or by uncertainties in morphological parameters (durations of expansion and life). Ecophysiological outputs highlighted the dramatic negative impact of ramification on the source-sink ratio, as well as the decrease in this ratio during seed filling despite pod envelope photosynthesis that allowed significant biomass production to be maintained. This work is a promising first step in the construction of a structure-function model for a plant as complex as WOSR. Once tested for other environments and/or genotypes, the model can be used for studies on WOSR architectural plasticity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980324"}
{"pmid": "20980323", "title": "The future of the oceans past.", "content": "The future of the oceans past. Major macroevolutionary events in the history of the oceans are linked to changes in oceanographic conditions and environments on regional to global scales. Even small changes in climate and productivity, such as those that occurred after the rise of the Isthmus of Panama, caused major changes in Caribbean coastal ecosystems and mass extinctions of major taxa. In contrast, massive influxes of carbon at the end of the Palaeocene caused intense global warming, ocean acidification, mass extinction throughout the deep sea and the worldwide disappearance of coral reefs. Today, overfishing, pollution and increases in greenhouse gases are causing comparably great changes to ocean environments and ecosystems. Some of these changes are potentially reversible on very short time scales, but warming and ocean acidification will intensify before they decline even with immediate reduction in emissions. There is an urgent need for immediate and decisive conservation action. Otherwise, another great mass extinction affecting all ocean ecosystems and comparable to the upheavals of the geological past appears inevitable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980323"}
{"pmid": "20980325", "title": "Sexual dimorphism in resource acquisition and deployment: both size and timing matter.", "content": "Sexual dimorphism in resource acquisition and deployment: both size and timing matter. The males and females of many dioecious plant species differ from one another in important life-history traits, such as their size. If male and female reproductive functions draw on different resources, for example, one should expect males and females to display different allocation strategies as they grow. Importantly, these strategies may differ not only between the two sexes, but also between plants of different age and therefore size. Results are presented from an experiment that asks whether males and females of Mercurialis annua, an annual plant with indeterminate growth, differ over time in their allocation of two potentially limiting resources (carbon and nitrogen) to vegetative (below- and above-ground) and reproductive tissues. Comparisons were made of the temporal patterns of biomass allocation to shoots, roots and reproduction and the nitrogen content in the leaves between the sexes of M. annua by harvesting plants of each sex after growth over different periods of time. Males and females differed in their temporal patterns of allocation. Males allocated more to reproduction than females at early stages, but this trend was reversed at later stages. Importantly, males allocated proportionally more of their biomass towards roots at later stages, but the roots of females were larger in absolute terms. The study points to the important role played by both the timing of resource deployment and the relative versus absolute sizes of the sinks and sources in sexual dimorphism of an annual plant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980325"}
{"pmid": "20980326", "title": "The effect of breathing manner on inferior vena caval diameter.", "content": "The effect of breathing manner on inferior vena caval diameter. Although the inspiratory 'collapse' of the inferior vena cava (IVC) has been used to signify normal central venous pressure, the effect of the manner of breathing IVC size is incompletely understood. As intra-abdominal pressure rises during descent of the diaphragm, we hypothesized that inspiration through diaphragmatic excursion may have a compressive effect on the IVC. We measured minimal and maximal intrahepatic IVC diameter on echocardiography and popliteal venous return by spectral Doppler during isovolemic inspiratory efforts in 19 healthy non-obese volunteers who were instructed to inhale using either diaphragmatic or chest wall expansion. During inspiration, the maximal diaphragmatic excursion and popliteal vein flow were compared between breathing methods. The IVC 'collapsibility index,' IVCCI, was calculated as (IVC(max)-IVC(min))/IVC(max). The difference in diaphragmatic excursion between diaphragmatic and chest wall breaths in each subject was correlated with the corresponding change in IVCCI. Diaphragmatic breathing resulted in more diaphragmatic excursion than chest wall breathing (median 3.4 cm, range 1.7-5.8 vs. 2.2 cm, range 1.0-5.2, P= 0.0003), and was universally associated with decreased popliteal venous return (19/19 vs. 9/19 subjects, P< 0.004). The difference in diaphragmatic excursion correlated with the difference in IVCCI (Spearman's rho = 0.53, P= 0.024). During inspiration of equivalent tidal volumes, the reduction in IVC diameter and lower extremity venous return was related to diaphragmatic excursion, suggesting that the IVC may be compressed through descent of the diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980326"}
{"pmid": "20980327", "title": "Usefulness of transthoracic Doppler echocardiography for noninvasive assessment of coronary blood flow in a patient with symptomatic myocardial bridging.", "content": "Usefulness of transthoracic Doppler echocardiography for noninvasive assessment of coronary blood flow in a patient with symptomatic myocardial bridging. Myocardial bridging (MB) is a congenital anomaly characterized by systolic compression of the tunnelled arterial segment. MB may cause myocardial ischaemia due to abnormal coronary blood flow. We report a case of MB in which transthoracic Doppler echocardiography was used to evaluate the long-term effect of beta-blocker therapy on abnormal coronary blood flow. In this case, beta-blocker therapy with bisoprolol (5.0 mg/day) for 1 month eliminated the patient's symptoms and normalized coronary blood flow through the tunnelled arterial segment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980327"}
{"pmid": "20980328", "title": "Blood pressure targets of antihypertensive treatment: up and down the J-shaped curve.", "content": "Blood pressure targets of antihypertensive treatment: up and down the J-shaped curve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980328"}
{"pmid": "20980331", "title": "How reproductive and regenerative medicine meet in a Chinese fertility clinic. Interviews with women about the donation of embryos to stem cell research.", "content": "How reproductive and regenerative medicine meet in a Chinese fertility clinic. Interviews with women about the donation of embryos to stem cell research. The social interface between reproductive medicine and embryonic stem cell research has been investigated in a pilot study at a large IVF clinic in central China. Methods included observation, interviews with hospital personnel, and five in-depth qualitative interviews with women who underwent IVF and who were asked for their consent to the donation of embryos for use in medical (in fact human embryonic stem cell) research. This paper reports, and discusses from an ethical perspective, the results of an analysis of these interviews. The participants talked of extreme social pressure to become pregnant. Once they had a baby, 'spare' embryos lost practical significance due to the Chinese one-child policy. In the context of decision making about donating embryos to research, the women used the clinical distinctions between 'good and bad quality' embryos and also between frozen and transferred embryos, as guiding moral distinctions. In the absence of concrete information about what sort of research their embryos should be used for, the women interviewed either refused consent (for fear that the embryo would be given to another couple) or accepted, expressing motives of solidarity with other women in a similar situation. This reveals that they filled the knowledge gap with an image of research improving fertility treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980331"}
{"pmid": "20980330", "title": "A controlled evaluation of the WHO Safe Communities model approach to injury prevention: increasing child restraint use in motor vehicles.", "content": "A controlled evaluation of the WHO Safe Communities model approach to injury prevention: increasing child restraint use in motor vehicles. To measure the effect of the WHO Safe Communities model approach to increasing child restraint use in motor vehicles. Pre- and post-intervention observations of restraint use in motor vehicles in several sites in the target area, and in a comparison area community. Community; southeast Dallas, Texas, 2003-2005. A multifaceted approach to increasing use of child safety seats, booster seats and seat belts that included efforts in schools, day care centres, neighbourhoods and a local public clinic, along with child safety seat classes and a low-cost distribution programme. Prevalence of restraint use among children 0-8 years old riding in motor vehicles. In the target area, the adjusted child restraint use increased by 23.9 percentage points versus 11.8 in the comparison area (difference 12.1; 95% CI 9.9 to 14.3), and adjusted driver seat belt use increased by 16.3 percentage points in the target area versus 4.9 in the comparison area (difference 11.4; 95% CI 11.0 to 11.7). Multivariable multilevel analysis showed that the increase in the target area was significantly greater than in the comparison area for child restraint use (OR 1.6; 95% CI 1.2 to 2.2), as well as for driver seat belt use and proportion of children riding in the back seat. The Safe Communities approach was successful in promoting the use of child restraints in motor vehicles through a multifaceted intervention that included efforts in various community settings, instructional classes and child safety seat distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980330"}
{"pmid": "20980332", "title": "Persistent left with absent right superior vena cava.", "content": "Persistent left with absent right superior vena cava.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980332"}
{"pmid": "20980333", "title": "Coffee consumption and the risk of heart failure in Finnish men and women.", "content": "Coffee consumption and the risk of heart failure in Finnish men and women. To evaluate the association of coffee consumption with the risk of heart failure (HF) in the Finnish population. Prospective population-based cohort study. This study, which is a part of FINRISK study, was carried out in Finland. Study cohorts included 59,490 Finnish participants aged 25-74 years who were free of HF at baseline. HF (2020 men and 1807 women) during a mean follow-up of 19.2 years. Multivariable-adjusted (age, study year, body mass index, smoking, education, alcohol consumption, tea consumption, physical activity, systolic blood pressure, history of myocardial infarction, history of valvular heart disease, history of diabetes and total cholesterol) HRs (with 95% CI) of HF associated with the amount of coffee consumption daily (0, 1-2, 3-4, 5-6, 7-9 and ≥10 cups) were 1.00, 0.91 (0.71 to 1.16), 0.88 (0.70 to 1.10), 0.91 (0.73 to 1.13), 0.96 (0.76 to 1.22) and 1.02 (0.80 to 1.30) (p(trend) = 0.485) for men and 1.00, 0.73 (0.56 to 0.97), 0.77 (0.60 to 0.98), 0.68 (0.53 to 0.88), 0.80 (0.61 to 1.04) and 0.88 (0.65 to 1.19) (p(trend) = 0.007) for women, respectively. Stratification by age, smoking status, alcohol consumption, history of type 2 diabetes mellitus and body mass index gave similar results. Coffee consumption does not increase the risk of HF in Finnish men and women. In women, an inverse association was observed between low to moderate coffee consumption and the risk of HF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980333"}
{"pmid": "20980334", "title": "Successful treatment of aortic bio-prosthetic valve failure by transcatheter aortic valve implantation.", "content": "Successful treatment of aortic bio-prosthetic valve failure by transcatheter aortic valve implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980334"}
{"pmid": "20980336", "title": "Engineering the stability and the activity of a glycoside hydrolase.", "content": "Engineering the stability and the activity of a glycoside hydrolase. Glycosidases, the enzymes responsible in nature for the catabolism of carbohydrates, are well-studied catalysts widely used in industrial biotransformations and oligosaccharide synthesis, which are also attractive targets for drug development. Glycosidases from hyperthermophilic organisms (thriving at temperatures > 85 °C) are also interesting models to understand the molecular basis of protein stability and to produce robust tools for industrial applications. Here, we review the results obtained in the last two decades by our group on a β-glycosidase from the hyperthermophilic Archaeon Sulfolobus solfataricus. Our findings will be presented in the general context of the stability of proteins from hyperthermophiles and of the chemo-enzymatic synthesis of oligosaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980336"}
{"pmid": "20980337", "title": "Involvement of MyoD and PEA3 in regulation of transcription activity of MDR1 gene.", "content": "Involvement of MyoD and PEA3 in regulation of transcription activity of MDR1 gene. Overexpression of multidrug resistance 1 (MDR1) in cancer remains one of the major causes for the failure of chemotherapy. In the present study, we found that MyoD and PEA3 could activate P-glycoprotein (P-gp) expression in SGC7901 cells. Knockdown of MyoD and PEA3 attenuated MDR1 expression and increased the sensitivity of multidrug resistant cancer cells to cytotoxic drugs that were transported by P-gp in SGC7901/VCR cells. MyoD or PEA3 could bind to the E-box and PEA3 sites on the MDR1 promoter and activate its transcription. The regulation of MDR1 expression by MyoD and PEA3 may provide potential ways to overcome MDR in cancer treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980337"}
{"pmid": "20980335", "title": "Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study.", "content": "Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study. This randomized, open-label, active-controlled, dose-finding phase IIb study evaluated the efficacy and safety of trabedersen (AP 12009) administered intratumorally by convection-enhanced delivery compared with standard chemotherapy in patients with recurrent/refractory high-grade glioma. One hundred and forty-five patients with central reference histopathology of recurrent/refractory glioblastoma multiforme (GBM) or anaplastic astrocytoma (AA) were randomly assigned to receive trabedersen at doses of 10 or 80 µM or standard chemotherapy (temozolomide or procarbazine/lomustine/vincristine). Primary endpoint was 6-month tumor control rate, and secondary endpoints included response at further timepoints, survival, and safety. Six-month tumor control rates were not significantly different in the entire study population (AA and GBM). Prespecified AA subgroup analysis showed a significant benefit regarding the 14-month tumor control rate for 10 µM trabedersen vs chemotherapy (p= .0032). The 2-year survival rate had a trend for superiority for 10 µM trabedersen vs chemotherapy (p = .10). Median survival for 10 µM trabedersen was 39.1 months compared with 35.2 months for 80 µM trabedersen and 21.7 months for chemotherapy (not significant). In GBM patients, response and survival results were comparable among the 3 arms. Exploratory analysis on GBM patients aged ≤55 years with Karnofsky performance status >80% at baseline indicated a 3-fold survival at 2 and 3 years for 10 µM trabedersen vs chemotherapy. The frequency of patients with related or possibly drug-related adverse events was higher with standard chemotherapy (64%) than with 80 µM trabedersen (43%) and 10 µM trabedersen (27%). Superior efficacy and safety for 10 µM trabedersen over 80 µM trabedersen and chemotherapy and positive risk-benefit assessment suggest it as the optimal dose for further clinical development in high-grade glioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980335"}
{"pmid": "20980338", "title": "What's there in a name: tropical calcific pancreatitis and idiopathic chronic pancreatitis in India.", "content": "What's there in a name: tropical calcific pancreatitis and idiopathic chronic pancreatitis in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980338"}
{"pmid": "20980340", "title": "Cost benefit of out of hours endoscopy: the options.", "content": "Cost benefit of out of hours endoscopy: the options.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980340"}
{"pmid": "20980339", "title": "Hepatitis B viraemia: its heritability and association with common genetic variation in the interferon gamma signalling pathway.", "content": "Hepatitis B viraemia: its heritability and association with common genetic variation in the interferon gamma signalling pathway. High viraemia of hepatitis B virus (HBV) influences all phases in the development of hepatocellular carcinoma (HCC). This study was designed to estimate the overall contribution of host genetics to HBV viraemia, and investigate the influence of common single-nucleotide polymorphisms (SNPs) in the interferon γ (IFNγ) signalling pathway, which is pivotal in the non-cytolytic clearance of HBV. We first determined familial correlations and heritability (ie, proportion of phenotypic variation that is attributable to additive genetic factors) for HBV viraemia using 280 HCC families, including 766 adult HBV carriers. Then family-based association analysis was conducted for viraemia with a panel of 40 SNPs across ten IFNγ-related genes. For replication, seven tagging SNPs in identified candidate regions were also tested in a further 1011 unrelated individuals with longitudinal data on HBV viraemia over 16 years. After adjustment for HBV genotype and sex, significant correlations for viraemia were detected among both siblings and mother-child pairs. Heritability accounted for approximately 30% (p<0.0002) of the variance of viral load, whereas HBV genotype and sex together explained less than 3%. Heritability estimates increased up to 74.0% after further exclusion of subjects with episodes of liver biochemical abnormalities. Our initial family-based association analysis identified two SNPs (rs2284553 (intronic SNP) and rs9808753 (Q64R)) on the IFNγ receptor 2 (IFNGR2) gene that were robustly associated with viraemia after multitest correction (all p<0.02). The SNPs were also associated with the longitudinal levels of viraemia and the persistence of a high viraemia of ≥4.39 log copies/ml (all p<0.0001) in unrelated individuals. HBV viraemia appears to have substantial heritability. Polymorphisms in the IFNGR2 gene appear to be associated with the variability of viraemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980339"}
{"pmid": "20980341", "title": "Acute, severe constipation in a 58-year-old Japanese patient.", "content": "Acute, severe constipation in a 58-year-old Japanese patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980341"}
{"pmid": "20980343", "title": "Idiopathic chronic pancreatitis in India.", "content": "Idiopathic chronic pancreatitis in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980343"}
{"pmid": "20980342", "title": "Confocal laser endomicroscopy is a new imaging modality for recognition of intramucosal bacteria in inflammatory bowel disease in vivo.", "content": "Confocal laser endomicroscopy is a new imaging modality for recognition of intramucosal bacteria in inflammatory bowel disease in vivo. Interaction of bacteria with the immune system within the intestinal mucosa plays a key role in the pathogenesis of inflammatory bowel disease (IBD). The aim of the current study was to develop a fluorescein-aided confocal laser endomicroscopy (CLE) method to visualise intramucosal enteric bacteria in vivo and to determine the involved mucosal area in the colon and ileum in patients with ulcerative colitis (UC) and Crohn's disease (CD). Initially, E coli strains expressing enhanced green fluorescent protein (pEGFP) were endomicroscopically imaged in mice. In addition, ex vivo and in vivo imaging of fluorescent human enteric bacteria was performed to specify the distinct endomicroscopic appearance of enteral bacteria. Targeted mucosal biopsies towards endomicroscopic identifiable intramucosal bacteria and negative mucosal areas were prospectively obtained during colonoscopy and correlated with bench-top fluorescence microscopy (FISH) to prove the endomicroscopic visualisation of intramucosal bacteria. Finally, a retrospective analysis as well as a prospective study was performed in patients with UC and CD to confirm the presence and distribution of intramucosal bacteria within the gut. Confocal endomicroscopy was able to identify intramucosal pEGFP E coli in mice and strains of enteric microflora in the mucosa of humans. Using FISH as the gold standard, evaluation of 21 patients showed that CLE had a sensitivity of 89% and specificity of 100% to identify intramucosal bacteria. In a retrospective study, 113 patients with CD and UC had intramucosal bacteria significantly more often than 50 control patients (66% vs 60% vs 14%, p<0.001). This result was confirmed in a prospective study in which 10 patients with CD and 10 with UC had a significantly wider distribution of involvement with intramucosal bacteria in the colon and terminal ileum compared with 10 controls (85.2% vs 75.9% vs 16.8%, p<0.0001). CLE is a new tool that can image intramucosal bacteria in vivo in patients with IBD. Intramucosal bacteria are found more frequently and with a wider distribution in patients with IBD than in patients with a normal intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980342"}
{"pmid": "20980344", "title": "Asteroids in the blood.", "content": "Asteroids in the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980344"}
{"pmid": "20980345", "title": "The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon.", "content": "The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon. The non-steroidal anti-inflammatory drug sulindac is an effective chemopreventive agent in sporadic colorectal cancer but its potential benefit in mismatch repair deficient cancers remains to be defined. We wanted to determine whether genetic defects that are relevant for colorectal cancer, such as Msh2 or p53 deficiency, would influence the efficiency of sulindac chemoprevention or increase the side effects. Msh2 or p53 deficient and wild-type mice received feed containing 160-320 ppm sulindac for up to 25 weeks with or without a concurrent treatment with the carcinogen azoxymethane. Colon tissue was analysed by histopathology and molecular biology methods. We show that sulindac prevented azoxymethane-induced distal colon tumours in all mice. In the proximal colon, however, sulindac induced new inflammatory lesions on the mucosal folds, which further developed into adenocarcinoma in up to 18-25% of the p53 or Msh2 deficient mice but rarely in wild-type mice. This region in the proximal colon was characterised by a distinct profile of pro- and anti-inflammatory factors, which were modulated by the sulindac diet, including upregulation of hypoxia inducible factor 1α and macrophage inflammatory protein 2. These data show that the sulindac diet promotes carcinogenesis in the mouse proximal colon possibly through chronic inflammation. Sulindac has both beneficial and harmful effects in vivo, which are associated with different microenvironments within the colon of experimental mice. Deficiency for the Msh2 or p53 tumour suppressor genes increases the harmful side effects of long-term sulindac treatment in the mouse colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980345"}
{"pmid": "20980347", "title": "Re: Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol.", "content": "Re: Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980347"}
{"pmid": "20980346", "title": "An outbreak of norovirus infection linked to oyster consumption at a UK restaurant, February 2010.", "content": "An outbreak of norovirus infection linked to oyster consumption at a UK restaurant, February 2010. We present the investigation of an outbreak of gastroenteritis at a UK restaurant incorporating both epidemiological and microbiological analysis. Structured postal questionnaires were sent to 30 diners who ate at the restaurant during the outbreak period (5-7 February 2010). Stool specimens collected from staff and diners were submitted for bacterial culture and norovirus testing, and 15 Pacific oysters (Crassostrea gigas) from the batch served during the outbreak period were tested for norovirus. A strong association was observed between illness and oyster consumption (odds ratio undefined, confidence interval: 11.7 to infinity, P = 0.00001). Multiple different sequences of norovirus RNA were present in both stool and oyster specimens, typical of a shellfish origin. Several contemporaneous norovirus outbreaks throughout the UK were linked to oysters, particularly, though not exclusively, those sourced from Carlingford Lough in Ireland (as in this study), which were subsequently withdrawn from distribution. Despite the risk to human health, there is significant uncertainty surrounding the quantitative correlation between oyster norovirus levels and consumer illness. Continued research should help further our understanding of this crucial correlation and identify ways in which viral depuration of oysters can be enhanced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980346"}
{"pmid": "20980348", "title": "Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation.", "content": "Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation. Chronic inflammation is deeply involved in induction of aberrant DNA methylation, but it is unclear whether any type of persistent inflammation can induce methylation and how induction of cell proliferation is involved. In this study, Mongolian gerbils were treated with five kinds of inflammation inducers [Helicobacter pylori with cytotoxin-associated gene A (CagA), H.pylori without CagA, Helicobacter felis, 50% ethanol (EtOH) and saturated sodium chloride (NaCl) solution]. Two control groups were treated with a mutagenic carcinogen that induces little inflammation (20 p.p.m. of N-methyl-N-nitrosourea) and without any treatment. After 20 weeks, chronic inflammation with lymphocyte and macrophage infiltration was prominent in the three Helicobacter groups, whereas neutrophil infiltration was mainly observed in the EtOH and NaCl groups. Methylation levels of eight CpG islands significantly increased only in the three Helicobacter groups. By Ki-67 staining, cell proliferation was most strongly induced in the NaCl group, demonstrating that induction of cell proliferation is not sufficient for methylation induction. Among the inflammation-related genes, Il1b, Nos2 and Tnf showed increased expression specifically in the three Helicobacter groups. In human gastric mucosae infected by H.pylori, NOS2 and TNF were also increased. These data showed that inflammation due to infection of the three Helicobacter strains has a strong potential to induce methylation, regardless of their CagA statuses, and increased cell proliferation was not sufficient for methylation induction. It was suggested that specific types of inflammation characterized by expression of specific inflammation-related genes, along with increased cell proliferation, are necessary for methylation induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980348"}
{"pmid": "20980350", "title": "Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors.", "content": "Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors. A hallmark of cancer is aberrant DNA methylation, consisting of global hypomethylation and regional hypermethylation of tumor suppressor genes. DNA methyltransferase inhibitors have been recognized as promising candidate anticancer drugs. Drug development has focused on DNA methylation inhibitors with the goal of activating tumor suppressor genes silenced by DNA methylation. 5-azacytidine (5-AC; Vidaza), a global DNA methyltransferase inhibitor, was Food and Drug Administration approved to treat myelodysplastic syndromes and is clinically tested for solid tumors. In this paper, it was demonstrated that 5'-aza-2'-deoxycytidine (5-azaCdR) activated both silenced tumor suppressor genes and pro-metastatic genes by demethylation, raising the concern that it would promote metastasis. 5-AzaCdR treatment increased the invasiveness of non-invasive breast cancer cell lines MCF-7 cells and ZR-75-1 and dramatically induced pro-metastatic genes; Urokinase plasminogen activator (uPA), matrix metalloproteinase 2 (MMP2), metastasis-associated gene (H-MTS1; S100A4) and C-X-C chemokine receptor 4 (CXCR4). The hypothesis that the blocking of cellular transformation activity of DNA methyltransferase inhibitor could be separated from the pro-metastatic activity was tested using short interfering RNA (siRNA) targeted to the different DNA methyltransferase (DNMT) genes. Although depletion of DNMT1 had the strongest effect on colony growth suppression in cellular transformation assays, it did not result in demethylation and activation of uPA, S100A4, MMP2 and CXCR4 in MCF-7 cells. Depletion of DNMT1 did not induce cellular invasion in MCF-7 and ZR-75-1 non-invasive breast cancer cell lines. These data have implications on the design of new DNA methyltransferase inhibitor and on the proper utilization of current inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980350"}
{"pmid": "20980351", "title": "The effect of eccentric and concentric calf muscle training on Achilles tendon stiffness.", "content": "The effect of eccentric and concentric calf muscle training on Achilles tendon stiffness. To compare in vivo effects of eccentric and concentric calf muscle training on Achilles tendon stiffness, in subjects without tendinopathy. Thirty-eight recreational athletes completed 6 weeks eccentric (6 males, 13 females, 21.6  ±  2.2 years) or concentric training (8 males, 11 females, 21.1  ±  2.0 years). Achilles tendon stiffness, tendon modulus and single-leg jump height were measured before and after intervention. Exercise adherence was recorded using a diary. All data are reported as mean  ±  SD. Groups were matched for height and weight but the eccentric training group were more active at baseline (P < 0.05). Tendon stiffness was higher in the eccentrically trained group at baseline compared to the concentrically trained group (20.9  ±  7.3 N/mm v 13.38  ±  4.66 N/mm; P = 0.001) and decreased significantly after eccentric training (to 17.2 ( ±  5.9) N/mm (P = 0.035)). There was no stiffness change in the concentric group (P = 0.405). Stiffness modulus showed similar changes to stiffness. An inverse correlation was found between initial, and subsequent, reduction in stiffness (r = -0.66). Jump height did not change and no correlation between stiffness change and adherence was observed in either group (r = 0.01). Six weeks of eccentric training can alter Achilles tendon stiffness while a matched concentric programme shows no similar effects. Studies in patients with Achilles tendinopathy are warranted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980351"}
{"pmid": "20980352", "title": "Influence of magnetic knee wraps on joint proprioception in individuals with osteoarthritis: a randomized controlled pilot trial.", "content": "Influence of magnetic knee wraps on joint proprioception in individuals with osteoarthritis: a randomized controlled pilot trial. To determine the effects of magnetic knee wraps (MKWs) on joint position sense (JPS) in individuals with mild-to-moderate knee osteoarthritis. Randomized, double-blind, placebo-controlled pilot trial. Rehabilitation clinic of a tertiary hospital. Fifty volunteers with mild-to-moderate knee osteoarthritis participated and 33 (66%) completed the trial; only one (2%) withdrew due to study-related adverse effects. Knee wraps with a static magnetic field (35  mT) were compared with control knee wraps for 12 weeks. The main outcome measure was JPS at first, fourth, and twelfth week while applying of the knee wrap, quantified as the ability to replicate target knee joint angles. The secondary outcome was the Comprehensive Osteoarthritis Test (COAT) total score. In the intention-to-treat analysis with an alpha-level of 0.05, 12-week application of the MKWs did not significantly reduce the mean absolute error (MAE) of JPS (n = 18; P = 0.627); contrarily, the MAE was found to decrease significantly after wearing the sham MKWs (n = 20; P = 0.01). The COAT total score gradually improved in both groups (P < 0.05). When comparing the improvement of MAE and COAT total score at each follow-up between two groups, no significant differences were found; the maximal difference in the improvement of MAE between two groups was noted at week 12 (mean difference: 1.2°; 95% confidence interval -0.4 to 2.9; P = 0.144). In the per-protocol analysis, the study group showed better improvement in the COAT total score at week 12 (P = 0.033). The 35-mT MKWs could not significantly influence knee JPS in individuals with mild-to-moderate knee osteoarthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980352"}
{"pmid": "20980353", "title": "Effects of the protein kinase inhibitor PKC412 on gene expression and link to physiological effects in zebrafish Danio rerio eleuthero-embryos.", "content": "Effects of the protein kinase inhibitor PKC412 on gene expression and link to physiological effects in zebrafish Danio rerio eleuthero-embryos. To identify molecular effects of the antineoplastic agent protein kinase C inhibitor 412 (PKC412) (midostaurin), we applied gene expression profiling in zebrafish using whole-genome microarrays. Behavioral, developmental, and physiological effects were investigated in order to analyze for correlations between altered gene expression profiles with effects on development and physiology. Zebrafish blastula-stage embryos were exposed for 6 days postfertilization to nominal levels of 2 and 40 μg/l PKC412. Among the 259 and 511 altered transcripts at both concentrations, respectively, the expressions of genes involved in the circadian rhythm were further investigated. Alteration of swimming behavior was not observed. Pathways of interest affected by PKC412 were angiogenesis, apoptosis, DNA damage response, and response to oxidative stress. Angiogenesis was analyzed in double-transgenic zebrafish embryos Tg(fli1a:EGFP)y1;Tg(gata1:dsRed)sd2; no major defects were induced by PKC412 treatment at both concentrations. Apoptosis occurred in olfactory placodes of embryos exposed to 40 μg/l, and DNA damage was induced at both PKC412 concentrations. However, there were no significant effects on reactive oxygen species formation. This study leads to the conclusion that PKC412-induced alterations of gene transcripts are partly paralleled by physiological effects at high, but not at low PKC412 concentrations expected to be of environmental relevance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980353"}
{"pmid": "20980354", "title": "Bowel movement and constipation frequencies and the risk of colorectal cancer among men in the Netherlands Cohort Study on Diet and Cancer.", "content": "Bowel movement and constipation frequencies and the risk of colorectal cancer among men in the Netherlands Cohort Study on Diet and Cancer. The authors investigated the associations between bowel movement and constipation frequencies and colorectal cancer (CRC) endpoints among men in the Netherlands Cohort Study on Diet and Cancer (n = 58,279) and explored whether dietary fiber intake may modify associations. After 13.3 years (1986-1999), 1,207 CRC cases and 1,753 subcohort members were available for case-cohort analyses. Multivariate analyses showed a significantly increased hazard ratio for CRC overall and rectal cancer in men who reported having a bowel movement 1-2 times per day (second-highest category) as compared with once a day (CRC: hazard ratio (HR) = 1.29, 95% confidence interval (CI): 1.09, 1.53 (P(trend) < 0.001); rectal cancer: HR = 1.50, 95% CI: 1.15, 1.95 (P(trend) = 0.001)). Hazard ratios for CRC overall and rectal cancer were significantly decreased and lowest in men who reported suffering from constipation sometimes or more often versus never (CRC: HR = 0.76, 95% CI: 0.58, 0.98 (P(trend) = 0.02); rectal cancer: HR = 0.57, 95% CI: 0.35, 0.90 (P(trend) = 0.01)). No trends in the associations with proximal or distal colon cancer risk were observed. Interactions with dietary fiber intake were not significant. In this study, frequent bowel movements were associated with an increased risk of rectal cancer in men, and constipation was associated with a decreased risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980354"}
{"pmid": "20980356", "title": "Association of abdominal visceral adiposity and thigh sarcopenia with changes of arteriosclerosis in haemodialysis patients.", "content": "Association of abdominal visceral adiposity and thigh sarcopenia with changes of arteriosclerosis in haemodialysis patients. In haemodialysis (HD) patients, abdominal visceral fat is accumulated while lean body mass is decreased irrespective of their body mass indexes (BMI). However, it is poorly understood which changes of fat and muscle masses are more associated with changes of arteriosclerosis. We aimed at examining the associations of abdominal visceral fat and thigh muscle masses with markers of arteriosclerosis in chronic HD patients in a cross-sectional fashion. We measured abdominal visceral fat mass area (AVFA), abdominal subcutaneous fat mass area (ASFA), thigh muscle area (TMA) and TMA standardized for femoral shaft area (TMA/FSA) by computed tomography (CT) in 161 HD patients (age: 61 ± 11 years, time on HD: 12 ± 10 years, male/female = 113/48, non-diabetes/diabetes = 127/34). We also investigated carotid artery intima-media thickness (CA-IMT) using the ultrasound instrument, and brachial-ankle pulse wave velocity (baPWV), cardio-ankle vascular index (CAVI) and ankle-brachial pressure index (ABI) using the waveform device (CAVI-VaSera VS-1000). AVFA was significantly and positively related to CA-IMT in both non-diabetic (r = 0.23, P < 0.05) and diabetic HD patients (r = 0.38, P < 0.05). There was a significant and positive correlation between AVFA and hs-CRP in all patients (r = 0.26, P < 0.01). ASFA was also significantly correlated with CA-IMT (r = 0.53, P < 0.01) in diabetic HD patients. TMA/SFA ratio was negatively associated with CA-IMT (r = - 0.21, P < 0.05), while positively with ABI (r = 0.28, P < 0.01) in non-diabetic patients. TMA/SFA ratio was inversely related to baPWV (r = - 0.41, P < 0.01) and CAVI (r = - 0.41, P < 0.05) in diabetic HD patients. Multiple regression analysis revealed that AVFA was a significant determinant of CA-IMT. TMA/AFA was also significantly associated with CA-IMT, baPWV, CAVI and ABI. Accumulated abdominal visceral fat is associated with CA-IMT. In addition, reduced thigh muscle mass area is independently related to CA-IMT, baPWV, CAVI and ABI, suggesting that sarcopenia in the leg is closely associated with systemic changes of arteriosclerosis in HD patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980356"}
{"pmid": "20980357", "title": "Patterns of renal disease in Cape Town South Africa: a 10-year review of a single-centre renal biopsy database.", "content": "Patterns of renal disease in Cape Town South Africa: a 10-year review of a single-centre renal biopsy database. The patterns of glomerular diseases have been widely reported from different regional and national biopsy registries worldwide. However, there are scant studies on the epidemiology of biopsy-proven renal disease, particularly glomerular diseases in sub-Saharan Africa. We retrospectively analysed the reports of 1284 native renal biopsies, reviewed by the same pathologist and performed at the Groote Schuur Hospital in Cape Town from 1 January 2000 to 31 December 2009. The mean age of all the patients biopsied was 36.8 ± 14.0 years with 61.8% of the patients being under 40 years of age. There was a preponderance of females (54.8%). There were more coloured patients (53.7%) than blacks (42.2%) or whites (3.9%). The frequencies of clinical indications for a renal biopsy were nephrotic range proteinuria (52.5%), acute renal failure (21.3%), asymptomatic urinary abnormalities (13.6%), chronic renal failure (6.4%), acute nephritic syndrome (5.8%) and haematuria (0.3%). The frequencies of the primary glomerulonephritis (GN) include mesangiocapillary GN (20.4%), mesangial proliferative GN (19.2%), membranous GN (18.5%), crescentic and necrotizing GN (11.4%), focal and segmental glomerulosclerosis (10.5%), post-infectious GN (8.2%), minimal change disease (6.0%) and IgA nephropathy (5.8%). Lupus nephritis was the most frequent secondary glomerular disease (39.0%) and was also the most frequent cause of the nephrotic range proteinuria (17.2%). HIV-associated nephropathy increased from 6.6% in 2000 to 25.7% in 2009 (P < 0.0001). Our data are an important contribution to the epidemiology of renal disease in Africa. We hope that this will form the basis for developing a renal biopsy registry in South Africa and across the continent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980357"}
{"pmid": "20980355", "title": "Psychophysical dissection of genotype effects on human bitter perception.", "content": "Psychophysical dissection of genotype effects on human bitter perception. The purpose of this study was to define the effects of individual polymorphisms within the haplotypes of the TAS2R38 taste receptor gene on human bitter taste perception. A racially and ethnically diverse sample of children and adults (N = 980) was phenotyped for thresholds of 6-n-propylthiouracil (PROP) and genotyped for 3 polymorphisms of the TAS2R38 gene (A49P, V262A, I296V). Subjects were grouped according to their diplotype (i.e., specific combinations of haplotypes) and compared for PROP thresholds. By contrasting subjects with particular diplotypes, we found that in addition to A49P, V262A and I296V were related to the ability of the subjects to detect PROP. The V262A variant site affected the ability of subjects to detect mid-range concentrations of PROP, whereas the I296V variant site affected the ability of subjects to perceive PROP at the lowest concentration. These data agree with results from previous studies using cell-based assays for 2 variant sites (A49P and V262A) but not those for the I296V variant site. The reason for the discordant results is not known but it highlights the need for psychophysical as well as cell-based methods to understand the genotype-phenotype relationship for taste receptors. Human PROP sensitivity is determined by the combination of each of these 3 polymorphisms within the TAS2R38 gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980355"}
{"pmid": "20980358", "title": "Apparent renal disease due to elevated creatinine levels associated with the use of boldenone.", "content": "Apparent renal disease due to elevated creatinine levels associated with the use of boldenone. The widespread use of reporting estimated glomerular filtration rate (eGFR) alongside serum creatinine has led to a heightened appreciation of renal disease. However, creatinine is recognized as an insensitive marker of true GFR and therefore can lead to misdiagnosis of renal dysfunction in the absence of true pathology. We report the case of a 37-year-old male referred due to abnormal eGFR and creatinine in the absence of clinical signs, symptoms or other biochemical abnormalities of renal disease. Subsequent investigations based on a high index of suspicion for exogenous substance abuse led to a novel observation of significantly raised creatinine due to the presence of boldenone, an equine anabolic steroid commonly abused in body building.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980358"}
{"pmid": "20980359", "title": "Endothelial progenitor cells in patients on extracorporeal maintenance dialysis therapy.", "content": "Endothelial progenitor cells in patients on extracorporeal maintenance dialysis therapy. Chronic renal failure patients have a high cardiovascular disease burden, low numbers and impaired function of endothelial progenitor cells (EPCs). We hypothesized that enhanced uraemic toxin removal restores EPCs in haemodialysis patients. In a prospective, randomized, cross-over trial, 18 patients were subjected to 4 weeks of each low-flux haemodialysis, high-flux haemodialysis and haemodiafiltration differing in uraemic toxin removal. EPCs were determined at baseline and at the end of each 4-week period. A cohort of 16 healthy volunteers served as control. EPCs were studied after culture on fibronectin (CFU-Hill) and collagen-1 (ECFC). Dialysis patients had a lower number of ECFCs than in healthy controls (P < 0.001) and a reduced fraction of vital ECFCs (P < 0.05), whereas the formation of endothelial cell colonies (ECCs) was increased (P < 0.05). Different middle molecular uraemic toxin removal had no effects on EPC numbers. The number of prototypical EPCs (CD34( +)/VEGFR2-KDR( +)/CD45( -) ECFCs) was similar between patients and controls. Correlations of plasma C-reactive protein with ECC count, CFU-Hill colony count and CD34( +)/VEGFR2-KDR( +)/CD45( -) subpopulation of both ECFC and CFU-Hill cells were observed. Different middle molecule removal has no effect on EPCs. Reduced vitality and enhanced ECC formation suggest growth induction of impaired EPCs in chronic renal failure and are associated with inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980359"}
{"pmid": "20980360", "title": "Need for redesigning pharmacologic research in older individuals. A position statement of the Geriatric Working Group of the Agenzia Italiana del Farmaco (AIFA).", "content": "Need for redesigning pharmacologic research in older individuals. A position statement of the Geriatric Working Group of the Agenzia Italiana del Farmaco (AIFA).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980360"}
{"pmid": "20980362", "title": "Arabidopsis and Tobacco superman regulate hormone signalling and mediate cell proliferation and differentiation.", "content": "Arabidopsis and Tobacco superman regulate hormone signalling and mediate cell proliferation and differentiation. Arabidopsis thaliana superman (SUP) plays an important role during flower development by maintaining the boundary between stamens and carpels in the inner two whorls. It was proposed that SUP maintains this boundary by regulating cell proliferation in both whorls, as loss-of-function superman mutants produce more stamens at the expense of carpels. However, the cellular mechanism that underlies SUP function remains unknown. Here Arabidopsis or tobacco (Nicotiana tabacum) SUP was overexpressed in tobacco plants to substantiate SUP's role as a regulator of cell proliferation and boundary definition and provide evidence that its biological role may be mediated via hormonal changes. It was found that moderate levels of SUP stimulated cell growth and proliferation, whereas high levels were inhibitory. SUP stimulated auxin- and cytokinin-regulated processes, and cells overexpressing SUP displayed reduced hormone dependency for proliferation and regeneration into plants. SUP also induced proliferation of female traits in the second and third flower whorls and promoted differentiation of petaloid properties in sepals, further supporting a role for SUP as a boundary regulator. Moreover, cytokinin suppressed stamen development and promoted differentiation of carpeloid tissues, suggesting that SUP may regulate male and female development via its effect on cytokinin signalling. Taken together, these observations suggest a model whereby the effect of SUP on cell growth and proliferation involves the modulation of auxin- and cytokinin-regulated processes. Furthermore, differential SUP expression or different sensitivities of different cell types to SUP may determine whether SUP stimulates or suppresses their proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980362"}
{"pmid": "20980365", "title": "Developing an interactive website for adolescents with a mentally ill family member.", "content": "Developing an interactive website for adolescents with a mentally ill family member. Adolescents with a mentally ill parent are at high risk for developing a disorder themselves. It is widely recommended that these adolescents be provided with preventive interventions designed especially for them, but their avoidance of professional help is a common problem. Because most teenagers in Western societies use the World Wide Web as a means of social interaction, use of the Internet for reaching these young people would appear to be a promising option. In this article, the authors describe the development of Survivalkid.nl, an interactive, Internet-delivered, preventive intervention for supporting adolescents with a mentally ill family member. Usage statistics with regard to frequency and duration of visits and amount of activity during visits suggest that: (a) the target group has been better served than before the site was launched; and (b) we have accomplished our goal of expanding the range of support.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980365"}
{"pmid": "20980366", "title": "Reflections on the development of micronucleus assays.", "content": "Reflections on the development of micronucleus assays. These are personal reflections on the development of methods to use micronuclei as a measure of genetic damage and their use in research and in toxicology by four people who have been intimately involved with this work, a personal rather than a comprehensive history. About 6000 papers have been published using such methods in many tissues in vivo or in cultured cells of many organisms from plants to humans, but the majority of the work has been on mammalian erythrocytes and human lymphocytes, the areas in which we have worked primarily. Although this is by no means a complete history, those working in the field may be interested in some of the personal events that lie behind the development and acceptance of methods that are now standard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980366"}
{"pmid": "20980364", "title": "Is the Incredible Years programme effective for children with neuro-developmental disorders and for families with Social Services involvement in the \"real world\" of community CAMHS?", "content": "Is the Incredible Years programme effective for children with neuro-developmental disorders and for families with Social Services involvement in the \"real world\" of community CAMHS? Over the past few years parenting has become the focus for political attention in an attempt to tackle high levels of disruptive and anti-social behaviour. The Incredible Years (IY) programme (Webster-Stratton, 1999) is one of the parenting training packages that has been identified as a treatment of choice. There are, however, few studies available to demonstrate the clinical relevance in real world Child and Adolescent Mental Health Services (CAMHS) and even less knowledge about how children affected by a neuro-developmental disorder and families involved with Social Services can benefit. The BASIC IY videotape parent training programme was used for consecutive groups of parents across two neighbouring CAMH services (n = 128). Data were collected before and after intervention using the Eyberg Behaviour Checklist (Eyberg & Ross, 1978) and a number of Visual Analogue Scales. The effectiveness of the group was compared to that of other studies and the outcomes for two sub-groups--children with a neuro-developmental disorder and families with Social Services involvement--were evaluated. Statistically significantly post-intervention scores were found for all groups showing moderate to large effect sizes. The results are comparable to other effectiveness studies (e.g., Gardner, Barton, & Klimes, 2006; Scott, 2005). They also show that the IY is equally effective for children diagnosed with a neuro-developmental disorder and for families with multiple and complex needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980364"}
{"pmid": "20980368", "title": "Deuterons at energies of 10 MeV to 1 TeV: conversion coefficients for fluence-to-absorbed dose, equivalent dose, effective dose and gray equivalent, calculated using Monte Carlo radiation transport code MCNPX 2.7.C.", "content": "Deuterons at energies of 10 MeV to 1 TeV: conversion coefficients for fluence-to-absorbed dose, equivalent dose, effective dose and gray equivalent, calculated using Monte Carlo radiation transport code MCNPX 2.7.C. Conversion coefficients were calculated for fluence-to-absorbed dose, fluence-to-equivalent dose, fluence-to-effective dose and fluence-to-gray equivalent for isotropic exposure of an adult female and an adult male to deuterons ((2)H(+)) in the energy range 10 MeV-1 TeV (0.01-1000 GeV). Coefficients were calculated using the Monte Carlo transport code MCNPX 2.7.C and BodyBuilder™ 1.3 anthropomorphic phantoms. Phantoms were modified to allow calculation of the effective dose to a Reference Person using tissues and tissue weighting factors from 1990 and 2007 recommendations of the International Commission on Radiological Protection (ICRP) and gray equivalent to selected tissues as recommended by the National Council on Radiation Protection and Measurements. Coefficients for the equivalent and effective dose incorporated a radiation weighting factor of 2. At 15 of 19 energies for which coefficients for the effective dose were calculated, coefficients based on ICRP 1990 and 2007 recommendations differed by <3%. The greatest difference, 47%, occurred at 30 MeV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980368"}
{"pmid": "20980367", "title": "Mutagenicity of 11 cigarette smoke condensates in two versions of the mouse lymphoma assay.", "content": "Mutagenicity of 11 cigarette smoke condensates in two versions of the mouse lymphoma assay. Cigarette smoke condensate (CSC) is genotoxic in nearly all assays in which it has been tested. In this study, we investigated the mutagenicity of 11 CSCs using the microwell and soft-agar versions of the mouse lymphoma assay (MLA). These CSCs were prepared from commercial or experimental cigarettes, 10 of them were produced using International Organisation for Standardisation (ISO) conditions and one CSC was generated using intense Massachusetts Department of Public Health (MDPH) conditions. In the presence of rat liver S9, the L5178Y/Tk(+/-) mouse lymphoma cells were treated with 11 CSCs at different concentrations (25-200 μg/ml) for 4 h. All CSCs resulted in dose-dependent increases of both cytotoxicity and mutagenicity in both versions of the MLA. The mutagenic potencies of the CSCs were calculated as mutant frequency per microgram CSC from the slope of the linear regression of the dose-response curves and showed no correlations with the tar yield of the cigarette or nicotine concentrations of the CSCs. Comparing two CSCs produced from the same commercial cigarettes using two different smoking conditions, the one generated under ISO conditions was more mutagenic than the other generated under intense conditions on a per microgram CSC basis. We also examined the loss of heterozygosity (LOH) at four microsatellite loci spanning the entire chromosome 11 for the mutants induced by 11 CSCs. The most common type of mutation observed was LOH with chromosome damage spanning less than ∼34 Mbp. These results indicate that the MLA identifies different genotoxic potencies among a variety of CSCs and that the results from both versions of the assay are comparable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980367"}
{"pmid": "20980369", "title": "More daylight, better health: why we shouldn't be putting the clocks back this weekend.", "content": "More daylight, better health: why we shouldn't be putting the clocks back this weekend.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980369"}
{"pmid": "20980370", "title": "Doctors are key to welfare reform.", "content": "Doctors are key to welfare reform.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980370"}
{"pmid": "20980363", "title": "Population genetic structure in german cockroaches (blattella germanica): differentiated islands in an agricultural landscape.", "content": "Population genetic structure in german cockroaches (blattella germanica): differentiated islands in an agricultural landscape. Although a number of species live syanthropically with humans, few rely entirely on humans for their survival and distribution. Unlike other cosmopolitan human commensals, the German cockroach (Blattella germanica), an insect of both public and livestock health concern, is considered incapable of dispersal outside human dwellings. Patterns of genetic association are therefore constrained and may not be associated with distance. Analogies with other human-commensal species are therefore impossible to draw with any degree of accuracy. In the past 2 decades, B. germanica has become a prominent pest within the US swine production system. Swine production is mainly carried out through contracted producers, each associated with a management company. It has been hypothesized that cockroach populations will be genetically structured based on association to a specific management company. Here, we tested this hypothesis using microsatellite genotypes (8 polymorphic loci) from 626 individual cockroaches collected from 22 farms in southeastern North Carolina representing 3 management companies. Significant genetic differentiation was detected (F(ST) = 0.171), most of which was partitioned among the 22 farms rather than the 3 management groups. All pair-wise population comparisons yielded F(ST) values significantly greater than zero. Our results reveal that structure does not correspond to management company of origin, but instead it may be regional and influenced strongly by the unintentional movement of cockroaches by farm workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980363"}
{"pmid": "20980375", "title": "Management of bedwetting in children and young people: summary of NICE guidance.", "content": "Management of bedwetting in children and young people: summary of NICE guidance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980375"}
{"pmid": "20980376", "title": "Effect of repeated invitations on uptake of colorectal cancer screening using faecal occult blood testing: analysis of prevalence and incidence screening.", "content": "Effect of repeated invitations on uptake of colorectal cancer screening using faecal occult blood testing: analysis of prevalence and incidence screening. To analyse the effects of prevalence and incidence screening on uptake and detection of cancer in an ongoing, dynamic programme for colorectal screening using faecal occult blood testing. Analysis of prevalence and incidence screening. Three rounds of biennial colorectal screening using the guaiac faecal occult blood test in east and north east Scotland, March 2000 to May 2007. Adults aged 50-69. Uptake of screening, test positivity (percentage of those invited who returned a test that was positive and triggered an invitation for colonoscopy), positive predictive value, and stage of cancer. Of 510 990 screening episodes in all three rounds, 248 998 (48.7%) were for prevalence, 163 483 (32.0%) were for first incidence, and 98 509 (19.3%) were for second incidence. Uptake of a first invitation for prevalence screening was 53% and for a second and third invitation was 15% and 12%. In the cohort invited for the first round, uptake of prevalence screening rose from 55% in the first round to 63% in the third. The uptake of first incidence screening on a first invitation was 54% and on a second invitation was 86% and on a first invitation for second incidence screening was 46%. The positivity rate in prevalence screening was 1.9% and the uptake of colonoscopy was 87%. The corresponding values for a first incidence screen were 1.7% and 90% and for a second incidence screen were 1.1% and 94.5%. The positive predictive value of a positive faecal occult blood test result for cancer was 11.0% for prevalence screening, 6.5% for the first incidence screen, and 7.5% for the second incidence screen. The corresponding values for the positive predictive value for adenoma were 35.5%, 29.4%, and 26.7%. The proportion of cancers at stage I dropped from 46.5% for prevalence screening to 41% for first incidence screening and 35% for second incidence screening. Repeat invitations to those who do not take up the offer of screening increases the number of those who accept, for both prevalence screening and incidence screening. Although the positive predictive value for both cancer and adenomas fell between the prevalence screen and the first incidence screen, they did not fall between the first and second incidence screens. The deterioration in cancer stage from prevalence to incidence screening suggests that some cancers picked up at incidence screening may have been missed on prevalence screening, but the stage distribution is still favourable. These data vindicate the policies of continuing to offer screening to those who fail to participate and continuing to offer biennial screening to those who have accepted previous offers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980376"}
{"pmid": "20980378", "title": "The impact of the spending review on health and social care.", "content": "The impact of the spending review on health and social care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980378"}
{"pmid": "20980379", "title": "Are the spending cuts fair? Yes.", "content": "Are the spending cuts fair? Yes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980379"}
{"pmid": "20980380", "title": "New international guidelines on resuscitation.", "content": "New international guidelines on resuscitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980380"}
{"pmid": "20980381", "title": "Are the spending cuts fair? No.", "content": "Are the spending cuts fair? No.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980381"}
{"pmid": "20980385", "title": "Dynamic instability of the intracellular pressure drives bleb-based motility.", "content": "Dynamic instability of the intracellular pressure drives bleb-based motility. We have demonstrated that the two- and three-dimensional motility of the human pathogenic parasite Entamoeba histolytica (Eh) depends on sustained instability of the intracellular hydrostatic pressure. This instability drives the cyclic generation and healing of membrane blebs, with typical protrusion velocities of 10-20 μm/second over a few hundred milliseconds and healing times of 10 seconds. The use of a novel micro-electroporation method to control the intracellular pressure enabled us to develop a qualitative model with three parameters: the rate of the myosin-driven internal pressure increase; the critical disjunction stress of membrane-cytoskeleton bonds; and the turnover time of the F-actin cortex. Although blebs occur randomly in space and irregularly time, they can be forced to occur with a defined periodicity in confined geometries, thus confirming our model. Given the highly efficient bleb-based motility of Eh in vitro and in vivo, Eh cells represent a unique model for studying the physical and biological aspects of amoeboid versus mesenchymal motility in two- and three-dimensional environments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980385"}
{"pmid": "20980384", "title": "Competition between SOCS36E and Drk modulates Sevenless receptor tyrosine kinase activity.", "content": "Competition between SOCS36E and Drk modulates Sevenless receptor tyrosine kinase activity. Modulation of signalling pathways can trigger different cellular responses, including differences in cell fate. This modulation can be achieved by controlling the pathway activity with great precision to ensure robustness and reproducibility of the specification of cell fate. The development of the photoreceptor R7 in the Drosophila melanogaster retina has become a model in which to investigate the control of cell signalling. During R7 specification, a burst of Ras small GTPase (Ras) and mitogen-activated protein kinase (MAPK) controlled by Sevenless receptor tyrosine kinase (Sev) is required. Several cells in each ommatidium express sev. However, the spatiotemporal expression of the boss ligand and the action of negative regulators of the Sev pathway will restrict the R7 fate to a single cell. The Drosophila suppressor of cytokine signalling 36E (SOCS36E) protein contains an SH2 domain and acts as a Sev signalling attenuator. By contrast, downstream of receptor kinase (Drk), the fly homolog of the mammalian Grb2 adaptor protein, which also contains an SH2 domain, acts as a positive activator of the pathway. Here, we apply the Förster resonance energy transfer (FRET) assay to transfected Drosophila S2 cells and demonstrate that Sev binds directly to either the suppressor protein SOCS36E or the adaptor protein Drk. We propose a mechanistic model in which the competition between these two proteins for binding to the same docking site results in either attenuation of the Sev transduction in cells that should not develop R7 photoreceptors or amplification of the Ras-MAPK signal only in the R7 precursor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980384"}
{"pmid": "20980386", "title": "Specific proteolytic cleavage of agrin regulates maturation of the neuromuscular junction.", "content": "Specific proteolytic cleavage of agrin regulates maturation of the neuromuscular junction. During the initial stage of neuromuscular junction (NMJ) formation, nerve-derived agrin cooperates with muscle-autonomous mechanisms in the organization and stabilization of a plaque-like postsynaptic specialization at the site of nerve-muscle contact. Subsequent NMJ maturation to the characteristic pretzel-like appearance requires extensive structural reorganization. We found that the progress of plaque-to-pretzel maturation is regulated by agrin. Excessive cleavage of agrin via transgenic overexpression of an agrin-cleaving protease, neurotrypsin, in motoneurons resulted in excessive reorganizational activity of the NMJs, leading to rapid dispersal of the synaptic specialization. By contrast, expression of cleavage-resistant agrin in motoneurons slowed down NMJ remodeling and delayed NMJ maturation. Neurotrypsin, which is the sole agrin-cleaving protease in the CNS, was excluded as the physiological agrin-cleaving protease at the NMJ, because NMJ maturation was normal in neurotrypsin-deficient mice. Together, our analyses characterize agrin cleavage at its proteolytic α- and β-sites by an as-yet-unspecified protease as a regulatory access for relieving the agrin-dependent constraint on endplate reorganization during NMJ maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980386"}
{"pmid": "20980382", "title": "ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.", "content": "ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site. Protein ectodomain shedding is crucial for cell-cell interactions because it controls the bioavailability of soluble tumor necrosis factor-α (TNFα) and ligands of the epidermal growth factor (EGF) receptor, and the release of many other membrane proteins. Various stimuli can rapidly trigger ectodomain shedding, yet much remains to be learned about the identity of the enzymes that respond to these stimuli and the mechanisms underlying their activation. Here, we demonstrate that the membrane-anchored metalloproteinase ADAM17, but not ADAM10, is the sheddase that rapidly responds to the physiological signaling pathways stimulated by thrombin, EGF, lysophosphatidic acid and TNFα. Stimulation of ADAM17 is swift and quickly reversible, and does not depend on removal of its inhibitory pro-domain by pro-protein convertases, or on dissociation of an endogenous inhibitor, TIMP3. Moreover, activation of ADAM17 by physiological stimuli requires its transmembrane domain, but not its cytoplasmic domain, arguing against inside-out signaling via cytoplasmic phosphorylation as the underlying mechanism. Finally, experiments with the tight binding hydroxamate inhibitor DPC333, used here to probe the accessibility of the active site of ADAM17, demonstrate that this inhibitor can quickly bind to ADAM17 in stimulated, but not quiescent cells. These findings support the concept that activation of ADAM17 involves a rapid and reversible exposure of its catalytic site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980382"}
{"pmid": "20980383", "title": "The AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport.", "content": "The AP-1 clathrin adaptor facilitates cilium formation and functions with RAB-8 in C. elegans ciliary membrane transport. Clathrin adaptor (AP) complexes facilitate membrane trafficking between subcellular compartments. One such compartment is the cilium, whose dysfunction underlies disorders classified as ciliopathies. Although AP-1mu subunit (UNC-101) is linked to cilium formation and targeting of transmembrane proteins (ODR-10) to nematode sensory cilia at distal dendrite tips, these functions remain poorly understood. Here, using Caenorhabditis elegans sensory neurons and mammalian cell culture models, we find conservation of AP-1 function in facilitating cilium morphology, positioning and orientation, and microtubule stability and acetylation. These defects appear to be independent of IFT, because AP-1-depleted cells possess normal IFT protein localisation and motility. By contrast, disruption of chc-1 (clathrin) or rab-8 phenocopies unc-101 worms, preventing ODR-10 vesicle formation and causing misrouting of ODR-10 to all plasma membrane destinations. Finally, ODR-10 colocalises with RAB-8 in cell soma and they cotranslocate along dendrites, whereas ODR-10 and UNC-101 signals do not overlap. Together, these data implicate conserved roles for metazoan AP-1 in facilitating cilium structure and function, and suggest cooperation with RAB-8 to coordinate distinct early steps in neuronal ciliary membrane sorting and trafficking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980383"}
{"pmid": "20980387", "title": "Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation.", "content": "Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation. The proto-oncogene Src tyrosine kinase (Src) is overexpressed in human cancers and is currently a target of anti-invasive therapies. Activation of Src is an essential catalyst of invadopodia production. Invadopodia are cellular structures that mediate extracellular matrix (ECM) proteolysis, allowing invasive cell types to breach confining tissue barriers. Invadopodia assembly and maturation is a multistep process, first requiring the targeting of actin-associated proteins to form pre-invadopodia, which subsequently mature by recruitment and activation of matrix metalloproteases (MMPs) that facilitate ECM degradation. We demonstrate that active, oncogenic Src alleles require the presence of a wild-type counterpart to induce ECM degradation at invadopodia sites. In addition, we identify the phosphorylation of the invadopodia regulatory protein cortactin as an important mediator of invadopodia maturation downstream of wild-type Src. Distinct phosphotyrosine-based protein-binding profiles in cells forming pre-invadopodia and mature invadopodia were identified by SH2-domain array analysis. These results indicate that although elevated Src kinase activity is required to target actin-associated proteins to pre-invadopodia, regulated Src activity is required for invadopodia maturation and matrix degradation activity. Our findings describe a previously unappreciated role for proto-oncogenic Src in enabling the invasive activity of constitutively active Src alleles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980387"}
{"pmid": "20980388", "title": "The AP-1 family member FOS blocks transcriptional activity of the nuclear receptor steroidogenic factor 1.", "content": "The AP-1 family member FOS blocks transcriptional activity of the nuclear receptor steroidogenic factor 1. Steroid production in the adrenal zona glomerulosa is under the control of angiotensin II (Ang II), which, upon binding to its receptor, activates protein kinase C (PKC) within these cells. PKC is a potent inhibitor of the steroidogenic enzyme CYP17. We have demonstrated that, in the ovary, PKC activates expression of FOS, a member of the AP-1 family, and increased expression of this gene is linked to CYP17 downregulation. However, the pathway and the molecular mechanism responsible for the inhibitory effect of PKC on CYP17 expression are not defined. Herein, we demonstrated that Ang II inhibited CYP17 through PKC and ERK1/2-activated FOS and that blocking FOS expression decreased PKC-mediated inhibition. Although CYP17 transcription was activated by the nuclear receptor SF-1, expression of FOS resulted in a decrease in SF-1-mediated gene transcription. FOS physically interacted with the hinge region of SF-1 and modulated its transactivity, thus preventing binding of cofactors such as SRC1 and CBP, which were necessary to fully activate CYP17 transcription. Collectively, these results indicate a new regulatory mechanism for SF-1 transcriptional activity that might influence adrenal zone-specific expression of CYP17, a mechanism that can potentially be applied to other steroidogenic tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980388"}
{"pmid": "20980389", "title": "Kinectin-mediated endoplasmic reticulum dynamics supports focal adhesion growth in the cellular lamella.", "content": "Kinectin-mediated endoplasmic reticulum dynamics supports focal adhesion growth in the cellular lamella. Focal adhesions (FAs) control cell shape and motility, which are important processes that underlie a wide range of physiological functions. FA dynamics is regulated by cytoskeleton, motor proteins and small GTPases. Kinectin is an integral endoplasmic reticulum (ER) membrane protein that extends the ER along microtubules. Here, we investigated the influence of the ER on FA dynamics within the cellular lamella by disrupting the kinectin-kinesin interaction by overexpressing the minimal kinectin-kinesin interaction domain on kinectin in cells. This perturbation resulted in a morphological change to a rounded cell shape and reduced cell spreading and migration. Immunofluorescence and live-cell imaging demonstrated a kinectin-dependent ER extension into the cellular lamella and ER colocalisation with FAs within the cellular lamella. FRAP experiments showed that ER contact with FAs was accompanied with an increase in FA protein recruitment to FAs. Disruption of the kinectin-kinesin interaction caused a reduction in FA protein recruitment to FAs. This suggests that the ER supports FA growth within the cellular lamella. Microtubule targeting to FAs is known to promote adhesion disassembly; however, ER contact increased FA size even in the presence of microtubules. Our results suggest a scenario whereby kinectin-kinesin interaction facilitates ER transport along microtubules to support FA growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980389"}
{"pmid": "20980390", "title": "Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGFβ1 levels and RhoA activity.", "content": "Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGFβ1 levels and RhoA activity. Wound healing crucially relies on the mechanical activity of fibroblasts responding to TGFβ1 and to forces transmitted across focal adhesions. Integrin-linked kinase (ILK) is a central adapter recruited to integrin β1 tails in focal adhesions mediating the communication between cells and extracellular matrix. Here, we show that fibroblast-restricted inactivation of ILK in mice leads to impaired healing due to a severe reduction in the number of myofibroblasts, whereas inflammatory infiltrate and vascularization of the granulation tissue are unaffected. Primary ILK-deficient fibroblasts exhibit severely reduced levels of extracellular TGFβ1, α-smooth muscle actin (αSMA) production and myofibroblast conversion, which are rescued by exogenous TGFβ1. They are further characterized by elevated RhoA and low Rac1 activities, resulting in abnormal shape and reduced directional migration. Interference with RhoA-ROCK signaling largely restores morphology, migration and TGFβ1 levels. We conclude that, in fibroblasts, ILK is crucial for limiting RhoA activity, thus promoting TGFβ1 production, which is essential for dermal repair following injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980390"}
{"pmid": "20980391", "title": "Autocrine fibronectin directs matrix assembly and crosstalk between cell-matrix and cell-cell adhesion in vascular endothelial cells.", "content": "Autocrine fibronectin directs matrix assembly and crosstalk between cell-matrix and cell-cell adhesion in vascular endothelial cells. Cellular fibronectin (cFN) variants harboring extra FN type 3 repeats, namely extra domains B and A, are major constituents of the extracellular matrix around newly forming blood vessels during development and angiogenesis. Their expression is induced by angiogenic stimuli and their assembly into fibrillar arrays is driven by cell-generated tension at α5β1 integrin-based adhesions. Here, we examined the role and functional redundancy of cFN variants in cultured endothelial cells by isoform-selective RNA interference. We show that FN fibrillogenesis is a cell-autonomous process whereby basally directed secretion and assembly of cellular FN are tightly coupled events that play an important role not only in signaling at cell-matrix adhesions but also at cell-cell contacts. Silencing of cFN variants differentially affects integrin usage, cell spreading, motility and capillary morphogenesis in vitro. cFN-deficient cells undergo a switch from α5β1- to αvβ3-based adhesion, accompanied by a Src-regulated disruption of adherens junctions. These studies identify a crucial role for autocrine FN in subendothelial matrix assembly and junctional integrity that provides spatially and temporally restricted control of endothelial plasticity during angiogenic blood vessel remodeling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980391"}
{"pmid": "20980393", "title": "Specific phosphorylation of Ser458 of A-type lamins in LMNA-associated myopathy patients.", "content": "Specific phosphorylation of Ser458 of A-type lamins in LMNA-associated myopathy patients. Mutations in LMNA, which encodes A-type nuclear lamins, cause various human diseases, including myopathy, cardiomyopathy, lipodystrophy and progeria syndrome. To date, little is known about how mutations in a single gene cause a wide variety of diseases. Here, by characterizing an antibody that specifically recognizes the phosphorylation of Ser458 of A-type lamins, we uncover findings that might contribute to our understanding of laminopathies. This antibody only reacts with nuclei in muscle biopsies from myopathy patients with mutations in the Ig-fold motif of A-type lamins. Ser458 phosphorylation is not seen in muscles from control patients or patients with any other neuromuscular diseases. In vitro analysis confirmed that only lamin A mutants associated with myopathy induce phosphorylation of Ser458, whereas lipodystrophy- or progeria-associated mutants do not. We also found that Akt1 directly phosphorylates Ser458 of lamin A with myopathy-related mutations in vitro. These results suggest that Ser458 phosphorylation of A-type lamins correlates with striated muscle laminopathies; this might be useful for the early diagnosis of LMNA-associated myopathies. We propose that disease-specific phosphorylation of A-type lamins by Akt1 contributes to myopathy caused by LMNA mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980393"}
{"pmid": "20980394", "title": "Cdc14p resets the competency of replication licensing by dephosphorylating multiple initiation proteins during mitotic exit in budding yeast.", "content": "Cdc14p resets the competency of replication licensing by dephosphorylating multiple initiation proteins during mitotic exit in budding yeast. In eukaryotes, replication licensing is achieved through sequential loading of several replication-initiation proteins onto replication origins to form pre-replicative complexes (pre-RCs), and unscheduled replication licensing is prevented by cyclin-dependent kinases (CDKs) through inhibitory phosphorylations of multiple initiation proteins. It is known that CDK inactivation during mitotic exit promotes pre-RC formation for the next cell cycle. However, whether the removal of the inhibitory phosphorylations on the initiation proteins is essential and the identity of the acting phosphatase(s) remain unknown. Here, we show that cell division cycle protein 14 (Cdc14p) dephosphorylates replication-initiation proteins Orc2p, Orc6p, Cdc6p and Mcm3p to restore their competence for pre-RC assembly in the budding yeast Saccharomyces cerevisiae. Cells without functional Cdc14p fail to dephosphorylate initiation proteins and to form pre-RCs - even when CDK activities are suppressed - and cannot replicate DNA in mitotic rereplication systems, whereas pulsed ectopic expression of Cdc14p in mitotic cells results in efficient pre-RC assembly and DNA rereplication. Furthermore, Cdc14p becomes dispensable for DNA rereplication in mitotic cells with combined non-phosphorylatable and/or phosphorylation-insensitive alleles of the initiation proteins. These data unravel the essential role of Cdc14p in replication licensing, beyond its established functions in mitotic exit, providing new insight into the intricate regulation of DNA replication through the interplay of CDKs and the Cdc14p phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980394"}
{"pmid": "20980395", "title": "A hypoglycaemic baby on the postnatal ward.", "content": "A hypoglycaemic baby on the postnatal ward.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980395"}
{"pmid": "20980392", "title": "Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress.", "content": "Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress. ATF1 (activating transcription factor 1), a stimulus-induced CREB family transcription factor, plays important roles in cell survival and proliferation. Phosphorylation of ATF1 at Ser63 by PKA (cAMP-dependent protein kinase) and related kinases was the only known post-translational regulatory mechanism of ATF1. Here, we found that HIPK2 (homeodomain-interacting protein kinase 2), a DNA-damage-responsive nuclear kinase, is a new ATF1 kinase that phosphorylates Ser198 but not Ser63. ATF1 phosphorylation by HIPK2 activated ATF1 transcription function in the GAL4-reporter system. ATF1 is a transcriptional repressor of ferritin H, the major intracellular iron storage gene, through an ARE (antioxidant-responsive element). HIPK2 overrode the ATF1-mediated ARE repression in a kinase-activity-dependent manner in HepG2 cells. Furthermore, DNA-damage-inducing agents doxorubicin, etoposide and sodium arsenite induced ferritin H mRNA expression in HIPK2(+/+) MEF cells, whereas it was significantly impaired in HIPK2(-/-) MEF cells. Induction of other ARE-regulated detoxification genes such as NQO1 (NADPH quinone oxidoreductase 1), GST (glutathione S-transferase) and HO1 (heme oxygenase 1) by genotoxic stress was also decreased in HIPK2-deficient cells. Taken together, these results suggest that HIPK2 is a new ATF1 kinase involved in the regulation of ferritin H and other antioxidant detoxification genes in genotoxic stress conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980392"}
{"pmid": "20980399", "title": "The influence of health behaviors on survival in lung cancer patients in Taiwan.", "content": "The influence of health behaviors on survival in lung cancer patients in Taiwan. It is well known that patients' health risk behavior will affect the survival outcome of diseases. Smoking alone is a significant health risk behavior that affects the survival outcome of lung cancers; other health risk behaviors remained unknown. Therefore, this study discusses the effects of health risk behaviors on the survival outcome in lung cancer patients. The study sample consists of 1410 newly diagnosed, histologically confirmed lung cancer patients from a medical center hospital in central Taiwan. The patient medical records were collected from 1 January 1998 to May 2004. Besides descriptive statistical analyses, t-test and analysis of variance were used to analyze the relationship between patient characteristics, patient health risk behavior and survival. Chi-square tests were used to analyze the relationship between patient characteristics, patient health risk behavior and stage of disease. Cox's proportional hazards regression was computed for the risk of survival by patient characteristics and patient health risk behavior. The results showed that there is a significant difference between smoking (P < 0.001), alcohol consumption (P = 0.027), routine physical check-ups (out-of-pocket) (P < 0.001) and survival time. Patients with betel-nut consumption did not have a significant effect upon survival than non-betel-nut consumption patients. When holding constants all the variables in Cox's proportional hazards model, smoking (P = 0.02), routine physical check-ups (out-of-pocket) (P = 0.017) and stage at diagnosis of lung cancer (P < 0.001) will affect lung cancer patients' survival. This study presented evidence showing that smoking, alcohol consumption behavior, routine physical check-ups and stage at diagnosis play an important role in determining the survival of lung cancer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980399"}
{"pmid": "20980400", "title": "TIAR and TIA-1 mRNA-binding proteins co-aggregate under conditions of rapid oxygen decline and extreme hypoxia and suppress the HIF-1α pathway.", "content": "TIAR and TIA-1 mRNA-binding proteins co-aggregate under conditions of rapid oxygen decline and extreme hypoxia and suppress the HIF-1α pathway. T-cell intracellular antigen (TIA)-1 and TIA-1-related protein (TIAR) are mRNA-binding proteins that can aggregate within granules under specific stress conditions. In this study, we analyzed TIAR/TIA-1 aggregation under different hypoxic conditions, and studied the effects on the hypoxia-inducible factor (HIF)-1α in different cancer cell lines. Under acute and pronounced hypoxic conditions TIAR/TIA-1 co-aggregated to granules and positive co-staining with eIF3η marker suggested these to represent stress granules. In parallel, HIF-1α expression was blocked in cells displaying TIAR/TIA-1 granules. Silencing of TIAR and TIA-1 caused upregulation of HIF-1α expression, as demonstrated by western blot, immunocytochemistry and HIF-1-dependent reporter gene expression. Additionally, a critical region of the 3' end of the untranslated HIF-1α mRNA with possible adenosine-uridine-rich elements (AREs) was coupled to the luciferase reporter gene, causing downregulation of expression. Employing this reporter construct, inhibition of TIAR by siRNA attenuated the inhibitory cis-effect of this ARE-sequence. Furthermore, immunohistochemical analysis of A549 cell tumor xenografts revealed a nearly complementary expression of HIF-1α and TIAR reflecting the control of HIF-1α expression by TIAR as revealed in the cell culture studies. In sum, rapid and severe hypoxia caused co-aggregation of TIAR/TIA-1 and these proteins suppressed HIF-1α expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980400"}
{"pmid": "20980401", "title": "Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse.", "content": "Regulation of hematopoietic cell clusters in the placental niche through SCF/Kit signaling in embryonic mouse. Hematopoietic stem cells (HSCs) emerge from and expand in the mouse placenta at mid-gestation. To determine their compartment of origin and define extrinsic signals governing their commitment to this lineage, we identified hematopoietic cell (HC) clusters in mouse placenta, defined as cells expressing the embryonic HSC markers CD31, CD34 and Kit, by immunohistochemistry. HC clusters were first observed in the placenta at 9.5 days post coitum (dpc). To determine their origin, we tagged the allantoic region with CM-DiI at 8.25 dpc, prior to placenta formation, and cultured embryos in a whole embryo culture (WEC) system. CM-DiI-positive HC clusters were observed 42 hours later. To determine how clusters are extrinsically regulated, we isolated niche cells using laser capture micro-dissection and assayed them for expression of genes encoding hematopoietic cytokines. Among a panel of candidates assayed, only stem cell factor (SCF) was expressed in niche cells. To define niche cells, endothelial and mesenchymal cells were sorted by flow cytometry from dissociated placenta and hematopoietic cytokine gene expression was investigated. The endothelial cell compartment predominantly expressed SCF mRNA and protein. To determine whether SCF/Kit signaling regulates placental HC cluster proliferation, we injected anti-Kit neutralizing antibody into 10.25 dpc embryos and assayed cultured embryos for expression of hematopoietic transcription factors. Runx1, Myb and Gata2 were downregulated in the placental HC cluster fraction relative to controls. These observations demonstrate that placental HC clusters originate from the allantois and are regulated by endothelial niche cells through SCF/Kit signaling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980401"}
{"pmid": "20980402", "title": "Clonal analyses reveal roles of organ founding stem cells, melanocyte stem cells and melanoblasts in establishment, growth and regeneration of the adult zebrafish fin.", "content": "Clonal analyses reveal roles of organ founding stem cells, melanocyte stem cells and melanoblasts in establishment, growth and regeneration of the adult zebrafish fin. In vertebrates, the adult form emerges from the embryo by mobilization of precursors or adult stem cells. What different cell types these precursors give rise to, how many precursors establish the tissue or organ, and how they divide to establish and maintain the adult form remain largely unknown. We use the pigment pattern of the adult zebrafish fin, with a variety of clonal and lineage analyses, to address these issues. Early embryonic labeling with lineage-marker-bearing transposons shows that all classes of fin melanocytes (ontogenetic, regeneration and kit-independent melanocytes) and xanthophores arise from the same melanocyte-producing founding stem cells (mFSCs), whereas iridophores arise from distinct precursors. Additionally, these experiments show that, on average, six and nine mFSCs colonize the caudal and anal fin primordia, and daughters of different mFSCs always intercalate to form the adult pattern. Labeled clones are arrayed along the proximal-distal axis of the fin, and melanocyte time-of-differentiation lineage assays show that although most of the pigment pattern growth is at the distal edge of the fin, significant growth also occurs proximally. This suggests that leading edge melanocyte stem cells (MSCs) divide both asymmetrically to generate new melanocytes, and symmetrically to expand the MSCs and leave quiescent MSCs in their wake. Clonal labeling in adult stages confirms this and reveals different contributions of MSCs and transient melanoblasts during growth. These analyses build a comprehensive picture for how MSCs are established and grow to form the pigment stripes of the adult zebrafish fins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980402"}
{"pmid": "20980403", "title": "Klf5 regulates lineage formation in the pre-implantation mouse embryo.", "content": "Klf5 regulates lineage formation in the pre-implantation mouse embryo. Kruppel-like transcription factors (Klfs) are essential for the induction and maintenance of pluripotency of embryonic stem cells (ESCs), yet little is known about their roles in establishing the three lineages of the pre-implantation embryo. Here, we show that Klf5 is required for the formation of the trophectoderm (TE) and the inner cell mass (ICM), and for repressing primitive endoderm (PE) development. Although cell polarity appeared normal, Klf5 mutant embryos arrested at the blastocyst stage and failed to hatch due to defective TE development. Klf5 acted cell-autonomously in the TE, downstream of Fgf4 and upstream of Cdx2, Eomes and Krt8. In the ICM, loss of Klf5 resulted in reduced expression of pluripotency markers Oct4 and Nanog, but led to increased Sox17 expression in the PE, suggesting that Klf5 suppresses the PE lineage. Consistent with this, overexpression of Klf5 in transgenic embryos was sufficient to suppress the Sox17(+) PE lineage in the ICM. Klf5 overexpression led to a dose-dependent decrease in Sox17 promoter activity in reporter assays in cultured cells. Moreover, in chimeric embryos, Klf5(-/-) cells preferentially contributed to the Sox17(+) PE lineage and Cdx2 expression was not rescued in Klf5(-/-) outer cells. Finally, outgrowths from Klf5(-/-) embryos failed to form an ICM/pluripotent colony, had very few Oct4(+) or Cdx2(+) cells, but showed an increase in the percentage of Sox17(+) PE cells. These findings demonstrate that Klf5 is a dynamic regulator of all three lineages in the pre-implantation embryo by promoting the TE and epiblast lineages while suppressing the PE lineage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980403"}
{"pmid": "20980406", "title": "Glyceraldehyde 3-phosphate dehydrogenase is required for band 3 (anion exchanger 1) membrane residency in the mammalian kidney.", "content": "Glyceraldehyde 3-phosphate dehydrogenase is required for band 3 (anion exchanger 1) membrane residency in the mammalian kidney. The mammalian kidney isoform of the essential chloride-bicarbonate exchanger AE1 differs from its erythrocyte counterpart, being shorter at its N terminus. It has previously been reported that the glycolytic enzyme GAPDH interacts only with erythrocyte AE1, by binding to the portion not found in the kidney isoform. (Chu H, Low PS. Biochem J 400:143-151, 2006). We have identified GAPDH as a candidate binding partner for the C terminus of both AE1 and AE2. We show that full-length AE1 and GAPDH coimmunoprecipitated from both human and rat kidney as well as from Madin-Darby canine kidney (MDCK) cells stably expressing kidney AE1, while in human liver, AE2 coprecipitated with GAPDH. ELISA and glutathione S-transferase (GST) pull-down assays using GST-tagged C-terminal AE1 fusion protein confirmed that the interaction is direct; fluorescence titration revealed saturable binding kinetics with Kd 2.3±0.2 μM. Further GST precipitation assays demonstrated that the D902EY residues in the D902EYDE motif located within the C terminus of AE1 are important for GAPDH binding. In vitro GAPDH activity was unaffected by C-terminal AE1 binding, unlike in erythrocytes. Also, differently from red cell N-terminal binding, GAPDH-AE1 C-terminal binding was not disrupted by phosphorylation of AE1 in kidney AE1-expressing MDCK cells. Importantly, small interfering RNA knockdown of GAPDH in these cells resulted in significant intracellular retention of AE1, with a concomitant reduction in AE1 at the cell membrane. These results indicate differences between kidney and erythrocyte AE1/GAPDH behavior and show that in the kidney, GAPDH is required for kidney AE1 to achieve stable basolateral residency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980406"}
{"pmid": "20980407", "title": "Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney.", "content": "Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney. Hyperhomocysteinemia, a condition of elevated blood homocysteine (Hcy) levels, is a metabolic disease. It is a common clinical finding in patients with chronic kidney diseases and occurs almost uniformly in patients with end-stage renal disease. Hyperhomocysteinemia is also a risk factor for cardiovascular disease. Our recent studies indicate that hyperhomocysteinemia can lead to renal injury by inducing oxidative stress. Oxidative stress is one of the important mechanisms contributing to Hcy-induced tissue injury. Folic acid supplementation is regarded as a promising approach for prevention and treatment of cardiovascular disease associated with hyperhomocysteinemia due to its Hcy-lowering effect. However, its effect on the kidney is not clear. The aim of this study was to examine the effect of folic acid supplementation on Hcy-induced superoxide anion production via nicotinamide adenine dinucleotide phosphate (NADPH) oxidase in the kidney during hyperhomocysteinemia. Hyperhomocysteinemia was induced in male Sprague-Dawley rats fed a high-methionine diet for 12 wk with or without folic acid supplementation. A group of rats fed a regular diet was used as control. There was a significant increase in levels of superoxide anions and lipid peroxides in kidneys isolated from hyperhomocysteinemic rats. Activation of NADPH oxidase was responsible for hyperhomocysteinemia-induced oxidative stress in the kidney. Folic acid supplementation effectively antagonized hyperhomocysteinemia-induced oxidative stress via its Hcy-lowering and Hcy-independent effect. In vitro study also showed that 5-methyltetrahydrofolate, an active form of folate, effectively reduced Hcy-induced superoxide anion production via NADPH oxidase. Xanthine oxidase activity was increased and superoxide dismutase (SOD) activity was decreased in the kidney of hyperhomocysteinemic rats, which might also contribute to an elevation of superoxide anion level in the kidney. Folic acid supplementation attenuated xanthine oxidase activity and restored SOD activity in the kidney of hyperhomocysteinemic rats. These results suggest that folic acid supplementation may offer renal protective effect against oxidative stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980407"}
{"pmid": "20980405", "title": "Basal lamina secreted by MDCK cells has size- and charge-selective properties.", "content": "Basal lamina secreted by MDCK cells has size- and charge-selective properties. The role electrical charge plays in determining glomerular permeability to macromolecules remains unclear. If the glomerular basement membrane (GBM) has any significant role in permselectivity, physical principles would suggest a negatively charged GBM would reject similarly charged more than neutral species. However, recent in vivo studies with negative and neutral glomerular probes showed the opposite. Whether this observation is due to unique characteristics of the probes used or is a general physiological phenomenon remains to be seen. The goal of this study was to use the basement membrane deposited by Madin-Darby canine kidney epithelial cells as a simple model of a biologically derived, negatively charged filter to evaluate size- and charge-based sieving properties. Fluorescein isothiocyanate-labeled carboxymethylated Ficoll 400 (FITC-CM Ficoll 400) and amino-4-methyl-coumarin-labeled Ficoll 400 (AMC Ficoll 400) were used as negatively charged and neutral tracer molecules, respectively, during pressure-driven filtration. Streaming potential measurement indicated the presence of fixed, negative charge in the basal lamina. The sieving coefficient for neutral Ficoll 400 decreased by ∼0.0013 for each 1-Å increment in solute radius, compared with a decrease of 0.0023 per Å for the anionic Ficoll 400. In this system, molecular charge played a significant role in determining the sieving characteristics of the membrane, pointing to solute charge as a potential contributor to GBM permselectivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980405"}
{"pmid": "20980408", "title": "Is caveolin involved in normal proximal tubule function? Presence in model PT systems but absence in situ.", "content": "Is caveolin involved in normal proximal tubule function? Presence in model PT systems but absence in situ. Kidney proximal tubule (PT) cells are specialized for the uptake and transport of ions, solutes, peptides, and proteins. These functions are often regulated by hormones that signal at the cell surface and are internalized by clathrin-mediated endocytosis. However, the caveolin/caveolae pathway has also been implicated in normal PT function, often based on data from isolated PTs or PT cells in culture. Although we reported previously that caveolae and caveolin 1 are not detectable in PTs in vivo, reports of caveolin expression and function in PT cells appear periodically in the literature. Therefore, we reexamined caveolin expression in PTs in vivo, in isolated \"purified\" PTs following collagenase digestion, and in cultured PT cells. Caveolin 1 and 2 protein, mRNA, or immunofluorescence was undetectable in PTs in vivo, but PT cell cultures expressed caveolin 1 and/or 2. Furthermore, caveolin 1 and 2 mRNAs were detected in isolated PTs along with the endothelial markers CD31 and ICAM1. In contrast, no caveolin or endothelial marker mRNAs were detectable in samples isolated from snap-frozen kidneys by laser cut microdissection, which eliminates contamination by other cell types. We conclude 1) caveolin 1 and 2 are not normally expressed by PT cells in situ, 2) caveolin expression is \"activated\" in cultured PT cells, 3) contamination with non-PT, caveolin-expressing cells is a potential source of caveolin 1 and 2 that must be taken into account when isolated PTs are used in studies to correlate expression of these proteins with PT function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980408"}
{"pmid": "20980410", "title": "Connecting chronic and recurrent stress to vascular dysfunction: no relaxed role for the renin-angiotensin system.", "content": "Connecting chronic and recurrent stress to vascular dysfunction: no relaxed role for the renin-angiotensin system. The renin-angiotensin system (RAS) is classically considered to be a protective system for volume balance and is activated during states of volume depletion. Interestingly, one of the major pathways activating the system is the sympathetic nervous system, also the primary mediator of the acute stress response. When one further examines the cells mediating the immune site of the response, which is primarily an inflammatory response leading to defense at a locally injured area, these cells all express the ANG II type 1 receptor (AGTR1). Scattered throughout the literature are reports indicating that acute and chronic stress can activate renin and increase plasma levels of components of the RAS. Moreover, there are reports describing that ANG II can modulate the distribution and function of immune cells. Since the inflammatory response is also implicated to be central in the initiation and progression of vascular damage, we propose in this review that recurrent acute stress and chronic stress can induce a state with inflammation, due to ANG II-mediated activation of inflammatory cells, specifically monocytes and lymphocytes. Such a proposal would explain a lot of the observations regarding RAS components in inflammatory cells. Despite its attractiveness, substantial research in this area would be required to substantiate this hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980410"}
{"pmid": "20980404", "title": "Role of canonical Wnt signaling/ß-catenin via Dermo1 in cranial dermal cell development.", "content": "Role of canonical Wnt signaling/ß-catenin via Dermo1 in cranial dermal cell development. Cranial dermis develops from cephalic mesoderm and neural crest cells, but what signal(s) specifies the dermal lineage is unclear. Using genetic tools to fate map and manipulate a cranial mesenchymal progenitor population in the supraorbital region, we show that the dermal progenitor cells beneath the surface ectoderm process canonical Wnt signaling at the time of specification. We show that Wnt signaling/β-catenin is absolutely required and sufficient for Dermo1 expression and dermal cell identity in the cranium. The absence of the Wnt signaling cue leads to formation of cartilage in craniofacial and ventral trunk regions at the expense of dermal and bone lineages. Dermo1 can be a direct transcription target and may mediate the functional role of Wnt signaling in dermal precursors. This study reveals a lineage-specific role of canonical Wnt signaling/β-catenin in promoting dermal cell fate in distinct precursor populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980404"}
{"pmid": "20980409", "title": "Chronic vasodilation produces plasma volume expansion and hemodilution in rats: consequences of decreased effective arterial blood volume.", "content": "Chronic vasodilation produces plasma volume expansion and hemodilution in rats: consequences of decreased effective arterial blood volume. Plasma volume (PV) expansion is required for optimal pregnancy outcomes; however, the mechanisms responsible for sodium and water retention in pregnancy remain undefined. This study was designed to test the \"arterial underfill hypothesis\" of pregnancy which proposes that an enlarged vascular compartment (due to systemic vasodilation and shunting of blood to the placenta) results in renal sodium and water retention and PV expansion. We produced chronic vasodilation by 14 days administration of nifedipine (NIF; 10 mg·kg(-1)·day(-1)) or sodium nitrite (NaNO2; 70 mg·kg(-1)·day(-1)) to normal, nonpregnant female Sprague-Dawley rats. Mean arterial pressure, monitored by telemetry, was reduced by both NIF and NaNO2 but was unchanged in control rats. At day 14, vasodilator treatment lowered hematocrit and increased PV (determined by Evans blue dye dilution). Plasma osmolarity (Posm), sodium (PNa), and total protein concentrations all fell. These responses resemble the responses to normal pregnancy with hemodilution, marked PV expansion, and decreased Posm and PNa. Our previous work indicates a role of increased inner medullary phosphodiesterase-5 (PDE5) in the sodium retention of pregnancy. Here, we found that inner medullary PDE5A mRNA and protein expression were increased by both NIF and NaNO2 treatment vs. control; however, neither renal cortical nor aortic PDE5 expression was changed by vasodilator treatment. We suggest that a primary, persistent vasodilation drives increased inner medullary PDE5 expression which facilitates continual renal Na retention causing \"refilling\" of the vasculature and volume expansion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980409"}
{"pmid": "20980411", "title": "High glucose causes dysfunction of the human glomerular endothelial glycocalyx.", "content": "High glucose causes dysfunction of the human glomerular endothelial glycocalyx. The endothelial glycocalyx is a gel-like layer which covers the luminal side of blood vessels. The glomerular endothelial cell (GEnC) glycocalyx is composed of proteoglycan core proteins, glycosaminoglycan (GAG) chains, and sialoglycoproteins and has been shown to contribute to the selective sieving action of the glomerular capillary wall. Damage to the systemic endothelial glycocalyx has recently been associated with the onset of albuminuria in diabetics. In this study, we analyze the effects of high glucose on the biochemical structure of the GEnC glycocalyx and quantify functional changes in its protein-restrictive action. We used conditionally immortalized human GEnC. Proteoglycans were analyzed by Western blotting and indirect immunofluorescence. Biosynthesis of GAG was analyzed by radiolabeling and quantified by anion exchange chromatography. FITC-albumin was used to analyze macromolecular passage across GEnC monolayers using an established in vitro model. We observed a marked reduction in the biosynthesis of GAG by the GEnC under high-glucose conditions. Further analysis confirmed specific reduction in heparan sulfate GAG. Expression of proteoglycan core proteins remained unchanged. There was also a significant increase in the passage of albumin across GEnC monolayers under high-glucose conditions without affecting interendothelial junctions. These results reproduce changes in GEnC barrier properties caused by enzymatic removal of heparan sulfate from the GEnC glycocalyx. They provide direct evidence of high glucose-induced alterations in the GEnC glycocalyx and demonstrate changes to its function as a protein-restrictive layer, thus implicating glycocalyx damage in the pathogenesis of proteinuria in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980411"}
{"pmid": "20980412", "title": "Impact of positive family history and genetic risk variants on the incidence of diabetes: the Finnish Diabetes Prevention Study.", "content": "Impact of positive family history and genetic risk variants on the incidence of diabetes: the Finnish Diabetes Prevention Study. We aimed to investigate the influence of positive family history (FH+) of diabetes and 19 known genetic risk loci on the effectiveness of lifestyle changes and their predictive value on the incidence of type 2 diabetes in the Finnish Diabetes Prevention Study (DPS). A total of 522 subjects with impaired glucose tolerance (IGT) were randomized into the control (n = 257) and intervention (n = 265) groups. The mean follow-up was 6.2 years (median 7 years), and the lifestyle intervention, aimed at weight reduction, healthy diet, and increased physical activity, lasted for 4 years (range 1-6 years). An oral glucose tolerance test (OGTT) and assessment of basic clinical variables were performed annually. The effect of intervention on the incidence of diabetes was almost similar in subjects with FH+ compared with subjects with a negative family history (FH-) of diabetes during the entire follow-up. In the Cox model, including FH, genetic risk SNPs, and randomization group, and adjusted for the effects of age, sex, BMI, and study center, only lifestyle intervention had a significant effect (hazard ratio 0.55, 95% CI 0.41-0.75, P < 0.001) on the incidence of diabetes. Further analyses showed that in addition to the baseline glucose and insulin values, 1-year changes in 2-h glucose and 2-h insulin achieved by lifestyle intervention had a significant effect on the incidence of diabetes. These results emphasize the effectiveness of lifestyle intervention in reducing the risk of diabetes in high-risk individuals independently of genetic or familial risk of type 2 diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980412"}
{"pmid": "20980413", "title": "Untreated type 2 diabetes and its complications are associated with subcortical infarctions.", "content": "Untreated type 2 diabetes and its complications are associated with subcortical infarctions. To investigate the association of type 2 diabetes with subcortical infarctions. We investigated this association in subjects with type 2 diabetes (case subjects; n = 93) and without type 2 diabetes (control subjects; n = 186), matched by age, sex, and years of education. Participants were a subset of the Mayo Clinic Study of Aging (median age 79 years) who had undergone magnetic resonance imaging. The frequency of subcortical infarctions was 39% in case subjects and 29% in control subjects (odds ratio 1.59 [95% CI 0.91-2.75]). The association was stronger in case subjects without treatment (2.60 [1.11-6.08]) and in case subjects with diabetes-related complications (1.96 [1.02-3.74]) compared with control subjects. These findings suggest that untreated type 2 diabetes and type 2 diabetes with complications are associated with subcortical infarctions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980413"}
{"pmid": "20980414", "title": "Low HDL cholesterol, metformin use, and cancer risk in type 2 diabetes: the Hong Kong Diabetes Registry.", "content": "Low HDL cholesterol, metformin use, and cancer risk in type 2 diabetes: the Hong Kong Diabetes Registry. The AMP-activated protein kinase (AMPK) pathway is a master regulator in energy metabolism and may be related to cancer. In type 2 diabetes, low HDL cholesterol predicts cancer, whereas metformin usage is associated with reduced cancer risk. Both metformin and apolipoprotein A1 activate the AMPK signaling pathway. We hypothesize that the anticancer effects of metformin may be particularly evident in type 2 diabetic patients with low HDL cholesterol. In a consecutive cohort of 2,658 Chinese type 2 diabetic patients enrolled in the study between 1996 and 2005, who were free of cancer and not using metformin at enrollment or during 2.5 years before enrollment and who were followed until 2005, we measured biological interactions for cancer risk using relative excess risk as a result of interaction (RERI) and attributable proportion (AP) as a result of interaction. A statistically significant RERI >0 or AP >0 indicates biological interaction. During 13,808 person-years of follow-up (median 5.51 years), 129 patients developed cancer. HDL cholesterol <1.0 mmol/L was associated with increased cancer risk among those who did not use metformin, but the association was not significant among those who did. Use of metformin was associated with reduced cancer risk in patients with HDL cholesterol <1.0 mmol/L and, to a lesser extent, in patients with HDL cholesterol ≥ 1.0 mmol/L. HDL cholesterol <1.0 mmol/L plus nonuse of metformin was associated with an adjusted hazard ratio of 5.75 (95% CI 3.03-10.90) compared with HDL cholesterol ≥ 1.0 mmol/L plus use of metformin, with a significant interaction (AP 0.44 [95% CI 0.11-0.78]). The anticancer effect of metformin was most evident in type 2 diabetic patients with low HDL cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980414"}
{"pmid": "20980415", "title": "Metformin and cancer occurrence in insulin-treated type 2 diabetic patients.", "content": "Metformin and cancer occurrence in insulin-treated type 2 diabetic patients. Metformin is associated with reduced cancer-related morbidity and mortality. The aim of this study was to assess the effect of metformin on cancer incidence in a consecutive series of insulin-treated patients. A nested case-control study was performed in a cohort of 1,340 patients by sampling, for each case subject, age-, sex-, and BMI-matched control subjects from the same cohort. During a median follow-up of 75.9 months, 112 case patients who developed incident cancer and were compared with 370 control subjects. A significantly lower proportion of case subjects were exposed to metformin and sulfonylureas. After adjustment for comorbidity, glargine, and total insulin doses, exposure to metformin, but not to sulfonylureas, was associated with reduced incidence of cancer (odds ratio 0.46 [95% CI 0.25-0.85], P = 0.014 and 0.75 [0.39-1.45], P = 0.40, respectively). The reduction of cancer risk could be a further relevant reason for maintaining use of metformin in insulin-treated patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980415"}
{"pmid": "20980417", "title": "Nonmyeloablative allogeneic stem cell transplantation for nasopharyngeal carcinoma.", "content": "Nonmyeloablative allogeneic stem cell transplantation for nasopharyngeal carcinoma. We present a case of a patient with metastatic nasopharyngeal carcinoma who failed two lines of palliative combination chemotherapy and was treated with allogeneic nonmyeloablative stem cell transplantation (NST). This patient achieved a durable tumor response, dramatic relief of his symptoms, and elimination of tumor in his bone marrow-an effect likely achieved via a graft-versus-tumor response. Although NST has been explored previously in solid tumors, such as renal cell carcinoma and breast cancer, it has not been widely explored in nasopharyngeal carcinoma. We also present data from a flow cytometric immune analysis and cytokine enzyme-linked immunosorbent assay analysis in the pre- and post-NST period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980417"}
{"pmid": "20980416", "title": "Effect of letrozole on plasma lipids, triglycerides, and estradiol in postmenopausal women with metastatic breast cancer.", "content": "Effect of letrozole on plasma lipids, triglycerides, and estradiol in postmenopausal women with metastatic breast cancer. The aromatase inhibitor letrozole effectively treats breast cancer by decreasing estrogen levels in postmenopausal women. The aim of this prospective study was to evaluate the effect of letrozole on plasma lipids, triglyceride lipase (TGL), and estradiol levels in women with metastatic breast cancer (MBC). Fifty-two postmenopausal women with MBC received letrozole, 2.5 mg/day. Blood samples for assessment of plasma levels of total cholesterol (TC), low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol, TGL, and estradiol were taken at baseline and after 3, 6, and 12 months of treatment. A nonsignificant increase was found in TC and HDL cholesterol levels after 3 months, which returned to baseline levels after 6 months (p = .794 and p = .444, respectively). LDL cholesterol increased nonsignificantly after 6 months and returned to baseline thereafter (p = .886). The mean estradiol level was suppressed from 44 pmol/l before treatment to <18 pmol/l after 6 months (p = .014). No difference was found in the estradiol suppression rate whether baseline levels were >40 or <40 pmol/l. Letrozole has a safe effect on the lipid and TGL profiles of postmenopausal women with MBC. Estradiol levels were maximally suppressed within 6 months of treatment. The increased levels of TC during treatment were reversible and returned to normal levels after 3 months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980416"}
{"pmid": "20980419", "title": "Incidence of type 1 diabetes has doubled in Rome and the Lazio region in the 0- to 14-year age-group: a 6-year prospective study (2004-2009).", "content": "Incidence of type 1 diabetes has doubled in Rome and the Lazio region in the 0- to 14-year age-group: a 6-year prospective study (2004-2009).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980419"}
{"pmid": "20980418", "title": "Cardiovascular disease and glycemic treatment.", "content": "Cardiovascular disease and glycemic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980418"}
{"pmid": "20980420", "title": "Type 1 diabetes caused by interferon alpha-2alpha in polycythemia vera therapy.", "content": "Type 1 diabetes caused by interferon alpha-2alpha in polycythemia vera therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980420"}
{"pmid": "20980421", "title": "Altered sleep patterns in adolescents with type 1 diabetes: implications for insulin regimen.", "content": "Altered sleep patterns in adolescents with type 1 diabetes: implications for insulin regimen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980421"}
{"pmid": "20980422", "title": "Prevalence of allergic rhinitis is lower in subjects with higher levels of fasting plasma glucose.", "content": "Prevalence of allergic rhinitis is lower in subjects with higher levels of fasting plasma glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980422"}
{"pmid": "20980423", "title": "Multiuse 10-g monofilament contamination.", "content": "Multiuse 10-g monofilament contamination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980423"}
{"pmid": "20980424", "title": "Gestational diabetes mellitus: simplifying the international association of diabetes and pregnancy diagnostic algorithm using fasting plasma glucose: comment on agarwal, dhatt, and shah.", "content": "Gestational diabetes mellitus: simplifying the international association of diabetes and pregnancy diagnostic algorithm using fasting plasma glucose: comment on agarwal, dhatt, and shah.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980424"}
{"pmid": "20980426", "title": "Supervised walking groups to increase physical activity in type 2 diabetic patients.", "content": "Supervised walking groups to increase physical activity in type 2 diabetic patients. To evaluate the impact of an exercise program organized into supervised walking groups in subjects with type 2 diabetes. Fifty-nine diabetic subjects were randomized to a control group receiving standard lifestyle recommendations or an intervention group assigned to three supervised walking sessions per week and counseling. Changes in metabolic features, weight, 6-min walk test, prescription of antidiabetic medications, and overall physical activity were assessed. Functional capacity and overall physical activity were higher in the intervention group, whereas metabolic changes were not different between groups after 4 months. However, in subjects who attended at least 50% of scheduled walking sessions, changes in A1C and fasting glucose were greater than in control subjects. Discontinuation or reduction of antidiabetic drugs occurred in 33% of these patients versus 5% of control subjects (P<0.05). Supervised walking may be beneficial in diabetic subjects, but metabolic improvement requires adequate compliance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980426"}
{"pmid": "20980427", "title": "Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): a 12-month, randomized, controlled, double-masked, multicenter phase II study.", "content": "Safety and efficacy of ranibizumab in diabetic macular edema (RESOLVE Study): a 12-month, randomized, controlled, double-masked, multicenter phase II study. The expression of vascular endothelial growth factor (VEGF) is elevated in diabetic macular edema (DME). Ranibizumab binds to and inhibits multiple VEGF variants. We investigated the safety and efficacy of ranibizumab in DME involving the foveal center. This was a 12-month, multicenter, sham-controlled, double-masked study with eyes (age>18 years, type 1 or 2 diabetes, central retinal thickness [CRT]≥300 μm, and best corrected visual acuity [BCVA] of 73-39 ETDRS letters [Early Treatment Diabetic Retinopathy Study]) randomly assigned to intravitreal ranibizumab (0.3 or 0.5 mg; n=51 each) or sham (n=49). The treatment schedule comprised three monthly injections, after which treatment could be stopped/reinitiated with an opportunity for rescue laser photocoagulation (protocol-defined criteria). After month 1, dose-doubling was permitted (protocol-defined criteria, injection volume increased from 0.05 to 0.1 ml and remained at 0.1 ml thereafter). Efficacy (BCVA and CRT) and safety were compared between pooled ranibizumab and sham arms using the full analysis set (n=151, patients receiving≥1 injection). At month 12, mean±SD BCVA improved from baseline by 10.3±9.1 letters with ranibizumab and declined by 1.4±14.2 letters with sham (P<0.0001). Mean CRT reduction was 194.2±135.1 μm with ranibizumab and 48.4±153.4 μm with sham (P<0.0001). Gain of ≥10 letters BCVA from baseline occurred in 60.8% of ranibizumab and 18.4% of sham eyes (P<0.0001). Safety data were consistent with previous studies of intravitreal ranibizumab. Ranibizumab is effective in improving BCVA and is well tolerated in DME. Future clinical trials are required to confirm its long-term efficacy and safety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980427"}
{"pmid": "20980428", "title": "Targeting the pathophysiology of diabetic macular edema.", "content": "Targeting the pathophysiology of diabetic macular edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980428"}
{"pmid": "20980429", "title": "Menstrual irregularity and cardiovascular mortality.", "content": "Menstrual irregularity and cardiovascular mortality. Polycystic ovary syndrome, the most common cause of irregular menstrual cycles, is associated with an adverse cardiovascular risk profile. However, there are limited prospective studies confirming the link between polycystic ovary syndrome and cardiovascular mortality. We studied 15,005 pregnant women recruited from the Kaiser Foundation Health Plan in California between 1959 and 1966. The menstrual cycle pattern was assessed at baseline according to self-report, physician report, and medical record abstraction. Participants were matched to California Vital Status files annually until 2007 to identify deaths due to overall cardiovascular disease (CVD) and subsets of coronary heart disease (CHD) and cerebrovascular disease based on International Classification of Diseases codes. Cox proportional hazards models were used to estimate the association between irregular cycles and cardiovascular mortality. Missing covariate data were multiply imputated using standard methods. During 456,298.5 person-years of follow-up, there were 666 CVD deaths, including 301 CHD deaths and 149 cerebrovascular deaths. Compared with women with regular cycles, women with irregular cycles had an increased risk for CHD mortality [age adjusted hazards ratio (HR) 1.42, 95% confidence interval (CI) 1.03-1.94]; however, the association was not statistically significant after adjustment for body mass index (adjusted HR 1.35, 95% CI 0.98-1.85). There was a nonsignificant increase in CVD mortality (age adjusted HR 1.21, 95% CI 0.97-1.52) but not cerebrovascular mortality (age adjusted HR 0.85, 95% CI 0.49-1.47). In this large prospective cohort of pregnant women, we found an increase in age-adjusted risk for CHD mortality in women with irregular menstrual cycles. This risk was attenuated after adjustment for body mass index.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980429"}
{"pmid": "20980430", "title": "Polymorphism in vitamin D-binding protein as a genetic risk factor in the pathogenesis of endometriosis.", "content": "Polymorphism in vitamin D-binding protein as a genetic risk factor in the pathogenesis of endometriosis. Previous studies have implicated a deficiency in the inflammatory response in women who develop endometriosis. The specific immunological deficits have not been completely elucidated. Our objective was to identify differences in protein expression in serum that might shed light on the pathophysiology of endometriosis. This cross-sectional study of women undergoing laparoscopy between 2003 and 2005 took place at a university medical center. Patients included consenting women age 18-49 yr undergoing surgery for pain and/or infertility or elective tubal ligation. Women with acute or chronic medical conditions were excluded. Blood was collected preoperatively. Proteomic analysis of serum was done using two-dimensional difference gel electrophoresis. We found 25 protein spots with a significant difference in abundance between women with endometriosis and controls, including acute-phase proteins and complement components. The abundance of vitamin D-binding protein was higher in all endometriosis pools by a factor of approximately 3 compared with the control pool (P < 0.02). Analysis of specific allele products using nano-scale liquid chromatography-electrospray ionization-mass spectrometry indicated that it was the GC*2 allele product that was in greater concentration in serum pools, as well as in single validation samples, in women with endometriosis (P = 0.006). In contrast to the GC*1 allele product, which is readily converted to a potent macrophage factor (Gc protein-derived macrophage-activating factor), the GC*2 allele product undergoes practically no such conversion. We speculate that the inability to sufficiently activate macrophages' phagocytotic function in those carrying the GC*2 polymorphism (more prevalent in endometriosis) may allow endometriotic tissues to implant in the peritoneal cavity. Future studies evaluating specific vitamin D-binding protein polymorphisms as a risk factor for endometriosis in larger populations of women are warranted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980430"}
{"pmid": "20980431", "title": "Association of 25(OH)D and PTH with metabolic syndrome and its traditional and nontraditional components.", "content": "Association of 25(OH)D and PTH with metabolic syndrome and its traditional and nontraditional components. Emerging evidence suggests that 25-hydroxy vitamin D [25(OH)D] and PTH may play a role in the etiology of the metabolic syndrome (MetS). However, evidence to date is limited and inconsistent, and few studies have examined associations with nontraditional MetS components. The objective of the study was to examine the association of vitamin D and PTH with MetS and its traditional and nontraditional components in a large multiethnic sample. In this cross-sectional study, we examined 654 participants from London and Toronto, Ontario, Canada, aged 30 yr and older with risk factors for type 2 diabetes. Presence of MetS and its traditional and nontraditional components was measured. Approximately 43% of the study participants were classified as having MetS. Higher 25(OH)D was significantly associated with a reduced presence of MetS after adjustment for age, sex, season, ethnicity, supplement use, physical activity, and PTH (odds ratio 0.76, 95% confidence interval 0.62-0.93). PTH was not associated with the presence of MetS after multivariate adjustment. Multivariate linear regression analyses indicated significant adjusted inverse associations of 25(OH)D with waist circumference, triglyceride level, fasting insulin, and alanine transaminase (P < 0.041). Elevated PTH was positively associated with waist circumference and high-density lipoprotein cholesterol (P < 0.04). Other associations between PTH and MetS components were attenuated after adjustment for adiposity. Serum 25(OH)D, but not PTH, was significantly associated with MetS as well as a number of MetS components after multivariate adjustment. These results suggest that low 25(OH)D may play a role in the etiology of the MetS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980431"}
{"pmid": "20980432", "title": "Normal cortisol response to high-dose synacthen and insulin tolerance test in children and adults with Prader-Willi syndrome.", "content": "Normal cortisol response to high-dose synacthen and insulin tolerance test in children and adults with Prader-Willi syndrome. Prader-Willi syndrome (PWS) is a genetic disease associated with hypogonadism and partial GH insufficiency, possibly explained in part by a hypothalamic dysfunction. Partial insufficiency of the hypothalamic-pituitary-adrenal (HPA) axis has recently been suggested. The objective of the study was to further explore the HPA axis in PWS by use of routine tests. Nonselected PWS patients were examined with a standard high-dose synacthen test or the insulin tolerance test (ITT). A random serum (s) cortisol was measured in case of acute illness. The study was conducted at university hospitals in Denmark and Sweden. Sixty-five PWS patients with a confirmed genetic diagnosis participated in the study. A s-cortisol value above 500 nmol/liter as well as an increase of 250 nmol/liter or greater was considered a normal response. Fifty-seven PWS patients (median age 22 yr, total range 0.5-48 yr) were examined with the high-dose synacthen test. The median s-cortisol at the time of 30 min was 699 (474-1578) nmol/liter. Only one patient had a s-cortisol level below 500 nmol/liter but an increase of 359 nmol/liter. This patient subsequently showed a normal ITT response. Two patients had increases less than 250 nmol/liter but a time of 30-min s-cortisol values of 600 nmol/liter or greater. These three patients were interpreted as normal responders. Eight patients [aged 26 (16-36) yr] examined with the ITT had a median peak s-cortisol of 668 (502-822) nmol/liter. Four children admitted for acute illnesses had s-cortisol values ranging from 680 to 1372 nmol/liter. In this PWS cohort, the function of the HPA axis was normal, suggesting that clinically significant adrenal insufficiency in PWS is rare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980432"}
{"pmid": "20980433", "title": "Downregulation of c-MYC protein levels contributes to cancer cell survival under dual deficiency of oxygen and glucose.", "content": "Downregulation of c-MYC protein levels contributes to cancer cell survival under dual deficiency of oxygen and glucose. The c-MYC protein participates in energy-consuming processes such as proliferation and ribosome biosynthesis, and its expression is often dysregulated in human cancers. Cancer cells distant from blood vessels in solid tumors are in short supply of oxygen and nutrition yet can adapt to the microenvironment and survive under metabolic stress. The role and regulation of c-MYC protein in the tumor microenvironment of limited energy sources are poorly understood. Here, we show that c-MYC protein levels in cancer cells are strikingly reduced in the area distant from the blood vessels in vivo and also under oxygen- and glucose-deprived conditions in vitro. The rapid reduction of c-MYC protein levels requires low levels of both oxygen and glucose, and under these conditions, downregulation is mainly achieved by enhanced degradation. Suppression of c-MYC protein levels by small hairpin RNA decreases the necrotic cell death induced by oxygen and glucose deprivation. Thus, the environmental milieu regulates c-MYC protein levels, and downregulation of c-MYC might be a strategy for cancer cells to survive under conditions of limited energy sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980433"}
{"pmid": "20980434", "title": "p38 kinase is crucial for osteopontin-induced furin expression that supports cervical cancer progression.", "content": "p38 kinase is crucial for osteopontin-induced furin expression that supports cervical cancer progression. p38 kinases activated by growth factors, hormones, and environmental stresses exert diverse functions in regulating normal and malignant cell pathophysiology. Enhanced levels of activated p38 isoforms have been linked with poor prognosis in breast cancer, although the mechanistic basis for this association is poorly understood. In this study, we report that p38 activation in cervical cancer cells is driven by osteopontin (OPN), an extracellular matrix-associated cytokine that drives invasive progression. OPN regulates CD44-mediated p38 phosphorylation that induces NF-κB activation and NF-κB-dependent expression of furin, an extracellular protease implicated in human papilloma virus (HPV) processing that enhances cervical cancer cell motility. OPN induces CD44-mediated MKK3/6 phosphorylation which in turn phosphorylates p38 in these cells. OPN-induced furin expression and cell motility was impeded by blockades to MKK3/6, p38α/β or NF-κB signaling. In a mouse xenograft model of human cervical cancer, tumor growth was enhanced by OPN overexpression and blocked by short hairpin RNA (shRNA)-mediated OPN silencing. Furin overexpression similarly augmented tumor growth in the model, whereas blocking MKK3/6, p38, or furin reduced OPN-induced cervical tumor growth. Analysis of clinical specimens revealed that enhanced expression of OPN, phosphorylated NF-κB, p65, and furin correlated with cervical cancer progression, further strengthening the in vitro and in vivo results. In summary, our findings offer a proof of concept for targeting OPN and its downstream p38 signaling as a novel therapeutic strategy to manage cervical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980434"}
{"pmid": "20980435", "title": "Mechanisms of progesterone receptor inhibition of inflammatory responses in cellular models of breast cancer.", "content": "Mechanisms of progesterone receptor inhibition of inflammatory responses in cellular models of breast cancer. Both pro- and antimitogenic activities have been ascribed to progesterone receptor (PR) agonists and antagonists in breast cancer cells; however, the transcriptional responses that underlie these paradoxical functions are not apparent. Using nontransformed, normal human mammary epithelial cells engineered to express PR and standard microarray technology, we defined 2370 genes that were significantly regulated by the PR agonist R5020. Gene ontology (GO) analysis revealed that GO terms involved in inflammation and nuclear factor-κB (NF-κB) signaling were among the most significantly regulated. Interestingly, on those NF-κB responsive genes that were inhibited by agonist-activated PR, antagonists either 1) mimicked the actions of agonists or 2) reversed the inhibitory actions of agonists. This difference in pharmacological response could be attributed to the fact that although agonist- and antagonist-activated PR is recruited to NF-κB-responsive promoters, the physical presence of PR tethered to the promoter of some genes is sufficient for transcriptional inhibition, whereas on others, an agonist-activated PR conformation is required for inhibition of NF-κB signaling. Importantly, the actions of PR on the latter class of genes were reversed by an activation function-2-inhibiting, LXXLL-containing peptide. Consideration of the relative activities of these distinct antiinflammatory pathways in breast cancer may be instructive with respect to the likely therapeutic activity of PR agonists or antagonists in the treatment of breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980435"}
{"pmid": "20980438", "title": "Differences in the insulin tolerance test in patients with brain damage depending on posture.", "content": "Differences in the insulin tolerance test in patients with brain damage depending on posture. The insulin tolerance test (ITT) is the gold standard for the diagnosis of GH deficiency (GHD) and hypocortisolism. As hypopituitarism is a common disorder after traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH), the test is increasingly used in patients with pre-existing brain damage. A cross-sectional, observational study. Fifty-six patients (41 TBI and 15 SAH) were tested with the ITT (0.15 IE/kg body weight, mean glucose 33 mg/dl). In 38 patients, the test was performed in a supine position; the other 18 patients were in a sitting position during the ITT. Hypocortisolism and GHD were more often diagnosed in a supine than in a sitting position (hypocortisolism: 55.3% supine versus 0% sitting, P<0.0001; GHD: 42.1% supine versus 11.1% sitting, P=0.03). Patients in a sitting position suffered more often from symptoms such as tachycardia (61.1% sitting versus 15.8% supine, P=0.001), trembling (22.2 vs 7.9%, NS), and sweating (66.7 vs 28.9%, P=0.007). There were no significant differences between the groups in drowsiness (72.2% sitting versus 65.8% supine, NS), dizziness (44.4 vs 44.7%, NS), and fatigue (33.3 vs 15.8%, NS). Because of somnolence, the hypoglycemic state could only be stopped with i.v. administration of glucose in 25 supine patients (66%). In contrast, none of the 18 patients (0%) tested in a sitting position got somnolent or was in need of i.v. application of glucose (P<0.001). In patients with brain injury, posture might affect rates of diagnosing GHD and hypocortisolism and sympathetic symptoms in the ITT. These findings are exploratory and need replication in a standardized setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980438"}
{"pmid": "20980436", "title": "Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas.", "content": "Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas. The six major genes involved in hereditary susceptibility for pheochromocytoma (PCC)/paraganglioma (PGL) (RET, VHL, NF1, SDHB, SDHC, and SDHD) have been recently integrated into the same neuronal apoptotic pathway where mutations in any of these genes lead to cell death. In this model, prolyl hydroxylase 3 (EglN3) abrogation plays a pivotal role, but the molecular mechanisms underlying its inactivation are currently unknown. The aim of the study was to decipher specific alterations associated with the different genetic classes of PCCs/PGLs. With this purpose, 84 genetically characterized tumors were analyzed by means of transcriptional profiling. The analysis revealed a hypoxia-inducible factor (HIF)-related signature common to succinate dehydrogenase (SDH) and von Hippel-Lindau (VHL) tumors, that differentiated them from RET and neurofibromatosis type 1 cases. Both canonical HIF-1α and HIF-2α target genes were overexpressed in the SDH/VHL cluster, suggesting that a global HIF deregulation accounts for this common profile. Nevertheless, when we compared VHL tumors with SDHB cases, which often exhibit a malignant behavior, we found that HIF-1α target genes showed a predominant activation in the VHL PCCs. Expression data from 67 HIF target genes was sufficient to cluster SDHB and VHL tumors into two different groups, demonstrating different pseudo-hypoxic signatures. In addition, VHL-mutated tumors showed an unexpected overexpression of EglN3 mRNA that did not lead to significantly different EglN3 protein levels. These findings pave the way for more specific therapeutic approaches for malignant PCCs/PGLs management based on the patient's genetic alteration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980436"}
{"pmid": "20980437", "title": "CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation.", "content": "CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation. Previously we determined that S81 is the highest stoichiometric phosphorylation on the androgen receptor (AR) in response to hormone. To explore the role of this phosphorylation on growth, we stably expressed wild-type and S81A mutant AR in LHS and LAPC4 cells. The cells with increased wild-type AR expression grow faster compared with parental cells and S81A mutant-expressing cells, indicating that loss of S81 phosphorylation limits cell growth. To explore how S81 regulates cell growth, we tested whether S81 phosphorylation regulates AR transcriptional activity. LHS cells stably expressing wild-type and S81A mutant AR showed differences in the regulation of endogenous AR target genes, suggesting that S81 phosphorylation regulates promoter selectivity. We next sought to identify the S81 kinase using ion trap mass spectrometry to analyze AR-associated proteins in immunoprecipitates from cells. We observed cyclin-dependent kinase (CDK)9 association with the AR. CDK9 phosphorylates the AR on S81 in vitro. Phosphorylation is specific to S81 because CDK9 did not phosphorylate the AR on other serine phosphorylation sites. Overexpression of CDK9 with its cognate cyclin, Cyclin T, increased S81 phosphorylation levels in cells. Small interfering RNA knockdown of CDK9 protein levels decreased hormone-induced S81 phosphorylation. Additionally, treatment of LNCaP cells with the CDK9 inhibitors, 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole and Flavopiridol, reduced S81 phosphorylation further, suggesting that CDK9 regulates S81 phosphorylation. Pharmacological inhibition of CDK9 also resulted in decreased AR transcription in LNCaP cells. Collectively these results suggest that CDK9 phosphorylation of AR S81 is an important step in regulating AR transcriptional activity and prostate cancer cell growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980437"}
{"pmid": "20980439", "title": "DNA damage response.", "content": "DNA damage response. Structural changes to DNA severely affect its functions, such as replication and transcription, and play a major role in age-related diseases and cancer. A complicated and entangled network of DNA damage response (DDR) mechanisms, including multiple DNA repair pathways, damage tolerance processes, and cell-cycle checkpoints safeguard genomic integrity. Like transcription and replication, DDR is a chromatin-associated process that is generally tightly controlled in time and space. As DNA damage can occur at any time on any genomic location, a specialized spatio-temporal orchestration of this defense apparatus is required.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980439"}
{"pmid": "20980440", "title": "Bacterial small RNA regulators: versatile roles and rapidly evolving variations.", "content": "Bacterial small RNA regulators: versatile roles and rapidly evolving variations. Small RNA regulators (sRNAs) have been identified in a wide range of bacteria and found to play critical regulatory roles in many processes. The major families of sRNAs include true antisense RNAs, synthesized from the strand complementary to the mRNA they regulate, sRNAs that also act by pairing but have limited complementarity with their targets, and sRNAs that regulate proteins by binding to and affecting protein activity. The sRNAs with limited complementarity are akin to eukaryotic microRNAs in their ability to modulate the activity and stability of multiple mRNAs. In many bacterial species, the RNA chaperone Hfq is required to promote pairing between these sRNAs and their target mRNAs. Understanding the evolution of regulatory sRNAs remains a challenge; sRNA genes show evidence of duplication and horizontal transfer but also could be evolved from tRNAs, mRNAs or random transcription.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980440"}
{"pmid": "20980443", "title": "Transcription factor E2F-associated phosphoprotein (EAPP), RAM2/CDCA7L/JPO2 (R1), and simian virus 40 promoter factor 1 (Sp1) cooperatively regulate glucocorticoid activation of monoamine oxidase B.", "content": "Transcription factor E2F-associated phosphoprotein (EAPP), RAM2/CDCA7L/JPO2 (R1), and simian virus 40 promoter factor 1 (Sp1) cooperatively regulate glucocorticoid activation of monoamine oxidase B. Glucocorticoid steroid hormones play important roles in many neurophysiological processes such as responses to stress, behavioral adaption, and mood. One mechanism by which glucocorticoids exert functions in the brain is via the modulation of neurotransmission systems. Glucocorticoids are capable of inducing the activities of monoamine oxidases (MAOs), which degrade monoamine neurotransmitters including serotonin, norepinephrine, phenylethylamine, and dopamine. However, the molecular mechanisms for such induction are not yet fully understood. Here, we report that dexamethasone, a synthetic glucocorticoid hormone, stimulates MAO B (an isoform of MAOs) promoter and catalytic activities via both the fourth glucocorticoid response element (GRE) and simian virus 40 promoter factor 1 (Sp1) binding sites in MAO B promoter. Electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation analysis demonstrated that glucocorticoid receptor binds to the fourth GRE in vitro and in vivo. Using Sp1-binding motifs as bait in a yeast one-hybrid system, we identified two novel transcriptional repressors of MAO B, E2F-associated phosphoprotein (EAPP) and R1 (RAM2/CDCA7L/JPO2), that down-regulate MAO B via MAO B core promoter, which contains Sp1 sites. EMSA suggested that EAPP and R1 competed with Sp1 for binding to the Sp1 site in vitro. Moreover, EAPP and R1 reduced Sp1-activated glucocorticoid activation of MAO B promoter. In response to dexamethasone, lower occupancy by EAPP and R1 and higher occupancy by Sp1 were shown at the natural MAO B core promoter. Together, this study uncovers for the first time the molecular mechanisms for glucocorticoid activation of MAO B gene and provides new insights into the hormonal regulation of MAO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980443"}
{"pmid": "20980445", "title": "The prevention of schizophrenia.", "content": "The prevention of schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980445"}
{"pmid": "20980442", "title": "Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression.", "content": "Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression. Cells of the mammary gland are in intimate contact with other cells and with the extracellular matrix (ECM), both of which provide not only a biochemical context, but a mechanical context as well. Cell-mediated contraction allows cells to sense the stiffness of their microenvironment, and respond with appropriate mechanosignaling events that regulate gene expression and differentiation. ECM composition and organization are tightly regulated throughout development of the mammary gland, resulting in corresponding regulation of the mechanical environment and proper tissue architecture. Mechanical regulation is also at play during breast carcinoma progression, as changes in ECM deposition, composition, and organization accompany breast carcinoma. These changes result in stiffer matrices that activate mechanosignaling pathways and thereby induce cell proliferation, facilitate local tumor cell invasion, and promote progression. Thus, understanding the role of forces in the mammary gland is crucial to understanding both normal developmental and pathological processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980442"}
{"pmid": "20980446", "title": "Delayed elimination of SN-38 in cancer patients with severe renal failure.", "content": "Delayed elimination of SN-38 in cancer patients with severe renal failure. This prospective study is designed to examine the effects of severe renal failure on the pharmacokinetics of irinotecan. The pharmacokinetics of irinotecan, 7-ethyl-10-hydroxycamptothecin (SN-38), and SN-38 glucuronide (SN-38G) in three cancer patients with severe renal failure [creatinine clearance (Ccr) ≤ 20 ml/min] who were undergoing dialysis and received 100 mg/m(2) irinotecan as monotherapy were prospectively compared with those in five cancer patients with normal renal function (Ccr ≥ 60 ml/min). To ensure that the subjects had similar genetic backgrounds of UDP-glucuronosyltransferase (UGT) 1A1, patients with UGT1A1*1/*1, *1/*6, or *1/*28 were enrolled. The estimated terminal elimination rate constant of SN-38 in patients undergoing dialysis was approximately one tenth of that in patients with normal renal function (P = 0.025). Approximately 50% of SN-38 was dialyzed with a 2.1-m(2) dialysis membrane, whereas 27% was dialyzed with a 1.5-m(2) membrane. Our results showed that the elimination of SN-38 was significantly delayed in patients with severe renal failure compared with patients with normal renal function. We demonstrated that SN-38 was partly dialyzed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980446"}
{"pmid": "20980448", "title": "Efficacy of radiofrequency ablation in the treatment of small functional adrenal neoplasms.", "content": "Efficacy of radiofrequency ablation in the treatment of small functional adrenal neoplasms. To evaluate the use of radiofrequency (RF) ablation as a primary treatment for symptomatic primary functional adrenal neoplasms and determine the efficacy of treatment with use of clinical and biochemical follow-up. After obtaining institutional review board approval, the authors retrospectively evaluated images and medical records from 13 consecutive patients with symptomatic functional adrenal neoplasms (<3.2 cm in diameter) who underwent RF ablation during a 7-year period. There were six men and seven women with a mean age of 54.1 years (range, 42-71 years). Cross-sectional images, findings from clinical examination, and adrenal biochemical markers were available for all patients. Ten of the 13 patients (77%) had an aldosteronoma and one patient each had a cortisol-secreting tumor, testosterone-secreting tumor, and pheochromocytoma. RF ablation was performed by two radiologists using an internally cooled electrode and a pulsed technique according to manufacturer's specifications. Clinical and laboratory follow-up was performed for all patients. Three patients underwent imaging follow-up for other reasons. All patients demonstrated resolution of abnormal biochemical markers after ablation (mean biochemical follow-up, 21.2 months). In addition, all patients experienced resolution of clinical symptoms or syndromes, including hypertension and hypokalemia (in patients with aldosteronoma), Cushing syndrome (in the patient with cortisol-secreting tumor), virilizing symptoms (in the patient with testosterone-secreting tumor), and hypertension (in the patient with pheochromocytoma). For the patients with aldosteronoma, improvements in hypertension management were noted. The mean blood pressure before ablation was 149/90 mm Hg with a mean (±standard deviation) of 3.1 ± 0.6 blood pressure medications, and this decreased to 122/77 mm Hg at a mean of 2.8 months after ablation with 1.3 ± 0.9 medications (P < .001) and 124/75 mm Hg at a mean of 41.4 months. There were two minor complications: one small pneumothorax and one limited hemothorax, neither of which required overnight admission. There were two episodes of transient self-remitting procedural hypertension-one in a patient with aldosteronoma and one in the patient with a cortisol-secreting tumor; however, none of these patients required further therapy during overnight observation. RF ablation may be an effective, minimally invasive method for treating small functional primary adrenal tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980448"}
{"pmid": "20980447", "title": "Advanced hepatocellular carcinoma: early evaluation of response to bevacizumab therapy at dynamic contrast-enhanced US with quantification--preliminary results.", "content": "Advanced hepatocellular carcinoma: early evaluation of response to bevacizumab therapy at dynamic contrast-enhanced US with quantification--preliminary results. To investigate whether there is any correlation between standard efficacy endpoints-specifically, tumor response, progression-free survival, and overall survival-and tumor perfusion parameters measured by using dynamic contrast material-enhanced ultrasonography (US) in patients with advanced hepatocellular carcinoma (HCC) treated with bevacizumab. The institutional review board approved the study, and all patients provided written informed consent before their enrollment. Between June 3, 2005, and September 28, 2007, 42 patients (33 men, nine women; median age, 62 years; age range, 23-84 years) participated in this phase II study of single-agent bevacizumab treatment. Tumor response (based on RECIST [response evaluation criteria in solid tumors]) at 2 months was assessed in 37 patients, and progression-free survival and overall survival were assessed in all 42 patients. Dynamic contrast-enhanced US (ie, dynamic US) was performed before treatment (day 0); on days 3, 7, 14, and 60 after treatment; and every 2 months thereafter. Tumor perfusion parameters were estimated quantitatively from contrast material uptake curves constructed from raw linear data. The changes in dynamic US functional parameters between day 0 and the later time points were compared between treatment responders and nonresponders by using nonparametric tests. Given multiple comparisons, P < .001 indicated significance. The percentage decrease in several dynamic US parameters between day 0 and day 3 showed trends toward correlation with (a) tumor response in terms of total area under the time-intensity curve (AUC) (P = .02), AUC during wash in (P = .04), AUC during washout (P = .02), and time to peak intensity (P = .03); (b) progression-free survival in terms of time to peak intensity (P = .028); and (c) overall survival in terms of AUC (P = .002) and AUC during washout (P = .003). Dynamic US can be used to quantify dynamic changes in tumor vascularity as early as 3 days after bevacizumab administration in patients with HCC. These early changes in tumor perfusion may be predictive of tumor response at 2 months, progression-free survival, and overall survival, and they may be potential surrogate measures of the effectiveness of antiangiogenic therapy in patients with HCC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980447"}
{"pmid": "20980441", "title": "IP(3) receptors: toward understanding their activation.", "content": "IP(3) receptors: toward understanding their activation. Inositol 1,4,5-trisphosphate receptors (IP(3)R) and their relatives, ryanodine receptors, are the channels that most often mediate Ca(2+) release from intracellular stores. Their regulation by Ca(2+) allows them also to propagate cytosolic Ca(2+) signals regeneratively. This brief review addresses the structural basis of IP(3)R activation by IP(3) and Ca(2+). IP(3) initiates IP(3)R activation by promoting Ca(2+) binding to a stimulatory Ca(2+)-binding site, the identity of which is unresolved. We suggest that interactions of critical phosphate groups in IP(3) with opposite sides of the clam-like IP(3)-binding core cause it to close and propagate a conformational change toward the pore via the adjacent N-terminal suppressor domain. The pore, assembled from the last pair of transmembrane domains and the intervening pore loop from each of the four IP(3)R subunits, forms a structure in which a luminal selectivity filter and a gate at the cytosolic end of the pore control cation fluxes through the IP(3)R.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980441"}
{"pmid": "20980450", "title": "Acute pancreatitis: imaging utilization practices in an urban teaching hospital--analysis of trends with assessment of independent predictors in correlation with patient outcomes.", "content": "Acute pancreatitis: imaging utilization practices in an urban teaching hospital--analysis of trends with assessment of independent predictors in correlation with patient outcomes. To evaluate imaging utilization trends in patients with acute pancreatitis (AP) and to assess independent predictors of radiology usage in relation to patient outcomes. Institutional review board approval was obtained for this HIPAA-compliant study; written informed consent was waived. AP-related radiologic studies in 252 patients admitted for AP between June 2005 and December 2007 were collected during and for a 1-year period after hospitalization. Clinical data were collected from patients' medical records, while imaging data were obtained from the radiology information system. Linear regression models were used to investigate predictors and time trends of imaging utilization, after adjustment for confounders. Patient outcomes, measured by using mortality, intensive care unit admission, need for surgical intervention, organ failure, and persistent systemic inflammatory response syndrome, were evaluated by using logistic regression. Mean utilization was 9.9 radiologic studies per patient (95% confidence interval: 7.5, 12.3), with relative value unit (RVU) of 7.8 (95% confidence interval: 6.3, 9.4). Utilization was highest on day 0, declining rapidly by day 4; 53% of imaging occurred during initial hospitalization. Chest radiography (38%) and abdominal computed tomography (CT) (17%) were the most commonly performed studies. Patients with longer hospital stay (P = .001), higher Acute Physiology and Chronic Health Evaluation II score (P = .0012), higher pain levels (P = .003), drug-induced AP (P = .002), and prior episodes of AP (P < .001) underwent significantly more radiologic studies. After adjustment for confounders, a 2.5-fold increase in the use of high-cost (CT and magnetic resonance imaging) examinations and a 1.4-fold increase in RVUs per case-mix-adjusted admissions (P < .05) were observed during the 2.5-year study period. This increased use was not associated with improvement in patient outcomes. AP severity explained substantial variation in imaging utilization. After case-mix adjustment for severity and other patient level factors, there was still increasing use over the course of time without notable improvement in patient outcomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980450"}
{"pmid": "20980444", "title": "Neural correlates of olfactory learning: Critical role of centrifugal neuromodulation.", "content": "Neural correlates of olfactory learning: Critical role of centrifugal neuromodulation. The mammalian olfactory system is well established for its remarkable capability of undergoing experience-dependent plasticity. Although this process involves changes at multiple stages throughout the central olfactory pathway, even the early stages of processing, such as the olfactory bulb and piriform cortex, can display a high degree of plasticity. As in other sensory systems, this plasticity can be controlled by centrifugal inputs from brain regions known to be involved in attention and learning processes. Specifically, both the bulb and cortex receive heavy inputs from cholinergic, noradrenergic, and serotonergic modulatory systems. These neuromodulators are shown to have profound effects on both odor processing and odor memory by acting on both inhibitory local interneurons and output neurons in both regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980444"}
{"pmid": "20980451", "title": "Snapshot inversion recovery: an optimized single-shot T1-weighted inversion-recovery sequence for improved fetal brain anatomic delineation.", "content": "Snapshot inversion recovery: an optimized single-shot T1-weighted inversion-recovery sequence for improved fetal brain anatomic delineation. To prospectively evaluate the clinical effectiveness of snapshot inversion recovery (SNAPIR), which is a dedicated optimized inversion-recovery-prepared single-shot fast spin-echo T1-weighted sequence, in the delineation of normal fetal brain anatomy compared with that of the currently used T1-weighted gradient-echo protocol, which often yields images of poor quality due to motion artifacts and inadequate contrast. This study was approved by the hospital research ethics committee, and informed written consent was obtained from all patients. Forty-one fetuses were examined at 19-37 weeks gestation (mean, 29 weeks gestation) by using both the standard T1-weighted protocol and the optimized T1-weighted SNAPIR protocol with a 1.5-T imager. Two independent blinded observers performed qualitative analysis, evaluating overall diagnostic quality, detailed anatomic delineation, and severity of motion artifacts. Quantitative analysis comprised calculation of contrast ratios (CRs) for the cortical gray matter, subplate, white matter, and cerebrospinal fluid. The Wilcoxon signed rank test was used to compare image rating scores, the paired t test was used to compare CRs, and κ statistics were used to test interobserver agreement. Both overall diagnostic quality (P < .001) and detailed anatomic delineation (P < .001) were enhanced with SNAPIR compared with the standard T1-weighted acquisition. Also, motion artifacts were less severe (P = .008) and less extensive (P < .001) with SNAPIR. Corresponding CRs were increased with SNAPIR in seven of eight examined regions. SNAPIR is a promising robust alternative to the current T1-weighted acquisitions; its role in the detection of disease requires further study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980451"}
{"pmid": "20980449", "title": "Renal arteries: isotropic, high-spatial-resolution, unenhanced MR angiography with three-dimensional radial phase contrast.", "content": "Renal arteries: isotropic, high-spatial-resolution, unenhanced MR angiography with three-dimensional radial phase contrast. To prospectively compare a new three-dimensional (3D) radial phase-contrast magnetic resonance (MR) angiographic method with contrast material-enhanced MR angiography for anatomic assessment of the renal arteries. An institutional review board approved this prospective HIPAA-compliant study. Informed consent was obtained. Twenty-seven subjects (mean age, 52.6 years ± 20.5 [standard deviation]) were imaged with respiratory-gated phase-contrast vastly undersampled isotropic projection reconstruction (VIPR) prior to contrast-enhanced MR angiographic acquisition with a 3.0-T clinical system. The imaging duration for phase-contrast VIPR was 10 minutes and provided magnitude and complex difference (\"angiographic\") images with 3D volumetric (320 mm) coverage and isotropic high spatial resolution (1.25 mm(3)). Quantitative analysis consisted of comparing vessel diameters between the two techniques. Qualitative assessment included evaluation of the phase-contrast VIPR and contrast-enhanced MR angiographic techniques for artifacts, noise, and image quality. Bland-Altman analysis was used for comparison of quantitative measurements, and the Wilcoxon signed rank test was used for comparison of qualitative scores. Phase-contrast VIPR images were successfully acquired in all subjects. The vessel diameters measured with phase-contrast VIPR were slightly greater than those measured with contrast-enhanced MR angiography (mean bias = 0.09 mm). Differences in mean artifact, quality scores for the proximal renal arteries, and overall image quality scores between phase-contrast VIPR and contrast-enhanced MR angiographic techniques were not statistically significant (P = .31 and .29, .27 and .39, and .43 and .69 for readers 1 and 2, respectively). The quality scores for the segmental renal arteries were higher for phase-contrast VIPR than for contrast-enhanced MR angiography (P < .05). Although the noise scores were higher with phase-contrast VIPR than with contrast-enhanced MR angiography and were statistically significant (P < .05), the presence of noise did not interfere with the ability to interpret the images. Isotropic, high-spatial-resolution, unenhanced MR angiography of the renal arteries is feasible with 3D radial undersampling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980449"}
{"pmid": "20980453", "title": "Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant.", "content": "Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant. Variation in the transcription factor 7-like 2 (TCF7L2) locus is associated with type 2 diabetes across multiple ethnicities. The aim of this study was to elucidate which variant in TCF7L2 confers diabetes susceptibility in African Americans. Through the evaluation of tagging single nucleotide polymorphisms (SNPs), type 2 diabetes susceptibility was limited to a 4.3-kb interval, which contains the YRI (African) linkage disequilibrium (LD) block containing rs7903146. To better define the relationship between type 2 diabetes risk and genetic variation we resequenced this 4.3-kb region in 96 African American DNAs. Thirty-three novel and 13 known SNPs were identified: 20 with minor allele frequencies (MAF) >0.05 and 12 with MAF >0.10. These polymorphisms and the previously identified DG10S478 microsatellite were evaluated in African American type 2 diabetic cases (n = 1,033) and controls (n = 1,106). Variants identified from direct sequencing and databases were genotyped or imputed. Fifteen SNPs showed association with type 2 diabetes (P < 0.05) with rs7903146 being the most significant (P = 6.32 × 10(-6)). Results of imputation, haplotype, and conditional analysis of SNPs were consistent with rs7903146 being the trait-defining SNP. Analysis of the DG10S478 microsatellite, which is outside the 4.3-kb LD block, revealed consistent association of risk allele 8 with type 2 diabetes (odds ratio [OR] = 1.33; P = 0.022) as reported in European populations; however, allele 16 (MAF = 0.016 cases and 0.032 controls) was strongly associated with reduced risk (OR = 0.39; P = 5.02 × 10(-5)) in contrast with previous studies. In African Americans, these observations suggest that rs7903146 is the trait-defining polymorphism associated with type 2 diabetes risk. Collectively, these results support ethnic differences in type 2 diabetes associations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980453"}
{"pmid": "20980452", "title": "Urinary 8-hydroxy-2'-deoxyguanosine as a biomarker of oxidative DNA damage induced by ambient pollution in the Normative Aging Study.", "content": "Urinary 8-hydroxy-2'-deoxyguanosine as a biomarker of oxidative DNA damage induced by ambient pollution in the Normative Aging Study. Studies show that exposure to air pollution damages human health, but the mechanisms are not fully understood. One suggested pathway is via oxidative stress. This study examines associations between exposure to air pollution and oxidative DNA damage, as indicated by urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) concentrations in ageing participants during 2006-2008. We fit linear regression models to examine associations between air pollutants and 8-OHdG adjusting for potential confounders. 8-OHdG was significantly associated with ambient particulate matter ≤2.5 μm in aerodynamic diameter (PM(2.5)), nitrogen dioxide (NO(2)), maximal 1 h ozone (O(3)), sulphate (SO(4)(2-)) and organic carbon (OC), but not with black carbon (BC), carbon monoxide (CO), the number of particles (PN) or elemental carbon (EC). Effects were more apparent with multi-week averages of exposures. Per IQR increases in 21-day averages of PM(2.5), PN, BC, EC, OC, CO, SO(4)(2-), NO(2) and maximal 1 h O(3) were associated with 30.8% (95% CI 9.3% to 52.2%), -13.1% (95% CI -41.7% to 15.5%), 3.0% (95% CI -19.8% to 25.8%), 5.3% (95% CI -23.6% to 34.2%), 24.4% (95% CI 1.8% to 47.1%), -2.0% (95% CI -12.4% to 8.3%), 29.8% (95% CI 6.3% to 53.3%), 32.2% (95% CI 7.4% to 56.9%) and 47.7% (95% CI 3.6% to 91.7%) changes in 8-OHdG, respectively. This study suggests that ageing participants experienced an increased risk of developing oxidative DNA injury after exposure to secondary, but not primary, ambient pollutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980452"}
{"pmid": "20980454", "title": "Congenital hyperinsulinism and glucose hypersensitivity in homozygous and heterozygous carriers of Kir6.2 (KCNJ11) mutation V290M mutation: K(ATP) channel inactivation mechanism and clinical management.", "content": "Congenital hyperinsulinism and glucose hypersensitivity in homozygous and heterozygous carriers of Kir6.2 (KCNJ11) mutation V290M mutation: K(ATP) channel inactivation mechanism and clinical management. The ATP-sensitive K(+) channel (K(ATP)) controls insulin secretion from the islet. Gain- or loss-of-function mutations in channel subunits underlie human neonatal diabetes and congenital hyperinsulinism (HI), respectively. In this study, we sought to identify the mechanistic basis of K(ATP)-induced HI in two probands and to characterize the clinical course. We analyzed HI in two probands and characterized the course of clinical treatment in each, as well as properties of mutant K(ATP) channels expressed in COSm6 cells using Rb efflux and patch-clamp methods. We identified mutation V290M in the pore-forming Kir6.2 subunit in each proband. In vitro expression in COSm6 cells supports the mutation resulting in an inactivating phenotype, which leads to significantly reduced activity in intact cells when expressed homomerically, and to a lesser extent when expressed heteromerically with wild-type subunits. In one heterozygous proband, a fluoro-DOPA scan revealed a causal focal lesion, indicating uniparental disomy with loss of heterozygosity. In a second family, the proband, homozygous for the mutation, was diagnosed with severe diazoxide-unresponsive hypersinsulinism at 2 weeks of age. The patient continues to be treated successfully with octreotide and amlodipine. The parents and a male sibling are heterozygous carriers without overt clinical HI. Interestingly, both the mother and the sibling exhibit evidence of abnormally enhanced glucose tolerance. V290M results in inactivating K(ATP) channels that underlie HI. Homozygous individuals may be managed medically, without pancreatectomy. Heterozygous carriers also show evidence of enhanced glucose sensitivity, consistent with incomplete loss of K(ATP) channel activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980454"}
{"pmid": "20980455", "title": "High connectivity between reduced cortical thickness and disrupted white matter tracts in long-standing type 1 diabetes.", "content": "High connectivity between reduced cortical thickness and disrupted white matter tracts in long-standing type 1 diabetes. Previous studies have observed disruptions in brain white and gray matter structure in individuals with type 1 diabetes, and these structural differences have been associated with neurocognitive testing deficiencies. This study investigated the relationship between cerebral cortical thickness reductions and white matter microstructural integrity loss in a group of patients with type 1 diabetes and in healthy control subjects using diffusion tensor imaging (DTI). Twenty-five subjects with type 1 diabetes for at least 15 years and 25 age- and sex-matched control subjects underwent structural T1 and proton-density and DTI on a 3.0 Tesla scanner. Fractional anisotropy measurements were made on major cerebral white matter tracts, and DTI tractography was performed to identify cortical regions with high connectivity to these tracts. Posterior white matter tracts with reduced fractional anisotropy (optic radiations, posterior corona radiata, and the splenium region of the corpus callosum) were found to have high connectivity with a number of posterior cortical regions, including the cuneus, precuneus, fusiform, and posterior parietal cortical regions. A significant reduction in cortical thickness in the diabetic group was observed in the regions with high connectivity to the optic radiations and posterior corona radiata tracts (P < 0.05). The direct relationship between white and gray matter structural pathology has not been previously demonstrated in subjects with long-standing type 1 diabetes. The relationship between posterior white matter microstructural integrity disruption and lower cortical thickness demonstrated using a novel DTI connectivity technique suggests a common or interrelated pathophysiological mechanism in type 1 diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980455"}
{"pmid": "20980456", "title": "Levels of oxidized LDL and advanced glycation end products-modified LDL in circulating immune complexes are strongly associated with increased levels of carotid intima-media thickness and its progression in type 1 diabetes.", "content": "Levels of oxidized LDL and advanced glycation end products-modified LDL in circulating immune complexes are strongly associated with increased levels of carotid intima-media thickness and its progression in type 1 diabetes. High cholesterol levels in circulating immune complexes (IC), surrogate markers of modified LDL, are associated with increased carotid intima-media thickness (IMT) and cardiovascular events in type 1 diabetes. Different modifications of LDL are involved in IC formation, but which of these are predictive of vascular events is not known. Therefore, we measured oxidized LDL (oxLDL), advanced glycation end products-modified LDL (AGE-LDL), and malondialdehyde-modified LDL (MDA-LDL) in IC and determined their relationship with increased carotid IMT and compared the strength of the association with that observed with conventional risk factors. Levels of oxLDL, AGE-LDL, and MDA-LDL were measured in circulating IC isolated from sera of 479 patients of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort, collected at baseline. Internal and common carotid IMT were measured 8 and 14 years later by DCCT/EDIC. OxLDL, AGE-LDL, and MDA-LDL levels in circulating IC were significantly correlated with diabetes duration, BMI, and lipid and blood pressure, but not with age. Multivariate logistic regression models indicated that individuals in the highest versus lowest quartile of oxLDL and AGE-LDL in IC had a 6.11-fold [confidence interval (CI) 2.51-14.8] and a 6.4-fold (CI 2.53-16.2) increase in the odds of having high carotid IMT, respectively, after adjusting for conventional risk factors. Parallel analyses resulted in odds ratios of 2.62 (CI 1.24, 5.55) for LDL-C, 1.45 (CI 0.69, 3.03) for diastolic blood pressure, and 2.33 (CI 1.09, 4.99) for A1C. OxLDL and AGE-LDL in circulating IC were significantly associated with progression and increased levels of carotid IMT in type 1 diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980456"}
{"pmid": "20980458", "title": "mt-Nd2(a) Modifies resistance against autoimmune type 1 diabetes in NOD mice at the level of the pancreatic β-cell.", "content": "mt-Nd2(a) Modifies resistance against autoimmune type 1 diabetes in NOD mice at the level of the pancreatic β-cell. To investigate whether a single nucleotide polymorphism (SNP) in the mitochondrial gene for NADH dehydrogenase 2 (mt-Nd2) can modulate susceptibility to type 1 diabetes in NOD mice. NOD/ShiLtJ mice conplastic for the alloxan resistant (ALR)/Lt-derived mt-Nd2(a) allele (NOD.mt(ALR)) were created and compared with standard NOD (carrying the mt-Nd2(c) allele) for susceptibility to spontaneous autoimmune diabetes, or to diabetes elicited by reciprocal adoptive splenic leukocyte transfers, as well as by adoptive transfer of diabetogenic T-cell clones. β-Cell lines derived from either the NOD (NIT-1) or the NOD.mt(ALR) (NIT-4) were also created to compare their susceptibility to cytolysis by diabetogenic CD8(+) T-cells in vitro. NOD mice differing at this single SNP developed spontaneous or adoptively transferred diabetes at comparable rates and percentages. However, conplastic mice with the mt-Nd2(a) allele exhibited resistance to transfer of diabetes by the CD4(+) T-cell clone BDC 2.5 as well as the CD8(+) AI4 T-cell clones from T-cell receptor transgenic animals. NIT-4 cells with mt-Nd2(a) were also more resistant to AI4-mediated destruction in vitro than NIT-1 cells. Conplastic introduction into NOD mice of a variant mt-Nd2 allele alone was not sufficient to prevent spontaneous autoimmune diabetes. Subtle nonhematopoietic type 1 diabetes resistance was observed during adoptive transfer experiments with T-cell clones. This study confirms that genetic polymorphisms in mitochondria can modulate β-cell sensitivity to autoimmune T-cell effectors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980458"}
{"pmid": "20980457", "title": "The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential.", "content": "The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential. Although Smad3 has been considered as a downstream mediator of transforming growth factor-β (TGF-β) signaling in diabetes complications, the role of Smad7 in diabetes remains largely unclear. The current study tests the hypothesis that Smad7 may play a protective role and has therapeutic potential for diabetic kidney disease. Protective role of Smad7 in diabetic kidney disease was examined in streptozotocin-induced diabetic mice that have Smad7 gene knockout (KO) and in diabetic rats given Smad7 gene transfer using an ultrasound-microbubble-mediated technique. We found that mice deficient for Smad7 developed more severe diabetic kidney injury than wild-type mice as evidenced by a significant increase in microalbuminuria, renal fibrosis (collagen I, IV, and fibronectin), and renal inflammation (interleukin-1β [IL-1β], tumor necrosis factor-α [TNF-α], monocyte chemoattractant protein-1 [MCP-1], intracellular adhesion molecule-1 [ICAM-1], and macrophages). Further studies revealed that enhanced renal fibrosis and inflammation in Smad7 KO mice with diabetes were associated with increased activation of both TGF-β/Smad2/3 and nuclear factor-κB (NF-κB) signaling pathways. To develop a therapeutic potential for diabetic kidney disease, Smad7 gene was transferred into the kidney in diabetic rats by an ultrasound-microbubble-mediated technique. Although overexpression of renal Smad7 had no effect on levels of blood glucose, it significantly attenuated the development of microalbuminuria, TGF-β/Smad3-mediated renal fibrosis such as collagen I and IV and fibronectin accumulation and NF-κB/p65-driven renal inflammation including IL-1β, TNF-α, MCP-1, and ICAM-1 expression and macrophage infiltration in diabetic rats. Smad7 plays a protective role in diabetic renal injury. Overexpression of Smad7 may represent a novel therapy for the diabetic kidney complication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980457"}
{"pmid": "20980459", "title": "Effects of acute hyperglucagonemia on hepatic and intestinal lipoprotein production and clearance in healthy humans.", "content": "Effects of acute hyperglucagonemia on hepatic and intestinal lipoprotein production and clearance in healthy humans. The metabolism of hepatic- and intestinally derived lipoproteins is regulated in a complex fashion by nutrients, hormones, and neurologic and other factors. Recent studies in animal models suggest an important role for glucagon acting via the glucagon receptor in regulating hepatic triglyceride (TG) secretion. Here we examined the direct effects of glucagon on regulation of hepatic and intestinal lipoprotein metabolism in humans. Eight healthy men underwent two studies each, in random order, 4-6 weeks apart in which de novo lipogenesis, kinetics of larger VLDL1 TG, and kinetics of VLDL1 and smaller VLDL2 apolipoprotein (apo)B100 and B48 were studied using established stable isotope enrichment methods. Subjects were studied in the constant fed state under conditions of a pancreatic clamp (with infusion of somatostatin, insulin, and growth hormone) at either basal glucagon (BG study, 64.5 ± 2.1 pg/mL) or hyperglucagonemia (high glucagon [HG] study, 183.2 ± 5.1 pg/mL). There were no significant differences in plasma concentration of VLDL1 or VLDL2 TG, apoB100 or apoB48 between BG and HG studies. There was, however, lower (P < 0.05) VLDL1 apoB100 fractional catabolic rate (-39%) and production rate (-30%) in HG versus BG, but no difference in de novo lipogenesis or TG turnover, and glucagon had no effect on intestinal (B48-containing) lipoprotein metabolism. Glucagon acutely regulates hepatic but not intestinal lipoprotein particle metabolism in humans both by decreasing hepatic lipoprotein particle production as well as by inhibiting particle clearance, with no net effect on particle concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980459"}
{"pmid": "20980460", "title": "Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes.", "content": "Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes. To determine the role of hepatocyte growth factor (HGF)/c-Met on β-cell survival in diabetogenic conditions in vivo and in response to cytokines in vitro. We generated pancreas-specific c-Met-null (PancMet KO) mice and characterized their response to diabetes induced by multiple low-dose streptozotocin (MLDS) administration. We also analyzed the effect of HGF/c-Met signaling in vitro on cytokine-induced β-cell death in mouse and human islets, specifically examining the role of nuclear factor (NF)-κB. Islets exposed in vitro to cytokines or from MLDS-treated mice displayed significantly increased HGF and c-Met levels, suggesting a potential role for HGF/c-Met in β-cell survival against diabetogenic agents. Adult PancMet KO mice displayed normal glucose and β-cell homeostasis, indicating that pancreatic c-Met loss is not detrimental for β-cell growth and function under basal conditions. However, PancMet KO mice were more susceptible to MLDS-induced diabetes. They displayed higher blood glucose levels, marked hypoinsulinemia, and reduced β-cell mass compared with wild-type littermates. PancMet KO mice showed enhanced intraislet infiltration, islet nitric oxide (NO) and chemokine production, and β-cell apoptosis. c-Met-null β-cells were more sensitive to cytokine-induced cell death in vitro, an effect mediated by NF-κB activation and NO production. Conversely, HGF treatment decreased p65/NF-κB activation and fully protected mouse and, more important, human β-cells against cytokines. These results show that HGF/c-Met is critical for β-cell survival by attenuating NF-κB signaling and suggest that activation of the HGF/c-Met signaling pathway represents a novel strategy for enhancing β-cell protection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980460"}
{"pmid": "20980461", "title": "Molecular mechanisms for activation of the agouti-related protein and stimulation of appetite.", "content": "Molecular mechanisms for activation of the agouti-related protein and stimulation of appetite. The agouti-related protein (Agrp) is a powerful orexigenic peptide, but little is known about its transcriptional regulation. The objective of this study was to determine molecular mechanisms for the activation of hypothalamic Agrp and identify compounds that stimulate appetite. We used promoter analyses methods, hypothalamic cell culture and transfection, immunohistochemistry, luciferase-expressing transgenic mice, in vivo bioluminescence, anitisense RNA, mouse feeding studies, indirect calorimetry, real-time PCR, and Western blots. We found that the Krüppel-like factor 4 (Klf4) is a potent activator of Agrp by binding to a specific CACCC-box in its minimal promoter. We also found that an extract of tarragon, termed PMI-5011, activated hypothalamic Klf4 and Agrp. In vivo, PMI-5011 increased Agrp promoter activity in luciferase-expressing transgenic mice, increased hypothalamic Klf4 and Agrp expression, increased hypothalamic Orexin and melanin-concentrating hormone, increased food intake, reduced circulating insulin and leptin levels, attenuated energy expenditure, and enhanced body weight but only when using a high-fat diet. These data show that Klf4 augmented hypothalamic Agrp by binding to a specific CACCC-box onto its minimal promoter. In addition, the tarragon extract PMI-5011 activated Klf4 and orexigenic neuropeptides and reduced peripheral insulin and leptin levels leading to positive energy balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980461"}
{"pmid": "20980462", "title": "β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency.", "content": "β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. The islet in type 2 diabetes is characterized by β-cell apoptosis, β-cell endoplasmic reticulum stress, and islet amyloid deposits derived from islet amyloid polypeptide (IAPP). Toxic oligomers of IAPP form intracellularly in β-cells in humans with type 2 diabetes, suggesting impaired clearance of misfolded proteins. In this study, we investigated whether human-IAPP (h-IAPP) disrupts the endoplasmic reticulum-associated degradation/ubiquitin/proteasome system. We used pancreatic tissue from humans with and without type 2 diabetes, isolated islets from h-IAPP transgenic rats, isolated human islets, and INS 832/13 cells transduced with adenoviruses expressing either h-IAPP or a comparable expression of rodent-IAPP. Immunofluorescence and Western blotting were used to detect polyubiquitinated proteins and ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) protein levels. Proteasome activity was measured in isolated rat and human islets. UCH-L1 was knocked down by small-interfering RNA in INS 832/13 cells and apoptosis was evaluated. We report accumulation of polyubiquinated proteins and UCH-L1 deficiency in β-cells of humans with type 2 diabetes. These findings were reproduced by expression of oligomeric h-IAPP but not soluble rat-IAPP. Downregulation of UCH-L1 expression and activity to reproduce that caused by h-IAPP in β-cells induced endoplasmic reticulum stress leading to apoptosis. Our results indicate that defective protein degradation in β-cells in type 2 diabetes can, at least in part, be attributed to misfolded h-IAPP leading to UCH-L1 deficiency, which in turn further compromises β-cell viability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980462"}
{"pmid": "20980464", "title": "Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy.", "content": "Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy. Genital ulcer disease (GUD) is associated with increased HIV-1-RNA shedding in antiretroviral therapy (ART)-naive women. The effect of GUD on HIV-1 shedding among ART-treated women is not known. The objective of this study was to test the hypothesis that genital ulcerations increase genital HIV-1-RNA shedding in women receiving ART. Eligible women initiated ART and attended monthly visits with inspection for genital lesions and collection of genital swabs. GUD cases diagnosed after 2 months or more on ART were included for analysis and served as their own controls. HIV-1 RNA was quantitated in specimens collected before, during and after GUD for all cases. The lower limit of quantitation was 100 HIV-1-RNA copies/swab. Using the pre-GUD visit as the reference, the detection of genital HIV-1 RNA before versus during and after GUD episodes was compared. 36 women had GUD episodes after ART initiation. HIV-1 RNA was detected before, during and after GUD in cervical secretions from four (11%), one (3%) and six (17%) women, respectively, and in vaginal secretions from three (8%), four (11%) and four (11%) women, respectively. After adjustment for time on ART, there was no difference in the detection of cervical HIV-1 RNA before versus during GUD (adjusted OR 0.22, 95% CI 0.04 to 1.23). Likewise, GUD did not increase HIV-1 detection in vaginal secretions (adjusted OR 1.32, 95% CI 0.29 to 5.92). GUD did not significantly increase cervical or vaginal HIV-1 shedding. The results suggest that ART maintains its effectiveness for genital HIV-1 suppression despite GUD episodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980464"}
{"pmid": "20980465", "title": "Contraceptive practices, sexual and reproductive health needs of HIV-positive and negative female sex workers in Goa, India.", "content": "Contraceptive practices, sexual and reproductive health needs of HIV-positive and negative female sex workers in Goa, India. In India, female sex workers (FSWs), suffer from high HIV prevalence and abortions. Contraceptive use among general population women is well understood. However, FSWs contraceptives practices and reproductive health needs are under-researched. We investigated contraceptive practices among HIV-positive and negative FSWs in Goa, India and explored its association with socio-demographic and sex work related factors. Cross-sectional study using respondent driven sampling recruited 326 FSWs. They completed an interviewer-administered questionnaire and were screened for STI/HIV. Multivariable logistic regression was used to explore factors associated with sterilisation relative to no contraception. HIV prevalence was high (26%). Of the 59 FSWs planning pregnancy, 33% were HIV-positive and 5-7% had Gonorrhoea, Chlamydia and Trichomonas. 25% and 65% of FSWs screened-positive for Syphilis and Herpes simplex virus type 2 antibodies respectively. Among the 260 FSWs analysed for contraceptive use, 39% did not use contraceptives, and 26% had experienced abortion. Half the FSWs had undergone sterilisation, and only 5% used condoms for contraception. Among HIV-positive FSWs, 45% did not use contraceptives. Sterilisation was independently associated with older age, illiteracy, having an intimate non-paying male partner, having children and financial autonomy. Exposure to National AIDS Control Organisation's HIV-prevention interventions was reported by 34% FSWs and was not significantly associated with contraceptive use (adjusted odds ratio 1.4, 95% CI 0.7 to 2.9). HIV-prevention interventions should promote contraception, especially among young and HIV-positive FSWs. Integrating HIV treatment and care services with HIV-prevention interventions is vital to avert HIV-positive births.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980465"}
{"pmid": "20980463", "title": "Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.", "content": "Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy. The effectiveness of tolerizing immunotherapeutic strategies, such as anti-CD40L or dendritic cells (DCs), is greater when administered to young nonobese diabetic (NOD) mice than at peak insulitis. RelB(lo) DCs, generated in the presence of an nuclear factor-κB inhibitor, induce T-regulatory (Treg) cells and suppress inflammation in a model of rheumatoid arthritis. Interleukin (IL)-1β is overexpressed in humans and mice at risk of type 1 diabetes, dysregulates Treg cells, and accelerates diabetes in NOD mice. We investigated the relationship between IL-1β production and the response to RelB(lo) DCs in the prediabetic period. We injected RelB(lo) DCs subcutaneously into 4- or 14-week-old NOD mice and tracked the incidence of diabetes and effect on Treg cell function. We measured the expression of proinflammatory cytokines by stimulated splenocytes and unstimulated islets from mice of different ages and strains and proliferative and cytokine responses of T effectors to Treg in vitro. Tolerizing RelB(lo) DCs significantly inhibited diabetes progression when administered to 4-week-old but not 14-week-old mice. IL-1β production by NOD splenocytes and mRNA expression by islets increased from 6 to 16 weeks of age when major histocompatibility complex (MHC)-restricted islet antigen presentation to autoreactive T-cells occurred. IL-1 reduced the capacity of Treg cells to suppress effector cells and promoted their conversion to Th17 cells. RelB(lo) DCs exacerbated the IL-1-dependent decline in Treg function and promoted Th17 conversion. IL-1β, generated by islet-autoreactive cells in MHC-susceptible mice, accelerates diabetes by differentiating Th17 at the expense of Treg. Tolerizing DC therapies can regulate islet autoantigen priming and prevent diabetes, but progression past the IL-1β/IL-17 checkpoint signals the need for other strategies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980463"}
{"pmid": "20980466", "title": "Comment on: Yang et al. (2010) Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hong Kong Diabetes Registry. Diabetes;59:1254-1260.", "content": "Comment on: Yang et al. (2010) Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hong Kong Diabetes Registry. Diabetes;59:1254-1260.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980466"}
{"pmid": "20980467", "title": "Comment on: Yang et al. (2010) Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hong Kong Diabetes Registry. Diabetes;59:1254-1260.", "content": "Comment on: Yang et al. (2010) Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hong Kong Diabetes Registry. Diabetes;59:1254-1260.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980467"}
{"pmid": "20980468", "title": "Outstanding Scientific Achievement Award Lecture 2010: deconstructing leptin: from signals to circuits.", "content": "Outstanding Scientific Achievement Award Lecture 2010: deconstructing leptin: from signals to circuits. Martin G. Myers Jr., MD, PhD, received the American Diabetes Association's prestigious 2010 Outstanding Scientific Achievement Award at the Association's 70th Scientific Sessions in Orlando, Florida, on 28 June 2010. The Outstanding Scientific Achievement Award recognizes outstanding scientific achievement in the field of diabetes, taking into consideration independence of thought and originality. Currently the Marilyn H. Vincent Professor of Diabetes Research at the University of Michigan, Ann Arbor, and Associate Professor in internal medicine and in molecular and integrative physiology at the University of Michigan Medical School, Dr. Myers began his impressive track record in diabetes research as a graduate student in the laboratory of Dr. Morris White at the Joslin Diabetes Center/Harvard Medical School. There, Dr. Myers deciphered many of the insulin signaling pathways engaged by insulin receptor substrate proteins. Following his graduation from the Harvard MD-PhD Program in 1997, Dr. Myers was promoted to instructor in medicine at the Joslin Diabetes Center/Harvard Medical School. He began his independent work by building a molecular framework for understanding the mechanisms of leptin signaling, including how individual phosphorylation sites on the leptin receptor recruit distinct signaling molecules. He was promoted to assistant professor at Harvard in 1999. In 2004, Dr. Myers moved to the University of Michigan, where he built upon the molecular framework of leptin signaling to probe the regulation of metabolism by individual leptin signals. Dr. Myers' laboratory revealed the specificity of leptin signals in metabolic control, including the role for leptin-STAT3 signaling in the regulation of energy balance and glucose homeostasis. His group also defined roles for leptin receptor feedback inhibition and hypothalamic mTor signaling in metabolism. Dr. Myers' laboratory has recently developed novel molecular approaches to elucidate the leptin-regulated brain circuits that contribute to metabolic control, enabling the discovery of novel brain systems and their functions. In 1998, Dr. Myers received the American Diabetes Association's Career Development Award for his scientific abilities. Dr. Myers' current support includes the National Institute of Diabetes and Digestive and Kidney Diseases MERIT Award.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980468"}
{"pmid": "20980469", "title": "Health-chair reform: your chair: comfortable but deadly.", "content": "Health-chair reform: your chair: comfortable but deadly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980469"}
{"pmid": "20980470", "title": "Physical activity, sedentary behavior, and health: paradigm paralysis or paradigm shift?", "content": "Physical activity, sedentary behavior, and health: paradigm paralysis or paradigm shift?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980470"}
{"pmid": "20980471", "title": "Final answer: ghrelin can suppress insulin secretion in humans, but is it clinically relevant?", "content": "Final answer: ghrelin can suppress insulin secretion in humans, but is it clinically relevant?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980471"}
{"pmid": "20980472", "title": "Building genetic scores to predict risk of complex diseases in humans: is it possible?", "content": "Building genetic scores to predict risk of complex diseases in humans: is it possible?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980472"}
{"pmid": "20980473", "title": "Diabetes family history: a metabolic storm you should not sit out.", "content": "Diabetes family history: a metabolic storm you should not sit out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980473"}
{"pmid": "20980474", "title": "The welcome resurgence of the α-cell: a pro glucagon commentary.", "content": "The welcome resurgence of the α-cell: a pro glucagon commentary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980474"}
{"pmid": "20980475", "title": "Marine pollution.", "content": "Marine pollution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980475"}
{"pmid": "20980476", "title": "Mass balances and life-cycle inventory for a garden waste windrow composting plant (Aarhus, Denmark).", "content": "Mass balances and life-cycle inventory for a garden waste windrow composting plant (Aarhus, Denmark). A comprehensive life-cycle inventory of all consumptions and emissions of environmental relevance was made for the windrow composting plant treating garden waste in Aarhus (Denmark). The flows of materials and substances within the facility were balanced using the mass-balance model STAN. The overall fuel and electricity use at the facility (3.04 L diesel Mg(-1) wet waste (ww) and 0.2 k Wh Mg(-1) ww) was low whereas the emissions of CH( 4) and N(2)O from the windrows (2.4 ± 0.5 kg CH( 4)-C Mg(-1) ww and 0.06 ± 0.03 kg N(2)O-N Mg(-1) ww) were relatively high compared to data reported in similar studies. The loss of carbon during the 14-month-long composting was 56%. CH(4) made up 2.1% of the C lost. Loss of nitrogen-containing compounds was identified as the most sensible and uncertain parameter and could be relevant for global warming (N(2)O emissions), acidification (NH(3) emissions), and eutrophication (NH(3) and NO(3) emissions). The compost produced had a very low content of heavy metals and was suitable for use in gardens and/or agriculture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980476"}
{"pmid": "20980477", "title": "Nobuhiko Katunuma: an outstanding scientist in the field of proteolysis and warm-hearted 'Kendo Fighter' biochemist.", "content": "Nobuhiko Katunuma: an outstanding scientist in the field of proteolysis and warm-hearted 'Kendo Fighter' biochemist. Professor Nobuhiko Katunuma is well known for his outstanding contribution to the understanding of proteolysis in general and cysteine proteinases and their inhibitors in mammals. In fact, he is a world pioneer in the field. In 1963, he started his highly successful scientific career as a Professor at the Institute for Enzyme Research, the University of Tokushima. During the initial 30 years of his career, he was interested in vitamin B6 metabolism and discovered the acceleration of turnover rates of pyridoxal enzyme in apoprotein formation. After this period, his interest expanded to lysosomal cystein proteinases and their endogenous inhibitors. After determining the crystal structure of human cathepsin B, he generated a series of chemically synthesized specific inhibitors of cathepsins. These inhibitors are currently used throughout the world and some of them have been applied therapeutically in various diseases. During his career and even at present, Professor Katunuma has been studying Biochemistry in Medicine and also practicing to become a 'Kendo sword fencing Fighter'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980477"}
{"pmid": "20980478", "title": "Independent and combined association of physical activity and cardiac disease on mortality risk in the very old.", "content": "Independent and combined association of physical activity and cardiac disease on mortality risk in the very old. This study investigated physical activity as a predictor of all-cause mortality among 75- and 80-year-old people with and without chronic cardiac disease over a 10-year follow-up period. Using the Evergreen Project data, four study groups were formed according to the respondent's self-reported level of physical activity as well as chronic cardiac diseases: active without cardiac disease (control group = ANCD), active with cardiac disease (ACD), sedentary without cardiac disease (SNCD), and sedentary with cardiac disease (SCD). In the analyses, the ACD (HR 1.69, 95% CI 1.02-2.81) and the SNCD (1.76, 1.14-2.73) groups had almost one and a half times greater risk of dying than the control group, while the SCD group had almost three times (2.77, 1.80-4.26) greater risk of dying than the control group. Among the older people with cardiac disease, a physically active lifestyle was associated with lower mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980478"}
{"pmid": "20980479", "title": "Field application of the H9M2e enzyme-linked immunosorbent assay for differentiation of H9N2 avian influenza virus-infected chickens from vaccinated chickens.", "content": "Field application of the H9M2e enzyme-linked immunosorbent assay for differentiation of H9N2 avian influenza virus-infected chickens from vaccinated chickens. Vaccination for control of H9N2 low-pathogenicity avian influenza (LPAI) in chickens began in 2007 in South Korea where the H9N2 virus is prevalent. Recently, an enzyme-linked immunosorbent assay (ELISA) using the extracellular domain of the M2 protein (M2e ELISA) was developed as another strategy to differentiate between vaccinated and infected chickens. Here, an ELISA using the extracellular domain of the M2 protein of H9N2 LPAI virus (H9M2e ELISA) was applied to differentiate infected from vaccinated chickens using the H9N2 LPAI virus M2 peptide. The specificity and sensitivity of the optimized H9M2e ELISA were 96.1% and 83.8% (the absorbance of the sample to the absorbance for the positive control [S/P ratio] ≥ 0.6), respectively, with the cutoff value (S/P ratio = 0.6), and the criterion of avian influenza (AI) infection in a chicken house was established as >20% reactivity of anti-M2e antibody per house with this cutoff value. After infection in naïve chickens and once-vaccinated chickens with a hemagglutination inhibition (HI) assay titer of 9.25 ± 0.75 log(2) units, the sera from infected chickens were confirmed as AI infected when the chickens were 1 week old in both groups, and AI infection lasted for 24 weeks and 9 weeks in naïve and once-vaccinated chickens, respectively, although in twice-vaccinated chickens with a higher HI titer of 11.17 ± 0.37 log(2) units, anti-M2e antibody in infected sera did not reach a level indicating AI infection. In field application, anti-M2e antibody produced in infected chickens after vaccination or in reinfected chickens could be identified as AI infection, although HI test could not distinguish infected from vaccinated sera. These results indicate the utility of H9M2e ELISA as a surveillance tool in control of H9N2 LPAI infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980479"}
{"pmid": "20980480", "title": "Correlation of immune activation during late pregnancy and early postpartum with increases in plasma HIV RNA, CD4/CD8 T cells, and serum activation markers.", "content": "Correlation of immune activation during late pregnancy and early postpartum with increases in plasma HIV RNA, CD4/CD8 T cells, and serum activation markers. A previously observed rise in the plasma viral load postpartum in both treated and untreated HIV-positive women remains unexplained. Virological and immunological markers were evaluated in HIV-negative controls and HIV-positive pregnant women with and without antiretroviral treatment. Plasma HIV RNA, CD4/CD8 T cells, and serum activation markers were sequentially measured during the third trimester, at delivery, and 2 to 8 weeks postpartum in a cohort of HIV-positive pregnant women (n = 96) enrolled in a maternal-fetal HIV transmission study and a control group of HIV-negative pregnant women (n = 28). Mean plasma HIV RNA (P = 0.003) increased from delivery to postpartum, and mean CD4 T cells (P = 0.002) and serum β2-microglobulin (P < 0.0001) increased from the third trimester through postpartum among the HIV-positive women. Mean CD8 T cells increased from the third trimester through postpartum in women receiving zidovudine (ZDV) and in those not treated (P < 0.05) but remained stable in those on highly active antiretroviral therapy (HAART) and the HIV-negative controls. Increases in serum β2-microglobulin were correlated with increases in HIV RNA (P = 0.01). HIV-positive pregnant women showed postpartum increases in plasma HIV RNA, CD4 T cells, and serum β2-microglobulin regardless of the treatment regimen. The rise in CD4 T cells and β2-microglobulin was also observed in HIV-negative pregnant women, suggesting hormonal changes and/or labor-induced cytokines may contribute to immune activation. Immune activation correlated with increased plasma HIV RNA in postpartum women despite treatment, although HAART appeared to blunt the effect. The observed rise in plasma HIV RNA postpartum, which correlated with markers of immune activation, may have implications for enhanced transmission to infants through early breast-feeding and to sexual partners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980480"}
{"pmid": "20980481", "title": "Evaluation of Rickettsia japonica pathogenesis and reservoir potential in dogs by experimental inoculation and epidemiologic survey.", "content": "Evaluation of Rickettsia japonica pathogenesis and reservoir potential in dogs by experimental inoculation and epidemiologic survey. Rickettsia japonica pathogenesis and reservoir potential in dogs were evaluated by both experimental inoculation and epidemiologic survey. In the experimental inoculation study, dogs 1 and 2 were pretreated with an immunosuppressive dose of cyclosporine 14 days before inoculation and became ill after exposure to R. japonica. Dogs exhibited clinical signs, including fever, anorexia, depression, and decreased water consumption, between 36 and 96 h after inoculation, but these signs disappeared spontaneously by 5 days after inoculation. Dogs 3 and 4 were not pretreated with cyclosporine, and no clinical signs were detected in them throughout the 14-day observation period. The control dog was clinically normal and had a normal rectal temperature throughout the study period. We attempted to detect rickettsial DNA from peripheral blood and aspiration samples from kidney and spleen by nested PCR, but all samples examined were negative. The control dog lacked detectable titers to R. japonica antigen on day 14, while positive antibodies to R. japonica were detected in all four experimentally infected dogs, with titers of 1:160 to 1:80. In the epidemiologic survey, 24 (1.8%) of the 1,363 dogs examined throughout Japan had antibodies against R. japonica, with titers of 1:40 or more. However, we observed neither clinical signs at the time of sample collection nor nested PCR results indicative of rickettsial infection in these dogs. In conclusion, dogs in Japan can be exposed to R. japonica, and infected dogs with immunosuppressive conditions can temporarily develop clinical symptoms, including fever, anorexia, depression, and decreased water consumption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980481"}
{"pmid": "20980483", "title": "No association of abnormal cranial venous drainage with multiple sclerosis: a magnetic resonance venography and flow-quantification study.", "content": "No association of abnormal cranial venous drainage with multiple sclerosis: a magnetic resonance venography and flow-quantification study. Recent studies using colour-coded Doppler sonography showed that chronic impaired venous drainage from the central nervous system is almost exclusively found in multiple sclerosis (MS) patients. This study aimed to investigate the intracranial and extracranial venous anatomy and the intracerebral venous flow profile in patients with MS and healthy controls using magnetic resonance venography (MRV). Twenty patients with definite MS and 20 age- and gender-matched healthy controls were examined. MR imaging was performed on a whole-body 3T MR system including both 3D phase-contrast and dynamic 3D contrast-enhanced MRV as well as flow quantification of the internal cerebral veins and the straight sinus. Image analysis was performed by two experienced interventional neuroradiologists blinded to clinical data and structural brain imaging. The intracranial and extracranial neck veins were analysed for stenosis/occlusion and alternative venous drainage pattern. A completely normal venous anatomy was observed in 10 MS patients and 12 controls. Anomalies of the venous system (venous stenosis/occlusions) were found in 10 MS patients and eight healthy controls. An anomalous venous system in combination with associated alternative venous drainage was observed in six MS patients and five healthy controls. Flow quantification showed no venous backflow in any MS patient or control. Findings suggestive of anomalies of the cranial venous outflow anatomy were frequently observed in both MS patients and healthy controls. Given the normal intracranial venous flow quantification results, it is likely that these findings reflect anatomical variants of venous drainage rather than clinically relevant venous outflow obstructions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980483"}
{"pmid": "20980482", "title": "Escherichia coli K88ac fimbriae expressing heat-labile and heat-stable (STa) toxin epitopes elicit antibodies that neutralize cholera toxin and STa toxin and inhibit adherence of K88ac fimbrial E. coli.", "content": "Escherichia coli K88ac fimbriae expressing heat-labile and heat-stable (STa) toxin epitopes elicit antibodies that neutralize cholera toxin and STa toxin and inhibit adherence of K88ac fimbrial E. coli. Enterotoxigenic Escherichia coli (ETEC) strains are a major cause of diarrheal disease in humans and animals. Bacterial adhesins and heat-labile (LT) and heat-stable (ST) enterotoxins are the virulence determinants in ETEC diarrhea. It is believed that vaccines inducing anti-adhesin immunity to inhibit bacterial adherence and anti-toxin immunity to eliminate toxin activity would provide broad-spectrum protection against ETEC. In this study, an ETEC fimbrial adhesin was used as a platform to express LT and STa for adhesin-toxin fusion antigens to induce anti-toxin and anti-adhesin immunity. An epitope from the B subunit of LT toxin (LTP1, (8)LCSEYRNTQIYTIN(21)) and an STa toxoid epitope ((5)CCELCCNPQCAGCY(18)) were embedded in the FaeG major subunit of E. coli K88ac fimbriae. Constructed K88ac-toxin chimeric fimbriae were harvested and used for rabbit immunization. Immunized rabbits developed anti-K88ac, anti-LT, and anti-STa antibodies. Moreover, induced antibodies not only inhibited adherence of K88ac fimbrial E. coli to porcine small intestinal enterocytes but also neutralized cholera toxin and STa toxin. Data from this study demonstrated that K88ac fimbriae expressing LT and STa epitope antigens elicited neutralizing anti-toxin antibodies and anti-adhesin antibodies and suggested that E. coli fimbriae could serve as a platform for the development of broad-spectrum vaccines against ETEC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980482"}
{"pmid": "20980484", "title": "Functional role of ipsilateral motor areas in multiple sclerosis.", "content": "Functional role of ipsilateral motor areas in multiple sclerosis. In patients with multiple sclerosis (MS), motor tasks are associated with increased activation of ipsilateral motor cortical areas. The authors examined the role of two ipsilateral motor areas during performance of a simple motor task in MS patients in relation to their motor impairment and CNS injury. Single pulses of transcranial magnetic stimulation (TMS) were used to interfere transiently with neuronal processing in the contralateral (M1(CONTRA)) or ipsilateral (M1(IPSI)) primary motor cortex or ipsilateral dorsal premotor cortex (PMd(IPSI)) during a simple reaction time (RT) task in 26 right-handed patients with moderately severe stable MS and matched healthy controls. Subjects responded to an auditorily presented Go signal as quickly as possible by performing isometric right-thumb abductions. TMS was applied 100 ms after the Go signal. Motor impairment was evaluated by hand function tests. CNS injury was assessed by magnetic resonance spectroscopy (normalised N-acetyl-aspartate spectra, NAA/Cr), by the total cerebral T2-weighted MRI hyperintense lesion load, and by corticomuscular latency (CML) to the abductor pollicis brevis muscle. TMS applied to M1(CONTRA) slowed RT in patients and controls. In contrast, stimulation of M1(IPSI) or PMd(IPSI) increased RT only in MS patients. In patients, the relative RT changes following TMS over M1(IPSI) or PMd(IPSI) did not correlate with any of the motor function tests or with NAA/Cr or total cerebral lesion load. However, RT changes following TMS over M1(IPSI) correlated inversely with CML. Recruitment of ipsilateral motor areas may be a functionally relevant, yet limited adaptive response to chronic brain injury in MS patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980484"}
{"pmid": "20980486", "title": "Efficacy of Bifidobacterium breve and Lactobacillus casei oral supplementation on necrotizing enterocolitis in very-low-birth-weight preterm infants: a double-blind, randomized, controlled trial.", "content": "Efficacy of Bifidobacterium breve and Lactobacillus casei oral supplementation on necrotizing enterocolitis in very-low-birth-weight preterm infants: a double-blind, randomized, controlled trial. Probiotics are used for the prevention of necrotizing enterocolitis (NEC) because of their positive effects on intestinal motor function, modulation of inflammatory response, and mucosal barrier function. The objective was to assess whether the combined use of Lactobacillus casei and Bifidobacterium breve may prevent the occurrence of NEC stage ≥ 2 by the criteria of Bell in very-low-birth-weight preterm infants. A double-blind, randomized, controlled clinical trial was conducted in 231 preterm infants weighing from 750 to 1499 g at birth. The intervention group was composed of 119 infants who received human milk with probiotic supplementation (B. breve and L. casei) and a control group of 112 infants who received human milk containing no probiotics. The primary outcome was the occurrence of NEC stage ≥ 2 as defined by Bell's modified criteria. Four confirmed cases of NEC stage ≥ 2 by Bell's criteria occurred only in the control group. Oral supplementation of B. breve and L. casei reduced the occurrence of NEC (Bell's stage ≥ 2). It was considered that an improvement in intestinal motility might have contributed to this result. This trial was registered at www.isrctin.org as number 67165178 (International Standard Randomized Controlled Trial).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980486"}
{"pmid": "20980485", "title": "Vitamin D and breast cancer recurrence in the Women's Healthy Eating and Living (WHEL) Study.", "content": "Vitamin D and breast cancer recurrence in the Women's Healthy Eating and Living (WHEL) Study. There is a paucity of research evaluating the relation between vitamin D and recurrence of breast cancer after treatment. This study was designed to evaluate the associations between circulating concentrations of 25-hydroxyvitamin D [25(OH)D] and dietary, supplemental, and total intake of vitamin D and recurrent or new breast cancer events within the Women's Healthy Eating and Living (WHEL) Study. A prospective cohort study design (n = 3085) was used to evaluate the relation between dietary, supplemental, and total vitamin D intake and recurrent breast cancer, and a nested case-control study with 512 matched pairs was used for analysis of the association between 25(OH)D and breast cancer recurrence. No relation between 25(OH)D and breast cancer recurrence was observed. Compared with women with serum concentrations of 25(OH)D ≥ 30 ng/mL, adjusted odds ratios (95% CI) for breast cancer recurrence were 1.14 (0.57, 2.31) for those with concentrations < 10 ng/mL, 1.00 (0.68-1.48) for concentrations ≥ 10 and < 20 ng/mL, and 1.05 (0.76, 1.47) for concentrations ≥ 20 and < 30 ng/mL. No significant associations were observed when analyses were stratified by pre- and postmenopausal status or for local, regional, or distant recurrence or death. Vitamin D intake was not related to breast cancer recurrence overall, although for premenopausal women there was a significant inverse association between dietary vitamin D intake and recurrence (P for trend = 0.02). These results do not provide support for a relation between concentrations of 25(OH)D after treatment and the recurrence of breast cancer. This trial is registered at clinicaltrials.gov for the WHEL Study as NCT00003787.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980485"}
{"pmid": "20980488", "title": "Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study.", "content": "Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. The long-term role of fatty acids (FAs) in the cause of diabetes remains largely unclear. We aimed to investigate erythrocyte membrane FAs, desaturase activity, and dietary FAs in relation to the incidence of type 2 diabetes. We applied a nested case-cohort design (n = 2724, including 673 incident diabetes cases) within the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study, which involves 27,548 middle-aged subjects. Thirty erythrocyte membrane FAs (percentage of total FAs) and FA intake (percentage of total fat) were measured at baseline, and physician-confirmed incident diabetes was assessed during a mean follow-up of 7.0 y. We evaluated Δ⁵ desaturase (D5D) and Δ⁶ desaturase (D6D) activity by using FA product-to-precursor ratios (traditional approach) and by investigating variants in FADS1 and FADS2 genes that encode these desaturases (Mendelian randomization approach). As a main finding, erythrocyte 16:1n-7 and 18:3n-6 and FA ratios, which reflect stearoyl coenzyme A desaturase (SCD) and D6D activity, were directly related to diabetes risk in multivariable-adjusted models [relative risks (95% CIs) comparing extreme quintiles: 16:1n-7, 2.11 (1.46, 3.05); 18:3n-6, 2.00 (1.38, 2.88); SCD, 2.61 (1.75, 3.89); and D6D, 2.46 (1.67, 3.63)], whereas the FA ratio that reflects D5D activity was inversely associated with risk [0.46 (0.31, 0.70)]. The Mendelian randomization approach corroborated the direct relation for D6D activity and tended to support the inverse relation for D5D activity. Proportions of dietary FAs showed only modest to low correlations with erythrocyte FAs and were not significantly associated with risk. The FA profile of erythrocyte membrane phospholipids and activity of desaturase enzymes are strongly linked to the incidence of type 2 diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980488"}
{"pmid": "20980487", "title": "Fatty acid consumption and risk of fracture in the Women's Health Initiative.", "content": "Fatty acid consumption and risk of fracture in the Women's Health Initiative. Fatty acids (FAs) may be important dietary components that modulate osteoporotic fracture risk. The objective was to examine FA intake in relation to osteoporotic fractures. The participants were postmenopausal women enrolled in the Women's Health Initiative (n = 137,486). Total fractures were identified by self-report; hip fractures were confirmed by medical record review. FA intake was estimated from baseline food-frequency questionnaires and standardized to total caloric intake. No data on omega-3 (n-3) FA supplements were available. Cox proportional hazard models were constructed to estimate risk of fracture. Higher saturated FA consumption was associated with higher hip fracture risk [quartile 4 multivariate-adjusted hazard ratio (HR): 1.31; 95% CI: 1.11, 1.55; P for trend = 0.001]. Lower total fracture risk was associated with a higher monounsaturated FA intake (quartile 3 HR: 0.94; 95% CI: 0.89, 0.98; P for trend = 0.050) and polyunsaturated FA intake (quartile 4 HR: 0.95; 95% CI: 0.90, 0.99; P for trend = 0.019). Unexpectedly, higher consumption of marine n-3 FAs was associated with greater total fracture risk (quartile 4 HR: 1.07; 95% CI: 1.02, 1.12; P for trend = 0.010), whereas a higher n-6 FA intake was associated with a lower total fracture risk (quartile 4 HR: 0.94; 95% CI: 0.89, 0.98; P for trend 0.009). These results suggest that saturated FA intake may significantly increase hip fracture risk, whereas monounsaturated and polyunsaturated FA intakes may decrease total fracture risk. In postmenopausal women with a low intake of marine n-3 FAs, a higher intake of n-6 FAs may modestly decrease total fracture risk. This trial was registered at clinicaltrials.gov as NCT00000611.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980487"}
{"pmid": "20980489", "title": "Intake of probiotic food and risk of spontaneous preterm delivery.", "content": "Intake of probiotic food and risk of spontaneous preterm delivery. Preterm delivery represents a substantial problem in perinatal medicine worldwide. Current knowledge on potential influences of probiotics in food on pregnancy complications caused by microbes is limited. We hypothesized that intake of food with probiotics might reduce pregnancy complications caused by pathogenic microorganisms and, through this, reduce the risk of spontaneous preterm delivery. This study was performed in the Norwegian Mother and Child Cohort on the basis of answers to a food-frequency questionnaire. We studied intake of milk-based products containing probiotic lactobacilli and spontaneous preterm delivery by using a prospective cohort study design (n = 950 cases and 17,938 controls) for the pregnancy outcome of spontaneous preterm delivery (< 37 gestational weeks). Analyses were adjusted for the covariates of parity, maternal educational level, and physical activity. Pregnancies that resulted in spontaneous preterm delivery were associated with any intake of milk-based probiotic products in an adjusted model [odds ratio (OR): 0.857; 95% CI: 0.741, 0.992]. By categorizing intake into none, low, and high intakes of the milk-based probiotic products, a significant association was observed for high intake (OR: 0.820; 95% CI: 0.681, 0.986). Women who reported habitual intake of probiotic dairy products had a reduced risk of spontaneous preterm delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980489"}
{"pmid": "20980490", "title": "Rice intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study.", "content": "Rice intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study. Refined carbohydrates have been suggested to deteriorate glucose metabolism; however, whether persons with elevated intakes of white rice, which is a major staple food for the Japanese, experience increased risk of developing type 2 diabetes remains unclear. We prospectively investigated the association between white rice intake and risk of type 2 diabetes. Participants were 25,666 men and 33,622 women aged 45-75 y who participated in the second survey of the Japan Public Health Center-based Prospective Study and who had no prior history of diabetes. We ascertained food intake by using a validated 147-item food-frequency questionnaire. Odds ratios of self-reported, physician-diagnosed type 2 diabetes over 5 y were estimated by using logistic regressions. A total of 1103 new cases of type 2 diabetes were self-reported. There was a significant association between rice intake and an increased risk of type 2 diabetes in women; the multivariate-adjusted odds ratio for the highest compared with lowest quartiles of rice intake was 1.65 (95% CI: 1.06, 2.57; P for trend = 0.005). In men, the association was unclear, although there was a suggestion of a positive association in persons who were not engaged in strenuous physical activity (P for trend = 0.08). Elevated intake of white rice is associated with an increased risk of type 2 diabetes in Japanese women. The finding that is suggestive of a positive association of rice intake in physically inactive men deserves further investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980490"}
{"pmid": "20980491", "title": "Dietary omega-3 fatty acids and fish consumption and risk of type 2 diabetes.", "content": "Dietary omega-3 fatty acids and fish consumption and risk of type 2 diabetes. Although dietary omega-3 (n-3) fatty acids may confer some cardiovascular benefits, it is unclear whether these nutrients may also unfavorably affect risk of type 2 diabetes (T2D). We evaluated whether dietary omega-3 fatty acids and fish consumption were associated with increased risk of T2D. This was a prospective study of 36,328 women (mean age: 54.6 y) who participated in the Women's Health Study and who were followed from 1992 to 2008. Incident T2D was self-reported and validated primarily through the collection of supplementary information from participants. Information on omega-3 and fish intakes was obtained by using a validated food-frequency questionnaire. We used Cox proportional hazard models to estimate adjusted relative risks. During an average follow-up of 12.4 y, 2370 women developed T2D. Marine but not plant-based omega-3 fatty acids were positively associated with incident T2D. From the lowest to highest quintiles of marine omega-3 intake, the multivariable-adjusted hazard ratios (95% CIs) for T2D were 1.0 (referent), 1.17 (1.03, 1.33), 1.20 (1.05, 1.38), 1.46 (1.28, 1.66), and 1.44 (1.25, 1.65), respectively (P for trend < 0.0001). A similar association was observed with fish intake, but additional adjustment for docosahexaenoic acid led to the elimination of the association. The relation between marine omega-3 fatty acids and T2D was observed in hypertensive and nonhypertensive subjects and in women who reported infrequent fish consumption. Our data suggest an increased risk of T2D with the intake of long-chain omega-3 fatty acids, especially with higher intakes (≥ 0.20 g omega-3/d or ≥ 2 servings of fish/d). The Women's Health Study was registered at clinicaltrials.gov as NCT00000479.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980491"}
{"pmid": "20980492", "title": "The identification of children with adverse risk factor levels by body mass index cutoffs from 2 classification systems: the Bogalusa Heart Study.", "content": "The identification of children with adverse risk factor levels by body mass index cutoffs from 2 classification systems: the Bogalusa Heart Study. The cutoffs from the Centers for Disease Control and Prevention (CDC) growth charts and from the Cooper Institute (FitnessGram) are widely used to identify children who have a high body mass index (BMI). We compared the abilities of these 2 systems to identify children who have adverse lipid concentrations and blood pressure measurements and the reliability (consistency) of each classification system over time (mean follow-up: 7 y). A cross-sectional analysis based on data from 22,896 examinations of 5- to 17-y-olds was conducted. Principal components analyses were used to summarize levels of the 5 risk factors, and likelihood ratios and the κ statistic were used to compare the screening abilities of the 2 systems. Of these children, 3972 were included in longitudinal analyses. There were marked differences in the prevalence of a high FitnessGram BMI by age, with the prevalence among boys increasing from 2.5% to 21% between the ages of 5 and 11 y. The identification of adverse risk factors by the 2 systems was only fair (κ = 0.25), but there was little difference in the abilities of the CDC and FitnessGram cutoffs to identify high-risk children. Longitudinal analyses, however, indicated that the agreement between initial and follow-up FitnessGram classifications was substantially lower than that based on CDC cutoffs (κ = 0.28 compared with 0.49). The FitnessGram and CDC cutoffs have similar abilities to identify high-risk children. However, a high FitnessGram BMI is difficult to interpret because the reliability over time is low, and the prevalence increases markedly with age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980492"}
{"pmid": "20980493", "title": "A dose-finding trial of the effect of long-term folic acid intervention: implications for food fortification policy.", "content": "A dose-finding trial of the effect of long-term folic acid intervention: implications for food fortification policy. The lowest dose of folic acid required to achieve effective reductions in homocysteine is controversial but important for food fortification policy given recent concerns about the potential adverse effects of overexposure to this vitamin. We compared the effectiveness of 0.2 mg folic acid/d with that of 0.4 and 0.8 mg/d at lowering homocysteine concentrations over a 6-mo period. A randomized dose-finding trial with folic acid was conducted. Of 203 participants screened, 101 patients with ischemic heart disease and 71 healthy volunteers completed the study. Participants were randomly assigned to receive placebo or folic acid at doses of 0.2, 0.4, or 0.8 mg/d for 26 wk; subsamples of patients with ischemic heart disease were also examined at 6 or 12 wk. Participants with higher baseline homocysteine concentrations had the greatest reductions in homocysteine in response to folic acid doses of 0.2 mg (-20.6%), 0.4 mg (-20.7%), and 0.8 mg (-27.8%); in those with lower baseline homocysteine concentrations, the responses were -8.2%, -8.9%, and -8.3%, respectively. No significant differences in homocysteine responses to the different doses were observed. In the patient group sampled at intervals during the intervention, the maximal homocysteine response appeared to be achieved by 6 wk in the 0.8-mg/d group and by 12 wk in the 0.4-mg/d group. However, the homocysteine response was suboptimal in the 0.2-mg/d group at both 6 and 12 wk compared with that at 26 wk. A folic acid dose as low as 0.2 mg/d can, if administered for 6 mo, effectively lower homocysteine concentrations. Higher doses may not be necessary because they result in no further significant lowering, whereas doses even lower than 0.2 mg/d may be effective in the longer term. Previous trials probably overestimated the folic acid dose required because of a treatment duration that was too short. This trial was registered at clinicaltrials.gov as ISRCTN45296887.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980493"}
{"pmid": "20980494", "title": "A low-glycemic index diet combined with exercise reduces insulin resistance, postprandial hyperinsulinemia, and glucose-dependent insulinotropic polypeptide responses in obese, prediabetic humans.", "content": "A low-glycemic index diet combined with exercise reduces insulin resistance, postprandial hyperinsulinemia, and glucose-dependent insulinotropic polypeptide responses in obese, prediabetic humans. The optimal lifestyle intervention that reverses diabetes risk factors is not known. We examined the effect of a low-glycemic index (GI) diet and exercise intervention on glucose metabolism and insulin secretion in obese, prediabetic individuals. Twenty-two participants [mean ± SEM age: 66 ± 1 y; body mass index (in kg/m(2)): 34.4 ± 0.8] underwent a 12-wk exercise-training intervention (1 h/d for 5 d/wk at ≈ 85% of maximum heart rate) while randomly assigned to receive either a low-GI diet (LoGIX; 40 ± 0.3 units) or a high-GI diet (HiGIX; 80 ± 0.6 units). Body composition (measured by using dual-energy X-ray absorptiometry and computed tomography), insulin sensitivity (measured with a hyperinsulinemic euglycemic clamp with [6,6-(2)H(2)]-glucose), and oral glucose-induced insulin and incretin hormone secretion were examined. Both groups lost equal amounts of body weight (-8.8 ± 0.9%) and adiposity and showed similar improvements in peripheral tissue (+76.2 ± 14.9%) and hepatic insulin sensitivity (+27.1 ± 7.1%) (all P < 0.05). However, oral glucose-induced insulin secretion was reduced only in the LoGIX group (6.59 ± 0.86 nmol in the prestudy compared with 4.70 ± 0.67 nmol in the poststudy, P < 0.05), which was a change related to the suppressed postprandial response of glucose-dependent insulinotropic polypeptide. When corrected for changes in β cell glucose exposure, changes in insulin secretion were attenuated in the LoGIX group but became significantly elevated in the HiGIX group. Although lifestyle-induced weight loss improves insulin resistance in prediabetic individuals, postprandial hyperinsulinemia is reduced only when a low-GI diet is consumed. In contrast, a high-GI diet impairs pancreatic β cell and intestinal K cell function despite significant weight loss. These findings highlight the important role of the gut in mediating the effects of a low-GI diet on type 2 diabetes risk reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980494"}
{"pmid": "20980495", "title": "The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter.", "content": "The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter. High-titer autologous neutralizing antibody responses have been demonstrated during early subtype C human immunodeficiency virus type 1 (HIV-1) infection. However, characterization of this response against autologous virus at the monoclonal antibody (MAb) level has only recently begun to be elucidated. Here we describe five monoclonal antibodies derived from a subtype C-infected seroconverter and their neutralizing activities against pseudoviruses that carry envelope glycoproteins from 48 days (0 month), 2 months, and 8 months after the estimated time of infection. Sequence analysis indicated that the MAbs arose from three distinct B cell clones, and their pattern of neutralization compared to that in patient plasma suggested that they circulated between 2 and 8 months after infection. Neutralization by MAbs representative of each B cell clone was mapped to two residues: position 134 in V1 and position 189 in V2. Mutational analysis revealed cooperative effects between glycans and residues at these two positions, arguing that they contribute to a single epitope. Analysis of the cognate gp120 sequence through homology modeling places this potential epitope near the interface between the V1 and V2 loops. Additionally, the escape mutation R189S in V2, which conferred resistance against all three MAbs, had no detrimental effect on virus replication in vitro. Taken together, our data demonstrate that independent B cells repeatedly targeted a single structure in V1V2 during early infection. Despite this assault, a single amino acid change was sufficient to confer complete escape with minimal impact on replication fitness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980495"}
{"pmid": "20980497", "title": "A vaccinia virus deletion mutant reveals the presence of additional inhibitors of NF-kappaB.", "content": "A vaccinia virus deletion mutant reveals the presence of additional inhibitors of NF-kappaB. The classical nuclear factor kappa B (NF-κB) signaling pathway is an important regulator of inflammation and innate immunity that is activated by a wide variety of stimuli, including virus infection, tumor necrosis factor alpha (TNF-α), and interleukin 1β (IL-1β). Poxviruses, including vaccinia virus (VV) and ectromelia virus, encode multiple proteins that function in immune evasion. Recently, a growing number of genes encoded by poxviruses have been shown to target and disrupt the NF-κB signaling pathway. To determine if additional gene products that interfere with NF-κB signaling existed, we used a vaccinia virus deletion mutant, VV811, which is missing 55 open reading frames lacking all known inhibitors of TNF-α-induced NF-κB activation. Immunofluorescence analysis of HeLa cells treated with TNF-α and IL-1β revealed that NF-κB translocation to the nucleus was inhibited in VV811-infected cells. This was further confirmed through Western blotting of cytoplasmic and nuclear extracts for NF-κB. Additionally, VV811 infection inhibited TNF-α-induced IκBα degradation. In contrast to vaccinia virus strain Copenhagen (VVCop)-infected cells, VV811 infection resulted in the dramatic accumulation of phosphorylated IκBα. Correspondingly, coimmunoprecipitation assays demonstrated that the NF-κB-inhibitory IκBα-p65-p50 complex was intact in VV811-infected cells. Significantly, cells treated with 1-β-d-arabinofuranosylcytosine, an inhibitor of poxvirus late gene expression, demonstrated that an additional vaccinia virus late gene was involved in the stabilization of IκBα. Overall, this work indicates that unidentified inhibitors of NF-κB exist in vaccinia virus. The complex inhibition of NF-κB by vaccinia virus illustrates the importance of NF-κB activation in the antiviral response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980497"}
{"pmid": "20980496", "title": "Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA.", "content": "Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA. The origin-binding domain (OBD) of simian virus 40 (SV40) large T-antigen (T-Ag) is essential for many of T-Ag's interactions with DNA. Nevertheless, many important issues related to DNA binding, for example, how single-stranded DNA (ssDNA) transits along the T-Ag OBD, have yet to be established. Therefore, X-ray crystallography was used to determine the costructure of the T-Ag OBD bound to DNA substrates such as the single-stranded region of a forked oligonucleotide. A second structure of the T-Ag OBD crystallized in the presence of poly(dT)(12) is also reported. To test the conclusions derived from these structures, residues identified as being involved in binding to ssDNA by crystallography or by an earlier nuclear magnetic resonance study were mutated, and their binding to DNA was characterized via fluorescence anisotropy. In addition, these mutations were introduced into full-length T-Ag, and these mutants were tested for their ability to support replication. When considered in terms of additional homology-based sequence alignments, our studies refine our understanding of how the T-Ag OBDs encoded by the polyomavirus family interact with ssDNA, a critical step during the initiation of DNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980496"}
{"pmid": "20980499", "title": "Poliovirus RNA is released from the capsid near a twofold symmetry axis.", "content": "Poliovirus RNA is released from the capsid near a twofold symmetry axis. After recognizing and binding to its host cell, poliovirus (like other nonenveloped viruses) faces the challenge of translocating its genome across a cellular membrane and into the cytoplasm. To avoid entanglement with the capsid, the RNA must exit via a single site on the virion surface. However, the mechanism by which a single site is selected (from among 60 equivalents) is unknown; and until now, even its location on the virion surface has been controversial. To help to elucidate the mechanism of infection, we have used single-particle cryo-electron microscopy and tomography to reconstruct conformationally altered intermediates that are formed by the poliovirion at various stages of the poliovirus infection process. Recently, we reported icosahedrally symmetric structures for two forms of the end-state 80S empty capsid particle. Surprisingly, RNA was frequently visible near the capsid; and in a subset of the virions, RNA was seen on both the inside and outside of the capsid, caught in the act of exiting. To visualize RNA exiting, we have now determined asymmetric reconstructions from that subset, using both single-particle cryo-electron microscopy and cryo-electron tomographic methods, producing independent reconstructions at ∼50-Å resolution. Contrary to predictions in the literature, the footprint of RNA on the capsid surface is located close to a viral 2-fold axis, covering a slot-shaped area of reduced density that is present in both of the symmetrized 80S reconstructions and which extends by about 20 Å away from the 2-fold axis toward each neighboring 5-fold axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980499"}
{"pmid": "20980498", "title": "Template recognition mechanisms by replicase proteins differ between bipartite positive-strand genomic RNAs of a plant virus.", "content": "Template recognition mechanisms by replicase proteins differ between bipartite positive-strand genomic RNAs of a plant virus. Recognition of RNA templates by viral replicase proteins is one of the key steps in the replication process of all RNA viruses. However, the mechanisms underlying this phenomenon, including primary RNA elements that are recognized by the viral replicase proteins, are not well understood. Here, we used aptamer pulldown assays with membrane fractionation and protein-RNA coimmunoprecipitation in a cell-free viral translation/replication system to investigate how viral replicase proteins recognize the bipartite genomic RNAs of the Red clover necrotic mosaic virus (RCNMV). RCNMV replicase proteins bound specifically to a Y-shaped RNA element (YRE) located in the 3' untranslated region (UTR) of RNA2, which also interacted with the 480-kDa replicase complexes that contain viral and host proteins. The replicase-YRE interaction recruited RNA2 to the membrane fraction. Conversely, RNA1 fragments failed to interact with the replicase proteins supplied in trans. The results of protein-RNA coimmunoprecipitation assays suggest that RNA1 interacts with the replicase proteins coupled with their translation. Thus, the initial template recognition mechanisms employed by the replicase differ between RCNMV bipartite genomic RNAs and RNA elements are primary determinants of the differential replication mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980498"}
{"pmid": "20980501", "title": "A nuclear inhibitor of NF-kappaB encoded by a poxvirus.", "content": "A nuclear inhibitor of NF-kappaB encoded by a poxvirus. Poxviruses have evolved various strategies to inhibit cytoplasmic events leading to activation of the nuclear factor κB (NF-κB) signaling pathway, with individual viruses often encoding multiple NF-κB inhibitors. Here, the novel orf virus (ORFV)-encoded protein ORFV002 was shown to inhibit nuclear events regulating NF-κB transcriptional activity. ORFV002 expression in cell cultures significantly decreased wild-type-virus-, tumor necrosis factor alpha (TNF-α)-, and lipopolysaccharide (LPS)-induced NF-κB-mediated gene expression. Expression of ORFV002 in cells, while not affecting phosphorylation or nuclear translocation of NF-κB-p65, markedly decreased TNF-α- and wild-type-virus-induced acetylation of NF-κB-p65, a p300-mediated nuclear modification of NF-κB-p65 that regulates its transactivating activity. ORFV002 was shown to colocalize and interact with NF-κB-p65, and expression of ORFV002 in cell cultures resulted in a reduced interaction of NF-κB-p65 with p300, suggesting that ORFV002 interferes with NF-κB-p65/p300 association. Deletion of ORFV002 from the OV-IA82 genome had no significant effect on ORFV pathogenesis in sheep, indicating that ORFV002 is nonessential for virus virulence in the natural host. This represents the first description of a nuclear inhibitor of NF-κB encoded by a poxvirus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980501"}
{"pmid": "20980502", "title": "Cytomegalovirus microRNA expression is tissue specific and is associated with persistence.", "content": "Cytomegalovirus microRNA expression is tissue specific and is associated with persistence. MicroRNAs (miRNAs) are a class of small noncoding RNAs involved in posttranscriptional regulation. miRNAs are utilized in organisms ranging from plants to higher mammals, and data have shown that DNA viruses also use this method for host and viral gene regulation. Here, we report the sequencing of the small RNAs in rat cytomegalovirus (RCMV)-infected fibroblasts and persistently infected salivary glands. We identified 24 unique miRNAs that mapped to hairpin structures found within the viral genome. While most miRNAs were detected in both samples, four were detected exclusively in the infected fibroblasts and two were specific for the infected salivary glands. The RCMV miRNAs are distributed across the viral genome on both the positive and negative strands, with clusters of miRNAs at a number of locations, including near viral genes r1 and r111. The RCMV miRNAs have a genomic positional orientation similar to that of the miRNAs described for mouse cytomegalovirus, but they do not share any substantial sequence conservation. Similar to other reported miRNAs, the RCMV miRNAs had considerable variation at their 3' and 5' ends. Interestingly, we found a number of specific examples of differential isoform usage between the fibroblast and salivary gland samples. We determined by real-time PCR that expression of the RCMV miRNA miR-r111.1-2 is highly expressed in the salivary glands and that miR-R87-1 is expressed in most tissues during the acute infection phase. Our study identified the miRNAs expressed by RCMV in vitro and in vivo and demonstrated that expression is tissue specific and associated with a stage of viral infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980502"}
{"pmid": "20980500", "title": "Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7.", "content": "Differential regulation of human papillomavirus type 8 by interferon regulatory factors 3 and 7. The genus β human papillomavirus (HPV) type 8 is associated with nonmelanoma skin cancer in patients with epidermodysplasia verruciformis, and evidence for its protumorigenic potential in the general population increases. To date, strategies to suppress genus β HPV infections are limited. Interferon regulatory factors IRF-3 and IRF-7 play key roles in the activation of the innate immune response to viral infections. In this study, we show for the first time that both IRF-3 and IRF-7 regulate transcription of a papillomavirus, but with opposing effects. IRF-7, expressed in the suprabasal layers of human epidermis, increased HPV8 late promoter activity via direct binding to viral DNA. UV-B light-induced activation of the HPV8 promoter involved IRF-7 as a downstream effector. In contrast, IRF-3, expressed in all layers of human epidermis, induced strong HPV8 suppression in primary keratinocytes. IRF-3-mediated suppression prevailed over IRF-7-induced HPV8 transcription. Unlike the E6 oncoprotein of the mucosal high-risk HPV16, the HPV8 E6 protein did not bind to IRF-3 and only weakly antagonized its activity. Strong antiviral activity was also observed, when keratinocytes were treated with potent IRF-3 activators, poly(I:C) or RNA bearing 5' phosphates. In conclusion, we show that IRF-3 activation induces a state of cell-autonomous immunity against HPV in primary human keratinocytes. Our study suggests that local application of IRF-3-activating compounds might constitute an attractive novel therapeutic strategy against HPV8-associated diseases, particularly in epidermodysplasia verruciformis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980500"}
{"pmid": "20980504", "title": "Function of the small hydrophobic protein of J paramyxovirus.", "content": "Function of the small hydrophobic protein of J paramyxovirus. At 18,954 nucleotides, the J paramyxovirus (JPV) genome is one of the largest in the family Paramyxoviridae, consisting of eight genes in the order 3'-N-P/V/C-M-F-SH-TM-G-L-5'. To study the function of novel paramyxovirus genes in JPV, a plasmid containing a full-length cDNA clone of the genome of JPV was constructed. In this study, the function of the small hydrophobic (SH) protein of JPV was examined by generating a recombinant JPV lacking the coding sequence of the SH protein (rJPVΔSH). rJPVΔSH was viable and had no growth defect in tissue culture cells. However, more tumor necrosis factor alpha (TNF-α) was produced during rJPVΔSH infection, suggesting that SH plays a role in inhibiting TNF-α production. rJPVΔSH induced more apoptosis in tissue culture cells than rJPV. Virus-induced apoptosis was inhibited by neutralizing antibody against TNF-α, suggesting that TNF-α contributes to JPV-induced apoptosis in vitro. The expression of JPV SH protein inhibited TNF-α-induced NF-κB activation in a reporter gene assay, suggesting that JPV SH protein can inhibit TNF-α signaling in vitro. Furthermore, infection of mice with rJPVΔSH induced more TNF-α expression, indicating that SH plays a role in blocking TNF-α expression in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980504"}
{"pmid": "20980503", "title": "Adenovirus membrane penetration activates the NLRP3 inflammasome.", "content": "Adenovirus membrane penetration activates the NLRP3 inflammasome. Adenovirus type 5 (Ad5) infection of macrophages results in rapid secretion of interleukin-1β (IL-1β) and is dependent on the inflammasome components NLRP3 and ASC and the catalytic activity of caspase-1. Using lentivirus-expressed short hairpin RNA (shRNA) and competitive inhibitors, we show that Ad-induced IL-1β release is dependent upon Toll-like receptor 9 (TLR9) sensing of the Ad5 double-stranded DNA (dsDNA) genome in human cell lines and primary monocyte-derived macrophages but not in mouse macrophages. Additionally, a temperature-sensitive mutant of Ad5 unable to penetrate endosomal membranes, ts1, is unable to induce IL-1β release in TLR2-primed THP-1 cells, suggesting that penetration of endosomal membranes is required for IL-1β release. Disruption of lysosomal membranes and the release of cathepsin B into the cytoplasm are required for Ad-induced NLRP3 activation. Ad5 cell entry also induces reactive oxygen species (ROS) production, and inhibitors of ROS prevent Ad-induced IL-1β release. Ad5 activation of NLRP3 also induces necrotic cell death, resulting in the release of the proinflammatory molecule HMGB1. This work further defines the mechanisms of virally induced inflammasome activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980503"}
{"pmid": "20980505", "title": "Translational control of the abundance of cytoplasmic poly(A) binding protein in human cytomegalovirus-infected cells.", "content": "Translational control of the abundance of cytoplasmic poly(A) binding protein in human cytomegalovirus-infected cells. Irrespective of their effects on ongoing host protein synthesis, productive replication of the representative alphaherpesvirus herpes simplex virus type 1, the representative gammaherpesvirus Kaposi's sarcoma herpesvirus, and the representative betaherpesvirus human cytomegalovirus [HCMV] stimulates the assembly of the multisubunit, cap-binding translation factor eIF4F. However, only HCMV replication is associated with an increased abundance of eIF4F core components (eIF4E, eIF4G, eIF4A) and the eIF4F-associated factor poly(A) binding protein (PABP). Here, we demonstrate that the increase in translation factor concentration was readily detected in an asynchronous population of HCMV-infected primary human fibroblasts, abolished by prior UV inactivation of virus, and genetically dependent upon viral immediate-early genes. Strikingly, while increased mRNA steady-state levels accompanied the rise in eIF4E and eIF4G protein levels, the overall abundance of PABP mRNA, together with the half-life of the polypeptide it encodes, remained relatively unchanged by HCMV infection. Instead, HCMV-induced PABP accumulation resulted from new protein synthesis and was sensitive to the mTORC1-selective inhibitor rapamycin, which interferes with phosphorylation of the mTORC1 substrate p70 S6K and the translational repressor 4E-BP1. While virus-induced PABP accumulation did not require p70 S6K, it was inhibited by the expression of a dominant-acting 4E-BP1 variant unable to be inactivated by mTORC1. Finally, unlike the situation in alpha- or gammaherpesvirus-infected cells, where PABP is redistributed to nuclei, PABP accumulated in the cytoplasm of HCMV-infected cells. Thus, cytoplasmic PABP accumulation is translationally controlled in HCMV-infected cells via a mechanism requiring mTORC1-mediated inhibition of the cellular 4E-BP1 translational repressor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980505"}
{"pmid": "20980506", "title": "A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas.", "content": "A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas. Epstein-Barr virus (EBV) infects cells in latent or lytic forms, but the role of lytic infection in EBV-induced lymphomas is unclear. Here, we have used a new humanized mouse model, in which both human fetal CD34(+) hematopoietic stem cells and thymus/liver tissue are transplanted, to compare EBV pathogenesis and lymphoma formation following infection with a lytic replication-defective BZLF1-deleted (Z-KO) virus or a lytically active BZLF1(+) control. Both the control and Z-KO viruses established long-term viral latency in all infected animals. The infection appeared well controlled in some animals, but others eventually developed CD20(+) diffuse large B cell lymphomas (DLBCL). Animals infected with the control virus developed tumors more frequently than Z-KO virus-infected animals. Specific immune responses against EBV-infected B cells were generated in mice infected with either the control virus or the Z-KO virus. In both cases, forms of viral latency (type I and type IIB) were observed that are less immunogenic than the highly transforming form (type III) commonly found in tumors of immunocompromised hosts, suggesting that immune pressure contributed to the outcome of the infection. These results point to an important role for lytic EBV infection in the development of B cell lymphomas in the context of an active host immune response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980506"}
{"pmid": "20980509", "title": "Reovirus infection or ectopic expression of outer capsid protein micro1 induces apoptosis independently of the cellular proapoptotic proteins Bax and Bak.", "content": "Reovirus infection or ectopic expression of outer capsid protein micro1 induces apoptosis independently of the cellular proapoptotic proteins Bax and Bak. Mammalian orthoreoviruses induce apoptosis in vivo and in vitro; however, the specific mechanism by which apoptosis is induced is not fully understood. Recent studies have indicated that the reovirus outer capsid protein μ1 is the primary determinant of reovirus-induced apoptosis. Ectopically expressed μ1 induces apoptosis and localizes to intracellular membranes. Here we report that ectopic expression of μ1 activated both the extrinsic and intrinsic apoptotic pathways with activation of initiator caspases-8 and -9 and downstream effector caspase-3. Activation of both pathways was required for μ1-induced apoptosis, as specific inhibition of either caspase-8 or caspase-9 abolished downstream effector caspase-3 activation. Similar to reovirus infection, ectopic expression of μ1 caused release into the cytosol of cytochrome c and smac/DIABLO from the mitochondrial intermembrane space. Pancaspase inhibitors did not prevent cytochrome c release from cells expressing μ1, indicating that caspases were not required. Additionally, μ1- or reovirus-induced release of cytochrome c occurred efficiently in Bax(-/-)Bak(-/-) mouse embryonic fibroblasts (MEFs). Finally, we found that reovirus-induced apoptosis occurred in Bax(-/-)Bak(-/-) MEFs, indicating that reovirus-induced apoptosis occurs independently of the proapoptotic Bcl-2 family members Bax and Bak.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980509"}
{"pmid": "20980508", "title": "Norovirus GII.4 strain antigenic variation.", "content": "Norovirus GII.4 strain antigenic variation. Noroviruses are the principal cause of epidemic gastroenteritis worldwide. Multiple reports have concluded that the major capsid proteins of GII.4 strains, which cause 80% of norovirus infections worldwide, are evolving rapidly, resulting in new epidemic strains. Surrogate neutralization assays using sera from outbreaks and from immunized mice suggest that, as with influenza virus, antigenic variation maintains GII.4 persistence in the face of human population herd immunity. To test this hypothesis, mice were hyperimmunized with virus-like particles (VLPs) representing an early (GII.4-1987) and a contemporary (GII.4-2006) GII.4 strain. Anti-GII.4-1987 IgG monoclonal antibodies (MAbs) strongly reacted with GII.4 VLPs derived between only 1987 and 2002. Ligand binding blockade was more efficient with GII.4-1987 and GII.4-1997 VLPs than with GII.4-2002. Anti-GII.4-2006 IgG MAbs recognized either a broad panel of GII.4 VLPs (1987 to 2006) or a subset of contemporary (2004 to 2006) VLPs. Most 2006 antibodies did not recognize or only poorly recognized GII.4 VLPs of 2007 or 2008, documenting rapid antigenic evolution of GII.4 capsids. Generally, 2006 MAbs blocked homotypic VLP-ligand binding but were unable to block VLPs representing strains primarily circulating during or earlier than 2002. These analyses demonstrate that both subtle and significant evolutionary change has occurred within antibody epitopes between epidemic strains, providing direct evidence that the GII.4 noroviruses are undergoing antigenic variation, likely in response to herd immunity. As with influenza virus, HIV, and hepatitis C virus, norovirus antigenic variation will significantly influence the design of efficacious vaccines and immunotherapeutics against these important human pathogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980508"}
{"pmid": "20980507", "title": "Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.", "content": "Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus. Newly emerging viruses often circulate as a heterogeneous swarm in wild animal reservoirs prior to their emergence in humans, and their antigenic identities are often unknown until an outbreak situation. The newly emerging severe acute respiratory syndrome coronavirus (SARS-CoV) and reemerging influenza virus cause disproportionate disease in the aged, who are also notoriously difficult to successfully vaccinate, likely due to immunosenescence. To protect against future emerging strains, vaccine platforms should induce broad cross-reactive immunity that is sufficient to protect from homologous and heterologous challenge in all ages. From initial studies, we hypothesized that attenuated Venezuelan equine encephalitis virus (VEE) replicon particle (VRP) vaccine glycoproteins mediated vaccine failure in the aged. We then compared the efficacies of vaccines bearing attenuated (VRP(3014)) or wild-type VEE glycoproteins (VRP(3000)) in young and aged mice within novel models of severe SARS-CoV pathogenesis. Aged animals receiving VRP(3000)-based vaccines were protected from SARS-CoV disease, while animals receiving the VRP(3014)-based vaccines were not. The superior protection for the aged observed with VRP(3000)-based vaccines was confirmed in a lethal influenza virus challenge model. While the VRP(3000) vaccine's immune responses in the aged were sufficient to protect against lethal homologous and heterologous challenge, our data suggest that innate defects within the VRP(3014) platform mediate vaccine failure. Exploration into the mechanism(s) of successful vaccination in the immunosenescent should aid in the development of successful vaccine strategies for other viral diseases disproportionately affecting the elderly, like West Nile virus, influenza virus, norovirus, or other emerging viruses of the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980507"}
{"pmid": "20980511", "title": "Dominant inhibition of Akt/protein kinase B signaling by the matrix protein of a negative-strand RNA virus.", "content": "Dominant inhibition of Akt/protein kinase B signaling by the matrix protein of a negative-strand RNA virus. Vesicular stomatitis virus (VSV) is a rhabdovirus that alters host nuclear and cytoplasmic function upon infection. We have investigated the effect of VSV infection on cellular signaling through the phosphatidylinositol-3 kinase (PI3k)/Akt signaling pathway. Akt phosphorylation at both threonine 308 (Thr308) and serine 473 (Ser473) was inhibited in cells infected with VSV. This inhibition was rapid (beginning within the first 2 to 3 h postinfection) and correlated with the dephosphorylation of downstream effectors of Akt, such as glycogen synthase kinase 3β (GSK3β) and mammalian target of rapamycin (mTOR). The dephosphorylation of Akt occurred in the presence of growth factor stimulation and was not overcome through constitutive membrane targeting of Akt or high levels of phosphatidylinositol-3,4,5-triphosphate (PIP3) accumulation in the membrane. Akt dephosphorylation was not a result of alterations in PDK1 phosphorylation or activity, changes in phosphatase and tensin homologue deleted on chromosome 10 (PTEN) levels, or the downregulation of PI3k signaling. Inactivation of Akt was caused by the expression of the viral M protein in the absence of other viral components, and an M protein mutant that does not inhibit RNA polymerase II (Pol II) transcription and nuclear/cytoplasmic transport was also defective in inhibiting Akt phosphorylation. These data illustrate that VSV utilizes a novel mechanism to alter this central player in cell signaling and oncogenesis. It also suggests an inside-out model of signal transduction where VSV interruption of nuclear events has a rapid and significant effect on membrane signaling events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980511"}
{"pmid": "20980510", "title": "Assembly and immunological properties of Newcastle disease virus-like particles containing the respiratory syncytial virus F and G proteins.", "content": "Assembly and immunological properties of Newcastle disease virus-like particles containing the respiratory syncytial virus F and G proteins. Human respiratory syncytial virus (RSV) is a serious respiratory pathogen in infants and young children as well as elderly and immunocompromised populations. However, no RSV vaccines are available. We have explored the potential of virus-like particles (VLPs) as an RSV vaccine candidate. VLPs composed entirely of RSV proteins were produced at levels inadequate for their preparation as immunogens. However, VLPs composed of the Newcastle disease virus (NDV) nucleocapsid and membrane proteins and chimera proteins containing the ectodomains of RSV F and G proteins fused to the transmembrane and cytoplasmic domains of NDV F and HN proteins, respectively, were quantitatively prepared from avian cells. Immunization of mice with these VLPs, without adjuvant, stimulated robust, anti-RSV F and G protein antibody responses. IgG2a/IgG1 ratios were very high, suggesting predominantly T(H)1 responses. In contrast to infectious RSV immunization, neutralization antibody titers were robust and stable for 4 months. Immunization with a single dose of VLPs resulted in the complete protection of mice from RSV replication in lungs. Upon RSV intranasal challenge of VLP-immunized mice, no enhanced lung pathology was observed, in contrast to the pathology observed in mice immunized with formalin-inactivated RSV. These results suggest that these VLPs are effective RSV vaccines in mice, in contrast to other nonreplicating RSV vaccine candidates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980510"}
{"pmid": "20980512", "title": "Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu.", "content": "Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu. The HIV-1 protein Vpu counteracts the antiviral activity of the innate restriction factor BST-2/tetherin by a mechanism that partly depends on its interaction with β-TrCP, a substrate adaptor for an SCF (Skp-Cullin 1-F box) E3 ubiquitin ligase complex. This suggests that Vpu stimulates the ubiquitination of BST-2 and that this underlies the relief of restriction. Here, we show that Vpu stimulates ubiquitination of BST-2. Mutation of all potential ubiquitination sites in the cytoplasmic domain of BST-2, including lysines, cysteines, serines, and threonines, abrogates Vpu-mediated ubiquitination. However, a serine-threonine-serine sequence specifically mediates the downregulation of BST-2 from the cell surface and the optimal relief of restricted virion release. Serine-threonine ubiquitination of BST-2 is likely part of the mechanism by which Vpu counteracts innate defenses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980512"}
{"pmid": "20980513", "title": "R5 HIV env and vesicular stomatitis virus G protein cooperate to mediate fusion to naive CD4+ T Cells.", "content": "R5 HIV env and vesicular stomatitis virus G protein cooperate to mediate fusion to naive CD4+ T Cells. Naïve CD4(4) T cells are resistant to both HIV R5 env and vesicular stomatitis virus G protein (VSV-G)-mediated fusion. However, viral particles carrying both HIV R5 env and VSV-G infect naïve cells by an unexplained mechanism. We show that VSV-G-pseudotyped virus cannot fuse to unstimulated cells because the viral particles cannot be endocytosed. However, virions carrying both HIV R5 env and VSV-G can fuse because CD4 binding allows viral uptake. Our findings reveal a unique mechanism by which R5 HIV env and VSV-G cooperate to allow entry to naïve CD4(+) T cells, providing a tool to target naïve CD4(+) T cells with R5 HIV to study HIV coreceptor signaling and latency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980513"}
{"pmid": "20980514", "title": "Domain structure of Lassa virus L protein.", "content": "Domain structure of Lassa virus L protein. The 200-kDa L protein of arenaviruses plays a central role in viral genome replication and transcription. This study aimed at providing evidence for the domain structure of L protein by combining bioinformatics with a stepwise mutagenesis approach using the Lassa virus minireplicon system. Potential interdomain linkers were predicted using various algorithms. The prediction was challenged by insertion of flexible sequences into the predicted linkers. Insertion of 5 or 10 amino acid residues was tolerated at seven sites (S407, G446, G467, G774, G939, S1952, and V2074 in Lassa virus AV). At two of these sites, G467 and G939, L protein could be split into an N-terminal and a C-terminal part, which were able to trans-complement each other and reconstitute a functional complex upon coexpression. Coimmunoprecipitation studies revealed physical interaction between the N- and C-terminal domains, irrespective of whether L protein was split at G467 or G939. In confocal immunofluorescence microscopy, the N-terminal domains showed a dot-like, sometimes perinuclear, cytoplasmic distribution similar to that of full-length L protein, while the C-terminal domains were homogenously distributed in cytoplasm. The latter were redistributed into the dot-like structures upon coexpression with the corresponding N-terminal domain. In conclusion, this study demonstrates two interdomain linkers in Lassa virus L protein, at G467 and G939, suggesting that L protein is composed of at least three structural domains spanning residues 1 to 467, 467 to 939, and 939 to 2220. The first domain seems to mediate accumulation of L protein into cytoplasmic dot-like structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980514"}
{"pmid": "20980515", "title": "Reverse genetics generation of chimeric infectious Junin/Lassa virus is dependent on interaction of homologous glycoprotein stable signal peptide and G2 cytoplasmic domains.", "content": "Reverse genetics generation of chimeric infectious Junin/Lassa virus is dependent on interaction of homologous glycoprotein stable signal peptide and G2 cytoplasmic domains. The Arenaviridae are a diverse and globally distributed collection of viruses that are maintained primarily by rodent reservoirs. Junin virus (JUNV) and Lassa virus (LASV) can both cause significant outbreaks of severe and often fatal human disease throughout their respective areas of endemicity. In an effort to improve upon the existing live attenuated JUNV Candid1 vaccine, we generated a genetically homogenous stock of this virus from cDNA copies of the virus S and L segments by using a reverse genetics system. Further, these cDNAs were used in combination with LASV cDNAs to successfully generate two recombinant Candid1 JUNV/LASV chimeric viruses (via envelope glycoprotein [GPC] exchange). It was found that while the GPC extravirion domains were readily exchangeable, homologous stable signal peptide (SSP) and G2 transmembrane and cytoplasmic tail domains were essential for correct GPC maturation and production of infectious chimeric viruses. The switching of the JUNV and LASV G1/G2 ectodomains within the Candid1 vaccine background did not alter the attenuated phenotype of the vaccine strain in a lethal mouse model. These recombinant chimeric viruses shed light on the fundamental requirements of arenavirus GPC maturation and may serve as a strategy for the development of bivalent JUNV and LASV vaccine candidates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980515"}
{"pmid": "20980516", "title": "B7-mediated costimulation of CD4 T cells constrains cytomegalovirus persistence.", "content": "B7-mediated costimulation of CD4 T cells constrains cytomegalovirus persistence. Cytomegalovirus (CMV) utilizes multiple strategies to modulate immunity and promote lifelong, persistent/latent infection, including suppressing T cell activation pathways. Here we examined the role of B7 costimulatory ligands in establishing immune détente from both the host and virus perspectives. Mice lacking both B7.1 and B7.2 showed reduced early expansion of CMV-specific CD4 T cells, consequently allowing for enhanced levels of persistent virus replication. In turn, a CMV mutant lacking expression of the m138 and m147.5 gene products, which restrict B7.1 and B7.2 expression in infected antigen-presenting cells, induced a more robust CD4 T cell response and showed decreased persistence. Together, these data reveal a requirement for B7-mediated signaling in regulating the CMV-specific CD4 T cell response and establishing host-virus equilibrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980516"}
{"pmid": "20980518", "title": "Upregulation of CXCL10 in human dorsal root ganglia during experimental and natural varicella-zoster virus infection.", "content": "Upregulation of CXCL10 in human dorsal root ganglia during experimental and natural varicella-zoster virus infection. Varicella-zoster virus (VZV) reactivation causes herpes zoster, which is accompanied by an influx of lymphocytes into affected ganglia, but the stimulus for this infiltrate is not known. We report that VZV infection of ganglia leads to increased CXCL10 production in vitro, in an explant ganglion model and in naturally infected dorsal root ganglia (DRG) during herpes zoster. Lymphocytes expressing the receptor for CXCL10, CXCR3, were also observed throughout naturally infected ganglia during herpes zoster, including immediately adjacent to neurons. This study identifies VZV-induced CXCL10 as a potential driver of T lymphocyte recruitment into DRG during herpes zoster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980518"}
{"pmid": "20980517", "title": "A recombinant measles virus unable to antagonize STAT1 function cannot control inflammation and is attenuated in rhesus monkeys.", "content": "A recombinant measles virus unable to antagonize STAT1 function cannot control inflammation and is attenuated in rhesus monkeys. Measles remains a leading cause of death worldwide among children because it suppresses immune function. The measles virus (MV) P gene encodes three proteins (P, V, and C) that interfere with innate immunity, controlling STAT1, STAT2, mda5, and perhaps other key regulators of immune function. We identified here three residues in the shared domain of the P and V proteins-tyrosine 110, valine 112, and histidine 115-that function to retain STAT1 in the cytoplasm and inhibit interferon transcription. This information was used to generate a recombinant measles virus unable to antagonize STAT1 function (STAT1-blind MV) differing only in these three residues from a wild-type strain of well-defined virulence. This virus was used to assess the relevance of P and V interactions with STAT1 for virulence in primates. When a group of six rhesus monkeys (Macaca mulatta) was inoculated intranasally with STAT1-blind MV, viremia was short-lived, and the skin rash and other clinical signs observed with wild-type MV were absent. The STAT1-blind virus less efficiently controlled the inflammatory response, as measured by enhanced transcription of interleukin-6 and tumor necrosis factor alpha in peripheral blood mononuclear cells from infected hosts. Importantly, neutralizing antibody titers and MV-specific T-cell responses were equivalent in hosts infected with either virus. These findings indicate that efficient MV interactions with STAT1 are required to sustain virulence in a natural host by controlling the inflammatory response against the virus. They also suggest that selectively STAT1-blind MV may have utility as vectors for targeted oncolysis and vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980517"}
{"pmid": "20980520", "title": "Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.", "content": "Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor. Rfv3 is an autosomal dominant gene that influences the recovery of resistant mice from Friend retrovirus (FV) infection by limiting viremia and promoting a more potent neutralizing antibody response. We previously reported that Rfv3 is encoded by Apobec3, an innate retrovirus restriction factor. However, it was recently suggested that the Rfv3 susceptible phenotype of high viremia at 28 days postinfection (dpi) was more dominantly controlled by the B-cell-activating factor receptor (BAFF-R), a gene that is linked to but located outside the genetically mapped region containing Rfv3. Although one prototypical Rfv3 susceptible mouse strain, A/WySn, indeed contains a dysfunctional BAFF-R, two other Rfv3 susceptible strains, BALB/c and A.BY, express functional BAFF-R genes, determined on the basis of genotyping and B-cell immunophenotyping. Furthermore, transcomplementation studies in (C57BL/6 [B6] × BALB/c)F(1) and (B6 × A.BY)F(1) mice revealed that the B6 Apobec3 gene significantly influences recovery from FV viremia, cellular infection, and disease at 28 dpi. Finally, the Rfv3 phenotypes of prototypic B6, A.BY, A/WySn, and BALB/c mouse strains correlate with reported Apobec3 mRNA expression levels. Overall, these findings argue against the generality of BAFF-R polymorphisms as a dominant mechanism to explain the Rfv3 recovery phenotype and further strengthen the evidence that Apobec3 encodes Rfv3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980520"}
{"pmid": "20980519", "title": "Activation of plasmacytoid dendritic cells by Kaposi's sarcoma-associated herpesvirus.", "content": "Activation of plasmacytoid dendritic cells by Kaposi's sarcoma-associated herpesvirus. Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with multiple human malignancies, including Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Following primary infection, KSHV typically goes through a brief period of lytic replication prior to the establishment of latency. Plasmacytoid dendritic cells (pDCs) are the major producers of type 1 interferon (IFN), primarily in response to virus infection. Toll-like receptors (TLRs) are key components of the innate immune system, and they serve as pathogen recognition receptors that stimulate the host antiviral response. pDCs express exclusively TLR7 and TLR9, and it is through these TLRs that the type 1 interferon response is activated in pDCs. Currently, it is not known whether KSHV is recognized by pDCs and whether activation of pDCs occurs in response to KSHV infection. We now report evidence that KSHV can infect human pDCs and that pDCs are activated upon KSHV infection, as measured by upregulation of CD83 and CD86 and by IFN-α secretion. We further show that induction of IFN-α occurs through activation of TLR9 signaling and that a TLR9 inhibitor diminishes the production and secretion of IFN-α by KSHV-infected pDCs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980519"}
{"pmid": "20980522", "title": "RNA aptamers directed to human immunodeficiency virus type 1 Gag polyprotein bind to the matrix and nucleocapsid domains and inhibit virus production.", "content": "RNA aptamers directed to human immunodeficiency virus type 1 Gag polyprotein bind to the matrix and nucleocapsid domains and inhibit virus production. Gag orchestrates the assembly and release of human immunodeficiency virus type 1 (HIV-1) particles. We explored here the potential of anti-Gag RNA aptamers to inhibit HIV-1 replication. In vitro, RNA aptamers raised against an HIV-1 Gag protein, lacking the N-terminal myristate and the C-terminal p6 (DP6-Gag), could bind to matrix protein (MA), nucleocapsid protein (NC), or entire DP6-Gag protein. Upon cotransfection with pNL4-3.Luc molecular clone into 293T cells, six of the aptamers caused mild inhibition (2- to 3-fold) in the extracellular capsid levels, and one aptamer displayed 20-fold inhibition. The reduction was not due to a release defect but reflected Gag mRNA levels. We hypothesized that the aptamers influence genomic RNA levels via perturbation of specific Gag-genomic RNA interactions. Binding studies revealed that the \"NC-binders\" specifically compete with the packaging signal (ψ) of HIV-1 for binding to DP6-Gag. Therefore, we tested the ability of two NC-binders to inhibit viruses containing ψ-region deletions (ΔSL1 or ΔSL3) and found that the NC-binders were no longer able to inhibit Gag synthesis. The inability of these aptamers to inhibit ψ-deleted viruses correlated with the absence of competition with the corresponding ψ transcripts lacking SL1 or SL3 for binding DP6-Gag in vitro. These results indicate that the NC-binding aptamers disrupt Gag-genomic RNA interaction and negatively affect genomic RNA transcription, processing, or stability. Our results reveal an essential interaction between HIV-1 Gag and the ψ-region that may be distinct from that which occurs during the encapsidation of genomic RNA. Thus, anti-Gag aptamers can be an effective tool to perturb Gag-genomic RNA interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980522"}
{"pmid": "20980521", "title": "Characterization of cross-reactive CD8+ T-cell recognition of HLA-A2-restricted HIV-Gag (SLYNTVATL) and HCV-NS5b (ALYDVVSKL) epitopes in individuals infected with human immunodeficiency and hepatitis C viruses.", "content": "Characterization of cross-reactive CD8+ T-cell recognition of HLA-A2-restricted HIV-Gag (SLYNTVATL) and HCV-NS5b (ALYDVVSKL) epitopes in individuals infected with human immunodeficiency and hepatitis C viruses. The immunologic mechanisms underlying the faster progression of hepatitis C virus (HCV) disease in the presence of human immunodeficiency virus (HIV) coinfection are not clearly understood. T-cell cross-reactivity between HCV and influenza virus-specific epitopes has been associated with rapid progression of HCV disease (S. Urbani, B. Amadei, P. Fisicaro, M. Pilli, G. Missale, A. Bertoletti, and C. Ferrari, J. Exp. Med. 201:675-680, 2005). We asked whether T-cell cross-reactivity between HCV and HIV could exist during HCV/HIV coinfection and affect pathogenesis. Our search for amino acid sequence homology between the HCV and HIV proteomes revealed two similar HLA-A2-restricted epitopes, HIV-Gag (SLYNTVATL [HIV-SL9]) and HCV-NS5b (ALYDVVSKL [HCV-AL9]). We found that 4 out of 20 HLA-A2-positive (HLA-A2(+)) HIV-infected individuals had CD8(+) T cells that recognized both the HIV-SL9 and HCV-AL9 epitopes. However, the AL9 epitope was generally shown to be a weak agonist. Although HCV-monoinfected individuals in our study did not show AL9-specific responses, we found that about half of HCV/HIV-coinfected individuals had dual responses to both epitopes. High dual T-cell recognition among coinfected subjects was usually due to separate T-cell populations targeting each epitope, as determined by pentamer staining. The one individual demonstrating cross-reactive T cells to both epitopes showed the most advanced degree of liver disease. In coinfected individuals, we observed a positive correlation between the magnitudes of T-cell responses to both the SL9 and the AL9 epitopes, which was also positively associated with the clinical parameter of liver damage. Thus, we find that HIV infection induces T cells that can cross-react to heterologous viruses or prime for T cells that are closely related in sequence. However, the induction of cross-reactive T cells may not be associated with control of disease caused by the heterologous virus. This demonstrates that degeneracy of HIV-specific T cells may play a role in the immunopathology of HCV/HIV coinfection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980521"}
{"pmid": "20980524", "title": "Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection.", "content": "Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection. Type 1 interferons (IFNs) induce the expression of the tripartite interaction motif (TRIM) family of E3 ligases, but the contribution of these antiviral factors to HIV pathogenesis is not completely understood. We hypothesized that the increased expression of select type 1 IFN and TRIM isoforms is associated with a significantly lower likelihood of HIV-1 acquisition and viral control during primary HIV-1 infection. We measured IFN-α, IFN-β, myxovirus resistance protein A (MxA), human TRIM5α (huTRIM5α), and TRIM22 mRNA levels in peripheral blood mononuclear cells (PBMCs) of high-risk, HIV-1-uninfected participants and HIV-1-positive study participants. Samples were available for 32 uninfected subjects and 28 infected persons, all within 1 year of infection. HIV-1-positive participants had higher levels of IFN-β (P = 0.0005), MxA (P = 0.007), and TRIM22 (P = 0.01) and lower levels of huTRIM5α (P < 0.001) than did HIV-1-negative participants. TRIM22 but not huTRIM5α correlated positively with type 1 IFN (IFN-α, IFN-β, and MxA) (all P < 0.0001). In a multivariate model, increased MxA expression showed a significant positive association with viral load (P = 0.0418). Furthermore, TRIM22 but not huTRIM5α, IFN-α, IFN-β, or MxA showed a negative correlation with plasma viral load (P = 0.0307) and a positive correlation with CD4(+) T-cell counts (P = 0.0281). In vitro studies revealed that HIV infection induced TRIM22 expression in PBMCs obtained from HIV-negative donors. Stable TRIM22 knockdown resulted in increased HIV-1 particle release and replication in Jurkat reporter cells. Collectively, these data suggest concordance between type 1 IFN and TRIM22 but not huTRIM5α expression in PBMCs and that TRIM22 likely acts as an antiviral effector in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980524"}
{"pmid": "20980523", "title": "T cell-mediated protection against lethal 2009 pandemic H1N1 influenza virus infection in a mouse model.", "content": "T cell-mediated protection against lethal 2009 pandemic H1N1 influenza virus infection in a mouse model. Genetic mutation and reassortment of influenza virus gene segments, in particular those of hemagglutinin (HA) and neuraminidase (NA), that lead to antigenic drift and shift are the major strategies for influenza virus to escape preexisting immunity. The most recent example of such phenomena is the first pandemic of H1N1 influenza of the 21st century, which started in 2009. Cross-reactive antibodies raised against H1N1 viruses circulating before 1930 show protective activity against the 2009 pandemic virus. Cross-reactive T-cell responses can also contribute to protection, but in vivo support of this view is lacking. To explore the protection mechanisms in vivo, we primed mice with H1 and H3 influenza virus isolates and rechallenged them with a virus derived from the 2009 H1N1 A/CA/04/09 virus, named CA/E3/09. We found that priming with influenza viruses of both H1 and H3 homo- and heterosubtypes protected against lethal CA/E3/09 virus challenge. Convalescent-phase sera from these primed mice conferred no neutralization activity in vitro and no protection in vivo. However, T-cell depletion studies suggested that both CD4 and CD8 T cells contributed to the protection. Taken together, these results indicate that cross-reactive T cells established after initial priming with distally related viruses can be a vital component for prevention of disease and control of pandemic H1N1 influenza virus infection. Our results highlight the importance of establishing cross-reactive T-cell responses for protecting against existing or newly emerging pandemic influenza viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980523"}
{"pmid": "20980527", "title": "Thermal transition of native tobacco mosaic virus and RNA-free viral proteins into spherical nanoparticles.", "content": "Thermal transition of native tobacco mosaic virus and RNA-free viral proteins into spherical nanoparticles. Spherical nanoparticles (SNPs) were generated by two-step thermal remodelling of native tobacco mosaic virus (TMV) at 94 °C. Particles of irregular shape and varying size were generated by TMV at 90 °C. They could be converted into SNPs by heating at 94 °C and were considered to be intermediate precursors of SNPs. In addition to SNP monomers (53 nm diameter), generated by individual TMV virions, large SNPs (100-800 nm diameter) were assembled. The size of the SNPs depended on the TMV concentration. The SNPs could be generated by distinct forms of RNA-free TMV coat protein (CP) aggregates and individual CP subunits. A one-step SNP assembly appeared to occur in these cases. These results show that SNPs represent a new type of particle nanoplatform for producing compositions of SNPs with foreign protein molecules bound to their surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980527"}
{"pmid": "20980525", "title": "Determinants that specify the integration pattern of retrotransposon Tf1 in the fbp1 promoter of Schizosaccharomyces pombe.", "content": "Determinants that specify the integration pattern of retrotransposon Tf1 in the fbp1 promoter of Schizosaccharomyces pombe. Long terminal repeat (LTR) retrotransposons are closely related to retroviruses and, as such, are important models for the study of viral integration and target site selection. The transposon Tf1 of Schizosaccharomyces pombe integrates with a strong preference for the promoters of polymerase II (Pol II)-transcribed genes. Previous work in vivo with plasmid-based targets revealed that the patterns of insertion were promoter specific and highly reproducible. To determine which features of promoters are recognized by Tf1, we studied integration in a promoter that has been characterized. The promoter of fbp1 has two upstream activating sequences, UAS1 and UAS2. We found that integration was targeted to two windows, one 180 nucleotides (nt) upstream and the other 30 to 40 nt downstream of UAS1. A series of deletions in the promoter showed that the integration activities of these two regions functioned autonomously. Integration assays of UAS2 and of a synthetic promoter demonstrated that strong promoter activity alone was not sufficient to direct integration. The factors that modulate the transcription activities of UAS1 and UAS2 include the activators Atf1p, Pcr1p, and Rst2p as well as the repressors Tup11p, Tup12p, and Pka1p. Strains lacking each of these proteins revealed that Atf1p alone mediated the sites of integration. These data indicate that Atf1p plays a direct and specific role in targeting integration in the promoter of fbp1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980525"}
{"pmid": "20980526", "title": "An in-depth analysis of original antigenic sin in dengue virus infection.", "content": "An in-depth analysis of original antigenic sin in dengue virus infection. The evolution of dengue viruses has resulted in four antigenically similar yet distinct serotypes. Infection with one serotype likely elicits lifelong immunity to that serotype, but generally not against the other three. Secondary or sequential infections are common, as multiple viral serotypes frequently cocirculate. Dengue infection, although frequently mild, can lead to dengue hemorrhagic fever (DHF) which can be life threatening. DHF is more common in secondary dengue infections, implying a role for the adaptive immune response in the disease. There is currently much effort toward the design and implementation of a dengue vaccine but these efforts are made more difficult by the challenge of inducing durable neutralizing immunity to all four viruses. Domain 3 of the dengue virus envelope protein (ED3) has been suggested as one such candidate because it contains neutralizing epitopes and it was originally thought that relatively few cross-reactive antibodies are directed to this domain. In this study, we performed a detailed analysis of the anti-ED3 response in a cohort of patients suffering either primary or secondary dengue infections. The results show dramatic evidence of original antigenic sin in secondary infections both in terms of binding and enhancement activity. This has important implications for dengue vaccine design because heterologous boosting is likely to maintain the immunological footprint of the first vaccination. On the basis of these findings, we propose a simple in vitro enzyme-linked immunosorbent assay (ELISA) to diagnose the original dengue infection in secondary dengue cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980526"}
{"pmid": "20980530", "title": "Ocular adnexal marginal zone B cell lymphoma infiltrated by IgG4-positive plasma cells.", "content": "Ocular adnexal marginal zone B cell lymphoma infiltrated by IgG4-positive plasma cells. To report the clinicopathological characteristics of patients with ocular adnexal marginal zone B cell lymphoma (MZBL) with IgG4-positive plasma cells. 114 biopsy samples of ocular adnexal MZBLs were analysed. MZBLs with IgG4-positive plasma cells were included when the IgG4:IgG ratio was >40% (IgG4-related group). The serum levels of each subclass of immunoglobulins and soluble interleukin-2 receptor in the IgG4-related group were compared with those in 61 consecutive patients having MZBL without IgG4-positive plasma cells (IgG4-unrelated group). They were also compared with those in 10 patients having ocular adnexal IgG4-related lymphoplasmacytic disorder (IgG4-related inflammatory group). Ten (9%) of the patients were diagnosed with MZBL with IgG4-positive plasma cells. The IgG4-related group had a significantly greater degree of sclerosis and reactive follicles in the MZBLs (p=0.0004 and p=0.01, respectively). The serum levels of IgG, IgG1, IgG4, IgE and soluble interleukin 2 receptor in the IgG4-related group were significantly higher than those in the IgG4-unrelated group (p=0.003, p=0.009, p<0.0001, p<0.0001 and p=0.0007, respectively). The serum levels did not differ significantly from those of the IgG4-related inflammatory group. The IgG4-related group also had reactive IgG4-positive lymphoplasmacytic infiltrations in the recurrent lesion and in the stomach. IgG4-positive plasma cells had infiltrated into ocular adnexal MZBLs in 9% of cases. It is suggested that ocular adnexal MZBLs with IgG4-positive plasma cells have unique histological and serological characteristics that overlap those of ocular adnexal IgG4-related lymphoplasmacytic infiltrative disorder and systemic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980530"}
{"pmid": "20980531", "title": "The expression of EMP1 is downregulated in oral squamous cell carcinoma and possibly associated with tumour metastasis.", "content": "The expression of EMP1 is downregulated in oral squamous cell carcinoma and possibly associated with tumour metastasis. To investigate the expression of EMP1 in oral squamous cell carcinoma (OSCC) tissues and its correlation with available clinical parameters of patients with OSCC. The mRNA levels of EMP1 were measured in 18 paired OSCC and corresponding adjacent normal tissues using RT-PCR. Another 45 pairs of OSCC samples were selected to detect the mRNA level of EMP1 using quantitative RT-PCR (qRT-PCR). The protein levels of EMP1 were also evaluated in 60 cases of patients with OSCC using immunohistochemical staining. The correlation between EMP1 expression and clinical parameters was analysed with non-parametric analysis. The results of RT-PCR and qRT-PCR showed that, compared with the paired normal tissues, the mRNA levels of EMP1 were significantly decreased in OSCC. The immunohistochemical results indicated that the EMP1 protein was also downregulated in OSCC (p=0.031). Decreased expression of EMP1 was significantly correlated with clinical stage (p=0.002) and lymph node metastasis (p=0.044) of patients with OSCC. Meanwhile, there was a significant difference between OSCCs at early and advanced stages (p=0.003), and between OSCCs with lymph node metastasis and no lymph node metastasis (p=0.045), respectively. The results suggest that EMP1 may be a tumour suppressor and associated with lymph node metastasis in OSCC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980531"}
{"pmid": "20980529", "title": "Intra-host diversities of the receptor-binding domain of stork faeces-derived avian H5N1 viruses and its significance as predicted by molecular dynamic simulation.", "content": "Intra-host diversities of the receptor-binding domain of stork faeces-derived avian H5N1 viruses and its significance as predicted by molecular dynamic simulation. Virus evolution facilitates the emergence of viruses with unpredictable impacts on human health. This study investigated intra-host variations of the receptor-binding domain (RBD) of the haemagglutinin (HA) gene of the avian H5N1 viruses obtained from the 2004 and 2005 epidemics. The results showed that the mutation frequency of the RBD ranged from 0.3 to 0.6 %. The mutations generated one consensus and several minor populations. The consensus population of the 2004 epidemic was transmitted to the 2005 outbreak with increased frequency (39 and 45 %, respectively). Molecular dynamics simulation was applied to predict the significance of the variants. The results revealed that the consensus sequence (E218K/V248I) interacted unstably with sialic acid (SA) with an α2,6 linkage (SAα2,6Gal). Although the mutated K140R/E218K/V248I and Y191C/E218K/V248I sequences decreased the HA binding capacity to α2,3-linked SA, they were shown to bind α2,6-linked SA with increased affinity. Moreover, the substitutions at aa 140 and 191 were positive-selection sites. These data suggest that the K140R and Y191C mutations may represent a step towards human adaptation of the avian H5N1 virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980529"}
{"pmid": "20980528", "title": "X-box binding protein 1 induces the expression of the lytic cycle transactivator of Kaposi's sarcoma-associated herpesvirus but not Epstein-Barr virus in co-infected primary effusion lymphoma.", "content": "X-box binding protein 1 induces the expression of the lytic cycle transactivator of Kaposi's sarcoma-associated herpesvirus but not Epstein-Barr virus in co-infected primary effusion lymphoma. Cells of primary effusion lymphoma (PEL), a B-cell non-Hodgkin's lymphoma, are latently infected by Kaposi's sarcoma-associated herpesvirus (KSHV), with about 80 % of PEL also co-infected with Epstein-Barr virus (EBV). Both viruses can be reactivated into their lytic replication cycle in PEL by chemical inducers. However, simultaneous activation of both lytic cascades leads to mutual lytic cycle co-repression. The plasma cell-differentiation factor X-box binding protein 1 (XBP-1) transactivates the KSHV immediate-early promoter leading to the production of the replication and transcription activator protein (RTA), and reactivation of KSHV from latency. XBP-1 has been reported to act similarly on the EBV immediate-early promoter Zp, leading to the production of the lytic-cycle transactivator protein BZLF1. Here we show that activated B-cell terminal-differentiation transcription factor X-box binding protein 1 (XBP-1s) does not induce EBV BZLF1 and BRLF1 expression in PEL and BL cell lines, despite inducing lytic reactivation of KSHV in PEL. We show that XBP-1s transactivates the KSHV RTA promoter but does not transactivate the EBV BZLF1 promoter in non-B-cells by using a luciferase assay. Co-expression of activated protein kinase D, which can phosphorylate and inactivate class II histone deacetylases (HDACs), does not rescue XBP-1 activity on Zp nor does it induce BZLF1 and BRLF1 expression in PEL. Finally, chemical inducers of KSHV and EBV lytic replication in PEL, including HDAC inhibitors, do not lead to XBP-1 activation. We conclude that XBP-1 specifically reactivates the KSHV lytic cycle in dually infected PELs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980528"}
{"pmid": "20980532", "title": "Uveal melanoma metastasising to the heart after 39 years.", "content": "Uveal melanoma metastasising to the heart after 39 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980532"}
{"pmid": "20980533", "title": "Voices from the inside: African American women's perspectives on healthy lifestyles.", "content": "Voices from the inside: African American women's perspectives on healthy lifestyles. The author of this study conducted focus groups with African American women to explore their perspectives on obesity, disease causation, and their ideas on the functionality of cultural, social, historical, environmental, and psychological forces in altering healthy eating habits. Reoccurring themes centered on four areas: (a) the definition of health as a mind, body, and spiritual construct; (b) conceptualizations of cultural norms regarding healthy foods versus unhealthy foods; (c) the importance of eating and social rituals on food choices; and (d) the impact of the environment in sustaining healthy initiatives. Structural constraints that uphold legacies of disenfranchisement, environmental injustice, and segregation influence the food choices available in low-wealth communities. These factors continue to operate and are vital issues to consider when designing culturally relevant wellness programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980533"}
{"pmid": "20980534", "title": "Exploring the influence of a social ecological model on school-based physical activity.", "content": "Exploring the influence of a social ecological model on school-based physical activity. Among rising rates of overweight and obesity, schools have become essential settings to promote health behaviors, such as physical activity (PA). As schools exist within a broader environment, the social ecological model (SEM) provided a framework to consider how different levels interact and influence PA. The purpose of this study was to provide insight on school-based PA promotion by investigating the integration between different levels of Emmons's SEM within one public school board in a large Canadian city. Interviews were conducted with participants from the government (n = 4), the public school board (n = 3), principals (n = 3), and teachers (n = 4) and analyzed to explore perspectives on the various levels of the model. The results suggested that higher level policies \"trickled down\" into the organizational level of the SEM but there was pivotal responsibility for schools to determine how to implement PA strategies. Furthermore, schools have difficulty implementing PA because of the continued priority of academic achievement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980534"}
{"pmid": "20980535", "title": "A comparison of the effectiveness of a telephone coaching program and a mail-based program.", "content": "A comparison of the effectiveness of a telephone coaching program and a mail-based program. Many health promotion interventions have been developed and tested in recent years. Practitioners and researchers must continue to explore how various program delivery modalities can be used effectively and efficiently to optimize program outcomes. A sample of 6,055 participants was drawn from 10 large employers. Participants self-selected into a mail or telephone intervention. This study compared the demographics of those who selected each modality and assessed differences in program success relative to the modalities chosen. Telephone participants were more likely to be older, female, and salaried. Telephone participants were also more ready, confident, and motivated to make a behavior change, when compared to those in the mail program. Researchers found both the telephone and mail programs to be effective in reducing participants' health risk status, though the telephone program was slightly more effective. These findings demonstrate the importance of offering a variety of interventions when promoting healthy changes. More research is needed to investigate the role of participant choice and the combinations of learning experiences that best facilitate sustainable behavior change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980535"}
{"pmid": "20980536", "title": "Prevalence and psychosocial correlates of current smoking among adolescent students in Thailand, 2005.", "content": "Prevalence and psychosocial correlates of current smoking among adolescent students in Thailand, 2005. This article examines the prevalence of current smoking and associated psychosocial correlates and whether these correlates differ by sex among adolescent students in Thailand. Data were analyzed from the Thailand Global Youth Tobacco Survey (GYTS), a school-based, cross-sectional survey conducted in 2005 and completed by Mathayom 1, 2, and 3 (U.S. seventh through ninth grades) students. Weighted prevalence estimates of the percentage of students who were current smokers (smoked on ≥ 1 day during the past 30 days) and noncurrent smokers were calculated for the sample and for each psychosocial variable. Separate logistic regression models were calculated for males and females to examine the independent association of the psychosocial correlates of current smoking. Significant correlates for both males and females included close peer smoking, secondhand smoke exposure, being offered a free cigarette by a tobacco industry representative, and belief that smoking is not harmful. These correlates are examined in the context of comprehensive tobacco control laws in Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980536"}
{"pmid": "20980538", "title": "TNFα mechanically sensitizes masseter muscle nociceptors by increasing prostaglandin E2 levels.", "content": "TNFα mechanically sensitizes masseter muscle nociceptors by increasing prostaglandin E2 levels. TNFα induces mechanical sensitization of rat masseter muscle nociceptors, which takes 2-3 h to manifest and is mediated through activation of P55 and P75 receptors. This study was undertaken to determine whether TNFα induces nociceptor mechanical sensitization through the release of other algogenic substances such as glutamate, prostaglandin E(2) (PGE(2)), and/or nerve growth factor (NGF), which have been shown to induce mechanical sensitization of muscle nociceptors. Masseter muscle homogenate levels of PGE(2) and NGF were measured 3 h after injection of TNFα (1 μg) or vehicle control using commercially available kits. Interstitial glutamate concentration was measured after injection of TNFα or vehicle control using a glutamate-selective biosensor probe. Diclofenac, a cyclooxygenase inhibitor that blocks the synthesis of PGE(2), D-2-amino-5-phosphonovaleric acid (APV), a competitive N-methyl-D-aspartate (NMDA) receptor antagonist, and a tyrosine kinase A (TrkA) receptor antibody, which blocks NGF-induced masseter muscle nociceptor sensitization, were used to assess the contribution of PGE(2), glutamate, and NGF to TNFα-induced nociceptor sensitization. PGE(2) and glutamate concentrations were significantly elevated 3 h after TNFα injection into the masseter muscle. Injection of diclofenac partially reversed the TNFα-induced decreases in the mechanical threshold (MT) of masseter muscle nociceptors, whereas vehicle control, APV, and TrkA antibody did not significantly alter nociceptor MT. These results suggest that TNFα-induced mechanical sensitization of masseter muscle nociceptors is mediated in part by increased PGE(2) levels. The findings of this study support the hypothesis that TNFα induces a delayed mechanical sensitization of masseter muscle nociceptors indirectly by the release of PGE(2).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980538"}
{"pmid": "20980537", "title": "Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity.", "content": "Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity. Immediately after spinal cord injury (SCI), a devastating paralysis results from the loss of brain stem and cortical innervation of spinal neurons that control movement, including a loss of serotonergic (5-HT) innervation of motoneurons. Over time, motoneurons recover from denervation and function autonomously, exhibiting large persistent calcium currents (Ca PICs) that both help with functional recovery and contribute to uncontrolled muscle spasms. Here we systematically evaluated which 5-HT receptor subtypes influence PICs and spasms after injury. Spasms were quantified by recording the long-lasting reflexes (LLRs) on ventral roots in response to dorsal root stimulation, in the chronic spinal rat, in vitro. Ca PICs were quantified by intracellular recording in synaptically isolated motoneurons. Application of agonists selective to 5-HT(2B) and 5-HT(2C) receptors (including BW723C86) significantly increased the LLRs and associated Ca PICs, whereas application of agonists to 5-HT(1), 5-HT(2A), 5-HT(3), or 5-HT(4/5/6/7) receptors (e.g., 8-OH-DPAT) did not. The 5-HT(2) receptor agonist-induced increases in LLRs were dose dependent, with doses for 50% effects (EC(50)) highly correlated with published doses for agonist receptor binding (K(i)) at 5-HT(2B) and 5-HT(2C) receptors. Application of selective antagonists to 5-HT(2B) (e.g., RS127445) and 5-HT(2C) (SB242084) receptors inhibited the agonist-induced increase in LLR. However, antagonists that are known to specifically be neutral antagonists at 5-HT(2B/C) receptors (e.g., RS127445) had no effect when given by themselves, indicating that these receptors were not activated by residual 5-HT in the spinal cord. In contrast, inverse agonists (such as SB206553) that block constitutive activity at 5-HT(2B) or 5-HT(2C) receptors markedly reduced the LLRs, indicating the presence of constitutive activity in these receptors. 5-HT(2B) or 5-HT(2C) receptors were confirmed to be on motoneurons by immunolabeling. In summary, 5-HT(2B) and 5-HT(2C) receptors on motoneurons become constitutively active after injury and ultimately contribute to recovery of motoneuron function and emergence of spasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980537"}
{"pmid": "20980540", "title": "Local-distributed integration by a novel neuron ensures rapid initiation of animal locomotion.", "content": "Local-distributed integration by a novel neuron ensures rapid initiation of animal locomotion. Animals are adapted to respond quickly to threats in their environment. In many invertebrate and some vertebrate species, the evolutionary pressures have resulted in rapidly conducting giant axons, which allow short response times. Although neural circuits mediating escape behavior are identified in several species, little attention has been paid to this behavior in the medicinal leech, a model organism whose neuronal circuits are well known. We present data that suggest an alternative to giant axons for the rapid initiation of locomotion. A novel individual neuron, cell E21, appears to be one mediator of this short-latency action in the leech. In isolated nerve cord and semi-intact preparations, cell E21 excitation initiates and extends swimming and reduces the cycle period. The soma of this cell is located caudally, but its axon extends nearly the entire length of the nerve cord. We found that cell E21 fires impulses following local sensory inputs anywhere along the body and makes excitatory synapses onto the gating cells that drive swimming behavior. These distributed input-output sites minimize the distance information travels to initiate swimming behavior, thus minimizing the latency between sensory input and motor output. We propose that this single cell E21 functions to rapidly initiate or modulate locomotion through its distributed synaptic connections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980540"}
{"pmid": "20980539", "title": "Dynamic regulation of NMDA receptor transmission.", "content": "Dynamic regulation of NMDA receptor transmission. N-methyl-D-aspartate receptors (NMDARs) are critical for establishing, maintaining, and modifying glutamatergic synapses in an activity-dependent manner. The subunit composition, synaptic expression, and some of the properties of NMDARs are regulated by synaptic activity, affecting processes like synaptic plasticity. NMDAR transmission is dynamic, and we were interested in studying the effect of acute low or null synaptic activity on NMDA receptors and its implications for synaptic plasticity. Periods of no stimulation or low-frequency stimulation increased NMDAR transmission. Changes became stable after periods of 20 min of low or no stimulation. These changes in transmission have a postsynaptic origin and are explained by incorporation of GluN2B-containing receptors to synapses. Importantly, periods of low or no stimulation facilitate long-term potentiation induction. Moreover, recovery after a weak preconditioning stimulus that normally blocks subsequent potentiation is facilitated by a nonstimulation period. Thus synaptic activity dynamically regulates the level of NMDAR transmission adapting constantly the threshold for plasticity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980539"}
{"pmid": "20980541", "title": "Reorganization of finger coordination patterns during adaptation to rotation and scaling of a newly learned sensorimotor transformation.", "content": "Reorganization of finger coordination patterns during adaptation to rotation and scaling of a newly learned sensorimotor transformation. We examined how people organize redundant kinematic control variables (finger joint configurations) while learning to make goal-directed movements of a virtual object (a cursor) within a low-dimensional task space (a computer screen). Subjects participated in three experiments performed on separate days. Learning progressed rapidly on day 1, resulting in reduced target capture error and increased cursor trajectory linearity. On days 2 and 3, one group of subjects adapted to a rotation of the nominal map, imposed either stepwise or randomly over trials. Another group experienced a scaling distortion. We report two findings. First, adaptation rates and memory-dependent motor command updating depended on distortion type. Stepwise application and removal of the rotation induced a marked increase in finger motion variability but scaling did not, suggesting that the rotation initiated a more exhaustive search through the space of viable finger motions to resolve the target capture task than did scaling. Indeed, subjects formed new coordination patterns in compensating the rotation but relied on patterns established during baseline practice to compensate the scaling. These findings support the idea that the brain compensates direction and extent errors separately and in computationally distinct ways, but are inconsistent with the idea that once a task is learned, command updating is limited to those degrees of freedom contributing to performance (thereby minimizing energetic or similar costs of control). Second, we report that subjects who learned a scaling while moving to just one target generalized more narrowly across directions than those who learned a rotation. This contrasts with results from whole-arm reaching studies, where a learned scaling generalizes more broadly across direction than rotation. Based on inverse- and forward-dynamics analyses of reaching with the arm, we propose the difference in results derives from extensive exposure in reaching with familiar arm dynamics versus the novelty of the manual task.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980541"}
{"pmid": "20980543", "title": "An increase in persistent sodium current contributes to intrinsic neuronal bursting after status epilepticus.", "content": "An increase in persistent sodium current contributes to intrinsic neuronal bursting after status epilepticus. Brain damage causes multiple changes in synaptic function and intrinsic properties of surviving neurons, leading to the development of chronic epilepsy. In the widely used pilocarpine-status epilepticus (SE) rat model of temporal lobe epilepsy (TLE), a major alteration is the marked increase in the fraction of intrinsically bursting CA1 pyramidal cells. Here we have differentiated between two types of bursting phenotypes: 1) bursting in response to threshold-straddling excitatory current pulses (low-threshold bursting) and 2) bursting only in response to suprathreshold stimuli (high-threshold bursting). Low-threshold bursting prevailed in 46.5% of SE-experienced neurons sampled 1-4 wk after pilocarpine-SE, but was rarely seen in control neurons (1.9%). As previously shown, it appeared to be driven predominantly by a T-type Ca(2+) current (I(CaT)) in the apical dendrites. After blocking low-threshold bursting with Ni(2+), the same neurons still manifested a high-threshold bursting phenotype. Another 40.1% of SE-experienced neurons displayed only a high-threshold bursting phenotype and the remaining 13.4% of these neurons were nonbursters. Altogether, high-threshold bursting prevailed in 86.6% of SE-experienced neurons, but only in 33.0% of control neurons. Several lines of evidence indicated that high-threshold bursting is driven by persistent Na(+) current (I(NaP)) at or near the soma. Congruently, I(NaP) was 1.5-fold larger in SE-experienced versus control neurons. We conclude that an increase in I(NaP), conjointly with an increase in I(CaT), strongly contributes to the predominance of bursting phenotypes in CA1 pyramidal cells early after pilocarpine-SE and thus likely plays a role in the development of a chronic epileptic condition in this TLE model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980543"}
{"pmid": "20980544", "title": "The pedunculopontine tegmental nucleus: a second cholinergic source for frequency-specific auditory plasticity.", "content": "The pedunculopontine tegmental nucleus: a second cholinergic source for frequency-specific auditory plasticity. Cholinergic modulation is essential for many brain functions and is an indispensable component of the prevalent models attempting to understand the neural mechanism responsible for learning-induced auditory plasticity. Unlike the cholinergic basal forebrain, the cholinergic pedunculopontine tegmental nucleus (PPTg) has received little attention. This study was designed to confirm whether the PPTg enables frequency-specific plasticity in the ventral division of the medial geniculate body of the thalamus (MGBv). Using the mouse model, we paired electrical stimulation of the PPTg with tone stimulation to help define the role of the PPTg. The receptive fields of MGBv neurons were examined before and after the paired stimulation; they were quantified in this study by best frequency (BF), response threshold, dynamic range, and spike number. We found that the electrical stimulation of the PPTg together with a tone presentation shifted the BFs of MGBv neurons upward when the frequency of the paired tone was higher than that of the control BF. Similarly, the BFs shifted downward when the frequency of the paired tone was lower than that of the control BF. The BFs of MGBv neurons, however, remained unchanged when the frequency of the paired tone was the same as that of the control BF. There was a linear relationship between the BF shift of MGBv neurons and the difference between the frequency of the paired tone and the control BF of MGBv neurons. Highly frequency specific changes were also observed in the response threshold, dynamic range, and spike number. This frequency-specific plasticity was largely eliminated by the microinjection of the muscarinic receptor antagonist atropine into the MGBv before the paired stimulation. Our findings suggest that the PPTg, like the cholinergic basal forebrain, is an important cholinergic source that enables frequency-specific plasticity in the central auditory system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980544"}
{"pmid": "20980545", "title": "Area MSTd neurons encode visual stimuli in eye coordinates during fixation and pursuit.", "content": "Area MSTd neurons encode visual stimuli in eye coordinates during fixation and pursuit. Visual signals generated by self-motion are initially represented in retinal coordinates in the early parts of the visual system. Because this information can be used by an observer to navigate through the environment, it must be transformed into body or world coordinates at later stations of the visual-motor pathway. Neurons in the dorsal aspect of the medial superior temporal area (MSTd) are tuned to the focus of expansion (FOE) of the visual image. We performed experiments to determine whether focus tuning curves in area MSTd are represented in eye coordinates or in screen coordinates (which could be head, body, or world-centered in the head-fixed paradigm used). Because MSTd neurons adjust their FOE tuning curves during pursuit eye movements to compensate for changes in pursuit and translation speed that distort the visual image, the coordinate frame was determined while the eyes were stationary (fixed gaze or simulated pursuit conditions) and while the eyes were moving (real pursuit condition). We recorded extracellular responses from 80 MSTd neurons in two rhesus monkeys (Macaca mulatta). We found that the FOE tuning curves of the overwhelming majority of neurons were aligned in an eye-centered coordinate frame in each of the experimental conditions [fixed gaze: 77/80 (96%); real pursuit: 77/80 (96%); simulated pursuit 74/80 (93%); t-test, P < 0.05]. These results indicate that MSTd neurons represent heading in an eye-centered coordinate frame both when the eyes are stationary and when they are moving. We also found that area MSTd demonstrates significant eye position gain modulation of response fields much like its posterior parietal neighbors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980545"}
{"pmid": "20980546", "title": "Potentiation of synaptic AMPA receptors induced by the deletion of NMDA receptors requires the GluA2 subunit.", "content": "Potentiation of synaptic AMPA receptors induced by the deletion of NMDA receptors requires the GluA2 subunit. Deletion of N-methyl-D-aspartate receptors (NMDARs) early in development results in an increase in the number of synaptic AMPA receptors (AMPARs), suggesting a role for NMDARs in negatively regulating AMPAR trafficking at developing synapses. Substantial evidence has shown that AMPAR subunits function differentially in AMPAR trafficking. However, the role of AMPAR subunits in the enhancement of AMPARs following NMDAR ablation remains unknown. We have now performed single-cell genetic deletions in double-floxed mice in which the deletion of GluN1 is combined with the deletion of GluA1 or GluA2. We find that the AMPAR enhancement following NMDAR deletion requires the GluA2 subunit, but not the GluA1 subunit, indicating a key role for GluA2 in the regulation of AMPAR trafficking in developing synapses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980546"}
{"pmid": "20980542", "title": "Phasic and tonic patterns of locus coeruleus output differentially modulate sensory network function in the awake rat.", "content": "Phasic and tonic patterns of locus coeruleus output differentially modulate sensory network function in the awake rat. Neurons of the nucleus locus coeruleus (LC) discharge with phasic bursts of activity superimposed on highly regular tonic discharge rates. Phasic bursts are elicited by bottom-up input mechanisms involving novel/salient sensory stimuli and top-down decision making processes; whereas tonic rates largely fluctuate according to arousal levels and behavioral states. Although it is generally believed that these two modes of activity differentially modulate information processing in LC targets, the unique role of phasic versus tonic LC output on signal processing in cells, circuits, and neural networks of waking animals is not well understood. In the current study, simultaneous recordings of individual neurons within ventral posterior medial thalamus and barrel field cortex of conscious rats provided evidence that each mode of LC output produces a unique modulatory impact on single neuron responsiveness to sensory-driven synaptic input and representations of sensory information across ensembles of simultaneously recorded cells. Each mode of LC activation specifically modulated the relationship between sensory-stimulus intensity and the subsequent responses of individual neurons and neural ensembles. Overall these results indicate that phasic versus tonic modes of LC discharge exert fundamentally different modulatory effects on target neuronal circuits within the rodent trigeminal somatosensory system. As such, each mode of LC output may differentially influence signal processing as a means of optimizing behaviorally relevant neural computations within this sensory network. Likely the ability of the LC system to differentially regulate neural responses and local circuit operations according to behavioral demands extends to other brain regions including those involved in higher cognitive functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980542"}
{"pmid": "20980548", "title": "Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.", "content": "Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2. The human Na(+)/D-glucose cotransporter 2 (hSGLT2) is believed to be responsible for the bulk of glucose reabsorption in the kidney proximal convoluted tubule. Since blocking reabsorption increases urinary glucose excretion, hSGLT2 has become a novel drug target for Type 2 diabetes treatment. Glucose transport by hSGLT2 was studied at 37°C in human embryonic kidney 293T cells using whole cell patch-clamp electrophysiology. We compared hSGLT2 with hSGLT1, the transporter in the straight proximal tubule (S3 segment). hSGLT2 transports with surprisingly similar glucose affinity and lower concentrative power than hSGLT1: Na(+)/D-glucose cotransport by hSGLT2 was electrogenic with apparent glucose and Na(+) affinities of 5 and 25 mM, and a Na(+):glucose coupling ratio of 1; hSGLT1 affinities were 2 and 70 mM and coupling ratio of 2. Both proteins showed voltage-dependent steady-state transport; however, unlike hSGLT1, hSGLT2 did not exhibit detectable pre-steady-state currents in response to rapid jumps in membrane voltage. D-Galactose was transported by both proteins, but with very low affinity by hSGLT2 (≥100 vs. 6 mM). β-D-Glucopyranosides were either substrates or blockers. Phlorizin exhibited higher affinity with hSGLT2 (K(i) 11 vs. 140 nM) and a lower Off-rate (0.03 vs. 0.2 s⁻¹) compared with hSGLT1. These studies indicate that, in the early proximal tubule, hSGLT2 works at 50% capacity and becomes saturated only when glucose is ≥35 mM. Furthermore, results on hSGLT1 suggest it may play a significant role in the reabsorption of filtered glucose in the late proximal tubule. Our electrophysiological study provides groundwork for a molecular understanding of how hSGLT inhibitors affect renal glucose reabsorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980548"}
{"pmid": "20980549", "title": "Posttranscriptional mechanisms involving microRNA-27a and b contribute to fast-specific and glucocorticoid-mediated myostatin expression in skeletal muscle.", "content": "Posttranscriptional mechanisms involving microRNA-27a and b contribute to fast-specific and glucocorticoid-mediated myostatin expression in skeletal muscle. Expression of the antigrowth factor myostatin (MSTN) differs between fast and slow skeletal muscles and is increased in nearly every form of muscle atrophy, but the contribution of transcriptional vs. posttranscriptional mechanisms to its differing expression in these states has not been defined. We show here that levels of mature MSTN mRNA were sixfold greater in fast vs. slow muscle and were increased twofold in fast muscle in response to dexamethasone (Dex) injection in vivo and in C₂C₁₂ myotubes following Dex treatment in vitro, but that levels of MSTN pre-mRNA, a readout of transcription, only minimally and nonsignificantly differed in these states. Moreover, Dex treatment with or without cotransfection with a glucocorticoid receptor expression construct had only modest effects on mouse MSTN promoter activity in C₂C₁₂ myotubes. We therefore explored the potential contribution of posttranscriptional mechanisms, and the role of the microRNAs miR-27a and b in particular, on MSTN expression. The MSTN 3'-untranslated region (UTR) contains a putative recognition sequence for miR-27a and b that is conserved across a wide range of vertebrate species. Cotransfection of a MSTN 3'-UTR-luciferase construct with a miR-27b expression construct significantly attenuated by approximately half while mutation of the miR-27 recognition sequence significantly increased by approximately twofold the activity of a MSTN 3'-UTR construct and decreased mRNA degradation of a luciferase reporter construct in C₂C₁₂ myotubes. Expression of miR-27a and b was almost sixfold greater in slow-twitch than in fast-twitch muscle in vivo, and miR-27a expression was significantly decreased by nearly half by glucocorticoid treatment in vitro. Finally, the miR-27a and b promoters were activated by cotransfection with the slow-specific signaling molecules calcineurin and peroxisome proliferator-activated receptor-γ coactivator-1α. The present data represent the first demonstration that posttranscriptional mechanisms involving miR-27a and b may contribute to fast-specific and glucocorticoid-dependent myostatin expression in muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980549"}
{"pmid": "20980550", "title": "Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism.", "content": "Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism. Actions of angiotensin-(1-7) [Ang-(1-7)], a heptapeptide of the renin-angiotensin system, in the periphery are mediated, at least in part, by activation of nitric oxide (NO) synthase (NOS) and generation NO(·). Studies of the central nervous system have shown that NO(·) acts as a sympathoinhibitory molecule and thus may play a protective role in neurocardiovascular diseases associated with sympathoexcitation, such as hypertension and heart failure. However, the contribution of NO in the intraneuronal signaling pathway of Ang-(1-7) and the subsequent modulation of neuronal activity remains unclear. Here, we tested the hypothesis that neuronal NOS (nNOS)-derived NO(·) mediates changes in neuronal activity following Ang-(1-7) stimulation. For these studies, we used differentiated catecholaminergic (CATH.a) neurons, which we show express the Ang-(1-7) receptor (Mas R) and nNOS. Stimulation of CATH.a neurons with Ang-(1-7) (100 nM) increased intracellular NO levels, as measured by 4-amino-5-methylamino-2',7'-difluorofluorescein diacetate (DAF-FM) fluorescence and confocal microscopy. This response was significantly attenuated in neurons pretreated with the Mas R antagonist (A-779), a nonspecific NOS inhibitor (nitro-L-arginine methyl ester), or an nNOS inhibitor (S-methyl-L-thiocitrulline, SMTC), but not by endothelial NOS (eNOS) or inhibitory NOS (iNOS) inhibition {L-N-5-(1-iminoethyl)ornithine (L-NIO) and 1400W, respectively}. To examine the effect of Ang-(1-7)-NO(·) signaling on neuronal activity, we recorded voltage-gated outward K(+) current (I(Kv)) in CATH.a neurons using the whole cell configuration of the patch-clamp technique. Ang-(1-7) significantly increased I(Kv), and this response was inhibited by A-779 or S-methyl-L-thiocitrulline, but not L-NIO or 1400W. These findings indicate that Ang-(1-7) is capable of increasing nNOS-derived NO(·) levels, which in turn, activates hyperpolarizing I(Kv) in catecholaminergic neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980550"}
{"pmid": "20980551", "title": "Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets.", "content": "Hypoxia. 1. Intracellular sensors for oxygen and oxidative stress: novel therapeutic targets. A variety of human disorders, e.g., ischemic heart disease, stroke, kidney disease, eventually share the deleterious consequences of a common, hypoxic and oxidative stress pathway. In this review, we utilize recent information on the cellular defense mechanisms against hypoxia and oxidative stress with the hope to propose new therapeutic tools. The hypoxia-inducible factor (HIF) is a key player as it activates a broad range of genes protecting cells against hypoxia. Its level is determined by its degradation rate by intracellular oxygen sensors prolyl hydroxylases (PHDs). There are three different PHD isoforms (PHD1-3). Small molecule PHD inhibitors improve hypoxic injury in experimental animals but, unfortunately, may induce adverse effects associated with PHD2 inhibition, e.g., angiogenesis. As yet, no inhibitor specific for a distinct PHD isoform is currently available. Still, the specific disruption of the PHD1 gene is known to induce hypoxic tolerance, without angiogenesis and erythrocytosis, by reprogramming basal oxygen metabolism with an attendant decreased oxidative stress in hypoxic mitochondria. A specific PHD1 inhibitor might therefore offer a novel therapy against hypoxia. The nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) regulates the basal and inducible expression of numerous antioxidant stress genes. Disruption of its gene exacerbates oxidative tissue injury. Nrf2 activity is modulated by Kelch-like ECH-associated protein 1 (Keap1), an intracellular sensor for oxidative stress. Inhibitors of Keap 1 may prove therapeutic against oxidative tissue injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980551"}
{"pmid": "20980552", "title": "Contribution of K(ir)2 potassium channels to ATP-induced cell death in brain capillary endothelial cells and reconstructed HEK293 cell model.", "content": "Contribution of K(ir)2 potassium channels to ATP-induced cell death in brain capillary endothelial cells and reconstructed HEK293 cell model. Cellular turnover of brain capillary endothelial cells (BCECs) by the balance of cell proliferation and death is essential for maintaining the homeostasis of the blood-brain barrier. Stimulation of metabotropic ATP receptors (P2Y) transiently increased intracellular Ca²(+) concentration ([Ca²(+)](i)) in t-BBEC 117, a cell line derived from bovine BCECs. The [Ca²(+)](i) rise induced membrane hyperpolarization via the activation of apamin-sensitive small-conductance Ca²(+)-activated K(+) channels (SK2) and enhanced cell proliferation in t-BBEC 117. Here, we found anomalous membrane hyperpolarization lasting for over 10 min in response to ATP in ∼15% of t-BBEC 117, in which inward rectifier K(+) channel (K(ir)2.1) was extensively expressed. Once anomalous hyperpolarization was triggered by ATP, it was removed by Ba²(+) but not by apamin. Prolonged exposure to ATPγS increased the relative population of t-BBEC 117, in which the expression of K(ir)2.1 mRNAs was significantly higher and Ba²(+)-sensitive anomalous hyperpolarization was observed. The cultivation of t-BBEC 117 in serum-free medium also increased this population and reduced the cell number. The reduction of cell number was enhanced by the addition of ATPγS and the enhancement was antagonized by Ba²(+). In the human embryonic kidney 293 cell model, where SK2 and K(ir)2.1 were heterologously coexpressed, [Ca²(+)](i) rise by P2Y stimulation triggered anomalous hyperpolarization and cell death. In conclusion, P2Y stimulation in BCECs enhances cell proliferation by SK2 activation in the majority of cells but also triggers cell death in a certain population showing a substantial expression of K(ir)2.1. This dual action of P2Y stimulation may effectively facilitate BCEC turnover.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980552"}
{"pmid": "20980547", "title": "Brain tumor imaging: posttherapy.", "content": "Brain tumor imaging: posttherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980547"}
{"pmid": "20980553", "title": "Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans.", "content": "Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans. High-throughput sequencing has recently begun to revolutionize the study of structural variants in the genomes of humans and other species. More recently, this technology and others have been applied to the study of human retrotransposon insertion polymorphisms (RIPs), yielding an unprecedented catalog of common and rare variants due to insertional mutagenesis. At the same time, the 1000 Genomes Project has released an enormous amount of whole-genome sequence data. In this article, we present evidence for 1016 L1 insertions across all studies to date that are not represented in the reference human genome assembly, many of which appear to be specific to populations or groups of populations, particularly Africans. Additionally, a cross-comparison of several studies shows that, on average, 27% of surveyed nonreference insertions is present in only one study, indicating the low frequency of many RIPs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980553"}
{"pmid": "20980554", "title": "Scaffolding a Caenorhabditis nematode genome with RNA-seq.", "content": "Scaffolding a Caenorhabditis nematode genome with RNA-seq. Efficient sequencing of animal and plant genomes by next-generation technology should allow many neglected organisms of biological and medical importance to be better understood. As a test case, we have assembled a draft genome of Caenorhabditis sp. 3 PS1010 through a combination of direct sequencing and scaffolding with RNA-seq. We first sequenced genomic DNA and mixed-stage cDNA using paired 75-nt reads from an Illumina GAII. A set of 230 million genomic reads yielded an 80-Mb assembly, with a supercontig N50 of 5.0 kb, covering 90% of 429 kb from previously published genomic contigs. Mixed-stage poly(A)(+) cDNA gave 47.3 million mappable 75-mers (including 5.1 million spliced reads), which separately assembled into 17.8 Mb of cDNA, with an N50 of 1.06 kb. By further scaffolding our genomic supercontigs with cDNA, we increased their N50 to 9.4 kb, nearly double the average gene size in C. elegans. We predicted 22,851 protein-coding genes, and detected expression in 78% of them. Multigenome alignment and data filtering identified 2672 DNA elements conserved between PS1010 and C. elegans that are likely to encode regulatory sequences or previously unknown ncRNAs. Genomic and cDNA sequencing followed by joint assembly is a rapid and useful strategy for biological analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980554"}
{"pmid": "20980556", "title": "Stampy: a statistical algorithm for sensitive and fast mapping of Illumina sequence reads.", "content": "Stampy: a statistical algorithm for sensitive and fast mapping of Illumina sequence reads. High-volume sequencing of DNA and RNA is now within reach of any research laboratory and is quickly becoming established as a key research tool. In many workflows, each of the short sequences (\"reads\") resulting from a sequencing run are first \"mapped\" (aligned) to a reference sequence to infer the read from which the genomic location derived, a challenging task because of the high data volumes and often large genomes. Existing read mapping software excel in either speed (e.g., BWA, Bowtie, ELAND) or sensitivity (e.g., Novoalign), but not in both. In addition, performance often deteriorates in the presence of sequence variation, particularly so for short insertions and deletions (indels). Here, we present a read mapper, Stampy, which uses a hybrid mapping algorithm and a detailed statistical model to achieve both speed and sensitivity, particularly when reads include sequence variation. This results in a higher useable sequence yield and improved accuracy compared to that of existing software.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980556"}
{"pmid": "20980555", "title": "Dindel: accurate indel calls from short-read data.", "content": "Dindel: accurate indel calls from short-read data. Small insertions and deletions (indels) are a common and functionally important type of sequence polymorphism. Most of the focus of studies of sequence variation is on single nucleotide variants (SNVs) and large structural variants. In principle, high-throughput sequencing studies should allow identification of indels just as SNVs. However, inference of indels from next-generation sequence data is challenging, and so far methods for identifying indels lag behind methods for calling SNVs in terms of sensitivity and specificity. We propose a Bayesian method to call indels from short-read sequence data in individuals and populations by realigning reads to candidate haplotypes that represent alternative sequence to the reference. The candidate haplotypes are formed by combining candidate indels and SNVs identified by the read mapper, while allowing for known sequence variants or candidates from other methods to be included. In our probabilistic realignment model we account for base-calling errors, mapping errors, and also, importantly, for increased sequencing error indel rates in long homopolymer runs. We show that our method is sensitive and achieves low false discovery rates on simulated and real data sets, although challenges remain. The algorithm is implemented in the program Dindel, which has been used in the 1000 Genomes Project call sets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980555"}
{"pmid": "20980558", "title": "Are nasal carriers of Staphylococcus aureus more likely to become colonized or infected with methicillin-resistant Staphylococcus aureus on admission to a hospital?", "content": "Are nasal carriers of Staphylococcus aureus more likely to become colonized or infected with methicillin-resistant Staphylococcus aureus on admission to a hospital? Of 840 patients at hospital admission, 2.7% were positive for methicillin-resistant Staphylococcus aureus (MRSA) and 22.3% were positive for methicillin-susceptible S. aureus (MSSA). During the next 8 months, 4.8% of the MSSA-positive patients acquired MRSA with no lineage association. A total of 5.2% of noncarriers acquired MRSA. We find no evidence that colonized hosts are more susceptible to acquiring MRSA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980558"}
{"pmid": "20980557", "title": "SNP detection and genotyping from low-coverage sequencing data on multiple diploid samples.", "content": "SNP detection and genotyping from low-coverage sequencing data on multiple diploid samples. Reductions in the cost of sequencing have enabled whole-genome sequencing to identify sequence variants segregating in a population. An efficient approach is to sequence many samples at low coverage, then to combine data across samples to detect shared variants. Here, we present methods to discover and genotype single-nucleotide polymorphism (SNP) sites from low-coverage sequencing data, making use of shared haplotype (linkage disequilibrium) information. For each population, we first collect SNP candidates based on independent sequence calls per site. We then use MARGARITA with genotype or phased haplotype data from the same samples to collect 20 ancestral recombination graphs (ARGs). We refine the posterior probability of SNP candidates by considering possible mutations at internal branches of the 40 marginal ancestral trees inferred from the 20 ARGs at the left and right flanking genotype sites. Using a population genetic prior distribution on tree-branch length and Bayesian inference, we determine a posterior probability of the SNP being real and also the most probable phased genotype call for each individual. We present experiments on both simulation data and real data from the 1000 Genomes Project to prove the applicability of the methods. We also explore the relative tradeoff between sequencing depth and the number of sequenced samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980557"}
{"pmid": "20980559", "title": "Screening for Acinetobacter baumannii colonization by use of sponges.", "content": "Screening for Acinetobacter baumannii colonization by use of sponges. There is currently no consensus method for the active screening of Acinetobacter baumannii. The use of swabs to culture nostrils, pharynx, and skin surface of various anatomical sites is known to yield less-than-optimal sensitivity. In the present study, we sought to determine whether the use of sterile sponges to sample large areas of the skin would improve the sensitivity of the detection of A. baumannii colonization. Forty-six patients known to be colonized with A. baumannii, defined by a positive clinical culture for this organism as defined by resistance to more than two classes of antimicrobials, participated in the study. The screening sites included the forehead, nostrils, buccal mucosa, axilla, antecubital fossa, groin, and toe webs with separate rayon swabs and the forehead, upper arm, and thigh with separate sponges. Modified Leeds Acinetobacter medium (mLAM) agar plates that contained vancomycin and either aztreonam or ceftazidime were used as the selective medium. An enrichment culture grown overnight substantially increased the sensitivity for most sites. The sensitivity ranged between 69.6 and 82.6% for individual sponge sites and 21.7 to 52.2% for individual swab sites when mLAM plates with ceftazidime were inoculated after a 24-h enrichment period. The sponge and swab sites with the best sensitivity were the leg and the buccal mucosa, respectively (82.6% and 52.2%; P = 0.003). The combined sensitivity for the upper arm and leg with a sponge was 89.1%. The novel screening method using sterile sponges was easy to perform and achieved excellent sensitivity for the detection of A. baumannii colonization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980559"}
{"pmid": "20980560", "title": "Toward molecular parasitologic diagnosis: enhanced diagnostic sensitivity for filarial infections in mobile populations.", "content": "Toward molecular parasitologic diagnosis: enhanced diagnostic sensitivity for filarial infections in mobile populations. The diagnosis of filarial infections among individuals residing in areas where the disease is not endemic requires both strong clinical suspicion and expert training in infrequently practiced parasitological methods. Recently developed filarial molecular diagnostic assays are highly sensitive and specific but have limited availability and have not been closely evaluated for clinical use outside populations residing in areas of endemicity. In this study, we assessed the performance of a panel of real-time PCR assays for the four most common human filarial pathogens among blood and tissue samples collected from a cohort of patients undergoing evaluation for suspected filarial infections. Compared to blood filtration, real-time PCR was equally sensitive for the detection of microfilaremia due to Wuchereria bancrofti (2 of 46 samples positive by both blood filtration and PCR with no discordant results) and Loa loa (24 of 208 samples positive by both blood filtration and PCR, 4 samples positive by PCR only, and 3 samples positive by blood filtration only). Real-time PCR of skin snip samples was significantly more sensitive than microscopic examination for the detection of Onchocerca volvulus microfiladermia (2 of 218 samples positive by both microscopy and PCR and 12 samples positive by PCR only). The molecular assays required smaller amounts of blood and tissue than conventional methods and could be performed by laboratory personnel without specialized parasitology training. Taken together, these data demonstrate the utility of the molecular diagnosis of filarial infections in mobile populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980560"}
{"pmid": "20980562", "title": "Comparison of real-time PCR techniques to cytotoxigenic culture methods for diagnosing Clostridium difficile infection.", "content": "Comparison of real-time PCR techniques to cytotoxigenic culture methods for diagnosing Clostridium difficile infection. In the past decade, the incidence of Clostridium difficile infections (CDI) with a more severe course has increased in Europe and North America. Assays that are capable of rapidly diagnosing CDI are essential. Two real-time PCRs (LUMC and LvI) targeting C. difficile toxin genes (tcdB, and tcdA and tcdB, respectively) were compared with the BD GeneOhm PCR (targeting the tcdB gene), using cytotoxigenic culture as a gold standard. In addition, a real-time PCR targeting the tcdC frameshift mutation at position 117 (Δ117 PCR) was evaluated for detecting toxigenic C. difficile and the presence of PCR ribotype 027 in stool samples. In total, 526 diarrheal samples were prospectively collected and included in the study. Compared with those for cytotoxigenic culture, sensitivity, specificity, positive predicted value (PPV), and negative predicted value (NPV) were for PCR LUMC 96.0%, 88.0%, 66.0%, and 98.9%, for PCR LvI 100.0%, 89.4%, 69.7%, and 100.0%, for PCR Δ117 98.0%, 90.7%, 71.9%, and 99.5%, and for PCR BD GeneOhm 88.3%, 96.9%, 86.5%, and 97.4%. Compared to those with feces samples cultured positive for C. difficile type 027, the sensitivity, specificity, PPV, and NPV of the Δ117 PCR were 95.2%, 96.2%, 87.0%, and 98.7%. We conclude that all real-time PCRs can be applied as a first screening test in an algorithm for diagnosing CDI. However, the low PPVs hinder the use of the assays as stand-alone tests. Furthermore, the Δ117 PCR may provide valuable information for minimizing the spread of the epidemic C. difficile PCR ribotype 027.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980562"}
{"pmid": "20980561", "title": "Insertion sequences as highly resolutive genomic markers for sequence type 1 Legionella pneumophila Paris.", "content": "Insertion sequences as highly resolutive genomic markers for sequence type 1 Legionella pneumophila Paris. The causative agent of legionellosis, Legionella pneumophila, colonizes all natural and human-made water networks, thus constituting the source of contaminated aerosols responsible for airborne human infections. Efficient control of infections, especially during epidemics, necessitates the fastest and most resolutive identification possible of the bacterial source for subsequent disinfection of reservoirs. We thus compared recognized typing approaches for Legionella with a method based on characterization of insertion sequence (IS) content. A total of 86 clinical or environmental isolates of L. pneumophila, including 84 Paris isolates, sampled from 25 clinical investigations in France between 2001 and 2007, were obtained from the Legionella National Reference Center. All strains were typed by monoclonal antibody subgrouping, sequence-based typing, pulsed-field gel electrophoresis, and restriction fragment length polymorphism based on the presence or absence of IS elements. We identified six different types of IS elements in L. pneumophila Paris and used them as genomic markers in hybridization experiments. One IS type, ISLpn11, revealed a high discriminatory power. Simpson's index of discrimination, calculated from the distribution of IS elements, was higher than that obtained with the other typing methods used for L. pneumophila Paris. Moreover, specific ISLpn11 copies were found only in strains isolated from particular cities. In more than half of the cases, each clinical isolate had an ISLpn11 profile that was recovered in at least one environmental isolate from the same geographical location, suggesting that our method could identify the infection source. Phylogenetic analysis suggests a clonal expansion for the L. pneumophila Paris strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980561"}
{"pmid": "20980563", "title": "Enteric fever in a 6-year-old traveler caused by Salmonella enterica serotypes Typhi and Paratyphi A: laboratory detection strategies and treatment options.", "content": "Enteric fever in a 6-year-old traveler caused by Salmonella enterica serotypes Typhi and Paratyphi A: laboratory detection strategies and treatment options. We report the first pediatric case of enteric fever caused by Salmonella enterica serotypes Typhi and Paratyphi A. Mixed infections are infrequently reported, potentially because detection of two different Salmonella serotypes in blood cultures is technically challenging. We suggest laboratory strategies to aid in the recognition of mixed infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980563"}
{"pmid": "20980564", "title": "Comparative evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 version 2 test using the TaqMan 48 analyzer and the Abbott RealTime HIV-1 assay.", "content": "Comparative evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 version 2 test using the TaqMan 48 analyzer and the Abbott RealTime HIV-1 assay. Acceptable precision was achieved in a comparison study of the Abbott RealTime (RT) and Roche CAP/CTM-48 V2 HIV-1 assays, but viral load quantification was under- and overestimated, respectively, compared to the 2nd HIV-1 WHO International Standard. The same quantification patterns were observed for patient cohorts from Africa and the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980564"}
{"pmid": "20980565", "title": "Identification by genotyping of a commercial antigen preparation as the source of a laboratory contamination with Coxiella burnetii and as an unexpected rich source of control DNA.", "content": "Identification by genotyping of a commercial antigen preparation as the source of a laboratory contamination with Coxiella burnetii and as an unexpected rich source of control DNA. By performing genotyping, a laboratory contamination involving Q fever was traced back to the antigen preparation used in a commercially available complement fixation test. It was established that such antigen preparations contain relatively high loads of DNA/RNA, making them potential sources of contamination but also convenient preparations for control material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980565"}
{"pmid": "20980566", "title": "Genotyping of Enterococcus faecalis and Enterococcus faecium isolates by use of a set of eight single nucleotide polymorphisms.", "content": "Genotyping of Enterococcus faecalis and Enterococcus faecium isolates by use of a set of eight single nucleotide polymorphisms. A single nucleotide polymorphism (SNP) genotyping method for Enterococcus faecalis and Enterococcus faecium was developed using the \"Minimum SNPs\" program. SNP sets were interrogated using allele-specific real-time PCR. SNP typing subdivided clonal complexes 2 and 9 of E. faecalis and 17 of E. faecium, members of which cause the majority of nosocomial infections globally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980566"}
{"pmid": "20980567", "title": "Emergence of a unique penicillin-resistant Streptococcus pneumoniae serogroup 35 strain.", "content": "Emergence of a unique penicillin-resistant Streptococcus pneumoniae serogroup 35 strain. We analyzed seven Streptococcus pneumoniae serogroup 35 isolates by pulsed-field gel electrophoresis of the genome and pbp2b gene nucleotide sequences. Three penicillin-susceptible strains and one penicillin-intermediate-resistant strain exhibited 100% identity to prototype R6. Two resistant strains and one other intermediate strain differed from them and contained a unique sequence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980567"}
{"pmid": "20980568", "title": "What is the current role of algorithmic approaches for diagnosis of Clostridium difficile infection?", "content": "What is the current role of algorithmic approaches for diagnosis of Clostridium difficile infection? With the recognition of several serious outbreaks of Clostridium difficile infection in the industrialized world coupled with the development of new testing technologies for detection of this organism, there has been renewed interest in the laboratory diagnosis of C. difficile infection. Two factors seem to have driven much of this interest. First, the recognition that immunoassays for detection of C. difficile toxins A and B, for many years the most widely used tests for C. difficile infection diagnosis, were perhaps not as sensitive as previously believed at a time when attributed deaths to C. difficile infections were showing a remarkable rise. Second, the availability of FDA-approved commercial and laboratory-developed PCR assays which could detect toxigenic strains of C. difficile provided a novel and promising testing approach for diagnosing this infection. In this point-counterpoint on the laboratory diagnosis of C. difficile infection, we have asked two experts in C. difficile infection diagnosis, Ferric Fang, who has recently published two articles in the Journal of Clinical Microbiology advocating the use of PCR as a standalone test (see this author's references 12 and 28), and Mark Wilcox, who played a key role in developing the IDSA/SHEA guidelines on Clostridium difficile infection (see Wilcox and Planche's reference 1), along with his colleague, Tim Planche, to address the following question: what is the current role of algorithmic approaches to the diagnosis of C. difficile infection?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980568"}
{"pmid": "20980569", "title": "National surveillance of fungemia in Denmark (2004 to 2009).", "content": "National surveillance of fungemia in Denmark (2004 to 2009). A 6-year nationwide study of fungemia in Denmark was performed using data from an active fungemia surveillance program and from laboratory information systems in nonparticipating regions. A total of 2,820 episodes of fungemia were recorded. The incidence increased from 2004 to 2007 (7.7 to 9.6/100,000) and decreased slightly from 2008 to 2009 (8.7 to 8.6/100,000). The highest incidences were seen at the extremes of age (i.e., 11.3 and 37.1/100,000 for those <1 and 70 to 79 years old, respectively). The rate was higher for males than for females (10.1 versus 7.6/100,000, P = 0.003), with the largest difference observed for patients >50 years of age. The species distribution varied significantly by both age and gender. Candida species accounted for 98% of the pathogens, and C. albicans was predominant, although the proportion decreased (64.4% to 53.2%, P < 0.0001). C. glabrata ranked second, and the proportion increased (16.5% to 25.9%, P = 0.003). C. glabrata was more common in adults and females than in children and males, whereas C. tropicalis was more common in males (P = 0.020). C. krusei was a rare isolate (4.1%) except at one university hospital. Acquired resistance to amphotericin and echinocandins was rare. However, resistance to fluconazole (MIC of >4 μg/ml) occurred in C. albicans (7/1,183 [0.6%]), C. dubliniensis (2/65 [3.1%]), C. parapsilosis (5/83 [6.0%]), and C. tropicalis (7/104 [6.7%]). Overall, 70.8% of fungemia isolates were fully fluconazole susceptible, but the proportion decreased (79.7% to 68.9%, P = 0.02). The study confirmed an incidence rate of fungemia in Denmark three times higher than those in other Nordic countries and identified marked differences related to age and gender. Decreased susceptibility to fluconazole was frequent and increasing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980569"}
{"pmid": "20980571", "title": "Mixed infection with Beijing and non-Beijing strains and drug resistance pattern of Mycobacterium tuberculosis.", "content": "Mixed infection with Beijing and non-Beijing strains and drug resistance pattern of Mycobacterium tuberculosis. Mixed infection with Beijing and non-Beijing strains of Mycobacterium tuberculosis has been reported and has been suggested to mediate elevation of the reinfection rate in regions with a high incidence of tuberculosis (TB). To evaluate the prevalence of infection with both Beijing and non-Beijing strains of M. tuberculosis in eastern Taiwan, the region with the highest TB incidence in Taiwan, 185 active pulmonary TB patients were enrolled at Tzu Chi General Hospital from October 2007 to September 2008. A modified multiplex PCR method was developed to distinguish Beijing and non-Beijing strains directly using the sputum of patients. Of the 185 patients, 46.5% were infected with a Beijing strain, 42.2% were infected with a non-Beijing strain, and 11.3% were infected with both strain types. Notably, mixed infection with both strain types was not associated with TB treatment history or the high-incidence race group, aborigines. In addition, the incidence rate of mixed infection before treatment with anti-TB medication was as high as that in patients with a history of anti-TB treatment. Further analysis of antibiotic susceptibility revealed that Beijing strains alone had the highest multidrug resistance rate (17.5%), mixed infection had the highest rate of resistance to at least one drug (23.8%), and non-Beijing strains had the highest rate of sensitivity to all drugs (79.5%), implying that Beijing strains are predominant in the development of drug resistance in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980571"}
{"pmid": "20980570", "title": "Simultaneous analysis of multiple enzymes increases accuracy of pulsed-field gel electrophoresis in assigning genetic relationships among homogeneous Salmonella strains.", "content": "Simultaneous analysis of multiple enzymes increases accuracy of pulsed-field gel electrophoresis in assigning genetic relationships among homogeneous Salmonella strains. Due to a highly homogeneous genetic composition, the subtyping of Salmonella enterica serovar Enteritidis strains to an epidemiologically relevant level remains intangible for pulsed-field gel electrophoresis (PFGE). We reported previously on a highly discriminatory PFGE-based subtyping scheme for S. enterica serovar Enteritidis that relies on a single combined cluster analysis of multiple restriction enzymes. However, the ability of a subtyping method to correctly infer genetic relatedness among outbreak strains is also essential for effective molecular epidemiological traceback. In this study, genetic and phylogenetic analyses were performed to assess whether concatenated enzyme methods can cluster closely related salmonellae into epidemiologically relevant hierarchies. PFGE profiles were generated by use of six restriction enzymes (XbaI, BlnI, SpeI, SfiI, PacI, and NotI) for 74 strains each of S. enterica serovar Enteritidis and S. enterica serovar Typhimurium. Correlation analysis of Dice similarity coefficients for all pairwise strain comparisons underscored the importance of combining multiple enzymes for the accurate assignment of genetic relatedness among Salmonella strains. The mean correlation increased from 81% and 41% for single-enzyme PFGE up to 99% and 96% for five-enzyme combined PFGE for S. enterica serovar Enteritidis and S. enterica serovar Typhimurium strains, respectively. Data regressions approached 100% correlation among Dice similarities for S. enterica serovar Enteritidis and S. enterica serovar Typhimurium strains when a minimum of six enzymes were concatenated. Phylogenetic congruence measures singled out XbaI, BlnI, SfiI, and PacI as most concordant for S. enterica serovar Enteritidis, while XbaI, BlnI, and SpeI were most concordant among S. enterica serovar Typhimurium strains. Together, these data indicate that PFGE coupled with sufficient enzyme numbers and combinations is capable of discerning accurate genetic relationships among Salmonella serovars comprising highly homogeneous strain complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980570"}
{"pmid": "20980572", "title": "Antimicrobial susceptibility testing and profiling of Nocardia species and other aerobic actinomycetes from South Africa: comparative evaluation of broth microdilution versus the Etest.", "content": "Antimicrobial susceptibility testing and profiling of Nocardia species and other aerobic actinomycetes from South Africa: comparative evaluation of broth microdilution versus the Etest. Nocardiosis is an underrecognized clinical entity in South Africa, for which interspecies epidemiological and clinical differences are poorly understood. The taxonomical state of flux and the lack of a simple antimicrobial susceptibility testing method are partly responsible. Definitive identification is molecularly based, which further complicates the study of this ubiquitous organism, as this methodology is beyond the scope of most routine diagnostic laboratories. The Etest methodology has been proposed as an alternative to the reference broth microdilution method, although there have been a limited number of comparative studies. We profiled 51 clinical isolates of aerobic actinomycetes, including 39 Nocardia species, using sequence-based (16S rRNA) identification. Broth microdilution and Etests were done concurrently on all isolates. The overall level of categorical and essential agreement for broth microdilution and Etest for the Nocardia isolates ranged from 67.5 to 100% and 46.2 to 81.6%, respectively. Very major errors were seen with amikacin, amoxicillin-clavulanate, ciprofloxacin, clarithromycin, and imipenem. For Nocardia species, uniform susceptibility to co-trimoxazole, amikacin, and linezolid was demonstrated, with a 48.8% susceptibility rate to imipenem. Nocardia farcinica (20.5%) and Nocardia cyriacigeorgica (15.4%) were the most commonly identified species among the 82% of isolates identified to species level using 16S rRNA sequences. Furthermore, drug susceptibility patterns demonstrated limited concordance with species identification. Our results suggest that, in a routine diagnostic setting, the Etest is not an acceptable alternative to the reference method of broth microdilution for antimicrobial susceptibility testing. Given the diversity and limited understanding of this group of organisms, further widespread evaluation of clinical isolates, from both clinical and diagnostic perspectives, is warranted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980572"}
{"pmid": "20980573", "title": "Intrafamilial cluster of pulmonary tuberculosis due to Mycobacterium bovis of the African 1 clonal complex.", "content": "Intrafamilial cluster of pulmonary tuberculosis due to Mycobacterium bovis of the African 1 clonal complex. A new clonal complex of Mycobacterium bovis present at high frequency in cattle from west central African countries has been described as the African 1 (Af1) clonal complex. Here, the first intrafamilial cluster of human tuberculosis cases due to M. bovis Af1 clonal complex strains is reported. We discuss hypotheses regarding modes of transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980573"}
{"pmid": "20980575", "title": "Meningitis due to Providencia stuartii.", "content": "Meningitis due to Providencia stuartii. In this report, we present a case of postneurosurgical meningitis due to Providencia stuartii, which was treated successfully with meropenem therapy lasting 21 days.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980575"}
{"pmid": "20980576", "title": "Mixed-strain Mycobacterium tuberculosis infections among patients dying in a hospital in KwaZulu-Natal, South Africa.", "content": "Mixed-strain Mycobacterium tuberculosis infections among patients dying in a hospital in KwaZulu-Natal, South Africa. We performed spoligotyping and 24-locus mycobacterial interspersed repetitive-unit-variable-number tandem-repeat (MIRU-VNTR) typing on M. tuberculosis culture-positive biopsy specimens collected from adults dying in a hospital in KwaZulu-Natal. Of 56 culture-positive samples genotyped, we detected mixed strains in five (9%) and clonal heterogeneity in an additional four (7%).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980576"}
{"pmid": "20980577", "title": "Development of a multilocus sequence tool for typing Cryptosporidium muris and Cryptosporidium andersoni.", "content": "Development of a multilocus sequence tool for typing Cryptosporidium muris and Cryptosporidium andersoni. Although widely used for the characterization of the transmission of intestinal Cryptosporidium spp., genotyping tools are not available for C. muris and C. andersoni, two of the most common gastric Cryptosporidium spp. infecting mammals. In this study, we screened the C. muris whole-genome sequencing data for microsatellite and minisatellite sequences. Among the 13 potential loci (6 microsatellite and 7 minisatellite loci) evaluated by PCR and DNA sequencing, 4 were eventually chosen. DNA sequence analyses of 27 C. muris and 17 C. andersoni DNA preparations showed the presence of 5 to 10 subtypes of C. muris and 1 to 4 subtypes of C. andersoni at each locus. Altogether, 11 C. muris and 7 C. andersoni multilocus sequence typing (MLST) subtypes were detected among the 16 C. muris and 12 C. andersoni specimens successfully sequenced at all four loci. In all analyses, the C. muris isolate (TS03) that originated from an East African mole rat differed significantly from other C. muris isolates, approaching the extent of genetic differences between C. muris and C. andersoni. Thus, an MLST technique was developed for the high-resolution typing of C. muris and C. andersoni. It should be useful for the characterization of the population genetics and transmission of gastric Cryptosporidium spp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980577"}
{"pmid": "20980578", "title": "Temporal characterization of carrot broth-enhanced real-time PCR as an alternative means for rapid detection of Streptococcus agalactiae from prenatal anorectal and vaginal screenings.", "content": "Temporal characterization of carrot broth-enhanced real-time PCR as an alternative means for rapid detection of Streptococcus agalactiae from prenatal anorectal and vaginal screenings. Analysis of overnight carrot broth culture using the BD GeneOhm StrepB assay (carrot broth-enhanced PCR) yields increased sensitivity compared to that of carrot broth culture alone for the detection of Streptococcus agalactiae. We investigated the prospect of reducing the carrot broth incubation time prior to PCR performance. In vitro experimentation demonstrated that carrot broth-enhanced PCR nominally detected 10 CFU S. agalactiae after 4 h of carrot broth incubation with competitive flora. Detection rates improved with inocula of 100 and 1,000 CFU S. agalactiae, with the majority of these aliquots demonstrating detection after 2 h of carrot broth incubation. Carrot broth was prospectively inoculated with clinical vaginal/anorectal swabs, with 500-μl aliquots collected. Early aliquots from 227 specimens were subjected to carrot broth-enhanced PCR (early-aliquot carrot broth-enhanced PCR) in instances of subsequent positive carrot broth culture or positive overnight clinical carrot broth-enhanced PCR. The S. agalactiae detection rate by early-aliquot carrot broth-enhanced PCR (66.1%) exceeded that observed for 227 remnant swabs retrospectively tested by direct swab PCR (56.4%; P=0.03). Early-aliquot carrot broth-enhanced PCR detection rate differences were most pronounced in aliquots from 83 carrot broth aliquots collected after 6 h (84.3%) compared to detection rates from either direct swab PCR of these samples (51.8%; P<0.0002) or early-aliquot carrot broth-enhanced PCR of 144 carrot broth aliquots collected after fewer than 6 h of incubation (55.6%; P<0.0002). Enhanced sensitivity of early-aliquot carrot broth-enhanced PCR versus direct swab PCR suggests that this assay could serve as a surrogate rapid detection method facilitating the prevention of group B streptococcal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980578"}
{"pmid": "20980579", "title": "Improved selective and differential medium for isolation of Escherichia coli O157:H7.", "content": "Improved selective and differential medium for isolation of Escherichia coli O157:H7. GMAC, a modified version of Sorbitol MacConkey medium (SMAC), was produced with a reduced quantity of selective agents and incorporated gentiobiose. GMAC supported a higher recovery rate of heat- or acid-injured Escherichia coli O157:H7 cells than SMAC with cefixime and tellurite (CT-SMAC), while differentiating E. coli O157:H7 from sorbitol-nonfermenting Hafnia alvei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980579"}
{"pmid": "20980580", "title": "Development and evaluation of a rapid influenza diagnostic test for the pandemic (H1N1) 2009 influenza virus.", "content": "Development and evaluation of a rapid influenza diagnostic test for the pandemic (H1N1) 2009 influenza virus. We evaluated a new rapid influenza diagnostic test for the pandemic (H1N1) 2009 influenza virus by using real-time reverse transcription-PCR (rRT-PCR) and viral culture. The sensitivities were 68.5% and 64.5%, and the specificities were 98.4% and 97.6%, respectively. This kit should be used with caution, and negative results should be verified by a confirmative test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980580"}
{"pmid": "20980581", "title": "Quantitative detection of enterotoxigenic Bacteroides fragilis subtypes isolated from children with and without diarrhea.", "content": "Quantitative detection of enterotoxigenic Bacteroides fragilis subtypes isolated from children with and without diarrhea. A rapid real-time PCR (RT-PCR) approach was developed to detect the bft gene subtypes in Bacteroides fragilis isolated from fecal samples. DNA obtained from diarrhea (110) and nondiarrhea (150) samples was evaluated. Subtype 1 was observed in 9 (8.2%) diarrhea and 7 (4.7%) nondiarrhea samples. Subtype 2 was not detected in any DNA samples, and subtype 3 was observed in only 1 diarrhea sample. The presence of the bft-1 gene did not show any statistically significant differences between the groups of children. This technique could be used to evaluate a possible correlation between disease and the presence of B. fragilis enterotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980581"}
{"pmid": "20980583", "title": "Intrinsic coupling between gamma oscillations, neuronal discharges, and slow cortical oscillations during human slow-wave sleep.", "content": "Intrinsic coupling between gamma oscillations, neuronal discharges, and slow cortical oscillations during human slow-wave sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980583"}
{"pmid": "20980582", "title": "Regional spread of Pseudomonas aeruginosa ST357 producing IMP-7 metallo-β-lactamase in Central Europe.", "content": "Regional spread of Pseudomonas aeruginosa ST357 producing IMP-7 metallo-β-lactamase in Central Europe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980582"}
{"pmid": "20980584", "title": "Vibrotactile masking experiments reveal accelerated somatosensory processing in congenitally blind braille readers.", "content": "Vibrotactile masking experiments reveal accelerated somatosensory processing in congenitally blind braille readers. Braille reading is a demanding task that requires the identification of rapidly varying tactile patterns. During proficient reading, neighboring characters impact the fingertip at ∼100 ms intervals, and adjacent raised dots within a character at 50 ms intervals. Because the brain requires time to interpret afferent sensorineural activity, among other reasons, tactile stimuli separated by such short temporal intervals pose a challenge to perception. How, then, do proficient Braille readers successfully interpret inputs arising from their fingertips at such rapid rates? We hypothesized that somatosensory perceptual consolidation occurs more rapidly in proficient Braille readers. If so, Braille readers should outperform sighted participants on masking tasks, which demand rapid perceptual processing, but would not necessarily outperform the sighted on tests of simple vibrotactile sensitivity. To investigate, we conducted two-interval forced-choice vibrotactile detection, amplitude discrimination, and masking tasks on the index fingertips of 89 sighted and 57 profoundly blind humans. Sighted and blind participants had similar unmasked detection (25 ms target tap) and amplitude discrimination (compared with 100 μm reference tap) thresholds, but congenitally blind Braille readers, the fastest readers among the blind participants, exhibited significantly less masking than the sighted (masker, 50 Hz, 50 μm; target-masker delays, ±50 and ±100 ms). Indeed, Braille reading speed correlated significantly and specifically with masking task performance, and in particular with the backward masking decay time constant. We conclude that vibrotactile sensitivity is unchanged but that perceptual processing is accelerated in congenitally blind Braille readers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980584"}
{"pmid": "20980585", "title": "Effects of synaptic modulation on beta-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice.", "content": "Effects of synaptic modulation on beta-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice. Accumulation of β-amyloid (Aβ) and loss of synapses are hallmarks of Alzheimer's disease (AD). How synaptic activity relates to Aβ accumulation and loss of synapses is a current topic of major interest. Synaptic activation promotes Aβ secretion, and chronic reduction of synaptic activity reduced Aβ plaques in an AD transgenic mouse model. This suggested beneficial effects of reducing synaptic activity in AD. We now show that reduced synaptic activity causes detrimental effects on synapses and memory despite reducing plaques using two different models of chronic synaptic inhibition: deafferentation of the barrel cortex and administration of benzodiazepine. An interval of prolonged synaptic inhibition exacerbated loss of synaptophysin compared with synaptically more active brain in AD transgenic but not wild-type mice. Furthermore, an interval of benzodiazepine treatment, followed by a washout period, exacerbated memory impairment in AD transgenic mice. Exacerbation of synaptic and behavioral abnormalities occurred in the setting of reduced Aβ plaques but elevated intraneuronal Aβ immunoreactivity. These data support beneficial effects of synaptic activation on Aβ-related synaptic and behavioral impairment in AD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980585"}
{"pmid": "20980586", "title": "Decision threshold modulation in the human brain.", "content": "Decision threshold modulation in the human brain. Perceptual decisions are made when sensory evidence accumulated over time reaches a decision threshold. Because decisions are also guided by prior information, one important factor that is likely to shape how a decision is adaptively tuned to its context is the predictability of forthcoming events. However, little is known about the mechanisms underlying this contextual regulation of the perceptual decision-making process. Mathematical models of decision making predict two possible mechanisms supporting this regulation: an adjustment of the distance to the decision threshold, which leads to a change in the amount of accumulated evidence required to make a decision, or a gain control of the sensory evidence, leading to a change in the slope of the sensory evidence accumulation. Here, we show that predictability of the forthcoming event reduces the distance to the threshold of the decision. Then, combining model-driven fMRI and the framework of information theory, we show that the anterior cingulate cortex (ACC) adjusts the distance to the decision threshold in proportion to the current amount of predictive information and that the dorsolateral cortex (DLPFC) codes the accumulation of sensory evidence. Moreover, the information flow from the ACC to the DLPFC region that accumulates sensory evidence increases when optimal adjustment of the distance to the threshold requires more complex computations, reflecting the increased weight of ACC's regulation signals in the decision process. Our results characterize the respective contributions of the ACC and the DLPFC to contextually optimized decision making.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980586"}
{"pmid": "20980574", "title": "Analyses of pediatric isolates of Cryptococcus neoformans from South Africa.", "content": "Analyses of pediatric isolates of Cryptococcus neoformans from South Africa. Compared to the incidence in adults, cryptococcosis is inexplicably rare among children, even in sub-Saharan Africa, which has the highest prevalence of coinfection with HIV and Cryptococcus neoformans. To explore any mycological basis for this age-related difference in the incidence of cryptococcosis, we investigated isolates of C. neoformans recovered from pediatric and adult patients during a 2-year period in South Africa. From reports to the Group for Enteric, Respiratory, and Meningeal Disease Surveillance in South Africa (GERMS-SA), we reviewed all cases of cryptococcosis in 2005 and 2006. We analyzed one isolate of C. neoformans from each of 82 pediatric patients (<15 years of age) and determined the multilocus sequence type (ST), mating type, ploidy, and allelic profile. This sample included isolates of all three molecular types of serotype A or C. neoformans var. grubii (molecular types VNI, VNII, and VNB) and one AD hybrid. Seventy-seven (94%) of the strains possessed the MATα mating type allele, and five were MATa. Seventy-five (91%) were haploid, and seven were diploid. A total of 24 different STs were identified. The ratios of each mating type and the proportion of haploids were comparable to those for the isolates that were obtained from 86 adult patients during the same period. Notably, the most prevalent pediatric ST was significantly associated with male patients. Overall, these pediatric isolates exhibited high genotypic diversity. They included a relatively large percentage of diploids and the rarely reported MATa mating type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980574"}
{"pmid": "20980587", "title": "Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A.", "content": "Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A. YAC transgenic mice expressing poly(Q)-expanded full-length huntingtin (mhtt) recapitulate many behavioral and neuropathological features of Huntington disease (HD). We have previously observed a reduction in phosphorylation of mhtt at S421 in the presence of the mutation for HD. In addition, phosphorylation of normal S421-htt is reduced after excitotoxic stimulation of NMDA receptors (NMDARs). To test whether NMDAR stimulation contributes to reduced pS421-htt levels in HD, we determined phosphorylation of htt at Ser421 after NMDA-induced excitotoxicity in neurons from YAC128 mice. Here, we report that the total level of pS421-htt is reduced in YAC128 primary neurons after excitotoxic NMDAR stimulation. Similarly, the total level of pS421-htt is reduced in YAC128 transgenic mice after quinolinic acid injection into the striatum. In contrast, loss of phosphorylation of pS421-htt is prevented in YAC mice that never develop clinical or neuropathological features of HD [the caspase 6-resistant YAC128 transgene (C6R)]. To gain insight into the mechanisms underlying these findings, we determined that the Ser/Thr protein phosphatases PP1 and PP2A dephosphorylate pS421-htt in situ and after excitotoxic stimulation of NMDARs in neurons. Furthermore, increasing the phosphorylation of htt at S421 by blocking PP1 and PP2A activity protects YAC128 striatal neurons from NMDA-induced cell death. These results, together with the observed modulation of pS421-htt levels by dopamine, the reduced expression of PP1 inhibitor Darpp-32 in the striatum of YAC128 mice, and the reduced phosphorylation of PP1 substrate CreB, point to altered regulation of phosphatase activity in HD and highlight enhancing phosphorylation of htt at S421 as a therapeutic target.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980587"}
{"pmid": "20980588", "title": "Control of spatial and feature-based attention in frontoparietal cortex.", "content": "Control of spatial and feature-based attention in frontoparietal cortex. Visual attention selects task-relevant information from scenes to help achieve behavioral goals. Attention can be deployed within multiple domains to select specific spatial locations, features, or objects. Recent evidence has shown that voluntary shifts of attention in multiple domains are consistently associated with transient increases in cortical activity in medial superior parietal lobule, suggesting that this may be the source of a domain-independent control signal that initiates the reconfiguration of attention. To investigate this hypothesis, we used fMRI to measure changes in cortical activation while human subjects shifted attention between spatial locations or between colors at a location. Univariate multiple regression analysis revealed a common, domain-independent transient signal [in posterior parietal cortex (PPC) and prefrontal cortex] time-locked to shifts of attention in both domains. However, multivariate pattern classification conducted on the cortical surface revealed that the spatiotemporal pattern of activity within PPC differed reliably for spatial and feature-based attention shifts. These results suggest that the posterior parietal cortex is a common hub for the control of attention shifts but contains subpopulations of neurons with domain-specific tuning for cognitive control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980588"}
{"pmid": "20980589", "title": "Naked dense bodies provoke depression.", "content": "Naked dense bodies provoke depression. At presynaptic active zones (AZs), the frequently observed tethering of synaptic vesicles to an electron-dense cytomatrix represents a process of largely unknown functional significance. Here, we identified a hypomorphic allele, brpnude, lacking merely the last 1% of the C-terminal amino acids (17 of 1740) of the active zone protein Bruchpilot. In brpnude, electron-dense bodies were properly shaped, though entirely bare of synaptic vesicles. While basal glutamate release was unchanged, paired-pulse and sustained stimulation provoked depression. Furthermore, rapid recovery following sustained release was slowed. Our results causally link, with intramolecular precision, the tethering of vesicles at the AZ cytomatrix to synaptic depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980589"}
{"pmid": "20980591", "title": "Sleep spindle activity is associated with the integration of new memories and existing knowledge.", "content": "Sleep spindle activity is associated with the integration of new memories and existing knowledge. Sleep spindle activity has been associated with improvements in procedural and declarative memory. Here, for the first time, we looked at the role of spindles in the integration of newly learned information with existing knowledge, contrasting this with explicit recall of the new information. Two groups of participants learned novel spoken words (e.g., cathedruke) that overlapped phonologically with familiar words (e.g., cathedral). The sleep group was exposed to the novel words in the evening, followed by an initial test, a polysomnographically monitored night of sleep, and a second test in the morning. The wake group was exposed and initially tested in the morning and spent a retention interval of similar duration awake. Finally, both groups were tested a week later at the same circadian time to control for possible circadian effects. In the sleep group, participants recalled more words and recognized them faster after sleep, whereas in the wake group such changes were not observed until the final test 1 week later. Following acquisition of the novel words, recognition of the familiar words was slowed in both groups, but only after the retention interval, indicating that the novel words had been integrated into the mental lexicon following consolidation. Importantly, spindle activity was associated with overnight lexical integration in the sleep group, but not with gains in recall rate or recognition speed of the novel words themselves. Spindle activity appears to be particularly important for overnight integration of new memories with existing neocortical knowledge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980591"}
{"pmid": "20980590", "title": "Distinct modulatory effects of satiety and sibutramine on brain responses to food images in humans: a double dissociation across hypothalamus, amygdala, and ventral striatum.", "content": "Distinct modulatory effects of satiety and sibutramine on brain responses to food images in humans: a double dissociation across hypothalamus, amygdala, and ventral striatum. We used functional magnetic resonance imaging to explore brain responses to food images in overweight humans, examining independently the impact of a prescan meal (\"satiety\") and the anti-obesity drug sibutramine, a serotonin and noradrenaline reuptake inhibitor. We identified significantly different responses to these manipulations in amygdala, hypothalamus, and ventral striatum. Each region was specifically responsive to high-calorie compared to low-calorie food images. However, the ventral striatal response was attenuated by satiety (but unaffected by sibutramine), while the hypothalamic and amygdala responses were attenuated by drug but unaffected by satiety. Direct assessment of regional interactions confirmed the significance of this double dissociation. We explored the regional responses in greater detail by determining whether they were predictive of eating behavior and weight change. We observed that across the different regions, the individual-specific magnitude of drug- and satiety-induced modulation was associated with both variables: the sibutramine-induced modulation of the hypothalamic response was correlated with the drug's impact on both weight and subsequently measured ad libitum eating. The satiety-induced modulation of striatal response also correlated with subsequent ad libitum eating. These results suggest that hypothalamus and amygdala have roles in the control of food intake that are distinct from those of ventral striatum. Furthermore, they support a regionally specific effect on brain function through which sibutramine exerts its clinical effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980590"}
{"pmid": "20980592", "title": "Visinin-like neuronal calcium sensor proteins regulate the slow calcium-activated afterhyperpolarizing current in the rat cerebral cortex.", "content": "Visinin-like neuronal calcium sensor proteins regulate the slow calcium-activated afterhyperpolarizing current in the rat cerebral cortex. Many neurons in the nervous systems express afterhyperpolarizations that are mediated by a slow calcium-activated potassium current. This current shapes neuronal firing and is inhibited by neuromodulators, suggesting an important role in the regulation of neuronal function. Surprisingly, very little is currently known about the molecular basis for this current or how it is gated by calcium. Recently, the neuronal calcium sensor protein hippocalcin was identified as a calcium sensor for the slow afterhyperpolarizing current in the hippocampus. However, while hippocalcin is very strongly expressed in the hippocampus, this protein shows a relatively restricted distribution in the brain. Furthermore, the genetic deletion of this protein only partly reduces the slow hyperpolarizing current in hippocampus. These considerations question whether hippocalcin can be the sole calcium sensor for the slow afterhyperpolarizing current. Here we use loss of function and overexpression strategies to show that hippocalcin functions as a calcium sensor for the slow afterhyperpolarizing current in the cerebral cortex, an area where hippocalcin is expressed at much lower levels than in hippocampus. In addition we show that neurocalcin δ, but not VILIP-2, can also act as a calcium sensor for the slow afterhyperpolarizing current. Finally we show that hippocalcin and neurocalcin δ both increase the calcium sensitivity of the afterhyperpolarizing current but do not alter its sensitivity to inhibition by carbachol acting through the Gαq-11-PLCβ signaling cascade. These results point to a general role for a subgroup of visinin-like neuronal calcium sensor proteins in the activation of the slow calcium-activated afterhyperpolarizing current.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980592"}
{"pmid": "20980593", "title": "S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development.", "content": "S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development. Precise regulation of cyclin-dependent kinase 5 (Cdk5), a member of the cyclin-dependent kinase family, is critical for proper neuronal development and functions. Cdk5 is activated through its association with the neuron-specific activator p35 or p39. Nonetheless, how its kinase activity is regulated in neurons is not well understood. In this study, we found that Cdk5 activity is regulated by S-nitrosylation, a post-translational modification of protein that affects a plethora of neuronal functions. S-nitrosylation of Cdk5 occurs at Cys83, which is one of the critical amino acids within the ATP-binding pocket of the kinase. Upon S-nitrosylation, Cdk5 exhibits reduced kinase activity, whereas mutation of Cys83 to Ala on Cdk5 renders the kinase refractory to such inhibition. Importantly, S-nitrosylated Cdk5 can be detected in the mouse brain, and blocking the S-nitrosylation of Cdk5 in cultured hippocampal neurons enhances dendritic growth and branching. Together, our findings reveal an important role of S-nitrosylation in regulating Cdk5 kinase activity and dendrite growth in neurons during development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980593"}
{"pmid": "20980595", "title": "A behavioral and neural evaluation of prospective decision-making under risk.", "content": "A behavioral and neural evaluation of prospective decision-making under risk. Making the best choice when faced with a chain of decisions requires a person to judge both anticipated outcomes and future actions. Although economic decision-making models account for both risk and reward in single-choice contexts, there is a dearth of similar knowledge about sequential choice. Classical utility-based models assume that decision-makers select and follow an optimal predetermined strategy, regardless of the particular order in which options are presented. An alternative model involves continuously reevaluating decision utilities, without prescribing a specific future set of choices. Here, using behavioral and functional magnetic resonance imaging (fMRI) data, we studied human subjects in a sequential choice task and use these data to compare alternative decision models of valuation and strategy selection. We provide evidence that subjects adopt a model of reevaluating decision utilities, in which available strategies are continuously updated and combined in assessing action values. We validate this model by using simultaneously acquired fMRI data to show that sequential choice evokes a pattern of neural response consistent with a tracking of anticipated distribution of future reward, as expected in such a model. Thus, brain activity evoked at each decision point reflects the expected mean, variance, and skewness of possible payoffs, consistent with the idea that sequential choice evokes a prospective evaluation of both available strategies and possible outcomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980595"}
{"pmid": "20980594", "title": "Visual representations by cortical somatostatin inhibitory neurons--selective but with weak and delayed responses.", "content": "Visual representations by cortical somatostatin inhibitory neurons--selective but with weak and delayed responses. Somatostatin-expressing inhibitory (SOM) neurons in the sensory cortex consist mostly of Martinotti cells, which project ascending axons to layer 1. Due to their sparse distribution, the representational properties of these neurons remain largely unknown. By two-photon imaging guided cell-attached recordings, we characterized visual response and receptive field (RF) properties of SOM neurons and parvalbumin-expressing inhibitory (PV) neurons genetically labeled in the mouse primary visual cortex. In contrast to PV neurons, SOM neurons exhibit broader spikes, lower spontaneous firing rates, smaller On/Off subfields, and broader ranges of basic RF properties such as On/Off segregation, orientation and direction tunings. Notably, the level of orientation and direction selectivity is comparable to that of excitatory neurons, from weakly-tuned to highly selective, whereas PV neurons are in general unselective. Strikingly, the evoked spiking responses of SOM cells are ∼3- to 5-fold weaker and 20-25 ms delayed compared with those of PV neurons. The onset latency of the latter is consistent with that of inhibitory input to excitatory neurons. These functional differences between SOM and PV neurons exist in both layer 2/3 and 4. Our results suggest that SOM and PV neurons engage in cortical circuits in different manners: while PV neurons provide fast, strong but untuned feedforward inhibition to excitatory neurons, likely serving as a general gain control for the processing of ascending inputs, SOM neurons with their selective but delayed and weak inhibition may provide more specific gating of later arriving intracortical excitatory inputs on the distal dendrites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980594"}
{"pmid": "20980596", "title": "The parafascicular thalamic nucleus concomitantly influences behavioral flexibility and dorsomedial striatal acetylcholine output in rats.", "content": "The parafascicular thalamic nucleus concomitantly influences behavioral flexibility and dorsomedial striatal acetylcholine output in rats. Recent evidence suggests that a circuit involving the centromedian-parafascicular (Pf) thalamus and basal ganglia is critical for a shift away from biased actions. In particular, excitatory input from the Pf onto striatal cholinergic neurons may facilitate behavioral flexibility. Accumulating evidence indicates that an endogenous increase in dorsomedial striatal acetylcholine (ACh) output enhances behavioral flexibility. The present experiments investigated whether the rat (Rattus norvegicus) Pf supports flexibility during reversal learning, in part, by modifying dorsomedial striatal ACh output. This was determined first by examining the effects of Pf inactivation, through infusion of the GABA agonists baclofen and muscimol, on place acquisition and reversal learning. Additional experiments examined Pf inactivation on dorsomedial striatal ACh output during reversal learning and a resting condition. Behavioral testing was performed in a cross-maze. In vivo microdialysis combined with HPLC/electrochemical detection was used to sample ACh from the dorsomedial striatum. Pf inactivation selectively impaired reversal learning in a dose-dependent manner. A subsequent study showed that an increase in dorsomedial striatal ACh efflux (∼30% above basal levels) during reversal learning was blocked by Pf inactivation, which concomitantly impaired reversal learning. In the resting condition, a dose of baclofen and muscimol that blocked a behaviorally induced increase in dorsomedial striatal ACh output did not reduce basal ACh efflux. Together, the present findings indicate that the Pf is an intralaminar thalamic nucleus critical for behavioral flexibility, in part, by directly affecting striatal ACh output under conditions that require a shift in choice patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980596"}
{"pmid": "20980597", "title": "Expectation-driven changes in cortical functional connectivity influence working memory and long-term memory performance.", "content": "Expectation-driven changes in cortical functional connectivity influence working memory and long-term memory performance. Expectations generated by predictive cues increase the efficiency of perceptual processing for complex stimuli (e.g., faces, scenes); however, the impact this has on working memory (WM) and long-term memory (LTM) has not yet been investigated. Here, healthy young adults performed delayed-recognition tasks that differed only in stimulus category expectations, while behavioral and functional magnetic resonance imaging data were collected. Univariate and functional-connectivity analyses were used to examine expectation-driven, prestimulus neural modulation, networks that regulate this modulation, and subsequent memory performance. Results revealed that predictive category cueing was associated with both enhanced WM and LTM for faces, as well as baseline activity shifts in a face-selective region of the visual association cortex [i.e., fusiform face area (FFA)]. In addition, the degree of functional connectivity between FFA and right inferior frontal junction (IFJ), middle frontal gyrus (MFG), inferior frontal gyrus, and intraparietal sulcus correlated with the magnitude of prestimulus activity modulation in the FFA. In an opposing manner, prestimulus connectivity between FFA and posterior cingulate cortex, a region of the default network, negatively correlated with FFA activity modulation. Moreover, whereas FFA connectivity with IFJ and the precuneus predicted enhanced expectation-related WM performance, FFA connectivity with MFG predicted LTM improvements. These findings suggest a model of expectancy-mediated neural biasing, in which a single node (e.g., FFA) can be dynamically linked or disconnected from different brain regions depending on prestimulus expectations, and the strength of distinct connections is associated with WM or LTM benefits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980597"}
{"pmid": "20980599", "title": "Changes of meningeal excitability mediated by corticotrigeminal networks: a link for the endogenous modulation of migraine pain.", "content": "Changes of meningeal excitability mediated by corticotrigeminal networks: a link for the endogenous modulation of migraine pain. Alterations in cortical excitability are implicated in the pathophysiology of migraine. However, the relationship between cortical spreading depression (CSD) and headache has not been fully elucidated. We aimed to identify the corticofugal networks that directly influence meningeal nociception in the brainstem trigeminocervical complex (Sp5C) of the rat. Cortical areas projecting to the brainstem were first identified by retrograde tracing from Sp5C areas that receive direct meningeal inputs. Anterograde tracers were then injected into these cortical areas to determine the precise pattern of descending axonal terminal fields in the Sp5C. Descending cortical projections to brainstem areas innervated by the ophthalmic branch of the trigeminal nerve originate contralaterally from insular (Ins) and primary somatosensory (S1) cortices and terminate in laminae I-II and III-V of the Sp5C, respectively. In another set of experiments, electrophysiological recordings were simultaneously performed in Ins, S1 or primary visual cortex (V1), and Sp5C neurons. KCl was microinjected into such cortical areas to test the effects of CSD on meningeal nociception. CSD initiated in Ins and S1 induced facilitation and inhibition of meningeal-evoked responses, respectively. CSD triggered in V1 affects differently Ins and S1 cortices, enhancing or inhibiting meningeal-evoked responses of Sp5C, without affecting cutaneous-evoked nociceptive responses. Our data suggest that \"top-down\" influences from lateralized areas within Ins and S1 selectively affect interoceptive (meningeal) over exteroceptive (cutaneous) nociceptive inputs onto Sp5C. Such corticofugal influences could contribute to the development of migraine pain in terms of both topographic localization and pain tuning during an attack.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980599"}
{"pmid": "20980598", "title": "Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils.", "content": "Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils. Nonfibrillar, water-soluble low-molecular weight assemblies of the amyloid β-protein (Aβ) are believed to play an important role in Alzheimer's disease (AD). Aqueous extracts of human brain contain Aβ assemblies that migrate on SDS-polyacrylamide gels and elute from size exclusion as dimers (∼8 kDa) and can block long-term potentiation and impair memory consolidation in the rat. Such species are detected specifically and sensitively in extracts of Alzheimer brain suggesting that SDS-stable dimers may be the basic building blocks of AD-associated synaptotoxic assemblies. Consequently, understanding the structure and properties of Aβ dimers is of great interest. In the absence of sufficient brain-derived dimer to facilitate biophysical analysis, we generated synthetic dimers designed to mimic the natural species. For this, Aβ(1-40) containing cysteine in place of serine 26 was used to produce disulphide cross-linked dimer, (AβS26C)2. Such dimers had no detectable secondary structure, produced an analytical ultracentrifugation profile consistent for an ∼8.6 kDa protein, and had no effect on hippocampal long-term potentiation (LTP). However, (AβS26C)2 aggregated more rapidly than either AβS26C or wild-type monomers and formed parastable β-sheet rich, thioflavin T-positive, protofibril-like assemblies. Whereas wild-type Aβ aggregated to form typical amyloid fibrils, the protofibril-like structures formed by (AβS26C)2 persisted for prolonged periods and potently inhibited LTP in mouse hippocampus. These data support the idea that Aβ dimers may stabilize the formation of fibril intermediates by a process distinct from that available to Aβ monomer and that higher molecular weight prefibrillar assemblies are the proximate mediators of Aβ toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980598"}
{"pmid": "20980600", "title": "Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum.", "content": "Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum. The Abl family nonreceptor tyrosine kinases, consisting of closely related Abl and Arg (Abl-related gene), play essential roles in mouse neurulation, but their functions in the subsequent development of CNS are poorly understood. Here, we show that conditional deletion of Abl in precursors of neurons and glia on an Arg knock-out background leads to striking cerebellar malformations, including defects in anterior cerebellar morphogenesis, granule cell ectopia, and hypoplasia. Time course analyses reveal that the abnormal anterior cerebellar foliation results from local disruptions of the basement membrane (BM) located between radial glial endfeet and the meninges during embryonic cerebellar development. Granule cell ectopia and hypoplasia are also associated with the breaches in the BM and abnormal Bergmann glial networks during postnatal cerebellar development. In vitro culture experiments indicate that Abl/Arg-deficient granule cells can interact with glial processes and proliferate normally in response to sonic hedgehog compared to cells isolated from control mice. Consistent with these findings, selective ablation of Abl family kinases in cerebellar granule cells alone does not cause any abnormality, suggesting that deletion of Abl/Arg from glia is likely required for the mutant phenotype. Together, these results provide compelling evidence that Abl and Arg play key redundant roles in BM maintenance and cortical lamination in the cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980600"}
{"pmid": "20980601", "title": "Presynaptic BDNF promotes postsynaptic long-term potentiation in the dorsal striatum.", "content": "Presynaptic BDNF promotes postsynaptic long-term potentiation in the dorsal striatum. Brain-derived neurotrophic factor (BDNF) facilitates the formation of long-term potentiation (LTP) in hippocampus, but whether this involves release from presynaptic versus postsynaptic pools is unclear. We therefore tested whether BDNF is essential for LTP in dorsal striatum, a structure in which the neurotrophin is present only in afferent terminals. Whole-cell recordings were collected from medium spiny neurons in striatal slices prepared from adult mice. High-frequency stimulation (HFS) of neocortical afferents produced a rapid and stable NMDA receptor-dependent potentiation. The ratio of AMPA to NMDA receptor-mediated components of the EPSPs was substantially increased after inducing potentiation, suggesting that the response enhancement involved postsynaptic changes. In accord with this, paired-pulse response ratios, a measure of transmitter release kinetics, were reduced by elevated calcium but not by LTP. Infusion of the BDNF scavenger TrkB-Fc blocked the formation of potentiation, beginning with the second minute after HFS, without reducing responses to HFS. These results suggest that presynaptic pools of BDNF can act within 2 min of HFS to support the formation of a postsynaptic form of LTP in striatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980601"}
{"pmid": "20980602", "title": "Drosophila glial glutamate transporter Eaat1 is regulated by fringe-mediated notch signaling and is essential for larval locomotion.", "content": "Drosophila glial glutamate transporter Eaat1 is regulated by fringe-mediated notch signaling and is essential for larval locomotion. In the mammalian CNS, glial cells expressing excitatory amino acid transporters (EAATs) tightly regulate extracellular glutamate levels to control neurotransmission and protect neurons from excitotoxic damage. Dysregulated EAAT expression is associated with several CNS pathologies in humans, yet mechanisms of EAAT regulation and the importance of glutamate transport for CNS development and function in vivo remain incompletely understood. Drosophila is an advanced genetic model with only a single high-affinity glutamate transporter termed Eaat1. We found that Eaat1 expression in CNS glia is regulated by the glycosyltransferase Fringe, which promotes neuron-to-glia signaling through the Delta-Notch ligand-receptor pair during embryogenesis. We made Eaat1 loss-of-function mutations and found that homozygous larvae could not perform the rhythmic peristaltic contractions required for crawling. We found no evidence for excitotoxic cell death or overt defects in the development of neurons and glia, and the crawling defect could be induced by postembryonic inactivation of Eaat1. Eaat1 fully rescued locomotor activity when expressed in only a limited subpopulation of glial cells situated near potential glutamatergic synapses within the CNS neuropil. Eaat1 mutants had deficits in the frequency, amplitude, and kinetics of synaptic currents in motor neurons whose rhythmic patterns of activity may be regulated by glutamatergic neurotransmission among premotor interneurons; similar results were seen with pharmacological manipulations of glutamate transport. Our findings indicate that Eaat1 expression is promoted by Fringe-mediated neuron-glial communication during development and suggest that Eaat1 plays an essential role in regulating CNS neural circuits that control locomotion in Drosophila.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980602"}
{"pmid": "20980603", "title": "Two distinct modes of PERIOD recruitment onto dCLOCK reveal a novel role for TIMELESS in circadian transcription.", "content": "Two distinct modes of PERIOD recruitment onto dCLOCK reveal a novel role for TIMELESS in circadian transcription. Negative transcriptional feedback loops are a core feature of eukaryotic circadian clocks and are based on rhythmic interactions between clock-specific repressors and transcription factors. In Drosophila, the repression of dCLOCK (dCLK)-CYCLE (CYC) transcriptional activity by dPERIOD (dPER) is critical for driving circadian gene expression. Although growing lines of evidence indicate that circadian repressors such as dPER function, at least partly, as molecular bridges that facilitate timely interactions between other regulatory factors and core clock transcription factors, how dPER interacts with dCLK-CYC to promote repression is not known. Here, we identified a small conserved region on dPER required for binding to dCLK, termed CBD (for dCLK binding domain). In the absence of the CBD, dPER is unable to stably associate with dCLK and inhibit the transcriptional activity of dCLK-CYC in a simplified cell culture system. CBD is situated in close proximity to a region that interacts with other regulatory factors such as the DOUBLETIME kinase, suggesting that complex architectural constraints need to be met to assemble repressor complexes. Surprisingly, when dPER missing the CBD (dPER(ΔCBD)) was evaluated in flies the clock mechanism was operational, albeit with longer periods. Intriguingly, the interaction between dPER(ΔCBD) and dCLK is TIM-dependent and modulated by light, revealing a novel and unanticipated in vivo role for TIM in circadian transcription. Finally, dPER(ΔCBD) does not provoke the daily hyperphosphorylation of dCLK, indicating that direct interactions between dPER and dCLK are necessary for the dCLK phosphorylation program but are not required for other aspects of dCLK regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980603"}
{"pmid": "20980604", "title": "Thermally active TRPV1 tonically drives central spontaneous glutamate release.", "content": "Thermally active TRPV1 tonically drives central spontaneous glutamate release. Central synapses spontaneously release neurotransmitter at low rates. In the brainstem, cranial visceral afferent terminals in caudal solitary tract nucleus (NTS) display pronounced, activity-dependent, asynchronous release of glutamate and this extra release depends on TRPV1 receptors (TRPV1+). Asynchronous release is absent for afferents lacking TRPV1 (TRPV1-) and resting EPSC frequency was greater in TRPV1+. Here, we studied this basal activity difference by assessing thermal sensitivity of spontaneous and miniature synaptic events in TRPV1+ and TRPV1- second-order NTS neurons. The spontaneous EPSC rate decreased when temperature was decreased, increased steeply between 30 and 42°C only in TRPV1+ neurons, and was calcium-dependent. TRPV1-specific antagonist SB366791, but not TTX, strongly attenuated thermal responses. Temperature changes failed to alter EPSC frequency in TRPV1- neurons. EPSC amplitudes and decay kinetics changed little with temperature. IPSCs in these second-order NTS neurons were unaltered by temperature. Such results suggest that activated, presynaptic TRPV1+ receptors trigger continuous resting release of glutamate vesicles at physiological temperatures only in capsaicin-responsive terminals. In mechanically isolated individual neurons harvested from medial NTS, increases in temperature increased the rate of glutamate release only in TRPV1+ neurons, whereas IPSC rates were unaffected. Cadmium failed to block thermal increases in glutamate release, suggesting that calcium entry through TRPV1 channels may trigger glutamate release independently of voltage-activated calcium channels. Together, our findings indicate a new form of afferent signaling in which TRPV1 channels within central terminals of peripheral afferents tonically generate glutamate release in NTS at 37°C in the absence of afferent action potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980604"}
{"pmid": "20980605", "title": "Oligodendrocyte myelin glycoprotein does not influence node of ranvier structure or assembly.", "content": "Oligodendrocyte myelin glycoprotein does not influence node of ranvier structure or assembly. Oligodendrocyte myelin glycoprotein (OMgp) is expressed by both neurons and oligodendrocytes in the CNS. It has been implicated in growth cone collapse and neurite outgrowth inhibition by signaling through the Nogo receptor and paired Ig-like receptor B (PirB). OMgp was also reported to be an extracellular matrix (ECM) protein surrounding CNS nodes of Ranvier and proposed to function as (1) an inhibitor of nodal collateral sprouting and (2) an important contributor to proper nodal and paranodal architecture. However, we show here that the anti-OMgp antiserum used in previous studies to define the functions of OMgp at nodes is not specific. Among all reported nodal ECM components, the antiserum exhibited strong cross-reactivity against versican V2 isoform, a chondroitin sulfate proteoglycan. Furthermore, the OMgp antiserum labeled OMgp-null nodes, but not nodes from versican V2-deficient mice, and preadsorption of the OMgp antiserum with recombinant versican V2 blocked nodal labeling. Analysis of CNS nodes in OMgp-null mice failed to reveal any nodal or paranodal defects, or increased nodal collateral sprouting, indicating that OMgp does not participate in CNS node of Ranvier assembly or maintenance. We successfully identified a highly specific anti-OMgp antibody and observed OMgp staining in white matter only after initiation of myelination. OMgp immunoreactivity decorated the surface of mature myelinated axons, but was excluded from compact myelin and nodes. Together, our results strongly argue against the nodal localization of OMgp and its proposed functions at nodes, and reveal OMgp's authentic localization relative to nodes and myelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980605"}
{"pmid": "20980606", "title": "Escitalopram enhances the association of serotonin-1A autoreceptors to heteroreceptors in anxiety disorders.", "content": "Escitalopram enhances the association of serotonin-1A autoreceptors to heteroreceptors in anxiety disorders. Selective serotonin reuptake inhibitors (SSRIs) represent one of the most common treatment options in major depression and anxiety disorders. By blocking the serotonin transporter, SSRIs modulate serotonergic neurotransmission as well as the function of autoreceptors and heteroreceptors. However, treatment-induced changes on a network level primarily remain unknown. Thus, we evaluated the association between serotonin-1A (5-HT1A) autoreceptors and heteroreceptors before and after SSRIs. Twenty-one patients with anxiety disorders underwent positron emission tomography using [carbonyl-11C]WAY-100635 before and after 12 weeks of escitalopram treatment; 15 of them completed the study protocol. Additionally, 36 drug-naive healthy controls were measured once. The 5-HT1A receptor binding potential (BPND) was quantified for the dorsal raphe nucleus (DRN) using a region-of-interest approach and for the entire brain by calculating parametric maps. Voxel-wise linear regression was applied between DRN autoreceptor and whole-brain heteroreceptor 5-HT1A BPND. Consistent with previous observations, healthy subjects showed widespread positive correlations of 5-HT1A BPND between autoreceptors and heteroreceptors. Comparing patients before versus after escitalopram treatment revealed enhanced associations of autoreceptor-to-heteroreceptor 5-HT1A BPND within the amygdala and hippocampus (R2=0.21-0.28 vs 0.49-0.81; p<0.05-0.001). In contrast, no significant SSRI-induced changes were found for correlations of heteroreceptor-to-heteroreceptor 5-HT1A BPND between several limbic regions. This interregional approach suggests a treatment-induced reinforcement of the association of 5-HT1A binding between autoreceptors and heteroreceptors specifically in areas involved in anxiety disorders. These findings provide complementary information about treatment effects on a network level and confirm the central role of the DRN as a prime regulatory area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980606"}
{"pmid": "20980608", "title": "Nucleus accumbens-derived glial cell line-derived neurotrophic factor is a retrograde enhancer of dopaminergic tone in the mesocorticolimbic system.", "content": "Nucleus accumbens-derived glial cell line-derived neurotrophic factor is a retrograde enhancer of dopaminergic tone in the mesocorticolimbic system. Spontaneous firing of ventral tegmental area (VTA) dopamine (DA) neurons provides ambient levels of DA in target areas such as the nucleus accumbens (NAc) and the prefrontal cortex (PFC). Here we report that the glial cell line-derived neurotrophic factor (GDNF), produced in one target region, the NAc, is retrogradely transported by DA neurons to the VTA where the growth factor positively regulates the spontaneous firing activity of both NAc- and PFC-projecting DA neurons in a mechanism that requires the activation of the mitogen-activated protein kinase (MAPK) pathway. We also show that the consequence of GDNF-mediated activation of the MAPK signaling cascade in the VTA is an increase in DA overflow in the NAc. Together, these results demonstrate that NAc-produced GDNF serves as a retrograde enhancer that upregulates the activity of the mesocorticolimbic DA system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980608"}
{"pmid": "20980607", "title": "Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction.", "content": "Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction. Although the Schwann cell basement membrane (BM) is required for normal Schwann cell terminal differentiation, the role of BM-associated collagens in peripheral nerve maturation is poorly understood. Collagen XV is a BM zone component strongly expressed in peripheral nerves, and we show that its absence in mice leads to loosely packed axons in C-fibers and polyaxonal myelination. The simultaneous lack of collagen XV and another peripheral nerve component affecting myelination, laminin α4, leads to severely impaired radial sorting and myelination, and the maturation of the nerve is permanently compromised, contrasting with the slow repair observed in Lama4-/- single knock-out mice. Moreover, the Col15a1-/-;Lama4-/- double knock-out (DKO) mice initially lack C-fibers and, even over 1 year of age have only a few, abnormal C-fibers. The Lama4-/- knock-out results in motor and tactile sensory impairment, which is exacerbated by a simultaneous Col15a1-/- knock-out, whereas sensitivity to heat-induced pain is increased in the DKO mice. Lack of collagen XV results in slower sensory nerve conduction, whereas the Lama4-/- and DKO mice exhibit increased sensory nerve action potentials and decreased compound muscle action potentials; x-ray diffraction revealed less mature myelin in the sciatic nerves of the latter than in controls. Ultrastructural analyses revealed changes in the Schwann cell BM in all three mutants, ranging from severe (DKO) to nearly normal (Col15a1-/-). Collagen XV thus contributes to peripheral nerve maturation and C-fiber formation, and its simultaneous deletion from neural BM zones with laminin α4 leads to a DKO phenotype distinct from those of both single knock-outs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980607"}
{"pmid": "20980609", "title": "Brain-derived neurotrophic factor mediates non-cell-autonomous regulation of sensory neuron position and identity.", "content": "Brain-derived neurotrophic factor mediates non-cell-autonomous regulation of sensory neuron position and identity. During development, neurons migrate considerable distances to reside in locations that enable their individual functional roles. Whereas migration mechanisms have been extensively studied, much less is known about how neurons remain in their ideal locations. We sought to identify factors that maintain the position of postmigratory dorsal root ganglion neurons, neural crest derivatives for which migration and final position play an important developmental role. We found that an early developing population of sensory neurons maintains the position of later born dorsal root ganglia neurons in an activity-dependent manner. Further, inhibiting or increasing the function of brain-derived neurotrophic factor induces or prevents, respectively, migration of dorsal root ganglia neurons out of the ganglion to locations where they acquire a new identity. Overall, the results demonstrate that neurotrophins mediate non-cell-autonomous maintenance of position and thereby the identity of differentiated neurons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980609"}
{"pmid": "20980610", "title": "Specialization of binaural responses in ventral auditory cortices.", "content": "Specialization of binaural responses in ventral auditory cortices. Accurate orientation to sound under challenging conditions requires auditory cortex, but it is unclear how spatial attributes of the auditory scene are represented at this level. Current organization schemes follow a functional division whereby dorsal and ventral auditory cortices specialize to encode spatial and object features of sound source, respectively. However, few studies have examined spatial cue sensitivities in ventral cortices to support or reject such schemes. Here Fourier optical imaging was used to quantify best frequency responses and corresponding gradient organization in primary (A1), anterior, posterior, ventral (VAF), and suprarhinal (SRAF) auditory fields of the rat. Spike rate sensitivities to binaural interaural level difference (ILD) and average binaural level cues were probed in A1 and two ventral cortices, VAF and SRAF. Continuous distributions of best ILDs and ILD tuning metrics were observed in all cortices, suggesting this horizontal position cue is well covered. VAF and caudal SRAF in the right cerebral hemisphere responded maximally to midline horizontal position cues, whereas A1 and rostral SRAF responded maximally to ILD cues favoring more eccentric positions in the contralateral sound hemifield. SRAF had the highest incidence of binaural facilitation for ILD cues corresponding to midline positions, supporting current theories that auditory cortices have specialized and hierarchical functional organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980610"}
{"pmid": "20980612", "title": "Locus ceruleus and anterior cingulate cortex sustain wakefulness in a novel environment.", "content": "Locus ceruleus and anterior cingulate cortex sustain wakefulness in a novel environment. Locus ceruleus (LC) neuronal activity is correlated with the waking state, yet LC lesions produce only minor alterations in daily wakefulness. Here, we report that sustained elevations in neurobehavioral and EEG arousal in response to exposure to an environment with novel stimuli, including social interaction, are prevented by selective chemical lesions of the LC in rats. Similar results are seen when the anterior cingulate cortex (ACC), which receives especially dense LC innervation, is selectively denervated of LC input or is ablated by the cell-specific neurotoxin ibotenic acid. Anterograde tracing combined with tyrosine hydroxylase immunohistochemistry demonstrates ACC terminals in apposition with the distal dendrites of LC neurons. Our data implicate the ACC as both a source of input to the LC as well as one of its targets and suggests that the two structures engage in a dialog that may provide a critical neurobiological substrate for sustained attention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980612"}
{"pmid": "20980611", "title": "Activity of red nucleus neurons in the cat during postural corrections.", "content": "Activity of red nucleus neurons in the cat during postural corrections. The dorsal-side-up body posture in standing quadrupeds is maintained by the postural system, which includes spinal and supraspinal mechanisms driven by somatosensory inputs from the limbs. A number of descending tracts can transmit supraspinal commands for postural corrections. The first aim of this study was to understand whether the rubrospinal tract participates in their transmission. We recorded activity of red nucleus neurons (RNNs) in the cat maintaining balance on the periodically tilting platform. Most neurons were identified as rubrospinal ones. It was found that many RNNs were profoundly modulated by tilts, suggesting that they transmit postural commands. The second aim of this study was to examine the contribution of sensory inputs from individual limbs to posture-related RNN modulation. Each RNN was recorded during standing on all four limbs, as well as when two or three limbs were lifted from the platform and could not signal platform displacements. By comparing RNN responses in different tests, we found that the amplitude and phase of responses in the majority of RNNs were determined primarily by sensory input from the corresponding (fore or hind) contralateral limb, whereas inputs from other limbs made a much smaller contribution to RNN modulation. These findings suggest that the rubrospinal system is primarily involved in the intralimb postural coordination, i.e., in the feedback control of the corresponding limb and, to a lesser extent, in the interlimb coordination. This study provides a new insight into the formation of supraspinal motor commands for postural corrections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980611"}
{"pmid": "20980613", "title": "Differential contributions of the primate ventrolateral prefrontal and orbitofrontal cortex to serial reversal learning.", "content": "Differential contributions of the primate ventrolateral prefrontal and orbitofrontal cortex to serial reversal learning. The discrimination reversal paradigm is commonly used to measure a subject's ability to adapt their behavior according to changes in stimulus-reward contingencies. Human functional neuroimaging studies have demonstrated activations in the lateral orbitofrontal cortex (OFC) and the inferior frontal gyrus (IFG) in subjects performing this task. Excitotoxic lesions of analogous regions in marmosets have revealed, however, that although the OFC is indeed critical for reversal learning, ventrolateral prefrontal cortex (VLPFC) (analogous to IFG) is not, contributing instead to higher order processing, such as that required in attentional set-shifting and strategy transfer. One major difference between the marmoset and human studies has been the level of training subjects received in reversal learning, being far greater in the latter. Since exposure to repeated contingency changes, as occurs in serial reversal learning, is likely to trigger the development of higher order, rule-based strategies, we hypothesized a critical role of the marmoset VLPFC in performance of a serial reversal learning paradigm. After extensive training in reversal learning, marmosets received an excitotoxic lesion of the VLPFC, OFC, or a sham control procedure. In agreement with our prediction, postsurgery, VLPFC lesioned animals were impaired in performing a series of discrimination reversals, but only when novel visual stimuli were introduced. In contrast, OFC lesioned animals were impaired regardless of whether the visual stimuli were the same or different from those used during presurgery training. Together, these data demonstrate the heterogeneous but interrelated involvement of primate OFC and VLPFC in the performance of serial reversal learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980613"}
{"pmid": "20980615", "title": "Intracellular recordings reveal novel features of neurons that code interaural intensity disparities in the inferior colliculus.", "content": "Intracellular recordings reveal novel features of neurons that code interaural intensity disparities in the inferior colliculus. Many cells in the inferior colliculus (IC) are excited by contralateral and inhibited by ipsilateral stimulation and are thought to be important for sound localization. These excitatory-inhibitory (EI) cells comprise a diverse group, even though they exhibit a common binaural response property. Previous extracellular studies showed the diversity results from different circuits that generate the same EI property among the IC population, where some inherit the property from a lower nucleus, some are formed de novo in the IC, and others inherit EI features that are modified by inhibitory circuits. Here we evaluated the differential circuitry by recording inputs (postsynaptic potentials) and outputs (spikes) with in vivo whole-cell recordings from the IC of awake Mexican free-tailed bats. We show that in a minority of EI cells, either they inherited their binaural property from a lower binaural nucleus or the EI property was created in the IC via inhibitory projections from the ipsilateral ear, features consistent with those observed in extracellular studies. However, in a majority of EI cells, ipsilateral signals evoked subthreshold EPSPs that behaved paradoxically in that EPSP amplitudes increased with intensity, even though binaural signals with the same ipsilateral intensities generated progressively greater spike suppressions. We propose circuitry that can account for the responses we observed and suggest that the ipsilaterally evoked EPSPs could influence the responsiveness of IC cells to dynamic signals with interaural intensity disparities that change over time, such as moving sound sources or multiple sounds that occur in complex acoustic environments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980615"}
{"pmid": "20980616", "title": "Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB.", "content": "Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB. The molecular mechanisms underlying stress- and drug-induced neuronal adaptations are incompletely understood. One molecule implicated in such adaptations is ΔFosB, a transcription factor that accumulates in the rodent nucleus accumbens (NAc), a key brain reward region, in response to either chronic stress or repeated exposure to drugs of abuse. The upstream transcriptional mechanisms controlling ΔFosB induction by these environmental stimuli remain elusive. Here, we identify the activity-dependent transcription factor, serum response factor (SRF), as a novel upstream mediator of stress-, but not cocaine-, induced ΔFosB. SRF is downregulated in NAc of both depressed human patients and in mice chronically exposed to social defeat stress. This downregulation of SRF is absent in resilient animals. Through the use of inducible mutagenesis, we show that stress-mediated induction of ΔFosB, which occurs predominantly in resilient mice, is dependent on SRF expression in this brain region. Furthermore, NAc-specific genetic deletion of SRF promotes a variety of prodepressant- and proanxiety-like phenotypes and renders animals more sensitive to the deleterious effects of chronic stress. In contrast, we demonstrate that SRF does not play a role in ΔFosB accumulation in NAc in response to chronic cocaine exposure. Furthermore, NAc-specific knock-out of SRF has no effect on cocaine-induced behaviors, indicating that chronic social defeat stress and repeated cocaine exposure regulate ΔFosB accumulation and behavioral sensitivity through independent mechanisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980616"}
{"pmid": "20980614", "title": "Distinct functions of glial and neuronal dystroglycan in the developing and adult mouse brain.", "content": "Distinct functions of glial and neuronal dystroglycan in the developing and adult mouse brain. Cobblestone (type II) lissencephaly and mental retardation are characteristic features of a subset of congenital muscular dystrophies that include Walker-Warburg syndrome, muscle-eye-brain disease, and Fukuyama-type congenital muscular dystrophy. Although the majority of clinical cases are genetically undefined, several causative genes have been identified that encode known or putative glycosyltransferases in the biosynthetic pathway of dystroglycan. Here we test the effects of brain-specific deletion of dystroglycan, and show distinct functions for neuronal and glial dystroglycan. Deletion of dystroglycan in the whole brain produced glial/neuronal heterotopia resembling the cerebral cortex malformation in cobblestone lissencephaly. In wild-type mice, dystroglycan stabilizes the basement membrane of the glia limitans, thereby supporting the cortical infrastructure necessary for neuronal migration. This function depends on extracellular dystroglycan interactions, since the cerebral cortex developed normally in transgenic mice that lack the dystroglycan intracellular domain. Also, forebrain histogenesis was preserved in mice with neuron-specific deletion of dystroglycan, but hippocampal long-term potentiation was blunted, as is also the case in the Largemyd mouse, in which dystroglycan glycosylation is disrupted. Our findings provide genetic evidence that neuronal dystroglycan plays a role in synaptic plasticity and that glial dystroglycan is involved in forebrain development. Differences in dystroglycan glycosylation in distinct cell types of the CNS may contribute to the diversity of dystroglycan function in the CNS, as well as to the broad clinical spectrum of type II lissencephalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980614"}
{"pmid": "20980617", "title": "Zds2p regulates Swe1p-dependent polarized cell growth in Saccharomyces cerevisiae via a novel Cdc55p interaction domain.", "content": "Zds2p regulates Swe1p-dependent polarized cell growth in Saccharomyces cerevisiae via a novel Cdc55p interaction domain. Deletion of the paralogs ZDS1 and ZDS2 in the budding yeast Saccharomyces cerevisiae causes a mis-regulation of polarized cell growth. Here we show a function for these genes as regulators of the Swe1p (Wee1p) kinase-dependent G2/M checkpoint. We identified a conserved domain in the C-terminus of Zds2p consisting of amino acids 813-912 (hereafter referred to as ZH4 for Zds homology 4) that is required for regulation of Swe1p-dependent polarized bud growth. ZH4 is shown by protein affinity assays to be necessary and sufficient for interaction with Cdc55p, a regulatory subunit of protein phosphatase 2A (PP2A). We hypothesized that the Zds proteins are in a pathway that negatively regulates the Swe1p-dependent G2/M checkpoint via Cdc55p. Supporting this model, deletion of CDC55 rescues the aberrant bud morphology of a zds1Δzds2Δ strain. We also show that expression of ZDS1 or ZDS2 from a strong galactose-inducible promoter can induce mitosis even when the Swe1p-dependent G2/M checkpoint is activated by mis-organization of the actin cytoskeleton. This negative regulation requires the CDC55 gene. Together these data indicate that the Cdc55p/Zds2p module has a function in the regulation of the Swe1p-dependent G2/M checkpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980617"}
{"pmid": "20980618", "title": "Compartment-restricted biotinylation reveals novel features of prion protein metabolism in vivo.", "content": "Compartment-restricted biotinylation reveals novel features of prion protein metabolism in vivo. Proteins are often made in more than one form, with alternate versions sometimes residing in different cellular compartments than the primary species. The mammalian prion protein (PrP), a cell surface GPI-anchored protein, is a particularly noteworthy example for which minor cytosolic and transmembrane forms have been implicated in disease pathogenesis. To study these minor species, we used a selective labeling strategy in which spatially restricted expression of a biotinylating enzyme was combined with asymmetric engineering of the cognate acceptor sequence into PrP. Using this method, we could show that even wild-type PrP generates small amounts of the (Ctm)PrP transmembrane form. Selective detection of (Ctm)PrP allowed us to reveal its N-terminal processing, long half-life, residence in both intracellular and cell surface locations, and eventual degradation in the lysosome. Surprisingly, some human disease-causing mutants in PrP selectively stabilized (Ctm)PrP, revealing a previously unanticipated mechanism of (Ctm)PrP up-regulation that may contribute to disease. Thus, spatiotemporal tagging has uncovered novel aspects of normal and mutant PrP metabolism and should be readily applicable to the analysis of minor topologic isoforms of other proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980618"}
{"pmid": "20980620", "title": "Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic site.", "content": "Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic site. Polycystin (PC)1 and PC2 are membrane proteins implicated in autosomal dominant polycystic kidney disease. A physiologically relevant cleavage at PC1's G protein-coupled receptor proteolytic site (GPS) occurs early in the secretory pathway. Our results suggest that PC2 increases both PC1 GPS cleavage and PC1's appearance at the plasma membrane. Mutations that prevent PC1's GPS cleavage prevent its plasma membrane localization. PC2 is a member of the trp family of cation channels and is an important PC1 binding partner. The effect of PC2 on PC1 localization is independent of PC2 channel activity, as tested using channel-inhibiting PC2 mutations. PC1 and PC2 can interact through their C-terminal tails, but removing the C-terminal tail of either protein has no effect on PC1 surface localization in human embryonic kidney 293 cells. Experiments in polarized LLC-PK cells show that apical and ciliary PC1 localization requires PC2 and that this delivery is sensitive to PC2 truncation. In sum, our work shows that PC2 expression is required for the movement of PC1 to the plasma and ciliary membranes. In fibroblast cells this localization effect is independent of PC2's channel activity or PC1 binding ability but involves a stimulation of PC1's GPS cleavage before the PC1 protein's surface delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980620"}
{"pmid": "20980619", "title": "Finding the cell center by a balance of dynein and myosin pulling and microtubule pushing: a computational study.", "content": "Finding the cell center by a balance of dynein and myosin pulling and microtubule pushing: a computational study. The centrosome position in many types of interphase cells is actively maintained in the cell center. Our previous work indicated that the centrosome is kept at the center by pulling force generated by dynein and actin flow produced by myosin contraction and that an unidentified factor that depends on microtubule dynamics destabilizes position of the centrosome. Here, we use modeling to simulate the centrosome positioning based on the idea that the balance of three forces-dyneins pulling along microtubule length, myosin-powered centripetal drag, and microtubules pushing on organelles-is responsible for the centrosome displacement. By comparing numerical predictions with centrosome behavior in wild-type and perturbed interphase cells, we rule out several plausible hypotheses about the nature of the microtubule-based force. We conclude that strong dynein- and weaker myosin-generated forces pull the microtubules inward competing with microtubule plus-ends pushing the microtubule aster outward and that the balance of these forces positions the centrosome at the cell center. The model also predicts that kinesin action could be another outward-pushing force. Simulations demonstrate that the force-balance centering mechanism is robust yet versatile. We use the experimental observations to reverse engineer the characteristic forces and centrosome mobility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980619"}
{"pmid": "20980621", "title": "A novel testis-specific GTPase serves as a link to proteasome biogenesis: functional characterization of RhoS/RSA-14-44 in spermatogenesis.", "content": "A novel testis-specific GTPase serves as a link to proteasome biogenesis: functional characterization of RhoS/RSA-14-44 in spermatogenesis. Most Rho family GTPases serve as key molecular switches in a wide spectrum of biological processes. An increasing number of studies have expanded their roles to the spermatogenesis. Several members of Rho family have been confirmed to be essential for mammalian spermatogenesis, but the precise roles of this family in male reproduction have not been well studied yet. Here we report a surprising function of an atypical and testis-specific Rho GTPase, RSA-14-44 in spermatogenesis. Featured by unique structural and expressional patterns, RSA-14-44 is distinguished from three canonical members of Rho cluster. Thus, we define RSA-14-44 as a new member of Rho GTPases family and rename it RhoS (Rho in spermatogenic cells). RhoS associates with PSMB5, a catalytic subunit of the proteasome, in a series of stage-specific spermatogenic cells. More importantly, RhoS does not directly modulate the cellular proteasome activity, but participates in regulating the stability of \"unincorporated\" PSMB5 precursors. Meanwhile, our data demonstrate that the activation of RhoS is prerequisite for negatively regulating the stability of PSMB5 precursors. Therefore, our finding uncovers a direct and functional connection between the Rho GTPase family and the pathway of proteasome biogenesis and provide new clues for deciphering the secrets of spermatogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980621"}
{"pmid": "20980622", "title": "Mps1 phosphorylation sites regulate the function of centrin 2 in centriole assembly.", "content": "Mps1 phosphorylation sites regulate the function of centrin 2 in centriole assembly. The nondegradable Mps1(Δ12/13) protein drives centriole overproduction, suggesting that Mps1 phosphorylates a subset of centrosomal proteins to drive the assembly of new centrioles. Here we identify three Mps1 phosphorylation sites within the centriolar protein Centrin 2 (Cetn2). Although centrioles can be assembled in the absence of Cetn2, centriole assembly is attenuated in the absence of Cetn2. While wild-type Cetn2 can compensate for this attenuation, a nonphosphorylatable version cannot. In addition, overexpressing Cetn2 causes Mps1-dependent centriole overproduction that requires each of the three Mps1 phosphorylation sites within Cetn2 and is greatly exacerbated by mimicking phosphorylation at any of these sites. Wild-type Cetn2 generates excess foci that are competent as mitotic spindle poles in HsSas-6-depleted cells, suggesting that Cetn2 can organize a subset of centriolar proteins independently of cartwheels. However, centriole overproduction caused by a phosphomimetic Cetn2 mutant requires HsSas-6, suggesting that Cetn2 phosphorylation stimulates the canonical centriole assembly pathway. Moreover, in the absence of Cetn2, Mps1(Δ12/13) cannot drive the production of mature centrioles capable of recruiting γ-Tubulin, and a nonphosphorylatable Cetn2 mutant cannot compensate for this defect and exacerbates Cetn2 depletion. Together, our data suggest that Mps1-dependent phosphorylation of Cetn2 stimulates the canonical centriole assembly pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980622"}
{"pmid": "20980624", "title": "Glut4 is upregulated despite decreased insulin signaling during prolonged fasting in northern elephant seal pups.", "content": "Glut4 is upregulated despite decreased insulin signaling during prolonged fasting in northern elephant seal pups. Postprandial cellular glucose uptake is dependent on an insulin-signaling cascade in muscle and adipose tissue, resulting in the translocation of the insulin-dependent glucose transporter 4 (Glut4) into the plasma membrane. Additionally, extended food deprivation is characterized by suppressed insulin signaling and decreased Glut4 expression. Northern elephant seals are adapted to prolonged fasts characterized by high levels of plasma glucose. To address the hypothesis that the fasting-induced decrease in insulin is associated with reduced insulin signaling in prolonged fasted seals, we compared the adipose protein levels of the cellular insulin-signaling pathway, Glut4 and plasma glucose, insulin, cortisol, and adiponectin concentrations between Early (n = 9; 2-3 wks postweaning) and Late (n = 8; 6-8 wks postweaning) fasted seals. Plasma adiponectin (230 ± 13 vs. 177 ± 11 ng/ml), insulin (2.7 ± 0.4 vs. 1.0 ± 0.1 μU/ml), and glucose (9.8 ± 0.5 vs. 8.0 ± 0.3 mM) decreased, while cortisol (124 ± 6 vs. 257 ± 30 nM) doubled with fasting. Glut4 increased (31%) with fasting despite the significant decreases in the cellular content of phosphatidylinositol 3-kinase as well as phosphorylated insulin receptor, insulin receptor substrate-1, and Akt2. Increased Glut4 may have contributed to the decrease in plasma glucose, but the decrease in insulin and insulin signaling suggests that Glut4 is not insulin-dependent in adipose tissue during prolonged fasting in elephant seals. The reduction of plasma glucose independent of insulin may make these animals an ideal model for the study of insulin resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980624"}
{"pmid": "20980625", "title": "Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit.", "content": "Sodium/glucose cotransporter-1, sweet receptor, and disaccharidase expression in the intestine of the domestic dog and cat: two species of different dietary habit. The domestic cat (Felis catus), a carnivore, naturally eats a very low carbohydrate diet. In contrast, the dog (Canis familiaris), a carno-omnivore, has a varied diet. This study was performed to determine the expression of the intestinal brush border membrane sodium/glucose cotransporter, SGLT1, sweet receptor, T1R2/T1R3, and disaccharidases in these species adapted to contrasting diets. The expression (this includes function) of SGLT1, sucrase, maltase and lactase were determined using purified brush border membrane vesicles and by quantitative immunohistochemistry of fixed tissues. The pattern of expression of subunits of the sweet receptor T1R2 and T1R3 was assessed using fluorescent immunohistochemistry. In proximal, middle, and distal small intestine, SGLT1 function in dogs was 1.9- to 2.3-fold higher than in cats (P = 0.037, P = 0.0011, P = 0.027, respectively), and SGLT1 protein abundance followed an identical pattern. Both cats and dogs express T1R3 in a subset of intestinal epithelial cells, and dogs, but not cats, express T1R2. In proximal and middle regions, there were 3.1- and 1.6-fold higher lactase (P = 0.006 and P = 0.019), 4.4- and 2.9-fold higher sucrase (both P < 0.0001), and 4.6- and 3.1-fold higher maltase activity (P = 0.0026 and P = 0.0005), respectively, in the intestine of dogs compared with cats. Dogs have a potential higher capacity to digest and absorb carbohydrates than cats. Cats may suffer from carbohydrate malabsorption following ingestion of high-carbohydrate meals. However, dogs have a digestive ability to cope with diets containing significant levels of carbohydrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980625"}
{"pmid": "20980626", "title": "CD8+ T cell responses against TAP-inhibited cells are readily detected in the human population.", "content": "CD8+ T cell responses against TAP-inhibited cells are readily detected in the human population. Target cell recognition by CTLs depends on the presentation of peptides by HLA class I molecules. Tumors and herpes viruses have adopted strategies to greatly hamper this peptide presentation at the important bottleneck, the peptide transporter TAP. Previously, we described the existence of a CD8(+) CTL subpopulation that selectively recognizes such TAP-deficient cells in mouse models. In this study, we show that the human counterpart of this CTL subset is readily detectable in healthy subjects. Autologous PBMC cultures were initiated with dendritic cells rendered TAP-impaired by gene transfer of the viral evasion molecule UL49.5. Strikingly, specific reactivity to B-LCLs expressing one of the other viral TAP-inhibitors (US6, ICP47, or BNLF2a) was already observed after three rounds of stimulation. These short-term T cell cultures and isolated CD8(+) CTL clones derived thereof did not recognize the normal B-LCL, indicating that the cognate peptide-epitopes emerge at the cell surface upon an inhibition in the MHC class I processing pathway. A diverse set of TCRs was used by the clones, and the cellular reactivity was TCR-dependent and HLA class I-restricted, implying the involvement of a broad antigenic peptide repertoire. Our data indicate that the human CD8(+) T cell pool comprises a diverse reactivity to target cells with impairments in the intracellular processing pathway, and these might be exploited for cancers that are associated with such defects and for infections with immune-evading herpes viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980626"}
{"pmid": "20980623", "title": "A novel role of Dma1 in regulating forespore membrane assembly and sporulation in fission yeast.", "content": "A novel role of Dma1 in regulating forespore membrane assembly and sporulation in fission yeast. In fission yeast Schizosaccharomyces pombe, a diploid mother cell differentiates into an ascus containing four haploid ascospores following meiotic nuclear divisions, through a process called sporulation. Several meiosis-specific proteins of fission yeast have been identified to play essential roles in meiotic progression and sporulation. We report here an unexpected function of mitotic spindle checkpoint protein Dma1 in proper spore formation. Consistent with its function in sporulation, expression of dma1(+) is up-regulated during meiosis I and II. We showed that Dma1 localizes to the SPB during meiosis and the maintenance of this localization at meiosis II depends on septation initiation network (SIN) scaffold proteins Sid4 and Cdc11. Cells lacking Dma1 display defects associated with sporulation but not nuclear division, leading frequently to formation of asci with fewer spores. Our genetic analyses support the notion that Dma1 functions in parallel with the meiosis-specific Sid2-related protein kinase Slk1/Mug27 and the SIN signaling during sporulation, possibly through regulating proper forespore membrane assembly. Our studies therefore revealed a novel function of Dma1 in regulating sporulation in fission yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980623"}
{"pmid": "20980628", "title": "Umbilical cord-derived mesenchymal stromal cells modulate monocyte function to suppress T cell proliferation.", "content": "Umbilical cord-derived mesenchymal stromal cells modulate monocyte function to suppress T cell proliferation. Mesenchymal stromal cells (MSCs) may be derived from a variety of tissues, with human umbilical cord (UC) providing an abundant and noninvasive source. Human UC-MSCs share similar in vitro immunosuppressive properties as MSCs obtained from bone marrow and cord blood. However, the mechanisms and cellular interactions used by MSCs to control immune responses remain to be fully elucidated. In this paper, we report that suppression of mitogen-induced T cell proliferation by human UC-, bone marrow-, and cord blood-MSCs required monocytes. Removal of monocytes but not B cells from human adult PBMCs (PBMNCs) reduced the immunosuppressive effects of MSCs on T cell proliferation. There was rapid modulation of a number of cell surface molecules on monocytes when PBMCs or alloantigen-activated PBMNCs were cultured with UC-MSCs. Indomethacin treatment significantly inhibited the ability of UC-MSCs to suppress T cell proliferation, indicating an important role for PGE(2). Monocytes purified from UC-MSC coculture had significantly reduced accessory cell and allostimulatory function when tested in subsequent T cell proliferation assays, an effect mediated in part by UC-MSC PGE(2) production and enhanced by PBMNC alloactivation. Therefore, we identify monocytes as an essential intermediary through which UC-MSCs mediate their suppressive effects on T cell proliferation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980628"}
{"pmid": "20980627", "title": "Elevated levels of soluble TNF receptors 1 and 2 correlate with Plasmodium falciparum parasitemia in pregnant women: potential markers for malaria-associated inflammation.", "content": "Elevated levels of soluble TNF receptors 1 and 2 correlate with Plasmodium falciparum parasitemia in pregnant women: potential markers for malaria-associated inflammation. Plasmodium falciparum-infected erythrocytes (IEs) sequester in the intervillous space (IVS) of the placenta causing placental malaria (PM), a condition that increases a woman's chances of having a low-birth-weight baby. Because IEs sequester, they frequently are not observed in peripheral blood smears, resulting in women with PM being misdiagnosed and thus not treated. Because sequestered IEs induce inflammation in the IVS, detection of inflammatory mediators in the peripheral blood may provide an approach for diagnosing PM. Two counterregulatory molecules, TNF-αR (TNFR) 1 and TNFR2, modulate the pathological effects of TNF-α. Levels of these soluble TNFRs (sTNFRs) are reported to be elevated in children with severe malaria, but it is unclear if they are increased in the peripheral blood of PM-positive women with asymptomatic infections. In this study, sTNFR levels were measured throughout the course of pregnancy, as well as at delivery, in women with asymptomatic infections and those who remained uninfected. Results showed that both sTNFRs were significantly increased in the peripheral blood of women with asymptomatic malaria (p < 0.0001) and were positively correlated with parasitemia (p < 0.0001 for sTNFR1 and p = 0.0046 for sTNFR2). Importantly, levels of sTNFR2 were elevated in the peripheral blood of women who were PM-positive but peripheral blood-smear negative (p = 0.0017). Additionally, sTNFR2 levels were elevated in the blood of malaria-positive women who delivered low-birth-weight babies. In vitro studies demonstrated that syncytiotrophoblasts were not a major source of sTNFR. These data suggest that sTNFR2 may be a valuable biomarker for detection of malaria-associated inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980627"}
{"pmid": "20980629", "title": "T cell polarity at the immunological synapse is required for CD154-dependent IL-12 secretion by dendritic cells.", "content": "T cell polarity at the immunological synapse is required for CD154-dependent IL-12 secretion by dendritic cells. Ag-specific interaction between T lymphocytes and dendritic cells (DCs) leads to both T cell and DC activation. CD154 (CD40 ligand)/CD40 interactions have been shown to play a major, although not exclusive, role in this functional cross-talk. Interactions between T cells and DCs are structured by an immunological synapse (IS), characterized by polarization of the T cell microtubule cytoskeleton toward the interacting DCs. Yet the role T cell polarization may play in T cell-induced DC activation is mostly unknown. In this study, we address the role of T cell polarity in CD154-dependent activation of DCs in a human model, using two different tools to block T cell polarity (i.e., a microtubule depolymerizing drug and an inhibitor of atypical protein kinase C). We show that CD154 is recruited and concentrated at the IS formed between human primary T cells and autologous DCs and that this recruitment requires T cell polarity at the IS. Moreover, we show that T cell polarization at the IS controls T cell-dependent CD154-CD40 signaling in DCs as well as CD154-dependent IL-12 secretion by DCs. This study shows that T cell polarity at the IS plays a key role in CD154/CD40-dependent cross-talk between CD4(+) T cells and DCs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980629"}
{"pmid": "20980630", "title": "CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response.", "content": "CCR2 identifies a stable population of human effector memory CD4+ T cells equipped for rapid recall response. Because T cells act primarily through short-distance interactions, homing receptors can identify colocalizing cells that serve common functions. Expression patterns for multiple chemokine receptors on CD4(+) T cells from human blood suggested a hierarchy of receptors that are induced and accumulate during effector/memory cell differentiation. We characterized CD4(+)CD45RO(+) T cells based on expression of two of these receptors, CCR5 and CCR2, the principal subsets being CCR5(-)CCR2(-) (∼70%), CCR5(+)CCR2(-) (∼25%), and CCR5(+)CCR2(+) (∼5%). Relationships among expression of CCR5 and CCR2 and CD62L, and the subsets' proliferation histories, suggested a pathway of progressive effector/memory differentiation from the CCR5(-)CCR2(-) to CCR5(+)CCR2(-) to CCR5(+)CCR2(+) cells. Sensitivity and rapidity of TCR-mediated activation, TCR signaling, and effector cytokine production by the subsets were consistent with such a pathway. The subsets also showed increasing responsiveness to IL-7, and the CCR5(+)CCR2(+) cells were CD127(bright) and invariably showed the greatest response to tetanus toxoid. CCR5(+)CCR2(+) cells also expressed the largest repertoire of chemokine receptors and migrated to the greatest number of chemokines. By contrast, the CCR5(+)CCR2(-) cells had the greatest percentages of regulatory T cells, activated/cycling cells, and CMV-reactive cells, and were most susceptible to apoptosis. Our results indicate that increasing memory cell differentiation can be uncoupled from susceptibility to death, and is associated with an increase in chemokine responsiveness, suggesting that vaccination (or infection) can produce a stable population of effector-capable memory cells that are highly enriched in the CCR5(+)CCR2(+) subset and ideally equipped for rapid recall responses in tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980630"}
{"pmid": "20980631", "title": "EBV latent membrane protein 1 is a negative regulator of TLR9.", "content": "EBV latent membrane protein 1 is a negative regulator of TLR9. EBV infects most of the human population and is associated with a number of human diseases including cancers. Moreover, evasion of the immune system and chronic infection is an essential step for EBV-associated diseases. In this paper, we show that EBV can alter the regulation and expression of TLRs, the key effector molecules of the innate immune response. EBV infection of human primary B cells resulted in the inhibition of TLR9 functionality. Stimulation of TLR9 on primary B cells led to the production of IL-6, TNF-α, and IgG, which was inhibited in cells infected with EBV. The virus exerts its inhibitory function by decreasing TLR9 mRNA and protein levels. This event was observed at early time points after EBV infection of primary cells, as well as in an immortalized lymphoblastoid cell line. We determined that the EBV oncoprotein latent membrane protein 1 (LMP1) is a strong inhibitor of TLR9 transcription. Overexpression of LMP1 in B cells reduced TLR9 promoter activity, mRNA, and protein levels. LMP1 mutants altered in activating the NF-κB pathway prevented TLR9 promoter deregulation. Blocking the NF-κB pathway recovered TLR9 promoter activity. Mutating the NF-κB cis element on the TLR9 promoter restored luciferase transcription in the presence of LMP1. Finally, deletion of the LMP1 gene in the EBV genome abolished the ability of the virus to induce TLR9 downregulation. Our study describes a mechanism used by EBV to suppress the host immune response by deregulating the TLR9 transcript through LMP1-mediated NF-κB activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980631"}
{"pmid": "20980633", "title": "Lymphocyte development requires S-nitrosoglutathione reductase.", "content": "Lymphocyte development requires S-nitrosoglutathione reductase. NO is critical to immunity, but its role in the development of the immune system is unknown. In this study, we show that S-nitrosoglutathione reductase (GSNOR), a protein key to the control of protein S-nitrosylation, is important for the development of lymphocytes. Genetic deletion of GSNOR in mice results in significant decrease in both T and B lymphocytes in the periphery. In thymus, GSNOR deficiency causes excessive protein S-nitrosylation, increases apoptosis, and reduces the number of CD4 single-positive thymocytes. Lymphopenia and increase in S-nitrosylation and apoptosis in GSNOR-deficient mice are largely abolished by genetic deletion of inducible NO synthase. Furthermore, the protection of lymphocyte development by GSNOR is apparently intrinsic to hematopoietic cells. Thus, GSNOR, likely through regulation of S-nitrosylation and apoptosis, physiologically plays a protective role in the development of the immune system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980633"}
{"pmid": "20980632", "title": "TLR-activated dendritic cells enhance the response of aged naive CD4 T cells via an IL-6-dependent mechanism.", "content": "TLR-activated dendritic cells enhance the response of aged naive CD4 T cells via an IL-6-dependent mechanism. The most effective immunological adjuvants contain microbial products, such as TLR agonists, which bind to conserved pathogen recognition receptors. These activate dendritic cells (DCs) to become highly effective APCs. We assessed whether TLR ligand-treated DCs can enhance the otherwise defective response of aged naive CD4 T cells. In vivo administration of CpG, polyinosinic-polycytidylic acid, and Pam(3)CSK(4) in combination with Ag resulted in the increased expression of costimulatory molecules and MHC class II by DCs, increased serum levels of the inflammatory cytokines IL-6 and RANTES, and increased cognate CD4 T cell responses in young and aged mice. We show that, in vitro, preactivation of DCs by TLR ligands makes them more efficient APCs for aged naive CD4 T cells. After T-DC interaction, there are enhanced production of inflammatory cytokines, particularly IL-6, and greater expansion of the aged T cells, resulting from increased proliferation and greater effector survival with increased levels of Bcl-2. TLR preactivation of both bone marrow-derived and ex vivo DCs improved responses. IL-6 produced by the activated DCs during cognate T cell interaction was necessary for enhanced aged CD4 T cell expansion and survival. These studies suggest that some age-associated immune defects may be overcome by targeted activation of APCs by TLR ligands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980632"}
{"pmid": "20980634", "title": "Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway.", "content": "Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway. Galectin-3, a β-galactoside-binding lectin, has been proposed to have multifaceted functions in various pathophysiological conditions. However, the characteristics of galectin-3 and its molecular mechanisms of action are still largely unknown. In this study, we show that galectin-3 exerts cytokine-like regulatory actions in rat and mouse brain-resident immune cells. Both the expression of galectin-3 and its secretion into the extracellular compartment were significantly enhanced in glia under IFN-γ-stimulated, inflamed conditions. After exposure to galectin-3, glial cells produced high levels of proinflammatory mediators and exhibited activated properties. Notably, within minutes after exposure to galectin-3, JAK2 and STAT1, STAT3, and STAT5 showed considerable enhancement of tyrosine phosphorylation; thereafter, downstream events of STAT signaling were also significantly enhanced. Treatment of the cells with pharmacological inhibitors of JAK2 reduced the galectin-3-stimulated increases of inflammatory mediators. Using IFN-γ receptor 1-deficient mice, we further found that IFN-γR 1 might be required for galectin-3-dependent activation of the JAK-STAT cascade. However, galectin-3 significantly induced phosphorylation of STATs in glial cells from IFN-γ-deficient mice, suggesting that IFN-γ does not mediate activation of STATs. Collectively, our findings suggest that galectin-3 acts as an endogenous danger signaling molecule under pathological conditions in the brain, providing a potential explanation for the molecular basis of galectin-3-associated pathological events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980634"}
{"pmid": "20980636", "title": "Lactobacillus plantarum consumption increases PepT1-mediated amino acid absorption by enhancing protein kinase C activity in spontaneously colitic mice.", "content": "Lactobacillus plantarum consumption increases PepT1-mediated amino acid absorption by enhancing protein kinase C activity in spontaneously colitic mice. Although probiotic consumption has generally been shown to have many beneficial effects for the prevention and treatment of inflammatory bowel disease, the effects of Lactobacillus plantarum (LP) on intestinal nutrient absorption, particularly oligopeptide transporter 1 (PepT1)-mediated absorption of dietary protein under inflammatory conditions, has not yet been characterized. In this study, we first investigated the effects of LP consumption on plasma amino acid concentrations and PepT1-mediated absorption of cephalexin in the small intestine of wild-type (WT) mice and interleukin-10 knockout (IL-10(-/-)) mice, a model of spontaneous colitis. We then analyzed expression and distribution of PepT1 and protein kinase C (PKC) activity in the jejunum of these mice. LP consumption (10(9) colony-forming units/0.5 mL) delivered by gavage once per day for 4 wk increased the total plasma amino acid concentration and the concentration of plasma cephalexin through enhancement of PepT1-mediated uptake in LP treated IL-10(-/-) mice compared with IL-10(-/-) mice. However, Western blotting and quantitative PCR analysis revealed no significant differences in PepT1 protein and mRNA expression between LP-treated and untreated mice. Additionally, immunofluorescence analysis showed that PepT1 did not appear to be mislocalized in IL-10(-/-) mice. Interestingly, IL-10(-/-) mice had significantly lower PKC activity and expression of phosphorylated PKC compared with WT mice, and these decreases could be prevented by LP treatment. These data suggest that consumption of LP enhances PepT1-mediated amino acid absorption, likely through alterations in PKC activity, as opposed to changes in expression or distribution of PepT1 in the small intestine of IL-10(-/-) mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980636"}
{"pmid": "20980635", "title": "Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism.", "content": "Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism. Recognition of drugs by immune cells is usually explained by the hapten model, which states that endogenous metabolites bind irreversibly to protein to stimulate immune cells. Synthetic metabolites interact directly with protein-generating antigenic determinants for T cells; however, experimental evidence relating intracellular metabolism in immune cells and the generation of physiologically relevant Ags to functional immune responses is lacking. The aim of this study was to develop an integrated approach using animal and human experimental systems to characterize sulfamethoxazole (SMX) metabolism-derived antigenic protein adduct formation in immune cells and define the relationship among adduct formation, cell death, costimulatory signaling, and stimulation of a T cell response. Formation of SMX-derived adducts in APCs was dose and time dependent, detectable at nontoxic concentrations, and dependent on drug-metabolizing enzyme activity. Adduct formation above a threshold induced necrotic cell death, dendritic cell costimulatory molecule expression, and cytokine secretion. APCs cultured with SMX for 16 h, the time needed for drug metabolism, stimulated T cells from sensitized mice and lymphocytes and T cell clones from allergic patients. Enzyme inhibition decreased SMX-derived protein adduct formation and the T cell response. Dendritic cells cultured with SMX and adoptively transferred to recipient mice initiated an immune response; however, T cells were stimulated with adducts derived from SMX metabolism in APCs, not the parent drug. This study shows that APCs metabolize SMX; subsequent protein binding generates a functional T cell Ag. Adduct formation above a threshold stimulates cell death, which provides a maturation signal for dendritic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980635"}
{"pmid": "20980639", "title": "Insights gained from 20 years of soy research.", "content": "Insights gained from 20 years of soy research. Soyfoods have long been recognized for their high-protein and low-saturated fat content, but over the past 20 y an impressive amount of soy-related research has evaluated the role of these foods in reducing chronic disease risk. Much of this research has been undertaken because the soybean is essentially a unique dietary source of isoflavones, a group of chemicals classified as phytoestrogens. The estrogen-like properties of isoflavones have also raised concern, however, that soyfoods might exert adverse effects in some individuals. There is intriguing animal and epidemiologic evidence indicating that modest amounts of soy consumed during childhood and/or adolescence reduces breast cancer risk. Evidence also suggests that soy reduces prostate cancer risk and inhibits prostate tumor metastasis, but additional clinical support for the chemopreventive effects of soyfoods is needed. Soy protein is modestly hypocholesterolemic and there is suggestive epidemiologic evidence that soyfoods lower risk of coronary heart disease (CHD) independent of effects on cholesterol. In clinical studies, soy favorably affects multiple CHD risk factors; however, with the exception of improved endothelial function, the data are too limited and/or inconsistent to allow definitive conclusions to be made. In regard to bone health, although recent clinical data have not supported the skeletal benefits of isoflavones, 2 large prospective epidemiologic studies found soy intake is associated with marked reductions in fracture risk. Soybean isoflavones also modestly alleviate hot flashes in menopausal women. Finally, other than allergic reactions, there is almost no credible evidence to suggest traditional soyfoods exert clinically relevant adverse effects in healthy individuals when consumed in amounts consistent with Asian intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980639"}
{"pmid": "20980637", "title": "Chronic parenteral nutrition induces hepatic inflammation, steatosis, and insulin resistance in neonatal pigs.", "content": "Chronic parenteral nutrition induces hepatic inflammation, steatosis, and insulin resistance in neonatal pigs. Prematurity and overfeeding in infants are associated with insulin resistance in childhood and may increase the risk of adult disease. Total parenteral nutrition (TPN) is a major source of infant nutritional support and may influence neonatal metabolic function. Our aim was to test the hypothesis that TPN induces increased adiposity and insulin resistance compared with enteral nutrition (EN) in neonatal pigs. Neonatal pigs were either fed enteral formula orally or i.v. administered a TPN mixture for 17 d; macronutrient intake was similar in both groups. During the 17-d period, we measured body composition by dual-energy X-ray absorptiometry scanning; fasting i.v. glucose tolerance tests (IVGTT) and hyperinsulinemic-euglycemic clamps (CLAMP) were performed to quantify insulin resistance. On d 17, tissue was collected after 1-h, low-dose CLAMP for tissue insulin signaling assays. TPN pigs gained less lean and more body fat and developed hepatic steatosis compared with EN pigs. After 7 and 13 d, IVGTT showed evidence of insulin resistance in the TPN compared with the EN group. Fasting plasma glucose and insulin also were higher in TPN pigs. CLAMP showed that insulin sensitivity was markedly lower in TPN pigs than in EN pigs. TPN also reduced the abundance of the insulin receptor, insulin receptor substrate 1, and phosphatidylinositol 3 kinase in skeletal muscle and liver and the proliferation of total pancreatic cells and β-cells. Hepatic proinflammatory genes as well as c-Jun-N-terminal kinase 1 phosphorylation, plasma interleukin 6, and tumor necrosis factor-α were all higher in TPN pigs than in EN pigs. The results demonstrate that chronic TPN induces a hepatic inflammatory response that is associated with significant insulin resistance, hepatic steatosis, and fat deposition compared with EN in neonatal pigs. Further studies are warranted to establish the mechanism of TPN-induced insulin resistance and hepatic metabolic dysfunction and whether there are persistent metabolic consequences of this lifesaving form of infant nutritional support.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980637"}
{"pmid": "20980640", "title": "Simulation with soy replacement showed that increased soy intake could contribute to improved nutrient intake profiles in the U.S. population.", "content": "Simulation with soy replacement showed that increased soy intake could contribute to improved nutrient intake profiles in the U.S. population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980640"}
{"pmid": "20980641", "title": "Supplemental dietary inulin of variable chain lengths alters intestinal bacterial populations in young pigs.", "content": "Supplemental dietary inulin of variable chain lengths alters intestinal bacterial populations in young pigs. Previously, we showed that supplementation of diets with short-chain inulin (P95), long-chain inulin (HP), and a 50:50 mixture of both (Synergy 1) improved body iron status and altered expression of the genes involved in iron homeostasis and inflammation in young pigs. However, the effects of these 3 types of inulin on intestinal bacteria remain unknown. Applying terminal restriction fragment length polymorphism analysis, we determined the abundances of luminal and adherent bacterial populations from 6 segments of the small and large intestines of pigs (n = 4 for each group) fed an iron-deficient basal diet (BD) or the BD supplemented with 4% of P95, Synergy 1, or HP for 5 wk. Compared with BD, all 3 types of inulin enhanced (P < 0.05) the abundance of beneficial bifidobacteria and lactobacilli in the microbiota adherent to intestinal mucus of various gut segments of pigs. These changes were seen as proximal as in the jejunum with P95 but did not appear until the distal ileum or cecum with HP. Similar effects of inulin on bacterial populations in the lumen contents were found. Meanwhile, all 3 types of inulin suppressed the less desirable bacteria Clostridium spp. and members of the Enterobacteriaceae in the lumen and mucosa of various gut segments. Our findings suggest that the ability of dietary inulin to alter intestinal bacterial populations may partially account for its iron bioavailability-promoting effect and possibly other health benefits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980641"}
{"pmid": "20980638", "title": "Is soy consumption good or bad for the breast?", "content": "Is soy consumption good or bad for the breast? Genistein in soy activates estrogen receptor (ER)-α and ERβ and acts as an estradiol in multiple target tissues. Because estrogens increase breast cancer risk and genistein promotes the growth of ER-positive human breast cancer cells, it has remained unclear whether this isoflavone or soy is safe. Results reviewed here suggest that women consuming moderate amounts of soy throughout their life have lower breast cancer risk than women who do not consume soy; however, this protective effect may originate from soy intake early in life. We also review the literature regarding potential risks genistein poses for breast cancer survivors. Findings obtained in 2 recent human studies show that a moderate consumption of diet containing this isoflavone does not increase the risk of breast cancer recurrence in Western women, and Asian breast cancer survivors exhibit better prognosis if they continue consuming a soy diet. The mechanisms explaining the breast cancer risk-reducing effect of early soy intake or the protective effect in Asian breast cancer survivors remain to be established. We propose that the reduction in risk involves epigenetic changes that result in alterations in the expression of genes that regulate mammary epithelial cell fate, i.e. cell proliferation and differentiation. Lifetime soy consumption at a moderate level may prevent breast cancer recurrence through mechanisms that change the biology of tumors; e.g. women who consumed soy during childhood develop breast cancers that express significantly reduced Human epidermal growth factor receptor 2 levels. More research is needed to understand why soy intake during early life may both reduce breast cancer risk and risk of recurrence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980638"}
{"pmid": "20980642", "title": "Adult ovarian function can be affected by high levels of soy.", "content": "Adult ovarian function can be affected by high levels of soy. Ovarian function in adults is controlled by hormones circulating in the body. The primary hormone responsible for cyclicity in animals and humans is estrogen. Estrogen is mostly produced in the ovary and enters the circulation where it then signals the brain for a response. The parts of the brain that controls reproductive hormones are the hypothalamus and anterior pituitary. Estrogen stimulates the hypothalamus to produce gonadotropin releasing hormone, which in turn signals the anterior pituitary to produce follicle stimulating hormone and luteinizing hormone. These hormones enter the circulation and signal the ovary to ovulate. Substances with estrogenic activity can potentially interfere with this signaling if levels of activity are sufficient to cause a response. Soy foods contain estrogenic substances called phytoestrogens. The predominant phytoestrogens found in soy are genistein and daidzein. The female reproductive system is dependent on hormones for proper function and phytoestrogens at very high levels can interfere with this process. This paper summarizes the literature on adult soy consumption and its effect on ovarian function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980642"}
{"pmid": "20980643", "title": "Red meat and a fortified manufactured toddler milk drink increase dietary zinc intakes without affecting zinc status of New Zealand toddlers.", "content": "Red meat and a fortified manufactured toddler milk drink increase dietary zinc intakes without affecting zinc status of New Zealand toddlers. Evidence suggests that New Zealand (NZ) children are mildly zinc deficient and may respond to dietary change. A 20-wk randomized intervention trial was therefore conducted to determine whether an increased intake of red meat or consumption of a fortified manufactured toddler milk drink (FTMD, fortified with zinc and other micronutrients) would increase dietary zinc intakes and improve the biochemical zinc status of 12- to 20-mo-old NZ toddlers. Toddlers were randomized to a red meat intervention (n = 90), FTMD intervention (n = 45), or nonfortified milk placebo (n = 90). Study foods were provided. Adherence was assessed via monthly 7-d meat or milk recording diaries. Hair and serum zinc concentrations, and length and weight were measured at baseline and postintervention. Nutrient intakes were assessed via 3-d weighed food records at baseline, wk 4, and wk 18. At baseline, 38% of participants had low serum zinc concentrations despite seemingly adequate dietary zinc intakes (<4% below the Estimated Average Requirement). Dietary zinc intakes significantly increased by 0.8 mg/d (95% CI: 0.5, 1.1) in the meat group and 0.7 mg/d (95% CI: 0.2, 1.1) in the FTMD group compared with a decrease of -0.5 (95% CI: -0.8, -0.2) mg/d in the placebo group. No corresponding increases in serum or hair zinc concentrations were observed. Dietary zinc intakes achievable via interventions based on red meat or a FTMD are unlikely to improve biochemical zinc status in NZ toddlers. These results also question cutoffs used to define zinc deficiency in toddlers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980643"}
{"pmid": "20980644", "title": "Ruminant-produced trans-fatty acids raise plasma total and small HDL particle concentrations in male Hartley guinea pigs.", "content": "Ruminant-produced trans-fatty acids raise plasma total and small HDL particle concentrations in male Hartley guinea pigs. Although trans-fatty acid (tFA) intake has been positively associated with coronary heart disease (CHD), the relative effect of consuming industrially produced (IP)- compared with ruminant-produced (RP)-tFA on CHD risk factors is unclear. This study was designed to examine the effects of feeding partially hydrogenated vegetable oil (PHVO), IP-tFA source, and butter oil (BO), RP-tFA source, on the development of atherosclerosis and risk factors associated with CHD. Forty-eight male Hartley guinea pigs were fed a hypercholesterolemic diet containing (9% by weight) PHVO, BO, coconut oil (CO; positive control), or soybean oil (SO; negative control) for 8 or 12 wk (n = 6/group). Morphological analysis revealed that none of the groups developed atherosclerosis. Plasma and hepatic lipids did not differ between the tFA groups, but total and small HDL particles were significantly higher in the BO group than in the PHVO group and mean HDL particle size was significantly smaller in the BO group than in the PHVO group. Compared with the other treatment groups, the SO treatment resulted in significantly lower total cholesterol (TC) and LDL cholesterol in plasma, whereas hepatic TC was significantly higher in the SO group than in the other treatment groups. Plasma and hepatic cholesterol concentrations did not differ between the tFA and CO treatments. These results demonstrate that when fed at a high dose, IP- and RP-tFA had the same effect on established CHD risk factors in male Hartley guinea pigs. The effects of RP-tFA on HDL particle sizes and concentrations warrant further investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980644"}
{"pmid": "20980646", "title": "Resveratrol protects against oxidized LDL-induced breakage of the blood-brain barrier by lessening disruption of tight junctions and apoptotic insults to mouse cerebrovascular endothelial cells.", "content": "Resveratrol protects against oxidized LDL-induced breakage of the blood-brain barrier by lessening disruption of tight junctions and apoptotic insults to mouse cerebrovascular endothelial cells. Cerebrovascular endothelial cells (CEC) comprise the blood-brain barrier (BBB). In a previous study, we showed that oxidized LDL (oxLDL) can induce apoptosis of mouse CEC. Resveratrol possesses chemopreventive potential. This study aimed to evaluate the effects of resveratrol on oxLDL-induced insults to mouse CEC and its possible mechanisms. Exposure of mouse CEC to 200 μmol/L oxLDL for 1 h did not cause cell death but significantly altered the permeability and transendothelial electrical resistance of the cell monolayer. However, resveratrol completely normalized such injury. As for the mechanisms, resveratrol completely protected oxLDL-induced disruption of F-actin and microtubule cytoskeletons as well as occludin and zona occludens-1 (ZO-1) tight junctions. The oxLDL-induced decreases in the mitochondrial membrane potential and intracellular ATP levels were normalized by resveratrol. Exposure of mouse CEC to 200 μmol/L oxLDL for 24 h elevated oxidative stress and simultaneously induced cell apoptosis. However, resveratrol partially protected against oxLDL-induced CEC apoptosis. The oxLDL-induced alterations in levels of Bcl-2, Bax, and cytochrome c were completely normalized by resveratrol. Consequently, resveratrol partially decreased oxLDL-induced activation of caspases-9 and -3. Therefore, in this study, we show that resveratrol can protect against oxLDL-induced damage of the BBB through protecting disruption of the tight junction structure and apoptotic insults to CEC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980646"}
{"pmid": "20980647", "title": "Soy components vs. whole soy: are we betting our bones on a long shot?", "content": "Soy components vs. whole soy: are we betting our bones on a long shot? Soybeans are a good source of bone-healthy nutrients. Epidemiological studies in Asia evaluating diets containing traditional whole soy foods show a positive association with bone mineral density and fracture protection. Smaller scale intervention studies in Western nations mainly feature isolated soy protein (SP) and purified or concentrated soy isoflavones (SI) rather than whole soy foods and they have produced inconsistent results. Consumption of SP does not alter calcium (Ca) retention even though urinary Ca excretion is less in diets with SP compared with proteins higher in sulfur-containing amino acids. SI, often consumed at higher concentrations than would be available in traditional Asian diets, are not yielding the type of incontrovertible evidence that might be expected in support of their benefit to bone health. This forces one to ask whether whole soy might provide a superior effect on bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980647"}
{"pmid": "20980648", "title": "A ready-to-use therapeutic food containing 10% milk is less effective than one with 25% milk in the treatment of severely malnourished children.", "content": "A ready-to-use therapeutic food containing 10% milk is less effective than one with 25% milk in the treatment of severely malnourished children. Standard therapy for severe acute malnutrition (SAM) is home-based therapy with ready-to-use therapeutic food (RUTF) containing 25% milk. In an effort to lower the cost of RUTF and increase availability, some have suggested that a portion of milk be replaced with soy. This trial was designed to determine whether treating children with SAM with 10% milk RUTF containing soy would result in a similar recovery rate compared with the 25% milk RUTF. This was a randomized, double-blind, controlled, clinical, quasi-effectiveness trial of isoenergetic amounts of 2 locally produced RUTF to treat SAM in Malawi among children aged 6-59 mo. A total of 1874 children were enrolled. Children were assessed every fortnight and participated in the study until they clinically recovered or received 8 wk of treatment. The primary outcome was recovery (weight-for-height Z score > -2 and no edema). Secondary outcomes were rates of weight and height gain. Survival analysis was used to compare the recovery rates. Recovery among children receiving 25% milk RUTF was greater than children receiving 10% milk RUTF, 64% compared with 57% after 4 wk, and 84% compared with 81% after 8 wk (P < 0.001). Children receiving 25% milk RUTF also had higher rates of weight and height gain compared with children receiving 10% milk RUTF. Treating children with SAM with 10% milk RUTF is less effective compared with treatment with the standard 25% milk RUTF. These findings also emphasize that clinical evidence should be examined before recommending any changes to the formulation of RUTF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980648"}
{"pmid": "20980645", "title": "Beta-carotene is an important vitamin A source for humans.", "content": "Beta-carotene is an important vitamin A source for humans. Experts in the field of carotenoids met at the Hohenheim consensus conference in July 2009 to elucidate the current status of β-carotene research and to summarize the current knowledge with respect to the chemical properties, physiological function, and intake of β-carotene. The experts discussed 17 questions and reached an agreement formulated in a consensus answer in each case. These consensus answers are based on published valid data, which were carefully reviewed by the individual experts and are justified here by background statements. Ascertaining the impact of β-carotene on the total dietary intake of vitamin A is complicated, because the efficiency of conversion of β-carotene to retinol is not a single ratio and different conversion factors have been used in various surveys and following governmental recommendations within different countries. However, a role of β-carotene in fulfilling the recommended intake for vitamin A is apparent from a variety of studies. Thus, besides elucidating the various functions, distribution, and uptake of β-carotene, the consensus conference placed special emphasis on the provitamin A function of β-carotene and the role of β-carotene in the realization of the required/recommended total vitamin A intake in both developed and developing countries. There was consensus that β-carotene is a safe source of vitamin A and that the provitamin A function of β-carotene contributes to vitamin A intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980645"}
{"pmid": "20980650", "title": "Rye whole grain and bran intake compared with refined wheat decreases urinary C-peptide, plasma insulin, and prostate specific antigen in men with prostate cancer.", "content": "Rye whole grain and bran intake compared with refined wheat decreases urinary C-peptide, plasma insulin, and prostate specific antigen in men with prostate cancer. Rye whole grain and bran intake has shown beneficial effects on prostate cancer progression in animal models, including lower tumor take rates, smaller tumor volumes, and reduced prostate specific antigen (PSA) concentrations. A human pilot study showed increased apoptosis after consumption of rye bran bread. In this study, we investigated the effect of high intake of rye whole grain and bran on prostate cancer progression as assessed by PSA concentration in men diagnosed with prostate cancer. Seventeen participants were provided with 485 g rye whole grain and bran products (RP) or refined wheat products with added cellulose (WP), corresponding to ~50% of daily energy intake, in a randomized controlled, crossover design. Blood samples were taken from fasting men before and after 2, 4, and 6 wk of treatment and 24-h urine samples were collected before the first intervention period and after treatment. Plasma total PSA concentrations were lower after treatment with RP compared with WP, with a mean treatment effect of -14% (P = 0.04). Additionally, fasting plasma insulin and 24-h urinary C-peptide excretion were lower after treatment with RP compared with WP (P < 0.01 and P = 0.01, respectively). Daily excretion of 5 lignans was higher after the RP treatment than after the WP treatment (P < 0.001). We conclude that whole grain and bran from rye resulted in significantly lower plasma PSA compared with a cellulose-supplemented refined wheat diet in patients with prostate cancer. The effect may be related to inhibition of prostate cancer progression caused by decreased exposure to insulin, as indicated by plasma insulin and urinary C-peptide excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980650"}
{"pmid": "20980649", "title": "A low-protein diet during gestation in rats activates the placental mammalian amino acid response pathway and programs the growth capacity of offspring.", "content": "A low-protein diet during gestation in rats activates the placental mammalian amino acid response pathway and programs the growth capacity of offspring. Placental efficiency is a predictor of fetal growth and development, which is also controlled by maternal gestational health and diet. The present study investigated the effects of a gestational low-protein diet on offspring growth capacity as well as the diet's contribution to altered expression of placental genes associated with the mammalian amino acid response (AAR) pathway. To assess these outcomes, timed-pregnant Sprague Dawley rats were fed a control (C) diet with 18% protein or a low-protein (LP) diet with 9% protein throughout gestation (Expt. 1) or throughout gestation and lactation (Expt. 2). Placentas were collected during natural delivery and quantitative RT-PCR and Western-blot analyses were performed to determine placental mRNA and protein levels. By the end of the lactation period, offspring of dams fed the LP diet had stunted growth in both experiments. mRNA expression of target genes in the AAR pathway, such as activating transcription factor-3 (Atf3), asparagine synthetase (Asns), and Sodium-dependent neutral amino acid transporter-2 (Snat2), was greater in placentas of rats fed the LP diet compared with controls, as were placental ATF4 and p-eIF2α protein levels. The increase in mRNA expression of AAR pathway-associated genes was correlated with the stunting of offspring growth (Atf3: R(2) = 0.32, P = 0.086; Asns: R(2) = 0.44, P < 0.05; Snat2: R(2) = 0.33, P = 0.084). Our study showed that the mammalian AAR pathway in placenta is upregulated by a maternal low-protein diet and this activation may act as a cue for the fetus to develop an adaptive response suited to their predicted postnatal environment, i.e. a more favorable phenotype for their survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980649"}
{"pmid": "20980652", "title": "Whole versus the piecemeal approach to evaluating soy.", "content": "Whole versus the piecemeal approach to evaluating soy. Soy has been singled out for attention among other legumes as a valuable source of nutrients, phytochemicals, and bioactive compounds. Early epidemiological studies established that whole soy and traditional soy foods were implicated in health-protective effects in Asian populations. The same benefits attributable to soy have not been consistently proven in Western populations that, for various reasons, opt to consume more processed soy foods or various soy components. Soy researchers continue to isolate soy components in search of identifying its salubrious components and whole soy remains relatively underinvestigated despite what we know of the health benefits it may confer to those regularly consuming it. Various dietary guidelines advocate the regular consumption of legumes that tend not to be included in our diets in sufficient quantities. This paper highlights the possibility that whole soy may have a more unique effect on health than a select soy component(s). It explores the rationale for focusing research on whole soy in an attempt to understand it better rather than trying to replicate the health benefits by targeting various soy components, which has been plagued by inconsistent results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980652"}
{"pmid": "20980653", "title": "How much human milk do infants consume? Data from 12 countries using a standardized stable isotope methodology.", "content": "How much human milk do infants consume? Data from 12 countries using a standardized stable isotope methodology. The WHO has developed new growth curves based on breast-fed infants. Recommendations for energy intake have been adopted based on measurements of total energy expenditure. Data on human milk (HM) intake are needed to estimate the energy intake from this food source. However, objective HM data from around the world have not been available, because these measurements are difficult to obtain. Stable isotope methods have been developed to provide objective measurements over a 14-d period. A pooled analysis of 1115 data points of HM intake, obtained using the dose to the mother deuterium oxide turnover method, was undertaken in infants aged 0-24 mo from 12 countries across 5 continents. A hierarchical model was needed to estimate mean HM intake and its variance within and between countries given the complexity of the data. The overall mean HM intake was 0.78 (95% CI = 0.72, 0.84) kg/d, and the age-specific estimates indicated that intake increased over the first 3-4 mo and remained above 0.80 kg/d until 6-7 mo. The variability of intake increased in late infancy. Boys consumed 0.05 kg/d more than girls (P < 0.01). HM intake was strongly, inversely associated with non-HM water intake [r = -0.448 (95% CI -0.511 to -0.385); P < 0.0001]. These objective isotope values of HM intake improve our understanding of the magnitude and variability of HM intake within and across populations and help to estimate nutrient intakes in breast-fed infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980653"}
{"pmid": "20980651", "title": "Serum 25-hydroxyvitamin D concentrations fluctuate seasonally in young adults of diverse ancestry living in Toronto.", "content": "Serum 25-hydroxyvitamin D concentrations fluctuate seasonally in young adults of diverse ancestry living in Toronto. Previous research indicates that circulating vitamin D levels are low in many otherwise healthy adults and that there is considerable seasonal variation in 25-hydroxyvitamin D [25(OH)D] concentrations at high latitudes. We examined seasonal variation in 25(OH)D levels in a sample of young adults of diverse ancestry living in the Greater Toronto Area. Three hundred and fifty-one (351) healthy young adults completed both a fall and winter visit during this study. The study was conducted over 2 y (y 1: fall 2007 to winter 2008 and y 2: fall 2008 to winter 2009). At both visits, each participant's serum 25(OH)D concentration was measured. Information was also obtained on skin pigmentation (measured via reflectometer), vitamin D intake, and extent of sun exposure. Overall, the serum 25(OH)D concentration was 54.4 ± 1.3 nmol/L in the fall and 38.4 ± 1.1 nmol/L in the winter. Concentrations differed among ancestral groups at both visits (P < 0.001), with South Asians and East Asians having substantially lower concentrations than Europeans. Skin pigmentation (r(2) = 0.14; P < 0.001), supplemental vitamin D intake (r(2) = 0.09; P < 0.001), sun exposure (r(2) = 0.04; P < 0.001), and study year (r(2) = 0.02; P = 0.017) were predictors of fall 25(OH)D concentrations. During the wintertime, serum 25(OH)D concentrations were associated with concentrations taken in the fall (r(2) = 0.45; P < 0.001), supplemental (r(2) = 0.15; P < 0.001) and dietary vitamin D intake (r(2) = 0.06; P < 0.001), and with study year (r(2) = 0.02; P = 0.009). Our study confirms that serum 25(OH)D concentrations undergo strong seasonal variation at high latitudes and are influenced by vitamin D intake, skin pigmentation, and sun exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980651"}
{"pmid": "20980654", "title": "Consumption of wheat aleurone-rich foods increases fasting plasma betaine and modestly decreases fasting homocysteine and LDL-cholesterol in adults.", "content": "Consumption of wheat aleurone-rich foods increases fasting plasma betaine and modestly decreases fasting homocysteine and LDL-cholesterol in adults. There is strong evidence that whole-grain foods protect against heart disease. Although underlying mechanisms and components are unclear, betaine, found at high levels in wheat aleurone, may play a role. We evaluated the effects of a diet high in wheat aleurone on plasma betaine and related measures. In a parallel, single-blinded intervention study, 79 healthy participants (aged 45-65 y, BMI ≥ 25 kg/m(2)) incorporated either aleurone-rich cereal products (27 g/d aleurone) or control products balanced for fiber and macronutrients into their habitual diets for 4 wk. Fasting blood samples were taken at baseline and postintervention (4 wk) from participants. Compared with the control, the aleurone products provided an additional 279 mg/d betaine and resulted in higher plasma betaine (P < 0.001; intervention effect size: 5.2 μmol/L) and lower plasma total homocysteine (tHcy) (P = 0.010; -0.7 μmol/L). Plasma dimethylglycine and methionine, which are products of betaine-mediated homocysteine remethylation, were also higher (P < 0.001; P = 0.027) relative to control. There were no significant effects on plasma choline or B vitamins (folate, riboflavin, and vitamin B-6). However, LDL cholesterol was lower than in the control group (P = 0.037). We conclude that incorporating aleurone-rich products into the habitual diet for 4 wk significantly increases plasma betaine concentrations and lowers tHcy, which is attributable to enhanced betaine-homocysteine methyltransferase-mediated remethylation of homocysteine. Although this supports a role for betaine in the protective effects of whole grains, concomitant decreases in LDL suggest more than one component or mechanism may be responsible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980654"}
{"pmid": "20980655", "title": "Preface to journal supplement \"Soy Summit: Exploration of the Nutrition and Health Effects of Whole Soy\".", "content": "Preface to journal supplement \"Soy Summit: Exploration of the Nutrition and Health Effects of Whole Soy\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980655"}
{"pmid": "20980656", "title": "Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research.", "content": "Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research. Food intake, physical activity (PA), and genetic makeup each affect health and each factor influences the impact of the other 2 factors. Nutrigenomics describes interactions between genes and environment. Knowledge about the interplay between environment and genetics would be improved if experimental designs included measures of nutrient intake and PA. Lack of familiarity about how to analyze environmental variables and ease of access to tools and measurement instruments are 2 deterrents to these combined studies. This article describes the state of the art for measuring food intake and PA to encourage researchers to make their tools better known and more available to workers in other fields. Information presented was discussed during a workshop on this topic sponsored by the USDA, NIH, and FDA in the spring of 2009.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980656"}
{"pmid": "20980657", "title": "Complementary foods fortified with micronutrients prevent iron deficiency and anemia in Vietnamese infants.", "content": "Complementary foods fortified with micronutrients prevent iron deficiency and anemia in Vietnamese infants. To investigate whether an intervention including micronutrient-fortified complementary foods can improve iron status, we conducted a randomized controlled trial in 5-mo-old Vietnamese infants (n = 246). Villages (n = 29) were randomly divided into those receiving instant flour (FF) or a food complement (FC) both fortified with micronutrients or nothing [control (C)]. FF and FC infants received daily for 6 mo at least 2 meals of fortified complementary foods. Micronutrient status was assessed by measurement of hemoglobin (Hb) and plasma ferritin (PF), transferrin receptor, zinc, and retinol. Final Hb (mean ± SD) was higher in the FF (112.5 ± 8.0 g/L) and FC (114.0 ± 7.0 g/L) groups compared with C (109.0 ± 8.0 g/L; P = 0.006). PF (geometric mean [95% CI]) was also higher in FF (19.8 μg/L [17.5-22.3]) and FC (20.8 μg/L [18.3-23.6]) compared with C (11.1 μg/L [9.8-12.5]; P < 0.0001). Anemia prevalence decreased more in the FC group (-43.6%) compared with C (-10.3%; P = 0.006). The change in prevalence of PF < 12 μg/L was different in the FF (-16.4%) and FC (-6.7%) groups compared with C (+30.4%; P < 0.01). Endpoint prevalence of iron deficiency (ID) and ID anemia (IDA) were lower in the FF (13.4 and 6.7%, respectively) and FC (15.2 and 3.8%) groups compared with C (57.5 and 37.5%) (P < 0.0001). Retinol and zinc concentrations did not differ among groups, but endpoint prevalence of zinc deficiency was lower in FF infants (36.1%) than in C infants (52.9%; P = 0.04). Micronutrient-fortified complementary foods significantly improved iron status and decreased the prevalence of anemia, ID, and IDA in Vietnamese infants and can be an important tool to reduce ID in infancy in developing countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980657"}
{"pmid": "20980658", "title": "Utilization of iron from an animal-based iron source is greater than that of ferrous sulfate in pregnant and nonpregnant women.", "content": "Utilization of iron from an animal-based iron source is greater than that of ferrous sulfate in pregnant and nonpregnant women. Heme iron absorption during pregnancy and the role of hepcidin in regulating dietary heme iron absorption remains largely unexplored. The objective of this research was to examine relative differences in heme (animal based) and nonheme (ferrous sulfate) iron utilization. This study was undertaken in 18 pregnant (ages 16-32 y; wk 32-35 of gestation) and 11 nonpregnant women (ages 18-27 y). Women were randomly assigned to receive both an animal-based heme meal (intrinsically labeled (58)Fe pork) and labeled ferrous sulfate ((57)Fe) fed on alternate days. Blood samples obtained 2 wk postdosing were used to assess iron status indicators and serum hepcidin and iron utilization based on RBC incorporation of iron isotopes. Heme iron utilization was significantly greater than nonheme iron utilization in the pregnant (47.7 ± 14.4 vs. 40.4 ± 13.2%) and nonpregnant women (50.1 ± 14.8 vs. 15.3 ± 9.7%). Among pregnant women, utilization of nonheme iron was associated with iron status, as assessed by the serum transferrin receptor concentration (P = 0.003; r(2) = 0.43). In contrast, heme iron utilization was not influenced by maternal iron status. In the group as a whole, women with undetectable serum hepcidin had greater nonheme iron utilization compared with women with detectable serum hepcidin (P = 0.02; n = 29); however, there were no significant differences in heme iron utilization. Our study suggests that iron utilization from an animal-based food provides a highly bioavailable source of dietary iron for pregnant and nonpregnant women that is not as sensitive to hepcidin concentrations or iron stores compared with ferrous sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980658"}
{"pmid": "20980659", "title": "A DXA-based mathematical model predicts midthigh muscle mass from magnetic resonance imaging in typically developing children but not in those with quadriplegic cerebral palsy.", "content": "A DXA-based mathematical model predicts midthigh muscle mass from magnetic resonance imaging in typically developing children but not in those with quadriplegic cerebral palsy. Valid methods for assessing regional muscle mass in children are needed. The aim of this study was to determine whether dual-energy X-ray absorptiometry (DXA) can accurately estimate midthigh muscle mass from MRI (muscle(MRI)) in typically developing children and children with quadriplegic cerebral palsy (CP). A mathematical model predicting muscle(MRI) from midthigh, fat-free soft tissue mass from DXA (FFST(DXA)) was developed using 48 typically developing children (6-13 y) and was validated using the leave-one-out method. The model was also tested in children with quadriplegic CP (n = 10). The model produced valid estimates of midthigh muscle mass (muscle(DXA)) in typically developing children, as indicated by a very strong relationship between muscle(DXA) and muscle(MRI) (r(2) = 0.95; SEE = 68 g; P < 0.001), no difference in muscle(DXA) and muscle(MRI) (P = 0.951), and visual examination using a Bland-Altman plot. Muscle(DXA) was very strongly related to muscle(MRI) in children with CP (r(2) = 0.96; SEE = 54 g; P < 0.001); however, muscle(DXA) overestimated muscle(MRI) by 15% (P = 0.006). The overestimation of muscle(MRI) by muscle(DXA) was strongly related to the lower ratio of muscle(MRI) to FFST(DXA) (muscle(MRI)/FFST(DXA)) in children with CP (r(2) = 0.75; P = 0.001). The findings suggest that the DXA-based mathematical model developed in the current study can accurately estimate midthigh muscle mass in typically developing children. However, a population-specific model that takes into account the lower muscle(MRI)/FFST(DXA) is needed to estimate midthigh muscle mass in children with quadriplegic CP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980659"}
{"pmid": "20980660", "title": "Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.", "content": "Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution. Protein biosynthesis, the translation of the genetic code into polypeptides, occurs on ribonucleoprotein particles called ribosomes. Although X-ray structures of bacterial ribosomes are available, high-resolution structures of eukaryotic 80S ribosomes are lacking. Using cryoelectron microscopy and single-particle reconstruction, we have determined the structure of a translating plant (Triticum aestivum) 80S ribosome at 5.5-Å resolution. This map, together with a 6.1-Å map of a Saccharomyces cerevisiae 80S ribosome, has enabled us to model ∼98% of the rRNA. Accurate assignment of the rRNA expansion segments (ES) and variable regions has revealed unique ES-ES and r-protein-ES interactions, providing insight into the structure and evolution of the eukaryotic ribosome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980660"}
{"pmid": "20980661", "title": "Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway.", "content": "Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway. Inositol phosphate (IP) kinases constitute an emerging class of cellular kinases linked to multiple cellular activities. Here, we report a previously uncharacterized cellular function in Hedgehog (Hh) signaling for the IP kinase designated inositol hexakisphosphate kinase-2 (IP6K2) that produces diphosphoryl inositol phosphates (PP-IPs). In zebrafish embryos, IP6K2 activity was required for normal development of craniofacial structures, somites, and neural crest cells. ip6k2 depletion in both zebrafish and mammalian cells also inhibited Hh target gene expression. Inhibiting IP(6) kinase activity using N(2)-(m-(trifluoromethy)lbenzyl) N(6)-(p-nitrobenzyl)purine (TNP) resulted in altered Hh signal transduction. In zebrafish, restoring IP6K2 levels with exogenous ip6k2 mRNA reversed the effects of IP6K2 depletion. Furthermore, overexpression of ip6k2 in mammalian cells enhanced the Hh pathway response, suggesting IP6K2 is a positive regulator of Hh signaling. Perturbations from IP6K2 depletion or TNP were reversed by overexpressing smoM2, gli1, or ip6k2. Moreover, the inhibitory effect of cyclopamine was reversed by overexpressing ip6k2. This identified roles for the inositol kinase pathway in early vertebrate development and tissue morphogenesis, and in Hh signaling. We propose that IP6K2 activity is required at the level or downstream of Smoothened but upstream of the transcription activator Gli1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980661"}
{"pmid": "20980662", "title": "Pineal-specific agouti protein regulates teleost background adaptation.", "content": "Pineal-specific agouti protein regulates teleost background adaptation. Background adaptation is used by teleosts as one of a variety of camouflage mechanisms for avoidance of predation. Background adaptation is known to involve light sensing by the retina and subsequent regulation of melanophore dispersion or contraction in melanocytes, mediated by α-melanocyte-stimulating hormone and melanin-concentrating hormone, respectively. Here, we demonstrate that an agouti gene unique to teleosts, agrp2, is specifically expressed in the pineal and is required for up-regulation of hypothalamic pmch and pmchl mRNA and melanosome contraction in dermal melanocytes in response to a white background. floating head, a mutant with defective pineal development, exhibits defective up-regulation of mch mRNAs by white background, whereas nrc, a blind mutant, exhibits a normal response. These studies identify a role for the pineal in background adaptation in teleosts, a unique physiological function for the agouti family of proteins, and define a neuroendocrine axis by which environmental background regulates pigmentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980662"}
{"pmid": "20980664", "title": "A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program.", "content": "A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program. Induced osteogenesis includes a program of microRNAs (miRs) to repress the translation of genes that act as inhibitors of bone formation. How expression of bone-related miRs is regulated remains a compelling question. Here we report that Runx2, a transcription factor essential for osteoblastogenesis, negatively regulates expression of the miR cluster 23a∼27a∼24-2. Overexpression, reporter, and chromatin immunoprecipitation assays established the presence of a functional Runx binding element that represses expression of these miRs. Consistent with this finding, exogenous expression of each of the miRs suppressed osteoblast differentiation, whereas antagomirs increased bone marker expression. The biological significance of Runx2 repression of this miR cluster is that each miR directly targets the 3' UTR of SATB2, which is known to synergize with Runx2 to facilitate bone formation. The findings suggest Runx2-negative regulation of multiple miRs by a feed-forward mechanism to cause derepression of SATB2 to promote differentiation. We find also that miR-23a represses Runx2 in the terminally differentiated osteocyte, representing a feedback mechanism to attenuate osteoblast maturation. We provide direct evidence for an interdependent relationship among transcriptional inhibition of the miR cluster by Runx2, translational repression of Runx2 and of SATB2 by the cluster miRs during progression of osteoblast differentiation. Furthermore, miR cluster gain of function (i.e., inhibition of osteogenesis) is rescued by the exogenous expression of SATB2. Taken together, we have established a regulatory network with a central role for the miR cluster 23a∼27a∼24-2 in both progression and maintenance of the osteocyte phenotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980664"}
{"pmid": "20980665", "title": "Informatics in radiology: an information model of the DICOM standard.", "content": "Informatics in radiology: an information model of the DICOM standard. The Digital Imaging and Communications in Medicine (DICOM) Standard is a key foundational technology for radiology. However, its complexity creates challenges for information system developers because the current DICOM specification requires human interpretation and is subject to nonstandard implementation. To address this problem, a formally sound and computationally accessible information model of the DICOM Standard was created. The DICOM Standard was modeled as an ontology, a machine-accessible and human-interpretable representation that may be viewed and manipulated by information-modeling tools. The DICOM Ontology includes a real-world model and a DICOM entity model. The real-world model describes patients, studies, images, and other features of medical imaging. The DICOM entity model describes connections between real-world entities and the classes that model the corresponding DICOM information entities. The DICOM Ontology was created to support the Cancer Biomedical Informatics Grid (caBIG) initiative, and it may be extended to encompass the entire DICOM Standard and serve as a foundation of medical imaging systems for research and patient care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980665"}
{"pmid": "20980668", "title": "APOE varepsilon2 and presymptomatic stage Alzheimer disease: how much is not enough?", "content": "APOE varepsilon2 and presymptomatic stage Alzheimer disease: how much is not enough?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980668"}
{"pmid": "20980667", "title": "A network approach to assessing cognition in disorders of consciousness.", "content": "A network approach to assessing cognition in disorders of consciousness. Conventional assessments of consciousness rely on motor responses to indicate awareness. However, overt behaviors may be absent or ambiguous in patients with disorders of consciousness (DOC) resulting in underrating capacity for cognition. fMRI during a silent picture-naming task was evaluated as an indicator of command following when conventional methods are not sufficient. A total of 10 patients with and without conventional evidence of awareness, who met diagnostic criteria for the minimally conscious state (MCS) (n = 5), vegetative state (VS) (n = 3), emerged from MCS (EMCS) (n = 1), and locked-in syndrome (LIS) (n = 1), participated in this observational fMRI study. The LIS and EMCS patients engaged a complete network of essential language-related regions during the object-naming task. The MCS and 2 of the VS patients demonstrated both complete and partial preservation of the object-naming system. Patients who engaged a complete network scored highest on the Coma Recovery Scale-Revised. This study supports the view that fMRI during object naming can elicit brain activations in patients with DOC similar to those observed in healthy subjects during command following, and patients can be stratified by completeness of the engaged neural system. These results suggest that activity of the language network may serve as an indicator of high-level cognition and possibly volitional processes that cannot be discerned through conventional behavioral assessment alone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980667"}
{"pmid": "20980666", "title": "Application of failure mode and effect analysis in a radiology department.", "content": "Application of failure mode and effect analysis in a radiology department. With increasing deployment, complexity, and sophistication of equipment and related processes within the clinical imaging environment, system failures are more likely to occur. These failures may have varying effects on the patient, ranging from no harm to devastating harm. Failure mode and effect analysis (FMEA) is a tool that permits the proactive identification of possible failures in complex processes and provides a basis for continuous improvement. This overview of the basic principles and methodology of FMEA provides an explanation of how FMEA can be applied to clinical operations in a radiology department to reduce, predict, or prevent errors. The six sequential steps in the FMEA process are explained, and clinical magnetic resonance imaging services are used as an example for which FMEA is particularly applicable. A modified version of traditional FMEA called Healthcare Failure Mode and Effect Analysis, which was introduced by the U.S. Department of Veterans Affairs National Center for Patient Safety, is briefly reviewed. In conclusion, FMEA is an effective and reliable method to proactively examine complex processes in the radiology department. FMEA can be used to highlight the high-risk subprocesses and allows these to be targeted to minimize the future occurrence of failures, thus improving patient safety and streamlining the efficiency of the radiology department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980666"}
{"pmid": "20980670", "title": "Can functional imaging assess consciousness in noncommunicative patients?", "content": "Can functional imaging assess consciousness in noncommunicative patients?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980670"}
{"pmid": "20980669", "title": "Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects.", "content": "Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects. To determine whether elderly normal APOE E2 (APOE2) carriers exhibit slower rates of hippocampal atrophy and memory decline compared to APOE3/3 carriers. We also determined whether APOE2 carriers have less Alzheimer pathology as reflected by CSF biomarkers. We included longitudinal data from 134 cognitively normal individuals (27 APOE2/2 or E2/3, 107 APOE3/3) from the Alzheimer's Disease Neuroimaging Initiative, a prospective cohort study. A linear mixed-effects model was used to determine how APOE2 affected rates of hippocampal atrophy and cognitive change over time. In a subsample of 72 individuals who also underwent CSF analysis, an ordinary least-squares regression was used to determine whether CSF β-amyloid (Aβ), total tau, and phosphorylated tau-181 (p-tau) differed by APOE2 status. APOE2 carriers demonstrated slower rates of hippocampal atrophy (p = 0.004). The mean rate of hippocampal atrophy among APOE2 carriers was -33 mm(3)/year (95% confidence interval -65 to +0.4), or -0.5%/year, compared to -86 mm(3)/year (95% confidence interval -102 to -71), or -1.3%/year, in the APOE3/3 group. No differences in the rates of episodic memory (p = 0.23) or overall cognitive change (p = 0.90) were detected. In the CSF subsample, APOE2 carriers had higher levels of CSF Aβ (p = 0.01), lower p-tau (p = 0.02), and marginally lower tau (p = 0.12). A slower rate of hippocampal atrophy in normal APOE2 carriers is consistent with the lower risk of Alzheimer disease in these individuals. We hypothesize that the slower atrophy rate is related to decreased preclinical Alzheimer pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980669"}
{"pmid": "20980671", "title": "Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5.", "content": "Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5. Trm5 is a eukaryal and archaeal tRNA methyltransferase that catalyzes methyl transfer from S-adenosylmethionine (AdoMet) to the N(1) position of G37 directly 3' to the anticodon. While the biological role of m(1)G37 in enhancing translational fidelity is well established, the catalytic mechanism of Trm5 has remained obscure. To address the mechanism of Trm5 and more broadly the mechanism of N-methylation to nucleobases, we examined the pH-activity profile of an archaeal Trm5 enzyme, and performed structure-guided mutational analysis. The data reveal a marked dependence of enzyme-catalyzed methyl transfer on hydrogen ion equilibria: the single-turnover rate constant for methylation increases by one order of magnitude from pH 6.0 to reach a plateau at pH 7.0. This suggests a mechanism involving proton transfer from G37 as the key element in catalysis. Consideration of the kinetic data in light of the Trm5-tRNA-AdoMet ternary cocrystal structure, determined in a precatalytic conformation, suggests that proton transfer is associated with an induced fit rearrangement of the complex that precedes formation of the reactive configuration in the active site. Key roles for the conserved R145 side chain in stabilizing a proposed oxyanion at G37-O(6), and for E185 as a general base to accept the proton from G37-N(1), are suggested based on the mutational analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980671"}
{"pmid": "20980672", "title": "Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis.", "content": "Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis. To better understand the compositional and structural dynamics of the human spliceosome during its activation, we set out to isolate spliceosomal complexes formed after precatalytic B but prior to catalytically active C complexes. By shortening the polypyrimidine tract of the PM5 pre-mRNA, which lacks a 3' splice site and 3' exon, we stalled spliceosome assembly at the activation stage. We subsequently affinity purified human B(act) complexes under the same conditions previously used to isolate B and C complexes, and analyzed their protein composition by mass spectrometry. A comparison of the protein composition of these complexes allowed a fine dissection of compositional changes during the B to B(act) and B(act) to C transitions, and comparisons with the Saccharomyces cerevisiae B(act) complex revealed that the compositional dynamics of the spliceosome during activation are largely conserved between lower and higher eukaryotes. Human SF3b155 and CDC5L were shown to be phosphorylated specifically during the B to B(act) and B(act) to C transition, respectively, suggesting these modifications function at these stages of splicing. The two-dimensional structure of the human B(act) complex was determined by electron microscopy, and a comparison with the B complex revealed that the morphology of the human spliceosome changes significantly during its activation. The overall architecture of the human and S. cerevisiae B(act) complex is similar, suggesting that many of the higher order interactions among spliceosomal components, as well as their dynamics, are also largely conserved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980672"}
{"pmid": "20980674", "title": "Conformational distributions at the N-peptide/boxB RNA interface studied using site-directed spin labeling.", "content": "Conformational distributions at the N-peptide/boxB RNA interface studied using site-directed spin labeling. In bacteriophage λ, interactions between a 22-amino acid peptide (called the N-peptide) and a stem-loop RNA element (called boxB) play a critical role in transcription anti-termination. The N-peptide/boxB complex has been extensively studied, and serves as a paradigm for understanding mechanisms of protein/RNA recognition. Particularly, ultrafast spectroscopy techniques have been applied to monitor picosecond fluorescence decay behaviors of 2-aminopurines embedded at various positions of the boxB RNA. The studies have led to a model in which the bound N-peptide exists in dynamic equilibrium between two states, with peptide C-terminal fragment either stacking on (i.e., the stacked state) or peeling away from (i.e., the unstacked state) the RNA loop. The function of the N-peptide/boxB complex seems to correlate with the fraction of the stacked state. Here, the N-peptide/boxB system is studied using the site-directed spin labeling technique, in which X-band electron paramagnetic resonance spectroscopy is applied to monitor nanosecond rotational behaviors of stable nitroxide radicals covalently attached to different positions of the N-peptide. The data reveal that in the nanosecond regime the C-terminal fragment of bound N-peptide adopts multiple discrete conformations within the complex. The characteristics of these conformations are consistent with the proposed stacked and unstacked states, and their distributions vary upon mutations within the N-peptide. These results suggest that the dynamic two-state model remains valid in the nanosecond regime, and represents a unique mode of function in the N-peptide/boxB RNA complex. It also demonstrates a connection between picosecond and nanosecond dynamics in a biological complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980674"}
{"pmid": "20980675", "title": "Biogenesis pathways of piRNAs loaded onto AGO3 in the Drosophila testis.", "content": "Biogenesis pathways of piRNAs loaded onto AGO3 in the Drosophila testis. PIWI-interacting RNAs (piRNAs) silence transposable elements in animal germ cells. In Drosophila ovaries, piRNAs are produced by two distinct pathways: the \"ping-pong\" amplification cycle that operates in germ cells and a ping-pong-independent pathway termed the primary pathway that mainly operates in somatic cells. AGO3, one of three PIWI proteins in flies, is involved in the ping-pong cycle in ovaries. We characterized AGO3-associated piRNAs in fly testes and found that like in ovaries, AGO3 functions in the ping-pong cycle with Aubergine (Aub) for piRNA production from transposon transcripts. In contrast, most AGO3-associated piRNAs corresponding to Suppressor of Stellate [Su(Ste)] genes are antisense-oriented and bound to Aub. In addition, the vast majority of AGO3-bound piRNAs derived from the AT-chX locus on chromosome X are antisense-oriented and are also found among Aub-associated piRNAs. The presence of very few sense Su(Ste) and AT-chX piRNAs suggests that biogenesis of both Su(Ste) and AT-chX piRNAs by a ping-pong mechanism only is highly unlikely. Nevertheless, the mutual interdependence of AGO3 and Aub for the accumulation of these piRNAs shows that their production relies on both AGO3 and Aub. Analysis of piRNA pathway mutants revealed that although the requirements for piRNA factors for Su(Ste)- and AT-chX-piRNA levels mostly overlap and resemble those for the ping-pong mechanism in the ovaries, Armitage (armi) is not required for the accumulation of AT-chX-1 piRNA. These findings suggest that the impacts of armi mutants on the operation of the piRNA pathway are variable in germ cells of fly testes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980675"}
{"pmid": "20980673", "title": "A balance between circular and linear forms of the dengue virus genome is crucial for viral replication.", "content": "A balance between circular and linear forms of the dengue virus genome is crucial for viral replication. The plasticity of viral plus strand RNA genomes is fundamental for the multiple functions of these molecules. Local and long-range RNA-RNA interactions provide the scaffold for interacting proteins of the translation, replication, and encapsidation machinery. Using dengue virus as a model, we investigated the relevance of the interplay between two alternative conformations of the viral genome during replication. Flaviviruses require long-range RNA-RNA interactions and genome cyclization for RNA synthesis. Here, we define a sequence present in the viral 3'UTR that overlaps two mutually exclusive structures. This sequence can form an extended duplex by long-range 5'-3' interactions in the circular conformation of the RNA or fold locally into a small hairpin (sHP) in the linear form of the genome. A mutational analysis of the sHP structure revealed an absolute requirement of this element for viral viability, suggesting the need of a linear conformation of the genome. Viral RNA replication showed high vulnerability to changes that alter the balance between circular and linear forms of the RNA. Mutations that shift the equilibrium toward the circular or the linear conformation of the genome spontaneously revert to sequences with different mutations that tend to restore the relative stability of the two competing structures. We propose a model in which the viral genome exists in at least two alternative conformations and the balance between these two states is critical for infectivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980673"}
{"pmid": "20980676", "title": "Modified least-variant set normalization for miRNA microarray.", "content": "Modified least-variant set normalization for miRNA microarray. MicroRNAs (miRNAs) are short noncoding RNAs that are involved in post-transcriptional regulation of mRNAs. Microarrays have been employed to measure global miRNA expressions; however, because the number of miRNAs is much smaller than the number of mRNAs, it is not clear whether traditional normalization methods developed for mRNA arrays are suitable for miRNA. This is an important question, since normalization affects downstream analyses of the data. In this paper we develop a least-variant set (LVS) normalization method, which was previously shown to outperform other methods in mRNA analysis when standard assumptions are violated. The selection of the LVS miRNAs is based on a robust linear model fit of the probe-level data that takes into account the considerable differences in variances between probes. In a spike-in study, we show that the LVS has similar operating characteristics, in terms of sensitivity and specificity, compared with the ideal normalization, and it is better than no normalization, 75th percentile-shift, quantile, global median, VSN, and lowess normalization methods. We evaluate four expression-summary measures using a tissue data set; summarization from the robust model performs as well as the others. Finally, comparisons using expression data from two dissimilar tissues and two similar ones show that LVS normalization has better operating characteristics than other normalizations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980676"}
{"pmid": "20980677", "title": "How I treat superficial venous thrombosis.", "content": "How I treat superficial venous thrombosis. Thrombosis of superficial veins has long been regarded as a benign disorder. If patients with a clinical diagnosis of superficial venous thrombosis (SVT) are thoroughly evaluated, the degree and extent of thrombosis in patients with SVT are characteristically underestimated (∼ 75% of the time) and such patients have coexistence (∼ 25% of the time) of, and/or rapid progression (∼ 10% of the time) to, systemic venous thromboembolism (VTE). Pulmonary embolism (PE; ∼ 25% of the time) and death (∼ 1% of the time) occur. Contributory risk factors for SVT are the same for VTE. Treatment of patients' SVT with parenteral anticoagulants appears to be both efficacious and certainly safe. I regard most patients with a clinical diagnosis of SVT the same as those with VTEs. Systemic anticoagulant therapy of patients with a clinical diagnosis of SVT obviates extensive imaging and laboratory workup and may be cost effective while encompassing treatment of any unknown concomitant thromboses with only low risk for hemorrhage. This decision is especially clear in those patients with known hypercoagulability. Patients without clinical risk factors are at lower risk to develop VTE complications and might be those who can be simply observed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980677"}
{"pmid": "20980678", "title": "Myeloperoxidase attracts neutrophils by physical forces.", "content": "Myeloperoxidase attracts neutrophils by physical forces. Recruitment of polymorphonuclear neutrophils (PMNs) remains a paramount prerequisite in innate immune defense and a critical cofounder in inflammatory vascular disease. Neutrophil recruitment comprises a cascade of concerted events allowing for capture, adhesion and extravasation of the leukocyte. Whereas PMN rolling, binding, and diapedesis are well characterized, receptor-mediated processes, mechanisms attenuating the electrostatic repulsion between the negatively charged glycocalyx of leukocyte and endothelium remain poorly understood. We provide evidence for myeloperoxidase (MPO), an abundant PMN-derived heme protein, facilitating PMN recruitment by its positive surface charge. In vitro, MPO evoked highly directed PMN motility, which was solely dependent on electrostatic interactions with the leukocyte's surface. In vivo, PMN recruitment was shown to be MPO-dependent in a model of hepatic ischemia and reperfusion, upon intraportal delivery of MPO and in the cremaster muscle exposed to local inflammation or to intraarterial MPO application. Given MPO's affinity to both the endothelial and the leukocyte's surface, MPO evolves as a mediator of PMN recruitment because of its positive surface charge. This electrostatic MPO effect not only displays a so far unrecognized, catalysis-independent function of the enzyme, but also highlights a principal mechanism of PMN attraction driven by physical forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980678"}
{"pmid": "20980679", "title": "RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity.", "content": "RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity. The molecular mechanisms regulating self-renewal of leukemia stem cells remain poorly understood. Here we report the generation of 2 closely related leukemias created through the retroviral overexpression of Meis1 and Hoxa9. Despite their apparent common origin, these clonal leukemias exhibit enormous differences in stem cell frequency (from 1 in 1.4, FLA2; to 1 in 347, FLB1), suggesting that one of these leukemias undergoes nearly unlimited self-renewal divisions. Using next-generation RNA-sequencing, we characterized the transcriptomes of these phenotypically similar, but biologically distinct, leukemias, identifying hundreds of differentially expressed genes and a large number of structural differences (eg, alternative splicing and promoter usage). Focusing on ligand-receptor pairs, we observed high expression levels of Sdf1-Cxcr4; Jagged2-Notch2/1; Osm-Gp130; Scf-cKit; and Bmp15-Tgfb1/2. Interestingly, the integrin beta 2-like gene (Itgb2l) is both highly expressed and differentially expressed between our 2 leukemias (∼ 14-fold higher in FLA2 than FLB1). In addition, gene ontology analysis indicated G-protein-coupled receptor had a much higher proportion of differential expression (22%) compared with other classes (∼ 5%), suggesting a potential role regulating subtle changes in cellular behavior. These results provide the first comprehensive transcriptome analysis of a leukemia stem cell and document an unexpected level of transcriptome variation between phenotypically similar leukemic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980679"}
{"pmid": "20980680", "title": "Regulation of steady-state neutrophil homeostasis by macrophages.", "content": "Regulation of steady-state neutrophil homeostasis by macrophages. The timely clearance of apoptotic neutrophils from inflammation sites is an important function of macrophages; however, the role of macrophages in maintaining neutrophil homeostasis under steady-state conditions is less well understood. By conditionally deleting the antiapoptotic gene cellular FLICE-like inhibitory protein (C-FLIP) in myeloid cells, we have generated a novel mouse model deficient in marginal zone and bone marrow stromal macrophages. These mice develop severe neutrophilia, splenomegaly, extramedullary hematopoiesis, decreased body weight, and increased production of granulocyte colony-stimulating factor (G-CSF) and IL-1β, but not IL-17. c-FLIP(f/f) LysM-Cre mice exhibit delayed clearance of circulating neutrophils, suggesting that failure of macrophages to efficiently clear apoptotic neutrophils causes production of cytokines that drive excess granulopoiesis. Further, blocking G-CSF but not IL-1R signaling in vivo rescues this neutrophilia, suggesting that a G-CSF-dependent, IL-1β-independent pathway plays a role in promoting neutrophil production in mice with defective clearance of apoptotic cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980680"}
{"pmid": "20980681", "title": "Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3.", "content": "Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3. We investigated possible cellular receptors for the human CXC chemokine platelet factor-4 variant/CXCL4L1, a potent inhibitor of angiogenesis. We found that CXCL4L1 has lower affinity for heparin and chondroitin sulfate-E than platelet factor-4 (CXCL4) and showed that CXCL10 and CXCL4L1 could displace each other on microvascular endothelial cells. Labeled CXCL4L1 also bound to CXCR3A- and CXCR3B-transfectants and was displaced by CXCL4L1, CXCL4, and CXCL10. The CXCL4L1 anti-angiogenic activity was blocked by anti-CXCR3 antibodies (Abs) in the Matrigel and cornea micropocket assays. CXCL4L1 application in CXCR3(-/-) or in wild-type mice treated with neutralizing anti-CXCR3 Abs, resulted in reduced inhibitory activity of CXCL4L1 on tumor growth and vascularization of Lewis lung carcinoma. Furthermore, CXCL4L1 and CXCL4 chemoattracted activated T cells, human natural killer cells, and human immature dendritic cells (DCs). Migration of DCs toward CXCL4 and CXCL4L1 was desensitized by preincubation with CXCL10 and CXCL11, inhibited by pertussis toxin, and neutralized by anti-CXCR3 Abs. Chemotaxis of T cells, natural killer cells, and DCs is likely to contribute to the antitumoral action. However, the in vivo data indicate that the angiostatic property of CXCL4L1 is equally important in retarding tumor growth. Thus, both CXCR3A and CXCR3B are implicated in the chemotactic and vascular effects of CXCL4L1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980681"}
{"pmid": "20980683", "title": "Metformin decreases GnRH- and activin-induced gonadotropin secretion in rat pituitary cells: potential involvement of adenosine 5' monophosphate-activated protein kinase (PRKA).", "content": "Metformin decreases GnRH- and activin-induced gonadotropin secretion in rat pituitary cells: potential involvement of adenosine 5' monophosphate-activated protein kinase (PRKA). Metformin is an insulin sensitizer molecule used for the treatment of infertility in women with polycystic ovary syndrome and insulin resistance. It modulates the reproductive axis, affecting the release of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH). However, metformin's mechanism of action in pituitary gonadotropin-secreting cells remains unclear. Adenosine 5' monophosphate-activated protein kinase (PRKA) is involved in metformin action in various cell types. Here, we investigated the effects of metformin on gonadotropin secretion in response to activin and GnRH in primary rat pituitary cells (PRP), and studied PRKA in rat pituitary. In PRP, metformin (10 mM) reduced LH and follicle-stimulating hormone (FSH) secretion induced by GnRH (10(-8) M, 3 h), FSH secretion, and mRNA FSHbeta subunit expression induced by activin (10(-8) M, 12 or 24 h). The different subunits of PRKA are expressed in pituitary. In particular, PRKAA1 is detected mainly in gonadotrophs and thyrotrophs, is less abundant in lactotrophs and somatotrophs, and is undetectable in corticotrophs. In PRP, metformin increased phosphorylation of both PRKA and acetyl-CoA carboxylase. Metformin decreased activin-induced SMAD2 phosphorylation and GnRH-induced mitogen-activated protein kinase (MAPK) 3/1 (ERK1/2) phosphorylation. The PRKA inhibitor compound C abolished the effects of metformin on gonadotropin release induced by GnRH and on FSH secretion and Fshb mRNA induced by activin. The adenovirus-mediated production of dominant negative PRKA abolished the effects of metformin on the FSHbeta subunit mRNA and SMAD2 phosphorylation induced by activin and on the MAPK3/1 phosphorylation induced by GnRH. Thus, in rat pituitary cells, metformin decreases gonadotropin secretion and MAPK3/1 phosphorylation induced by GnRH and FSH release, FSHbeta subunit expression, and SMAD2 phosphorylation induced by activin through PRKA activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980683"}
{"pmid": "20980682", "title": "Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle.", "content": "Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle. A region of the human von Willebrand factor (VWF) gene between -2812 and the end of the first intron (termed vWF2) was previously shown to direct expression in the endothelium of capillaries and a subset of larger blood vessels in the heart and skeletal muscle. Here, our goal was to delineate the DNA sequences responsible for this effect. A series of constructs containing deletions or mutations of vWF2 coupled to LacZ were targeted to the Hprt locus of mice, and the resulting animals were analyzed for reporter gene expression. The findings demonstrate that DNA sequences between -843 and -620 are necessary for expression in capillary but not large vessel endothelium in heart and skeletal muscle. Further, expression of VWF in capillaries and larger vessels of both tissues required the presence of a native or heterologous intron. In vitro assays implicated a role for ERG-binding ETS motif at -56 in mediating basal expression of VWF. In Hprt-targeted mice, mutation of the ETS consensus motif resulted in loss of LacZ expression in the endothelium of the heart and skeletal muscle. Together, these data indicate that distinct DNA modules regulate vascular bed-specific expression of VWF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980682"}
{"pmid": "20980684", "title": "The effects of estrogen and progesterone on blood glutamate levels: evidence from changes of blood glutamate levels during the menstrual cycle in women.", "content": "The effects of estrogen and progesterone on blood glutamate levels: evidence from changes of blood glutamate levels during the menstrual cycle in women. The gonadal steroids estrogen and progesterone have been shown to have neuroprotective properties against various neurodegenerative conditions. Excessive concentrations of glutamate have been found to exert neurotoxic properties. We hypothesize that estrogen and progesterone provide neuroprotection by the autoregulation of blood and brain glutamate levels. Venous blood samples (10 ml) were taken from 31 men and 45 women to determine blood glutamate, estrogen, progesterone, glucose, glutamate-pyruvate transaminase (GPT), and glutamate-oxaloacetate transaminase (GOT) levels, collected on Days 1, 7, 12, and 21 of the female participants' menstrual cycle. Blood glutamate concentrations were higher in men than in women at the start of menstruation (P < 0.05). Blood glutamate levels in women decreased significantly on Days 7 (P < 0.01), 12 (P < 0.001), and 21 (P < 0.001) in comparison with blood glutamate levels on Day 1. There was a significant decrease in blood glutamate levels on Days 12 (P < 0.001) and 21 (P < 0.001) in comparison with blood glutamate levels on Day 7. Furthermore, there was an increase in blood glutamate levels on Day 21 compared with Day 12 (P < 0.05). In women, there were elevated levels of estrogen on Days 7 (P < 0.05), 12, and 21 (P < 0.001), and elevated levels of progesterone on Days 12 and 21 (P < 0.001). There were no differences between men and women with respect to blood glucose concentrations. Concentrations of GOT (P < 0.05) and GPT (P < 0.001) were significantly higher in men than in women during the entire cycle. The results of this study demonstrate that blood glutamate levels are inversely correlated to levels of plasma estrogen and progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980684"}
{"pmid": "20980685", "title": "Follicular fluid high-density lipoprotein-associated sphingosine 1-phosphate (S1P) promotes human granulosa lutein cell migration via S1P receptor type 3 and small G-protein RAC1.", "content": "Follicular fluid high-density lipoprotein-associated sphingosine 1-phosphate (S1P) promotes human granulosa lutein cell migration via S1P receptor type 3 and small G-protein RAC1. Coordinated migration and progesterone production by granulosa cells is critical to the development of the corpus luteum, but the underlying mechanisms remain obscure. Sphingosine 1-phosphate (S1P), which is associated with follicular fluid high-density lipoprotein (FF-HDL), was previously shown to regulate ovarian angiogenesis. We herein examined the effects of S1P and FF-HDL on the function of granulosa lutein cells. Both FF-HDL and S1P induced migration of primary human granulosa lutein cells (hGCs) and the granulosa lutein cell line HGL5. In addition, FF-HDL but not S1P promoted progesterone synthesis, and neither of the two compounds stimulated proliferation of granulosa lutein cells. Polymerase chain reaction and Western blot experiments demonstrated the expression of S1P receptor type 1 (S1PR1), S1PR2, S1PR3, and S1PR5 but not S1PR4 in hGCs and HGL5 cells. The FF-HDL- and S1P-induced granulosa lutein cell migration was emulated by FTY720, an agonist of S1PR1, S1PR3, S1PR4, and S1PR5, and by VPC24191, an agonist of S1PR1 and S1PR3, but not by SEW2871 and phytosphingosine 1-phosphate, agonists of S1PR1 and S1PR4, respectively. In addition, blockade of S1PR3 with CAY1044, suramine, or pertussis toxin inhibited hGC and HGL5 cell migration toward FF-HDL or S1P, while blockade of S1PR1 and S1PR2 with W146 and JTE013, respectively, had no effect. Both FF-HDL and S1P triggered activation of small G-protein RAC1 and actin polymerization in granulosa cells, and RAC1 inhibition with Clostridium difficile toxin B or NSC23766 abolished FF-HDL- and S1P-induced migration. The FF-HDL-associated S1P promotes granulosa lutein cell migration via S1PR3 and RAC1 activation. This may represent a novel mechanism contributing to the development of the corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980685"}
{"pmid": "20980686", "title": "Survival and size are differentially regulated by placental and fetal PKBalpha/AKT1 in mice.", "content": "Survival and size are differentially regulated by placental and fetal PKBalpha/AKT1 in mice. The importance of placental circulation is exemplified by the correlation of placental size and blood flow with fetal weight and survival during normal and compromised human pregnancies in such conditions as preeclampsia and intrauterine growth restriction (IUGR). Using noninvasive magnetic resonance imaging, we evaluated the role of PKBalpha/AKT1, a major mediator of angiogenesis, on placental vascular function. PKBalpha/AKT1 deficiency reduced maternal blood volume fraction without affecting the integrity of the fetomaternal blood barrier. In addition to angiogenesis, PKBalpha/AKT1 regulates additional processes related to survival and growth. In accordance with reports in adult mice, we demonstrated a role for PKBalpha/AKT1 in regulating chondrocyte organization in fetal long bones. Using tetraploid complementation experiments with PKBalpha/AKT1-expressing placentas, we found that although placental PKBalpha/AKT1 restored fetal survival, fetal PKBalpha/AKT1 regulated fetal size, because tetraploid complementation did not prevent intrauterine growth retardation. Histological examination of rescued fetuses showed reduced liver blood vessel and renal glomeruli capillary density in PKBalpha/Akt1 null fetuses, both of which were restored by tetraploid complementation. However, bone development was still impaired in tetraploid-rescued PKBalpha/Akt1 null fetuses. Although PKBalpha/AKT1-expressing placentas restored chondrocyte cell number in the hypertrophic layer of humeri, fetal PKBalpha/AKT1 was found to be necessary for chondrocyte columnar organization. Remarkably, a dose-dependent phenotype was exhibited for PKBalpha/AKT1 when examining PKBalpha/Akt1 heterozygous fetuses as well as those complemented by tetraploid placentas. The differential role of PKBalpha/AKT1 on mouse fetal survival and growth may shed light on its roles in human IUGR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980686"}
{"pmid": "20980688", "title": "Polypyrimidine tract-binding protein 2 binds to selective, intronic messenger RNA and microRNA targets in the mouse testis.", "content": "Polypyrimidine tract-binding protein 2 binds to selective, intronic messenger RNA and microRNA targets in the mouse testis. Here we use an in vivo cross-linking and immunoprecipitation procedure to detect RNA targets of the multifunctional RNA-binding protein polypyrimidine tract-binding protein (PTBP) 2 in mouse testis. Eleven known mRNAs, including Ptbp2 mRNA, 28 RNAs matching intron sequences, and 12 small RNAs and repeat sequences are identified. The specificity of interaction between PTBP2 and its target RNAs was confirmed using RNA interference with mouse N2A cells. Reduction of PTBP2 levels led to decreases in 7 of 10 of the mRNAs, to the repression of alternative splicing of introns, and to reductions in specific miRNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980688"}
{"pmid": "20980689", "title": "The role of nutrition in the regulation of luteinizing hormone secretion by the opioidergic, dopaminergic, and serotonergic systems in female Mediterranean goats.", "content": "The role of nutrition in the regulation of luteinizing hormone secretion by the opioidergic, dopaminergic, and serotonergic systems in female Mediterranean goats. This study examined which neural mechanism (opioid, dopaminergic, or serotonergic system) is involved in the regulation of luteinizing hormone (LH) secretion, with and without nutritional modulation, at different times of the photoperiodic cycle. Goats were randomly distributed into two experimental groups that received either 1.1 (high group; n = 18) or 0.7 (low group; n = 18) times the nutritional maintenance requirements. The goats were exposed to alternations of 3 mo of long days and 3 mo of short days. Plasma LH concentrations were measured twice a week. The effects of intravenous injections of naloxone (endogenous opioid receptor antagonist), pimozide (dopaminergic(2) receptor antagonist), and cyproheptadine (serotonin 5-hydroxytryptamine(2) receptor antagonist) on LH secretion were assessed during challenges in three different photoperiodic situations: the onset of LH stimulation by short days (OnsetSD), the onset of LH inhibition by long days (OnsetLD), and during the LH inhibition by long days (LateLD). The role of the different neural systems was clearly modified by the level of nutrition. In the low-nutrition group, only naloxone increased LH concentrations during onsetLD (P < 0.05). However, in the high-nutrition group, naloxone increased the concentration and pulsatility of LH (P < 0.05) in onsetSD and onsetLD. Pimozide increased LH concentration and pulsatility (P < 0.05) in onsetLD and LH concentration in lateLD (P < 0.001). Finally, cyproheptadine significantly increased LH concentration at all three times (P < 0.001). These results provide evidence that all three systems are involved in the inhibition of LH release in onsetLD, and that the opioid and serotonin mechanisms are involved during the onsetSD that were enhanced by a high plane of nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980689"}
{"pmid": "20980690", "title": "Thrombophilic-type placental pathologies and skeletal growth delay following maternal administration of angiostatin4.5 in mice.", "content": "Thrombophilic-type placental pathologies and skeletal growth delay following maternal administration of angiostatin4.5 in mice. During placentation, the concentration of fibrinous deposits on the surfaces of maternal vasculature plays a role in villous development and has been strongly implicated in the pathophysiology of human fetal growth restriction (FGR). Fibrinous deposits are conspicuous sites of platelet aggregation where there is local activation of the hemostatic cascade. During activation of the hemostatic cascade, a number of pro- and antiangiogenic agents may be generated at the cell surface, and an imbalance in these factors may contribute to the placental pathology characteristic of FGR. We tested the hypothesis that angiostatin(4.5) (AS(4.5)), a cleavage fragment of plasminogen liberated at the cell surface, is capable of causing FGR in mice. Increased maternal levels of AS(4.5) in vivo result in reproducible placental pathology, including an altered vascular compartment (both in decidual and labyrinthine layers) and increased apoptosis throughout the placenta. In addition, there is significant skeletal growth delay and conspicuous edema in fetuses from mothers that received AS(4.5). Maternally generated AS(4.5), therefore, can access maternal placental vasculature and have a severe effect on placental architecture and inhibit fetal development in vivo. These findings strongly support the hypothesis that maternal AS(4.5) levels can influence placental development, possibly by directly influencing trophoblast turnover in the placenta, and contribute to fetal growth delay in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980690"}
{"pmid": "20980687", "title": "Asynchronous expression of the homeodomain protein CUX1 in Sertoli cells and spermatids during spermatogenesis in mice.", "content": "Asynchronous expression of the homeodomain protein CUX1 in Sertoli cells and spermatids during spermatogenesis in mice. The homeodomain CUX1 protein exists as multiple isoforms that arise from proteolytic processing of a 200-kDa protein or an alternate splicing or from the use of an alternate promoter. The 200-kDa CUX1 protein is highly expressed in the developing kidney, where it functions to regulate cell proliferation. Transgenic mice ectopically expressing the 200-kDa CUX1 protein develop renal hyperplasia associated with reduced expression of the cyclin kinase inhibitor p27. A 55-kDa CUX1 isoform is expressed exclusively in the testes. We determined the pattern and timing of CUX1 protein expression in developing testes. CUX1 expression was continuous in Sertoli cells from prepubertal testes but became cyclic when spermatids appeared. In testes from mature mice, CUX1 was highly expressed only in round spermatids at stages IV-V of spermatogenesis, in both spermatids and Sertoli cells at stages VI-X of spermatogenesis, and only in Sertoli cells at stage XI of spermatogenesis. While most of the seminiferous tubules in wild-type mice were between stages VI and X of spermatogenesis, there was a significant reduction in the percentage of seminiferous tubules between stages VI and X in Cux1 transgenic mice and a significant increase in the percentage of seminiferous tubules in stages IV-V and XI. Moreover, CUX1 was not expressed in proliferating cells in testes from either wild-type or transgenic mice. Thus, unlike the somatic form of CUX1, which has a role in cell proliferation, the testis-specific form of CUX1 is not involved in cell division and appears to play a role in signaling between Sertoli cells and spermatids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980687"}
{"pmid": "20980692", "title": "How desirable are your IC50s? A way to enhance screening-based decision making.", "content": "How desirable are your IC50s? A way to enhance screening-based decision making. Dose-response curves, resulting in estimates of endpoints such as the IC(50), are fundamental to drug discovery. However, some estimates are more reliable than others. It is important to know just how reliable an estimate is if we want to base decisions on it or use it in further modeling. In this study, the authors propose a new measure of endpoint reliability, based on the concept of desirability first introduced by Harrington. The solution is not dependent on the application used to analyze the experimental data, provided a number of parameters to characterize the dose-response curve are available. The authors show how this score can be used as an objective and consistent measure to rank screening results, combine information from groups of experiments, and determine optimal levels of characterization of a compound's biological activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980692"}
{"pmid": "20980691", "title": "IGF2 actions on trophoblast in human placenta are regulated by the insulin-like growth factor 2 receptor, which can function as both a signaling and clearance receptor.", "content": "IGF2 actions on trophoblast in human placenta are regulated by the insulin-like growth factor 2 receptor, which can function as both a signaling and clearance receptor. Insulin-like growth factor 2 (IGF2) enhances proliferation and survival of human first-trimester cytotrophoblasts (CTB) by signaling through the insulin-like growth factor 1 receptor (IGF1R). However, the role of the IGF2 receptor (IGF2R) in regulating trophoblast kinetics is unclear: It could act as a clearance receptor for trafficking excess ligand to lysosomes for degradation and/or directly mediate IGF2 signaling. We used an IGF2R knockdown strategy in BeWo cells and placental villous explants to investigate trophoblast proliferation and survival in response to stimulation by IGF. Both IGF1 and IGF2 significantly (P < 0.001) increased mitosis and reduced apoptosis in serum-starved BeWo cells. Small interfering RNA (siRNA)-mediated knockdown of IGF2R further enhanced IGF2-stimulated mitosis (P < 0.01), and IGF2-mediated rescue of apoptosis (P < 0.001) in these cells. Leu(27)IGF2, an IGF2 analogue that binds to IGF2R but not IGF1R, also protected IGF2R-expressing BeWo cells from apoptosis but did not increase mitosis. IGF treatment of term placental villous explants with reduced syncytial expression of IGF2R increased CTB proliferation (P < 0.001) and decreased apoptosis (P < 0.01) compared to untreated controls. Moreover, IGF2-mediated rescue of CTB apoptosis was significantly greater than that in tissue with normal IGF2R expression. Leu(27)IGF2 promoted mitogenesis and survival only in explants with intact IGF2R expression. Given that altered CTB turnover is observed in pregnancies complicated by fetal growth restriction, the development of strategies to manipulate the IGF2R signaling axis in the syncytiotrophoblast may provide a therapeutic avenue for treating this condition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980691"}
{"pmid": "20980694", "title": "ICOStomizing immunotherapies with T(H)17.", "content": "ICOStomizing immunotherapies with T(H)17. New insights on the role of costimulatory molecules in T helper cell function have yielded exciting alternatives to the development of therapeutic strategies that target T cell costimulatory pathways. Inducible costimulatory molecule (ICOS) signaling is now shown by Paulos and colleagues to support expansion of human T helper 17 (T(H)17) cells that could exert antitumor activity. Here we discuss (i) how these findings aid in our understanding of mechanisms that govern T(H)17 cell functions and (ii) the potential application of these new insights to the development of immunotherapies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980694"}
{"pmid": "20980695", "title": "The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells.", "content": "The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells. Human T helper 17 (T(H)17) cells regulate host defense, autoimmunity, and tumor immunity. Although cytokines that control human T(H)17 cell development have been identified, the costimulatory molecules important for T(H)17 cell generation are unknown. Here, we found that the inducible costimulator (ICOS) was critical for the differentiation and expansion of human T(H)17 cells. Human cord blood contained a subset of CD161(+)CD4(+) T cells that were recent emigrants from the thymus, expressed ICOS constitutively, and were imprinted as T(H)17 cells through ICOS signaling. ICOS stimulation induced c-MAF, RORC2, and T-bet expression in these cells, leading to increased secretion of interleukin-21 (IL-21), IL-17, and interferon-γ (IFN-γ) compared with cells stimulated with CD28. Conversely, CD28 ligation abrogated ICOS costimulation, dampening RORC2 expression while promoting the expression of the aryl hydrocarbon receptor, which led to reduced secretion of IL-17 and enhanced production of IL-22 compared with cells stimulated with ICOS. Moreover, ICOS promoted the robust expansion of IL-17(+)IFN-γ(+) human T cells, and the antitumor activity of these cells after adoptive transfer into mice bearing large human tumors was superior to that of cells expanded with CD28. The therapeutic effectiveness of ICOS-expanded cells was associated with enhanced functionality and engraftment in vivo. These findings reveal a vital role for ICOS signaling in the generation and maintenance of human T(H)17 cells and suggest that components of this pathway could be therapeutically targeted to treat cancer or chronic infection and, conversely, that interruption of this pathway may have utility in multiple sclerosis and other autoimmune syndromes. These findings have provided the rationale for designing new clinical trials for tumor immunotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980695"}
{"pmid": "20980696", "title": "Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy.", "content": "Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Breast cancer metastasis and disease recurrence are hypothesized to result from residual cancer stem cells, also referred to as tumor-initiating cells, which evade initial treatment. Using both syngeneic mouse and human xenograft models of triple-negative breast cancer, we have demonstrated that a subpopulation enriched in cancer stem cells was more resistant to treatment with 6 gray of ionizing radiation than the bulk of the tumor cells, and accordingly their relative proportion increased 48 to 72 hours after ionizing radiation treatment. In contrast, we achieved a larger reduction in tumor size without a concomitant increase in the percentage of cancer stem cells by treating with local hyperthermia for 20 minutes at 42°C after ionizing radiation using intravenously administered, optically activated gold nanoshells. Forty-eight hours after treatment, cells derived from the tumors treated with ionizing radiation plus hyperthermia exhibited both a marked decrease in tumorigenicity and a more differentiated phenotype than mock- and ionizing radiation-treated tumors. Thus, we have confirmed that these cancer stem cells are responsible for accelerated repopulation in vivo and demonstrated that hyperthermia sensitizes this cell population to radiation treatment. These findings suggest that local hyperthermia delivered by gold nanoshells plus radiation can eliminate radioresistant breast cancer stem cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980696"}
{"pmid": "20980698", "title": "Moving to place: childhood cancer treatment decision making in single-parent and repartnered family structures.", "content": "Moving to place: childhood cancer treatment decision making in single-parent and repartnered family structures. Few researchers have studied how parents from diverse family structures cope with childhood chronic illness. We designed this study to discern the childhood cancer treatment decision-making (TDM) process in these families. Using grounded theory, we interviewed 15 custodial parents, nonresidential parents, and stepparents who had previously made a major treatment decision for their children with cancer. \"Moving to place\" was the central psychosocial process by which parents negotiated involvement in TDM. Parents moved toward or were moved away from involvement based on parent position in the family (custodial, nonresidential, and stepparent), prediagnosis family dynamics, and time since diagnosis. Parents used the actions of stepping up, stepping back, being pushed, and stepping away to respond to the need for TDM. Parents faced additional stressors because of their family situations, which affected the TDM process. Findings from this study provide important insight into diverse families and their unique parental TDM experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980698"}
{"pmid": "20980697", "title": "Preserving the self: the process of decision making about hereditary breast cancer and ovarian cancer risk reduction.", "content": "Preserving the self: the process of decision making about hereditary breast cancer and ovarian cancer risk reduction. Women who carry BRCA1 or BRCA2 (BRCA1/2) gene mutations have up to an 88% lifetime risk of breast cancer and up to a 65% lifetime risk of ovarian cancer. Strategies to address these risks include cancer screening and risk-reducing surgery (i.e., mastectomy and salpingo-oophorectomy). We conducted a grounded theory study with 22 BRCA1/2 mutation-carrier women to understand how women make decisions about these risk-reducing strategies. Preserving the self was the overarching decision-making process evident in the participants' descriptions. This process was shaped by contextual conditions including the characteristics of health services, the nature of hereditary breast and ovarian cancer risk-reduction decisions, gendered roles, and the women's perceived proximity to cancer. The women engaged in five decision-making styles, and these were characterized by the use of specific decision-making approaches. These findings provide theoretical insights that could inform the provision of decisional support to BRCA1/2 carriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980697"}
{"pmid": "20980699", "title": "Examination of the factor structure and concurrent validity of the Langer Mindfulness/Mindlessness Scale.", "content": "Examination of the factor structure and concurrent validity of the Langer Mindfulness/Mindlessness Scale. Langer's theory of mindfulness proposes that a mindful person seeks out and produces novelty, is attentive to context, and is flexible in thought and behavior. In three independent studies, the factor structure of the Langer Mindfulness/Mindlessness Scale was examined. Confirmatory factor analysis failed to replicate the four-factor model and a subsequent exploratory factor analysis revealed the presence of a two-factor (mindfulness and mindlessness) solution. Study 2 demonstrated that the two factors assessed discrete constructs and were not merely products of acquiescence. Support was also found for a nine-item, one-factor model comprised solely of mindfulness items. On comparing models, Study 3 suggested the superiority of the one-factor mindfulness model. Finally, a preliminary investigation of the concurrent validity of the revised nine-item Langer Mindfulness/Mindlessness Scale is presented. The current article offers researchers a revised version of a mindfulness measure derived from a cognitive perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980699"}
{"pmid": "20980700", "title": "The Bermond-Vorst Alexithymia Questionnaire: a measurement invariance examination among U.S. Anglos and U.S. Hispanics.", "content": "The Bermond-Vorst Alexithymia Questionnaire: a measurement invariance examination among U.S. Anglos and U.S. Hispanics. The aim of this article is to assess the measurement invariance of the Bermond-Vorst Alexithymia Questionnaire (BVAQ) in U.S. Anglo (n = 490) and U.S. Hispanic ( n = 379) samples of college students. The BVAQ items demonstrated invariance of the factor loadings, the latent item intercepts, and unique factor variances. However, Hispanics had higher verbalizing scores and lower fantasizing scores on the latent variables. As a whole, the BVAQ requires additional testing and/or refinement for use with a Hispanic sample. Until such refinements, the authors recommend that the Toronto Alexithymia Scale-20 be used with U.S. Hispanic samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980700"}
{"pmid": "20980701", "title": "Corneal dystrophies: molecular genetics to therapeutic intervention--Fifth ARVO/Pfizer Ophthalmics Research Institute Conference.", "content": "Corneal dystrophies: molecular genetics to therapeutic intervention--Fifth ARVO/Pfizer Ophthalmics Research Institute Conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980701"}
{"pmid": "20980703", "title": "Inflammation in an individual joint predicts damage to that joint in psoriatic arthritis.", "content": "Inflammation in an individual joint predicts damage to that joint in psoriatic arthritis. The authors have previously reported on the relationship between activity and subsequent damage at the patient level for patients with psoriatic arthritis (PsA). The aim of this study was to identify key predictors of damage to individual joints in the hands and feet of patients with PsA, in particular those that capture previous activity. Data from patients followed prospectively at the University of Toronto PsA clinic between 1978 and 2006 were available for analysis. Logistic regression was used to relate the probability of a joint developing damage, within a specified time interval after the most recent clinic visit, to potential predictor variables. The predictor variables considered encompassed the history of disease activity of the joint and elsewhere, previous damage and the timing of clinical assessments. 511 patients with no hand damage at clinic entry and 552 patients with no foot damage at clinic entry were included in the analysis of the hand and foot joints, respectively. The analysis of the hand and foot joints demonstrated that the activity (tenderness and/or swelling) history of the specific joint is associated with subsequent damage. For the joints of the feet, activity observations elsewhere in the same foot, and in particular the same toe, were also shown to be associated with subsequent damage. Both joint tenderness and swelling are important predictors of joint damage in PsA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980703"}
{"pmid": "20980705", "title": "Vitamin D: an instrumental factor in the anti-phospholipid syndrome by inhibition of tissue factor expression.", "content": "Vitamin D: an instrumental factor in the anti-phospholipid syndrome by inhibition of tissue factor expression. Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterised by thrombosis, obstetric complications and the presence of anti-phospholipid antibodies such as anti-β2GPI-Abs. These antibodies may set off the coagulation cascade via several mechanisms, including the induction of tissue factor (TF) expression. Vitamin D has recently emerged as an immunomodulator that might exert an anti-thrombotic effect. Therefore, we studied serum vitamin D levels in a cohort of APS patients, as well as the effect of vitamin D in an in vitro model of APS-mediated thrombosis. Serum vitamin D levels were measured in 179 European APS patients and 141 healthy controls using the LIAISON chemiluminescent immunoassay, and the levels were evaluated in conjunction with a wide spectrum of clinical manifestations. In an vitro model, anti-β2GPI antibodies were purified from four patients with APS to evaluate the expression of TF in activated starved human umbilical vein endothelial cells. The effect of vitamin D (1,25-dihydroxyvitamin D, 10 nm) on anti-β2GPI-Abs mediated TF expression was analysed by immunoblot. Vitamin D deficiency (serum level ≤15 ng/ml) was documented in 49.5% of our APS patients versus 30% of controls (p<0.001) and was significantly correlated with thrombosis (58% vs 42%; p<0.05), neurological and ophthalmic manifestations, pulmonary hypertension, livedo reticularis and skin ulcerations. In vitro vitamin D inhibited the expression of TF induced by anti-β2GPI-antibodies. Vitamin D deficiency is common among APS patients and is associated with clinically defined thrombotic events. Vitamin D inhibits anti-β2GPI-mediated TF expression in vitro. Thus, vitamin D deficiency might be associated with decreased inhibition of TF expression and increased coagulation in APS. Evaluation of vitamin D status and vitamin D supplementation in APS patients should be considered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980705"}
{"pmid": "20980702", "title": "Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications.", "content": "Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980702"}
{"pmid": "20980706", "title": "Sociocognitive self-regulatory mechanisms governing judgments of the acceptability and likelihood of sport cheating.", "content": "Sociocognitive self-regulatory mechanisms governing judgments of the acceptability and likelihood of sport cheating. This study extends previous psychosocial literature (Bandura et al., 2001, 2003) by examining a structural model of the self-regulatory mechanisms governing the acceptability and likelihood of cheating in a sport context. Male and female adolescents (N = 804), aged 15-20 years, took part in this study. Negative affective self-regulatory efficacy influenced the acceptability and likelihood of cheating through the mediating role of moral disengagement, in females and males. Affective efficacy positively influenced prosocial behavior through moral disengagement or through resistive self-regulatory efficacy and social efficacy, in both groups. The direct effects of affective efficacy on beliefs about cheating were only evident in females. These results extend the findings of Bandura et al. (2001, 2003) to the sport context and suggest that affective and resistive self-regulatory efficacy operate in concert in governing adolescents' moral disengagement and transgressive behaviors in sport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980706"}
{"pmid": "20980704", "title": "Fcγ receptor IIIb polymorphism and use of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis.", "content": "Fcγ receptor IIIb polymorphism and use of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis. Infusion reaction is a major adverse event in patients with rheumatoid arthritis (RA) treated with infliximab. The possible factors including Fcγ receptor (FcγR) polymorphism associated with the development of infusion reactions in patients with RA receiving infliximab were prospectively examined. 96 patients with RA were enrolled and scheduled to receive infliximab at a dose of 3 mg/kg at weeks 0, 2 and 6 and every 8 weeks thereafter. Genetic polymorphisms for FcγR were examined in FCGR3A 176F/V and FCGR3B NA1/2 alleles by allele-specific PCR analysis. An infusion reaction was observed in 17 patients (18%) during 52 weeks of treatment with infliximab. The FCGR3B NA1/NA1 genotype was found in 75% of the patients with infusion reactions and in only 37% of those without (p=0.01), whereas the FCGR3A 176F/V genotype was equally distributed in the patients with or without infusion reactions. Glucocorticoids were used in 53% of the patients who developed an infusion reaction and in 80% of those without an infusion reaction (p=0.02). A multivariable logistic regression model showed that the FCGR3B NA1/NA1 genotype and use of glucocorticoids at baseline could be used as independent predictive factors for infusion reactions (OR 6.1 (95% CI 1.9 to 24.3) and OR 0.26 (95% CI 0.08 to 0.84), respectively). The presence of anti-infliximab antibody during infliximab treatment was also associated with infusion reactions. FCGR3B NA1/NA1 genotype, use of glucocorticoids and the presence of anti-infliximab antibody accounted for nearly all patients with RA who developed infusion reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980704"}
{"pmid": "20980707", "title": "How you provide corrective feedback makes a difference: the motivating role of communicating in an autonomy-supporting way.", "content": "How you provide corrective feedback makes a difference: the motivating role of communicating in an autonomy-supporting way. We relied on self-determination theory (SDT; Deci & Ryan, 2000) to investigate to what extent autonomy-supporting corrective feedback (i.e., feedback that coaches communicate to their athletes after poor performance or mistakes) is associated with athletes' optimal motivation and well-being. To test this hypothesis, we conducted a cross-sectional study with 337 (67.1% males) Greek adolescent athletes (age M = 15.59, SD = 2.37) from various sports. Aligned with SDT, we found through path analysis that an autonomy-supporting versus controlling communication style was positively related to future intentions to persist and well-being and negatively related to ill-being. These relations were partially mediated by the perceived legitimacy of the corrective feedback (i.e., the degree of acceptance of corrective feedback), and, in turn, by intrinsic motivation, identified regulation, and external regulation for doing sports. Results indicate that autonomy-supporting feedback can be still motivating even in cases in which such feedback conveys messages of still too low competence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980707"}
{"pmid": "20980708", "title": "Developmental activities that contribute to high or low performance by elite cricket batters when recognizing type of delivery from bowlers' advanced postural cues.", "content": "Developmental activities that contribute to high or low performance by elite cricket batters when recognizing type of delivery from bowlers' advanced postural cues. We examined the developmental activities that contribute to the development of superior anticipation skill among elite cricket batters. The batters viewed 36 video clips involving deliveries from bowlers that were occluded at ball release and were required to predict delivery type. Accuracy scores were used to create two subgroups: high-performing and low-performing anticipators. Questionnaires were used to record the participation history profiles of the groups. In the early stages of development, hours accumulated in cricket and other sports, as well as milestones achieved, did not differentiate groups. Significant between-group differences in activity profiles were found between 13 and 15 years of age, with high-performing anticipators accumulating more hours in structured cricket activity, and specifically in batting, compared with their low-performing counterparts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980708"}
{"pmid": "20980709", "title": "Cultural differences in the relationships among autonomy support, psychological need satisfaction, subjective vitality, and effort in British and Chinese physical education.", "content": "Cultural differences in the relationships among autonomy support, psychological need satisfaction, subjective vitality, and effort in British and Chinese physical education. Using basic psychological needs theory (BPNT; Ryan & Deci, 2000) as our guiding framework, we explored cultural differences in the relationships among physical education students' perceptions of teacher autonomy support, psychological need satisfaction, subjective vitality and effort in class. Seven hundred and fifteen students (age range from 13 to 15 years) from the U.K. and Hong Kong, China, completed a multisection inventory during a timetabled physical education class. Multilevel analyses revealed that the relationships among autonomy support, subjective vitality and effort were mediated by students' perceptions of psychological need satisfaction. The relationship between autonomy support and perceptions of competence was stronger in the Chinese sample, compared with the U.K. sample. In addition, the relationship between perceptions of relatedness and effort was not significant in the Chinese students. The findings generally support the pan-cultural utility of BPNT and imply that a teacher-created autonomy supportive environment may promote positive student experiences in both cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980709"}
{"pmid": "20980710", "title": "Momentary affect predicts bodily movement in daily life: an ambulatory monitoring study.", "content": "Momentary affect predicts bodily movement in daily life: an ambulatory monitoring study. There is converging evidence that physical activity influences affective states. It has been found that aerobic exercise programs can significantly diminish negative affect. Moreover, among healthy individuals, moderate levels of physical activity seem to increase energetic arousal and positive affect. However, the predictive utility of affective states for bodily movement has rarely been investigated. In this study, we examined whether momentarily assessed affect is associated with bodily movement in everyday life. Using a previously published data set (Schwerdtfeger, Eberhardt, & Chmitorz, 2008), we reanalyzed 12-hr ecological momentary assessment (EMA) data from 124 healthy volunteers. Electronic momentary positive-activated affect (EMA-PAA) and negative affect (EMA-NA) were assessed via handheld computers, and bodily movement was recorded via accelerosensors. Generalized linear mixed models were calculated. Results indicated that EMAPAA increases were accompanied by bodily movement increases of varying intensity. EMA-NA was also positively associated with increases in certain kinds of bodily movement. In light of previous research, this finding suggests that affect and bodily movement may have circular effects on each other.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980710"}
{"pmid": "20980711", "title": "Predictors of doping intentions in elite-level athletes: a social cognition approach.", "content": "Predictors of doping intentions in elite-level athletes: a social cognition approach. Doping use is an ongoing problem in contemporary sports. Despite efforts to detect and control doping, research on its etiology is limited, especially among elite-level athletes. The present study used an integrated social cognition model to examine the predictors of doping intentions. Structured anonymous questionnaires were completed by 1075 Greek adult elite-level athletes (M age = 25 years, SD = 5.89, 36.1% females) from both team and individual sports. Multiple regression and mediation analyses showed that attitudes, normative beliefs, situational temptation, and behavioral control significantly predicted doping intentions. A normative process was identified whereby situational temptation mediated the effects of normative beliefs on intentions. The findings provide the basis for future social cognition research in doping use, and set the framework for the development of evidence-based preventive interventions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980711"}
{"pmid": "20980713", "title": "Beyond sensation seeking: affect regulation as a framework for predicting risk-taking behaviors in high-risk sport.", "content": "Beyond sensation seeking: affect regulation as a framework for predicting risk-taking behaviors in high-risk sport. Sensation seeking has been widely studied when investigating individual differences in the propensity for taking risks. However, risk taking can serve many different goals beyond the simple management of physiological arousal. The present study is an investigation of affect self-regulation as a predictor of risk-taking behaviors in high-risk sport. Risk-taking behaviors, negative affectivity, escape self-awareness strategy, and sensation seeking data were obtained from 265 high-risk sportsmen. Moderated hierarchical regression analysis revealed significant main and interaction effects of negative affectivity and escape self-awareness strategy in predicting risk-taking behaviors: high-risk sportsmen's negative affectivity leads them to adopt risk-taking behaviors only if they also use escape self-awareness strategy. Furthermore, the affective model remained significant when controlling for sensation seeking. The present study contributes to an in-depth understanding of risk taking in high-risk sport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980713"}
{"pmid": "20980712", "title": "The exercise and affect relationship: evidence for the dual-mode model and a modified opponent process theory.", "content": "The exercise and affect relationship: evidence for the dual-mode model and a modified opponent process theory. This study examined the relationship between exertion level and affect using the framework of opponent-process theory and the dual-mode model, with the Activation-Deactivation Adjective Checklist and the State Anxiety Inventory among 14 active and 14 sedentary participants doing 20 min of treadmill exercise at speeds of 5% below, 5% above, and at lactate threshold (LT). We found a significant effect of time, condition, Time × Condition, and Time × Group, but no group, Group × Condition, or Time × Group × Condition effects, such that the 5% above LT condition produced a worsening of affect in-task compared with all other conditions whereas, across conditions, participants experienced in-task increases in energy and tension, and in-task decreases in tiredness and calmness relative to baseline. Posttask, participants experienced mood improvement (decreased tension, anxiety, and increased calmness) across conditions, with a 30-min delay in the above LT condition. These results partially support the dual-mode model and a modified opponent-process theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980712"}
{"pmid": "20980714", "title": "PathJam: a new service for integrating biological pathway information.", "content": "PathJam: a new service for integrating biological pathway information. Biological pathways are crucial to much of the scientific research today including the study of specific biological processes related with human diseases. PathJam is a new comprehensive and freely accessible web-server application integrating scattered human pathway annotation from several public sources. The tool has been designed for both (i) being intuitive for wet-lab users providing statistical enrichment analysis of pathway annotations and (ii) giving support to the development of new integrative pathway applications. PathJam&rsquo;s unique features and advantages include interactive graphs linking pathways and genes of interest, downloadable results in fully compatible formats, GSEA compatible output files and a standardized RESTful API.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980714"}
{"pmid": "20980715", "title": "Improved elimination of motion artifacts from a photoplethysmographic signal using a Kalman smoother with simultaneous accelerometry.", "content": "Improved elimination of motion artifacts from a photoplethysmographic signal using a Kalman smoother with simultaneous accelerometry. A photoplethysmography (PPG) signal provides very useful information about a subject's hemodynamic status in a hospital or ubiquitous environment. However, PPG is very vulnerable to motion artifacts, which can significantly distort the information belonging to the PPG signal itself. Thus, the reduction of the effects of motion artifacts is an important issue when monitoring the cardiovascular system by PPG. There have been many adaptive techniques to reduce motion artifacts from PPG signals. In the present study, we compared a method based on the fixed-interval Kalman smoother with the usual adaptive filtering algorithms, e.g. the normalized least mean squares, recursive least squares and the conventional Kalman filter. We found that the fixed-interval Kalman smoother reduced motion artifacts from the PPG signal most effectively. Therefore, the use of the fixed-interval Kalman smoother can reduce motion artifacts in PPG, thus providing the most reliable information that can be deduced from the reconstructed PPG signals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980715"}
{"pmid": "20980716", "title": "The removal of EMG in EEG by neural networks.", "content": "The removal of EMG in EEG by neural networks. In this paper, it is presented that electromyography (EMG) is a shot noise based on the generation of EMG. A novel filter is proposed by applying a neural network (NN) ensemble where the noisy input signal and the desired one are the same in a learning process. Both incremental and batch mode are applied in the learning process of NNs that is better than generalized NN filters. This NN ensemble filter not only reduces additive and multiplicative white noise inside signals, but also preserves the signals' characteristics. In clinical EEG and EMG signals processing, the filter is capable of reducing EMG in the clinical EEG, and it is proved that there is randomness in EMG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980716"}
{"pmid": "20980717", "title": "Factors influencing the mechanical behaviour of healthy human descending thoracic aorta.", "content": "Factors influencing the mechanical behaviour of healthy human descending thoracic aorta. In recent times, significant effort has been made to understand the mechanical behaviour of the arterial wall and how it is affected by the different vascular pathologies. However, to be able to interpret the results correctly, it is essential that the influence of other factors, such as aging or anisotropy, be understood. Knowledge of mechanical behaviour of the aorta has been customarily constrained by lack of data on fresh aortic tissue, especially from healthy young individuals. In addition, information regarding the point of rupture is also very limited. In this study, the mechanical behaviour of the descending thoracic aorta of 28 organ donors with no apparent disease, whose ages vary from 17 to 60 years, is evaluated. Tensile tests up to rupture are carried out to evaluate the influence of age and wall anisotropy. Results reveal that the tensile strength and stretch at failure of healthy descending aortas show a significant reduction with age, falling abruptly beyond the age of 30. This fact places age as a key factor when mechanical properties of descending aorta are considered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980717"}
{"pmid": "20980718", "title": "Post-traumatic stress disorder: a right temporal lobe syndrome?", "content": "Post-traumatic stress disorder: a right temporal lobe syndrome? In a recent paper (Georgopoulos et al 2010 J. Neural Eng. 7 016011) we reported on the power of the magnetoencephalography (MEG)-based synchronous neural interactions (SNI) test to differentiate post-traumatic stress disorder (PTSD) subjects from healthy control subjects and to classify them with a high degree of accuracy. Here we show that the main differences in cortical communication circuitry between these two groups lie in the miscommunication of temporal and parietal and/or parieto-occipital right hemispheric areas with other brain areas. This lateralized temporal-posterior pattern of miscommunication was very similar but was attenuated in patients with PTSD in remission. These findings are consistent with observations (Penfield 1958 Proc. Natl Acad. Sci. USA 44 51-66, Penfield and Perot 1963 Brain 86 595-696, Gloor 1990 Brain 113 1673-94, Banceaud et al 1994 Brain 117 71-90, Fried 1997 J. Neuropsychiatry Clin. Neurosci. 9 420-8) that electrical stimulation of the temporal cortex in awake human subjects, mostly in the right hemisphere, can elicit the re-enactment and re-living of past experiences. Based on these facts, we attribute our findings to the re-experiencing component of PTSD and hypothesize that it reflects an involuntarily persistent activation of interacting neural networks involved in experiential consolidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980718"}
{"pmid": "20980719", "title": "The initial appearance of the cranial nerves and related neuronal migration in staged human embryos.", "content": "The initial appearance of the cranial nerves and related neuronal migration in staged human embryos. The initial development of the cranial nerves was studied in 245 human embryos of stages 10-23 (4-8 postfertilizational weeks). Significant findings in the human embryo include the following. (1) Neuronal migration is a characteristic feature in the development of all the cranial nerves at stages 13-18, with the exception of the somatic efferent group. (2) The somatic efferent and the visceral efferent neurons are arranged respectively in ventrolateral and ventromedial columns (stages 13-17). (3) The ventrolateral column gives rise to somatic efferent nuclei; the neurons of the hypoglossal nerve develop rapidly and show a segmental organization as four roots that innervate three of the four occipital somites (stage 13); the abducent nucleus becomes displaced rostrally by a change in the rhombomeric pattern at stage 16. (4) The ventromedial column, originally continuous in rhombomeres 2-7, gives rise to visceral efferent and pharyngeal efferent nuclei. (5) All the 'true' cranial nerves (III-XII) are recognizable by stage 16. (6) In a primary migration the visceral efferent neurons proceed mediolaterally and accumulate dorsolaterally as nuclei (stages 13, 14); they differentiate into salivatory nuclei (stages 16, 17). (7) A secondary migration involves the pharyngeal efferent neurons (of nerves V and IX-XI), which also proceed mediolaterally and then form ventrolateral nuclei (stages 17, 18). (8) The facial complex shows a distinctive development in that its neural crest arises from the lateral wall of the neural folds/tube. Moreover, the migration of its pharyngeal efferent neurons is delayed, which may be related to the formation of the internal genu, and the motor nucleus begins to appear only at stage 23. (9) The sequence of appearance of afferent constituents is: cranial ganglia (stage 12), mesencephalic trigeminal nucleus (stage 15), vestibular nuclei (stages 18-22), and cochlear nuclei (stage 19). The unsatisfactory term special is avoided and the term pharyngeal for air-breathing vertebrates replaces branchial. The six functional categories used here are vestibulocochlear, somatic afferent, visceral afferent, visceral efferent, pharyngeal efferent, and somatic efferent, together with appropriate abbreviations. The cardiac and hypoglossal neural crests are included, and it is emphasized that all the ectodermal placodes develop within the 'ectodermal ring'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980719"}
{"pmid": "20980720", "title": "A randomized controlled trial of electrocoagulation-enabled biopsy versus conventional biopsy in the diagnosis of endobronchial lesions.", "content": "A randomized controlled trial of electrocoagulation-enabled biopsy versus conventional biopsy in the diagnosis of endobronchial lesions. Although electrocoagulation at time of endobronchial biopsy can potentially reduce procedure-related bleeding during fiberoptic bronchoscopy (FOB), it can also impair quality of tissue specimen; credible data for either are lacking. To evaluate the impact of hot biopsy on the quality of tissue samples and to quantify the amount of procedure-related bleeding during endobronchial biopsy. In this single-center, prospective, single-blind, randomized controlled study we included adult patients referred for FOB and having endobronchial lesions. Patients were randomized to bronchial biopsy using an electrocoagulation-enabled biopsy forceps, with (EC+ group) or without (EC- group) application of electrocoagulation current (40 W for 10 s in a monopolar mode). Procedure-related bleeding was semi-quantified by observer description, as well as through a visual analogue scale. Overall quality of biopsy specimen and tissue damage were assessed and graded by a pulmonary pathologist blinded to FOB details. 160 patients were randomized to endobronchial biopsy with (n = 81) or without (n = 79) the application of electrocoagulation. There were no severe bleeding episodes in either group, and severity of bleeding in the EC+ and EC- groups was similar (median visual analogue scale scores of 14 and 16, respectively). Histopathological diagnosis was similar in the EC+ and EC- groups (77.8% and 82.3%, respectively). There was no significant difference in tissue quality between the two groups. Use of electrocoagulation-enabled endobronchial biopsy does not alter specimen quality and does not result in any significant reduction in procedure-related bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980720"}
{"pmid": "20980721", "title": "p27kip1: a new multiple endocrine neoplasia gene?", "content": "p27kip1: a new multiple endocrine neoplasia gene? Multiple endocrine neoplasias (MEN) are autosomal dominant disorders characterized by the occurrence of tumors in at least two endocrine glands. Two types of MEN syndromes have long been known: MEN type 1 (MEN1) and MEN type 2 (MEN2), associated with a different spectrum of affected organs. MEN1 and MEN2 are caused by germline mutations in the MEN1 tumor suppressor gene and the RET proto-oncogene, respectively. Lately, a new type of MEN was identified (named MEN4) which is due to mutations in the CDKN1B gene, encoding for p27kip1 (p27), a cyclin-dependent kinase (Cdk) inhibitor that regulates the transition of cells from G1 to S phase. p27 is a non-canonical tumor suppressor since it is usually not somatically mutated in human cancers but it is often downregulated by post-translational mechanisms. The discovery of MEN4 has defined a new role for CDKN1B as a tumor susceptibility gene for multiple endocrine tumors. To date, six germline CDKN1B mutations have been found in patients with a MEN1-like phenotype but negative for MEN1 mutations. Due to the limited number of patients so far identified, the phenotypic features of MEN4 are not clearly defined. Here, we review the clinical and molecular characteristics of the MEN4 syndrome and summarize the main functions of p27 to better comprehend how their alteration can predispose to neuroendocrine tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980721"}
{"pmid": "20980722", "title": "Systemic and cellular reflections on ageing and the circadian oscillator: a mini-review.", "content": "Systemic and cellular reflections on ageing and the circadian oscillator: a mini-review. From circulation to digestion to excretion, a circadian clock synchronizes most aspects of mammalian physiology with the solar day. During normal ageing, this daily coordination gradually erodes, and during pathological ageing such erosion is exacerbated. Recent experiments suggest that therapies aimed at sustaining circadian function increase quality of life in elderly patients. Hence, a better understanding of the interactions between the circadian clock and ageing - at both cellular and systemic levels - could lead to direct benefits for aged individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980722"}
{"pmid": "20980723", "title": "Making decisions when no good choices exist: delivery of the survivor after intrauterine death of the co-twin in monochorionic twin pregnancies.", "content": "Making decisions when no good choices exist: delivery of the survivor after intrauterine death of the co-twin in monochorionic twin pregnancies. Infertility therapies have markedly increased the incidence of multiple pregnancies and concomitantly monozygotic twinning. In utero death of one monozygotic twin predisposes the survivor to death and serious morbidity from hemodynamic collapse, thromboplastins, or microemboli. The optimal management of such cases, however, is unclear. We compared single-twin demise to similar clinical conundrums in the past to try to derive a model for the data needed to reach a consensus. The management of such pregnancies is very controversial as the clinician must balance the risks of damage to the survivor by temporizing against the risks of prematurity and the possible futility of damage already having occurred because it is impossible to precisely time and document when the damage occurs. While there is not yet a standard consensus, the trend is towards more aggressive management either by rapid delivery or transfusion to ameliorate possible damage, but the risks are still very high for the survivor. The trend is moving towards more aggressive management than previously. We pose several questions that still remain to be answered to derive a consensus as to management, but it is unlikely that the required data could ever be obtained in a rigorous, randomized fashion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980723"}
{"pmid": "20980724", "title": "Efficacy of ustekinumab in palmoplantar psoriasis.", "content": "Efficacy of ustekinumab in palmoplantar psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980724"}
{"pmid": "20980725", "title": "Male bias in the song control system despite female bias in song rate in streak-backed orioles (Icterus pustulatus).", "content": "Male bias in the song control system despite female bias in song rate in streak-backed orioles (Icterus pustulatus). The song control system is a group of discrete interconnected nuclei found in the brains of all songbirds (suborder Passeri). Previous studies have reported a positive relationship between sex differences in song nucleus volumes and sex differences in song behavior across numerous songbird species, with species exhibiting greater sex differences in behavior also exhibiting greater sex differences in the brain. This body of comparative research, however, has failed to incorporate data from a bird species in which females sing more than males. In this study, we examine song nucleus volumes in both sexes of the streak-backed oriole (Icterus pustulatus), a New World blackbird with a female bias in song rate and similar song complexity between the sexes. Results from this neuroanatomical analysis are contrary to what was to be expected from previous research: despite the female bias in song rate, males have a significantly larger HVC and area X song nucleus volumes. Specifically, male HVC was 75% larger than that of females, and male area X was 64% larger than that of females. There was no significant sex difference in the size of the nucleus robustus arcopallialis. The lack of a positive relationship between song nuclei and singing behavior in these orioles demonstrates that our current understanding of song modulation via the song control system may be overly reliant on basic measures such as total volumes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980725"}
{"pmid": "20980726", "title": "Coagulation in vertebrates with a focus on evolution and inflammation.", "content": "Coagulation in vertebrates with a focus on evolution and inflammation. The evolution of a thrombin-generating system that produces a gelatinous clot to prevent the loss of blood occurred in parallel with the evolution of inflammatory responses that depend on bradykinin generation. Bioinformatics approaches that inventory the presence or absence of genes involved in these two processes support the view that both became progressively more complex during the period between the divergence of jawless fish and the appearance of mammals. Although the roots of both systems may extend to protochordates, they arose quite independently.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980726"}
{"pmid": "20980727", "title": "Gangrenous cystitis: report of a case and review of the literature.", "content": "Gangrenous cystitis: report of a case and review of the literature. Gangrenous cystitis is an extremely rare condition: only a total of 240 cases worldwide have been reported so far. Most of these cases have occurred in the preantibiotic era. After the advent and widespread use of antibiotics in clinical practice, only sporadic cases have been observed. We report a case of gangrenous cystitis in an 83-year-old woman who presented with symptoms of acute abdomen. The main causative factor was overdistension of the bladder due to urinary retention. The patient underwent total cystectomy and bilateral ureterocutaneostomy with a favorable outcome. The incidence, etiology, diagnosis, management and outcome of gangrenous cystitis are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980727"}
{"pmid": "20980728", "title": "Evolution of vertebrate hemostatic and inflammatory control mechanisms in blood-feeding arthropods.", "content": "Evolution of vertebrate hemostatic and inflammatory control mechanisms in blood-feeding arthropods. Arthropods evolved blood-feeding lifestyles on more than 20 independent occasions. A comparison of sialomes (secretory salivary gland protein family repertoires) corroborates this and indicates that unique protein families are found for different blood-feeding lineages. Closely related lineages considered to have evolved blood-feeding behavior independently might share similar sets of protein families in their sialomes. No orthologous relationships or conserved functional mechanisms have, however, been found for these apparently related protein family members. This implies that sialomes were already defined before the divergence of these related lineages, but that the functions involved in blood feeding evolved at a later stage. Protein families prone to lineage-specific expansion (gene duplication) tend to be abundant with specialized functions associated with various gene duplicates. A central theme that seems to emerge from comparative sialomic analysis is that of the convergent evolution of modulatory strategies that targets host defenses even if the molecular mechanisms differ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980728"}
{"pmid": "20980729", "title": "Circulating levels of allopregnanolone, a neuroactive steroid, and leptin during treatment with valproic acid in children with epilepsy.", "content": "Circulating levels of allopregnanolone, a neuroactive steroid, and leptin during treatment with valproic acid in children with epilepsy. Weight gain is a well-known unwanted effect of valproic acid (VPA) therapy. Studies on VPA-associated changes of homeostatic hormones remain limited and controversial. Allopregnanolone (AP) is a circulating neuroactive steroid involved in modulation of behavioral activities whose serum levels are increased in obese children. The aim of the present study was to determine whether VPA therapy affects leptin and AP circulating levels in prepubertal girls with epilepsy. One-hundred and one patients were divided into four groups: epileptic patients with VPA-associated obesity (n = 21); lean epileptic patients under VPA therapy (n = 35); healthy obese children (n = 23), and healthy lean children (n = 22). Patients with VPA-associated obesity had significantly enhanced blood concentrations of AP (p = 0.001) and leptin (p = 0.007) than lean subjects. There were no differences in leptin and AP plasma levels between patients with VPA-associated obesity and obese controls (p = 0.45 and p = 0.10, respectively), as there were no differences between lean patients under VPA therapy and lean healthy controls (p = 0.06). In patients under VPA therapy, both plasma leptin and AP levels were significantly correlated with BMI (r = 0.074, p = 0.02, and r = 0.084, p = 0.01, respectively). Plasma leptin concentrations were not correlated with AP levels (r = 0.023, p = 0.13). In conclusion, a correlation between obesity and neuroactive steroids was shown. It remains to be established whether the increased circulating level of AP is a secondary effect of anxiolytic-sedative processes occurring in subjects with obesity-related emotional and behavioral anomalies, or plays a central role in determining abnormal eating behaviors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980729"}
{"pmid": "20980730", "title": "Estrogen receptors and signaling pathways in lactotropes and somatotropes.", "content": "Estrogen receptors and signaling pathways in lactotropes and somatotropes. Estrogens are crucial determinants in the regulation of anterior pituitary function and maintenance of tissue homeostasis. Estrogen actions in this gland are exerted through both classical and non-classical mechanisms of action. This review summarizes the expression of classical α- and β-estrogen receptors and variant isoforms of estrogen receptors in anterior pituitary cell subpopulations. We also analyze estrogen receptor signaling pathways involved in estrogenic actions in the anterior pituitary gland, especially in lactotropes and somatotropes. Complex interactions between multiple signaling pathways are involved in estrogen regulation of hormone secretion, cell proliferation and cell death in this gland. Insight into these pituitary responses to estrogens would help to understand pituitary function and tumorigenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980730"}
{"pmid": "20980731", "title": "Maintaining and promoting mobility and functional independence in older adults.", "content": "Maintaining and promoting mobility and functional independence in older adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980731"}
{"pmid": "20980732", "title": "Laboratory review: the role of gait analysis in seniors' mobility and fall prevention.", "content": "Laboratory review: the role of gait analysis in seniors' mobility and fall prevention. Walking is a complex motor task generally performed automatically by healthy adults. Yet, by the elderly, walking is often no longer performed automatically. Older adults require more attention for motor control while walking than younger adults. Falls, often with serious consequences, can be the result. Gait impairments are one of the biggest risk factors for falls. Several studies have identified changes in certain gait parameters as independent predictors of fall risk. Such gait changes are often too discrete to be detected by clinical observation alone. At the Basel Mobility Center, we employ the GAITRite electronic walkway system for spatial-temporal gait analysis. Although we have a large range of indications for gait analyses and several areas of clinical research, our focus is on the association between gait and cognition. Gait analysis with walking as a single-task condition alone is often insufficient to reveal underlying gait disorders present during normal, everyday activities. We use a dual-task paradigm, walking while simultaneously performing a second cognitive task, to assess the effects of divided attention on motor performance and gait control. Objective quantification of such clinically relevant gait changes is necessary to determine fall risk. Early detection of gait disorders and fall risk permits early intervention and, in the best-case scenario, fall prevention. We and others have shown that rhythmic movement training such as Jaques-Dalcroze eurhythmics, tai chi and social dancing can improve gait regularity and automaticity, thus increasing gait safety and reducing fall risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980732"}
{"pmid": "20980733", "title": "Living environment and mobility of older adults.", "content": "Living environment and mobility of older adults. Older adults often elect to move into smaller living environments. Smaller living space and the addition of services provided by a retirement community (RC) may make living easier for the individual, but it may also reduce the amount of daily physical activity and ultimately reduce functional ability. With home size as an independent variable, the primary purpose of this study was to evaluate daily physical activity and physical function of community dwellers (CD; n = 31) as compared to residents of an RC (n = 30). In this cross-sectional study design, assessments included: the Continuous Scale Physical Functional Performance - 10 test, with a possible range of 0-100, higher scores reflecting better function; Step Activity Monitor (StepWatch 3.1); a physical activity questionnaire, the area of the home (in square meters). Groups were compared by one-way ANOVA. A general linear regression model was used to predict the number of steps per day at home. The level of significance was p < 0.05. Of the 61 volunteers (mean age: 79 ± 6.3 years; range: 65-94 years), the RC living space (68 ± 37.7 m(2)) was 62% smaller than the CD living space (182.8 ± 77.9 m(2); p = 0.001). After correcting for age, the RC took fewer total steps per day excluding exercise (p = 0.03) and had lower function (p = 0.005) than the CD. On average, RC residents take 3,000 steps less per day and have approximately 60% of the living space of a CD. Home size and physical function were primary predictors of the number of steps taken at home, as found using a general linear regression analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980733"}
{"pmid": "20980734", "title": "Age-related effects on postural control under multi-task conditions.", "content": "Age-related effects on postural control under multi-task conditions. Changes in postural sway and gait patterns due to simultaneously performed cognitive (CI) and/or motor interference (MI) tasks have previously been reported and are associated with an increased risk of falling in older adults. The objectives of this study were to investigate the effects of a CI and/or MI task on static and dynamic postural control in young and elderly subjects, and to find out whether there is an association between measures of static and dynamic postural control while concurrently performing the CI and/or MI task. A total of 36 healthy young (n = 18; age: 22.3 ± 3.0 years; BMI: 21.0 ± 1.6 kg/m(2)) and elderly adults (n = 18; age: 73.5 ± 5.5 years; BMI: 24.2 ± 2.9 kg/m(2)) participated in this study. Static postural control was measured during bipedal stance, and dynamic postural control was obtained while walking on an instrumented walkway. Irrespective of the task condition, i.e. single-task or multiple tasks, elderly participants showed larger center-of-pressure displacements and greater stride-to-stride variability than younger participants. Associations between measures of static and dynamic postural control were found only under the single-task condition in the elderly. Age-related deficits in the postural control system seem to be primarily responsible for the observed results. The weak correlations detected between static and dynamic measures could indicate that fall-risk assessment should incorporate dynamic measures under multi-task conditions, and that skills like erect standing and walking are independent of each other and may have to be trained complementarily.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980734"}
{"pmid": "20980735", "title": "The interplay between cognitive and motor functioning in healthy older adults: findings from dual-task studies and suggestions for intervention.", "content": "The interplay between cognitive and motor functioning in healthy older adults: findings from dual-task studies and suggestions for intervention. Reaching late adulthood is accompanied by losses in physical and mental resources, but lifestyle choices seem to have a considerable influence on the aging trajectory. This review deals with the interplay between cognitive and motor functioning in old age, focusing on two different lines of research, namely (a) dual-task studies requiring participants to perform a cognitive and a motor task simultaneously, and (b) intervention studies investigating whether increases in physical fitness also lead to improvements in cognitive performance. Dual-task studies indicate that healthy older adults show greater performance reductions in both domains than young adults when performing a cognitive and a motor task simultaneously. In addition, older adults often tend to protect their motor functioning at the expense of the cognitive task when the situation involves a threat to balance. This can be considered an adaptive behavior since fall-related injuries can have severe consequences. Fitness intervention studies which increased the aerobic fitness of previously sedentary older adults have demonstrated impressive performance improvements in the cognitive domain, especially for tasks involving executive control processes. These findings are interesting in light of cognitive intervention studies, which often fail to find significant transfer effects to tasks that have not been trained directly. The authors argue that future research should compare the effects of cognitive and aerobic fitness interventions in older adults, and they present a study design in which cognition and fitness are trained sequentially as well as simultaneously. Finally, methodological issues involved in this type of research and potential applications to applied settings are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980735"}
{"pmid": "20980736", "title": "Rationale for combined exercise and cognition-focused interventions to improve functional independence in people with dementia.", "content": "Rationale for combined exercise and cognition-focused interventions to improve functional independence in people with dementia. Evidence suggests that exercise and some cognition-focused intervention approaches can be used to elicit functional improvements in older people and, to some degree, those diagnosed with dementia. Independently, the two intervention types have been found to improve functional performance in people with dementia. The mechanisms underpinning these improvements come from comparable and diverse pathways. This suggests that it may be beneficial for the two intervention types to be coupled as part of regular care in individuals with a range of cognitive impairments. The aims of this review are threefold. The first aim is to present evidence to support the use for combining exercise and cognition-focused interventions. This will be achieved by reviewing the mechanisms of both approaches in improving functional performance in older people and in people with dementia and summarising recent progress. The increased risk of depression, falls and cardiovascular disease risk in people with dementia will also be highlighted. The second aim is to discuss the parameters of the two approaches that should be considered when combining them in terms of possible efficient models, especially in relation to exercise protocols as this is where the current literature shows the most promising outcomes. Maximisation of the efficacy of preventative and treatment interventions which focus on both cognitive functioning and physical health should lead to improving and extending functional independence. Key aspects of any combined intervention would involve the inclusion of both cardiovascular and other types of exercises, including falls reduction, and exercises addressing memory and executive function via goal setting in the real-life context. The third aim is to explore some of the issues that may arise when attempting to incorporate interventions into the regular treatment of people with dementia. Consideration must also be given to caregivers and the education of health professionals as well as to the mode of intervention itself. Further research is necessary in order to discern the most effective types of both intervention models. Provision of combined interventions might enhance the improvements in functional independence in people with dementia over and above the interventions being used separately.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980736"}
{"pmid": "20980738", "title": "The effect of PACAP38 on MyD88-mediated signal transduction in ischemia-/hypoxia-induced acute kidney injury.", "content": "The effect of PACAP38 on MyD88-mediated signal transduction in ischemia-/hypoxia-induced acute kidney injury. toll-like receptor 4 (TLR4) and its adaptor protein MyD88 play an important role in ischemia/reperfusion (I/R) injury in the kidney, and pituitary adenylate cyclase-activating polypeptide (PACAP) could ameliorate renal I/R injury. primary cultures of proximal tubule epithelial cells (PTEC) were prepared from wild-type and MyD88(-/-) mice, and subjected to hypoxia in vitro. Acute kidney injury (AKI) was induced by I/R in vivo in wild-type mice only. hypoxia resulted in significant increases in cytokine production and apoptosis/necrosis in wild-type PTEC, but these responses were markedly blunted in MyD88(-/-) PTEC. Treatment with PACAP38 before or after hypoxia further suppressed the hypoxia-induced cytokine responses and apoptosis in both MyD88(+/+) and MyD88(-/-) PTEC cultures. PACAP38 significantly inhibited TLR4/MyD88/TRAF6 as well as TRIF and IRF3 expression in mouse kidney and PTEC, and inhibited the secretion and mRNA expression of cytokines in kidneys from mice after I/R, paralleling the cytokine responses in vitro. Moreover, treatment with PACAP38 protected mice from renal failure, histological damage, neutrophil influx and tubule cell apoptosis after I/R. our data reveal that the TLR4-mediated cytokine responses to hypoxia are primarily dependent on MyD88 signaling and highlight the pivotal role of MyD88-dependent mechanisms in the coordination of the innate immune responses to ischemic/hypoxic acute renal tubular injury. The renoprotective effect of PACAP in AKI involves both MyD88-dependent and -independent pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980738"}
{"pmid": "20980737", "title": "Trophoblast glycoprotein: possible candidate mediating podocyte injuries in glomerulonephritis.", "content": "Trophoblast glycoprotein: possible candidate mediating podocyte injuries in glomerulonephritis. trophoblast glycoprotein (Tpbg), a 72-kDa transmembrane glycoprotein, is known to regulate the phenotypes of epithelial cells by modifying actin organization and cell motility. Recently, a microarray study showed that Tpbg is upregulated in Thy1 glomerulonephritis (Thy1 GN). We hypothesized that Tpbg regulates cytoskeletal rearrangement and modulates phenotypic alteration in podocytes under pathological conditions. we examined Tpbg expression in Thy1 GN and Tpbg function in mouse podocytes. we demonstrated that Tpbg is upregulated in the injured podocytes of Thy1 GN. In vitro, immunofluorescence studies revealed that Tpbg colocalized with the focal adhesion protein, vinculin, in parallel with stress fiber formation. This colocalization was observed even when actin filaments were depolymerized with cytochalasin D. Tpbg localization at focal adhesions was induced by dominant-active RhoA and suppressed by the ROCK1 inhibitor Y-26732. In addition, transforming growth factor-β increased Tpbg expression at focal adhesions concurrently with rearrangement of stress fibers. Stress fiber formation was suppressed in differentiated podocytes transfected with full-length Tpbg. Furthermore, knockdown of Tpbg using small interfering RNA decreased podocyte motility. our findings suggest a novel role of Tpbg in the phenotypic alteration of injured podocytes, and we accordingly propose a new mechanism of glomerular injury in glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980737"}
{"pmid": "20980740", "title": "Sequential bilateral cochlear implantation in children: development of the primary auditory abilities of bilateral stimulation.", "content": "Sequential bilateral cochlear implantation in children: development of the primary auditory abilities of bilateral stimulation. The advantages of sequential bilateral cochlear implantation were assessed in 29 children with a severe to profound hearing loss. The effect of age at second implantation and the effect of duration of bilateral implant use on the outcomes in speech perception and directional hearing were investigated. The children received their second cochlear implant at an age ranging from 2.8 to 8.5 years. Measurements were carried out preoperatively and postoperatively after 6, 12 and 24 months of bilateral implant use. A matched control group of 9 children with a unilateral implant were also measured over time and were compared with the study group after 12 and 24 months. Speech reception in both quiet and in noise and lateralization were measured. After 24 months, a minimum audible angle task was carried out. Bilateral advantages with regard to speech reception in quiet and in noise were already present after 6 months of bilateral implant use and improved thereafter. After 24 months, speech reception in noise had significantly improved with bilateral implants compared to that of children with a unilateral implant. The percentage of children that could accurately lateralize increased from 57% after 6 months to 83% after 24 months. With regard to the minimum audible angle task, loudspeakers were placed on average at ±42°. Age at second implantation did not have an influence on all outcomes. From the results it can be concluded that the advantages of bilateral hearing occur after sequential bilateral implantation and that age at second implantation does not influence the amount of bilateral advantage. Furthermore, it can be concluded that longer periods of bilateral implant use lead to greater bilateral advantages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980740"}
{"pmid": "20980739", "title": "Prevalence and prognosis of mild anemia in non-dialysis chronic kidney disease: a prospective cohort study in outpatient renal clinics.", "content": "Prevalence and prognosis of mild anemia in non-dialysis chronic kidney disease: a prospective cohort study in outpatient renal clinics. we evaluated prevalence and prognosis of mild anemia, defined as Hb (g/dl) 11-13.5 in males and 11-12 in females, in a prospective cohort of stage 3-5 chronic kidney disease (CKD) patients. we enrolled 668 consecutive patients in 25 renal clinics during 2003. Patients with frank anemia (Hb <11 or erythropoiesis-stimulating agents) at enrolment were excluded. Mild anemia was evaluated at two visits planned with an interval of 18 ± 6 months to identify four categories: no anemia at both visits, mild anemia at visit 1 resolving at visit 2 (RES), mild anemia persisting at both visits (PER), and progression from no anemia or mild anemia at visit 1 to mild or frank anemia at visit 2 (PRO). mild anemia was present in 41.3% at visit 1 and 34.1% at visit 2. We identified PER in 22% patients, RES in 10%, and PRO in 26%. In the subsequent 40 months, 125 patients developed end-stage renal disease (ESRD) and 94 died. At competing risk model, PER predicted ESRD (hazard ratio, HR, 1.82, 95% confidence interval, CI, 1.01-3.29) while PRO predicted both ESRD (HR 1.81, 95% CI 1.02-3.23) and death (HR 1.87, 95% CI 1.04-3.37). in non-dialysis chronic kidney disease, mild anemia is prevalent and it is a marker of risk excess when persistent or progressive over time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980739"}
{"pmid": "20980741", "title": "A pilot study of rituximab in immune-mediated inner ear disease.", "content": "A pilot study of rituximab in immune-mediated inner ear disease. Immune-mediated inner ear disease (IMED) is a cause of rapidly progressive auditory dysfunction. Patients are often responsive to high-dose corticosteroids and the disease is believed to be mediated by an antibody to inner ear proteins. To date, no therapies have proven effective as corticosteroid-sparing agents. Rituximab is a monoclonal antibody that depletes B cells, resulting in a reduction in autoantibody production. For that reason, rituximab was evaluated in a small pilot study in patients with IMED to see if there was a signal suggesting benefit. In all, 5/7 patients met the primary endpoint of an improvement in pure tone average (500-3000 Hz) by 10 dB in at least one ear, or an improvement in word identification score by at least 12% at 24 weeks, both relative to screening precorticosteroid values after 1 course of treatment. No significant adverse events were reported. The results of this study suggest further evaluation of rituximab as a treatment for IMED is indicated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980741"}
{"pmid": "20980742", "title": "Cochlear implants in forty-eight children with cochlear and/or vestibular abnormality.", "content": "Cochlear implants in forty-eight children with cochlear and/or vestibular abnormality. CT and MRI scans for 48 children with cochlear and/or vestibular abnormality were classified in decreasing severity; common cavity, Mondini plus enlarged vestibular aqueduct, Mondini dysplasia alone and enlarged vestibular aqueduct alone. No significant relationship between degree of cochlea abnormality and surgical issues (cerebrospinal fluid gusher, depth of insertion, number of electrodes) or speech perception/language outcomes was found. A significant relationship was observed between cerebrospinal fluid gusher and partial electrode insertion, fewer active electrodes and poorer sentence understanding. Optimum language outcomes were associated with younger age at implant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980742"}
{"pmid": "20980743", "title": "Pharmacokinetics of dexamethasone solution following intratympanic injection in guinea pig and sheep.", "content": "Pharmacokinetics of dexamethasone solution following intratympanic injection in guinea pig and sheep. Information on inner ear pharmacokinetics is limited in the literature, especially in large animals and in humans. A preliminary study was designed to explore the differences in inner ear exposure between guinea pigs and sheep following a single intratympanic injection of a 2% dexamethasone sodium phosphate solution. In both species, significant levels of dexamethasone were observed in the perilymph within 1 h, and decreasing by 50- to 100-fold within 12 h. Overall, the exposure to dexamethasone in the inner ear was significantly lower in sheep by 17- to 27-fold than in guinea pigs. Systemic and CNS exposure were minimal in both species as indicated by the low drug levels observed in plasma and CSF. Altogether, the preliminary evidence presented herein suggests the sheep as a practical and acceptable animal model to study the inner ear pharmacokinetics of drug candidates in large mammals and its potential towards extrapolation to human exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980743"}
{"pmid": "20980744", "title": "Proinflammatory activation of peripheral blood mononuclear cells in patients with vestibular neuritis.", "content": "Proinflammatory activation of peripheral blood mononuclear cells in patients with vestibular neuritis. Vestibular neuritis (VN) is characterized by acute vertigo with spontaneous nystagmus and is often accompanied by vegetative symptoms. While the pathogenetic process leading to this disease is widely unknown, increasing evidence exists that a proinflammatory environment is responsible for the induction and progression of VN. Twelve patients with acute VN and 12 healthy, age-matched individuals were included in this study. In addition to routine blood parameters, plasma levels of soluble CD40 receptor/ligand (sCD40/sCD40L) were determined by ELISA. Moreover, peripheral blood mononuclear cells (PBMCs) were isolated by Ficoll density gradient. Afterwards, in CD14 (monocytes), CD68 (macrophages), CD3 (T lymphocytes) or CD19 (B lymphocytes) subpopulations, proinflammatory [CD40, tumor necrosis factor-α (TNF-α), and COX-2], proapoptotic [caspase-3, and poly(adenosine diphosphate ribose) polymerase] and proadhesive (CD38) proteins were measured by 2-color fluorescence-activated cell sorter analyses. In comparison to healthy individuals, patients with acute VN revealed significantly elevated plasma levels of C-reactive protein, whereas plasma levels of sCD40 and sCD40L, as well as cholesterol/triglyceride status were similar. However, we found a significant elevation of the percentage of proinflammatory CD40+, TNF-α+, COX-2+ or CD38+ PBMCs. Elevation of proinflammatory and proadhesive proteins in PBMCs of patients with acute VN in parallel with an acute phase response may contribute to disease induction and progression and, thus, may be suggested as a novel therapeutic target.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980744"}
{"pmid": "20980745", "title": "Hyperventilation-induced nystagmus in patients with vestibular neuritis in the acute and follow-up stages.", "content": "Hyperventilation-induced nystagmus in patients with vestibular neuritis in the acute and follow-up stages. Our purposes were to characterize hyperventilation-induced nystagmus (HVIN) in patients with unilateral vestibular neuritis (VN) through follow-up examinations and to determine the effects of hyperventilation on vestibular imbalance in patients with VN. The horizontal eye movements in 35 patients with acute VN were recorded. The eye movements were analyzed and the maximum value of slow-phase eye velocity (SPV) was obtained during and after hyperventilation. Nineteen of 35 patients underwent follow-up examinations around 7 weeks later. When spontaneous nystagmus was present, the SPV of spontaneous nystagmus was subtracted from that of HVIN. A maximum SPV of HVIN of ≥4°/s was considered abnormal. The direction and SPV of HVIN were analyzed. The incidence of HVIN in patients with VN was significantly higher in the acute stage (18 of 35; 51%) than the follow-up stage (4 of 19; 21%). The direction of HVIN present in the follow-up stage was entirely towards the contralesional side (contralesional HVIN). However, the direction of HVIN in the acute stage was mixed, towards the contralesional side (10 of 35; 28%) and towards the ipsilesional side (8 of 35; 23%). The SPVs (49 ± 56°/s) of ipsilesional HVIN were significantly greater than the contralesional HVIN in the acute stage (8 ± 3°/s). Robust nystagmus (SPV ≥ 25°/s) was entirely ipsilesional HVIN, which was observed only in the acute stage. Our findings indicate that hyperventilation can result in aggravation of vestibular imbalance in the acute and follow-up stages in different ways. Hyperventilation resulted in contralesional HVIN in both the acute and follow-up stages, each in approximately a fourth of the patients, which suggests a disruption of central static compensatory mechanisms. However, ipsilesional HVIN was elicited only in the acute stage (in approximately a fourth of the patients). About half of the patients with ipsilesional HVIN showed robust responses, which is a characteristic finding, suggesting a transient intense increase in vestibular activity on the lesional side.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980745"}
{"pmid": "20980746", "title": "Proinflammatory and proadhesive activation of lymphocytes and macrophages in sudden sensorineural hearing loss.", "content": "Proinflammatory and proadhesive activation of lymphocytes and macrophages in sudden sensorineural hearing loss. Even though sudden sensorineural hearing loss (SHL) is a quite frequent disease, the pathogenetic processes leading to it are widely unknown. There is increasing evidence that immunomodulatory cells, especially T lymphocytes, might be involved. Twelve patients with acute SHL and 12 healthy, age-matched individuals were included in this study. In addition to routine blood parameters, plasma levels of tumor necrosis factor alpha (TNF-α), soluble CD40 (sCD40) and sCD40 ligand (sCD40L) were determined by ELISA. Moreover, peripheral blood mononuclear cells were isolated by Ficoll density gradient. Afterwards, in subpopulations--identified by CD14 (monocytes), CD68 (macrophages), CD3 (T lymphocytes) or CD19 (B lymphocytes) immunoreactivity--proinflammatory (CD40, TNF-α or cyclooxygenase-2) and proadhesive (CD38) proteins were measured by 2-color fluorescence-activated cell sorter analyses. In comparison with healthy individuals, patients with acute SHL revealed elevated plasma levels of sCD40 and sCD40L and a significantly decreased percentage (36%) of lymphocytes, especially of T lymphocytes (28%). Additionally, in patients with acute SHL the percentage of proinflammatory CD40, TNF-α, cyclooxygenase-2 or CD38-positive T or B lymphocytes was significantly increased. Our data suggest an enhanced extravasation of proadhesive and proinflammatory lymphocytes from the peripheral circulation, which may contribute to SHL disease induction as well as progression and, thus, may be suggested as a novel therapeutical target.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980746"}
{"pmid": "20980747", "title": "Post-stroke apathy and hypoperfusion in basal ganglia: SPECT study.", "content": "Post-stroke apathy and hypoperfusion in basal ganglia: SPECT study. Although apathy has been reported as one of the neuropsychiatric symptoms following stroke, there are few studies on regional cerebral blood flow (rCBF) in stroke patients with apathy. The present study compared rCBF between apathetic and non-apathetic patients after stroke. We recruited 102 patients with cerebral infarction within 1 month after stroke and performed neuropsychiatric assessments that included the apathy scale. rCBF was quantitatively measured using N-isopropyl-p-(123)I-iodoamphetamine single-photon emission computed tomography. Thirty-seven patients (36%) had apathy. The apathetic group showed lower cognitive function and a higher depressive state than the non-apathetic group. rCBF in the basal ganglia was reduced for the apathetic group compared with the non-apathetic group. Furthermore, lesions in the left basal ganglia were associated with hypoperfusion in bilateral basal ganglia and the presence of apathy. These findings demonstrate that apathy is a frequent symptom among stroke patients and that hypoperfusion caused by basal ganglia lesions may contribute to post-stroke apathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980747"}
{"pmid": "20980749", "title": "Stroke history and Chagas disease are independent predictors of silent cerebral microembolism in patients with congestive heart failure.", "content": "Stroke history and Chagas disease are independent predictors of silent cerebral microembolism in patients with congestive heart failure. Chagas disease is endemic in South and Central America, where 18 million individuals are infected by Trypanosoma cruzi, causing congestive heart failure (CHF) and cardioembolic stroke. Transcranial Doppler (TCD) is able to detect real-time microembolic signals (MES) to the brain vessels and may represent a surrogate marker of stroke risk. We aimed to determine predictors of MES in a population of patients with CHF. Consecutive CHF patients from a university-based cardiomyopathy clinic underwent TCD recording of the middle cerebral artery for 60 min by a single investigator who was blinded to all clinical data including cardiomyopathy etiology. Predictors of MES were sought by multivariable logistic regression analysis. From April 2004 to February 2009, 144 patients were studied, including 62 (44.6%) patients with Chagas disease. MES were detected in 9 (6.2%) patients and were more frequent in patients with Chagas disease than in patients with other causes of CHF (12.9 vs. 1.2%, p = 0.005). In multivariate analysis corrected for age and left-ventricular ejection fraction, predictors of MES were Chagas disease (odds ratio = 1.15, 95% confidence interval = 1.05-1.26, p = 0.004) and stroke history (odds ratio = 1.27, 95% confidence interval = 1.08-1.50, p = 0.005). Chagas disease and stroke history are risk factors for MES independent of cardiac disease severity. Other mechanisms besides structural cardiac disease may be operative, increasing embolic risk in Chagas disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980749"}
{"pmid": "20980748", "title": "Little association between intracranial arterial stenosis and lacunar stroke.", "content": "Little association between intracranial arterial stenosis and lacunar stroke. Atheromatous middle cerebral artery (MCA) stenosis could cause lacunar stroke by occluding lenticulostriate artery origins, but atheroma is common, and previous studies lacked suitable controls. We aimed to determine if intracranial atheroma was more common in lacunar than in cortical ischaemic stroke. We recruited patients with lacunar stroke and controls with mild cortical stroke, confirmed the stroke subtype with magnetic resonance imaging and used transcranial Doppler ultrasound imaging to record flow velocity and focal stenoses in the basal intracranial arteries 1 month after stroke. We compared ipsi- and contralateral MCA mean flow velocities between stroke subtypes and tested for associations using linear mixed models. Amongst 67 lacunar and 67 mild cortical strokes, mean age 64 and 67 years, respectively, we found no difference in MCA mean flow velocity between cortical and lacunar patients. Increasing age and white matter lesion scores were independently associated with lower MCA flow velocities (0.2 cms(-1) fall in velocity per year increase in age, p = 0.045; 3.75 cms(-1) fall in flow velocity per point increase in white matter lesion score, p = 0.004). We found no intracranial arterial stenoses. MCA atheromatous stenosis is unlikely to be a common cause of lacunar stroke in white populations. Falling velocities with increasing white matter lesion scores may reflect progressive brain tissue loss leaving less tissue to supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980748"}
{"pmid": "20980750", "title": "Stroke in asymptomatic Trypanosoma cruzi-infected patients.", "content": "Stroke in asymptomatic Trypanosoma cruzi-infected patients. The knowledge about the natural history of stroke in Chagas disease is incomplete. Vascular risk factors and stroke subtypes of asymptomatic Trypanosoma cruzi-infected patients with no clinical evidence of heart failure were assessed. They were compared with chronic chagasic cardiomyopathy patients who suffered a stroke and with a control group of 60 T. cruzi-noninfected stroke patients. Eighty-six consecutive chagasic stroke patients (mean age: 57.4 years; 64% females) were studied. 38.4% of chagasic stroke patients had asymptomatic T. cruzi infection. Smoking was more frequent in asymptomatic chagasic stroke patients (21.2 vs. 5.7%; p = 0.04). Prevalence of hypertension, diabetes and prior stroke was similar in both groups. Small-vessel infarction (15.6 vs. 3.8%) and large-vessel atherosclerosis (9.4 vs. 3.8%) were significantly more frequent in asymptomatic than in symptomatic T. cruzi-infected stroke patients (p = 0.001). Nevertheless, their frequency was even higher in T. cruzi-noninfected stroke patients (36.7 and 13.3%, respectively). Apical aneurysm (27.3%), left atrial dilatation (12.1%), left ventricle hypokinesia (9.4%) and right bundle branch block (36.4%) were also detected in asymptomatic T. cruzi-infected stroke patients. Ischemic stroke may be the first manifestation of Chagas disease in asymptomatic patients with mild left ventricle dysfunction. Other noncardioembolic stroke subtypes can occur in asymptomatic T. cruzi-infected patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980750"}
{"pmid": "20980751", "title": "Toll-like receptor 4 immunohistochemical expression is enhanced in macrophages of symptomatic carotid atherosclerotic plaques.", "content": "Toll-like receptor 4 immunohistochemical expression is enhanced in macrophages of symptomatic carotid atherosclerotic plaques. A growing body of evidence supports a role for Toll-like receptor 4 (TLR4), a primary receptor of the innate immune system, in atherosclerosis initiation and progression. Carotid atheroma macrophages (MACs) and smooth muscle cells (SMCs) express TLR4; nevertheless, correlations with epidemiological and clinical variables and especially cerebrovascular symptomatology remain unsettled. Carotid atherosclerotic plaques were obtained by standard carotid endarterectomy on 157 patients with carotid artery disease (84 asymptomatic - 73 symptomatic). TLR4 expression in MACs and SMCs of carotid atheroma was detected by immunohistochemistry techniques. TLR4 positivity, overexpression and intensity of immunostaining in MACs and SMCs were correlated with cerebrovascular symptomatology, epidemiological and clinical variables. MAC TLR4 positivity was noted in 129 (82.2%) patients. Patients receiving statins had significantly lower TLR4 expression. Rates of MAC TLR4 positivity were higher among symptomatic patients (odds ratio, OR = 5.1; 95% confidence interval, CI = 1.8-14.3; p < 0.001); the association was stronger for transient ischemic attacks. TLR4 overexpression was also significantly enhanced among symptomatic patients (OR = 2.3; 95% CI = 1.02-5.03; p < 0.05). No correlations were detected between SMC TLR4 expression and cerebrovascular symptoms. In multivariate models adjusting for age, gender, body mass index, hyperlipidemia and smoking, MAC TLR4 positivity was associated with a cerebrovascular event during the last 6 months (OR = 4; 95% CI = 1.2-13.3; p = 0.02). Symptomatic carotid artery plaques are characterized by increased expression of TLR4 in macrophages supporting a potential role for TLR4 in the pathophysiology and clinical presentation of cerebrovascular disease. Further investigation is warranted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980751"}
{"pmid": "20980752", "title": "Characteristics and outcome of ischemic stroke patients who are free of symptoms at 24 hours following thrombolysis.", "content": "Characteristics and outcome of ischemic stroke patients who are free of symptoms at 24 hours following thrombolysis. A part of ischemic stroke patients score 0 on the National Institutes of Health Stroke Scale (NIHSS) within 24 h following thrombolysis. Their clinical characteristics and long-term outcome are poorly studied. We report a single-center assessment of such patients. The cohort comprises 874 consecutive patients from the Helsinki Stroke Thrombolysis Registry, out of whom 113 scored 0 on 24-hour NIHSS. We analyzed their baseline demographic, clinical and radiological characteristics and 3-month outcome (modified Rankin Scale, mRS). Associations between the study parameters were tested by multivariate analysis. Patients with a 24-hour NIHSS score = 0 (n = 113) were younger than the rest of the population (n = 761; median: 65.6 vs. 71.5 years; p < 0.001), their NIHSS score on admission was lower (median: 5 vs. 10; p < 0.001), as was their glucose level (median: 6.2 vs. 6.7 mmol/l; p = 0.02). The onset-to-treatment time was similar in both groups (median: 120 vs. 115 min; p = 0.89). Patients with a 24-hour NIHSS score = 0 more often achieved an excellent outcome (mRS scores: 0-1; 81 vs. 31%; p < 0.001) and had lower mortality (1.8 vs. 11.8%; p < 0.01). One third of these patients had a brain infarction visible on 24-hour imaging. Lower baseline NIHSS score and younger age were independently associated with 24-hour NIHSS score = 0, which, in turn, was independently associated with excellent 3-month outcome. Patients with an NIHSS score = 0 at 24 h following thrombolysis are younger, have milder symptoms and have a lower glucose level on admission. They achieve more often excellent outcome and lower mortality. Still, 8% of them required help in daily activities or were dead at 3 months (mRS scores: 3-6).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980752"}
{"pmid": "20980754", "title": "Utility of the Kurashiki Prehospital Stroke Scale for hyperacute stroke.", "content": "Utility of the Kurashiki Prehospital Stroke Scale for hyperacute stroke. Our aim was to confirm the utility of paramedics using the Kurashiki Prehospital Stroke Scale (KPSS), with a maximum score of 13, for patients who may be eligible for administration of intravenous tissue plasminogen activator (IV t-PA). The subjects comprised acute stroke and transient ischemic attack (TIA) patients transferred to our hospital by paramedics. We analyzed correlations between KPSS and the National Institutes of Health Stroke Scale (NIHSS). Patients admitted within 3 h of onset were categorized into 2 groups: KPSS ≥4 and KPSS <4. We compared the proportion of patients receiving IV t-PA between the groups. Among 430 consecutive patients (mean age = 73 years; 266 men), paramedics recorded KPSS for 256 patients (59.5%). Excellent correlation was observed between KPSS and NIHSS in all 256 patients (R = 0.766; p < 0.001) and in 94 patients (ischemic stroke and TIA with symptoms on admission) admitted within 3 h of onset (R = 0.706; p < 0.001). Among these 94 patients, IV t-PA was more frequently given in the KPSS ≥4 group (30 of 58 patients, 51.7%) than in the KPSS <4 group (5 of 36 patients, 13.9%; p < 0.001). Arterial occlusion was more frequently observed in the KPSS ≥4 group (57.9 vs. 31.4%, p = 0.018). KPSS ≥4 was independently associated with administration of IV t-PA (odds ratio = 4.7; 95% confidence interval = 1.5-14.6, p = 0.008). Reliable concordance between KPSS and NIHSS was found in acute stroke and TIA patients. KPSS ≥4 represents a good score to indicate prospective t-PA patients among those admitted within 3 h of stroke onset.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980754"}
{"pmid": "20980753", "title": "Common carotid artery intima-media thickness: the Cardiovascular Risk Factor Multiple Evaluation in Latin America (CARMELA) study results.", "content": "Common carotid artery intima-media thickness: the Cardiovascular Risk Factor Multiple Evaluation in Latin America (CARMELA) study results. Measurement of far wall common carotid artery intima-media thickness (CCAIMT) has emerged as a predictor of incident cardiovascular events. The Cardiovascular Risk Factor Multiple Evaluation in Latin America (CARMELA) study was the first large-scale population-based assessment of both CCAIMT and cardiovascular risk factor prevalence in 7 Latin American cities; the relationship between CCAIMT and cardiovascular risk markers was assessed in these urban Latin American centers. CARMELA was a cross-sectional, population-based, observational study using stratified, multistage sampling. The participants completed a questionnaire, were evaluated in a clinical visit and underwent carotid ultrasonography. Clinical measurements were obtained by health personnel trained, certified and supervised by CARMELA investigators. Mannheim intima-media thickness consensus guidelines were followed for measurement of CCAIMT. In all cities and for both sexes, CCAIMT increased with higher age. CCAIMT was greater in the presence of cardiovascular risk factors than in their absence. In all cities, there was a statistically significant linear trend between increasing CCAIMT and a growing number of cardiovascular risk factors (p < 0.001). After adjustment for age and sex, metabolic syndrome was strongly associated with increased CCAIMT (p < 0.001 in all cities), as were hypercholesterolemia, obesity and diabetes (p < 0.001 in most cities). By multivariate analysis, hypertension was independently associated with an increase in CCAIMT in all cities (p < 0.01). CARMELA was the first large-scale population study to provide normal CCAIMT values according to age and sex in urban Latin American populations and to show CCAIMT increases in the presence of cardiovascular risk factors and metabolic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980753"}
{"pmid": "20980755", "title": "Do vascular risk factors explain the association between socioeconomic status and stroke incidence: a meta-analysis.", "content": "Do vascular risk factors explain the association between socioeconomic status and stroke incidence: a meta-analysis. Reduced socioeconomic status (SES) is associated with an increased risk of stroke, although the mechanism is not clear. It may be that those with lower SES have a greater burden of classic vascular risk factors. Our aim was to quantify the extent to which classic vascular risk factors explain the association between SES and stroke incidence. We conducted a systematic review and meta-analysis of studies examining the association of SES and stroke incidence, where classic vascular risk factors were considered. Searching MEDLINE, EMBASE and the Cochrane Library from 1980 onwards we identified 17 studies, 12 of these studies provided sufficient information to allow a meta-analysis. From each study the increased risk of stroke incidence, where the lowest socioeconomic category was compared with the highest, was recorded and pooled. The stroke incidence risks, adjusted for grouped classic risk factors, were also pooled. Review Manager 5 software was used for all analyses and results were analysed using hazard ratios (HR, 95% confidence interval, 95% CI) with a random effects model. Those with a lower SES were more likely to have a stroke (HR 1.67; 95% CI 1.46-1.91). Additional risk was reduced, but not eliminated, when classic vascular risk factors were adjusted for (HR 1.31; 95% CI 1.16-1.48). Low SES is associated with an increased risk of stroke that is partly explained by known classic vascular risk factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980755"}
{"pmid": "20980756", "title": "The dilemma of diastole.", "content": "The dilemma of diastole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980756"}
{"pmid": "20980757", "title": "Enamel erosion in dietary acids: inhibition by food proteins in vitro.", "content": "Enamel erosion in dietary acids: inhibition by food proteins in vitro. The aim of this study was to investigate the effects of two common food proteins on human enamel erosion in vitro. Erosion was measured by non-contact profilometry in citric, malic and lactic acids at pH 2.8, 3.2 and 3.8 and five commercially available soft drinks, in the presence of a salivary pellicle. Whole milk casein or hen egg ovalbumin was added to the acid solutions and drinks at 0.2% w/v, and the effect on erosion was determined by comparison with the corresponding solution without protein. Casein significantly reduced erosion in all but two solutions. The effects of the individual subfractions of casein in citric acid at pH 3.2 were similar to that of whole casein. Ovalbumin reduced erosion in some solutions, but the magnitude of the reduction was less than that with casein. A greater proportional reduction in erosion was seen in citric acid than in malic or lactic acids. We postulate that the mechanism involves adsorption of proteins to the pellicle or the enamel surface, forming a protein film with enhanced erosion-inhibiting properties. The citrate ion may play an active stabilising role, since erosion reduction was less in the other acids. In conclusion, casein and, to a lesser extent, ovalbumin show promise as potential anti-erosive additives to drinks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980757"}
{"pmid": "20980758", "title": "Review of effects of physical activity on strength, balance, mobility and ADL performance in elderly subjects with dementia.", "content": "Review of effects of physical activity on strength, balance, mobility and ADL performance in elderly subjects with dementia. Elderly individuals with dementia are vulnerable for a decline in physical functioning and basic activities of daily living (BADL) which can lead to a decline in autonomy and participation. This study reviews the effect of physical activity on physical functioning and BADL in elderly subjects with dementia. A systematic search of the literature was performed. Key words related to the elderly, dementia, exercise interventions and physical outcome measures were used. Sixteen studies were included. It was found that physical activity was beneficial in all stages of dementia. Multicomponent interventions (e.g. a combination of endurance, strength and balance) led to larger improvements in gait speed, functional mobility and balance, compared to progressive resistance training alone. BADL and endurance improved but were only assessed in multicomponent interventions. Lower-limb strength improved equally in multicomponent interventions and progressive resistance training. Multicomponent interventions can improve physical functioning and BADL in elderly subjects regardless of the stage of dementia. The best results were obtained in the interventions with the largest training volume. However, the small number of high-quality studies, and heterogeneity of the participants and interventions prevent us from drawing firm conclusions. Recommendations are given with respect to methodological issues, further research and practical guidelines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980758"}
{"pmid": "20980760", "title": "Restless legs syndrome and pregnancy: a questionnaire study in the Poitiers District, France.", "content": "Restless legs syndrome and pregnancy: a questionnaire study in the Poitiers District, France. To perform a large and detailed epidemiologic study on restless legs syndrome (RLS) during pregnancy in a European country. A cross-sectional questionnaire survey. The questionnaire was distributed by the medical staff in different outpatient waiting rooms (obstetrics and gynecology department of the university hospital, obstetrics and gynecology department of a private clinic, private midwives, private obstetrician-gynecologists, radiological centers before fetal ultrasound examination and general practitioners) in a French town and its surrounding area (200,000 inhabitants): A woman was considered affected if she met the International RLS Study Group criteria for RLS diagnosis. 1,022 pregnant women living in a French town were included. 24% of women were affected by RLS during their pregnancy. The disease was strongly related to the third trimester of pregnancy and had a significant impact on sleep leading to severe nocturnal and diurnal consequences with a high consumption of sleep medication. RLS affects one quarter of pregnant women, essentially during the third trimester and represents an important public health issue with sleep medication intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980760"}
{"pmid": "20980759", "title": "Cortical and non-cortical myoclonus of Creutzfeldt-Jakob disease.", "content": "Cortical and non-cortical myoclonus of Creutzfeldt-Jakob disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980759"}
{"pmid": "20980762", "title": "Stressed patients, stressed physicians and the need for mind-body medicine.", "content": "Stressed patients, stressed physicians and the need for mind-body medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980762"}
{"pmid": "20980761", "title": "Combined use of pulsed arterial spin-labeling and susceptibility-weighted imaging in stroke at 3T.", "content": "Combined use of pulsed arterial spin-labeling and susceptibility-weighted imaging in stroke at 3T. In acute stroke it is no longer sufficient to detect simply ischemia, but also to try to evaluate reperfusion/recanalization status and predict eventual hemorrhagic transformation. Arterial spin labeling (ASL) perfusion may have advantages over contrast-enhanced perfusion-weighted imaging (cePWI), and susceptibility weighted imaging (SWI) has an intrinsic sensitivity to paramagnetic effects in addition to its ability to detect small areas of bleeding and hemorrhage. We want to determine here if their combined use in acute stroke and stroke follow-up at 3T could bring new insight into the diagnosis and prognosis of stroke leading to eventual improved patient management. We prospectively examined 41 patients admitted for acute stroke (NIHSS >1). Early imaging was performed between 1 h and 2 weeks. The imaging protocol included ASL, cePWI, SWI, T2 and diffusion tensor imaging (DTI), in addition to standard stroke protocol. We saw four kinds of imaging patterns based on ASL and SWI: patients with either hypoperfusion and hyperperfusion on ASL with or without changes on SWI. Hyperperfusion was observed on ASL in 12/41 cases, with hyperperfusion status that was not evident on conventional cePWI images. Signs of hemorrhage or blood-brain barrier breakdown were visible on SWI in 15/41 cases, not always resulting in poor outcome (2/15 were scored mRS = 0-6). Early SWI changes, together with hypoperfusion, were associated with the occurrence of hemorrhage. Hyperperfusion on ASL, even when associated with hemorrhage detected on SWI, resulted in good outcome. Hyperperfusion predicted a better outcome than hypoperfusion (p = 0.0148). ASL is able to detect acute-stage hyperperfusion corresponding to luxury perfusion previously reported by PET studies. The presence of hyperperfusion on ASL-type perfusion seems indicative of reperfusion/collateral flow that is protective of hemorrhagic transformation and a marker of favorable tissue outcome. The combination of hypoperfusion and changes on SWI seems on the other hand to predict hemorrhage and/or poor outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980761"}
{"pmid": "20980763", "title": "Chelidonium majus--an integrative review: traditional knowledge versus modern findings.", "content": "Chelidonium majus--an integrative review: traditional knowledge versus modern findings. Chelidonium majus L. (family Papaveraceae), or greater celandine, is an important plant in western phytotherapy and in traditional Chinese medicine. Crude extracts of C. majus as well as purified compounds derived from it exhibit a broad spectrum of biological activities (antiinflammatory, antimicrobial, antitumoral, analgesic, hepatoprotective) that support some of the traditional uses of C. majus. However, herbal medicine also claims that this plant has several important properties which have not yet been scientifically studied: C. majus is supposed to have diuretic, antitussive and eye-regenerative effects. On the other hand, C. majus also has scientifically proven effects, e.g. anti-osteoporotic activity and radioprotection, which are not mentioned in traditional sources. Moreover, recent controversy about the hepatoprotective versus hepatotoxic effects of Chelidonium majus has renewed the interest of the medical community in this plant. This review is intended to integrate traditional ethno-medical knowledge and modern scientific findings about C. majus in order to promote understanding of its therapeutic actions as well as its toxic potential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980763"}
{"pmid": "20980764", "title": "Effects of homeopathic medicines on mood of adults with histories of coffee-related insomnia.", "content": "Effects of homeopathic medicines on mood of adults with histories of coffee-related insomnia. The purpose of this within-subjects feasibility study was to determine whether two different homeopathic remedies, Nux Vomica (NV) and Coffea Cruda (CC), exert effects on subjective mood ratings in healthy adults with a history of coffee-induced insomnia. The impact of individual personality traits, anxiety sensitivity or Type A cynical hostility, and homeopathic constitutional type (HTYPE-NV, HTYPE-CC), on remedy effects was examined to evaluate differential responsivity, in accord with clinical claims. Young adults of both sexes (ages 18-31) with above-average scores on standardized personality scales for either cynical hostility or anxiety sensitivity, and a history of coffee-induced insomnia, participated in the month-long study. At-home polysomnographic recordings were obtained on successive pairs of nights once per week for a total of 8 recordings (nights 1, 2, 8, 9, 15, 16, 22, 23). Subjects (N = 59) received placebo pellets on night 8 (single-blind) and verum pellets in 30c doses of one of two homeopathic remedies, NV or CC, on night 22 (doubleblind). Subjects completed the Profile of Mood States Scales at bedtime. The remedies produced differential effects on anger and overall mood, with improved mood following CC administration. A similar trend for depression was observed. Anxiety sensitive subjects experienced less tension following CC, whereas hostile subjects receiving CC became more tense. The high HTYPE-CC receiving CC experienced less vigor. The high HTYPE-CC receiving NV experienced more vigor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980764"}
{"pmid": "20980765", "title": "Are sham acupuncture interventions more effective than (other) placebos? A re-analysis of data from the Cochrane review on placebo effects.", "content": "Are sham acupuncture interventions more effective than (other) placebos? A re-analysis of data from the Cochrane review on placebo effects. A recent Cochrane review on placebo interventions for all kinds of conditions found that 'physical placebos' (which included sham acupuncture) were associated with larger effects over no-treatment control groups than 'pharmacological placebos'. We re-analyzed the data from this review to investigate whether effects associated with sham acupuncture differed from those of other 'physical placebos'. All trials included in the Cochrane review as investigating 'physical placebos' were classified as investigating either (sham) acupuncture or other physical placebos. The latter group was further subclassified into groups of similar interventions. Data from the Cochrane review were re-entered into the RevMan 5 software for meta-analysis. The primary analysis was a random-effects analysis of trials reporting continuous outcomes of trials that used either sham acupuncture or other physical placebos. Out of a total of 61 trials which reported a continuous outcome measure, 19 compared sham acupuncture and 42 compared other physical placebos with a no-treatment control group. The trials re-analyzed were highly heterogeneous regarding patients, interventions and outcomes measured. The pooled standardized mean difference was -0.41 (95% confidence interval -0.56, -0.24) between sham acupuncture and no treatment and -0.26 (95% CI -0.37, -0.15) between other physical placebos and no treatment (p value for subgroup differences = 0.007). Significant differences were also observed between subgroups of other physical placebos. Due to the heterogeneity of the trials included and the indirect comparison our results must be interpreted with caution. Still, they suggest that sham acupuncture interventions might, on average, be associated with larger effects than pharmacological and other physical placebos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980765"}
{"pmid": "20980766", "title": "Can you combine herbal therapy with physical agents in the treatment of venous leg ulcers? Evaluation of healing and antimicrobiological effects: a pilot study.", "content": "Can you combine herbal therapy with physical agents in the treatment of venous leg ulcers? Evaluation of healing and antimicrobiological effects: a pilot study. Venous leg ulcers are an important and common health problem. The aim of this study was to determine the effects of herbal therapies alone or in combination with physical therapy in the treatment of venous ulcers, as well as their antibacterial effects. Our study included 60 patients (3 groups, 20 patients each) with non-infected venous leg ulcers. The patients were treated with herbal therapy alone (group HTC), with a combination of electro-ionizing radiation and herbal therapy (group ERHT) or with a combination of polarized light and herbal therapy (group PLHT). Surface area and score of venous leg ulcers were followed clinically at baseline and at the end of 1, 3, 5, and 7 weeks of treatment. Comparing the results within the HTC, PLHT, and ERHT groups we found that the physical agents and herbal therapy significantly accelerated the healing of venous leg ulcers and reduced bacterial flora (p < 0.05). Comparing the results between the tested groups revealed no statistically significant difference (p > 0.05). Our results demonstrate healing and antibacterial effects of combined physical and herbal therapies, but no superiority of the combined treatment for venous leg ulcers as compared to treatment by herbal therapy alone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980766"}
{"pmid": "20980767", "title": "Topical treatment of necrotising herpes zoster with betulin from birch bark.", "content": "Topical treatment of necrotising herpes zoster with betulin from birch bark. Betulin, a pentacyclic triterpene, is the main constituent of the outer bark of birches (Betula alba). In recent years, anti-microbial, anti-inflammatory and differentiation-promoting effects of betulin have been described. A betulin-based emulsion without preservatives and detergent emulsifiers can be prepared from birch bark extract. We report the successful treatment with betulin emulsion of a severe necrotising herpes zoster in an immunosuppressed patient who had not responded to a conventional topical treatment. The betulin emulsion was directly applied to the wounds without causing any side effects. The presented case report demonstrates impressive skin tolerance and wound-healing properties of the betulin emulsion. These should be further evaluated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980767"}
{"pmid": "20980769", "title": "Person-centred medicine: towards a definition.", "content": "Person-centred medicine: towards a definition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980769"}
{"pmid": "20980768", "title": "Research initiatives in Europe.", "content": "Research initiatives in Europe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980768"}
{"pmid": "20980771", "title": "Early enteral fat supplementation with microlipid® and fish oil in the treatment of two premature infants with short bowel.", "content": "Early enteral fat supplementation with microlipid® and fish oil in the treatment of two premature infants with short bowel. The infusion of Intralipid® is a main risk factor for parenteral nutrition-associated cholestasis in infants with short bowel syndrome. Early provision of enteral fat to reduce the use of Intralipid while providing adequate fat for the growth of infants with short bowel has not been reported. We present 2 cases of premature infants with short bowel who received early supplementation of enteral Microlipid® and fish oil. This approach allowed us to discontinue Intralipid shortly after initiating feedings. The infants tolerated Microlipid/fish oil well without adverse reactions, had appropriate weight gain and ostomy output. They underwent bowel reanastomosis 3 weeks after enteral feeding began, and were discharged on full oral feedings. In case 1, the infant did not develop parenteral nutrition-associated cholestasis; in case 2, cholestasis had developed before initiating feeds, but was not aggravated by enteral fat and was improving prior to discharge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980771"}
{"pmid": "20980772", "title": "Standardized postnatal management of infants with congenital diaphragmatic hernia in Europe: the CDH EURO Consortium consensus.", "content": "Standardized postnatal management of infants with congenital diaphragmatic hernia in Europe: the CDH EURO Consortium consensus. Congenital diaphragmatic hernia (CDH) is associated with high mortality and morbidity. To date, there are no standardized protocols for the treatment of infants with this anomaly. However, protocols based on the literature and expert opinion might improve outcome. This paper is a consensus statement from the CDH EURO Consortium prepared with the aim of achieving standardized postnatal treatment in European countries. During a consensus meeting between high-volume centers with expertise in the treatment of CDH in Europe (CDH EURO Consortium), the most recent literature on CDH was discussed. Thereafter, 5 experts graded the studies according to the Scottish Intercollegiate Guidelines Network (SIGN) Criteria. Differences in opinion were discussed until full consensus was reached. The final consensus statement, therefore, represents the opinion of all consortium members. Multicenter randomized controlled trials on CDH are lacking. Use of a standardized protocol, however, may contribute to more valid comparisons of patient data in multicenter studies and identification of areas for further research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980772"}
{"pmid": "20980773", "title": "Fecal expression of human β-defensin-2 following birth.", "content": "Fecal expression of human β-defensin-2 following birth. Newborns display high intestinal permeability and a naive adaptive immune system, but infections are rare, indicating strong innate defense mechanisms. To measure the kinetics of fecal β-defensin-2 (HBD2), an inducible endogenous antimicrobial peptide produced by intestinal epithelial cells, in full-term and preterm infants. As a first step of this bicentric study, we enrolled 30 healthy full-term infants and 20 healthy preterm infants, with fecal samples collected at days 3, 7, 12 and 30 in full-term infants and at days 15, 30 and 60 in preterm infants. As a second step, we enrolled 10 preterm infants with intestinal distress, either necrotizing enterocolitis (NEC) Bell's stage III (n = 3) or isolated rectal bleeding (n = 7) and 20 controls, cross-matched for gestational age and age at sampling. HBD2 decreased significantly from day 3 to day 7 (227 ng/g; 14-440 vs. 117 ng/g; 30-470, p = 0.01) then moderately until day 30 (84 ng/g; 10-500) in healthy full-term infants. Healthy preterm infants showed similar high levels between days 15 and 60 (82 ng/g; 30-154 and 85 ng/g; 26-390, respectively). No significant variation of fecal HBD2 levels was observed between infants with clinical features of intestinal distress (77 ng/g, 2-1,271) and cross-matched controls (56 ng/g, 31-164). However, 2/3 infants with NEC and 1/7 infants with isolated rectal bleeding had HBD2 levels above the maximal level observed in controls. The kinetics of fecal HBD2 in the neonatal period indicate that this inducible defensin can be detected at high level in the feces of full-term and preterm infants, independently of gestational age or mode of feeding. The potential role of fecal HBD2 in detecting NEC is suggested.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980773"}
{"pmid": "20980774", "title": "Moderate physical training attenuates the effects of perinatal undernutrition on the morphometry of the splenic lymphoid follicles in endotoxemic adult rats.", "content": "Moderate physical training attenuates the effects of perinatal undernutrition on the morphometry of the splenic lymphoid follicles in endotoxemic adult rats. Physical training is a well-known inducer of positive physiological adaptations. The effects of moderate physical training on the morphometry of splenic lymphoid follicles of endotoxemic rats submitted to a perinatal low-protein (LP) diet were evaluated. Male Wistar rats were divided into two groups according to their mother's diet (17% casein, control, C) and, undernourished (8% casein, LP diet). On postnatal day 63, the animals were submitted to moderate physical training (8 weeks, 5 days·week⁻¹, 60 min·day⁻¹, at 70% of VO(₂max)). After the physical training period, half of each group received an injection of either lipopolysaccharide (LPS) or saline. Plasma corticosterone concentration, blood differential leukocyte counts and splenic morphometric parameters were analyzed. In undernourished toxemic (LP + LPS), LPS increased plasma corticosterone concentrations, but not in previously trained (LP + T + LPS) animals. Neutrophilia and lymphopenia in response to LPS was more pronounced in pups from undernourished mothers (LP + LPS). LP + LPS animals showed a higher increment (47.4%) in the number of lymphoid follicles, a reduction in the number and size of the splenic follicles, and in the marginal zone area. Those alterations were attenuated in trained animals (LP + T + LPS). Physical training attenuates the effects of nutritional programming on the splenic microanatomy by a mechanism that involves the hypothalamic-pituitary-adrenal axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980774"}
{"pmid": "20980775", "title": "Influence of cell cycle checkpoints and p53 function on the toxicity of temozolomide in human pancreatic cancer cells.", "content": "Influence of cell cycle checkpoints and p53 function on the toxicity of temozolomide in human pancreatic cancer cells. Though an increased efficacy of carmustine and temozolomide (TMZ) has been demonstrated by inactivation of O(6)-methylguanine-DNA methyltransferase (MGMT) with O(6)-benzyl-guanine (BG) in human pancreatic tumors refractive to alkylating agents, the regulatory mechanisms have not been explored. The effects of TMZ and BG on apoptosis, cell growth, the mitotic index, cell cycle distribution, and protein expression were studied by TUNEL, cell counting, flow cytometry, and Western blot analysis, respectively. The wt-p53 human pancreatic tumor cell line Capan-2 and p53-efficient mouse embryonic fibroblasts (MEFs) were more responsive to treatment with TMZ + BG than mutant p53 Capan-1 and p53-null MEFs. S phase delay with a subsequent G2/M arrest was observed in Capans in response to BG + TMZ. The G1-to-S transition delay in Capan-2 was associated with p53-dependent apoptosis and was distinctly different from the presumed mismatch repair (MMR) killing operative during the G2/M arrest. The effect of p53 on BG + TMZ toxicity was supported by a marked change in apoptosis when p53 function was restored/inactivated. There was an early induction of MMR proteins in p53-efficient lines. p53 provokes a classic proapoptotic response by delaying G1-to-S progression, but it may also facilitate cell killing by enhancing MMR-related cell cycle arrest and cell death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980775"}
{"pmid": "20980777", "title": "Chronic pancreatitis-like changes detected by endoscopic ultrasound in subjects without signs of pancreatic disease: do these indicate age-related changes, effects of xenobiotics, or early chronic pancreatitis?", "content": "Chronic pancreatitis-like changes detected by endoscopic ultrasound in subjects without signs of pancreatic disease: do these indicate age-related changes, effects of xenobiotics, or early chronic pancreatitis? The threshold number of endoscopic ultrasound (EUS) criteria for diagnosing chronic pancreatitis (CP) is variable. The presence of more than three abnormal ductular or parenchymal features is typically used, but the diagnostic significance of fewer EUS criteria is currently unclear. The aim of this study was to determine the prevalence of EUS features of CP in patients without pancreaticobiliary disease and to analyze the association with specific factors of interest. Over a 24-month period, 2,614 patients underwent EUS for an indication unrelated to pancreaticobiliary disease. Main outcome measurements wereunivariate and multivariate analysis between any EUS abnormality and demographic data and habits. 82 patients (16.8%) showed at least one ductular or parenchymal abnormality. 38 patients presented with only one abnormal feature, 26 patients with two, 12 patients with three, 4 patients with four, and 2 patients with five. Low-level alcohol consumption significantly increased the risk of hyperechoic parenchymal foci, main pancreatic duct (MPD) dilatation and wall hyperechogenicity. Smoking was associated with an increased risk of hyperechoic parenchymal foci. Male gender and advanced age were significantly associated with an increased risk of MPD dilatation. Long-term smoking and alcohol consumption, although at a low dose, induces CP-like changes. These abnormalities might represent either a clinically silent CP or a toxic effect of smoking and alcohol. Conversely, MPD dilation might represent a normal age-related variant or, alternatively, an effect of chronic low-level alcohol consumption. and IAP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980777"}
{"pmid": "20980776", "title": "Fatty acid composition of plasma lipid classes in chronic alcoholic pancreatitis.", "content": "Fatty acid composition of plasma lipid classes in chronic alcoholic pancreatitis. Supplementation of n-3 long-chain polyunsaturated fatty acids (LCPUFA) is considered as adjuvant therapy in acute pancreatitis. We investigated plasma fatty acid status in chronic pancreatitis (CP). Patients with alcoholic CP (n = 56, gender: 33/23 male/female, age: 60.0 [14.0] years (median [IQR]), who reported giving up alcohol consumption several years ago and 51 control subjects were included into the study. The fatty acid composition of plasma phospholipids (PL), triacylglycerols (TG) and sterol esters (STE) was analyzed. The sum of monounsaturated fatty acids was significantly higher in patients with CP than in controls (PL: 12.83 [3.35] vs. 12.20 [1.95], TG: 40.51 [6.02] vs. 37.52 [5.80], STE: 20.58 [7.22] vs. 17.54 [3.48], CP vs. control, % weight/weight, median [IQR], p < 0.05). Values of arachidonic acid were significantly lower in patients with CP than in controls (PL: 10.57 [3.56] vs. 11.66 [3.25], STE: 8.14 [2.63] vs. 9.24 [2.86], p < 0.05). Values of eicosapentaenoic acid and docosahexaenoic acid did not differ and there was no difference in the ratio of n-3 to n-6 LCPUFA. Our present data do not furnish evidence for the supplementation of n-3 LCPUFA to the diet of CP patients in relatively good clinical condition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980776"}
{"pmid": "20980778", "title": "Chronic alcohol intake increases the severity of pancreatitis induced by acute alcohol administration, hyperlipidemia and pancreatic duct obstruction in rats.", "content": "Chronic alcohol intake increases the severity of pancreatitis induced by acute alcohol administration, hyperlipidemia and pancreatic duct obstruction in rats. The mechanism of alcoholic pancreatitis is still unknown. It is of special interest why only about 5% of all alcoholics develop an episode of pancreatitis. We evaluated the role of long-term alcohol intake in the pathogenesis of alcoholic pancreatitis in rats. To evaluate the effect of long-term alcohol intake, rats were fed either a Lieber-DeCarli control diet (CD) or a Lieber-DeCarli alcohol diet (AD) for 6 weeks. Then, rats were infused over 2 h with either Ringer's solution (CO) or ethanol (E). In additional animals, alcoholic pancreatitis was induced by ethanol combined with hyperlipidemia and temporary pancreatic duct obstruction (EFO). Controls received Ringer's solution combined with hyperlipidemia and temporary pancreatic duct obstruction (RFO). Intravital microscopy (pancreatic perfusion and leukocyte adhesion), alcohol concentrations, amylase, lipase, cholesterine and triglyceride levels in plasma, myeloperoxidase activity and histology were evaluated at different time intervals. In those animals which received the Lieber-DeCarli control diet, capillary perfusion was reduced in the E group and further reduced in the EFO group as compared to the controls (CO, RFO; p < 0.01). Leukocyte adhesion was significantly increased in rats receiving E (p < 0.01), and was further increased in the combination group EFO (p < 0.01). EFO induced histologically evident acute pancreatitis. The additional administration of a long-term alcohol diet further increased microcirculatory disturbances and pancreatic injury significantly (EFO-AD > EFO-CD). This study shows that alcoholic pancreatitis is induced by the combination of ethanol and individual cofactors. Chronic alcohol abuse intensifies these changes. Therefore, long-term alcohol intake seems to be a major factor in the pathogenesis of alcoholic pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980778"}
{"pmid": "20980779", "title": "Effects of hydroxyethyl starch, gelatin and dextran on endothelium-derived relaxation in porcine coronary arteries.", "content": "Effects of hydroxyethyl starch, gelatin and dextran on endothelium-derived relaxation in porcine coronary arteries. In a pilot study we could show that hydroxyethyl starch (HES) induced a significant reduction of endothelium-dependent relaxation (EDR) and the endothelium-derived hyperpolarizing factor (EDHF). In this follow-up study we investigated whether this effect of HES was dose-dependent and whether it could be replicated with other colloids like dextran (DX) and gelatin (GL). Rings of fresh porcine coronary arteries were consecutively tested with or without HES, DX or GL (5, 10, or 20 mg/ml). Indomethacin was added in all measurements to eliminate prostacyclin effects. Prostaglandin F₂α was used for contraction and bradykinin (BK, 10⁻¹⁰ to 10⁻⁵ M) for inducing EDR. After blocking nitric oxide (NO) by N-nitro-L-arginine (L-NNA), the experiments were repeated to assess the EDHF-mediated relaxation response to BK. HES induced a reduction in EDR for the BK concentrations of 10⁻⁸ and 10⁻⁷ M (n = 10; p < 0.05). After NO blockage with L-NNA, the relaxation response was reduced especially for the BK concentrations of 10⁻⁶ and 10⁻⁵ M (p < 0.05). GL showed a reduction in EDR with or without NO blockage with L-NNA especially for the BK concentrations of 10⁻⁶ and 10⁻⁵ M (n = 14; p < 0.05). DX induced a significant reduction in EDR for the BK concentrations of 10⁻⁷ and 10⁻⁶ M (n = 12; p < 0.05). After NO blockage with L-NNA, the relaxation response was reduced especially for the BK concentrations of 10⁻⁶ and 10⁻⁵ M (p < 0.05). For clinically relevant concentrations of HES, DX and GL a significant reduction in both NO-induced and NO-/prostacyclin-independent EDR can be found in epicardial coronary arteries of the pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980779"}
{"pmid": "20980780", "title": "Effects of papaverine on twitches in mouse diaphragm.", "content": "Effects of papaverine on twitches in mouse diaphragm. This study examined the inhibitory effects of papaverine on twitches directly elicited by electrical stimulation of the mouse diaphragm. Papaverine (3-100 μM) inhibited twitches in a dose-dependent manner. Papaverine increased the cyclic adenosine monophosphate (cAMP) but not cyclic guanosine monophosphate (cGMP) content. IBMX, Db-cAMP and 8-br-cGMP did not affect twitches, whereas verapamil and NaCN inhibited twitches. Increases in extracellular Ca²+ removed the twitch inhibition caused by verapamil but not that caused by papaverine. Papaverine (30 and 100 μM) and NaCN (1 mM) decreased creatine phosphate and ATP contents. These results suggest that the relaxing effects of papaverine on mouse diaphragm are mainly due to inhibition of aerobic energy metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980780"}
{"pmid": "20980781", "title": "Contribution of cyclooxygenase-dependent mechanisms to contractile responses to donepezil in the rat urinary bladder.", "content": "Contribution of cyclooxygenase-dependent mechanisms to contractile responses to donepezil in the rat urinary bladder. Donepezil, an inhibitor of acetylcholinesterase, is used to improve cholinergic neurotransmission and cognitive function in Alzheimer's disease. In the present study, contractile effects of donepezil on the rat urinary bladder were examined and compared with those of the nonselective cholinesterase inhibitor neostigmine. Both donepezil and neostigmine produced concentration-dependent contractile responses of the isolated rat urinary bladder strips. The neostigmine-induced contractions were abolished by atropine. However, donepezil produced contractions of urinary bladders partly through atropine-insensitive mechanisms. The atropine-resistant component of donepezil-induced contraction was significantly reduced by the cyclooxygenase inhibitor indomethacin. These results suggest that cyclooxygenase-derived prostanoids contribute, at least in part, to contractile effects of donepezil in the rat urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980781"}
{"pmid": "20980783", "title": "Outcomes of empirical eating disorder phenotypes in a clinical female sample: results from a latent class analysis.", "content": "Outcomes of empirical eating disorder phenotypes in a clinical female sample: results from a latent class analysis. To empirically classify phenotypes of eating disorders (ED) using latent class analysis (LCA), and to validate this classification based on clinical outcomes. LCA was applied to 968 inpatients. The resultant classes were validated by clinical outcomes including mortality. A 5-class solution showed the best fit. The symptoms of latent class 1 (LC1; 26% of the sample) resembled anorexia nervosa (AN), bingeing-purging (AN-B/P) subtype; those of LC2 (23%) resembled bulimia nervosa; those of LC3 (11%) were close to AN-B/P without weight and body concerns; those of LC4 resembled restrictive anorexia nervosa (RAN) without weight and body concerns, and those of LC5 RAN. A history of hospitalization for ED was significantly more frequent for LC3 and LC4. The lowest BMI at admission were presented in LC4. LC1 showed the highest level of psychological disturbances and LC4 the lowest. LC3 and LC4 differed from LC1 and LC5 by higher percentages of treatment dropout (64.9 vs. 57.2 and 55.7 vs. 47.5%, respectively; overall p = 0.001). Survival rates tended to be different between the LC (p = 0.09). Subgroups of AN patients with low weight and body concerns seem more severe at hospitalization and more difficult to manage, with a higher rate of treatment dropout than the 'typical' AN patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980783"}
{"pmid": "20980782", "title": "Differential responses to emotional interference in paranoid schizophrenia and bipolar mania.", "content": "Differential responses to emotional interference in paranoid schizophrenia and bipolar mania. Studies on emotional biases towards threat-related stimuli in schizophrenia and bipolar disorder have provided, so far, inconsistent results. The aim of the present study was to investigate emotional interference in acute schizophrenic and manic patients and its clinical correlates by using a card version of the Emotional Stroop Task designed with neutral, paranoid, depressive and manic words. Thirty paranoid schizophrenia patients, 30 manic patients and 60 healthy controls were compared on the Emotional Stroop Test. Response times (RT) were collected for each card. Interference indices were calculated by subtracting the RT for the neutral card from the RT for the depressive, paranoid and manic cards. The schizophrenic and manic patient groups showed an increased interference effect when the emotional valence was relating to the disorder-specific psychopathology. In addition, the paranoid interference index correlated with positive symptoms in schizophrenic patients. By contrast, no correlation was evidenced between interference indices and mood symptoms in the manic group. Among schizophrenic patients, paranoid interference might be a state-related emotional abnormality associated with persecutory delusions. In mania, we suggest that emotional biases towards depressive as well as manic information might be trait features of the emotional hyperreactivity involved in the vulnerability to bipolar disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980782"}
{"pmid": "20980784", "title": "The relationship between personality organization and psychiatric classification in chronic pain patients.", "content": "The relationship between personality organization and psychiatric classification in chronic pain patients. The present study investigated the relationship between psychiatric classification and personality organization (PO) in a secondary/tertiary clinical sample of chronic pain patients (CPPs). Forty-three patients were administered the Structured Clinical Interview for DSM-IV (SCID I+II) and the Structured Interview of Personality Organization (STIPO). The prevalence of axis I and axis II disorders was correlated with the STIPO level of PO. The STIPO dimensional ratings of patients without personality disorder (PD) were compared to those of patients diagnosed with one or more PDs. Axis I comorbidity was high (93%), and 63% of the patients met the criteria for at least one axis II diagnosis. Twenty-five patients (58%) were diagnosed as borderline PO, with high-level impairments in the dimensions 'coping/rigidity', 'primitive defenses' and 'identity'. Higher axis I and axis II comorbidity corresponded with greater severity of PO impairment. No difference was found between the dimensional ratings of patients without PD and those of patients with one or more PDs. The assessment of PO is a crucial issue for diagnosis and treatment planning in CPPs, since it represents a measure of structural impairment that is to a considerable extent independent of axis I and II diagnoses. Moreover, the STIPO dimensional rating focuses on the most salient dysfunctions at a given time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980784"}
{"pmid": "20980785", "title": "Gender, depressive symptoms and patterns of alcohol use among college students.", "content": "Gender, depressive symptoms and patterns of alcohol use among college students. Serious alcohol-related negative consequences are associated with a number of drinking behaviors among college students. Thus, it is critical to identify students who are at greater risk for hazardous drinking. Although some studies have shown that depressive symptoms may be associated with alcohol use in this population, findings are not consistent. The current study extends previous research by investigating the relationship between depressive symptoms, daily alcohol use and compulsive drinking among college students and whether gender moderates these relationships. The participants were 904 college students (495 females; mean age = 20.07 ± 1.85 years) who filled out questionnaires that focused on drinking behaviors and severity of depressive symptoms. Gender moderated the relationship between depressive symptoms and daily alcohol consumption. In male college students, worse depressive symptoms were associated with increased daily alcohol use and with greater risk for compulsive drinking. In female college students, worse depressive symptoms increased the risk for compulsive drinking, but not for greater daily alcohol use. Results suggest that prevention programs aimed at decreasing harmful alcohol use among college students must take into consideration the role of both gender and depressive symptoms in the development of problematic drinking behaviors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980785"}
{"pmid": "20980786", "title": "Childhood trauma and psychopathology among alcohol-dependent men: no interaction with temperament and character.", "content": "Childhood trauma and psychopathology among alcohol-dependent men: no interaction with temperament and character. The aim of this study was to evaluate possible interactions between childhood trauma, temperament, character, and psychopathology among alcohol-dependent men. Participants were 156 alcohol-dependent men consecutively admitted to a dependency treatment unit. The Childhood Abuse and Neglect Questionnaire, the Temperament and Character Inventory, and the Symptom Checklist-Revised were administered to all participants. Childhood abuse and neglect did not have any effect on temperament and character scores in multivariate analysis. Whereas childhood abuse had a significant main effect on all types of clinical psychopathology except depression and psychoticism scores, childhood neglect only had a significant main effect on depression scores. There was no interaction between childhood abuse and neglect on these analyses. Among alcohol-dependent men, childhood abuse and neglect contribute to general psychopathology through distinct clinical consequences, independently of temperamental and characterological features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980786"}
{"pmid": "20980787", "title": "Morphogenetic targets and genetics of undescended testis.", "content": "Morphogenetic targets and genetics of undescended testis. Although important advances in testicular physiology have been achieved, the aetiology of human cryptorchidism remains mostly unknown. Next to sex steroidal signaling pathways, morphogenetic genes are specifically involved in the testicular descent via gubernacular development. Mutations in the human genes encoding insulin-like factor 3 (INSL3) and its Leu-rich repeat-containing G protein-coupled receptor 8 (LGR8), homeobox A10 (HOXA10), zinc finger 214 (ZNF214) and 215 (ZNF215) have occasionally been identified but do not seem to be a frequent cause of cryptorchidism. On the other hand, common polymorphisms in these genes have recently been investigated as contributing risk factors for idiopathic isolated (nonsyndromic) cryptorchidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980787"}
{"pmid": "20980788", "title": "An XY agonadal Oldenburg warmblood horse exhibiting a male phenotype.", "content": "An XY agonadal Oldenburg warmblood horse exhibiting a male phenotype. In a 1.5-year-old Oldenburg horse, a clitoris-like structure instead of a penis was identified in the prepuce. The external genital organs did not show any abnormalities at visual inspection except that exteriorization of the penis was not possible, not even under general anesthesia. The horse's owner observed a continuous dripping of urine and a tendency to mild colics beginning 2 weeks after birth. Testosterone concentration was 0.01 ng/ml and therefore under the threshold for geldings, and the horse did not respond to the application of gonadotropin-releasing hormone (GnRH). The inner genital consisted of a male urinary tract. Gonads and accessory male glands were missing. Residual structures of a female genital tract were not observed. Abnormalities of the mesentery could be found which might explain the recurrent colics of this horse. A cytogenetic examination revealed a 2n = 64,XY-karyotype and a positive result for the SRY-PCR. This is the first report on an agonadal horse with a male karyotype and a pseudohermaphrodite phenotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980788"}
{"pmid": "20980789", "title": "Feasibility and activity of sorafenib and sunitinib in advanced penile cancer: a preliminary report.", "content": "Feasibility and activity of sorafenib and sunitinib in advanced penile cancer: a preliminary report. We describe our experience with sorafenib and sunitinib in the treatment of chemotherapy-refractory advanced penile squamous cell carcinoma (SCC). Between May 2008 and June 2009, 6 advanced penile cancer patients were treated with sorafenib or sunitinib in our center. All of them had previously received at least two chemotherapy regimens. Tumor responses were evaluated by radiologic assessment and serum SCC antigen change. Immunohistochemical staining of CD34 and Ki-67 was performed in 3 paired tumor tissues before and after treatment. In the 6 patients, 1 partial response and 4 stable diseases were observed. Three patients showed pain response and had an improvement in quality of life. After molecular-targeted therapies, reduction in microvessel density and Ki-67 labeling index was observed in paired specimens. Serum SCC antigen levels were decreased in 5 patients after 1 week of medication. The patient who achieved partial response had an SCC antigen reduction of nearly 95% after treatment with sunitinib. Serious adverse events were fatal infection and rupture of the femoral vessel, which were unlikely related to the medication. The feasibility and activity of sorafenib and sunitinib in our series suggest that this approach may be a promising alternative in chemotherapy-refractory advanced penile SCC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980789"}
{"pmid": "20980790", "title": "Heat shock protein 90 regulates IκB kinase complex and NF-κB activation in angiotensin II-induced cardiac cell hypertrophy.", "content": "Heat shock protein 90 regulates IκB kinase complex and NF-κB activation in angiotensin II-induced cardiac cell hypertrophy. Heat shock protein 90 (HSP90), one of the most abundant proteins in the cardiac cells is essential for cell survival. Previous studies have shown that angiotensin II induces cardiac cell hypertrophy. However, the role of HSP90 in the angiotensin II-induced cardiac hypertrophy is unclear. In this study, we showed that HSP90 regulated angiotensin II-induced hypertrophy via maintenance of the IκB kinase (IKK) complex stability in cardiac cells. An HSP90 inhibitor, geldanamycin (GA), significantly suppressed angiotensin II-induced [³H]leucine incorporation and atrial natriuretic factor expression in cardiac cells. GA also inhibited the NF-κB activation induced by angiotensin II. Importantly, treatment with GA caused a degradation of IKKα/β; on the other hand, a proteasome-specific inhibitor restored the level of IKKα/β. We also found that GA prevented HSP90-IKKs complex induced by angiotensin II in cardiac cells. The small interfering RNA (siRNA)-mediated knockdown of HSP90 expression significantly inhibited angiotensin II-induced cell hypertrophy and NF-κB activation. These results suggest that angiotensin II-induced cardiac hypertrophy requires HSP90 that regulates the stability and complex of IKK.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980790"}
{"pmid": "20980792", "title": "Premature infants and vaccination.", "content": "Premature infants and vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980792"}
{"pmid": "20980791", "title": "Caring about rabies: a deadly, neglected disease.", "content": "Caring about rabies: a deadly, neglected disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980791"}
{"pmid": "20980793", "title": "Haemophilus influenzae type b conjugate vaccines: considerations for vaccination schedules and implications for developing countries.", "content": "Haemophilus influenzae type b conjugate vaccines: considerations for vaccination schedules and implications for developing countries. Prior to widespread vaccination, Haemophilus influenzae type b was a leading cause of severe childhood bacterial infection, including meningitis, worldwide. Over the last decade the world has taken great strides towards controlling Hib disease through routine use of conjugate vaccines in developed and developing countries. Currently there is no consensus on the appropriate schedule by which to use Hib vaccine. Vaccination schedules around the world vary greatly, particularly between high and low income countries. Questions remain as to the most effective and efficient schedule of primary doses, the need for a booster dose, and the implications of using combination vaccines. Here, we present a synthesis of data supporting various Hib vaccine schedules, with a focus on the implications for developing countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980793"}
{"pmid": "20980794", "title": "The global pertussis initiative: Meeting report from the Regional Latin America Meeting, Costa Rica, 5-6 December, 2008.", "content": "The global pertussis initiative: Meeting report from the Regional Latin America Meeting, Costa Rica, 5-6 December, 2008. Pertussis remains endemic across the world, with an estimated 279,000 deaths in 2002, the majority in infants under 1 year of age. Worldwide epidemiologic data indicates increasing infection rates in older children and adults, which act as a source of infection to young infants. The Global Pertussis Initiative (GPI) is an expert scientific forum, which has published consensus recommendations for the monitoring, prevention, and treatment of the disease. This paper reports the proceedings of a regional meeting, held in Costa Rica in December 2008. The meeting gathered information on regional epidemiological, diagnostic capabilities and the ability to introduce GPI recommended vaccine strategies in Latin America. The capacity of Latin American countries to conduct vaccination programs is high and there is considerable government support. Whole-cell pertussis vaccines are used across Latin America, which appear to be quite effective. A 4-dose schedule is typically used (2, 4, 6, and 18 months), and a booster given at 4 to 6 years of age, with coverage often above 90%, but with regions of low coverage due to political and geographical difficulties. Adequate surveillance is lacking in many countries, giving insufficient data to guide vaccination policy. Improvements are being made, with countries such as Costa Rica, Panama, and Argentina introducing polymerase chain reaction (PCR) diagnosis. Those countries that do not currently use a preschool booster should launch one. Implementing vaccination programs in adolescents and/or adults to reduce exposure to infants would be beneficial and possible in most countries, given their current infrastructure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980794"}
{"pmid": "20980795", "title": "Immunogenicity and safety of a novel AS03(A)-adjuvanted H1N1 2009 pandemic influenza vaccine in adults in Japan.", "content": "Immunogenicity and safety of a novel AS03(A)-adjuvanted H1N1 2009 pandemic influenza vaccine in adults in Japan. This study evaluated the immunogenicity and safety of a novel H1N1 2009 pandemic vaccine(A/California/7/2009) in Japanese adults. Following Dose 1, seroprotection rate (HI titre ≥1:40) was 95%, seroconversion rate was 94% and the geometric mean titre (GMT) was 230.3 (geometric mean fold rise [GMFR]: 26.3). Following Dose 2, seroprotection rate as well as seroconversion rate were 100%; HI antibody GMT rose to 485 (GMFR: 55.4). European and United States regulatory acceptance criteria for immunogenicity were met and exceeded following each dose of the vaccine. Solicited symptoms recorded during the 7-day post-vaccination follow-up period were of mild to moderate intensity (Grade 3: ≤4% of subjects). The most frequently reported solicited symptoms after both doses were pain at the injection site, fatigue and muscle ache. Unsolicited adverse events causally related to vaccination were reported in 18 subjects; none were of Grade 3 intensity. There were no serious adverse events. This open-label, single-group, multi-center Phase II study enrolled 100 healthy subjects aged 20-64 years(stratification [1:1] by age: 20-40 years and 41-64 years) to receive 21 days apart, two doses of a monovalent, split-virion AS03(A)-adjuvanted H1N1 2009 pandemic vaccine (3.75 μg hemagglutinin [HA]). Blood samples collected before vaccination and 21 days after each dose were analyzed using hemagglutination inhibition (HI) assay. A single dose of AS 03A-adjuvanted, 3.75 μg HA H1N1 2009 pandemic influenza vaccine was highly immunogenic in Japanese adults with a clinically acceptable safety profile, thereby making it a potential candidate for mitigating A/H1N1-associated morbidity and mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980795"}
{"pmid": "20980797", "title": "Evaluation of vaccination results in high-risk patients included in hepatitis B vaccination program.", "content": "Evaluation of vaccination results in high-risk patients included in hepatitis B vaccination program. Hepatitis B infection is one of the infectious diseases quite common in Turkey and around the world. Hepatitis B virus infection is a significant health problem which may cause chronic hepatitis, cirrhosis and hepatocellular carcinoma. With the introduction of Hepatitis B vaccine, a significant progress has been made in the prevention of HBV infections. The purpose of the study was to evaluate the characteristics of the individuals included in the risk group who admitted to our vaccination clinic, as well as their immune responses following the vaccination. Among the patients admitted to the vaccination clinic of our hospital between January 2003-December 2005 and that were included in the risk group (patients who have family members with chronic Hepatitis B infection, healthcare workers, hemodialysis patients etc.), those who were included in the vaccination program by examining the results of HBs Ag, anti-HBc and anti-HBs were evaluated in terms of their characteristics (age, gender, smoking etc.) and results of Anti-HBs score. A total of 958 people were included in the vaccination program. Upon evaluation in terms of risk factors, presence of patients with chronic hepatitis B infection in the family was found to be 80.6% (772/958), being healthcare worker was 9.2% (88/958), HCV positivity and chronic liver disease was 3.0% (29/958), being a hemodialysis patient was 2.8% (27/958), and being an oncology patient was 2.1% (20/958). Post-vaccination immune response could be evaluated in 69.8% (669/958) of patients and no responsiveness to vaccine was detected only in 8.1% (54/669) of them. Of the non-responders, 64.8% (35/54) were hemodialysis and oncology patients. Anti-HBs positivity rate following hepatitis B vaccination program was found compatible with the results of previous studies. With this vaccine of considerably high effectiveness, immunization of the entire community including primarily the risk groups should be targeted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980797"}
{"pmid": "20980798", "title": "Assessment of HPV vaccines: from the burden of disease to the health technology assessment approach.", "content": "Assessment of HPV vaccines: from the burden of disease to the health technology assessment approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980798"}
{"pmid": "20980796", "title": "Concomitant administration of zoster and pneumococcal vaccines in adults ≥60 years old.", "content": "Concomitant administration of zoster and pneumococcal vaccines in adults ≥60 years old. This study evaluated safety & immunogenicity of ZOSTAVAX® (zoster vaccine: ZV) administered concomitantly versus nonconcomitantly with PNEUMOVAX® 23 (pneumococcal vaccine: PPV23). This randomized, double-blind, placebo-controlled study enrolled 473 subjects ≥60 years old in 1:1 ratio to receive ZV & PPV23 concomitantly (Day 1) or nonconcomitantly (PPV23 Day 1, ZV Week 4). Blood samples obtained for pneumococcal polysaccharide (PnPs) antibody (Ab) testing by enzyme-linked immunosorbent assay (ELISA) and varicella-zoster virus (VZV) Ab testing by glycoprotein ELISA. Subjects followed for adverse experiences (AEs) for 28 days postvaccination. Mean baseline VZV geometric mean titers (GMT) in nonconcomitant group were lower than concomitant group. Four weeks postvaccination with ZV, VZV Ab response in concomitant group was not similar to nonconcomitant group; estimated VZV GMT ratio [concomitant/nonconcomitant] was 0.70 (95% CI, 0.61-0.80). VZV Ab response was acceptable in concomitant group; estimated geometric mean foldrise (GMFR) from baseline was 1.9 (95% CI, 1.7-2.1). PnPs serotype-specific Ab responses were similar in both groups. All 6 reported serious AEs were deemed not related to study vaccine. Postvaccination of ZV, incidence of injection-site AEs was similar in both groups; clinical AEs were numerically but not significantly higher in nonconcomitant group. In summary, VZV GMT Ab response induced by ZV administered concomitantly with PPV23 was inferior to that induced nonconcomitantly. These results indicate that, to avoid a potential decrease in ZV immunogenicity, ZV & PPV23 should not be given concomitantly. Concomitant administration did not affect response to PPV23 serotypes tested. When administered concomitantly, ZV & PPV23 vaccines were generally well tolerated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980796"}
{"pmid": "20980799", "title": "Anti-tau oligomers passive vaccination for the treatment of Alzheimer disease.", "content": "Anti-tau oligomers passive vaccination for the treatment of Alzheimer disease. The aggregation and accumulation of the microtubule-associated protein (Tau) is a pathological hallmark of Alzheimer's disease (AD) and many neurodegenerative diseases. Despite the poor correlation between neurofirillary tangles (NFTs) and disease progression, and evidence showing, that neuronal loss in AD actually precedes NFTs formation research until recently focused on them and other large meta-stable inclusions composed of aggregated hyperphosphorylated tau protein. Lately, the significance and toxicity of NFTs has been challenged and new aggregated tau entity has emerged as the true pathogenic species in tauopathies and a possible mediator of Aβ toxicity in AD. Tau intermediate aggregate (tau oligomers; aggregates of an intermediate that is between monomers and NFTs in size) can cause neurodegeneration and memory impairment in the absence of Aβ. This exciting body of evidence includes results from human brain samples, transgenic mouse and cell-based studies. Despite extensive efforts to develop a safe and efficacious vaccine for AD using Aβ peptide as an immunogen in active vaccination approaches or anti Aβ antibodies for passive vaccination, success has been modest. Nonetheless, these studies have produced a wealth of fundamental knowledge that has potential to application to the development of a tau-based immunotherapy. Herein, I discuss the evidence supporting the critical role of tau oligomers in AD, the potential and challenges for targeting them by immunotherapy as a novel approach for AD treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980799"}
{"pmid": "20980800", "title": "Simplified β-amyloid peptides for safer Alzheimer's vaccines development.", "content": "Simplified β-amyloid peptides for safer Alzheimer's vaccines development. Over the past few years, new ways of fighting Alzheimer's disease have emerged based on stimulating the immunitary defence system of the patients. To avoid toxicity and autoimmune response related to the Aβ[1-42] peptide immunotherapy, in the last decade a large number of works aimed at identifying new classes of safe Aβ derivatives by modifying the full length β-amyloid form. In strict agreement with the purposes of the sequence-simplification technology, Aβ[1-16], Aβ[13-28] and Aβ[25-42] fragments were selected in order to retain the major immunogenic sites of the Aβ[1-42] peptide, and corresponding simplified forms were designed and synthesized. All glycinated Aβ derivatives showed immunogenic and antigenic properties similar to the parent Aβ[1-42] peptide, and raised antibodies were all able to cross-recognize both Aβ[1-42] and Aβ[1-40] synthetic structures. All Aβ simplified forms showed reduced fibrillogenic and inflammatory properties. In particular, the Aβ[13-28]+G form failed to induce IFN-γ production thus suggesting that this molecule could represent a good candidate for potentially safer AD vaccine therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980800"}
{"pmid": "20980801", "title": "AFFITOME® technology in neurodegenerative diseases: the doubling advantage.", "content": "AFFITOME® technology in neurodegenerative diseases: the doubling advantage. Neurodegenerative diseases are still an area of unmet medical need. This is in contrast to our increasing knowledge on their pathology (e.g., Alzheimer's- (AD), Parkinson's (PD) disease). They are driven by the cerebral accumulation and aggregation of specific proteins (e.g., β-amyloid and hyperphosphorylated tau in the case of AD) in defined brain regions and, as a consequence, death of neurons. Accordingly, removal of given protein aggregates is expected to modify the course of the respective neurodegenerative disease. This has been convincingly demonstrated in animal models of human diseases. However, not every technology that can be used and proves successful in animal models can be translated to the human situation. As highlighted by recent progress in the field of AD research, specific immunotherapy is a viable option in this regard. Given the fact that the aggregates are composed of self-proteins, immunotherapeutic approaches have to consider the issue of potential autoimmunity. This is especially true in case of vaccines. An innovative solution to this problem is offered by the so called AFFITOME® technology, which relies on the use of \"doubles\" of native molecules, functionally mimotopes or AFFITOPES® if identified by AFFiRiS, as the antigenic vaccine component.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980801"}
{"pmid": "20980802", "title": "Effectiveness of Lanzhou lamb rotavirus vaccine against hospitalized gastroenteritis: further analysis and update.", "content": "Effectiveness of Lanzhou lamb rotavirus vaccine against hospitalized gastroenteritis: further analysis and update.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980802"}
{"pmid": "20980804", "title": "Cell cycle control of cell death in yeast.", "content": "Cell cycle control of cell death in yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980804"}
{"pmid": "20980803", "title": "Differential regulation of MMP7 in colon cancer cells resistant and sensitive to oxaliplatin-induced cell death.", "content": "Differential regulation of MMP7 in colon cancer cells resistant and sensitive to oxaliplatin-induced cell death. We have previously shown that metalloproteinase 7 (MMP7) expression is increased during the acquisition of resistance to oxaliplatin in colon cancer cells. Now we have analyzed the implication of β-catenin and EGFR pathways in the up-regulation of MMP7 in the oxaliplatin-resistant human colon cancer cell lines RHT29 and RHCT116 p53-/-, derived from the HT29 and HCT116 p53-/- cells, respectively. Oxaliplatin treatment increased EGFR expression and induced its activation in all the cell lines. However, β-catenin mRNA was only upregulated in the HT29 and RHT29 cells, with a marked increase in the nuclear/cytoplasmic β-catenin protein ratio in the oxaliplatin-resistant RHT29 cells. To determine the contribution of β-catenin and EGFR to the expression of MMP7 we performed siRNA experiments. β-catenin abrogation only prevented the induction of MMP7 by oxaliplatin in HT29 and RHT29 cells. Accordingly, viability of oxaliplatin-treated RHT29 cells under β-catenin silencing was decreased. On the other hand, EGFR siRNA induced contradictory effects, decreasing PEA3 and MMP7 expression in control and oxaliplatin-treated RHCT116 p53-/- cells but increasing basal- and oxaliplatin-induced PEA3 and MMP7 in the HT29 and RHT29 cells. Oxaliplatin-induced MMP7 up-regulation is differentially achieved in colon cancer cell lines, as a result of EGFR and β-catenin cross-talk on MMP7 gene transcription. Taken together, our results point out the disparity of effects that β-catenin and EGFR blocking therapeutic strategies may exert on MMP7 expression depending on the cellular context and remark the importance of a better knowledge of MMP7 regulation to improve chemotherapy effectiveness in colon cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980803"}
{"pmid": "20980805", "title": "p53 and senescence: A little goes a long way.", "content": "p53 and senescence: A little goes a long way.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980805"}
{"pmid": "20980806", "title": "New insights into 5q- syndrome as a ribosomopathy.", "content": "New insights into 5q- syndrome as a ribosomopathy. Myelodysplastic Syndromes (MDS) are a heterogeneous group of acquired clonal bone marrow disorders, characterised by ineffective hematopoiesis. The mechanisms underlying many of these blood disorders have remained elusive due to the difficulty in pinpointing specific gene mutations or haplo-insufficencies, which can occur within large deleted regions. However, there is an increasing interest in the classification of some of these diseases as ribosomopathies. Indeed, studies have implicated Ribosomal Protein (RP) S14 as a strong candidate for haploinsufficiency in 5q- syndrome, a particular form of MDS. Recently, two novel mouse models have provided evidence for the involvement of both RPS14 and the p53 pathway, and specific miRNAs in 5q- syndrome. In this review we will discuss: 5q- syndrome mouse models, the possible mechanisms underlying this blood disorder with respect to the candidate genes and comparisons with other ribosomopathies and the involvement of the p53 pathway in these diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980806"}
{"pmid": "20980807", "title": "Aven-uing between nuclear export and cell cycle arrest.", "content": "Aven-uing between nuclear export and cell cycle arrest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980807"}
{"pmid": "20980808", "title": "Rarity of AKT1 and AKT3 E17K mutations in squamous cell carcinoma of lung.", "content": "Rarity of AKT1 and AKT3 E17K mutations in squamous cell carcinoma of lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980808"}
{"pmid": "20980809", "title": "Adrenal cortex and micro-RNAs: An update.", "content": "Adrenal cortex and micro-RNAs: An update.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980809"}
{"pmid": "20980810", "title": "Toward the mechanisms preventing merotelic kinetochore-microtubule attachments.", "content": "Toward the mechanisms preventing merotelic kinetochore-microtubule attachments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980810"}
{"pmid": "20980811", "title": "RhoBTB2 (DBC2) comes of age as a multifunctional tumor suppressor.", "content": "RhoBTB2 (DBC2) comes of age as a multifunctional tumor suppressor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980811"}
{"pmid": "20980812", "title": "Histone genes, DNA replication, apoptosis and aging: What are the connections?", "content": "Histone genes, DNA replication, apoptosis and aging: What are the connections?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980812"}
{"pmid": "20980813", "title": "Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase.", "content": "Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase. Autophagy mediates the degradation of cytoplasmic components in eukaryotic cells and plays a key role in immunity. The mechanism of autophagosome formation is not clear. Here we examined two potential membrane sources for antibacterial autophagy: the ER and mitochondria. DFCP1, a marker of specialized ER domains known as 'omegasomes,' associated with Salmonella-containing autophagosomes via its PtdIns(3)P and ER-binding domains, while a mitochondrial marker (cytochrome b5-GFP) did not. Rab1 also localized to autophagosomes, and its activity was required for autophagosome formation, clearance of protein aggregates and peroxisomes, and autophagy of Salmonella. Overexpression of Rab1 enhanced antibacterial autophagy. The role of Rab1 in antibacterial autophagy was independent of its role in ER-to-Golgi transport. Our data suggest that antibacterial autophagy occurs at omegasomes and reveal that the Rab1 GTPase plays a crucial role in mammalian autophagy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980813"}
{"pmid": "20980814", "title": "A quantitative assay for the monitoring of autophagosome accumulation in different phases of the cell cycle.", "content": "A quantitative assay for the monitoring of autophagosome accumulation in different phases of the cell cycle. Macroautophagy is a process accompanied by the formation of double-membrane vesicles known as autophagosomes. Although in recently published reviews various methods for the detection of autophagosomes were described, a reliable technique for the automated quantitative evaluation of autophagosome accumulation is still lacking. Here we developed a new assay which is based on the fact that the number of autophagosomes is correlated with the amount of the LC3-II protein, which is specifically associated with autophagosomal membranes. Monitoring of autophagosome: accumulation was performed by extracting the membrane-unbound LC3-I form of the protein from cells, followed by flow cytometric detection of the autophagosomal membrane-associated fraction of LC3-II. This assay could be used for monitoring autophagosomes by flow cytometry utilizing immunostaining with the antibody against the LC3 protein. It is also suitable for analysis of: cells expressing GFP-LC3. We showed that co-staining with propidium iodide allows detection of basal level of autophagosomes in different phases of the cell cycle. Autophagy activators, such as: rapamycin or cell starvation, were able to induce accumulation of autophagosomes in G0/G1, S and G2/M phases. Thus, utilization of this assay simplifies monitoring of autophagosome accumulation induced by different activators or inhibitors of macroautophagy and it is suggested as being useful in the detection of autophagosomes in different phases of the cell cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980814"}
{"pmid": "20980816", "title": "PUMA-mediated tumor suppression: A tale of two stories.", "content": "PUMA-mediated tumor suppression: A tale of two stories. Several recent studies provided evidence that PUMA, a pro-apoptotic member of the BH3-only protein subgroup of the Bcl-2 family, is critical for restricting survival and recovery of different cell types, including those of the hematopoietic system, after γ-irradiation (IR)-triggered DNA damage. According to its pro-apoptotic function downstream of p53, PUMA is considered to act as a tumor suppressor. While this expectation was met in a model of oncogene-driven lymphomagenesis or carcinogen-driven tumor formation in the gut, studies on IR-driven tumor formation revealed surprising new insights into the role of p53-triggered and PUMA-mediated apoptosis in tumorigenesis and stem cell homeostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980816"}
{"pmid": "20980815", "title": "PIN it on auxin: the role of PIN1 and PAT in tomato development.", "content": "PIN it on auxin: the role of PIN1 and PAT in tomato development. The growth and development of plants is regulated by several external and internal factors including auxin. Its distribution regulates several developmental processes in plants. Auxin molecules function as mobile signals and are involved in the spatial and temporal coordination of plant morphogenesis and in plant responses to their environment. The intercellular transport of auxin is facilitated by transport proteins and the disruption of polar auxin flow results in various developmental abnormalities. In this review, we discuss the developmental and physiological significance of over-accumulation of PIN1 auxin transport facilitator protein in tomato as seen in the enhanced polar auxin transport pct1-2 mutant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980815"}
{"pmid": "20980817", "title": "Chromosomes kiss and tell: Long-range chromosome contacts modulate replication termination.", "content": "Chromosomes kiss and tell: Long-range chromosome contacts modulate replication termination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980817"}
{"pmid": "20980818", "title": "Repeat-element driven activation of proto-oncogenes in human malignancies.", "content": "Repeat-element driven activation of proto-oncogenes in human malignancies. Recent data demonstrated that the aberrant activity of endogenous repetitive elements of the DNA in humans can drive the expression of proto-oncogenes. This article summarizes these results and gives an outlook on the impact of these findings on the pathogenesis and therapy of human cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980818"}
{"pmid": "20980819", "title": "Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae.", "content": "Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. DNA replication in eukaryotic cells is tightly regulated to ensure faithful inheritance of the genetic material. While the replicators, replication origins and many replication-initiation proteins in Saccharomyces cerevisiae have been identified and extensively studied, the detailed mechanism that controls the initiation of DNA replication is still not well understood. It is likely that some factors involved in or regulating the initiation of DNA replication have not been discovered. To identify novel DNA replication-initiation proteins and their regulators, we developed a sensitive and comprehensive phenotypic screen by combining several established genetic strategies including plasmid loss assays with plasmids containing a single versus multiple replication origins and colony color sectoring assays. We isolated dozen of mutants in previously known initiation proteins and identified several novel factors, including Ctf1p Ctf3p, Ctf4p, Ctf18p, Adk1p and Cdc60p, whose mutants lose plasmid containing a single replication origin at high rates but lose plasmid carrying multiple replication origins at lower rates. We also show that overexpression of replication initiation proteins causes synthetic dosage lethality or growth defects in ctf1 and ctf18 mutants and that Ctf1p and Ctf18p physically interact with ORC, Cdt1p and MCM proteins. Furthermore, depletion of both Ctf1p and Ctf18p prevents S phase entry, retards S phase progression, and reduces pre-RC formation during the M-to-G₁ transition. These data suggest that Ctf1p and Ctf18p together play important roles in regulating the initiation of DNA replication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980819"}
{"pmid": "20980820", "title": "Two types of autophagy are better than one during hepatocyte oxidative stress.", "content": "Two types of autophagy are better than one during hepatocyte oxidative stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980820"}
{"pmid": "20980822", "title": "Cis-interactions between non-coding ribosomal spacers dependent on RNAP-II separate RNAP-I and RNAP-III transcription domains.", "content": "Cis-interactions between non-coding ribosomal spacers dependent on RNAP-II separate RNAP-I and RNAP-III transcription domains. Ribosome biogenesis requires transcription of structural RNAs. In budding yeast, ribosomal units contain both 35S and 5S RNA genes separated by intergenic spacer sequences (IGS) that are transcribed by RNAP-II. IGS transcripts cause instability by promoting unequal sister chromatid recombination between repeats and are thus rapidly degraded by the exosome. Whether RNAP-II within IGS regions plays any functional role is unknown. Here we demonstrate that the bulk of RNAP-II bound to IGS sites is blocked for elongation and hence remains in a poised or stalled configuration. We describe a novel role for these stalled RNAP-II complexes in the formation of cis-interactions between the IGS of rDNA. We show that this function separates 35S and 5S RNA genes into polymerase-specific chromatin loops and demonstrate that removal of stalled RNAP-II complexes causes displacement of RNAP-III from the 5S gene region and transcriptional downregulation of 5S rRNA by spreading of RNAP-I. We conclude that stalled RNAP-II plays an active role in the cis-organisation of ribosomal repeats providing domains of polymerase specificity in the nucleolar transcription environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980822"}
{"pmid": "20980823", "title": "A novel role for greatwall kinase in recovery from DNA damage.", "content": "A novel role for greatwall kinase in recovery from DNA damage. Activation of the DNA damage response (DDR) is critical for genomic integrity and tumor suppression. The occurrence of DNA damage quickly evokes the DDR through ATM/ATR-dependent signal transduction, which promotes DNA repair and activates the checkpoint to halt cell cycle progression. The \"turn off\" process of the DDR upon satisfaction of DNA repair, also known as \"checkpoint recovery\", involves deactivation of DDR elements, but the mechanism is poorly understood. Greatwall kinase (Gwl) has been identified as a key element in the G(2)/M transition and helps maintain M phase through inhibition of PP 2A/B55δ, the principal phosphatase for Cdk-phosphorylated substrates. Here we show that Gwl also promotes recovery from DNA damage and is itself directly inhibited by the DNA damage response (DDR). In Xenopus egg extracts, immunodepletion of Gwl increased the DDR to damaged DNA, whereas addition of wild type, but not kinase dead Gwl, inhibited the DDR. The removal of damaged DNA from egg extracts leads to recovery from checkpoint arrest and entry into mitosis, a process impaired by Gwl depletion and enhanced by Gwl overexpression. Moreover, activation of Cdk1 after the removal of damaged DNA is regulated by Gwl. Collectively, these results defines Gwl as a new regulator of the DDR, which plays an important role in recovery from DNA damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980823"}
{"pmid": "20980824", "title": "An in vitro chemoresponse assay defines a subset of colorectal and lung carcinomas responsive to cetuximab.", "content": "An in vitro chemoresponse assay defines a subset of colorectal and lung carcinomas responsive to cetuximab. Cetuximab is a chimeric monoclonal antibody for the epidermal growth factor receptor (EGFR) that may provide benefit to select cancer patients; however, identification of the characteristics of those patients who may benefit from its use is not complete. The ChemoFx® drug response marker (DRM) is an in vitro assay that can provide drug response data on tumor specimens before any patient treatment is initiated. We determined the feasibility of using the ChemoFx DRM to test tumor samples for sensitivity to cetuximab. We exposed four non-small cell lung carcinoma (NSCLC) cell lines (H358, H520, HCC827, and H1666) to cetuximab and determined their sensitivity using the ChemoFx DRM and, in parallel, EGFR status using immunocytochemistry, Western blotting, and In-Cell Western (TM) analysis. We used the ChemoFx DRM to determine cetuximab sensitivity of primary NSCLC and colorectal tumor samples. The ChemoFx DRM distinguished between cetuximab-sensitive and -resistant cell lines. Cetuximab sensitivity was not dependent on EGFR mutational status; H358 cells were non-responsive to cetuximab yet contain wild-type EGFR, whereas H1666 cells were intermediately responsive to cetuximab and contain wild-type EGFR. HCC827 (EGFR-mutant) cells were intermediately responsive and, as expected, H520 cells (EGFR-null) were non-responsive to cetuximab. ChemoFx-determined cetuximab sensitivity of primary NSCLC and colorectal tumor samples was 9.0% and 7.5%, respectively. Use of the ChemoFx DRM is feasible for determining cetuximab sensitivity. The ChemoFx-determined cetuximab responses of primary NSCLC and colorectal tumor specimens were similar to published response rates of patients to treatment with cetuximab monotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980824"}
{"pmid": "20980821", "title": "Rfc5p regulates alternate RFC complex functions in sister chromatid pairing reactions in budding yeast.", "content": "Rfc5p regulates alternate RFC complex functions in sister chromatid pairing reactions in budding yeast. Sister chromatid pairing reactions, termed cohesion establishment, occur during S-phase and appear to be regulated by Replication Factor C (RFC) complexes. For instance, RFCs that contain Ctf18p exhibit pro-establishment activities while those that contain Elg1p exhibit anti-establishment activities. It remains unknown whether Ctf18p-RFC and Elg1p-RFC functions are simply opposing or instead reveal complicated and non-parallel regulatory mechanisms. To better understand the nature of these novel pathways, we analyzed the small RFC subunit Rfc5p that is common to both Ctf18p-RFC and Elg1p-RFC. Despite this commonality, the data show that diminished Rfc5p function rescues ctf7/eco1 mutant cell phenotypes, revealing that Rfc5p promotes anti-establishment activities. This rescue is specific to establishment pathways in that rfc5-1 greatly accentuates growth defects when expressed in scc2 (deposition), mcd1/scc1 or smc3 (cohesion maintenance) mutated cells. Our results reveal for the first time a role for small RFC subunits in directing RFC complex functions-in this case towards anti-establishment pathways. We further report that Pds5p exhibits both establishment and anti-establishment functions in cohesion. This duality suggests that categorizations of establishment and anti-establishment activities require further examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980821"}
{"pmid": "20980826", "title": "Shifting senescence into quiescence by turning up p53.", "content": "Shifting senescence into quiescence by turning up p53.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980826"}
{"pmid": "20980825", "title": "Redundancy and variation in the ubiquitin-mediated proteolytic targeting of a transcription factor.", "content": "Redundancy and variation in the ubiquitin-mediated proteolytic targeting of a transcription factor. As central components of the intricate networks of eukaryotic gene regulation, transcription factors are frequent targets of ubiquitin-dependent proteolysis. A well-known example is the budding yeast MATα2 (α2) transcriptional repressor, which functions as a master regulator of cell-type determination. Degradation of α2 by the ubiquitin-proteasome system is necessary for a phenotypic switch from one cell type to another. A surprisingly complex set of ubiquitin-protein conjugation mechanisms are involved. One pathway utilizes an integral-membrane ubiquitin ligase (E3) that also functions in endoplasmic reticulum-associated degradation (ERAD). Recently, we showed that a second α2 ubiquitylation pathway uses a heterodimeric E3 that, while able to bind the ubiquitin-like protein SUMO, directly recognizes non-sumoylated α2. Other transcription factors are now also known to be ubiquitylated by multiple mechanisms; as many as a dozen E3s have been implicated in degradation of the human p53 tumor suppressor, for example. We discuss general issues of redundancy and mechanistic variation in protein modification by ubiquitin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980825"}
{"pmid": "20980827", "title": "The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts.", "content": "The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts. It is well established that there is a dynamic relationship between the expanding tumor and the host surrounding tissue. Cancer-associated fibroblasts (CAFs), the most common cellular population found in the tumor microenvironment, supporting tumor growth and dissemination. Here, we set out to determine the factors that may be involved in dramatic alteration of gene expression pattern in CAFs, focusing on microRNA and transcriptional regulators. We established matched pairs of human CAFs isolated from endometrial cancer and normal endometrial fibroblasts. MicroRNA and mRNA analyses identified differential expression of 11 microRNAs, with miR-31 being the most downregulated microRNA in CAFs (p = 0.007). We examined several putative miR-31 target genes identified by microarray analysis and demonstrated that miR-31 directly targets the homeobox gene SATB2, which is responsible for chromatin remodeling and regulation of gene expression, and was significantly elevated in CAFs. The functional relevance of miR-31 and SATB2 were tested in in vitro models of endometrial cancer. Overexpression of miR-31 significantly impaired the ability of CAFs to stimulate tumor cell migration and invasion, without affecting tumor cell proliferation. Genetic manipulation of SATB2 levels in normal fibroblasts or CAFs showed that, reciprocally to miR-31, SATB2 increased tumor cell migration and invasion, while knockdown of endogenous SATB2 in CAFs reversed this phenotype. Introduction of SATB2 into normal fibroblasts stimulated expression of a number of genes involved in cell invasion, migration and scattering. These findings provide new insights into tumor-stroma interaction and document that miR-31 and its target gene SATB2, are involved in regulation of tumor cell motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980827"}
{"pmid": "20980829", "title": "Autophagy in Gaucher disease due to saposin C deficiency.", "content": "Autophagy in Gaucher disease due to saposin C deficiency. Gaucher disease, due to a deficit of glucosylceramidase or, rarely, of its activator saposin C, is characterized by accumulation of glucosylceramide in the lysosomes of monocyte/macrophage lineage. In our study we demonstrate that saposin C deficiency due to mutations involving a cysteine residue results in increased autophagy. Autophagy was monitored by LC3 analysis and confirmed by electron microscopy; we observed a correlation among saposin C mutation, Gaucher phenotype and increased autophagy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980829"}
{"pmid": "20980828", "title": "Reduction of Pten dose leads to neoplastic development in multiple organs of Pten (shRNA) mice.", "content": "Reduction of Pten dose leads to neoplastic development in multiple organs of Pten (shRNA) mice. To address the impact of partial reduction of Pten on tumor initiation, we generated PtenshRNA mice, in which PTEN expression was reduced below normal levels in various tissues. PtenshRNA mice frequently developed lymphoid and prostatic hyperplasia, splenomegaly, and sebaceous adenomas. Our observations support the notion that partial reduction of the dose of Pten with shRNA is sufficient to induce neoplastic disease in multiple organ systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980828"}
{"pmid": "20980830", "title": "Regulation of autophagy by extracellular matrix glycoproteins in HeLa cells.", "content": "Regulation of autophagy by extracellular matrix glycoproteins in HeLa cells. Macroautophagy is a major lysosomal degradation pathway for cellular components in eukaryotic cells. Baseline macroautophagy is important for quality control of the cytoplasm in order to avoid the accumulation of cytotoxic products. Its stimulation by various stressful situations, including nutrient starvation, is important in maintaining cell survival. Here we demonstrate that macroautophagy is regulated differently depending on whether HeLa cells adhere to collagen I or collagen IV, proteins typical of connective tissue and basal membrane, respectively. We observed that the basal levels of macroautophagy were higher in cells plated on collagen IV than in cells plated on collagen I or on uncoated substrate. However, the stimulation of macroautophagy by nutrient starvation, as reflected by the buildup of autophagosomes and the increase in the autophagic flux, was higher in cells plated on collagen I than in cells plated on collagen IV. These contrasting results were not due to differences in the starvation-dependent inhibition of mTOR complex 1 signaling. Interestingly, cells plated on collagen IV formed numerous focal adhesions (FAs), whereas fewer FAs were observed in cells plated on the other substrates. This implies that focal adhesion kinase (FAK) was more robustly activated by collagen IV. Silencing the expression of FAK by siRNA in cells plated on collagen IV shifted the autophagic phenotype of these cells to an \"uncoated substrate autophagic phenotype\" under both basal and starvation-induced conditions. Moreover, cells plated on collagen IV were less dependent on autophagy to survive in the absence of nutrients. We conclude that extracellular matrix components can modulate macroautophagy and mitigate its role in cell survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980830"}
{"pmid": "20980832", "title": "E2F1 regulation by the APC/C.", "content": "E2F1 regulation by the APC/C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980832"}
{"pmid": "20980831", "title": "MAPK machinery in plants: recognition and response to different stresses through multiple signal transduction pathways.", "content": "MAPK machinery in plants: recognition and response to different stresses through multiple signal transduction pathways. The mitogen-activated protein kinase (MAPK) cascades play diverse roles in intra- and extra-cellular signaling in plants. MAP kinases are the component of kinase modules which transfer information from sensors to responses in eukaryotes including plants. They play a pivotal role in transduction of diverse extracellular stimuli such as biotic and abiotic stresses as well as a range of developmental responses including differentiation, proliferation and death. Several cascades are induced by different biotic and abiotic stress stimuli such as pathogen infections, heavy metal, wounding, high and low temperatures, high salinity, UV radiation, ozone, reactive oxygen species, drought and high or low osmolarity. MAPK signaling has been implicated in biotic stresses and has also been associated with hormonal responses. The cascade is regulated by various mechanisms, including not only transcriptional and translational regulation but through post-transcriptional regulation such as protein-protein interactions. Recent detailed analysis of certain specific MAP kinase pathways have revealed the specificity of the kinases in the cascade, signal transduction patterns, identity of pathway targets and the complexity of the cascade. The latest insights and finding are discussed in this paper in relation to the role of MAPK pathway modules in plant stress signaling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980831"}
{"pmid": "20980833", "title": "Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.", "content": "Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. In the present study, we report that compound C, an inhibitor of a key intracellular energy sensor AMP-activated protein kinase (AMPK), can induce autophagy in cancer cells. The induction of autophagy in U251 human glioma cell line was demonstrated by acridine orange staining of intracellular acidic vesicles, Beclin 1 induction, p62 decrease and conversion of LC3-I to autophagosome-associated LC3-II in the presence of proteolysis inhibitors. The presence of autophagosome-like vesicles was confirmed by transmission electron microscopy. Compound C-mediated inhibition of AMPK and raptor in U251 cells was associated with paradoxical decrease in phosphorylation of AMPK/raptor-repressed mTOR, a major negative regulator of autophagy, and its downstream target p70S6K. The phosphorylation of an mTOR activator Akt and the PI3K-activating kinase Src was also impaired in compound C-treated cells. The siRNA-mediated AMPK silencing did not reduce the activity of the Akt/mTOR/p70S6K pathway and AMPK activators metformin and AIC AR failed to block compound C-induced autophagy. Autophagy inhibitors bafilomycin and chloroquine significantly increased the cytotoxicity of compound C towards U251 cells, as confirmed by increase in lactate dehydrogenase release, DNA fragmentation and caspase-3 activation. Similar effects of compound C were also observed in C6 rat glioma, L929 mouse fibrosarcoma and B16 mouse melanoma cell lines. Since compound C has previously been reported to suppress AMPK-dependent autophagy in different cell types, our findings suggest that the effects of compound C on autophagy might be dose-, cell type- and/or context-dependent. By demonstrating the ability of compound C to induce autophagic response in cancer cells via AMPK inhibition-independent downregulation of Akt/mTOR pathway, our results warrant caution when using compound C to inhibit AMPK-dependent cellular responses, but also support further exploration of compound C and related molecules as potential anticancer agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980833"}
{"pmid": "20980834", "title": "Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin.", "content": "Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin. The efficiency of metazoan origins of DNA replication is known to be enhanced by histone acetylation near origins. Although this correlates with increased MCM recruitment, the mechanism by which such acetylation regulates MCM loading is unknown. We show here that Cdt1 induces large-scale chromatin decondensation that is required for MCM recruitment. This process occurs in G₁, is suppressed by Geminin, and requires HBO1 HAT activity and histone H4 modifications. HDAC11, which binds Cdt1 and replication origins during S-phase, potently inhibits Cdt1-induced chromatin unfolding and re-replication, suppresses MCM loading and binds Cdt1 more efficiently in the presence of Geminin. We also demonstrate that chromatin at endogenous origins is more accessible in G₁ relative to S-phase. These results provide evidence that histone acetylation promotes MCM loading via enhanced chromatin accessibility. This process is regulated positively by Cdt1 and HBO1 in G₁ and repressed by Geminin-HDAC11 association with Cdt1 in S-phase, and represents a novel form of replication licensing control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980834"}
{"pmid": "20980835", "title": "Identification of a high affinity TAG-72 binding peptide by phage display selection.", "content": "Identification of a high affinity TAG-72 binding peptide by phage display selection. Phage display was used to select novel peptides that specifically bind the TAG-72 antigen and with properties suitable for imaging TAG-72 positive cancers. After three rounds of selection against TAG-72 and using two different elution conditions including a long elution, the consensus sequences FRERCDKHPQKCTKFL and DPRHCQKRVLPCPAWL were expressed on phages G3-15 and T3-15 respectively. ELISA, fluorescence-activated cell sorting analysis and fluorescence microscopy provided evidence that both phages specifically bound TAG-72 in vitro. Both peptides are stable in 37oC serum. By a cell binding competition assay, the IC50 for T3-15 was measured as 0.29 nM and therefore 36-fold higher affinity than G3-15 at 10.32 nM. The biodistribution in mice carrying LS-174T tumors in one thigh were similar for both 99mTc-peptides at 30 min, but at 90 min the 99mTc-T3-15 peptide accumulated almost three times higher in the tumor. The SPECT/CT images were consistent with the biodistribution results. The f88-4/Cys6 phage library and two different elution conditions were used to identify two new higher affinity binding peptides for the TAG-72 antigen. One, was a single brief elution with pH 2.2 glycine buffer, and the second began with the glycine elution but was followed with a longer elution with Tris buffered saline (TBS) at pH 7.4. The phages that bound TAG-72 were evaluated by fluorescence-activated cell sorting analysis using TAG-72 positive LS-174T cells and confirmed by immunofluorescence imaging. The consensus peptides displayed on the selected phages were synthesized and conjugated with NHS-MAG3 for radiolabeling with 99mTc. The IC50 for TAG-72 binding was evaluated by cell binding competition in vitro while binding affinity was evaluated in vivo by necropsy and SPECT/CT imaging in a tumor mouse model. We have identified a peptide with a sub nanomolar inhibition constant for the TAG-72 antigen that may have application in cancer imaging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980835"}
{"pmid": "20980838", "title": "InhibitING entry into S phase and cell cycle progression.", "content": "InhibitING entry into S phase and cell cycle progression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980838"}
{"pmid": "20980837", "title": "Laminin regulates PI3K basal localization and activation to sustain STAT5 activation.", "content": "Laminin regulates PI3K basal localization and activation to sustain STAT5 activation. Extracellular matrix (ECM) is a key regulator of tissue morphogenesis and functional differentiation in the mammary gland. We showed recently that laminin-111 (LN1) together with prolactin induces β-casein expression in mammary epithelial cells (MECs) by sustaining STAT5 activation. Others have shown that Rac1 is required for integrin-mediated STAT5 activation, but molecules upstream of Rac1 remain to be elucidated. Here, we show that exposure to three-dimensional (3D) laminin-rich ECM (LrECM) gels changes the localization of phosphoinositide 3-kinase (PI3K) in MECs from diffuse to basal accompanied with the activation of PI3K-Rac1 signaling pathway. We show by co-immunoprecipitation that Rac1 associates with STAT5, and that LrECM treatment enhances this interaction. Blocking PI3K with LY294002 inhibits LrECM-dependent Rac1 activation, attenuates sustained STAT5 phosphorylation and blocks β-casein gene transcription. These results indicate that PI3K is a key mediator of the LN1-induced signaling cascade which controls the activity of transcription factors essential for tissue-specific gene expression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980837"}
{"pmid": "20980839", "title": "Important proposals for education-service exchange programs.", "content": "Important proposals for education-service exchange programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980839"}
{"pmid": "20980836", "title": "Helicase-inactivating mutations as a basis for dominant negative  phenotypes.", "content": "Helicase-inactivating mutations as a basis for dominant negative  phenotypes. There is ample evidence from studies of both unicellular and multicellular organisms that helicase-inactivating mutations lead to cellular dysfunction and disease phenotypes. In this review, we will discuss the mechanisms underlying the basis for abnormal phenotypes linked to mutations in genes encoding DNA helicases. Recent evidence demonstrates that a clinically relevant patient missense mutation in Fanconi Anemia Complementation Group J exerts detrimental effects on the biochemical activities of the FANCJ helicase, and these molecular defects are responsible for aberrant genomic stability and a poor DNA damage response. The ability of FANCJ to use the energy from ATP hydrolysis to produce the force required to unwind duplex or G-quadruplex DNA structures or destabilize protein bound to DNA is required for its DNA repair functions in vivo. Strikingly, helicase-inactivating mutations can exert a spectrum of dominant negative phenotypes, indicating that expression of the mutant helicase protein potentially interferes with normal DNA metabolism and has an effect on basic cellular processes such as DNA replication, the DNA damage response and protein trafficking. This review emphasizes that future studies of clinically relevant mutations in helicase genes will be important to understand the molecular pathologies of the associated diseases and their impact on heterozygote carriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980836"}
{"pmid": "20980841", "title": "Would a Flexner Report today focus only on graduate medical education?", "content": "Would a Flexner Report today focus only on graduate medical education?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980841"}
{"pmid": "20980842", "title": "Would a Flexner Report today focus only on graduate medical education?", "content": "Would a Flexner Report today focus only on graduate medical education?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980842"}
{"pmid": "20980844", "title": "The important role of medical licensure in the United States.", "content": "The important role of medical licensure in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980844"}
{"pmid": "20980846", "title": "Team-based learning: it's here and it WORKS!", "content": "Team-based learning: it's here and it WORKS!", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980846"}
{"pmid": "20980847", "title": "Education-for-service is not enough to meet our workforce needs.", "content": "Education-for-service is not enough to meet our workforce needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980847"}
{"pmid": "20980848", "title": "Commentary: A delicate balance: weighing the effects of conflict-of-interest rules on intramural research at the National Institutes of Health.", "content": "Commentary: A delicate balance: weighing the effects of conflict-of-interest rules on intramural research at the National Institutes of Health. In 2005, in response to increasing public concerns about potential conflicts of interest in biomedical research, the Department of Health and Human Services (DHHS) tightened its ethics rules to prohibit National Institutes of Health (NIH) employees from receiving consulting fees from \"significantly affected organizations.\" In response, NIH took steps to implement these regulations and ensure that relationships between intramural NIH researchers and industry could proceed without threatening the integrity of federally funded research. Examples of these steps include creating an ethics advisory committee to review outside activities of NIH scientists and subjecting its researchers to special scrutiny to eliminate any perception of personal profit or conflict of interest. In the authors' experiences, interactions between NIH scientists and industry have continued relatively unaffected by these regulations. The continuing success of the technology transfer program at NIH and the number and types of cooperative research and development agreements with industry are good measures of the extent of productive interactions with industry since the implementation of the 2005 ethics rules. Although recruitment of outstanding scientists to the intramural program has continued, these regulations also have challenged NIH's ability to attract and retain some of the most qualified scientists, who fear they may miss certain opportunities because of the tighter regulations. As DHHS revises the regulations governing oversight of financial conflicts of interest in the extramural community, the authors recognize that the NIH intramural experience may provide valuable lessons about developing and implementing the next generation of financial conflict-of-interest rules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980848"}
{"pmid": "20980849", "title": "Commentary: Taking back Year 4: a call to action.", "content": "Commentary: Taking back Year 4: a call to action. In this issue of Academic Medicine, Walling and Merando's literature review on the senior-year curriculum finds a broad consensus that this final year underperforms educationally at many U.S. medical schools, but little agreement on how to improve it. The review challenges us to consider how best to develop this key piece of educational real estate, which is too often frittered away on auditions, interview odysseys, and electives of uncertain educational value. In this commentary, the author approaches this education question from an unorthodox viewpoint, the delivery system and medical workforce perspectives. He proposes taking back major portions of Year 4 from elective clerkships and investing the time in required course work to prepare graduates to practice and lead in a redesigned 21st-century health system, providing superior access and outcomes at sustainable costs. The recommendations draw inspiration from the Institute of Medicine's \"Chasm\" reports, specifically echoing its 2003 Health Professions Education report that identified five new competencies deemed essential for all 21st-century health professionals. Finally, the author disputes the view that delivery system overhaul lies beyond the purview of educators, pointing to the historical precedent of the greatest medical paradigm shift of all time, the closure of the proprietary medical schools a century ago triggered by Flexner's report. The author closes by calling medical educators to action, to prepare the next generation of physicians to radically redesign health care and lead us out of the present crisis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980849"}
{"pmid": "20980850", "title": "Commentary: Are we ready to embrace the rest of the Flexner Report?", "content": "Commentary: Are we ready to embrace the rest of the Flexner Report? At the start of the 20th century, Abraham Flexner proposed a number of reforms for medical education in his seminal 1910 report, Medical Education in the United States and Canada. His recommendations were wide ranging, including a strong scientific basis, use of pedagogical methods, and faculty whose principal role is that of educator. Of these, reforms in science education for medicine received the widest attention and revolutionized physicians' intellectual foundations for medical practice. But what of Flexner's other suggested reforms, those skills needed to develop \"the educated man\" who can meet the \"greatly modified ethical responsibility\" of modern medical practice? As the 21st century begins, Flexner's ideas on these other subjects he considered critical for physician training are reappearing in the medical education literature. If history is a guide, medical education could be on the cusp of another set of great advances by renewing interest in medical humanities, reevaluating the makeup of medical school teaching faculty, and seeking innovations in pedagogy to facilitate active and integrated learning. The time is ripe to embrace the rest of the Flexner Report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980850"}
{"pmid": "20980851", "title": "Commentary: Flexner and Dutch medical education: a misinterpretation?", "content": "Commentary: Flexner and Dutch medical education: a misinterpretation? Abraham Flexner's 1910 report, Medical Education in the United States and Canada, was hardly noticed in the Netherlands, and though his 1925 book, Medical Education: A Comparative Study, was extensively discussed in the Dutch Medical Journal, it did not and could not affect medical education in the Netherlands. Until the 1970s, the medical curriculum in the Netherlands consisted of four phases: the propaedeutic year (premedical sciences), two preclinical years, two theoretical clinical years, and one-and-a-half to two years of clerkships. When in the 1970s interest in curriculum innovation arose in the Netherlands, it was based on developments in North America that challenged \"Flexnerian\" norms in medical education. As hardly anyone in the Netherlands cared to study Flexner's work closely, his name became synonymous with the conventional curriculum just as it had in North America. However, the Dutch conventional curriculum was quite different from the American conventional curriculum, so attributing its origins to Flexner's work was a serious misrepresentation. In this commentary, the author clarifies common misconceptions about the history of Dutch medical education and argues that the curriculum as Flexner saw it differed considerably from the Dutch medical curriculum a century ago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980851"}
{"pmid": "20980852", "title": "No debt, better education, and better health care: what's not to like?", "content": "No debt, better education, and better health care: what's not to like?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980852"}
{"pmid": "20980853", "title": "The Kansas Medical Student Loan program: a successful tuition-service exchange model.", "content": "The Kansas Medical Student Loan program: a successful tuition-service exchange model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980853"}
{"pmid": "20980854", "title": "The University of Chicago REACH program: improving health, decreasing debt.", "content": "The University of Chicago REACH program: improving health, decreasing debt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980854"}
{"pmid": "20980856", "title": "Community partnerships: alternative means of financing medical school.", "content": "Community partnerships: alternative means of financing medical school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980856"}
{"pmid": "20980855", "title": "Service residencies: a new approach to the medical education-service exchange.", "content": "Service residencies: a new approach to the medical education-service exchange.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980855"}
{"pmid": "20980857", "title": "The \"Medical Marshall Plan\": rebuilding public trust in American medicine.", "content": "The \"Medical Marshall Plan\": rebuilding public trust in American medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980857"}
{"pmid": "20980858", "title": "Return-of-service programs: meeting community and student needs in an ethical manner.", "content": "Return-of-service programs: meeting community and student needs in an ethical manner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980858"}
{"pmid": "20980859", "title": "SERVICE: Selecting Educational Residencies with Value, Incentives, Cost, and Effectiveness.", "content": "SERVICE: Selecting Educational Residencies with Value, Incentives, Cost, and Effectiveness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980859"}
{"pmid": "20980860", "title": "The F. Edward Hébert School of Medicine model: tuition-free medical school in exchange for public service.", "content": "The F. Edward Hébert School of Medicine model: tuition-free medical school in exchange for public service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980860"}
{"pmid": "20980861", "title": "The Primary Care Med-ED Plan: reducing medical student indebtedness while expanding primary care.", "content": "The Primary Care Med-ED Plan: reducing medical student indebtedness while expanding primary care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980861"}
{"pmid": "20980862", "title": "Write.", "content": "Write.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980862"}
{"pmid": "20980863", "title": "Artist's statement: Transposition.", "content": "Artist's statement: Transposition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980863"}
{"pmid": "20980866", "title": "2010 Humanism in Medicine Essay Contest: second place: The white coat.", "content": "2010 Humanism in Medicine Essay Contest: second place: The white coat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980866"}
{"pmid": "20980865", "title": "Medicine and the arts. Portrait of Dr. Samuel D. Gross (The Gross Clinic) by Thomas Eakins. Commentary.", "content": "Medicine and the arts. Portrait of Dr. Samuel D. Gross (The Gross Clinic) by Thomas Eakins. Commentary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980865"}
{"pmid": "20980867", "title": "AM last page: The health reform law and academic medicine.", "content": "AM last page: The health reform law and academic medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980867"}
{"pmid": "20980868", "title": "Early initiation of antiretroviral therapy and associated reduction in mortality, morbidity and defaulting in a nurse-managed, community cohort in Lesotho.", "content": "Early initiation of antiretroviral therapy and associated reduction in mortality, morbidity and defaulting in a nurse-managed, community cohort in Lesotho. The latest WHO guidelines recommend initiating antiretroviral therapy (ART) at CD4 cell counts less than 350 cells/μl. However, donors and national governments are reluctant to support implementation owing to uncertainty regarding feasibility and relative benefit. Lesotho has supported earlier initiation since 2008. We assessed outcomes comparing early (CD4 cell counts >200 cells/μl) and late (CD4 cell counts ≤200 cells/μl) initiation. We describe survival probability among patients initiating ART at CD4 cell counts 200 or less and more than 200 cells/μl and assess associations between baseline CD4 cell counts and mortality, morbidity, loss to follow-up and hospitalization using Cox regression adjusting for confounders identified a priori. Our analysis included 1177 patients; median age was 38 years and the majority (67%) were women. Median time on ART for the overall cohort was 506 days (interquartile range 396-608). Five hundred and thirty eight patients initiated ART at a CD4 cell count 200 cells/μl or less (interquartile range 54-160) and 639 patients initiated at CD4 cell count more than 200 cells/μl (interquartile range 238-321). In multivariate analysis, we found that patients initiating at CD4 cell count more than 200 cells/μl were 68% less likely to die (adjusted hazard ratio 0.32, 95% confidence interval 0.20-0.50), and 39% less likely to be lost to follow-up (adjusted hazard ratio 0.61, 95% confidence interval 0.43-0.87). Initiating ART at CD4 cell count more than 200 cells/μl was also associated with a 27% reduction in the rate of incident morbidity (adjusted hazard ratio 0.73, 95% confidence interval 0.65-0.82) and a 63% decreased rate of hospitalization (adjusted hazard ratio 0.37, 95% confidence interval 0.19-0.73). Earlier initiation is feasible in a low resource, high HIV prevalence setting, and provides important benefits in terms of reduced mortality, morbidity, retention and hospitalization. Donors should fully support the implementation of the latest WHO recommendations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980868"}
{"pmid": "20980869", "title": "Antiretroviral treatment is a behavioural intervention: but why?", "content": "Antiretroviral treatment is a behavioural intervention: but why?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980869"}
{"pmid": "20980871", "title": "Raltegravir-induced cerebellar ataxia.", "content": "Raltegravir-induced cerebellar ataxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980871"}
{"pmid": "20980870", "title": "The role of the health system in HIV treatment-as-prevention.", "content": "The role of the health system in HIV treatment-as-prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980870"}
{"pmid": "20980872", "title": "HIV-positive child with epidermodysplasia verruciformis-like lesions and homozygous mutation in TMC6.", "content": "HIV-positive child with epidermodysplasia verruciformis-like lesions and homozygous mutation in TMC6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980872"}
{"pmid": "20980873", "title": "Seroreversion in vertically HIV-1-infected children treated early and efficiently: rule or exception?", "content": "Seroreversion in vertically HIV-1-infected children treated early and efficiently: rule or exception?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980873"}
{"pmid": "20980874", "title": "Families are veterans, too.", "content": "Families are veterans, too.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980874"}
{"pmid": "20980875", "title": "A failure to rescue ourselves.", "content": "A failure to rescue ourselves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980875"}
{"pmid": "20980876", "title": "Material safety data sheets.", "content": "Material safety data sheets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980876"}
{"pmid": "20980877", "title": "Serving the patient.", "content": "Serving the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980877"}
{"pmid": "20980879", "title": "Cover conundrum.", "content": "Cover conundrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980879"}
{"pmid": "20980878", "title": "Where does the waste go?", "content": "Where does the waste go?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980878"}
{"pmid": "20980880", "title": "Rectal cancer rates rising in patients under 40.", "content": "Rectal cancer rates rising in patients under 40.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980880"}
{"pmid": "20980881", "title": "Working conditions at magnet hospitals.", "content": "Working conditions at magnet hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980881"}
{"pmid": "20980882", "title": "Cutting the pediatric insulin error rate.", "content": "Cutting the pediatric insulin error rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980882"}
{"pmid": "20980887", "title": "Calcium supplements may increase heart disease risk.", "content": "Calcium supplements may increase heart disease risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980887"}
{"pmid": "20980895", "title": "Managing dysphagia through diet modifications.", "content": "Managing dysphagia through diet modifications. Dysphagia can lead to malnutrition, dehydration, aspiration pneumonia, and even death. The condition has diverse causes and symptoms vary widely. Nurses are likely to encounter patients with dysphagia in various settings, including acute care medical units, rehabilitation centers, and skilled nursing facilities. Dietary modification--altering the consistency of foods and liquids--is a fundamental aspect of dysphagia management. This article describes normal and impaired swallowing, discusses several types and levels of dietary modification, and offers readers a concise list of nursing considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980895"}
{"pmid": "20980888", "title": "Chemotherapy drugs put health care workers at risk.", "content": "Chemotherapy drugs put health care workers at risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980888"}
{"pmid": "20980897", "title": "Caring for families with deployment stress.", "content": "Caring for families with deployment stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980897"}
{"pmid": "20980899", "title": "Evidence-based practice, step by step: Critical appraisal of the evidence: part III.", "content": "Evidence-based practice, step by step: Critical appraisal of the evidence: part III. This is the seventh article in a series from the Arizona State University College of Nursing and Health Innovation's Center for the Advancement of Evidence-Based Practice. Evidence-based practice (EBP) is a problem-solving approach to the delivery of health care that integrates the best evidence from studies and patient care data with clinician expertise and patient preferences and values. When delivered in a context of caring and in a supportive organizational culture, the highest quality of care and best patient outcomes can be achieved. The purpose of this series is to give nurses the knowledge and skills they need to implement EBP consistently, one step at a time. Articles will appear every two months to allow you time to incorporate information as you work toward implementing EBP at your institution. Also, we've scheduled \"Chat with the Authors\" calls every few months to provide a direct line to the experts to help you resolve questions. See details below.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980899"}
{"pmid": "20980900", "title": "Preparing for a year on the battlefield.", "content": "Preparing for a year on the battlefield.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980900"}
{"pmid": "20980906", "title": "RSS for the uninitiated.", "content": "RSS for the uninitiated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980906"}
{"pmid": "20980907", "title": "Safe intrahospital transport of non-ICU patients.", "content": "Safe intrahospital transport of non-ICU patients. The Pennsylvania Patient Safety Reporting System is a confidential, statewide Internet reporting system to which all Pennsylvania hospitals, outpatient-surgery facilities, and birthing centers, as well as some abortion facilities, must file information on medical errors.Safety Monitor is a column from Pennsylvania's Patient Safety Authority, the authority that informs nurses on issues that can affect patient safety and presents strategies they can easily integrate into practice. For more information on the authority, visit www.patientsafetyauthority.org. For the original article discussed in this column or for other articles on patient safety, click on \"Patient Safety Advisories\" and then \"Advisory Library\" in the left-hand navigation menu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980907"}
{"pmid": "20980908", "title": "Goodbye Cherry Ames.", "content": "Goodbye Cherry Ames.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980908"}
{"pmid": "20980909", "title": "The human carotid body: expression of oxygen sensing and signaling genes of relevance for anesthesia.", "content": "The human carotid body: expression of oxygen sensing and signaling genes of relevance for anesthesia. Hypoxia is a common cause of adverse events in the postoperative period, where respiratory depression due to residual effects of drugs used in anesthesia is an important underlying factor. General anesthetics and neuromuscular blocking agents reduce the human ventilatory response to hypoxia. Although the carotid body (CB) is the major oxygen sensor in humans, critical oxygen sensing and signaling pathways have been investigated only in animals so far. Thus, the aim of this study was to characterize the expression of key genes and localization of their products involved in the human oxygen sensing and signaling pathways with a focus on receptor systems and ion channels of relevance in anesthesia. Six CBs were removed unilaterally from patients undergoing radical neck dissection. The gene expression and cell-specific protein localization in the CBs were investigated with DNA microarrays, real-time polymerase chain reaction, and immunohistochemistry. We found gene expression of the oxygen-sensing pathway, heme oxygenase 2, and the K channels TASK (TWIK-related acid sensitive K channel)-1 and BK (large-conductance potassium channel). In addition, we show the expression of critical receptor subunits such as γ-aminobutyric acid A (α2, β3, and γ2), nicotinic acetylcholine receptors (α3, α7, and β2), purinoceptors (A2A and P2X2), and the dopamine D2 receptor. In unique samples of the human CB, we here demonstrate presence of critical proteins in the oxygen-sensing and signaling cascade. Our findings demonstrate similarities to, but also important differences from, established animal models. In addition, our work establishes an essential platform for studying the interaction between anesthetic drugs and human CB chemoreception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980909"}
{"pmid": "20980911", "title": "Retraction movement of the Frova airway intubation introducer to assist nasotracheal intubation in patients with limited mouth opening.", "content": "Retraction movement of the Frova airway intubation introducer to assist nasotracheal intubation in patients with limited mouth opening.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980911"}
{"pmid": "20980910", "title": "Neostigmine/glycopyrrolate administered after recovery from neuromuscular block increases upper airway collapsibility by decreasing genioglossus muscle activity in response to negative pharyngeal pressure.", "content": "Neostigmine/glycopyrrolate administered after recovery from neuromuscular block increases upper airway collapsibility by decreasing genioglossus muscle activity in response to negative pharyngeal pressure. Reversal of residual neuromuscular blockade by acetylcholinesterase inhibitors (e.g., neostigmine) improves respiratory function. However, neostigmine may also impair muscle strength. We hypothesized that neostigmine administered after recovery of the train-of-four (TOF) ratio impairs upper airway integrity and genioglossus muscle function. We measured, in 10 healthy male volunteers, epiglottic and nasal mask pressures, genioglossus electromyogram, air flow, respiratory timing, and changes in lung volume before, during (TOF ratio: 0.5), and after recovery of the TOF ratio to unity, and after administration of neostigmine 0.03 mg/kg IV (with glycopyrrolate 0.0075 mg/kg). Upper airway critical closing pressure (Pcrit) was calculated from flow-limited breaths during random pharyngeal negative pressure challenges. Pcrit increased significantly after administration of neostigmine/glycopyrrolate compared with both TOF recovery (mean ± SD, by 27 ± 21%; P = 0.02) and baseline (by 38 ± 17%; P = 0.002). In parallel, phasic genioglossus activity evoked by negative pharyngeal pressure decreased (by 37 ± 29%, P = 0.005) compared with recovery, almost to a level observed at a TOF ratio of 0.5. Lung volume, respiratory timing, tidal volume, and minute ventilation remained unchanged after neostigmine/glycopyrrolate injection. Neostigmine/glycopyrrolate, when administered after recovery from neuromuscular block, increases upper airway collapsibility and impairs genioglossus muscle activation in response to negative pharyngeal pressure. Reversal with acetylcholinesterase inhibitors may be undesirable in the absence of neuromuscular blockade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980910"}
{"pmid": "20980914", "title": "Identification of PD-1 as a unique marker for failing immune reconstitution in HIV-1-infected patients on treatment.", "content": "Identification of PD-1 as a unique marker for failing immune reconstitution in HIV-1-infected patients on treatment. PD-1 expression on T cells correlates with T-cell exhaustion and disease progression in HIV-infected patients. Previous studies have shown that combinational antiretroviral therapy induced viral suppression results in immune restoration and reduced PD-1 expression. However, a significant number of patients fail to restore CD4 T cells despite suppression of HIV replication below limit of quantification. In this study, we have analyzed PD-1 expression on CD4 and CD8 T cells in patients with poor immune reconstitution despite successful highly active antiretroviral therapy. We found that T cells of such patients express significantly higher levels of PD-1 than patients who had normal recovery of CD4 cells after treatment. In contrast, failing immune reconstitution was not associated with the expression of activation markers, indicating that PD-1 is a unique marker for failing immune reconstitution despite viral suppression. Furthermore, we show that T cells from patients with poor immune recovery differ from T cells of elderly in respect of their marker profile. PD-1 expression negatively correlated with individual CD4 cell counts, and PD-1 expressing T cells were more prone to programmed death ligand-mediated inhibition of T-cell proliferation, indicating that PD-1-mediated T-cell suppression may have a role in impaired immune reconstitution in HIV patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980914"}
{"pmid": "20980916", "title": "Structural, functional, and molecular alterations produced by aldosterone plus salt in rat heart: association with enhanced serum and glucocorticoid-regulated kinase-1 expression.", "content": "Structural, functional, and molecular alterations produced by aldosterone plus salt in rat heart: association with enhanced serum and glucocorticoid-regulated kinase-1 expression. We aimed to evaluate the structural, functional, inflammatory, and oxidative alterations, as well as serum and glucocorticoid-regulated kinase-1 (SGK-1) expression, produced in rat heart by aldosterone + salt administration. Fibrosis mediators such as connective tissue growth factor, matrix metalloproteinase 2, and tissue inhibitor of metalloproteinases 2 were also evaluated. Treatment with spironolactone was evaluated to prove mineralocorticoid mediation. Male Wistar rats received aldosterone (1 mg[middle dot]kg-1[middle dot]d-1) + 1% NaCl for 3 weeks. Half of the animals were treated with spironolactone (200 mg[middle dot]kg-1[middle dot]d-1). Systolic and diastolic blood pressures, left ventricle (LV) systolic pressure, and LV end-diastolic pressure were elevated (P < 0.05) in aldosterone + salt-treated rats. In aldosterone + salt-treated rats, -dP/dt decreased (P < 0.05), but +dP/dt was similar in all groups. Spironolactone normalized (P < 0.05) systolic blood pressure, diastolic blood pressure, LV systolic pressure, LV end-diastolic pressure, and -dP/dt. Relative heart weight, collagen content, messenger RNA expression of transforming growth factor beta, connective tissue growth factor, matrix metalloproteinase 2, tissue inhibitor of metalloproteinases 2, tumor necrosis factor alpha, interleukin-1[beta], p22phox, endothelial nitric oxide synhtase, and SGK-1 were increased (P < 0.05) in aldosterone + salt-treated rats, being reduced by spironolactone (P < 0.05). SGK-1 might be a key mediator in the structural, functional, and molecular cardiac alterations induced by aldosterone + salt in rats. All the observed changes and mediators are related with the activation of mineralocorticoid receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980916"}
{"pmid": "20980918", "title": "Intracerebroventricular leptin administration differentially alters cardiac energy metabolism in mice fed a low-fat and high-fat diet.", "content": "Intracerebroventricular leptin administration differentially alters cardiac energy metabolism in mice fed a low-fat and high-fat diet. Leptin directly acts on peripheral tissues and alters energy metabolism in obese mice. It also has acute beneficial effects on these tissues via its hypothalamic action. However, it is not clear what effect chronic intracerebroventrical (ICV) leptin administration has on cardiac energy metabolism. We examined the effects of chronic ICV leptin on glucose and fatty acid metabolism in isolated working hearts from high-fat-fed and low-fat-fed mice. Mice were fed a high-fat (60% calories from fat) or low-fat (10% calories from fat) diet for 8 weeks before ICV leptin (5 [mu]g/d) for 7 days. In low-fat-fed mice, leptin increased glucose oxidation rates in isolated working hearts when compared with control [203 +/- 21 vs. 793 +/- 93 nmol[middle dot](g dry weight)-1[middle dot]min-1]. In high-fat-fed mice leptin inhibited fatty acid oxidation [476 +/- 73 vs. 251 +/- 38 nmol[middle dot](g[middle dot]dry[middle dot]wt)-1[middle dot]min-1]. The increase in glucose oxidation in low-fat-fed mice was accompanied by increased pyruvate dehydrogenase activity. In high-fat-fed mice, leptin increased cardiac malonyl coenzyme A levels, secondary to a decrease in malonyl coenzyme A decarboxylase expression. These results suggest that ICV leptin alters cardiac energy metabolism opposite to its peripheral effects and that these effects differ depending on energy substrate supply to the mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980918"}
{"pmid": "20980913", "title": "HIV-related stigma, social norms, and HIV testing in Soweto and Vulindlela, South Africa: National Institutes of Mental Health Project Accept (HPTN 043).", "content": "HIV-related stigma, social norms, and HIV testing in Soweto and Vulindlela, South Africa: National Institutes of Mental Health Project Accept (HPTN 043). HIV testing is necessary to curb the increasing epidemic. However, HIV-related stigma and perceptions of low likelihood of societal HIV testing may reduce testing rates. This study aimed to explore this association in South Africa, where HIV rates are extraordinarily high. Data were taken from the Soweto and Vulindlela, South African sites of Project Accept, a multinational HIV prevention trial. Self-reported HIV testing, stigma, and social norms items were used to study the relationship between HIV testing, stigma, and perceptions about societal testing rates. The stigma items were broken into 3 factors: negative attitudes, negative perceptions about people living with HIV, and perceptions of fair treatment for people living with HIV (equity). Results from a univariate logistic regression suggest that history of HIV testing was associated with decreased negative attitudes about people living with HIV/AIDS, increased perceptions that people living with HIV/AIDS experience discrimination, and increased perceptions that people with HIV should be treated equitably. Results from a multivariate logistic regression confirm these effects and suggest that these differences vary according to sex and age. Compared with people who had never tested for HIV, those who had previously tested were more likely to believe that the majority of people have tested for HIV. Data suggest that interventions designed to increase HIV testing in South Africa should address stigma and perceptions of societal testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980913"}
{"pmid": "20980919", "title": "Hemodynamic actions of corticotropin-releasing hormone and proopiomelanocortin derivatives in septic patients.", "content": "Hemodynamic actions of corticotropin-releasing hormone and proopiomelanocortin derivatives in septic patients. Proopiomelanocortin (POMC) derivatives and mRNA of POMC have been detected in cardiomyocytes and vascular smooth muscle cells. Increased plasma levels of POMC derivatives have been found in septic patients during cardiovascular deregulation; therefore, we evaluated whether corticotroph-type (ACTH, β-endorphin, β-lipotropin) or melanotroph-type (α-melanocyte-stimulating hormone and N-acetyl-β-END) POMC derivatives have influences on patients' hemodynamics during sepsis. Seventeen septic patients were monitored by pulmonary artery catheter and corticotropin-releasing hormone (CRH) tests were performed by intravenous administration of 100 μg CRH. Before, 15, 30, 45, and 60 minutes after CRH administration, hemodynamic variables were measured, and plasma concentrations of POMC derivatives were determined. After CRH administration, heart rate, cardiac index, and stroke index increased, and the systemic vascular resistance index decreased; moreover, a correlation between ACTH concentration and stroke index as well as an inverse correlation between (α-melanocyte-stimulating hormone concentration and systemic vascular resistance index was observed. CRH and ACTH may have opposite effects on the blood pressure (mean arterial pressure). Immediately after CRH injection mean arterial pressure decreased. ACTH (in contrast to β-endorphin or β-lipotropin), released into the cardiovascular compartment 15 minutes after CRH injection, might have raised mean arterial pressure as compatible with the correlation between ACTH levels and stroke index. (α-melanocyte-stimulating hormone appears to have a vasodilative effect during sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980919"}
{"pmid": "20980912", "title": "Hemodynamic and metabolic effects of para- versus intraaortic counterpulsatile circulation supports.", "content": "Hemodynamic and metabolic effects of para- versus intraaortic counterpulsatile circulation supports. Despite the success of intraaortic balloon counterpulsation, data on physiologic indices and optimal inflation/deflation timing control of chronic counterpulsation devices are unclear. This study explored the acute hemodynamic and metabolic efficacy of a novel 40-ml stroke volume paraaortic blood pump (PABP) versus a standard intraaortic balloon pump (IABP). Acute porcine model was used with eight pigs randomly divided into PABP (n = 4) and IABP (n = 4) groups. Hemodynamic and metabolic measurements were obtained with and without mechanical assistance. In one pig, the inflation/deflation control was adjusted to different settings, with corresponding performance indices measured. The PABP significantly improved classical counterpulsation indices (p ≤ 0.05) and achieved an average beneficial effect on these indices 1.5-3.5 times greater than that of the IABP. Classical metabolic indices (tension time index and endocardial viability ratio [EVR]), and indices new to chronic counterpulsation research (coronary perfusion, left ventricular stroke work (SW), and a newly derived EVR) were also used in assessment. Both IABP assistance and PABP assistance improved these physiologic indices, with a trend toward PABP superiority in reducing left ventricular SW (p = 0.08). An optimal PABP deflation timing occurs during systole (25 milliseconds after the R-wave) and can minimize coronary regurgitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980912"}
{"pmid": "20980920", "title": "The effect of St John's Wort on the pharmacodynamic response of clopidogrel in hyporesponsive volunteers and patients: increased platelet inhibition by enhancement of CYP3A4 metabolic activity.", "content": "The effect of St John's Wort on the pharmacodynamic response of clopidogrel in hyporesponsive volunteers and patients: increased platelet inhibition by enhancement of CYP3A4 metabolic activity. Clopidogrel is metabolically activated by cytochrome P450 (CYP) isoenzymes. We evaluated whether St. John's wort (SJW), a CYP2C19 and CYP3A4 inducer, enhances the pharmacodynamic response of clopidogrel. Volunteers (n = 45) were screened for clopidogrel hyporesponsiveness after a 300-mg load. After a 7-day washout, hyporesponders (n = 10) received 14 days of SJW (300 mg 3 times a day) followed by a second 300-mg clopidogrel. Platelet aggregation was measured at 0, 2, 4, and 6 hours postloading; hepatic CYP3A4 activity was simultaneously determined at 0 and 4 hours by the erythromycin breath test. A prospective, randomized, double-blind pilot study was conducted in postcoronary stent patients (n = 85) on clopidogrel 75 mg/d screened for clopidogrel hyporesponsiveness. Hyporesponders (n = 20) were randomized to SJW (n = 10) or placebo (n = 10); platelet aggregation was measured before and after 14 days of therapy. In volunteers, SJW decreased platelet aggregation (59% ± 14% vs. 40% ± 15% at 2 hours, P = 0.02; 56% ± 10% vs. 44% ± 13% at 4 hours, P < 0.03; and 55% ± 14% vs. 37% ± 14% at 6 hours, P = 0.01) and increased CYP3A4 activity (2.1% ± 0.4% CO2 exhaled per hour before vs. 2.9% ± 0.6% CO2 exhaled per hour after SJW, P = 0.002). In patients, SJW decreased platelet reactivity (226 ± 39 vs. 185 ± 49 P2Y12 reactivity units, P = 0.0002) and increased platelet inhibition (23% ± 11% vs. 41% ± 16%, P = 0.002). SJW may be a future therapeutic option to increase CYP metabolic activity and antiplatelet effect of clopidogrel in hyporesponders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980920"}
{"pmid": "20980921", "title": "Electrophysiological properties of HBI-3000: a new antiarrhythmic agent with multiple-channel blocking properties in human ventricular myocytes.", "content": "Electrophysiological properties of HBI-3000: a new antiarrhythmic agent with multiple-channel blocking properties in human ventricular myocytes. HBI-3000 (sulcardine sulfate) has been shown to suppress various ventricular arrhythmias in animal models. The electrophysiological properties of HBI-3000 were investigated using standard microelectrode and patch-clamp techniques in single human ventricular myocytes. HBI-3000 led to concentration-dependent suppression of dofetilide-induced early afterdepolarizations in single nonfailing human ventricular myocytes and early afterdepolarizations seen in failing ventricular myocytes. The concentration-dependent prolongation of action potential duration (APD) by HBI-3000 was bell shaped with maximum response occurring around 10 μM. Interestingly, HBI-3000 at the concentration of 10 μM modestly prolonged the APD at all 3 basic cycle lengths. The slope of APD-cycle length curve of HBI-3000 was only slightly steeper than that of control (88.8 ± 7.7 ms/s vs. 78.9 ± 5.2 ms/s in control, n = 8, P > 0.05). HBI-3000 only showed a minimal use-dependent prolongation of the APD in human ventricular myocytes. HBI-3000 inhibited fast sodium current (INa-F), late sodium channel (INa-L), L-type calcium current (ICa-L), and rapidly activating delayed rectifier K current (IKr) in single human ventricular myocytes. The estimated half-maximal inhibitory concentration values of INa-F, INa-L, ICa-L, and IKr were 48.3 ± 3.8, 16.5 ± 1.4, 32.2 ± 2.9, and 22.7 ± 2.5 μM, respectively. The ion channel profile and electrophysiological properties of HBI-3000 are similar to those of ranolazine and chronic amiodarone (reduced INa-F, INa-L, ICa-L, and IKr). HBI-3000 may be a promising antiarrhythmic agent with low proarrhythmic risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980921"}
{"pmid": "20980924", "title": "Elite sprinting: are athletes individually step-frequency or step-length reliant?", "content": "Elite sprinting: are athletes individually step-frequency or step-length reliant? The aim of this study was to investigate the step characteristics among the very best 100-m sprinters in the world to understand whether the elite athletes are individually more reliant on step frequency (SF) or step length (SL). A total of 52 male elite-level 100-m races were recorded from publicly available television broadcasts, with 11 analyzed athletes performing in 10 or more races. For each run of each athlete, the average SF and SL over the whole 100-m distance was analyzed. To determine any SF or SL reliance for an individual athlete, the 90% confidence interval (CI) for the difference between the SF-time versus SL-time relationships was derived using a criterion nonparametric bootstrapping technique. Athletes performed these races with various combinations of SF and SL reliance. Athlete A10 yielded the highest positive CI difference (SL reliance), with a value of 1.05 (CI = 0.50-1.53). The largest negative difference (SF reliance) occurred for athlete A11 as -0.60, with the CI range of -1.20 to 0.03. Previous studies have generally identified only one of these variables to be the main reason for faster running velocities. However, this study showed that there is a large variation of performance patterns among the elite athletes and, overall, SF or SL reliance is a highly individual occurrence. It is proposed that athletes should take this reliance into account in their training, with SF-reliant athletes needing to keep their neural system ready for fast leg turnover and SL-reliant athletes requiring more concentration on maintaining strength levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980924"}
{"pmid": "20980922", "title": "Role of microRNAs in cardiac preconditioning.", "content": "Role of microRNAs in cardiac preconditioning. Preconditioning (PC) of the heart by sublethal ischemia, mild heat shock, or hypoxia has evolved as a powerful experimental tool to discover novel signaling mechanisms in cardioprotection. The ultimate goal is to determine novel therapeutic targets for potential application in humans to protect the heart against ischemia-related injuries. In recent years, there has been a tremendous interest in understanding the role of small noncoding RNAs, microRNAs (miRs), in cardiovascular diseases. miRs have been recognized as regulators of gene expression by destabilization and translational inhibition of target messenger RNAs. Studies have shown that several miRs, including miR-1, miR-133, miR-21, miR-126, miR-320, miR-92a, and miR-199a, are regulated after preconditioning and play an active role in protecting the heart against ischemia/reperfusion injury. These miRs also drive the synthesis of important cardioprotective proteins including heat shock protein (HSP)-70, endothelial nitric oxide synthase, inducible nitric oxide synthase, HSP-20, Sirt1, and hypoxia-inducible factor 1a. We believe that identification and targeted delivery of miR(s) in the heart could have an immense therapeutic potential in reducing myocardial infarction in patients suffering from heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980922"}
{"pmid": "20980925", "title": "Body mass, training, menses, and bone in adolescent runners: a 3-yr follow-up.", "content": "Body mass, training, menses, and bone in adolescent runners: a 3-yr follow-up. Endurance runners with low bone mass during adolescence may risk attaining a low peak bone mineral density (BMD) in adulthood. Alternatively, they may mature late and undergo delayed bone mineral accumulation. The purpose of this study was to evaluate 40 adolescent runners (aged 15.9 ± 0.2 yr) at two time points, approximately 3 yr apart, to assess bone mass status and identify variables associated with bone mass change. Follow-up measures included a questionnaire to assess menstrual status, training, and sports participation history, height and weight, and a dual-energy x-ray absorptiometry scan to assess total body, total hip, and lumbar spine BMD, bone mineral content (BMC), BMD z-score, and body composition. We used -1 and -2 BMD z-score cutoffs to categorize runners with low bone mass. Eighty-seven percent of girls with low BMD at baseline had low BMD at the follow-up. Girls with low compared with normal baseline BMD had lower follow-up adjusted total body (2220.4 ± 65.8 vs 2793.1 ± 68.2 g, P < 0.001), total hip (27.0 ± 1 vs 33.9 ± 1.0 g, P < 0.05), and lumbar spine (47.8 ± 2.0 vs 66.3 ± 2.2 g, P < 0.001) BMC values. Variables related to 3-yr training volume, menstrual function, age, developmental stage, and change in body mass explained 29%-54% of the variability in BMC change. The majority of adolescent runners with low BMD at baseline had low BMD after a 3-yr follow-up. Our observations suggest that \"catch-up\" accrual may be difficult and, thus, emphasize the importance of gaining adequate bone mineral during the early adolescent years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980925"}
{"pmid": "20980923", "title": "Effects of whole-body vibration training on different devices on bone mineral density.", "content": "Effects of whole-body vibration training on different devices on bone mineral density. Whole-body vibration (WBV) is a new nonpharmacological approach to counteract osteoporosis. However, the specific vibration protocol to most effectively reduce osteoporotic risk has not been reported. In the ELVIS II (Erlangen Longitudinal Vibration Study II) trial, we determined the effect of different WBV devices on bone mineral density (BMD) and neuromuscular performance. A total of 108 postmenopausal women (65.8 ± 3.5 yr) were randomly allocated to 1) rotational vibration training (RVT), i.e., 12.5 Hz, 12 mm, three sessions per week, for 15 min, including dynamic squat exercises; 2) vertical vibration training (VVT), i.e., 35 Hz, 1.7 mm, as above; and 3) a wellness control group (CG), i.e., two blocks of 10 low-intensity gymnastics sessions. BMD was measured at the hip and lumbar spine at baseline and after 12 months of training using dual-energy x-ray absorptiomety. Maximum isometric leg extension strength and leg power were determined using force plates. A BMD gain at the lumbar spine was observed in both vibration VT groups (RVT = +0.7% ± 2.2%, VVT = +0.5% ± 2.0%), which was significant compared with the CG value (-0.4% ± 2.0%) for RVT (P = 0.04) and borderline nonsignificant for VVT (P = 0.08). In the neck region, no significant treatment effect occurred. Neck BMD values tended to increase in both VT groups (RVT = +0.3% ± 2.7%, VVT = +1.1% ± 3.4%) and remained stable in CG (-0.0% ± 2.1%).Both VT groups gained maximum leg strength (RVT = +27% ± 22%, VVT = +24% ± 34%) compared with CG (+6% ± 20%, P = 0.000), whereas power measurements did not reach the level of significance (P = 0.1). WBV training is effective for reducing the risk for osteoporosis by increasing lumbar BMD and leg strength.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980923"}
{"pmid": "20980927", "title": "Hormonal responses to resistance exercise during different menstrual cycle states.", "content": "Hormonal responses to resistance exercise during different menstrual cycle states. To investigate the effect of menstrual cycle states on ovarian and anabolic hormonal responses to acute resistance exercise in young women. Eight healthy women (eumenorrhea; EM) and eight women with menstrual disorders including oligomenorrhea and amenorrhea (OAM) participated in this study. The EM group performed acute resistance exercises during the early follicular (EF) and midluteal (ML) phases, and the OAM group performed the same exercises. All subjects performed three sets each of lat pull-downs, leg curls, bench presses, leg extensions, and squats at 75%-80% of one-repetition maximum with a 1-min rest between sets. Blood samples were obtained before exercise, immediately after, 30 min after, and 60 min after the exercise. In the EM group, resting serum levels of estradiol and progesterone in the ML phase were higher than those in the EF phase and higher than those in the OAM group. Serum estradiol and progesterone in the ML phase increased after the exercise but did not change in the EF phase or in the OAM group. In contrast, resting levels of testosterone in the OAM group were higher than those in both the ML and EF phases of the EM group. After the exercise, serum growth hormone increased in both the ML and EF phases but did not change in the OAM group. The responses of anabolic hormones to acute resistance exercise are different among the menstrual cycle states in young women. Women with menstrual disturbances with low estradiol and progesterone serum levels have an attenuated anabolic hormone response to acute resistance exercise, suggesting that menstrual disorders accompanying low ovarian hormone levels may affect exercise-induced change in anabolic hormones in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980927"}
{"pmid": "20980926", "title": "Effectiveness of sulfur-containing antioxidants in delaying skeletal muscle fatigue.", "content": "Effectiveness of sulfur-containing antioxidants in delaying skeletal muscle fatigue. Reactions involving thiol biochemistry seem to play a crucial role in skeletal muscle fatigue. N-acetylcysteine amide (NACA) and L-ergothioneine (ERGO) are thiol-based antioxidants available for human use that have not been evaluated for effects on muscle fatigue. To test the hypothesis that NACA and ERGO delay skeletal muscle fatigue. We exposed mouse diaphragm fiber bundles to buffer (CTRL), NACA, ERGO, or N-acetylcysteine (NAC; positive control). Treatments were performed in vitro using 10 mM for 60 min at 37 °C. After treatment, we determined the muscle force-frequency and fatigue characteristics. The force-frequency relationship was shifted to the left by ERGO and to the right by NACA compared with CTRL and NAC. Maximal tetanic force was similar among groups. The total force-time integral (FTI; N · s · cm) during the fatigue trial was decreased by NACA (420 ± 35, P < 0.05), unaffected by ERGO (657 ± 53), and increased by NAC (P < 0.05) compared with CTRL (581 ± 54). The rate of contraction (dF/dtMAX) during the fatigue trial was not affected by any of the treatments tested. NAC, but not NACA or ERGO, delayed the slowing of muscle relaxation (dF/dtMIN) during fatigue. In summary, NACA and ERGO did not delay skeletal muscle fatigue in vitro. We conclude that these antioxidants are unlikely to improve human exercise performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980926"}
{"pmid": "20980929", "title": "Pelvic reconstruction with mesh for advanced pelvic organ prolapse: a new economic surgical method.", "content": "Pelvic reconstruction with mesh for advanced pelvic organ prolapse: a new economic surgical method. The aim of this study was to introduce a new pelvic reconstructive surgical operation with use of specially designed puncture needles and precut mesh. In addition, the anatomic results and the safety of this reconstructive approach were evaluated. Ninety-nine women who were older than 60 years with stage III or IV prolapse according to pelvic organ prolapse quantification (POP-Q) underwent the modified pelvic reconstructive surgical operation. Follow-up was more than 1 year. The objective and subjective results were measured by POP-Q and quality-of-life questionnaires, respectively. Complications were also observed both in the surgical operation and in the follow-up examination. No severe intraoperative complications were observed. POP-Q measurements of Ba, Bp, and C taken 1 year postoperatively were significantly improved compared with those at baseline (P < 0.001), but eight women (8.1%) showed recurrence. A significant improvement in quality-of-life scores was observed (P < 0.001). The incidence rate of mesh exposure and the de novo urgent incontinence rates were 2% and 12%, respectively. This new pelvic reconstructive surgical operation is a cost-effective and safe method and is easy to perform.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980929"}
{"pmid": "20980928", "title": "Relationship of television time with accelerometer-derived sedentary time: NHANES.", "content": "Relationship of television time with accelerometer-derived sedentary time: NHANES. To examine the relationship of self-reported television (TV) viewing time with accelerometer-derived total sedentary time and to determine whether it differs by subgroup. Using data for adults (≥20 yr) from the 2003-2004 and 2005-2006 nationally representative US National Health and Nutrition Examination Surveys (NHANES; n=5738), linear regression models examined the associations of categories of self-reported TV viewing time (<1, 1, 2, 3, 4, and >5 h·d) with accelerometer-derived sedentary time (<100 counts per minute; h·d). Spearman ρ assessed the correlation between participants' rankings on the two measures. Analyses were stratified by gender, age, race/ethnicity, and, in the 2003-2004 NHANES cycle, by work status among working-aged adults (20-65 yr, n=2069). TV viewing time was significantly associated with sedentary time, with positive associations for all gender, age, race/ethnicity groups, and for those not working or working part-time, but not for those in full-time work. However, correlations between rankings of the measures were only \"fair\" overall (ρ=0.22) and were similar for all gender and racial/ethnic groups and for those of mid- and older age but not for those of younger age (20-39 yr, ρ=0.05). In the working-aged subgroup, there was also a fair correlation between the measures for those not working (ρ=0.22) but no significant correlation for those in part-time (ρ=0.14) or full-time work (ρ=0.03). Associations of TV viewing time with accelerometer-derived total sedentary time were statistically significant, but correlations were of only fair magnitude, and the strength of the relationship was not consistent across all population subgroups. These findings suggest that TV viewing time has an influence on overall sedentary time at a population level; however, measurement of sedentary time in other domains is also important.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980928"}
{"pmid": "20980930", "title": "Overexpression of piccolo C2A domain induces depression-like behavior in mice.", "content": "Overexpression of piccolo C2A domain induces depression-like behavior in mice. Piccolo is one of the components of the active zone at chemical synapses and regulates the transport of synaptic vesicles. The piccolo C2A domain is an important calcium sensor and binds with phosphatidylinositol or synaptotagmin-1. Recently, clinical studies suggested that a single nucleotide polymorphism in the piccolo C2A domain might be a causal risk factor for major depression. To clarify the association of piccolo with depression, we produced a transgenic mouse overexpressing the C2A domain of piccolo, and investigated the behavior of these mice. The mice exhibited depression-like behavior in both forced swim and tail suspension tests, suggesting that piccolo might regulate the depressive behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980930"}
{"pmid": "20980931", "title": "The relationship between respiratory viral loads and diagnosis in children presenting to a pediatric hospital emergency department.", "content": "The relationship between respiratory viral loads and diagnosis in children presenting to a pediatric hospital emergency department. respiratory viral infections account for a considerable proportion of pediatric emergency room visits. Illnesses range in severity from mild upper respiratory tract infections to serious lower respiratory tract infections (LRTI). The relationship between viral load and specific viruses to clinical diagnosis made by physicians in this setting is poorly understood. we applied a real-time, quantitative polymerase chain reaction (qPCR) panel for 13 common respiratory viruses to 195 frozen, archival nasopharyngeal aspirate specimens obtained from symptomatic children ≤ 4 months of age presenting to the emergency room. Mean total viral load and number of viruses per archival nasopharyngeal aspirate specimen were compared between LRTI (n = 70) and non-LRTI (1 or more of upper respiratory tract infection, fever, or cough) (n = 125), as were yield and concordance of qPCR results to viral culture/direct fluorescence assay (DFA). children with LRTI had significantly increased total viral load and harbored more viruses than the non-LRTI group. Respiratory syncytial virus-A and -B were significantly associated with LRTI, and parainfluenza virus-1 with non-LRTI. Individual loads of parainfluenza virus-2 and human rhinovirus were increased in LRTI versus non-LRTI. Quantitative PCR yielded more viruses (including coinfections, where a \"dominant virus\" was typically identified) than viral culture/DFA and documented nucleic acid from pathogens not tested by culture/DFA including human rhinovirus; coronaviruses -OC43, -229E, and -NL63; and metapneumovirus. in symptomatic children presenting to the emergency room, total viral load is related to clinical diagnosis; specific viruses are associated with particular clinical diagnoses, and qPCR has a higher yield than other viral diagnostic methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980931"}
{"pmid": "20980932", "title": "Altered gentamicin serum concentrations in obese pediatric patients.", "content": "Altered gentamicin serum concentrations in obese pediatric patients. We performed a retrospective case-cohort study of 50 obese pediatric patients aged 2 to 18 years who received scheduled gentamicin therapy, with serum peak and trough concentrations measured. Obese pediatric patients had significantly higher gentamicin serum peak and trough concentrations despite receiving significantly lower mg/kg of actual body weight doses of gentamicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980932"}
{"pmid": "20980933", "title": "Safety and immunogenicity of a booster dose of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine coadministered with DTPw-HBV/Hib and poliovirus vaccines.", "content": "Safety and immunogenicity of a booster dose of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine coadministered with DTPw-HBV/Hib and poliovirus vaccines. The safety and reactogenicity profiles of the 10-valent pneumococcal conjugate vaccine, PHiD-CV, and 7vCRM were comparable within the Philippines and Poland when coadministered as a booster dose with DTPw-HBV/Hib and poliovirus vaccines to toddlers primed with the same vaccines. Robust immune responses for all 10 vaccine pneumococcal serotypes and protein D following PHiD-CV booster vaccination were indicative of effective priming.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980933"}
{"pmid": "20980934", "title": "2010 Dietary Guidelines. Updated recommendations put focus on obesity.", "content": "2010 Dietary Guidelines. Updated recommendations put focus on obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980934"}
{"pmid": "20980935", "title": "New criteria proposes using pain, symptoms to diagnose fibromyalgia.", "content": "New criteria proposes using pain, symptoms to diagnose fibromyalgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980935"}
{"pmid": "20980936", "title": "Women who eat healthy diets may lower risk of cataracts.", "content": "Women who eat healthy diets may lower risk of cataracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980936"}
{"pmid": "20980937", "title": "Radon. Protect yourself from an invisible threat.", "content": "Radon. Protect yourself from an invisible threat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980937"}
{"pmid": "20980938", "title": "Mayo Clinic office visit. Raynaud's disease. An interview with Kevin Moder, M.D.", "content": "Mayo Clinic office visit. Raynaud's disease. An interview with Kevin Moder, M.D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980938"}
{"pmid": "20980939", "title": "Interval training. Boost your fitness in quick bursts.", "content": "Interval training. Boost your fitness in quick bursts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980939"}
{"pmid": "20980940", "title": "Are older people more sensitive to cold weather?", "content": "Are older people more sensitive to cold weather?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980940"}
{"pmid": "20980941", "title": "Does trigeminal neuralgia always get worse over time?", "content": "Does trigeminal neuralgia always get worse over time?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980941"}
{"pmid": "20980942", "title": "New once-daily, long-acting inhaled β₂-agonist: what role will it play in the treatment of chronic obstructive pulmonary disease?", "content": "New once-daily, long-acting inhaled β₂-agonist: what role will it play in the treatment of chronic obstructive pulmonary disease?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980942"}
{"pmid": "20980944", "title": "Subclinical organ damage in perimenopausal women with essential hypertension.", "content": "Subclinical organ damage in perimenopausal women with essential hypertension. Hypertension and its complications are more common in postmenopausal women than before menopause. However, whether this is due to the effect of age or menopause is still unknown. The aim of the study was to assess the effect of menopause on blood pressure (BP), left ventricular and vascular structure and function, as well as kidney function in perimenopausal women. The study involved 192 women aged 40 to 60 years (mean age, 51.73 ±1.82 years), including 152 with newly diagnosed essential hypertension and 40 normotensive controls matched for age. In all subjects, 24-hour BP monitoring was performed. Echocardiographic examination with the assessment of left ventricular mass (LVM) and systolic and diastolic function,as well as carotid ultrasound with the measurement of intima-media thickness (IMT) in the common carotid artery were performed. Carotid-femoral pulse wave velocity (PWV) was measured. Glomerular filtration rate (eGFR) was calculated and urinary albumin-creatinine ratio (UACR) was measured. The study group was divided according to hypertension and menopausal status into 4 subgroups: normotensive premenopausal, normotensive postmenopausal, hypertensive premenopausal, and hypertensive postmenopausal women. Menopause did not affect BP or LVM. Differences in LVM between pre- and postmenopausal women were dependent on age and the body mass index. Hypertensive postmenopausal compared with hypertensive premenopausal women had significantly higher IMT (0.72 ±0.34 mm vs. 0.59 ±0.30 mm, P = 0.001) and a lower ratio of early to late mitral inflow velocity (E/A, 1.04 ±0.32 vs. 1.32 ±0.33, P = 0.01). PWV was higher in hypertensives compared to controls (9.7 ±1.6 m/s vs. 8.4 ±1.2 m/s, P = 0.001), without differences between premenopausal and postmenopausal women. Menopause did not affect eGFR and UACR either in the hypertensive or normotensive group. Left ventricular diastolic function and carotid IMT are independently associated with menopausal status in both normo- and hypertensive women. Menopause per se did not affect BP in the examined group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980944"}
{"pmid": "20980943", "title": "N-acetylcysteine fails to prevent renal dysfunction and oxidative stress after noniodine contrast media administration during percutaneous coronary interventions.", "content": "N-acetylcysteine fails to prevent renal dysfunction and oxidative stress after noniodine contrast media administration during percutaneous coronary interventions. Oxidative stress is believed to have a role in contrast-induced nephropathy. Based on this assumption, several known antioxidants have been studied to assess their effect on nephropathy, especially N-acetylcysteine (NAC). However, its usefulness has yet to be confirmed. We aimed to assess whether NAC has any protective effect on contrast-induced renal dysfunction, and whether NAC affects the parameters of oxidative stress in serum and urine. Sixty patients with coronary artery disease, who presented for an elective percutaneous coronary intervention (PCI), were randomized into 2 groups in an age- and gender-matched fashion: one group received 600 mg intravenous NAC and the other did not. Before and 24 hours after the procedure, blood and urine samples were obtained to assess total oxidant capacity (TOC), total antioxidant capacity (TAC), oxidative stress index (OSI), and renal function. Twenty-four hours after PCI, TOC and OSI levels were significantly increased and TAC levels significantly decreased, both in serum and urine. However, we did not observe any differences in oxidative parameters between patients who received NAC and those who did not. Multivariate analyses identified no protective effect of NAC on renal function, and no effect on oxidative parameters in either serum or urine. In this first clinical study that determined TOC and TAC levels in both serum and urine after exposure to contrast media, NAC was not found to affect oxidant parameters or protect against contrast nephropathy, at least in patients without the risk factors for nephropathy, such as diabetes mellitus or baseline renal or cardiac dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980943"}
{"pmid": "20980945", "title": "Association between glycemic control and the level of knowledge and disease awareness in type 2 diabetic patients.", "content": "Association between glycemic control and the level of knowledge and disease awareness in type 2 diabetic patients. Diabetes-related complications may be prevented if good metabolic control is achieved. In addition to drug therapy, patient education may facilitate better glycemic control. The aim of the study was to assess the relationship between glycemic control and effective diabetes education using the knowledge and awareness (KA) questionnaire in type 2 diabetic patients. Moreover, the effect of age, duration of diabetes, sex, body mass index (BMI), and education level on glycemic control was assessed cross-sectionally. The study included 164 patients with type 2 diabetes. The KA questionnaire, adapted for Turkish population, was distributed among patients after establishing whether they received diabetes education. Associations between the questionnaire scores and glycated hemoglobin (HbA(1c)), fasting blood glucose (FBG), and BMI were assessed. A significant negative correlation was observed between KA scores and HbA(1c) and FBG levels. Sixty-three patients had received diabetes education. These patients had higher KA scores compared with the remaining group (24.0 ±4.0 vs. 16.8 ±5.37, respectively; P <0.0001) and lower HbA1c levels (6.5% vs. 8.5%, respectively; P <0.0001). In type 2 diabetic patients, the higher the KA score, the more efficient glycemic control can be achieved. Patients who require diabetes education can be identified by using questionnaires that determine their KA level and by using HbA(1c) tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980945"}
{"pmid": "20980946", "title": "Aspirin chemoprevention of gastrointestinal cancer in the next decade. A review of the evidence.", "content": "Aspirin chemoprevention of gastrointestinal cancer in the next decade. A review of the evidence. Together, gastrointestinal (GI) cancers now account for 25% of neoplastic deaths in the West. In Poland, GI cancer rates are likely to increase further as westernization progresses. Given that conventional cancer therapies have made only modest reductions in cancer mortality, there is a great interest in chemoprevention to prevent or slow malignant transformation from premalignant lesions. The financial pressures in the immediate future require even more stringent criteria for chemopreventive agents - they must be cheap but also safe and efficacious. In this regard, several reviews have indicated that aspirin possesses many favorable qualities for chemoprevention. Furthermore, meta-analyses indicate that aspirin may decrease cancer by approximately 30%. Several large clinical trials are underway, including AspECT (Aspirin and Esomeprazole Chemoprevention Trial) that aims not only to prevent cancer but also decrease the gastric side effects by combining aspirin with potent acid-suppressing drugs. In conclusion, whether aspirin will be the world's first proven chemopreventive agent is currently unknown but the evidence looks hopeful.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980946"}
{"pmid": "20980947", "title": "Progression of retinopathy in persons with type 2 diabetes: new data, same conclusions?", "content": "Progression of retinopathy in persons with type 2 diabetes: new data, same conclusions? The ACCORD (Action to Control Cardiovascular Risk in Diabetes) trial was designed primarily to examine the effects of intensive glycemic control on cardiovascular events in persons with type 2 diabetes who were, for additional reasons, at high risk for such events. The trial also examined effects on the same endpoints of intervention on blood pressure and on serum lipids. The study intervention on glycemic control was stopped early because of the effects of this intervention on mortality. The trial provided important data on the effects of the various interventions on diabetic retinopathy, confirming the importance of intensive glycemic control in diminishing the progression of retinopathy. In addition, it provided evidence of a protective effect of fenofibrate treatment on the same retinopathy endpoint. However, the apparent paradoxical effects of intensive glycemic control on macrovascular and microvascular disease suggests caution in the care of persons with type 2 diabetes who are judged to be at high risk for cardiovascular events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980947"}
{"pmid": "20980948", "title": "How should we treat tuberculosis in adult patients with chronic kidney disease? Key messages from the British Thoracic Society Guidelines.", "content": "How should we treat tuberculosis in adult patients with chronic kidney disease? Key messages from the British Thoracic Society Guidelines. This review highlights the key messages from the 2010 British Thoracic Society Guidelines on the management of Mycobacterium tuberculosis infection and disease in adult patients with chronic kidney disease. These guidelines were developed in response to many requests for advice from respiratory and infectious diseases physicians who treat patients with tuberculosis, as there was very little information available to help clinicians manage the disease in this population of often very sick patients. Renal units in the United Kingdom were prescribing variable chemoprophylaxis regimens that frequently had no basis in evidence, and drug doses used to treat tuberculosis were often inappropriate because of clinicians' natural concern about poisoning a patient with little or no renal function. The guidelines address these issues together with when and how to screen for latent infection and the different needs of patients with renal impairment, those needing dialysis and those with a transplanted kidney. It became very clear in compiling these guidelines that there is a shortage of both background information on rates of tuberculosis in such patients in countries with low background prevalence, and good randomized controlled trials of treatment regimens. Wherever possible, the recommendations made are evidence-based, but this was not always available. This review gives a summary of those recommendations and reiterates some of the important messages; in particular, tuberculosis should be managed with the full involvement of the chest or infectious diseases physician who is the local lead for this important infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980948"}
{"pmid": "20980949", "title": "Integrated care for patients with advanced chronic obstructive pulmonary disease: a new approach to organization.", "content": "Integrated care for patients with advanced chronic obstructive pulmonary disease: a new approach to organization. Chronic obstructive pulmonary disease (COPD) affects approximately 10% of the population aged above 40 years. In advanced COPD (forced expiratory volume in 1 second <50% of the predicted value), patients suffer from severe pulmonary symptoms including dyspnea, chronic cough, poor exercise tolerance, which are commonly associated with systemic disorders, such as osteoporosis, loss of fat-free body mass, fatigue, anxiety, and depression. Moreover, patients with advanced COPD experience annually an average of 2 to 3 episodes of exacerbations requiring hospitalization. We present here a model of integrated care based on the cooperation between medical staff, social workers, volunteers and patients and their families. The essential components of this model are intensive education, treatment supervision, and support in self-management as well as coping with the disease and its consequences. It is expected that these measures will result in a decreased number of exacerbations requiring hospitalization, improved disease course, and better quality of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980949"}
{"pmid": "20980950", "title": "The antimicrobial and phagocytic defense mechanisms of the terrestrial gastropod Lehmannia nyctelia against Escherichia coli and Staphylococcus aureus.", "content": "The antimicrobial and phagocytic defense mechanisms of the terrestrial gastropod Lehmannia nyctelia against Escherichia coli and Staphylococcus aureus. Gastropods are significant vectors of human infectious diseases and are exposed to a wide range of soil parasites and micro-organisms. To defend against infection, we hypothesized that the slug produces both soluble and cellular defense mechanisms. In the gastropod Lehmannia nyctelia, soluble antimicrobial activity was measured by disk diffusion assay and phagocytosis was measured by in vitro and in vivo uptake of fluorescent Escherichia coli bioparticles. In disk diffusion assays we failed to observe either methanol or dimethylsulfoxide soluble material in the slug secretions and tissues. However, isolation of the slug skin cells demonstrated phagocytic morphology in vitro when exposed to Escherichia coli and Staphylococcus aureus and internalization of fluorescent Escherichia coli bioparticles. Further, examination of histological sections of a slug exposed to fluorescent Escherichia coli bioparticles revealed a subset of skin cells which had cytoplasmic accumulations of the bioparticles. These data suggest that the Lehmannia nyctelia skin contains active phagocytic cells that may affect the set of parasites and microbes for which slugs can serve as vectors of disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980950"}
{"pmid": "20980951", "title": "Identification of a µ opiate receptor signaling mechanism in human placenta.", "content": "Identification of a µ opiate receptor signaling mechanism in human placenta. Previous studies report that genes in the morphine biosynthetic pathway have been found in placental tissue. Prior researchers have shown that kappa opioid receptors are present in human placenta. We determined if a µ opiate receptor was present and which subtype was expressed in human placenta. We also sought to demonstrate a functional µ opiate receptor in human placenta. Polymerase chain reactions as well as DNA sequencing were performed to identify the µ opiate receptor subtypes present in human placenta. The functionality of the receptor was demonstrated by real time amperometric measurements of morphine induced NO release. The µ4 opiate receptor sequence was present as well as the µ1 opioid receptor transcript. The addition of morphine to placental tissue resulted in immediate nitric oxide release and this effect was blocked by naloxone. In the present study, an intact morphine signaling system has been demonstrated in human placenta. Morphine signaling in human placenta probably functions to regulate the immune, vascular, and endocrine functions of this organ via NO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980951"}
{"pmid": "20980952", "title": "Taxol, a microtubule stabilizer, prevents atrial fibrillation in in vitro atrial fibrillation models using rabbit hearts.", "content": "Taxol, a microtubule stabilizer, prevents atrial fibrillation in in vitro atrial fibrillation models using rabbit hearts. Increased atrial oxidative stress plays an important role in the pathogenesis of atrial fibrillation. A predisposition for atrial fibrillation can be produced by altering the activities of enzymes related to reactive oxygen species metabolism. Microtubule integrity is necessary for cardio-protection; microtubules are involved in many cellular processes, including enzymatic activity. Taxol, a common microtubule stabilizer, can protect cardiac myocytes from oxidative stress. However, its effects on atrial fibrillation remain unknown. In vitro rabbit heart models of ischemia-, stretch-, and cholinergic agitation-induced atrial fibrillation were developed. Using either a fluorometric or spectrophotometric assay, we measured reactive oxygen species and the activities of oxidative enzymes including nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, xanthine oxidase, mitochondrial electron transport chain complexes I, mitochondrial electron transport chain complexes III, and superoxide dismutase. Taxol effectively reduced the incidence of ischemia-, stretch- and cholinergic agitation-induced atrial fibrillation in in vitro rabbit heart models by 50%, 60%, and 40%. Moreover, Taxol decreased the level of reactive oxygen species by 46%, 49%, and 70% in ischemia-, stretch- and cholinergic agitation-induced atrial fibrillation models. Additionally, the activities of NADPH oxidase and xanthine oxidase were increased, whereas those of mitochondrial electron transport chain complexes I and III and superoxide dismutase were not affected. Taxol, a microtubule stabilizer, prevents atrial fibrillation in in vitro atrial fibrillation model using rabbit hearts. This stabilizer most likely prevents atrial fibrillation by reducing the level of reactive oxygen species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980952"}
{"pmid": "20980953", "title": "Plasma inhibin B and antimüllerian hormone concentrations in boys: discriminating between congenital hypogonadotropic hypogonadism and constitutional pubertal delay.", "content": "Plasma inhibin B and antimüllerian hormone concentrations in boys: discriminating between congenital hypogonadotropic hypogonadism and constitutional pubertal delay. Inhibin B and antimüllerian hormone (AMH) are secreted by the Sertoli cells, stimulated by gonadotropins. We evaluated their use for discriminating between congenital hypogonadotropic hypogonadism (HH) and constitutional pubertal delay. Group 1 (n=39) was diagnosed with constitutional pubertal delay; group 2 (n=15), isolated HH; and group 3, pituitary stalk interruption syndrome (3a with [n=5] and 3b [n=8] without HH). At pubertal age, mean plasma inhibin B concentrations were similar in the groups having the same gonadotropin status. Individual concentrations were normal in groups 1 and 3b, but low in 6 group 2, and 3 group 3a patients. Four group 2, and 1 group 3a, also had low AMH. Among these 9 with low inhibin B, 1 in each group evaluated before puberty had had normal inhibin B and AMH. In contrast, inhibin B increased (P<.03) and AMH decreased (P<.02) in 7 group 3b patients from before to after puberty. There were 20 patients with inhibin B below 100 pg/mL including 4 group 1, 13 group 2, and 3 group 3a. The basal plasma follicle stimulating (FSH) and luteinizing (LH) hormone concentrations were < 1 IU/L in 18%, 36% in group 1, and in 56% and 100% in group 2. Before puberty, plasma inhibin B and AMH concentrations may be normal despite HH. At pubertal age, both are low in some patients with HH. These hormone values may help discriminate between HH and constitutional pubertal delay together with plasma FSH and LH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980953"}
{"pmid": "20980954", "title": "Development of a surgical algorithm and optimized management of complications - based on a review of 706 abdominal free flaps for breast reconstruction.", "content": "Development of a surgical algorithm and optimized management of complications - based on a review of 706 abdominal free flaps for breast reconstruction. Microsurgical free flaps are a common method of breast reconstruction. Our institutional experiences with 706 lower abdomen based free perforator flaps are reported with special interest in presenting a therapeutic algorithm for efficient decision-making. A retrospective chart review was performed. All patients undergoing free flap surgery for breast reconstruction between July 2004 and November 2009 were included. Seven hundred and six free flaps were performed in 635 patients: 451 DIEAP-flaps, 254 fasciasparing (fs) TRAM-flaps and one SIEA flaps were performed. Five hundred sixty four women had a unilateral and 71 a bilateral reconstruction (142 flaps). The complication rate was 0.84% (6 flaps) for total flap loss, 1.27% (9 flaps) for partial flap loss and 2.40% (17 flaps) for partial flap loss less than 20%. 7 patients (1.11%) underwent microsurgical revision, where venous problems occurred. 3 of them were successful, in two cases a partial flap loss less than 30% occurred after the revision. In 2 cases a complete flap loss appeared. Other minor complications included: 23 patients (3.65%) had breast hematomas, 18 patients (2.54%) presented with delayed wound healing (9 abdominal and 9 breast delayed wound healings), and 3 patients (0.42%) with abdominal hernias, 14 patients (1.98%) complained of weakness of abdominal wall. Abdominally based free flaps a safe and reliable method and should therefore be offered as a standard method in a breast cancer center. The protocol and algorithm presented here can reduce complications in microsurgical breast reconstructive surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980954"}
{"pmid": "20980955", "title": "Pulsed perfusion in a venous human organ culture model with a Windkessel function (pulsed perfusion venous HOC-model).", "content": "Pulsed perfusion in a venous human organ culture model with a Windkessel function (pulsed perfusion venous HOC-model). The effectiveness of human saphenous vein grafting is limited by hyperplasia of the vessel wall. The current paper reports on a pulsed perfused venous human organ culture model (pp-venous HOC-model) with a Windkessel function. Saphenous vein grafts from 21 patients undergoing coronary bypass grafting were cultured either in venous or arterial hemodynamic conditions. Up to four vein segments were fixed in parallel connection and attached to a closed loop pulsed perfusion system consisting of large and small elastic tubes, mimicking the Windkessel function. First, after exposure to arterial blood pressure first signs of reactive cell proliferation (n.s.) were detected at day 4. Second, media thickness of the venous segments in the pulsed pressure group was decreased at day 4 (n.s.) and day 7 (n.s.). Third, staining against smooth muscle alpha actin and v. Willebrand factor was always positive at day 1, 4, and 7. Pulsed perfusion in a human venous organ culture model with a Windkessel function is an approach to better understand the events taking place during early arterial-vein grafting. First signs of reactive cell proliferation were detected at day four. A period of seven days as described in the current model is probably too short to detect reactive cell proliferation and medial thickening. If the device might be activated for a longer period of time, it should be a suitable model to characterize the effects of intra- and extravascular drug administration as treatment strategies of vein graft disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980955"}
{"pmid": "20980956", "title": "Comparative molecular epidemiology of Leishmania major and Leishmania tropica by PCR-RFLP technique in hyper endemic cities of Isfahan and Bam, Iran.", "content": "Comparative molecular epidemiology of Leishmania major and Leishmania tropica by PCR-RFLP technique in hyper endemic cities of Isfahan and Bam, Iran. Leishmania is an obligate intracellular protozoa, and the sandfly, as a vector, transmits infectious forms of the parasite to the vertebrate host. The etiologic agents of cutaneous leishmaniasis (CL), Leishmania major and Leishmania tropica, are the most prevalent factor in Iran, especially in the Isfahan and Bam regions. Because of the importance of CL in endemic regions and the interaction of species diversity factors in developing control strategies, several isolated Leishmania species from 2 hyperendemic regions of Iran, Isfahan and Bam cities, were examined in this study by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). In this study, 340 samples were taken from clinically suspected CL patients to prepare slides for direct microscopy and cultures for promastigotes by PCR-RFLP. The internal transcribed spacer 1 (ITS1) region of genomic DNA was extracted and amplified with LITSr and L5.8s primers. Amplification by PCR-RFLP was performed to determine 4 kinds of genotype pattern of the species in the 2 main cities of Isfahan and Bam. Some of the product samples were sequenced and analyzed. Two genotypic groups were detected from L. major isolates, LmA and LmB; also L. tropica showed 2 patterns, LtA and LtB, in comparison with standard species. The most prevalent genotypes related to isolates of Isfahan were LmA and of Bam were LtA. These 2 genotypes were recorded as major etiologic factors of CL in these 2 regions. Leishmania major and L. tropica, the causative agents of zoonotic CL and anthroponotic CL, respectively, in Isfahan and Bam, are genetically highly polymorphic species, and a correlation may exist between genetic heterogeneous and clinical manifestation and geographic regions of the disease in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980956"}
{"pmid": "20980957", "title": "Serum asymmetric dimethylarginine levels in normotensive obese individuals.", "content": "Serum asymmetric dimethylarginine levels in normotensive obese individuals. Obesity is associated with an increased risk of developing insulin resistance, hyperinsulinemia, glucose intolerance, dyslipidemia, hypertension, premature atherosclerosis, and coronary artery disease. This study is designed to compare serum asymmetric dimethylarginine (ADMA) levels between obese individuals and controls. Fifty volunteers, 30 obese (13 men; mean age, 40±11 years) and 20 healthy controls (13 men; mean age, 44±10 years) were enrolled to this study. Measurement of ADMA was accomplished by high performance liquid chromatography. The mean body mass index of the obese group was significantly higher than that of the control group (35±4 vs 26±3 kg/m2; P=.001). The mean waist circumference of the obese subjects was also significantly higher compared with controls (111±11 vs 93±10 cm; P=.001). No significant difference was found concerning age, sex, blood pressures, and biochemistry parameters. Serum ADMA levels were significantly higher in obese individuals compared with healthy controls (5.4±3.3 vs 3.1±1.8 µmol/L; P=.006). A weak but significant correlation was identified between serum ADMA concentration and the waist circumference (r=0.282, P=.047). The results of the present study demonstrated that serum ADMA levels of normotensive obese individuals were significantly higher than healthy controls. Increased ADMA concentrations observed only in the obese group were deemed to be important regarding the development future of cardiovascular disease in the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980957"}
{"pmid": "20980958", "title": "Integrating lung and plasma expression of pneumo-proteins in developing biomarkers in COPD: a case study of surfactant protein D.", "content": "Integrating lung and plasma expression of pneumo-proteins in developing biomarkers in COPD: a case study of surfactant protein D. Surfactant protein D (SP-D) is a promising blood biomarker in patients with chronic obstructive pulmonary disease (COPD). Nevertheless, circulating levels of SP-D are not related to pulmonary functions. In the present exploratory study, we created a simple index of plasma to bronchoalveolar lavage (BAL) fluid ratio of SP-D (pSP-D/bSP-D), and determined whether this index would relate to the severity of airflow limitation and hence represent a superior biomarker than pSP-D alone. In 50 ex and current smokers (mean age 57.6±7.8 years, 74% men), SP-D was measured in BAL fluid and plasma samples, and the relationships between spirometric variables and a composite parameter - the pSP-D/bSP-D ratio were determined. There was a significant inverse correlation between the pSP-D/bSP-D ratio and the severity of airflow obstruction, as measured by FEV1/FVC (p=0.012). In contrast, no relationship was observed between FEV1/FVC and pSP-D alone. We suggest that integrating both lung and plasma expression of pneumo-proteins may be more useful than plasma expression alone in developing pneumo-proteins as potential biomarkers in COPD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980958"}
{"pmid": "20980959", "title": "Association between documented coronary artery disease and urinary albumin, albumin to creatinine ratio.", "content": "Association between documented coronary artery disease and urinary albumin, albumin to creatinine ratio. The aim of this study was to investigate whether the amount of urinary albumin concentration (UAC) or urinary albumin to creatinine ratio (UACR) is more strongly associated with angiographically documented coronary artery disease (CAD). A total of 199 consecutive patients [11 9(60%) male, 80 (40%) female, mean age =57±10] undergoing diagnostic coronary angiography were included in the study. Significant coronary artery disease was defined as a stenosis equal to or above 50% in the main coronary artery or in one of the other branches. UAC and UACR were calculated from the urine. Baseline clinical parameters, UAC and UACR were compared between subjects with and without CAD. Factors predicting CAD were evaluated by multivariate analysis. Baseline clinical and laboratory characteristics of patients with and without CAD were not different except for a slightly male predominance in patients with CAD. Patients with CAD had significantly higher UACs and UACRs than patients without CAD (32.14±31.27 mg/day vs. 15.61±16.70 mg/day, p=0.01; 9.11±7.42 mg/g vs. 4.80±3.28 mg/g, p=0.009). A positive correlation was found between Gensini score and UACR (p=0.01), whereas no correlation was found between Gensini and UAC. UACR was the only significant parameter for the presence of CAD in the multivariate analysis adjusted for age, sex, other well known CAD risk factors, UAC and UACR. Our preliminary results suggest that UACR is more closely associated with angiography documented CAD than is the level of UAC itself, but UACR maybe more significantly associated with angiography documented CAD than with the levels of UAC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980959"}
{"pmid": "20980960", "title": "Platinum - sensitive relapsed epithelial ovarian cancer: not all the patients benefit from reinduction with carboplatin and paclitaxel.", "content": "Platinum - sensitive relapsed epithelial ovarian cancer: not all the patients benefit from reinduction with carboplatin and paclitaxel. It is widely accepted that patients with ovarian cancer relapsing 6 to 12 months after completion of a platinum-based regimen are considered to be partially platinum-sensitive. The aim of this study was to evaluate and correlate the efficacy and toxicity of reinduction with paclitaxel-carboplatin in a platinum-sensitive epithelial ovarian cancer patient cohort with previous platinum-free interval (PFI). We studied retrospectively 39 patients with platinum-sensitive epithelial ovarian cancer, who received primary chemotherapy at the Institute for Oncology and Radiology of Serbia, between January 2002 and May 2008. All patients were treated with paclitaxel and carboplatin for metastatic disease. Subsequent to progression, patients were re-treated with the same chemotherapy in group A (PFI 6-12 months) or group B (PFI ≥12 months). The number of patients in group A was 14, and in group B it was 25. Response rate to reinduction in group A was 36% (partial response, 36%; stable disease, 0%; progressive disease, 64%) and in group B was 68% (complete response, 60%; partial response, 8%; stable disease, 4%; progressive disease, 28%; P=.05). The median response duration of the patients in group A arm was 20 months, whereas it was 17 months for those in group B (P=.721). There were no significant differences in the toxicity profile between the 2 groups. In terms of objective response rate this study supports the reinduction of carboplatin and paclitaxel in patients with a prior PFI of at least 12 months only. To define the best approach and the optimal treatment of patients with partially platinum-sensitive disease more precisely, future studies should apply treatment-free interval as a stratification criterion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980960"}
{"pmid": "20980963", "title": "Ruptured sinus of Valsalva aneurysm in a child with Down syndrome: a rare cardiac anomaly.", "content": "Ruptured sinus of Valsalva aneurysm in a child with Down syndrome: a rare cardiac anomaly. As many as forty to fifty per cent of children with Down syndrome are born with a cardiac anomaly. Sinus of Valsalva aneurysm in this syndrome is extremely rare, only three previous reports, and of adult onset. An asymptomatic 9 and a half year boy with Down syndrome presented with a cardiac murmur at routine examination. Clinical examination, transthoracic and transesopahageal echocardiography revealed the presence of a ruptured sinus of Valsalva aneurysm from the non - coronary sinus protruding into the right atrium. The child underwent successful surgical repair with full recovery. This fourth case report of sinus of Valsalva aneurysm occurring in association with Down syndrome is the youngest to date. Physicians caring for Down syndrome patients ought to be aware of this late onset cardiac malformation. Serial echocardiographic assessment of the aortic sinus of Valsalva in these patients may offer early detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980963"}
{"pmid": "20980961", "title": "Hearing preservation in partial deafness treatment.", "content": "Hearing preservation in partial deafness treatment. Partial deafness (PD) is a condition in which hearing loss occurs in at least 1 frequency critical to speech understanding. Current options for partial deafness treatment (PDT) rely on preoperative hearing preservation, which, along with the use of different means of acoustic and electric stimulation, enable extending the indications for various assistive hearing devices. Possible solutions include acoustic methods only, the use of hearing aids or middle ear implants, electric complementation, and a combination of electric and acoustic stimulation. A total of 95 patients (63 adults, 32 children) with different types of PD were treated using selected types of electrodes and the optimal \"round window\" approach to the inner ear, with at least 36 months of observation. The extension of PDT indications created an opportunity for patients with different hearing impairments who obtained no benefit from a hearing aid and did not qualify for standard cochlear implant application. The authors' observations are based on the findings that preservation of preoperative hearing had been achieved in 97.1% of adult patients (8 years' observation) and in 100% of children (6 years' observation). Those results send the important message that PDT is feasible and effective. To allow comparison of PDT results from different studies, the authors developed the Skarzynski PDT classification system, which permits the comparison of postoperative results, including the degree of hearing preservation and, more importantly, the patient's understanding of speech after treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980961"}
{"pmid": "20980962", "title": "Immunosuppressive regimen and prevalence of chronic kidney disease in orthotopic heart transplant recipients.", "content": "Immunosuppressive regimen and prevalence of chronic kidney disease in orthotopic heart transplant recipients. Heart transplantation is an established treatment for advanced heart failure. Heart transplant recipients experience a number of complications related to pharmacological immunosuppression and infections. Chronic kidney disease (CKD) is an important long-term complication of all forms of organ transplantation other than renal. It has been shown that a GFR <60ml/min is predictive of premature cardiovascular death. The aim of our study was to assess kidney function in relation to the type of immunosuppression regimen used. We analyzed 169 patients who underwent their first orthotopic heart transplant. The immunosuppressive regimen of prevalent patients consisted of tacrolimus (n=60), cyclosporine (n=109), in combination with mycophenolate mofetil (n=134), azathioprine (n=4), everolimus (n=28) or sirolimus (n=8). GFR was estimated using 3 formulae: CKD-EPI, MDRD and the Cockcroft-Gault. Complete blood count, urea, serum lipids, fasting glucose, creatinine, and NT-proBNP were also analyzed. In patients treated with tacrolimus, we observed a higher eGFR (all formulae), a greater 24-hour creatinine clearance, and lower serum cholesterol, LDL-cholesterol and triglyceride values than in patients treated with cyclosporine. Patients treated with tacrolimus were younger than those treated with cyclosporine. However, the time elapsed after OHT was similar in both groups. The prevalence of CKD (eGFR <60 ml/min) in the tacrolimus-treated patients was 45%, whereas in the cyclosporine treated group it was 87% (p<0.01). The prevalence of CKD is high in heart transplant recipients. Tacrolimus-based immunosuppression was associated with better kidney function and more favorable lipid profile. Evaluation of renal function is important in order to select the appropriate strategy by individually tailored therapy to achieve the best possible outcomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980962"}
{"pmid": "20980964", "title": "Application of manuka honey and GENADYNE A4 negative pressure wound therapy system in a 55-year-old woman with extensive phlegmonous and necrotic lesions in the abdominal integuments and lumbar region after traumatic rupture of the colon.", "content": "Application of manuka honey and GENADYNE A4 negative pressure wound therapy system in a 55-year-old woman with extensive phlegmonous and necrotic lesions in the abdominal integuments and lumbar region after traumatic rupture of the colon. Antibiotic resistance of bacteria is on the rise and thus, the discovery of alternative therapeutic agents is urgently needed. Honey possesses good therapeutic potential, including wound healing properties and antimicrobial activity. The authors report on the case of a 55-year-old woman with extensive phlegmonous and necrotic lesions of the abdominal integuments and the lumbar area following traumatic colonic rupture, treated with Manuka honey wound dressings and the GENADYNE A4 negative pressure wound healing system. The application of the Manuka honey and the GENADYNE A4 negative pressure wound healing system in treating phlegmonous lesions of the abdominal integuments after rupture of the colon brought good effects, ultimately enabling skin autografting on the wound site and complete wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980964"}
{"pmid": "20980965", "title": "Stabilizing severely open fractures of the tibia with a surgical suture: an alternative and feasible method for osteosynthesis.", "content": "Stabilizing severely open fractures of the tibia with a surgical suture: an alternative and feasible method for osteosynthesis. Outcomes concerning treatment of severely open fractures of the tibia have achieved great success with the advent of powerful antibiotics, superb microsurgery techniques, and advanced stabilization instruments. However, severe pollution in the wound and high comminution of the fragments may restrict application of internal or external fixators. The condition could appear more complicated if osteoporosis and polytrauma are present or if those special instruments are unavailable. We tried using a surgical suture to stabilize severely open fractures of the tibia in the elderly with osteoporosis. A 65-year-old woman with a severely open fracture of the tibia was treated with a surgical suture, and the result was satisfactory in early period. We discuss the new but traditional osteosynthesis method. A surgical suture osteosynthesis could act as an additional alternative when special fractures or conditions occur. Postoperative results in early period are satisfactory. Long-term results and clinical experience should be analyzed and discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980965"}
{"pmid": "20980966", "title": "The biopsychosocial model, religion and a unified theory of diseases.", "content": "The biopsychosocial model, religion and a unified theory of diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980966"}
{"pmid": "20980968", "title": "The pulse arrival time approach for non-invasive hemodynamic monitoring in low-acuity settings.", "content": "The pulse arrival time approach for non-invasive hemodynamic monitoring in low-acuity settings. Hemodynamic monitoring in hospitalized patients is crucial since in clinical practice unexpected deterioration of cardiovascular function (e.g. pulmonary embolism resulting in syncope) remains a serious problem and an important cause of death. Standard pulse oximetrie in low acuity settings is nowadays predominately used to monitor peripheral oxygen saturation. Of note, there is evidence that additional analyses of pulse wave characteristics might be a valuable source of information to generate additional insights into the cardiorespiratory status of the patient. Herein, we present our initial experience using a hemodynamic surrogate measure called pulse arrival time (PAT) derived from standard photoplethysmography (PPG), single-lead electrocardiogram (ECG), and context information based on a small body-worn monitoring system for continuous unsupervised monitoring during short-term physical exercise and posture changes. This paper presents examples of using PPG signals for continuous non-invasive monitoring and discusses PAT and heart rate responses observed during short-term physical exercise, posture changes, and tilt table testing resulting in syncope. Our results indicate that hemodynamic adaptatations being detected by PPG and ECG analysis might be useful to monitor high-risk patients in low acuity settings. Context information on posture and physical activity is imperatively needed to interpret PAT monitoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980968"}
{"pmid": "20980969", "title": "Prevalence of psychoactive substances use in a Lithuanian women's prison revisited after 5 years.", "content": "Prevalence of psychoactive substances use in a Lithuanian women's prison revisited after 5 years. This paper re-examines the prevalence of psychoactive substances (tobacco, alcohol, narcotic drugs) use among inmates in a Lithuanian women's prison. The main goal of this study was to determinate the changes in the use of the psychoactive substances in a women's prison in Lithuania. We accomplished the retesting of the first ever investigation of this kind, carried out in 2004, using the same questionnaire, in the only women's prison in Lithuania. In June 2009, 71 (27.8%) women of 255 inmates of the prison were given questionnaires with information about the aim of the study, stating that the study was voluntary and anonymous, and obtaining permission for release of information. The results were compared with the previous investigation. A statistical analysis was carried out using SPSS 17.0. Tobacco smokers comprised 85.3% of respondents.; the average age at which respondents started to smoke was 14±7.3 years; 57.7% of respondents had tried narcotic drugs at least once; 22.5% of respondents used drugs (in 2004 we had found no drug use in this women's prison); 18.3% of respondents indicated that they narcotic drugs were tried for the first time away, 4.2% - in a custodial establishment. Psychoactive substances are often used due to their psychological effect. inmates constitute a high-risk group of drug users and distributors of narcotic drugs. Intravenous narcotics stimulating dangerous behavior prevail in Lithuanian prisons. Women in prison are especially prone to smoking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980969"}
{"pmid": "20980970", "title": "In utero surgery - current state of the art: part I.", "content": "In utero surgery - current state of the art: part I. Fetal surgery, also referred to as in utero, prenatal or intrauterine surgery, consists of treatment of congenital malformations during fetal period. The idea of treating malformations diagnosed in the course of intrauterine life dates back to 1963, when Lilly performed first blood transfusion in the fetus. Ever since then, it has been introduced as treatment option in series of lethal malformations. Efforts are being made to treat nonlethal malformations by means of fetal surgery. A comprehensive search of the literature using MEDLINE and PubMed between 1925 and February 2009 was performed. Search terms for MEDLINE and PubMed were: fetal surgery, foetal surgery, in utero surgery, prenatal surgery, and in utero treatment. In addition, information was obtained at Web sites of International Medicine and Surgery Society and the University of California Fetal Treatment Centre. Our attention focused on the overall view on fetal surgery history, its development and perspectives. Moreover, owing to the authors' interest in plastic surgery, some remarks on the role of intrauterine medicine and surgery in this branch of medicine were made. In utero surgery may be regarded as an efficient tool of preventive medicine. It offers some advantages that no other branch of medicine may offer. However, its implementation is more troublesome than it used to be regarded as before. Therefore only selected cases may benefit from its advantages. Nevertheless, current tendencies are to include, after thorough evaluation of benefit - risk ratio, some new indications for fetal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980970"}
{"pmid": "20980971", "title": "Influence of statins on effector and regulatory immune mechanisms and their potential clinical relevance in treating autoimmune disorders.", "content": "Influence of statins on effector and regulatory immune mechanisms and their potential clinical relevance in treating autoimmune disorders. Studies have shown that HMG-CoA reductase inhibitors possess anti-inflammatory properties, for example, decreasing serum levels of proinflammatory cytokines (e.g., TNF-α, IL-1β, and IL-6) or decreasing the activity of numerous effector mechanisms. However, they also may influence the immune system by affecting a wide range of regulatory actions, for example, Treg- and Th2-type response activation as well as Th1 and Th17 response diminishing. These features provide the rationale for potential application of statins in treating chronic inflammatory diseases and other disorders with the involvement of the immune system. This article seeks to review the immunomodulatory actions of statins and their possible implementation in treating rheumatoid arthritis, multiple sclerosis, and other autoimmune disorders in humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980971"}
{"pmid": "20980972", "title": "Future possibilities in glaucoma therapy.", "content": "Future possibilities in glaucoma therapy. Glaucoma is a group of eye diseases causing irreversible optic nerve damage. This review presents 4 elements of future glaucoma treatment strategies: baroprotection, vasoprotection, neuroprotection and gene therapy. New baroprotection includes compounds that alter the actin cytoskeleton (rho-kinase inhibitors, latrunculin, cytochalasin), new drugs that enhance aqueous outflow via the trabecular meshwork (statins, steroid antagonists) and via the uveoscleral route (EP2 agonists, 5-HT2 agonists), as well as new classes of components that suppress aqueous humor formation (cannabinoids). Vasoprotection includes blocking reperfusion injury (NOS-2 inhibitors, endothelin blockers, MMP-9 inhibitors). Concerning neuroprotection antiamyloids antibodies, erythropoietin and caspase inhibitors are discussed. Gene therapy may target various effectors: the trabecular meshwork (cytoskeleton regulatory proteins, miocyllin, MMPs), the ciliary body epithelium (genes modifying aqueous humor production, neuropeptides), the ciliary body cells (MMPs, genes of local PGs biosynthesis, ciliary muscle relaxants), the retinal ganglion cells (neurotrophin genes, anti-apoptotic genes), Müller cells (neurotrophins, GLAST) and conjunctiva (gene of chloramphenicol acetyltransferase, inhibitor p21). Experimental studies on the graft mesenchymal stem cells and mature retinal cells to replace the dead retinal ganglion cells are advanced. Immunotherapy, offering a vaccination, providing protection against loss of retinal ganglion cells, has been investigated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980972"}
{"pmid": "20980973", "title": "Targeting transcription factor Stat4 uncovers a role for interleukin-18 in the pathogenesis of severe lupus nephritis in mice.", "content": "Targeting transcription factor Stat4 uncovers a role for interleukin-18 in the pathogenesis of severe lupus nephritis in mice. Polymorphisms in the transcription factor Stat4 gene have been implicated as risk factors for systemic lupus erythematosus. Although some polymorphisms have a strong association with autoantibodies and nephritis, their impact on pathophysiology is still unknown. To explore this further we used signal transducers and activators of transcription 4 (Stat4) knockout MRL/MpJ-Fas(lpr)/Fas(lpr) (MRL-Fas(lpr)) mice and found that they did not differ in survival or renal function from Stat4-intact MRL-Fas(lpr) mice. Circulating interleukin (IL)-18 levels, however, were elevated in Stat4-deficient compared to Stat4-intact mice, suggesting that this interleukin might contribute to the progression of lupus nephritis independent of Stat4. In a second approach, Stat4 antisense or missense oligonucleotides or vehicle were given to MRL-Fas(lpr) mice with advanced nephritis. Each of these treatments temporarily ameliorated disease, although IL-18 was increased in each setting. Based on these findings, studies using gene transfer to overexpress IL-18 in MRL-Fas(lpr) and IL-12p40/IL-23 knockout MRL-Fas(lpr) mice reveal a critical role for IL-18 in mediating disease. Thus, the Stat4 and IL-12 (an activator of Stat4)-independent factor, IL-18, can drive autoimmune lupus nephritis in MRL-Fas(lpr) mice. Temporarily blocking Stat4 during advanced nephritis ameliorates disease, suggesting a time-dependent compensatory proinflammatory mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980973"}
{"pmid": "20980975", "title": "De novo development of circulating anti-endothelial cell antibodies rather than pre-existing antibodies is associated with post-transplant allograft rejection.", "content": "De novo development of circulating anti-endothelial cell antibodies rather than pre-existing antibodies is associated with post-transplant allograft rejection. Anti-endothelial cell antibodies (AECAs) are thought to be involved in the development of renal allograft rejection. To explore this further, we determine whether AECAs play a role both in predicting the incidence of allograft rejection and long-term outcomes by analysis of serum samples from 226 renal allograft recipients for AECAs pre- and post-transplant. Surprisingly, the presence of pre-existing AECAs was not associated with either an increased risk of rejection or a detrimental impact on recipient/graft survival. Subsequent de novo AECAs, however, were associated with a significantly increased risk of early acute rejection. Moreover, these rejections tended to be more severe with a significantly increased incidence of both steroid-resistant and multiple episodes of acute rejection. The acute rejections associated with de novo AECAs did not correlate with C4d deposition at the time of renal biopsy, but did demonstrate an association with the presence of glomerulitis and peritubular capillary inflammation. Significantly more patients with de novo AECAs developed graft dysfunction. Thus, our prospective study suggests the emergence of de novo AECAs is associated with transplant rejection that may lead to allograft dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980975"}
{"pmid": "20980974", "title": "Predicting idiopathic toxicity of cisplatin by a pharmacometabonomic approach.", "content": "Predicting idiopathic toxicity of cisplatin by a pharmacometabonomic approach. Cisplatin has been one of the most widely used anticancer agents, but its nephrotoxicity remains a dose-limiting complication. Here, we evaluated the idiopathic nature and the predose prediction of cisplatin-induced nephrotoxicity using a nuclear magnetic resonance (NMR)-based pharmacometabonomic approach. Cisplatin produced serious toxic responses in some animals (toxic group), but had little effect in others (nontoxic group), as judged by hematological and histological results. The individual metabolic profiles, assessed by urine NMR spectra, showed large differences between the post-administration profiles of the two groups, indicating the relevance of the NMR approach. Importantly, multivariate analysis of the NMR data showed that the toxic and nontoxic groups can be differentiated based on the pretreatment metabolite profiles. Leave-one-out analysis, performed to evaluate the practical performance of our approach, gave a 66% accuracy rate in predicting toxic responses based on the pretreatment metabolite profiles. Hence, we provide a working model that can explain the idiopathic toxicity mechanism based on marker metabolites found by NMR analysis consistent with tissue NADH measurements. Thus, a pharmacometabonomic approach using pretreatment metabolite profiles may help expedite personalized chemotherapy of anticancer drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980974"}
{"pmid": "20980976", "title": "Urinary levels of regenerating islet-derived protein III β and gelsolin differentiate gentamicin from cisplatin-induced acute kidney injury in rats.", "content": "Urinary levels of regenerating islet-derived protein III β and gelsolin differentiate gentamicin from cisplatin-induced acute kidney injury in rats. A key aspect for the clinical handling of acute kidney injury is an early diagnosis, for which a new generation of urine biomarkers is currently under development including kidney injury molecule 1 and neutrophil gelatinase-associated lipocalin. A further diagnostic refinement is needed where one specific cause among several potentially nephrotoxic insults can be identified during the administration of multidrug therapies. In this study we identified increases in regenerating islet-derived protein III beta (reg IIIb) and gelsolin as potential differential urinary markers of gentamicin's nephrotoxicity. Indeed, urinary levels of both reg IIIb and gelsolin distinguish between the nephrotoxicity caused by gentamicin from that caused by cisplatin where these markers were not increased by the latter. Reg IIIb was found to be overexpressed in the kidneys of gentamicin-treated rats and excreted into the urine, whereas urinary gelsolin originated from the blood by glomerular filtration. Our results illustrate an etiological diagnosis of acute kidney injury through analysis of urine. Thus, our results raise the possibility of identifying the actual nephrotoxin in critically ill patients who are often treated with several nephrotoxic agents at the same time, thereby providing the potential for tailoring therapy to an individual patient, which is the aim of personalized medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980976"}
{"pmid": "20980977", "title": "Changes in dietary protein intake has no effect on serum cystatin C levels independent of the glomerular filtration rate.", "content": "Changes in dietary protein intake has no effect on serum cystatin C levels independent of the glomerular filtration rate. Cystatin C is being considered as a replacement for serum creatinine in the estimation of the glomerular filtration rate (GFR); however, its plasma levels might be affected by factors other than the GFR, such as protein intake. We performed a post hoc analysis of the data in the Modification of Diet in Renal Disease study, in which we compared serum creatinine and cystatin C levels in 741 patients with available estimates of protein intake at baseline prior to their randomization to diets containing various amounts of protein, and at 2 years of follow-up in 426 of these patients in whom a cystatin C measurement was available. The 503 patients in study A (GFR 25-55 ml/min per 1.73 m(2)) had been assigned a low (0.58 g/kg per day) or a usual (1.3 g/kg per day) protein intake, and the 238 participants in study B (GFR 13-24 ml/min per 1.73 m(2)) were assigned a very low (0.28 g/kg per day) or the low protein intake. In either study group, lowering the dietary protein intake reduced the change in creatinine, but did not have a significant change in cystatin C. Thus, in patients with moderate-to-severe chronic kidney disease, serum cystatin C unlike serum creatinine was not affected by dietary protein intake independent of changes in GFR. Hence, cystatin C may allow more accurate estimates of GFR than creatinine for patients with reduced protein intake. Further study of other non-GFR determinants of cystatin C is needed before the widespread adoption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980977"}
{"pmid": "20980979", "title": "Discussing standards.", "content": "Discussing standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980979"}
{"pmid": "20980980", "title": "The Archon Genomics X PRIZE for whole human genome sequencing.", "content": "The Archon Genomics X PRIZE for whole human genome sequencing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980980"}
{"pmid": "20980978", "title": "Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-β-D-glucosaminidase.", "content": "Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-β-D-glucosaminidase. Elevated urinary albumin excretion in patients with type 1 diabetes reverts to normoalbuminuria in a majority of patients but advances toward proteinuria in some. In order to gain valuable insights into the early pathophysiology of diabetic nephropathy we evaluated the association of kidney tubular injury biomarkers with changes in albuminuria in patients with type 1 diabetes mellitus. Urine levels of kidney injury molecule-1 (KIM-1), N-acetyl-β-D-glucosaminidase (NAG), and some inflammatory markers were determined in 38 healthy individuals and 659 patients with type 1 diabetes mellitus having varying degrees of albuminuria. Urinary interleukin-6, CXCL10/IP-10, NAG, and KIM-1 levels were very low in healthy individuals, increased in type 1 patients with normoalbuminuria, and were highest in diabetic patients that had microalbuminuria. Low baseline concentrations of urinary KIM-1 and NAG both individually and collectively were significantly associated with the regression of microalbuminuria over the subsequent 2 years; an effect independent of clinical characteristics. Progression and regression of microalbuminuria were unrelated to urinary levels of interleukins 6 and 8, CXCL10/IP-10, and monocyte chemoattractant protein-1. Thus our results show that lower urinary KIM-1 and NAG levels were associated with the regression of microalbuminuria in type 1 diabetes mellitus. Hence, tubular dysfunction is a critical component of the early course of diabetic nephropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980978"}
{"pmid": "20980981", "title": "No evidence for lateral gene transfer between salmonids and schistosomes.", "content": "No evidence for lateral gene transfer between salmonids and schistosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980981"}
{"pmid": "20980982", "title": "Marker papers and data citation.", "content": "Marker papers and data citation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980982"}
{"pmid": "20980983", "title": "Lack of evidence for DNA methylation of Invader4 retroelements in Drosophila and implications for Dnmt2-mediated epigenetic regulation.", "content": "Lack of evidence for DNA methylation of Invader4 retroelements in Drosophila and implications for Dnmt2-mediated epigenetic regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980983"}
{"pmid": "20980985", "title": "A common mechanism for microcephaly.", "content": "A common mechanism for microcephaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980985"}
{"pmid": "20980986", "title": "Glutamate receptors and learning and memory.", "content": "Glutamate receptors and learning and memory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980986"}
{"pmid": "20980987", "title": "Genome-wide association studies coming of age in rice.", "content": "Genome-wide association studies coming of age in rice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980987"}
{"pmid": "20980989", "title": "High-novelty-preference rats are predisposed to compulsive cocaine self-administration.", "content": "High-novelty-preference rats are predisposed to compulsive cocaine self-administration. Sensation/novelty-seeking is amongst the best markers of cocaine addiction in humans. However, its implication in the vulnerability to cocaine addiction is still a matter of debate, as it is unclear whether this trait precedes or follows the development of addiction. Sensation/novelty-seeking trait has been identified in rats on the basis of either novelty-induced locomotor activity (high-responder (HR) trait) or novelty-induced place preference (high-novelty-preference trait (HNP)). HR and HNP traits have been associated with differential sensitivity to psychostimulants. However, it has recently been demonstrated that HR rats do not develop compulsive cocaine self-administration (SA) after protracted exposure to the drug, thereby suggesting that at least one dimension of sensation/novelty seeking in the rat is dissociable from the vulnerability to switch from controlled to compulsive cocaine SA. We therefore investigated whether HNP, as measured as the propensity to choose a new environment in a free choice procedure, as opposed to novelty-induced locomotor activity, predicts the vulnerability to, and the severity of, addiction-like behavior for cocaine. For this, we identified HR/LR rats and HNP/LNP rats before any exposure to cocaine. After 60 days of cocaine SA, each rat was given an addiction score based on three addiction-like behaviors (persistence of responding when the drug is signaled as not available, high breakpoint under progressive ratio schedule and resistance to punishment) that resemble the clinical features of drug addiction, namely inability to refrain from drug seeking, high motivation for the drug and compulsive drug use despite adverse consequences. We show that, as opposed to HR rats, HNP rats represent a sub-population predisposed to compulsive cocaine intake, displaying higher addiction scores than LNP rats. This study thereby provides new insights into the factors predisposing to cocaine addiction, supporting the hypothesis that addiction is sustained by two vulnerable phenotypes: a 'drug use prone' phenotype such as HR which brings an individual to develop drug use and an 'addiction prone' phenotype, such as HNP, which facilitates the shift from sustained to compulsive drug intake and addiction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980989"}
{"pmid": "20980991", "title": "Efficacy of antimanic treatments: meta-analysis of randomized, controlled trials.", "content": "Efficacy of antimanic treatments: meta-analysis of randomized, controlled trials. We conducted meta-analyses of findings from randomized, placebo-controlled, short-term trials for acute mania in manic or mixed states of DSM (III-IV) bipolar I disorder in 56 drug-placebo comparisons of 17 agents from 38 studies involving 10,800 patients. Of drugs tested, 13 (76%) were more effective than placebo: aripiprazole, asenapine, carbamazepine, cariprazine, haloperidol, lithium, olanzapine, paliperdone, quetiapine, risperidone, tamoxifen, valproate, and ziprasidone. Their pooled effect size for mania improvement (Hedges' g in 48 trials) was 0.42 (confidence interval (CI): 0.36-0.48); pooled responder risk ratio (46 trials) was 1.52 (CI: 1.42-1.62); responder rate difference (RD) was 17% (drug: 48%, placebo: 31%), yielding an estimated number-needed-to-treat of 6 (all p<0.0001). In several direct comparisons, responses to various antipsychotics were somewhat greater or more rapid than lithium, valproate, or carbamazepine; lithium did not differ from valproate, nor did second generation antipsychotics differ from haloperidol. Meta-regression associated higher study site counts, as well as subject number with greater placebo (not drug) response; and higher baseline mania score with greater drug (not placebo) response. Most effective agents had moderate effect-sizes (Hedges' g=0.26-0.46); limited data indicated large effect sizes (Hedges' g=0.51-2.32) for: carbamazepine, cariprazine, haloperidol, risperidone, and tamoxifen. The findings support the efficacy of most clinically used antimanic treatments, but encourage more head-to-head studies and development of agents with even greater efficacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980991"}
{"pmid": "20980992", "title": "The subjective, reinforcing, and analgesic effects of oxycodone in patients with chronic, non-malignant pain who are maintained on sublingual buprenorphine/naloxone.", "content": "The subjective, reinforcing, and analgesic effects of oxycodone in patients with chronic, non-malignant pain who are maintained on sublingual buprenorphine/naloxone. Some sources suggest that significant misuse of opioid drugs exists among patients with chronic pain. However, the risk factors and motivation behind their abuse may differ from those of other opioid abusers. This study sought to examine the abuse liability of oxycodone among patients with chronic, non-malignant pain who met the DSM-IV criteria for opioid abuse. Eighteen opioid-dependent patients with chronic pain lived on an in-patient unit of the New York State Psychiatric Institute during the 7-week study. Participants were given oral oxycodone (0, 10, 20, 40, and 60 mg/70 kg) while maintained on various doses of sublingual buprenorphine/naloxone (Bup/Nx; 2/0.5, 8/2, and 16/4 mg/day). Doses of both medications were administered under double-blind conditions. Oxycodone produced an overall positive, but less robust, subjective profile than previously reported in recreational opioid users without pain. Furthermore, unlike our findings in recreational opioid users and more similar to effects in non-drug-abusing individuals, oxycodone failed to serve as a reinforcer. As for the maintenance drug, Bup/Nx produced a dose-related reduction in some of the effects of acutely administered oxycodone. These data suggest that sublingual Bup/Nx has the potential as an analgesic medication and further research should investigate its use in treating patients with chronic pain who abuse opioids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980992"}
{"pmid": "20980990", "title": "Serotonin and dopamine play complementary roles in gambling to recover losses.", "content": "Serotonin and dopamine play complementary roles in gambling to recover losses. Continued gambling to recover losses--'loss chasing'--is a prominent feature of social and pathological gambling. However, little is known about the neuromodulators that influence this behavior. In three separate experiments, we investigated the role of serotonin activity, D(2)/D(3) receptor activity, and beta-adrenoceptor activity on the loss chasing of age and IQ-matched healthy adults randomized to treatment or an appropriate control/placebo. In Experiment 1, participants consumed amino-acid drinks that did or did not contain the serotonin precursor, tryptophan. In Experiment 2, participants received a single 176 μg dose of the D(2)/D(3) receptor agonist, pramipexole, or placebo. In Experiment 3, participants received a single 80 mg dose of the beta-adrenoceptor blocker, propranolol, or placebo. Following treatment, participants completed a computerized loss-chasing game. Mood and heart rate were measured at baseline and following treatment. Tryptophan depletion significantly reduced the number of decisions made to chase losses, and the number of consecutive decisions to chase, in the absence of marked changes in mood. By contrast, pramipexole significantly increased the value of losses chased and diminished the value of losses surrendered. Propranolol markedly reduced heart rate, but produced no significant changes in loss-chasing behavior. Loss chasing can be thought of as an aversively motivated escape behavior controlled, in part, by the marginal value of continued gambling relative to the value of already accumulated losses. Serotonin and dopamine appear to play dissociable roles in the tendency of individuals to gamble to recover, or to seek to 'escape' from, previous losses. Serotonergic activity seems to promote the availability of loss chasing as a behavioral option, whereas D(2)/D(3) receptor activity produces complex changes in the value of losses judged worth chasing. Sympathetic arousal, at least as mediated by beta-adrenoceptors, does not play a major role in laboratory-based loss-chasing choices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980990"}
{"pmid": "20980993", "title": "A dopamine D1 receptor-dependent β-arrestin signaling complex potentially regulates morphine-induced psychomotor activation but not reward in mice.", "content": "A dopamine D1 receptor-dependent β-arrestin signaling complex potentially regulates morphine-induced psychomotor activation but not reward in mice. Morphine is a widely used analgesic in humans that is associated with multiple untoward effects, such as addiction and physical dependence. In rodent models, morphine also induces locomotor activity. These effects likely involve functionally selective mechanisms. Indeed, G protein-coupled receptor desensitization and adaptor protein β-arrestin 2 (βarr2) through its interaction with the μ-opioid receptor regulates the analgesic but not the rewarding properties of morphine. However, βarr2 is also required for morphine-induced locomotor activity in mice, but the exact cellular and molecular mechanisms that mediate this arrestin-dependent behavior are not understood. In this study, we show that βarr2 is required for morphine-induced locomotor activity in a dopamine D1 receptor (D1R)-dependent manner and that a βarr2/phospho-ERK (βarr2/pERK) signaling complex may mediate this behavior. Systemic administration of SL327, an MEK inhibitor, inhibits morphine-induced locomotion in wild-type mice in a dose-dependent manner. Acute morphine administration to mice promotes the formation of a βarr2/pERK signaling complex. Morphine-induced locomotor activity and formation of the βarr2/pERK signaling complex is blunted in D1R knockout (D1-KO) mice and is presumably independent of D2 dopamine receptors. However, D1Rs are not required for morphine-induced reward as D1-KO mice show the same conditioned place preference for morphine as do control mice. Taken together, these results suggest a potential role for a D1R-dependent βarr2/pERK signaling complex in selectively mediating the locomotor-stimulating but not the rewarding properties of morphine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980993"}
{"pmid": "20980997", "title": "Correlation between imatinib pharmacokinetics and clinical response in Japanese patients with chronic-phase chronic myeloid leukemia.", "content": "Correlation between imatinib pharmacokinetics and clinical response in Japanese patients with chronic-phase chronic myeloid leukemia. Despite the outstanding results generally obtained with imatinib mesylate (IM) in the treatment of chronic myeloid leukemia (CML), some patients show a poor molecular response. To evaluate the relationship between steady-state trough plasma IM concentration (IM-C(min)) and clinical response in CML patients, we integrated data from six independent Japanese studies. Among 254 CML patients, the mean IM-C(min) was 1,010.5 ng/ml. Importantly, IM-C(min) was significantly higher in patients who achieved a major molecular response (MMR) than in those who did not (P = 0.002). Multivariate analysis showed that an MMR was associated with both age (odds ratio (OR) = 0.97 (0.958-0.995); P = 0.0153) and with IM-C(min) (OR = 1.0008 (1.0003-1.0015); P = 0.0044). Given that patients with IM-C(min) values >1,002 ng/ml had a higher probability of achieving an MMR in our large cohort (P = 0.0120), the data suggest that monitoring of IM levels in plasma may improve the efficacy of IM therapy for CML patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980997"}
{"pmid": "20980996", "title": "Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes.", "content": "Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes. Innate immune recognition of the bacterial cell wall constituent peptidoglycan by the cytosolic nucleotide-binding oligomerization domain 2 (Nod2) receptor has a pivotal role in the maintenance of intestinal mucosal homeostasis. Whereas peptidoglycan cleavage by gut-derived lysozyme preserves the recognition motif, the N-acetylmuramoyl-L-alanine amidase activity of the peptidoglycan recognition protein 2 (PGLYRP-2) destroys the Nod2-detected muramyl dipeptide structure. PGLYRP-2 green fluorescent protein (GFP) reporter and wild-type mice were studied by flow cytometry and quantitative RT-PCR to identify Pglyrp-2 expression in cells of the intestinal mucosa and reveal a potential regulatory function on epithelial peptidoglycan recognition. CD3(+)/CD11c(+) T lymphocytes revealed significant Pglyrp-2 expression, whereas epithelial cells and intestinal myeloid cells were negative. The mucosal Pglyrp-2-expressing lymphocyte population demonstrated a mixed T-cell receptor (TCR) αβ or γδ phenotype with predominant CD8α and less so CD8β expression, as well as significant staining for the activation markers B220 and CD69, presenting a typical intraepithelial lymphocyte phenotype. Importantly, exposure of peptidoglycan to PGLYRP-2 significantly reduced Nod2/Rip2-mediated epithelial activation. Also, moderate but significant alterations of the intestinal microbiota composition were noted in Pglyrp-2-deficient animals. PGLYRP-2 might thus have a significant role in regulation of the enteric host-microbe homeostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980996"}
{"pmid": "20980998", "title": "Twice-weekly administration of kisspeptin-54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea.", "content": "Twice-weekly administration of kisspeptin-54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea. Kisspeptin is a novel therapeutic target for infertility. A single kisspeptin-54 (KP-54) injection acutely stimulates the release of reproductive hormones in women with hypothalamic amenorrhea (HA), a commonly occurring condition characterized by absence of menstruation; however, twice-daily administration of KP-54 results in tachyphylaxis. We determined the time course of desensitization to twice-daily KP-54 injections, compared the effects of twice-daily and twice-weekly administration regimens of KP-54, and studied the effects of long-term twice-weekly administration of KP-54 on the release of reproductive hormones in women with HA. When KP-54 was administered twice daily, responsiveness to luteinizing hormone (LH) diminished gradually, whereas responsiveness to follicle-stimulating hormone (FSH) was nearly abolished by day 2. Twice-weekly KP-54 administration resulted in only partial desensitization, in contrast to the complete tolerance achieved with twice-daily administration. Women with HA who were treated with twice-weekly KP-54 injections had significantly elevated levels of reproductive hormones after 8 weeks as compared with treatment with saline. No adverse effects were observed. This study provides novel pharmacological data on the effects of KP-54 on the release of reproductive hormones in women with HA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980998"}
{"pmid": "20980999", "title": "A phase I study of the pharmacokinetic and safety profiles of oral pazopanib with a high-fat or low-fat meal in patients with advanced solid tumors.", "content": "A phase I study of the pharmacokinetic and safety profiles of oral pazopanib with a high-fat or low-fat meal in patients with advanced solid tumors. Pazopanib is an oral angiogenesis inhibitor of vascular endothelial growth factor (VEGF) receptor, platelet-derived growth factor receptor, and cytokine receptor. This open-label, randomized, crossover, phase I study evaluated the effect of low- and high-fat meals on the pharmacokinetics (PK) of pazopanib in patients with advanced solid tumors. Patients participated in either the lead-in cohort or randomized food-effect cohort. Patients in the lead-in cohort were administered a single dose of pazopanib 400 mg with a high-fat meal. Patients in the food-effect cohort were randomized to receive single doses of pazopanib 800 mg in fed condition (high- or low-fat meal) or fasting condition, in random sequence 14 days apart. After completion of the study, patients were given the opportunity to continue treatment with daily pazopanib 800 mg. Administration of pazopanib with both low- and high-fat meals increased maximum observed plasma concentration (C(max)) and area under the plasma concentration-time curve (AUC) by approximately twofold as compared with the corresponding values when administered to patients in the fasted condition. Therefore, pazopanib should be administered to patients in the fasted state so as to minimize within- and between-day variability in the systemic exposure to pazopanib in patients with cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980999"}
{"pmid": "20980995", "title": "The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation.", "content": "The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation. The tumor necrosis factor (TNF)-family cytokine TL1A (TNFSF15) costimulates T cells through its receptor DR3 (TNFRSF25) and is required for autoimmune pathology driven by diverse T-cell subsets. TL1A has been linked to human inflammatory bowel disease (IBD), but its pathogenic role is not known. We generated transgenic mice that constitutively express TL1A in T cells or dendritic cells. These mice spontaneously develop IL-13-dependent inflammatory small bowel pathology that strikingly resembles the intestinal response to nematode infections. These changes were dependent on the presence of a polyclonal T-cell receptor (TCR) repertoire, suggesting that they are driven by components in the intestinal flora. Forkhead box P3 (FoxP3)-positive regulatory T cells (Tregs) were present in increased numbers despite the fact that TL1A suppresses the generation of inducible Tregs. Finally, blocking TL1A-DR3 interactions abrogates 2,4,6 trinitrobenzenesulfonic acid (TNBS) colitis, indicating that these interactions influence other causes of intestinal inflammation as well. These results establish a novel link between TL1A and interleukin 13 (IL-13) responses that results in small intestinal inflammation, and also establish that TL1A-DR3 interactions are necessary and sufficient for T cell-dependent IBD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980995"}
{"pmid": "20981000", "title": "Acute alertness-promoting effects of a novel histamine subtype-3 receptor inverse agonist in healthy sleep-deprived male volunteers.", "content": "Acute alertness-promoting effects of a novel histamine subtype-3 receptor inverse agonist in healthy sleep-deprived male volunteers. The alertness-promoting effect of MK-0249 (10 or 50 mg), a histamine subtype-3 receptor (HRH3) inverse agonist (IA), was evaluated in the stimulant reference sleep deprivation model (SRSDM) using a double-blind, double-dummy, placebo- and modafinil- (200 mg) controlled, four-period crossover design in 24 healthy young men. The two primary hypotheses were related to sleep latency (first appearance of one epoch of stage 2, 3, or 4 or REM sleep, as detected using polysomnography (PSG)) at 8:00 AM on day 2. Statistically significant increases in sleep latency were observed in association with the use of modafinil 200 mg (9.07 min; P < 0.0001), MK-0249 50 mg (5.17 min; P = 0.008), and MK-0249 10 mg (5.45 min; P = 0.005) at the maintenance of wakefulness test (MWT) at 8:00 AM. Sleep latency was higher when averaged over all MWT time points (P < 0.0001 for modafinil and for both doses of MK-0249). The alertness-promoting effect with the use of MK-0249 in the SRSDM suggests that HRH3 IAs may be effective in disorders involving excessive somnolence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981000"}
{"pmid": "20980994", "title": "Short-term adaptation of conditioned fear responses through endocannabinoid signaling in the central amygdala.", "content": "Short-term adaptation of conditioned fear responses through endocannabinoid signaling in the central amygdala. The cannabinoid receptor type 1 (CB1) and the central nucleus of the amygdala (CeA) are both known to have crucial roles in the processing of fear and anxiety, whereby they appear to be especially involved in the control of fear states. However, in contrast to many other brain regions including the cortical subregions of the amygdala, the existence of CB1 in the CeA remains enigmatic. In this study we show that CB1 is expressed in the CeA of mice and that CB1 in the CeA mediates short-term synaptic plasticity, namely depolarization-induced suppression of excitation (DSE) and inhibition (DSI). Moreover, the CB1 antagonist AM251 increased both excitatory and inhibitory postsynaptic responses in CeA neurons. Local application of AM251 in the CeA in vivo resulted in an acutely increased fear response in an auditory fear conditioning paradigm. Upon application of AM251 in the basolateral nucleus of the amygdala (BLA) in an otherwise identical protocol, no such acute behavioral effects were detected, but CB1 blockade resulted in increased fear responses during tone exposures on the subsequent days. Moreover, we observed that the efficacy of DSE and DSI in the CeA was increased on the day following fear conditioning, indicating that a single tone-shock pairing resulted in changes in endocannabinoid signaling in the CeA. Taken together, our data show the existence of CB1 proteins in the CeA, and their critical role for ensuring short-term adaptation of responses to fearful events, thereby suggesting a potential therapeutic target to accompany habituation-based therapies of post-traumatic symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20980994"}
{"pmid": "20981001", "title": "Endoxifen, a new cornerstone of breast cancer therapy: demonstration of safety, tolerability, and systemic bioavailability in healthy human subjects.", "content": "Endoxifen, a new cornerstone of breast cancer therapy: demonstration of safety, tolerability, and systemic bioavailability in healthy human subjects. Endoxifen is an active metabolite of tamoxifen, a drug used in the treatment of breast cancer. In order to be clinically effective, tamoxifen must be converted to endoxifen by cytochrome P450 2D6 (CYP2D6). A study involving single escalating oral doses was conducted in humans to evaluate the safety, tolerability, and pharmacokinetics (PK) of endoxifen. This is the first study demonstrating that single oral doses of endoxifen are safe and well tolerated and have sufficient bioavailability to reach systemically effective levels in human subjects. Furthermore, it was found that endoxifen is rapidly absorbed and systemically available and that it displays dose proportionality in peak drug concentrations in plasma (C(max)) and area under the concentration-time curve extrapolated from 0 to ∞ (AUC(0-∞)) over the dose range 0.5-4.0 mg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981001"}
{"pmid": "20981003", "title": "Accelerator mass spectrometry measurement of intracellular concentrations of active drug metabolites in human target cells in vivo.", "content": "Accelerator mass spectrometry measurement of intracellular concentrations of active drug metabolites in human target cells in vivo. Accelerator mass spectrometry (AMS) is an ultrasensitive technique to detect radiolabeled compounds. We administered a microdose (100 µg) of (14)C-labeled zidovudine (ZDV) with or without a standard unlabeled dose (300 mg) to healthy volunteers. Intracellular ZDV-triphosphate (ZDV-TP) concentration was measured using AMS and liquid chromatography-tandem mass spectrometry (LC/MS/MS). AMS analysis yielded excellent concordance with LC/MS/MS and was 30,000-fold more sensitive. The kinetics of intracellular ZDV-TP formation changed several-fold over the dose range studied (100 µg-300 mg). AMS holds promise as a tool for quantifying intracellular drug metabolites and other biomediators in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981003"}
{"pmid": "20981002", "title": "Breaking barriers in the genomics and pharmacogenetics of drug addiction.", "content": "Breaking barriers in the genomics and pharmacogenetics of drug addiction. Drug addiction remains a substantial health issue with limited treatment options currently available. Despite considerable advances in the understanding of human genetic architecture, the genetic underpinning of complex disorders remains elusive. On the basis of our current understanding of neurobiology, numerous candidate genes have been implicated in the etiology and response to treatment for different addictions. Genome-wide association (GWA) studies have also identified novel targets. However, replication of these studies is often lacking, and this complicates interpretation. The situation is expected to improve as issues such as phenotypic characterization, the apparent \"missing heritability,\" the identification of functional variants, and possible gene-environment (G × E) interactions are addressed. In addition, there is growing evidence that genetic information can be useful in refining the choice of addiction treatment. As genetic testing becomes more common in the practice of medicine, a variety of ethical and practical challenges, some of which are unique to drug addiction, will also need to be considered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981002"}
{"pmid": "20981004", "title": "Developing pharmacogenetic evidence throughout clinical development.", "content": "Developing pharmacogenetic evidence throughout clinical development. Genetics as a discipline is fundamental for the pharmaceutical industry; it contributes to all therapeutic areas and has an impact throughout the research and development continuum, right up to and including clinical practice. Pharmacogenetics is seen as a significant contributor to increasing the efficiency and effectiveness of pharmaceutical R&D, and it enhances the growing interest in personalized medicine. This article discusses some contemporary issues that influence drug development and examines the potential of pharmacogenetics to reduce the risk and uncertainty that are inherent in the drug development process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981004"}
{"pmid": "20981005", "title": "Assessing the clinical utility of diagnostics used in drug therapy.", "content": "Assessing the clinical utility of diagnostics used in drug therapy. There is an ongoing debate over the evidentiary standards that should be applied for introduction of new diagnostics into routine clinical practice. Many call for evidence of \"clinical utility,\" i.e., a positive impact on patient outcomes. A diagnostic, when used with a medicine, has clinical utility if it improves the outcomes of drug therapy. Improved outcomes may be defined broadly, including benefits, harm reduction, and patient-reported outcomes. Much of the controversy centers around the methods of demonstrating clinical utility. For instance, are randomized prospective trials the only acceptable source of data? Practically speaking, many sources of evidence-mechanistic, pharmacologic, and observational-can contribute to a finding of clinical utility, depending on the circumstances. Clinical utility is highly indication specific, and achieving it is dependent on good analytical and diagnostic test performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981005"}
{"pmid": "20981006", "title": "Acceptance of biomarker-based tests for application in clinical practice: criteria and obstacles.", "content": "Acceptance of biomarker-based tests for application in clinical practice: criteria and obstacles. The journey from the discovery of a biomarker to its implementation in clinical practice is long and complex. There are many obstacles along the way, including lack of consistent evidence, inadequate validation of the biomarker, inadequate evidence of clinical utility, operational barriers to clinical implementation, and inadequate evidence of operational effectiveness or impact in clinical care. Multipronged approaches, incorporating input from many disciplines working together, will be required to overcome the obstacles to the clinical implementation and to allow the progression of clinical practice from the current paradigm of a one-size-fits-all strategy to more personalized treatment pathways that are more predictable in terms of health gains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981006"}
{"pmid": "20981008", "title": "Quantum tunnelling of the magnetization in a monolayer of oriented single-molecule magnets.", "content": "Quantum tunnelling of the magnetization in a monolayer of oriented single-molecule magnets. A fundamental step towards atomic- or molecular-scale spintronic devices has recently been made by demonstrating that the spin of an individual atom deposited on a surface, or of a small paramagnetic molecule embedded in a nanojunction, can be externally controlled. An appealing next step is the extension of such a capability to the field of information storage, by taking advantage of the magnetic bistability and rich quantum behaviour of single-molecule magnets (SMMs). Recently, a proof of concept that the magnetic memory effect is retained when SMMs are chemically anchored to a metallic surface was provided. However, control of the nanoscale organization of these complex systems is required for SMMs to be integrated into molecular spintronic devices. Here we show that a preferential orientation of Fe(4) complexes on a gold surface can be achieved by chemical tailoring. As a result, the most striking quantum feature of SMMs-their stepped hysteresis loop, which results from resonant quantum tunnelling of the magnetization-can be clearly detected using synchrotron-based spectroscopic techniques. With the aid of multiple theoretical approaches, we relate the angular dependence of the quantum tunnelling resonances to the adsorption geometry, and demonstrate that molecules predominantly lie with their easy axes close to the surface normal. Our findings prove that the quantum spin dynamics can be observed in SMMs chemically grafted to surfaces, and offer a tool to reveal the organization of matter at the nanoscale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981008"}
{"pmid": "20981009", "title": "Climate-driven population divergence in sex-determining systems.", "content": "Climate-driven population divergence in sex-determining systems. Sex determination is a fundamental biological process, yet its mechanisms are remarkably diverse. In vertebrates, sex can be determined by inherited genetic factors or by the temperature experienced during embryonic development. However, the evolutionary causes of this diversity remain unknown. Here we show that live-bearing lizards at different climatic extremes of the species' distribution differ in their sex-determining mechanisms, with temperature-dependent sex determination in lowlands and genotypic sex determination in highlands. A theoretical model parameterized with field data accurately predicts this divergence in sex-determining systems and the consequence thereof for variation in cohort sex ratios among years. Furthermore, we show that divergent natural selection on sex determination across altitudes is caused by climatic effects on lizard life history and variation in the magnitude of between-year temperature fluctuations. Our results establish an adaptive explanation for intra-specific divergence in sex-determining systems driven by phenotypic plasticity and ecological selection, thereby providing a unifying framework for integrating the developmental, ecological and evolutionary basis for variation in vertebrate sex determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981009"}
{"pmid": "20981007", "title": "Promoter polymorphisms in the β-2 adrenergic receptor are associated with drug-induced gene expression changes and response in acute lymphoblastic leukemia.", "content": "Promoter polymorphisms in the β-2 adrenergic receptor are associated with drug-induced gene expression changes and response in acute lymphoblastic leukemia. We investigated whether genetic polymorphisms in the promoter region of the proapoptotic β-2 adrenergic receptor gene (ADRB2) influence treatment-induced changes in ADRB2 expression in leukemia cells and response to chemotherapy. The ADRB2 promoter region was genotyped in germline DNA from 369 children with acute lymphoblastic leukemia (ALL). For 95 of the patients, sufficient RNA was available before and after in vivo treatment to assess treatment-induced gene expression changes in ALL cells. After treatment, the median ADRB2 mRNA expression was ninefold lower in leukemia cells of patients who ultimately relapsed as compared with patients who remained in continuous complete remission (CCR). Polymorphisms in the ADRB2 promoter were significantly linked to methotrexate (MTX)-induced upregulation in ADRB2 gene expression in ALL cells. Moreover, the ADRB2 promoter haplotype was significantly related to early treatment response in 245 children with ALL who received uniform treatment. We conclude that germline polymorphisms in ADRB2 are linked to the antileukemic effects of ALL chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981007"}
{"pmid": "20981011", "title": "Unveiling thermal transitions of polymers in subnanometre pores.", "content": "Unveiling thermal transitions of polymers in subnanometre pores. The thermal transitions of confined polymers are important for the application of polymers in molecular scale devices and advanced nanotechnology. However, thermal transitions of ultrathin polymer assemblies confined in subnanometre spaces are poorly understood. In this study, we show that incorporation of polyethylene glycol (PEG) into nanochannels of porous coordination polymers (PCPs) enabled observation of thermal transitions of the chain assemblies by differential scanning calorimetry. The pore size and surface functionality of PCPs can be tailored to study the transition behaviour of confined polymers. The transition temperature of PEG in PCPs was determined by manipulating the pore size and the pore-polymer interactions. It is also striking that the transition temperature of the confined PEG decreased as the molecular weight of PEG increased.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981011"}
{"pmid": "20981012", "title": "A systems approach towards the stoichiometry-controlled hetero-assembly of nanoparticles.", "content": "A systems approach towards the stoichiometry-controlled hetero-assembly of nanoparticles. A central theme in nanotechnology is to advance the fundamental understanding of nanoscale component assembly, thereby allowing rational structural design that may lead to materials with novel properties and functions. Nanoparticles (NPs) are often regarded as 'artificial atoms', but their 'reactions' are not readily controllable. Here, we demonstrate a complete nanoreaction system whereby colloidal NPs are rationally assembled and purified. Two types of functionalized gold NPs (A and B) are bonded to give specific products AB, AB(2), AB(3) and AB(4). The stoichiometry control is realized by fine-tuning the charge repulsion among the B-NPs. The products are protected by a polymer, which allows their isolation in high purity. The integration of hetero-assembly, stoichiometry control, protection scheme and separation method may provide a scalable way to fabricate sophisticated nanostructures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981012"}
{"pmid": "20981013", "title": "Two-dimensional superconductivity at a Mott insulator/band insulator interface LaTiO3/SrTiO3.", "content": "Two-dimensional superconductivity at a Mott insulator/band insulator interface LaTiO3/SrTiO3. Transition metal oxides show a great variety of quantum electronic behaviours where correlations often have an important role. The achievement of high-quality epitaxial interfaces involving such materials gives a unique opportunity to engineer artificial structures where new electronic orders take place. One of the most striking result in this area is the recent observation of a two-dimensional electron gas at the interface between a strongly correlated Mott insulator LaTiO(3) and a band insulator SrTiO(3). The mechanism responsible for such a behaviour is still under debate. In particular, the influence of the nature of the insulator has to be clarified. In this article, we show that despite the expected electronic correlations, LaTiO(3)/SrTiO(3) heterostructures undergo a superconducting transition at a critical temperature T(c)(onset)~300 mK. We have found that the superconducting electron gas is confined over a typical thickness of 12 nm and is located mostly on the SrTiO(3) substrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981013"}
{"pmid": "20981010", "title": "Bottom-up effects of plant diversity on multitrophic interactions in a biodiversity experiment.", "content": "Bottom-up effects of plant diversity on multitrophic interactions in a biodiversity experiment. Biodiversity is rapidly declining, and this may negatively affect ecosystem processes, including economically important ecosystem services. Previous studies have shown that biodiversity has positive effects on organisms and processes across trophic levels. However, only a few studies have so far incorporated an explicit food-web perspective. In an eight-year biodiversity experiment, we studied an unprecedented range of above- and below-ground organisms and multitrophic interactions. A multitrophic data set originating from a single long-term experiment allows mechanistic insights that would not be gained from meta-analysis of different experiments. Here we show that plant diversity effects dampen with increasing trophic level and degree of omnivory. This was true both for abundance and species richness of organisms. Furthermore, we present comprehensive above-ground/below-ground biodiversity food webs. Both above ground and below ground, herbivores responded more strongly to changes in plant diversity than did carnivores or omnivores. Density and richness of carnivorous taxa was independent of vegetation structure. Below-ground responses to plant diversity were consistently weaker than above-ground responses. Responses to increasing plant diversity were generally positive, but were negative for biological invasion, pathogen infestation and hyperparasitism. Our results suggest that plant diversity has strong bottom-up effects on multitrophic interaction networks, with particularly strong effects on lower trophic levels. Effects on higher trophic levels are indirectly mediated through bottom-up trophic cascades.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981010"}
{"pmid": "20981016", "title": "Evidence for infragravity wave-tide resonance in deep oceans.", "content": "Evidence for infragravity wave-tide resonance in deep oceans. Ocean tides are the oscillatory motions of seawater forced by the gravitational attraction of the Moon and Sun with periods of a half to a day and wavelengths of the semi-Pacific to Pacific scale. Ocean infragravity (IG) waves are sea-surface gravity waves with periods of several minutes and wavelengths of several dozen kilometres. Here we report the first evidence of the resonance between these two ubiquitous phenomena, mutually very different in period and wavelength, in deep oceans. The evidence comes from long-term, large-scale observations with arrays of broadband ocean-bottom seismometers located at depths of more than 4,000 m in the Pacific Ocean. This observational evidence is substantiated by a theoretical argument that IG waves and the tide can resonantly couple and that such coupling occurs over unexpectedly wide areas of the Pacific Ocean. Through this resonant coupling, some of ocean tidal energy is transferred in deep oceans to IG wave energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981016"}
{"pmid": "20981015", "title": "A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.", "content": "A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. NMDA receptors are tetrameric complexes of NR1 and NR2A-D subunits that mediate excitatory synaptic transmission and have a role in neurological disorders. In this article, we identify a novel subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit, which could allow selective modification of circuit function in regions expressing NR2C/D subunits. The substituted tetrahydroisoquinoline CIQ (3-chlorophenyl)(6,7-dimethoxy-1-((4-methoxyphenoxy)methyl)-3,4-dihydroisoquinolin-2(1H)-yl)methanone) enhances receptor responses two-fold with an EC(50) of 3 μM by increasing channel opening frequency without altering mean open time or EC(50) values for glutamate or glycine. The actions of CIQ depend on a single residue in the M1 region (NR2D Thr592) and on the linker between the N-terminal domain and agonist binding domain. CIQ potentiates native NR2D-containing NMDA receptor currents from subthalamic neurons. Our identification of a subunit-selective NMDA receptor modulator reveals a new class of pharmacological tools with which to probe the role of NR2C- and NR2D-containing NMDA receptors in brain function and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981015"}
{"pmid": "20981014", "title": "Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A.", "content": "Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A. Dyrk1A (dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A) is a serine/threonine kinase essential for brain development and function, and its excessive activity is considered a pathogenic factor in Down syndrome. The development of potent, selective inhibitors of Dyrk1A would help to elucidate the molecular mechanisms of normal and diseased brains, and may provide a new lead compound for molecular-targeted drug discovery. Here, we report a novel Dyrk1A inhibitor, INDY, a benzothiazole derivative showing a potent ATP-competitive inhibitory effect with IC(50) and K(i) values of 0.24 and 0.18 μM, respectively. X-ray crystallography of the Dyrk1A/INDY complex revealed the binding of INDY in the ATP pocket of the enzyme. INDY effectively reversed the aberrant tau-phosphorylation and rescued the repressed NFAT (nuclear factor of activated T cell) signalling induced by Dyrk1A overexpression. Importantly, proINDY, a prodrug of INDY, effectively recovered Xenopus embryos from head malformation induced by Dyrk1A overexpression, resulting in normally developed embryos and demonstrating the utility of proINDY in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981014"}
{"pmid": "20981018", "title": "'Quantized' states of the charge-density wave in microcrystals of K(0.3)MoO3.", "content": "'Quantized' states of the charge-density wave in microcrystals of K(0.3)MoO3. Quantization of electrons in solids can typically be observed in microscopic samples if the mean free path of the electrons exceeds the dimensions of the sample. A special case is a quasi one-dimensional metal, in which electrons condense into a collective state. This state, a charge-density wave (CDW), is a periodic modulation of both the lattice and electron density. Here, we demonstrate that samples of K(0.3)MoO(3), a typical CDW conductor, show jumps in conduction, regular in temperature. The jumps correspond to transitions between discrete states of the CDW and reveal the quantization of the wave vector of electrons near the Fermi vector. The effect involves both quantum and classical features of the CDW: the quantum condensate demonstrates modes, resembling those of a classical wave in a resonator. The analysis of the steps allows extremely precise studies of the CDW wave-vector variations and reveals new prospects for structural studies of electronic crystals and fine effects in their electronic states and lattice motions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981018"}
{"pmid": "20981017", "title": "Enhanced proton transport in nanostructured polymer electrolyte/ionic liquid membranes under water-free conditions.", "content": "Enhanced proton transport in nanostructured polymer electrolyte/ionic liquid membranes under water-free conditions. Proton exchange fuel cells (PEFCs) have the potential to provide power for a variety of applications ranging from electronic devices to transportation vehicles. A major challenge towards economically viable PEFCs is finding an electrolyte that is both durable and easily passes protons. In this article, we study novel anhydrous proton-conducting membranes, formed by incorporating ionic liquids into synthetic block co-polymer electrolytes, poly(styrenesulphonate-b-methylbutylene) (S(n)MB(m)), as high-temperature PEFCs. The resulting membranes are transparent, flexible and thermally stable up to 180 °C. The increases in the sulphonation level of S(n)MB(m) co-polymers (proton supplier) and the concentration of the ionic liquid (proton mediator) produce an overall increase in conductivity. Morphology effects were studied by X-ray scattering and electron microscopy. Compared with membranes having discrete ionic domains (including Nafion 117), the nanostructured membranes revealed over an order of magnitude increase in conductivity with the highest conductivity of 0.045 S cm(-1) obtained at 165 °C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981017"}
{"pmid": "20981020", "title": "One-by-one trap activation in silicon nanowire transistors.", "content": "One-by-one trap activation in silicon nanowire transistors. Flicker or 1/f noise in metal-oxide-semiconductor field-effect transistors (MOSFETs) has been identified as the main source of noise at low frequency. It often originates from an ensemble of a huge number of charges becoming trapped and de-trapped. However, as a deviation from the well-known model of 1/f noise is observed for nanoscale MOSFETs, a new model is required. Here, we report the observation of one-by-one trap activation controlled by the gate voltage in a nanowire MOSFET and propose a new low-frequency-noise theory for nanoscale FETs. We show that the Coulomb repulsion between electronically charged trap sites prevents the activation of several traps simultaneously. This effect induces a noise reduction of more than one order of magnitude. It decreases when the electron density in the channel is increased due to the electrical screening of traps. These findings are technologically useful for any FET with a short and narrow channel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981020"}
{"pmid": "20981019", "title": "Effects of electronegative substitution on the optical and electronic properties of acenes and diazaacenes.", "content": "Effects of electronegative substitution on the optical and electronic properties of acenes and diazaacenes. Large acenes, particularly pentacenes, are important in organic electronics applications such as thin-film transistors. Derivatives where CH units are substituted by sp(2) nitrogen atoms are rare but of potential interest as charge-transport materials. In this article, we show that pyrazine units embedded in tetracenes and pentacenes allow for additional electronegative substituents to induce unexpected redshifts in the optical transitions of diazaacenes. The presence of the pyrazine group is critical for this effect. The decrease in transition energy in the halogenated diazaacenes is due to a disproportionate lack of stabilization of the HOMO on halogen substitution. The effect results from the unsymmetrical distribution of the HOMO, which shows decreased orbital coefficients on the ring bearing chlorine substituents. The more strongly electron-accepting cyano group is predicted to shift the transitions of diazaacenes even further to the red. Electronegative substitution impacts the electronic properties of diazaacenes to a much greater degree than expected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981019"}
{"pmid": "20981021", "title": "Piezoelectric-nanowire-enabled power source for driving wireless microelectronics.", "content": "Piezoelectric-nanowire-enabled power source for driving wireless microelectronics. Harvesting energy from irregular/random mechanical actions in variable and uncontrollable environments is an effective approach for powering wireless mobile electronics to meet a wide range of applications in our daily life. Piezoelectric nanowires are robust and can be stimulated by tiny physical motions/disturbances over a range of frequencies. Here, we demonstrate the first chemical epitaxial growth of PbZr(x)Ti(1-x)O(3) (PZT) nanowire arrays at 230 °C and their application as high-output energy converters. The nanogenerators fabricated using a single array of PZT nanowires produce a peak output voltage of ~0.7 V, current density of 4 μA cm(-2) and an average power density of 2.8 mW cm(-3). The alternating current output of the nanogenerator is rectified, and the harvested energy is stored and later used to light up a commercial laser diode. This work demonstrates the feasibility of using nanogenerators for powering mobile and even personal microelectronics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981021"}
{"pmid": "20981022", "title": "Creation of a two-dimensional electron gas at an oxide interface on silicon.", "content": "Creation of a two-dimensional electron gas at an oxide interface on silicon. In recent years, reversible control over metal-insulator transition has been shown, at the nanoscale, in a two-dimensional electron gas (2DEG) formed at the interface between two complex oxides. These materials have thus been suggested as possible platforms for developing ultrahigh-density oxide nanoelectronics. A prerequisite for the development of these new technologies is the integration with existing semiconductor electronics platforms. Here, we demonstrate room-temperature conductivity switching of 2DEG nanowires formed at atomically sharp LaAlO(3)/SrTiO(3) (LAO/STO) heterointerfaces grown directly on (001) Silicon (Si) substrates. The room-temperature electrical transport properties of LAO/STO heterointerfaces on Si are comparable with those formed from a SrTiO(3) bulk single crystal. The ability to form reversible conducting nanostructures directly on Si wafers opens new opportunities to incorporate ultrahigh-density oxide nanoelectronic memory and logic elements into well-established Si-based platforms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981022"}
{"pmid": "20981023", "title": "Structural bases for the interaction of frataxin with the central components of iron-sulphur cluster assembly.", "content": "Structural bases for the interaction of frataxin with the central components of iron-sulphur cluster assembly. Reduced levels of frataxin, an essential protein of as yet unknown function, are responsible for causing the neurodegenerative pathology Friedreich's ataxia. Independent reports have linked frataxin to iron-sulphur cluster assembly through interactions with the two central components of this machinery: desulphurase Nfs1/IscS and the scaffold protein Isu/IscU. In this study, we use a combination of biophysical methods to define the structural bases of the interaction of CyaY (the bacterial orthologue of frataxin) with the IscS/IscU complex. We show that CyaY binds IscS as a monomer in a pocket between the active site and the IscS dimer interface. Recognition does not require iron and occurs through electrostatic interactions of complementary charged residues. Mutations at the complex interface affect the rates of enzymatic cluster formation. CyaY binding strengthens the affinity of the IscS/IscU complex. Our data suggest a new paradigm for understanding the role of frataxin as a regulator of IscS functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981023"}
{"pmid": "20981024", "title": "Tectorial membrane travelling waves underlie abnormal hearing in Tectb mutant mice.", "content": "Tectorial membrane travelling waves underlie abnormal hearing in Tectb mutant mice. Remarkable sensitivity and exquisite frequency selectivity are hallmarks of mammalian hearing, but their underlying mechanisms remain unclear. Cochlear insults and hearing disorders that decrease sensitivity also tend to broaden tuning, suggesting that these properties are linked. However, a recently developed mouse model of genetically altered hearing (Tectb(-/-)) shows decreased sensitivity and sharper frequency selectivity. In this paper, we show that the Tectb mutation reduces the spatial extent and propagation velocity of tectorial membrane (TM) travelling waves and that these changes in wave propagation are likely to account for all of the hearing abnormalities associated with the mutation. By reducing the spatial extent of TM waves, the Tectb mutation decreases the spread of excitation and thereby increases frequency selectivity. Furthermore, the change in TM wave velocity reduces the number of hair cells that effectively couple energy to the basilar membrane, which reduces sensitivity. These results highlight the importance of TM waves in hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981024"}
{"pmid": "20981025", "title": "A role for TREX components in the release of spliced mRNA from nuclear speckle domains.", "content": "A role for TREX components in the release of spliced mRNA from nuclear speckle domains. The TREX complex, which functions in mRNA export, is recruited to mRNA during splicing. Both the splicing machinery and the TREX complex are concentrated in 20-50 discrete foci known as nuclear speckle domains. In this study, we use a model system where DNA constructs are microinjected into HeLa cell nuclei, to follow the fates of the transcripts. We show that transcripts lacking functional splice sites, which are inefficiently exported, do not associate with nuclear speckle domains but are instead distributed throughout the nucleoplasm. In contrast, pre-mRNAs containing functional splice sites accumulate in nuclear speckles, and our data suggest that splicing occurs in these domains. When the TREX components UAP56 or Aly are knocked down, spliced mRNA, as well as total polyA+ RNA, accumulates in nuclear speckle domains. Together, our data raise the possibility that pre-mRNA undergoes splicing in nuclear speckle domains, before their release by TREX components for efficient export to the cytoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981025"}
{"pmid": "20981026", "title": "Second-generation environmental sequencing unmasks marine metazoan biodiversity.", "content": "Second-generation environmental sequencing unmasks marine metazoan biodiversity. Biodiversity is of crucial importance for ecosystem functioning, sustainability and resilience, but the magnitude and organization of marine diversity at a range of spatial and taxonomic scales are undefined. In this paper, we use second-generation sequencing to unmask putatively diverse marine metazoan biodiversity in a Scottish temperate benthic ecosystem. We show that remarkable differences in diversity occurred at microgeographical scales and refute currently accepted ecological and taxonomic paradigms of meiofaunal identity, rank abundance and concomitant understanding of trophic dynamics. Richness estimates from the current benchmarked Operational Clustering of Taxonomic Units from Parallel UltraSequencing analyses are broadly aligned with those derived from morphological assessments. However, the slope of taxon rarefaction curves for many phyla remains incomplete, suggesting that the true alpha diversity is likely to exceed current perceptions. The approaches provide a rapid, objective and cost-effective taxonomic framework for exploring links between ecosystem structure and function of all hitherto intractable, but ecologically important, communities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981026"}
{"pmid": "20981028", "title": "Protein-binding assays in biological liquids using microscale thermophoresis.", "content": "Protein-binding assays in biological liquids using microscale thermophoresis. Protein interactions inside the human body are expected to differ from the situation in vitro. This is crucial when investigating protein functions or developing new drugs. In this study, we present a sample-efficient, free-solution method, termed microscale thermophoresis, that is capable of analysing interactions of proteins or small molecules in biological liquids such as blood serum or cell lysate. The technique is based on the thermophoresis of molecules, which provides information about molecule size, charge and hydration shell. We validated the method using immunologically relevant systems including human interferon gamma and the interaction of calmodulin with calcium. The affinity of the small-molecule inhibitor quercetin to its kinase PKA was determined in buffer and human serum, revealing a 400-fold reduced affinity in serum. This information about the influence of the biological matrix may allow to make more reliable conclusions on protein functionality, and may facilitate more efficient drug development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981028"}
{"pmid": "20981027", "title": "Dynamic evolution of precise regulatory encodings creates the clustered site signature of enhancers.", "content": "Dynamic evolution of precise regulatory encodings creates the clustered site signature of enhancers. Concentration gradients of morphogenic proteins pattern the embryonic axes of Drosophila by activating different genes at different concentrations. The neurogenic ectoderm enhancers (NEEs) activate different genes at different threshold levels of the Dorsal (Dl) morphogen, which patterns the dorsal/ventral axis. NEEs share a unique arrangement of highly constrained DNA-binding sites for Dl, Twist (Twi), Snail (Sna) and Suppressor of Hairless (Su(H)), and encode the threshold variable in the precise length of DNA that separates one well-defined Dl element from a Twi element. However, NEEs also possess dense clusters of variant Dl sites. Here, we show that these increasingly variant sites are eclipsed relic elements, which were superseded by more recently evolved threshold encodings. Given the divergence in egg size during Drosophila lineage evolution, the observed characteristic clusters of divergent sites indicate a history of frequent selection for changes in threshold responses to the Dl morphogen gradient and confirm the NEE structure/function model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981027"}
{"pmid": "20981029", "title": "G-protein β2 subunit interacts with mitofusin 1 to regulate mitochondrial fusion.", "content": "G-protein β2 subunit interacts with mitofusin 1 to regulate mitochondrial fusion. Mitofusins (Mfns) mediate the fusion of mitochondrial membranes. However, little is known about how Mfns are regulated to control mitochondrial fusion, which is a multistep process requiring tethering and docking of the outer membranes of two mitochondria. In this study, we report that guanine nucleotide binding protein-β subunit 2 (Gβ2), a WD40 repeats protein and a member of the β-subunits of the heterotrimeric G proteins, has a crucial function in mitochondrial fusion. Gβ2 was found to be enriched on the surface of mitochondria and interacted with mitofusin 1 (Mfn1) specifically. Gβ2 also regulated the mobility of Mfn1 on the surface of the mitochondrial membrane and affected the mitochondrial fusion. Depletion of endogenous Gβ2 resulted in mitochondrial fragmentation, which could be rescued by exogenous Gβ2. These findings have thus uncovered a novel role of Gβ2 in regulating mitochondrial fusion through its interaction with Mfn1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981029"}
{"pmid": "20981031", "title": "From casual blood pressure measurement to long-term blood pressure burden: better elucidation of the association between versatile blood pressures and cardiovascular events.", "content": "From casual blood pressure measurement to long-term blood pressure burden: better elucidation of the association between versatile blood pressures and cardiovascular events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981031"}
{"pmid": "20981032", "title": "Expression of N-type calcium channels in human adrenocortical cells and their contribution to corticosteroid synthesis.", "content": "Expression of N-type calcium channels in human adrenocortical cells and their contribution to corticosteroid synthesis. The inhibition of aldosterone activity is a useful approach for preventing the progression of cardiovascular and renal diseases in hypertensive patients. Although the results of our previous in vivo study suggested that N-type calcium channels may have a role in regulating plasma aldosterone levels, the direct relationship between N-type calcium channels and aldosterone production in adrenocortical cells has not been examined. In this study, the analysis of quantitative reverse transcription-PCR, western blotting, and immunocytological staining indicated the possible presence of N-type calcium channels in human adrenocortical cells (H295R cell line). Patch clamp analysis indicated that omega-conotoxin GVIA (CnTX), an N-type calcium channel inhibitor, suppressed voltage-dependent barium currents. During steroidogenesis, CnTX significantly reduced the transient calcium signaling induced by angiotensin II (Ang II) and partially prevented Ang II-induced aldosterone and cortisol formation with no significant influence on CYP11B2 and CYP11B1 mRNA expression. In addition, in α1B calcium channel subunits, knockdown significantly decreased Ang II-induced aldosterone formation with increments in CYP11B2 mRNA expression. We also investigated the inhibitory activities of some types of dihydropyridine calcium channel blockers (CCBs; cilnidipine: L-/N-type CCB, efonidipine: L-/T-type CCB, and nifedipine: L-type CCB), and these agents showed a dose-dependent inhibition effect on Ang II-induced aldosterone and cortisol production. Furthermore, only cilnidipine failed to suppress CYP11B1 expression in H295R cells. These results suggest that N-type calcium channels have a significant role in transducing the Ang II signal for aldosterone (and cortisol) biosynthesis, which may explain the mechanism by which N-type calcium channels regulate plasma aldosterone levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981032"}
{"pmid": "20981033", "title": "The risk of cold temperature: an important aspect of the determination of morning blood pressure surge.", "content": "The risk of cold temperature: an important aspect of the determination of morning blood pressure surge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981033"}
{"pmid": "20981034", "title": "Reactive oxygen species and vascular biology: implications in human hypertension.", "content": "Reactive oxygen species and vascular biology: implications in human hypertension. Increased vascular production of reactive oxygen species (ROS; termed oxidative stress) has been implicated in various chronic diseases, including hypertension. Oxidative stress is both a cause and a consequence of hypertension. Although oxidative injury may not be the sole etiology, it amplifies blood pressure elevation in the presence of other pro-hypertensive factors. Oxidative stress is a multisystem phenomenon in hypertension and involves the heart, kidneys, nervous system, vessels and possibly the immune system. Compelling experimental and clinical evidence indicates the importance of the vasculature in the pathophysiology of hypertension and as such much emphasis has been placed on the (patho)biology of ROS in the vascular system. A major source for cardiovascular, renal and neural ROS is a family of non-phagocytic nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (Nox), including the prototypic Nox2 homolog-based NADPH oxidase, as well as other Noxes, such as Nox1 and Nox4. Nox-derived ROS is important in regulating endothelial function and vascular tone. Oxidative stress is implicated in endothelial dysfunction, inflammation, hypertrophy, apoptosis, migration, fibrosis, angiogenesis and rarefaction, important processes involved in vascular remodeling in hypertension. Despite a plethora of data implicating oxidative stress as a causative factor in experimental hypertension, findings in human hypertension are less conclusive. This review highlights the importance of ROS in vascular biology and focuses on the potential role of oxidative stress in human hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981034"}
{"pmid": "20981030", "title": "B-cell depletion reveals a role for antibodies in the control of chronic HIV-1 infection.", "content": "B-cell depletion reveals a role for antibodies in the control of chronic HIV-1 infection. HIV can be partially contained by host immunity and understanding the basis of this may inform vaccine design. The importance of B-cell function in long-term control is poorly understood. One method of investigating this is in vivo cellular depletion. In this study, we take advantage of a unique opportunity to investigate the role of B cells in an HIV-infected patient. The HIV-1(+) patient studied here was not taking antiretroviral drugs and was treated for pre-existing low-grade lymphoplasmacytoid lymphoma by depletion of CD20+ B cells using rituximab. We demonstrate that B-cell depletion results in a decline in autologous neutralizing antibody (NAb) responses and a 1.7 log(10) rise in HIV-1 plasma viral load (pVL). The recovery of NAbs results in a decline in pVL. The HIV-1 sequences diversify and NAb-resistant mutants are subsequently selected. These data suggest that B-cell function can contribute to the long-term control of pVL, and that NAbs may be more important in controlling chronic HIV-1 infection than previously suspected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981030"}
{"pmid": "20981035", "title": "The ENPP1 K121Q polymorphism is not associated with type 2 diabetes or obesity in the Chinese Han population.", "content": "The ENPP1 K121Q polymorphism is not associated with type 2 diabetes or obesity in the Chinese Han population. Type 2 diabetes (T2D) mellitus is a metabolic disorder characterized by chronic hyperglycemia and insulin resistance. It has been a worldwide public health problem, which is increasing rapidly, especially in developing countries such as China. The ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) gene, also known as plasma cell membrane glycoprotein 1, has been reported by genetic association studies as being associated with T2D and obesity in various populations, such as Caucasian and African American. However, there are also some controversial results in Asian populations. Our study tried to examine the associations between ENPP1 and T2D and obesity. Rs1044498 (K121Q) and rs7754561 were genotyped in 1912 patients and 2041 control subjects through TaqMan technology on the ABI7900 system. They showed no statistical association with T2D, obesity or any metabolic quantitative traits. Our meta-analysis result was consistent with it. Our study did not replicate the positive association found previously and suggested that K121Q of ENPP1 might not have a major role in the susceptibility to T2D or obesity in the Chinese Han population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981035"}
{"pmid": "20981036", "title": "Clinical application of array-based comparative genomic hybridization by two-stage screening for 536 patients with mental retardation and multiple congenital anomalies.", "content": "Clinical application of array-based comparative genomic hybridization by two-stage screening for 536 patients with mental retardation and multiple congenital anomalies. Recent advances in the analysis of patients with congenital abnormalities using array-based comparative genome hybridization (aCGH) have uncovered two types of genomic copy-number variants (CNVs); pathogenic CNVs (pCNVs) relevant to congenital disorders and benign CNVs observed also in healthy populations, complicating the screening of disease-associated alterations by aCGH. To apply the aCGH technique to the diagnosis as well as investigation of multiple congenital anomalies and mental retardation (MCA/MR), we constructed a consortium with 23 medical institutes and hospitals in Japan, and recruited 536 patients with clinically uncharacterized MCA/MR, whose karyotypes were normal according to conventional cytogenetics, for two-stage screening using two types of bacterial artificial chromosome-based microarray. The first screening using a targeted array detected pCNV in 54 of 536 cases (10.1%), whereas the second screening of the 349 cases negative in the first screening using a genome-wide high-density array at intervals of approximately 0.7 Mb detected pCNVs in 48 cases (13.8%), including pCNVs relevant to recently established microdeletion or microduplication syndromes, CNVs containing pathogenic genes and recurrent CNVs containing the same region among different patients. The results show the efficient application of aCGH in the clinical setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981036"}
{"pmid": "20981037", "title": "Y-chromosome R-M343 African lineages and sickle cell disease reveal structured assimilation in Lebanon.", "content": "Y-chromosome R-M343 African lineages and sickle cell disease reveal structured assimilation in Lebanon. We have sought to identify signals of assimilation of African male lines in Lebanon by exploring the association of sickle cell disease (SCD) in Lebanon with Y-chromosome haplogroups that are informative of the disease origin and its exclusivity to the Muslim community. A total of 732 samples were analyzed, including 33 SCD patients from Lebanon genotyped for 28 binary markers and 19 short tandem repeats on the non-recombinant segment of the Y chromosome. Genetic organization was identified using populations known to have influenced the genetic structure of the Lebanese population, in addition to African populations with high incidence of SCD. Y-chromosome haplogroup R-M343 sub-lineages distinguish between sub-Saharan African and Lebanese Y chromosomes. We detected a limited penetration of SCD into Lebanese R-M343 carriers, restricted to Lebanese Muslims. We suggest that this penetration brought the sickle cell gene along with the African R-M343, probably with the Saharan caravan slave trade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981037"}
{"pmid": "20981038", "title": "Association of serotonin transporter gene variation with smoking, chronic obstructive pulmonary disease, and its depressive symptoms.", "content": "Association of serotonin transporter gene variation with smoking, chronic obstructive pulmonary disease, and its depressive symptoms. A serotonin transporter gene, SLC6A4, is thought to be related to nicotine dependence and depression, one of the comorbidities of chronic obstructive pulmonary disease (COPD). To investigate the association between SLC6A4 variation and tobacco consumption, susceptibility to COPD, and depression status. In all, 247 patients with COPD and 119 control subjects were genotyped for 5 tag single-nucleotide polymorphisms (SNPs) of SLC6A4. We analyzed the correlation between these genotypes and COPD, using the results of a pulmonary function test or chest computed tomography; data on tobacco consumption (pack-years); and the depression score based on the hospital anxiety and depression scale (HADS) after adjusting for age, gender, and smoking status (and pack-years, when appropriate). The rare allele rs2020936 was significantly associated with COPD incidence in the trend model (P = 0.003; odds ratio, 2.20; 95% confidence interval, 1.31-3.74). This allele was also associated with the number of pack-years (P = 0.026). The major allele of another SNP of SLC6A4, namely rs3794808, correlated with the HADS depression score (P = 0.016). We conclude that SLC6A4 variation affects COPD pathogenesis, and this effect depends partly on tobacco consumption. SLC6A4 variation also affects depressive symptoms. SLC6A4 could be modified to prevent COPD and treat the depressive symptoms of COPD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981038"}
{"pmid": "20981040", "title": "Regional disaster planning for neonatology.", "content": "Regional disaster planning for neonatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981040"}
{"pmid": "20981039", "title": "Chromosome 17q21 SNP and severe asthma.", "content": "Chromosome 17q21 SNP and severe asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981039"}
{"pmid": "20981041", "title": "Lacrimal gland choristoma in a preterm infant, presenting with spontaneous hyphema and increased intraocular pressure.", "content": "Lacrimal gland choristoma in a preterm infant, presenting with spontaneous hyphema and increased intraocular pressure. We report a case of intraocular lacrimal gland choristoma presenting very early in a preterm infant with hyphema, a mass lesion and raised intraocular pressure. Enucleation of the involved eye, which is the treatment in most cases, was performed and prosthesis was fitted successfully. An interesting additional finding in our patient was a choroidal defect, not reported to date with other cases in the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981041"}
{"pmid": "20981042", "title": "Prenatally diagnosed left ventricular diverticulum with thoracoabdominal wall defect: a case and review of the literature.", "content": "Prenatally diagnosed left ventricular diverticulum with thoracoabdominal wall defect: a case and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981042"}
{"pmid": "20981045", "title": "Volatile accretion history of the Earth.", "content": "Volatile accretion history of the Earth. It has long been thought that the Earth had a protracted and complex history of volatile accretion and loss. Albarède paints a different picture, proposing that the Earth first formed as a dry planet which, like the Moon, was devoid of volatile constituents. He suggests that the Earth's complement of volatile elements was only established later, by the addition of a small veneer of volatile-rich material at ∼100 Myr (here and elsewhere, ages are relative to the origin of the Solar System). Here we argue that the Earth's mass balance of moderately volatile elements is inconsistent with Albarède's hypothesis but is well explained by the standard model of accretion from partially volatile-depleted material, accompanied by core formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981045"}
{"pmid": "20981044", "title": "Preventing mother-to-child transmission of HIV in urban Zimbabwe.", "content": "Preventing mother-to-child transmission of HIV in urban Zimbabwe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981044"}
{"pmid": "20981046", "title": "Not quite assured.", "content": "Not quite assured.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981046"}
{"pmid": "20981047", "title": "The innovation game.", "content": "The innovation game.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981047"}
{"pmid": "20981048", "title": "Space hitch-hiker.", "content": "Space hitch-hiker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981048"}
{"pmid": "20981061", "title": "Glimpsing a comet's heart.", "content": "Glimpsing a comet's heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981061"}
{"pmid": "20981049", "title": "Spending review leaves research in the lurch.", "content": "Spending review leaves research in the lurch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981049"}
{"pmid": "20981062", "title": "Verbal autopsy methods questioned.", "content": "Verbal autopsy methods questioned.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981062"}
{"pmid": "20981063", "title": "UK scientists celebrate budget reprieve.", "content": "UK scientists celebrate budget reprieve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981063"}
{"pmid": "20981064", "title": "Quake threat looms over Haiti.", "content": "Quake threat looms over Haiti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981064"}
{"pmid": "20981065", "title": "Mystery fraud accusations.", "content": "Mystery fraud accusations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981065"}
{"pmid": "20981066", "title": "Mountaintop mining plans close to defeat.", "content": "Mountaintop mining plans close to defeat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981066"}
{"pmid": "20981067", "title": "Human genome: Genomes by the thousand.", "content": "Human genome: Genomes by the thousand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981067"}
{"pmid": "20981068", "title": "Space science: The telescope that ate astronomy.", "content": "Space science: The telescope that ate astronomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981068"}
{"pmid": "20981069", "title": "Long shadow of the stem-cell ruling.", "content": "Long shadow of the stem-cell ruling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981069"}
{"pmid": "20981079", "title": "Fate of 'retired' research chimps.", "content": "Fate of 'retired' research chimps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981079"}
{"pmid": "20981080", "title": "Marine stewardship: catalysing change.", "content": "Marine stewardship: catalysing change.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981080"}
{"pmid": "20981081", "title": "Pakistan: the brain drain dilemma.", "content": "Pakistan: the brain drain dilemma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981081"}
{"pmid": "20981082", "title": "Pakistan: why the reforms need work.", "content": "Pakistan: why the reforms need work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981082"}
{"pmid": "20981083", "title": "Safaris can help conservation.", "content": "Safaris can help conservation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981083"}
{"pmid": "20981084", "title": "Georges Charpak (1924-2010).", "content": "Georges Charpak (1924-2010).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981084"}
{"pmid": "20981085", "title": "Genomics: In search of rare human variants.", "content": "Genomics: In search of rare human variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981085"}
{"pmid": "20981086", "title": "Drug development: Longer-lived proteins.", "content": "Drug development: Longer-lived proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981086"}
{"pmid": "20981087", "title": "Biogeochemistry: Phosphorus and the gust of fresh air.", "content": "Biogeochemistry: Phosphorus and the gust of fresh air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981087"}
{"pmid": "20981088", "title": "Cancer: Genomic evolution of metastasis.", "content": "Cancer: Genomic evolution of metastasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981088"}
{"pmid": "20981089", "title": "Stem cells: The intestinal-crypt casino.", "content": "Stem cells: The intestinal-crypt casino.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981089"}
{"pmid": "20981090", "title": "Astrophysics: Weighing in on neutron stars.", "content": "Astrophysics: Weighing in on neutron stars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981090"}
{"pmid": "20981091", "title": "Structural biology: A peep through anion channels.", "content": "Structural biology: A peep through anion channels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981091"}
{"pmid": "20981094", "title": "A two-solar-mass neutron star measured using Shapiro delay.", "content": "A two-solar-mass neutron star measured using Shapiro delay. Neutron stars are composed of the densest form of matter known to exist in our Universe, the composition and properties of which are still theoretically uncertain. Measurements of the masses or radii of these objects can strongly constrain the neutron star matter equation of state and rule out theoretical models of their composition. The observed range of neutron star masses, however, has hitherto been too narrow to rule out many predictions of 'exotic' non-nucleonic components. The Shapiro delay is a general-relativistic increase in light travel time through the curved space-time near a massive body. For highly inclined (nearly edge-on) binary millisecond radio pulsar systems, this effect allows us to infer the masses of both the neutron star and its binary companion to high precision. Here we present radio timing observations of the binary millisecond pulsar J1614-2230 that show a strong Shapiro delay signature. We calculate the pulsar mass to be (1.97 ± 0.04)M(⊙), which rules out almost all currently proposed hyperon or boson condensate equations of state (M(⊙), solar mass). Quark matter can support a star this massive only if the quarks are strongly interacting and are therefore not 'free' quarks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981094"}
{"pmid": "20981093", "title": "Homologue structure of the SLAC1 anion channel for closing stomata in leaves.", "content": "Homologue structure of the SLAC1 anion channel for closing stomata in leaves. The plant SLAC1 anion channel controls turgor pressure in the aperture-defining guard cells of plant stomata, thereby regulating the exchange of water vapour and photosynthetic gases in response to environmental signals such as drought or high levels of carbon dioxide. Here we determine the crystal structure of a bacterial homologue (Haemophilus influenzae) of SLAC1 at 1.20 Å resolution, and use structure-inspired mutagenesis to analyse the conductance properties of SLAC1 channels. SLAC1 is a symmetrical trimer composed from quasi-symmetrical subunits, each having ten transmembrane helices arranged from helical hairpin pairs to form a central five-helix transmembrane pore that is gated by an extremely conserved phenylalanine residue. Conformational features indicate a mechanism for control of gating by kinase activation, and electrostatic features of the pore coupled with electrophysiological characteristics indicate that selectivity among different anions is largely a function of the energetic cost of ion dehydration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981093"}
{"pmid": "20981095", "title": "Detecting excitation and magnetization of individual dopants in a semiconductor.", "content": "Detecting excitation and magnetization of individual dopants in a semiconductor. An individual magnetic atom doped into a semiconductor is a promising building block for bottom-up spintronic devices and quantum logic gates. Moreover, it provides a perfect model system for the atomic-scale investigation of fundamental effects such as magnetism in dilute magnetic semiconductors. However, dopants in semiconductors so far have not been studied by magnetically sensitive techniques with atomic resolution that correlate the atomic structure with the dopant's magnetism. Here we show electrical excitation and read-out of a spin associated with a single magnetic dopant in a semiconductor host. We use spin-resolved scanning tunnelling spectroscopy to measure the spin excitations and the magnetization curve of individual iron surface-dopants embedded within a two-dimensional electron gas confined to an indium antimonide (110) surface. The dopants act like isolated quantum spins the states of which are governed by a substantial magnetic anisotropy that forces the spin to lie in the surface plane. This result is corroborated by our first principles calculations. The demonstrated methodology opens new routes for the investigation of sample systems that are more widely studied in the field of spintronics-that is, Mn in GaAs (ref. 5), magnetic ions in semiconductor quantum dots, nitrogen-vacancy centres in diamond and phosphorus spins in silicon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981095"}
{"pmid": "20981097", "title": "Deformation of the lowermost mantle from seismic anisotropy.", "content": "Deformation of the lowermost mantle from seismic anisotropy. The lowermost part of the Earth's mantle-known as D″-shows significant seismic anisotropy, the variation of seismic wave speed with direction. This is probably due to deformation-induced alignment of MgSiO(3)-post-perovskite (ppv), which is believed to be the main mineral phase present in the region. If this is the case, then previous measurements of D″ anisotropy, which are generally made in one direction only, are insufficient to distinguish candidate mechanisms of slip in ppv because the mineral is orthorhombic. Here we measure anisotropy in D″ beneath North and Central America, where material from subducting oceanic slabs impinges on the core-mantle boundary, using shallow as well as deep earthquakes to increase the azimuthal coverage in D″. We make more than 700 individual measurements of shear wave splitting in D″ in three regions from two different azimuths in each case. We show that the previously assumed case of vertical transverse isotropy (where wave speed shows no azimuthal variation) is not possible, and that more complicated mechanisms must be involved. We test the fit of different MgSiO(3)-ppv deformation mechanisms to our results and find that shear on (001) is most consistent with observations and the expected shear above the core-mantle boundary beneath subduction zones. With new models of mantle flow, or improved experimental determination of the dominant ppv slip systems, this method will allow us to map deformation at the core-mantle boundary and link processes in D″, such as plume initiation, to the rest of the mantle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981097"}
{"pmid": "20981096", "title": "The evolution of the marine phosphate reservoir.", "content": "The evolution of the marine phosphate reservoir. Phosphorus is a biolimiting nutrient that has an important role in regulating the burial of organic matter and the redox state of the ocean-atmosphere system. The ratio of phosphorus to iron in iron-oxide-rich sedimentary rocks can be used to track dissolved phosphate concentrations if the dissolved silica concentration of sea water is estimated. Here we present iron and phosphorus concentration ratios from distal hydrothermal sediments and iron formations through time to study the evolution of the marine phosphate reservoir. The data suggest that phosphate concentrations have been relatively constant over the Phanerozoic eon, the past 542 million years (Myr) of Earth's history. In contrast, phosphate concentrations seem to have been elevated in Precambrian oceans. Specifically, there is a peak in phosphorus-to-iron ratios in Neoproterozoic iron formations dating from ∼750 to ∼635 Myr ago, indicating unusually high dissolved phosphate concentrations in the aftermath of widespread, low-latitude 'snowball Earth' glaciations. An enhanced postglacial phosphate flux would have caused high rates of primary productivity and organic carbon burial and a transition to more oxidizing conditions in the ocean and atmosphere. The snowball Earth glaciations and Neoproterozoic oxidation are both suggested as triggers for the evolution and radiation of metazoans. We propose that these two factors are intimately linked; a glacially induced nutrient surplus could have led to an increase in atmospheric oxygen, paving the way for the rise of metazoan life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981096"}
{"pmid": "20981098", "title": "Late middle Eocene epoch of Libya yields earliest known radiation of African anthropoids.", "content": "Late middle Eocene epoch of Libya yields earliest known radiation of African anthropoids. Reconstructing the early evolutionary history of anthropoid primates is hindered by a lack of consensus on both the timing and biogeography of anthropoid origins. Some prefer an ancient (Cretaceous) origin for anthropoids in Africa or some other Gondwanan landmass, whereas others advocate a more recent (early Cenozoic) origin for anthropoids in Asia, with subsequent dispersal of one or more early anthropoid taxa to Africa. The oldest undoubted African anthropoid primates described so far are three species of the parapithecid Biretia from the late middle Eocene Bir El Ater locality of Algeria and the late Eocene BQ-2 site in the Fayum region of northern Egypt. Here we report the discovery of the oldest known diverse assemblage of African anthropoids from the late middle Eocene Dur At-Talah escarpment in central Libya. The primate assemblage from Dur At-Talah includes diminutive species pertaining to three higher-level anthropoid clades (Afrotarsiidae, Parapithecidae and Oligopithecidae) as well as a small species of the early strepsirhine primate Karanisia. The high taxonomic diversity of anthropoids at Dur At-Talah indicates either a much longer interval of anthropoid evolution in Africa than is currently documented in the fossil record or the nearly synchronous colonization of Africa by multiple anthropoid clades at some time during the middle Eocene epoch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981098"}
{"pmid": "20981099", "title": "Fine-scale recombination rate differences between sexes, populations and individuals.", "content": "Fine-scale recombination rate differences between sexes, populations and individuals. Meiotic recombinations contribute to genetic diversity by yielding new combinations of alleles. Recently, high-resolution recombination maps were inferred from high-density single-nucleotide polymorphism (SNP) data using linkage disequilibrium (LD) patterns that capture historical recombination events. The use of these maps has been demonstrated by the identification of recombination hotspots and associated motifs, and the discovery that the PRDM9 gene affects the proportion of recombinations occurring at hotspots. However, these maps provide no information about individual or sex differences. Moreover, locus-specific demographic factors like natural selection can bias LD-based estimates of recombination rate. Existing genetic maps based on family data avoid these shortcomings, but their resolution is limited by relatively few meioses and a low density of markers. Here we used genome-wide SNP data from 15,257 parent-offspring pairs to construct the first recombination maps based on directly observed recombinations with a resolution that is effective down to 10 kilobases (kb). Comparing male and female maps reveals that about 15% of hotspots in one sex are specific to that sex. Although male recombinations result in more shuffling of exons within genes, female recombinations generate more new combinations of nearby genes. We discover novel associations between recombination characteristics of individuals and variants in the PRDM9 gene and we identify new recombination hotspots. Comparisons of our maps with two LD-based maps inferred from data of HapMap populations of Utah residents with ancestry from northern and western Europe (CEU) and Yoruba in Ibadan, Nigeria (YRI) reveal population differences previously masked by noise and map differences at regions previously described as targets of natural selection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981099"}
{"pmid": "20981100", "title": "On-line, voluntary control of human temporal lobe neurons.", "content": "On-line, voluntary control of human temporal lobe neurons. Daily life continually confronts us with an exuberance of external, sensory stimuli competing with a rich stream of internal deliberations, plans and ruminations. The brain must select one or more of these for further processing. How this competition is resolved across multiple sensory and cognitive regions is not known; nor is it clear how internal thoughts and attention regulate this competition. Recording from single neurons in patients implanted with intracranial electrodes for clinical reasons, here we demonstrate that humans can regulate the activity of their neurons in the medial temporal lobe (MTL) to alter the outcome of the contest between external images and their internal representation. Subjects looked at a hybrid superposition of two images representing familiar individuals, landmarks, objects or animals and had to enhance one image at the expense of the other, competing one. Simultaneously, the spiking activity of their MTL neurons in different subregions and hemispheres was decoded in real time to control the content of the hybrid. Subjects reliably regulated, often on the first trial, the firing rate of their neurons, increasing the rate of some while simultaneously decreasing the rate of others. They did so by focusing onto one image, which gradually became clearer on the computer screen in front of their eyes, and thereby overriding sensory input. On the basis of the firing of these MTL neurons, the dynamics of the competition between visual images in the subject's mind was visualized on an external display.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981100"}
{"pmid": "20981101", "title": "The patterns and dynamics of genomic instability in metastatic pancreatic cancer.", "content": "The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Pancreatic cancer is an aggressive malignancy with a five-year mortality of 97-98%, usually due to widespread metastatic disease. Previous studies indicate that this disease has a complex genomic landscape, with frequent copy number changes and point mutations, but genomic rearrangements have not been characterized in detail. Despite the clinical importance of metastasis, there remain fundamental questions about the clonal structures of metastatic tumours, including phylogenetic relationships among metastases, the scale of ongoing parallel evolution in metastatic and primary sites, and how the tumour disseminates. Here we harness advances in DNA sequencing to annotate genomic rearrangements in 13 patients with pancreatic cancer and explore clonal relationships among metastases. We find that pancreatic cancer acquires rearrangements indicative of telomere dysfunction and abnormal cell-cycle control, namely dysregulated G1-to-S-phase transition with intact G2-M checkpoint. These initiate amplification of cancer genes and occur predominantly in early cancer development rather than the later stages of the disease. Genomic instability frequently persists after cancer dissemination, resulting in ongoing, parallel and even convergent evolution among different metastases. We find evidence that there is genetic heterogeneity among metastasis-initiating cells, that seeding metastasis may require driver mutations beyond those required for primary tumours, and that phylogenetic trees across metastases show organ-specific branches. These data attest to the richness of genetic variation in cancer, brought about by the tandem forces of genomic instability and evolutionary selection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981101"}
{"pmid": "20981104", "title": "Genomics: The tough new variants.", "content": "Genomics: The tough new variants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981104"}
{"pmid": "20981103", "title": "Genomics: The search for association.", "content": "Genomics: The search for association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981103"}
{"pmid": "20981105", "title": "Genomics: Seeing more SNPs.", "content": "Genomics: Seeing more SNPs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981105"}
{"pmid": "20981102", "title": "Distant metastasis occurs late during the genetic evolution of pancreatic cancer.", "content": "Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Metastasis, the dissemination and growth of neoplastic cells in an organ distinct from that in which they originated, is the most common cause of death in cancer patients. This is particularly true for pancreatic cancers, where most patients are diagnosed with metastatic disease and few show a sustained response to chemotherapy or radiation therapy. Whether the dismal prognosis of patients with pancreatic cancer compared to patients with other types of cancer is a result of late diagnosis or early dissemination of disease to distant organs is not known. Here we rely on data generated by sequencing the genomes of seven pancreatic cancer metastases to evaluate the clonal relationships among primary and metastatic cancers. We find that clonal populations that give rise to distant metastases are represented within the primary carcinoma, but these clones are genetically evolved from the original parental, non-metastatic clone. Thus, genetic heterogeneity of metastases reflects that within the primary carcinoma. A quantitative analysis of the timing of the genetic evolution of pancreatic cancer was performed, indicating at least a decade between the occurrence of the initiating mutation and the birth of the parental, non-metastatic founder cell. At least five more years are required for the acquisition of metastatic ability and patients die an average of two years thereafter. These data provide novel insights into the genetic features underlying pancreatic cancer progression and define a broad time window of opportunity for early detection to prevent deaths from metastatic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981102"}
{"pmid": "20981092", "title": "A map of human genome variation from population-scale sequencing.", "content": "A map of human genome variation from population-scale sequencing. The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation as a foundation for investigating the relationship between genotype and phenotype. Here we present results of the pilot phase of the project, designed to develop and compare different strategies for genome-wide sequencing with high-throughput platforms. We undertook three projects: low-coverage whole-genome sequencing of 179 individuals from four populations; high-coverage sequencing of two mother-father-child trios; and exon-targeted sequencing of 697 individuals from seven populations. We describe the location, allele frequency and local haplotype structure of approximately 15 million single nucleotide polymorphisms, 1 million short insertions and deletions, and 20,000 structural variants, most of which were previously undescribed. We show that, because we have catalogued the vast majority of common variation, over 95% of the currently accessible variants found in any individual are present in this data set. On average, each person is found to carry approximately 250 to 300 loss-of-function variants in annotated genes and 50 to 100 variants previously implicated in inherited disorders. We demonstrate how these results can be used to inform association and functional studies. From the two trios, we directly estimate the rate of de novo germline base substitution mutations to be approximately 10(-8) per base pair per generation. We explore the data with regard to signatures of natural selection, and identify a marked reduction of genetic variation in the neighbourhood of genes, due to selection at linked sites. These methods and public data will support the next phase of human genetic research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981092"}
{"pmid": "20981111", "title": "Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon.", "content": "Adenovirus-mediated human paraoxonase1 gene transfer to provide protection against the toxicity of the organophosphorus pesticide toxicant diazoxon. Human paraoxonase1 (hPON1) is a potential therapeutic against the toxicity of organophosphorus (OP) pesticides and chemical warfare nerve agents. We tested whether PON1 gene transfer using adenovirus provides protection against the toxicity of the OP diazoxon. Using an adenovirus construct containing hPON1 gene, we showed elevated levels of recombinant hPON1 in vitro in 293A cells and in vivo in mice. The recombinant enzyme was secreted by 293A cells into culture medium and into the systemic circulation of mice. Western blotting revealed that the virally expressed hPON1 had the expected molecular weight of 45 kDa. Recombinant hPON1 in mice was in complex with mouse high-density lipoprotein (HDL) and migrated more slowly than endogenous hPON1 in the human HDL complex. Mice injected with adenovirus expressed PON1 at 600-3480 U ml(-1) on day 5 post-treatment, which is 8-50-fold above endogenous. Six mice expressing hPON1 survived 2LD(50) doses of diazoxon. Four of the six mice survived a second dose of diazoxon (for a total of 4LD(50)) administered 24 h later. In contrast, none of the three mice in the control group survived one 2LD(50) dose. These results show that hPON1 in mice functions as a prophylactic and offers significant protection against lethal doses of diazoxon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981111"}
{"pmid": "20981109", "title": "Irritant activation of epithelial cells is mediated via protease-dependent EGFR activation.", "content": "Irritant activation of epithelial cells is mediated via protease-dependent EGFR activation. Although numerous studies have examined in vivo and in vitro effects of irritants, most focused on events developing hours to days after exposure. Molecular events occurring immediately after skin contact remain incompletely defined. Characterization of early events could lead to the identification of key molecular signals necessary for the production of inflammatory mediators responsible for the signs and symptoms of irritant contact dermatitis (ICD). HaCaT cells treated with sodium lauryl sulfate (SLS), a model irritant, were used to examine early molecular events of ICD. Western analysis showed SLS-mediated induction of early growth response-1 (egr-1), a transcription factor capable of regulating hallmarks of ICD such as angiogenesis, hyperproliferation, and inflammation. Additionally, de novo egr-1 expression was commensurate with transcriptional activation of egr-1 mRNA and heteronuclear RNA. Use of pharmacological inhibitors demonstrated that SLS-induced egr-1 was dependent on MEK1/p44/42 ERK, but not on p38 or JNK signaling. The EGFR inhibitor PD168393 and the metalloprotease inhibitor TAPI-2 both inhibited SLS-induced egr-1. Finally, small interfering RNA silencing of the EGFR diminished SLS-induced egr-1 mRNA. These studies suggest a role of the EGFR in SLS signaling as well as a, to our knowledge, previously unreported association between ICD and EGFR induction of egr-1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981109"}
{"pmid": "20981110", "title": "Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway.", "content": "Transient expression of OCT4 is sufficient to allow human keratinocytes to change their differentiation pathway. In this study, we describe a simple system in which human keratinocytes can be redirected to an alternative differentiation pathway. We transiently transfected freshly isolated human skin keratinocytes with the single transcription factor OCT4. Within 2 days these cells displayed expression of endogenous embryonic genes and showed reduced genomic methylation. More importantly, these cells could be specifically converted into neuronal and contractile mesenchymal cell types. Redirected differentiation was confirmed by expression of neuronal and mesenchymal cell mRNA and protein, and through a functional assay in which the newly differentiated mesenchymal cells contracted collagen gels as efficiently as authentic myofibroblasts. Thus, to generate patient-specific cells for therapeutic purposes, it may not be necessary to completely reprogram somatic cells into induced pluripotent stem cells before altering their differentiation and grafting them into new tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981110"}
{"pmid": "20981112", "title": "Innovative DNA vaccine for human papillomavirus (HPV)-associated head and neck cancer.", "content": "Innovative DNA vaccine for human papillomavirus (HPV)-associated head and neck cancer. Human papillomavirus (HPV), particularly type 16, has been associated with a subset of head and neck cancers. The viral-encoded oncogenic proteins E6 and E7 represent ideal targets for immunotherapy against HPV-associated head and neck cancers. DNA vaccines have emerged as attractive approaches for immunotherapy due to its simplicity, safety and ease of preparation. Intradermal administration of DNA vaccine by means of gene gun represents an efficient method to deliver DNA directly into dendritic cells for priming antigen-specific T cells. We have previously shown that a DNA vaccine encoding an invariant chain (Ii), in which the class II-associated Ii peptide (CLIP) region has been replaced by a Pan-DR-epitope (PADRE) sequence to form Ii-PADRE, is capable of generating PADRE-specific CD4+ T cells in vaccinated mice. In the current study, we hypothesize that a DNA vaccine encoding Ii-PADRE linked to E6 (Ii-PADRE-E6) will further enhance E6-specific CD8+ T cell immune responses through PADRE-specific CD4+ T-helper cells. We found that mice vaccinated with Ii-PADRE-E6 DNA generated comparable levels of PADRE-specific CD4+ T-cell immune responses, as well as significantly stronger E6-specific CD8+ T-cell immune responses and antitumor effects against the lethal challenge of E6-expressing tumor compared with mice vaccinated with Ii-E6 DNA. Taken together, our data indicate that vaccination with Ii-E6 DNA with PADRE replacing the CLIP region is capable of enhancing the E6-specific CD8+ T-cell immune response generated by the Ii-E6 DNA. Thus, Ii-PADRE-E6 represents a novel DNA vaccine for the treatment of HPV-associated head and neck cancer and other HPV-associated malignancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981112"}
{"pmid": "20981116", "title": "Chronic kidney disease: the effect of CKD therapies on serum potassium levels.", "content": "Chronic kidney disease: the effect of CKD therapies on serum potassium levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981116"}
{"pmid": "20981114", "title": "Spatial organization of intestinal microbiota in the mouse ascending colon.", "content": "Spatial organization of intestinal microbiota in the mouse ascending colon. Complex microbial populations are organized in relation to their environment. In the intestine, the inner lining (mucosa) is a potential focal point for such organization. The proximal murine colon contains mucosal folds that are known to be associated with morphologically distinct microbes. To identify these microbes, we used the technique of laser capture microdissection (LCM) to sample microbes associated with these folds (interfold region) and within the central lumen (digesta region). Using 16S rRNA gene tag pyrosequencing, we found that microbes in the interfold region were highly enriched for the phylum Firmicutes and, more specifically, for the families Lachnospiraceae and Ruminococcaceae. Other families such as Bacteroidaceae, Enterococcaceae and Lactobacillaceae were all enriched in the digesta region. This high-resolution system to capture and examine spatial organization of intestinal microbes should facilitate microbial analysis in other mouse models, furthering our understanding of host-microbial interactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981114"}
{"pmid": "20981108", "title": "The effectiveness of sildenafil citrate in patients with erectile dysfunction and lower urinary system symptoms and the significance of asymptomatic inflammatory prostatitis.", "content": "The effectiveness of sildenafil citrate in patients with erectile dysfunction and lower urinary system symptoms and the significance of asymptomatic inflammatory prostatitis. We evaluated the effectiveness of sildenafil citrate on lower urinary system symptoms (LUTS) by using symptom score scales. We also evaluated whether or not the presence of asymptomatic inflammatory prostatitis had an effect on the alteration in the symptom scores. A total of 36 male patients were included in the study. For all the cases, 'International Prostate Symptom Score' (IPSS), 'National Health Institute Chronic Prostatitis Symptom Index' (NIH-CPSI) and 'International Index of Erectile Function' (IIEF-5) were investigated and the scores were calculated in the first visit. Sildenafil citrate was given for 30 days and at the second visit IPSS, NIH-CPSI and IIEF-5 scores were once more analyzed. Afterwards, the alterations of the scores between visits were statistically compared. Mean age of the 36 cases included in the study was 59.03±1.35. When the alterations in parameters of first visit and second visit were evaluated, we found a statistically significant increase in IIEF-5 and a statistically significant decrease in IPSS, IPSS-QOL (Quality of Life). In addition, when the cases were divided into two groups with and without asymptomatic inflammatory prostatitis, in the cases with asymptomatic inflammatory prostatitis, sildenafil citrate caused improvement only in ED, but had no effect on LUTS. Sildenafil citrate use in cases with LUTS and ED has an improving effect on LUTS as well as ED. However, in cases with asymptomatic inflammatory prostatitis, sildenafil citrate did not lead to an improvement in LUTS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981108"}
{"pmid": "20981115", "title": "Recovery of methanotrophs from disturbance: population dynamics, evenness and functioning.", "content": "Recovery of methanotrophs from disturbance: population dynamics, evenness and functioning. Biodiversity is claimed to be essential for ecosystem functioning, but is threatened by anthropogenic disturbances. Prokaryotes have been assumed to be functionally redundant and virtually inextinguishable. However, recent work indicates that microbes may well be sensitive to environmental disturbance. Focusing on methane-oxidizing bacteria as model organisms, we simulated disturbance-induced mortality by mixing native with sterilized paddy soil in two ratios, 1:4 and 1:40, representing moderate and severe die-offs. Disturbed microcosms were compared with an untreated control. Recovery of activity and populations was followed over 4 months by methane uptake measurements, pmoA-qPCR, pmoA-based terminal restriction fragment length polymorphism and a pmoA-based diagnostic microarray. Diversity and evenness of methanotrophs decreased in disturbed microcosms, but functioning was not compromised. We consistently observed distinctive temporal shifts between type I and type II methanotrophs, and a rapid population growth leading to even higher cell numbers comparing disturbed microcosms with the control. Overcompensating mortality suggested that population size in the control was limited by competition with other bacteria. Overall, methanotrophs showed a remarkable ability to compensate for die-offs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981115"}
{"pmid": "20981113", "title": "Immune responses to adeno-associated virus type 2 encoding channelrhodopsin-2 in a genetically blind rat model for gene therapy.", "content": "Immune responses to adeno-associated virus type 2 encoding channelrhodopsin-2 in a genetically blind rat model for gene therapy. We had previously reported that transduction of the channelrhodopsin-2 (ChR2) gene into retinal ganglion cells restores visual function in genetically blind, dystrophic Royal College of Surgeons (RCS) rats. In this study, we attempted to reveal the safety and influence of exogenous ChR2 gene expression. Adeno-associated virus (AAV) type 2 encoding ChR2 fused to Venus (rAAV-ChR2V) was administered by intra-vitreous injection to dystrophic RCS rats. However, rAAV-ChR2 gene expression was detected in non-target organs (intestine, lung and heart) in some cases. ChR2 function, monitored by recording visually evoked potentials, was stable across the observation period (64 weeks). No change in retinal histology and no inflammatory marker of leucocyte adhesion in the retinal vasculature were observed. Although antibodies to rAAV (0.01-12.21 μg ml(-1)) and ChR2 (0-4.77 μg ml(-1)) were detected, their levels were too low for rejection. T-lymphocyte analysis revealed recognition by T cells and a transient inflammation-like immune reaction only until 1 month after the rAAV-ChR2V injection. In conclusion, ChR2, which originates from Chlamydomonas reinhardtii, can be expressed without immunologically harmful reactions in vivo. These findings will help studies of ChR2 gene transfer to restore vision in progressed retinitis pigmentosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981113"}
{"pmid": "20981117", "title": "Acute kidney injury: kidney injury after contrast media: marker or mediator?", "content": "Acute kidney injury: kidney injury after contrast media: marker or mediator?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981117"}
{"pmid": "20981118", "title": "Chronic kidney disease: implications of the AURORA and JUPITER results.", "content": "Chronic kidney disease: implications of the AURORA and JUPITER results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981118"}
{"pmid": "20981119", "title": "Pathology: Oxford IgA nephropathy classification: valid for children?", "content": "Pathology: Oxford IgA nephropathy classification: valid for children?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981119"}
{"pmid": "20981120", "title": "Transplantation: can sirolimus prevent skin cancer in transplant recipients?", "content": "Transplantation: can sirolimus prevent skin cancer in transplant recipients?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981120"}
{"pmid": "20981121", "title": "Acute kidney injury: defining prerenal azotemia in clinical practice and research.", "content": "Acute kidney injury: defining prerenal azotemia in clinical practice and research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981121"}
{"pmid": "20981123", "title": "Genetics: How to validate a breast cancer prognostic signature.", "content": "Genetics: How to validate a breast cancer prognostic signature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981123"}
{"pmid": "20981122", "title": "Chemotherapy: Effectiveness of adjuvant chemotherapy for resected NSCLC.", "content": "Chemotherapy: Effectiveness of adjuvant chemotherapy for resected NSCLC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981122"}
{"pmid": "20981124", "title": "Radiotherapy: Accelerated radiotherapy for HNSCC in developing countries.", "content": "Radiotherapy: Accelerated radiotherapy for HNSCC in developing countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981124"}
{"pmid": "20981125", "title": "Targeted therapies: Tyrosine-kinase inhibitors--new standard for NSCLC therapy.", "content": "Targeted therapies: Tyrosine-kinase inhibitors--new standard for NSCLC therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981125"}
{"pmid": "20981126", "title": "Chemotherapy: Lo and behold, a role for lomustine in acute myeloid leukemia?", "content": "Chemotherapy: Lo and behold, a role for lomustine in acute myeloid leukemia?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981126"}
{"pmid": "20981128", "title": "Clinical utility of image-guided peritoneal and omental biopsy.", "content": "Clinical utility of image-guided peritoneal and omental biopsy. Image-guided core biopsy of the omentum and peritoneum was described a decade ago and has since been validated in a number of large studies as a safe and effective means of providing a tissue diagnosis in patients with undiagnosed peritoneal disease. Some studies have addressed its ability for determining whether peritoneal infiltration and/or omental masses in patients with prior malignancy represent recurrent disease or a new disease process. Others have focused on the specific issue of women suspected to have advanced peritoneal carcinomatosis from ovarian or primary peritoneal cancer where the primary management of the patient is directed by the tissue diagnosis. The initial management of many of these women, especially those with advanced disease or substantial comorbidity, is with primary chemotherapy. With current clinical trials for ovarian cancer directed to specific morphological subtypes of the disease, image-guided core biopsy offers a rapid and well tolerated nonsurgical means of providing this information. In this Review, we discuss the technique and its clinical applications, and critically examine the currently available alternative options.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981128"}
{"pmid": "20981130", "title": "Sudden infant death syndrome and left ventricular hypertrabeculation-hidden arrhythmogenic entity?", "content": "Sudden infant death syndrome and left ventricular hypertrabeculation-hidden arrhythmogenic entity? Left ventricular noncompaction/hypertrabeculation is a condition which is characterized by a highly trabeculated, \"spongy\" myocardium.It can present at any age with heart failure, arrhythmia and/or thromboembolic events.A wide variety of mutations have been found to be a cause of hypertrabeculation and it is possible that there is a continuum of hypertrophic cardiomyopathy, dilated cardiomyopathy and hypertrabeculation/noncompaction.We present a case of left ventricular hypertrabeculation which presented as sudden infant death syndrome and we propose that this entity may be a hidden cause of arrhythmic death in some infants presenting as sudden infant death syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981130"}
{"pmid": "20981131", "title": "The Double U Wave-Should the Electrocardiogram be Interpreted Echocardiographically?", "content": "The Double U Wave-Should the Electrocardiogram be Interpreted Echocardiographically? The U wave is still an electrocardiographic deflection of enigmatic origin. Numerous hypotheses on its origin have been formulated, but to date none has been conclusively proven. Recently, a report described the first case of bifid (or notched) U waves. Until then this phenomenon has only been described in the T wave. This is the first report of double U waves-two separate deflections, ascribed to an accessory papillary muscle. The presence of a double U wave will be associated with an accessory papillary muscle (s). This is a retrospective analysis of 4729 patient files of patients who were evaluated at a cardiology practice. The 12-lead surface electrocardiogram was evaluated for the possible presence of a double U wave. In cases where a double U wave was found, the transthoracic echocardiogram was then scrutinized for the presence of an accessory papillary muscle. A total of 3 cases of a double U wave were found. In every case an accessory papillary muscle was clearly seen on the transthoracic echocardiogram. A double U wave is a new variant of an old electrocardiographic deflection of enigmatic origin. This variant may be associated with an accessory papillary muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981131"}
{"pmid": "20981132", "title": "Expression of toll-like receptor 4, tumor necrosis factor- alpha, matrix metalloproteinase-9 and effects of benazepril in patients with acute coronary syndromes.", "content": "Expression of toll-like receptor 4, tumor necrosis factor- alpha, matrix metalloproteinase-9 and effects of benazepril in patients with acute coronary syndromes. The study aims to explore the relationship between expressions of toll-like receptor 4 (TLR4) on peripheral blood monocytes, serum tumor necrosis factor-alpha (TNF-α) and matrix metalloproteinase-9 (MMP-9) in patients with acute coronary syndromes(ACS), and to investigate the possible mechanisms of Benazepril stabilizing atherosclerosis plaques. 70 patients selected were randomly divided into Benazepril treatment group (35 patients) and regular treatment group (35 patients). Meanwhile, Stable angina pectoris (SAP) group of 32 patients and control group of 22 patients were also set up. With the help of flow-cytometry, expressions of TLR4 on peripheral blood monocytes of the four groups were analyzed and compared to show differences, correlations and changes of the above mentioned indicators. The concentration of TNF-α and MMP-9 in serum were measured by enzyme linked immunosorbent assay (ELISA). (1) Expressions of TLR4, levels of TNF-α and MMP-9 were increased and the rate was rising from the control group, to SAP group and then to ACS group. All these indicators in ACS group are significantly higher than those in other groups (P < 0.05). (ACS versus SAP, control; all (P < 0.05). (2) Multi-linear regression analysis indicates that there was a positive correlation between the expression level of TLR4 and serum levels of TNF-α and MMP-9 in patients with ACS (P < 0.01). (3) There is no significant differences between the expression level of TLR4 and serum levels of TNF-α and MMP-9 in Benazepril treatment group and regular treatment group before treatment (P > 0.05) while they all fell after treatment (P < 0.05). In addition, all the indicators decreased more greatly than the regular treatment group. TLR4 on peripheral blood monocytes and serum TNF-α and MMP-9 in patients with coronary arteriosclerosis disease may be effective markers of the vulnerable plaque. Benazepril can inhibit over-expression of TLR4 and reduce serum levels of TNF-α and MMP-9, thus stabilize the vulnerable plaques and improve the condition of the patients with ACS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981132"}
{"pmid": "20981127", "title": "Targeted therapies: Molecular selection for 'smart' study design in lung cancer.", "content": "Targeted therapies: Molecular selection for 'smart' study design in lung cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981127"}
{"pmid": "20981134", "title": "Paclitaxel as neoadjuvant therapy for high grade angiosarcoma of the spleen: a brief report and literature review.", "content": "Paclitaxel as neoadjuvant therapy for high grade angiosarcoma of the spleen: a brief report and literature review. Splenic angiosarcoma is a rare tumor with only a few cases reported in the literature. Surgical resection offers the best chance of cure for this aggressive neoplasm but is often precluded by infiltration of the tumor to surrounding critical structures. We report a case of a locally advanced angiosarcoma rendered operable by treatment with Paclitaxel monotherapy. A 69 year old female presented with a high grade splenic angiosarcoma, considered inoperable due to the extent of local spread. She received three cycles of single agent Paclitaxel and underwent a successful resection of the tumor. Chemotherapy options for splenic angiosarcoma are not well studied. Paclitaxel as monotherapy is a useful therapeutic option in down staging tumors, facilitating surgical resection and merits further study in clinical trials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981134"}
{"pmid": "20981133", "title": "Pazopanib for the treatment of patients with advanced renal cell carcinoma.", "content": "Pazopanib for the treatment of patients with advanced renal cell carcinoma. Dramatic advances in the care of patients with advanced renal cell carcinoma have occurred over the last ten years, including insights into the molecular pathogenesis of this disease, that have now been translated into paradigm-changing therapeutic strategies. Elucidating the importance of signaling cascades related to angiogenesis is notable among these achievements. Pazopanib is a novel small molecule tyrosine kinase inhibitor that targets VEGFR-1, -2, and -3; PDGFR-α, PDGFR-β; and c-kit tyrosine kinases. This agent exhibits a distinct pharmacokinetic profile as well as toxicity profile compared to other agents in the class of VEGF signaling pathway inhibitors. This review will discuss the scientific rationale for the development of pazopanib, as well as preclinical and clinical trials that led to approval of pazopanib for patients with advanced renal cell carcinoma. The most recent information, including data from 2010 national meeting of the American Society of Clinical Oncology, and the design of ongoing Phase III trials, will be discussed. Finally, an algorithm utilizing Level I evidence for the treatment of patients with this disease will be proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981133"}
{"pmid": "20981135", "title": "HO1 mRNA and Protein do not Change in Parallel in Bronchial Biopsies of Patients After Long Term Exposure to Sulfur Mustard.", "content": "HO1 mRNA and Protein do not Change in Parallel in Bronchial Biopsies of Patients After Long Term Exposure to Sulfur Mustard. Sulfur mustard (SM), is an alkylating agent and has been emerged as a chemical weapon in various battlefields. More recently, SM was employed in the Iraq conflict against Iranian military forces and civilians. Nowadays there are more than 40,000 people suffering from pulmonary lesions special chronic obstructive pulmonary disease (COPD) due to mustard gas in Iran. SM causes the endogenous production of reactive oxygen species (ROS).Heme oxygenases (HOs) are the rate-limiting enzyme for heme metabolism. Numerous studies have confirmed that HOs are concerned in diverse biological processes such as anti-oxidation.The present study was undertaken to consider the regulation of HO-1 and HO-2 n the human airway wall, and to suggest a probable role that HOs may play in cellular defense against oxidative stress due to SM.In this research ten unexposed SM individuals and twenty SM exposed patients were included. Evaluation of HO-1& HO -2 expressions in unexposed and SM exposed patients samples was performed by semiquantitative RT-PCR, real-time RT-PCR and Immunohistochemistry analysis.While unexposed SM samples expressed same levels of HOs, expression level of HO-1 was upregulated about 3.58 ± 1.93 folds in SM exposed patients in comparison with unexposed ones, we could not find any difference in expression of HO-2 n two groups. In contrast, Immunohistochemistry results showed negative HO-1 protein expression in SM injured patients.Our results revealed that HO1 may plays an important role in cellular protection against oxidative stress due to mustard gas toxicity in airway wall of SM exposed patients at mRNA level, but translational modifications might cause decrease in the amount of HO1 protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981135"}
{"pmid": "20981136", "title": "The effect of the gravitation of the moon on frequency of births.", "content": "The effect of the gravitation of the moon on frequency of births. The purpose of this study was to examine the influence of the gravitation of the Moon on the frequency of births in Kyoto, Japan. A retrospective cohort analysis of 1007 consecutive births without the use of the induction agents was conducted on a population of births in a private midwife hospital from January, 1966 to December, 2000. There was a significant increase in the cases of births, when the gravitation of the Moon to the Earth was less than 31.5 N. Results of this study suggest that the gravitation of the Moon has an influence on the frequency of births.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981136"}
{"pmid": "20981138", "title": "BeadDataPackR: A Tool to Facilitate the Sharing of Raw Data from Illumina BeadArray Studies.", "content": "BeadDataPackR: A Tool to Facilitate the Sharing of Raw Data from Illumina BeadArray Studies. Microarray technologies have been an increasingly important tool in cancer research in the last decade, and a number of initiatives have sought to stress the importance of the provision and sharing of raw microarray data. Illumina BeadArrays provide a particular problem in this regard, as their random construction simultaneously adds value to analysis of the raw data and obstructs the sharing of those data.We present a compression scheme for raw Illumina BeadArray data, designed to ease the burdens of sharing and storing such data, that is implemented in the BeadDataPackR BioConductor package (http://bioconductor.org/packages/release/bioc/html/BeadDataPackR.html). It offers two key advantages over off-the-peg compression tools. First it uses knowledge of the data formats to achieve greater compression than other approaches, and second it does not need to be decompressed for analysis, but rather the values held within can be directly accessed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981138"}
{"pmid": "20981137", "title": "Heterogeneity Between Ducts of the Same Nuclear Grade Involved by Duct Carcinoma In Situ (DCIS) of the Breast.", "content": "Heterogeneity Between Ducts of the Same Nuclear Grade Involved by Duct Carcinoma In Situ (DCIS) of the Breast. Nuclear grade of breast DCIS is considered during patient management decision-making although it may have only a modest prognostic association with therapeutic outcome. We hypothesized that visual inspection may miss substantive differences in nuclei classified as having the same nuclear grade. To test this hypothesis, we measured subvisual nuclear features by quantitative image cytometry for nuclei with the same grade, and tested for statistical differences in these features. EXPERIMENTAL DESIGN AND STATISTICAL ANALYSIS: Thirty-nine nuclear digital image features of about 100 nuclei were measured in digital images of H&E stained slides of 81 breast biopsy specimens. One field with at least 5 ducts was evaluated for each patient. We compared features of nuclei with the same grade in multiple ducts of the same patient with ANOVA (or Welch test), and compared features of nuclei with the same grade in two ducts of different patients using 2-sided t-tests (P ≤ 0.05). Also, we compared image features for nuclei in patients with single grade to those with the same grade in patients with multiple grades using t-tests. Statistically significant differences were detected in nuclear features between ducts with the same nuclear grade, both in different ducts of the same patient, and between ducts in different patients with DCIS of more than one grade. Nuclei in ducts visually described as having the same nuclear grade had significantly different subvisual digital image features. These subvisual differences may be considered additional manifestations of heterogeneity over and above differences that can be observed microscopically. This heterogeneity may explain the inconsistency of nuclear grading as a prognostic factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981137"}
{"pmid": "20981139", "title": "Assessment of mRNA and microRNA Stabilization in Peripheral Human Blood for Multicenter Studies and Biobanks.", "content": "Assessment of mRNA and microRNA Stabilization in Peripheral Human Blood for Multicenter Studies and Biobanks. In this study we evaluate the suitability of two methods of RNA conservation in blood samples, PAXgene and RNAlater, in combination with variable shipping conditions for their application in multicenter studies and biobanking. RNA yield, integrity, and purity as well as levels of selected mRNA and microRNA species were analyzed in peripheral human blood samples stabilized by PAXgene or RNAlater and shipped on dry ice or at ambient temperatures from the study centers to the central analysis laboratory. Both examined systems were clearly appropriate for RNA stabilization in human blood independently of the shipping conditions. The isolated RNA is characterized by good quantity and quality and well suited for downstream applications like quantitative RT-PCR analysis of mRNA and microRNA. Superior yield and integrity values were received using RNAlater. It would be reasonable to consider the production and approval of blood collection tubes prefilled with RNAlater to facilitate the use of this excellent RNA stabilization system in large studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981139"}
{"pmid": "20981141", "title": "Recovery of Visual Function in a Patient with an Onodi Cell Mucocele Compressive Optic Neuropathy Who Had a 5-Week Interval between Onset and Surgical Intervention: A Case Report.", "content": "Recovery of Visual Function in a Patient with an Onodi Cell Mucocele Compressive Optic Neuropathy Who Had a 5-Week Interval between Onset and Surgical Intervention: A Case Report. Purpose. To report on a patient with compressive optic neuropathy secondary to an Onodi cell mucocele, who fully recovered visual function following surgery. Method. Case report. Results. A 28-year-old male was admitted with a right visual acuity of 20/100 following treatment for an initial diagnosis of optic neuritis. Subsequent examination suggested compressive optic neuropathy, and neuroimaging confirmed the presence of an Onodi mucocele compressing the optic nerve. The patient underwent a right endonasal sphenoethmoidectomy with decompression 5 weeks after the initial onset of symptoms. Three weeks following surgery, the visual acuity was 20/20, and there was complete resolution of the visual field defect, which has remained stable at 1 year. Conclusion. Onodi cell mucocele should be included in the differential diagnosis of a young patient with compressive optic neuropathy. Surgical decompression should be considered even when symptoms have been present for over a month.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981141"}
{"pmid": "20981140", "title": "Factors influencing the one- and two-year growth response in children treated with growth hormone: analysis from an observational study.", "content": "Factors influencing the one- and two-year growth response in children treated with growth hormone: analysis from an observational study. To assess gender-, pubertal-, age-related differences in change from baseline height standard deviation score (ΔHSDS), data from 5,797 growth hormone (GH) naïve pediatric patients (<18 years) with growth hormone deficiency (GHD), multiple pituitary hormone deficiency (MPHD), Turner syndrome (TS), small for gestational age (SGA), Noonan syndrome (NS), and idiopathic short stature (ISS) were obtained from the ANSWER (American Norditropin Studies: Web-enabled Research) Program registry. For patients with SGA, ΔHSDS at year 1 was significantly greater for males versus females (P = .016), but no other gender differences were observed. For patients with GHD, ΔHSDS was greater in prepubertal than in pubertal patients. Younger patients for both genders (<11 years for boys; <10 years for girls) showed a greater ΔHSDS (P < .05 for GHD, MPHD, and ISS). Overall, positive ΔHSDSs were observed in all patients, with greater growth responses in younger prepubertal children, emphasizing the importance of starting GH treatment early.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981140"}
{"pmid": "20981142", "title": "Therapeutic Antibodies Targeting CSF1 Impede Macrophage Recruitment in a Xenograft Model of Tenosynovial Giant Cell Tumor.", "content": "Therapeutic Antibodies Targeting CSF1 Impede Macrophage Recruitment in a Xenograft Model of Tenosynovial Giant Cell Tumor. Tenosynovial giant cell tumor is a neoplastic disease of joints that can cause severe morbidity. Recurrences are common following local therapy, and no effective medical therapy currently exists. Recent work has demonstrated that all cases overexpress macrophage colony-stimulating factor (CSF1), usually as a consequence of an activating gene translocation, resulting in an influx of macrophages that form the bulk of the tumor. New anti-CSF1 drugs have been developed; however there are no preclinical models suitable for evaluation of drug benefits in this disease. In this paper, we describe a novel renal subcapsular xenograft model of tenosynovial giant cell tumor. Using this model, we demonstrate that an anti-CSF1 monoclonal antibody significantly inhibits host macrophage infiltration into this tumor. The results from this model support clinical trials of equivalent humanized agents and anti-CSF1R small molecule drugs in cases of tenosynovial giant cell tumor refractory to conventional local therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981142"}
{"pmid": "20981143", "title": "Sex chromosome evolution in amniotes: applications for bacterial artificial chromosome libraries.", "content": "Sex chromosome evolution in amniotes: applications for bacterial artificial chromosome libraries. Variability among sex chromosome pairs in amniotes denotes a dynamic history. Since amniotes diverged from a common ancestor, their sex chromosome pairs and, more broadly, sex-determining mechanisms have changed reversibly and frequently. These changes have been studied and characterized through the use of many tools and experimental approaches but perhaps most effectively through applications for bacterial artificial chromosome (BAC) libraries. Individual BAC clones carry 100-200 kb of sequence from one individual of a target species that can be isolated by screening, mapped onto karyotypes, and sequenced. With these techniques, researchers have identified differences and similarities in sex chromosome content and organization across amniotes and have addressed hypotheses regarding the frequency and direction of past changes. Here, we review studies of sex chromosome evolution in amniotes and the ways in which the field of research has been affected by the advent of BAC libraries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981143"}
{"pmid": "20981144", "title": "Activation of PPARs α, β/δ, and γ Impairs TGF-β1-Induced Collagens' Production and Modulates the TIMP-1/MMPs Balance in Three-Dimensional Cultured Chondrocytes.", "content": "Activation of PPARs α, β/δ, and γ Impairs TGF-β1-Induced Collagens' Production and Modulates the TIMP-1/MMPs Balance in Three-Dimensional Cultured Chondrocytes. Background and Purpose. We investigated the potency of Peroxisome Proliferators-Activated Receptors (PPARs) α, β/δ, and γ agonists to modulate Transforming Growth Factor-β1 (TGF-β1-) induced collagen production or changes in Tissue Inhibitor of Matrix Metalloproteinase- (TIMP-) 1/Matrix Metalloproteinase (MMP) balance in rat chondrocytes embedded in alginate beads. Experimental Approach. Collagen production was evaluated by quantitative Sirius red staining, while TIMP-1 protein levels and global MMP (-1, -2, -3, -7, and -9) or specific MMP-13 activities were measured by ELISA and fluorigenic assays in culture media, respectively. Levels of mRNA for type II collagen, TIMP-1, and MMP-3 & 13 were quantified by real-time PCR. Key Results. TGF-β1 increased collagen deposition and type II collagen mRNA levels, while inducing TIMP-1 mRNA and protein expression. In contrast, it decreased global MMP or specific MMP-13 activities, while decreasing MMP-3 or MMP-13 mRNA levels. PPAR agonists reduced most of the effects of TGF-β1 on changes in collagen metabolism and TIMP-1/MMP balance in rat in a PPAR-dependent manner, excepted for Wy14643 on MMP activities. Conclusions and Implications. PPAR agonists reduce TGF-β1-modulated ECM turnover and inhibit chondrocyte activities crucial for collagen biosynthesis, and display a different inhibitory profile depending on selectivity for PPAR isotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981144"}
{"pmid": "20981146", "title": "Biochemical signatures of doppel protein in human astrocytomas to support prediction in tumor malignancy.", "content": "Biochemical signatures of doppel protein in human astrocytomas to support prediction in tumor malignancy. Doppel (Dpl) is a membrane-bound glycoprotein mainly expressed in the testis of adult healthy people. It is generally absent in the central nervous system, but its coding gene sequence is ectopically expressed in astrocytoma specimens and in derived cell lines. In this paper, we investigated the expression and the biochemical features of Dpl in a panel of 49 astrocytoma specimens of different WHO malignancy grades. As a result, Dpl was expressed in the majority of the investigated specimens (86%), also including low grade samples. Importantly, Dpl exhibited different cellular localizations and altered glycan moieties composition, depending on the tumor grade. Most low-grade astrocytomas (83%) showed a membrane-bound Dpl, like human healthy testis tissue, whereas the majority of high-grade astrocytomas (75%) displayed a cytosolic Dpl. Deglycosylation studies with N-glycosidase F and/or neuraminidase highlighted defective glycan moieties and an unexpected loss of sialic acid. To find associations between glial tumor progression and Dpl biochemical features, predictive bioinformatics approaches were produced. In particular, Decision tree and Nomogram analysis showed well-defined Dpl-based criteria that separately clustered low-and high-grade astrocytomas. Taken together, these findings show that in astrocytomas, Dpl undergoes different molecular processes that might constitute additional helpful tools to characterize the glial tumor progression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981146"}
{"pmid": "20981147", "title": "Effects of clofibrate on salt loading-induced hypertension in rats.", "content": "Effects of clofibrate on salt loading-induced hypertension in rats. The effects of clofibrate on the hemodynamic and renal manifestations of increased saline intake were analyzed. Four groups of male Wistar rats were treated for five weeks: control, clofibrate (240 mg/kg/day), salt (2% via drinking water), and salt + clofibrate. Body weight, systolic blood pressure (SBP), and heart rate (HR) were recorded weekly. Finally, SBP, HR, and morphologic, metabolic, plasma, and renal variables were measured. Salt increased SBP, HR, urinary isoprostanes, NOx, ET, vasopressin and proteinuria and reduced plasma free T(4) (FT(4)) and tissue FT(4) and FT(3) versus control rats. Clofibrate prevented the increase in SBP produced by salt administration, reduced the sodium balance, and further reduced plasma and tissue thyroid hormone levels. However, clofibrate did not modify the relative cardiac mass, NOx, urinary ET, and vasopressin of saline-loaded rats. In conclusion, chronic clofibrate administration prevented the blood pressure elevation of salt-loaded rats by decreasing sodium balance and reducing thyroid hormone levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981147"}
{"pmid": "20981149", "title": "Isolation of specific clones from nonarrayed BAC libraries through homologous recombination.", "content": "Isolation of specific clones from nonarrayed BAC libraries through homologous recombination. We have developed a new approach to screen bacterial artificial chromosome (BAC) libraries by recombination selection. To test this method, we constructed an orangutan BAC library using an E. coli strain (DY380) with temperature inducible homologous recombination (HR) capability. We amplified one library segment, induced HR at 42°C to make it recombination proficient, and prepared electrocompetent cells for transformation with a kanamycin cassette to target sequences in the orangutan genome through terminal recombineering homologies. Kanamycin-resistant colonies were tested for the presence of BACs containing the targeted genes by the use of a PCR-assay to confirm the presence of the kanamycin insertion. The results indicate that this is an effective approach for screening clones. The advantage of recombination screening is that it avoids the high costs associated with the preparation, screening, and archival storage of arrayed BAC libraries. In addition, the screening can be conceivably combined with genetic engineering to create knockout and reporter constructs for functional studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981149"}
{"pmid": "20981148", "title": "The Relationship between Physical Activity and Bone during Adolescence Differs according to Sex and Biological Maturity.", "content": "The Relationship between Physical Activity and Bone during Adolescence Differs according to Sex and Biological Maturity. This study examines the relationships between bone mass, physical activity, and maturational status in healthy adolescent boys and girls. Methods. Ninety-nine early high-school (Year 9) students were recruited. Physical activity and other lifestyle habits were recorded via questionnaire. Anthropometrics, muscle power, calcaneal broadband ultrasound attenuation (BUA), bone mineral content (BMC), and lean tissue mass were measured. Maturity was determined by Tanner stage and estimated age of peak height velocity (APHV). Results. Boys had greater APHV, weight, height, muscle power, and dietary calcium than girls (P < .05). Boys exhibited greater femoral neck BMC and trochanteric BMC while girls had higher BUA and spine BMAD (P < .05). Physical activity and vertical jump predicted BMAD and BUA most strongly for boys whereas years from APHV were the strongest predictor for girls. Conclusion. Sex-specific relationships exist between physical activity, maturity and bone mass during adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981148"}
{"pmid": "20981150", "title": "Revisiting estrogen: efficacy and safety for postmenopausal bone health.", "content": "Revisiting estrogen: efficacy and safety for postmenopausal bone health. The rapid decline in endogenous estrogen production that occurs during menopause is associated with significant bone loss and increased risk for fragility fracture. While hormone therapy (HT) is an effective means to re-establish endogenous estrogen levels and reduce the risk of future fracture, its use can be accompanied by undesirable side effects such as stroke and breast cancer. In this paper, we revisit the issue of whether HT can be both safe and effective for the prevention of postmenopausal bone loss by examining standard and alternative doses and formulations of HT. The aim of this paper is to continue the dialogue regarding the benefits and controversies of HT with the goal of encouraging the dissemination of-up-to date evidence that may influence how HT is viewed and prescribed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981150"}
{"pmid": "20981145", "title": "Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems.", "content": "Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems. DNA is subjected to many endogenous and exogenous damages. All organisms have developed a complex network of DNA repair mechanisms. A variety of different DNA repair pathways have been reported: direct reversal, base excision repair, nucleotide excision repair, mismatch repair, and recombination repair pathways. Recent studies of the fundamental mechanisms for DNA repair processes have revealed a complexity beyond that initially expected, with inter- and intrapathway complementation as well as functional interactions between proteins involved in repair pathways. In this paper we give a broad overview of the whole DNA repair system and focus on the molecular basis of the repair machineries, particularly in Thermus thermophilus HB8.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981145"}
{"pmid": "20981153", "title": "Influence of Friction Resistance on Expression of Superelastic Properties of Initial NiTi Wires in \"Reduced Friction\" and Conventional Bracket Systems.", "content": "Influence of Friction Resistance on Expression of Superelastic Properties of Initial NiTi Wires in \"Reduced Friction\" and Conventional Bracket Systems. Objectives. The aim of this study was to assess the influence of resistance to sliding on expression of superelastic properties of NiTi wires. Methods and Materials. A three-point bending test was performed for 0.014 NiTi wire engaged in self-ligating (Damon, SmartClip, In-Ovation) and conventional brackets (Victory) ligated with regular and reduced friction modules (Slide). The wire was deflected in the buccal direction and allowed to straighten. The maximum load, unloading plateau and unloading capacity were registered. Results. The lowest activation load was required in the active self-ligating group (In-Ovation 2.2 ± 0.4 N) and reduced friction module group (Victory/Slide 2.9 ± 0.4 N), followed by the passive self-ligating systems (Damon 3.6 ± 0.7 N, SmartClip 3.7 ± 0.4 N). Higher activation load was obtained in the conventionally ligated group (Victory/module 4.5 ± 0.4 N). Unloading plateau phase with the load magnitude ranging from 1.27 ± 0.4 N (In-Ovation) to 1.627 ± 0.4 N (Slide) was distinct in all groups but one (Victory). Conclusions. Higher friction at flanking points reduces the net force delivered by the wire. Unloading plateau phase of NiTi load-deflection curve disappears in the conventionally ligated group thus indicating to an incomplete expression of NiTi superelastic properties. A rigid passive bracket clip amplifies resistance to sliding in an active configuration and produces a permanent deflection of the wire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981153"}
{"pmid": "20981152", "title": "A radiographic study on the associations of age and prevalence of vertebral fractures with abdominal aortic calcification in Japanese postmenopausal women and men.", "content": "A radiographic study on the associations of age and prevalence of vertebral fractures with abdominal aortic calcification in Japanese postmenopausal women and men. The purpose of the present study was to determine the associations of age and history of non- and low-traumatic fractures with the severity of abdominal aortic calcification in Japanese postmenopausal women and men. Four hundred and one Japanese persons (24 men and 377 postmenopausal women, mean age: 73.8 years) for whom thoracic and lumbar spine radiographs had been obtained to evaluate their posture prior to patient participation in a fall-prevention exercise program were enrolled. The associations of sex, age, history of hip fracture, prevalence of vertebral fracture, and spondylosis grade (the Nathan degree) with the severity of abdominal aortic calcification (length of calcification, as evaluated according to the number of vertebral bodies) were analyzed. Nine subjects (2.2%) had a history of hip fracture, and 221 (55.1%) had at least one prevalent vertebral fracture. Two hundred and sixty-seven subjects (66.6%) had first-degree spondylosis. Age and the number of prevalent vertebral fractures, but not sex, history of hip fracture, or spondylosis grade, were significantly associated with the severity of abdominal aortic calcification. The present study confirmed that age and the number of vertebral fractures were associated with the severity of abdominal aortic calcification in Japanese postmenopausal women and men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981152"}
{"pmid": "20981151", "title": "A 10-month physical activity intervention improves body composition in young black boys.", "content": "A 10-month physical activity intervention improves body composition in young black boys. Objective. To determine if a 10-month after-school physical activity (PA) intervention could prevent deleterious changes in body composition and cardiovascular (CV) fitness in young black boys. Methods. Following baseline measures, 106 boys (8-12 yrs) were randomized to either a control group or an intervention group, further divided into attenders (ATT) and nonattenders (NATT), participating in ≥60% or <60% of the intervention, respectively. The daily intervention consisted of skills development (25 min), vigorous PA (VPA, 35 min), and strengthening/stretching (20 min) components. Body composition was measured by dual-energy X-ray absorptiometry. Results. Following the intervention, the ATT exhibited an increase in moderate-to-vigorous PA and a significant reduction in BMI, fat mass, and %BF compared to the control group. A significant association among the intervention energy expenditure and changes in body composition and CV fitness was observed only in the ATT group. Conclusion. An after-school PA program of sufficient length and intensity can promote healthy changes in body composition and fitness levels in black boys who attend at least 3 days/week.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981151"}
{"pmid": "20981154", "title": "Biomechanical Response in Mandibular Bone due to Mastication Loading on 3-Unit Fixed Partial Dentures.", "content": "Biomechanical Response in Mandibular Bone due to Mastication Loading on 3-Unit Fixed Partial Dentures. An understanding of functional responses in oral bone is a crucial component of dental biomechanics. The purpose of this study was to investigate the potential biological remodelling response during mastication on the mandibular pre- and post-insertion of a fixed partial denture (FPD). A series of three-dimensional (3D) finite element analysis (FEA) models were presented pre- and postextraction to determine the biomechanical responses to masticatory loading in the anterior mandible. Equivalent strains were analysed at lingual/buccal and mesial/distal areas of the premolar to molar region and quantified to anticipate bone remodelling response. Mandibular bone incorporating an FPD experienced substantially greater stress/strain magnitudes than that prior to placement of fixed prosthodontics, which is suggestive of engagements of bone remodelling. The results suggest similar outcomes to those reported clinically. Developing a simulation reflecting the outcomes of restorative treatment can provide meaningful insight into restorative treatment planning, clinical outcomes, and fixed prosthodontics designs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981154"}
{"pmid": "20981155", "title": "Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment.", "content": "Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment. Thomas Hodgkin's and Samuel Wilks first recognized Hodgkin disease in the first half of the 19th century. Initially described as lymphogranulomatosis, it was later recognized to be a lymphoid neoplasm derived from B cells and was classified on the basis of its histopathological features. Hodgkin lymphomas are now regarded as encompassing two clearly defined entities according to the WHO classification: nodular lymphocyte-predominant Hodgkin Lymphoma (NLPHL) and classical Hodgkin Lymphoma (CHL). This paper focuses on the current knowledge about the biological features that characterize both NLPHL and CHL, highlighting those relevant to correct pathological diagnosis and those that might be associated with patient outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981155"}
{"pmid": "20981156", "title": "The effects of forodesine in murine and human multiple myeloma cells.", "content": "The effects of forodesine in murine and human multiple myeloma cells. Multiple myeloma (MM) is the second most commonly diagnosed hematological malignancy, characterized by a monoclonal proliferation of malignant cells in the bone marrow. Despite recent advances in treatment strategies, MM remains incurable and new therapeutical targets are needed. Recently forodesine, a purine nucleoside phosphorylase inhibitor, was found to induce apoptosis in leukemic cells of chronic lymphocytic leukemia patients by increasing the dGTP levels. We therefore tested whether forodesine was able to inhibit proliferation and/or induce apoptosis in both murine and human MM cells through a similar pathway. We found that after 48 hours of treatment with forodesine there was a slight dGTP increase in 5T33MM and RPMI-8226 MM cells associated with partial inhibition of proliferation and a limited induction of apoptosis. When investigating the pathways leading to cell cycle arrest and apoptosis, we observed an upregulation of p27, caspase 3, and BIM. We can conclude that forodesine has some effects on MM cells but not as impressive as the known effects in leukemic cells. Forodesine might be however potentiating towards other established cytotoxic drugs in MM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981156"}
{"pmid": "20981157", "title": "Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma.", "content": "Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma. Hodgkin's Lymphoma was incurable until the advent of effective therapeutic radiation around the first half of the 20th century. As survival rates improved, the long-term toxicities from radiotherapy began to emerge. This together with the availability of effective chemotherapy has encouraged a combined modality approach for early-staged disease and the omission of radiotherapy in advanced-staged disease. The differing toxicities of radiotherapy and chemotherapy has promoted ongoing research to identify the utility of each of these modalities in the modern management of Hodgkin's Lymphoma. This article will provide a critical review of the developments and indications for modern radiotherapy, in context with advances in chemotherapy, for the treatment of Hodgkin's Lymphoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981157"}
{"pmid": "20981158", "title": "The Role of Allogeneic Stem Cell Transplantation in Relapsed/Refractory Hodgkin's Lymphoma Patients.", "content": "The Role of Allogeneic Stem Cell Transplantation in Relapsed/Refractory Hodgkin's Lymphoma Patients. Despite the favorable prognosis of most patients with Hodgkin's Lymphoma (HL), 15-20% of patients remain refractory to chemoradiotherapy, and 20-40% experience relapses following autologous stem cell transplantation (SCT) being used as salvage approach in this situation. Long-term survival of only 20% was reported for patients who failed this option. As some authors suggested the presence of a graft versus HL effect, allogeneic SCT was introduced as a further option. Myeloablative strategies were reported to be able to achieve cure in some younger patients, but high nonrelapse mortality remains a problem. Reduced intensity conditioning, in turn, was found to be associated with high posttransplant relapse rates. As there is currently no standard in the management of HL patients who failed autologous SCT, we here review the literature on allogeneic stem cell transplantation in HL patients with a special focus on the outcomes and risk factors being reported in the largest studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981158"}
{"pmid": "20981159", "title": "Concentration-Dependent Protection by Ethanol Extract of Propolis against γ-Ray-Induced Chromosome Damage in Human Blood Lymphocytes.", "content": "Concentration-Dependent Protection by Ethanol Extract of Propolis against γ-Ray-Induced Chromosome Damage in Human Blood Lymphocytes. Radioprotection with natural products may be relevant to the mitigation of ionizing radiation-induced damage in mammalian systems; in this sense, propolis extracts have shown effects such as antioxidant, antitumoral, anti-inflammatory, and immunostimulant. We report for the first time a cytogenetic study to evaluate the radioprotective effect, in vitro, of propolis against radiation-induced chromosomal damage. Lymphocytes were cultured with increasing concentrations of ethanol extract of propolis (EEP), including 20, 40, 120, 250, 500, 750, 1000, and 2000 μg mL(-1) and then exposed to 2 Gy γ-rays. A significant and concentration-dependent decrease is observed in the frequency of chromosome aberrations in samples treated with EEP. The protection against the formation of dicentrics was concentration-dependent, with a maximum protection at 120 μg mL(-1) of EEP. The observed frequency of dicentrics is described as negative exponential function, indicating that the maximum protectible fraction of dicentrics is approximately 44%. Free radical scavenging and antioxidant activities are the mechanisms that these substances use to protect cells from ionizing radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981159"}
{"pmid": "20981160", "title": "A Randomized Controlled Exploratory Evaluation of Standardized Ayurvedic Formulations in Symptomatic Osteoarthritis Knees: A Government of India NMITLI Project.", "content": "A Randomized Controlled Exploratory Evaluation of Standardized Ayurvedic Formulations in Symptomatic Osteoarthritis Knees: A Government of India NMITLI Project. The multidisciplinary \"New Millennium Indian Technology Leadership Initiative\" Arthritis Project was undertaken to validate Ayurvedic medicines. Herbal formulations in popular use were selected by expert consensus and standardized using modern tools. Our clinical strategy evolved from simple exploratory evaluations to better powered statistically designed drug trials. The results of the first drug trial are presented here. Five oral formulations (coded A, B, C, D and E), with a common base of Zingiber officinale and Tinospora cordifolia with a maximum of four plant extracts, were evaluated; with placebo and glucosamine as controls. 245 patients suffering from symptomatic OA knees were randomized into seven arms (35 patients per arm) of a double blind, parallel efficacy, multicentric trial of sixteen weeks duration. The groups matched well at baseline. There were no differences for patient withdrawals (17.5%) or adverse events (AE) of mild nature. Intention-to-treat efficacy analysis, demonstrated no significant differences (P < .05) for pain (weight bearing) and WOMAC questionnaire (knee function); placebo response was high. Based on better pain relief, significant (P < .05) least analgesic consumption and improved knee status, \"C\" formulation was selected for further development. Controlled exploratory drug trials with multiple treatment arms may be used to economically evaluate several candidate standardized formulations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981160"}
{"pmid": "20981162", "title": "Gestational diabetes mellitus: why screen and how to diagnose.", "content": "Gestational diabetes mellitus: why screen and how to diagnose. Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. Women with GDM and their offspring have an increased risk of developing type 2 diabetes mellitus in the future. The global incidence of GDM is difficult to estimate, due to lack of uniform diagnostic criteria. Various diagnostic criteria have been proposed. The benefit of treating GDM has also been controversial. The clinical significance of treating maternal hyperglycemia was made evident in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study. The HAPO study demonstrated that there is a continuous association of maternal glucose levels with adverse pregnancy outcomes and served as the basis for a new set of diagnostic criteria, proposed in 2010 by the International Association of Diabetes and Pregnancy Groups (IADPSG). According to these criteria the diagnosis of GDM is made if there is at least one abnormal value (≥92, 180 and 153 mg/dl for fasting, one-hour and two-hour plasma glucose concentration respectively), after a 75 g oral glucose tolerance test (OGTT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981162"}
{"pmid": "20981161", "title": "Low-Frequency Electroacupuncture Improves Insulin Sensitivity in Obese Diabetic Mice through Activation of SIRT1/PGC-1α in Skeletal Muscle.", "content": "Low-Frequency Electroacupuncture Improves Insulin Sensitivity in Obese Diabetic Mice through Activation of SIRT1/PGC-1α in Skeletal Muscle. Electroacupuncture (EA) has been observed to reduce insulin resistance in obesity and diabetes. However, the biochemical mechanism underlying this effect remains unclear. This study investigated the effects of low-frequency EA on metabolic action in genetically obese and type 2 diabetic db/db mice. Nine-week-old db/m and db/db mice were randomly divided into four groups, namely, db/m, db/m + EA, db/db, and db/db + EA. db/m + EA and db/db + EA mice received 3-Hz electroacupuncture five times weekly for eight consecutive weeks. In db/db mice, EA tempered the increase in fasting blood glucose, food intake, and body mass and maintained insulin levels. In EA-treated db/db mice, improved insulin sensitivity was established through intraperitoneal insulin tolerance test. EA was likewise observed to decrease free fatty acid levels in db/db mice; it increased protein expression in skeletal muscle Sirtuin 1 (SIRT1) and induced gene expression of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), nuclear respiratory factor 1 (NRF1), and acyl-CoA oxidase (ACOX). These results indicated that EA offers a beneficial effect on insulin resistance in obese and diabetic db/db mice, at least partly, via stimulation of SIRT1/PGC-1α, thus resulting in improved insulin signal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981161"}
{"pmid": "20981164", "title": "Collagenous and non-collagenous biochemical markers of bone metastases from prostate cancer.", "content": "Collagenous and non-collagenous biochemical markers of bone metastases from prostate cancer. The importance of the bone microenvironment to the pathophysiology and morbidity associated with prostate cancer bone metastasis is becoming increasingly apparent. Significant alterations take place in the microenvironment of bone, which disturb the normal coupling that exists between bone resorption and bone formation. Consequently, a better understanding of the mechanisms that interact at the molecular level will definitely result in more effective therapy for patients with this devastating complication of prostatic carcinoma. This review will discuss the diagnostic and predictive implications of various collagenous and non-collagenous bone markers, along with the novel markers of osteoclastogenesis and other matrix enzymes such as metalloproteinases and growth factors responsible for the complex biochemical mechanisms that upregulate bone resorption/formation during the development of metastasis. Further prospective studies are needed to determine whether any of these markers measured longitudinally in prostate cancer patients without bone scan evidence of skeletal disease will ultimately predict those patients who will develop bone metastases from their malignancy. Nonetheless, from the clinical point of view it is important to know that these novel markers carry the potential to provide meaningful information for daily practice by using upper normal reference values as cut-offs for identifying patients with an increased risk of developing progressive bone disease or skeletal related events.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981164"}
{"pmid": "20981166", "title": "Long-term outcome after implantation of prosthetic disc nucleus device (PDN) in lumbar disc disease.", "content": "Long-term outcome after implantation of prosthetic disc nucleus device (PDN) in lumbar disc disease. The prosthetic disc nucleus (PDN) device offers an adjunct treatment for patients with degenerative disc disease and herniation, who necessitate surgical intervention, avoiding total-disc replacement or fusion. This prospective, clinical study aimed to gauge the long-term effectiveness of microdiscectomy followed by PDN implantation in relieving pain and improving functional status in patients with symptomatic degenerative lumbar disc disease and herniation. Ten patients with a) at least 6 months low back pain and/or sciatica resistant to conservative treatment and b) radiologically documented degenerative lumbar disc disease and herniation have been selected. Follow-up at 6 weeks, 3, 12, 48, and 96 months postoperatively included physical examination, radiological investigation (plain and dynamic radiographs and magnetic resonance imaging), and self-completion of outcome scales (visual analogue, Oswestry, and Prolo functional status). Short Form-36 version 2 Health Survey patient profile at 96 months completed the image of health related quality of life. Patients' mean follow-up was 100.6 months. Significant improvements in Oswestry, Prolo, and VAS scores were documented (p: 0.004 in all scales at 48 months). Generic health status was rated within the average lumbar disease population (46.36.8 for physical component summary and 45.29.6 for mental component summary). Lumbar spine range of motion (20.211.8 at 96 months) was restricted in relation to normal, but maintained considerable mobility. Treated disc height increased postoperatively (p:0.002) and its maintenance could also be documented in all cases. Disc height at the level above did not show any significant modification. All postoperative MRI showed a non-clinically significant high signal of end-plate on T2 sequences. Clinically relevant complications included one case of pulmonary thrombosis and one case of device extrusion, which was subsequently explanted. After implantation, most patients continue to enjoy significant pain relief, a considerable amount of mobility is conserved and the disease specific functional outcome is excellent and remains for long, although it could not be supported that the generic health related quality of life is that of the general population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981166"}
{"pmid": "20981163", "title": "P2X(7) receptor at the heart of disease.", "content": "P2X(7) receptor at the heart of disease. Purinergic signaling is a crucial component of disease whose pathophysiological basis is now well established. This review focuses on P2X(7), a unique bifunctional purinoreceptor that either opens a non selective cation channel or forms a large, cytolytic pore depending on agonist application and leading to membrane blebbing and to cell death either by necrosis or apoptosis.Activation of P2X(7) receptor has been shown to stimulate the release of multiple proinflammatory cytokines by activated macrophages, with the IL-1b to be the most extensively studied among them. These findings were verified by the use of knockout P2X(7) ((-/-)) mice.Update information coming from all fields of research implicate this receptor at the very heart of diseases such as rheumatoid arthritis, multiple sclerosis, depression, Alzheimer disease, and to kidney damage, in renal fibrosis and experimental nephritis.Clinical studies are currently underway with the newly developed selective antagonists for P2X(7) receptor, the results of which are eagerly anticipated. These studies together with data from in-vivo experiments with the P2X(7) knockout mice and in-vitro experiments will shed light in this exciting area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981163"}
{"pmid": "20981165", "title": "Screening for prostate cancer: a controversy or fact.", "content": "Screening for prostate cancer: a controversy or fact. Adenocarcinoma of the prostate is the most frequent malignancy in men and the second leading cause of death in the male population worldwide. The screening for prostate cancer allows early diagnosis of prostate malignancy before the individual presents with symptoms. The early stage of the disease is easier to manage by different therapeutic modalities. The aim of this review is to evaluate the reasons and facts for enthusiasm and positive approach towards the clinical decision about whether to screen or not male patients for early detection of prostate cancer. We performed a computerized MEDLINE search followed by a manual bibliographic review of cross-references. These reports were analyzed and the important findings were summarized. We analyzed the methods and schedule of screening, as well as advantages and disadvantages of the prostate cancer screening. There were more than a hundred studies on prostate cancer screening performed but only a few are eligible for a decisive conclusion concerning the prostate cancer screening issue. We reviewed the screening methods, the schedule of screening, the advantages and disadvantages of prostate cancer screening. The role for prostate cancer screening is not established yet. Definite proof of screening should be assumed as a decrease in the death rate of that cancer due to screening activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981165"}
{"pmid": "20981167", "title": "Homocysteine and its relationship to deep venous thrombosis in patients undergoing total knee or hip arthroplasty.", "content": "Homocysteine and its relationship to deep venous thrombosis in patients undergoing total knee or hip arthroplasty. Backround: The role of hyperhomocysteinemia as an independent risk factor for venous thrombosis after lower limb arthroplasty remains questionable. The objective of this study is to determine the relationship between hyperhomocysteinemia and postoperative thromboembolic events in patients undergoing total hip or knee arthroplasty. Between September 2004 and June 2006, we studied 172 patients (41 male and 131 female) with mean age 70.2 years (48-85). Total plasma homocysteine as well as other thrombophilic agents (proteinC, protein S, Antithrombin III, Lupus anticoagulants, APC-Resistance) were measured preoperatively. Duplex sonography was performed twice postoperatively, on the 7(th) day (+/-2) and on the 42th day (+/- 2). Spiral CT was performed when pulmonary embolism was suspected. Four patients developed deep venous thrombosis from which two developed pulmonary embolism. Only one of these four patients had high levels of total plasma homocysteine. Total plasma homocysteine does not seem to affect the development of deep venous thrombosis in patients undergoing total knee or hip arthroplasty and receive low molecular weight heparine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981167"}
{"pmid": "20981168", "title": "Correlation of depressive symptoms and olfactory dysfunction in patients on hemodialysis.", "content": "Correlation of depressive symptoms and olfactory dysfunction in patients on hemodialysis. A possible link between depression and olfactory dysfunction has been suggested in the literature, in research projects using the olfactory bulbectomy model. In human studies using a syndrome-oriented approach, such an association has not been reported consistently. The aim of the study was to test the association of olfactory dysfunction with depression using a symptom-oriented approach.Paients and methods: Twenty eight end-stage renal failure patients took part in this project. The patients olfactory identification ability was tested with the University of Pennsylvania Smell Identification Test (UPSIT). Immediately before olfactory testing, the subjects completed the Zung self-rating scale, which provides data on symptoms of depression in this group of patients. The mean value of the number of mistakes made in the olfactory identification ability (UPSIT test) by the total sample was 14.0±4.5, with a range 6-22. Half of the symptoms seem to bear an influence on the olfactory identification performance. Patients experiencing decreased libido and dissatisfaction exhibited significantly reduced olfactory function, as contrasted to those not experiencing these symptoms. The above results remain practically unaltered even after taking into account such probable confounding factors as age, sex, olfactory detection threshold and duration of illness. These findings support previous evidence indicating that olfactory dysfunction may be related to specific depressive symptoms in humans. The present findings also suggest that the symptom-oriented approach is an effective research tool for the elucidation of such clinical issues. The need for further research in this field is pointed out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981168"}
{"pmid": "20981169", "title": "Nutrition parameters as hemodialysis adequacy markers.", "content": "Nutrition parameters as hemodialysis adequacy markers. The nutritive status has significant role in improving the quality of life of dialysis' patients. The aim of this study was to find out if there is any correlation of the anthropometric parameters and markers of nutrition with the adequacy of HD. The investigation was organized as a clinical, cross sectional study. Demographic characteristics, co-morbid conditions, smoking, dialysis duration and blood pressure were recorded. Serum total protein, albumin, ferritin and blood-lipids were measured as biochemical markers of nutritional status.One hundred and forty patients, 82 (58.6%) male, and 58 (41.4%) female, 55±12.59 years, were dividied into two groups. Group A consisted of 44 patients (14 women and 30 men) received the recommended hemodialysis dose (Kt/V ≥ 1.2), while the Group B consisted of 96 patients (69 males and 27 females) received non-adequate hemodialysis dose (Kt/V < 1.2). Patients with adequate hemodialysis had been longer on dialysis in correlation with the group of patients with non-adequate hemodialysis (73 ± 56.4 vs. 44 ± 50.1 months; p: 0.004). Group A and group B presented significant differences in the number of leukocytes (p: 0.027), and hemoglobin (p: 0.047), potassium (p: 0.038) and C-reactive protein level (p: 0.048) as well as in serum total protein (69 ± 4.63 vs. 65 ± 5.74 g/L; p < 0.0001) and albumin (38 ± 2.99 vs. 29 ± 4.4 g/L; p: 0.047). Pearsons correlation of factors that may have impact on hemodialysis adequacy indicated a significant relation between serum total protein and the index of hemodialysis adequacy (r: 0.21; p: 0.0446). All investigated anthropometric parameters and protein status showed significantly higher values in patients with adequate hemodialysis quality (Group A). The Group B showed higher levels of CRP and lower values of hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981169"}
{"pmid": "20981172", "title": "First body fat percentiles for 607 children from Thessaloniki-Northern Greece.", "content": "First body fat percentiles for 607 children from Thessaloniki-Northern Greece. The purpose of this study was to establish for the first time reference curves for body fat levels in a Greek pediatric population aged 7-15y. Six hundred and seven (607) children randomly selected from 8 primary and secondary schools from Northern Greece. Percentage body fat was measured by bioelectrical impedance analysis and percentile curves were constructed using the LMS method. All children were measured twice in the morning and the mean number of the two measurements was considered as the percentage of body fat. The mean number of the percentage body fat for the age group (7-9) was 18.2 ± 5.1 and 18.4 ± 6.1 for boys and girls, respectively. In the second age group (10-12) the girls had higher mean fat levels than boys (22.6 ± 5.8 vs. 20.4 ± 6.2). This increase was continued also in the third age group (13-15) with the girls having higher mean body fat levels (24.2 ± 5.5 vs. 17 ± 5.9). The 85th and 95th percentiles represented the cut-off point for overweight and obesity and it was (26.3, 33.0 and 28.9%) and (34.0, 38.2 and 38.1) for boys for the three age groups (7-9, 10-12 and 13-15), respectively. On the other hand, the girls had higher 85th and 95th percentiles for the same age group (7-9, 10-12, 13-15y) and it was (34.5, 32.9 and 33.6%) and (39.0, 370 and 38.3%), respectively. Body fat level, which is the component of overweight that leads to pathology, is a better representative over body mass index. These first percentile curves will be at great assistance helping the medical community to identify obesity in these children at early stages and to prevent development at pathological diseases early in their lives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981172"}
{"pmid": "20981170", "title": "The sural sensory/radial motor amplitude ratio for the diagnosis of peripheral neuropathy in type 2 diabetic patients.", "content": "The sural sensory/radial motor amplitude ratio for the diagnosis of peripheral neuropathy in type 2 diabetic patients. The diagnosis of peripheral diabetic neuropathy is based on clinical examination. Nerve conduction study (NCS) enables earlier diagnosis, but it is demanding and requires specialised personnel. In an attempt to simplify the procedure, this study aimed to identify a new electrophysiological index, which might correlate with results obtained on standardised NCS in patients with long-standing type 2 diabetes. Medical records of type 2 diabetic patients evaluated for neuropathy by NCS were reviewed retrospectively. This analysis included 104 patients (50 men, 54 women) with a mean age of 67.1±5.5 years and mean diabetes duration of 13.1±2.7 years. NCS was performed on radial, ulnar, sural, and peroneal nerves. Neuropathy was defined as impaired NCS. Ratios of neurophysiological parameters from these nerves were calculated and each of them was compared with diagnosis of neuropathy. The sural sensory/radial motor amplitude ratio had the best combination of sensitivity (85%) and specificity (71%) for neuropathy. It also remained the strongest independent predictor of neuropathy in multivariate regression analysis: low levels of this ratio yielded an odds ratio of 7.7 for neuropathy. The sural sensory/radial motor amplitude ratio has a high sensitivity and a moderately high specificity for the diagnosis of neuropathy, low levels being associated with a nearly eightfold increase in the risk for neuropathy. These results encourage further evaluation of this and other electrophysiological indices to enable wider availability of NCS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981170"}
{"pmid": "20981171", "title": "Insomnia symptoms among Greek adolescent students with excessive computer use.", "content": "Insomnia symptoms among Greek adolescent students with excessive computer use. The aim of the present study is to assess the intensity of computer use and insomnia epidemiology among Greek adolescents, to examine any possible age and gender differences and to investigate whether excessive computer use is a risk factor for developing insomnia symptoms. Cross-sectional study of a stratified sample of 2195 high school students. Demographic data were recorded and two specific questionnaires were used, the Adolescent Computer Addiction Test (ACAT) and the Athens Insomnia Scale (AIS). Females scored higher than males on insomnia complaints but lower on computer use and addiction. A dosemediated effect of computer use on insomnia complaints was recorded. Computer use had a larger effect size than sex on insomnia complaints. Duration of computer use was longer for those adolescents classified as suffering from insomnia compared to those who were not. Computer use can be a significant cause of insomnia complaints in an adolescent population regardless of whether the individual is classified as addicted or not.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981171"}
{"pmid": "20981173", "title": "Weaver syndrome associated with bilateral congenital hip and unilateral subtalar dislocation.", "content": "Weaver syndrome associated with bilateral congenital hip and unilateral subtalar dislocation. Weaver syndrome is a congenital paediatric syndrome characterized by mental, respiratory and musculoskeletal manifestations. The coexisting deformities of the skull, the face, fingers and toes are typical. We report a case of a girl with Weaver syndrome associated with rare bilateral congenital dislocation of the hips associated with congenital hypoplastic talus and subtalar dislocation of her ankle joint. A 3-year old girl was admitted in our department with typical manifestations of Weaver syndrome, associated with congenital dislocation of bilateral hips, hypoplastic talus and subtalar dislocation of her right ankle. She was in pain while standing upright and incapable of independent walking. Both hips were treated operatively with open reduction and bilateral iliac osteotomy. Two years afterwards she had an open reduction of her talus and extraarticular arthrodesis of her subtalar joint in her right ankle. Six years postoperatively after the hip operations and four years after the ankle operation the girl is ambulant with a painless independent and unaided walking with a mild limp and full range of movements in all the operated joints. We suggest that children with Weaver syndrome and disabling musculosceletal deformities, particularly affecting their ability to stand up and walk should be treated early, before bone maturity, in order to achieve the best potential musculoskeletal as well as developmental outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981173"}
{"pmid": "20981174", "title": "Effective treatment of antiphospholipid syndrome with plasmapheresis and rituximab.", "content": "Effective treatment of antiphospholipid syndrome with plasmapheresis and rituximab. With the exception of the catastrophic antiphospholipid syndrome (APS), the management of patients with APS has been largely supportive aiming at avoiding a recurrent thrombotic event; it is noteworthy that data concerning therapy targeting the triggering factor (the antiphopsholipid antibodies) are scarce. We report a case of APS manifested as recurrent fetal losses, ischemic stroke and renal dysfunction with concomitant nephrotic syndrome successfully treated with the combination of plasmapheresis and anti-CD20 antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981174"}
{"pmid": "20981176", "title": "Electrocardiographic findings compatible with Brugada syndrome in a patient with febrile respiratory infection.", "content": "Electrocardiographic findings compatible with Brugada syndrome in a patient with febrile respiratory infection. Brugada syndrome is an inherited autosomal dominant-type disease characterized by ST-segment abnormalities and increased fatal ventricular tachyarrhythmias. We hereby present a 57-years-old patient with no symptoms or history of cardiovascular disease, diagnosed with febrile respiratory infection (39℃). Electrocardiographic (ECG) findings were typical of Brugada-like type I syndrome that gradually turned to Brugada type II and III, following fever remission, and finally became normal. Other clinical evaluation tests (echocardiographic evaluation, treadmill stress test, Holter ECG, procainamide provocation test) did not relate to Brugada syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981176"}
{"pmid": "20981177", "title": "KAATSU: Rationale for application in Astronauts.", "content": "KAATSU: Rationale for application in Astronauts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981177"}
{"pmid": "20981175", "title": "Unicystic ameloblastoma of the maxillary sinus: Pitfalls of diagnosis and management.", "content": "Unicystic ameloblastoma of the maxillary sinus: Pitfalls of diagnosis and management. Ameloblastoma is a common odontogenic tumor of the jaws that comprises 3 variants: conventional (solid), unicystic and peripheral ameloblastomas. Unicystic ameloblastoma (UA) in the maxillary sinus is very rare. With a secondary infection, the clinical features may lead to incorrect diagnosis and treatment. A 19-year-old man was referred for the management of sinusitis and a mass at the right cheek. A few weeks earlier, the patient presented with acute cellulitis at the same area and underwent an incision and drainage in a primary care unit without any appropriate investigation. A radiographic examination revealed a massive lesion in the right maxillary sinus. An unerupted tooth within the lesion was found at the level of the orbital floor. The patient was successfully treated by enucleation of the tumor and curettage. The specimen was sent for histopathological examination, and the definite diagnosis was UA. The patient has been followed-up periodically for 5 years without recurrence. This case report suggests that primary care doctors should pay attention to differential diagnosis of orofacial lesions. It is therefore of great benefit to organize continuing education for general physicians who initially meet oral disease patients as a 'gate keeper'. Errors of clinical diagnosis and management of orofacial lesions would be minimized. Pitfalls of diagnosis and management of UA in the maxillary sinus were briefly reviewed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981175"}
{"pmid": "20981178", "title": "Tobacco consummation: Is it still a dilemma?", "content": "Tobacco consummation: Is it still a dilemma?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981178"}
{"pmid": "20981179", "title": "Venous thromboembolism prophylaxis for hospitalized medical patients, current status and strategies to improve.", "content": "Venous thromboembolism prophylaxis for hospitalized medical patients, current status and strategies to improve. Venous thromboembolism (VTE), comprising life-threatening pulmonary embolism (PE) and its precursor deep-vein thrombosis (DVT), is commonly encountered problem. Although most patients survive DVT, they often develop serious and costly long-term complications. Both unfractionated heparin and low molecular weight heparins significantly reduce the incidence of VTE and its associated complications. Despite the evidence demonstrating significant benefit of VTE prophylaxis in acutely ill medical patients, several registries have shown significant underutilization. This underutilization indicates the need for educational and audit programs in order to increase the number of medical patients receiving appropriate prophylaxis. Many health advocacy groups and policy makers are paying more attention to VTE prophylaxis; the National Quality Forum and the Joint Commission recently endorsed strict VTE risk assessment evaluation for each patient upon admission and regularly thereafter. In the article, all major studies addressing this issue in medical patients have been reviewed from the PubMed. The current status of VTE prophylaxis in hospitalized medical patients is addressed and some improvement strategies are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981179"}
{"pmid": "20981180", "title": "Imaging lung manifestations of HIV/AIDS.", "content": "Imaging lung manifestations of HIV/AIDS. Advances in our understanding of human immunodeficiency virus (HIV) infection have led to improved care and incremental increases in survival. However, the pulmonary manifestations of HIV/acquired immunodeficiency syndrome (AIDS) remain a major cause of morbidity and mortality. Respiratory complaints are not infrequent in patients who are HIV positive. The great majority of lung complications of HIV/AIDS are of infectious etiology but neoplasm, interstitial pneumonias, Kaposi sarcoma and lymphomas add significantly to patient morbidity and mortality. Imaging plays a vital role in the diagnosis and management of lung of complications associated with HIV. Accurate diagnosis is based on an understanding of the pathogenesis of the processes involved and their imaging findings. Imaging also plays an important role in selection of the most appropriate site for tissue sampling, staging of disease and follow-ups. We present images of lung manifestations of HIV/AIDS, describing the salient features and the differential diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981180"}
{"pmid": "20981181", "title": "Asthma insights and reality in the United Arab Emirates.", "content": "Asthma insights and reality in the United Arab Emirates. The burden of asthma in the United Arab Emirates (UAE) and the extent to which guidelines are being followed for optimum asthma control are largely unknown. This survey assessed the current level of asthma control, the burden of the disease, and adherence to asthma guidelines by patients. A face-to-face interview of 200 asthmatics in the UAE was conducted. In addition to the questionnaire administered by expert interviewers, each respondent self-completed an Asthma Control Test. The sample was stratified by region within the country and sampled proportionately. Sudden severe attacks of asthma were reported by 64% in the past year. Day time symptoms and night time symptoms were reported by 57.5% and 35.5%, respectively, in the past 4 weeks. Overall, 52.8% of the children and 17.1% of the adults missed school and work in the past year, respectively. The percentage of asthmatics that had emergency room visits within the past year was 27.5%, and 4% were hospitalized. Only 5.5% used inhaled corticosteroids in the past year and 47.5% were on short-acting beta-2 agonists. Only 17.8% ever owned a peak flow meter and only 30% ever had a lung function test. Only 17% had scheduled follow-up and 66% were followed-up by general practitioners. This survey shows that the current level of asthma control in the UAE is far from optimal. Therefore, it is necessary to increase the awareness among patients and update doctors about asthma control guidelines for attaining optimal asthma control, and thus reducing the burden of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981181"}
{"pmid": "20981182", "title": "Assessment of visual evoked potentials in stable COPD patients with no visual impairment.", "content": "Assessment of visual evoked potentials in stable COPD patients with no visual impairment. To assess whether patients having stable chronic obstructive pulmonary disease (COPD) with no clinical evidence of visual impairment or peripheral neuropathy have visual evoked potentials (VEP) abnormalities on electrophysiologic evaluation. In the present study, 80 male subjects with no clinical neuropathy or visual impairment were included; 40 COPD patients and 40 age-matched healthy volunteers. The characteristics of subjects including age, quantum of smoking, duration of illness (in COPD patients only), and spirometric indices {forced expiratory volume in first second (FEV₁), FEV₁/forced vital capacity (FVC) %, and peak expiratory flow rate (PEFR)} were assessed. The mental status was assessed using a questionnaire Mini-Mental State Examination (MMSE) Questionnaire. Electrophysiologic studies for the evaluation of VEP were carried out on computerized equipment. Latency and amplitude of P100 wave were analyzed from the VEP wave patterns obtained through a standardized protocol in both the groups to detect abnormalities in the COPD group. For the COPD group, correlations of P100 parameters with patient characteristics, spirometric indices, and MMSE scores were assessed. Significant abnormality was defined as a variation beyond healthy volunteer mean ± 3 standard deviation. We observed significantly prolonged latency and decreased amplitude of P100 in both eyes of the patients in COPD group compared with healthy volunteers. Twenty-two of the 40 COPD patients (55%) had significant abnormalities in P100 latency, and three COPD patients (7.5%) had abnormalities in P100 amplitude. The latency of P100 on the right side had statistically significant inverse correlation with FEV₁/FVC% and MMSE score. Twenty-three of the 40 stable COPD patients (compared with healthy volunteers) were observed to have significant VEP abnormality detected on electrophysiologic evaluation: 21/40 having prolonged P100 latency and only 2/40 with decreased P100 amplitude. The statistically significant correlations were observed only between P100 latency (right eye) and FEV1/FVC as well as MMSE scores. The rest of the correlations were not statistically significant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981182"}
{"pmid": "20981183", "title": "Prophylactic use of laxative for constipation in critically ill patients.", "content": "Prophylactic use of laxative for constipation in critically ill patients. This study was designed to evaluate the use of laxative prophylaxis for constipation in intensive care unit (ICU) and the impact of early versus late bowel movement on patient's outcome. The study was a prospective, randomized controlled trial in critically ill ventilated adult patients, who were expected to stay on ventilator for >72 h. Control group did not receive any intervention for bowel movement for the first 72 h, whereas interventional group received prophylactic dose of lactulose 20 cc enterally every 12 h for the first 72 h. The parameters measured during the study were admission diagnosis, age, gender, comorbid conditions, admission Simplified Acute Physiologic Score (SAPS II), sedative and narcotic agents with doses and duration, timing and tolerance of nutrition, daily assessment of bowel movement, total use of prokinetic, doses of suppositories, and enema for first bowel movement, total number of days on ventilator, weaning failures, extubation or tracheostomy, ICU length of stay, and death or discharge. A total of 100 patients were enrolled, 50 patients in each control and interventional group. Mean age was 38.8 years, and both groups had male predominance. Mean SAPS II score for both was 35. Mean dose of Fentanyl (323.8 ± 108.89 mcg/h in control and 345.83 ± 94.43 mcg/h in interventional group) and mean dose of Midazolam (11.1 ± 4.04 mg/h in control and 12.4 ± 3.19 mg/h in interventional group). There were only two (4%) patients in control, while nine (18%) patients in interventional group who had bowel movement in <72 h (P < 0.05). Mean ventilator days were 16.19, and 17.36 days in control and interventional groups, respectively. Subgroup analysis showed that the patients who moved bowel in <5 days in both groups had mean ventilator days of 18.5, whereas it was 15.88 days for the patients who moved bowel after 5 days in both groups (P< 0.05). Mean ICU days for control was 21.15 ± 10.44 and 20.77 ± 8.33 days for interventional group. Forty-eight (96%) patients in each group were discharged from the ICU. Two (4%) patients died in ICU in each group. Laxative prophylaxis can be used successfully to prevent constipation in ICU patients. Late bowel movement >5 days is associated with less ventilator days, compared to early <5 days bowel movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981183"}
{"pmid": "20981184", "title": "Evaluation of a novel method to assess corticosteroid responsiveness in chronic obstructive pulmonary disease.", "content": "Evaluation of a novel method to assess corticosteroid responsiveness in chronic obstructive pulmonary disease. Some patients with chronic obstructive pulmonary disease (COPD) may benefit from oral steroid therapy. These steroid-responsive patients are diagnosed based on laboratory spirometry. We hypothesize that daily, home-based spirometry is a better tool. Thirty patients with COPD underwent a single-blinded study, with a crossover design. They received 2 weeks of placebo followed by 2 weeks of prednisone therapy (40 mg/day). Laboratory spirometry was done at the beginning and end of the study and daily home-based spirometry was done twice a day. Analysis of variance model was used. The variability of the median day-to-day forced expiratory volume in 1 s (FEV₁) was 72.5 mL (25th percentile of 40 mL and 75th percentile of 130 mL). The daily FEV₁ variation was 70 mL (25th percentile of 50 mL and 75th percentile of 100 mL). The overall laboratory FEV₁ variability was larger after the steroid course (P < 0.001), but not clinically significant. The variability was not significant postplacebo treatment compared with the baseline values. For home-based spirometry, steroid treatment was not significantly different. The majority (97%) completed more than 80% of the measurements. Ninety percent of the performed tests were considered acceptable. Only 53% of the tests were considered accurate. Overall both laboratory and home-based measurements did not show significant association between airway responsiveness and dyspnea or exercise capacity. Twice-daily home measurements of FEV₁ might be better than the conventional approach to identify steroid responsive COPD patients. However, this finding was only statistically but not clinically significant. Therefore, we would not recommend this approach to identify COPD patients with steroid responsiveness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981184"}
{"pmid": "20981185", "title": "A case-control study of bidi smoking and bronchogenic carcinoma.", "content": "A case-control study of bidi smoking and bronchogenic carcinoma. To evaluate the risks imposed by tobacco smoking, in particular, bidi smoking, in the development of lung cancer. Two hundred eighty-four histologically confirmed patients of bronchogenic carcinoma and 852 controls matched for age, sex, and socioeconomic status were interviewed according to a predesigned questionnaire. Effects of individual variables defining the various aspects of tobacco smoking, in particular, bidi smoking, were assessed using logistic regression models. 81.3% cases of bronchogenic carcinoma were ever smokers as compared with 42.2% among controls. The odd ratios for ever smoking, bidi smoking, and cigarette smoking were 5.9 (confidence interval [CI] 4.3, 8.4), 6.1 (CI 4.3, 8.7), and 5.3 (CI 2.7, 10.4), respectively. Bidi smoking poses a very high risk for lung cancer even more than that of cigarette smoking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981185"}
{"pmid": "20981186", "title": "Endobronchial cryobiopsy or forceps biopsy for lung cancer diagnosis.", "content": "Endobronchial cryobiopsy or forceps biopsy for lung cancer diagnosis. Invasive procedures such as bronchoscopic biopsy, bronchial washing, and bronchial brushing are widely used in diagnosis of lung cancers. The mean diagnostic rate with bronchoscopic forceps biopsy is 74% in central tumors. This study was designed to evaluate the efficacy of cryobiopsies in histopathological diagnosis. Forty-one patients who had interventional bronchoscopy were included in this study. Three forceps biopsies and one cryobiopsy with cryorecanalization probe were obtained from each subject. Biopsies interpretations were done by one expert pathologist. Hemorrhage was the only complication in both procedures. There was no significant difference between these two procedures in the incidence of hemorrhage (P > 0.05). Mean diameters of samples taken with forceps biopsy and cryoprobe biopsy were 0.2 and 0.8 cm, respectively (P < 0.001). Thirty-two patients (78%) were diagnosed with forceps biopsies, and 38 patients (92.7%) were diagnosed with cryoprobe biopsies (P = 0.031). We concluded that cryoprobe biopsies were more successful than forceps biopsies in diagnosis. Nevertheless, further investigations are warranted to determine an efficacy of cryoprobe biopsy procedures and a rationale to use as a part of routine flexible bronchoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981186"}
{"pmid": "20981187", "title": "Nonresolving pleural effusion in an elderly woman: A case report.", "content": "Nonresolving pleural effusion in an elderly woman: A case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981187"}
{"pmid": "20981189", "title": "H1N1 infection and thyroid storm.", "content": "H1N1 infection and thyroid storm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981189"}
{"pmid": "20981190", "title": "Tobacco smoking by medical students: KAP study.", "content": "Tobacco smoking by medical students: KAP study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981190"}
{"pmid": "20981193", "title": "Influenza vaccination program for medical workers.", "content": "Influenza vaccination program for medical workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981193"}
{"pmid": "20981195", "title": "Large orthotopic reservoir stone burden: Role of open surgery.", "content": "Large orthotopic reservoir stone burden: Role of open surgery. To present our experience in open poucholithotomy as a primary management of large orthotopic reservoir stone burden and discuss different management options. Records of men underwent radical cystectomy and orthotopic urinary diversion were retrospectively reviewed as regards pouch stone formation. Patients with large reservoir stone burden managed by open poucholithotomy were further selected. Large reservoir stone burden was encountered in 12 post radical cystectomy men. All underwent open poucholithotomy as a primary management of their reservoir stones. Median age at cystectomy was 46 (range: 32-55) years with a median total follow up period of 214.15 (range: 147-257) months and a median interval to stone detection of 99 (range: 63-132) months. The median stone burden was 5260 (range: 3179-20410) mm(2). All patients were continent during the day while 5 showed nocturnal enuresis; 2 of them became continent after removal of the stones. Post poucholithotomy, all patients had sterile urine cultures except one who showed occasional colonization. None of the 12 patients showed stone recurrence after poucholithotomy. Two patients underwent revision of a dessuscepted nipple valve in association with stone removal. Open poucholithotomy for large reservoir stone burden is a feasible and safe option. It saves the reservoir mesentery and adjacent bowel. It allows complete removal of the stone(s) leaving no residual fragments. Furthermore, it permits correction of concomitant reservoir abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981195"}
{"pmid": "20981194", "title": "Assessment of angiogenic factor, vascular endothelial growth factor, serum and urine level changes in superficial bladder tumor immunotherapy by intravesical Bacillus Calmette-Guerin.", "content": "Assessment of angiogenic factor, vascular endothelial growth factor, serum and urine level changes in superficial bladder tumor immunotherapy by intravesical Bacillus Calmette-Guerin. Bladder tumor is one of the most common genitourinary tumors. Management of non-muscle invasive (NMI) bladder tumors is primarily by transurethral resection (TURBT) followed by intravesical immunotherapy or chemotherapy. Bacillus Calmette-Guerin (BCG) is the most effective adjuvant therapy in NMI bladder tumor. Since angiogenesis is an essential factor in solid tumor progression and vascular endothelial growth factor (VEGF) is an important factor in angiogenesis, the aim of this study is the assessment of angiogenic factor, VEGF, serum and urine level changes in superficial bladder tumor immunotherapy by intravesical BCG. A total of 23 patients with bladder transitional cell carcinoma (TCC) in stage Ta/T1 or carcinoma insitu (CIS), low or high grade, which passed a 2-4 week period from TURBT participated in this study. Blood and urine samples were obtained at first and sixth sessions before instillation of BCG. Enzyme-linked immunosorbent assay (ELISA) method was used to obtain VEGF level in samples. Urine and serum VEGF levels did not change significantly before and after BCG therapy. Changes in VEGF level were significantly different neither in low grade against high grade tumors nor in stage T1 against stage Ta tumors. A significant difference in VEGF level was seen between low grade and high grade tumors in serum after BCG therapy (P=0.007); but not in urine samples. Although intravesical BCG possesses anti-angiogenic activity, it seems that it exerts its effect through pathways other than VEGF, especially in low grade tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981194"}
{"pmid": "20981196", "title": "Diagnostic significance of atypical category in the voided urine samples: A retrospective study in a tertiary care center.", "content": "Diagnostic significance of atypical category in the voided urine samples: A retrospective study in a tertiary care center. Voided urine samples continue to play an important role in the surveillance of urothelial malignancy and also as a screening mode for high risk patients. In some cases, it is difficult to reliably distinguish changes induced by inflammation, stone or other reactive condition from neoplasm, and these cases are categorized as atypical. The aim of our study is to evaluate the prevalence and the significance of atypical diagnosis in the voided urine samples and also to identify the cytomorphologic features that are seen more frequently in the atypical malignant urine samples. All voided urine cytology samples with a diagnosis of atypical urothelial cells, between the period of 2000 and 2009, were obtained from the cytology database. Only those cases with histologic follow-up were included in the study. The cytology and the histology slides were retrieved and reviewed. The following parameters were evaluated: cellularity, cell clusters, nuclear membrane irregularities, hyperchromasia and India-ink type nuclei, the presence of spindle cells and the cytoplasmic characteristics. Out of 72 voided urine samples included in the study, 49 cases (68%) had a positive histologic diagnosis of urothelial malignancy in the follow-up histology; of these (55%) were high-grade urothelial carcinoma. Increased cellularity, papillary cell clusters, nuclear membrane irregularity, hyperchromasia and India-ink type nuclei were observed more frequently in the atypical malignant urine samples, while cytoplasmic vacuolization were seen more in the negative reactive urine samples. The atypical category diagnosis is associated with a significant proportion of urothelial carcinoma. It should be used by the pathologist to convey concern to the clinician in difficult cases that may require close follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981196"}
{"pmid": "20981197", "title": "Continuous ambulatory peritoneal dialysis catheter placement: Is omentectomy necessary?", "content": "Continuous ambulatory peritoneal dialysis catheter placement: Is omentectomy necessary? There are different methods of continuous ambulatory peritoneal dialysis (CAPD) catheter placement. Open surgical technique is a widely followed method. The complication rate following catheter placement varies and catheter blockage due to omental plugging is one of the main reasons. To analyze the need for routine omentectomy during CAPD catheter placement. This was a retrospective analysis of 58 CAPD catheter placements performed between July 2002 and June 2007. Tenckhoff double cuffed catheter was used in all. The postoperative complications were analyzed. There were 44 males and 14 females. The mean age was 51 years ranging from 15 to 76 years. Of these, 40 (69%) patients underwent omentectomy (group A) and 18 (31%) did not (group B). Laparoscopic and open techniques were performed in 5 and 53 patients, respectively. Omentectomy was not performed in 13 patients with open technique and all the five in the laparoscopic group. One patient in group A developed hemoperitoneum which was treated conservatively. None from group A developed catheter blockage, whereas five (27.8%) from group B developed catheter blockage postoperatively. The median time interval between the primary procedure and development of catheter blockage was 45 days (ranged from 14 to 150 days). Omentectomy during CAPD catheter placement prevents catheter blockage and secondary interventions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981197"}
{"pmid": "20981198", "title": "Urological manifestations of Chikungunya fever: A single centre experience.", "content": "Urological manifestations of Chikungunya fever: A single centre experience. Chikungunya is a viral infection often associated with lower urinary tract dysfunction. This study evaluates the urological squeal of Chikungunya fever in a single centre after an epidemic in 2006-2007 in India. Retrospective analysis of medical records of 13 patients with lower urinary tract symptoms after Chikungunya fever was evaluated and outcome following intervention assessed. A total of 13 patients (M:F=9:4), with age ranging from 30 to 72 years, were included in the study. They presented with chronic urinary retention (n=9, 69.23%) of which two had paraparesis, voiding symptoms alone (n=7, 53.8%), storage symptoms alone (n=3, 23%), and acute urinary retention (n=1, 7.6%). Presentation with lower urinary tract symptoms after an episode of Chikungunya fever was after a mean period of 163 days (range 30-360 days). Mean serum creatinine on presentation was 1.8 mg/dl (0.6-6.5 mg/dl). Evaluation revealed dilated upper tract in four (30.7%) patients. Cystometrography showed acontractile detrusor (n=3, 37.5%), hypocontractile detrusor (n=3, 37.5%), overactive detrusor (n=1, 12.5%) and normal study (n=1, 12.5%). At the mean follow up of 11 months, 11 patients (84.6%) had satisfactory functional outcome after intervention, namely supra pubic diversion and bladder training (n=5, 38.4%), alpha blocker (n=3, 23%), timed frequent voiding (n=2, 15.3%), clean intermittent catheterization (n=2, 15.3%), trial void with alpha blocker (n=1, 7.6%) while two are on continuing supra pubic diversion due to persistent neurological deficit. Chikungunya fever is an uncommon entity in urological practice, often associated with urinary symptoms. An accurate assessment of the symptoms and timely intervention prevents upper tract deterioration and improves the quality of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981198"}
{"pmid": "20981199", "title": "Endoscopic placement of double-J ureteric stents in children as a treatment for primary obstructive megaureter.", "content": "Endoscopic placement of double-J ureteric stents in children as a treatment for primary obstructive megaureter. To determine the efficacy and potential complications of double-J ureteric stents in the treatment of persistent or progressive primary obstructive megaureter in pediatric patients within our institution. A retrospective case-note review of all patients with double-J ureteric stents, between 1997 and 2004, was performed. In all, 38 stents were inserted in 31 patients aged between 2 months and 15 years of age. Complications and results of follow-up investigations and the need for follow-up investigations were recorded. Patients were followed up clinically and radiologically for a minimum of 2 years following stent insertion. Endoscopic placement of double-J ureteric stents in childhood is straightforward and complications are uncommon (8/38 insertions). In non-resolving or progressive primary non-refluxing megaureter, double-J ureteric stenting alone is effective with resolution of primary non-refluxing megaureter in 66% of cases (25/38 insertions). Ureteric stenting provides an alternative to early surgery in patients with primary non-refluxing megaureter. The youngest patient in our series was 2 months old at the time of endoscopic ureteric double-J stent insertion. Endoscopic placement of ureteric double-J stents should be considered as a first-line treatment in the management of persistent or progressive non-refluxing megaureter leading to progressive hydronephrosis or pyonephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981199"}
{"pmid": "20981200", "title": "Subcapsular renal hematoma after ureterorenoscopy: An unknown complication of a known procedure.", "content": "Subcapsular renal hematoma after ureterorenoscopy: An unknown complication of a known procedure. Renal subcapsular hematoma is not an uncommon complication after extracorporeal short wave lithotripsy, trauma, renal angiographic procedures and spontaneously in patients of malignancy and in patients on anticoagulation. We present a patient who developed renal subcapsular hematoma after ureterorenoscopy, which has not been mentioned in literature ever. Clinical spectrum varies from spontaneous resolution through acute renal failure to Page kidney. Page kidney is the external compression of a kidney usually caused by a subcapsular hematoma associated with high blood pressure and occasional renal failure. It is named after Dr. Irvin Page who first demonstrated in 1939 that wrapping cellophane tightly around animal kidneys could cause hypertension. Various management options are mentioned in literature and depend upon the severity of hematoma. Percutaneous drainage is a successful option for the management of subcapsular hematoma in hemodynamic stable patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981200"}
{"pmid": "20981201", "title": "Primary renal adenosquamous carcinoma.", "content": "Primary renal adenosquamous carcinoma. A case of renal adenosquamous carcinoma is presented. The fact that the urothelium has no glandular or squamous structures makes the pathogenesis of this tumor unique. The process is assumed to begin with urothelial metaplasia resulting from chronic irritation leading to dysplasia and subsequently squamous and glandular differentiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981201"}
{"pmid": "20981202", "title": "Xanthogranulomatous cystitis: A rare clinical entity.", "content": "Xanthogranulomatous cystitis: A rare clinical entity. Xanthogranulomatous cystitis (XC) is a rare benign disease of unknown etiology. A case of XC in a 30-year-old male is presented due to sparcity of such case report in medical literature. Patient evaluation included clinical, biochemical and radiological studies before treatment. Histological study revealed the rare diagnosis. Patient was asymptomatic at eight weeks follow-up after treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981202"}
{"pmid": "20981203", "title": "Upper gastro-intestinal bleeding - Rare presentation of renal cell carcinoma.", "content": "Upper gastro-intestinal bleeding - Rare presentation of renal cell carcinoma. Renal cell carcinoma (RCC) constitutes 2-3% of all adult malignancies and often diagnosed incidentally. Classical tried of RCC now rarely seen, it behaves unpredictably and having diverge range of clinical manifestation including paraneoplastic syndromes. Upper gastrointestinal (GI) bleeding due to stomach metastasis of RCC is uncommon and to the best of our knowledge, only few cases are reported in world literature and most of them were diagnosed during follow-up after complete treatment of RCC but in our case, it was the primary manifestation of disease. Our case also demonstrates the importance of imaging in undiagnosed cases of upper GI bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981203"}
{"pmid": "20981204", "title": "Giant adrenal myelolipoma: Incidentaloma with a rare incidental association.", "content": "Giant adrenal myelolipoma: Incidentaloma with a rare incidental association. Adrenal myelolipoma is an unusual, benign and biochemically inactive tumor that is composed of mature adipose and hematopoietic tissue. It is usually diagnosed accidentally and nowadays much more frequently because of widespread use of ultrasonography, computed tomography (CT) and magnetic resonance imaging. Adrenal myelolipoma is usually unilateral and asymptomatic, though known to be associated with obesity, hypertension, endocrinological disorders and some malignancies. We report herein two cases of right-sided giant adrenal myelolipoma diagnosed by multidetector-row CT. One patient was symptomatic because of a large mass in the right upper abdomen, which on imaging with CT was seen to be right adrenal myelolipoma. Another patient had a large left side Bochdalek hernia and right adrenal myelolipoma was incidentally discovered on CT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981204"}
{"pmid": "20981206", "title": "The role of serum pepsinogen in the detection of gastric cancer.", "content": "The role of serum pepsinogen in the detection of gastric cancer. The incidence of gastric cancer is very high in Japan, Korea, and China. Reducing the morbidity and mortality associated with gastric cancer requires early diagnosis, which can be facilitated by applying gastroscopy more frequently in high-risk groups. A strategy of population screening for gastric cancer is currently being adopted in Korea, Japan, and the Matsu region of Taiwan, but using different screening methods. In addition, the history of pepsinogen (PG) in research as a gastric cancer biomarker has varied, in that the use of serum levels of PGI and PGII and the PGI/PGII ratio as gastric cancer screening tools was introduced in Japan before 1990, but in Korea the first research results were only reported in 2008. This review first evaluates the physiology of PG, followed by the usefulness or limitations of serum PG testing with regard to the detection of gastric cancer. Finally, the factors affecting the efficacy of PG tests as a gastric cancer biomarker (i.e., Helicobacter pylori infection status, gender, histopathologic features, and cancer location and depth) are evaluated. It was found that the strategies used to increase the efficacy of PG tests should be individualized in each country according to the seroprevalence of H. pylori.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981206"}
{"pmid": "20981207", "title": "Halimeter ppb Levels as the Predictor of Erosive Gastroesophageal Reflux Disease.", "content": "Halimeter ppb Levels as the Predictor of Erosive Gastroesophageal Reflux Disease. In a previous issue published in Gut and Liver, we found that erosive changes in the esophagogastroduodenal mucosa were strongly correlated with increased levels of volatile sulfur-containing compounds (VSC), suggesting that halitosis could be a symptom reflecting the erosive status of the upper gut mucosa. Together with other studies showing a possible association between halitosis and gastroesophageal reflux disease (GERD), under the premise that halitosis could be one of extraesophageal manifestations of erosive GERD (ERD), we investigated the significance of Halimeter ppb levels on ERD compared to non-erosive gastroesophageal reflux disease (NERD). Subjects were assigned to the NERD group if there was no evidence of esophageal erosive changes on endoscopy, despite reflux symptoms, and to the ERD group if they had GERD A, B, C, or D (according to the Los Angeles classification). The VSC levels were measured in all patients with either a Halimeter (before endoscopy) or by gas chromatography of the gastric juices aspirated during endoscopy. The VSC level differed significantly between the NERD and ERD groups (p<0.0001), suggesting that this can be used to discriminate between NERD and ERD. However, the VSC level did not differ significantly with the severity of GERD. Even though hiatal hernia and a body mass index of >24 kg/m(2) was significantly associated with ERD, there was no correlation with Halimeter ppb levels. Minimal-change lesions exhibited the highest VSC levels, signifying that minimal change lesions can be classified as ERD based on our finding that halimeter ppb levels were descrimitive of erosive change. Erosive changes in the esophageal mucosa were strongly associated with VSC levels, supporting the hypothesis that halitosis can be a potential biomarker for the discrimination between ERD and NERD, reflecting the presence of erosive change in the lower esophagogastric junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981207"}
{"pmid": "20981208", "title": "Is colonoscopy necessary in children suspected of having colonic polyps?", "content": "Is colonoscopy necessary in children suspected of having colonic polyps? The clinical spectrum, histology, and endoscopic features of colonic polyps in the pediatric age group were studied to evaluate the role of colonoscopy in children suspected of having colonic polyps. Seventy-six patients with colorectal polyps were studied. Investigations included barium enema (n=6), sigmoidoscopy (n=17), and colonoscopy (n=53) at the initial visit. Colonoscopy was also performed in 23 patients who received barium enema or sigmoidoscopy. Data related to age, gender, family history, signs, symptoms, size, location, polyp types, and associated diseases were collected and analyzed. Among the 76 patients, juvenile polyps were detected in 58 (76.3%), potentially premalignant polyposis in 17 (22.4%), familial adenomatous polyposis in 11 (14.5%), Peutz-Jegher syndrome in 4 (5.3%), and juvenile polyposis syndrome in 2 (2.6%). Twenty-two patients (28.9%) had polyps in the upper colon. All patients with potentially malignant polyps had polyps in both the upper colon and rectosigmoid colon. Although most of the children with colorectal polyps had juvenile polyps, a significant number of cases showed multiple premalignant and proximally located polyps. This finding emphasizes the need for a colonoscopy in such patients. Thus, the risk of malignant change, particularly in children with multiple polyps, makes surveillance colonoscopy necessary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981208"}
{"pmid": "20981205", "title": "The role of bacteria in the pathogenesis of inflammatory bowel disease.", "content": "The role of bacteria in the pathogenesis of inflammatory bowel disease. Crohn's disease (CD) and ulcerative colitis (UC) have features that suggest bacterial involvement, and all genetic models of inflammatory bowel disease (IBD) require the presence of commensal bacteria. CD is associated with innate immune response genes such as NOD2/CARD15 and the autophagy genes ATG16L1 and IRGM. However, IBD responds to immunosuppression, suggesting that any bacteria involved are not acting as conventional pathogens. Molecular techniques are rapidly advancing our knowledge of the gut microbiota. In CD there is reduced diversity, and notably a reduction in the probiotic Faecalibacterium prausnitzii, the presence of which in the terminal ileum is associated with a reduced risk of recurrence following surgery. There is also a consistent increase in mucosa-associated Escherichia coli with an \"adherent and invasive\" phenotype, which allows them to replicate inside macrophages and induce granulomas. Speculation that CD could be caused by the Mycobacterium avium subspecies paratuberculosis (MAP) continues. The response to antitumor necrosis factor treatments suggests that, if relevant at all, MAP is not acting as a conventional pathogen. However, there is increased colonization by MAP in CD, and there is evidence that it could have an indirect effect mediated by the suppression of macrophage function. UC relapse is frequently associated with infection by pathogens, but there is less evidence for involvement of a specific bacterial species. Poor barrier integrity followed by an inflammatory reaction to bacterial components, with chronicity maintained by an autoimmune process, seems a plausible pathogenic model. Bacterial theories of pathogenesis are now becoming testable by targeted therapeutic interventions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981205"}
{"pmid": "20981209", "title": "Risk Factors for Treatment Failure and Recurrence after Metronidazole Treatment for Clostridium difficile-associated Diarrhea.", "content": "Risk Factors for Treatment Failure and Recurrence after Metronidazole Treatment for Clostridium difficile-associated Diarrhea. The incidence of treatment failure or recurrence of Clostridium difficile-associated diarrhea (CDAD) following metronidazole treatment has increased recently. We studied the treatment failure, recurrence rate, and risk factors predictive of treatment failure and recurrence after metronidazole treatment for CDAD. We retrospectively identified consecutive patients who were admitted and treated for CDAD at a single tertiary institution in Korea over a recent 10-year period (i.e., 1998-2008). Metronidazole was administered as the initial treatment to 111 of 117 patients (94.9%) with CDAD. Fourteen patients (12.6%) had no clinical response to the metronidazole treatment, and in 13 patients (13.4%) CDAD recurred after successful metronidazole treatment. Diabetes mellitus (p=0.014) and sepsis (p=0.002) were independent risk factors for metronidazole treatment failure. Patients who had received surgery within 1 month before CDAD developed were more likely to experience a recurrence after metronidazole treatment (p=0.032). Vancomycin exhibited a higher response rate after treatment failure, and metronidazole showed a reasonable response rate in the treatment of recurrence. Treatment failure and recurrence rates increased with time after metronidazole treatment for CDAD over the 10-year study period. Our data suggest that diabetes mellitus and sepsis are independent risk factors for metronidazole treatment failure, and that operation history within 1 month of development of CDAD is a predictor of a recurrence after metronidazole treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981209"}
{"pmid": "20981210", "title": "Sacroiliitis is common in Crohn's disease patients with perianal or upper gastrointestinal involvement.", "content": "Sacroiliitis is common in Crohn's disease patients with perianal or upper gastrointestinal involvement. Sacroiliitis (SI) is one of the most frequent extraintestinal manifestations in inflammatory bowel disease (IBD) patients, but the exact prevalence has not been evaluated in Asia. There are few data on the association between SI and other clinical features of IBD. The prevalence of SI was evaluated using computed tomography (CT) and the phenotypic parameters associated with SI in Korean IBD patients were determined. Eighty-two patients with ulcerative colitis (UC) and 81 patients with Crohn's disease (CD) were evaluated clinically. The presence of SI was evaluated using bone window setting of abdomino-pelvic CT images by two radiologists. The prevalence rates of SI were 12.2% and 21.0% in the UC and CD groups, respectively. There was no relationship between the localization or extent of intestinal inflammation and the presence of SI in the UC group. Multivariate analyses confirmed that perianal and upper-gastrointestinal (from the mouth through to the jejunum) diseases were associated with the occurrence of SI in the CD group (p=0.026 and p=0.047, respectively). SI was as common among Korean IBD patients as among Western patients. Perianal or upper-gastrointestinal involvement is associated with SI in CD patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981210"}
{"pmid": "20981211", "title": "Associations between the Plasticity Region Genes of Helicobacter pylori and Gastroduodenal Diseases in a High-Prevalence Area.", "content": "Associations between the Plasticity Region Genes of Helicobacter pylori and Gastroduodenal Diseases in a High-Prevalence Area. Genes associated with the Helicobacter pylori (H. pylori) plasticity region may play a role in the pathogenesis of H. pylori. We compared the genes jhp0940, jhp0947, and jhp0986 in H. pylori isolates from patients with different gastroduodenal diseases and in different age groups. The H. pylori hyperplasticity region genes jhp0940, jhp0947, and jhp0986 were studied by PCR. We also evaluated whether these genes were related to the cytotoxin-associated gene (cagA) and histology findings. Of the patient cohort, 71 (62%) were positive for jhp0940, 67 (59%) for jhp0947, 12 (10%) for jhp0986, and 69 (60%) for cagA. jhp0940 (n=18, 67%) and jhp0947 (n=23, 85%) were found more frequently in duodenal ulcer (DU) patients than in gastritis patients (n=14, 39%; p=0.029 and p<0.001, respectively). Gastric ulcer (GU) was more frequently associated with jhp0940 (17 patients, 77%; p=0.003) than with gastritis (14 patients, 39%). Gastric carcinoma (GC) was more strongly associated with both jhp0940 (22 patients, 76%; p=0.003) and jhp0947 (22 patients, 76%; p=0.003) than was gastritis (14 patients, 39%). jhp0947 was more frequently associated with chronic active inflammation (58 patients, 87%; p=0.009) than with chronic inflammation (9 patients, 13%). Multivariate analysis demonstrated that jhp0947 was associated with DU (odds ratio, 6.1; 95% confidence interval, 1.87-20). The genes jhp0947 and jhp0940 were identified in H. pylori isolates from patients with GC and DU, while jhp0940 was also isolated from patients with GU. jhp0947 was independently associated with DU.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981211"}
{"pmid": "20981212", "title": "Secondary appendiceal tumors: a review of 139 cases.", "content": "Secondary appendiceal tumors: a review of 139 cases. This study evaluated the clinicopathologic characteristics of patients with secondary appendiceal tumors (SATs). We performed a single-center, retrospective study of patients with pathologically confirmed SATs. Among 180 cases of appendiceal malignancies diagnosed between 2000 and 2007, 139 cases (77.2%, 46 male) were SATs. The median age at SAT diagnosis was 55 years. The most common primary origin was the ovary. The mode of appendiceal involvement was metastasis in 122 and invasion in 17 patients. Extra-appendiceal involvement was present in 134 patients. The only manifestation that could be attributed to the SAT itself was appendicitis (n=8). Serosal involvement was predominant. The median survival after diagnosis of SAT was 22.6 months. In the Cox regression analysis, chemotherapy included in the treatment was the only factor associated with prolonged survival (hazards ratio, 0.12; 95% confidence interval, 0.06-0.23; p<0.001). Complete resection of the SAT had no influence on survival. SATs accounted for 77.2% of all pathologically diagnosed appendiceal malignancies. The most common origin was the ovary. SATs were usually associated with widespread disease, and the median survival after SAT diagnosis was 22.6 months. Complete resection of the SAT had no influence on survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981212"}
{"pmid": "20981213", "title": "Efficacy of rifaximin compared with ciprofloxacin for the treatment of acute infectious diarrhea: a randomized controlled multicenter study.", "content": "Efficacy of rifaximin compared with ciprofloxacin for the treatment of acute infectious diarrhea: a randomized controlled multicenter study. Ciprofloxacin has been widely prescribed for acute infectious diarrhea. However, the resistance to this drug is increasing. Rifaximin is a novel but poorly absorbed rifamycin derivative. This study evaluated and compared the efficacies of rifaximin and ciprofloxacin for the treatment of acute infectious diarrhea. We performed a randomized controlled multicenter study in Korea. Patients with acute diarrhea were enrolled and randomized to receive rifaximin or ciprofloxacin for 3 days. The primary efficacy endpoint was the time to last unformed stool (TLUS). Secondary endpoints were enteric wellness (reduction of at least 50% in the number of unformed stools during 24-hour postenrollment intervals), general wellness (subjective feeling of improvement), and proportion of patients with treatment failure. Intent-to-treat analysis (n=143) showed no significant difference between the rifaximin and ciprofloxacin groups in the mean TLUS (36.1 hours vs 43.6 hours, p=0.163), enteric wellness (49% vs 57%, p=0.428), general wellness (67% vs 78%, p=0.189), or treatment failure rate (9% vs 12%, p=0.841). The adverse events did not differ significantly between the two groups. These results suggest that rifaximin is as safe and effective as ciprofloxacin in the treatment of acute infectious diarrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981213"}
{"pmid": "20981214", "title": "What are the risk factors for acute suppurative cholangitis caused by common bile duct stones?", "content": "What are the risk factors for acute suppurative cholangitis caused by common bile duct stones? Acute suppurative cholangitis (ASC), a severe form of acute cholangitis, is a life-threatening condition that must be treated with appropriate and timely management. The purpose of this study was to identify the factors that predispose patients to ASC. We retrospectively investigated 181 patients (100 men, 81 women; age, 70.66±7.38 years, mean±SD) who were admitted to Wonkwang University Hospital between January 2005 and June 2007 for acute cholangitis with common bile duct (CBD) stones. All patients underwent endoscopic retrograde cholangiopancreatogram to remove the stones. Variables and factors that could be assessed upon admission were analyzed to identify the risk factors for the development of ASC. Of the 181 patients, 44 (24.3%) presented with ASC. On multivariate analysis, the followings were found to be independent risk factors for the development of ASC: impacted common bile duct stone (p=0.010), current smoker status (p=0.008), advanced age (>70 years; p=0.002), and gallstone (p=0.016). The most commonly isolated organisms in bile culture were Enterococcus species, Escherichia coli, and Klebsiella species. Impacted bile-duct stones, current smoking, advanced age, and gallstones were identified as independent risk factors for the development of ASC in patients with CBD stones. These results suggest that emergency biliary drainage is beneficial in patients with these risk factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981214"}
{"pmid": "20981215", "title": "Effect of transdermal fentanyl patches on the motility of the sphincter of oddi.", "content": "Effect of transdermal fentanyl patches on the motility of the sphincter of oddi. Pain is one of the most troublesome symptoms of pancreatitis. Transdermal fentanyl patches (TFPs) are long-acting analgesics with a reduced risk of dependency. This prospective study evaluated the effect of TFPs on sphincter of Oddi (SO) motility for the management of pain in pancreatitis. SO manometry (SOM) was performed using triple-lumen catheters anterogradely inserted through the percutaneous transhepatic route during cholangioscopy in 16 patients. The basal pressure, amplitude, and frequency of the SO were assessed before and after applying a TFP at 24 hour at doses of 25 and 12.5µg/hr, respectively. Two of 16 patients receiving a 25µg/hr. TFP were excluded because of adverse side effects (headache and/or nausea). The mean basal pressure, amplitude, and frequency of SOM did not change significantly in the 25µg/hr TFP group (n=4 patients). Parameters of SO function also did not significantly change in the 12.5µg/hr TFP group (n=11 patients). TFPs below a dose of 25µg/hr may not affect the motility of the SO. Administration of TFPs at lower dosages seems to be a safe analgesic treatment for the pain control of patients with pancreatitis without affecting the function of the SO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981215"}
{"pmid": "20981216", "title": "Efficacy and long-term outcome of endoscopic treatment of sporadic nonampullary duodenal adenoma.", "content": "Efficacy and long-term outcome of endoscopic treatment of sporadic nonampullary duodenal adenoma. Endoscopic resection has proven to be a safe and effective alternative to surgery for duodenal adenomas. However, few data are available on the adequacy of resection and long-term outcomes. This study evaluated the efficacy and longterm endoscopic findings in a cohort of Korean patients who underwent endoscopic mucosal resection (EMR) of sporadic duodenal adenomas. Seventeen patients with nonampullary duodenal adenomas without familial polyposis syndrome and who were treated by EMR between January 2001 and December 2007 were evaluated retrospectively. Their management, follow-up, and outcomes were reviewed. In total, seventeen lesions were removed from EMR in 17 patients (mean age, 59.3 years; 6 women, 11 men). The mean size of the tumors was 15.1 mm (median, 13 mm, range, 8-27 mm). Of these 17 adenomas, 16 adenomas were tubulous and 1 was tubulovillous. The EMR was performed successfully in all 17 patients in a single session. After a median follow-up period of 29 months (range, 13-72 months), all patients remained in remission. One patient had bleeding at the site of the EMR. There were no perforations after the EMR. EMR for sporadic duodenal adenomas seemed to be a safe and effective treatment modality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981216"}
{"pmid": "20981217", "title": "Serum uric Acid as a predictor for the development of nonalcoholic Fatty liver disease in apparently healthy subjects: a 5-year retrospective cohort study.", "content": "Serum uric Acid as a predictor for the development of nonalcoholic Fatty liver disease in apparently healthy subjects: a 5-year retrospective cohort study. This study evaluated the relationship between hyperuricemia and nonalcoholic fatty liver disease (NAFLD) by comparing the incidence rates of NAFLD in relation to serum uric acid levels in apparently healthy subjects during a 5-year period. Among 15,638 healthy Korean subjects who participated in a health-screening program in 2003 and 2008, respectively, 4954 subjects without other risk factors were enrolled in this study. We compared the incidence rates of NAFLD in 2008 with respect to baseline uric acid levels. In 2003, serum uric acid levels were categorized into the following quartiles: 0.6-3.9, 3.9-4.8, 4.8-5.9, and 5.9-12.6 mg/dL. The incidence of NAFLD in 2008 increased with the level of baseline uric acid (5.6%, 9.8%, 16.2%, and 20.9%, respectively; p<0.05). Multiple logistic regression analysis demonstrated that hyperuricemia was associated with the development of NAFLD. When compared to the subjects in quartile 1, the odds ratio (OR) for the incidence of NAFLD for quartiles 2, 3, and 4 were 1.53 (95% confidence interval [CI], 1.09-2.16; p=0.014], 1.69 (95% CI, 1.17-2.44; p=0.005), and 1.84 (95% CI, 1.25-2.71; p=0.002), respectively. High serum uric acid levels appear to be associated with an increased risk of the development of NAFLD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981217"}
{"pmid": "20981218", "title": "Transcatheter arterial chemoembolization for hepatic recurrence after curative resection of pancreatic adenocarcinoma.", "content": "Transcatheter arterial chemoembolization for hepatic recurrence after curative resection of pancreatic adenocarcinoma. Despite curative resection, hepatic recurrences cause a significant reduction in survival in patients with primary pancreatic adenocarcinoma. Transcatheter arterial chemoembolization (TACE) has recently been used successfully to treat primary and secondary hepatic malignancy. Between 2003 and 2008, 15 patients underwent TACE because of hepatic recurrence after curative resection of a pancreatic adenocarcinoma. The tumor response was evaluated based on computed tomography scans after TACE. The overall duration of patient survival was measured. After TACE, a radiographically evident response occurred in six patients whose tumors demonstrated a tumor blush on angiography. Four patients demonstrated stabilization of a hypovascular mass. The remaining five patients demonstrated continued progression of hypovascular hepatic lesions. The median survival periods from the time of diagnosis and from the time of initial TACE were 9.6 and 7.5 months, respectively. TACE may represent a viable therapeutic modality in patients with hepatic recurrence after curative resection of pancreatic adenocarcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981218"}
{"pmid": "20981220", "title": "A case of solitary rectal diverticulum presenting with a retrorectal mass.", "content": "A case of solitary rectal diverticulum presenting with a retrorectal mass. Colonic diverticula are common whereas but rectal diverticula are very rare, with only sporadic reports in the literature since 1911. Most patients with rectal diverticula are diagnosed incidentally, inflammatory processes may have developed at the time of the diagnosis. We report the case of a 42-year-old woman presenting with a retrorectal mass that was detected incidentally. She was suspected of having a rectal diverticulum by transrectal ultrasonography and magnetic resonance imaging. However, the colonoscopic findings were unremarkable. A rectal diverticulum was confirmed intraoperatively, and a transanal diverticulectomy was performed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981220"}
{"pmid": "20981219", "title": "Fanconi's Syndrome Associated with Prolonged Adefovir Dipivoxil Therapy in a Hepatitis B Virus Patient.", "content": "Fanconi's Syndrome Associated with Prolonged Adefovir Dipivoxil Therapy in a Hepatitis B Virus Patient. Adefovir dipivoxil (ADV) is commonly used as an antiviral agent in the treatment of chronic hepatitis B or human immunodeficiency virus infection. Nephrotoxicity has been shown to occur at daily dosages of 60-120 mg. Fanconi's syndrome is a generalized dysfunction of the renal proximal tubular cells, which is usually accompanied by complications. Here we report a case of Fanconi's syndrome in a chronic hepatitis B patient who had been treated with a prolonged regimen of ADV at 10 mg/day. A 47-year-old man complained of severe back and chest-wall pain. He had chronic hepatitis B and had been treated with ADV at a daily dose of 10 mg for 38 months. He was hospitalized because of severe bone pain, and laboratory and radiologic findings suggested a diagnosis of Fanconi's syndrome with osteomalacia. After discontinuation of the ADV, he recovered and was discharged from hospital. His laboratory findings had normalized within 2 weeks. This case indicates that Fanconi's syndrome can be acquired by a chronic hepatitis B patient taking ADV at a conventional dosage of 10 mg/day. Therefore, patients treated with long-term ADV should be checked regularly for the occurrence of ADV-induced Fanconi's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981219"}
{"pmid": "20981221", "title": "Peroral direct cholangioscopic-guided biopsy and photodynamic therapy using an ultraslim upper endoscope for recurrent hepatocellular carcinoma with intraductal tiny nodular tumor growth.", "content": "Peroral direct cholangioscopic-guided biopsy and photodynamic therapy using an ultraslim upper endoscope for recurrent hepatocellular carcinoma with intraductal tiny nodular tumor growth. Bile-duct invasion is rare in patients with hepatocellular carcinoma (HCC). We report a case that received peroral direct cholangioscopy (PDCS)-guided endoscopic biopsy and photodynamic treatment (PDT) for recurrent HCC with intraductal tiny nodular tumor growth. A 64-year-old woman presented with recurrent right upper-quadrant pain. Six months previously she had been diagnosed with HCC with bile-duct invasion in the right anterior segment and had received right anterior segmentectomy. On pathological examination, the margin of resection was clear, but macroscopic bile-duct invasion was noted. On admission, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography (ERCP) revealed a 0.5-cm-sized polypoid mass at the hilar portion. ERCP-guided biopsy failed, and an ampullary stricture was noted. PDCS-guided endoscopic biopsy was thus performed, and histopathology of the retrieved specimen revealed HCC. The patient submitted to PDT. There was no procedure-related complication. After 1 month of PDT the polypoid lesion and scar change at the hilar lesion had disappeared.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981221"}
{"pmid": "20981222", "title": "Signet ring cell carcinoma of the extrahepatic bile duct.", "content": "Signet ring cell carcinoma of the extrahepatic bile duct. Most tumors affecting the extrahepatic bile duct are adenocarcinomas; the other histologic types occur only rarely. We herein report the extremely rare case of signet ring cell carcinoma (SRCC) originating from the extrahepatic bile duct. A 55-year-old man was hospitalized for jaundice and pruritus. Computed tomography and positron emission tomography suggested the presence of distal extrahepatic bile-duct cancer. He underwent a pylorus preserving pancreaticoduodenectomy. A histologic study confirmed a signet ring cell neoplasm of the distal common bile duct. Because the upper resection margin was invaded by the tumor, he received postoperative concurrent chemoradiotherapy and four cycles of chemotherapy. The patient has survived with no evidence of recurrence for 2 years. This is the second case of primary SRCC of the distal extrahepatic bile duct reported in the literature; further reports of cases are warranted to determine the nature of SRCC in the extrahepatic bile duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981222"}
{"pmid": "20981223", "title": "Tufting Enteropathy with EpCAM Mutations in Two Siblings.", "content": "Tufting Enteropathy with EpCAM Mutations in Two Siblings. Tufting enteropathy is a rare autosomal recessive disorder presenting with early-onset severe intractable diarrhea. The epithelial cell adhesion molecule gene (EpCAM) has recently been identified as the gene responsible for tufting enteropathy. Based on histology, a diagnosis of tufting enteropathy was made in two Korean siblings. They developed chronic diarrhea and failure to thrive. They had a broad nasal bridge and micrognathia. Duodenal and colonic biopsies showed villous atrophy, disorganization of surface enterocytes, and focal crowding resembling tufts. Protracted diarrhea continued and so cyclic parenteral nutrition was supplied. The sister had juvenile rheumatoid arthritis. Mutation analysis of EpCAM identified two compound heterozygous mutations in these siblings: 1) a donor splicing site mutation in intron 5 (c.491+1G>A) and 2) a novel nonsense mutation in exon 3 (c.316A>T, Lys106X). Analysis of EpCAM will be useful for genetic counseling and prenatal diagnosis of tufting enteropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981223"}
{"pmid": "20981224", "title": "Colonoscopic clipping as a treatment for appendiceal bleeding.", "content": "Colonoscopic clipping as a treatment for appendiceal bleeding. Bleeding from the appendix has been reported very rarely in patients with lower-gastrointestinal-tract bleeding. In general, after a colonoscopic diagnosis of appendiceal bleeding, laparoscopic or surgical appendectomy would be recommended. Two patients with continuous bleeding from the appendix were treated with partial occlusion of the appendiceal orifice by colonoscopic clipping. In neither case was there evidence of further active bleeding over the following 12 months. This is the first report of such a treatment in the English literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981224"}
{"pmid": "20981225", "title": "A case of phlegmonous gastritis associated with marked gastric distension.", "content": "A case of phlegmonous gastritis associated with marked gastric distension. Phlegmonous gastritis is an acute and severe infectious disease that is occasionally fatal if the diagnosis is delayed. Alcohol consumption, an immunocompromised state (e.g., due to HIV infection, rheumatoid arthritis, diabetes mellitus, or adult T-cell lymphoma), and mucosal injury of the stomach are reported to be predisposing factors. The main treatments for phlegmonous gastritis are antibiotics administration or surgery. In this case, the patient's stomach was markedly distended due to long-lasting gastric-outlet obstruction, which is thought to be the predisposing factor for phlegmonous gastritis. We inserted a metal stent at the obstructed site palliatively due to strong refusal by the patient for surgery. The patient recovered after stenting and antibiotic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981225"}
{"pmid": "20981226", "title": "An inflammatory myofibroblastic tumor of the ampulla of vater successfully managed with endoscopic papillectomy: report of a case.", "content": "An inflammatory myofibroblastic tumor of the ampulla of vater successfully managed with endoscopic papillectomy: report of a case. Inflammatory myofibroblastic tumors (IMTs) are solid neoplastic mesenchymal proliferations composed of myofibroblastic spindle cells admixed with inflammatory infiltrates. The documented sites in the gastrointestinal tract include the esophagus, small intestine, colon, appendix, rectum, pancreas, spleen, liver, and Meckel's diverticulum. Biliary IMTs are rare, and IMTs arising from the ampulla of Vater have not been reported previously. Herein we report the case of a 65-year-old woman with an extrahepatic biliary obstruction due to IMT of the ampulla of Vater, and a successful therapeutic approach using endoscopic ultrasonography and endoscopic papillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981226"}
{"pmid": "20981227", "title": "Treatment of hepatocellular carcinoma with portal vein thrombosis by sorafenib combined with hepatic arterial infusion chemotherapy.", "content": "Treatment of hepatocellular carcinoma with portal vein thrombosis by sorafenib combined with hepatic arterial infusion chemotherapy. Treatment with sorafenib prolongs both the median survival and time to progression by nearly 3 months in patients with advanced hepatocellular carcinoma. Although the effects of combining sorafenib therapy with other anticancer treatment modalities have not been clarified, combination treatment is strongly expected to be beneficial. We report the case of a 50-year-old man who exhibited a partial response and portal vein thrombosis (PVT) revascularization after sorafenib combined with hepatic arterial infusion chemotherapy (HAIC). He exhibited a decrease in tumor size and PVT after 2 months of sorafenib monotherapy. However, no additional response was seen during the subsequent 2 months. To achieve a better tumor response, we combined HAIC with sorafenib. Daily cisplatin (7 mg/m(2) on days 1-5) and 5-fluorouracil (170 mg/m(2) on days 1-5) were infused repeatedly every 4 weeks, and the sorafenib prescription was modified. After four cycles of combined therapy, both the tumor size and PVT were much improved and exhibited partial response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981227"}
{"pmid": "20981229", "title": "Frameshift Mutation of MARS Gene Encoding an Aminoacyl-tRNA Synthetase in Gastric and Colorectal Carcinomas with Microsatellite Instability.", "content": "Frameshift Mutation of MARS Gene Encoding an Aminoacyl-tRNA Synthetase in Gastric and Colorectal Carcinomas with Microsatellite Instability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981229"}
{"pmid": "20981228", "title": "Bile-Duct Stone Removal under Direct Transnasal Cholangioscopy Using an Ultraslim Upper Endoscope.", "content": "Bile-Duct Stone Removal under Direct Transnasal Cholangioscopy Using an Ultraslim Upper Endoscope. The transnasal endoscopic examination using an ultraslim upper endoscope may be more comfortable and less stressful than the peroral approach. Transnasal endoscopic retrograde cholangiopancreatography (ERCP), endoscopic nasobiliary drainage, and direct peroral cholangioscopy using an ultraslim upper endoscope have recently been reported. An 82-year-old woman with a previous history of endoscopic sphincterotomy and stone removal was admitted with acute cholangitis. Instead of conventional ERCP, we performed direct transnasal cholangioscopy (TNC) using an ultraslim upper endoscope for biliary decompression and stone removal because of her unstable vital signs. Direct TNC using an ultraslim upper endoscope may be useful in selected patients with biliary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981228"}
{"pmid": "20981230", "title": "Analysis of nucleotide variations in genes of iron management in patients of Parkinson's disease and other movement disorders.", "content": "Analysis of nucleotide variations in genes of iron management in patients of Parkinson's disease and other movement disorders. The capacity to act as an electron donor and acceptor makes iron an essential cofactor of many vital processes. Its balance in the body has to be tightly regulated since its excess can be harmful by favouring oxidative damage, while its deficiency can impair fundamental activities like erythropoiesis. In the brain, an accumulation of iron or an increase in its availability has been associated with the development and/or progression of different degenerative processes, including Parkinson's disease, while iron paucity seems to be associated with cognitive deficits, motor dysfunction, and restless legs syndrome. In the search of DNA sequence variations affecting the individual predisposition to develop movement disorders, we scanned by DHPLC the exons and intronic boundary regions of ceruloplasmin, iron regulatory protein 2, hemopexin, hepcidin and hemojuvelin genes in cohorts of subjects affected by Parkinson's disease and idiopathic neurodegeneration with brain iron accumulation (NBIA). Both novel and known sequence variations were identified in most of the genes, but none of them seemed to be significantly associated to the movement diseases of interest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981230"}
{"pmid": "20981232", "title": "Gender dependence for a subset of the low-abundance signaling proteome in human platelets.", "content": "Gender dependence for a subset of the low-abundance signaling proteome in human platelets. The incidence of cardiovascular diseases is ten-times higher in males than females, although the biological basis for this gender disparity is not known. However, based on the fact that antiplatelet drugs are the mainstay for prevention and therapy, we hypothesized that the signaling proteomes in platelets from normal male donors might be more activated than platelets from normal female donors. We report here that platelets from male donors express significantly higher levels of signaling cascade proteins than platelets from female donors. In silico connectivity analysis shows that the 24 major hubs in platelets from male donors focus on pathways associated with megakaryocytic expansion and platelet activation. By contrast, the 11 major hubs in platelets from female donors were found to be either negative or neutral for platelet-relevant processes. The difference may suggest a biological mechanism for gender discrimination in cardiovascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981232"}
{"pmid": "20981233", "title": "Developmental pharmacogenetics in pediatric rheumatology: utilizing a new paradigm to effectively treat patients with juvenile idiopathic arthritis with methotrexate.", "content": "Developmental pharmacogenetics in pediatric rheumatology: utilizing a new paradigm to effectively treat patients with juvenile idiopathic arthritis with methotrexate. Although methotrexate is widely used in clinical practice there remains significant lack of understanding of its mechanisms of action and the factors that contribute to the variability in toxicity and response seen clinically. In addition to differences in drug administration, factors that affect pharmacokinetics and pharmacodynamics such as genetic variation may explain individual differences in drug biotransformation. However, the pediatric population has an additional factor to consider, namely the ontogeny of gene expression which may result in variation throughout growth and development. We review the current understanding of methotrexate biotransformation and the concept of ontogeny, with further discussion of how to implement a developmental pharmacogenomics approach in future studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981233"}
{"pmid": "20981231", "title": "Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder.", "content": "Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder. Bipolar disorder (BD) is a chronic and often severe psychiatric illness characterized by manic and depressive episodes. Among the most effective treatments, mood stabilizers represent the keystone in acute mania, depression, and maintenance treatment of BD. However, treatment response is a highly heterogeneous trait, thus emphasizing the need for a structured informational framework of phenotypic and genetic predictors. In this paper, we present the current state of pharmacogenomic research on long-term treatment in BD, specifically focusing on mood stabilizers. While the results provided so far support the key role of genetic factors in modulating the response phenotype, strong evidence for genetic predictors is still lacking. In order to facilitate implementation of pharmacogenomics into clinical settings (i.e., the creation of personalized therapy), further research efforts are needed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981231"}
{"pmid": "20981234", "title": "Pharmacogenetics of anticoagulants.", "content": "Pharmacogenetics of anticoagulants. Warfarin, acenocoumarol, and phenprocoumon are among the major anticoagulant drugs worldwide. Because of their low therapeutic index and serious adverse reactions (ADRs), their wide use, and their varying kinetics and pharmacogenetic dependence, it is of great importance to explore further possibilities to forecast the dose beyond conventional INR measurements. Here, we describe particulars of the relative pharmacogenetic influence on the kinetics of these agents, the population distribution of genetics risk groups, and novel data on clinical features with influence on dose requirement and ADR risk. The usefulness of genetic information prior to and soon after start of therapy is also discussed. The current renewed focus on these issues is caused not only because of new genetic knowledge and genotyping facilities but also because of the high rate of serious ADRs. Application of these measures in the care of patients with anticoagulant therapy is important awaiting new therapeutic principles to be introduced, which may take long time still.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981234"}
{"pmid": "20981236", "title": "Genome-wide linkage and association scans for quantitative trait Loci of serum lactate dehydrogenase-the framingham heart study.", "content": "Genome-wide linkage and association scans for quantitative trait Loci of serum lactate dehydrogenase-the framingham heart study. Serum lactate dehydrogenase (LDH) is used in diagnosing many diseases and is significantly determined by genetic factors. Three genes coding for LDH isoenzymes were mapped to chromosome 11q15 and 12p12. We used 330 Framingham Heart Study largest families for microsatellite linkage scan and 100K SNPs association scan to determine quantitative trait loci of LDH level. We estimated the heritability at 41%. Our genome-wide linkage analysis yielded several chromosomal regions, other than 11q and 12p, with LOD scores between 1 and 2.5. None of the 100K SNPs with a P-value <10(-4) in our genome-wide association study was close to the chromosomal regions where the LDH genes reside. Our study demonstrated a strong genetic effect on the variation of LDH levels. There may not be a single gene with a large effect, instead may be several genes with small effects in controlling the variation of serum LDH. Those genes may be located on chromosomal regions that differ from where the genes encoding LDH isoenzymes reside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981236"}
{"pmid": "20981238", "title": "Thermal mixing of two miscible fluids in a T-shaped microchannel.", "content": "Thermal mixing of two miscible fluids in a T-shaped microchannel. In this paper, thermal mixing characteristics of two miscible fluids in a T-shaped microchannel are investigated theoretically, experimentally, and numerically. Thermal mixing processes in a T-shaped microchannel are divided into two zones, consisting of a T-junction and a mixing channel. An analytical two-dimensional model was first built to describe the heat transfer processes in the mixing channel. In the experiments, de-ionized water was employed as the working fluid. Laser induced fluorescence method was used to measure the fluid temperature field in the microchannel. Different combinations of flow rate ratios were studied to investigate the thermal mixing characteristics in the microchannel. At the T-junction, thermal diffusion is found to be dominant in this area due to the striation in the temperature contours. In the mixing channel, heat transfer processes are found to be controlled by thermal diffusion and convection. Measured temperature profiles at the T-junction and mixing channel are compared with analytical model and numerical simulation, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981238"}
{"pmid": "20981235", "title": "Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology.", "content": "Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology. Glutathione transferase enzymes (GSTs) catalyze reactions in which electrophiles are conjugated to the tripeptide thiol glutathione. While many GST-catalyzed transformations result in the detoxication of xenobiotics, a few substrates, such as dihaloalkanes, undergo bioactivation to reactive intermediates. Many molecular epidemiological studies have tested associations between polymorphisms (especially, deletions) of human GST genes and disease susceptibility or response to therapy. This review presents a discussion of the biochemistry of GSTs, the sources-both genetic and environmental-of interindividual variation in GST activities, and their implications for pharmaco- and toxicogenetics; particular attention is paid to the Theta class GSTs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981235"}
{"pmid": "20981237", "title": "Integrated electrical concentration and lysis of cells in a microfluidic chip.", "content": "Integrated electrical concentration and lysis of cells in a microfluidic chip. Lysing cells is an important step in the analysis of intracellular contents. Concentrating cells is often required in order to acquire adequate cells for lysis. This work presents an integrated concentration and lysis of mammalian cells in a constriction microchannel using dc-biased ac electric fields. By adjusting the dc component, the electrokinetic cell motion can be precisely controlled, leading to an easy switch between concentration and lysis of red blood cells in the channel constriction. These two operations are also used in conjunction to demonstrate a continuous concentration and separation of leukemia cells from red blood cells in the same microchannel. The observed cell behaviors agree reasonably with the simulation results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981237"}
{"pmid": "20981240", "title": "Successful treatment of early endometrial carcinoma by local delivery of levonorgestrel: a case report.", "content": "Successful treatment of early endometrial carcinoma by local delivery of levonorgestrel: a case report. We describe a case of a 67-year-old Caucasian woman with an early, moderately-differentiated adenocarcinoma of the endometrium. A levonorgestrel-releasing intrauterine system was inserted, which she tolerated well. A full D&C, following removal of the device, was performed after 9 months, confirming absence of tumoral tissue. Examination after 24 months showed a very thin endometrium, indicating complete remission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981240"}
{"pmid": "20981239", "title": "Lipid mediators in skin inflammation: updates and current views.", "content": "Lipid mediators in skin inflammation: updates and current views.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981239"}
{"pmid": "20981243", "title": "Mixed deterministic and probabilistic networks.", "content": "Mixed deterministic and probabilistic networks. The paper introduces mixed networks, a new graphical model framework for expressing and reasoning with probabilistic and deterministic information. The motivation to develop mixed networks stems from the desire to fully exploit the deterministic information (constraints) that is often present in graphical models. Several concepts and algorithms specific to belief networks and constraint networks are combined, achieving computational efficiency, semantic coherence and user-interface convenience. We define the semantics and graphical representation of mixed networks, and discuss the two main types of algorithms for processing them: inference-based and search-based. A preliminary experimental evaluation shows the benefits of the new model.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981243"}
{"pmid": "20981241", "title": "Toll-like receptor signaling pathways--therapeutic opportunities.", "content": "Toll-like receptor signaling pathways--therapeutic opportunities. Toll-like receptors (TLRs) are transmembrane proteins acting mainly as sensors of microbial components. Triggering TLRs results in increased expression of multiple inflammatory genes, which then play a protective role against infection. However, aberrant activation of TLR signaling has a significant impact on the onset of cancer, allergy, sepsis and autoimmunity. Various adaptor proteins, including MyD88, IRAKs, TIRAP, TRIF, and TRAM, are involved in specific TLR signaling pathways. This article reviews the role of these molecules in TLR signaling, and discusses the impact of this pathway on various disease scenarios. Given their important role in infectious and non-infectious disease settings, TLRs and their signaling pathways emerge as attractive targets for therapeutics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981241"}
{"pmid": "20981244", "title": "Order-free co-regionalized areal data models with application to multiple-disease mapping.", "content": "Order-free co-regionalized areal data models with application to multiple-disease mapping. With the ready availability of spatial databases and geographical information system software, statisticians are increasingly encountering multivariate modelling settings featuring associations of more than one type: spatial associations between data locations and associations between the variables within the locations. Although flexible modelling of multivariate point-referenced data has recently been addressed by using a linear model of co-regionalization, existing methods for multivariate areal data typically suffer from unnecessary restrictions on the covariance structure or undesirable dependence on the conditioning order of the variables. We propose a class of Bayesian hierarchical models for multivariate areal data that avoids these restrictions, permitting flexible and order-free modelling of correlations both between variables and across areal units. Our framework encompasses a rich class of multivariate conditionally autoregressive models that are computationally feasible via modern Markov chain Monte Carlo methods. We illustrate the strengths of our approach over existing models by using simulation studies and also offer a real data application involving annual lung, larynx and oesophageal cancer death-rates in Minnesota counties between 1990 and 2000.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981244"}
{"pmid": "20981245", "title": "Enumerating the junction trees of a decomposable graph.", "content": "Enumerating the junction trees of a decomposable graph. We derive methods for enumerating the distinct junction tree representations for any given decomposable graph. We discuss the relevance of the method to estimating conditional independence graphs of graphical models and give an algorithm that, given a junction tree, will generate uniformly at random a tree from the set of those that represent the same graph. Programs implementing these methods are included as supplemental material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981245"}
{"pmid": "20981246", "title": "Curvilinear Immersed Boundary Method for Simulating Fluid Structure Interaction with Complex 3D Rigid Bodies.", "content": "Curvilinear Immersed Boundary Method for Simulating Fluid Structure Interaction with Complex 3D Rigid Bodies. The sharp-interface CURVIB approach of Ge and Sotiropoulos [L. Ge, F. Sotiropoulos, A Numerical Method for Solving the 3D Unsteady Incompressible Navier-Stokes Equations in Curvilinear Domains with Complex Immersed Boundaries, Journal of Computational Physics 225 (2007) 1782-1809] is extended to simulate fluid structure interaction (FSI) problems involving complex 3D rigid bodies undergoing large structural displacements. The FSI solver adopts the partitioned FSI solution approach and both loose and strong coupling strategies are implemented. The interfaces between immersed bodies and the fluid are discretized with a Lagrangian grid and tracked with an explicit front-tracking approach. An efficient ray-tracing algorithm is developed to quickly identify the relationship between the background grid and the moving bodies. Numerical experiments are carried out for two FSI problems: vortex induced vibration of elastically mounted cylinders and flow through a bileaflet mechanical heart valve at physiologic conditions. For both cases the computed results are in excellent agreement with benchmark simulations and experimental measurements. The numerical experiments suggest that both the properties of the structure (mass, geometry) and the local flow conditions can play an important role in determining the stability of the FSI algorithm. Under certain conditions unconditionally unstable iteration schemes result even when strong coupling FSI is employed. For such cases, however, combining the strong-coupling iteration with under-relaxation in conjunction with the Aitken's acceleration technique is shown to effectively resolve the stability problems. A theoretical analysis is presented to explain the findings of the numerical experiments. It is shown that the ratio of the added mass to the mass of the structure as well as the sign of the local time rate of change of the force or moment imparted on the structure by the fluid determine the stability and convergence of the FSI algorithm. The stabilizing role of under-relaxation is also clarified and an upper bound of the required for stability under-relaxation coefficient is derived.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981246"}
{"pmid": "20981247", "title": "Use of preputial skin as cutaneous graft after nevus excision.", "content": "Use of preputial skin as cutaneous graft after nevus excision. We report a four-year-old boy with a nevus covering all the plantar side of his second finger on the left foot. He was also affected by congenital phimosis. Surgical excision of the nevus was indicated, but the skin defect would have been too large to be directly closed. The foreskin was taken as a full-thickness skin graft to cover the cutaneous defect of the finger. The graft intake was favourable and provided a functional repair with good aesthetic characteristic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981247"}
{"pmid": "20981249", "title": "A Summary of the Endocrine Society Clinical Practice Guidelines on Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency.", "content": "A Summary of the Endocrine Society Clinical Practice Guidelines on Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency. Steroid 21-hydroxylase deficiency accounts for about 95% of cases of congenital adrenal hyperplasia (CAH). Newborns are currently being screened for the classical forms of this disease throughout the United States and in 12 other countries. As such, it seems important to develop the best practice guidelines for treating not only infants and children, but affected adults as well. This report gives a brief overview of the most recent expert opinion and clinical practice guidelines for CAH as formulated by The Endocrine Society Task Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981249"}
{"pmid": "20981250", "title": "Biosorption of Lanthanides from Aqueous Solutions Using Pretreated Buccinum tenuissimum Shell Biomass.", "content": "Biosorption of Lanthanides from Aqueous Solutions Using Pretreated Buccinum tenuissimum Shell Biomass. Biosorption experiment from aqueous solutions containing known amount of rare earth elements (REEs) using pre-treated Buccinum tenuissimum shell was explored to evaluate the efficiency of shell biomass as sorbent for REEs. In this work, four kinds of sieved shell samples: (a) \"Ground original sample\", (b) \"Heat-treatment (480°C, 6 hours) sample\", (c) \"Heat-treatment (950°C, 6 hours) sample\" and (d) \"Heat-treatment (950°C, 6 hours) and water added sample\" were used. Furthermore, to confirm the characteristics of the shell biomass, the crystal structure, the surface morphology, and the specific surface area of these shell samples were determined. Consequently, the following matters have been mainly clarified. (1) The crystal structure of the shell biomass was transformed from aragonite (CaCO(3)) into calcite (CaCO(3)) phase by heat-treatment (480°C, 6 hours); then mainly transformed into calcium oxide (CaO) by heat-treatment (950°C, 6 hours), and calcium hydroxide (Ca(OH)(2)) by heat-treatment (950°C, 6 hours) and adding water. (2) The shell biomass showed excellent sorption capacity for lanthanides. (3) Adsorption isotherms using the shell biomass can be described by Langmuir and Freundlich isotherms satisfactorily for lanthanides except \"heat-treatment (950°C, 6 hours) sample\". (4) Shell biomass (usually treated as waste material) can be an efficient sorbent for lanthanides in future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981250"}
{"pmid": "20981251", "title": "Struggling with a Gastric Volvulus Secondary to a Type IV Hiatal Hernia.", "content": "Struggling with a Gastric Volvulus Secondary to a Type IV Hiatal Hernia. Type IV hiatal hernias are characterized by herniation of the stomach along with associated viscera such as the spleen, colon, small bowel, and pancreas through the esophageal hiatus. They are relatively rare, representing only about 5%-7% of all hernias, and can be associated with severe complications. We report a 71-year-old veteran wrestler who presented to our department with a type IV paraesophageal hernia containing a gastric volvulus and treated successfully with emergency operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981251"}
{"pmid": "20981248", "title": "The SSX family of cancer-testis antigens as target proteins for tumor therapy.", "content": "The SSX family of cancer-testis antigens as target proteins for tumor therapy. Cancer-testis antigens (CTAs) represent an expanding class of tumor-associated proteins defined on the basis of their tissue-restricted expression to testis or ovary germline cells and frequent ectopic expression in tumor tissue. The expression of CTA in MHC class I-deficient germline cells makes these proteins particularly attractive as immunotherapeutic targets because they serve as essentially tumor-specific antigens for MHC class I-restricted CD8+ T cells. Moreover, because CTAs are expressed in many types of cancer, any therapeutic developed to target these antigens might have efficacy for multiple cancer types. Of particular interest among CTAs is the synovial sarcoma X chromosome breakpoint (SSX) family of proteins, which includes ten highly homologous family members. Expression of SSX proteins in tumor tissues has been associated with advanced stages of disease and worse patient prognosis. Additionally, both humoral and cell-mediated immune responses to SSX proteins have been demonstrated in patients with tumors of varying histological origin, which indicates that natural immune responses can be spontaneously generated to these antigens in cancer patients. The current review will describe the history and identification of this family of proteins, as well as what is known of their function, expression in normal and malignant tissues, and immunogenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981248"}
{"pmid": "20981252", "title": "A metabonomic comparison of urinary changes in Zucker and GK rats.", "content": "A metabonomic comparison of urinary changes in Zucker and GK rats. To further investigate pathogenesis and pathogenic process of type 2 diabetes mellitus (T2DM), we compared the urinary metabolic profiling of Zucker obese and Goto-kakizaki (GK) rats by NMR-based metabonomics. Principal component analysis (PCA) on urine samples of both models rats indicates markedly elevated levels of creatine/creatinine, dimethylamine, and acetoacetate, with concomitantly declined levels of citrate, 2-ketoglurarate, lactate, hippurate, and succinate compared with control rats, respectively. Simultaneously, compared with Zucker obese rats, the GK rats show decreased levels of trimethylamine, acetate, and choline, as well as increased levels of creatine/creatinine, acetoacetate, alanine, citrate, 2-ketoglutarate, succinate, lactate, and hippurate. This study demonstrates metabolic similarities between the two stages of T2DM, including reduced tricarboxylic acid (TCA) cycle and increased ketone bodies production. In addition, compared with Zucker obese rats, the GK rats have enhanced concentration of energy metabolites, which indicates energy metabolic changes produced in hyperglycemia stage more than in insulin resistance stage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981252"}
{"pmid": "20981254", "title": "A hypothesis test for equality of bayesian network models.", "content": "A hypothesis test for equality of bayesian network models. Bayesian network models are commonly used to model gene expression data. Some applications require a comparison of the network structure of a set of genes between varying phenotypes. In principle, separately fit models can be directly compared, but it is difficult to assign statistical significance to any observed differences. There would therefore be an advantage to the development of a rigorous hypothesis test for homogeneity of network structure. In this paper, a generalized likelihood ratio test based on Bayesian network models is developed, with significance level estimated using permutation replications. In order to be computationally feasible, a number of algorithms are introduced. First, a method for approximating multivariate distributions due to Chow and Liu (1968) is adapted, permitting the polynomial-time calculation of a maximum likelihood Bayesian network with maximum indegree of one. Second, sequential testing principles are applied to the permutation test, allowing significant reduction of computation time while preserving reported error rates used in multiple testing. The method is applied to gene-set analysis, using two sets of experimental data, and some advantage to a pathway modelling approach to this problem is reported.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981254"}
{"pmid": "20981253", "title": "Does valproic acid induce neuroendocrine differentiation in prostate cancer?", "content": "Does valproic acid induce neuroendocrine differentiation in prostate cancer? Valproic Acid (VPA) is a histone deacetylase inhibitor that holds promise for cancer therapy. Here, we investigate whether VPA treatment induces neuroendocrine differentiation of Prostate Cancer (PCa). A tissue microarray of VPA-treated and untreated tumor xenografts and cell lines of human PCa (LNCaP, C4-2, DU145, and PC-3) were generated and were analyzed by immunohistochemical analysis (IHC) for NE markers chromogranin A (CgA), synaptophysin, and NCAM (neural cell adhesion molecule). Western blot analysis for CgA was performed to confirm the results of the TMA. IHC analysis did not reveal any induction of CgA, synaptophysin, or NCAM in any xenograft after VPA treatment in vivo. In vitro, VPA treatment induced little synaptophysin expression in C4-2 and PC-3 cells and NCAM expression in LNCaP and PC-3 cells. In the case of CgA, VPA treatment decreased its expression in vitro in a dose-dependent manner, as determined by western blot analysis. Thus our data demonstrates that VPA does not induce NE differentiation of PCa cells in the physiologically relevant in vivo setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981253"}
{"pmid": "20981257", "title": "The add-on effect of solifenacin for patients with remaining overactive bladder after treatment with tamsulosin for lower urinary tract symptoms suggestive of benign prostatic obstruction.", "content": "The add-on effect of solifenacin for patients with remaining overactive bladder after treatment with tamsulosin for lower urinary tract symptoms suggestive of benign prostatic obstruction. To investigate the add-on effect of solifenacin for Japanese men with remaining overactive bladder (OAB) symptoms after tamsulosin monotherapy for lower urinary tract symptoms (LUTS) suggestive of benign prostatic obstruction (BPO) in real-life clinical practice. Patients aged ≥ 50 having remaining OAB symptoms (≥ 3 of OAB symptom score (OABSS) with ≥2 of urgency score) after at least 4 weeks treatment by 0.2 mg of tamsulosin for BPO/LUTS received 2.5 or 5.0 mg of solifenacin for 12 weeks. The International Prostate Symptom Score (IPSS), QOL index and OABSS, maximum flow rate (Qmax) and postvoid residual urine volume (PVR) were determined. A total of 48 patients (mean age 72.5 years) completed the study. There were significant improvement in IPSS (15.1 to 11.2) and QOL index (4.2 to 3.0) by add-on of solifenacin. Although the IPSS storage symptom score was significantly improved, there were no changes observed in the IPSS voiding symptom score. The OABSS showed significant improvement (8.0 to 4.8). No changes were observed in Qmax and PVR. Under the supervision of an experienced urologist, the additional administration of solifenacin to patients with BPO/LUTS treated with tamsulosin, is effective in controlling remaining OAB symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981257"}
{"pmid": "20981255", "title": "Influence of Hsp90 and HDAC inhibition and tubulin acetylation on perinuclear protein aggregation in human retinal pigment epithelial cells.", "content": "Influence of Hsp90 and HDAC inhibition and tubulin acetylation on perinuclear protein aggregation in human retinal pigment epithelial cells. Retinal pigment epithelial (RPE) cells are continually exposed to oxidative stress that contributes to protein misfolding, aggregation and functional abnormalities during aging. The protein aggregates formed at the cell periphery are delivered along the microtubulus network by dynein-dependent retrograde trafficking to a juxtanuclear location. We demonstrate that Hsp90 inhibition by geldanamycin can effectively suppress proteasome inhibitor, MG-132-induced protein aggregation in a way that is independent of HDAC inhibition or the tubulin acetylation levels in ARPE-19 cells. However, the tubulin acetylation and polymerization state affects the localization of the proteasome-inhibitor-induced aggregation. These findings open new perspectives for understanding the pathogenesis of protein aggregation in retinal cells and can be useful for the development of therapeutic treatments to prevent retinal cell deterioration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981255"}
{"pmid": "20981258", "title": "Direct vasocontractile activities of bupivacaine enantiomers on the isolated rat thoracic aorta.", "content": "Direct vasocontractile activities of bupivacaine enantiomers on the isolated rat thoracic aorta. Background. In vitro studies with isolated arteries have shown direct vasoactivity of racemic bupivacaine. However, there is little information on the direct vasoactivities of bupivacaine enantiomers, S(-)- and R(+)-bupivacaine. Methods. We performed functional examinations using isolated intact thoracic aortic rings from male Wistar rats. Changes in ring tension produced by S(-)-, R(+)-, or racemic bupivacaine were measured in Krebs solution. Results. S(-)-bupivacaine produced the strongest contraction of the three agents. R(+)-bupivacaine showed limited vasoconstriction. The effects of racemic bupivacaine were located between these two. Conclusion. Each bupivacaine enantiomer showed specific vasocontractile activity, which affects the activity of racemic bupivacaine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981258"}
{"pmid": "20981256", "title": "Studies of complex biological systems with applications to molecular medicine: the need to integrate transcriptomic and proteomic approaches.", "content": "Studies of complex biological systems with applications to molecular medicine: the need to integrate transcriptomic and proteomic approaches. Omics approaches to the study of complex biological systems with potential applications to molecular medicine are attracting great interest in clinical as well as in basic biological research. Genomics, transcriptomics and proteomics are characterized by the lack of an a priori definition of scope, and this gives sufficient leeway for investigators (a) to discern all at once a globally altered pattern of gene/protein expression and (b) to examine the complex interactions that regulate entire biological processes. Two popular platforms in \"omics\" are DNA microarrays, which measure messenger RNA transcript levels, and proteomic analyses, which identify and quantify proteins. Because of their intrinsic strengths and weaknesses, no single approach can fully unravel the complexities of fundamental biological events. However, an appropriate combination of different tools could lead to integrative analyses that would furnish new insights not accessible through one-dimensional datasets. In this review, we will outline some of the challenges associated with integrative analyses relating to the changes in metabolic pathways that occur in complex pathophysiological conditions (viz. ageing and altered thyroid state) in relevant metabolically active tissues. In addition, we discuss several new applications of proteomic analysis to the investigation of mitochondrial activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981256"}
{"pmid": "20981260", "title": "Successful endoscopic management of fish bone embedded into the bladder wall.", "content": "Successful endoscopic management of fish bone embedded into the bladder wall. We report a case of a pyogenous vesical abscess resulting from an ingested fish bone embedded in the bladder wall that was treated endoscopically in an asymptomatic man. Computed tomography of the abdomen showed a linear radiopaque structure in the thickened left anterolateral wall of the bladder. Cystoscopy revealed a protruding mass, covered with normal-appearing mucosa, with outflow of pus from a shallow recess. Histopathological findings indicated that the transurethrally removed linear structure, located in the submucosa, was compatible with fish bone. A high index of suspicion should be maintained for the correct diagnosis to be made.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981260"}
{"pmid": "20981259", "title": "Does gender impact intensity of care provided to older medical intensive care unit patients?", "content": "Does gender impact intensity of care provided to older medical intensive care unit patients? Introduction. Women receive less aggressive critical care than men based on prior studies. No documented studies evaluate whether men and women are treated equally in the medical intensive care unit (MICU). The Therapeutic Intervention Scoring System-28 (TISS-28) has been used to examine gender differences in mixed ICU studies. However, it has not been used to evaluate equivalence of care in older MICU patients. We hypothesize that given nonsignificant, baseline health differences between genders at MICU admission, the level of care provided would be equivalent. Methods. Prospective cohort of 309 patients ≥60 years old in the MICU of an urban university teaching hospital. Explanatory variables were demographic data and baseline measures. Primary outcomes were TISS-28 scores and MICU interventions. We compare TISS-28 scores by gender using a statistical test of equivalence. Results. Women were older and had more chronic respiratory failure at MICU admission. Using equivalence limits of ±15% on gender-based scores of TISS-28, MICU interventions were equivalent. Supplementary analysis showed no statistically significant association between gender and mortality. Conclusions. In contrast with other reports from the cardiac critical care literature, as measured by the TISS-28, gender-based care delivered to older MICU patients in this cohort was equivalent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981259"}
{"pmid": "20981261", "title": "Changing trends of breast cancer survival in sultanate of oman.", "content": "Changing trends of breast cancer survival in sultanate of oman. Breast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 years (SD±12.88), with one-third of patients younger than 40 years. The majority of patients presented with stage III (41.2%) and IV (18.2%) breast cancer. T size (P = .023), skin involvement (P = .003), and stage at presentation (P = .004) were significantly associated with overall survival. Skin involvement at presentation (P = .003), T size (P = .09), lymph node status (P = .013), and stage (P = .003) were strong predictors of relapse-free survival. Patients had a 5-year survival of 78%, compared to 64% of breast cancer patients diagnosed between 1996 and 2002 identified in our previously published study. Thus, despite Omani breast cancer patients continuing to present with advanced breast cancer, survival rates have significantly improved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981261"}
{"pmid": "20981262", "title": "Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice.", "content": "Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice. The 3xTg-AD mouse develops a progressive Alzheimer's disease- (AD-) like brain pathology that causes cognitive- and neuropsychiatric-like symptoms of dementia. Since its neuroimmunoendocrine axis is likewise impaired, this mouse is also useful for modelling complex age-related neurodegeneration. This study analyzed behavioral, physiological, neurochemical, pathological and immunoendocrine alterations in male and female 3xTg-AD mice and assayed the effects of a short therapy of forced physical exercise at the moderate pathology stage of 6 months of age. Gender effects were observed in most AD-related pathology and dysfunctions. Five weeks of treadmill training produced beneficial effects, such as the reduction of brain oxidative stress and GABA-A receptor dysfunction in males and improvement of sensorimotor function in females. In both sexes, exercise decreased the brain amyloid β 42/40 ratio levels. The results highlight the importance of analyzing experimental therapies in both mouse model genders in order to improve our understanding of the disease and develop more appropriate therapies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981262"}
{"pmid": "20981263", "title": "Analysis of the pathogenesis of experimental autoimmune optic neuritis.", "content": "Analysis of the pathogenesis of experimental autoimmune optic neuritis. Optic neuritis associated with multiple sclerosis has a strong association with organ-specific autoimmune disease. The goal of our research is to establish an optimal organ-specific animal model to elucidate the pathogenetic mechanisms of the disease and to develop therapeutic strategies using the model. This paper is divided into five sections: (1) clinical picture of optic neuritis associated with multiple sclerosis, (2) elucidation of pathogenesis using animal models with inflammation in optic nerve and spinal cord, (3) clinical relevance of concurrent encephalomyelitis in optic neuritis model, (4) retinal damage in a concurrent multiple sclerosis and optic neuritis model, and (5) development of novel therapies using mouse optic neuritis model. Advanced therapies using biologicals have succeeded to control intractable optic neuritis in animal models. This may ultimately lead to prevention of vision loss within a short period from acute onset of optic neuritis in human. By conducting research flexibly, ready to switch from the bench to the bedside and from the bedside to the bench as the opportunity arises, this strategy may help to guide the research of optic neuritis in the right direction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981263"}
{"pmid": "20981264", "title": "Incarcerated femoral hernia containing ipsilateral fallopian tube.", "content": "Incarcerated femoral hernia containing ipsilateral fallopian tube. Femoral hernias are more common in women and lead to a substantial higher rate for an emergency operation, due to strangulation. Incarcerated femoral hernia with fallopian tube as a content is an extremely rare condition. A 20-year-old woman presented to the emergency department complaining of a 6-day right groin swelling, which became painful and tender to palpation during the last 48 hours. Preoperative ultrasonography detected an oedematous hernia sac, above the femoral vessels, suggesting the presence of an incarcerated femoral hernia. The patient eventually underwent emergency surgery and the diagnosis of a strangulated femoral hernia sac, containing fallopian tube, was established. No resection of the uterine tube was performed and the hernia was repaired with polypropylene plug. The postoperative period was uneventful and the woman was discharged on the second postoperative day.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981264"}
{"pmid": "20981265", "title": "Rationale for possible targeting of histone deacetylase signaling in cancer diseases with a special reference to pancreatic cancer.", "content": "Rationale for possible targeting of histone deacetylase signaling in cancer diseases with a special reference to pancreatic cancer. There is ongoing interest to identify signaling pathways and genes that play a key role in carcinogenesis and the development of resistance to antitumoral drugs. Given that histone deacetylases (HDACs) interact with various partners through complex molecular mechanims leading to the control of gene expression, they have captured the attention of a large number of researchers. As a family of transcriptional corepressors, they have emerged as important regulators of cell differentiation, cell cycle progression, and apoptosis. Several HDAC inhibitors (HDACis) have been shown to efficiently protect against the growth of tumor cells in vitro as well as in vivo. The pancreatic cancer which represents one of the most aggressive cancer still suffers from inefficient therapy. Recent data, although using in vitro tumor cell cultures and in vivo chimeric mouse model, have shown that some of the HDACi do express antipancreatic tumor activity. This provides hope that some of the HDACi could be potential efficient anti-pancreatic cancer drugs. The purpose of this review is to analyze some of the current data of HDACi as possible targets of drug development and to provide some insight into the current problems with pancreatic cancer and points of interest for further study of HDACi as potential molecules for pancreatic cancer adjuvant therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981265"}
{"pmid": "20981266", "title": "An Allergen Portrait Gallery: Representative Structures and an Overview of IgE Binding Surfaces.", "content": "An Allergen Portrait Gallery: Representative Structures and an Overview of IgE Binding Surfaces. Recent progress in the biochemical classification and structural determination of allergens and allergen-antibody complexes has enhanced our understanding of the molecular determinants of allergenicity. Databases of allergens and their epitopes have facilitated the clustering of allergens according to their sequences and, more recently, their structures. Groups of similar sequences are identified for allergenic proteins from diverse sources, and all allergens are classified into a limited number of protein structural families. A gallery of experimental structures selected from the protein classes with the largest number of allergens demonstrate the structural diversity of the allergen universe. Further comparison of these structures and identification of areas that are different from innocuous proteins within the same protein family can be used to identify features specific to known allergens. Experimental and computational results related to the determination of IgE binding surfaces and methods to define allergen-specific motifs are highlighted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981266"}
{"pmid": "20981267", "title": "Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets.", "content": "Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets. Arsenic is a toxic metalloid that causes skin cancer and binds to cysteine residues-a property that could be used to infer arsenic responsiveness of a target protein. Non-synonymous Single Nucleotide Polymorphisms (nsSNPs) result in amino acid substitutions and may alter arsenic binding with cysteine residues. Thus, the objective of this investigation was to identify and analyze nsSNPs that lead to substitutions to or from cysteine residues as an indication of increased or decreased arsenic responsiveness. We hypothesize that integration of data on molecular impacts of nsSNPs and arsenic-gene relationships will identify nsSNPs that could serve as arsenic responsiveness markers. We have analyzed functional and structural impacts data for 5,811 nsSNPs linked to 1,224 arsenic-annotated genes. In addition to the identified candidate nsSNPs for increased or reduced arsenic responsiveness, we observed i) a nsSNP that results in the breakage of a disulfide bond, as candidate marker for reduced arsenic responsiveness of KLK7, a secreted serine protease participate in normal shedding of the skin; and ii) 6 pairs of vicinal cysteines in KLK7 protein that could be binding sites for arsenic. In summary, our analysis identified non-synonymous SNPs that could be used to evaluate responsiveness of a protein target to arsenic. In particular, an epidermal expressed serine protease with crucial function in normal skin physiology was prioritized on the basis of abundance of vicinal cysteines for further research on arsenic-induced keratinocyte carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981267"}
{"pmid": "20981268", "title": "Expression of metabolic, tissue remodeling, oxidative stress, and inflammatory pathways in mammary tissue during involution in lactating dairy cows.", "content": "Expression of metabolic, tissue remodeling, oxidative stress, and inflammatory pathways in mammary tissue during involution in lactating dairy cows. Histological and functional changes associated with involution in the mammary gland are partly regulated by changes in gene expression. At 42 d postpartum, Holstein cows underwent a period of 5 d during which they were milked 1X daily until complete cessation of milking. Percutaneous mammary biopsies (n = 5/time point) were obtained on d 1, 5, 14, and 21 relative to the start of 1X milking for transcript profiling via qPCR of 57 genes associated with metabolism, apoptosis/proliferation, immune response/inflammation, oxidative stress, and tissue remodeling. Not surprisingly, there was clear downregulation of genes associated with milk fat synthesis (FASN, ACACA, CD36, FABP3, SCD) and lipid-related transcription regulation (SREBF1, SREBF2). Similar to milk fat synthesis-related genes, those encoding proteins required for glucose uptake (SLC2A1), casein synthesis (CSN2, CSN3), and lactose synthesis (LALBA) decreased during involution. Unlike metabolic genes, those associated with immune response and inflammation (C3, LTF, SAA3), oxidative stress (GPX1, SOD2), and pro-inflammatory cytokine signaling (SPP1, TNF) increased to peak levels by d 14 from the start of 1X milking. These adaptations appeared to be related with tissue remodeling as indicated by upregulation of proteins encoding matrix proteinases (MMP2), IGFBP3, and transcriptional regulation of apoptosis/cell proliferation (MYC). In contrast, the concerted upregulation of STAT3, TGFB1, and TGFB1R during the first 14 d was suggestive of an activation of these signaling pathways probably as an acute response to regulate differentiation and/or mammary cell survival upon the onset of a marked pro-inflammatory and oxidative stress response induced by the gradual reduction in milk removal. Results suggest a central role of STAT3, MYC, PPARG, SREBF1, and SREBF2 in regulating concerted alterations in metabolic and cell survival mechanisms, which were induced partly via oxidative stressed-triggered inflammation and the decline in metabolic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981268"}
{"pmid": "20981270", "title": "Understanding of Abdominal Compartment Syndrome among Pediatric Healthcare Providers.", "content": "Understanding of Abdominal Compartment Syndrome among Pediatric Healthcare Providers. Background. The sparse reporting of abdominal compartment syndrome (ACS) in the pediatric literature may reflect inadequate awareness and recognition among pediatric healthcare providers (HCP). Purpose. To assess awareness of ACS, knowledge of the definition and intraabdominal pressure (IAP) measurement techniques used among pediatric HCP. Method. A written survey distributed at two pediatric critical care conferences. Results. Forty-seven percent of 1107 questionnaires were completed. Participants included pediatric intensivists, pediatric nurses, and others. Seventy-seven percent (n = 513) of participants had heard of ACS. Only 46.8% defined ACS correctly. The threshold IAP value used to define ACS was variable among participants. About one-quarter of participants (83/343), had never measured IAP. Conclusion. Twenty-three percent of HCP surveyed were unaware of ACS. Criteria used to define ACS were variable. Focused education on recognition of ACS and measuring IAP should be promoted among pediatric HCP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981270"}
{"pmid": "20981271", "title": "Two-hour lactate clearance predicts negative outcome in patients with cardiorespiratory insufficiency.", "content": "Two-hour lactate clearance predicts negative outcome in patients with cardiorespiratory insufficiency. Objective. To evaluate 2-hour lactate clearance as a prognostic marker in acute cardiorespiratory insufficiency. Design. Prospective observational study. Setting. Emergency Department (ED) and 16-bed medical High Dependency Unit (HDU). Methods and Main Results. 95 consecutive admissions from the ED for acute cardiorespiratory insufficiency were prospectively enrolled. Arterial lactate concentration was assessed at ED arrival and 1, 2, 6, and 24 hours later. The predictive value of 2-hour lactate clearance was evaluated for negative outcomes defined as hospital mortality or need for endotracheal intubation versus positive outcomes defined as discharge or transfer to a general medical ward. Logistic regression and ROC curves found 2-hour lactate clearance >15% was a strong predictor of negative outcome (P < .0001) with a sensitivity of 86% (95%CI = 67%-95%) and a specificity of 91% (95%CI = 82%-96%), Positive predictive value was 80% (95%CI = 61%-92%), and negative predictive value was 92% (95%CI = 84%-98%). Conclusions. Systematic monitoring of lactate clearance at 2 hours can be used in to identify patients at high risk of negative outcome and perhaps to tailor more aggressive therapy. Equally important is that a 2-hour lactate clearance >15% is highly predictive of positive outcome and may reassure clinicians that the therapeutic approach is appropriate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981271"}
{"pmid": "20981272", "title": "Increased Survivorship and Altered Cytokine Profile from Treatment of Influenza A H1N1-Infected Mice with Ekybion: A Drug Complex of Natural Extracts and Inorganic Compounds.", "content": "Increased Survivorship and Altered Cytokine Profile from Treatment of Influenza A H1N1-Infected Mice with Ekybion: A Drug Complex of Natural Extracts and Inorganic Compounds. Ekybion is a drug complex of 16 natural extracts and inorganic compounds designed to treat a variety of respiratory pathogens of bacterial and viral origin. It is licensed throughout Europe for the treatment of respiratory tract infections from equine parainfluenza type 3 and equine herpes virus type 1 in equine stables. The purpose of this paper was to test the efficacy of Ekybion on a well-developed animal model of influenza A infection and determine a mode of action. Experiments were performed with Balb/c mice infected with a lethal dose of influenza A/PR/8/34 H1N1 virus and treated with nebulized Ekybion every 8 h in a time-dependant or dose-dependant fashion. These experiments showed that mice treated prior to infection with Ekybion had a higher survival rates (~46%) compared with untreated animals (~0%). Paradoxically, these mice showed no significant difference in lung virus titer or weight loss. There was, however, a decrease in the level of GM-CSF, IL-6, and G-CSF cytokines in the lungs of Ekybion-treated, infected mice. It is possible that decreases in proinflammatory cytokines may have contributed to increased survivorship in Ekybion-treated influenza-infected mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981272"}
{"pmid": "20981273", "title": "Investigation of single and multidomain Pb(In(0.5)Nb(0.5))O(3)-Pb(Mg(1∕3)Nb(2∕3))O(3)-PbTiO(3) crystals with mm2 symmetry.", "content": "Investigation of single and multidomain Pb(In(0.5)Nb(0.5))O(3)-Pb(Mg(1∕3)Nb(2∕3))O(3)-PbTiO(3) crystals with mm2 symmetry. The piezoelectric properties of Pb(In(0.5)Nb(0.5))O(3)-Pb(Mg(1∕3)Nb(2∕3))O(3)-PbTiO(3) crystals with various engineered domain configurations were investigated. Rhombohedral and monoclinic∕orthorhombic crystals poled along their crystallographic [011] directions were found to possess macroscopic mm2 symmetry, with \"2R\" and \"1O\" domain, respectively. Crystals with the \"2R\" domain configuration were found to exhibit high extensional piezoelectric coefficients d(33) (∼1300 pC∕N) and d(32) (∼-1680 pC∕N), while crystals with the \"1O\" configuration possessed high shear coefficients d(15) (∼3500 pC∕N) and d(24) (∼2070 pC∕N), with relatively low extensional piezoelectric coefficients d(33) (∼340 pC∕N) and d(32) (∼-260 pC∕N). The observed results were explained by \"polarization rotation\" model, as related to their respective domain configurations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981273"}
{"pmid": "20981269", "title": "A grounded theory study of homeopathic practitioners' perceptions and experiences of the homeopathic consultation.", "content": "A grounded theory study of homeopathic practitioners' perceptions and experiences of the homeopathic consultation. Research into the homeopathic consultation has largely focused on patients' experiences, although the practitioner is a crucial component of the therapeutic context and may have an important part in optimizing health outcomes. Therefore the aim of this qualitative research was to gain an in-depth understanding of homeopathic practitioners' perceptions and experiences of the consultation. Medical and non-medical homeopaths were sampled from the registers of the Faculty and Society of Homeopaths. Two phases of data collection were employed. Phase 1 used in depth face-to-face interviews enabling the development of an initial model of the homeopathic consultation. Phase 2 involved observations of homeopathic consultations and practitioner reflective diaries in order to confirm, refute, or enlarge the model. Using the constant comparative method of grounded theory five main categories emerged, exploring the journey, finding the level, responding therapeutically, understanding self, and connecting, forming a model entitled \"a theoretical model of a UK classical homeopathic consultation\" which describes how homeopaths view and enact the consultation process. This study suggests that the process of identifying and prescribing the remedy is embedded in the consultation, highlighting the interconnectedness of the whole homeopathic consultation and aspects of the consultation that are unique and specific to homeopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981269"}
{"pmid": "20981274", "title": "High-resolution coregistered intravascular imaging with integrated ultrasound and optical coherence tomography probe.", "content": "High-resolution coregistered intravascular imaging with integrated ultrasound and optical coherence tomography probe. We report an integrated ultrasound (US) and optical coherence tomography (OCT) probe and system for intravascular imaging. The dual-function probe is based on a 50 MHz focused ring US transducer, with a centric hole for mounting OCT probe. The coaxial US and light beams are steered by a 45° mirror to enable coregistered US∕OCT imaging simultaneously. Lateral resolution of US is improved due to focused ultrasonic beam. Mirror effects on US were investigated and invitro imaging of a rabbit aorta has been carried out. The combined US-OCT system demonstrated high resolution in visualizing superficial arterial structures while retaining deep penetration of ultrasonic imaging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981274"}
{"pmid": "20981276", "title": "Germinal Cell Aplasia in Kif18a Mutant Male Mice Due to Impaired Chromosome Congression and Dysregulated BubR1 and CENP-E.", "content": "Germinal Cell Aplasia in Kif18a Mutant Male Mice Due to Impaired Chromosome Congression and Dysregulated BubR1 and CENP-E. Chromosomal instability during cell division frequently causes cell death or malignant transformation. Orderly chromosome congression at the metaphase plate, a paramount process to vertebrate mitosis and meiosis, is controlled by a number of molecular regulators, including kinesins. Kinesin-8 (Kif18A) functions to control mitotic chromosome alignment at the mid-zone by negative regulation of kinetochore oscillation. Here the authors report that disrupting Kif18a function results in complete sterility in male but not in female mice. Histological examination reveals that Kif18a(-/-) testes exhibit severe developmental impairment of seminiferous tubules. Testis atrophy in Kif18a(-/-) mice is caused by perturbation of microtubule dynamics and spindle pole integrity, leading to chromosome congression defects during mitosis and meiosis. Depletion of KIF18A via RNAi causes mitotic arrest accompanied by unaligned chromosomes and increased microtubule nucleating centers in both GC-1 and HeLa cells. Prolonged depletion of KIF18A causes apoptosis due to perturbed microtubule dynamics. Further studies reveal that KIF18A silencing results in degradation of CENP-E and BubR1, which is accompanied by premature sister chromatid separation. KIF18A physically interacts with BubR1 and CENP-E, and this interaction is modulated during mitosis. Combined, the studies indicate that KIF18A is essential for normal chromosome congression during cell division and that the absence of KIF18A function causes severe defects in microtubule dynamics, spindle integrity, and checkpoint activation, leading to germinal cell aplasia in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981276"}
{"pmid": "20981275", "title": "Electromyogenic Artifacts and Electroencephalographic Inferences Revisited.", "content": "Electromyogenic Artifacts and Electroencephalographic Inferences Revisited. Recent years have witnessed a renewed interest in using oscillatory brain electrical activity to understand the neural bases of cognition and emotion. Electrical signals originating from pericranial muscles represent a profound threat to the validity of such research. Recently, McMenamin et al (2010) examined whether independent component analysis (ICA) provides a sensitive and specific means of correcting electromyogenic (EMG) artifacts. This report sparked the accompanying commentary (Olbrich, Jödicke, Sander, Himmerich & Hegerl, in press), and here we revisit the question of how EMG can alter inferences drawn from the EEG and what can be done to minimize its pernicious effects. Accordingly, we briefly summarize salient features of the EMG problem and review recent research investigating the utility of ICA for correcting EMG and other artifacts. We then directly address the key concerns articulated by Olbrich and provide a critique of their efforts at validating ICA. We conclude by identifying key areas for future methodological work and offer some practical recommendations for intelligently addressing EMG artifact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981275"}
{"pmid": "20981277", "title": "Ethical Conduct in Research Involving Human Beings In Brazil: Diagnosis of Research Ethics Committee.", "content": "Ethical Conduct in Research Involving Human Beings In Brazil: Diagnosis of Research Ethics Committee. OBJECTIVE: Diagnose ethical conduct in research involving human beings in Brazil and the last 10 years of activity by the Human Research Ethics Committee of the Health Department - Federal District - CEP/SES/DF. METHODS: This work was based on a documentary research, descriptive and retrospective. It examined the database containing records of cases brought before the CEP/SES/DF, corresponding the period of June 1997 to December 2007. Results were generated in Excel program, version 2007. RESULTS: CEP/SES/DF has presented increasing number of research projects submitted to appreciation (n = 1129), composing: 90.4% approved 1.7% disapproved, 7.4% removed/filed and 0.5% excluded. Of these projects, 83% belonged to Group III, 18% multi-centered projects and 10% protocols with foreign participation. Time for approval has decreased over the years (30 to 60 days). Frequent pendencies: End of Free and Informed Consent (30%), Cover Sheet (25%), Methodology (20%), Curriculum vitae (12%), Budget (9%), and Others (4%). CONCLUSION: The assessment of the CEP/SES/DF activities, during a ten-year period has shown its commitment to the legitimacy of research ethics review and scientific production SES/DF. There were some weaknesses such as difficulty in monitoring the accompaniment of the research; interruption of works due to adverse drug reaction; gaps or errors in the protocol submitted by the researcher. These situations are the achieving targets for the elaboration of specific criteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981277"}
{"pmid": "20981278", "title": "Physical Activity and Adherence to Mediterranean Diet Increase Total Antioxidant Capacity: The ATTICA Study.", "content": "Physical Activity and Adherence to Mediterranean Diet Increase Total Antioxidant Capacity: The ATTICA Study. We studied the association of physical activity and adherence to the Mediterranean diet, in total antioxidant capacity (TAC). A random sample of 1514 men and 1528 women was selected from Attica region. Physical activity was assessed with a translated version of the validated \"International Physical Activity Questionnaire\" (iPAQ), and dietary intake through a validated Food Frequency Questionnaire (FFQ). Adherence to the Mediterranean diet was assessed by the MedDietScore that incorporated the inherent characteristics of this diet. TAC was positively correlated with the degree of physical activity (P < .05). TAC was also positively correlated with MedDietScore (r = 0.24, P < .001). Stratified analysis by diet status revealed that the most beneficial results were observed to highly active people as compared to inactive, who also followed the Mediterranean diet (288 ± 70 μmol/L, 230 ± 50 μmol/L, resp.), after adjusting for various confounders. Increased physical activity and greater adherence to the Mediterranean diet were associated with increased total antioxidant capacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981278"}
{"pmid": "20981279", "title": "CpG oligodeoxynucleotides enhance the efficacy of adoptive cell transfer using tumor infiltrating lymphocytes by modifying the Th1 polarization and local infiltration of Th17 cells.", "content": "CpG oligodeoxynucleotides enhance the efficacy of adoptive cell transfer using tumor infiltrating lymphocytes by modifying the Th1 polarization and local infiltration of Th17 cells. Adoptive cell transfer immunotherapy using tumor infiltrating lymphocytes (TILs) was an important therapeutic strategy against tumors. But the efficacy remains limited and development of new strategies is urgent. Recent evidence suggested that CpG-ODNs might be a potent candidate for tumor immunotherapy. Here we firstly reported that CpG-ODNs could significantly enhance the antitumor efficacy of adoptively transferred TILs in vivo accompanied by enhanced activity capacity and proliferation of CD8(+) T cells and CD8(+) T cells, as well as a Th1 polarization immune response. Most importantly, we found that CpG-ODNs could significantly elevate the infiltration of Th17 cells in tumor mass, which contributed to anti-tumor efficacy of TILs in vivo. Our findings suggested that CpG ODNs could enhance the anti-tumor efficacy of adoptively transferred TILs through modifying Th1 polarization and local infiltration of Th17 cells, which might provide a clue for developing a new strategy for ACT based on TILs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981279"}
{"pmid": "20981281", "title": "Xanthogranulomatous salpingitis associated with a large uterine leiomyoma.", "content": "Xanthogranulomatous salpingitis associated with a large uterine leiomyoma. A case of xanthogranulomatous salpingitis (XGS) associated with a large uterine leiomyoma in a 50-year-old woman is presented. Xanthogranulomatous inflammation is an uncommon form of chronic inflammation that is destructive to affected organs. It is characterized by the presence of lipid-filled macrophages with admixed lymphocytes, plasma cells, and neutrophils. A review of the literature revealed that most patients with XGS have a clinical history of long-standing pelvic inflammatory disease (PID) or, less often, endometriosis. We report a case lacking a history of either PID or endometriosis but with a concurrent large uterine leiomyoma. Although the exact etiology in this case was not clear, the leiomyoma may have played a contributory role in pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981281"}
{"pmid": "20981282", "title": "Total laparoscopic conservative surgery for an intramural ectopic pregnancy.", "content": "Total laparoscopic conservative surgery for an intramural ectopic pregnancy. A 38-year-old woman, gravida 3, para 1 with a history of a left salpingectomy for an ectopic pregnancy was admitted for treatment of a presumed ectopic pregnancy. Transvaginal sonography revealed an ill-defined gestational sac and fetal heart beat within the fundal myometrium adjacent to the left cornua. Laparoscopy was performed for a suspected left cornual pregnancy or intramural pregnancy. A cystic mass 3 cm in diameter was visible within the fundal myometrium. Total laparoscopic removal of the gestational sac was performed, and the uterus was preserved. Pathologic evaluation of the excised mass demonstrated chorionic villi involving the myometrium. In the literature, only one other case describing the laparoscopic removal of an intramural pregnancy has been reported. However, in the prior report, the patient still required hysterectomy after conservative surgery. Therefore, this is the first report of the successful treatment of an intramural pregnancy exclusively with laparoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981282"}
{"pmid": "20981280", "title": "The role of the IL-12 cytokine family in directing T-cell responses in oral candidosis.", "content": "The role of the IL-12 cytokine family in directing T-cell responses in oral candidosis. Candida albicans is an opportunistic fungal pathogen that normally exists as a harmless commensal in humans. In instances where host debilitation occurs, Candida can cause a range of clinical infections, and whilst these are primarily superficial, effecting mucosal membranes, systemic infections can develop in severely immunocompromised individuals. The mechanism of host immunity during commensal carriage of C. albicans has been intensively studied. In this paper, we present the most recent information concerning host recognition of C. albicans leading to cytokine production and the subsequent T-cell responses generated in response to C. albicans. Particular focus is given to the role of the IL-12 cytokine family including IL-12, IL-23, IL-27, and IL-35, in host immunity to Candida. CD4(+) T-cells are considered crucial in the regulation of immunity and inflammation. In this regard, the role of Th1/2, helper cells, together with the recently identified Th17 and Treg cells in candidosis will be discussed. Understanding the detailed mechanisms that underlie host immunity to Candida not only will be of benefit in terms of the infections caused by this organism but could also be exploited in the development of therapeutic interventions for other diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981280"}
{"pmid": "20981283", "title": "Long-Term Gynecological Outcomes in Women with Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency.", "content": "Long-Term Gynecological Outcomes in Women with Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency. Background. Our knowledge on long-term outcome in CAH remains incomplete. Methods. In a prospective study (33 CAH patients, 33 age-matched controls), reproductive outcomes, self-rating of genital appearance and function, and sexuality were correlated to degree of initial virilisation, genotype, and surgery. Results. Patients had larger median clitoral lengths (10.0 mm [range 2-30] versus 3.5 [2-8], P < .001), shorter vaginal length (121 mm [100-155] versus 128 [112-153], P = .12), lower uterine volumes (29.1 ml [7.5-56.7] versus 47.4 [15.9-177.5], P = .009), and higher ovarian volumes (4.4 ml [1.3-10.8] versus 2.8 [0.6-10.8], P = .09) than controls. Satisfaction with genital appearance was lower and negatively correlated to degree of initial virilisation (r(s) = ≤-0.39, P ≤ .05). More patients had never had intercourse (P = .001), and age at 1st intercourse was higher (18 yrs versus 16 yrs, P = .02). Conclusion. Despite overall acceptable cosmetic results, reproductive outcomes were suboptimal, supporting that multidisciplinary teams should be involved in adult follow up of CAH patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981283"}
{"pmid": "20981284", "title": "Functional Promiscuity of Homologues of the Bacterial ArsA ATPases.", "content": "Functional Promiscuity of Homologues of the Bacterial ArsA ATPases. The ArsA ATPase of E. coli plays an essential role in arsenic detoxification. Published evidence implicates ArsA in the energization of As(III) efflux via the formation of an oxyanion-translocating complex with ArsB. In addition, eukaryotic ArsA homologues have several recognized functions unrelated to arsenic resistance. By aligning ArsA homologues, constructing phylogenetic trees, examining ArsA encoding operons, and estimating the probable coevolution of these homologues with putative transporters and auxiliary proteins unrelated to ArsB, we provide evidence for new functions for ArsA homologues. They may play roles in carbon starvation, gas vesicle biogenesis, and arsenic resistance. The results lead to the proposal that ArsA homologues energize four distinct and nonhomologous transporters, ArsB, ArsP, CstA, and Acr3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981284"}
{"pmid": "20981285", "title": "Gadolinium Enhanced MR Coronary Vessel Wall Imaging at 3.0 Tesla.", "content": "Gadolinium Enhanced MR Coronary Vessel Wall Imaging at 3.0 Tesla. Purpose. We evaluated the influence of the time between low-dose gadolinium (Gd) contrast administration and coronary vessel wall enhancement (LGE) detected by 3T magnetic resonance imaging (MRI) in healthy subjects and patients with coronary artery disease (CAD). Materials and Methods. Four healthy subjects (4 men, mean age 29 ± 3 years and eleven CAD patients (6 women, mean age 61 ± 10 years) were studied on a commercial 3.0 Tesla (T) whole-body MR imaging system (Achieva 3.0 T; Philips, Best, The Netherlands). T1-weighted inversion-recovery coronary magnetic resonance imaging (MRI) was repeated up to 75 minutes after administration of low-dose Gadolinium (Gd) (0.1 mmol/kg Gd-DTPA). Results. LGE was seen in none of the healthy subjects, however in all of the CAD patients. In CAD patients, fifty-six of 62 (90.3%) segments showed LGE of the coronary artery vessel wall at time-interval 1 after contrast. At time-interval 2, 34 of 42 (81.0%) and at time-interval 3, 29 of 39 evaluable segments (74.4%) were enhanced. Conclusion. In this work, we demonstrate LGE of the coronary artery vessel wall using 3.0 T MRI after a single, low-dose Gd contrast injection in CAD patients but not in healthy subjects. In the majority of the evaluated coronary segments in CAD patients, LGE of the coronary vessel wall was already detectable 30-45 minutes after administration of the contrast agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981285"}
{"pmid": "20981288", "title": "Newly developed fully covered metal stent for unresectable malignant biliary stricture.", "content": "Newly developed fully covered metal stent for unresectable malignant biliary stricture. We herein report two patients with unresectable malignant biliary stricture who underwent stenting with a newly developed fully-covered metal stent. In the first case of lower-middle bile duct cancer, a stent was placed through the stenosis. In the second case of middle bile duct stricture due to lymph node metastases from gallbladder cancer, a stent was placed in the bile duct across the stenosis. No procedure-related complications were observed. Unevenness of the outer surface and a low shortening ratio are expected to lessen the occurrence of complications characteristic of covered metal stents such as stent migration and bile duct kinking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981288"}
{"pmid": "20981289", "title": "Adhesion of Pathogenic Bacteria to Food Contact Surfaces: Influence of pH of Culture.", "content": "Adhesion of Pathogenic Bacteria to Food Contact Surfaces: Influence of pH of Culture. The adhesion of Aeromonas hydrophila, Escherichia coli O157:H7, Salmonella Enteritidis, and Staphylococcus aureus to hydrophobic and hydrophilic surfaces in cultures with different pHs (6, 7, and 8) was studied. The results indicated that the type of material had no effect on the attachment capacity of microorganisms, while environmental pH influenced the adhesion of A. hydrophila, E. coli, and S. aureus to both solid substrates. The attachment of S. Enteritidis (P > .05) was not affected by the type of substrate or the culture pH, whereas E. coli displayed the weakest affinity for both polystyrene and glass surfaces. No correlation was established between the physicochemical properties of the materials, or the bacterial and the rate of bacterial adhesion, except for S. aureus. Photomicrographs have shown that surfaces were contaminated by small clusters of S. Enteritidis while S. aureus invaded the food contact surfaces in the form of small chains or cell aggregates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981289"}
{"pmid": "20981287", "title": "Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole.", "content": "Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole. Nitroheterocyclic compounds are widely used as therapeutic agents against a variety of protozoan and bacterial infections. However, the literature on these compounds, suspected of being carcinogens, is widely controversial. In this study, cytotoxic and genotoxic potential of three drugs, Nifurtimox (NFX), Benznidazole (BNZ), and Metronidazole (MTZ) was re-evaluated by different assays. Only NFX reduces survival rate in actively proliferating cells. The compounds are more active for base-pair substitution than frameshift induction in Salmonella; NFX and BNZ are more mutagenic than MTZ; they are widely dependent from nitroreduction whereas microsomal fraction S9 weakly affects the mutagenic potential. Comet assay detects BNZ- and NFX-induced DNA damage at doses in the range of therapeutically treated patient plasma concentration; BNZ seems to mainly act through ROS generation whereas a dose-dependent mechanism of DNA damaging is suggested for NFX. The lack of effects on mammalian cells for MTZ is confirmed also in MN assay whereas MN induction is observed for NFX and BNZ. The effects of MTZ, that shows comparatively low reduction potential, seem to be strictly dependent on anaerobic/hypoxic conditions. Both NFX and BNZ may not only lead to cellular damage of the infective agent but also interact with the DNA of mammalian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981287"}
{"pmid": "20981286", "title": "Roles of beta2- and beta3-adrenoceptor polymorphisms in hypertension and metabolic syndrome.", "content": "Roles of beta2- and beta3-adrenoceptor polymorphisms in hypertension and metabolic syndrome. Hypertension, diabetes mellitus (especially type 2 diabetes mellitus), metabolic syndrome and obesity are rapidly growing public health problems. Sympathetic nerve activation is observed in obesity, hypertension and diabetes mellitus, which have strong genetic as well as environmental determinants. Reduced energy expenditure and resting metabolic rate are predictive of weight gain, and the sympathetic nervous system participates in regulating energy balance through thermogenesis. The thermogenic effects of catecholamines in obesity have been mainly mediated via the β2- and β3-adrenergic receptors in humans. Further, β2-adrenoceptors importantly influence vascular reactivity and may regulate blood pressure. Genetic polymorphistns of the β-adrenoceptor gene have been shown to alter the function of several adrenoceptor subtypes and thus to modify the response to catecholamine. β2-adrenoceptor polymorphisms (Arg16Gly, Gln27Glu, and Thr164Ile) have been studied in relation to hypertension. Genetic variations in the β3-adrenoceptor (i.e. Try64Arg variant) are also associated with both obesity and hypertension. However, the precise relationships of the polymorphisms of β2- and β3-adrenoceptor genes with sympathetic nervous system activity, hypertension, and metabolic syndrome have not been fully clarified. This paper will discuss the current topics involving the influence of the sympathetic nervous system and β2- and β3- adrenoceptor polymorphisms in hypertension and metabolic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981286"}
{"pmid": "20981290", "title": "Multimodality imaging of chronic ischemia.", "content": "Multimodality imaging of chronic ischemia. Although ischemic cardiomyopathy is commonly caused by chronic obstructive coronary disease, the mechanism of the cause is still under investigation. We present echocardiographic strain, magnetic resonance, and histology findings in a chronic ischemia model in preclinical study. This case illustrates the features of multimodality imaging in chronic obstructive coronary disease and gives us great insight into understanding the mechanism of ischemic cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981290"}
{"pmid": "20981292", "title": "Surface lipids as multifunctional mediators of skin responses to environmental stimuli.", "content": "Surface lipids as multifunctional mediators of skin responses to environmental stimuli. Skin surface lipid (SSL) film is a mixture of sebum and keratinocyte membrane lipids, protecting skin from environment. Its composition is unique for the high percentage of long chain fatty acids, and of the polyterpenoid squalene, absent in other human tissues, and in non-human Primates sebum. Here, the still incomplete body of information on SSL as mediators of external chemical, physical, and microbial signals and stressors is revised, focusing on the central event of the continuous oxidative modification induced by the metabolic activity of residential and pathological microbial flora, natural or iatrogenic UV irradiation, exposure to chemicals and cosmetics. Once alpha-tocopherol and ubiquinol-10 antioxidant defences of SSL are overcome, oxidation of squalene and cholesterol gives rise to reactive by-products penetrating deeper into skin layers, to mediate local defensive inflammatory, photo-protective, immune reactions or, at higher concentrations, inducing local but also systemic immune depression, ultimately implicating skin cancerogenesis. Qualitative modifications of SSL represent a pathogenetic sign of diagnostic value in dermatological disorders involving altered sebum production, like pytiriasis versicolor, acne, atopic or seborrheic dermatitis, as well as photo-aging. Achievements of nutriceutical interventions aimed at restoring normal SSL composition and homeostasis are discussed, as feasible therapeutic goals and major means of photo-protection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981292"}
{"pmid": "20981291", "title": "Consensus in Guidelines for Evaluation of DSD by the Texas Children's Hospital Multidisciplinary Gender Medicine Team.", "content": "Consensus in Guidelines for Evaluation of DSD by the Texas Children's Hospital Multidisciplinary Gender Medicine Team. The Gender Medicine Team (GMT), comprised of members with expertise in endocrinology, ethics, genetics, gynecology, pediatric surgery, psychology, and urology, at Texas Children's Hospital and Baylor College of Medicine formed a task force to formulate a consensus statement on practice guidelines for managing disorders of sexual differentiation (DSD) and for making sex assignments. The GMT task force reviewed published evidence and incorporated findings from clinical experience. Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) was used to assess the quality of evidence presented in the literature for establishing evidence-based guidelines. The task force presents a consensus statement regarding specific diagnostic and therapeutic issues in the management of individuals who present with DSD. The consensus statement includes recommendations for (1) laboratory workup, (2) acute management, (3) sex assignment in an ethical framework that includes education and involvement of the parents, and (4) surgical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981291"}
{"pmid": "20981295", "title": "Inhibitory effect of chinese propolis on phosphatidylcholine-specific phospholipase C activity in vascular endothelial cells.", "content": "Inhibitory effect of chinese propolis on phosphatidylcholine-specific phospholipase C activity in vascular endothelial cells. To understand the mechanisms underlying the anti-inflammatory action of Chinese propolis, we investigated its effect on the activity of phosphatidylcholine-specific phospholipase C (PC-PLC) that plays critical roles in control of vascular endothelial cell (VEC) function and inflammatory responses. Furthermore, p53 and reactive oxygen species (ROS) levels and mitochondrial membrane potential (Δψm) were investigated. Our data indicated that treatment of Chinese propolis 6.25 and 12.5 μg/ml for 12 hours increased VEC viability obviously. Exposure to Chinese propolis 6.25, 12.5, and 25 μg/ml for 6 and 12 hours significantly decreased PC-PLC activity and p53 level, and ROS levels were depressed by Chinese propolis 12.5 μg/ml and 25 μg/ml dramatically. The Δψm of VECs was not affected by Chinese propolis at low concentration but disrupted by the propolis at 25 μg/ml significantly, which indicated that Chinese propolis depressed PC-PLC activity and the levels of p53 and ROS in VECs but disrupted Δψm at a high concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981295"}
{"pmid": "20981294", "title": "Animal models of typical heterotopic ossification.", "content": "Animal models of typical heterotopic ossification. Heterotopic ossification (HO) is the formation of marrow-containing bone outside of the normal skeleton. Acquired HO following traumatic events is a common and costly clinical complication. In contrast, hereditary HO is rarer, progressive, and life-threatening. Substantial effort has been directed towards understanding the mechanisms underlying HO and finding efficient treatments. However, one crucial limiting factor has been the lack of relevant animal models. This article reviews the major currently available animal models, summarizes some of the insights gained from these studies, and discusses the potential future challenges and directions in HO research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981294"}
{"pmid": "20981293", "title": "Causes and mechanisms of intrauterine hypoxia and its impact on the fetal cardiovascular system: a review.", "content": "Causes and mechanisms of intrauterine hypoxia and its impact on the fetal cardiovascular system: a review. Until today the role of oxygen in the development of the fetus remains controversially discussed. It is still believed that lack of oxygen in utero might be responsible for some of the known congenital cardiovascular malformations. Over the last two decades detailed research has given us new insights and a better understanding of embryogenesis and fetal growth. But most importantly it has repeatedly demonstrated that oxygen only plays a minor role in the early intrauterine development. After organogenesis has taken place hypoxia becomes more important during the second and third trimester of pregnancy when fetal growth occurs. This review will briefly adress causes and mechanisms leading to intrauterine hypoxia and their impact on the fetal cardiovascular system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981293"}
{"pmid": "20981296", "title": "The availability of a recombinant anti-SNAP antibody in VHH format amplifies the application flexibility of SNAP-tagged proteins.", "content": "The availability of a recombinant anti-SNAP antibody in VHH format amplifies the application flexibility of SNAP-tagged proteins. Antibodies are indispensable reagents in basic research, and those raised against tags constitute a useful tool for the evaluation of the biochemistry and biology of novel proteins. In this paper, we describe the isolation and characterization of a single-domain recombinant antibody (VHH) specific for the SNAP-tag, using Twist2 as a test-protein. The antibody was efficient in western blot, immunoprecipitation, immunopurification, and immunofluorescence. The sequence corresponding to the anti-SNAP has been subcloned for large-scale expression in vectors that allow its fusion to either a 6xHis-tag or the Fc domain of rabbit IgG2 taking advantage of a new plasmid that was specifically designed for VHH antibodies. The two different fusion antibodies were compared in immunopurification and immunofluorescence experiments, and the recombinant protein SNAP-Twist2 was accurately identified by the anti-SNAP Fc-VHH construct in the nuclear/nucleolar subcellular compartment. Furthermore, such localization was confirmed by direct Twist2 identification by means of anti-Twisit2 VHH antibodies recovered after panning of the same naïve phage display library used to isolate the anti-SNAP binders. Our successful localization of Twist2 protein using the SNAP-tag-based approach and the anti-Twist2-specific recombinant single-domain antibodies opens new research possibilities in this field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981296"}
{"pmid": "20981298", "title": "Reproductive technologies and genomic selection in cattle.", "content": "Reproductive technologies and genomic selection in cattle. The recent development of genomic selection induces dramatic changes in the way genetic selection schemes are to be conducted. This review describes the new context and corresponding needs for genomic based selection schemes and how reproductive technologies can be used to meet those needs. Information brought by reproductive physiology will provide new markers and new improved phenotypes that will increase the efficiency of selection schemes for reproductive traits. In this context, the value of the reproductive techniques including assisted embryo based reproductive technologies (Multiple Ovaluation Embryo Transfer and Ovum pick up associated to in vitro Fertilization) is also revisited. The interest of embryo typing is discussed. The recent results obtained with this emerging technology which are compatible with the use of the last generation of chips for genotype analysis may lead to very promising applications for the breeding industry. The combined use of several embryo based reproductive technologies will probably be more important in the near future to satisfy the needs of genomic selection for increasing the number of candidates and to preserve at the same time genetic variability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981298"}
{"pmid": "20981297", "title": "Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver.", "content": "Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver. Thiazolidinediones are a class of Peroxisome Proliferator Activated Receptor γ (PPARγ) agonists that reduce insulin resistance in type 2 diabetic patients. Although no detectable hepatic toxicity has been evidenced in animal studies during preclinical trials, these molecules have nevertheless induced hepatic adverse effects in some treated patients. The mechanism(s) of hepatotoxicity remains equivocal. Several studies have been conducted using PCR analysis and microarray technology to identify possible target genes and here we review the data obtained from various in vivo and in vitro experimental models. Although PPARγ is expressed at a much lower level in liver than in adipose tissue, PPARγ agonists exert various PPARγ-dependent effects in liver in addition to PPARγ-independent effects. Differences in effects are dependent on the choice of agonist and experimental conditions in rodent animal studies and in rodent and human liver cell cultures. These effects are much more pronounced in obese and diabetic liver. Moreover, our own recent studies have shown major interindividual variability in the response of primary human hepatocyte populations to troglitazone treatment, supporting the occurrence of hepatotoxicity in only some individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981297"}
{"pmid": "20981299", "title": "Orthodontic Bracket Manufacturing Tolerances and Dimensional Differences between Select Self-Ligating Brackets.", "content": "Orthodontic Bracket Manufacturing Tolerances and Dimensional Differences between Select Self-Ligating Brackets. In all manufacturing processes there are tolerances; however, orthodontic bracket manufacturers seldom state the slot dimensional tolerances. This experiment develops a novel method of analyzing slot profile dimensions using photographs of the slot. Five points are selected along each wall, and lines are fitted to define a trapezoidal slot shape. This investigation measures slot height at the slot's top and bottom, angles between walls, slot taper, and the linearity of each wall. Slot dimensions for 30 upper right central incisor self-ligating stainless steel brackets from three manufacturers were evaluated. Speed brackets have a slot height 2% smaller than the nominal 0.559 mm size and have a slightly convergent taper. In-Ovation brackets have a divergent taper at an average angle of 1.47 degrees. In-Ovation is closest to the nominal value of slot height at the slot base and has the smallest manufacturing tolerances. Damon Q brackets are the most rectangular in shape, with nearly 90-degree corners between the slot bottom and walls. Damon slot height is on average 3% oversized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981299"}
{"pmid": "20981300", "title": "The Relationship between the Transforming Growth Factor β1 T29C Gene Polymorphism and Left Ventricular Geometry and Function in Hypertensive Subjects.", "content": "The Relationship between the Transforming Growth Factor β1 T29C Gene Polymorphism and Left Ventricular Geometry and Function in Hypertensive Subjects. The distribution of the T29C TGFβ1 gene polymorphism was analyzed in 198 hypertensives with left ventricular hypertrophy (LVH) and in 235 hypertensives without LVH. Circulating TGFβ1 levels, procollagen type III levels, microalbuminuria, and left ventricular geometry and function were evaluated in all the hypertensives with LVH subgrouped according to T29C TGFβ1 gene polymorphism. Circulating TGFβ1 was evaluated by ELISA technique, procollagen type III by a specific radioimmunoassay, microalbuminuria by radioimmunoassay, and left ventricular geometry and function by echocardiography. All groups were comparable for gender, age, and sex. Regarding T29C TGFβ1 gene polymorphism, prevalence of TC or CC genotypes was significantly (P < .05) higher in hypertensives with LVH than hypertensives without LVH TC and CC LVH hypertensives were characterized by a higher prevalence of subjects with microalbuminuria (P < .05 TC and CC versus TT), by increased levels of TGFβ1, procollagen type III, urinary albumin excretion, LVM, LVM/h(2.7), and lower values of left ventricular ejection fraction (P < .05 TC and CC versus TT). Our data suggest that T29C TGFβ1 gene polymorphism was associated with clinical characteristics adequate to recognize a subset of LVH hypertensives with a higher severity of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981300"}
{"pmid": "20981301", "title": "Gene/Environment interaction in atherosclerosis: an example of clinical medicine as seen from the evolutionary perspective.", "content": "Gene/Environment interaction in atherosclerosis: an example of clinical medicine as seen from the evolutionary perspective. Evolutionary medicine is the application of evolution theory to understanding health and disease. It provides a complementary scientific approach to the present mechanistic explanations that dominate medical science, and particularly medical education. The chronic multifactorial disease of atherosclerosis clearly illustrates the Darwinian paradigm. Recent research, combining the effects of genes and environment, has provided surprising clues to the pathogenesis of this major public health problem. This example makes a strong case for recognizing evolution biology as a basic science for medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981301"}
{"pmid": "20981302", "title": "Genome-wide association study of coronary artery disease.", "content": "Genome-wide association study of coronary artery disease. Coronary artery disease (CAD) is a multifactorial disease with environmental and genetic determinants. The genetic determinants of CAD have previously been explored by the candidate gene approach. Recently, the data from the International HapMap Project and the development of dense genotyping chips have enabled us to perform genome-wide association studies (GWAS) on a large number of subjects without bias towards any particular candidate genes. In 2007, three chip-based GWAS simultaneously revealed the significant association between common variants on chromosome 9p21 and CAD. This association was replicated among other ethnic groups and also in a meta-analysis. Further investigations have detected several other candidate loci associated with CAD. The chip-based GWAS approach has identified novel and unbiased genetic determinants of CAD and these insights provide the important direction to better understand the pathogenesis of CAD and to develop new and improved preventive measures and treatments for CAD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981302"}
{"pmid": "20981303", "title": "Advances in diagnosis of respiratory virus infections.", "content": "Advances in diagnosis of respiratory virus infections. The diagnosis of respiratory virus infections has evolved substantially in recent years, with the emergence of new pathogens and the development of novel detection methods. While recent advances have improved the sensitivity and turn-around time of diagnostic tests for respiratory viruses, they have also raised important issues such as cost, and the clinical significance of detecting multiple viruses in a single specimen by molecular methods. This article reviews recent advances in specimen collection and detection methods for diagnosis of respiratory virus infections, and discusses the performance characteristics and limitations of these methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981303"}
{"pmid": "20981304", "title": "Noninvasive detection of left-ventricular systolic dysfunction by acoustic cardiography in atrial fibrillation.", "content": "Noninvasive detection of left-ventricular systolic dysfunction by acoustic cardiography in atrial fibrillation. Objectives. Assessment of left ventricular (LV) systolic function in patients with atrial fibrillation can be difficult. Acoustic cardiography provides several parameters for quantifying LV systolic function. We evaluated the ability of acoustic cardiography to detect LV systolic dysfunction in patients with and without atrial fibrillation. Design. We studied 194 patients who underwent acoustic cardiography and cardiac catheterization including measurement of angiographic ejection fraction (EF) and maximum LV dP/dt. LV systolic dysfunction was defined as LV maximum dP/dt <1600 mmHg/s. Acoustic cardiographic parameters included electromechanical activation time (EMAT) and the systolic dysfunction index (SDI). Results. Acoustic cardiography detected systolic dysfunction with high specificity and moderate sensitivity with similar performance to EF (sensitivity/specificity without afib: EMAT 30/96, SDI 40/90, EF at 35% 30/96; sensitivity/specificity with afib: EMAT 64/82, SDI 59/100, EF at 35% 45/82). Conclusions. Acoustic cardiography can be used for diagnosis of LV systolic dysfunction in atrial fibrillation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981304"}
{"pmid": "20981305", "title": "Vascular alterations and sexual function in systemic sclerosis.", "content": "Vascular alterations and sexual function in systemic sclerosis. Sexual dysfunction is common in systemic sclerosis (SSc). Male erectile dysfunction (MED) has been reported in around 80% of subjects and more than half of female patients fulfill criteria for diagnosis as female sexual arousal Disorder (FSAD). While some evidence supports a role for cavernosal fibrosis, abundant data suggest that MED is yet another clinical feature of SSc related to vasculopathy. The contribution of vasculopathy to the more complex issues of female sexual dysfunction is less clear. Inhibitors of Type V phosphodiesterase are effective in men with MED secondary to SSc. Limited study in women suggests inconsistent effects on behavior (frequency) but not on measures related to perfusion. Sexual activity is an important component of quality of life and an important domain for the caregiver to address; it is not clear that it warrants primary consideration as a consistent measure of scleroderma-related vasculopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981305"}
{"pmid": "20981307", "title": "An NOS3 Haplotype is Protective against Hypertension in a Caucasian Population.", "content": "An NOS3 Haplotype is Protective against Hypertension in a Caucasian Population. The endothelial nitric oxide synthase gene (NOS3) has been implicated in the development of hypertension, although the specific role of variants and haplotypes has not been clarified. In this study, the association of three polymorphisms (promoter T786C, intronic 4a/b, and nonsynonymous G894T) was tested in a case-control sample of 230 patients with essential hypertension and 306 healthy controls. Haplotype analysis was also performed. The mutant allele a(∗) of the 4a/b polymorphism showed a protective effect against hypertension under a dominant model (odds ratio = 0.64, 95% confidence interval (0.44-0.93)), although this effect was not significant after the adjustment for covariates (P = 0.06). The estimated frequency of the haplotype composed of the T786(∗), 4a(∗), and G894(∗) alleles was significantly higher in controls (5.5%) compared to cases (2%). These results indicate that although individual NOS3 polymorphisms are not associated with hypertension, a rare haplotype of the gene might be protective against the development of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981307"}
{"pmid": "20981310", "title": "Microscopic polyangiitis in systemic sclerosis.", "content": "Microscopic polyangiitis in systemic sclerosis. AAV in SSc is described from the point of view of MPA. Some of reported SSc cases with AAV are thought to exhibit the characteristic clinical manifestations of MPA, although ANCA positivity in SSc is uncommon. MPA is clinically characterized by a multisystemic disease such as RPGN, pulmonary hemorrhage, mononeuritis, and skin involvement, as well as other manifestations in conjunction with high levels of inflammatory activity such as high ESR or CRP. It is also characterized by a high frequency of MPO-ANCA, showing predominant pANCA by IIF. When rapid renal failure or RPGN with active urine sediments, pulmonary hemorrhage and/or systemic inflammatory manifestations are observed in patients with SSc having positive ANCA, the possibility of MPA should always be considered. If SSc patients with MPA have life-threatening visceral involvement such as the above clinical manifestations, the patients should be treated with induction therapy using cyclophosphamide, methotrexate, corticosteroids, or plasmapheresis, etc. according to the severity of the disease soon after the diagnosis of MPA. It is important not to overlook characteristic clinical manifestations of AAV during the course of the disease in SSc in order to diagnose MPA early.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981310"}
{"pmid": "20981308", "title": "Acne scars: pathogenesis, classification and treatment.", "content": "Acne scars: pathogenesis, classification and treatment. Acne has a prevalence of over 90% among adolescents and persists into adulthood in approximately 12%-14% of cases with psychological and social implications. Possible outcomes of the inflammatory acne lesions are acne scars which, although they can be treated in a number of ways, may have a negative psychological impact on social life and relationships. The main types of acne scars are atrophic and hypertrophic scars. The pathogenesis of acne scarring is still not fully understood, but several hypotheses have been proposed. There are numerous treatments: chemical peels, dermabrasion/microdermabrasion, laser treatment, punch techniques, dermal grafting, needling and combined therapies for atrophic scars: silicone gels, intralesional steroid therapy, cryotherapy, and surgery for hypertrophic and keloidal lesions. This paper summarizes acne scar pathogenesis, classification and treatment options.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981308"}
{"pmid": "20981306", "title": "Post testicular sperm maturational changes in the bull: important role of the epididymosomes and prostasomes.", "content": "Post testicular sperm maturational changes in the bull: important role of the epididymosomes and prostasomes. After spermatogenesis, testicular spermatozoa are not able to fertilize an oocyte, they must undergo sequential maturational processes. Part of these essential processes occurs during the transit of the spermatozoa through the male reproductive tract. Since the sperm become silent in terms of translation and transcription at the testicular level, all the maturational changes that take place on them are dependent on the interaction of spermatozoa with epididymal and accessory gland fluids. During the last decades, reproductive biotechnologies applied to bovine species have advanced significantly. The knowledge of the bull reproductive physiology is really important for the improvement of these techniques and the development of new ones. This paper focuses on the importance of the sperm interaction with the male reproductive fluids to acquire the fertilizing ability, with special attention to the role of the membranous vesicles present in those fluids and the recent mechanisms of protein acquisition during sperm maturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981306"}
{"pmid": "20981309", "title": "Pediatric sedation: a global challenge.", "content": "Pediatric sedation: a global challenge. Pediatric sedation is a challenge which spans all continents and has grown to encompass specialties outside of anesthesia, radiology and emergency medicine. All sedatives are not universally available and local and national regulations often limit the sedation practice to specific agents and those with specific credentials. Some specialties have established certification and credentials for sedation delivery whereas most have not. Some of the relevant sedation guidelines and recommendations of specialty organizations worldwide will be explored. The challenge facing sedation care providers moving forward in the 21st century will be to determine how to apply the local, regional and national guidelines to the individual sedation practices. A greater challenge, perhaps impossible, will be to determine whether the sedation community can come together worldwide to develop standards, guidelines and recommendations for safe sedation practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981309"}
{"pmid": "20981311", "title": "Bilateral serous retinal detachments associated with accelerated hypertensive choroidopathy.", "content": "Bilateral serous retinal detachments associated with accelerated hypertensive choroidopathy. Purpose. We report a case of hypertensive choroidopathy with bilateral serous retinal detachments. Patient. A 50-year-old man underwent bilateral serous retinal detachments. Retinal arteriolar narrowing, vascular tortuosity, and arteriovenous nicking were identified in both eyes. The blood pressure was 206/125 mmHg. The patient was diagnosed with bilateral hypertensive choroidopathy and treated with oral antihypertensive treatment. Results and discussion. One month after antihypertensive treatment, the serous retinal detachments resolved and the visual acuity improved. A patient with those findings should be considered as having hypertensive choroidopathy and treated as soon as possible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981311"}
{"pmid": "20981312", "title": "Scleroderma renal crisis: a pathology perspective.", "content": "Scleroderma renal crisis: a pathology perspective. Scleroderma renal crisis (SRC) is an infrequent but serious complication of systemic sclerosis (SSc). It is associated with increased vascular permeability, activation of coagulation cascade, and renin secretion, which may lead to the acute renal failure typically associated with accelerated hypertension. The histologic picture of SRC is that of a thrombotic microangiopathy process with prominent small vessel involvement manifesting as myxoid intimal changes, thrombi, onion skin lesions, and/or fibrointimal sclerosis. Renal biopsies play an important role in confirming the clinical diagnosis, excluding overlapping/superimposed diseases that might lead to acute renal failure in SSc patients, helping to predict the clinical outcome and optimizing patient management. Kidney transplantation may be the only treatment option available for a subset of SRC patients who develop end-stage renal failure despite aggressive angiotensin-converting enzyme inhibitor therapy. However, the posttransplant outcome for SSc patients is currently suboptimal compared to the general renal transplant population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981312"}
{"pmid": "20981313", "title": "Prevalence, Awareness, Treatment, and Control of Hypertension in Romania: Results of the SEPHAR Study.", "content": "Prevalence, Awareness, Treatment, and Control of Hypertension in Romania: Results of the SEPHAR Study. East European countries have reported high prevalence of Arterial Hypertension (AHT). In order to investigate the data for Romania, we firstly performed a national survey-the Study for the Evaluation of Prevalence of Hypertension and Cardiovascular Risk in Adult Population in Romania (SEPHAR). A representative population was selected using stratified proportional sampling, including 2017 adult subjects, ≥18 years old. The general prevalence of AHT was 44,92%, higher in men (50,17%) than in women (41,11%) (P < .0001) and predominant in rural areas (49,47%) in comparison to the urban ones (41,58%) (P < .02). AHT awareness attended 44,26%, rising with age, significantly lower in men (34,58%) than in women (52,8%) (P < .0006). We have found a 38,85% proportion of treated hypertensive persons, worse for men (30,11%) then for women (46,56%) (P < .003). The rate of AHT control was 19,88%, with no significant differences between gender. In conclusion, we estimated for Romania a high prevalence of AHT, a level of awareness and treatment lower than in many European countries and a rate of treatment control at the inferior limit of the European average. Males, characterized by a higher prevalence of AHT, were also less aware and less treated than women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981313"}
{"pmid": "20981314", "title": "Endosonography-guided biliary drainage with one-step placement of a newly developed fully covered metal stent followed by duodenal stenting for pancreatic head cancer.", "content": "Endosonography-guided biliary drainage with one-step placement of a newly developed fully covered metal stent followed by duodenal stenting for pancreatic head cancer. An 83-year-old man was admitted to our department, presenting with jaundice, fever, and nausea. CT revealed a pancreatic head tumor with duodenal invasion. Endoscopic transpapillary biliary drainage was unsuccessful due to stenosis at the second portion of the duodenum and tumor invasion to the papilla of Vater. Using a convex linear array echoendoscope, a fully-covered metal stent was placed across the puncture tract to bridge the duodenum and the bile duct. After improvement of jaundice, a duodenal metal stent was placed across the stricture of the duodenum. No procedure-related complications occurred. Neither migration nor obstruction of the two stents was observed during the three months followup period. Combination of ESBD using a fully covered metal stent and duodenal stenting is a feasible technique and possibly a less invasive treatment option for malignant biliary and duodenal obstruction compared to surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981314"}
{"pmid": "20981315", "title": "Penile involvement in Systemic Sclerosis: New Diagnostic and Therapeutic Aspects.", "content": "Penile involvement in Systemic Sclerosis: New Diagnostic and Therapeutic Aspects. Systemic Sclerosis (SSc) is a connective tissue disorder featuring vascular alterations and an immunological activation leading to a progressive and widespread fibrosis of several organs such as the skin, lung, gastrointestinal tract, heart, and kidney. Men with SSc are at increased risk of developing erectile dysfunction (ED) because of the evolution of early microvascular tissutal damage into corporeal fibrosis. The entity of penile vascular damage in SSc patients has been demonstrated by using Duplex ultrasonography and functional infra-red imaging and it is now clear that this is a true clinical entity invariably occurring irrespective of age and disease duration and constituting the ''sclerodermic penis\". Once-daily phosphodiesterase type-5 (PDE5) inhibitors improve both sexual function and vascular measures of cavernous arteries by improving surrogate markers of endothelial dysfunction, that is, plasma endothelin-1 and adrenomedullin levels, which may play a potential role in preventing progression of penile fibrosis and ED. Also, the beneficial effect of long-term PDE5i add-on therapy to SSc therapy in the treatment of Raynaud's phenomenon is described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981315"}
{"pmid": "20981316", "title": "Interleukin-6 as a potential therapeutic target for pulmonary arterial hypertension.", "content": "Interleukin-6 as a potential therapeutic target for pulmonary arterial hypertension. Interleukin-6 (IL-6) is a pleiotropic cytokine with a wide range of biologic activities in immune regulation, hematopoiesis, inflammation, and oncogenesis. Recent accumulating evidence indicates a pathologic role for IL-6 in promoting proliferation of both smooth muscle and endothelial cells in the pulmonary arterioles, resulting in development of pulmonary arterial hypertension (PAH). Here, we describe a patient with mixed connective tissue disease and severe, refractory PAH. Her functional activity and hemodynamic parameters dramatically responded to tocilizumab, a humanized monoclonal antibody to human IL-6 receptor, which was aimed at treating multicentric Castleman's disease. It appears that IL-6 blockade may hold promise as an adjunct drug in treatment of PAH in idiopathic form as well as in association with connective tissue disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981316"}
{"pmid": "20981318", "title": "Quercetin and Bornyl Acetate Regulate T-Lymphocyte Subsets and INF-γ/IL-4 Ratio In Utero in Pregnant Mice.", "content": "Quercetin and Bornyl Acetate Regulate T-Lymphocyte Subsets and INF-γ/IL-4 Ratio In Utero in Pregnant Mice. The objective of this study is to investigate the antiabortive effects of Quercetin and Bornvl Acetate and their immunological modulation at maternal-fetal interface. Lipopolysaccharide (LPS) was injected via tail vein to induce abortion in mice which received Quercetin and Bornvl Acetate at days 4-7 of gestation. Uterine CD4+/CD8+ T lymphocytes and IFN-γ/IL-4 of each group (n = 10) were detected by immunohistochemistry and enzyme-linked immunosorbent assay, respectively. The ratio of CD4+/CD8+ increased significantly (P < .01) in the uterus of LPS-induced abortion mice. In the Quercetin and Bornvl Acetate pretreated mice followed by LPS administration, the ratio of CD4+/CD8+ dropped to 0.562 ± 0.021, lower than that of LPS-abortion group (P < .01). The mean value of IFN-γ/IL-4 in LPS-treated mice was 0.310 ± 0.066, higher than that of Quercetin and Bornyl Acetate group. The results indicate that Quercetin and Bornyl Acetate have an antiabortive effect through modulation of immunological balance at maternal-fetal interface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981318"}
{"pmid": "20981317", "title": "Suppression of ongoing experimental arthritis by a chinese herbal formula (huo-luo-xiao-ling dan) involves changes in antigen-induced immunological and biochemical mediators of inflammation.", "content": "Suppression of ongoing experimental arthritis by a chinese herbal formula (huo-luo-xiao-ling dan) involves changes in antigen-induced immunological and biochemical mediators of inflammation. Rheumatoid arthritis (RA) is one of the major autoimmune diseases of global prevalence. The use of the anti-inflammatory drugs for the treatment of RA is associated with severe adverse reactions and toxicity. This limitation has necessitated the search for novel therapeutic products. We report here a traditional Chinese medicine-based herbal formula, Huo luo xiao ling dan (HLXL), which has potent antiarthritic activity as validated in the rat adjuvant-induced arthritis (AA) model. HLXL (2.3 g/Kg) was fed to Lewis (RT.1(1)) rats daily by gavage beginning at the onset of arthritis and then continued through the observation period. HLXL inhibited the severity of ongoing AA. This suppression of arthritis was associated with significant alterations in the T cell proliferative and cytokine responses as well as the antibody response against the disease-related antigen, mycobacterial heat-shock protein 65 (Bhsp65). There was a reduction in the level of the proinflammatory cytokines IL-17 and IL-1β but enhancement of the anti-inflammatory cytokine IL-10 level. In addition, there was inhibition of both the anti-Bhsp65 antibody response and the serum level of nitric oxide. Thus, HLXL is a promising CAM modality for further testing in RA patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981317"}
{"pmid": "20981320", "title": "Hypoglycemic and Hepatoprotective Activity of Fermented Fruit Juice of Morinda citrifolia (Noni) in Diabetic Rats.", "content": "Hypoglycemic and Hepatoprotective Activity of Fermented Fruit Juice of Morinda citrifolia (Noni) in Diabetic Rats. Morinda citrifolia is a medicinal plant used to treat diabetes and liver diseases. The fermented fruit juice of the M. Citrifolia (optical density = 1.25) was used to study the hypoglycemic and hepatoprotective properties in diabetes-induced rats. The rats were randomly distributed into 4 groups (control, diabetic experimental, diabetic standard, and diabetic untreated) of 6 each. Diabetes was induced by administering Streptozotocin (50 mg/kg body weight). Fasting blood glucose, body mass, liver tissue glycogen content, and the extent of liver degeneration were assessed. Diabetic experimental animals were treated with M. citrifolia juice (2 ml/kg, twice a day) and diabetic standard with reference hypoglycemic drug, glibenclamide orally for 20 days. Both the groups exhibited a significant reduction in blood glucose level of 150 mg/dl ±15.88 and 125 mg/dl ±3.89, respectively, as compared to diabetic untreated with FBS = 360.0 mg/dl ±15.81, (P < .003). On 10th day of experiment, diabetic experimental animals exhibited a decrease in body mass (10.2 g, 5.11%) which increased significantly by the 20th day (6 g, 3.0%, P < .022). Histological study of liver tissue obtained from untreated diabetic animals revealed significant fatty degeneration as compared to other three groups. The data of this study proved the hypoglycemic and hepatoprotective activity of M. citrifolia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981320"}
{"pmid": "20981319", "title": "Use of homeopathy in pediatric oncology in Germany.", "content": "Use of homeopathy in pediatric oncology in Germany. Homeopathy is a frequently used complementary and alternative medicine (CAM) treatment. We present results comparing responses of homeopathy users (HUs) and users of other forms of CAM (NHUs) in pediatric oncology (PO) in Germany. Differences between these two groups (usage, associated demographic characteristics, previous experience with CAM) are investigated. 186 (45.2%) of the 367 CAM users were exposed to homeopathy. The treatment duration amounted to a median of 601 days for HUs and 282 days for NHUs. Parents with p (127; 76.5%) also used homeopathy for their child's cancer. Nonmedical practitioners played a considerably greater role as source of information than did treating physician. In the majority HUs received their prescriptions from nonmedical practitioners (56%; 29.4% of NHUs). HUs communicate more frequently with their physicians about the CAM-use (77.7% versus 65.2%) and recommend CAM more often than NHUs (94% versus 85.6%). Homeopathy is the most frequently used CAM treatment in PO in Germany. HUs sustain treatment and therapies considerably longer than NHUs. Most families who had used homeopathy before their child was diagnosed with cancer also used homeopathy for the treatment of their child's cancer. Compared to other CAM treatments, patient satisfaction with homeopathy appears to be very high.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981319"}
{"pmid": "20981321", "title": "Retrosternal percutaneous tracheostomy: an approach for predictably impossible classic tracheostomy.", "content": "Retrosternal percutaneous tracheostomy: an approach for predictably impossible classic tracheostomy. Percutaneous tracheostomy is a routine procedure in intensive care units. In cases of very low position of the larynx, cervical spine deformation, morbid obesity, or neck tumor, performance of the classic tracheostomy is inapplicable. Retrosternal approach to tracheostomy in such 20 patients is herein reported. After preoperative neck computerized tomography to define the neck anatomy, a small suprasternal incision followed by a short retrosternal tissue dissection to expose the trachea was done; the trachea was then catheterized at the level of the 2nd ring in the usual tracheostomy manner. The immediate and late (≥6 months) outcomes were similar to that of the standard tracheostomy. Thus, percutaneous retrosternal tracheostomy is safe in patients with abnormal positioning of the trachea or neck constitution. It is a bedside applicable technique, that, however, requires caution to avoid hazardous vascular complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981321"}
{"pmid": "20981324", "title": "Leptospirosis: An Unusual Cause of ARDS.", "content": "Leptospirosis: An Unusual Cause of ARDS. Severe leptospirosis usually associates shock, jaundice, renal failure, and thrombocytopenia. Massive hemoptysis due to diffuse alveolar haemorrhage may rarely occur leading to an acute respiratory failure and multiple organ failure. We present the case of an acute respiratory distress syndrome caused by a severe leptospirosis. The severity of the respiratory failure contrasted with the absence of significant liver or renal dysfunction. Bedside open lung biopsy was only consistent with a postinfectious BOOP. The diagnosis was retrospective when the niece of the patient presented with similar inaugural symptoms ten days later after being scratched by a wild rat which was considered by our patient as a pet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981324"}
{"pmid": "20981322", "title": "Antidiabetic Potentiality of the Aqueous-Methanolic Extract of Seed of Swietenia mahagoni (L.) Jacq. in Streptozotocin-Induced Diabetic Male Albino Rat: A Correlative and Evidence-Based Approach with Antioxidative and Antihyperlipidemic Activities.", "content": "Antidiabetic Potentiality of the Aqueous-Methanolic Extract of Seed of Swietenia mahagoni (L.) Jacq. in Streptozotocin-Induced Diabetic Male Albino Rat: A Correlative and Evidence-Based Approach with Antioxidative and Antihyperlipidemic Activities. Antidiabetic, antioxidative, and antihyperlipidemic activities of aqueous-methanolic (2 : 3) extract of Swietenia mahagoni (L.) Jacq. (family Meliaceae) seed studied in streptozotocin-induced diabetic rats. Feeding with seed extract (25 mg 0.25 mL distilled water(-1)100 gm b.w.(-1)rat(-1) day(-1)) for 21 days to diabetic rat lowered the blood glucose level as well as the glycogen level in liver. Moreover, activities of antioxidant enzymes like catalase, peroxidase, and levels of the products of free radicals like conjugated diene and thiobarbituric acid reactive substances in liver, kidney, and skeletal muscles were corrected towards the control after this extract treatment in this model. Furthermore, the seed extract corrected the levels of serum urea, uric acid, creatinine, cholesterol, triglyceride, and lipoproteins towards the control level in this experimental diabetic model. The results indicated the potentiality of the extract of S. mahagoni seed for the correction of diabetes and its related complications like oxidative stress and hyperlipidemia. The extract may be a good candidate for developing a safety, tolerable, and promising neutraceutical treatment for the management of diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981322"}
{"pmid": "20981323", "title": "Gene Expression and Serum Cytokine Profiling of Low Stage CLL Identify WNT/PCP, Flt-3L/Flt-3 and CXCL9/CXCR3 as Regulators of Cell Proliferation, Survival and Migration.", "content": "Gene Expression and Serum Cytokine Profiling of Low Stage CLL Identify WNT/PCP, Flt-3L/Flt-3 and CXCL9/CXCR3 as Regulators of Cell Proliferation, Survival and Migration. Gene expression profiling (GEP) of 8 stage 0/I untreated Chronic Lymphocytic Leukemia (CLL) patients showed over-expression of Frizzled 3 (FZD3)/ROR-1 receptor tyrosine kinase (RTK), FLT-3 RTK and CXCR3 G-protein coupled receptor (GPCR). RT-PCR of 24 genes in 21 patients of the WNT pathway corroborated the GEP. Transforming growth factorβ, fibromodulin, TGFβRIII and SMAD2 are also over-expressed by GEP. Serum cytokine profiling of 26 low stage patients showed elevation of IFNγ, CSF3, Flt-3L and insulin-like growth factor binding protein 4. In order to ascertain why CLL cells grow poorly in culture, a GEP of 4 CLL patients cells at 0 hr and 24 hr in culture demonstrated over expression of CXCL5, CCL2 and CXCL3, that may recruit immune cells for survival. Treatment with thalidomide, an immunomodulatory agent, showed elevation of CCL5 by GEP but was not cytotoxic to CLL cells. Our data suggest an interplay of several oncogenic pathways, cytokines and immune cells that promote a survival program in CLL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981323"}
{"pmid": "20981326", "title": "Epidemiology, prognosis, and evolution of management of septic shock in a French intensive care unit: a five years survey.", "content": "Epidemiology, prognosis, and evolution of management of septic shock in a French intensive care unit: a five years survey. Purpose. To evaluate the epidemiology, prognosis, and management of septic shock patients hospitalized in our intensive care unit (ICU). Materiel and Methods. Five-year monocenter observational study including 320 patients. Results. ICU mortality was 54.4%. Independent mortality risk factors were mechanical ventilation (OR = 4.97), Simplify Acute Physiology Score (SAPS) II > 60 (OR = 4.28), chronic alcoholism (OR = 3.38), age >65 years (OR = 2.65), prothrombin ratio <40% (OR = 2.37), and PaO(2)/FiO(2) ratio <150 (OR = 1.91). These six mortality risk factors recovered allow screening immediately septic shock patients with a high mortality risk. Morbidity improved with time (diminution of septic shock complications, increase of the number of days alive free from mechanical ventilation and vasopressors on day 28), concomitant to an evolution of the management (earlier institution of all replacement and medical therapies and more initial volume expansion). There was no difference in mortality. Conclusion. Our study confirms a high mortality rate in septic shock patients despite a new approach of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981326"}
{"pmid": "20981325", "title": "Inhibitory Effects of Terminalia catappa on UVB-Induced Photodamage in Fibroblast Cell Line.", "content": "Inhibitory Effects of Terminalia catappa on UVB-Induced Photodamage in Fibroblast Cell Line. This study investigated whether Terminalia catappa L. hydrophilic extract (TCLW) prevents photoaging in human dermal fibroblasts after exposure to UVB radiation. TCLW exhibited DPPH free radical scavenging activity and protected erythrocytes against AAPH-induced hemolysis. In the gelatin digestion assay, the rates of collagenase inhibition by TCL methanol extract, TCLW, and its hydrolysates were greater than 100% at the concentration of 1 mg/mL. We found that serial dilutions of TCLW (10-500 μg/mL) inhibited collagenase activity in a dose-dependent manner (82.3% to 101.0%). However, TCLW did not significantly inhibit elastase activity. In addition, TCLW inhibited MMP-1 and MMP-9 protein expression at a concentration of 25 μg/mL and inhibited MMP-3 protein expression at a concentration of 50 μg/mL. TCLW also promoted the protein expression of type I procollagen. We also found that TCLW attenuated the expression of MMP-1, -3, and -9 by inhibiting the phosphorylation of ERK, JNK, and p38. These findings suggest that TCLW increases the production of type I procollagen by inhibiting the activity of MMP-1, -3 and -9, and, therefore, has potential use in anti-aging cosmetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981325"}
{"pmid": "20981327", "title": "Advent of a Link between Ayurveda and Modern Health Science: The Proceedings of the First International Congress on Ayurveda, \"Ayurveda: The Meaning of Life-Awareness, Environment, and Health\" March 21-22, 2009, Milan, Italy.", "content": "Advent of a Link between Ayurveda and Modern Health Science: The Proceedings of the First International Congress on Ayurveda, \"Ayurveda: The Meaning of Life-Awareness, Environment, and Health\" March 21-22, 2009, Milan, Italy. The First International Congress on Ayurveda was held in Milan, Italy in March 2009 and it has been the first scientific event of this kind in western world. This groundbreaking international congress was devoted to human being as the product of interactions between Awareness, Environment and Health, subjects that the West tends to consider separate and independent, but that are believed deeply connected in Ayurveda, whose interdependence defines \"The Meaning of Life\". The Congress established a bridge between indian and western philosophy, scientific and biomedical thinking in order to expand knowledge and healthcare. Main attention and address of the invited speakers was on the concept of \"relationships\" that, connecting living beings with environment, shape Nature itself. This concept is central in Ayurveda but is also common to other western scientific disciplines such as quantum physics and epigenetics that, in the four Sessions of the Congress, were represented by eminent experts. The importance of this event was underlined by the attendance of more than 400 participants and by noteworthy institutional endorsements, that added a significative political dimension of high social impact due to the topical period for CAM acceptance and integration in Europe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981327"}
{"pmid": "20981328", "title": "Selective decontamination of the digestive tract reduces pneumonia and mortality.", "content": "Selective decontamination of the digestive tract reduces pneumonia and mortality. Selective decontamination of the digestive tract (SDD) has been subject of numerous randomized controlled trials in critically ill patients. Almost all clinical trials showed SDD to prevent pneumonia. Nevertheless, SDD has remained a controversial strategy. One reason for why clinicians remained reluctant to implement SDD into daily practice could be that mortality was reduced in only 2 trials. Another reason could be the heterogeneity of trials of SDD. Indeed, many different prophylactic antimicrobial regimes were tested, and dissimilar diagnostic criteria for pneumonia were applied amongst the trials. This heterogeneity impeded interpretation and comparison of trial results. Two other hampering factors for implementation of SDD have been concerns over the risk of antimicrobial resistance and fear for escalation of costs associated with the use of prophylactic antimicrobials. This paper describes the concept of SDD, summarizes the results of published trials of SDD in mixed medical-surgical intensive care units, and rationalizes the risk of antimicrobial resistance and rise of costs associated with this potentially life-saving preventive strategy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981328"}
{"pmid": "20981330", "title": "Bone Loss Rate May Interact with Other Risk Factors for Fractures among Elderly Women: A 15-Year Population-Based Study.", "content": "Bone Loss Rate May Interact with Other Risk Factors for Fractures among Elderly Women: A 15-Year Population-Based Study. Aim was to investigate fracture risk (FR) according to bone loss (BL) rate. A random sample of 1652 women aged 53.5 years was measured with dual X-ray absorptiometry in femoral neck in 1989 and 1994 and divided into tertiles of annual BL rate: high >0.84%, moderate 0.13%-0.84%, and low <0.13%. Low trauma energy fractures during following 10 years were recorded. There were no differences in FR between BL tertiles in Cox regression model. Factors predicting lower FR in Cox model were in high tertile: high T-score (HR 0.71; 95% CI 0.54-0.93, P = .012), no sister's fracture (HR 0.35; 0.19-0.64, P = .001), no mother's fracture (HR 0.52; 0.31-0.88, P = .015), in moderate tertile: high T-score (HR 0.69;0.53-0.91, P = .008) and good grip strength (HR 0.98; 0.97-0.99, P = .022). In low tertile there were no predictors for FR. BL predicted FR in women with mother's fracture in univariate and multivariate model (OR 2.6; 1.15-5.7, P = .021) but with sister's fracture this was observed only in multivariate model (OR 2.66; 1.09-6.7, P = .039). Accordingly, the risk factors for postmenopausal fractures, especially mother's fracture, may interact with BL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981330"}
{"pmid": "20981332", "title": "Superparamagnetic bifunctional bisphosphonates nanoparticles: a potential MRI contrast agent for osteoporosis therapy and diagnostic.", "content": "Superparamagnetic bifunctional bisphosphonates nanoparticles: a potential MRI contrast agent for osteoporosis therapy and diagnostic. A bone targeting nanosystem is reported here which combined magnetic contrast agent for Magnetic Resonance Imaging (MRI) and a therapeutic agent (bisphosphonates) into one drug delivery system. This new targeting nanoplatform consists of superparamagnetic γFe(2)O(3) nanoparticles conjugated to 1,5-dihydroxy-1,5,5-tris-phosphono-pentyl-phosphonic acid (di-HMBPs) molecules with a bisphosphonate function at the outer of the nanoparticle surface for bone targeting. The as-synthesized nanoparticles were evaluated as a specific MRI contrast agent by adsorption study onto hydroxyapatite and MRI measurment. The strong adsorption of the bisphosphonates nanoparticles to hydroxyapatite and their use as MRI T2(∗) contrast agent were demonstrated. Cellular tests performed on human osteosarcoma cells (MG63) show that γFe(2)O(3)@di-HMBP hybrid nanomaterial has no citoxity effect in cell viability and may act as a diagnostic and therapeutic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981332"}
{"pmid": "20981331", "title": "Acupuncture on the Endometrial Morphology, the Serum Estradiol and Progesterone Levels, and the Expression of Endometrial Leukaemia-inhibitor Factor and Osteopontin in Rats.", "content": "Acupuncture on the Endometrial Morphology, the Serum Estradiol and Progesterone Levels, and the Expression of Endometrial Leukaemia-inhibitor Factor and Osteopontin in Rats. Although it is well known that acupuncture has beneficial effects on a variety of medical conditions especially in pain relief, nausea, and vomiting, it remains controversial whether it has positive impact on the female reproduction. The present study aimed to evaluate whether the following endometrial receptivity factors: the endometrial morphology, the hormone concentrations, and the protein expression of endometrial leukaemia-inhibitory factor (LIF) and osteopontin (OPN) could be improved by the acupuncture in clomiphene citrate(CC)-induced rat model during implantation period. Results showed that, compared with the CC group, glandular development advanced, the serum estradiol levels decreased significantly, and the glandular area and endometrial LIF and OPN expression were significantly higher in acupuncture group. There were no significant differences in serum progesterone levels, endometrial thickness, and stromal area between groups. These results suggest that acupuncture can improve certain aspects of endometrial receptivity in CC-induced rat model during implantation period, which might result in endometrial state better to female reproduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981331"}
{"pmid": "20981329", "title": "Vertebroplasty and Kyphoplasty Can Restore Normal Spine Mechanics following Osteoporotic Vertebral Fracture.", "content": "Vertebroplasty and Kyphoplasty Can Restore Normal Spine Mechanics following Osteoporotic Vertebral Fracture. Osteoporotic vertebral fractures often lead to pain and disability. They can be successfully treated, and possibly prevented, by injecting cement into the vertebral body, a procedure known as vertebroplasty. Kyphoplasty is similar, except that an inflatable balloon is used to restore vertebral body height before cement is injected. These techniques are growing rapidly in popularity, and a great deal of recent research, reviewed in this paper, has examined their ability to restore normal mechanical function to fractured vertebrae. Fracture reduces the height and stiffness of a vertebral body, causing the spine to assume a kyphotic deformity, and transferring load bearing to the neural arch. Vertebroplasty and kyphoplasty are equally able to restore vertebral stiffness, and restore load sharing towards normal values, although kyphoplasty is better at restoring vertebral body height. Future research should optimise these techniques to individual patients in order to maximise their beneficial effects, while minimising the problems of cement leakage and adjacent level fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981329"}
{"pmid": "20981334", "title": "Geographic variation in osteoporotic hip fracture incidence: the growing importance of asian influences in coming decades.", "content": "Geographic variation in osteoporotic hip fracture incidence: the growing importance of asian influences in coming decades. Studies over the last few decades have demonstrated geographic variation in the incidence of hip fracture across continents and among different parts of the same region. This paper studies the epidemiology of hip fracture worldwide, with special emphasis on the geographic variation among Asian countries. Using the Pubmed database, keywords that were employed included hip fracture, incidence rate, geographic variation, osteoporosis, and epidemiology. Articles were chosen based on the basis of (1) focus: studies that were said to specifically focus on geographic variation in hip fracture from different continents with a focus on Asia; (2) language: studies that were in English; (3) methods: studies that used statistical tests to examine hip fracture incidence rates. The highest hip fracture rates are seen in Scandinavian countries and the US and the lowest in African countries. Fracture rates are intermediate in Asian populations. Among different ethnic populations, the highest fracture rates are seen in Caucasians and the lowest in blacks. There is also a north-south gradient, particularly in Europe, where more hip fractures occur in North Europe compared to the South.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981334"}
{"pmid": "20981333", "title": "Prevalence of dietary supplement use in patients with proven or suspected cardiovascular disease.", "content": "Prevalence of dietary supplement use in patients with proven or suspected cardiovascular disease. Systematic search of bibliographic databases was conducted to describe the prevalence of dietary supplement use in cardiac patients. Included for review were studies that investigated supplement use in people with cardiovascular risk factors or proven cardiovascular disease. Databases searched were Medline, EMBASE, CINAHL, AMED, Meditext, H&S and IPA. Over five hundred articles were retrieved and twenty studies met the criteria for this review. Dietary supplements were taken by a median 36% (interquartile range: 26-42%) of cardiac patients; 36% (IQR 18-43%) reported taking a vitamin/mineral supplement and 12% (IQR 7-21%) used herbal supplements. Many users indicated that supplements were taken specifically for heart health and 16-64% of users reported using supplements alongside prescription medications. However 39-95% of treating physicians were unaware of patients' supplement use. Dietary supplement use in patients with cardiovascular disease appears common, as does the concurrent use of supplements with prescription medicines. This information is often not communicated to doctors and treating physicians may need to be more proactive in asking about supplement use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981333"}
{"pmid": "20981335", "title": "Osteoporosis-related simultaneous four joints fractures and dislocation after a seizure: a case report.", "content": "Osteoporosis-related simultaneous four joints fractures and dislocation after a seizure: a case report. A case of steroid-induced osteoporosis-related multiple fractures and dislocations are described after a seizure is reported. Patient had two years history of steroid use with no supplement or antiresorptive therapy. There was a delay in the diagnosis which affected an otherwise good outcome in such situations. It is recommended that patients on steroid should be given calcium, vitamin D, and an antiresorptive. Furthermore, a meticulous clinical examination is required in patients who are on steroids and suffer epileptic seizures to rule out skeletal injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981335"}
{"pmid": "20981337", "title": "Calcaneal BMD Obtained by Dual X-Ray and Laser Predicts Future Hip Fractures-A Prospective Study on 4 398 Swedish Women.", "content": "Calcaneal BMD Obtained by Dual X-Ray and Laser Predicts Future Hip Fractures-A Prospective Study on 4 398 Swedish Women. The predictive value of dual X-ray and laser (DXL) calcaneal BMD (BMD(DXL)) on hip fractures was prospectively studied in 4,398 females aged 55 to 99 years. The average follow-up period was 3 years and 11 months with a total of 17,270 person years. Fractures were identified from the national patient register. After inclusion, 130 females sustained a hip fracture. The age adjusted hazard ratio for T-score <-2.5 versus >-2.5 was 2.64. Of all patients who sustained a hip fracture 78% had a T-score of -2.5 or below. The annual hip fracture rate was 0.26% at T-scores ≥-2, but 1.5% at T-scores ≤-2.5. The area under curve for the model including calcaneal BMD(DXL), follow-up time, and age to prospectively predict hip fractures was 0.84. Conclusions. Calcaneal BMD(DXL) obtained by DXL Calscan predicts hip fractures and may therefore be suitable for diagnosing osteoporosis and for predicting fracture risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981337"}
{"pmid": "20981339", "title": "Is childhood obesity associated with bone density and strength in adulthood?", "content": "Is childhood obesity associated with bone density and strength in adulthood? Associations between childhood obesity and adult bone traits were assessed among 62 obese premenopausal women, of which 12 had been obese since childhood (ObC), and 50 had gained excess weight in adulthood (ObA). Body composition and bone mineral content (BMC) of the total body, spine, and proximal femur were assessed with DXA. Total cross-sectional area and cortical (diaphyseal CoD) and trabecular (epiphyseal TrD) bone density of the radius and tibia were measured with pQCT. Compared to ObA-group, ObC-group was 5.2 cm taller having 2.5 and 3.5 kg more lean and fat mass, respectively. Depending on the statistical adjustment, ObC-group had 5-10% greater TrD both in tibia and in radius. The remaining bone traits did not significantly differ between the groups. Current preliminary observations bring up an interesting question whether childhood obesity can result in denser trabecular bone in adulthood. However, prudence must be exercised in the statistical adjustment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981339"}
{"pmid": "20981340", "title": "Sclerostin.", "content": "Sclerostin. The striking clinical benefits of intermittent parathyroid hormone in osteoporosis have begun a new era of skeletal anabolic agents. One potential new agent is monoclonal antibody to sclerostin, a potent inhibitor of osteoblastogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981340"}
{"pmid": "20981338", "title": "The significance of soy protein and soy bioactive compounds in the prophylaxis and treatment of osteoporosis.", "content": "The significance of soy protein and soy bioactive compounds in the prophylaxis and treatment of osteoporosis. Osteoporosis is defined as a progressive systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Although bone mass and quality is mainly determined genetically, many other factors, including lifestyle and nutrition also have an impact on bone health. It has been suggested that dietary protein intake may be a risk factor for osteoporosis, and high-protein diets are associated with increased bone loss. Many scientists have examined the relationship between types of protein and urinary calcium excretion, and found that although animal protein was associated with increased urinary calcium excretion, soy protein was not. There is sufficient evidence suggesting soy isoflavones may have potential benefits for bone. Soy protein with naturally occurring phytoestrogens, mainly isoflavones protect against bone loss and synthetic soy ipriflavone in some studies has been shown to favorably affect, but a cause and effect relationship has not been established between the consumption of ipriflavone and maintenance of bone mineral density in post-menopausal women. Therefore it is too early to recommend it as a supplement for this group of women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981338"}
{"pmid": "20981336", "title": "Scientific basis for the potential use of melatonin in bone diseases: osteoporosis and adolescent idiopathic scoliosis.", "content": "Scientific basis for the potential use of melatonin in bone diseases: osteoporosis and adolescent idiopathic scoliosis. The objective of this paper was to analyze the data supporting the possible role of melatonin on bone metabolism and its repercussion in the etiology and treatment of bone pathologies such as the osteoporosis and the adolescent idiopathic scoliosis (AIS). Melatonin may prevent bone degradation and promote bone formation through mechanisms involving both melatonin receptor-mediated and receptor-independent actions. The three principal mechanisms of melatonin effects on bone function could be: (a) the promotion of the osteoblast differentiation and activity; (b) an increase in the osteoprotegerin expression by osteoblasts, thereby preventing the differentiation of osteoclasts; (c) scavenging of free radicals generated by osteoclast activity and responsible for bone resorption. A variety of in vitro and in vivo experimental studies, although with some controversial results, point toward a possible role of melatonin deficits in the etiology of osteoporosis and AIS and open a new field related to the possible therapeutic use of melatonin in these bone diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981336"}
{"pmid": "20981341", "title": "Ewing's Sarcoma and Second Malignancies.", "content": "Ewing's Sarcoma and Second Malignancies. Ewing's sarcoma (ES) is a rare tumor that is most common in children and young adults. Late effects of ES therapy include second cancers, a tragic outcome for survivors of such a young age. This paper will explore the frequencies and types of malignancies that occur after ES. Additionally, it will review how second malignancies have changed with the shift in treatment from high-dose radiation to chemotherapy regimens including alkylators and epipodophyllotoxins. The risk of additional cancers in ES survivors will also be compared to survivors of other childhood cancers. Finally, the possible genetic contribution to ES and second malignancies will be discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981341"}
{"pmid": "20981343", "title": "Development of a multicommutated flow system with chemiluminometric detection for quantification of gentamicin in pharmaceuticals.", "content": "Development of a multicommutated flow system with chemiluminometric detection for quantification of gentamicin in pharmaceuticals. A new flow procedure based on multicommutation with chemiluminometric detection was developed to quantify gentamicin sulphate in pharmaceutical formulations. This approach is based on gentamicin's ability to inhibit the chemiluminometric reaction between luminol and hypochlorite in alkaline medium, causing a decrease in the analytical signal. The inhibition of the analytical signal is proportional to the concentration of gentamicin sulphate, within a linear range of 1 to 4 μg mL(-1) with a coefficient variation <3%. A sample throughput of 55 samples h(-1) was obtained. The developed method is sensitive, simple, with low reagent consumption, reproducible, and inexpensive, and when applied to the analysis of pharmaceutical formulations (eye drops and injections) it gave results with RSD between 1.10 and 4.40%.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981343"}
{"pmid": "20981342", "title": "Discovery of a Novel Chemical Class of mGlu(5) Allosteric Ligands with Distinct Modes of Pharmacology.", "content": "Discovery of a Novel Chemical Class of mGlu(5) Allosteric Ligands with Distinct Modes of Pharmacology. We previously discovered a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 5 (mGlu(5)) termed 4 N-{4-chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) that elicits receptor activation through a novel allosteric site on mGlu(5), distinct from the classical mGlu(5) negative allosteric modulator (NAM) MPEP allosteric site. However, a shallow structure-activity relationship (SAR), poor physiochemical properties, and weak PAM activity at rat mGlu(5) limited the utility of CPPHA to explore allosteric activation of mGlu(5) at a non-MPEP site. Thus, we performed a functional high-throughput screen (HTS) and identified a novel mGlu(5) PAM benzamide scaffold, exemplified by VU0001850 (EC(50) = 1.3 μM, 106% Glu(max)) and VU0040237 (EC(50) = 350 nM, 84% Glu Max). An iterative parallel synthesis approach delivered 22 analogues, optimized mGlu(5) PAM activity to afford VU0357121 (EC(50) = 33 nM, 92% Glu(max)), and also revealed the first non-MPEP site neutral allosteric ligand (VU0365396). Like CPPHA, PAMs within this class do not appear to bind at the MPEP allosteric site based on radioligand binding studies. Moreover, mutagenesis studies indicate that VU0357121 and related analogues bind to a yet uncharacterized allosteric site on mGlu(5), distinct from CPPHA, yet share a functional interaction with the MPEP site.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981342"}
{"pmid": "20981344", "title": "Radiotherapy for soft tissue sarcoma of the proximal lower extremity.", "content": "Radiotherapy for soft tissue sarcoma of the proximal lower extremity. Soft-tissue sarcoma (STS) is a histopathologically diverse group of tumors accounting for approximately 10,000 new malignancies in the US each year. The proximal lower extremity is the most common site for STS, accounting for approximately one-third of all cases. Coordinated multimodality management in the form of surgery and radiation is often critical to local control, limb preservation, and functional outcome. Based on a review of currently available Medline literature and professional experience, this paper provides an overview of the treatment of STS of the lower extremity with a particular focus on the modern role of radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981344"}
{"pmid": "20981345", "title": "Airbag pneumonitis.", "content": "Airbag pneumonitis. The widespread and mandatory use of airbags has resulted in various patterns of injuries and complications unique to their use. Airbags have been implicated in a spectrum of pulmonary conditions ranging from exacerbation of asthma, reactive airway diseases to new onset asthma. We report a case of inhalational chemical pneumonitis that developed after exposure to the airbag fumes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981345"}
{"pmid": "20981346", "title": "Forebrain ischemia triggers GABAergic system degeneration in substantia nigra at chronic stages in rats.", "content": "Forebrain ischemia triggers GABAergic system degeneration in substantia nigra at chronic stages in rats. The long-term consequences of forebrain ischemia include delayed Parkinson's syndrome. This study revealed delayed neurodegeneration in the substantia nigra 8 weeks after 12.5 minutes of global ischemia in rat brain. Following neuronal loss of 30-40% in central and dorsolateral striatum at day 3, neuronal damage in the substantia nigra (SN) was assessed at 4-8 weeks using immunohistochemistry for glutamate decarboxylase 67 (GAD67), vesicular GABA transporter (VGAT), and calretinin (CR). At day 56, the optical density of GAD67-, but not VGAT-, immunoreactivity in substantia nigra pars reticulata (SNR)-significantly decreased. CR-neurons concentrated in substantia nigra pars compacta (SNC) were reduced by 27% from day 3 (n = 5) to day 56 (n = 7, ANOVA, p < .01). Movement coordination was impaired at day 56, as evaluated using beam-walking test (time-to-traverse 5.6 ± 1.2 sec versus 11.8 ± 5.4 sec; sham versus ischemia, p < .05, n = 5, and 7, resp.). Our results demonstrate delayed impairment of the GABAergic system components in SN and associated with movement deficits after global ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981346"}
{"pmid": "20981348", "title": "Anaesthesia for emergency caesarean section in a patient with large anterior mediastinal tumour presenting as intrathoracic airway compression and superior vena cava obstruction.", "content": "Anaesthesia for emergency caesarean section in a patient with large anterior mediastinal tumour presenting as intrathoracic airway compression and superior vena cava obstruction. Anterior mediastinal mass is an uncommon pathology that presents significant anaesthetic challenges because of cardiopulmonary compromise. We present a case that presented in the third trimester of pregnancy with severe breathlessness, orthopnoea, and symptoms of superior vena cava obstruction. The patient had emergency Caesarean section under epidural anaesthesia with a good outcome. The paper discusses the relevant perioperative considerations for this complex scenario and reviews reports of similar conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981348"}
{"pmid": "20981347", "title": "Pathobiologic markers of the ewing sarcoma family of tumors: state of the art and prediction of behaviour.", "content": "Pathobiologic markers of the ewing sarcoma family of tumors: state of the art and prediction of behaviour. Over the past three decades, the outcome of Ewing sarcoma family tumor (ESFT) patients who are nonmetastatic at presentation has improved considerably. The prognosis of patients with metastatic disease at the time of diagnosis and recurrence after therapy remains dismal. Drug-resistant disease at diagnosis or at relapse remains a major cause of mortality among patients diagnosed with ESFT. In order to improve the outcome for patients with potential relapse, there is an urgent need to find reliable markers that either predict tumor behaviour at diagnosis or identify therapeutic molecular targets at the time of recurrence. An improved understanding of the cell of origin and the molecular pathways that regulate tumorigenicity in ESFT should aid us in the search for novel therapies for ESFT. The purpose of this paper is thus to outline current concepts of sarcomagenesis in ESFT and to discuss ESFT patterns of differentiation and molecular markers that might affect prognosis or direct future therapeutic development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981347"}
{"pmid": "20981349", "title": "Porcine cysticercosis and risk factors in the gambia and senegal.", "content": "Porcine cysticercosis and risk factors in the gambia and senegal. During a stratified cross-sectional survey, 1705 pigs were sampled from 279 randomly selected households, 63 randomly selected communities and villages, from four study areas in The Gambia and Senegal during the period October 2007 to January 2008. Porcine cysticercosis prevalence detected by tongue inspection at animal level per study area ranged from 0.1% to 1.0%. Using an antigen-detection ELISA the seroprevalence of cysticercosis at both community/village and animal levels for the four selected study areas is: Western region 80.0% (95%CI: 52.4%-93.6%) and 4.8% (95%CI: 3.4%-6.5%), Bignona 86.7% (95%CI: 59.8%-96.6%) and 8.9% (95%CI: 5.0%-15.5%), Kolda 82.4% (95%CI: 46.8%-96.1%) and 13.2% (95%CI: 10.8%-16.0%), and Ziguinchor 81.3% (95%CI: 43.5%-96.1%) and 6.4% (95%CI: 4.0%-10.1%), respectively. No risk factors for cysticercosis were found significant in this study. This study proved that porcine cysticercosis is endemic and distributed widely in the study areas though its incidence might be suppressed by the generalised use of toilets and latrines in the study areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981349"}
{"pmid": "20981351", "title": "Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study.", "content": "Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study. We performed a prospective study to examine the genetic effect on the response to a calcium (Ca) channel blocker, azelnidipine and an ACE inhibitor, temocapril treatment in patients with hypertension, as a part of the prior clinical trial, the Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study (ATTEST). Methods and Results. All subjects who gave informed consent for genetic research were divided into two groups: the subjects treated with azelnidipine or temocapril, for 52 weeks. We selected 18 susceptible genes for hypertension and determined their genotypes using TaqMan PCR method. RNA samples were extracted from peripheral blood, and quantitative real time PCR for all genes was performed using TaqMan method. One of the polymorphisms of the RGS2 gene was extracted as being able to influence the effect of these treatments to reduce BP. At eight weeks, BP change showed a significant interaction between the A-638G polymorphism of Regulator of G protein signaling-2 (RGS2) gene and treatment with azelnidipine or temocapril. There was no gene whose expression was associated with BP phenotypes or the polymorphisms of each gene. Conclusions. A-638G polymorphism of the RGS-2 gene could be a predictive factor for therapeutic performance of Ca channel blockers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981351"}
{"pmid": "20981350", "title": "Lung cancer risk and genetic polymorphisms in DNA repair pathways: a meta-analysis.", "content": "Lung cancer risk and genetic polymorphisms in DNA repair pathways: a meta-analysis. Genetic variations in DNA repair genes are thought to modulate DNA repair capacity and are suggested to be related to lung cancer risk. We conducted a meta-analysis of epidemiologic studies on the association between genetic polymorphisms in both base excision repair and nucleotide excision repair pathways, and lung cancer. We found xeroderma pigmentosum complementation group A (XPA) G23A (odds ratio (OR) = 0.76, 95% confidence interval (CI) = 0.61-0.94), 8-oxoguanine DNA glycosylase 1 (OGG1) Ser326Cys (OR = 1.22, 95% CI = 1.02-1.45), and excision repair cross-complementing group 2 (ERCC2) Lys751Gln (OR = 1.27, 95% CI = 1.10-1.46) polymorphisms were associated with lung cancer risk. Considering the data available, it can be conjectured that if there is any risk association between a single SNP and lung cancer, the risk fluctuation will probably be minimal. Advances in the identification of new polymorphisms and in high-throughput genotyping techniques will facilitate the analysis of multiple genes in multiple DNA repair pathways. Therefore, it is likely that the defining feature of future epidemiologic studies will be the simultaneous analysis of large samples of cases and controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981350"}
{"pmid": "20981354", "title": "Maxillofacial materials reinforced with various concentrations of polyhedral silsesquioxanes.", "content": "Maxillofacial materials reinforced with various concentrations of polyhedral silsesquioxanes. This study evaluates two mechanical properties, tensile strength and tear strength, of maxillofacial materials reinforced with functional polyhedral silsesquioxane (POSS) nanoparticles at 0.0, 0.5, 1.0, 2.0, and 5.0% (mass/mass) loading. Adding POSS was found to significantly affect the overall tensile strength and extensibility of the maxillofacial material. Significant differences were found in mean peak load (p = .050) and extension before failure (p = .050), respectively, between concentrations of 0% and 5%. For tear resistance, a significant difference was observed in mean load (p = .002) between concentrations of 1% and 5%. Significant differences were also observed in extension before failure between concentrations of 0% and 1% (p = .002) and between 0% and 2% (p = .002). Increased resistance to tensile or shearing stresses could lead to greater clinical longevity. The following results suggest that functional nanoparticles can be used to improve properties without compromising clinical handling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981354"}
{"pmid": "20981353", "title": "Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice.", "content": "Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. Mice transgenic for production of excessive or mutant forms of beta-amyloid differ from patients with Alzheimer's disease in the degree of inflammation, oxidative damage, and alteration of intermediary metabolism, as well as the paucity or absence of neuronal atrophy and cognitive impairment. Previous observers have suggested that differences in inflammatory response reflect a discrepancy in the state of the locus coeruleus (LC), loss of which is an early change in Alzheimer's disease but which is preserved in the transgenic mice. In this paper, we extend these observations by examining the effects of the LC on markers of oxidative stress and intermediary metabolism. We compare four groups: wild-type or Tg2576 Aβ transgenic mice injected with DSP4 or vehicle. Of greatest interest were metabolites different between ablated and intact transgenics, but not between ablated and intact wild-type animals. The Tg2576_DSP4 mice were distinguished from the other three groups by oxidative stress and altered energy metabolism. These observations provide further support for the hypothesis that Tg2576 Aβ transgenic mice with this ablation may be a more congruent model of Alzheimer's disease than are transgenics with an intact LC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981353"}
{"pmid": "20981352", "title": "Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis.", "content": "Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis. Despite advances in treatment, cancer remains the 2nd most common cause of death in the United States. Poor cure rates may result from the ability of cancer to recur and spread after initial therapies have seemingly eliminated detectable signs of disease. A growing body of evidence supports a role for cancer stem cells (CSCs) in tumor regrowth and spread after initial treatment. Thus, targeting CSCs in combination with traditional induction therapies may improve treatment outcomes and survival rates. Unfortunately, CSCs tend to be resistant to chemo- and radiation therapy, and a better understanding of the mechanisms underlying CSC resistance to treatment is necessary. This paper provides an update on evidence that supports a fundamental role for CSCs in cancer progression, summarizes potential mechanisms of CSC resistance to treatment, and discusses classes of drugs currently in preclinical or clinical testing that show promise at targeting CSCs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981352"}
{"pmid": "20981355", "title": "Genome-wide association studies of hypertension: light at the end of the tunnel.", "content": "Genome-wide association studies of hypertension: light at the end of the tunnel. Despite its significant genetic component, the study of hypertension by genome-wide association presents more challenges than other common complex diseases. Its high prevalence, heterogeneity, and somewhat unclear definition are the challenges that need to be overcome on one hand. On the other hand, there are issues of small effect sizes and pleiotropism that are not specific to hypertension alone but nonetheless magnify the problems of genetic dissection when coupled with phenotypic misclassification. We discuss issues of study design and summarise published genome-wide association studies (GWASs) of hypertension and blood pressure. With careful study design and analysis success is possible, as demonstrated by the recent large-scale studies. Following these, there is still further scope to advance the field through high fidelity phenotyping and deep sequencing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981355"}
{"pmid": "20981356", "title": "Quasi-static and harmonic indentation of osteonal bone.", "content": "Quasi-static and harmonic indentation of osteonal bone. The purpose of the study was to compare Quasi-Static (QS) and harmonic (CSM) methods of indentation testing. Bone sections were obtained from mid-femoral diaphyses of dogs which received a pair of calcein labels. Labeled (n = 35) and unlabeled (n = 112) osteons were identified. Indentation modulus (IM) and hardness (H) for the CSM method were collected during the entire loading cycle to peak depth, while IM and H for QS method were calculated at a peak depth of 500 nm. The mean (SD) of the IM and H for labeled osteons were as follows: QS IM = 15.3 GPa (3.85) versus CSM IM = 14.7 GPa (3.58); P = .52 and QS H = .39 GPa (.171) versus CSM H = .42 GPa (.146); P = .32. The mean (SD) of the IM and H for unlabeled osteons were as follows: QS IM = 21.5 GPa (2.80) versus CSM IM = 20.6 GPa (2.53); P = .054 and QS H = .64 GPa (.117) versus CSM H = .70 GPa (.120); P = .017. There was no difference in IM and H for the two methods, except for H of the unlabeled osteons. In addition, for the CSM method, IM at 100 nm, 200 nm, 300 nm, 400 nm and 500 nm were not statistically significant different (P = .06). Bone is viscoelastic at an organ level. However, this component of its behavior was not detected at the length scale examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981356"}
{"pmid": "20981359", "title": "Development of the first well-defined tungsten oxo alkyl derivatives supported on silica by SOMC: towards a model of WO3/SiO2 olefin metathesis catalyst.", "content": "Development of the first well-defined tungsten oxo alkyl derivatives supported on silica by SOMC: towards a model of WO3/SiO2 olefin metathesis catalyst. A well-defined, silica-supported tungsten oxo alkyl species prepared by the surface organometallic chemistry approach displays high and sustained activity in propene metathesis. Remarkably, its catalytic performances outpace those of the parent imido derivative, underlining the importance of the oxo ligand in the design of robust catalysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981359"}
{"pmid": "20981358", "title": "Expression of O-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients.", "content": "Expression of O-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients. Bladder tumour tissues and corresponding uninvolved mucosa (normal tissue) of Egyptian bladder cancer patients were assessed for O(6)-alkylguanine-DNA-alkyltransferase (MGMT) activity by functional assay of tissue extracts (36 paired samples), and distribution by immunofluorescence (IF) microscopy of fixed material (24 paired samples). MGMT varied widely from 42-253 fmoles/mg protein and from 3.2-40 fmoles/μg DNA in normal and 58-468 fmoles/mg protein and 2.5-49.5 fmoles/mg protein, in the tumour tissues; only one tumour had undetectable activity. Pairwise comparison of MGMT activity in tumour and adjacent normal tissue showed no significant difference based on DNA content but was 1.75-fold higher in tumour (P < .01) based on protein. There was no effect of gender or bilharzia infection status. IF showed that in tumours, both the mean percentage of positive nuclei (57.3 ± 20.3%) and mean integrated IF (5.47 ± 3.66) were significantly higher than those in uninvolved tissues (42.8 ± 13.5% P = .04) and (1.89 ± 1.42; P < .01), respectively. These observations suggest that, overall, MGMT levels are increased during human bladder carcinogenesis and that MGMT downregulation is not a common feature of bladder cancers. Based on this, bladder cancers would be expected to be relatively resistant to chemotherapy which involved O(6)-guanine alkylating antitumour agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981358"}
{"pmid": "20981360", "title": "Single exposure fabrication and manipulation of 3D hydrogel cell microcarriers.", "content": "Single exposure fabrication and manipulation of 3D hydrogel cell microcarriers. We present a simple and high-throughput method for fabricating free-floating hydrogel cell microcarriers using single exposure UV patterning. We also demonstrate magnetic manipulation of the free-floating cell microcarriers using a magnetic nanoparticle-embedded structure for an active agitation and a solution exchange.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981360"}
{"pmid": "20981361", "title": "Probing magnetic and gold nanoparticles by using MAClevers® as ultrasensitive sensors.", "content": "Probing magnetic and gold nanoparticles by using MAClevers® as ultrasensitive sensors. Magnetic AFM probes known as MAClevers® were employed for sensing picogram amounts of magnetic nanoparticles, based on the cantilever frequency shifts resulting from the magnetically induced adsorption of mass. By using organothiol functionalized magnetic nanoparticles, this analytical strategy was successfully extended to the detection of gold nanoparticles, as confirmed by confocal Raman microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981361"}
{"pmid": "20981362", "title": "Transition metal induced magnetism in smaller fullerenes (Cn for n≤36).", "content": "Transition metal induced magnetism in smaller fullerenes (Cn for n≤36). The magnetic properties of 3d transition metals (TM) encapsulated inside smaller fullerenes ranging from C20 to C36 have been investigated using spin polarized density functional theory. The TM impurities stabilize asymmetrically at an off-center position for n≥28. The total magnetic moment (MM) of TM@Cn complexes are largely contributed by TMs and a small amount of MM of 0.12-0.50 μB is induced on the cage carbon atoms. The 3d TM atoms interact with C atoms of C20 and C28 cage ferromagnetically (FM) except for Ni@C28 which shows antiferromagnetic (AFM) interaction. The magnetic interactions change from FM to AFM in C32 cage for Ti, V, Cr and Mn. The MM gets quenched in Ni@Cn for n≥32. The total MM of Mn@Cn does not show any change although the nature of magnetic interactions changes from FM to AFM at n=32. Ti and V are the only TMs which show positive cohesive energy in all fullerenes considered. The smallest fullerene which can encapsulate all 3d TM are Cn for n≥32, consistent with available experimental and theoretical results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981362"}
{"pmid": "20981363", "title": "Photofragmentation in selected tautomers of protonated adenine.", "content": "Photofragmentation in selected tautomers of protonated adenine. The photofragmentation by UV excitation of selectively prepared 1(+) and 3(+) tautomers of protonated adenine is studied after excitation at a 266 and 263 nm wavelengths with two different experimental set-ups located in Seoul and Orsay. While the production of 1(+) tautomers with an electrospray ion source is now well accepted, calculations were used to ascribe the preparation of 3(+) tautomers from cold adenine dimers. The fragmentation patterns are rather similar for both tautomers, suggesting similar mechanisms as a statistical fragmentation in the ground electronic state after internal conversion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981363"}
{"pmid": "20981365", "title": "SR-FTIR spectroscopy of renal epithelial carcinoma side population cells displaying stem cell-like characteristics.", "content": "SR-FTIR spectroscopy of renal epithelial carcinoma side population cells displaying stem cell-like characteristics. It is hypothesized that cells with stem cell-like properties may be influential in carcinogenesis, possessing the ability to self-renew, produce differentiated daughter cells and resist environmental or therapeutic injury. This has led to a surge in interest in identifying and characterizing the tumour initiating or cancer stem cell (CSC) with the aim of discovering novel diagnostic and prognostic markers and of understanding the basic biology with the ultimate aim of generating new therapeutic approaches and biomarkers. However, a major hurdle to this process has been the lack of a truly specific cancer stem cell biomarker allied to the rarity of these cells. This has led to problems in characterising these CSCs by traditional '-omic' techniques. Using a renal carcinoma cell line model, we show that synchrotron radiation-Fourier transform infrared (SR-FTIR) spectroscopy is a suitable tool to measure discrete differences in the biochemistry of small numbers of single-cells. Using the chemometric techniques of Principal Component and Linear Discriminant Analysis (PCA and LDA) for multivariate reduction, biochemical differences between the cells from different sub-populations were evaluated. Results found lipid and phosphodiester vibrations to be particularly good discriminating markers in the spectra of these stem-like cells, relative to the more differentiated, proliferating cells that make up the majority of the cell population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981365"}
{"pmid": "20981364", "title": "A microfluidic approach for investigating the temperature dependence of biomolecular activity with single-molecule resolution.", "content": "A microfluidic approach for investigating the temperature dependence of biomolecular activity with single-molecule resolution. We present a microfluidic approach for single-molecule studies of the temperature-dependent behavior of biomolecules, using a platform that combines microfluidic sample handling, on-chip temperature control, and total internal reflection fluorescence (TIRF) microscopy of surface-immobilized biomolecules. With efficient, rapid, and uniform heating by microheaters and in situ temperature measurements within a microfluidic flowcell by micro temperature sensors, closed-loop, accurate temperature control is achieved. To demonstrate its utility, the temperature-controlled microfluidic flowcell is coupled to a prism-based TIRF microscope and is used to investigate the temperature-dependence of ribosome and transfer RNA (tRNA) structural dynamics that are required for the rapid and precise translocation of tRNAs through the ribosome during protein synthesis. Our studies reveal that the previously characterized, thermally activated transitions between two global conformational states of the pre-translocation (PRE) ribosomal complex persist at physiological temperature. In addition, the temperature-dependence of the rates of transition between these two global conformational states of the PRE complex reveal well-defined, measurable, and disproportionate effects, providing a robust experimental framework for investigating the thermodynamic activation parameters that underlie transitions across these barriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981364"}
{"pmid": "20981367", "title": "Enantioselective synthesis of spirooxoindoles via chiral auxiliary (bicyclic lactam) controlled SNAr reactions.", "content": "Enantioselective synthesis of spirooxoindoles via chiral auxiliary (bicyclic lactam) controlled SNAr reactions. A highly efficient enantioselective S(N)Ar reaction of chiral acyl bicyclic lactam with substituted-2,4-dinitrobenzenes was developed, affording products containing quarternary stereogenic centers. They are further utilized towards an enantioselective synthesis of spirooxoindoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981367"}
{"pmid": "20981366", "title": "Nucleotidylation of unsaturated carbasugar in validamycin biosynthesis.", "content": "Nucleotidylation of unsaturated carbasugar in validamycin biosynthesis. Validamycin A is a member of microbial-derived C(7)N-aminocyclitol family of natural products that is widely used as crop protectant and the precursor of the antidiabetic drug voglibose. Its biosynthetic gene clusters have been identified in several Streptomyces hygroscopicus strains, and a number of genes within the clusters have been functionally analyzed. Of these genes, valB, which encodes a sugar nucleotidyltransferase, was found through inactivation study to be essential for validamycin biosynthesis, but its role was unclear. To characterize the role of ValB in validamycin biosynthesis, four carbasugar phosphate analogues were synthesized and tested as substrate for ValB. The results showed that ValB efficiently catalyzes the conversion of valienol 1-phosphate to its nucleotidyl diphosphate derivatives, whereas other unsaturated carbasugar phosphates were found to be not the preferred substrate. ValB requires Mg(2+), Mn(2+), or Co(2+) for its optimal activity and uses the purine-based nucleotidyltriphosphates (ATP and GTP) more efficiently than the pyrimidine-based NTPs (CTP, dTTP, and UTP) as nucleotidyl donor. ValB represents the first member of unsaturated carbasugar nucleotidyltransferases involved in natural products biosynthesis. Its characterization not only expands our understanding of aminocyclitol-derived natural products biosynthesis, but may also facilitate the development of new tools for chemoenzymatic synthesis of carbohydrate mimetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981366"}
{"pmid": "20981368", "title": "Reversible phase transfer and fractionation of Au nanoparticles by pH change.", "content": "Reversible phase transfer and fractionation of Au nanoparticles by pH change. The reversible transfer of Au nanoparticles between water and chloroform phases by pH change was achieved by using a long-chain amine derivative. Further, we demonstrated that the phase transfer method was very effective for the fractionation of Au nanoparticles according to their crystal facet distinction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981368"}
{"pmid": "20981373", "title": "Chiral separation and determination of ofloxacin enantiomers by ionic liquid-assisted ligand-exchange chromatography.", "content": "Chiral separation and determination of ofloxacin enantiomers by ionic liquid-assisted ligand-exchange chromatography. A simple and accurate method for the separation and determination of ofloxacin enantiomers was developed by ionic liquid-assisted ligand-exchange high performance liquid chromatography. Both achiral and chiral ionic liquids were tested for their efficiency of ofloxacin enantiomeric separation. The effects of ligands, concentration of metal ion, organic modifier, pH of the mobile phase, and temperature were also investigated and evaluated. Optimal conditions were obtained on a conventional C(18) column, where the mobile phase consisted of methanol/water (20 : 80, v/v) (containing 4.0 mmol L(-1) amino acid ionic liquid and 3.0 mmol L(-1) copper sulfate) at a flow rate of 0.5 mL min(-1). Under this condition, the ofloxacin enantiomers could be baseline separated within 14 minutes; the proposed method was used to analyze different commercial ofloxacin medicines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981373"}
{"pmid": "20981374", "title": "SAXS in combination with a free liquid jet for improved time-resolved in situ studies of the nucleation and growth of nanoparticles.", "content": "SAXS in combination with a free liquid jet for improved time-resolved in situ studies of the nucleation and growth of nanoparticles. A new setup for fast in situ SAXS studies of early stages in the nucleation and growth of colloidal nanoparticles is presented. Evading the disturbing influence of container walls and minimizing the possibility of beam-induced reactions, the benefits of the setup are demonstrated exemplarily for the well-known synthesis of gold nanoparticles via the Turkevich method. Analysis with the new experimental setup reveals the initial rate of particle formation, and enables analysis of particle growth rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981374"}
{"pmid": "20981375", "title": "Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates.", "content": "Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates. Tri-functional activity-based protein probes that encompass an electrophilic trap, a photo-reactive group and a bio-orthogonal ligation handle are described. With these, and in a three-step chemical proteomics approach, proteasomal catalytic sites are covalently and irreversibly modified, followed by photocrosslinking of these to flanking subunits and Staudinger-Bertozzi ligation for visualization and identification of the resulting conjugates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981375"}
{"pmid": "20981376", "title": "Highly sensitive naked-eye and fluorescence \"turn-on\" detection of Cu(2+) using Fenton reaction assisted signal amplification.", "content": "Highly sensitive naked-eye and fluorescence \"turn-on\" detection of Cu(2+) using Fenton reaction assisted signal amplification. Increase of pH induced by Cu(2+)-catalyzed Fenton reaction promoted ring-opening of triazole-linked fluorescein lactone, which enabled selective \"turn-on\" fluorescent detection of Cu(2+), along with ultralow naked-eye detection limit down to 200 nM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981376"}
{"pmid": "20981357", "title": "Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular disease.", "content": "Scavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular disease. Scavenger receptors act as membrane-bound and soluble proteins that bind to macromolecular complexes and pathogens. This diverse supergroup of proteins mediates binding to modified lipoprotein particles which regulate the initiation and progression of atherosclerotic plaques. In vascular tissues, scavenger receptors are implicated in regulating intracellular signaling, lipid accumulation, foam cell development, and cellular apoptosis or necrosis linked to the pathophysiology of atherosclerosis. One approach is using gene therapy to modulate scavenger receptor function in atherosclerosis. Ectopic expression of membrane-bound scavenger receptors using viral vectors can modify lipid profiles and reduce the incidence of atherosclerosis. Alternatively, expression of soluble scavenger receptors can also block plaque initiation and progression. Inhibition of scavenger receptor expression using a combined gene therapy and RNA interference strategy also holds promise for long-term therapy. Here we review our current understanding of the gene delivery by viral vectors to cells and tissues in gene therapy strategies and its application to the modulation of scavenger receptor function in atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981357"}
{"pmid": "20981377", "title": "Local defects enhanced dehydrogenation kinetics of the NaBH(4)-added Li-Mg-N-H system.", "content": "Local defects enhanced dehydrogenation kinetics of the NaBH(4)-added Li-Mg-N-H system. A mechanistic understanding on the enhanced kinetics of hydrogen storage in the NaBH(4)-added Mg(NH(2))(2)-2LiH system is provided by carrying out experimental investigations associated with first-principles calculations. It is found that the operating temperatures for hydrogen desorption of the Mg(NH(2))(2)-2LiH system are reduced by introducing NaBH(4), and the NaBH(4) species seems almost unchanged during dehydrogenation/hydrogenation process. First-principles calculations reveal that the presence of NaBH(4) in the Mg(NH(2))(2)-2LiH system facilitates the formation of Mg vacancies in Mg(NH(2))(2). The appearance of Mg vacancies not only weakens the N-H bonds but also promotes the diffusion of atoms and/or ions, consequently resulting in the improvement of the reaction kinetics of hydrogen desorption/absorption of the NaBH(4)-added Mg(NH(2))(2)-2LiH system. This finding provides us with a deep insight into the role played by NaBH(4) in the Li-Mg-N-H system, as well as ideas for designing high-performance catalysts for metal-N-H-based hydrogen storage media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981377"}
{"pmid": "20981379", "title": "Advanced X-ray absorption and emission spectroscopy: in situ catalytic studies.", "content": "Advanced X-ray absorption and emission spectroscopy: in situ catalytic studies. Knowledge of the structure of catalysts is essential to understand their behavior, which further facilitates development of an active, selective, and stable catalyst. Determining the structure of a functioning catalyst is essential in this regard. The structure of a catalyst is prone to change during the catalytic process and needs to be determined in its working conditions. In this tutorial review, we have summarized studies done at synchrotron radiation facilities that illustrate the capability to determine catalyst structure using X-ray absorption spectroscopy (XAS) and X-ray emission spectroscopy (XES). These studies aim at facilitating the determination of the dynamic structure-performance relationships during a catalytic process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981379"}
{"pmid": "20981378", "title": "Combined XRD and infrared studies of pyridinium species in (PyH)(3)[PW(12)O(40)] single crystals.", "content": "Combined XRD and infrared studies of pyridinium species in (PyH)(3)[PW(12)O(40)] single crystals. The pyridinium salts of 12-tungstophosphoric acid (PyH)(3)[PW(12)O(40)]·2CH(3)CN (1) and (PyH)(3)[PW(12)O(40)] (2) have been prepared and studied by single crystal and powder X-ray diffraction (XRD) in order to characterize the crystallographic sites occupied by the pyridinium species. The three PyH(+) species are located on two unequivalent sites. Two species are linearly H-bonded to the oxygen atoms of the Keggins unit (α species), whereas the third one (β) forms a bent H-bond. In order to determine the infrared bands characterizing each type of pyridinium species in the 1650-1300 cm(-1) range, infrared spectra have been recorded from room temperature to 100 K. They reveal that only α pyridinium species give rise to the unusual splitting of the PyH(+)ν8b and ν19b modes, whereas β pyridinium species lead to a classical pyridinium spectrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981378"}
{"pmid": "20981380", "title": "Experimental observation of spin delocalisation onto the aryl-alkynyl ligand in the complexes [Mo(C≡CAr)(Ph2PCH2CH2PPh2)(η-C7H7)]+ (Ar = C6H5, C6H4-4-F; C7H7 = cycloheptatrienyl): an EPR and ENDOR investigation.", "content": "Experimental observation of spin delocalisation onto the aryl-alkynyl ligand in the complexes [Mo(C≡CAr)(Ph2PCH2CH2PPh2)(η-C7H7)]+ (Ar = C6H5, C6H4-4-F; C7H7 = cycloheptatrienyl): an EPR and ENDOR investigation. The paramagnetic aryl-alkynyl complexes [Mo(C≡CAr)(dppe)(η-C(7)H(7))](+) (dppe = Ph(2)PCH(2)CH(2)PPh(2); Ar = C(6)H(5), [1](+); C(6)D(5), [2](+); C(6)H(4)-4-F, [3](+); C(6)H(4)-4-Me, [5](+)) and [Mo(C≡CBu(t))(dppe)(η-C(7)H(7))](+) [4](+), have been investigated in a combined EPR and ENDOR study. Direct experimental evidence for the delocalisation of unpaired spin density over the framework of an aryl-alkynyl ligand has been obtained. The X-band solution EPR spectrum of the 4-fluoro derivative, [3](+), exhibits resolved hyperfine coupling to the remote para position of the aryl group [a(iso)((19)F) = 4.5 MHz, (1.6 G)] in addition to couplings attributable to (95/97)Mo, (31)P and (1)H of the C(7)H(7) ring. A full analysis of the (1)H ENDOR spectra is restricted by the low g anisotropy of the system which prevents the use of orientation selection. However, inter-comparison of the (1)H cw-ENDOR frozen solution spectra of [1](+), [2](+), [4](+) and [5](+), combined with spectral simulation informed by calculated values derived from DFT investigations, has facilitated estimation of the experimental a(iso)((1)H) hyperfine couplings of [1](+) including the ortho, ±3.7 MHz (±1.3 G) and para, ±3.9 MHz (±1.4 G) positions of the C(6)H(5) substituent of the aryl-alkynyl ligand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981380"}
{"pmid": "20981381", "title": "Entrapping homogeneous catalysts by sol-gel methods: the bottom-up synthesis of catalysts that recycle and cascade.", "content": "Entrapping homogeneous catalysts by sol-gel methods: the bottom-up synthesis of catalysts that recycle and cascade. Homogeneous catalysts entrapped in silica matrices, including ionic liquid containing 'ionogels', exhibit high selectivity, unexpected activity and excellent recyclability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981381"}
{"pmid": "20981382", "title": "Chlorometallate(III) ionic liquids as Lewis acidic catalysts--a quantitative study of acceptor properties.", "content": "Chlorometallate(III) ionic liquids as Lewis acidic catalysts--a quantitative study of acceptor properties. The Gutmann Acceptor Number (AN), which is a quantitative measure of Lewis acidity, has been estimated using the (31)P NMR chemical shift of a probe molecule, triethylphosphine oxide, for a range of chlorometallate(III) ionic liquids, based on Group 13 metals (aluminium(III), gallium(III) and indium(III)) and the 1-octyl-3-methylimidazolium cation, at different compositions. The results were interpreted in terms of extant speciation studies of chlorometallate(III) ionic liquids, and compared with a range of standard molecular solvents and acids. The value of these data were illustrated in terms of the selection of appropriate ionic liquids for specific applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981382"}
{"pmid": "20981384", "title": "Multi-chelation approach towards natural product-like skeletons: one-pot access to a nitrogen-containing tetracyclic framework from AlaAla dipeptide.", "content": "Multi-chelation approach towards natural product-like skeletons: one-pot access to a nitrogen-containing tetracyclic framework from AlaAla dipeptide. Reductive transformation of the dipeptide BocAlaAlaOMe to a complex, internally charge-stabilized, natural product-like skeleton in one synthetic step is discussed. Stepwise replacement of the B-H bonds in borane by B-N or B-O resulted in incorporation of three boron atoms in a tetracyclic framework whereby one is stereogenic!", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981384"}
{"pmid": "20981385", "title": "Ligand influence in the selective gold-mediated synthesis of allenes.", "content": "Ligand influence in the selective gold-mediated synthesis of allenes. The use of [(IPr)AuOH] permits the generation of gold(i)-amine complexes by a silver-free protocol. These in situ or well-defined complexes are used in a straightforward synthetic route to substituted allenes from propargylic acetates. The catalytic activity can be modulated as a function of the nature of the ligand bound to the gold-NHC moiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981385"}
{"pmid": "20981383", "title": "Efficacy of surface sampling methods for different types of beryllium compounds.", "content": "Efficacy of surface sampling methods for different types of beryllium compounds. The objective of the research work was to evaluate the efficiency of three different sampling methods (Ghost Wipe™, micro-vacuum, and ChemTest®) in the recovery of Be dust by assessing: (1) four Be compounds (beryllium acetate, beryllium chloride, beryllium oxide and beryllium aluminium), (2) three different surfaces (polystyrene, glass and aluminium) and (3) inter-operator variation. The three sampling methods were also tested on site in a laboratory of a dental school for validation purposes. The Ghost Wipe™ method showed recovery ranging from 43.3% to 85.8% for all four Be compounds and for all three quantities of Be spiked on Petri dishes, while recovery with the micro-vacuum method ranged from 0.1% to 12.4%. On polystyrene dishes with 0.4 µg Be, the recovery ranged from 48.3% to 81.7%, with an average recovery of 59.4% for Operator 1 and 68.4% for Operator 2. The ChemTest® wipe method with beryllium acetate, beryllium chloride, and AlBeMet® showed analogous results that are in line with the manufacturer's manual, but collection of beryllium oxide was negative. In the dental laboratory, Ghost Wipe™ samplings showed better recovery than the micro-vacuum method. The ratios between the recovered quantities of Be in each location where the Ghost Wipe™ was tested differed substantially, ranging from 1.45 to 64. In the dental laboratory, a faint blue color indicating the presence of Be was observed on the ChemTest® wipes used in two locations out of six. In summary, the Ghost Wipe™ method was more efficient than micro-vacuuming in collecting the Be dust from smooth, non-porous surfaces such as Petri dishes by a factor of approximately 18. The results obtained on site in a dental laboratory also showed better recovery with Ghost Wipes™. However, the ratio of Be recovered by Ghost Wipes™ versus micro-vacuuming was much lower for surfaces where a large amount of dust was present. Wet wiping is preferred over micro-vacuuming for beryllium forms, but this conclusion probably applies to the ultra-low particulate loading levels (0.4 micrograms or less) which was tested in this study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981383"}
{"pmid": "20981386", "title": "Risk assessment of soils contaminated by mercury mining, Northern Spain.", "content": "Risk assessment of soils contaminated by mercury mining, Northern Spain. Analytical results of soil samples taken in three different mercury mining sites in Northern Spain are studied to assess the potential adverse health effects of the exposure to trace elements associated with the mining process. Doses contacted through ingestion and inhalation and the dose absorbed through the skin were calculated using USEPA's exposure parameters and the US Department of Energy's toxicity values. The results of the risk assessment indicate that the highest risk is associated with ingestion of soil particles and that the trace element of major concern is arsenic, the exposure to which results in a high cancer risk value for all the sites ranging from 3.3 × 10(-5) to 3.6 × 10(-3), well above the 1 × 10(-5) probability level deemed unacceptable by most regulatory agencies. Regarding non-cancer effects, exposure to polluted soils yields an aggregate hazard index above the threshold value of 1 for all three sites, with As and Hg as the main contributors. Risk assessment has proven to be a very useful tool to identify the contaminants and exposure pathways of most concern in the soils from metal mining sites, as well as to categorize them in terms of action priority to ensure fitness for use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981386"}
{"pmid": "20981387", "title": "Synthesis of (±)-desethylrhazinal using a tandem radical addition-cyclization process.", "content": "Synthesis of (±)-desethylrhazinal using a tandem radical addition-cyclization process. The indolizidine ring system present in (±)-rhazinal, was assembled using a xanthate-based sequential intermolecular radical addition-cyclization process. The novel (±)-desethylrhazinal was prepared in seven steps in approximately 12% overall yield from 2-formylpyrrole, using this strategy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981387"}
{"pmid": "20981388", "title": "Synthesis and aggregation properties of dissymmetric phytanyl-gemini surfactants for use as improved DNA transfection vectors.", "content": "Synthesis and aggregation properties of dissymmetric phytanyl-gemini surfactants for use as improved DNA transfection vectors. Improvements in transfection efficiency are required in order to make the goal of cellular gene delivery by non-viral vectors realizable. Novel derivatives of gemini surfactants having dissymmetric tail groups have been designed specifically as a means to improve DNA transfection; the micelle and interfacial properties are reported herein. The effect of these substitutions on the aggregation properties of the gemini surfactants is discussed in the context of results for the m-3-m gemini series, previously reported in the literature. Phytanyl substitution results in lower cmc and higher micelle ionization. In addition, the phytanyl substituted gemini surfactants form vesicles at room temperature. Preliminary in vitro transfection assays showed the phytanyl substituted gemini surfactants to be more efficient transfection vectors as compared to symmetric gemini surfactants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981388"}
{"pmid": "20981389", "title": "Structure and synthesis of 2-aminoimidazole alkaloids from Leucetta and Clathrina sponges.", "content": "Structure and synthesis of 2-aminoimidazole alkaloids from Leucetta and Clathrina sponges. Marine sponges belonging to the Calcarea family have been studied for some time and have yielded a wide variety of structurally unique secondary metabolites. In particular, these sponges have produced a large number of bioactive alkaloids containing an imidazole heterocycle, typically substituted with two benzylic fragments at various locations around the azole nucleus and at various oxidation states. This review will describe the isolation, structural determination and synthetic studies towards this growing class of natural products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981389"}
{"pmid": "20981391", "title": "Copper-catalyzed atom transfer radical addition (ATRA) and cyclization (ATRC) reactions in the presence of environmentally benign ascorbic acid as a reducing agent.", "content": "Copper-catalyzed atom transfer radical addition (ATRA) and cyclization (ATRC) reactions in the presence of environmentally benign ascorbic acid as a reducing agent. In recent years, copper-catalyzed atom transfer radical addition (ATRA) has emerged as a viable organic procedure for the formation of carbon-carbon bonds starting from alkyl halides and alkenes. Studies have primarily focused on the use of free-radical initiators to regenerate the copper(I) complex or activator in situ. Although these initiators led to a significant decrease in the amount of metal catalyst, they were much less effective for highly active alkenes that readily undergo free-radical polymerization. In this study, the non-radical reducing agent ascorbic acid (commonly known as Vitamin C) was effectively employed resulting in TONs as high as 15,200 in the homogenous ATRA of polyhalogenated compounds to α-olefins, and enabling selective monoadduct formation for highly active alkenes such as acrylonitrile (TONs as high as 11,800). As low as 7-20 mol% of ascorbic acid relative to substrate was sufficient for all ATRA and ATRC reactions examined. Further, product isolations for all selected syntheses were quite facile and nearly quantitative, requiring only simple liquid-liquid extraction techniques. Reactions in the presence of ascorbic acid were also examined kinetically via (1)H NMR and UV/Vis spectroscopy. A half order rate dependence on reducing agent concentration was observed, but the first order kinetic plots became nonlinear as the concentration of ascorbic acid was increased. Finally, the use of ascorbic acid circumvented otherwise necessary purging techniques, successfully furthering the utility of these reactions in organic synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981391"}
{"pmid": "20981390", "title": "Infrared microspectroscopy of live cells in aqueous media.", "content": "Infrared microspectroscopy of live cells in aqueous media. Fourier Transform Infrared (FTIR) spectroscopic measurements of individual, live HeLa cells in culture and buffer media are presented. Spectral data were acquired using a newly designed live cell chamber developed in the authors' laboratory. Data were processed using MATLAB-based routines that correct for the overcompensation of water encountered during live cell measurements in aqueous samples. Data presented are from live cells monitored over an extended period of time as well as a comparison of live cells exposed to perturbing conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981390"}
{"pmid": "20981393", "title": "Iridium(III) molecular catalysts for water oxidation: the simpler the faster.", "content": "Iridium(III) molecular catalysts for water oxidation: the simpler the faster. We report on three Ir(iii) molecular catalysts for water oxidation: 1, [Cp*Ir(ppy)Cl]; 2, [Cp*Ir(bzpy)NO(3)]; 3, [Cp*Ir(H(2)O)(3)](NO(3))(2). 2 and 3 are water-soluble and show a long-term activity ca. 2 and 3 times higher than 1. It is remarkable that 3, having the simplest structure, is the catalyst with the highest activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981393"}
{"pmid": "20981392", "title": "Highly sensitive and selective turn-on fluorescent and chromogenic probe for Cu2+ and ClO- based on a N-picolinyl rhodamine B-hydrazide derivative.", "content": "Highly sensitive and selective turn-on fluorescent and chromogenic probe for Cu2+ and ClO- based on a N-picolinyl rhodamine B-hydrazide derivative. A new rhodamine B-based dual-function chromo- and fluorogenic probe for Cu(2+) and ClO(-) has been designed, synthesized, and characterized. The probe comprises a spectroscopic unit of rhodamine B and a Cu(2+)-specific chelating unit of pyridinecarboxamide as well as a ClO(-)-specific reactive moiety of diacylhydrazine, and is a highly selective and extremely sensitive fluorescent and colorimetric sensor for Cu(2+) and ClO(-) in different pH conditions. Compared with the reported probes for Cu(2+) or ClO(-), this is the first chemosensor based on a small molecule that can detect both Cu(2+) and ClO(-), respectively, at 1 nM level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981392"}
{"pmid": "20981394", "title": "Fluorometric paired emitter detector diode (FPEDD).", "content": "Fluorometric paired emitter detector diode (FPEDD). Integration of two light emitting diodes allows construction of a fluorometric paired emitter detector diode (FPEDD)--a compact optoelectronic device useful as a complete flow-through fluorescence detector.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981394"}
{"pmid": "20981396", "title": "Mobilization of very small embryonic-like stem cells in acute coronary syndromes and stroke.", "content": "Mobilization of very small embryonic-like stem cells in acute coronary syndromes and stroke. The bone marrow (BM) niche contains small heterogenous populations of cells which may contribute to cardiac and endothelial repair, including committed lineages [endothelial progenitor cells (EPCs), multipotent mesenchymal stromal cells (MSCs) and more primitive very small embryonic-like cells (VSELs) expressing pluripotent stem cell (PSC) markers (Oct-4, Nanog, SSEA-1)]. VSELs are present in BM, peripheral blood and some solid organs in mice and were recently identified in peripheral blood in patients with acute coronary syndromes and stroke. VSELs can be expanded in vitro and differentiated into cells from all three germ layers. This population of cells displays the morphology of primitive PSC (small size, open type chromatin, large nucleus, narrow rim of cytoplasm) and express PSC markers. The isolation of human VSELs is based on their size and presence of several surface markers (CXCR4, CD133, CD34) and lack of markers of hematopoietic lineage (lin, CD45). In acute myocardial infarction and ischemic stroke VSELs are rapidly mobilized into peripheral blood, and express increased levels of PSC markers as well as early cardiac (GATA-4, Nkx2.5/Csx), neural (GFAP, nestin, beta-III-tubulin, Olig1, Olig2, Sox2, Musashi) and endothelial lineage markers (VE-cadherin, von Willebrand factor). The number of VSELs mobilized in acute myocardial infarction is inversely correlated with left ventricular ejection fraction and the release of cardiac necrosis markers. Mobilization of these cells is also reduced in patients with diabetes and in the elderly. BM-derived VSELs were expanded and after cardiogenic pre-differentiation injected intramyocardially in mice models of myocardial infarction leading to improved left ventricular contractility. VSELs are probably progeny of epiblast cells which migrated to the BM and developing organs during embryonic development. The cells are present in a quiescent state in the adult BM and solid organs and might serve as a reserve pool of resident stem cells. VSELs are promising candidates for further pre-clinical and clinical studies on cellular cardiovascular therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981396"}
{"pmid": "20981397", "title": "Cardiac allograft vasculopathy : complications and imaging studies.", "content": "Cardiac allograft vasculopathy : complications and imaging studies. Cardiac allograft vasculopathy (CAV) is an accelerated form of coronary artery disease affecting both intramyocardial and epicardial coronary arteries and is observed in patients during long-term survival after cardiac transplantation. We report a case of CAV complicated with silent transmural myocardial infarction and massive left ventricular thrombus formation associated with silent pericarditis and with ischemic and non-ischemic scar tissue, as detected by cardiac magnetic resonance imaging (CMRI). The authors suggest CMRI as an additional technique along with echocardiography during follow-up of heart transplant recipients. CMRI may contribute to the early identification of areas of myocardial wall abnormalities suggestive of CAV, thus guiding diagnosis and prompt percutaneous treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981397"}
{"pmid": "20981400", "title": "Evaluation of salinity tolerance and analysis of allelic function of HvHKT1 and HvHKT2 in Tibetan wild barley.", "content": "Evaluation of salinity tolerance and analysis of allelic function of HvHKT1 and HvHKT2 in Tibetan wild barley. Tibetan wild barley is rich in genetic diversity with potential allelic variation useful for salinity-tolerant improvement of the crop. The objectives of this study were to evaluate salinity tolerance and analysis of the allelic function of HvHKT1 and HvHKT2 in Tibetan wild barley. Salinity tolerance of 189 Tibetan wild barley accessions was evaluated in terms of reduced dry biomass under salinity stress. In addition, Na(+) and K(+) concentrations of 48 representative accessions differing in salinity tolerance were determined. Furthermore, the allelic and functional diversity of HvHKT1 and HvHKT2 was determined by association analysis as well as gene expression assay. There was a wide variation among wild barley genotypes in salt tolerance, with some accessions being higher in tolerance than cultivated barley CM 72, and salinity tolerance was significantly associated with K(+)/Na(+) ratio. Association analysis revealed that HvHKT1 and HvHKT2 mainly control Na(+) and K(+) transporting under salinity stress, respectively, which was validated by further analysis of gene expression. The present results indicated that Tibetan wild barley offers elite alleles of HvHKT1 and HvHKT2 conferring salinity tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981400"}
{"pmid": "20981401", "title": "Variation of GmIRCHS (Glycine max inverted-repeat CHS pseudogene) is related to tolerance of low temperature-induced seed coat discoloration in yellow soybean.", "content": "Variation of GmIRCHS (Glycine max inverted-repeat CHS pseudogene) is related to tolerance of low temperature-induced seed coat discoloration in yellow soybean. In yellow soybean, seed coat pigmentation is inhibited by post-transcriptional gene silencing (PTGS) of chalcone synthase (CHS) genes. A CHS cluster named GmIRCHS (Glycine max inverted-repeat CHS pseudogene) is suggested to cause PTGS in yellow-hilum cultivars. Cold-induced seed coat discoloration (CD), a commercially serious deterioration of seed appearance, is caused by an inhibition of this PTGS upon exposure to low temperatures. In the highly CD-tolerant cultivar Toyoharuka, the GmIRCHS structure differs from that of other cultivars. The aim of this study was to determine whether the variation of GmIRCHS structure among cultivars is related to variations in CD tolerance. Using two sets of recombinant inbred lines between Toyoharuka and CD-susceptible cultivars, we compared the GmIRCHS genotype and CD tolerance phenotype during low temperature treatment. The GmIRCHS genotype was related to the phenotype of CD tolerance. A QTL analysis around GmIRCHS showed that GmIRCHS itself or a region located very close to it was responsible for CD tolerance. The variation in GmIRCHS can serve as a useful DNA marker for marker-assisted selection for breeding CD tolerance. In addition, QTL analysis of the whole genome revealed a minor QTL that also affected CD tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981401"}
{"pmid": "20981402", "title": "Identification of QTLs for morphological traits influencing waterlogging tolerance in perennial ryegrass (Lolium perenne L.).", "content": "Identification of QTLs for morphological traits influencing waterlogging tolerance in perennial ryegrass (Lolium perenne L.). Perennial ryegrass is a globally cultivated obligate outbreeding diploid species (2n = 2x = 14) which is subjected to periods of waterlogging stress due to flood irrigation during winter and the lead-up to summer. Reduction of oxygen supply to root systems due to waterlogging produces consequent deleterious effects on plant performance. Framework genetic maps for a large-scale genetic mapping family [F₁(NA(x) × AU₆)] were constructed containing 91 simple sequence repeat and 24 single nucleotide polymorphism genetic markers. Genetic trait dissection using both control and waterlogging treatments was performed in the glasshouse, a total of 143 maximally recombinant genotypes being selected from the overall sib-ship and replicated threefold in the trial. Analysis was performed for nine quantitative morphological traits measured 8 weeks after stress treatments were applied. A total of 37 quantitative trait loci (QTLs) were identified; 19 on the NA(x) parental genetic map, and 18 on the AU₆ parental genetic map. Regions of particular interest were identified on linkage groups (LGs) 4 and 3 of the respective maps, which have been targeted for further analysis by selection of critical recombinants. This first study of genetic control of waterlogging tolerance in ryegrasses has important implications for breeding improvement of abiotic stress adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981402"}
{"pmid": "20981403", "title": "Mapping quantitative trait loci for seed size traits in soybean (Glycine max L. Merr.).", "content": "Mapping quantitative trait loci for seed size traits in soybean (Glycine max L. Merr.). Seed size traits in soybean--length, width and thickness--and their corresponding ratios--length-to-width, length-to-thickness and width-to-thickness--play a crucial role in determining seed appearance, quality and yield. In this study, an attempt was made to detect quantitative trait loci (QTL) for the aforementioned seed size traits in F(2:3), F(2:4) and F(2:5) populations from the direct and reciprocal crosses of Lishuizhongzihuang with Nannong 493-1, using multi-QTL joint analysis (MJA) along with composite interval mapping (CIM). A total of 121 main-effect QTL (M-QTL), six environmental effects, eight environment-by-QTL interactions, five cytoplasmic effects and 92 cytoplasm-by-QTL interactions were detected. Fifty-two common M-QTL across MJA and CIM, 21 common M-QTL in more than two populations and 5 M-QTL in all three populations showed the stability of the results. Five M-QTL had higher heritability, greater than 20%. In addition, 28 cytoplasm-by-QTL and 4 environment-by-QTL interactions were confirmed by CIM. Most M-QTL were clustered in eight chromosomal regions. Our results provide a good foundation for fine mapping, cloning and designed molecular breeding of favorable genes related to soybean seed size traits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981403"}
{"pmid": "20981404", "title": "Fine mapping and analyses of R ( SC8 ) resistance candidate genes to soybean mosaic virus in soybean.", "content": "Fine mapping and analyses of R ( SC8 ) resistance candidate genes to soybean mosaic virus in soybean. Soybean mosaic virus (SMV) in soybean [Glycine max (L.) Merr.] is a destructive foliar disease in soybean-producing countries worldwide. In this study, F(2), F(2:3), and F(7:11) recombinant inbred lines populations derived from Kefeng No.1 × Nannong 1138-2 were used to study inheritance and linkage mapping of the SMV strain SC8 resistance gene in Kefeng No.1. Results indicated that a single dominant gene (designated R(SC8)) controls resistance, which is located on chromosome 2 (MLG D1b). A mixed segregating population was developed by selfing two heterozygous plants (RHL153-1 and RHL153-2) at four markers adjacent to the locus and used in fine mapping R(SC8). In addition, two genomic-simple sequence repeats (SSR) markers BARCSOYSSR_02_0610 and BARCSOYSSR_02_0616 were identified that flank the two sides of R(SC8). Sequence analysis of the soybean genome indicated that the interval between the two genomic-SSR markers is 200 kb. QRT-PCR analysis of the candidate genes determined that five genes (Glyma02g13310, 13320, 13400, 13460, and 13470) are likely involved in soybean SMV resistance. These results will have utility in cloning, transferring, and pyramiding of the R(SC8) through marker-assisted selection in soybean breeding programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981404"}
{"pmid": "20981405", "title": "BK channels affect glucose homeostasis and cell viability of murine pancreatic beta cells.", "content": "BK channels affect glucose homeostasis and cell viability of murine pancreatic beta cells. Evidence is accumulating that Ca(2+)-regulated K(+) (K(Ca)) channels are important for beta cell function. We used BK channel knockout (BK-KO) mice to examine the role of these K(Ca) channels for glucose homeostasis, beta cell function and viability. Glucose and insulin tolerance were tested with male wild-type and BK-KO mice. BK channels were detected by single-cell RT-PCR, cytosolic Ca(2+) concentration ([Ca(2+)](c)) by fura-2 fluorescence, and insulin secretion by radioimmunoassay. Electrophysiology was performed with the patch-clamp technique. Apoptosis was detected via caspase 3 or TUNEL assay. BK channels were expressed in murine pancreatic beta cells. BK-KO mice were normoglycaemic but displayed markedly impaired glucose tolerance. Genetic or pharmacological deletion of the BK channel reduced glucose-induced insulin secretion from isolated islets. BK-KO and BK channel inhibition (with iberiotoxin, 100 nmol/l) broadened action potentials and abolished the after-hyperpolarisation in glucose-stimulated beta cells. However, BK-KO did not affect action potential frequency, the plateau potential at which action potentials start or glucose-induced elevation of [Ca(2+)](c). BK-KO had no direct influence on exocytosis. Importantly, in BK-KO islet cells the fraction of apoptotic cells and the rate of cell death induced by oxidative stress (H(2)O(2), 10-100 μmol/l) were significantly increased compared with wild-type controls. Similar effects were obtained with iberiotoxin. Determination of H(2)O(2)-induced K(+) currents revealed that BK channels contribute to the hyperpolarising K(+) current activated under conditions of oxidative stress. Ablation or inhibition of BK channels impairs glucose homeostasis and insulin secretion by interfering with beta cell stimulus-secretion coupling. In addition, BK channels are part of a defence mechanism against apoptosis and oxidative stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981405"}
{"pmid": "20981406", "title": "Indocyanine green plasma disappearance rate for monitoring hepatosplanchnic blood flow.", "content": "Indocyanine green plasma disappearance rate for monitoring hepatosplanchnic blood flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981406"}
{"pmid": "20981407", "title": "The diagnostic future for bloodstream infections?", "content": "The diagnostic future for bloodstream infections?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981407"}
{"pmid": "20981408", "title": "Swept under the carpet? The role of mucociliary clearance in ventilator-induced lung injury.", "content": "Swept under the carpet? The role of mucociliary clearance in ventilator-induced lung injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981408"}
{"pmid": "20981409", "title": "Effects of different mechanical ventilation strategies on the mucociliary system.", "content": "Effects of different mechanical ventilation strategies on the mucociliary system. To evaluate the effects of different mechanical ventilation (MV) strategies on the mucociliary system. Experimental study. Twenty-seven male New Zealand rabbits. After anesthesia, animals were tracheotomized and ventilated with standard ventilation [tidal volume (Vt) 8 ml/kg, positive end expiratory pressure (PEEP) 5 cmH(2)O, flow 3 L/min, FiO(2) 0.4] for 30 min. Next, animals were randomized into three groups and ventilated for 3 h with low volume (LV): Vt 8 ml/kg, PEEP 5 cmH(2)O, flow 3 L/min (n = 6); high volume (HV): Vt 16 ml/kg, PEEP 5 cmH(2)O, flow 5 L/min (n = 7); or high pressure (HP): Ppeak 30 cmH(2)O, PEEP 12 cmH(2)O (n = 8). Six animals (controls) were ventilated for 10 min with standard ventilation. Vital signals, blood lactate, and respiratory system mechanics were verified. Tracheal tissue was collected before and after MV. Lung and tracheal tissue sections were stained to analyze inflammation and mucosubstances by the point-counting method. Electron microscopy verified tracheal cell ultrastructure. In situ tracheal ciliary beating frequency (CBF), determined using a videoscopic technique, and tracheal mucociliary transport (TMCT), assessed by stereoscopic microscope, were evaluated before and after MV. Respiratory compliance decreased in the HP group. The HV and HP groups showed higher lactate levels after MV. Macroscopy showed areas of atelectasis and congestion on HV and HP lungs. Lung inflammatory infiltrate increased in all ventilated groups. Compared to the control, ventilated animals also showed a reduction of total and acid mucus on tracheal epithelium. Under electron microscopy, injury was observed in the ciliated cells of the HP group. CBF decreased significantly after MV only in the HP group. TMCT did not change significantly in the ventilated groups. Different MV strategies induce not only distal lung alterations but also morphological and physiological tracheal alterations leading to mucociliary system dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981409"}
{"pmid": "20981410", "title": "Production of liver preneoplasia and gallbladder agenesis in turkey fetuses administered diethylnitrosamine.", "content": "Production of liver preneoplasia and gallbladder agenesis in turkey fetuses administered diethylnitrosamine. The in ovo carcinogenicity assessing (IOCA) assay was used to examine the morphological changes in fetal turkey livers caused by the DNA-reactive carcinogen diethylnitrosamine (DEN). Fertilized turkey eggs were allocated into 3 groups: nondosed control (NDC), vehicle (water) control (VC) and DEN-dosed. At day 0, the fertilized eggs of the dosed groups were injected with 1 (LD) or 4 (HD) mg/egg (about 12.5 or 50 mg/kg egg) of DEN and the VC were injected with water. All eggs were allowed to incubate at 37°C and 60% humidity for 24 days. The fetal livers were collected and processed for histopathological evaluation (H&E staining). Typical survival rates were 82% for the NDC, 50% for the VC and 16-65% for the DEN-dosed fetuses. No difference in histology was found between NDC and VC control groups. Both DEN concentrations produced dose-related liver findings consisting of foci of altered hepatocytes (FAH), which had assumed a tubular cord (glandular) pattern, and in HD DEN group the FAH assumed a tumor-like morphology. In addition, the high DEN dose produced gallbladder agenesis. Thus, DEN produced both hepatocellular transformation (FAH) similar to preneoplastic microscopic changes in adult rodents, reflecting disruption of the fetal processes of differentiation and proliferation, and also teratogenicity (gallbladder agenesis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981410"}
{"pmid": "20981412", "title": "The antidepressant-like effect of the 3β-hydroxysteroid dehydrogenase inhibitor trilostane involves a regulation of β-type estrogen receptors.", "content": "The antidepressant-like effect of the 3β-hydroxysteroid dehydrogenase inhibitor trilostane involves a regulation of β-type estrogen receptors. Trilostane is a competitive inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD), which notably converts pregnenolone into progesterone or dehydroepiandrosterone into androstenedione. Trilostane shows antidepressant-like properties in the forced swimming test (FST). The compound, however, induced only moderate effects on neuroactive steroid levels that could be related to its behavioral efficacy. We compared the behavioral effect of trilostane with the other 3β-HSD inhibitor, cyanoketone, and analyzed the putative involvement of the β-type estrogen receptor (ERβ) in its antidepressant effect. Trilostane reduced immobility in the FST significantly at 12.5 and 25 mg/kg subcutaneously (s.c.), whereas cyanoketone (0-100 mg/kg s.c.) was ineffective. The negative ER modulator fulvestrant (ICI 182780) dose-dependently blocked the effect of trilostane (25 mg/kg). Trilostane increased circulating estradiol levels in the 12.5-50 mg/kg dose-range, and this effect was unaffected by stress and not shared by cyanoketone (25 mg/kg). The trilostane (25 mg/kg) treatment increased the ERβ mRNA expression in adrenals (+100%) and centrally, in the hippocampus (+330%). Stress and cyanoketone failed to affect ERβ mRNA levels in periphery or in the brain. These data demonstrate that the antidepressant-like potential of trilostane is not due to its 3β-HSD inhibiting activity, since it is not shared by cyanoketone, but rather to its estrogenic activity. The compound, which releases estradiol and up-regulates ERβ receptors, could be used as a therapeutic tool to allow an estrogenic facilitation of antidepressant efficacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981412"}
{"pmid": "20981411", "title": "Prefrontal stimulation of GABAA receptors counteracts the corticolimbic hyperactivity produced by NMDA antagonists in the prefrontal cortex of the rat.", "content": "Prefrontal stimulation of GABAA receptors counteracts the corticolimbic hyperactivity produced by NMDA antagonists in the prefrontal cortex of the rat. The hypofunction of NMDA receptors in the prefrontal cortex (PFC) has been suggested to produce corticolimbic hyperactivity through the reduction of cortical GABA transmission. The present study investigates the effects of injections of the NMDA antagonist 3-[(R)-2-carboxypiperazin-4-yl]-propyl-1-phosphonic acid (CPP) into the PFC on (1) the release of dopamine and/or acetylcholine in the amygdala and hippocampus, (2) the levels of corticosterone in the hippocampus and (3) spontaneous motor activity. Also, the stimulation of GABA(A) receptors, by prefrontal injections of muscimol, on the effects produced by NMDA antagonists on these same neurochemical, hormonal and behavioural parameters was evaluated. Male Wistar rats were implanted with guide cannulae to perform bilateral microinjections into the PFC and microdialysis experiments in the amygdala and/or ventral hippocampus, simultaneously. Spontaneous motor activity was monitored in the open field. Injections of CPP (1 μg/0.5 μl) into the PFC increased dialysate concentrations of dopamine and acetylcholine in the amygdala, acetylcholine and free corticosterone in the hippocampus and also motor activity. Simultaneous injections of muscimol (0.5 μg/0.5 μl) into the PFC counteracted the increases of dopamine and acetylcholine in the amygdala and hippocampus and also significantly reduced the peak increase of corticosterone in the hippocampus. Injections of muscimol (0.05 and 0.5 μg/0.5 μl) reduced the increases of motor activity produced by prefrontal NMDA antagonists. These results suggest that the hypofunction of NMDA receptors in the PFC produces corticolimbic hyperactivity through the activation of prefrontal efferent projections to subcortical/limbic areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981411"}
{"pmid": "20981413", "title": "Cellular correlates of anxiety in CA1 hippocampal pyramidal cells of 5-HT1A receptor knockout mice.", "content": "Cellular correlates of anxiety in CA1 hippocampal pyramidal cells of 5-HT1A receptor knockout mice. 5-HT(1A) receptor knockout (1AKO) mice have a robust anxiety phenotype. Tissue-specific \"rescue\" strategies and electrophysiology have implicated a critical role for postsynaptic 5-HT(1A) receptors, particularly in the CA1 region of the hippocampus. In this study, we evaluated differences in membrane properties and synaptic activity in CA1 hippocampal pyramidal cells between 1AKOs and wild-type (WT) controls to better understand the cellular correlates of anxiety in this mouse model. Whole-cell patch-clamp recordings were conducted in CA1 pyramidal cells in hippocampal brain slices from 1AKOs and WTs that had previously been screened for anxiety with the elevated-plus maze. Spontaneous miniature inhibitory and excitatory postsynaptic currents (IPSCs and EPSCs) and stimulus-evoked eIPSCs and eEPSCs were recorded in addition to the effect of the benzodiazepine agonist diazepam or the inverse agonist FG 7142 on γ-aminobutyric acid (GABA)ergic eIPSCs. Evoked EPSC amplitude was greater in 1AKOs than WTs. When subjects were pooled across genotypes, anxiety measures correlated with eEPSC amplitude, indicating enhanced postsynaptic glutamate synaptic activity under conditions of synaptic activation in anxious subjects. While GABA synaptic activity and sensitivity to diazepam were not affected by genotype or correlated with anxiety, sensitivity to the anxiogenic FG 7142 was smaller in anxious subjects. These data indicate enhanced postsynaptic glutamate receptor sensitivity and decreased GABAergic inhibition by a benzodiazepine inverse agonist in CA1 hippocampal neurons of anxious mice are produced by deletion of the 5-HT(1A) receptor. These data provide new information about interactions between 5-HT, GABA, and glutamate systems during the expression of chronic anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981413"}
{"pmid": "20981414", "title": "An in vitro study of silk stent morphology.", "content": "An in vitro study of silk stent morphology. Morphology of the Silk stent (Balt, Montmorency, France) after deployment is not fully understood, especially in tortuous vessels. An in vitro study was conducted to study morphology and flow-diverting parameters of this stent. Two sets of different-sized and curved polytetrafluoroethylene tubes were studied. To simulate the aneurysm neck, a small hole was created in a tube. A stent was placed in each of the different tubes. Angiographic computerized tomography and macroscopic photography were then obtained. The images were analyzed to calculate a Percentage of Area Coverage (PAC). Good stent conformability was observed. The PAC was 21% in the straight model with matched stent and vessel diameter. In the straight model with an oversized stent, the PAC was increased. In the curved models, dynamic wire repositioning occurred. The repositioning was affected by the size of the stent and the angle of the vessel curve. Compared to the straight model, this increased the PAC in two instances: on the convexity (oversized stent), and on the concavity (matched stent and vessel diameter). The PAC did not significantly change at the sides of the curve. By design, the wires of the silk stent move relative to each other. In a curved model, the PAC is different at the convexity, concavity, and lateral walls. The stent diameter affects the PAC. These results are clinically relevant because it is desirable to maximize and minimize the PAC across the aneurysm neck and branch vessel orifice, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981414"}
{"pmid": "20981415", "title": "Development of laminar organization of the fetal cerebrum at 3.0T and 7.0T: a postmortem MRI study.", "content": "Development of laminar organization of the fetal cerebrum at 3.0T and 7.0T: a postmortem MRI study. The purpose of this study is to show the condition of laminar organization on 3.0T and 7.0T postmortem magnetic resonance imaging (MRI) and analyze developmental changes. Heads of 131 fetal specimens of 14-40 weeks gestational age (GA) were scanned by 3.0T MRI. Eleven fetal specimens of 14-27 weeks GA were scanned by 7.0T MRI. Clear images were chosen for analysis. On T₁-weighted 3.0T MRI, layers could be visualized at 14 weeks GA and appeared clearer after 18 weeks GA. On 7.0T MRI, four zones could be recognized at 14 weeks GA. During 15-22 weeks GA, when laminar organization appeared typical, seven layers including the periventricular zone and external capsule fibers could be differentiated, which corresponded to seven zones in histological stained sections. At 23-28 weeks GA, laminar organization appeared less typical, and borderlines among them appeared obscured. After 30 weeks GA, it disappeared and turned into mature-like structures. The developing lamination appeared the most distinguishable at the parieto-occipital part of brain and peripheral regions of the hippocampus. The migrating thalamocortical afferents were probably delineated as a high signal layer located at the lower, middle, and upper part of the subplate zone at 16-28 weeks GA on T₁-weighted 3.0T MRI. T₁-weighted 3.0T MRI and T₂-weighted 7.0T MRI can well demonstrate the laminar organization. Development of the lamination follows a specific spatio-temporal regularity, and postmortem MRI of the parieto-occipital part of brain obtained with 3.0T or 7.0T is an effective way to show developmental changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981415"}
{"pmid": "20981416", "title": "Evolution of conserved non-coding sequences within the vertebrate Hox clusters through the two-round whole genome duplications revealed by phylogenetic footprinting analysis.", "content": "Evolution of conserved non-coding sequences within the vertebrate Hox clusters through the two-round whole genome duplications revealed by phylogenetic footprinting analysis. As a result of two-round whole genome duplications, four or more paralogous Hox clusters exist in vertebrate genomes. The paralogous genes in the Hox clusters show similar expression patterns, implying shared regulatory mechanisms for expression of these genes. Previous studies partly revealed the expression mechanisms of Hox genes. However, cis-regulatory elements that control these paralogous gene expression are still poorly understood. Toward solving this problem, the authors searched conserved non-coding sequences (CNSs), which are candidates of cis-regulatory elements. When comparing orthologous Hox clusters of 19 vertebrate species, 208 intergenic conserved regions were found. The authors then searched for CNSs that were conserved not only between orthologous clusters but also among the four paralogous Hox clusters. The authors found three regions that are conserved among all the four clusters and eight regions that are conserved between intergenic regions of two paralogous Hox clusters. In total, 28 CNSs were identified in the paralogous Hox clusters, and nine of them were newly found in this study. One of these novel regions bears a RARE motif. These CNSs are candidates for gene expression regulatory regions among paralogous Hox clusters. The authors also compared vertebrate CNSs with amphioxus CNSs within the Hox cluster, and found that two CNSs in the HoxA and HoxB clusters retain homology with amphioxus CNSs through the two-round whole genome duplications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981416"}
{"pmid": "20981417", "title": "Biochemistry of lactone formation in yeast and fungi and its utilisation for the production of flavour and fragrance compounds.", "content": "Biochemistry of lactone formation in yeast and fungi and its utilisation for the production of flavour and fragrance compounds. The consumers' demand for natural flavour and fragrances rises. To be natural, compounds have to result from the extraction of natural materials and/or to be transformed by natural means such as the use of enzymes or whole cells. Fungi are able to transform some fatty acids into lactones that can thus be natural. Although some parts of this subject have been reviewed several times, the present article proposes to review the different pathways utilised, the metabolic engineering strategies and some current concerns on the reactor application of the transformation including scaling up data. The main enzymatic steps are hydroxylation and β-oxidation in the traditional way, and lactone desaturation or Baeyer-Villiger oxidation. Although the pathway to produce γ-decalactone is rather well known, metabolic engineering strategies may result in significant improvements in the productivity. For the production of other lactones, a key step is the hydroxylation of fatty acids. Beside the biotransformation, increasing the production of the various lactones requires from biotechnologists to solve two main problems which are the toxicity of lactones toward the producing cell and the aeration of the emulsified reactor as the biochemical pathway is very sensitive to the level of available oxygen. The strategies employed to resolve these problems will be presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981417"}
{"pmid": "20981418", "title": "Understanding the effect of foreign gene dosage on the physiology of Pichia pastoris by transcriptional analysis of key genes.", "content": "Understanding the effect of foreign gene dosage on the physiology of Pichia pastoris by transcriptional analysis of key genes. Increased copy number of foreign gene can result in the alteration of normal metabolism in Pichia pastoris. To better understand the effect of foreign gene dosage on the cellular physiology of P. pastoris cells, comparative transcriptional analysis was performed among three P. pastoris strains carrying 0, 6, and 18 copies of porcine insulin precursor (PIP) expression cassettes, respectively. mRNA levels of 13 selected genes involved in methanol metabolic pathway, central metabolic pathway, protein folding, and oxidative stress were determined by real-time PCR. Results showed that enhanced PIP copy number resulted in an increase in PIP mRNA and also in folding stress on the yeast cells' endoplasmic reticulum. The metabolism of 6-copy P. pastoris strain was not significantly changed as compared to 0-copy strain (control). In contrast, physiology of 18-copy strain was remarkably affected, characterized by the upregulation of antioxidative genes and readjusted expression level of methanol metabolic pathway genes. These data suggested that high copy P. pastoris strain might be suffering from protein folding-related oxidative stress and insufficient supply of carbon and energy sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981418"}
{"pmid": "20981420", "title": "The accuracy of 64-slice MDCT for determining the perforation site of the gastrointestinal tract: ROC analysis.", "content": "The accuracy of 64-slice MDCT for determining the perforation site of the gastrointestinal tract: ROC analysis. This study was performed to evaluate the diagnostic performance of 64-slice multidetector-row computed tomography (MDCT) for preoperatively detecting the perforation site in patients with gastrointestinal (GI) tract perforations. A total of 49 patients with pathologically proven GI tract perforations, who had undergone MDCT were included in this study. The contrast-enhanced axial images (3 mm thick) and multiplanar reformation (MPR) images (3 mm thick) were generated for all the patients. Two radiologists independently reviewed the two sets of MDCT images (axial set: the axial images alone, and combined set: the axial and MPR images) for the detection of the perforation site. The perforation site was considered to be positive according to the direct and indirect findings. The diagnostic accuracy was assessed with a receiver operating characteristic (ROC) analysis. Weighted kappa statistics were used to evaluate the interobserver agreement. The corresponding values in respect of the first and the second observers for the areas under the ROC curve were 0.984 and 0.966 for the axial set; and 0.998 and 0.973 for the combined set. The differences were not statistically significant between the two data sets for each observer (P > 0.05). Both the observers detected the perforation site in 43 (87.8%) and 40 (81.6%) patients on the axial set, and in 46 (93.9%) and 41 (83.7%) patients on the combined set, respectively. The kappa values between the two observers showed excellent agreement with the two data sets. 64-slice MDCT showed a consistently excellent diagnostic performance for preoperatively determining the perforation site in patients with GI tract perforations, irrespective of the availability of the MPR images.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981420"}
{"pmid": "20981419", "title": "Biocatalytic properties of a recombinant aldo-keto reductase with broad substrate spectrum and excellent stereoselectivity.", "content": "Biocatalytic properties of a recombinant aldo-keto reductase with broad substrate spectrum and excellent stereoselectivity. In the screening of 11 E. coli strains overexpressing recombinant oxidoreductases from Bacillus sp. ECU0013, an NADPH-dependent aldo-keto reductase (YtbE) was identified with capability of producing chiral alcohols. The protein (YtbE) was overexpressed, purified to homogeneity, and characterized of biocatalytic properties. The purified enzyme exhibited the highest activity at 50°C and optimal pH at 6.5. YtbE served as a versatile reductase showing a broad substrate spectrum towards different aromatic ketones and keto esters. Furthermore, a variety of carbonyl substrates were asymmetrically reduced by the purified enzyme with an additionally coupled NADPH regeneration system. The reduction system exhibited excellent enantioselectivity (>99% ee) in the reduction of all the aromatic ketones and high to moderate enantioselectivity in the reduction of α- and β-keto esters. Among the ketones tested, ethyl 4,4,4-trifluoroacetoacetate was found to be reduced to ethyl (R)-4,4,4-trifluoro-3-hydroxy butanoate, an important pharmaceutical intermediate, in excellent optical purity. To the best of our knowledge, this is the first report of ytbE gene-encoding recombinant aldo-keto reductase from Bacillus sp. used as biocatalyst for stereoselective reduction of carbonyl compounds. This study provides a useful guidance for further application of this enzyme in the asymmetric synthesis of chiral alcohol enantiomers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981419"}
{"pmid": "20981422", "title": "Primary intraluminal leiomyosarcoma of the inferior vena cava: value of MRI with contrast-enhanced MR venography in diagnosis and treatment.", "content": "Primary intraluminal leiomyosarcoma of the inferior vena cava: value of MRI with contrast-enhanced MR venography in diagnosis and treatment. Primary intraluminal leiomyosarcoma of the inferior vena cava (IVC) is extremely rare. Diagnostic imaging plays an important role in the diagnosis and conducting treatment strategy. MRI with contrast-enhanced MR venography was performed in six patients with primary intraluminal leiomyosarcoma of the IVC. In the six patients, three had leiomyosarcoma of the middle IVC, and three the lower IVC. The mean axial diameter of tumor was 4.3 cm. MRI with contrast-enhanced MR venography not only demonstrated the tumor's location, morphology, extent, and collateral vessels but also distinguished tumor from thrombus of the IVC. Three patients underwent surgery and three did not. Four patients (three with surgery and one without surgery) were alive during the following periods, but one presented with local recurrence and all with metastases at a median time of 23 months. One patient died at 15 months after the diagnosis with liver and subcutaneous metastases, one lost to follow up. MR image with contrast-enhanced MR venography is a noninvasive and accurate technique for diagnosis of primary intraluminal leiomyosarcoma of IVC. Its providing information is very helpful for pre- and post-surgery. It can be used as one of the first choice examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981422"}
{"pmid": "20981421", "title": "Symptomatic spontaneous celiac artery dissection treated by conservative management: serial imaging findings.", "content": "Symptomatic spontaneous celiac artery dissection treated by conservative management: serial imaging findings. The aim of this study was to evaluate the correlation of clinical characteristics with serial imaging findings of symptomatic spontaneous celiac artery dissection treated by conservative management. Eight consecutive, hemodynamically stable patients with symptomatic spontaneous celiac artery dissection without associated aortic dissection that received non-operative treatments were included in this study. Their clinical characteristics, treatment methods, serial imaging findings and outcomes were analyzed retrospectively. Acute left flank pain related to splenic infarction was the most common clinical manifestation. Initial contrast-enhanced dynamic computed tomography scan showed celiac artery dissection with partial thrombosis in all eight patients and involvement of branch vessels in 7. Full anticoagulation was carried out immediately after the diagnosis in seven patients. All patients, except one with endovascular stent placement, were asymptomatic after successful conservative management and follow-up computed tomography scan showed preservation of distal perfusion with ongoing regression of false lumen in five patients. After a mean follow-up of 16 months, there was no mortality or morbidity related to the dissection. Serial imaging findings showed that conservative management of celiac artery dissection can be performed successfully in selective patients with stable hemodynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981421"}
{"pmid": "20981423", "title": "CT virtual endoscopy of the ampulla of Vater: preliminary report.", "content": "CT virtual endoscopy of the ampulla of Vater: preliminary report. To explore multi-slice spiral CT (MSCT) virtual endoscopy (CTVE) in the detection of Vater's ampulla lesions. In addition to 30 healthy volunteers, 18 cases of common bile duct stones, and 7 cases of ampullary carcinoma were scanned with MSCT including virtual endoscopy (VE) reconstruction. Patterns of the duodenal papilla were then observed, and its size was measured. Reconstructed images of CTVE in the volunteers showed that the normal type of the duodenal papilla was nodular in 16 cases, V-shaped in 8 cases, and Y-shaped in 6 cases. Its mean diameter was 0.84 ± 0.17 cm in the healthy volunteers; in patients with common bile duct stones of nodular type, mean diameter was 1.72 ± 0.32 cm. In ampullary cancer patients with an irregular protruded type, its diameter was 2.30 ± 0.85 cm, Overall the mean differences between the groups were statistically significant (P < 0.001). CTVE is a convenience, no-wound, and precise clinical examination mode utilizing which the shape of duodenal papilla can be observed, and size of the latter can be measured.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981423"}
{"pmid": "20981424", "title": "Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors.", "content": "Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors. With the aim to identify cyclin B1-derived peptides with high affinity for HLA-A2, we used three in silico prediction algorithms to screen the protein sequence for possible HLA-A2 binders. One peptide scored highest in all three algorithms, and the high HLA-A2-binding affinity of this peptide was verified in an HLA stabilization assay. By stimulation with peptide-loaded dendritic cells a CTL clone was established, which was able to kill two breast cancer cell lines in an HLA-A2-dependent and peptide-specific manner, demonstrating presentation of the peptide on the surface of cancer cells. Furthermore, blood from cancer patients and healthy donors was screened for spontaneous T-cell reactivity against the peptide in IFN-γ ELISPOT assays. Patients with breast cancer, malignant melanoma, or renal cell carcinoma hosted powerful and high-frequency T-cell responses against the peptide. In addition, when blood from healthy donors was tested, similar responses were observed. Ultimately, serum from cancer patients and healthy donors was analyzed for anti-cyclin B1 antibodies. Humoral responses against cyclin B1 were frequently detected in both cancer patients and healthy donors. In conclusion, a high-affinity cyclin B1-derived HLA-A2-restricted CTL epitope was identified, which was presented on the cell surface of cancer cells, and elicited spontaneous T-cell responses in cancer patients and healthy donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981424"}
{"pmid": "20981425", "title": "CIRSE vascular closure device registry.", "content": "CIRSE vascular closure device registry. Vascular closure devices are routinely used after many vascular interventional radiology procedures. However, there have been no major multicenter studies to assess the safety and effectiveness of the routine use of closure devices in interventional radiology. The CIRSE registry of closure devices with an anchor and a plug started in January 2009 and ended in August 2009. A total of 1,107 patients were included in the registry. Deployment success was 97.2%. Deployment failure specified to access type was 8.8% [95% confidence interval (95% CI) 5.0-14.5] for antegrade access and 1.8% (95% CI 1.1-2.9) for retrograde access (P = 0.001). There was no difference in deployment failure related to local PVD at the access site. Calcification was a reason for deployment failure in only <0.5% of patients. Postdeployment bleeding occurred in 6.4%, and most these (51.5%) could be managed with light manual compression. During follow-up, other device-related complications were reported in 1.3%: seven false aneurysms, three hematoma >5.9 cm, and two vessel occlusions. The conclusion of this registry of closure devices with an anchor and a plug is that the use of this device in interventional radiology procedures is safe, with a low incidence of serious access site complications. There seems to be no difference in complications between antegrade and retrograde access and other parameters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981425"}
{"pmid": "20981426", "title": "Circulating procoagulant microparticles in cancer patients.", "content": "Circulating procoagulant microparticles in cancer patients. Accumulating evidence indicates that microparticles (MPs) are important mediators of the interaction between cancer and the hemostatic system. We conducted a large prospective cohort study to determine whether the number of circulating procoagulant MPs is elevated in cancer patients and whether the elevated MP levels are predictive of occurrence of venous thrombembolism (VTE). We analyzed plasma samples of 728 cancer patients from the ongoing prospective observational Vienna Cancer and Thrombosis Study. Study endpoint was the occurrence of symptomatic VTE. Sixty-five age- and sex-matched healthy controls were recruited for defining the cut-off point for elevated MPs (4.62 nanomolar phosphatidylserine [nM PS]), which was set at the 95th percentile of MP levels in healthy controls. The measurement of MPs was performed after capture onto immobilized annexin V, and determination of their procoagulant activity was quantified with a prothrombinase assay. During a median observation period of 710 days, 53 patients developed VTE. MP levels (nM PS) were significantly higher in cancer patients than in healthy controls (median [25th-75th percentile], 3.95 [1.74-7.96] vs. 1.19 [0.81-1.67], p<0.001). Multivariate analysis including age, sex, surgery, chemo- and radiotherapy showed no statistically significant association of the hazard ratio of elevated MPs with VTE (0.95 [95% CI, 0.55-1.64], p=0.856). In conclusion, MP levels were elevated in cancer patients compared to healthy individuals in this study. However, elevated MP levels were not predictive of VTE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981426"}
{"pmid": "20981427", "title": "Household epidemic models with varying infection response.", "content": "Household epidemic models with varying infection response. This paper is concerned with SIR (susceptible → infected → removed) household epidemic models in which the infection response may be either mild or severe, with the type of response also affecting the infectiousness of an individual. Two different models are analysed. In the first model, the infection status of an individual is predetermined, perhaps due to partial immunity, and in the second, the infection status of an individual depends on the infection status of its infector and on whether the individual was infected by a within- or between-household contact. The first scenario may be modelled using a multitype household epidemic model, and the second scenario by a model we denote by the infector-dependent-severity household epidemic model. Large population results of the two models are derived, with the focus being on the distribution of the total numbers of mild and severe cases in a typical household, of any given size, in the event that the epidemic becomes established. The aim of the paper is to investigate whether it is possible to determine which of the two underlying explanations is causing the varying response when given final size household outbreak data containing mild and severe cases. We conduct numerical studies which show that, given data on sufficiently many households, it is generally possible to discriminate between the two models by comparing the Kullback-Leibler divergence for the two fitted models to these data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981427"}
{"pmid": "20981428", "title": "Investigation of the veins in patients with Behçet's disease with no known vascular event by Doppler ultrasonography.", "content": "Investigation of the veins in patients with Behçet's disease with no known vascular event by Doppler ultrasonography. In Behçet's disease, deep venous thrombosis occurs primarily in the lower extremities. Total recanalization rate is low, so thrombotic segment could be detected by imaging afterward. For disclosing vein involvement, leg swelling is commonly queried in the history taking in those patients. However, there are no data about the presence of \"silent\" thrombosis in patients with BD. We aimed at investigating the integrity of venous vessels in BD, without any known vascular event by using Doppler ultrasonography (DU). Patients having past events revealed in the vascular questionnaire or physical findings attributable to vascular disease were excluded. Various degree of venous insufficiency was detected in 74 patients in BD (74%), 24 out of 33 patients (72%) in AS and in 8 out of 34 (25%) in HC group. All were at the lower extremities, and there is no difference in the frequency between BD and AS, while both were significantly higher than in HC (P = 0.001, and 0.004, respectively). Six patients with BD (6%) have chronic venous thrombi at the lower extremities and none in either AS and HC. As a non-invasive method, DU of lower extremities may disclose \"silent\" thrombosis. Venous insufficiency in those patients should be considered cautiously as an indicator of vein involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981428"}
{"pmid": "20981431", "title": "Ficus deltoidea (Mas cotek) extract exerted anti-melanogenic activity by preventing tyrosinase activity in vitro and by suppressing tyrosinase gene expression in B16F1 melanoma cells.", "content": "Ficus deltoidea (Mas cotek) extract exerted anti-melanogenic activity by preventing tyrosinase activity in vitro and by suppressing tyrosinase gene expression in B16F1 melanoma cells. Ficus deltoidea (Mas cotek) water extract has been widely used for woman health in Malaysia. Our investigation focused to identify anti-melanogenic efficacy of F. deltoidea since it has been known to have strong anti-oxidant activities. Anti-melanogenic effect of F. deltoidea extract was analyzed using cultured B16F1 melanoma cells. Cytotoxicity of the extract was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and determined the highest concentration of the extract that did not affect cell viability as 0.1% (w/v). α-MSH-induced melanin synthesis was significantly inhibited with dose-dependent manner by treatment of F. deltoidea leave extract, which was comparable to that of kojic acid. The extract directly inhibited mushroom tyrosinase activity and intracellular tyrosinase activity of B16F1 as well. The inhibition of intracellular tyrosinase activity was found to be exerted at the protein expression level when analyzed by immunoblot and tyrosinase zymography. The expression of microphthalmia-associated transcription factor (MITF) was also reduced by the F. deltoidea extract. In conclusion, F. deltoidea extract has strong anti-melanogenic activity that is exerted by direct inhibition of tyrosinase enzyme activity and by down-regulation of the expression of genes involved in the melanogenesis pathways. Collectively, data shown in this study strongly suggest that F. deltoidea extract has potential to be used as a novel depigmenting agent for cosmetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981431"}
{"pmid": "20981430", "title": "Right ventricular function in grown-up patients after correction of congenital right heart disease.", "content": "Right ventricular function in grown-up patients after correction of congenital right heart disease. We investigated whether a correlation exists between biomarkers of the neurohumoral system and clinical markers in grown-up patients with congenital heart disease (GUCH) and right ventricular function. Prospective, cross-sectional, multicenter study of 104 GUCH patients (median) 16 years (range 6-43 years) after corrective surgery with RV pressure and/or volume overload and 54 healthy controls. Clinical, functional, and laboratory parameters were assessed. Natriuretic peptide levels were significantly increased in GUCH patients (NTproBNP 101 vs. 25 pg/ml, p < 0.001), but we observed no differences in norepinephrine, aldosterone, angiotensin II and Endothelin-1 levels. NTproBNP correlated significantly with clinical markers such as NYHA classification, prolonged QRS duration and reduced exercise capacity (VO(2) peak) (all p < 0.001), as well as self-reported quality of life (p < 0.001). MRI and echocardiography derived RV volumes were elevated and ejection fraction reduced in the patients (both p < 0.001). Tissue Doppler parameter showed significantly restricted ventricular longitudinal systolic function (longitudinal tricuspid valve movement, 1.7 vs. 2.3 cm, p < 0.001), suggesting stiffness and reduced RV compliance. In conclusion, grown-up patients with congenital right heart disease NTproBNP correlates well with various clinical markers of RV failure, such as prolongation of QRS duration, exercise capacity, echocardiography and MRI parameters, and quality of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981430"}
{"pmid": "20981433", "title": "Iron status parameters in preeclamptic women.", "content": "Iron status parameters in preeclamptic women. Evidence of increased oxidative stress due to endothelial dysfunction in preeclampsia has been well established. Increase in the oxidative stress is catalyzed in the presence of free transitional metals. Therefore, the relationship of iron status with preeclampsia was under investigation. The objective of the study was to compare red blood cell (RBC) count, hemoglobin (Hb) concentration, hematocrit (Hct), RBC indices, and iron status parameters in preeclamptic and healthy pregnant women. Blood samples were collected from 40 pregnant females diagnosed as preeclampsia and 80 normal pregnant females at the Department of Obstetrics and Gynecology at King Abdulaziz Medical City, Riyadh, Saudi Arabia between February 2009 and January 2010. We recorded RBC count, Hb concentration, Hct, RBC indices, serum iron and ferritin levels in both the groups. Mean serum iron in preeclampsia group was 23.48 ± 9.05, while 12.2 ± 5.21 in normal group (p <0.05). Similarly, mean serum ferritin concentration in preeclamptic and normal pregnant women were 32.56 ± 11.72 and 19.89 ± 8.86, respectively (p < 0.05). No significant differences were found among RBC count, Hb concentration, Hct, and RBC indices in both the groups. We recommend that any pregnant female with higher serum iron and ferritin concentrations should be further investigated for preeclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981433"}
{"pmid": "20981434", "title": "Repeatability of intra-ocular pressure and central corneal thickness measurements provided by a non-contact method of tonometry and pachymetry.", "content": "Repeatability of intra-ocular pressure and central corneal thickness measurements provided by a non-contact method of tonometry and pachymetry. To examine the repeatability of intra-ocular pressure (IOP) and central corneal thickness (CCT) measurements provided by the Tono-Pachymeter NT530P (Nidek, Japan), and to assess agreement of the device with Goldmann applanation tonometry (GAT) and ultrasound pachymetry (UP). Sixty-two normal eyes of 62 subjects were included in the study. Three sessions of measurements, each consisting of three sets of measurements, were completed with each device. Repeatability was determined with the coefficient of variation (CoV) and the coefficient of repeatability (CoR) values. Agreement between devices was examined by Bland-Altman analysis and intraclass correlation coefficient (ICC) analyses. The CoV and CoR for IOP values were 18.4% and 5.5 mmHg with the NT530P and 16.6% and 4.3 mmHg with the GAT respectively. On average, NT530P overestimated the IOP compared with GAT by 1.3 mmHg. The 95% limits of agreement between the methods ranged from -5.9 to +3.3 mmHg, and the ICC for average IOP measures between devices was 0.64 (P < 0.001). The CoV and CoR for CCT measurements were 5.5% and 59.8 μm with the NT530P and 5.5% and 60.5 μm with UP. NT530P CCT readings were on average 13 μm thinner than those obtained with UP. The 95% limits of agreement (LoA) ranged from -7.4 to +33.1 μm, and the ICC for average CCT measures between devices was 0.93 (P < 0.001). The NT530P demonstrated high IOP and CCT measurement repeatability in the normal population studied. The device tended to slightly overestimate IOP compared to GAT. CCT values provided by NT530P were interchangeable with those of UP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981434"}
{"pmid": "20981435", "title": "Intraobserver and interobserver repeatability of ocular components measurement in cataract eyes using a new optical low coherence reflectometer.", "content": "Intraobserver and interobserver repeatability of ocular components measurement in cataract eyes using a new optical low coherence reflectometer. The purpose of the study was to assess intraobserver and interobserver repeatability of eight ocular components measurement in cataract eyes using the optical low-coherence reflectometer Lenstar LS 900®. Five consecutive measurements of ocular components were taken by two examiners using the Lenstar. Components analyzed were: central corneal thickness, lens thickness, anterior chamber depth, axial length, retinal thickness, keratometry, white-to-white distance, and pupillometry. Within-subject standard deviation and the coefficient of variation were calculated for evaluation of intraobserver repeatability. Bland-Altman analysis was used for assessment of interobserver repeatability. Thirty-two eyes of 22 patients were included. For both observers, the smallest intraobserver coefficient of variation was obtained for axial length, while the largest was found for corneal steepest meridian position. Interobserver repeatability demonstrated less repeatable results for white-to-white distance and corneal steepest meridian position. Considering axial length and anterior chamber depth values, predicted refractive error was 0 ± 0.05 D and 0.02 ± 0.19 D respectively in 95% of observations. The Lenstar LS 900® evidenced excellent repeatability and observers´ independent results of all components analyzed except white-to-white distance and corneal steepest meridian position measurements. To the best of our knowledge, this is the first study on interobserver repeatability of optical low-coherence reflectometry in cataract eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981435"}
{"pmid": "20981436", "title": "Predictors of maximal short-term power outputs in basketball players 14-16 years.", "content": "Predictors of maximal short-term power outputs in basketball players 14-16 years. Relationships between growth, maturation and maximal short-term power outputs were investigated in 94 youth basketball players aged 14-16 years. Data included chronological age (CA), skeletal age (SA), years of training; body dimensions, estimated thigh volume, a running based short-term exercise assessed by the line drill test (LDT), the Bangsbo sprint test (BST) and short-term muscle power outputs with the Wingate anaerobic test (WAnT). Multiple linear regression analyses were used to estimate the effects of CA, skeletal maturity (SA/CA), years of training experience, body size and lower-limb volume on short-term performance in the LDT, BST and WAnT, respectively. Explained variances differed between cycle-ergometry outputs (52-54%) and running test performances (23-46%). The independent effects of predictors were small in the fatigue scores of the WAnT (4%) and the BST (11%). Skeletal maturity, body mass and leg length were primary predictors for all maximal short-term power output measures. Leg length was more relevant as a predictor than stature in the WAnT outputs, while stature and body mass appeared in the model with the running tests as dependent variable. Maximal short-term running abilities were also sensitive to years of training. In summary, skeletal maturation, body size and thigh muscle mass explained moderate to large proportions of the variance on maximal short-term performances of adolescent basketball players. The results highlight the importance of considering maturity status in evaluating the maximal short-term power outputs of adolescent athletes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981436"}
{"pmid": "20981437", "title": "Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel.", "content": "Lidocaine partially depolarizes the S4 segment in domain IV of the sodium channel. Previous studies have shown that lidocaine and other local anesthetic drugs (LAs) cause use-dependent block of sodium current (I (Na)), i.e., block that increases with membrane depolarization by allosteric coupling between drug binding in the inner pore and the S4s in domains III and IV. MTSET protection experiments have established that LAs stabilize DIIIS4 in an outward, depolarized position. Similar tests have not been reported for the DIVS4, although LAs have been shown to reduce DIV's contribution to total gating charge by about one third and to alter its movement such that it contributes more gating charge at negative potentials around -100 mV compared to non-drug-bound sodium (Na) channels. To investigate whether lidocaine reduces the gating charge of DIVS4 by causing it to adopt either a depolarized position at rest or by restricting its outward movement upon depolarization, we performed MTSET protection experiments on I (Na) of the mutant Na channel, R1628C (R3C-DIV), in the presence and absence of 10 mM lidocaine. The results indicate that lidocaine causes the DIVS4 to assume a more depolarized position, which facilitates its movement upon depolarization leading to the excess gating charge at potentials near -100 mV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981437"}
{"pmid": "20981438", "title": "Perceiving performer identity and intended expression intensity in point-light displays of dance.", "content": "Perceiving performer identity and intended expression intensity in point-light displays of dance. This study investigated agent and expression intensity recognition in point-light displays depicting dancing performances. In a first session, participants danced with two different expression intensities to music, solo or in dyads. In a subsequent session, they watched point-light displays of 1-5-s duration, depicting their own, their partner's or another participant's recorded actions, and were asked to identify the agent (self vs. partner vs. stranger) and the intended expression intensity (expressive vs. inexpressive) of the performer. The results indicate that performer identity and expression intensity could be discerned reliably from displays as short as 1 s. The accuracy in judgment increased with exposure duration and, for performer identification, with higher expression intensity. Judgment accuracy in agent and expression intensity recognition tasks correlated with self-report empathy indices. Accuracy correlated also with confidence in judgment, but only in the intensity recognition task. The results are discussed in relation to perceptual and neural mechanisms underlying action and intention recognition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981438"}
{"pmid": "20981439", "title": "Chromosome 3p alterations in pancreatic endocrine neoplasia.", "content": "Chromosome 3p alterations in pancreatic endocrine neoplasia. Pancreatic endocrine tumors (PET) are rare neoplasms classified as functioning (F-PET) or non-functioning (NF-PET) according to the presence of a clinical syndrome due to hormonal hypersecretion. PETs show variable degrees of clinical aggressiveness and loss of chromosome 3p has been suggested to be associated with an advanced stage of disease. We assessed chromosome 3p copy number in 113 primary PETs and 32 metastases by fluorescence in situ hybridization (FISH) using tissue microarrays. The series included 56 well-differentiated endocrine tumors (WDET), 62 well-differentiated endocrine carcinomas (WDEC), and 6 poorly differentiated endocrine carcinomas (PDEC). Chromosome 3p alterations were found in 23/113 (20%) primary tumors, with losses being predominant over gains (14% vs. 6%). Loss of 3p was found in 5/55 (9%) WDET, 11/52 (21%) WDEC, and never in PDEC. Gains of 3p were detected in 4/55 (7%) WDET, no WDEC, but notably in 3/6 (50%) PDEC (OR 23.6; P = 0.003). Metastases were more frequently monosomic for 3p compared to primary tumors (OR 3.6; P = 0.005). Monosomy was significantly associated with larger tumor size, more advanced tumor stage, and metastasis. No association was found with survival. Chromosome 3p copy number alterations are frequent events in advanced stage PET, with gains prevailing in PDEC while losses are more frequent in WDEC, supporting the view that a specific pattern of alterations are involved in these diverse disease subtypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981439"}
{"pmid": "20981441", "title": "Clinical characteristics of children with group A streptococcal toxic shock syndrome admitted to pediatric intensive care units.", "content": "Clinical characteristics of children with group A streptococcal toxic shock syndrome admitted to pediatric intensive care units. Streptococcal toxic shock syndrome (STSS) is a very rare and severe form of group A streptococcal infection whose clinical characteristics, therapy, morbidity, and mortality in children are not well known. Our objective was to describe the clinical characteristics of STSS in a series of children admitted to pediatric intensive care units (PICU). A multicenter, retrospective study of children with STSS admitted to 14 PICUs between January 1998 and December 2009 was conducted. Clinical information was obtained retrospectively by chart review. Data from 41 children were collected, 90% corresponding to the second half of the study period. Initial symptoms and signs were nonspecific. All patients developed shock and organ dysfunction, 78.0% developed coagulopathy, 70.7% neurologic dysfunction, and 68.3% respiratory failure. Rapid pharyngeal test for Streptococcus was positive in 78.0%. Initial leukocyte count was quite variable, with leukopenia present in 51.2% of patients and leukocytosis in 31.7%. Children were treated with antibiotics against group A Streptococcus (GAS), usually G penicillin or cephalosporin plus clindamycin. After a median PICU stay of 7 days (range 0-41), 65.8% of patients survived, 26.8% with sequelae. The cause of death of the 11 non-survivors was refractory shock and multi-organ failure. STSS is a very severe condition secondary to invasive GAS infection. It can occur at any age, but especially in young children. Due to the lack of specific symptoms and signs and its very rapid progression to shock and organ dysfunction, pediatricians and emergency physicians must be aware of this possibility and immediately initiate aggressive treatment when suspected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981441"}
{"pmid": "20981440", "title": "Maternal active or passive smoking causes oxidative stress in placental tissue.", "content": "Maternal active or passive smoking causes oxidative stress in placental tissue. The aim of this study was to assess the influence of active and passive maternal smoking on placenta total oxidant/antioxidant status in term infants. The levels of cord blood total antioxidant capacity (TAC), total oxidant status (TOS), and oxidative stress index (OSI) were measured in samples of fetal placental tissue, cord blood, and the maternal peripheral blood serum and from 19 mothers who were active smokers, 19 who were passive smokers, and 22 who were nonsmokers (not exposed to active or passive smoking). The pregnancies were between 37 and 40 weeks' gestation, were uncomplicated, and the infants were delivered vaginally. Birth weight and head circumference in the active smokers were significantly (P < 0.001) lower than those in the controls. Placenta, cord blood, and the maternal peripheral TAC levels were significantly lower in the active smokers compared with the controls (P < 0.001), while TOS and OSI levels were significantly higher in the active and passive smokers than in the controls (P < 0.001). A positive significant correlation was found between active maternal smoking and placenta TOS and OSI levels (P < 0.016), and a significant negative correlation was found between number of cigarettes exposed to and birthweight and head circumference (P < 0.05). In conclusion, active or passive maternal smoking is associated with important alterations in oxidant and antioxidant balance in fetal placental tissue and causes potent oxidative stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981440"}
{"pmid": "20981442", "title": "Comparative karyological analysis of four diplozoid species (Monogenea, Diplozoidae), gill parasites of cyprinid fishes.", "content": "Comparative karyological analysis of four diplozoid species (Monogenea, Diplozoidae), gill parasites of cyprinid fishes. The present study has revealed new data on chromosome complements of diplozoid parasites, namely Diplozoon paradoxum from freshwater bream Abramis brama, Paradiplozoon bliccae from white bream Blicca bjoerkna, Paradiplozoon sapae from white-eye bream Ballerus sapa, and Paradiplozoon nagibinae from zope Ballerus ballerus. Particularly, D. paradoxum is characterized by four pairs (2n=8) of long (up to 22.1 μm) chromosomes: pairs 1, 2, and 3 are metacentric and pair 4 acrocentric. Karyotypes of three Paradiplozoon species are nearly identical in number and morphological classification of chromosomes, each comprising diploid number of 14 one-armed chromosomes of very similar length ranging up to 12.5 μm in P. bliccae, 9.2 μm in P. sapae, and 9.9 μm in P. nagibinae. All four species are similar in their total complement length, ranging from 64.4 to 50.4 μm. Interspecific differences were found in location of secondary constriction: it is situated on short arm of the 1st chromosome pair in D. paradoxum, on long arm of the 7th pair in P. bliccae and on long arm of the 4th pairs in P. sapae and P. nagibinae. Phylogenetic interrelationship within the diplozoids and hypothetic karyotype evolution is here discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981442"}
{"pmid": "20981443", "title": "Participation of metanauplii and juvenile individuals of Artemia parthenogenetica (Branchiopoda) in the circulation of avian cestodes.", "content": "Participation of metanauplii and juvenile individuals of Artemia parthenogenetica (Branchiopoda) in the circulation of avian cestodes. Adult crustaceans of the genus Artemia (brine shrimps) are intermediate hosts in the life cycle of cestode species parasitic in aquatic birds as their definitive hosts. However, there are no data on the role of larval and juvenile brine shrimps in the transmission of avian helminth parasites. In order to examine the possible role of early developmental stages (nauplii, metanauplii and juveniles) of Artemia for the circulation of avian cestodes, the natural cestode infection in the population of Artemia parthenogenetica from La Mata Lagoon, Mediterranean coast of Spain, was studied. Metacestodes (cysticercoids) of four cestode species were recorded in adult brine shrimps: Flamingolepis liguloides and Flamingolepis flamingo (hymenolepidids parasitic in flamingos), Confluaria podicipina (a hymenolepidid species parasitic in grebes) and Eurycestus avoceti (a dilepidid species parasitic in avocets, stilts, plovers and, to a lesser extent, in flamingos). No cysticercoids were found in nauplii. Two species, F. liguloides and F. flamingo, were found in metanauplii and juvenile brine shrimps. Only 36.3% of the cysticercoids of F. liguloides occurred in adult brine shrimps; the remaining 63.7% were parasitic in metanauplii (39.6%) and juveniles (24.1%). Similarly, the metacestodes of F. flamingo were also distributed among various age groups: in adults (44.4% of cysticercoids), juveniles (27.8%) and metanauplii (27.8%). These results indicate that the early developmental stages of Artemia have an important role for the circulation of certain parasite species. No cysticercoids of C. podicipina and E. avoceti were recorded in larval and juvenile brine shrimps. The selective infestation of larval brine shrimps with flamingo parasites is probably associated with the feeding behaviour of definitive hosts, which are filtering predators; in contrast, grebes and waders pick brine shrimps individually one by one. The possible underlying mechanism for selective infestation of metanauplii and adults by certain cestode species is associated with the size of parasite eggs, allowing only cestode species with small eggs to be ingested by larval brine shrimps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981443"}
{"pmid": "20981444", "title": "Ultrastructure of the spermatozoon of Taeniarhynchus saginatus (syn. Taenia saginata) (Goeze, 1782) Weinland, 1858 (Cestoda, Taeniidae) an intestinal parasite of human.", "content": "Ultrastructure of the spermatozoon of Taeniarhynchus saginatus (syn. Taenia saginata) (Goeze, 1782) Weinland, 1858 (Cestoda, Taeniidae) an intestinal parasite of human. The mature Taeniarhynchus saginatus spermatozoon exhibits an apical cone of electron-dense material and one helicoidal crest-like body roughly 50 nm thick. The axoneme is of the 9 + \"1\" Trepaxonemata pattern. It is surrounded by a periaxonemal sheath of electron-dense material. The cytoplasm is electron lucent and divided into compartments by intracytoplasmic walls of electron-dense material in regions III and IV. The nucleus is an electron-dense cord 60-90 nm thick coiled in a spiral around the axoneme. It reaches the posterior extremity of the gamete where the axoneme is disorganized and is accompanied on all its posterior length by the nucleus. To our knowledge, such a posterior extremity has never been described before in a cyclophyllidean cestode.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981444"}
{"pmid": "20981445", "title": "A cysteine proteinase in the penetration glands of the cercariae of Cotylurus cornutus (Trematoda, Strigeidae).", "content": "A cysteine proteinase in the penetration glands of the cercariae of Cotylurus cornutus (Trematoda, Strigeidae). A cysteine proteinase from the penetration glands of Cotylurus cornutus cercariae was examined with histochemical and biochemical methods. The enzyme hydrolyzed gelatin, azocoll, azocasein, azoalbumin, N-blocked-L-arginine-4-methoxy-2-naphthylamide, and N-blocked-p-nitroanilide, but did not degrade elastin. The metal ion complexane ethylenediamine tetraacetate and the thiol-reducing compound dithioerythritol enhanced the proteinase activity, whereas the thiol-blocking compounds p-hydroxymercuribenzoate and N-ethylmaleimide (NEM) inhibited it. The enzyme was also sensitive to leupeptin but insensitive to soybean trypsin inhibitor. An electrophoretic separation of extract proteins from the cercariae under acidic, non-denaturing conditions and in the presence of 0.1% gelatin in a polyacrylamide gel revealed the presence of two distinct and three weak transparent bands in the gel resulting from a gelatinolytic activity at pH 6.8. The distinct bands apparently resulted from the activity of the glandular enzyme and lysosomal cathepsin B, whereas the weak ones presumably indicated these enzymes partially degraded in the course of the preparative procedure. No gelatinolysis occurred following treatment of an extract sample with 0.1 mM NEM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981445"}
{"pmid": "20981446", "title": "Helminth parasites of freshwater fish in Chiapas, Mexico.", "content": "Helminth parasites of freshwater fish in Chiapas, Mexico. An inventory based on previously published records and original data is presented for the helminth parasites reported in 54 fish species from 17 families from the state of Chiapas, southeast Mexico. This survey reports the presence of 43 helminth species in Chiapas for the first time. The actualized inventory of helminth parasites of freshwater fish from Chiapas contains 88 species from 67 genera and 40 helminth families. Trematodes and nematodes were the most abundant taxonomic groups. The helminth fauna in freshwater fishes from Chiapas consists of Central American species. All the helminth species recorded in Chiapas have also been collected from bodies of freshwater between the Isthmus of Tehuantepec and the Isthmus of Panama. This inventory shows that this fauna is quite similar to that from the neighboring basins of the lower Grijalva-Usumacinta system and the Yucatan Peninsula. The taxonomic composition and distribution data reported here for the helminth fauna of Chiapas' freshwater fish, contribute to a better understanding of this faunal component in Central America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981446"}
{"pmid": "20981447", "title": "Molecular cloning of two novel mucin-like genes in the disease-susceptibility locus for diffuse panbronchiolitis.", "content": "Molecular cloning of two novel mucin-like genes in the disease-susceptibility locus for diffuse panbronchiolitis. Diffuse panbronchiolitis (DPB) is a rare complex genetic disease affecting East Asians and is strongly associated with the class I human leukocyte antigens (HLA)-B54 in Japanese and HLA-A11 in Koreans. We recently showed that an HLA-associated major susceptibility gene for DPB is probably located within the 200 kb in the class I region 300 kb telomeric of the HLA-B locus on the chromosome 6p21.3. We cloned two novel mucin-like genes designated panbronchiolitis related mucin-like 1 and 2 (PBMUCL1 and PBMUCL2) in the candidate region, which form a mucin-like gene cluster together with two adjacent genes, MUC21 and DPCR1. PBMUCL1 gene expression was remarkably upregulated by polyinosine-polycytidylic acid [poly(I:C)] stimulation in normal human bronchial epithelial cells redifferentiated at the air-liquid interface. We found genetic polymorphisms in PBMUCL1 gene which were associated with DPB: the A-allele of the PBMUCL1 intron 2 single nucleotide polymorphism (SNP) was positively associated and variable numbers of tandem repeats (VNTR) polymorphism in exon 3 (1,890-base pair deletion) was negatively associated. Despite a strong association with HLA-B in the Japanese, the mucin-like gene PBMUCL1 is also one of the candidate genes of DPB susceptibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981447"}
{"pmid": "20981448", "title": "A novel survival multifactor dimensionality reduction method for detecting gene-gene interactions with application to bladder cancer prognosis.", "content": "A novel survival multifactor dimensionality reduction method for detecting gene-gene interactions with application to bladder cancer prognosis. The widespread use of high-throughput methods of single nucleotide polymorphism (SNP) genotyping has created a number of computational and statistical challenges. The problem of identifying SNP-SNP interactions in case-control studies has been studied extensively, and a number of new techniques have been developed. Little progress has been made, however, in the analysis of SNP-SNP interactions in relation to time-to-event data, such as patient survival time or time to cancer relapse. We present an extension of the two class multifactor dimensionality reduction (MDR) algorithm that enables detection and characterization of epistatic SNP-SNP interactions in the context of survival analysis. The proposed Survival MDR (Surv-MDR) method handles survival data by modifying MDR's constructive induction algorithm to use the log-rank test. Surv-MDR replaces balanced accuracy with log-rank test statistics as the score to determine the best models. We simulated datasets with a survival outcome related to two loci in the absence of any marginal effects. We compared Surv-MDR with Cox-regression for their ability to identify the true predictive loci in these simulated data. We also used this simulation to construct the empirical distribution of Surv-MDR's testing score. We then applied Surv-MDR to genetic data from a population-based epidemiologic study to find prognostic markers of survival time following a bladder cancer diagnosis. We identified several two-loci SNP combinations that have strong associations with patients' survival outcome. Surv-MDR is capable of detecting interaction models with weak main effects. These epistatic models tend to be dropped by traditional Cox regression approaches to evaluating interactions. With improved efficiency to handle genome wide datasets, Surv-MDR will play an important role in a research strategy that embraces the complexity of the genotype-phenotype mapping relationship since epistatic interactions are an important component of the genetic basis of disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981448"}
{"pmid": "20981449", "title": "Genome-wide analysis of copy number variants in age-related macular degeneration.", "content": "Genome-wide analysis of copy number variants in age-related macular degeneration. Age-related macular degeneration (AMD) is a complex genetic disease, with many loci demonstrating appreciable attributable disease risk. Despite significant progress toward understanding the genetic and environmental etiology of AMD, identification of additional risk factors is necessary to fully appreciate and treat AMD pathology. In this study, we investigated copy number variants (CNVs) as potential AMD risk variants in a cohort of 400 AMD patients and 500 AMD-free controls ascertained at the University of Iowa. We used three publicly available copy number programs to analyze signal intensity data from Affymetrix GeneChip SNP Microarrays. CNVs were ranked based on prevalence in the disease cohort and absence from the control group; high interest CNVs were subsequently confirmed by qPCR. While we did not observe a single-locus \"risk CNV\" that could account for a major fraction of AMD, we identified several rare and overlapping CNVs containing or flanking compelling candidate genes such as NPHP1 and EFEMP1. These and other candidate genes highlighted by this study deserve further scrutiny as sources of genetic risk for AMD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981449"}
{"pmid": "20981450", "title": "Mechanisms for phenotypic variation in Lesch-Nyhan disease and its variants.", "content": "Mechanisms for phenotypic variation in Lesch-Nyhan disease and its variants. Lesch-Nyhan disease is a neurogenetic disorder caused by mutation of the HPRT1 gene on the X chromosome. There is significant variation in the clinical phenotype, with more than 300 different known mutations. There are few studies that have addressed whether similar mutations result in similar phenotypes across different patients because hypoxanthine-guanine phosphoribosyltransferase (HGprt) deficiency is rare, and most mutations are unique or limited to individual families. However, recent studies have revealed multiple unrelated patients with similar mutations, providing an opportunity to examine genotype-phenotype correlations. We found significant variation among the clinical features of 10 patients from 8 unrelated families all carrying a mutation replacing guanine with adenine at base position 143 (c.143G>A) in the HPRT1 gene. This mutation results in replacement of arginine by histidine at amino acid position 48 (p.arg48his) in the HGprt enzyme. Biochemically, the enzyme exhibits reduced thermal integrity, a mechanism that may explain clinical variation. The literature reveals similar clinical variation among other patients with similar mutations, although the variation is relatively minor across the whole population of patients. Identifiable sources of clinical variation include known limitations of clinical ascertainment and mechanisms that affect residual enzyme activity and stability. These results are helpful for understanding genotype-phenotype correlations and discordance and likely are applicable to other neurogenetic disorders where similar variation occurs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981450"}
{"pmid": "20981451", "title": "Effects of reduced saliva production on swallowing in patients with Sjogren's syndrome.", "content": "Effects of reduced saliva production on swallowing in patients with Sjogren's syndrome. This study aimed to further characterize the nature of swallowing dysfunction in patients with Sjogren's syndrome (SS). Subjects filled out a perception of swallow function form. Measures of stimulated salivary flow rate were also taken, and videofluoroscopic evaluation of swallowing was completed. The amount of saliva produced by patients with SS was significantly less than that produced by normal age-matched controls, and these patients perceived their swallowing to be impaired. Few statistically significant differences were found between the SS group and normal age-matched controls on temporal measures of swallowing, and 96% of swallows in the SS group were judged to be functional. There was no correlation between perception of swallowing and amount of saliva produced. No strong correlations were found between temporal measures of swallowing and salivary flow rate. Results indicated that patients with SS tend to perceive their swallowing to be worse than physiologic swallowing measures indicate. The decreased saliva production in these patients does not appear to be the cause of their perceived swallowing difficulty but may affect their sensory judgment of swallow function. Future studies will focus on how quality of saliva affects swallowing in these patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981451"}
{"pmid": "20981452", "title": "Hypochloremic metabolic alkalosis and failure to thrive: answer.", "content": "Hypochloremic metabolic alkalosis and failure to thrive: answer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981452"}
{"pmid": "20981453", "title": "Hypochloremic metabolic alkalosis and failure to thrive: question.", "content": "Hypochloremic metabolic alkalosis and failure to thrive: question.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981453"}
{"pmid": "20981454", "title": "Overexpression of SlGMEs leads to ascorbate accumulation with enhanced oxidative stress, cold, and salt tolerance in tomato.", "content": "Overexpression of SlGMEs leads to ascorbate accumulation with enhanced oxidative stress, cold, and salt tolerance in tomato. GDP-Mannose 3',5'-epimerase (GME; EC 5.1.3.18) catalyses the conversion of GDP-D-mannose to GDP-L-galactose, an important step in the ascorbic acid (AsA) biosynthesis pathway in higher plants. In this study, two members of the GME gene family were isolated from tomato (Solanum lycopersicum). Both SlGME genes encode 376 amino acids and share a 92% similarity with each other. Semi-quantitative RT-PCR indicated that SlGME1 was constantly expressed in various tissues, whereas SlGME2 was differentially expressed in different tissues. Transient expression of fused SlGME1-GFP (green fluorescent protein) and SlGME2-GFP in onion cells revealed the cytoplasmic localisation of the two proteins. Transgenic plants over-expressing SlGME1 and SlGME2 exhibited a significant increase in total ascorbic acid in leaves and red fruits compared with wild-type plants. They also showed enhanced stress tolerance based on less chlorophyll content loss and membrane-lipid peroxidation under methyl viologen (paraquat) stress, higher survival rate under cold stress, and significantly higher seed germination rate, fresh weight, and root length under salt stress. The present study demonstrates that the overexpression of two members of the GME gene family resulted in increased ascorbate accumulation in tomato and improved tolerance to abiotic stresses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981454"}
{"pmid": "20981455", "title": "Contrast sensitivity in a harbor seal (Phoca vitulina).", "content": "Contrast sensitivity in a harbor seal (Phoca vitulina). In this study, the contrast sensitivity function (CSF) of one harbor seal was determined behaviorally in a go-/no-go-experiment at an ambient light of 0.9 lx in air. Contrast sensitivity was assessed as the reciprocal value of the threshold contrast for spatial frequencies varying between 0.03 and 1.5 cycles/deg, which were displayed with contrast ranging from 0.02 to 1 on a TFT monitor with a mean luminance of 3.8 cd/m². The CSF of the harbor seal shows the general characteristics described for other species with a peak at an intermediate frequency, a low frequency roll-off and a high frequency cut-off towards the harbor seal's resolution limit determined in a previous study. The position of the CSF's peak lies at approximately 0.5 cycles/deg and adopts an absolute height of 40. These results compare well with the cat's CSF assessed at a comparable adaptation light which might reflect similarities in lifestyle and optics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981455"}
{"pmid": "20981456", "title": "Spinal anesthesia in a child with Brachmann-de Lange (Cornelia de Lange) syndrome.", "content": "Spinal anesthesia in a child with Brachmann-de Lange (Cornelia de Lange) syndrome. Providing anesthesia to patients with Brachmann-de Lange syndrome (BdLS) may be challenging, mainly because of intubation difficulty, gastroesophageal reflux disease, and aspiration complications. The use of spinal anesthesia (SA) in this population has not been reported. We report the uneventful administration of awake SA to a 7-month-old girl with BdLS who was scheduled for rectal biopsy. The current literature is reviewed to discuss the indications for SA in those patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981456"}
{"pmid": "20981457", "title": "Assessment of insulin sensitivity (S I) and glucose effectiveness (S G) from a standardized hyperglucidic breakfast test in type 2 diabetics exhibiting various levels of insulin resistance.", "content": "Assessment of insulin sensitivity (S I) and glucose effectiveness (S G) from a standardized hyperglucidic breakfast test in type 2 diabetics exhibiting various levels of insulin resistance. We investigated the measurement of insulin sensitivity (S I) with a standardized hyperglucidic breakfast (SHB) compared to minimal model analysis of an intravenous glucose tolerance test (S I-IVGTT) in 17 patients clinically referred as type 2 diabetics, not yet treated by insulin, and representing a wide range of body mass index and S I. To classify the patients, ten meal-tolerance test-based calculations of S I (MTT-S I) were compared to S I-IVGTT, and their reference values and distribution were measured on a separate sample of 200 control SHBs and 209 control IVGTTs. Eight MTT-SI indices exhibit significant correlations with S I-IVGTT: Mari's OGIS index, BIGTT-SI|0-30-120, BIGTT-SI|0-60-120, 1/G b I m, Caumo's oral minimal model (OMM), Sluiter's index \"A\" = 10(4)/(I p·G p), Matsuda's composite index given by the formula ISIcomp = 10(4)/(I b G b I m G m)(0.5), S I = 1/I b G b I m G m with r (2) ranging between 0,53 and 0,28. S I-IVGTT and S I-MTT exhibited in the lower range a very different (non-normal) pattern of distribution and thus the cutoff value for defining insulin resistance varied among indices. With such cutoffs, S I-MTT < 6.3 min(-1)/(μU/ml) 10(-4) with Caumo's OMM was the best predictor of insulin resistance defined as S I-IVGTT < 2 min(-1)/(μU/ml) 10(-4). Other indices, including OGIS and BIGTT, resulted in more misclassifications of patients. HOMA-IR and QUICKI were poor predictors. The formula [Formula: see text] satisfactorily predicts IVGTT-derived glucose effectiveness in type 2 diabetics. Thus, SHB appears suitable for the measurement of S I and S G in type 2 diabetics, and the OMM seems to provide the most accurate SHB-derived index in this population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981457"}
{"pmid": "20981459", "title": "Glycation research in amino acids: a place to call home.", "content": "Glycation research in amino acids: a place to call home. This is an introduction to a collection of review articles by leading investigators in the field of protein glycation research, see following articles in this issue. With this we launch a section of this journal now established for presentation of research results, reviews and commentaries on protein glycation and related topics. Glycation is the spontaneous, non-enzymatic reaction of protein with saccharides and saccharide derivatives. Although studied in the modern scientific era for over 100 years, its importance in the biology, medicine, food and nutrition, pharmacology and toxicology, and technological processing remains intriguingly undisclosed. In this section of amino acids, research on glycation is a qualifier for publication. Glycation research now has a place to call home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981459"}
{"pmid": "20981458", "title": "Synergic effect of α-tocopherol and naringenin in transglutaminase-induced differentiation of human prostate cancer cells.", "content": "Synergic effect of α-tocopherol and naringenin in transglutaminase-induced differentiation of human prostate cancer cells. Prostate cancer is the second most common cancer in men worldwide. Its prevention and treatment remain a challenge to clinicians. Thus, there is an urgent need to discover novel, less toxic, and more effective therapies for patients. Many vitamins and related chemicals, including vitamin E, (tocopherols) have shown their anti-cancer activities as anti-oxidants, activators of transcription factors or factors influencing epigenetic events. Although laboratory tests including the use of animal models showed that this vitamin may have anticancer properties, whether it can effectively prevent the development and/or progression of prostate cancer in humans remains to be intensively studied. This review provides up-to-date information regarding the recent outcomes of laboratory, epidemiology and/or clinical trials on the effects of tocopherols on prostate cancer development, along with our last observations on a combined treatment of a prostate cancer cell line (PC-3) with two natural antineoplastic compounds, naringenin (NG) and α-tocopherol (α-TOC). We report the synergic effect of α-TOC and NG in transglutaminase-induced differentiation of human PC-3 prostate cancer cells. While our results are based on one histological class of tumor, the most significant implication of this observation is that establishes a new way in the screening for detecting new differentiative antineoplastic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981458"}
{"pmid": "20981460", "title": "Theoretical study of hydrogen bond interactions of fluvastatin with ι-carrageenan and λ-carrageenan.", "content": "Theoretical study of hydrogen bond interactions of fluvastatin with ι-carrageenan and λ-carrageenan. The binding of the reductase inhibitor drug fluvastatin, hydroxy-3-methylglutaryl coenzyme A, with the hydrophilic ι- or λ-carrageenan polymers, serving as potential controllers of the drug's release rate, have been studied at the density functional level of theory with the B3LYP exchange correlation functional. Three low energy conformers of fluvastatin have been calculated. The vibrational spectroscopic properties calculated for the most stable conformer were in satisfactory agreement with the experimental data. A series of hydrogen bonded complexes of the most stable conformer of fluvastatin anion with low molecular weight models of the polymers have been fully optimized. In almost all, intermolecular H-bonds are formed between the sulfate groups of ι- or λ-carrageenan and fluvastatin's hydroxyls, resulting in a red shift of the fluvastatin's O - H stretching vibrations. Cooperative intramolecular H-bonds within fluvastatin or ι-, λ-carrageenan are also present. The BSSE and ZPE corrected interaction energies were estimated in the range 281-318 kJ mol⁻¹ for ι-carrageenan - fluvastatin and 145-200 kJ mol⁻¹ for λ-carrageenan - fluvastatin complexes. The electron density (ρ (bcp)) and Laplacian (∇²ρ (bcp)) properties at critical points of the intermolecular hydrogen bonds, estimated by AIM (atoms in molecules) calculations, have a low and positive character (∇²ρ(bcp) > 0), consistent with the electrostatic character of the hydrogen bonds. The structural and energetic data observed, as well as the extent of the red shift of the fluvastatin's O - H stretching vibrations upon complex formation and the properties of electron density show a stronger binding of fluvastatin to ι- than to λ-carrageenan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981460"}
{"pmid": "20981462", "title": "Development of a simulation system in mandibular orthognathic surgery based on integrated three-dimensional data.", "content": "Development of a simulation system in mandibular orthognathic surgery based on integrated three-dimensional data. Surgical simulation should reflect the 3D movement of dentition and the resultant movement of the osteotomized segments, which can influence surgical outcome. The present study was aimed at developing a new simulation system that enables virtual osteotomy of a given surgical situation and evaluation of the bony interference between the osteotomized segments of the mandible. The data of 3D computer tomography (CT) for maxillomandibular dental casts were integrated into the standard coordinates of a 3D cephalogram. To evaluate the accuracy of the system, measurement errors of the 3D CT virtual model from a dry skull were compared with the computer simulation system and a contact-type 3D digitizer. To examine the clinical accessibility, 15 mandibular prognathism patients with mild to severe asymmetry were evaluated with the simulation program. The average error of measurement in all directions was 1.31 mm. It was possible to simulate various osteotomy procedures by conversion of the 3D coordinates of the dental cast and CT data into the standard coordinate system of a 3D cephalogram. Using this simulation system, it was possible to prevent condylar torque or segment malpositioning by removing the bony interference visualized by a 3D virtual model. A new system, which enables the precise visualization of osteotomized segments and calculation of bony interference, was proposed in the present study. This new system provides an acceptable precision of treatment planning of orthognathic surgery, especially for facial asymmetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981462"}
{"pmid": "20981461", "title": "Diffuse swelling of the buccal mucosa and palate as first and only manifestation of an extranodal non-Hodgkin 'double-hit' lymphoma: report of a case.", "content": "Diffuse swelling of the buccal mucosa and palate as first and only manifestation of an extranodal non-Hodgkin 'double-hit' lymphoma: report of a case. Most of the lymphomas arising in the oral cavity are of B-cell origin. Among these, diffuse large B-cell lymphomas are the most common. Diffuse large B-cell lymphomas may exhibit more than one chromosomal rearrangement and are then referred to as 'double-hit' or 'triple-hit' lymphomas. We present a case of an intraoral 'double-hit' lymphoma in a 76-year-old male who had been referred by an oral surgeon in private practice. Intraoral examination exhibited a firm, exophytic lesion in the region of the right hard palate and buccal mucosa with extension to the soft palate. Radiographic examination exhibited a massive thickening of the right sinus membrane, and arrosion of the lateral and basal cortical sinus walls in the right maxilla. After diagnosis of the lesion, the patient was treated with six cycles of chemotherapy. Lymphomas arising within the oral cavity account for less than 5% of all oral malignancies and typically affect the palatine tonsils and the palate. 'Double-hit' lymphomas are associated with older age, usually present with an advanced stage of disease, and show an aggressive clinical behaviour. They normally have a poor prognosis, even when treated with intensive chemotherapy regimens. Nevertheless, in the case presented, the patient was free of symptoms 1 year after initial diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981461"}
{"pmid": "20981463", "title": "Feasibility of diagnosing influenza within 24 hours of symptom onset in children 1-3 years of age.", "content": "Feasibility of diagnosing influenza within 24 hours of symptom onset in children 1-3 years of age. Diagnosing influenza at an early stage of illness is important for the initiation of effective antiviral treatment. However, especially in young children, influenza often commences with an abrupt onset of fever, with full-blown respiratory symptoms developing only later. We determined the feasibility of diagnosing influenza in young children already during the first signs of the illness. During confirmed influenza activity, we obtained nasal swabs from children aged 1-3 years who presented as outpatients within 24 hours of the onset of fever (≥38.0°C). The specimens were tested for influenza viruses with viral culture, antigen detection, PCR, and a rapid point-of-care test (Actim Influenza A&B, Medix Biochemica, Finland). In addition, follow-up specimens were obtained from a proportion of children 3-7 days later. Influenza virus was detected already within 24 hours of symptom onset in 56 of 61 (92%; 95% CI 82-97%) children in whom influenza was eventually confirmed in the laboratory. A total of 158 rapid tests performed within 24 hours of symptom onset yielded a sensitivity of 90% (95% CI 74-98%) for influenza A viruses but only 25% (95% CI 3-61%) for influenza B viruses (P < 0.001), resulting in an overall sensitivity of 77% (95% CI 61-89%) and specificity of 99% (95% CI 95-100%) for all influenza viruses. In most young children, influenza can already be accurately diagnosed within 24 hours of symptom onset. The rapid point-of-care test used was sensitive and specific for diagnosing influenza A, but its sensitivity for influenza B was limited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981463"}
{"pmid": "20981464", "title": "Identification of clinically relevant viridans group streptococci by phenotypic and genotypic analysis.", "content": "Identification of clinically relevant viridans group streptococci by phenotypic and genotypic analysis. Two phenotypic and three molecular methods were assessed for their ability to identify viridans group streptococci (VGS) to the species level. A panel of 23 clinical isolates, comprising strains isolated from infective endocarditis, blood cultures, pleural and peritoneal fluid, and 19 type/reference strains were analyzed. Identification was performed using two conventional phenotypic methods: API® rapid ID 32 Strep and the VITEK® 2 system, and genotypic analysis of the nucleotide sequence of the housekeeping gene sodA, restriction patterns generated by restriction fragment length polymorphism (RFLP) of the 16S rRNA gene and multilocus sequence analysis (MLSA) of seven housekeeping genes. The API® rapid ID 32 Strep accurately speciated 79% of the strains assessed, while the VITEK® 2 generated a successful identification for 55%, presenting limitations particularly with regard to species belonging to the mitis group. RFLP of the 16S rRNA gene correctly speciated 24% of the strains, having failed to allocate a species for 36% of the isolates examined. In contrast, sequence analysis of the sodA gene provided a correct identification for 95% of the strains assessed, while identification using the MLSA technique was unsuccessful due to practical limitations. The results generated herein indicate that no single methodology can be used to provide an accurate identification to the species level of all VGS, although nucleotide sequence analysis of the sodA gene proved to be useful in providing reliable speciation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981464"}
{"pmid": "20981465", "title": "Six-month follow-up multicenter prospective study of 368 patients, phototypes III to V, on epilation efficacy using an 810-nm diode laser at low fluence.", "content": "Six-month follow-up multicenter prospective study of 368 patients, phototypes III to V, on epilation efficacy using an 810-nm diode laser at low fluence. Laser hair removal is currently a popular cosmetic procedure. Traditional high-fluence laser treatment for hair elimination is associated with discomfort and adverse events and it is restricted to low phototype skins. A multicenter study of hair epilation with low fluences and high repetition pulse rate using an 810-nm diode laser was carried out on 368 patients (phototypes III to V) to test its efficacy in a 6-month follow-up after five treatments on the face and various body areas. Objective and subjective assessment as well as histologies show a high index of patient satisfaction due to high efficacy of hair elimination, also proved histologically by the damage observed at hair structure level. Results obtained a high degree of patient satisfaction and a low index of adverse events. Laser epilation was well accepted regarding discomfort and was also complication-free for dark and tanned skins. Treatment is easy to conduct and requires adapting the movement of the hand-piece to a constant speed in order to achieve high-energy deposit on tissue avoiding risks of burning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981465"}
{"pmid": "20981466", "title": "Achilles paratendonitis as the initial manifestation of rheumatoid arthritis.", "content": "Achilles paratendonitis as the initial manifestation of rheumatoid arthritis. We report a case of rheumatoid arthritis in which the earliest symptom was bilateral paratendonitis of the Achilles tendons, followed by paratendonitis of a finger extensor. A series of musculoskeletal ultrasonograms revealed a progression from paratendonitis of the extensor tendon to erosive synovitis of the adjacent metacarpophalangeal joint. High-resolution ultrasonography combined with power Doppler imaging seems to be a useful and convenient tool both for diagnosing paratendonitis early and for closely monitoring the progressing inflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981466"}
{"pmid": "20981467", "title": "Dicoogle - an open source peer-to-peer PACS.", "content": "Dicoogle - an open source peer-to-peer PACS. Picture Archiving and Communication Systems (PACS) have been widely deployed in healthcare institutions, and they now constitute a normal commodity for practitioners. However, its installation, maintenance, and utilization are still a burden due to their heavy structures, typically supported by centralized computational solutions. In this paper, we present Dicoogle, a PACS archive supported by a document-based indexing system and by peer-to-peer (P2P) protocols. Replacing the traditional database storage (RDBMS) by a documental organization permits gathering and indexing data from file-based repositories, which allows searching the archive through free text queries. As a direct result of this strategy, more information can be extracted from medical imaging repositories, which clearly increases flexibility when compared with current query and retrieval DICOM services. The inclusion of P2P features allows PACS internetworking without the need for a central management framework. Moreover, Dicoogle is easy to install, manage, and use, and it maintains full interoperability with standard DICOM services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981467"}
{"pmid": "20981469", "title": "How much money can be saved by applying intravenous antibiotics once instead of several times a day?", "content": "How much money can be saved by applying intravenous antibiotics once instead of several times a day? The preparation, administration and monitoring of intravenous (IV) applications are time consuming and require human resources. We estimated the potential time and cost savings by replacing antibiotics given 3-4 times daily with antibiotics with similar spectrum and efficacy given once daily. The savings of indirect costs were estimated based on the antibiotic consumption data of a two-year period (i.e. 2007 and 2008), a nurse's mean workload per application and the average nurse's salary in Switzerland. The consumption of IV antibiotics in 2007 and 2008 at the University Hospital of Basel was 29.0 and 32.2 defined daily doses (DDD) per 100 patient days, respectively. Nurses spent an estimated 13,786 h on the application of the estimated 82,715 does of IV antibiotics. A total of 56,404 applications or nursing staff time costs of 338,436 Swiss Francs (CHF; 236,669 <euro>), equal to 16% of the overall costs spent on purchasing antibiotics in the year 2008, may have been saved by switching multiple-dose antibiotics to a hypothetical once-daily antibiotic. Including disposable materials, 21% or 456,884 CHF (319,499 <euro>) could be saved annually (purchase costs not taken into account). We found a potential cost saving of 21% of the purchase costs in a 750-bed institution. Hence, indirect costs should be included in the calculation of the total cost for the application of broad-spectrum IV antibiotics. Switching from a 3-4 times daily application to a once-daily antibiotic should be considered if a once-daily antibiotic is deemed equally effective and has a similar spectrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981469"}
{"pmid": "20981471", "title": "Hydroxamate siderophores of the ectomycorrhizal fungi Suillus granulatus and S. luteus.", "content": "Hydroxamate siderophores of the ectomycorrhizal fungi Suillus granulatus and S. luteus. Despite indications that S. granulatus and S. luteus release iron-chelating compounds, the exact spectrum of ferric hydroxamates synthesized by these two Suillus species remained unclear. Hence the aim of this study was to identify all of the main siderophores produced by these two ectomycorrhizal fungal species under pure culture conditions. By means of HPLC and LC-MS analyses we show that S. granulatus releases cyclic and linear fusigen, ferrichrome, coprogen and triacetylfusarinine C into the nutrient medium, while S. luteus culture filtrates contain cyclic and linear fusigen, ferricrocin and coprogen. All of the different siderophores were identified on basis of reference compounds and their specific MS spectra which were recorded on a high resolution MS in positive electrospray ionisation mode. Initial HPLC separations were performed on a C-18 stationary phase, using an acidic eluent (0.1% formic acid in water and acetonitrile) in gradient mode. The potential of these two ectomycorrhizal fungal species to produce siderophores representing three different groups of hydroxamates is discussed in relation to its ecological significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981471"}
{"pmid": "20981474", "title": "A dynamic mechanical thermal analysis study of the viscoelastic properties and glass transition temperature behaviour of bioresorbable polymer matrix nanocomposites.", "content": "A dynamic mechanical thermal analysis study of the viscoelastic properties and glass transition temperature behaviour of bioresorbable polymer matrix nanocomposites. The application of bioresorbable polymer nanocomposites in orthopaedics offer the potential to address several of the limitations associated with the use of metallic implants. Their enhanced biological performance has been demonstrated recently, but until now relatively little work has been reported on their mechanical properties. To this end, the viscoelastic properties and T(g) of bioresorbable polylactide-co-glycolide/α-tricalcium phosphate nanocomposites were investigated by dynamic mechanical thermal analysis. At room temperature of approximately 20°C, the storage moduli of the nanocomposites were generally higher than the storage modulus of the unfilled polymer due to the stiffening effect of the nano-particles. However at physiological temperature of approximately 37°C, the storage moduli of the nanocomposites decreased from 6.2 to 15.4% v/v nano-particle loadings. Similarly the T(g) of the nanocomposites also decreased from 6.2 to 15.4% v/v nano-particle loadings. These effects were thought to be due to weak interfacial bonding between the nano-particles and polymer matrix. The storage moduli at 37°C and T(g) increased from the minimum value when the particle loading was raised to 25.7 and 34.2% v/v loadings. SEM and particle size distribution histograms showed that at these loadings, there was a broad particle size distribution consisting of nano-particles and micro-particles and that some particle agglomeration was present. The consequent reduction in the interfacial area and the number of weak interfaces presumably accounts for the rise in the storage modulus at 37°C and the T(g).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981474"}
{"pmid": "20981468", "title": "Pitfalls of \"hyper\"-IgM syndrome: a new CD40 ligand mutation in the presence of low IgM levels. A case report and a critical review of the literature.", "content": "Pitfalls of \"hyper\"-IgM syndrome: a new CD40 ligand mutation in the presence of low IgM levels. A case report and a critical review of the literature. Here, we report on a male infant with low serum IgG, IgA and IgM levels who suffered from Pneumocystis jirovecii and cytomegalovirus (CMV) pneumonia. The patient was tested to be HIV-negative. Absolute and relative numbers of lymphocyte subsets were normal, excluding the diagnosis of an X-linked agammaglobulinaemia (Bruton's disease). Despite the decreased serum IgM level, an X-linked hyper-IgM syndrome (X-HIGM) was considered. X-HIGM is a rare immunodeficiency usually characterised by recurrent severe opportunistic infections, low serum IgG and IgA, but normal or increased serum IgM. The syndrome is caused by mutations of the CD40 ligand (CD40L) gene. In our patient, CD40L mutation analysis proved a novel mutation at codon 257 associated with non-detectable expression of CD40L on the surface of activated T cells. A literature search revealed that approximately 6.4% of X-HIGM patients had been found to have low serum IgM levels. Our statistical analysis of the IgM levels as reported by different studies arouses suspicion that many patients with low IgM levels may not have undergone diagnostic procedures for X-HIGM. In summary, in this report and critical review of the literature, we described a new mutation of CD40L and highlighted the pitfalls of the diagnosis of X-HIGM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981468"}
{"pmid": "20981473", "title": "Evaluating cell proliferation based on internal pore size and 3D scaffold architecture fabricated using solid freeform fabrication technology.", "content": "Evaluating cell proliferation based on internal pore size and 3D scaffold architecture fabricated using solid freeform fabrication technology. The scaffold, as a medical component to regenerate tissues or organs in humans, plays an important role in tissue engineering. Recently, solid freeform fabrication (SFF) technology using computer-assisted methods was applied to address the problems of conventional fabrication methods in which the internal/outer architectures cannot be controlled. In this report, we propose suitable scaffolds for bone tissue regeneration considering the internal pore size and scaffold architecture. Poly(propylene fumarate) was used as the biodegradable photopolymer, and scaffolds were fabricated using microstereolithography (MSTL). We observed the relationship between the internal pores and architecture, and the proliferation of pre-osteoblast cells. To demonstrate the superiority of MSTL, we fabricated conventional and SFF scaffolds, and measured the cell proliferation rates for each. The results showed that cell proliferation on the MSTL scaffold was clearly superior and indicated that MSTL would be a good replacement for current conventional methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981473"}
{"pmid": "20981476", "title": "Endoglin suppresses human prostate cancer metastasis.", "content": "Endoglin suppresses human prostate cancer metastasis. Endoglin is a transmembrane receptor that suppresses human prostate cancer (PCa) cell invasion. Small molecule therapeutics now being tested in humans can activate endoglin signaling. It is not known whether endoglin can regulate metastatic behavior, PCa tumor growth, nor what signaling pathways are linked to these processes. This study sought to investigate the effect of endoglin on these parameters. We used a murine orthotopic model of human PCa metastasis, designed by us to measure effects at early steps in the metastatic cascade, and implanted PCa cells stably engineered to express differing levels of endoglin. We now extend this model to measure cancer cells circulating in the blood. Progressive endoglin loss led to progressive increases in the number of circulating PCa cells as well as to the formation of soft tissue metastases. Endoglin was known to suppress invasion by activating the Smad1 transcription factor. We now show that it selectively activates specific Smad1-responsive genes, including JUNB, STAT1, and SOX4. Increased tumor growth and increased Ki67 expression in tissue was seen only with complete endoglin loss. By showing that endoglin increased TGFβ-mediated suppression of cell growth in vitro and TGFβ-mediated signaling in tumor tissue, loss of this growth-suppressive pathway appears to be implicated at least in part for the increased size of endoglin-deficient tumors. Endoglin is shown for the first time to suppress cell movement out of primary tumor as well as the formation of distant metastasis. It is also shown to co-regulate tumor growth and metastatic behavior in human PCa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981476"}
{"pmid": "20981475", "title": "Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cells.", "content": "Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cells. Several data of the past years clearly indicated that the fusion of tumor cells and tumor cells or tumor cells and normal cells can give rise to hybrids cells exhibited novel properties such as an increased malignancy, drug resistance, or resistance to apoptosis. In the present study we characterized hybrid cells derived from spontaneous fusion events between the breast epithelial cell line M13SV1-EGFP-Neo and two breast cancer cell lines: HS578T-Hyg and MDA-MB-435-Hyg. Short-tandem-repeat analysis revealed an overlap of parental alleles in all hybrid cells indicating that hybrid cells originated from real cell fusion events. RealTime-PCR-array gene expression data provided evidence that each hybrid cell clone exhibited a unique gene expression pattern, resulting in a specific resistance of hybrid clones towards chemotherapeutic drugs, such as doxorubicin and paclitaxel, as well as a specific migratory behavior of hybrid clones towards EGF. For instance, M13MDA435-4 hybrids showed a marked resistance towards etoposide, doxorubicin and paclitaxel, whereas hybrid clones M13MDA-435-1 and -2 were only resistant towards etoposide. Likewise, all investigated M13MDA435 hybrids responded to EGF with an increased migratory activity, whereas the migration of parental MDA-MB-435-Hyg cells was blocked by EGF, suggesting that M13MDA435 hybrids may have acquired a new motility pathway. Similar findings have been obtained for M13HS hybrids. We conclude from our data that they further support the hypothesis that cell fusion could give rise to drug resistant and migratory active tumor (hybrid) cells in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981475"}
{"pmid": "20981472", "title": "Chronic beryllium disease: an updated model interaction between innate and acquired immunity.", "content": "Chronic beryllium disease: an updated model interaction between innate and acquired immunity. During the last decade, there have been concerted efforts to reduce beryllium (Be) exposure in the workplace and thereby reduce potential cases of this occupational lung disorder. Despite these efforts, it is estimated that there are at least one million Be-exposed individuals in the U.S. who are potentially at risk for developing chronic beryllium disease (CBD). Previously, we reviewed the current CBD literature and proposed that CBD represents a model interaction between innate and acquired immunity (Sawyer et al., Int Immunopharmacol 2:249-261, 2002). We closed this review with a section on \"future directions\" that identified key gaps in our understanding of the pathogenesis of CBD. In the intervening period, progress has been made to fill in some of these gaps, and the current review will provide an update on that progress. Based on recent findings, we provide a new hypothesis to explain how Be drives sustained chronic inflammation and granuloma formation in CBD leading to progressive compromised lung function in CBD patients. This paradigm has direct implications for our understanding of the development of an immune response to Be, but is also likely applicable to other immune-mediated lung diseases of known and unknown etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981472"}
{"pmid": "20981470", "title": "Vesicular distribution of Secretory Pathway Ca²+-ATPase isoform 1 and a role in manganese detoxification in liver-derived polarized cells.", "content": "Vesicular distribution of Secretory Pathway Ca²+-ATPase isoform 1 and a role in manganese detoxification in liver-derived polarized cells. Manganese is a trace element that is an essential co-factor in many enzymes critical to diverse biological pathways. However, excess Mn(2+) leads to neurotoxicity, with psychiatric and motor dysfunction resembling parkinsonism. The liver is the main organ for Mn(2+) detoxification by excretion into bile. Although many pathways of cellular Mn(2+) uptake have been established, efflux mechanisms remain essentially undefined. In this study, we evaluated a potential role in Mn(2+) detoxification by the Secretory Pathway Ca(2+), Mn(2+)-ATPase in rat liver and a liver-derived cell model WIF-B that polarizes to distinct bile canalicular and sinusoidal domains in culture. Of two known isoforms, only secretory pathway Ca(2+)-ATPase isoform 1 (SPCA1) was expressed in liver and WIF-B cells. As previously observed in non-polarized cells, SPCA1 showed overlapping distribution with TGN38, consistent with Golgi/TGN localization. However, a prominent novel localization of SPCA1 to an endosomal population close to, but not on the basolateral membrane was also observed. This was confirmed by fractionation of rat liver homogenates which revealed dual distribution of SPCA1 to the Golgi/TGN and a fraction that included the early endosomal marker, EEA1. We suggest that this novel pool of endosomes may serve to sequester Mn(2+) as it enters from the sinusoidal/basolateral domains. Isoform-specific partial knockdown of SPCA1 delayed cell growth and formation of canalicular domain by about 30% and diminished viability upon exposure to Mn(2+). Conversely, overexpression of SPCA1 in HEK 293T cells conferred tolerance to Mn(2+) toxicity. Taken together, our findings suggest a role for SPCA1 in Mn(2+) detoxification in liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981470"}
{"pmid": "20981478", "title": "Human B cell development and antibody production in humanized NOD/SCID/IL-2Rγ(null) (NSG) mice conditioned by busulfan.", "content": "Human B cell development and antibody production in humanized NOD/SCID/IL-2Rγ(null) (NSG) mice conditioned by busulfan. Busulfan treatment as a chemotherapeutic agent has been considered an alternative approach in xenograft model because it offers a simple, convenient, effective, and less toxic conditioning regimen. To investigate busulfan effects on the reconstitution of human immune cells and the generation of immune response to foreign antigens, we generated humanized NOD/SCID/IL-2Rγ(null) (NSG) mice conditioned either busulfan or total body irradiation (TBI) with hCD34(+) CB cells. Busulfan resulted in a high survival rate and effective reconstitution of human immune cells including B, T, macrophage, and dendritic cells in humanized NSG mice, compared to that of TBI. Moreover, the humanized NSG mice conditioned busulfan showed effective B cell development and thereby the high production of human antibody against immunized antigen. Humanized mice conditioned by busulfan provide a powerful and versatile tool for studying the entire process of human B-lymphocyte development and for producing specific human antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981478"}
{"pmid": "20981477", "title": "Binding of the general odorant binding protein of Bombyx mori BmorGOBP2 to the moth sex pheromone components.", "content": "Binding of the general odorant binding protein of Bombyx mori BmorGOBP2 to the moth sex pheromone components. Insects use olfactory cues to locate hosts and mates. Pheromones and other semiochemicals are transported in the insect antenna by odorant-binding proteins (OBPs), which ferry the signals across the sensillum lymph to the olfactory receptors (ORs). In the silkworm, Bombyx mori (L.), two OBP subfamilies, the pheromone-binding proteins (PBPs) and the general odorant-binding proteins (GOBPs), are thought to be involved in both sensing and transporting the sex pheromone, bombykol [(10E,12Z)-hexadecadien-1-ol], and host volatiles, respectively. Quantitative examination of transcript levels showed that BmorPBP1 and BmorGOBP2 are expressed specifically at very high levels in the antennae, consistent with their involvement in olfaction. A partitioning binding assay, along with other established assays, showed that both BmorPBP1 and BmorGOBP2 bind to the main sex pheromone component, bombykol. BmorPBP1 also binds equally well to the other major pheromone component, bombykal [(10E,12Z)-hexadecadienal], whereas BmorGOBP2 discriminates between the two ligands. The pheromone analogs (10E,12Z)-hexadecadienyl acetate and (10E,12Z)-octadecadien-1-ol bind to both OBPs more strongly than does bombykol, suggesting that they could act as potential blockers of the response to sex pheromone by the male. These results are supported by further comparative studies of molecular docking, crystallographic structures, and EAG recording as a measure of biological response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981477"}
{"pmid": "20981479", "title": "Combined impact of sexual risk behaviors for HIV seroconversion among women in Durban, South Africa: implications for prevention policy and planning.", "content": "Combined impact of sexual risk behaviors for HIV seroconversion among women in Durban, South Africa: implications for prevention policy and planning. The objective of this study was to estimate the joint impact of demographic and sexual risk behaviors on HIV acquisition. A total of 2,523 HIV seronegative women were recruited through three community based studies in Durban, South Africa. Point and interval estimates of partial population attributable risk (PAR) were used to quantify the proportion of HIV seroconversions which can be prevented if a combination of risk factors is eliminated from a target population. More than 80% of the observed HIV acquisitions were attributed to five risk factors: lack of cohabitation, frequency of sex, sexually transmitted infections (STIs), incidence of pregnancy and not being employed/no income. Structural factors such as minimizing migratory patterns by ensuring cohabitation of partners, access to treatment of STIs, income generation and safe sex negotiation skills are likely to play an important role in future prevention strategies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981479"}
{"pmid": "20981481", "title": "Soft drinks, sweetened beverages and risk of pancreatic cancer.", "content": "Soft drinks, sweetened beverages and risk of pancreatic cancer. Soft drinks usually contain sugar and caffeine that might influence pancreatic carcinogenesis. We considered the association between carbonated drink consumption and pancreatic cancer risk in an Italian case-control study conducted in 1991-2008 on 326 pancreatic cancer cases and 652 matched controls. We also combined the results from all the studies on soft drinks or sweetened beverages and pancreatic cancer published before June 2010, using a meta-analytic approach. In the case-control study, compared with non-drinkers, the multivariate odds ratio was 1.02 (95% confidence interval, CI, 0.72-1.44) for carbonated drink consumers and 0.89 (95% CI 0.53-1.50) for regular consumers (at least one drink/day). Besides our study, from the literature search, we identified 4 other case-control (1,919 cases) and 6 cohort studies (2,367 cases). The pooled relative risks (RR) for soft drink consumers vs. non-consumers were 0.97 (95% CI 0.81-1.16) for case-control, 1.05 (95% CI 0.94-1.17) for cohort, and 1.02 (95% CI 0.93-1.12) for all studies. The pooled RRs for heavy drinkers were 1.08 (95% CI 0.73-1.60) for case-control, 1.21 (95% CI 0.90-1.63) for cohort, and 1.16 (95% CI 0.93-1.45) for all studies. In conclusion, soft drink consumption is not materially related to pancreatic cancer risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981481"}
{"pmid": "20981482", "title": "Increased risk of adenomas in individuals with a family history of colorectal cancer: results of a meta-analysis.", "content": "Increased risk of adenomas in individuals with a family history of colorectal cancer: results of a meta-analysis. It is unclear to what extent the increased risk of colorectal cancer in individuals with a family history of colorectal cancer and no known genetic disorders is associated with a higher adenoma prevalence. Our aim is to estimate the relative difference in adenoma prevalence and its age-pattern in individuals with a family history of colorectal cancer compared to those without. We performed a literature search to identify colonoscopy studies reporting the adenoma prevalence by age. Using multilevel logistic regression, we examined how the adenoma prevalence by age differed between individuals with and without a family history of colorectal cancer. We excluded members of families with a known genetic disorder. Thirteen colonoscopy studies were identified. The adenoma prevalence was significantly higher in individuals with a family history than in those without (OR 1.7, 95% CI 1.4-3.5). The adenoma prevalence increased with age (OR per year of age 1.06, 95% CI 1.05-1.07). The age trend did not differ significantly between the two groups. Individuals with a family history of colorectal cancer have a considerably higher prevalence of adenomas compared to individuals without a family history. This is consistent with their increased risk of colorectal cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981482"}
{"pmid": "20981480", "title": "Discussion of sexual risk behavior in HIV care is infrequent and appears ineffectual: a mixed methods study.", "content": "Discussion of sexual risk behavior in HIV care is infrequent and appears ineffectual: a mixed methods study. Consensus guidelines in HIV care call for clinicians to provide a brief sexual risk behavioral intervention in each visit. Studies based on participant reports find this occurs infrequently, but studies based on direct observation of clinical encounters are lacking. We conducted a mixed method study that used audio recordings of 116 routine outpatient visits by 58 different patients with HIV, in five different practice sites. Transcripts of the visits were coded and analyzed using a quantitative system. In addition, we conducted a qualitative analysis of the dialogue segments in which sexual risk behaviors arose as a topic. Discussion of sexual risk behavior occurred in 10 visits, and was generally quite brief. Two visits featured substantial counseling about sexual risk reduction; two others included substantial discussion which was not evidently directed at the patient's changing behavior. Cues suggesting a need or opportunity for such discussion that physicians did not follow up on occurred in seven additional visits. Interactions about sexual risk had less patient engagement than interactions about other health behaviors. Physicians seldom provide sexual risk reduction counseling in HIV care, even where specific indications are present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981480"}
{"pmid": "20981483", "title": "Triphenyltin induced growth inhibition and antioxidative responses in the green microalga Scenedesmus quadricauda.", "content": "Triphenyltin induced growth inhibition and antioxidative responses in the green microalga Scenedesmus quadricauda. The toxicity of organotin compounds in the environment is closely related to their uptake by microorganisms and delivery through the food chain. The population at low trophic levels like microalgae plays an important role in this aspect. In this study, the toxic effects of triphenyltin (TPT) on Scenedesmus quadricauda were assessed at the population, cellular and subcellular levels. The alga was exposed to TPT of up to 64 μg l(-1) (nearly lethal concentration), but the algal growth was inhibited significantly when TPT was elevated to 8 μg l(-1). This growth inhibition was correlated to the presence of oxidative stress as evidenced by the accumulation of malondialdehyde (MDA) and confirmed by fluorescent probing of the intracellular reactive oxygen species (ROS) levels. The imbalanced activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) may lead to an accumulation of intracellular H(2)O(2), which can initiate an oxidative damage to cell components and cause growth inhibition and finally cell death. The detachment of plasma membrane from cell wall, the structural change of chloroplasts as well as the increased number and size of starch granules together with electron-dense deposits in chloroplasts were noticed through electron microscopic examination. It was suggested that mitochondria, chloroplasts and protoplasm might be the direct targets of TPT toxicity. This study confirmed that TPT poisoning on phytoplankton can happen at very low concentrations. There existed different defense mechanisms e.g., antioxidant enzyme activation, starch accumulation and possibly metal sequestration in algal species as the means to resist TPT toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981483"}
{"pmid": "20981484", "title": "Site-activated chelators derived from anti-Parkinson drug rasagiline as a potential safer and more effective approach to the treatment of Alzheimer's disease.", "content": "Site-activated chelators derived from anti-Parkinson drug rasagiline as a potential safer and more effective approach to the treatment of Alzheimer's disease. chelators can modulate β-amyloid accumulation, protect against tau hyperphosphorylation, and block metal-related oxidative stress, and thereby hold considerable promise as effective anti-AD drugs. At present, a growing interest is focusing on increasing the efficacy and targeting of chelators through drug design. To this end, we have developed a new class of multifunctional prochelators from three FDA- approved drugs rasagiline, rivastigmine, and donepezil or tacrine. HLA20 A was designed by merging the important pharmacophores of rasagiline, rivastigmine, and donepezil into our newly developed multifunctional chelator HLA20. M30D was constructed using the key pharmacophoric moieties from rasagiline, rivastigmine, and tacrine. Experiments showed that both compounds possess potent anti-acetylcholinesterase (AChE) activity in vitro with weak inhibition of butyrylcholinesterase (BuChE), and without significant metal-binding activity. M30D was found also to be a highly potent MAO A inhibitor with moderate inhibition of MAO B in vitro. Both HLA20 and M30D can be activated by inhibition of AChE to release active chelators HLA20 and M30, respectively. HLA20 and M30 have been shown to be able to modulate amyloid precursor protein regulation and beta-amyloid reduction, suppress oxidative stress, and passivate excess metal ions (Fe, Cu, and Zn). Compared with the activated chelator HLA20 or M30, both HLA20A and M30D exhibited lower cytotoxicity in SH-SY5Y neuroblastoma cells, substantiating the prochelator strategy for minimizing toxicity associated with poor targeted chelators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981484"}
{"pmid": "20981486", "title": "The correlation of mentoring and job satisfaction: a pilot study of mental health professionals.", "content": "The correlation of mentoring and job satisfaction: a pilot study of mental health professionals. A pilot study examined the relationship between job satisfaction and perceived mentoring among 56 mental health supervisors and practitioners in a county mental health agency. Participants completed the Alleman Mentoring Activities Questionnaires and the Job Descriptive Index and Job in General Scale. Practitioners who perceived they were involved in mentoring relationships with supervisors were more satisfied with their jobs than those who perceived that they were not involved in mentoring relationships. The mentoring functions of sponsoring, assigning challenging tasks, and demonstrating trust predicted job satisfaction. Recommendations include incorporating mentoring functions in supervisory training to increase mental health professionals' job satisfaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981486"}
{"pmid": "20981487", "title": "Engaging religious experience in stroke rehabilitation.", "content": "Engaging religious experience in stroke rehabilitation. In this article, I respond to the problem of engaging with religious experience in health care environments. In particular, I illuminate the relational aspects of religious experience in the context of stroke rehabilitation by providing a commentary on data gathered from existing qualitative research and personal narratives in the acute and rehabilitation phases of stroke recovery. In so doing, I address the necessary balance of empathy and alterity in the art of resonant listening. I also provide some critical reflections on interdisciplinary approaches to engaging with religious experience with reference to a largely overlooked group of health care professionals-hospital chaplains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981487"}
{"pmid": "20981488", "title": "Apparitions and possessions as boundary objects: an exploration into some tensions between mental health care and pastoral care.", "content": "Apparitions and possessions as boundary objects: an exploration into some tensions between mental health care and pastoral care. Apparitions and possessions can be taken as genuine spiritual events or as symptoms of psychopathology. We focus upon occasions when the two seemingly conflicting \"interpretations\" co-exist in order to explore these phenomena as kinds of boundary objects-polymorphous realities stable and graspable enough, yet belonging to different worlds at once. Related diagnostic knowledge is often uncertain and always incomplete. Yet it enables authoritative and effective professional interventions. We conclude by discussing the relevance of such a view for contemporary efforts to validate patients' spiritual experiences within mental health care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981488"}
{"pmid": "20981485", "title": "Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites.", "content": "Anti-inflammatory effects of chronic aspirin on brain arachidonic acid metabolites. Pro-inflammatory and anti-inflammatory mediators derived from arachidonic acid (AA) modulate peripheral inflammation and its resolution. Aspirin (ASA) is a unique non-steroidal anti-inflammatory drug, which switches AA metabolism from prostaglandin E₂ (PGE₂) and thromboxane B₂ (TXB₂) to lipoxin A₄ (LXA₄) and 15-epi-LXA₄. However, it is unknown whether chronic therapeutic doses of ASA are anti-inflammatory in the brain. We hypothesized that ASA would dampen increases in brain concentrations of AA metabolites in a rat model of neuroinflammation, produced by a 6-day intracerebroventricular infusion of bacterial lipopolysaccharide (LPS). In rats infused with LPS (0.5 ng/h) and given ASA-free water to drink, concentrations in high-energy microwaved brain of PGE₂, TXB₂ and leukotriene B₄ (LTB₄) were elevated. In rats infused with artificial cerebrospinal fluid, 6 weeks of treatment with a low (10 mg/kg/day) or high (100 mg/kg/day) ASA dose in drinking water decreased brain PGE₂, but increased LTB₄, LXA₄ and 15-epi-LXA₄ concentrations. Both doses attenuated the LPS effects on PGE₂, and TXB₂. The increments in LXA₄ and 15-epi-LXA₄ caused by high-dose ASA were significantly greater in LPS-infused rats. The ability of ASA to increase anti-inflammatory LXA₄ and 15-epi-LXA₄ and reduce pro-inflammatory PGE₂ and TXB₂ suggests considering aspirin further for treating clinical neuroinflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981485"}
{"pmid": "20981490", "title": "Preparation, characterization and in vitro testing of poly(lactic-co-glycolic) acid/barium titanate nanoparticle composites for enhanced cellular proliferation.", "content": "Preparation, characterization and in vitro testing of poly(lactic-co-glycolic) acid/barium titanate nanoparticle composites for enhanced cellular proliferation. The recent advancements in tissue engineering and, more in general, in cell-based applications, has led to an ever increasing interest toward new materials for sustained cell proliferation and differentiation. Here, the preparation and the characterization of scaffolds based on poly(lactic-co-glycolic) acid / barium titanate nanoparticle composites are presented. In vitro testing on H9C2 cell line demonstrates how the presence of the nanoparticles positively affects both the proliferation and the differentiation of this muscle-like cell line. Finally, the possibility to obtain porous scaffold and, therefore, an actual 3D culture system, is introduced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981490"}
{"pmid": "20981492", "title": "Kids' Life and Times: using an Internet survey to measure children's health-related quality of life.", "content": "Kids' Life and Times: using an Internet survey to measure children's health-related quality of life. To examine the psychometric properties of an Internet version of a children and young person's quality of life measure originally designed as a paper questionnaire. Participants were 3,440 children aged 10 and 11 years in Northern Ireland who completed the KIDSCREEN-27 online as part of a general attitudinal survey. The questionnaire was animated using cartoon characters that are familiar to most children and the questions appeared on screen and were read aloud by actors. Exploratory principal component analysis of the online version of the questionnaire supported the existence of five components in line with the paper version. The items loaded on the components that would be expected based on previous findings with five domains--physical well-being, psychological well-being, autonomy and parents, social support and peers, and school environment. Internal consistency reliability of the five domains was measured using Cronbach's alpha, and the results suggested that the scale scores were reliable. The domain scores were similar to those reported in the literature for the paper version. These results suggest that the factor structure and internal consistency reliability scores of the KIDSCREEN-27 embedded within an online survey are comparable to those reported in the literature for the paper version.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981492"}
{"pmid": "20981491", "title": "The Generation R study: a candidate gene study and genome-wide association study (GWAS) on health-related quality of life (HRQOL) of mothers and young children.", "content": "The Generation R study: a candidate gene study and genome-wide association study (GWAS) on health-related quality of life (HRQOL) of mothers and young children. The aim of this paper is to describe the Generation R study as a template that enables candidate gene study and genome-wide association study regarding health-related quality of life (HRQOL) of mothers and their young children. Generation R is a population-based prospective cohort study from fetal life onwards in Rotterdam, The Netherlands. Children were born in 2002-2006. Blood from mothers and placenta cord blood were sampled. Mothers' HRQOL was measured 5 times during pregnancy and after birth using SF-12 and EQ-5D. Children's HRQOL was measured 5 times between age 1 and 5/6 years using Infant-Toddler Quality Of Life questionnaire (ITQOL), Health Status Classification System PreSchool (HSCS-PS) and Child Health Questionnaire Parent Form 28 items (CHQ-PF28), respectively. DNA is available for 8,055 mothers and 5,908 children. Genotyping of various candidate genes and a genome-wide association (GWA) scan (Illumina 610K) of child DNA were done. A template for gene-HRQOL analyses is provided. We start with candidate gene study on HRQOL of mothers and children. Gene-environment interaction and interaction with medical indicators of health status will be explored. Next, GWA study on HRQOL will be performed. Gaining insight into the determinants of HRQOL is essential to assisting efforts in health policy and clinical application to improve well-being and health. In the future, it might be possible to complement HRQOL assessments by examinations of genetic markers. Strengths and weaknesses of the Generation R study are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981491"}
{"pmid": "20981493", "title": "Carotid atheromatic plaque is commonly associated with hypopituitary men.", "content": "Carotid atheromatic plaque is commonly associated with hypopituitary men. Hypopituitarism increases the risks of many cardiovascular conditions and therefore, patients with this disease are more prone to cardiovascular disease. To our knowledge, there have been few studies on carotid artery plaque in male patients with hypopituitarism in assessing cardiovascular risks. The aim of this study was to specifically compare carotid artery plaque while examining other major cardiovascular risk factors between male patients with hypopituitarism and control subjects. Forty male patients aged 30-70 years with hypopituitarism and forty age, sex- matched control subjects were recruited at the Yonsei University Severance Hospital, Seoul, Korea. Carotid intima media thickness (IMT) and atheromatous plaque, anthropometry, lipid profile, and pituitary hormones were assessed. Atheromatous plaque in the carotid arteries was observed more frequently in patients with hypopituitarism than age- and sex-matched control subjects (59.5% vs. 2.5%, P<0.01) without differences of carotid IMTs. Patients with hypopituitarism also exhibited higher waist circumference, waist to hip ratio, total cholesterol and LDL cholesterol than control subjects. In subgroup analysis in male patients with hypopituitarism including GH deficiency, lower testosterone levels were associated with higher waist circumference (r=0.446, P=0.033). In conclusion, hypopituitary males exhibit an increased incidence of carotid artery plaque without differences of carotid IMTs, central obesity and higher total cholesterol level. Lower testosterone levels were associated with central obesity- a strong component of a metabolic syndrome, and unsubstituted testosterone deficiency might be an important cardiovascular risk factor in patients with hypopituitarism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981493"}
{"pmid": "20981494", "title": "Glasgow Prognostic Score is a predictor of perioperative and long-term outcome in patients with only surgically treated esophageal cancer.", "content": "Glasgow Prognostic Score is a predictor of perioperative and long-term outcome in patients with only surgically treated esophageal cancer. Systemic inflammation (SI) plays a pivotal role in cancer. C-reactive protein (CRP) and albumin as parameters of SI form the Glasgow Prognostic Score (GPS). The purpose of the study was to evaluate the potential prognostic role of GPS in a homogeneous population of esophageal cancer (EC) patients undergoing only resection. GPS was evaluated on the basis of admission blood sample taken before surgery. Patients with a CRP < 10 mg/L and albumin > 35 g/L were allocated to GPS0 group. If only CRP was increased or albumin decreased patients were allocated to the GPS1 and patients in whom CRP was ≥10 mg/L and albumin level ≤35 g/L were classified as GPS2. GPS was correlated to clinicopathological parameters and clinical outcome. Increasing GPS significantly correlated with more aggressive tumor biology in terms of tumor size (P < 0.001), presence of regional (P = 0.01) and nonregional lymph node metastasis (P = 0.02), and higher tumor recurrence rate (P < 0.001). Furthermore, GPS was identified as an independent prognosticator of perioperative morbidity (odds ratio 1.9; P = 0.03). In addition, a gradual decrease in disease-free and overall survival was evident between the three GPS subgroups. Survival differences between the GPS groups remained apparent even after stratification of the study population to underlying tumor type and nodal status. GPS was identified as a strong prognosticator of tumor recurrence (hazard ratio 2.5; P < 0.001) and survival (hazard ratio 3.0; P < 0.001) in EC. GPS represents a strong prognosticator of perioperative morbidity and long-term outcome in resected EC patients without neoadjuvant or adjuvant treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981494"}
{"pmid": "20981495", "title": "Single-incision transumbilical laparo-endoscopic gastric benign tumor resection.", "content": "Single-incision transumbilical laparo-endoscopic gastric benign tumor resection. The authors report resection of a gastric benign tumor through single-incision laparoscopy, guided by peroperative gastroscopy. VIDEO: A 25-year-old man consulted after diagnosis of a 40 × 20 cm(2) endoluminal lesion of the gastric cardia. Preoperative work-up showed a stromal tumor with invasion of the muscular layer. The umbilical scar was incised and, after placement of a purse-string suture, an 11-mm nondisposable trocar was inserted for a 10-mm 30° angled scope. Curved and reusable instruments (Karl Storz-Endoskope, Tuttlingen, Germany) and straight ultrasonic shears (Ethicon Endosurgery, Cincinnati, OH, US) were inserted transumbilically. Peroperative gastroscopy located the lesion on the smaller gastric curvature, 1 cm from the gastroesophageal junction. A stitch was placed in the center of the lesion, and gastroscopic grasper helped in maintaining the limits of resection. Gastrostomy was closed using two converting absorbable running sutures. Because of the curves of the instruments there was no conflict between the instruments' tips inside the abdomen (Fig. 1a), or between the surgeon's hands outside the abdomen (Fig. 1b). Leak test with the gastroscope checked the integrity of the suture. The specimen was retrieved transumbilically in a plastic bag. Operative time was 150 min, and the umbilical incision was less than 15 mm. The patient was discharged after 5 days, and he is doing well 3 months postoperatively. Laparoscopic gastric resection can be safely performed through a single-access. Peroperative gastroscopy permits the limits of resection to be precisely determine, and use of curved and reusable instruments allows surgeon to achieve ergonomic conditions as in classic laparoscopy, without increasing the laparoscopic cost.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981495"}
{"pmid": "20981496", "title": "Balancing fertility and oncologic outcomes: can we have our cake and eat it too?", "content": "Balancing fertility and oncologic outcomes: can we have our cake and eat it too?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981496"}
{"pmid": "20981497", "title": "Phylogenetic analysis and inflow route of Tomato yellow leaf curl virus (TYLCV) and Bemisia tabaci in Korea.", "content": "Phylogenetic analysis and inflow route of Tomato yellow leaf curl virus (TYLCV) and Bemisia tabaci in Korea. Tomato yellow leaf curl virus (TYLCV) is a member of the genus Begomovirus of the family Geminiviridae, members of which are characterized by closed circular single-stranded DNA genomes of 2.7-2.8 kb in length, and include viruses transmitted by the Bemisia tabaci whitefly. No reports of TYLCV in Korea are available prior to 2008, after which TYLCV spread rapidly to most regions of the southern Korean peninsula (Gyeongsang-Do, Jeolla-Do and Jeju-Do). Fifty full sequences of TYLCV were analyzed in this study, and the AC1, AV1, IR, and full sequences were analyzed via the muscle program and bayesian analysis. Phylogenetic analysis demonstrated that the Korea TYLCVs were divided into two subgroups. The TYLCV Korea 1 group (Masan) originated from TYLCV Japan (Miyazaki) and the TYLCV Korea 2 group (Jeju/Jeonju) from TYLCV Japan (Tosa/Haruno). A B. tabaci phylogenetic tree was constructed with 16S rRNA and mitochondria cytochrome oxidase I (MtCOI) sequences using the muscle program and MEGA 4.0 in the neighbor-joining algorithm. The sequence data of 16S rRNA revealed that Korea B. tabaci was closely aligned to B. tabaci isolated in Iran and Nigeria. The Q type of B. tabaci, which was originally identified as a viruliferous insect in 2008, was initially isolated in Korea as a non-viruliferous insect in 2005. Therefore, we suggest that two TYLCV Japan isolates were introduced to Korea via different routes, and then transmitted by native B. tabaci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981497"}
{"pmid": "20981498", "title": "Inhibitory effects of ginger (Zingiber officinale Roscoe) essential oil on leukocyte migration in vivo and in vitro.", "content": "Inhibitory effects of ginger (Zingiber officinale Roscoe) essential oil on leukocyte migration in vivo and in vitro. Zingiber officinale Roscoe, popular name ginger, is grown naturally in many parts of the world, including Brazil. Ginger is used in pharmaceutical, cosmetic, and food and beverage industries and the essential oil has been used in folk medicine for manifold conditions including as an analgesic, anti-inflammatory, and antirheumatic. The purpose of this study was to investigate the effects of ginger (Zingiber officinale Roscoe) essential oil (GEO) in an in vitro chemotaxis assay and on leukocyte-endothelial interactions in vivo. GEO was analyzed by GC-MS and the main components identified were ar-curcumene (59%), β-myrcene (14%), 1,8-cineol (8%), citral (7.5%), and zingiberene (7.5%). Oral administration of GEO (200-500 mg/kg) reduced the rolling and leukocyte adherence after 2 h of carrageenan injection (100 μg) into the scrotal chamber. The number of leukocytes migrated to the perivascular tissue 4 h after the irritant stimulus was also diminished. GEO in all doses tested (10(-4), 10(-3), or 10(-2) μL/mL) caused a significant reduction of leukocyte chemotaxis (35.89 ± 4.33, 30.67 ± 0.70, and 35.85 ± 3.83%, respectively) toward casein stimuli. The data presented showed direct and systemic effects of GEO on leukocyte migration as an important mechanism of the anti-inflammatory action of ginger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981498"}
{"pmid": "20981499", "title": "Quantitative analysis of neosalacinol and neokotalanol, another two potent α-glucosidase inhibitors from Salacia species, by LC-MS with ion pair chromatography.", "content": "Quantitative analysis of neosalacinol and neokotalanol, another two potent α-glucosidase inhibitors from Salacia species, by LC-MS with ion pair chromatography. A quantitative analytical method for the highly polar sulfonium pseudo-sugar constituents neosalacinol (3) and neokotalanol (4), another two potent α-glucosidase inhibitors isolated from Ayurvedic traditional medicine Salacia species, was developed by employing an ion pair reagent upon chromatographic separation. The optimum conditions for separation and detection of these two constituents were achieved on an ODS column (3-µm particle size, 2.1-mm i.d. × 100 mm) with 5 mM undecafluorohexanoic acid-MeOH (99:1, v/v) as the mobile phase and using MS equipped with an electrospray ionization source. More than ten samples of Salacia from different origins were analyzed, and the results indicated that the assay was reproducible and precise and could be readily utilized for evaluation of α-glucosidase inhibitory activity of Salacia species. By combining this assay with the quantitative analytical method previously developed for salacinol (1) and kotalanol (2), a more precise and strict evaluation of α-glucosidase inhibitory activities of extracts from Salacia species (R = 0.959 for maltase and 0.795 for sucrase) was achieved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981499"}
{"pmid": "20981500", "title": "On the role of arbitration of discordant double readings of screening mammography: experience from two Italian programmes.", "content": "On the role of arbitration of discordant double readings of screening mammography: experience from two Italian programmes. The authors sought to assess the role of arbitration by a third reader of discordant double readings to reduce the rate of recalls to diagnostic assessment. A consecutive series of 7,660 double readings of screening examinations were considered. Discordant recalls were arbitrated by an expert reader (negative/positive). Diagnostic assessment was performed irrespective of arbitration results, and its outcome was used as reference standard for the study purpose. Assuming that negative arbitration would deny recall, its impact was assessed in terms of reduced recall rate and reduced cancer detection rate. Cost analysis of introducing arbitration was performed according to these results. Recalls at double reading were 528 (6.8%), of which 230 (43.5%) were concordant and 298 (56.5%) were discordant. The latter underwent arbitration, which was negative in 216 (72.4%) and positive in 82 (27.6%) cases, respectively. Overall, 49 cancers were detected (6.39 ‰ screened, 9.2% recalled): 43 cancers were detected among concordant (5.6 ‰ screened, 18.6% concordant) and six among discordant recalls (0.7 ‰ screened, 2.0% discordant). Six cancers were observed among arbitrated cases: five (6%) in positive and one (4.6 ‰) in negative arbitrations. Negative arbitration would have spared 216 assessment procedures (2.8% absolute, 40.9% relative reduction of recall rate) while missing one cancer case (0.13 ‰ absolute, 2.0% relative reduction of cancer detection rate). Arbitration cost was 74 euro, whereas 216 spared assessment procedures would have cost 14,558.4-23,346 euro. Arbitration is a cost-effective procedure that could be employed as a first measure to counterbalance excess recall rate observed in a double-reading scenario.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981500"}
{"pmid": "20981501", "title": "The role of nasoenteric intubation in the MR study of patients with Crohn's disease: our experience and literature review.", "content": "The role of nasoenteric intubation in the MR study of patients with Crohn's disease: our experience and literature review. The aim of this study was to compare magnetic resonance (MR) enteroclysis with MR enterography to verify whether nasoenteric intubation in patients affected by Crohn's disease can provide supplementary information to that afforded by MR study of the small bowel. In a 12-month period, 40 patients (28 women and 12 men, mean age 35 years) affected by Crohn's disease underwent MR imaging. Distension of the small-bowel loops was obtained by administering polyethylene glycol: 15 patients were given the mixture by mouth (MR enterography), whereas the remaining 25 received it via nasoenteric intubation (MR enteroclysis). Our study protocol included morphological sequences taken before and after intravenous injection of contrast medium and real-time functional sequences. Accuracy criteria for the execution of the examinations were designed according to 11 bands. Complete distension of the small-bowel loops was obtained in the 25 patients who underwent MR enteroclysis, with the additional advantage of a suitable assessment of those segments involved in the pathological process. This was not the case for the 15 patients who underwent MR enterography, because both the jejunum and the small-bowel loops appeared partially collapsed. MR enteroclysis is the most effective technique for studying the small bowel in Crohn's disease, as it not only provides a suitable morphological assessment but also supplies functional information.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981501"}
{"pmid": "20981502", "title": "Role of echocardiography and cardiac MRI in depicting morphological and functional imaging findings useful for diagnosing hypertrophic cardiomyopathy.", "content": "Role of echocardiography and cardiac MRI in depicting morphological and functional imaging findings useful for diagnosing hypertrophic cardiomyopathy. Hypertrophic cardiomyopathy (HCM) is a hereditary disease characterised by primary hypertrophy of the left and/or right ventricle. The reference standard for imaging diagnosis is echocardiography. The aim of our study was to prospectively compare the diagnostic accuracy of echocardiography and cardiac magnetic resonance (MR) imaging in patients with HCM. Twenty-two consecutive patients with a known diagnosis of HCM were prospectively evaluated, with echocardiography and cardiac MR imaging performed within 2 weeks of each other (mean interval 7 days, range 2-14 days). Two experienced radiologists blinded to the previous clinical and imaging findings separately reviewed the images. The following parameters were calculated for both techniques: myocardial mass, wall thickness, end-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF), systolic anterior motion (SAM) of the mitral valve and degree of myocardial fibrosis (based on the ultrasonic reflectivity at echocardiography and degree of late enhancement at cardiac MR imaging). The statistical correlation was calculated with Student's t test, Spearman coefficient and Fisher's exact test. A value of p<0.05 was considered significant. The diagnosis of HCM was confirmed in all patients with both techniques, with absolute agreement in terms of the site of disease. The mean value of myocardial mass presented a statistically significant difference between the two techniques (114 g, p<0.001). In contrast, a nonsignificant difference between echocardiography and cardiac MR imaging was found for EDV (102 ml vs 111 ml; p=0.31), ESV (30 ml vs 38 ml; p=0.1), EF (74% vs 68%, p=0.5), SAM (p=0.1) and myocardial fibrosis (p=0.15). Cardiac MR imaging correlates well with echocardiography in defining the morphological and functional parameters useful for the imaging diagnosis of HCM and therefore, in selected cases (poor acoustic window, doubtful echocardiography findings), it may be a valid alternative to echocardiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981502"}
{"pmid": "20981503", "title": "Off-label use of intravascular iodinated organic and MR contrast media.", "content": "Off-label use of intravascular iodinated organic and MR contrast media. This paper analyses off-label prescribing of the iodinated organic and magnetic resonance (MR) contrast media used in diagnostic imaging and evaluates the liability profiles and medicolegal issues associated with such use. The term off-label generally indicates the use of known drugs for which new scientific evidence suggests use in a manner and in clinical scenarios not explicitly addressed by the drug data sheet and is outside the indications for which the medication was approved. In addition, the term also indicates the use of drugs with a different route of administration and dosage from those indicated in the information leaflet. Intravascular contrast media used in diagnostic imaging are drugs in the complete sense of the term, even though they have unique characteristics which in many ways distinguish them from other pharmacological agents. The off-label use of contrast media in diagnostic imaging is a little-investigated field and most commonly, but not exclusively, applies to gadolinium-based contrast media used in MR angiography as well as cardiac and paediatric applications. In particular, the off-label use of contrast media mostly concerns deviations from the recommended dose. As contrast media are to all effects pharmaceutical agents, their off-label use can be considered admissible within the limitations laid down by the Italian law in force (Article 3 of Law 94/98) and its interpretation, i.e. the following criteria must be present: the lack of a valid diagnostic alternative; written informed consent by the patient; the presence of scientific publications validated at the international level; assumption of responsibility by the radiologist. The use of contrast media in modern image-guided medicine is essential. In cases in which the information contained in the information leaflet is modified and updated in any way whatsoever (indications, dosage, at others), specifically if restrictions are introduced in accordance with the law in force, the pharmaceutical industry must provide formal and timely notification to radiologists. On their part as prescribers and users of contrast media, radiologists must remain up to date regarding any changes in indications, dosage and route of administration. Lastly, we propose that the radiology report includes not only the type but also the dose of contrast medium used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981503"}
{"pmid": "20981506", "title": "Editors' overview: topics in the responsible management of research data.", "content": "Editors' overview: topics in the responsible management of research data. Responsible data management is a multifaceted topic involving standards within the research community regarding research design and the sharing of data as well as the collection, selection, analysis and interpretation of data. Transparency in the manipulation of images is increasingly important in order to avoid misrepresentation of research findings, and research oversight is also critical in helping to assure the integrity of the research process. Intellectual property issues both unite and divide academe and industry in their approaches to data management. Central to the realization and promulgation of responsible data management is clear and careful communication of standards and expectations within the research community to trainees as well as among colleagues. These topics are examined and explored in depth in a special issue of Science and Engineering Ethics on responsible data management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981506"}
{"pmid": "20981504", "title": "Dual-source CT coronary angiography: prospective versus retrospective acquisition technique.", "content": "Dual-source CT coronary angiography: prospective versus retrospective acquisition technique. The aim of our work was to compare image quality and radiation dose in a group of patients who underwent cardiac dual-source computed tomography (DSCT) with prospective electrocardiographic (ECG) gating with those of a control group studied with retrospective gating. Sixty patients were randomly assigned to two groups of 30 individuals each. Patients with heart rates >70 bpm and body mass index (BMI) >30 kg/m(2) were excluded. Group A was examined with prospective ECG gating and group B with retrospective gating. The dose-length product (DLP) was recorded to calculate the radiation dose, whereas the effective dose was normalised to a standard 12-cm scan of the heart. Applying the best reconstruction interval, 98.6% of segments in the prospective group and 99.3% in the retrospective group were diagnostic. No significant difference (p>0.05) in image quality was observed between groups. Mean normalised radiation dose was 4.91 ± 0.4 mSv in the prospective-gating group and 14.62 mSv ± 4.36 in the retrospective-gating group (p<0.01). Coronary CT with prospective ECG gating, a standard feature on new scanners, allows for a significant reduction in radiation dose without causing any significant decrease in image quality or in the number of segments assessed. The prospective technique is thus recommended for patients with heart rates £70 bpm and BMI £30 kg/m(2).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981504"}
{"pmid": "20981507", "title": "Binding of heparin to metals.", "content": "Binding of heparin to metals. Heparin is a major prophylactic and treatment agent for thrombosis. Structurally, this anticoagulant is a polydisperse, highly negatively charged polysaccharide mixture that contains a variable density of sulfate group substituents per molecule. Previous study has shown that heparin molecules have a high affinity for a wide range of metal ions with varying oxidation states. However, reports in literature on binding of heparin to metals have investigated only a small sampling of heparin-metal ion interactions. Since interaction of heparin with fluid phase and cell surface macromolecules in vivo is dependent on the heparin structure when bound in a metal ion complex, a survey of the physical parameters for heparin binding to metals is imperative. Atomic absorption and spectrophotometry experiments were performed for metal quantification, and in this study, the relative values for affinity constants and number of binding sites for heparin binding to several alkaline, alkaline earth, main group, and transition metals in their most common oxidation states are reported. We found an overall trend for heparin-metal affinity to be Mn(2+) > Cu(2+) > Ca(2+) > Zn(2+) > Co(2+) > Na(+) > Mg(2+) > Fe(3+) > Ni(2+) > Al(3+)> Sr(2+), with the trend in N (b) being opposite compared with the K (a).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981507"}
{"pmid": "20981505", "title": "Postprandial lipemia detects the effect of soy protein on cardiovascular disease risk compared with the fasting lipid profile.", "content": "Postprandial lipemia detects the effect of soy protein on cardiovascular disease risk compared with the fasting lipid profile. Studies examining the effect of soy protein on cardiovascular disease (CVD) risk factors have not taken advantage of the postprandial state as an adjunct to the fasting lipid profile. The American Heart Association has acknowledged the efficacy of soy protein in reducing CVD risk factors to be limited. We hypothesized that the postprandial state would be more sensitive to any favorable changes associated with consuming soy protein compared with the fasting lipid profile. Furthermore, the presence of isoflavones in soy would enhance this effect. Thirty sedentary males aged 18-30 years were randomly assigned to milk protein (Milk), isoflavone-poor soy (Soy-), or isoflavone-rich soy (Soy+). Usual diets were supplemented with 25 g/day of protein for 28 days. Serum samples were collected before and after supplementation in a fasted state and postprandially at 30, 60, 120, 240, and 360 min after a high-fat, 1,000 kcal shake. Triacylglycerol (TAG), total cholesterol, non-esterified fatty acids, apolipoproteins B-100 and A-I and glucose concentrations were quantified. Fasting concentrations were not different after any protein supplementation. Postprandial TAG and TAG AUC increased after Soy-consumption supporting the postprandial state as a more sensitive indicator of soy ingestion effects on CVD risk factors compared with the fasting lipid profile. Furthermore, the absence of isoflavones in soy protein may have deleterious consequences on purported cardio-protective effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981505"}
{"pmid": "20981508", "title": "Increased ghrelin sensitivity and calorie consumption in subordinate monkeys is affected by short-term astressin B administration.", "content": "Increased ghrelin sensitivity and calorie consumption in subordinate monkeys is affected by short-term astressin B administration. Animals chronically exposed to stressors with access to diets high in fat and sugar consume and prefer these diets, a result consistent with the association between stress and comfort food ingestion in humans. As social subordination in rhesus monkeys provides an ethologically relevant translational model of psychosocial stress, we tested the hypothesis that differences in food intake between dominant and subordinate female monkeys are due to corticotropin-releasing hormone-(CRH) induced alteration in sensitivity to ghrelin, a potent orexigenic signal. We assessed food intake of animals given a choice between a low (LCD) and high calorie diet (HCD) in response to 4-day treatment with the CRH receptor antagonist, astressin B, and to an acute treatment of ghrelin. Ghrelin stimulated intake of LCD in subordinates but did not further increase consumption of HCD, whereas ghrelin decreased LCD consumption without affecting HCD intake in dominant females. Astressin B decreased cortisol levels and increased preference for and intake of the HCD in subordinates and decreased calorie intake and HCD preference in dominant animals. These results suggest that increased caloric intake by subordinates may, in part, be explained by a greater sensitivity to postprandial increases in ghrelin and that CRH receptor antagonism leading to a decrease in cortisol has mixed effects on food choice depending on an individual's stress background.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981508"}
{"pmid": "20981509", "title": "Barth syndrome: an X-linked cardiomyopathy with a novel mutation.", "content": "Barth syndrome: an X-linked cardiomyopathy with a novel mutation. The authors report a 6 yr old boy with Barth syndrome who presented with cardiomyopathy, neutropenia and hypotonia. Urine gas chromatography showed high level of 3-methylglutaconic acid. The DNA of both the patient and the mother showed a heterozygous 3 bp deletion in exon 8 of the tafazzin gene. This abnormality involves the deletion of the bases TGA starting at cDNA nucleotide 891 (c891_893delTGA), resulting in the absence of glutamic acid at codon 202 from a highly conserved area of the tafazzin protein, consistent with the diagnosis of Barth syndrome. This is the first case report of Barth syndrome in Arab population emphasizing the importance of detailed investigations in cases of hereditary cardiomyopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981509"}
{"pmid": "20981510", "title": "Prostate cancer screening.", "content": "Prostate cancer screening. Prostate cancer is the most common cancer and the second leading cause of cancer-related deaths in American men. Although the use of the prostate-specific antigen (PSA) test for prostate cancer screening since the 1990s has led to increased early diagnoses, the most recent studies are in conflict about the risks and benefits of routine prostate cancer screening. Recently, evidence has emerged to support the use of the PSA test to lower mortality, but there is still concern that over-diagnosis may lead to over-treatment of cancers that would not significantly affect patients' health for several years. This article describes the results of important recent prostate cancer screening trials, the National Comprehensive Cancer Network and American Cancer Society screening guidelines, and discusses the implications for clinical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981510"}
{"pmid": "20981511", "title": "C/EBPβ and CHOP participate in tanshinone IIA-induced differentiation and apoptosis of acute promyelocytic leukemia cells in vitro.", "content": "C/EBPβ and CHOP participate in tanshinone IIA-induced differentiation and apoptosis of acute promyelocytic leukemia cells in vitro. Our studies indicated that Tanshinone IIA (TanIIA), which is widely applied in the treatment of cardiovascular diseases with a rare occurrence of side effects, could promote APL cell differentiation and apoptosis. We found TanIIA induced the differentiation of NB4 and MR2 cells with elevated C/EBPβ and CHOP. When C/EBPβ was overexpressed in NB4 cells, the level of CD11b in the transfected cells was significantly elevated. When we used CHOP siRNA to suppress CHOP expression in NB4 cells and then treated these cells with a high concentration of TanIIA, the differentiation and apoptosis of these cells were both significantly increased. These data demonstrate that C/EBPβ is critical for APL cell differentiation and apoptosis induced by TanIIA, and that CHOP acts as a negative regulator of C/EBPβ activity. Our study suggested that TanIIA is a promising drug for treating newly diagnosed and ATRA-resistant APL, and a high concentration of TanIIA associated with inhibition of CHOP, maybe a potentially promising therapy strategy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981511"}
{"pmid": "20981512", "title": "Compartmentalization of the deep cerebellar nuclei based on afferent projections and aldolase C expression.", "content": "Compartmentalization of the deep cerebellar nuclei based on afferent projections and aldolase C expression. The distribution of aldolase C (zebrin II)-positive and -negative Purkinje cells (PCs) can be used to define about 20 longitudinally extended compartments in the cerebellar cortex of the rat, which may correspond to certain aspects of cerebellar functional localization. An equivalent compartmental organization may exist in the deep cerebellar nuclei (DCN). This DCN compartmentalization is primarily represented by the afferent projection pattern in the DCN. PC projections and collateral nuclear projections of olivocerebellar climbing fiber axons have a relatively localized terminal arbor in the DCN. Projections of these axons make a closed olivo-cortico-nuclear circuit to connect a longitudinal stripe-shaped cortical compartment to a small subarea in the DCN, which can be defined as a DCN compartment. The actual DCN compartmentalization, which has been revealed by systematically mapping these projections, is quite different from the cortical compartmentalization. The stripe-shaped alternation of aldolase C-positive and -negative narrow longitudinal compartments in the cerebellar cortex is transformed to the separate clustering of positive and negative compartments in the caudoventral and rostrodorsal DCN, respectively. The distinctive projection of aldolase C-positive and -negative PCs to the caudoventral and rostrodorsal DCN underlies this transformation. Accordingly, the medial cerebellar nucleus is divided into the rostrodorsal aldolase C-negative and caudoventral aldolase C-positive parts. The anterior and posterior interposed nuclei generally correspond to the aldolase C-negative and -positive parts, respectively. DCN compartmentalization is important for understanding functional localization in the DCN since it is speculated that aldolase C-positive and -negative compartments are generally associated with somatosensory and other functions, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981512"}
{"pmid": "20981513", "title": "Controlling Ca2+-activated K+ channels with models of Ca2+ buffering in Purkinje cells.", "content": "Controlling Ca2+-activated K+ channels with models of Ca2+ buffering in Purkinje cells. Intracellular Ca(2+) concentrations play a crucial role in the physiological interaction between Ca(2+) channels and Ca(2+)-activated K(+) channels. The commonly used model, a Ca(2+) pool with a short relaxation time, fails to simulate interactions occurring at multiple time scales. On the other hand, detailed computational models including various Ca(2+) buffers and pumps can result in large computational cost due to radial diffusion in large compartments, which may be undesirable when simulating morphologically detailed Purkinje cell models. We present a method using a compensating mechanism to replace radial diffusion and compared the dynamics of different Ca(2+) buffering models during generation of a dendritic Ca(2+) spike in a single compartment model of a PC dendritic segment with Ca(2+) channels of P- and T-type and Ca(2+)-activated K(+) channels of BK- and SK-type. The Ca(2+) dynamics models used are (1) a single Ca(2+) pool; (2) two Ca(2+) pools, respectively, for the fast and slow transients; (3) detailed Ca(2+) dynamics with buffers, pump, and diffusion; and (4) detailed Ca(2+) dynamics with buffers, pump, and diffusion compensation. Our results show that detailed Ca(2+) dynamics models have significantly better control over Ca(2+)-activated K(+) channels and lead to physiologically more realistic simulations of Ca(2+) spikes and bursting. Furthermore, the compensating mechanism largely eliminates the effect of removing diffusion from the model on Ca(2+) dynamics over multiple time scales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981513"}
{"pmid": "20981517", "title": "Chemoinformatics and library design.", "content": "Chemoinformatics and library design. This chapter provides a brief overview of chemoinformatics and its applications to chemical library design. It is meant to be a quick starter and to serve as an invitation to readers for more in-depth exploration of the field. The topics covered in this chapter are chemical representation, chemical data and data mining, molecular descriptors, chemical space and dimension reduction, quantitative structure-activity relationship, similarity, diversity, and multiobjective optimization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981517"}
{"pmid": "20981515", "title": "Polymorphisms in the 5'- and 3'-untranslated region of the VEGF gene and sporadic breast cancer risk and clinicopathologic characteristics.", "content": "Polymorphisms in the 5'- and 3'-untranslated region of the VEGF gene and sporadic breast cancer risk and clinicopathologic characteristics. The wild and the variant alleles of the C936T and G634C vascular endothelial grow factor (VEGF) polymorphisms seem to be linked to higher angiogenic phenotype than the remaining alleles and may act on breast cancer (BC) origin. We investigated the influence of the VEGF C936T and G634C polymorphisms on the occurrence and clinicopathologic characteristics of sporadic breast cancer (SBC) in 235 patients and 235 controls. Peripheral blood samples of all individuals were analysed by the polymerase chain reaction for identification of genotypes and by enzyme-linked immunosorbent assay (ELISA) for quantification of serum VEGF levels. The variant 634CC genotype isolated (16.2% versus 10.7%, P  = 0.01) and in combination with the wild 936CC genotype (10.6% versus 5.5%, P  = 0.01) were more common in patients than in controls. The carriers of the respective genotypes were under a 2.20-fold and a 3.08-fold increased risks for the disease. Additionally, the frequency of the wild 936CC genotype was higher in patients with tumours of histological grade III compared to those with tumours of I+II histological grades (84.0% versus 64.7%, P  = 0.004) and in patients with positive oestrogen receptor tumours compared to those with tumours lacking oestrogen receptor expression (84.7% versus 73.9%, P  = 0.02). Similar serum values of VEGF were seen in patients and controls with the distinct genotypes of the VEGF. The data suggest that the VEGF wild 936CC and the variant 634CC genotypes constitute inherited determinants of SBC and SBC aggressiveness in Brazil, but are not significant predictors of circulating VEGF levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981515"}
{"pmid": "20981516", "title": "Historical overview of chemical library design.", "content": "Historical overview of chemical library design. High-throughput chemistry (HTC) is approaching its 20-year anniversary. Since 1992, some 5,000 chemical libraries, prepared for the purpose of biological investigation and drug discovery, have been published in the scientific literature. This review highlights the key events in the history of HTC with emphasis on library design. A historical perspective on the design of screening, targeted, and optimization libraries and their application is presented. Design strategies pioneered in the 1990s remain viable in the twenty-first century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981516"}
{"pmid": "20981514", "title": "Biological functions of microRNAs: a review.", "content": "Biological functions of microRNAs: a review. MicroRNAs (miRNAs) are a recently discovered family of endogenous, noncoding RNA molecules approximately 22 nt in length. miRNAs modulate gene expression post-transcriptionally by binding to complementary sequences in the coding or 3' untranslated region of target messenger RNAs (mRNAs). It is now clear that the biogenesis and function of miRNAs are related to the molecular mechanisms of various clinical diseases, and that they can potentially regulate every aspect of cellular activity, including differentiation and development, metabolism, proliferation, apoptotic cell death, viral infection and tumorgenesis. Here, we review recent advances in miRNA research, and discuss the diverse roles of miRNAs in disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981514"}
{"pmid": "20981519", "title": "A scalable approach to combinatorial library design.", "content": "A scalable approach to combinatorial library design. In this chapter, we describe an algorithm for the design of lead-generation libraries required in combinatorial drug discovery. This algorithm addresses simultaneously the two key criteria of diversity and representativeness of compounds in the resulting library and is computationally efficient when applied to a large class of lead-generation design problems. At the same time, additional constraints on experimental resources are also incorporated in the framework presented in this chapter. A computationally efficient scalable algorithm is developed, where the ability of the deterministic annealing algorithm to identify clusters is exploited to truncate computations over the entire dataset to computations over individual clusters. An analysis of this algorithm quantifies the trade-off between the error due to truncation and computational effort. Results applied on test datasets corroborate the analysis and show improvement by factors as large as ten or more depending on the datasets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981519"}
{"pmid": "20981518", "title": "Molecular library design using multi-objective optimization methods.", "content": "Molecular library design using multi-objective optimization methods. Advancements in combinatorial chemistry and high-throughput screening technology have enabled the synthesis and screening of large molecular libraries for the purposes of drug discovery. Contrary to initial expectations, the increase in screening library size, typically combined with an emphasis on compound structural diversity, did not result in a comparable increase in the number of promising hits found. In an effort to improve the likelihood of discovering hits with greater optimization potential, more recent approaches attempt to incorporate additional knowledge to the library design process to effectively guide the search. Multi-objective optimization methods capable of taking into account several chemical and biological criteria have been used to design collections of compounds satisfying simultaneously multiple pharmaceutically relevant objectives. In this chapter, we present our efforts to implement a multi-objective optimization method, MEGALib, custom-designed to the library design problem. The method exploits existing knowledge, e.g. from previous biological screening experiments, to identify and profile molecular fragments used subsequently to design compounds compromising the various objectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981518"}
{"pmid": "20981520", "title": "Application of Free-Wilson selectivity analysis for combinatorial library design.", "content": "Application of Free-Wilson selectivity analysis for combinatorial library design. In this chapter we present an application of in silico quantitative structure-activity relationship (QSAR) models to establish a new ligand-based computational approach for generating virtual libraries. The Free-Wilson methodology was applied to extract rules from two data sets containing compounds which were screened against either kinase or PDE gene family panels. The rules were used to make predictions for all compounds enumerated from their respective virtual libraries. We also demonstrate the construction of R-group selectivity profiles by deriving activity contributions against each protein target using the QSAR models. Such selectivity profiles were used together with protein structural information from X-ray data to provide a better understanding of the subtle selectivity relationships between kinase and PDE family members.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981520"}
{"pmid": "20981521", "title": "Application of QSAR and shape pharmacophore modeling approaches for targeted chemical library design.", "content": "Application of QSAR and shape pharmacophore modeling approaches for targeted chemical library design. Optimization of chemical library composition affords more efficient identification of hits from biological screening experiments. The optimization could be achieved through rational selection of reagents used in combinatorial library synthesis. However, with a rapid advent of parallel synthesis methods and availability of millions of compounds synthesized by many vendors, it may be more efficient to design targeted libraries by means of virtual screening of commercial compound collections. This chapter reviews the application of advanced cheminformatics approaches such as quantitative structure-activity relationships (QSAR) and pharmacophore modeling (both ligand and structure based) for virtual screening. Both approaches rely on empirical SAR data to build models; thus, the emphasis is placed on achieving models of the highest rigor and external predictive power. We present several examples of successful applications of both approaches for virtual screening to illustrate their utility. We suggest that the expert use of both QSAR and pharmacophore models, either independently or in combination, enables users to achieve targeted libraries enriched with experimentally confirmed hit compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981521"}
{"pmid": "20981522", "title": "Combinatorial library design from reagent pharmacophore fingerprints.", "content": "Combinatorial library design from reagent pharmacophore fingerprints. Combinatorial and parallel chemical synthesis technologies are powerful tools in early drug discovery projects. Over the past couple of years an increased emphasis on targeted lead generation libraries and focussed screening libraries in the pharmaceutical industry has driven a surge in computational methods to explore molecular frameworks to establish new chemical equity. In this chapter we describe a complementary technique in the library design process, termed ProSAR, to effectively cover the accessible pharmacophore space around a given scaffold. With this method reagents are selected such that each R-group on the scaffold has an optimal coverage of pharmacophoric features. This is achieved by optimising the Shannon entropy, i.e. the information content, of the topological pharmacophore distribution for the reagents. As this method enumerates compounds with a systematic variation of user-defined pharmacophores to the attachment point on the scaffold, the enumerated compounds may serve as a good starting point for deriving a structure-activity relationship (SAR).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981522"}
{"pmid": "20981523", "title": "Docking methods for structure-based library design.", "content": "Docking methods for structure-based library design. The drug discovery process mainly relies on the experimental high-throughput screening of huge compound libraries in their pursuit of new active compounds. However, spiraling research and development costs and unimpressive success rates have driven the development of more rational, efficient, and cost-effective methods. With the increasing availability of protein structural information, advancement in computational algorithms, and faster computing resources, in silico docking-based methods are increasingly used to design smaller and focused compound libraries in order to reduce screening efforts and costs and at the same time identify active compounds with a better chance of progressing through the optimization stages. This chapter is a primer on the various docking-based methods developed for the purpose of structure-based library design. Our aim is to elucidate some basic terms related to the docking technique and explain the methodology behind several docking-based library design methods. This chapter also aims to guide the novice computational practitioner by laying out the general steps involved for such an exercise. Selected successful case studies conclude this chapter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981523"}
{"pmid": "20981526", "title": "Design of screening collections for successful fragment-based lead discovery.", "content": "Design of screening collections for successful fragment-based lead discovery. A successful fragment-based lead discovery (FBLD) campaign largely depends on the content of the fragment collection being screened. To design a successful fragment collection, several factors must be considered, including collection size, property filters, hit follow-up considerations, and screening methods. In this chapter, we will discuss each factor and how it was applied to the design and assembly of one or more fragment collections in a major pharmaceutical company setting. We will also present examples and statistics of screening results from such collections and how subsequent collections can be improved. Lastly, we will provide a summary comparison of selected fragment collections from literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981526"}
{"pmid": "20981524", "title": "Structure-based library design in efficient discovery of novel inhibitors.", "content": "Structure-based library design in efficient discovery of novel inhibitors. Structure-based library design employs both structure-based drug design (SBDD) and combinatorial library design. Combinatorial library design concepts have evolved over the past decade, and this chapter covers several novel aspects of structure-based library design together with successful case studies in the anti-viral drug design HCV target area. Discussions include reagent selections, diversity library designs, virtual screening, scoring/ranking, and post-docking pose filtering, in addition to the considerations of chemistry synthesis. Validation criteria for a successful design include an X-ray co-crystal complex structure, in vitro biological data, and the number of compounds to be made, and these are addressed in this chapter as well.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981524"}
{"pmid": "20981525", "title": "Structure-based and property-compliant library design of 11β-HSD1 adamantyl amide inhibitors.", "content": "Structure-based and property-compliant library design of 11β-HSD1 adamantyl amide inhibitors. Multiproperty lead optimization that satisfies multiple biological endpoints remains a challenge in the pursuit of viable drug candidates. Optimization of a given lead compound to one having a desired set of molecular attributes often involves a lengthy iterative process that utilizes existing information, tests hypotheses, and incorporates new data. Within the context of a data-rich corporate setting, computational tools and predictive models have provided the chemists a means for facilitating and streamlining this iterative design process. This chapter discloses an actual library design scenario for following up a lead compound that inhibits 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme. The application of computational tools and predictive models in the targeted library design of adamantyl amide 11β-HSD1 inhibitors is described. Specifically, the multiproperty profiling using our proprietary PGVL (Pfizer Global Virtual Library) Hub is discussed in conjunction with the structure-based component of the library design using our in-house docking tool AGDOCK. The docking simulations were based on a piecewise linear potential energy function in combination with an efficient evolutionary programming search engine. The library production protocols and results are also presented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981525"}
{"pmid": "20981527", "title": "Fragment-based drug design.", "content": "Fragment-based drug design. Fragment-based drug design (FBDD), which is comprised of both fragment screening and the use of fragment hits to design leads, began more than 15 years ago and has been steadily gaining in popularity and utility. Its origin lies on the fact that the coverage of chemical space and the binding efficiency of hits are directly related to the size of the compounds screened. Nevertheless, FBDD still faces challenges, among them developing fragment screening libraries that ensure optimal coverage of chemical space, physical properties and chemical tractability. Fragment screening also requires sensitive assays, often biophysical in nature, to detect weak binders. In this chapter we will introduce the technologies used to address these challenges and outline the experimental advantages that make FBDD one of the most popular new hit-to-lead process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981527"}
{"pmid": "20981529", "title": "The design, annotation, and application of a kinase-targeted library.", "content": "The design, annotation, and application of a kinase-targeted library. We present here a workflow for designing a kinase-targeted library (KTL) with the goal of capturing known kinase inhibitor chemical space. We validated our design retrospectively using recent, high-throughput screening data and found significant enrichment of kinase inhibitor hits while retaining majority of the active kinase inhibitor series. To further assist kinase projects in triaging KTL screen hits, we also developed a methodology to systematically annotate known kinase inhibitors in the KTL with regard to their binding modes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981529"}
{"pmid": "20981528", "title": "LEAP into the Pfizer Global Virtual Library (PGVL) space: creation of readily synthesizable design ideas automatically.", "content": "LEAP into the Pfizer Global Virtual Library (PGVL) space: creation of readily synthesizable design ideas automatically. Pfizer Global Virtual Library (PGVL) of 10(13) readily synthesizable molecules offers a tremendous opportunity for lead optimization and scaffold hopping in drug discovery projects. However, mining into a chemical space of this size presents a challenge for the concomitant design informatics due to the fact that standard molecular similarity searches against a collection of explicit molecules cannot be utilized, since no chemical information system could create and manage more than 10(8) explicit molecules. Nevertheless, by accepting a tolerable level of false negatives in search results, we were able to bypass the need for full 10(13) enumeration and enabled the efficient similarity search and retrieval into this huge chemical space for practical usage by medicinal chemists. In this report, two search methods (LEAP1 and LEAP2) are presented. The first method uses PGVL reaction knowledge to disassemble the incoming search query molecule into a set of reactants and then uses reactant-level similarities into actual available starting materials to focus on a much smaller sub-region of the full virtual library compound space. This sub-region is then explicitly enumerated and searched via a standard similarity method using the original query molecule. The second method uses a fuzzy mapping onto candidate reactions and does not require exact disassembly of the incoming query molecule. Instead Basis Products (or capped reactants) are mapped into the query molecule and the resultant asymmetric similarity scores are used to prioritize the corresponding reactions and reactant sets. All sets of Basis Products are inherently indexed to specific reactions and specific starting materials. This again allows focusing on a much smaller sub-region for explicit enumeration and subsequent standard product-level similarity search. A set of validation studies were conducted. The results have shown that the level of false negatives for the disassembly-based method is acceptable when the query molecule can be recognized for exact disassembly, and the fuzzy reaction mapping method based on Basis Products has an even better performance in terms of lower false-negative rate because it is not limited by the requirement that the query molecule needs to be recognized by any disassembly algorithm. Both search methods have been implemented and accessed through a powerful desktop molecular design tool (see ref. (33) for details). The chapter will end with a comparison of published search methods against large virtual chemical space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981528"}
{"pmid": "20981530", "title": "PGVL Hub: An integrated desktop tool for medicinal chemists to streamline design and synthesis of chemical libraries and singleton compounds.", "content": "PGVL Hub: An integrated desktop tool for medicinal chemists to streamline design and synthesis of chemical libraries and singleton compounds. PGVL Hub is an integrated molecular design desktop tool that has been developed and globally deployed throughout Pfizer discovery research units to streamline the design and synthesis of combinatorial libraries and singleton compounds. This tool supports various workflows for design of singletons, combinatorial libraries, and Markush exemplification. It also leverages the proprietary PGVL virtual space (which contains 10(14) molecules spanned by experimentally derived synthesis protocols and suitable reactants) for lead idea generation, lead hopping, and library design. There had been an intense focus on ease of use, good performance and robustness, and synergy with existing desktop tools such as ISIS/Draw and SpotFire. In this chapter we describe the three-tier enterprise software architecture, key data structures that enable a wide variety of design scenarios and workflows, major technical challenges encountered and solved, and lessons learned during its development and deployment throughout its production cycles. In addition, PGVL Hub represents an extendable and enabling platform to support future innovations in library and singleton compound design while being a proven channel to deliver those innovations to medicinal chemists on a global scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981530"}
{"pmid": "20981532", "title": "GLARE: A tool for product-oriented design of combinatorial libraries.", "content": "GLARE: A tool for product-oriented design of combinatorial libraries. Combinatorial chemistry with two or more diversity points often leads to an immense number of theoretical products. It is sensible to select the reagents based on the desired properties of the products in the hope of maximizing the usefulness of the synthesized molecules. The presented tool enables the filtering of reagents such that any further reagent selection will form products matching the desired properties. Virtual combinatorial library leading to thousands of billions of products can be rapidly assessed. The publicly available software ( http://glare.sourceforge.net ) and key algorithmic elements are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981532"}
{"pmid": "20981533", "title": "CLEVER: A general design tool for combinatorial libraries.", "content": "CLEVER: A general design tool for combinatorial libraries. CLEVER is a computational tool designed to support the creation, manipulation, enumeration, and visualization of combinatorial libraries. The system also provides a summary of the diversity, coverage, and distribution of selected compound collections. When deployed in conjunction with large-scale virtual screening campaigns, CLEVER can offer insights into what chemical compounds to synthesize, and, more importantly, what not to synthesize. In this chapter, we describe how CLEVER is used and offer advice in interpreting the results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981533"}
{"pmid": "20981531", "title": "Design of targeted libraries against the human Chk1 kinase using PGVL Hub.", "content": "Design of targeted libraries against the human Chk1 kinase using PGVL Hub. PGVL Hub is a Pfizer internal desktop tool for chemical library and singleton design. In this chapter, we give a short introduction to PGVL Hub, the core workflow it supports, and the rich design capabilities it provides. By re-creating two legacy targeted libraries against the human checkpoint kinase 1 (Chk1) as a showcase, we illustrate how PGVL Hub could be used to help library designers carry out the steps in library design and realize design objectives such as SAR expansion and improvement in both kinase selectivity and compound aqueous solubility. Finally we share several tips about library design and usage of PGVL Hub.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981531"}
{"pmid": "20981534", "title": "Male behaviors reveal multiple pherotypes within vine mealybug Planococcus ficus (Signoret) (Hemiptera; Pseudococcidae) populations.", "content": "Male behaviors reveal multiple pherotypes within vine mealybug Planococcus ficus (Signoret) (Hemiptera; Pseudococcidae) populations. The vine mealybug (VM) females collected in Israel produce two sex pheromone compounds: lavandulyl senecioate (LS) and (S)-lavandulyl isovalerate (LI). The males display ambiguous behavior to LI: repulsion in the vineyard and attraction of laboratory-reared males. We addressed the question of individual male behavior, i.e., do males respond to both LS and LI, or might they display a distinct response to each of the two pheromone compounds. We compared male pherotype frequencies between wild-caught and laboratory-reared populations. Then, we examined the relationship between pherotype composition and male capture rates in pheromone traps. Finally, we addressed the heredity of the pherotypes. The Israeli VM populations contain nine different male pherotypes, as defined according to the male behavior to pheromone compounds. The studied Portuguese populations included five of the nine pherotypes; none of the Portuguese males were attracted to LI. It seems that the high frequency of males that were attracted to LI is related to dense VM populations. It is hypothesized that selection for the male pherotypes, I males, those that respond to LI, occur under high-density rearing conditions. This may result from shorter development times of males and females that produce more I male pherotypes. The lower relative frequency of trapping of males in LI-baited traps than expected from the percentage determined in a Petri dish arena suggests that males that respond solely to LS (S males) are better fliers. The results also suggest that the pherotype trait is inherited by both sexes of the VM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981534"}
{"pmid": "20981535", "title": "Blood exposure has a negative effect on engineered cartilage.", "content": "Blood exposure has a negative effect on engineered cartilage. The aim of this study was to investigate the in vitro effect of different concentrations of blood on the morphological and biochemical properties of engineered cartilage. Previous studies have demonstrated a negative effect of blood on native cartilage; however, the effect of the contact of blood on engineered cartilage is unclear. Articular chondrocytes were isolated from swine joints, expanded in monolayer culture, and seeded onto collagen membranes. The seeded membranes were cultured for 3 days in the presence of different concentrations of peripheral blood. Some samples were retrieved at the end of the blood contact, others after 21 additional days of standard culture conditions, in order to investigate the \"long-term effect\" of the blood contact. All seeded samples showed an increase in the weight and an evident cartilage-like matrix production. A concentration-dependent reduction in the mitochondrial activity due to blood contact was shown at the earlier culture time, followed by a partial recover at the longer culture time. A blood contact of 3 days affected the chondrocytes' activity and determined a delay in the maturation of the engineered cartilage. These findings have clinical relevance, as autologous chondrocytes seeded onto biological scaffolds has become an established surgical method for articular cartilage repair. Therefore, further investigation into material sciences should be encouraged for the development of scaffold protecting the reparative cells from the blood insult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981535"}
{"pmid": "20981537", "title": "Study of behaviour on simulated daylight ageing of artists' acrylic and poly(vinyl acetate) paint films.", "content": "Study of behaviour on simulated daylight ageing of artists' acrylic and poly(vinyl acetate) paint films. This work proposes a multi-method approach that combines advanced microscopy (SEM/EDX, AFM) and spectroscopy (UV-vis and FTIR) techniques. This approach not only characterises the behaviour of the additives of two commercial poly(vinyl acetate) (PVAc) and acrylic emulsion paints but also simultaneously characterises the changes in chemical composition and morphology observed in the paint films as a result of ageing due to the paints being exposed to an intense source of simulated daylight. In parallel, a series of mechanical tests were performed that correlate the chemical changes in composition and the changes observed in the films' mechanical properties. This work was a comparative study between both types of acrylic and PVAc paints. The results obtained are of great interest for the modern paint conservation field as they provide valuable information on the mid- and long-term behaviours of these synthetic paints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981537"}
{"pmid": "20981536", "title": "Muscle biopsies from the supraspinatus in retracted rotator cuff tears respond normally to passive mechanical testing: a pilot study.", "content": "Muscle biopsies from the supraspinatus in retracted rotator cuff tears respond normally to passive mechanical testing: a pilot study. The aim of the present study was to assess the function of the isolated muscle component in retracted rotator cuff tears. Muscle biopsies were harvested from the supraspinatus and the ipsilateral deltoid in seven patients undergoing surgery for a large, retracted rotator cuff tear. Single fibres and fibre bundles were subjected to passive stretching in vitro with subsequent recordings of tension and sarcomere lengths using the laser diffraction technique. Stress-strain curves were plotted, and the elastic modulus was calculated for all preparations. Morphology was evaluated with regard to collagen fraction, ratio between fast and slow fibres, fibre size and fibre size variability using standard staining techniques. Intra-individual comparisons of the stress-strain curves showed a high degree of conformity in terms of both shape and tangent values, and there were no statistically significant differences in the elastic modulus for single fibres and bundles in the deltoid and supraspinatus muscles, respectively, supported by the analysis of the observed confidence interval of the differences between the paired values of the elastic modulus. There were no differences in collagen content, fibre size and ratio between fast and slow fibres in the deltoid and supraspinatus muscles, respectively. We conclude that muscle biopsies from the supraspinatus in retracted rotator cuff tears respond normally to mechanical testing in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981536"}
{"pmid": "20981538", "title": "Wrist muscle activation, interaction torque and mechanical properties in unskilled throws of different speeds.", "content": "Wrist muscle activation, interaction torque and mechanical properties in unskilled throws of different speeds. An unexpected property of unskilled overarm throws is that wrist flexion velocity at ball release does not increase in throws of increasing speed. We investigated the nature of the interaction torques and wrist mechanical properties that have been proposed to produce this property. Twelve recreational throwers made seated 2-D throws, which were used as a model for unskilled throwing. Joint motions were computed from recordings made with search coils; joint torques were calculated from inverse dynamics. Wrist flexion velocity at ball release was actually smaller in fast throws than in slow throws. This was associated in fast throws with the decrease in a large wrist flexor muscle torque (i.e., a calculated residual torque) in the last 40 ms before ball release, and its reversal to an extensor torque. Consequently, wrist flexor muscle torque was unable to oppose a small maintained wrist extensor interaction torque that arose from continuing elbow extension acceleration. The decrease in wrist flexor muscle torque was not associated with a decrease in wrist flexor EMG activity, nor with an increase in wrist extensor EMG activity. These findings support the hypothesis that the smaller wrist flexion velocity at ball release in fast 2-D throws results from a wrist extensor interaction torque and from a large wrist extensor viscoelastic torque. We propose that in fast 3-D throws skilled subjects decelerate elbow extension before ball release to help overcome these wrist extensor torques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981538"}
{"pmid": "20981539", "title": "Surface texture can bias tactile form perception.", "content": "Surface texture can bias tactile form perception. The sense of touch is believed to provide a reliable perception of the object's properties; however, our tactile perceptions could be illusory at times. A recently reported tactile illusion shows that a raised form can be perceived as indented when it is surrounded by textured areas. This phenomenon suggests that the form perception can be influenced by the surface textures in its adjacent areas. As perception of texture and that of form have been studied independently of each other, the present study examined whether textures, in addition to the geometric edges, contribute to the tactile form perception. We examined the perception of the flat and raised contact surface (3.0 mm width) with various heights (0.1, 0.2, 0.3 mm), which had either textured or non-textured adjacent areas, under the static, passive and active touch conditions. Our results showed that texture decreased the raised perception of the surface with a small height (0.1 mm) and decreased the flat perception of the physically flat surface under the passive and active touch conditions. We discuss a possible mechanism underlying the effect of the textures on the form perception based on previous neurophysiological findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981539"}
{"pmid": "20981541", "title": "Automatic movement error detection and correction processes in reaching movements.", "content": "Automatic movement error detection and correction processes in reaching movements. Manual aiming movements can be amended during their execution. Recent evidence suggests that error detection and correction are based on automatic and even reflexive processing of afferent information. In this study, we wanted to determine whether these processes are affected by the occurrence of successive events requiring adjustments of the originally planned movement. To reach our goal, we used a video-aiming task. For a small proportion of the trials, the cursor moved by the participant was translated laterally by 15 mm (cursor jump) soon after movement initiation. For some of the cursor-jump trials, a second cursor jump occurred 100 ms after the first one and canceled or doubled the initial cursor translation. Results showed that participants were able to cancel or double the size of the correction in response to the second cursor jump. More importantly, in double-jump trials, the correction latency for the first and second cursor jumps did not differ from that of single-jump trials. Moreover, the correction for the second cursor jump blended seamlessly with the correction for the first cursor jump. These observations suggest that the processes leading of a correction for a cursor jump do not interfere with incoming visual information.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981541"}
{"pmid": "20981540", "title": "Temporal evolution of the phase correction response in synchronization of taps with perturbed two-interval rhythms.", "content": "Temporal evolution of the phase correction response in synchronization of taps with perturbed two-interval rhythms. Human sensorimotor synchronization is flexible but subject to temporal constraints. Previous research has shown that musicians tend to lose synchrony with target tones in an isochronous sequence when the sequence rate exceeds 8-10 Hz, presumably because phase correction ceases to function. The present study investigated directly the time required for an immediate phase correction response (PCR). Musicians tapped in synchrony with cyclic two-interval (short-long) rhythms, using the two hands in alternation. Perturbations were applied to the long interval, and the compensatory shift of the next tap (the PCR) was measured following the short interval, whose duration was varied from 100 to 300 ms. The PCR was found to increase gradually within this range, being nearly absent at 100 ms. Similar results were obtained when participants tapped only with the second tone in each rhythmic group, which confirms that the PCR is based on the preceding tone rather than on the preceding tap-tone asynchrony, and also when the second tone was omitted in the pacing sequence, which indicates that the PCR occurs automatically even when there is no synchronization target for the critical tap. These results extend earlier findings regarding rate limits of synchronization and also provide further support for an event-based phase resetting account of the PCR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981540"}
{"pmid": "20981542", "title": "Three generations of hereditary long-QT syndrome with complete penetrance caused by the p.G316E KCNQ1 mutation.", "content": "Three generations of hereditary long-QT syndrome with complete penetrance caused by the p.G316E KCNQ1 mutation. This report describes a three-generation family with a severe phenotype of long-QT syndrome-1 (LQTS-1) caused by a single nucleotide mutation in the KQT-like, voltage-gated potassium channel-1 gene (KCNQ1; MIM 607542). Two members of the family died suddenly in their childhood, and all eight surviving members with prolonged QT have a heterozygous missense mutation resulting in a glycine-to-glutamate amino acid substitution at position 316 of the potassium channel. In this family, the newly reported mutation, guanine-to-adenosine at position 947 in the KCNQ1 gene, exhibits a dominant trait of LQTS with complete penetrance, in contrast to the relatively reduced clinical penetrance found in most LQTS cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981542"}
{"pmid": "20981543", "title": "Simultaneous resection of primary colorectal cancer and synchronous liver metastases.", "content": "Simultaneous resection of primary colorectal cancer and synchronous liver metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981543"}
{"pmid": "20981544", "title": "Parathyroid carcinoma encountered after minimally invasive focused parathyroidectomy may not require further radical surgery.", "content": "Parathyroid carcinoma encountered after minimally invasive focused parathyroidectomy may not require further radical surgery. Parathyroid carcinoma accounts for <1% of tumors in primary hyperparathyroidism (PHPT). Distinguishing parathyroid malignancy from benign disease is difficult both before and after initial surgery. Despite the improved specificity of a malignant diagnosis with immunohistochemistry for parafibromin and PGP9.5, proven metastatic behavior remains the gold standard of diagnosis. Minimally invasive focused parathyroidectomy (MIP) is widely performed in patients with PHPT and positive localization studies; thus, it is inevitable that some parathyroid carcinomas will be encountered at MIP. We present our experience of this rare entity. The present study represents a surgical case series of patients with parathyroid carcinoma encountered after MIP. The clinicopathological features of benign and malignant parathyroid tumors were compared. Multiple regression analysis was undertaken to compare indicators of malignancy. Between May 1999 and April 2010, a total of 1,292 patients underwent MIP at the University of Sydney Endocrine Surgical Unit, and a histopathological diagnosis of parathyroid carcinoma was made in seven patients (0.5%). Staining for parafibromin and/or PGP9.5 was abnormal in five carcinomas (71%). Despite subsequent unilateral thyroid lobectomy and lymphadenectomy in six patients, no further malignancy was identified in any specimens. Compared to controls, preoperative calcium (p = 0.04) and parathyroid hormone (p = 0.01) were significantly higher in patients with malignancy. The positive predictive value of these parameters for carcinoma was 56 and 75%, respectively. In patients diagnosed with parathyroid carcinoma after MIP where preoperative imaging had already demonstrated localized disease, revision en bloc surgery did not reveal any residual disease. The benefits of further radical surgery for parathyroid carcinoma after MIP remain controversial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981544"}
{"pmid": "20981546", "title": "Caldicoprobacter algeriensis sp. nov. a new thermophilic anaerobic, xylanolytic bacterium isolated from an Algerian hot spring.", "content": "Caldicoprobacter algeriensis sp. nov. a new thermophilic anaerobic, xylanolytic bacterium isolated from an Algerian hot spring. A thermophilic anaerobic bacterium (strain TH7C1(T)) was isolated from the hydrothermal hot spring of Guelma in the northeast of Algeria. Strain TH7C1(T) stained Gram-positive, was a non-motile rod appearing singly, in pairs, or as long chains (0.7-1 × 2-6 μm(2)). Spores were never observed. It grew at temperatures between 55 and 75°C (optimum 65°C) and at pH between 6.2 and 8.3 (optimum 6.9). It did not require NaCl for growth, but tolerated it up to 5 g l(-1). Strain TH7C1(T) is an obligatory heterotroph fermenting sugars including glucose, galactose, lactose, raffinose, fructose, ribose, xylose, arabinose, maltose, mannitol, cellobiose, mannose, melibiose, saccharose, but also xylan, and pyruvate. Fermentation of sugars only occurred in the presence of yeast extract (0.1%). The end-products from glucose fermentation were acetate, lactate, ethanol, CO(2), and H(2). Nitrate, nitrite, thiosulfate, elemental sulfur, sulfate, and sulfite were not used as electron acceptors. The G+C content of the genomic DNA was 44.7 mol% (HPLC techniques). Phylogenetic analysis of the small-subunit ribosomal RNA (rRNA) gene sequence indicated that strain TH7C1(T) was affiliated to Firmicutes, order Clostridiales, family Caldicoprobacteraceae, with Caldicoprobacter oshimai (98.5%) being its closest relative. Based on phenotypic, phylogenetic, and genetic characteristics, strain TH7C1(T) is proposed as a novel species of genus Caldicoprobacter, Caldicoprobacter algeriensis, sp. nov. (strain TH7C1(T) = DSM 22661(T) = JCM 16184(T)).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981546"}
{"pmid": "20981547", "title": "Temperature affects sole carbon utilization patterns of Campylobacter coli 49941.", "content": "Temperature affects sole carbon utilization patterns of Campylobacter coli 49941. Campylobacter spp. are small, asaccharolytic bacteria exhibiting unique nutritional and environmental requirements. Campylobacter spp. exist as commensal organisms in some animal species, yet are estimated to be the most common causative agents of foodborne illness in humans. C. jejuni is most often associated with poultry, while C. coli are more frequently associated with swine. Temperature has been suggested to trigger potential colonization or virulence factors in C. jejuni, and recent studies have demonstrated temperature-dependent genes are important to colonization. It is possible that temperature-dependent colonization factors are in part responsible for the species-specific colonization characteristics of C. coli also. We determined utilization of 190 different sole carbon substrates by C. coli ATCC 49941 at 37 and 42°C using phenotype microarray (PM) technology. Temperature did affect amino acid utilization. L-asparagine and L-serine allowed significantly (P = 0.004) more respiration by C. coli ATCC 49941 at the lower temperature of 37°C as compared to 42°C. Conversely, L-glutamine was utilized to a significantly greater extent (P = 0.015) at the higher temperature of 42°C. Other organic substrates exhibited temperature-dependent utilization including succinate, D,L-malate, and propionate which all supported active respiration by C. coli to a significantly greater extent at 42°C. Further investigation is needed to determine the basis for the temperature-dependent utilization of substrates by Campylobacter spp. and their possible role in species-specific colonization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981547"}
{"pmid": "20981548", "title": "Infection incidence and relative density of the bacteriophage WO-B in Aedes albopictus mosquitoes from fields in Thailand.", "content": "Infection incidence and relative density of the bacteriophage WO-B in Aedes albopictus mosquitoes from fields in Thailand. We have used real-time quantitative PCR to measure, for the first time, the relative phage WO-B orf7 density and infection incidence in Aedes albopictus mosquitoes from fields in Thailand. Our results showed that the infection incidence of phage WO-B in this mosquito, sampled from geographically different places in Thailand, was 97.9%. Average relative densities of the offspring were different when collected from diverse parts and reared under the same conditions in the laboratory. Our results also revealed that geographical differences within Thailand did not influence the maternal transmission rate of bacteriophage WO-B. In addition, the orf7 loci might not be strictly associated with Wolbachia, because less than 100% of them were maternally inherited. This discovery does not support the hypothesis that bacteriophage WO-B is involved in Aedes albopictus' cytoplasmic incompatibility. Whether this bacteriophage actually is involved in Wolbachia-induced cytoplasmic incompatibility in this mosquito thus needs further investigation, and additional densities of phage WO-B loci should be integrated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981548"}
{"pmid": "20981545", "title": "Phase II trial of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehydethiosemicarbazone plus gemcitabine in patients with advanced biliary tract cancer.", "content": "Phase II trial of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehydethiosemicarbazone plus gemcitabine in patients with advanced biliary tract cancer. 3-Aminopyridine-2-carboxaldehydethiosemicarbazone (3-AP) is a novel small molecule ribonucleotide reductase (RR) inhibitor which is more potent than hydroxyurea, the prototype of RR inhibitors. 3-AP enhances the cellular uptake and DNA incorporation of gemcitabine in tumor cell lines. We evaluated the combination of 3-AP plus gemcitabine in advanced biliary tract adenocarcinoma. Thirty-three patients with advanced adenocarcinoma of the gall bladder or biliary tract received gemcitabine (1,000 mg/m(2) on days 1, 8, and 15 every 28 days) 1 h after completing a 4-h infusion of 3-AP given at a dose of 105 mg/m(2) in patients with normal liver function (stratum A) or 80 mg/m(2) if abnormal liver function (stratum B). The trial was designed to determine whether the response rate was at least 30% in stratum A and 20% in stratum B. Objective response occurred in 3 of 23 patients (13%, 95% confidence intervals [CI] 3, 34%) with normal liver function, and in 0 of 10 patients with abnormal liver function. The most common grade 3-4 adverse events in all patients included neutropenia (42%), infection (33%), thrombocytopenia (27%), anemia (18%), and fatigue (15%). Fine needle aspiration of tumor samples obtained before and 24 h after 3-AP therapy showed increased R2 mRNA expression by in situ RT-PCR, suggesting RR inhibition. Despite evidence for RR inhibition in vivo, the 3-AP plus gemcitabine combination is not likely to be associated with a response rate exceeding 30% in patients with adenocarcinoma of the biliary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981545"}
{"pmid": "20981549", "title": "Vasotocin- and mesotocin-induced increases in short-circuit current across tree frog skin.", "content": "Vasotocin- and mesotocin-induced increases in short-circuit current across tree frog skin. In adult amphibian skin, Na(+) crosses from outside to inside. This Na(+) transport can be measured as the amiloride-blockable short-circuit current (SCC) across the skin. We investigated the effects of arginine vasotocin (AVT) and mesotocin (MT), and those of antagonists of the vasopressin and oxytocin receptors, on the SCC across Hyla japonica skin. (1) Both AVT (100 pmol/L or more) and MT (1 nmol/L or more) increased the SCC. (2) The AVT- and MT-induced increases in SCC recovered with time (downregulation). (3) These AVT/MT-induced effects were blocked by application of OPC-31260 (vasopressin V(2)-receptor antagonist). (4) The OPC-31260 concentration needed to block the AVT-induced response was lower upon post-application (after application of agonist) than upon pre-application (before application of agonist), suggesting the number of receptors may have decreased after AVT application. (5) Upon repeated application of AVT (100 pmol/L), the induced SCC increase did not differ significantly between the 1st and 2nd applications. (6) The time to reach the half-maximum value of the AVT-induced or MT-induced increase in SCC was not significantly different between washout and post-application of OPC-31260, suggesting that post-application of OPC-31260 cleared AVT and MT from their receptors. The effects of AVT, MT, and their antagonists in H. japonica, which is adapted to a terrestrial habitat, are compared with our previously published data on Rana catesbeiana (=Lithobates catesbeianus), which is adapted to a semiaquatic habitat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981549"}
{"pmid": "20981550", "title": "Intra- and extracellular osmotic regulation in the hololimnetic Caridea and Anomura: a phylogenetic perspective on the conquest of fresh water by the decapod Crustacea.", "content": "Intra- and extracellular osmotic regulation in the hololimnetic Caridea and Anomura: a phylogenetic perspective on the conquest of fresh water by the decapod Crustacea. We investigate extra- and intracellular osmoregulatory capability in two species of hololimnetic Caridea and Anomura: Macrobrachium brasiliense, a palaemonid shrimp, and Aegla franca, an aeglid anomuran, both restricted to continental waters. We also appraise the sharing of physiological characteristics by the hololimnetic Decapoda, and their origins and role in the conquest of fresh water. Both species survive salinity exposure well. While overall hyperosmoregulatory capability is weak in A. franca and moderate in M. brasiliense, both species strongly hyporegulate hemolymph [Cl(-)] but not osmolality. Muscle total free amino acids (FAA) increase slowly but markedly in response to the rapid rise in hemolymph osmolality consequent to hyperosmotic challenge: 3.5-fold in A. franca and 1.9-fold in M. brasiliense. Glycine, taurine, arginine, alanine and proline constitute ≈85% of muscle FAA pools in fresh water; taurine, arginine, alanine each contribute ≈22% in A. franca, while glycine predominates (70%) in M. brasiliense. These FAA also show the greatest increases on salinity challenge. Muscle FAA titers correlate strongly (R = 0.82) with hemolymph osmolalities across the main decapod sub/infraorders, revealing that marine species with high hemolymph osmolalities achieve isosmoticity of the intra- and extracellular fluids partly through elevated intracellular FAA concentrations; freshwater species show low hemolymph osmolalities and exhibit reduced intracellular FAA titers, consistent with isosmoticity at a far lower external osmolality. Given the decapod phylogeny adopted here and their multiple, independent invasions of fresh water, particularly by the Caridea and Anomura, our findings suggest that homoplastic strategies underlie osmotic and ionic homeostasis in the extant freshwater Decapoda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981550"}
{"pmid": "20981551", "title": "Feeding into old age: long-term effects of dietary fatty acid supplementation on tissue composition and life span in mice.", "content": "Feeding into old age: long-term effects of dietary fatty acid supplementation on tissue composition and life span in mice. Smaller mammals, such as mice, possess tissues containing more polyunsaturated fatty acids (PUFAs) than larger mammals, while at the same time live shorter lives. These relationships have been combined in the 'membrane pacemaker hypothesis of aging'. It suggests that membrane PUFA content might determine an animal's life span. PUFAs in general and certain long-chain PUFAs in particular, are highly prone to lipid peroxidation which brings about a high rate of reactive oxygen species (ROS) production. We hypothesized that dietary supplementation of either n-3 or n-6 PUFAs might affect (1) membrane phospholipid composition of heart and liver tissues and (2) life span of the animals due to the altered membrane composition, and subsequent effects on lipid peroxidation. Therefore, we kept female laboratory mice from the C57BL/6 strain on three diets (n-3 PUFA rich, n-6 PUFA rich, control) and assessed body weights, life span, heart, and liver phospholipid composition after the animals had died. We found that while membrane phospholipid composition clearly differed between feeding groups, life span was not directly affected. However, we were able to observe a positive correlation between monounsaturated fatty acids in cardiac muscle and life span.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981551"}
{"pmid": "20981552", "title": "Overwinter body temperature patterns in captive jerboas (Jaculus orientalis): influence of sex and group.", "content": "Overwinter body temperature patterns in captive jerboas (Jaculus orientalis): influence of sex and group. The jerboa (Jaculus orientalis) has been described in the past as a hibernator, but no reliable data exist on the daily and seasonal rhythmicity of body temperature (T (b)). In this study, T (b) patterns were determined in different groups of jerboas (isolated males and females, castrated males and grouped animals) maintained in captivity during autumn and winter, and submitted to natural variations of light and ambient temperature (T (a)). T (b) and T (a) variations were recorded with surgically implanted iButton temperature loggers at 30-min intervals for two consecutive years. About half (6/13) of isolated female jerboas hibernated with a T (b) < 33°C, with hibernation bouts interspersed with short periods of normothermy from November to February. Hibernation bout durations were longer (4-5 days) than those of normothermia phases (1-4 days). During hibernation, the minimum T (b) was low (T (b)min ~10.7°C). In contrast, one of the 12 isolated males showed short hibernation bouts of ca. 2 days late in the hibernation season, February-March. The males had T (b)min values of 15.1°C. In contrast to predictions, no castrated males hibernated. When jerboas were grouped, females and males exhibited concomitant torpor bouts. In males, the longest bouts were observed during the late hibernation season. These data suggest complex regulation of hibernation in jerboas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981552"}
{"pmid": "20981553", "title": "Diabetes mellitus abrogates erythropoietin-induced cardioprotection against ischemic-reperfusion injury by alteration of the RISK/GSK-3β signaling.", "content": "Diabetes mellitus abrogates erythropoietin-induced cardioprotection against ischemic-reperfusion injury by alteration of the RISK/GSK-3β signaling. Recent studies reported cardioprotective effects of erythropoietin (EPO) against ischemia-reperfusion (I/R) injury through activation of the reperfusion injury salvage kinase (RISK) pathway. As RISK has been reported to be impaired in diabetes and insulin resistance syndrome, we examined whether EPO-induced cardioprotection was maintained in rat models of type 1 diabetes and insulin resistance syndrome. Isolated hearts were obtained from three rat cohorts: healthy controls, streptozotocin (STZ)-induced diabetes, and high-fat diet (HFD)-induced insulin resistance syndrome. All hearts underwent 25 min ischemia and 30 min or 120 min reperfusion. They were assigned to receive either no intervention or a single dose of EPO at the onset of reperfusion. In hearts from healthy controls, EPO decreased infarct size (14.36 ± 0.60 and 36.22 ± 4.20% of left ventricle in EPO-treated and untreated hearts, respectively, p < 0.05) and increased phosphorylated forms of Akt, ERK1/2, and their downstream target GSK-3β. In hearts from STZ-induced diabetic rats, EPO did not decrease infarct size (32.05 ± 2.38 and 31.88 ± 1.87% in EPO-treated and untreated diabetic rat hearts, respectively, NS) nor did it increase phosphorylation of Akt, ERK1/2, and GSK-3β. In contrast, in hearts from HFD-induced insulin resistance rats, EPO decreased infarct size (18.66 ± 1.99 and 34.62 ± 3.41% in EPO-treated and untreated HFD rat hearts, respectively, p < 0.05) and increased phosphorylation of Akt, ERK1/2, and GSK-3β. Administration of GSK-3β inhibitor SB216763 was cardioprotective in healthy and diabetic hearts. STZ-induced diabetes abolished EPO-induced cardioprotection against I/R injury through a disruption of upstream signaling of GSK-3β. In conclusion, direct inhibition of GSK-3β may provide an alternative strategy to protect diabetic hearts against I/R injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981553"}
{"pmid": "20981555", "title": "Mannitol-1-phosphate dehydrogenase activity in Ectocarpus siliculosus, a key role for mannitol synthesis in brown algae.", "content": "Mannitol-1-phosphate dehydrogenase activity in Ectocarpus siliculosus, a key role for mannitol synthesis in brown algae. Mannitol represents a major end product of photosynthesis in brown algae (Phaeophyceae), and is, with the β-1,3-glucan laminarin, the main form of carbon storage for these organisms. Despite its importance, little is known about the genes and enzymes responsible for the metabolism of mannitol in these seaweeds. Taking benefit of the sequencing of the Ectocarpus siliculosus genome, we focussed our attention on the first step of the synthesis of mannitol (reduction of the photo-assimilate fructose-6-phosphate), catalysed by the mannitol-1-phosphate dehydrogenase (M1PDH). This activity was measured in algal extracts, and was shown to be regulated by NaCl concentration in the reaction medium. Genomic analysis revealed the presence of three putative M1PDH genes (named EsM1PHD1, EsM1PDH2 and EsM1PDH3). Sequence comparison with orthologs demonstrates the modular architecture of EsM1PHD1 and EsM1PDH2, with an additional N-terminal domain of unknown function. In addition, gene expression experiments carried out on samples harvested through the diurnal cycle, and after several short-term saline and oxidative stress treatments, showed that EsM1PDH1 is the most highly expressed of these genes, whatever the conditions tested. In order to assess the activity of the corresponding protein, this gene was expressed in Escherichia coli. Cell-free extracts prepared from bacteria containing EsM1PDH1 displayed higher M1PDH activity than bacteria transformed with an empty plasmid. Further characterisation of recombinant EsM1PDH1 activity revealed its very narrow substrate specificity, salt regulation, and sensitivity towards an inhibitor of SH-enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981555"}
{"pmid": "20981557", "title": "Solvent-free geranyl oleate production by enzymatic esterification.", "content": "Solvent-free geranyl oleate production by enzymatic esterification. This work reports the optimization of geranyl propionate production by esterification of geraniol and propionic acid in a solvent-free system using a commercial lipase as catalyst. For this purpose, a sequential strategy was performed applying two experimental designs. The operating conditions that optimized geranyl propionate production were determined to be 40 °C, geraniol to propionic acid molar ratio of 3:1, 150 rpm and 10 wt% of enzyme, with a resulting reaction conversion of about 93%. After determining the optimum reaction parameters, a kinetic study was carried out evaluating the influence of substrates molar ratio, enzyme concentration and temperature on reaction conversion. Results obtained in this step allow to conclude that an excess of alcohol (acid to alcohol molar ratio of 1:6), relatively low enzyme concentration (5 wt%), temperature of 40 °C and substrates molar ratio of 1:1 afforded nearly complete reaction conversion after 30 min of reaction. New experimental data on enzymatic esterification of geraniol and propionic acid for geranyl propionate production are reported in this work, showing a promising perspective of the technique to overcome the well-known drawbacks of the chemical-catalyzed route.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981557"}
{"pmid": "20981559", "title": "Determination of the complete nucleotide sequence of a lupine potyvirus isolate from the Czech Republic reveals that it belongs to a new member of the genus Potyvirus.", "content": "Determination of the complete nucleotide sequence of a lupine potyvirus isolate from the Czech Republic reveals that it belongs to a new member of the genus Potyvirus. The complete nucleotide sequence of the ssRNA genome of a lupine potyvirus (LP) isolate was determined. It comprised 10,113 nucleotides excluding the poly(A) tail. Phylogenetic analysis of CP protein sequences identified pepper veinal mottle virus, narcissus yellow stripe virus, and chili veinal mottle virus as the closest relatives, sharing coat protein amino acid sequence identities of only about 64% with the LP isolate. Thus, LP can be regarded as a member of a newly described potyvirus species, for which the name Lupine mosaic virus (LuMV) is proposed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981559"}
{"pmid": "20981554", "title": "Molecular mass spectrometry imaging in biomedical and life science research.", "content": "Molecular mass spectrometry imaging in biomedical and life science research. This review describes the current state of mass spectrometry imaging (MSI) in life sciences. A brief overview of mass spectrometry principles is presented followed by a thorough introduction to the MSI workflows, principles and areas of application. Three major desorption-ionization techniques used in MSI, namely, secondary ion mass spectrometry (SIMS), matrix-assisted laser desorption ionization (MALDI), and desorption electrospray ionization (DESI) are described, and biomedical and life science imaging applications of each ionization technique are reviewed. A separate section is devoted to data handling and current challenges and future perspectives are briefly discussed at the end.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981554"}
{"pmid": "20981556", "title": "ERCC2 Lys751Gln and Asp312Asn polymorphisms and gastric cancer risk: a meta-analysis.", "content": "ERCC2 Lys751Gln and Asp312Asn polymorphisms and gastric cancer risk: a meta-analysis. Studies investigating the association between excision repair cross-complimentary group 2 (ERCC2) polymorphisms and gastric cancer (GC) risk have reported conflicting results. We performed a meta-analysis of published epidemiological studies to derive a more precise estimation of the relationship. Published literature from PubMed, EMBASE, and China National Knowledge Infrastructure was retrieved. Ten studies with 2,141 GC cases and 5,343 controls were selected. No association between ERCC2 Lys751Gln polymorphism and GC susceptibility for all genetic models was found. When stratified by race, we found the Gln/Gln genotype carriers might be at high risk of GC among Asians, but not among Caucasians. Also, the pooled results showed there was a significant difference in genotype distribution between non-gastric cardia cancer cases and controls. For ERCC2 Asp312Asn polymorphism, significantly elevated GC risk was associated with Asn/Asn genotype (AA vs. GG + GA: OR = 1.36, 95%CI = 1.04-1.77, P = 0.02). We also found this genotype was associated with GC susceptibility among Asians and subjects without Helicobacter pylori infection. No publication bias was found in the present study. This meta-analysis concluded that both ERCC2 Lys751Gln and Asp312Asn polymorphisms might contribute to increased risk of GC among Asians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981556"}
{"pmid": "20981560", "title": "Molecular characterization and comparative analysis of pandemic H1N1/2009 strains with co-circulating seasonal H1N1/2009 strains from eastern India.", "content": "Molecular characterization and comparative analysis of pandemic H1N1/2009 strains with co-circulating seasonal H1N1/2009 strains from eastern India. During the peak outbreak (July-September 2009), a total 1886 patients were screened in eastern India, of which 139 (7.37%) and 52 (2.76%) were positive for pH1N1 and seasonal H1N1, respectively. Full-length HA1, NA, NS1 and PB1-F2 genes of representative strains were sequenced. Phylogenetic analysis of deduced amino acid sequences of pH1N1 strains revealed HA1 and NS1 to be of North American swine lineage, and the NA gene of Eurasian swine lineage. Consistent with previous reports, the PB1-F2 gene of pH1N1 strains was unique due to a mutation resulting in a truncated protein of 11 aa. The HA, NA and NS1 genes of H1N1/2009 strains clustered with H1N1 strains of 2000-2009, whereas a subset of strains contained a pH1N1-like truncated PB1-F2. The truncated PB1-F2 may confer the advantage of lower pathogenicity but higher replication and infectivity to the human H1N1 strains. This is the first report of seasonal H1N1/2009 strains with a pH1N1/2009-like gene segment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981560"}
{"pmid": "20981558", "title": "Expressed sequence-tag analysis of tobacco sperm cells reveals a unique transcriptional profile and selective persistence of paternal transcripts after fertilization.", "content": "Expressed sequence-tag analysis of tobacco sperm cells reveals a unique transcriptional profile and selective persistence of paternal transcripts after fertilization. Transcript analysis of male gametes of Nicotiana tabacum was conducted to gather gene expression data regarding the specialization of male germ cells and transmission of paternal transcripts during fertilization. We constructed a tobacco sperm cell cDNA library yielding 1,864 expressed sequence tags representing 1,050 clusters; 37.2% of these clusters have no homologs in GenBank, and 42% did not match any functionally classified protein. A comparative analysis of tobacco sperm transcripts with those of Arabidopsis and maize confirms that some genes are conserved in sperm specialization, while some are distinct to tobacco germline cells. Using reverse transcription-PCR (RT-PCR) of selected transcripts, we evaluated expression of sperm-obtained sequences in vegetative tissue, isolated egg cells, zygotes, and two-celled proembryos, identifying sperm cell-specific transcripts as potential markers for fertilization analysis. We further confirmed that two clusters of sperm transcripts were detected in zygotes about 10 h after fertilization, offering new examples of apparently paternally transmitted transcripts that may be involved in egg cell activation and/or early embryogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981558"}
{"pmid": "20981561", "title": "Brown tumor of the cervical spine: a case report and review of the literature.", "content": "Brown tumor of the cervical spine: a case report and review of the literature. Brown tumors (BT) are benign focal bone lesions that may appear in the context of primary and secondary hyperparathyroidism (HPT). Involvement of the spine is exceedingly rare. We present a case of brown tumor involving the cervical spine, the third reported in the literature. In the literature review (until August 2010), we found nine cases of spinal BT in primary HPT and 14 cases in secondary HPT. Fifteen patients (65%) had evidence of spinal cord compression. A 34-year-old woman on long-term hemodialysis, with secondary HPT, presented with a 9-month history of persistent neck pain. Radiographs of the cervical spine revealed an expansive osteolytic lesion in the posterior arch of the second cervical vertebra. MR imaging revealed an expansive mass on C2 affecting the vertebral body, odontoid process, right pedicle, laminas, and spinous process; there were no signs of spinal edema. A CT-guided needle biopsy of the lesion showed destruction of trabecular bone, infiltration of the fibroblastic cells, and abundant osteoclast-like multinucleated giant cells with hemorrhage and hemosiderin pigment, and the diagnosis of brown tumor was made. Cervical pain disappeared within a few days of parathyroidectomy, and rapid remineralization of C2 was evident within a few months. BT must always be considered in the context of hyperparathyroidism and osteolytic lesions. Vertebral BT can be particularly devastating due to medullar compression symptoms. Regression or complete disappearance of these lesions after parathyroidectomy is common, but prompt surgical decompression is necessary in case of medullar compression symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981561"}
{"pmid": "20981562", "title": "Comparison of two control measures of weatherstripping in reducing blowing dust during hospital renovations.", "content": "Comparison of two control measures of weatherstripping in reducing blowing dust during hospital renovations. Hospital renovation projects pose risks of invasive infection by fungi from dust that is blown about during the period in question. Control measures to reduce the amount of dust during hospital renovation are thus necessary. Currently, no study has compared different control measures for effectiveness through more than one period of renovation. In this study, we examined the capacities of two control measures of weatherstripping (0.15 mm poly film and adhesive tape) to reduce the amount of blowing dust during two different hospital renovations (in 2008 and 2009). The amount of dust in the air of the hospital before and during the renovation was measured about once a week in both 2008 and 2009, and the between-year and within-year differences were tested. Our study revealed that the weatherstripping used in 2009 (adhesive tape) was significantly more effective than the measures taken in 2008 (0.15 mm poly film) to reduce the amount of dust during the renovations (p < 0.001), while in both years the amount of dust became significantly higher during the renovations than before the renovations. Differences in the effectiveness of weatherstripping during renovations between floors of the hospital were not significant in both 2008 and 2009. The number of Aspergillus-positive samples did not significantly increase compared with the number observed before the start of the hospital renovations (2006-2007) in 2008 and 2009, respectively. The weatherstripping potentially reduced the associated risk of airborne fungal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981562"}
{"pmid": "20981564", "title": "Pollution of River Mahaweli and farmlands under irrigation by cadmium from agricultural inputs leading to a chronic renal failure epidemic among farmers in NCP, Sri Lanka.", "content": "Pollution of River Mahaweli and farmlands under irrigation by cadmium from agricultural inputs leading to a chronic renal failure epidemic among farmers in NCP, Sri Lanka. Chronic renal failure (CRF) associated with elevated dietary cadmium (Cd) among farming communities in the irrigated agricultural area under the River Mahaweli diversion scheme has reached a significantly higher level of 9,000 patients. Cadmium, derived from contaminated phosphate fertilizer, in irrigation water finds its way into reservoirs, and finally to food, causing chronic renal failure among consumers. Water samples of River Mahaweli and its tributaries in the upper catchment were analyzed to assess the total cadmium contamination of river water and the possible source of cadmium. Except a single tributary (Ulapane Stream, 3.9 μg Cd/l), all other tested tributaries carried more than 5 μg Cd/l, the maximum concentration level accepted to be safe in drinking water. Seven medium-sized streams carrying surface runoff from tea estates had 5.1-10 μg Cd/l. Twenty larger tributaries (Oya), where the catchment is under vegetable and home garden cultivation, carried 10.1-15 μg Cd/l. Nine other major tributaries had extremely high levels of Cd, reaching 20 μg Cd/l. Using geographic information system (GIS), the area in the catchment of each tributary was studied. The specific cropping system in each watershed was determined. The total cadmium loading from each crop area was estimated using the rates and types of phosphate fertilizer used by the respective farmers and the amount of cadmium contained in each type of fertilizer used. Eppawala rock phosphate (ERP), which is mostly used in tea estates, caused least pollution. The amount of cadmium in tributaries had a significant positive correlation with the cadmium loading of the cropping system. Dimbula Tea Estate Stream had the lowest Cd loading (495.9 g/ha/year), compared with vegetable-growing areas in Uma Oya catchment with 50,852.5 g Cd/ha/year. Kendall's τ rank correlation value of total Cd loading from the catchment by phosphate fertilizer used in all crops in the catchment to the Cd content in the tributaries was +0.48. This indicated a major contribution by the cropping system in the upper catchment area of River Mahaweli to the eventual Cd pollution of river water. Low soil pH (4.5-5.2), higher organic matter content (2-3%), and 18-20 cmol/kg cation exchange capacity (CEC) in upcountry soil have a cumulative effect in the easy release of Cd from soil with the heavy surface runoff in the upcountry wet zone. In view of the existing water conveyance system from upcountry to reservoirs in North Central Province (NCP) through diversion of River Mahaweli, in addition to their own nonpoint pollution by triple superphosphate fertilizer (TSP), this demands a change in overall upper catchment management to minimize Cd pollution through agriculture inputs to prevent CRF due to elevated dietary cadmium among NCP farmers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981564"}
{"pmid": "20981565", "title": "Spectrofluorimetric methods for the determination of gemifloxacin in tablets and spiked plasma samples.", "content": "Spectrofluorimetric methods for the determination of gemifloxacin in tablets and spiked plasma samples. Two new, sensitive and selective spectrofluorimetric methods have been developed for the determination of gemifloxacin (GFX) in tablets and spiked plasma samples. Gemifloxacin, as a primary amine compound, reacts with 7-chloro-4-nitrobenzofurazon (NBD-Cl) (for method A) and fluorescamine (for method B) which are a highly sensitive fluorogenic reagents used in many investigations. For method A, the reaction product was measured spectrofluorimetrically at 516 nm with excitation at 451 nm. The reaction proceeded quantitatively at pH 8.5, 80 °C in 7 min. For method B, the method was based on the reaction between GFX and fluorescamine in borate buffer solution of pH 8.5 to give highly fluorescent derivatives that were measured at 481 nm using an excitation wavelength of 351 nm. The fluorescence intensity was directly proportional to the concentration over the range 40-200 ng mL(-1) and 100-1,200 ng mL(-1) for method A and B, respectively. Successful applications of the developed methods, for the drug determination in pharmaceutical preparations and spiked plasma samples, were performed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981565"}
{"pmid": "20981566", "title": "Soil microbial characteristics at the monitoring plots on windthrow areas of the Tatra National Park (Slovakia): their assessment as environmental indicators.", "content": "Soil microbial characteristics at the monitoring plots on windthrow areas of the Tatra National Park (Slovakia): their assessment as environmental indicators. This study focused on the responses of soil microorganisms to different management regimes on disturbed windthrow areas. Microbial parameters potentially serving as indicators of environmental changes within a long-term monitoring of forest development after large-scale disturbance events were assessed. Basal and substrate-induced respiration, N mineralisation, catalase activity, microbial biomass as well as functional diversity based on Biolog assay were determined in soil samples from three disturbed plots and an undisturbed reference plot in the Tatra National Park (Slovakia) since 2006. A relative congruence of inter-annual trends of microbial activity indicators at all plots results from a common response of microbiota to changes of climate at the landscape level after forest stands were destroyed. While catalase activity and functional diversity proved to be useful indicators of temporal trends, microbial biomass seems to reflect different management regimes at the disturbed plots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981566"}
{"pmid": "20981567", "title": "Comparative cancer risk assessment of THMs in drinking water from well water sources and surface water sources.", "content": "Comparative cancer risk assessment of THMs in drinking water from well water sources and surface water sources. This research evaluates the lifetime cancer risks from trihalomethanes in Tehran's drinking water. The Trihalomethanes were measured in seven different water districts. Sixty-three samples were taken from tap water across the city for 7 months. The samples were analyzed for trihalomethanes using US EPA method 524.2. The average concentration of total trihalomethanes in different districts were between 0.81 and 9.0 μg/L, and the highest concentrations were detected in district 2 at 19.5 μg/L. Total lifetime cancer risks assessment from exposure to trihalomethanes in drinking water (ingestion, inhalation, and skin routes) were performed for people living in different districts in Tehran. The lifetime cancer risk was 7.19 × 10(-5) in district 2 (a more affluent neighborhood) where mostly surface water sources is used to supply drinking water and 9.38 × 10(-6) in district 7 (a less affluent neighborhood) which is mainly supplied with well water sources. Based on the population data, the total expected lifetime cancer cases from exposure to trihalomethanes are 104, 108, 81, 81, 41, 27, and three for districts 1 through 7, respectively. The average lifetime cancer risk was 4.33 × 10(-5) which means a total of 606 lifetime cancer cases for the entire province of Tehran. The highest risk from THMs seems to be from the inhalation route followed by ingestion and dermal contacts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981567"}
{"pmid": "20981563", "title": "Preservation of positional identity in fetus-derived neural stem (NS) cells from different mouse central nervous system compartments.", "content": "Preservation of positional identity in fetus-derived neural stem (NS) cells from different mouse central nervous system compartments. Neural stem (NS) cells are a self-renewing population of symmetrically dividing multipotent radial glia-like stem cells, characterized by homogeneous expansion in monolayer. Here we report that fetal NS cells isolated from different regions of the developing mouse nervous system behave in a similar manner with respect to self-renewal and neuropotency, but exhibit distinct positional identities. For example, NS cells from the neocortex maintain the expression of anterior transcription factors, including Otx2 and Foxg1, while Hoxb4 and Hoxb9 are uniquely found in spinal cord-derived NS cells. This molecular signature was stable for over 20 passages and was strictly linked to the developmental stage of the donor, because only NS cells derived from E14.5 cortex, and not those derived from E12.5 cortex, carried a consistent transcription factor profile. We also showed that traits of this positional code are maintained during neuronal differentiation, leading to the generation of electrophysiologically active neurons, even if they do not acquire a complete neurochemical identity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981563"}
{"pmid": "20981568", "title": "Use of feathers of feral pigeons (Columba livia) as a technique for metal quantification and environmental monitoring.", "content": "Use of feathers of feral pigeons (Columba livia) as a technique for metal quantification and environmental monitoring. This study quantifies metal concentrations in washed and unwashed feathers of feral pigeons (Columba livia). The material was collected in two different sites: Goiânia (capital of Goiás State), with high anthropic activities, and Jataí (a city in Goiás), with low anthropic activities. Results revealed that metals such as Pb, Cr, and Cd were deposited in the feathers originating from air and soil (exogenous process). Other metals such as Cu, Fe, Mn, and Zn, which are part of the tissue constitution of a living being, were absorbed through the pigeons' diet (endogenous process). There was a statistically significant difference between mean values of Cd, Pb, and Cr in the three collection sites. The order of metal concentrations were Civic Square > Zoo > Jataí, which shows highest levels of metal contamination in anthropic environments. Significant differences between Cd, Pb, and Cr in washed and unwashed feathers suggest that metal concentrations are directly related to exposure time due to exogenous sources. We concluded that it is possible to quantify and monitor metal levels in the environment by analyzing the feathers of urban feral pigeons. Furthermore, unwashed feathers were especially efficient to investigate endogenous and exogenous absorption of the metals in our study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981568"}
{"pmid": "20981569", "title": "Use of fish functional traits to associate in-stream suspended sediment transport metrics with biological impairment.", "content": "Use of fish functional traits to associate in-stream suspended sediment transport metrics with biological impairment. Loss of ecological integrity due to excessive suspended sediment in rivers and streams is a major cause of water quality impairment in the USA. Current assessment protocols for development of sediment total maximum daily loads (TMDLs) lack a means to link temporally variable sediment transport rates with specific losses of ecological functions as loads increase. In order to accomplish this linkage assessment, a functional traits-based approach was used to correlate site occurrences of 17 fish species traits in three main groups (preferred rearing habitat, trophic feeding guild, and spawning behavior) with suspended sediment transport metrics. The sediment transport metrics included concentrations, durations, and dosages for a range of exceedance frequencies; and mean annual suspended sediment yields (SSY). In addition, this study in the Northwestern Great Plains Ecoregion examined trait relationships with three environmental gradients: channel stability, drainage area, and elevation. Potential stressor responses due to elevated suspended sediment concentration (SSC) levels were correlated with occurrences of five traits: preferred pool habitat; feeding generalists, omnivores, piscivores, and nest-building spawners; and development of ecologically based TMDL targets were demonstrated for specific SSC exceedance frequencies. In addition, reduced site occurrences for preferred pool habitat and nest-building spawners traits were associated with unstable channels and higher SSY. At an ecoregion scale, a functional traits assessment approach provided a means to quantify relations between biological impairment and episodically elevated levels of suspended sediment, supporting efforts to develop ecologically based sediment TMDLs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981569"}
{"pmid": "20981570", "title": "Advancing effects analysis for integrated, large-scale wildfire risk assessment.", "content": "Advancing effects analysis for integrated, large-scale wildfire risk assessment. In this article, we describe the design and development of a quantitative, geospatial risk assessment tool intended to facilitate monitoring trends in wildfire risk over time and to provide information useful in prioritizing fuels treatments and mitigation measures. The research effort is designed to develop, from a strategic view, a first approximation of how both fire likelihood and intensity influence risk to social, economic, and ecological values at regional and national scales. Three main components are required to generate wildfire risk outputs: (1) burn probability maps generated from wildfire simulations, (2) spatially identified highly valued resources (HVRs), and (3) response functions that describe the effects of fire (beneficial or detrimental) on the HVR. Analyzing fire effects has to date presented a major challenge to integrated risk assessments, due to a limited understanding of the type and magnitude of changes wrought by wildfire to ecological and other nonmarket values. This work advances wildfire effects analysis, recognizing knowledge uncertainty and appropriately managing it through the use of an expert systems approach. Specifically, this work entailed consultation with 10 fire and fuels program management officials from federal agencies with fire management responsibilities in order to define quantitative resource response relationships as a function of fire intensity. Here, we demonstrate a proof-of-concept application of the wildland fire risk assessment tool, using the state of Oregon as a case study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981570"}
{"pmid": "20981571", "title": "Formulation and stabilisation of the biocontrol yeast Pichia anomala.", "content": "Formulation and stabilisation of the biocontrol yeast Pichia anomala. The yeast Pichia anomala has antifungal activities and its potential in biocontrol and biopreservation has previously been demonstrated. To practically use an organism in such applications on a larger scale the microbe has to be formulated and stabilised. In this review we give an overview of our experience of formulating and stabilising P. anomala strain J121 in a wider perspective. The stabilisation techniques we have evaluated were liquid formulations, fluidised bed drying, lyophilisation (freeze-drying) and vacuum drying. With all methods tested it was possible to obtain yeast cells with shelf lives of at least a few months and in all cases the biocontrol activity was retained. Fluidised bed drying was dependent on the addition of cottonseed flour as a carrier during the drying process. In liquid formulations a sugar, preferentially trehalose, was a required additive. These two kinds of microbial stabilisation are easily performed and relatively inexpensive but in order to keep the cells viable the biomaterial has to be stored at cool temperatures. However, there is room for optimization, such as improving the growth conditions, or include preconditioning steps to enable the cells to produce more compatible solutes necessary to survive formulation, desiccation and storage. In contrast, lyophilisation and vacuum drying require a lot of energy and are thus expensive. On the other hand, the dried cells were mostly intact after one year of storage at 30°C. Inevitably, the choice of formulation and stabilisation techniques will be dependent also on the intended use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981571"}
{"pmid": "20981573", "title": "Assessment of left ventricular function: visual or quantitative?", "content": "Assessment of left ventricular function: visual or quantitative?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981573"}
{"pmid": "20981575", "title": "A review of the pharmacological effects of Arctium lappa (burdock).", "content": "A review of the pharmacological effects of Arctium lappa (burdock). Arctium lappa, commonly known as burdock, is being promoted/recommended as a healthy and nutritive food in Chinese societies. Burdock has been used therapeutically in Europe, North America and Asia for hundreds of years. The roots, seeds and leaves of burdock have been investigated in view of its popular uses in traditional Chinese medicine (TCM). In this review, the reported therapeutic effects of the active compounds present in the different botanical parts of burdock are summarized. In the root, the active ingredients have been found to \"detoxify\" blood in terms of TCM and promote blood circulation to the skin surface, improving the skin quality/texture and curing skin diseases like eczema. Antioxidants and antidiabetic compounds have also been found in the root. In the seeds, some active compounds possess anti-inflammatory effects and potent inhibitory effects on the growth of tumors such as pancreatic carcinoma. In the leaf extract, the active compounds isolated can inhibit the growth of micro-organisms in the oral cavity. The medicinal uses of burdock in treating chronic diseases such as cancers, diabetes and AIDS have been reported. However, it is also essential to be aware of the side effects of burdock including contact dermatitis and other allergic/inflammatory responses that might be evoked by burdock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981575"}
{"pmid": "20981576", "title": "Incorporation of in silico biodegradability screening in early drug development--a feasible approach?", "content": "Incorporation of in silico biodegradability screening in early drug development--a feasible approach? The concentration of a pharmaceutical found in the environment is determined by the amount used by the patient, the excretion and metabolism pattern, and eventually by its persistence. Biological degradation or persistence of a pharmaceutical is experimentally tested rather late in the development of a pharmaceutical, often shortly before submission of the dossier to regulatory authorities. To investigate whether the aspect of persistence of a compound could be assessed early during drug development, we investigated whether biodegradation of pharmaceuticals could be predicted with the help of in silico tools. To assess the value of in silico prediction, we collected results for the OECD 301 degradation test (\"ready biodegradability\") of 42 drugs or drug synthesis intermediates and compared them to the prediction of the in silico tool BIOWIN. Of these compounds, 38 were predictable with BIOWIN, which is a module of the Estimation Programs Interface (EPI) Suite™ provided by the US EPA. The program failed to predict the two drugs which proved to be readily biodegradable in the degradation tests. On the other hand, BIOWIN predicted two compounds to be readily biodegradable which, however, proved to be persistent in the test setting. The comparison of experimental data with the predicted one resulted in a specificity of 94% and a sensitivity of 0%. The results of this study do not indicate that application of the biodegradation prediction tool BIOWIN is a feasible approach to assess the ready biodegradability during early drug development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981576"}
{"pmid": "20981572", "title": "Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice.", "content": "Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice. Endogenous hydrogen sulfide (H(2)S) is increasingly being recognized as an important gaseous physiological mediator. Accumulating evidence shows the functions of H(2)S in various models of disease, but rarely in colitis. In this study, we investigated the role of endogenous H(2)S in a dextran sodium sulfate (DSS)-induced colitis model. Acute colitis was induced using 8% DSS in male BALB/c mice. The mRNA expression of cystathionine γ-lyase (CSE), the primary synthetase of H(2)S in the gastrointestinal tract, and cystathionine-β-synthetase (CBS) was measured by real-time RT-PCR. The amount of H(2)S in the colonic mucosa was measured by gas chromatography. Colitis severity was evaluated clinically, histologically, and biochemically under the condition of co-treatment with DL-propargylglycine (PAG), an irreversible CSE inhibitor, and sodium sulfide (Na(2)S), an H(2)S donor. The mRNA expression levels of CSE and CBS, and the H(2)S content in the colonic mucosa were increased with time after DSS administration. The disease activity index, which was determined by weight loss, stool consistency, and intestinal bleeding, increased after DSS administration. PAG significantly enhanced the increase in the disease activity index scores. PAG also significantly increased tissue-associated myeloperoxidase activity and thiobarbituric acid-reactive substances in the inflamed mucosa. Moreover, Na(2)S counteracted these effects of PAG. Taken together, the results indicated that the inhibition of endogenous H(2)S generation caused the deterioration of DSS-induced colitis. We conclude that physiological H(2)S might act as an anti-inflammatory molecule in colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981572"}
{"pmid": "20981574", "title": "Anti-inflammatory and immunomodulatory effects of RDV-8 [C18H22N2O2S (ethyl 1-butyl-6-methyl-2-phenyl-4-thioxo-1,4-dihydropyrimidine-5-carboxylate)] in a rat model of induced pleurisy and in vitro lymphoproliferation.", "content": "Anti-inflammatory and immunomodulatory effects of RDV-8 [C18H22N2O2S (ethyl 1-butyl-6-methyl-2-phenyl-4-thioxo-1,4-dihydropyrimidine-5-carboxylate)] in a rat model of induced pleurisy and in vitro lymphoproliferation. RDV-8 [C(18)H(22)N(2)O(2)S (ethyl 1-butyl-6-methyl-2-phenyl-4-thioxo-1,4-dihydropyrimidine-5-carboxylate)] is derived from the 4-thioxopyrimidine, and presents important clinical effects. The present study explored the RDV-8 effects in the proliferation of human peripheral blood mononuclear cells (PBMCs), as well as in a pleurisy-induced rat model. PBMCs were directly plated in four different RDV-8 concentrations (0.0125, 0.025, 0.05 and 0.1 mg/mL). RDV-8 decreased cell proliferation and monocyte chemotactic protein 1 synthesis. The interleukin 1 levels and the cytotoxic effect were not significantly affected by RDV-8 treatment. In the carrageenan-induced pleurisy model, the RDV-8 (3 mg/kg) treatment induced a significant reduction in the exudate volume, in the polymorphonuclear leukocyte migration and in the pleural exudate NO levels. The results indicate that RDV-8 may have an immunomodulatory effect, as well as anti-inflammatory actions suggesting that it could represent a new strategy in the inflammatory response modulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981574"}
{"pmid": "20981577", "title": "Is looking older than one's actual age a sign of poor health?", "content": "Is looking older than one's actual age a sign of poor health? Physicians often begin the physical examination with an assessment of whether a patient looks older than his or her actual age. This practice suggests an implicit assumption that patients who appear older than their actual age are more likely to be in poor health. To determine the sensitivity and specificity of apparent age for the detection of poor health status. Cross-sectional. A total of 126 outpatients (ages 30-70) from four primary care clinics and one general internal medicine clinic at an academic medical institution. With the patient's actual age provided, physicians (n = 58 internal medicine residents and general internal medicine faculty) viewed patient photographs and assessed how old each patient looked. For each physician, we examined the sensitivity and specificity of the difference between how old the patient looked and the patient's actual age for the detection of poor health, defined using SF-12 physical health and mental health scores. Using the threshold of looking ≥ 5 years older than actual age and with poor health defined as an SF-12 score ≥ 2.0 SD below age group norms, median sensitivity was 29% (IQR, 19% to 35%), median specificity 82% (IQR, 77% to 88%), median positive likelihood ratio 1.7 (IQR, 1.3 to 2.2), and median negative likelihood ratio 0.9 (IQR, 0.8 to 0.9). Using the threshold of looking ≥ 10 years older than actual age, median sensitivity was 5% (IQR, 2% to 9%) and median specificity was 99% (IQR, 96% to 100%). The diagnostic value of apparent age depends on how many years older than his or her actual age a patient looks. A physician's assessment that a patient looks ≥ 10 years older than his or her actual age has very high specificity for the detection of poor health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981577"}
{"pmid": "20981578", "title": "Rosuvastatin and thapsigargin modulate γ-secretase gene expression and APP processing in a human neuroglioma model.", "content": "Rosuvastatin and thapsigargin modulate γ-secretase gene expression and APP processing in a human neuroglioma model. Alzheimer's disease (AD) is a progressive neurodegenerative disorder leading to slow neuronal loss in several brain regions. It is characterised by the presence of cerebral senile plaques comprised of aggregated amyloid-β peptides. Transcriptional regulation of the γ-secretase complex, which cleaves the β-amyloid precursor protein to produce Aβ-peptides, could modulate the pathological phenotype of AD patients. This study investigates whether rosuvastatin, an HMG-CoA reductase inhibitor, modulates the expression of genes involved in the function of the γ-secretase complex, in a human cellular model for Aβ peptide accumulation. In particular, we analysed the effect of the statin combined with apoptotic induction. Experimental apoptosis was induced by thapsigargin treatment, a drug that depletes intracellular calcium stores via inhibition of the calcium ATPase pump. Notably, systemic calcium dysregulation accompanies almost all of the brain pathology processes observed in AD. We found differential transcriptional regulation of some γ-secretase cofactors relative to rosuvastatin treatment, in cells expressing Swedish mutant APP. Interestingly, this statin down-regulated the transcription of some enzyme cofactors, similar to treatment with thapsigargin. However, rosuvastatin neither affected the basal Aβ levels nor counteracted APP processing or Aβ over-production triggered by the thapsigargin. Our results provide evidence that rosuvastatin alters gene expression of the γ-secretase complex without affecting enzyme activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981578"}
{"pmid": "20981586", "title": "Application of modeling to scale-up dissolution in pharmaceutical manufacturing.", "content": "Application of modeling to scale-up dissolution in pharmaceutical manufacturing. Liquid mixing scale-up in pharmaceutical industry has often been based on empirical approach in spite of tremendous understanding of liquid mixing scale-up in engineering fields. In this work, we attempt to provide a model-based approach to scale-up dissolution process from a 2 l lab-scale vessel to a 4,000 l scale vessel used in manufacturing. Propylparaben was used as a model compound to verify the model predictions for operating conditions at commercial scale that would result in similar dissolution profile as observed in lab scale. Geometric similarity was maintained between both of the scales to ensure similar mixing characteristics. We utilized computational fluid dynamics (CFD) to ensure that the operating conditions at laboratory and commercial scale will result in similar power per unit volume (P/V). Utilizing this simple scale-up criterion of similar P/V across different scales, results obtained indicate fairly good reproducibility of the dissolution profiles between the two scales. Utilization of concepts of design of experiments enabled summarizing scale-up results in statistically meaningful parameters, for example -90% dissolution in lab scale at a given time under certain operating conditions will result in 75-88% at commercial scale with 95% confidence interval when P/V is maintained constant across the two scales. In this work, we have successfully demonstrated that scale-up of solid dissolution can be done using a systematic process of lab-scale experiments followed by simple CFD modeling to predict commercial-scale experimental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981586"}
{"pmid": "20981579", "title": "Potential protective role of IL15Rα during inflammation.", "content": "Potential protective role of IL15Rα during inflammation. We have shown that TNFα specifically activates the interleukin-15 (IL15) system in cerebral endothelial cells composing the blood-brain barrier. To determine the functions of cerebral IL15 signaling in inflammation, we first treated mice with lipopolysaccharide (LPS) and determined the expression of the three receptor subtypes of IL15. Robust time-dependent upregulation occurred in all subunits. We then tested whether IL15Rα knockout (KO) affected the maintenance of body temperature and activity level after a single dose of LPS. Circadian telemetry data were analyzed by the cosinor method. Both wild-type and KO mice had clear 24-h rhythms of basal temperature and activity. KO mice had a significantly higher midline estimating statistic of rhythm (MESOR; approximating 24 h mean) of temperature and delayed 24-h acrophase (peak) of activity than the wild-type mice. LPS disrupted the circadian rhythm of activity more severely in the KO group. Besides a decrease in MESOR and 24-h amplitude of activity after LPS, the KO mice showed a significant reduction of MESOR, amplitude, and changed acrophase for temperature on the second of 2 days. The disrupted circadian rhythm of temperature and activity in the KO mice after LPS suggests that upregulated IL15 receptors may serve a beneficial role to counteract the consequences of neuroinflammation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981579"}
{"pmid": "20981585", "title": "Post-traumatic stress disorder in medical settings: focus on the critically ill.", "content": "Post-traumatic stress disorder in medical settings: focus on the critically ill. The relevance of the post-traumatic stress disorder (PTSD) concept to medically ill patients is becoming increasingly clear. Some medical conditions (e.g., rheumatologic diseases) are likely related to PTSD indirectly. Others, such as myocardial infarction and critical illness/intensive care unit (ICU) treatment, are likely traumatic stressors. Importantly, PTSD seems to be a potent risk factor for fatal and nonfatal cardiac events. Risk factors for medical illness-related PTSD appear similar to risk factors for PTSD in general. PTSD is particularly common among survivors of critical illness and ICU treatment. Further research is needed to determine how specific ICU interventions (e.g., administration of benzodiazepines, corticosteroids, and catecholamines) affect PTSD risk. In the meantime, given the negative impact of PTSD on patients' quality of life, it is important for psychiatrists and other clinicians to be aware of the syndrome in survivors of critical illness so as to ensure that such patients receive the care that they deserve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981585"}
{"pmid": "20981601", "title": "Evaluation of the oral ¹³C-bicarbonate tracer technique for the estimation of CO₂ production and energy expenditure in dogs during rest and physical activity.", "content": "Evaluation of the oral ¹³C-bicarbonate tracer technique for the estimation of CO₂ production and energy expenditure in dogs during rest and physical activity. For feeding of working dogs during their daily life, illness, routine jobs or sporting activities, an accurate determination of their nutritional requirements is essential to ensure their optimal health and performance. To predict the appropriate guidelines about how to feed dogs, it appears essential to determine the energy expenditure (EE) in a reliable and feasible way. In the present experiment, the non-invasive oral ¹³C-bicarbonate tracer technique (o¹³CT), i.e. collection of breath samples after oral administration of NaH¹³CO₃, was used for the estimation of CO₂ production and EE in dogs. Measurements were conducted during two days of rest, and during three days with 3 h of exercise per day. Average EE was 483 and 876 kJ kg⁻⁰·⁷⁵ d⁻¹ during rest and exercise, respectively. The o¹³CT seems appropriate to use as a minimal restrictive and non-invasive method to obtain reliable estimates of EE in dogs at different activity levels under near natural conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981601"}
{"pmid": "20981600", "title": "Spoilt for choice? Cross-sectional study of care-seeking for health problems during pregnancy in Mumbai slums.", "content": "Spoilt for choice? Cross-sectional study of care-seeking for health problems during pregnancy in Mumbai slums. This study considers care-seeking patterns for maternal morbidity in Mumbai's slums. Our objectives were to document women's self-reported symptoms and care-seeking, and to quantify their choice of health provider, care-seeking delays and referrals between providers. The hypothesis that care-seeking sites for maternal morbidity mirror those used for antenatal care was also tested. We analysed data for 10,754 births in 48 slum areas and interviewed mothers about their illnesses and care-seeking during pregnancy. Institutional care-seeking was high across the board (>80%), and higher for 'trigger' symptoms suggestive of complications (>88%). Private-sector care was preferred, and increased with socio-economic status, although public providers also played an important role. Most women sought treatment at the same site they received their antenatal care, most were treated within 2 days, and less than 2% were referred to other providers. Our findings suggest that poor women in Mumbai recognise symptoms of obstetric complications and the need for health care. However, that more than 80% also sought care for minor conditions implies that the tendency to seek institutional care for serious conditions reflects a broader picture of care-seeking for all illnesses. The role of private health-care providers needs greater recognition, and further research is required on provider motivations and behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981600"}
{"pmid": "20981602", "title": "Dynamic modelling and simulation of ¹⁵N separation by chemical exchange in NO, NO₂-HNO₃ system.", "content": "Dynamic modelling and simulation of ¹⁵N separation by chemical exchange in NO, NO₂-HNO₃ system. The dynamic behaviour of a ¹⁵N separation process by chemical exchange in a NO, NO₂-HNO₃ system has been analysed based on an accurate mathematical model. A nonlinear system of first-order partial differential equations was determined by considering the multiple exchange reactions between the components of the gaseous mixture and the liquid phase constituents. The mathematical model of the process describes the space-time variation of the ¹⁵N mole fraction in gas and liquid phases and provides a better understanding of operating limits and decision support in process design and optimisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981602"}
{"pmid": "20981603", "title": "Biodegradation kinetics of 2,6-dihydroxybenzoic acid and peptone mixture by acclimated microbial culture at low sludge age.", "content": "Biodegradation kinetics of 2,6-dihydroxybenzoic acid and peptone mixture by acclimated microbial culture at low sludge age. This study evaluated the kinetics of 2,6-dihydroxybenozic acid and peptone biodegradation at low sludge age by acclimated culture under aerobic conditions. A laboratory-scale sequencing batch reactor was set and fed with peptone mixture. The system was operated at steady-state at a sludge age of 2 days. In order to assess biodegradation kinetics of 2,6-dihydroxybenozic acid and its impact on peptone utilization, a mixture of 2,6-dihydroxybenzoic acid and peptone was fed to mixed culture. After a period of four days, the system became acclimated to simultaneously remove both 2,6-dihydroxybenzoic acid and peptone mixture. A mechanistic model was developed involving model components and kinetic parameters for both substrates. This model was calibrated with related experimental data such as oxygen uptake rate and COD. Biodegradation characteristics and kinetics of peptone and 2,6-dihydroxybenzoic acid was estimated. The evaluation of calibrated model indicated that a group of microorganisms adjusted their enzymatic tools for the utilization of 2,6-dihydroxybenzoic acid resulting in dual microbial community development at low sludge age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981603"}
{"pmid": "20981605", "title": "Natural radionuclide emission from coal-fired power plants in the southwestern of Turkey and the population exposure to external radiation in their vicinity.", "content": "Natural radionuclide emission from coal-fired power plants in the southwestern of Turkey and the population exposure to external radiation in their vicinity. To evaluate the effect of radionuclide emission on the environment from Yatagan, Yenikoy and Kemerkoy coal-fired power plants which are located in southwestern Anatolia of Turkey, the concentrations of natural radionuclides such as (226)Ra, (232)Th and (40)K in coal, bottom ash and fly ash samples, have been measured, as well as the concentration of the same radionuclides in surface soils. The dose rate arises from the total radioactivity content of soil that the people living by the power plants are exposed to be assessed additionally. The average activity concentrations of (226)Ra for Yatagan CPP is 80 ± 22 Bq kg(-1) ranging from 56 to 131 Bq kg(-1), for Yenikoy CPP is 138 ± 20 Bq kg(-1) ranging from 115 to 189 Bq kg(-1), for Kemerkoy CPP is 238 ± 80 Bq kg(-1) ranging from 134 to 356 Bq kg(-1) in coal; average activity concentrations of (226)Ra in fly ash and in bottom ash for above-mentioned power plants are 334 ± 60 Bq kg(-1) ranging from 291 to 481 Bq kg(-1), 461 ± 33 Bq kg(-1) ranging from 398 to 511 Bq kg(-1), 815 ± 254 Bq kg(-1) ranging from 316 to 1260 Bq kg(-1), 276 ± 51 Bq kg(-1) ranging from 222 to 349 Bq kg(-1), 285 ± 69 Bq kg(-1) ranging from 213 to 409 Bq kg(-1), 743 ± 234 Bq kg(-1) ranging from 366 to 1098 Bq kg(-1), respectively. The radionuclides activity concentrations of surface soil in the vicinity of coal-fired power plants are 32 ± 9 Bq kg(-1) (18-53 Bq kg(-1)) for (226)Ra, 37 ± 16 Bq kg(-1) (17-89 Bq kg(-1)) for (232)Th, 455 ± 165 Bq kg(-1) (203-794 Bq kg(-1)) for (40)K relevant to Yatagan CPP; 42 ± 30 Bq kg(-1) (9-168 Bq kg(-1)) for (226)Ra, 32 ± 14 Bq kg(-1) (6-74 Bq kg(-1)) for (232)Th, 365 ± 151 Bq kg(-1) (117-937 Bq kg(-1)) for (40)K relevant to Yenikoy and Kemerkoy CPP. As a result, average dose rates in the vicinity of coal-fired power plants have been calculated to be 56 ± 16 nGy h(-1) ranging from 30 to 100 nGy h(-1) for Yatagan CPP, 54 ± 22 nGy h(-1) ranging from 15 to 126 nGy h(-1) for Yenikoy and Kemerkoy CPP. To sum up, the natural radionuclide activity concentrations of burnt coal and ashes thrown out from these three power plants are quite high relative to the world average UNSCEAR[1] data. In addition, the average (226)Ra, (232)Th and (40)K activity concentration values of surface soil samples and the calculated gamma dose rates in the vicinity of power plants were located within the worldwide intervals reported by UNSCEAR,[30] with some local differences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981605"}
{"pmid": "20981606", "title": "Agrochemical spray drift; assessment and mitigation--a review.", "content": "Agrochemical spray drift; assessment and mitigation--a review. During application of agrochemicals spray droplets can drift beyond the intended target to non-target receptors, including water, plants and animals. Factors affecting this spray drift include mode of application, droplet size, which can be modified by the nozzle types, formulation adjuvants, wind direction, wind speed, air stability, relative humidity, temperature and height of released spray relative to the crop canopy. The rate of fall of spray droplets depends upon the size of the droplets but is modified by entrainment in a mobile air mass and is also influenced by the rate of evaporation of the liquid constituting the aerosol. The longer the aerosol remains in the air before falling to the ground (or alternatively striking an object above ground) the greater the opportunity for it to be carried away from its intended target. In general, all size classes of droplets are capable of movement off target, but the smallest are likely to move the farthest before depositing on the ground or a non-target receptor. It is not possible to avoid spray drift completely but it can be minimized by using best-management practices. These include using appropriate nozzle types, shields, spray pressure, volumes per area sprayed, tractor speed and only spraying when climatic conditions are suitable. Field layout can also influence spray drift, whilst crop-free and spray-free buffer zones and windbreak crops can also have a mitigating effect. Various models are available to estimate the environmental exposure from spray drift at the time of application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981606"}
{"pmid": "20981604", "title": "Spatiotemporal trends of heavy metal concentrations in fish of the River Morava (Danube basin).", "content": "Spatiotemporal trends of heavy metal concentrations in fish of the River Morava (Danube basin). The aim of this study was to assess mercury (Hg), cadmium (Cd) and lead (Pb) contamination in muscle tissue of fishes over the longitudinal profile of the River Morava (Czech Republic, Danube basin) and to detect any temporal trends over the past 18 years. Fish samples were collected in 1992, 1998, 2000, 2003 and 2009 at 6 study sites situated just downstream of important pollution sources. Chub (Leuciscus cephalus L.) were selected as indicator species at 5 sites, and brown trout (Salmo trutta m. fario L.) at the uppermost site where chub do not occur. In total, muscle tissue of 175 specimens of chub and 19 specimens of brown trout were analysed. Concentrations of heavy metals ranged as follows: mercury 0.015-0.369 mg/kg; cadmium 0.001-0.254 mg/kg and lead 0.006-1.505 mg/kg. Mercury levels did not exceed the maximum allowed concentration in the Czech Republic (0.5 mg/kg). Content of cadmium and lead in fish muscle exceeded the maximum allowed levels (0.05 and 0.3 mg/kg respectively) in 11 and 4 samples, respectively. On average, the order of metal concentration in fish muscle was: Hg>Pb>Cd. No significant differences were found between sites along the longitudinal profile of the river. Significant differences were found, however, for the interannual comparison of cadmium and lead (but not mercury) at different sites (P < 0.05). A catastrophic flood in 1997 resulted in an increase in metal concentrations, especially cadmium and lead, in the following 1998 season. Our results indicate that the Morava river basin does not represent a threatening source of mercury, cadmium or lead for the River Danube downstream.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981604"}
{"pmid": "20981607", "title": "Occupational exposure to hazardous airborne pollutants: effects of air mixing and source location.", "content": "Occupational exposure to hazardous airborne pollutants: effects of air mixing and source location. The presence of airborne pollutants in indoor environments has been associated with occupants' discomfort and/or adverse health effects. This study investigates occupational exposure in relation to indoor air mixing and source location relative to a human body. Experimental and computational methods were used to provide information about the pollutant distribution in the vicinity of the human body for different levels of room air mixing. Study results show that the often used assumption of uniform pollutant distribution in an occupied space is not always appropriate for estimation of inhalation exposure. Results also indicate that an occupant may experience very high acute exposure to airborne pollutants when little air mixing exists in a space and the pollutant source is in the vicinity of the occupant. The buoyancy-driven flow induced by the convective heat transfer from an occupant's body can transport pollutants in the occupant's vicinity to the breathing zone. Specific study results reveal that a source located in the occupant's front chest region makes a relatively large contribution to the breathing zone concentration compared with the other sources in the vicinity of the human body. With the source position in this region, exposure can be nine times greater than that calculated with the uniform mixing assumption. The buoyancy-driven convective plume around a body seems to have a significant influence on pollutant transport and human exposure, especially in the absence of room air mixing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981607"}
{"pmid": "20981608", "title": "Sequences of upper and lower extremity motions in javelin throwing.", "content": "Sequences of upper and lower extremity motions in javelin throwing. Javelin throwing is technically demanding. Sequences of upper and lower extremity motions are important for javelin throwing performance. The purpose of this study was to determine the general sequences of upper and lower extremity motions of elite male and female javelin throwers. Three-dimensional kinematic data were collected for 32 female and 30 male elite javelin throwers during competitions. Shoulder, elbow, wrist, hip, knee, ankle, lower trunk, and upper trunk joint and segment angles were reduced for the best trial of each participant. Beginning times of 6 upper extremity and 10 lower extremity joint and segment angular motions were identified. Sequences of the upper and lower extremity motions were determined through statistical analyses. Upper and lower extremity motions of the male and female elite javelin throwers followed specific sequences (P ≤ 0.050). Upper extremity motions of the male and female elite javelin throwers did not follow a proximal-to-distal sequence as suggested in the literature. Male and female elite javelin throwers apparently employed different sequences for upper and lower extremity motions (P < 0.001). Further studies are needed to determine the effects of sequences of upper and lower extremity motions on javelin throwing performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981608"}
{"pmid": "20981609", "title": "Extra-curricular participation in sports and socio-demographic factors in Spanish adolescents: the AVENA study.", "content": "Extra-curricular participation in sports and socio-demographic factors in Spanish adolescents: the AVENA study. The aims of this study were to identify differences between the sexes in extra-curricular participation in sports and to determine its association with body fat and socio-demographic factors in Spanish adolescents. A total of 2165 adolescents (1124 males and 1041 females) aged 13.0-18.5 years from the AVENA Study participated. Participants filled in an ad hoc questionnaire for extra-curricular participation in sports, which was the dependent variable. Independent variables were: age, percent body fat, and father's and mother's educational level and occupation. Chi-square tests and logistic regression were applied. Bivariate analysis showed for male adolescents that age and father's occupation were related to extra-curricular participation in sports. In addition, body fat and mother's education and occupation (all P < 0.05) were related to extra-curricular participation of in sports for female adolescents. Logistic regression analysis showed that the likelihood of involvement in extra-curricular participation in sports was 5.3-fold (3.86-7.38) higher for males than females. Age and father's education in both males and females were independently associated with extra-curricular participation in sports. In summary, Spanish male adolescents were shown to engage in more extra-curricular sports than females. In addition, age and father's education (in both sexes) were associated with the participation of their offspring in extra-curricular sports during adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981609"}
{"pmid": "20981610", "title": "Digit ratio (2D:4D) and performance in elite rugby players.", "content": "Digit ratio (2D:4D) and performance in elite rugby players. The relative length of the second and fourth digits (2D:4D) is a putative marker for prenatal testosterone. Low 2D:4D has been reported to correlate with high performance in sport in general. Here, for the first time, we examine the relationship between 2D:4D and performance in elite rugby players. The 44 players (28 forwards, 16 backs) were drawn from the Ospreys Rugby Union Club and 44 age-matched controls. The measures of performance comprised age-adjusted number of international performances (caps) for Wales, a comparison of coaches' first-choice League team with others, and the number of tries scored by backs in club matches. Compared with controls, players were larger and had lower 2D:4D for the right and left hand. With regard to number of caps, players with low 2D:4D in their right hand and low right 2D:4D compared with their left (right - left 2D:4D difference) had high numbers of caps. First-choice players did not differ significantly from second-choice players in their 2D:4D but they did have a lower right - left 2D:4D difference than second-choice players. Low right 2D:4D and low right - left 2D:4D difference were significantly linked with large numbers of tries. We conclude that low right 2D:4D and low right - left 2D:4D difference are predictors of high rugby performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981610"}
{"pmid": "20981612", "title": "Inhibition of histamine mediated responses by Mirabilis jalapa: confirming traditional claims made about antiallergic and antiasthmatic activity.", "content": "Inhibition of histamine mediated responses by Mirabilis jalapa: confirming traditional claims made about antiallergic and antiasthmatic activity. The roots of Mirabilis jalapa are used traditionally in allergic skin disorders and asthma. The effect of an ethanol:acetone (1:1) extract of the roots of M. jalapa was studied for antihistaminic activity using a guinea pig tracheal chain preparation and clonidine-induced mast cell granulation in mice. Its antiallergic activity was evaluated using milk-induced eosinophilia and albumin-induced paw oedema in mice. The extract (0.5 mL of 100 mg mL(-1)) inhibited histamine-induced guinea pig tracheal chain contractions non-competitively. The extract (100 or 200 mg kg(-1) i.p.) inhibited milk-induced eosinophilia, albumin-induced paw oedema and protected mast cells against clonidine-induced granulation. The study justified the folkloric use of M. jalapa in the treatment of allergic diseases and asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981612"}
{"pmid": "20981611", "title": "Gender differences in autobiographical memory for everyday events: retrieval elicited by SenseCam images versus verbal cues.", "content": "Gender differences in autobiographical memory for everyday events: retrieval elicited by SenseCam images versus verbal cues. Gender differences are frequently observed in autobiographical memory (AM). However, few studies have investigated the neural basis of potential gender differences in AM. In the present functional MRI (fMRI) study we investigated gender differences in AMs elicited using dynamic visual images vs verbal cues. We used a novel technology called a SenseCam, a wearable device that automatically takes thousands of photographs. SenseCam differs considerably from other prospective methods of generating retrieval cues because it does not disrupt the ongoing experience. This allowed us to control for potential gender differences in emotional processing and elaborative rehearsal, while manipulating how the AMs were elicited. We predicted that males would retrieve more richly experienced AMs elicited by the SenseCam images vs the verbal cues, whereas females would show equal sensitivity to both cues. The behavioural results indicated that there were no gender differences in subjective ratings of reliving, importance, vividness, emotion, and uniqueness, suggesting that gender differences in brain activity were not due to differences in these measures of phenomenological experience. Consistent with our predictions, the fMRI results revealed that males showed a greater difference in functional activity associated with the rich experience of SenseCam vs verbal cues, than did females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981611"}
{"pmid": "20981613", "title": "Comparative antioxidant activities and synergism of resveratrol and oxyresveratrol.", "content": "Comparative antioxidant activities and synergism of resveratrol and oxyresveratrol. Resveratrol (1) and oxyresveratrol (2) are phytoalexins with antioxidant activities (AAs) and proposed effects against several pathological processes. The main objective of this study was to provide a novel, comparative assessment of their AAs, and to test for potential synergism in their combined activities, or in combination with another phytochemical antioxidant, curcumin (3). The phytochemicals were tested at 10 µM total concentrations in a heme-based assay that involved, as the final step, quantification of tetramethyl-phenylene-diamine oxidation. Significant AAs were observed for both 1 and 2, 27-33% inhibition of oxidation (p < 0.05 relative to non-phytochemical control). The combination of 1 and 2 in the same assay (5 µM each) suggested a moderate synergistic effect of about 10% (41% inhibition of oxidation by 1/2 under the same conditions as for 1 and 2 separately). Combinations of 1/3 and 2/3 were also synergistic, but 1/3 had a two-fold greater AA (p < 0.05) than 2/3 (or 1/2). Our results indicate that (i) 1 and 2 are effective antioxidants in the assay, (ii) in combination, their AAs can synergise, and (iii) in relation to 2, 1 has a much greater synergistic potential with 3. The latter suggests different synergy mechanisms of the curcuminoid with each of the two stilbene phytoalexins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981613"}
{"pmid": "20981614", "title": "Chemical composition and biological assays of essential oils of Calamintha nepeta (L.) Savi subsp. nepeta (Lamiaceae).", "content": "Chemical composition and biological assays of essential oils of Calamintha nepeta (L.) Savi subsp. nepeta (Lamiaceae). Aerial parts of wild Calamintha nepeta (L.) Savi subsp. nepeta growing spontaneously on the Mediterranean coast (Sardinia Island, Italy) and on the Atlantic coast (Portugal) were used as a matrix for the supercritical extraction of volatile oil with CO(2). The collected extracts were analysed by GC-FID and GC-MS methods and their compositions were compared with that of the essential oil isolated by hydrodistillation, but the differences were not relevant. A strong chemical variability was observed in the essential oils depending on the origin of the samples. The results showed the presence of two chemotypes of C. nepeta. In all Italian samples, pulegone, piperitenone oxide and piperitenone were the main components (64.4-39.9%; 2.5-19.1%; 6.4-7.7%); conversely, the oil extracted from Portuguese C. nepeta is predominantly composed of isomenthone (35.8-51.3%), 1,8-cineole (21.1-21.4%) and trans-isopulegone (7.8-6.0%). The minimal inhibitory concentration (MIC) and the minimal lethal concentration (MLC) were used to evaluate the antifungal activity of the oils against Candida albicans, Candida tropicalis, Candida krusei, Candida guillermondii, Candida parapsilosis, Cryptococcus neoformans, Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum canis, Microsporum gypseum, Epidermophyton floccosum, Aspergillus niger, Aspergillus fumigatus and Aspergillus flavus. The Italian oil, rich in pulegone, exhibited significant antifungal activity against Aspergillus and dermatophyte strains, with MIC values of 0.32-1.25 µL mL(-1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981614"}
{"pmid": "20981615", "title": "A cardiac glucoside with in vitro anti-HIV activity isolated from Elaeodendron croceum.", "content": "A cardiac glucoside with in vitro anti-HIV activity isolated from Elaeodendron croceum. Human immunodeficiency virus (HIV) affects more than 40 million people worldwide and more than 5 million in South Africa alone. There is no cure for the disease yet, and novel effective drugs need to be discovered to make any progress in combating the disease. Twelve extracts from indigenous South African plants were analysed, of which Elaeodendron croceum showed potent inhibition of transcription factors and a recombinant HIV strain in an MT-2 VSV-pseudotyped recombinant virus assay at 100 ng mL(-1). Bioassay guided isolation of an ethanolic extract of E. croceum yielded a well-known digitoxigenin-glucoside as the only active compound. It showed significant inhibition (90%) at 0.2 µM. The in vitro toxicity of digitoxigenin-glucoside proved to be quite low, and its therapeutic index was 250. This observation indicates that digitoxigenin-glucoside could represent a potential pharmacophore for the treatment of HIV from natural sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981615"}
{"pmid": "20981616", "title": "Inhibitory effect of silibinin on tumour necrosis factor-alpha and hydrogen peroxide production by human monocytes.", "content": "Inhibitory effect of silibinin on tumour necrosis factor-alpha and hydrogen peroxide production by human monocytes. Silibinin is a chemically defined flavonoid and the main active component of silymarin, a polyphenolic complex from Silybum marianum, which has anti-inflammatory, hepatoprotective and anticarcinogenic properties. Monocytes obtained from healthy individuals were incubated with silibinin to evaluate cell viability, hydrogen peroxide (H(2)O(2)) release and tumour necrosis factor-alpha (TNF-α) production by these cells. The duration of treatment and different silibinin concentrations had no significant effect on cell viability. Monocytes showed a dose-dependent inhibitory effect on H(2)O(2) release by phorbol myristate acetate-stimulated monocytes in silibinin concentrations ranging from 6.25 to 50 µg mL(-1). Significant inhibition of TNF-α production by lipopolysaccharide-stimulated monocytes was observed at concentrations of 12.5, 50 and 100 µg mL(-1) of silibinin. These results suggest that silibinin exerts antioxidant and anti-inflammatory properties on human monocytes through an inhibitory effect on H(2)O(2) release and on TNF-α production, respectively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981616"}
{"pmid": "20981617", "title": "Antiplasmodial activity of three bisbenzylisoquinoline alkaloids from the tuber of Stephania rotunda.", "content": "Antiplasmodial activity of three bisbenzylisoquinoline alkaloids from the tuber of Stephania rotunda. Three bisbenzylisoquinoline alkaloids were isolated for the first time from Stephania rotunda tuber. Their structures were elucidated by spectroscopic methods and their antiplasmodial activity was investigated in vitro on chloroquine resistant Plasmodium falciparum strain W2. These alkaloids were identified as 2-norcepharanthine (1), cepharanoline (2) and fangchinoline (3). In vitro, they displayed significant antiplasmodial activity with inhibitory concentration 50 values of 0.3, 0.2 and 0.3 µM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981617"}
{"pmid": "20981618", "title": "Hypoglycaemic effects of tea extracts and ent-kaurenoic acid from Smallanthus sonchifolius.", "content": "Hypoglycaemic effects of tea extracts and ent-kaurenoic acid from Smallanthus sonchifolius. Hypoglycaemic activity was observed in normoglycaemic mice orally administered with the aqueous Smallanthus sonchifolius leaf tea extract, alloxan-induced diabetic mice orally administered with ent-kaurenoic acid (1), and normoglycaemic mice intraperitoneally administered with 1 from S. sonchifolius leaves. A single dose administration of 50 mg kg(-1) BW yacon leaf tea extract demonstrated immediate but relatively short hypoglycaemic activity, with significant effects observed during 1-2 h. Similarly, administration with 100 mg kg(-1) BW yacon leaf tea extract obtained by heavy stirring in hot water demonstrated a more potent activity compared to the positive control at 1.5-2.0 h. Oral administration of 1 did not affect the blood glucose level of the alloxan-induced diabetic mice, but a single intraperitonial injection of 10 mg kg(-1) BW in normoglycaemic mice had consistent percent blood glucose reduction persisting from 1 to 2 h observation periods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981618"}
{"pmid": "20981619", "title": "Isolation of bioactive allelochemicals from sunflower (variety Suncross-42) through fractionation-guided bioassays.", "content": "Isolation of bioactive allelochemicals from sunflower (variety Suncross-42) through fractionation-guided bioassays. Plants are rich source of biologically active allelochemicals. However, natural product discovery is not an easy task. Many problems encountered during this laborious practice can be overcome through the modification of preliminary trials. Bioassay-directed isolation of active plant compounds can increase efficiency by eliminating many of the problems encountered. This strategy avoids unnecessary compounds, concentrating on potential components and thus reducing the cost and time required. In this study, a crude aqueous extract of sunflower leaves was fractionated through high performance liquid chromatography. The isolated fractions were checked against Chenopodium album and Rumex dentatus. The fraction found active against two selected weeds was re-fractionated, and the active components were checked for their composition. Thin layer chromatography isolated a range of phenolics, whereas the presence of bioactive terpenoids was confirmed through mass spectroscopy and nuclear magnetic resonance spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981619"}
{"pmid": "20981620", "title": "White matter changes in patients with hypoxic amnesia.", "content": "White matter changes in patients with hypoxic amnesia. A deficit of declarative memory is a common sequela after a hypoxic episode. While the role of gray matter changes (i.e., atrophy of hippocampal formation) as mainly responsible for memory loss has been emphasized, the role of the white matter damage has so far been neglected. The present study was aimed at evaluating whether white matter damage, within the neural circuitry responsible for declarative memory functioning, is present in anoxic patients. We assessed, by means of voxel-based morphometry, the integrity of white matter regions in five patients with hypoxic amnesia. When anoxic patients were compared to healthy controls, significantly less white matter density was detected in the fornix, anterior portion of the cingulum bundle and uncinate fasciculus bilaterally. We conclude that cerebral hypoxia may alter, together with the hippocampi, the integrity of white matter fibers throughout the memory-limbic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981620"}
{"pmid": "20981621", "title": "Peer-relationship difficulties in children with brain injuries: comparisons with children in mental health services and healthy controls.", "content": "Peer-relationship difficulties in children with brain injuries: comparisons with children in mental health services and healthy controls. Positive peer relationships are essential in healthy development. The prevalence of peer-relationship problems in children after acquired brain injury (ABI) has yet to be explored, although ABI does inevitably impact upon peer interactions. We aimed to explore how peer-relationships and emotional distress after ABI may differ from the levels reported by healthy children or mental health controls. Parents of 214 children (137 \"healthy\" children, 27 children using mental health services and 40 children with ABI) aged 9-15 years participated. A questionnaire measure of peer-relationship functioning and emotional distress was completed. Children with ABI experienced a greater degree of peer-relationship difficulties and emotional distress than healthy controls. No difference was found in reported peer relationship difficulties or emotional distress between ABI children and the children accessing mental health services. We conclude that emotional distress and co-occurring peer-relationship difficulties are as prevalent in a population of children after ABI as may be expected in a population of children under the care of mental health services, yet, unlike the latter group, appropriate intervention services are not commonly available. Interventions that aim to enhance peer relationships after childhood ABI may provide an essential resource to the benefit of outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981621"}
{"pmid": "20981622", "title": "Brain injury beliefs, self-awareness, and coping: a preliminary cluster analytic study based within the self-regulatory model.", "content": "Brain injury beliefs, self-awareness, and coping: a preliminary cluster analytic study based within the self-regulatory model. The interplay between individuals' subjective beliefs about traumatic brain injury, their coping style and their self-awareness might provide a more helpful guide to rehabilitation goals than looking at these factors in isolation. We therefore conducted a preliminary study to determine whether the Self-Regulatory Model can identify different clusters of individuals according to belief schemata, and to explore whether clusters differed across measures of coping and self-awareness. The Illness Perception Questionnaire-Revised was administered to 37 participants with severe traumatic brain injury (TBI), along with the Ways of Coping Checklist-Revised and the European Brain Injury Questionnaire. Clinicians also rated clients' level of difficulties using the latter scale, and the discrepancy between client and clinician scores was used as a measure of self-awareness. Hierarchical cluster analysis distinguished three groups based on profiles of subjective beliefs about TBI, labelled \"low control/ambivalent\", \"high salience\", and \"high optimism\". The high salience group was characterised by beliefs about serious consequences of the injury and greater self-awareness, and reported a greater range of coping strategies. The other two groups showed lower levels of awareness but differed in coping styles, with the low control/ambivalent group showing a trend towards more avoidance coping against a background of lower perceived control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981622"}
{"pmid": "20981623", "title": "Associations between authoritative parenting and the sun exposure and sun protective behaviours of adolescents and their friends.", "content": "Associations between authoritative parenting and the sun exposure and sun protective behaviours of adolescents and their friends. Associations between the sun exposure and sun protective behaviours of adolescents and their friends were examined along with the role played by authoritative parenting and other family and peer socialisation factors. Four hundred and two adolescents (198 males, 204 females) participated in the research. It was found that these adolescents and their friends shared similar sun exposure and sun protective behaviours and had similar parenting backgrounds. Parental authoritativeness was positively associated with the use of sun protection, even after the effects of other familial and peer variables were controlled, but not with the time spent sunbathing which was associated with friends' behaviours. The theoretical and practical implications of these findings are discussed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981623"}
{"pmid": "20981624", "title": "Therapists' and clients' significant experiences underlying psychotherapy discourse.", "content": "Therapists' and clients' significant experiences underlying psychotherapy discourse. This article complements the narrative research that focuses on the process and content of what is said in psychotherapy by examining clients' and therapists' significant experiences beneath the in-session discourse. Toward this end, the authors recorded one midtherapy session from each of four dyads, and the therapist and client from each dyad were then interviewed using an interpersonal process recall method. Participants were asked what they experienced as significant during the session and to describe their rationale for that selection. Descriptions of these experiences were organized into categories using an inductive method. An analysis of therapist- and client-originated categories was conducted to elucidate the often unspoken concerns of participants. The range of internal experiences that underlie narration in psychotherapy is explicated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981624"}
{"pmid": "20981625", "title": "A dynamic look at narrative change in psychotherapy: a case study tracking innovative moments and protonarratives using state space grids.", "content": "A dynamic look at narrative change in psychotherapy: a case study tracking innovative moments and protonarratives using state space grids. This study aims to further the understanding of how innovative moments (IMs), which are exceptions to a client's problematic self-narrative in the therapy dialogue, progress to the construction of a new self-narrative, leading to successful psychotherapy. The authors' research strategy involved tracking IMs, and the themes expressed therein (or protonarratives), and analysing the dynamic relation between IMs and protonarratives within and across sessions using state space grids in a good-outcome case of constructivist psychotherapy. The concept of protonarrative helped explain how IMs transform a problematic self-narrative into a new, more flexible, self-narrative. The increased flexibility of the new self-narrative was manifested as an increase in the diversity of IM types and of protonarratives. Results suggest that new self-narratives may develop through the elaboration of protonarratives present in IMs, yielding an organizing framework that is more flexible than the problematic self-narrative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981625"}
{"pmid": "20981626", "title": "The role of mutual in-feeding in maintaining problematic self-narratives: exploring one path to therapeutic failure.", "content": "The role of mutual in-feeding in maintaining problematic self-narratives: exploring one path to therapeutic failure. According to the author's narrative model of change, clients may maintain a problematic self-stability across therapy, leading to therapeutic failure, by a mutual in-feeding process, which involves a cyclical movement between two opposing parts of the self. During innovative moments (IMs) in the therapy dialogue, clients' dominant self-narrative is interrupted by exceptions to that self-narrative, but subsequently the dominant self-narrative returns. The authors identified return-to-the-problem markers (RPMs), which are empirical indicators of the mutual in-feeding process, in passages containing IMs in 10 cases of narrative therapy (five good-outcome cases and five poor-outcome cases) with females who were victims of intimate violence. The poor-outcome group had a significantly higher percentage of IMs with RPMs than the good-outcome group. The results suggest that therapeutic failures may reflect a systematic return to a dominant self-narrative after the emergence of novelties (IMs).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981626"}
{"pmid": "20981628", "title": "Developmental social neuroscience: an introduction.", "content": "Developmental social neuroscience: an introduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981628"}
{"pmid": "20981629", "title": "Age-related valence-based reversal in recruitment of medial prefrontal cortex on a visual search task.", "content": "Age-related valence-based reversal in recruitment of medial prefrontal cortex on a visual search task. Previous behavioral research has revealed a positivity effect that occurs with aging, with older adults focusing more on positive information and less on negative emotional stimuli as compared to young adults. Questions have been raised as to whether this effect exists in the rapid detection of information or whether it operates only at later stages of processing. In the present study, we used eye-tracking and neuroimaging methodologies to examine whether the two age groups accomplished the detection of emotional information on a visual search task using the same mechanisms. Eye-tracking results revealed no significant age differences in detection or viewing time of emotional targets as a function of valence. Despite their general similarity in task performance, neuroimaging results revealed an age-related valence-based reversal in medial prefrontal cortex (MPFC) activity, with detection of negative compared to positive targets activating the MPFC more for younger adults, and detection of positive compared to negative targets activating the MPFC more for older adults. These results suggest that age-related valence reversals in neural activity can exist even on tasks that require only relatively automatic processing of emotional information.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981629"}
{"pmid": "20981632", "title": "Mapping temporal constructs: actions reveal that time is a place.", "content": "Mapping temporal constructs: actions reveal that time is a place. Many languages employ metaphors that associate temporal constructs with locations in space (e.g., back in the old days). However, whether such space-time mappings extend beyond the linguistic domain has received little empirical attention. Noting that motor action represents a pathway through which the integration of spatial and temporal information can be revealed, the current work examined the dynamics of hand movements during a time-classification task. Results revealed that when participants were instructed to process information pertaining to the past (or future), their movements were drawn towards the left (or right). This affirms that spatiotemporal processing is grounded in the sensory-motor systems that regulate human movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981632"}
{"pmid": "20981631", "title": "Association between objects and body parts mediated by function.", "content": "Association between objects and body parts mediated by function. Recent accounts of conceptual knowledge suggest that the specific gestures/actions that should be performed in order to use an object for its intended function are an integral part of its mental representation. If this is true, then the information regarding which body part needs activating to interact with the object should also be part of such representation. Starting from the assumption that not only artefacts (i.e., tools), but also natural objects (i.e., fruits and vegetables) have a function, the present study investigates the existence of a link between a specific object and the effector involved in its use. The Implicit Association Test (IAT) paradigm was adopted to test for an association between natural objects and mouth, and between artefacts and hand (Experiment 1) or foot (Experiment 2). Results showed selective links between objects and effectors, based on which body part is needed to carry out the object's function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981631"}
{"pmid": "20981630", "title": "Auditory confrontation naming in Alzheimer's disease.", "content": "Auditory confrontation naming in Alzheimer's disease. Naming is a fundamental aspect of language and is virtually always assessed with visual confrontation tests. Tests of the ability to name objects by their characteristic sounds would be particularly useful in the assessment of visually impaired patients, and may be particularly sensitive in Alzheimer's disease (AD). We developed an auditory naming task, requiring the identification of the source of environmental sounds (i.e., animal calls, musical instruments, vehicles) and multiple-choice recognition of those not identified. In two separate studies mild-to-moderate AD patients performed more poorly than cognitively normal elderly on the auditory naming task. This task was also more difficult than two versions of a comparable visual naming task, and correlated more highly with Mini-Mental State Exam score. Internal consistency reliability was acceptable, although ROC analysis revealed auditory naming to be slightly less successful than visual confrontation naming in discriminating AD patients from normal participants. Nonetheless, our auditory naming task may prove useful in research and clinical practice, especially with visually impaired patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981630"}
{"pmid": "20981633", "title": "The multidimensionality of \"pains of imprisonment\" among incarcerated women in Israel.", "content": "The multidimensionality of \"pains of imprisonment\" among incarcerated women in Israel. This study re-examined Gresham Sykes's initial conceptualization of \"pains of imprisonment\" as it applied to women inmates. It contextualized these pains within the women's social experiences both inside and outside the only women's prison in Israel. Semi-structured interviews with 42 female prisoners were conducted. Two counter-themes emerged from our analysis. The first one portrayed prison as punishment, a \"painful condition,\" a stressful event that included deprivation, negative meaning, suffering, and pain. The opposite--and more dominant--theme framed incarceration as a positive experience, during which the prisoners received nurturing, care, and treatment, which they had not been afforded in the outside world. We found that \"pains of imprisonment\" was a multidimensional and complex phenomena that included contradicting emotions, thoughts, and behaviors. \"Pains of imprisonment\" was part of a larger group of pains that extended beyond the time and place of prison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981633"}
{"pmid": "20981634", "title": "Female disclosure of HIV-positive serostatus to sex partners: a two-city study.", "content": "Female disclosure of HIV-positive serostatus to sex partners: a two-city study. The aims of this article are (1) to describe the prevalence of disclosure of HIV serostatus to sex partners among a racially/ethnically diverse sample of HIV-positive women living in Hawai'i and Seattle, Washington; and (2) to examine factors related to disclosure and condom use with those sex partners. HIV-positive women have difficulties consistently disclosing serostatus to sex partners and using condoms. Little is known about the disclosure practices of women from Hawai'i or Seattle. A cross-sectional design with convenience and snowball sampling was used, and up to three recent sex partner experiences were assessed among the HIV-positive participants (N = 84). A total of 133 recent sex partners were reported, with disclosure and condom use frequencies of 75.2 and 59.9%, respectively. Women who knew when it was safe to disclose were more likely to disclose. Women who disclosed to recent sex partners were less likely to use condoms, while those in casual/anonymous partnerships were more likely to use condoms. Hawaiian/part Hawaiian women had the lowest proportion of condom use. Health care personnel should routinely discuss disclosure and sexual transmission risk behaviors with seropositive women and offer strategies to enhance condom use, especially among those in committed partnerships. Culturally tailored interventions focused on strengthening efficacy beliefs for disclosure and condom use in Native Hawaiians are needed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981634"}
{"pmid": "20981635", "title": "Negotiating competing discourses: the decision to take menopausal hormone therapy following surgical menopause.", "content": "Negotiating competing discourses: the decision to take menopausal hormone therapy following surgical menopause. The aim of this study was to examine women's reports of negotiation and decision-making regarding use of menopausal hormone therapy after hysterectomy. Women who have experienced surgical menopause have more intense menopausal symptoms than women who have natural menopause and are often prescribed menopausal hormone therapy. Over the past decade acceptance of use of menopausal hormone therapy has been challenged by publications indicating its associated risks. Foucauldian discourse analysis was used to examine the discourses influencing women's experiences of early menopause precipitated by surgery and their decision-making regarding the use of menopausal hormone therapy. The project investigated via semi-structured interviews the perceptions and experiences of 30 New Zealand women aged 45-65 years who had undergone surgical menopause. The predominant discourses within which the participants' descriptions of their experience were embedded were: (a) new public health, (b) medical, and (c) lay moral judgment. Their health keeping/management practices were influenced by moral imperatives for quality of life, managing risk, and taking care of oneself. The use of menopausal hormone therapy for surgical menopause provides an example of the infiltration of public health discourse into lay judgments and influenced people to identify potential lifestyle problems and direct them to medicine and pharmacology as moral imperatives; and how women resist these discourses in various/particular ways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981635"}
{"pmid": "20981637", "title": "\"A waste of time\": Hispanic women's attitudes toward physical activity.", "content": "\"A waste of time\": Hispanic women's attitudes toward physical activity. Despite a lack of studies on Hispanic midlife women's physical activity, the existing studies have indicated that Hispanics' ethnic-specific attitudes toward physical activity contributed to their lack of physical activity. However, little is still clearly known about Hispanic midlife women's attitudes toward physical activity. The purpose of this study was to explore Hispanic midlife women's attitudes toward physical activity using a feminist perspective. The study was a 6-month qualitative online forum among 23 Hispanic women who were recruited through Internet communities/groups. The data were collected using 17 online forum topics on attitudes toward physical activity and ethnic-specific contexts. The data were analyzed using thematic analysis. Three major themes emerged from the data analysis process: (a) \"family first, no time for myself,\" (b) \"little exercise, but naturally healthy,\" and (c) \"dad died of a heart attack.\" Although some of the women perceived the importance of physical activity due to their family history of chronic diseases, the study participants thought that physical activity would be a waste of time in their busy daily schedules. These findings provided directions for future health care practice and research to increase physical activity among Hispanic midlife women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981637"}
{"pmid": "20981636", "title": "Maternal stress, physical activity, and body mass index during new mothers' first year postpartum.", "content": "Maternal stress, physical activity, and body mass index during new mothers' first year postpartum. We evaluated associations of parenting stress, including depressive symptoms, with 51 first-time mothers' light and moderate physical activity and body mass index during the first year postpartum. The Parenting Stress Index and 24-hour physical activity recalls were completed during the first year postpartum (mean time elapsed since birth: 6 months). Direct relationships between identified variables were tested, and then hierarchical linear regression was used to assess hypothesized relationships among body mass index, physical activity, and parenting stress. Effects of parenting stress on the relationships between postpartum body mass index, light physical activity, and moderate physical activity were evaluated after controlling for factors known to be associated with overweight and low levels of physical activity in women. Mean postpartum body mass index = 27.4 kg/m² ± 7.7, range = 18-50 kg/m². Mean reported hours of light physical activity = 11.2 ± 3.0, and moderate physical activity = 4.5 ± 3.0 per day. Postpartum body mass index was not associated with parenting stress, but was positively related to higher pre-pregnancy body mass index (r = .89, p < .01) and light physical activity (r = .32, p < .05), and was negatively related to moderate physical activity (r = -25, p < .08). Higher postpartum body mass index (β = .27, p < .05), less concern regarding parenting competence (β = -.95, p < .001), and more depressive symptoms (β = .66, p < .01) were associated with more light physical activity (R² = .48, p < .001). More moderate physical activity (R² = .45, p < .001) was associated with lower postpartum body mass index (β = -.27, p < .05), more concern about parenting competence (β = 1.0, p < .001), and less depressive symptoms (β = -.68, p < .01). Higher postpartum body mass index (R² = .89, p < .001) was associated with higher pre-pregnancy body mass index (β = .99, p < .001), more pregnancy weight gain (β = .22, p < .001), less attachment (β = -.68, p < .01), and less social isolation (β = -.13, p < .02). These data suggest that interventions that target parenting stress and depressive symptoms in addition to physical activity are needed to prevent development of overweight in new mothers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981636"}
{"pmid": "20981639", "title": "The effect of comprehensive infection control measures on the rate of late-onset bloodstream infections in very low-birth-weight infants.", "content": "The effect of comprehensive infection control measures on the rate of late-onset bloodstream infections in very low-birth-weight infants. Late-onset bloodstream infection (LOBI) is a significant problem in very low-birth-weight (VLBW) infants and can lead to increased mortality and morbidity. The incidence of LOBI in VLBW infants in our unit was >35% before 2004, much higher than 20% reported in other studies. A comprehensive infection control measure was introduced in our unit in 2005. Here we report the effects of comprehensive infection control measures on the rate of LOBI in VLBW infants. Infants in the preintervention group (born 2001 to 2004) were compared with the intervention group (born 2005 to 2008) for baseline demographics, risk factors for infection, and the rate of LOBI. LOBI was defined as a positive blood and/or cerebrospinal fluid culture after 3 days of life. Three hundred thirty-four VLBW infants were admitted to our unit during the preintervention period and 303 during the intervention period. There was no significant difference in baseline demographics and risk factors for LOBI between the two groups. The incidence of LOBI was significantly reduced from 38% before intervention to 23% after intervention ( P < 0.001). Comprehensive infection control measures significantly reduced the rate of LOBI in VLBW infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981639"}
{"pmid": "20981638", "title": "Perspectives on Pap test follow-up care among rural Appalachian women.", "content": "Perspectives on Pap test follow-up care among rural Appalachian women. Approximately one- to three-quarters of women notified of abnormal Pap test results do not receive appropriate follow-up care, dramatically elevating their risk for invasive cervical cancer. We explored barriers to and facilitators of follow-up care for women in two counties in Appalachian Kentucky, where invasive cervical cancer incidence and mortality are significantly higher than the national average. In-depth interviews were conducted among 27 Appalachian women and seven local health department personnel. Those who had been told of an atypical Pap test result tended to have one of three reactions: (1) not alarmed and generally did not obtain follow-up care; (2) alarmed and obtained follow-up care; or (3) alarmed, but did not obtain care. Each of these typologies appeared to be shaped by a differing set of three categories of influences: personal factors; procedure/provider/system factors; and ecological/community factors. Recommendations to increase appropriate follow-up care included pursuing research on explanations for these typologies and developing tailored interventions specific to women in each of the response types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981638"}
{"pmid": "20981640", "title": "Mild intraoperative hypothermia reduces free tissue transfer thrombosis.", "content": "Mild intraoperative hypothermia reduces free tissue transfer thrombosis. Patients undergoing free tissue transfer are particularly susceptible to hypothermia. The goal was to investigate the impact of intraoperative core body temperature on free flap thrombosis. Two hundred twelve cases of free flap reconstruction at Yale-New Haven Hospital between 1992 and 2008 were reviewed. Free flap thrombosis was defined by complete flap necrosis or direct visualization of arterial or venous thrombosis. Temperature measurements were calibrated to bladder temperatures as measured by Foley catheter sensor. Through logistic regression analysis, maximum and minimum intraoperative temperatures were determined to be statistically significant predictors of free flap thrombosis. The optimal temperature was calculated to be 36.2 °C, and maximum intraoperative temperatures between 36.0 °C and 36.4 °C showed lower thrombosis rates than super-warmed patients ( P < 0.03). Therefore, free flap patients should be mildly hypothermic at 36.0 °C to 36.4 °C, compared with normothermia at 37.5 °C, as measured in the bladder. A prospective randomized trial investigating thrombosis rates and intraoperative temperature should be undertaken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981640"}
{"pmid": "20981642", "title": "Relationship between baseline severity of depression and antidepressant treatment outcome.", "content": "Relationship between baseline severity of depression and antidepressant treatment outcome. Assessment of depression severity is of key importance, since several clinical guidelines recommend choice of treatment dependent on the depression severity grade. Using different tools to assess baseline severity may result in different outcomes. This paper describes the results of a multicentre, naturalistic study investigating the relationship between depression symptom severity (using 4 different measures of symptom severity) and clinical outcome among patients hospitalised for depression (N=1 014). Moreover, the impact of differences between methods of measuring depression severity has been investigated. Statistical analyses (univariate measurements, logistic regression models) were conducted to detect coherences and differences between the various methods of severity categorisation. Results revealed different associations between outcome and classification methods. Response or remission rates varied if baseline severity was assessed by different instruments. Moreover, the number of responders increased with higher baseline severity grades of depression, whereas the number of remitters decreased. Additional analyses dependent on outcome criteria using continuous instead of categorical data revealed similar results. Baseline severity may be only one of many other important clinical variables that mediate clinical outcome, but it is surely an important one deserving further research and consideration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981642"}
{"pmid": "20981644", "title": "Laparoscopic excision of splenic cysts: a comparison to the open approach.", "content": "Laparoscopic excision of splenic cysts: a comparison to the open approach. The aim of this study was to evaluate the outcomes following excision of splenic cysts in children. A retrospective chart review of all patients who underwent excision of a splenic cyst between 1990 and 2007 was performed. Age, cyst etiology, cyst size, preoperative imaging, and operative approach were evaluated. Outcome variables included length of postoperative hospitalization, cyst recurrence, postoperative imaging, the histologic lining of the cyst, and the need for additional procedures. During this 17-year period, 9 patients underwent excision of a splenic cyst. Four underwent an open operation and 5 had a laparoscopic procedure. In the open group, 2 patients underwent splenectomy, one patient had a partial splenectomy, and one cyst was aspirated and marsupialized. In the laparoscopic group, 4 patients underwent complete excision of the cyst and 1 underwent resection of the outer wall. The mean age was 12.3 years. Computed tomography was performed preoperatively in 8 patients and one child had an ultrasound study. The most common symptom was abdominal pain in 6 patients. Four patients had a history of recent abdominal trauma. The mean length of postoperative hospitalization was 2.75 days for the open group and 1.6 days for the laparoscopic cohort. One patient in the laparoscopic group had a recurrence. To date, no additional operations have been performed. Laparoscopic splenic cyst excision is comparable to open cyst excision and results in a decreased length of postoperative hospitalization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981644"}
{"pmid": "20981645", "title": "Evaluation of the necessity of contrast in the follow-up MRI of schwannomas.", "content": "Evaluation of the necessity of contrast in the follow-up MRI of schwannomas. The purpose of our study was to determine whether gadolinium is necessary in follow-up MRIs for evaluating vestibular schwannomas. A retrospective analysis of 49 magnetic resonance imaging (MRI) examinations of 20 vestibular schwannoma patients was performed. Patients received between 1 and 4 follow-up scans, and the mean follow-up period was 15.3 months. Two radiologists independently reviewed the initial and follow-up MRI examinations. Tumor measurements obtained using the constructive interference in steady state (CISS) and contrast-enhanced T1-weighted (T1W) sequences were compared. Both radiologists used both of the sequences to analyze any differences in the tumor sizes measured in consecutive MRI scans. The linear anteroposterior and transverse tumor diameter measurements obtained by the two observers using both sequences were strongly correlated (r = 0.962-0.987, P < 0.001). The observers agreed to a very high degree when detecting changes in the tumor size using the CISS sequence (κ = 0.902, P = 0.0001), whereas the agreement with the contrast-enhanced T1W sequence was good but not as good (κ = 0.706, P = 0.001). CISS, as a contrast-free sequence, may be an option in regular follow-up MRIs of vestibular schwannomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981645"}
{"pmid": "20981646", "title": "Malignant fibrous histiocytoma of the mandible.", "content": "Malignant fibrous histiocytoma of the mandible. Malignant fibrous histiocytoma (MFH) of the mandible is rare. We describe a case of MFH of the mandible with metastatic disease to the lungs. To our knowledge only 30 cases have been reported prior to the present case. In previously reported cases, there was a strong tendency for the posterior portion of the mandible to be affected by MFH; ours is only the second reported case involving the anterior portion of the mandible. We review the diagnosis, pathology, and treatment of this rare malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981646"}
{"pmid": "20981647", "title": "Primary carcinoid tumor of the frontal sinus: A case report.", "content": "Primary carcinoid tumor of the frontal sinus: A case report. Carcinoid tumors are rare, indolent, neuroendocrine tumors that are most commonly found in the gastrointestinal tract and lungs. They occasionally develop in the head and neck, either as a primary tumor or, more commonly, as a metastasis. The most common sites of head and neck carcinoids are the larynx and middle ear. Only a few cases of carcinoid in the nasal cavity and paranasal sinuses have been reported. We describe a case of primary typical carcinoid of the frontal sinus in a 61-year-old man, and we review the clinical, imaging, surgical, and histochemical findings in this case. The patient was treated with endoscopic resection. A subsequent workup for metastatic and occult primary disease was negative, confirming that the frontal sinus was the primary source. At follow-up 12 months postoperatively, the patient remained without disease. To the best of our knowledge, this is the first report of a primary typical carcinoid tumor originating in the frontal sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981647"}
{"pmid": "20981648", "title": "Otolaryngologic uses for spinal drains.", "content": "Otolaryngologic uses for spinal drains. Cerebrospinal fluid (CSF) fistulae have been encountered by otolaryngologists often since the advent of modern endoscopic sinus surgery, otologic surgery, and skull base surgery. Treatment of CSF leaks may include bed rest, head-of-bed elevation, stool softeners, external spinal fluid drainage, and surgery. External CSF drainage is accomplished via a lumbar spinal drain. Placement of spinal drains is often performed by neurosurgeons and anesthetists. A few otolaryngologists have been trained in the placement and management of lumbar drains, but at most otolaryngology training institutions, education in lumbar drains is not provided. However, in some circumstances, it may fall to an otolaryngologist to accomplish the task. We believe that every otolaryngologist, from the generalist in private practice to the academic neuro-otologic surgeon, should understand the proper technique for the insertion and management of a lumbar drain. Otolaryngologists should be familiar with the physiologic properties of CSF, the methods used to diagnose fistulae, and the techniques used to repair leaks. External spinal drainage is an important element in the management of CSF fistulae, and it has been used in treating perilymphatic fistulae and \"gushers.\" Much controversy surrounds its routine use. Otolaryngologists need to understand the risks, benefits, and outcomes of spinal drain use in order to decide which patients may benefit from this procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981648"}
{"pmid": "20981649", "title": "Prevalence of complementary and alternative medicine use among a population of head and neck cancer patients: a survey-based study.", "content": "Prevalence of complementary and alternative medicine use among a population of head and neck cancer patients: a survey-based study. We sought to determine the prevalence and patterns of complementary and alternative medicine (CAM) use among head and neck cancer patients who were being treated at an academic otolaryngology practice in the northeastern United States from January 2005 through December 2006. During a 3-month period, we conducted an anonymous survey of 213 new and established patients regarding their use of CAM during their cancer treatment. According to the responses, only 13 of these patients (6.1%) were currently using CAM during treatment. With respect to the various products being taken, 9 patients (69.2% of all CAM users) were taking herbs or supplements. Only 7 patients (53.8%) who used CAM disclosed this fact to their physician during in-office encounters. The most common sources for obtaining CAM were health-food stores, where most patients spent approximately $25 per week. The most frequently cited reason for using CAM was that a particular product had been recommended by family or friends as being potentially helpful. No adverse effects of CAM were reported. We conclude that while CAM use was not very prevalent in this study, patients who did use it were employing modalities with biologic activity that may potentially interact with conventional therapies. Because patients' disclosure of CAM use is frequently not volunteered, otolaryngologists should routinely elicit this information in a highly specific fashion so that we may better serve our unique patient population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981649"}
{"pmid": "20981650", "title": "Concurrent nasal surgery and tympanoplasty in adults.", "content": "Concurrent nasal surgery and tympanoplasty in adults. We conducted a retrospective chart review to determine if performing simultaneous nasal surgery and tympanoplasty jeopardizes tympanic membrane graft survival and the surgical outcome. Our study population consisted of 14 consecutively presenting adults with nasal septal deviation and otologic pathology who had undergone simultaneous nasal and otologic procedures at an academic tertiary care medical center. Surgical procedures included septoplasty and bilateral inferior turbinate submucous reduction with concurrent primary or revision tympanoplasty with or without mastoidectomy and ossicular chain reconstruction. Follow-up ranged from 1.8 to 29.8 months (mean: 12.8 ± 10.8). The primary outcomes measures were tympanic membrane graft survival and surgical success; the latter was defined as an absence of middle ear effusion and a lack of need for pressure-equalization tube placement in patients with intact grafts. We found that 13 of the 14 tympanic membrane grafts (92.9%) survived at the most recent follow-up and that 11 patients (78.6%) achieved an aerated middle ear without the need for a pressure-equalization tube. These rates compare favorably with those quoted in the literature for tympanoplasty performed without concomitant nasal surgery. We conclude that septoplasty can be safely and effectively performed at the same time as tympanoplasty with or without mastoidectomy with no increase in the risk of surgical failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981650"}
{"pmid": "20981651", "title": "Otolaryngologic community-acquired MRSA infections in a suburban private practice.", "content": "Otolaryngologic community-acquired MRSA infections in a suburban private practice. A retrospective review was conducted of all cases of head and neck community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections seen in the senior author's suburban private practice during a 12-month period. An office and hospital chart review was performed for all patients identified with culture-positive CA-MRSA infections. Several parameters were evaluated, including site of infection, prior therapy, imaging, comorbid disease, culture and sensitivities, surgical and medical management, and long-term results. Of the 10 patients identified, 3 had infections of nasal soft tissues, 3 had infections of the lips, 2 had infections of the paranasal sinus, 1 had an infection of the chin, and 1 had a diffuse, hemifacial infection. All patients were managed successfully with a combination of surgical drainage, wound care, and antibiotics. CA-MRSA is a burgeoning problem in otolaryngology. Appropriate management-including early recognition, appropriate empirical therapy, prompt and thorough surgical drainage with culture and sensitivities, correct antibiotic choice, and meticulous postoperative care-appears to offer excellent results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981651"}
{"pmid": "20981652", "title": "An unusual recurrent intrathoracic goiter: Case report.", "content": "An unusual recurrent intrathoracic goiter: Case report. Most intrathoracic goiters are located in the anterior mediastinum, frontal to the recurrent laryngeal nerve and anterolateral to the trachea. Posterior mediastinal goiters account for only 10 to 15% of all intrathoracic goiters and arise from the posterolateral portion of the thyroid gland. We present a case involving a 59-year-old man with history of gradual-onset dyspnea who was referred to us for evaluation of a large mediastinal mass. He had undergone bilateral thyroid lobectomy for a cervical goiter 10 years previously, with no subsequent complications. Contrast-enhanced computed tomography demonstrated a large, well-circumscribed mass extending paratracheally from the thoracic inlet to the posterior mediastinum. The mass was removed via a transcervical and transthoracic approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981652"}
{"pmid": "20981653", "title": "A simple method to cover the donor site of a partial-thickness skin graft: How I do it.", "content": "A simple method to cover the donor site of a partial-thickness skin graft: How I do it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981653"}
{"pmid": "20981654", "title": "Congenital tympanic ring defect presenting as an external auditory canal mass.", "content": "Congenital tympanic ring defect presenting as an external auditory canal mass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981654"}
{"pmid": "20981656", "title": "Publication as a teaching tool.", "content": "Publication as a teaching tool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981656"}
{"pmid": "20981655", "title": "Schneiderian papillomas and carcinomas: a retrospective study with special reference to p53 and p16 tumor suppressor gene expression and association with HPV.", "content": "Schneiderian papillomas and carcinomas: a retrospective study with special reference to p53 and p16 tumor suppressor gene expression and association with HPV. Schneiderian papillomas are uncommon benign tumors of the sinonasal area. They are prone to local aggressiveness and recurrence, and some undergo malignant progression. We analyzed specimens obtained from 67 Chinese patients who had presented to the ENT department of a regional hospital with biopsy-proven schneiderian papilloma. Seven of these patients had either synchronous or metachronous carcinoma, 1 of whom had pure carcinoma in situ. For each case, we documented the morphology, immunohistochemical expression of tumor suppressor genes p53 and p16, and any association with human papillomavirus (HPV) infection as detected by either polymerase chain reaction or in situ hybridization techniques. We found that severe dysplasia and p53 positivity were strongly associated with malignant progression. Association with HPV was demonstrated in 22 of the 67 patients (33%); the association was strongest among patients with exophytic papillomas and carcinomas. The effect of HPV in papilloma oncogenesis probably begins during the early phase, while other factors are responsible for progression to carcinoma. We conclude that p53-positive, dysplastic schneiderian papillomas warrant aggressive surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981655"}
{"pmid": "20981657", "title": "Endoscopic view of a longitudinal cleft concha bullosa.", "content": "Endoscopic view of a longitudinal cleft concha bullosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981657"}
{"pmid": "20981658", "title": "Laryngeal paraganglioma.", "content": "Laryngeal paraganglioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981658"}
{"pmid": "20981659", "title": "Primary osteogenic sarcoma of the maxilla.", "content": "Primary osteogenic sarcoma of the maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981659"}
{"pmid": "20981661", "title": "Neonatal suppurative parotitis.", "content": "Neonatal suppurative parotitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981661"}
{"pmid": "20981662", "title": "Measurements of the facial recess anatomy: implications for sparing the facial nerve and chorda tympani during posterior tympanotomy.", "content": "Measurements of the facial recess anatomy: implications for sparing the facial nerve and chorda tympani during posterior tympanotomy. Posterior tympanotomy is commonly performed through the facial recess to facilitate cochlear implantation. A rare but serious complication of this procedure is paralysis of the facial nerve and/or the chorda tympani. These complications generally occur because of a limited understanding of the anatomy of the facial recess. To help further define this area, we used computer-aided design software to measure (1) the angle between the facial nerve and the chorda tympani nerve and (2) the distance between the takeoff point of the chorda tympani and the posteriormost prominent point of the short process of the incus in 30 cadaveric adult temporal bones. The mean angle was 23.58° (±6.84), and the mean distance was 7.78 mm (±2.68). Our most important finding was that there was a correlation between the two measurements in that the distance tended to be greater when the angle was less than the mean and vice versa. This trend approached but did not quite reach statistical significance (r = -0.248, p = 0.059).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981662"}
{"pmid": "20981663", "title": "Presence of biofilm on adult tracheostomy tubes.", "content": "Presence of biofilm on adult tracheostomy tubes. We conducted a prospective observational study of tracheostomy tubes with three primary goals: (1) to identify the presence and location of bacterial biofilms on adult tubes, (2) to determine how soon after insertion of a tube the presence of a biofilm could be identified, and (3) to identify the bacterial organisms that formed the biofilms on these tubes. Our study materials consisted of 7 adult tracheostomy tubes that had been changed during a routine outpatient clinic visit or hospital consultation. The tubes were examined for the presence of biofilms on the posterior aspect of the outer cannula; also, specimens were obtained from the posterosuperior aspect of the cuff on the 3 tubes that had a cuff. Samples of 2 to 3 mm were taken from each site and analyzed by scanning electron microscopy. Bacterial biofilms were found on 4 of the 7 tubes; they were present on the outer cannula of 3 cuffless tubes that had been inserted 14 days, 4 months, and 2 years previously and on the cuff of 1 tube that had been inserted 10 days previously. The biofilms were composed of gram-positive cocci in pairs that were likely consistent with Staphylococcus epidermidis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981663"}
{"pmid": "20981664", "title": "A rare case of asymptomatic bilateral submandibular gland sialolithiasis: a giant, fistulized calculus on the right and multiple calculi on the left.", "content": "A rare case of asymptomatic bilateral submandibular gland sialolithiasis: a giant, fistulized calculus on the right and multiple calculi on the left. Sialolithiasis is the most common disease of the submandibular gland; sialoliths account for at least 80% of all salivary duct calculi. We present a rare case of asymptomatic bilateral submandibular gland sialoliths. On the right, the patient had a giant (35 × 35 mm) sialolith that had fistulized into the oral cavity. In the left submandibular gland, he had 30 differently sized sialoliths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981664"}
{"pmid": "20981666", "title": "Anionic N-heterocyclic carbenes with N,N'-bis(fluoroaryl) and N,N'-bis(perfluoroaryl) substituents.", "content": "Anionic N-heterocyclic carbenes with N,N'-bis(fluoroaryl) and N,N'-bis(perfluoroaryl) substituents. A series of rhodium complexes, [Rh(cod)(NHC-F(x))(OH(2))] (cod = 1,5-cyclooctadiene; NHC = N-heterocyclic carbene), incorporating anionic N-heterocyclic carbenes with 2-tert-butylmalonyl backbones and 2,6-dimethylphenyl (x = 0), 2,6-difluorophenyl (x = 4), 2,4,6-trifluorophenyl (x = 6), and pentafluorophenyl (x = 10) N,N'-substituents, respectively, has been prepared by deprotonation of the corresponding zwitterionic precursors with potassium hexamethyldisilazide, followed by immediate reaction of the resulting potassium salts with [{RhCl(cod)}(2)]. These complexes could be converted to the related carbonyl derivatives [Rh(CO)(2)(NHC-F(x))(OH(2))] by displacement of the COD ligand with CO. IR and NMR spectroscopy demonstrated that the degree of fluorination of the N-aryl substituents has a considerable influence on the σ-donating and π-accepting properties of the carbene ligands and could be effectively used to tune the electronic properties of the metal center. The carbonyl groups on the carbene ligand backbone provided a particularly sensitive probe for the assessment of the metal-to-ligand π donation. The ortho-fluorine substituents on the N-aryl groups in the carbene ligands interacted with the other ligands on rhodium, determining the conformation of the complexes and creating a pocket suitable for the coordination of water to the metal center. Computational studies were used to explain the influence of the fluorinated N-substituents on the electronic properties of the ligand and evaluate the relative contribution of the σ- and π-interactions to the ligand-metal interaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981666"}
{"pmid": "20981668", "title": "Structure and dynamic features of an intramolecular frustrated Lewis pair.", "content": "Structure and dynamic features of an intramolecular frustrated Lewis pair. Di(mesityl)cyclohexenylphosphine undergoes hydroboration with Piers' borane [HB(C(6)F(5))(2)] to yield the cyclohexylene-anellated frustrated Lewis pair 5. This P/B pair splits H(2) with the formation of the product 4 and adds to the C=O double bond of phenyl isocyanate to yield 6. In the crystal, compound 5 features a puckered four-membered heterocyclic core structure with a long P-B bond (av. 2.197(5) Å). The activation energy of the P-B cleavage of the frustrated Lewis pair 5 was determined by dynamic (19)F NMR spectroscopy at ΔG(≠)(298 K)=12.1±0.3 kcal mol(-1).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981668"}
{"pmid": "20981667", "title": "Probing the influence of an allylic methyl group in zearalenone analogues on binding to Hsp90.", "content": "Probing the influence of an allylic methyl group in zearalenone analogues on binding to Hsp90. By the replacement of an acetate with propionate by means of organic synthesis, a range of zearalenone analogues were prepared that feature an allylic methyl group. For the synthesis of the aliphatic region of the analogues, we used an asymmetric alkylation to yield pentenol derivatives 16 and ent-16. By means of hydroboration the corresponding aldehydes were secured. These were coupled with 2-pentynol derivate 23 by means of a Carreira acetylide addition. Further routine steps led to the sulfones 29 and 45, respectively. After merging them with 2-bromobenzaldehyde 9 in a Julia-Kocienski reaction, metalation, carboxylation, and protecting-group manipulations gave the seco acids 35 and 49. By means of lactonization under Mitsunobu (alcohol activation) or Trost-Kita conditions (carboxyl activation), all four possible macrocyclic ketone stereoisomers were accessible. In all, considering various protecting-group decorations, 16 analogues were obtained and tested for cytotoxicity (L929 mouse fibroblast cell line). Whereas most of the analogues were less active than zearalenone (IC(50)=9.4 μM), the resorcinol derivatives were comparable, with one stereoisomer (40 b) being slightly more active (IC(50)=6.6 μM). These results were also reflected in the binding assays to Hsp90 in which 40 b showed a dissociation constant (K(d)) value of 130 nM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981667"}
{"pmid": "20981665", "title": "Mitochondrial mode of action of a thymidine-based cisplatin analogue breaks resistance in cancer cells.", "content": "Mitochondrial mode of action of a thymidine-based cisplatin analogue breaks resistance in cancer cells. Cisplatin analogue complexes with platinum(II) and palladium(II) starting from 3',5'-diamino-3',5'-dideoxy-thymidines were synthesized, both with the D-erythro- and D-threo configurations. Complexes of the general formula [MCl(2)L] were obtained and characterized. NMR spectroscopic measurements and single crystal X-ray structure analysis showed that the metal centers are coordinated to the ligands by the amino groups in 3'- and 5'-positions and not through the thymine moiety. All ligands and complexes showed no significant in vitro activities except thymiplatin (cis-dichloro(3',5'-diamino-3',5'-dideoxy-D-threo-thymidine)platinum(II)). Detailed in vitro studies on the apoptosis pathway in lymphoma (BJAB), leukemia (NALM-6), and melanoma cells (Mel-HO) as well as on transfected or resistant cell lines were carried out. Thymiplatin significantly induced an apoptotic response, which was found to be associated with the loss of mitochondrial membrane potential and with caspase activation. The activity was shown to be independent of Fas-associated protein with death domain (FADD), but dependent on Bcl-2 expression. As a consequence, for thymiplatin a mitochondrial mode of action could be assigned. Moreover, the compound showed activity in cells resistant to common drugs, such as daunorubicin and vincristin, and showed synergistic effects with doxorubicin, vincristin, cytarabin, and daunorubicin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981665"}
{"pmid": "20981670", "title": "Bimetallic catalysis involving dipalladium(I) and diruthenium(I) complexes.", "content": "Bimetallic catalysis involving dipalladium(I) and diruthenium(I) complexes. Dipalladium(I) and diruthenium(I) compounds bridged by two [{(5,7-dimethyl-1,8-naphthyridin-2-yl)amino}carbonyl]ferrocene (L) ligands have been synthesized. The X-ray structures of [Pd(2)L(2)][BF(4)](2) (1) and [Ru(2)L(2)(CO)(4)][BF(4)](2) (2) reveal dinuclear structures with short metal-metal distances. In both of these structures, naphthyridine bridges the dimetal unit, and the site trans to the metal-metal bond is occupied by weakly coordinating oxygen from the amido fragment. The catalytic utilities of these bimetallic compounds are evaluated. Compound 1 is an excellent catalyst for phosphine-free, Suzuki cross-coupling reactions of aryl bromides with arylboronic acids and provides high yields in short reaction times. Compound 1 is also found to be catalytically active for aryl chlorides, although the corresponding yields are lower. A bimetallic mechanism is proposed, which involves the oxidative addition of aryl bromide across the Pd-Pd bond and the bimetallic reductive elimination of the product. Compound 1 is also an efficient catalyst for the Heck cross-coupling of aryl bromides with styrenes. The mechanism for aldehyde olefination with ethyl diazoacetate (EDA) and PPh(3), catalyzed by 2, has been fully elucidated. It is demonstrated that 2 catalyzes the formation of phosphorane utilizing EDA and PPh(3), which subsequently reacts with aldehyde to produce a new olefin and phosphine oxide. The efficacy of bimetallic complexes in catalytic organic transformations is illustrated in this work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981670"}
{"pmid": "20981669", "title": "C-2 arylation of piperidines through directed transition-metal-catalyzed sp3 C-H activation.", "content": "C-2 arylation of piperidines through directed transition-metal-catalyzed sp3 C-H activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981669"}
{"pmid": "20981671", "title": "Ostensible enzyme promiscuity: alkene cleavage by peroxidases.", "content": "Ostensible enzyme promiscuity: alkene cleavage by peroxidases. Enzyme promiscuity is generally accepted as the ability of an enzyme to catalyse alternate chemical reactions besides the 'natural' one. In this paper peroxidases were shown to catalyse the cleavage of a C=C double bond adjacent to an aromatic moiety for selected substrates at the expense of molecular oxygen at an acidic pH. It was clearly shown that the reaction occurs due to the presence of the enzyme; furthermore, the reactivity was clearly linked to the hemin moiety of the peroxidase. Comparison of the transformations catalysed by peroxidase and by hemin chloride revealed that these two reactions proceed equally fast; additional experiments confirmed that the peptide backbone was not obligatory for the reaction and only a single functional group of the enzyme was required, namely in this case the prosthetic group (hemin). Consequently, we propose to define such a promiscuous activity as 'ostensible enzyme promiscuity'. Thus, we call an activity that is catalysed by an enzyme 'ostensible enzyme promiscuity' if the reactivity can be tracked back to a single catalytic site, which on its own can already perform the reaction equally well in the absence of the peptide backbone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981671"}
{"pmid": "20981674", "title": "Expression profiling of cytogenetically normal acute myeloid leukemia identifies microRNAs that target genes involved in monocytic differentiation.", "content": "Expression profiling of cytogenetically normal acute myeloid leukemia identifies microRNAs that target genes involved in monocytic differentiation. MicroRNAs are short ribonucleic acids (RNAs) that play an important role in many aspects of cellular biology such as differentiation and apoptosis, due to their role in the regulation of gene expression. Using microRNA microarrays, we characterized the microRNA gene expression of 27 patients with acute myeloid leukemia (AML) with normal cytogenetics, focusing on the microRNAs differentially expressed between the M1 and M5 French-American-British (FAB) subtypes. An accurate delineation of these two AML entities was observed based on the expression of 12 microRNAs. We hypothesized that these microRNAs may potentially be involved in the differentiation block of M1 blasts and consequently monocytic differentiation. Using publically available mRNA data and microRNA target prediction software, we identified several key myeloid factors that may be targeted by our candidate microRNAs. The expression changes of the candidate microRNAs during monocytic differentiation of AML cell lines treated with Vitamin D and phorbol 12-myristate 13-acetate were examined. All six candidate microRNAs were significantly down-regulated over the time course by quantitative reverse transcriptase polymerase chain reaction suggesting a link between these microRNAs and monocytic differentiation. To further characterize these microRNAs, we confirmed by luciferase assays that these microRNA target several key myeloid factors such as MAFB, IRF8, and KLF4 identifying a possible mechanism for the control of differentiation by these microRNAs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981674"}
{"pmid": "20981675", "title": "Evidence of persistent neurologic injury following thrombotic thrombocytopenic purpura.", "content": "Evidence of persistent neurologic injury following thrombotic thrombocytopenic purpura. Despite improvements in our understanding of the pathophysiology of thrombotic thrombocytopenic purpura (TTP), little data exist regarding the long-term sequelae following a diagnosis of TTP. We present the results of a comprehensive evaluation of neurologic injury that included a magnetic resonance imaging (MRI), a neurocognitive testing, and an evaluation of health-related quality of life. Twenty-seven patients with a history of idiopathic TTP functioning normally in their activities of daily living were recruited from existing patient cohorts at both the Ohio State University (n 5 12) (Columbus) and the University College London Hospitals (n 5 15) (London, UK). Nine of 23 (39%) of the MRI studies were abnormal; 17/27 (63%) patients demonstrated neurocognitive impairment, particularly in tests of visual learning and memory. Health-related quality of life scores were also significantly lower than age- and gender-matched US norms for both the composite mental component score and physical component score. These data suggest that the prevalence of neurologic findings in TTP patients in remission is quite high and is largely undetected by routine clinical evaluations. Further longitudinal study will be required to define the risk for neurologic injury and the long-term prognosis in patients previously diagnosed with TTP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981675"}
{"pmid": "20981676", "title": "Effective use of rituximab for acquired amegakaryocytic thrombocytopenia.", "content": "Effective use of rituximab for acquired amegakaryocytic thrombocytopenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981676"}
{"pmid": "20981677", "title": "ENERCA clinical recommendations for disease management and prevention of complications of sickle cell disease in children.", "content": "ENERCA clinical recommendations for disease management and prevention of complications of sickle cell disease in children. Universal neonatal screening is performed in the United States, England, the Netherlands, and several cities in Belgium, with selective screening targeted on \"high-risk\" population in France (globally, one quarter of all the babies born in France are screened). Newborns diagnosed with a major sickle cell syndrome (SCD) should be referred to a designated pediatric sickle cell centre, and the parents are informed that their child has SCD; this may be in the sickle cell centre by an expert physician or in the community by an experienced nurse counsellor. The pediatric sickle cell centre should organize the care of the baby.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981677"}
{"pmid": "20981678", "title": "Clinical outcome of patients with acute promyelocytic leukemia and FLT3 mutations.", "content": "Clinical outcome of patients with acute promyelocytic leukemia and FLT3 mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981678"}
{"pmid": "20981679", "title": "Monitoring of minimal residual disease in acute myeloid leukemia with frequent and rare patient-specific NPM1 mutations.", "content": "Monitoring of minimal residual disease in acute myeloid leukemia with frequent and rare patient-specific NPM1 mutations. Nucleophosmin (NPM1) mutations in exon 12 are the most common genetic alternation in cytogenetically normal AML (CN-AML). Although mutation types A, B, and D represent the majority of cases, rare mutation variants of the NPM1 gene in individual patients do occur. In this study, we have evaluated a novel, DNA-based real-time quantitative polymerase chain reaction (RQ-PCR) for the detection of three of the most commonly occurring mutations and for six rare patient-specific mutation types, which represent 28% of all of the NPM1 mutations in our group of 25 CN-AML patients. Furthermore, the prognostic relevance of NPM1-based monitoring of minimal residual disease (MRD) in peripheral blood (PB), bone marrow (BM), and in specific cell subsets (CD34(+), CD34(-), CD34(dim)) of BM were evaluated. In 80% of the evaluable patients, a molecular relapse preceded a hematological relapse. Moreover, in this subset of patients, the molecular relapse occurred at a median of 97 days before the hematological relapse. Our compartment analysis showed a strong correlation between BM and PB (r = 0.907, P < 0.001) as well as a high copy number of mutated NPM1 in CD34(+) BM cells. In conclusion, we have demonstrated applicability of our presented RQ-PCR method for a large percentage of mutated NPM1 patients with CN-AML as well as the usefulness for long-term follow-up monitoring of MRD and the prediction of hematological relapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981679"}
{"pmid": "20981680", "title": "Survival in elderly follicular lymphoma patients who receive frontline chemo-immunotherapy.", "content": "Survival in elderly follicular lymphoma patients who receive frontline chemo-immunotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981680"}
{"pmid": "20981681", "title": "Bone marrow reticulin and collagen content in patients with adult chronic immune thrombocytopenic purpura: a Danish nationwide study.", "content": "Bone marrow reticulin and collagen content in patients with adult chronic immune thrombocytopenic purpura: a Danish nationwide study. We quantified and differentiated reticulin and collagen content in bone marrow specimens from chronic immune thrombocytopenic (ITP) patients and examined the correlation between some clinical characteristics and the fibrosis grading. Through the Danish National Patient Registry, we identified 378 patients with chronic ITP from 1997 until 2007. Of these, 253 (67%) had undergone at least one bone marrow biopsy, and we retrieved the bone marrow specimens from 187 (74%). We graded the bone marrow content of reticulin and collagen according to the Thiele scale (Grade 0-3). We also retrieved information on patients' clinical characteristics. We examined the prevalence of bone marrow fibrosis grading > 0 by patients' age (≤ 75 years and > 75 years), sex, platelet count at baseline (< 30 × 10⁹/L, and ≥ 30 × 10⁹/L), splenomegaly, hepatomegaly, and medications. In total 75 chronic ITP patients (40%) had a bone marrow grading >0. Of these, 72 (39%) had Grade 1 reticulin fibers present. Only three patients (< 2%) had collagen fibers present: two had Grade 2 and one had Grade 3. The prevalence of bone marrow grading > 0 was lower in patients aged > 75 years than ≤ 75 years (prevalence ratio = 0.64, 95% CI: 0.36-1.15) and lower in men than women (prevalence ratio = 0.70, 95% CI: 0.45-1.09), while a baseline platelet count ≥ 30 × 10⁹/L was associated with a higher prevalence of grading > 0 (prevalence ratio = 1.24, 95% CI: 0.81-1.86). Thus, bone marrow reticulin and collagen content in chronic ITP patients may be associated with some clinical characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981681"}
{"pmid": "20981682", "title": "A new species of snub-nosed monkey, genus Rhinopithecus Milne-Edwards, 1872 (Primates, Colobinae), from northern Kachin state, northeastern Myanmar.", "content": "A new species of snub-nosed monkey, genus Rhinopithecus Milne-Edwards, 1872 (Primates, Colobinae), from northern Kachin state, northeastern Myanmar. We describe a snub-nosed monkey that is new to science from the high altitudes of northeastern Kachin state, northeastern Myanmar, the Burmese snub-nosed monkey, Rhinopithecus strykeri sp. nov. Descriptions are based on a skin and skulls of four specimens obtained from local hunters. The new species is geographically isolated from other snub-nosed monkeys and separated from them by two major barriers--the Mekong and the Salween (Thanlwin) rivers. The species is chiefly diagnosed by its almost entirely blackish fur coloration with white fur only on ear tufts, chin beard, and perineal area, and its relatively long tail (140% of head and body length in the adult male). Preliminary surveys and interviews with hunters indicate that the new species is limited in distribution to the Maw River area, a small region of the Salween-N'mai Hka divide in northeastern Kachin state, northeastern Myanmar. The distribution area appears to cover about 270 km(2), and the species may consist of only three groups with a total population of approximately 260-330 individuals. Our data on hunting pressure suggest that the species is Critically Endangered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981682"}
{"pmid": "20981686", "title": "Infant leukemia 2010: a call to action for the west and the \"four Asian Tigers\".", "content": "Infant leukemia 2010: a call to action for the west and the \"four Asian Tigers\".", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981686"}
{"pmid": "20981687", "title": "Outpatient high-dose methotrexate: proceed with extreme caution, if at all.", "content": "Outpatient high-dose methotrexate: proceed with extreme caution, if at all.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981687"}
{"pmid": "20981689", "title": "Correlation between pre- or postoperative MRI findings and cerebellar sequelae in patients with medulloblastomas.", "content": "Correlation between pre- or postoperative MRI findings and cerebellar sequelae in patients with medulloblastomas. Immediate and delayed cerebellar dysfunction may be expected after surgical resection of a medulloblastoma. We investigated whether pre-operative and delayed post-operative MRI may correlate with such sequelae. The data of 31 patients in continuous complete remission after removal of medulloblastoma, irradiation and chemotherapy, were retrospectively reviewed. Magnetic Resonance Imaging (MRI) was analyzed for the following items: preoperative MRI (ratio of the surface of the tumor/posterior fossa, presence of ventricular dilatation or tonsilar hernia, involvement of the dentate nucleus) and delayed post-operative MRI (amount of cerebellar parenchyma removed, degree of cerebellar atrophy, presence of T1 hypointense regions in remaining cerebellar area and removal of region containing dentate nucleus). These data were correlated with immediate and long-term cerebellar syndrome and daily life repercussions. On preoperative MRI, the ratio of the surface of the tumor/posterior fossa and the presence of tonsilar hernia were significantly correlated with long-term sequelae on speech (respectively P = 0.027 and P = 0.05). Initial supratentorial ventricular dilatation was correlated with ability to sustain adequately daily tasks (P = 0.002). On delayed MRI, cerebellar atrophy was inversely correlated with ability to sustain daily tasks (P = 0.002). Hypointense T1 territory in remaining cerebellar parenchyma significantly correlated with immediate post-operative cerebellar syndrome (P = 0.01) and showed a tendency for post-operative mutism (P = 0.087) but was not correlated with any long-term sequelae. Increased cranial pressure on initial MRI and cerebellar atrophy detected on subsequent MRI studies correlated with immediate and long-term cerebellar sequelae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981689"}
{"pmid": "20981688", "title": "KIR receptor-ligand incompatibility predicts killing of osteosarcoma cell lines by allogeneic NK cells.", "content": "KIR receptor-ligand incompatibility predicts killing of osteosarcoma cell lines by allogeneic NK cells. The effectiveness of killer immunoglobulin-like receptor (KIR) incompatible, alloreactive natural killer (NK) cells has been primarily documented in hematological malignancies following stem-cell transplant. This effect has not been thoroughly evaluated for pediatric solid tumors. In this study, we evaluated KIR receptor-ligand incompatibility of NK cells against osteosarcoma cell lines. Following the KIR receptor-ligand mismatch model, MHC I cell surface expression and KIR ligand mRNA content of 3 osteosarcoma cell lines was determined by flow cytometry and quantitative reverse transcription-polymerase chain reaction (qRT-PCR), respectively. NK cells were isolated from healthy volunteer donor peripheral blood mononuclear cells (PBMCs) and KIR surface expression determined by flow cytometry. An Annexin-V based flow cytometric killing assay was used to determine % of dying osteosarcoma target cells by donor NK effector cells. One of seven healthy volunteer donors tested lacked phenotypic expression of one KIR. However, variable expression of KIR ligands was observed in 3 osteosarcoma cell lines. The highest rates of dying cells were seen in osteosarcoma cells with the lowest KIR ligand expression. Following down-regulation of KIR ligand expression, an increased susceptibility to NK cell-mediated killing was observed in a previously NK-resistant osteosarcoma cell line. Variable MHC I and KIR ligand expression was observed in osteosarcoma cell lines and this resulted in variable susceptibility to NK cell-mediated killing predicted by the degree of KIR receptor-ligand incompatibility. Collectively, these data provide rationale for the study of KIR incompatible stem-cell transplant for osteosarcoma, although further studies with fresh osteosarcoma samples are necessary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981688"}
{"pmid": "20981690", "title": "Safety and efficacy of high dose intravenous desferrioxamine for reduction of iron overload in sickle cell disease.", "content": "Safety and efficacy of high dose intravenous desferrioxamine for reduction of iron overload in sickle cell disease. Patients with sickle cell disease (SCD) receiving chronic blood transfusions are at risk of developing iron overload and organ toxicity. Chelation therapy with either subcutaneous (SQ) desferrioxamine (DFO) or oral deferasirox is effective in preventing and reducing iron overload but poses significant challenges with patient compliance. Intravenous (IV) infusions of high dose DFO have been utilized in non-compliant patients with heavy iron overload in small case series. We review our experience of high dose IV DFO in 27 patients with SCD who had significant iron overload and were noncompliant with subcutaneous (SQ) DFO. All patients were treated in-hospital with DFO 15 mg/kg/hr IV for 48 hr every 2-4 weeks with a mean duration of 19.6 months. We observed a significant decrease in liver iron burden with high dose intermittent IV DFO. Histological examination of liver biopsies revealed a decrease in the grade of liver iron storage. Also there was significant improvement in liver enzymes (ALT, AST) after high dose IV DFO. No audiologic or ophthalmologic toxicity or acute or chronic pulmonary complications were observed. In our cohort of patients with SCD we observed a significant decrease in liver iron burden with high dose IV DFO. Our patients tolerated the therapy well without any major toxicity. This regimen is safe and may be an option for poorly compliant patients with significant iron overload.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981690"}
{"pmid": "20981692", "title": "Child-related determinants of health-related quality of life in children with brain tumours 1 year after diagnosis.", "content": "Child-related determinants of health-related quality of life in children with brain tumours 1 year after diagnosis. Infratentorial tumour site and health-related quality of life (HRQL) 1 month after diagnosis have been shown to predict HRQL 1 year after diagnosis in children with brain tumours. This study aimed to identify additional early child-related determinants of parent- and child-report HRQL. Longitudinal prospective study. Semi-structured interviews took place approximately 1 and 12 months after diagnosis. HRQL was measured using the self- and parent-report Pediatric Quality of Life Scales (PedsQL 4.0) Total Scale Score and Health Utilities Index Mark 3 (HUI3) multi-attribute utility function. Child variables included performance and verbal IQ, general memory, selective attention executive function, behaviour problems, adaptive behaviour, symptoms of depression and anxiety and event related anxiety. Univariate analyses were used to identify potential early predictors of HRQL. Regression analysis was then used to identify the most important determinants of HRQL at 1 year. Thirty-five patients completed the 12-month interviews. Multivariate analysis showed infratentorial tumour site remained an important determinant of HRQL 1 year after diagnosis. Infratentorial tumour site and selective attention at 1 month generally best predicted poor self- and parent-report HRQL at 12 months. Adaptive behaviour and performance IQ may be important. Selective attention and infratentorial tumour site are most important in predicting both parent- and self-report HRQL at 1 year after diagnosis. Larger prospective studies are needed to confirm these findings. Cognitive remediation or/and pharmacological intervention, particularly aimed at children with infratentorial tumours may improve attention and subsequently HRQL and both merit further investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981692"}
{"pmid": "20981691", "title": "Nutritional intake of long-term survivors of childhood acute lymphoblastic leukemia: evidence for bone health interventional opportunities.", "content": "Nutritional intake of long-term survivors of childhood acute lymphoblastic leukemia: evidence for bone health interventional opportunities. Survivors of childhood acute lymphoblastic leukemia (ALL) are vulnerable to exaggeration of the aging process including decreased bone mineral density (BMD). As little is known about their dietary or nutrient intake that may affect their long-term bone health, we examined nutrient intake in long-term survivors of childhood ALL. Survivors (n = 164) of childhood ALL who had completed treatment for at least 5 years and were in continuous remission, completed a 110-item food questionnaire that reflected dietary intake over the previous year. The analyzed cohort comprised 34 females and 38 males younger than 19 years and 45 females and 47 males at least 19 years. Reported nutrient intake and food selection were compared with age-specific Recommended Dietary Allowance and USDA Pyramid Food Guide. Body mass index was compared to the general US population, adjusted for age, gender, Tanner stage and race. Less than 30% of participants met recommended dietary intakes for vitamin D, calcium, potassium, or magnesium regardless of age. Mean daily caloric intake was 2,204 kcal (51% from carbohydrates) for younger and 2,160 kcal (49% from carbohydrates) for older participants. Energy intake from sweets was 70% higher than recommended. Participants < 19 years were less likely to have a healthy weight (odds ratio 0.48, 95% CI 0.30-0.79); > 19 years more likely to be overweight (odds ratio 1.95, 95% CI 1.11-3.32, P < 0.002). Survivors of childhood ALL need careful dietary intervention to optimize long-term health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981691"}
{"pmid": "20981693", "title": "Outcome of Chinese children with unrelated donor hematopoietic stem cell transplantation.", "content": "Outcome of Chinese children with unrelated donor hematopoietic stem cell transplantation. To evaluate the prognostic factors and outcomes in Chinese children undergoing unrelated donor hematopoietic stem cell transplantation (UDT). Retrospective analysis of clinical data from 53 consecutive children who received UDT from November 2002 to December 2007 in our center. The median recipient age was 8.4 years (range 1.5-21). With a median follow-up of 36 months (range 18-80), the probability of 3-year overall survival (OS) was 71.5%. Treatment-related mortality (TRM) was 19.0%, and 9.5% died after post-transplant leukemia relapse. Incidence of grades I-II, III-IV acute and chronic graft versus host disease (GVHD) was 63%, 29%, and 46%. There was significant difference in OS between patients older or younger than 10 years (50.0% vs. 84.8%, P = 0.003), patients with different underlying diseases (ALL, AML, CML, and non-malignant disease: 36.4%, 80.0%, 61.5%, and 100%, P = 0.001) and patients receiving either HLA 0-1 versus 2-3 loci high-resolution mismatched UDT (83.3% vs. 53.3%, P = 0.034). The OS was not affected by the stem cell source (peripheral stem cell 70.3%, bone marrow 87.5% vs. cord blood 62.5%, P = 0.542) or the severity of acute GVHD (grade 0-II 77.8% vs. grade III-IV 60.0%, P = 0.140). The important prognostic factors for OS after UDT were the degree of HLA match, the age of patient and the type of underlying disease. Patients < 10-year with non-malignant disease receiving 0-1 locus high-resolution mismatched UDT had the most favorable outcomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981693"}
{"pmid": "20981694", "title": "Hemostatic management of an infant with severe hemophilia A and tetralogy of Fallot for cardiac bypass surgery.", "content": "Hemostatic management of an infant with severe hemophilia A and tetralogy of Fallot for cardiac bypass surgery. We present the hemostatic management of severe hemophilia A of an infant with high risk of inhibitor development who underwent cardiac surgery for correction of tetralogy of Fallot. Continuous infusion of recombinant factor VIII resulted in good hemostasis during surgery and postoperatively. Unfortunately, the patient had inhibitor development 2 months after cardiothoracic surgery. Although cardiac surgery is successful, exposure to factor concentrates in severe hemophilia early in life might predispose a patient to inhibitor development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981694"}
{"pmid": "20981695", "title": "Bilateral conjunctival extranodal marginal zone B-cell lymphoma.", "content": "Bilateral conjunctival extranodal marginal zone B-cell lymphoma. Extranodal marginal zone B-cell lymphomas (EMZLs), while relatively common in adults, are rare entities in the pediatric population. A subclass of the typically aggressive non-Hodgkin lymphomas, the few reported pediatric cases indicate that, as in adults, these tumors tend to be indolent. We present a case of EMZL arising in the conjunctivae in a 9-year-old male with bilateral disease. The patient was treated with surgical excision alone and has remained disease-free 6 years after the operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981695"}
{"pmid": "20981696", "title": "Familial pleuropulmonary blastoma in Australia.", "content": "Familial pleuropulmonary blastoma in Australia. We present three cases of pleuropulmonary blastoma (PPB) in Australian children. Each had a family history of childhood tumors which collectively included PPB, infant lung cyst, cystic nephroma, medullo-epithelioma and a Sertoli-Leydig ovarian tumor. Two of the patients also had additional malignancies: a concurrent bladder rhabdomyosarcoma and a post therapy non-PPB malignant lung tumor. In two cases, the family histories were elicited years after the PPB diagnosis. Archived pathology material allowed revision of pathologic diagnoses from decades earlier. These cases illustrate the importance of detailed inquiry into family medical history and the pleiotropy of the PPB-related familial cancer predisposition syndrome, which appears to result from heterozygous DICER1 mutations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981696"}
{"pmid": "20981698", "title": "Immunoglobulin anti-D for treatment of chronic ITP in children.", "content": "Immunoglobulin anti-D for treatment of chronic ITP in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981698"}
{"pmid": "20981697", "title": "Response of infantile hepatic hemangioma to propranolol resistant to high-dose methylprednisolone and interferon-α therapy.", "content": "Response of infantile hepatic hemangioma to propranolol resistant to high-dose methylprednisolone and interferon-α therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981697"}
{"pmid": "20981699", "title": "Novel mutation causing Hermansky-Pudlak Syndrome Type 2.", "content": "Novel mutation causing Hermansky-Pudlak Syndrome Type 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981699"}
{"pmid": "20981700", "title": "Low-dose carboxypeptidase-G2 for methotrexate toxicity in a child.", "content": "Low-dose carboxypeptidase-G2 for methotrexate toxicity in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981700"}
{"pmid": "20981709", "title": "Imaging near metal with a MAVRIC-SEMAC hybrid.", "content": "Imaging near metal with a MAVRIC-SEMAC hybrid. The recently developed multi-acquisition with variable resonance image combination (MAVRIC) and slice-encoding metal artifact correction (SEMAC) techniques can significantly reduce image artifacts commonly encountered near embedded metal hardware. These artifact reductions are enabled by applying alternative spectral and spatial-encoding schemes to conventional spin-echo imaging techniques. Here, the MAVRIC and SEMAC concepts are connected and discussed. The development of a hybrid technique that utilizes strengths of both methods is then introduced. The presented technique is shown capable of producing minimal artifact, high-resolution images near total joint replacements in a clinical setting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981709"}
{"pmid": "20981716", "title": "Algal biorefinery-based industry: an approach to address fuel and food insecurity for a carbon-smart world.", "content": "Algal biorefinery-based industry: an approach to address fuel and food insecurity for a carbon-smart world. Food and fuel production are intricately interconnected. In a carbon-smart society, it is imperative to produce both food and fuel sustainably. Integration of the emerging biorefinery concept with other industries can bring many environmental deliverables while mitigating several sustainability-related issues with respect to greenhouse gas emissions, fossil fuel usage, land use change for fuel production and future food insufficiency. A new biorefinery-based integrated industrial ecology encompasses the different value chain of products, coproducts, and services from the biorefinery industries. This paper discusses a framework to integrate the algal biofuel-based biorefinery, a booming biofuel sector, with other industries such as livestock, lignocellulosic and aquaculture. Using the USA as an example, this paper also illustrates the benefits associated with sustainable production of fuel and food. Policy and regulatory initiatives for synergistic development of the algal biofuel sector with other industries can bring many sustainable solutions for the future existence of mankind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981716"}
{"pmid": "20981710", "title": "The group II chaperonin Mm-Cpn binds and refolds human γD crystallin.", "content": "The group II chaperonin Mm-Cpn binds and refolds human γD crystallin. Chaperonins assist in the folding of nascent and misfolded proteins, though the mechanism of folding within the lumen of the chaperonin remains poorly understood. The archeal chaperonin from Methanococcus marapaludis, Mm-Cpn, shares the eightfold double barrel structure with other group II chaperonins, including the eukaryotic TRiC/CCT, required for actin and tubulin folding. However, Mm-Cpn is composed of a single species subunit, similar to group I chaperonin GroEL, rather than the eight subunit species needed for TRiC/CCT. Features of the β-sheet fold have been identified as sites of recognition by group II chaperonins. The crystallins, the major components of the vertebrate eye lens, are β-sheet proteins with two homologous Greek key domains. During refolding in vitro a partially folded intermediate is populated, and partitions between productive folding and off-pathway aggregation. We report here that in the presence of physiological concentrations of ATP, Mm-Cpn suppressed the aggregation of HγD-Crys by binding the partially folded intermediate. The complex was sufficiently stable to permit recovery by size exclusion chromatography. In the presence of ATP, Mm-Cpn promoted the refolding of the HγD-Crys intermediates to the native state. The ability of Mm-Cpn to bind and refold a human β-sheet protein suggests that Mm-Cpn may be useful as a simplified model for the substrate recognition mechanism of TRiC/CCT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981710"}
{"pmid": "20981718", "title": "Basic European ultrasound training in obstetrics and gynecology: where are we and where do we go from here?", "content": "Basic European ultrasound training in obstetrics and gynecology: where are we and where do we go from here?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981718"}
{"pmid": "20981719", "title": "Three-dimensional power Doppler: validity and reliability.", "content": "Three-dimensional power Doppler: validity and reliability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981719"}
{"pmid": "20981720", "title": "Evaluation of the cardiovascular system in twin-twin transfusion syndrome: it's not about 'scores' but about 'goals'.", "content": "Evaluation of the cardiovascular system in twin-twin transfusion syndrome: it's not about 'scores' but about 'goals'.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981720"}
{"pmid": "20981721", "title": "Re: Gestational sac volume: comparison between SonoAVC and VOCAL measurements at 11 + 0 to 13 + 6 weeks of gestation.", "content": "Re: Gestational sac volume: comparison between SonoAVC and VOCAL measurements at 11 + 0 to 13 + 6 weeks of gestation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981721"}
{"pmid": "20981723", "title": "Prenatal ultrasound findings of fetal urethral duplication.", "content": "Prenatal ultrasound findings of fetal urethral duplication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981723"}
{"pmid": "20981726", "title": "Lepidopteran larva consumption of soybean foliage: basis for developing multiple-species economic thresholds for pest management decisions.", "content": "Lepidopteran larva consumption of soybean foliage: basis for developing multiple-species economic thresholds for pest management decisions. Defoliation by Anticarsia gemmatalis (Hübner), Pseudoplusia includens (Walker), Spodoptera eridania (Cramer), S. cosmioides (Walker) and S. frugiperda (JE Smith) (Lepidoptera: Noctuidae) was evaluated in four soybean genotypes. A multiple-species economic threshold (ET), based upon the species' feeding capacity, is proposed with the aim of improving growers' management decisions on when to initiate control measures for the species complex. Consumption by A. gemmatalis, S. cosmioides or S. eridania on different genotypes was similar. The highest consumption of P. includens was 92.7 cm(2) on Codetec 219RR; that of S. frugiperda was 118 cm(2) on Codetec 219RR and 115.1 cm(2) on MSoy 8787RR. The insect injury equivalent for S. cosmoides, calculated on the basis of insect consumption, was double the standard consumption by A. gemmatalis, and statistically different from the other species tested, which were similar to each other. As S. cosmioides always defoliated nearly twice the leaf area of the other species, the injury equivalent would be 2 for this lepidopteran species and 1 for the other species. The recommended multiple-species ET to trigger the beginning of insect control would then be 20 insect equivalents per linear metre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981726"}
{"pmid": "20981727", "title": "High-throughput approach to detection of knockdown resistance (kdr) mutation in mosquitoes, Culex quinquefasciatus, based on real-time PCR using single-labelled hybridisation probe/melting curve analysis.", "content": "High-throughput approach to detection of knockdown resistance (kdr) mutation in mosquitoes, Culex quinquefasciatus, based on real-time PCR using single-labelled hybridisation probe/melting curve analysis. Knockdown resistance (kdr) mutation (L1014F) is a well-defined mechanism of resistance to pyrethroids and DDT in many insect species. Sensitive detection of the mutations associated with resistance is a prerequisite for resistance management strategies. The authors have developed a new real-time molecular diagnostic assay based on SimpleProbe(®)/melting curve analysis for large-scale kdr genotyping in the wild population of Culex quinquefasciatus Say, the principal vector of bancroftian filariasis. Melting curve analysis is based on the thermal stability difference between matched and mismatched DNA duplexes. The application of SimpleProbe(®) chemistry in insects described here is novel in entomology research. The mosquitoes homozygous for knockdown-resistant and knockdown-susceptible allele showed melting peaks at 60.45 °C (±0.25) and 64.09 °C (±0.24) respectively. The heterozygous mosquitoes yielded both peaks at approximately 60.5 °C (±0.2) and 64.20 °C (±0.23). Among the 92 samples genotyped, 16 were found to be homozygous resistant, 44 homozygous susceptible and 32 heterozygous. Comparative assessments were made of all the reported methods for kdr genotyping. The present method is cheaper, faster, more reliable and versatile than other alternatives proposed in detecting correct kdr genotypes in mosquitoes. This is the first report using a single-labelled hybridisation probe to detect point mutations in insect populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981727"}
{"pmid": "20981728", "title": "Expression of δ-endotoxin Cry1EC from an inducible promoter confers insect protection in peanut (Arachis hypogaea L.) plants.", "content": "Expression of δ-endotoxin Cry1EC from an inducible promoter confers insect protection in peanut (Arachis hypogaea L.) plants. Spodoptera litura (F.) is a polyphagous foliage insect and a major pest on peanut (Arachis hypogaea L.). Constitutive expression of δ-endotoxin Cry1EC gives protection against S. litura, as reported earlier. In this study, insect bites and salicylic acid induced high-level expression of Cry1EC was achieved in peanut. In order to achieve this, the expression of pathogenesis responsive promoter PR-1a was enhanced by placing it downstream of the CaMV35S promoter in the pCAMBIA 1300 backbone. The resultant promoter CaMV35S(r)PR-1a expressed a high level of insecticidal δ-endotoxin Cry1EC. The Gus expression under the control of CaMV35S(r)PR-1a served as a convenient marker for evaluation of promoter response to different treatments. Transgenic events that showed a very low level of uninduced expression and no expression in seeds were selected. The Cry1EC expression in leaves increased nearly eightfold in the selected event, following induction by salicylic acid. Both the salicylic-acid-treated and the S. litura-bitten leaves showed the highest expression after 2 days. Leaves from salicylic-acid-induced transgenic plants caused 100% mortality of S. litura at all stages of larval development. The results suggest that high expression of inducible promoters provides a good strategy for the development of safer transgenic food and feed crops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981728"}
{"pmid": "20981729", "title": "Textural and biochemical changes during ripening of old-fashioned salted herrings.", "content": "Textural and biochemical changes during ripening of old-fashioned salted herrings. Understanding of the biochemical reactions taking place during ripening of salted herring is still rather limited. Therefore, salted herrings were traditionally produced and the impact of the brine composition was evaluated in relation to the development of the characteristic texture of salted herrings. The aim of this study was to measure the texture changes during ripening using two different methods and to correlate the texture changes with brine composition and with biochemical modifications at the molecular level. During ripening (up to 151 days), hardness was higher in salted herrings compared to raw herrings, irrespective of the brine composition. However, the increase in hardness of herring prepared with extra brine occurred later. After prolonged storage (371 days), hardness was found for both batches to decrease to the level of raw herring. The increase in hardness during the ripening period could be explained by free-radical-induced cross-linking of myosin and the formation of aggregates. In addition, degradation of these aggregates correlated with the decrease in hardness observed at 371 days. Texture changes during ripening of salted herrings can be explained by oxidative reactions inducing myosin cross-linking followed by subsequent degradation of these myosin aggregates. The brine composition might play a role in the development of herring texture but this need to be investigated in more details.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981729"}
{"pmid": "20981732", "title": "Composition and volatile profiles of commercial Argentinean blue cheeses.", "content": "Composition and volatile profiles of commercial Argentinean blue cheeses. A first approach was made to acquire knowledge of the global composition, proteolysis, lipolysis and volatile profile of Argentinean blue cheeses. A total of 20 samples belonging to six leading commercial brands were analysed. A comparison of the results with bibliographical data on other blue cheeses was performed and the variability among and within dairy plants was also evaluated. Values of global composition were intermediate in relation to those reported for mould-ripened cheeses. Levels of proteolysis and lipolysis were lower than those of other blue cheeses. Volatile compound profiles were characterised mainly by short-chain fatty acids, methyl ketones and secondary alcohols, as reported previously for blue cheeses. Wide-ranging values of physicochemical parameters, lipolysis and proteolysis levels as well as volatile compound areas of cheeses produced by each dairy plant were observed. Owing to this high variability in the chemistry and volatile profile of cheeses, principal component analysis of the data did not show groupings by commercial brands. On the whole, Argentinean blue cheeses were characterised both by gross intermediate composition values and by proteolysis and lipolysis levels lower than those of blue cheeses of different origins. A typical volatile compound profile of blue cheeses was observed. The high variability found within each commercial brand could reflect the lack of standardisation of the technological processes used in blue cheese manufacturing in Argentina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981732"}
{"pmid": "20981735", "title": "Hyperlipidemic versus healthy pancreases: a proteomic analysis using an animal model.", "content": "Hyperlipidemic versus healthy pancreases: a proteomic analysis using an animal model. Hyperlipidemia is associated with a variety of pancreatic diseases; however, the underlying pathophysiology and molecular mechanisms remain undefined. Here, we performed a comparative proteomic analysis of pancreatic tissue obtained from hyperlipidemic rats to identify proteins that may be involved in mediating hyperlipidemia-associated pancreatic injury. Rats were fed a high-fat diet to induce hyperlipidemia. Control rats were fed a diet with normal fat content. Pancreatic tissue samples were obtained after 6 or 12 weeks and comparative proteomic analysis, using gel electrophoresis and mass spectrometry, was conducted to identify proteins, the expression of which were altered in pancreases from hyperlipidemic compared with control rat pancreases. The expression levels of 3 of 13 proteins were significantly altered in pancreatic samples from hyperlipidemic rats. Alpha-amylase and arginase II were dysregulated by more than twofold. These modulations persisted in pancreatic tissue obtained from late-stage hyperlipidemic rats. The levels of alpha-amylase and arginase II were significantly altered in pancreases obtained from rats with hyperlipidemia. These enzymes may be putative biomarkers of hyperlipidemia-mediated pancreatic injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981735"}
{"pmid": "20981736", "title": "A model of cadmium accumulation in the liver and kidney of sheep derived from soil and dietary characteristics.", "content": "A model of cadmium accumulation in the liver and kidney of sheep derived from soil and dietary characteristics. Cadmium accumulates in sheep tissues and often approaches the legal limit for human consumption in kidneys. Previous models have focused on transfer from plants to sheep but have restricted value due to seasonal and species variation in plant cadmium concentration. We created a model for the accumulation of cadmium in sheep using empirical relationships previously derived for accumulation in sheep kidney and liver from feeds, together with equations for accumulation in feeds derived from soil characteristics. The combined model relates soil cadmium to liver and kidney concentrations. Sensitivity analysis demonstrated that the kidney accumulated cadmium faster than the liver and the greatest influence was the total cadmium concentration in the soil. The weight gain of the sheep and soil pH where the feed was grown had relatively minor influences on cadmium concentration in liver or kidney. A combined model of soil, plant and sheep kidney and liver characteristics enables concentrations of cadmium in sheep liver and kidney to be predicted from soil characteristics. This will enable the long-term risks of specific sites to be predicted with greater accuracy than if just plant cadmium concentrations were utilized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981736"}
{"pmid": "20981740", "title": "Olfactory and visual responses of the longlegged chafer Hoplia spectabilis Medvedev (Coleoptera: Scarabaeidae) in Qinghai Province, China.", "content": "Olfactory and visual responses of the longlegged chafer Hoplia spectabilis Medvedev (Coleoptera: Scarabaeidae) in Qinghai Province, China. Monitoring traps and control methods are needed for the long-legged chafer, Hoplia spectabilis Medvedev, which has recently reached outbreak numbers in pastureland of Qinghai Province, China. Field trapping experiments, using cross-pane funnel (barrier) traps, showed that H. spectabilis adults were not significantly attracted to branches of the host plant Dasiphora fructicosa (L.) Rydb. However, beetles were slightly attracted to similar host plant branches infested by conspecific beetles, possibly owing to weakly attractive volatiles, primarily (Z)-3-hexenyl acetate, released from beetle-damaged host leaves. This compound was weakly attractive when released from traps. However, H. spectabilis beetles showed strong visual responses to yellow- or white-painted trap panes, with weaker responses to blue, red or green panes, and least response to black panes. Black traps at 0.2-1.5 m above ground intercepted significantly more beetles than traps at 2.5 m. The mean flight height based on trap catches was 0.88 m (SD = 0.76), yielding an effective flight layer of 1.9 m. Flight response of beetles to colored barrier traps occurred between 10:00 and 18:00, and peaked between 12:00-14:00, when daily temperatures reached their maximum. Unbaited yellow or white cross-pane funnel traps are recommended for both monitoring and mass-trapping programs against this economically and ecologically important scarab beetle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981740"}
{"pmid": "20981742", "title": "Comparison of treatment and outcome information between a clinical trial and the National Cancer Data Repository.", "content": "Comparison of treatment and outcome information between a clinical trial and the National Cancer Data Repository. Clinical trials are important but many factors limit their success, including the costs of long-term follow-up and participants often not being representative of the general population. The National Cancer Data Repository (NCDR) contains data about patients with cancer in England that may help overcome some of these problems. This study compared treatment and outcome information between the Medical Research Council Conventional versus Laparoscopic-Assisted Surgery in Colorectal Cancer (CLASICC) trial and the NCDR. Participants in the CLASICC trial were identified in the NCDR, and management and outcome data were compared. Data on all surgically treated English patients with colorectal cancer were extracted from the NCDR and compared with those of CLASICC participants. Survival and treatment data for those in the CLASICC trial were available in the NCDR for 98·9 and 95·8 per cent of patients respectively. There was agreement in operation type for 86·1 per cent of patients but surgical approach coding was poor, with only 58·4 per cent of laparoscopic procedures coded in the NCDR. There was no significant difference in survival calculated from either data set. Surgical information was available in the NCDR for 19 of 20 trial participants with missing data. The trial population was younger (P < 0·001), of better socioeconomic status (P = 0·001) and with earlier disease (P < 0·001) than the general surgically treated colorectal cancer population. Rectal cancer survival was similar, but 5-year survival after treatment of colonic cancer was significantly better in the trial than in the national data: 57·1 (95 per cent confidence interval 51·5 to 62·3) versus 49·8 (49·3 to 50·2) per cent respectively. The National Cancer Data Repository demonstrates potential for informing clinical trials, but limitations prevent full intention-to-treat analyses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981742"}
{"pmid": "20981743", "title": "Vascular Endothelial Growth Factor A isoform mRNA expression in pediatric acute myeloid leukemia.", "content": "Vascular Endothelial Growth Factor A isoform mRNA expression in pediatric acute myeloid leukemia. In AML high VEGFA protein expression correlates with poor overall and relapse-free survival (OS/RFS). To date, the relevance of the various VEGFA isoforms is unclear. We determined VEGF121, VEGF145, VEGF148, VEGF165, VEGF183, and VEGF189 mRNA expression in pediatric AML samples and investigated the relation between VEGFA isoform expression and clinicopatholologic characteristics and outcome. A significant co-expression of VEGF121, VEGF165, VEGF183, and VEGF189 isoforms was apparent (mean rho = 0.716, P < 0.0001). This co-expression justifies measuring a single VEGFA isoform (e.g., 121, 165, 183, and 189) as representative expression of all VEGFA isoforms in future studies designed to determine the prognostic importance of VEGFA isoforms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981743"}
{"pmid": "20981745", "title": "A molecular rationale of shock absorption and self-healing in a biomimetic apatite-collagen composite under mechanical load.", "content": "A molecular rationale of shock absorption and self-healing in a biomimetic apatite-collagen composite under mechanical load.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981745"}
{"pmid": "20981744", "title": "The Cus efflux system removes toxic ions via a methionine shuttle.", "content": "The Cus efflux system removes toxic ions via a methionine shuttle. Gram-negative bacteria, such as Escherichia coli, frequently utilize tripartite efflux complexes in the resistance-nodulation-cell division (RND) family to expel diverse toxic compounds from the cell. These efflux systems span the entire cell envelope to mediate the phenomenon of bacterial multidrug resistance. The three parts of the efflux complexes are: (1) a membrane fusion protein (MFP) connecting (2) a substrate-binding inner membrane transporter to (3) an outer membrane-anchored channel in the periplasmic space. One such efflux system CusCBA is responsible for extruding biocidal Cu(I) and Ag(I) ions. We recently determined the crystal structures of both the inner membrane transporter CusA and MFP CusB of the CusCBA tripartite efflux system from E. coli. These are the first structures of the heavy-metal efflux (HME) subfamily of the RND efflux pumps. Here, we summarize the structural information of these two efflux proteins and present the accumulated evidence that this efflux system utilizes methionine residues to bind and export Cu(I)/Ag(I). Genetic and structural analyses suggest that the CusA pump is capable of picking up the metal ions from both the periplasm and cytoplasm. We propose a stepwise shuttle mechanism for this pump to extrude metal ions from the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981744"}
{"pmid": "20981746", "title": "Programmable modulation of co-monomer relative reactivities for living coordination polymerization through reversible chain transfer between \"tight\" and \"loose\" ion pairs.", "content": "Programmable modulation of co-monomer relative reactivities for living coordination polymerization through reversible chain transfer between \"tight\" and \"loose\" ion pairs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981746"}
{"pmid": "20981747", "title": "A fluorescence selection method for accurate large-gene synthesis.", "content": "A fluorescence selection method for accurate large-gene synthesis. The fundamental problem for low-cost gene synthesis is errors that occur during the synthetic process. To address this problem, we developed a practical method that exploits the fact that the predominant errors are deletions. In this method, a simple fluorescence-based readout was used to distinguish error-free synthetic DNA molecules. To do this, we constructed vectors that contained multiple cloning sites and GFP. In the vectors, the GFP gene is designed to be out-of-frame, but insertion of an in-framed synthetic DNA construct into the appropriate cloning site will lead to fluorescent cell colonies. We successfully used this method to synthesize five genes and improved the bp per error from 629 to 6552 by selecting green fluorescent colonies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981747"}
{"pmid": "20981749", "title": "Extracellular silica nanocoat confers thermotolerance on individual cells: a case study of material-based functionalization of living cells.", "content": "Extracellular silica nanocoat confers thermotolerance on individual cells: a case study of material-based functionalization of living cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981749"}
{"pmid": "20981750", "title": "Atmospheric chemistry of HCF2O(CF2CF2O)xCF2H (x=2-4): kinetics and mechanisms of the chlorine-atom-initiated oxidation.", "content": "Atmospheric chemistry of HCF2O(CF2CF2O)xCF2H (x=2-4): kinetics and mechanisms of the chlorine-atom-initiated oxidation. Smog chamber/FTIR techniques were used to measure k(Cl+HCF(2)O(CF(2)CF(2)O)(x)CF(2)H)=(5.3±1.5)×10(-17) cm(3) molecule(-1) s(-1) in 700 Torr of N(2)/O(2) diluent at 296±1 K. The Cl-initiated atmospheric oxidation of HCF(2)O(CF(2)CF(2)O)(x)CF(2)H, x=2,3 and 4, gave COF(2) in molar yields of (593±41)%, (758±71)% and (939±73)%, respectively, with no other observable carbon-containing products (i.e., essentially complete conversion of the hydrofluoropolyethers into COF(2)). Quantitative infrared spectra for HCF(2)O(CF(2)CF(2)O)(x)CF(2)H (x=2-4) were recorded and used to estimate the radiative efficiencies of the title compounds (1.07, 1.33, and 1.36 W m(-2) ppb(-1)). Global warming potentials (100 year time horizon) of 3870, 4730 and 5060 were estimated for HCF(2)O(CF(2)CF(2)O)(x)CF(2)H, x=2, 3 and 4, respectively. The results are discussed with respect to the atmospheric chemistry and environmental impact of hydrofluoropolyethers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981750"}
{"pmid": "20981748", "title": "Bacterial synthesis of a flavonoid deoxyaminosugar conjugate in Escherichia coli expressing a glycosyltransferase of Arabidopsis thaliana.", "content": "Bacterial synthesis of a flavonoid deoxyaminosugar conjugate in Escherichia coli expressing a glycosyltransferase of Arabidopsis thaliana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981748"}
{"pmid": "20981751", "title": "Structure of Mycobacterium tuberculosis thioredoxin in complex with quinol inhibitor PMX464.", "content": "Structure of Mycobacterium tuberculosis thioredoxin in complex with quinol inhibitor PMX464. Thioredoxin (Trx) plays a critical role in the regulation of cellular redox homeostasis. Many disease causing pathogens rely on the Trx redox system for survival in conditions of environmental stress. The Trx redox system has been implicated in the resistance of Mycobacterium tuberculosis (Mtb) to phagocytosis. Trx is able to reduce a variety of target substrates and reactive oxygen species (ROS) through the cyclization of its active site dithiol to the oxidized disulphide Cys37-Cys40. Here we report the crystal structure of the Mtb Trx C active site mutant C40S (MtbTrxCC40S) in isolation and in complex with the hydroxycyclohexadienone inhibitor PMX464. We observe PMX464 is covalently bound to the active site residue Cys37 through Michael addition of the cyclohexadienone ring and also forms noncovalent contacts which mimic the binding of natural Trx ligands. In comparison with the ligand free MtbTrxCC40S structure a conformational change occurs in the PMX464 complex involving movement of helix α2 and the active site loop. These changes are almost identical to those observed for helix α2 in human Trx ligand complexes. Whereas the ligand free structure forms a homodimer the inhibitor complex unexpectedly forms a different dimer with one PMX464 molecule bound at the interface. This 2:1 MtbTrxCC40S-PMX464 complex is also observed using mass spectrometry measurements. This structure provides an unexpected scaffold for the design of improved Trx inhibitors targeted at developing treatments for tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981751"}
{"pmid": "20981754", "title": "Influence of MT effects on T(2) quantification with 3D balanced steady-state free precession imaging.", "content": "Influence of MT effects on T(2) quantification with 3D balanced steady-state free precession imaging. Signal from balanced steady-state free precession is affected by magnetization transfer. To investigate the possible effects on derived T(2) values using variable nutation steady-state free precession, magnetization transfer-effects were modulated by varying the radiofrequency pulse duration only or in combination with variable pulse repetition time. Simulations reveal a clear magnetization transfer dependency of T(2) when decreasing radiofrequency pulse duration, reaching maximal deviation of 34.6% underestimation with rectangular pulses of 300 μs duration. The observed T(2) deviation evaluated in the frontal white matter and caudate nucleus shows a larger underestimation than expected by numerical simulations. However, this observed difference between simulation and measurement is also observed in an aqueous probe and can therefore not be attributed to magnetization transfer: it is an unexpected sensitivity of derived T(2) to radiofrequency pulse modulation. As expected, the limit of sufficiently long radiofrequency pulse duration to suppress magnetization transfer-related signal modulations allows for proper T(2) estimation with variable nutation steady-state free precession.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981754"}
{"pmid": "20981756", "title": "Phase-contrast hard X-ray microscopy using synchrotron radiation for the diagnosis of onychomycosis.", "content": "Phase-contrast hard X-ray microscopy using synchrotron radiation for the diagnosis of onychomycosis. Onychomycosis, or fungal infection of the nail, is a disease seen frequently in clinical settings. However, the rates of positive identification using potassium hydroxide preparations or fungal cultures are relatively low. Precise diagnosis is possible via histopathologic examination to monitor the existence of fungus and performance of a fungal culture for confirmation. Phase-contrast hard X-ray microscopy using synchrotron radiation provides 70-nm spatial resolution and enables imaging of minute internal cellular structures. This study confirms the feasibility of diagnosing onychomycosis using a phase-contrast hard X-ray microscope developed at 1B2 beam line using a Pohang light source.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981756"}
{"pmid": "20981757", "title": "Background determination-based detection of scattered peaks.", "content": "Background determination-based detection of scattered peaks. In many instances of signal and image processing, it is indispensable to precisely distinguish scattered peaks from a background, e.g., camera signals in microscopy. Here we addressed the detection of Gaussian signals in simulated line profiles (LP) comparable with e.g., fluorescence microscopy data. In a first step, we measured the applicability of histogram-based global background estimation. We find that the method is valid for typical scattered Gaussian signals if they are averagely separated by interpeak distances of 5.5 standard deviations. This enabled us to design global background determination-based peak detection (GBPD). GBPD was compared with two local background determination-based signal detection methods that had been designed for analysis of electrophysiological data and microscopy images, respectively. We were able to prove via receiver-operator characteristic (ROC) comparisons of signal-to-noise ratio (SNR), interpeak distance, and filtering behavior that, when applicable, GBPD brings advantages in knowledge needed a priori, performance at any SNR, controllability and spatial resolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981757"}
{"pmid": "20981758", "title": "A comparison of imaging methodologies for 3D tissue engineering.", "content": "A comparison of imaging methodologies for 3D tissue engineering. Imaging of cells in two dimensions is routinely performed within cell biology and tissue engineering laboratories. When biology moves into three dimensions imaging becomes more challenging, especially when multiple cell types are used. This review compares imaging techniques used regularly in our laboratory in the culture of cells in both two and three dimensions. The techniques reviewed include phase contrast microscopy, fluorescent microscopy, confocal laser scanning microscopy, electron microscopy, and optical coherence tomography. We compare these techniques to the current \"gold standard\" for imaging three-dimensional tissue engineered constructs, histology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981758"}
{"pmid": "20981759", "title": "Elemental composition of Physarum compressum Alb. et Schw. sporocarps and their structures cultivated on rabbit dung and agar substrates.", "content": "Elemental composition of Physarum compressum Alb. et Schw. sporocarps and their structures cultivated on rabbit dung and agar substrates. The elemental composition of spores, peridium walls, and lime nodes of Physarum compressum sporocarps, cultivated on rabbit dung as a natural growing environment for the slime mold and on artificial agar medium, was compared to evaluate differences that may be dependent on substrates. Whole fruiting bodies and samples of both experimental media were extracted with nitric acid or Parr digest bomb, respectively, and analyzed by means of total X-ray reflection fluorescence (TXRF). Electron probe microanalysis (EPMA) of spores, peridium walls, and lime nodes structure was carried out with the scanning electron microscope equipped with energy-dispersive spectrometer. Because of minute sizes and roughness of investigated structures, Monte Carlo simulations were utilized to establish analytical conditions of EPMA. Biological and geological standards were used in the quantification of element concentrations. According to TXRF, the fruiting bodies from agar medium revealed lower concentrations of K, Ca, Cr, Mn, and Fe in relation to fruiting bodies from the dung, reflecting elemental relationships in the experimental media. According to EPMA, the highest Ca concentration was found in the lime nodes followed by the peridium and the spores. Culturing of the slime molds on the rabbit dung indicated higher concentration of Ca in the lime nodes and peridium walls when compared with those obtained from the sporocarps grown on agar media. The opposite relation was found for the spores. The concentration of Na, Mg, P, S, and Cl was generally lower in all structures of the sporocarps harvested from the dung than from the agar medium. K was in higher concentration in analyzed structures from dung than from agar. Different element uptake (except for Ca and K) was revealed by the two methods: TXRF and EPMA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981759"}
{"pmid": "20981760", "title": "Introduction: psychopharmacology.", "content": "Introduction: psychopharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981760"}
{"pmid": "20981761", "title": "Developmental pharmacology.", "content": "Developmental pharmacology. Understanding the pharmacokinetics and pharmacodynamics of drugs used in psychopharmacology across the pediatric age spectrum from infants to adolescents represents a major challenge for clinicians. In pediatrics, treatment protocols use either standard dose reductions for these drugs for children below a certain age or use less conventional parameters such as weight for allometric dosing. The rationale behind this, however, is often lacking. In this review current available data on the developmental changes in absorption, distribution, metabolism, and elimination of drugs are presented with a specific focus on metabolic pathways, indicating significant differences in the development of enzymes involved in the biotransformation of drugs used in psychopharmacology. Major emphasis will be given to the genetic variation in CYP2D6 activity, the most important enzyme for the metabolism of many psychotropic medications. Finally, this review will summarize the role of the developmental pharmacologist in ensuring rational use of drugs in children with developmental disabilities and in translating pharmacological concepts from the bench to the clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981761"}
{"pmid": "20981762", "title": "Treatment of epilepsy in children with developmental disabilities.", "content": "Treatment of epilepsy in children with developmental disabilities. Children with developmental disabilities are at increased risk for epilepsy with a prevalence rate higher than the general population. Some of the more common developmental disorders in childhood and the features of epilepsy in these conditions are discussed. Specifically, autism, cerebral palsy, mental retardation, and attention deficit and hyperactivity disorder are reviewed. Ideal treatment for developmentally-disabled children with epilepsy entails maximal seizure control without any significant adverse effects from the anti-epileptic drugs and good quality of life. Antiepileptic drugs' cognitive and behavioral adverse effects tend to occur more frequently in these children. Careful selection of the appropriate medication and close monitoring for drug adverse effects is important. The specific adverse effects of the older and newer antiepileptic drugs are also reviewed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981762"}
{"pmid": "20981763", "title": "Pain management in intellectually disabled children: Assessment, treatment, and translational research.", "content": "Pain management in intellectually disabled children: Assessment, treatment, and translational research. The primary focus of pain research in intellectually disabled individuals is still on pain assessment. Several observational pain assessment scales are available, each with its own characteristics, its own target group and its own validated use. Observational studies report differences in the treatment of intra- and postoperative pain of intellectually disabled children and almost all children with intellectual disability have comorbidities that need to be addressed. The scope of research has started to broaden. In this review we aim to answer the question: Can we integrate validated ways of pain assessment and postoperative pain treatment in intellectually disabled children to develop specific analgesic algorithms? Regrettably there is little knowledge on possible interaction effects and other relevant pharmacological issues. Possible genotype-phenotype associations related to pain in children with Down syndrome have several promises as six possible candidate genes are located on chromosome 21. In conclusion, the pain assessment tools for intellectually disabled children are there. We should now focus on tailoring the pain treatment. To this aim we need to perform pharmacokinetic and pharmacodynamic studies of analgesics and obtain information about the genotype-phenotype relationships for pain. This can lead to the development of specific analgesic algorithms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981763"}
{"pmid": "20981764", "title": "Managing irritability and aggression in autism spectrum disorders in children and adolescents.", "content": "Managing irritability and aggression in autism spectrum disorders in children and adolescents. Children with autism and autism spectrum disorders have a high rate of irritability and aggressive symptoms. In one study up to 20% of children with autism have symptoms of irritability and aggression including aggression, severe tantrums, and deliberate self injurious behavior (Lecavalier [2006] J. Autism Dev. Disord. 36:1101-1114.). These symptoms can lead to impairment and distress in both home and school settings. Medications to treat the irritability will be discussed across categories of antipsychotics, antidepressants, antihypertensive agents, and others. Emphasis will be placed on medications with the most safety and efficacy and FDA approval.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981764"}
{"pmid": "20981765", "title": "Pharmacotherapy of disruptive behavior in mentally retarded subjects: A review of the current literature.", "content": "Pharmacotherapy of disruptive behavior in mentally retarded subjects: A review of the current literature. The review presented here describes the state of the art of pharmacological treatment of aggression in subjects with mental retardation (MR) summing up results for both, children and adults. In general, psychopharmacological treatment of disruptive behavior in individuals with MR is similar to the treatment in subjects without MR. Compared to individuals without MR medication should \"start lower and go slower.\" For children and adults results were similar but were obtained by somewhat different medications. There is evidence for the conventional antipsychotic zuclopenthixol having positive effects on disruptive behavior. Most studies described the atypical antipsychotic risperidone to control severe self-injurious behavior and other behavior problems in a variety of diagnoses. Anticonvulsants, antidepressants, and anxiolytic medications are reported as effective as well for the treatment of individuals with disruptive behavior. Aggression-related behavior often gets treated with stimulants or with stimulants combined with atypical neuroleptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981765"}
{"pmid": "20981767", "title": "Introduction: Behavioral phenotypes in neurogenetic syndromes.", "content": "Introduction: Behavioral phenotypes in neurogenetic syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981767"}
{"pmid": "20981766", "title": "Review of pharmacotherapy options for the treatment of attention-deficit/hyperactivity disorder (ADHD) and ADHD-like symptoms in children and adolescents with developmental disorders.", "content": "Review of pharmacotherapy options for the treatment of attention-deficit/hyperactivity disorder (ADHD) and ADHD-like symptoms in children and adolescents with developmental disorders. Developmental disorders such as subaverage intelligence, pervasive developmental disorders, and genetic syndromes are frequently associated with comorbid attention-deficit/hyperactivity disorder (ADHD) or ADHD-like symptoms. While there are not pharmacological cures for these developmental disorders, coinciding ADHD and ADHD-like symptoms that contribute to difficulties in psychosocial functioning are frequently able to be addressed by pharmacotherapy. This article reviews what is known about the efficacy and tolerability of pharmacological interventions for the treatment of children and adolescents suffering from developmental disorders and comorbid ADHD/ADHD-like symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981766"}
{"pmid": "20981768", "title": "Advances in understanding behavioral phenotypes in neurogenetic syndromes.", "content": "Advances in understanding behavioral phenotypes in neurogenetic syndromes. Syndrome-specific behavior was proposed by Langdon Down in his first clinical descriptions. Research interest followed but waned during the eugenics era when antisocial behavior was attributed to people with intellectual disability (ID) and the US Supreme Court legalized involuntary sterilization. When these claims were refuted and behavioral treatments introduced, their focus on environmental determination minimized the importance of biological research. The modern era began with the recognition that patterned behavior, for example, self-injury in Lesch-Nyhan syndrome and hyperphagia in PWS, was syndrome-specific, and when parent support groups pointed out syndrome-specific behavioral similarities in their children. Syndrome-specific rating scales and methodologies followed to allow behavioral comparisons between syndromes. The focus initially was on specific behaviors but with refinements in neuropsychological tests has expanded to include neurocognitive profiles. Greater clarification in genetic diagnoses has led to mutant mouse behavioral models and neurophysiologic and neuroimaging strategies have made possible the study of brain circuits. There is growing interest in investigating the developmental trajectory of behaviors from infancy to adulthood and old age. Because anxiety, mood disturbance, repetitive behaviors, and social deficits commonly occur in people with severe ID, those affected are often given multiple psychiatric diagnoses. This has led to considerable confusion in the literature. It is critical to focus on specific behaviors and cognitive patterns in research and not confuse psychiatric symptoms that lack precise definitions and involve multiple genes, the so-called psychiatric phenotype, with the more specific behavioral phenotype. New treatments based on knowledge of underlying neurobiology call for more fine-grained definition of behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981768"}
{"pmid": "20981769", "title": "Mouse models of cognitive disabilities in trisomy 21 (Down syndrome).", "content": "Mouse models of cognitive disabilities in trisomy 21 (Down syndrome). Trisomy 21 (TRS21), also referred to as Down syndrome, occurs once in every 800-1,000 live births. It is the consequence of an extra copy of HSA21 that causes an imbalanced gene dose effect. TRS21 is the first known genetic cause of cognitive disability. The syndrome is complex, and includes various cardiac, immune, and bone disorders. Most of these signs are highly variable in expression but cognitive disability is the most constant characteristic of persons with TRS21. The syntenies that exist between HSA21 and three mouse chromosomes (MMU10, MMU16, and MMU17) offer the opportunity for a genotype-phenotype correlation. We present here the segmental trisomies available in the mouse and we discuss their contribution to the brain and cognitive phenotypes of TRS21.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981769"}
{"pmid": "20981770", "title": "Cognitive-behavioral features of Wolf-Hirschhorn syndrome and other subtelomeric microdeletions.", "content": "Cognitive-behavioral features of Wolf-Hirschhorn syndrome and other subtelomeric microdeletions. Wolf-Hirschhorn syndrome (WHS) is a complex congenital malformation produced by a loss of genomic material at the locus 4p16.3. In addition to its dysmorphic features, the deletion produces a range of intellectual disability (ID). Many clinical aspects of WHS are well-characterized; however, the cognitive-behavioral characteristics have been rarely examined in a systematic fashion. The purpose of our study was to examine the cognitive-behavioral features of WHS and to compare them to children with other subtelomeric deletions that also produce ID. We recruited 45 children with subtelomeric deletions and examined their cognitive-behavioral abilities using a neuropsychological assessment battery composed of standardized instruments. Nineteen children were diagnosed with WHS and 26 children with one of three other subtelomeric deletions-11q25 (Jacobsen syndrome), deletion 2q37, and inversion duplication deletion 8p21-23. We found children with WHS to be more severely impacted cognitively than children from any of the other groups. Their overall adaptive behavior was lower as well. However, children with WHS exhibit strengths in socialization skills comparable to the levels attained by the other groups we assessed. Importantly, the proportion of children with WHS with autism or autistic-like features is significantly lower than the rates of autism found in the other subtelomeric disorders we examined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981770"}
{"pmid": "20981771", "title": "The behavioral phenotype of Williams syndrome: A recognizable pattern of neurodevelopment.", "content": "The behavioral phenotype of Williams syndrome: A recognizable pattern of neurodevelopment. Williams syndrome (WS), caused by hemizygous deletion of 1.55-1.8 Mb of chromosome 7q11.23, has a recognizable behavior phenotype that is an important diagnostic sign. Individuals with WS are overly friendly, gregarious, empathetic, and loquacious, but have difficulty interpreting social cues and in making and keeping friends. The neurodevelopmental profile is characterized by overall intellectual disability, strength in concrete language, weakness in visuospatial construction, difficulties with sensory modulation, balance, and tool use, and problems with attention and anxiety. Structural and functional MRI studies demonstrate that gray matter deficiency in the intraparietal sulcus alters processing of spatial information in the dorsal stream (spatial) visual pathway, likely contributing to the visuospatial construction disability. Deficient regulation of the amygdala by the oribitofrontal cortex appears to underlie both the social disinhibition and the specific phobia common in WS. Continued study of cognition, behavior, neuroanatomy, and function in WS will continue to elucidate the neurogenetic underpinnings of human behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981771"}
{"pmid": "20981773", "title": "Neurobehavioral phenotype in Prader-Willi syndrome.", "content": "Neurobehavioral phenotype in Prader-Willi syndrome. The focus of this article is on the lifetime development of people with Prader-Willi syndrome (PWS) and specifically on the neurobehavioral phenotype. We consider studies of this aspect of the phenotype (the \"behavioral phenotype\" of the syndrome) that have confirmed that there are specific behaviors and psychiatric disorders, the propensities to which are increased in those with PWS, and cannot be accounted for by other variables such as IQ or adaptive behavior. Beginning with a description of what is observed in people with PWS, we review the evolving PWS phenotype and consider how some aspects of the phenotype might be best explained, and how this complex phenotype may relate to the equally complex genotype. We then consider in more detail some of the neurobehavioral aspects of the phenotype listed above that raise the greatest management problems for parents and carers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981773"}
{"pmid": "20981772", "title": "The behavioral phenotype of the Angelman syndrome.", "content": "The behavioral phenotype of the Angelman syndrome. The Angelman syndrome is clinically delineated by the combination of seizures, absent speech, hypermotoric and ataxic movements and certain remarkable behaviors. Those with the syndrome have a predisposition toward apparent happiness and paroxysms of laughter, and this finding helps distinguish Angelman syndrome from other ones involving severe developmental handicap. In this review the core neurological features of the syndrome are discussed with a focus on those behaviors that make Angelman syndrome a prototypical genetic disorder expressing a behavioral phenotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981772"}
{"pmid": "20981774", "title": "The behavioral phenotype of the idic(15) syndrome.", "content": "The behavioral phenotype of the idic(15) syndrome. Idic(15) syndrome is a neurogenetic disorder clinically delineated by early central hypotonia, developmental delay and intellectual disability (ID), epilepsy, absent or very poor speech, and autistic or autistic-like behavior. It is due to the presence of a supernumerary marker chromosome formed by the inverted duplication of proximal chromosome 15, resulting in tetrasomy 15p and partial tetrasomy 15q, and containing the Prader-Willi/Angelman syndrome critical region (PWS/ASCR). The vast majority of these idic(15) derives from the two homologous maternal chromosomes at meiosis. To better define the behavior profile, we studied 22 idic(15) children (15 males and 7 females) observed at our institute between 1986 and 2010, and present, in detail, case studies of five of them. We have been able to perform standardized and semi-standardized measures of intelligence, and psychopathology in only 13 of our 22 patients, due to the limitations of chronological age, and to the severity of ID (ranging from mild-moderate, in 15%, to severe-profound, in 85% of our sample). The results show a distinct developmental profile in idic(15) patients, that may provide a behavioral signature for autism spectrum disorder (ASD)/ASD-like arising from the susceptibility locus on proximal 15q; and suggest that idic(15) individuals are not \"true autistic,\" but distinct \"autistic-like\" persons with high score in the third ADOS-G and ADI-R area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981774"}
{"pmid": "20981775", "title": "Autism spectrum features in Smith-Magenis syndrome.", "content": "Autism spectrum features in Smith-Magenis syndrome. Smith-Magenis syndrome (SMS; OMIM 182290) is a neurodevelopmental disorder characterized by a well-defined pattern of anomalies. The majority of cases are due to a common deletion in chromosome 17p11.2 that includes the RAI1 gene. In children with SMS, autistic-like behaviors and symptoms start to emerge around 18 months of age. This study included 26 individuals (15 females and 11 males), with a confirmed deletion (del 17p11.2). Parents/caregivers were asked to complete the Social Responsiveness Scale (SRS) and the Social Communication Questionnaire (SCQ) both current and lifetime versions. The results suggest that 90% of the sample had SRS scores consistent with autism spectrum disorders. Moreover, females showed more impairment in total T-scores (P = 0.02), in the social cognition (P = 0.01) and autistic mannerisms (P = 0.002) subscales. The SCQ scores are consistent to show that a majority of individuals may meet criteria for autism spectrum disorders at some point in their lifetime. These results suggest that SMS needs to be considered in the differential diagnosis of autism spectrum disorders but also that therapeutic interventions for autism are likely to benefit individuals with SMS. The mechanisms by which the deletion of RAI1 and contiguous genes cause psychopathology remain unknown but they provide a solid starting point for further studies of gene-brain-behavior interactions in SMS and autism spectrum disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981775"}
{"pmid": "20981776", "title": "Pharmacological treatment of disruptive behavior in Smith-Magenis syndrome.", "content": "Pharmacological treatment of disruptive behavior in Smith-Magenis syndrome. Smith-Magenis syndrome (SMS) is a complex genetic syndrome caused by an interstitial deletion of chromosome 17p11.2. Children and adults with SMS appear to have unique neurobehavioral problems that include: sleep disturbance, self-injurious and maladaptive behaviors, stereotypies, and sensory integration disorders. We gathered retrospective psychotropic use information from parents or other caregivers of 62 individuals with SMS who were asked about use of psychotropic medication from a list of commonly used psychiatric medications. For those drugs identified, respondents were asked to rate the experience with the particular medication using a likert-type scale. Drugs were grouped into seven main categories: (1) stimulants; (2) antidepressants; (3) antipsychotics; (4) sleep aides; (5) mood stabilizers; (6) alpha 2 agonists; and (7) benzodiazepines. Relative frequencies, means and standard deviations pertaining to age and medication effect were derived for each medication category. Six of the seven medication categories examined showed no meaningful deviations from the \"no change\" score. The benzodiazepine group showed a mild detrimental effect. There were no gender differences in efficacy. Use of psychotropic medication started early in life (mean age 5 years), particularly with sleep aides. Although no medication category was identified as efficacious in SMS, all the categories reported herein may be considered as an option for brief symptomatic relief.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981776"}
{"pmid": "20981777", "title": "The behavioral phenotype of FMR1 mutations.", "content": "The behavioral phenotype of FMR1 mutations. The purpose of this article is to provide an overview of the behavioral phenotype of FMR1 mutations, including fragile X syndrome (FXS) in order to better understand the clinical involvement of individuals affected by mutations in this gene. FXS is associated with a wide range of intellectual and behavioral problems, some relatively mild and others quite severe. FXS is the most common cause of inherited intellectual disability and one of the most prevalent genetic causes of autism spectrum disorder. Learning difficulties, attentional problems, anxiety, aggressive behavior, stereotypies, and mood disorders are also frequent in FXS. Recent studies of children and adults have identified associations between FMR1 premutation and many of the same disorders. We examine the neurobehavioral phenotypes of FXS and FMR1 premutation as they manifest across the lifespan of the individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981777"}
{"pmid": "20981781", "title": "The anti-tumor effects of human immunodeficiency virus protease inhibitors: ready for real time?", "content": "The anti-tumor effects of human immunodeficiency virus protease inhibitors: ready for real time?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981781"}
{"pmid": "20981778", "title": "Behavioral features in young adults with FG syndrome (Opitz-Kaveggia syndrome).", "content": "Behavioral features in young adults with FG syndrome (Opitz-Kaveggia syndrome). Opitz and Kaveggia [Opitz and Kaveggia (1974); Z Kinderheilkd 117:1-18] reported on a family of five affected males with distinctive facial appearance, mental retardation, macrocephaly, imperforate anus, and hypotonia. Risheg et al. [Risheg et al. (2007); Nature Genetics 39:451-453] identified an identical mutation (p.R961W) in MED12 in six families with Opitz-Kaveggia syndrome, including a surviving affected man from the original family reported in 1974. The previously described behavior phenotype of hyperactivity, affability, and excessive talkativeness is very frequent in young boys with FG syndrome, along with socially oriented, attention-seeking behaviors. We present case studies of five adult males who were previously published with the clinical diagnosis of FG syndrome and then subsequently proven by Risheg et al. [Risheg et al. (2007); Nature Genetics 39:451-453] to have the recurrent p.R961W mutation. These individuals had episodic and longstanding behavior patterns, sometimes aggressive or self-abusing, that occurred more frequently in puberty and early adulthood. We try to describe the triggers for these behaviors, indicate how these behaviors change with advancing age, and suggest specific recommendations and interventional strategies based on the clinical histories of affected adolescent males with FG syndrome [Graham et al., 2008; Clark et al., 2009]. Young men who exhibit these behaviors may benefit from a careful examination to detect medical problems, use of mood stabilizers if needed, and/or behavioral intervention. The transition to a community living situation can be challenging without careful planning and timely behavioral intervention. They remain impulsive and can have aggressive outbursts when making the transition to adult life, but these challenges can be managed, as demonstrated by these clinical histories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981778"}
{"pmid": "20981782", "title": "Determination of three-dimensional ventricular strain distributions in gene-targeted mice using tagged MRI.", "content": "Determination of three-dimensional ventricular strain distributions in gene-targeted mice using tagged MRI. A model-based method for calculating three-dimensional (3D) cardiac wall strain distributions in the mouse has been developed and tested in a genetically engineered mouse model of dilated cardiomyopathy. Data from MR tagging and harmonic phase (HARP) tracking were used to measure material point displacements, and 3D Lagrangian strains were calculated throughout the entire left ventricle (LV) with a deformable parametric model. A mouse model where cardiomyocytes are specifically made deficient in vinculin (VclKO) were compared to wild-type (WT) littermates. 3D strain analysis revealed differences in LV wall mechanics between WT and VclKO mice at 8 weeks of age when systolic function had just begun to decline. Most notably, end-systolic radial strain and torsional shear were reduced in VclKO hearts which contributed to regional mechanical dysfunction. This study demonstrates the feasibility of using MRI tagging methods to detect alterations in 3D myocardial strain distributions in genetically engineered mouse models of cardiovascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981782"}
{"pmid": "20981784", "title": "2009 pandemic characteristics and controlling experiences of influenza H1N1 virus 1 year after the inception in Hangzhou, China.", "content": "2009 pandemic characteristics and controlling experiences of influenza H1N1 virus 1 year after the inception in Hangzhou, China. This paper described the epidemiology and controlling experiences of influenza H1N1 in Hangzhou in the past 1 year. A total of 2,078 cases confirmed by real-time quantitative PCR till March 31, 2010, were analyzed by SPSS 12.0 software. During the early pandemic stage, a patient must be tested for H1N1 nucleic acid once he/she had influenza-like symptoms with the epidemiological history in 7 days, and be diagnosed if it was positive. But in the pandemic peak, we made efforts to identify and save severe cases combined with pneumonia or hypoxemia or respiratory failure or septic shock or multiple organ dysfunctions and failure. In general, the prevalence was 2.77/100,000 (2,078/7,510,844); severity rate, 10.44% (217/2,078); fatality rate, 0.48% (10/2,078). The carrier and secondary attack rate were 9.52% (58/612) and 8.66% (53/612), respectively. About 50% of serious cases and 100% of deaths had the basic underlying diseases: cardiovascular diseases, 13.66% (25/217); chronic lung disease, 12.02% (22/217); pregnant, 7.1% (13/217). Of all cases aged from 1 month to 89 years, 52.99% (1,435/2,708) were in the 10-29 years, with most of them distributed in downtown area. The timeline showed two epidemic peaks occurred in September and November 2009, respectively. Furthermore, the hemagglutinin gene remained 99% identical with the American and vaccine strains, but only 70% with the 1947-2008 Chinese strains. In conclusion, Hangzhou pandemic influenza H1N1 was caused by the highly conserved virus, with low prevalence, transmission, and mortality, because we took efficient controlling methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981784"}
{"pmid": "20981786", "title": "Emergence, dominance, and possible decline of CXCR4 chemokine receptor usage during the course of HIV infection.", "content": "Emergence, dominance, and possible decline of CXCR4 chemokine receptor usage during the course of HIV infection. Binding to a chemokine receptor, either CCR5 or CXCR4, by the gp120 glycoprotein is an essential step in the pathway by which HIV enters host cells. Recently, CCR5 antagonists have been developed that obstruct binding of CCR5 by gp120, thus inhibiting host cell entry. Resistance to such CCR5 antagonists may emerge, however, through the selection of viral strains capable of utilizing CXCR4 receptors. This study explores the evolutionary context of emergence, and in many cases decline, of dominant CXCR4-usage (X4) during disease progression within a number of individuals. Of seven individuals exhibiting a switch to dominant CXCR4 usage, such dominance is transient in five of them with CCR5-usage (R5) re-emerging to dominate the viral population later in disease progression. Three individuals conform to documented X4 transience in that the re-emergence of R5 dominance is an outgrowth from the predominant R5 strain. However, in two individuals we observe a novel pathway for R5 re-emergence in that R5 strains emerge to dominate late in disease progression through continued evolution of the X4 population. This suggests that the molecular mechanism of such switches between R5 and X4-usage is strain specific and that no single mechanism is shared between individuals. These findings have implications for the understanding of the mechanisms of potential emergence of resistance to CCR5 antagonists through use of the CXCR4 receptor and support the importance to have an appropriately optimized background therapy for use with entry inhibitors and, as for all HAART, to monitor drug resistance in a comprehensive manner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981786"}
{"pmid": "20981788", "title": "Hepatitis B spliced protein (HBSP) generated by a spliced hepatitis B virus RNA participates in abnormality of fibrin formation and functions by binding to fibrinogen γ chain.", "content": "Hepatitis B spliced protein (HBSP) generated by a spliced hepatitis B virus RNA participates in abnormality of fibrin formation and functions by binding to fibrinogen γ chain. Hepatitis B spliced protein (HBSP) encoded by a 2.2 kb singly spliced hepatitis B virus (HBV) pre-genomic RNA (spliced between positions 2447 and 489 nt) is involved in the pathogenesis of HBV infection, whereas the exact mechanism is far from being fully elucidated. In this study, a yeast two-hybrid system using HBSP as bait was employed to screen binding partners for HBSP from a human liver cDNA library. The interaction between HBSP and fibrinogen γ chain (FGG) was further confirmed in vitro using a GST pull-down assay and confirmed in vivo using a mammalian two-hybrid assay and co-immunoprecipitation. It was identified that this interaction is mediated by the N terminal 47 amino acid residues of HBSP. HBSP could inhibit fibrin polymerization, factor XIIIa-mediated fibrin cross-linking, adhesion of platelets to fibrinogen and ADP-stimulated platelet aggregation. However, the interaction-mediating fragment 1-47 of HBSP is not sufficient for the inhibitory activity on fibrinogen function. The findings suggested that HBSP may participate in the hemostatic abnormality in patients with HBV-related liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981788"}
{"pmid": "20981787", "title": "Low prevalence of transmitted drug resistance among newly diagnosed HIV-1 patients in Latvia.", "content": "Low prevalence of transmitted drug resistance among newly diagnosed HIV-1 patients in Latvia. Transmitted drug resistance (TDR) is a concern because it may reduce the efficacy of antiretroviral treatment. Plasma samples of 119 HIV-1-infected patients who were newly diagnosed at the Infectology Center of Latvia in 2005 and 2006 were analyzed by an in-house genotypic resistance assay to determine the prevalence of TDR in Latvia. TDR was identified using the WHO 2009 list of mutations for surveillance of TDR as implemented in the Stanford Calibrated Population Resistance tool. Neighbor-joining phylogenetic analyses were used to determine genetic subtype and investigate the relatedness of the sequences. Resistance testing was successful in 117 of 119 patients. The study population represented ∼20% of all patients that were diagnosed in Latvia in 2005 and 2006 and was well distributed between gender, transmission routes, and areas of residence. Four patients showed evidence of TDR, which represents a prevalence of TDR of 3.4% (95% CI: 0.9-8.5%). All four patients displayed single, but different resistance mutations (M46I, F53L, M41L, and G190A). All patients, except one, were predicted to respond well to standard first-line therapy in Latvia. The prevalence of TDR in Latvia was low, which partly may be due to the low proportion of HIV-1 patients who receive antiretroviral therapy. The results indicate that routine resistance testing in Latvia currently should be focused on patients who display treatment failure, rather than treatment naive patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981787"}
{"pmid": "20981790", "title": "HCV in peripheral blood mononuclear cells are predominantly carried on the surface of cells in HIV/HCV co-infected individuals.", "content": "HCV in peripheral blood mononuclear cells are predominantly carried on the surface of cells in HIV/HCV co-infected individuals. HCV replication in extra-hepatic reservoirs has been suggested to occur in many tissues including PBMCs. A recent study showed evidence for compartmentalization and evolution of HCV in PBMCs. However, the cells that support HCV replication in PBMCs have not been identified. In this study we have fractionated the PBMC from HIV/HCV co-infected patients into T, monocytes, B and NK cells, and most of the HCV was located in CD3-cell fractions. Protease treatment of PBMCs to remove cell surface receptors resulted in the loss of HCV RNA suggesting that most of the HCV is present on the cell surface. PBMCs were treated by freeze-thaw nuclease method that would protect the HCV RNA in the virus but not the intracellular viral RNA. Data from this analysis support the conclusion that most of HCV is present on the cell surface. Even though the presence of minus strand RNA in PBMCs suggests that a low level HCV replication takes place within the PBMCs of HIV/HCV co-infected individuals, HCV in PBMC is present mainly on the surface of non-T cells, mostly on NK, monocytes and B cells. These results suggest a unique pathogenic role of NK, monocyte and B cells as carriers of HCV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981790"}
{"pmid": "20981785", "title": "Low rate of virological failure and maintenance of susceptibility to HIV-1 protease inhibitors with first-line lopinavir/ritonavir-based antiretroviral treatment in clinical practice.", "content": "Low rate of virological failure and maintenance of susceptibility to HIV-1 protease inhibitors with first-line lopinavir/ritonavir-based antiretroviral treatment in clinical practice. Protease inhibitor (PI)-resistant HIV-1 has hardly ever been detected at failed boosted PI-based first-line antiretroviral regimens in clinical trials. However, this phenomenon has not been investigated in clinical practice. To address this gap, data from patients starting a first-line lopinavir/ritonavir (LPV/rtv)-based therapy with available baseline HIV-1 RNA load, a viral genotype and follow-up viral load after 3 and 6 months of treatment were extracted from the Italian Antiretroviral Resistance Cohort Analysis (ARCA) observational database. Based on survival analysis, 39 (7.1%) and 43 (7.8%) of the 548 examined patient cases had an HIV-1 RNA >500 and >50 copies/ml, respectively, after 6 months of treatment. Cox proportional hazard models detected baseline HIV-1 RNA (RH 1.79, 95%CI 1.10-2.92 per 1-log(10) increase, P=0.02) and resistance to the nucleoside backbone (RH 1.04, 95%CI 1.02-1.06 per 10-point increase using the Stanford HIVdb algorithm, P<0.001) as independent predictors of HIV-1 RNA at >500 copies/ml, but not at the >50 copies/ml cutoff criteria. Higher baseline viral load, older patient age, heterosexual route of infection and use of tenofovir/emtricitabine were predictors of failure at month 3 using the 50-copy and/or 500-copy threshold. Resistance to LPV/rtv did not occur or increase in any of the available 36 follow-up HIV-1 genotypes. Resistance to the nucleoside backbone (M184V) developed in four cases. Despite the likely differences in patient population and adherence, both the low rate of virological failure and the lack of development of LPV/rtv resistance documented in clinical trials are thus confirmed in clinical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981785"}
{"pmid": "20981791", "title": "Molecular epidemiology of human astrovirus infections in Saudi Arabia pediatric patients.", "content": "Molecular epidemiology of human astrovirus infections in Saudi Arabia pediatric patients. Earlier work Tayeb et al. [Tayeb et al. (2008): J Med Virol 80: 1919-1929] set out to study the epidemiology of diarrhea viruses in pediatric populations. The study addressed initially rotavirus, enteric adenovirus, and astrovirus but was later expanded to include norovirus (NoV). Viruses were sought in fecal specimens and characterized for genotype using molecular methods (PCR, RT-PCR, and RFLP) for the first time in KSA. The survey focused on three locations; Jeddah, Makkah, and Riyadh. During the Hajj, the chief population fluxes are via Jeddah to Makkah. One thousand samples were obtained from children (aged 6 years or less) presenting with diarrhea and thus representing community acquired rather than nosocomial infections. Rotavirus was identified in 6% of the samples followed by NoV accounted for 3.5%, astrovirus 1.9%, and adenovirus 1.4%. Rotavirus G9 was characterized for the first time in Saudi Arabia. Adenoviruses were confirmed and further typed using hexon-specific PCR and RFLP. These data were published by Tayeb et al. [Tayeb et al. (2008): J Med Virol 80: 1919-1929]. However, the nature of astrovirus identified was not investigated further. Therefore, more analysis details are appropriate for astrovirus in the Kingdom. As an extension of earlier work carried out on astrovirus serotype distribution in the Kingdom [Tayeb et al. (2008): J Med Virol 80: 1919-1929], a major objective of the project is to use molecular methods to determine the distribution of astrovirus genotype. Such data will help to provide valuable insights into genetic identities and possible sources of virus strains involved not only in pediatric gastroenteritis but also possible outbreaks in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981791"}
{"pmid": "20981792", "title": "Cardioprotective effect of NO-metoprolol in murine coxsackievirus B3-induced myocarditis.", "content": "Cardioprotective effect of NO-metoprolol in murine coxsackievirus B3-induced myocarditis. The effect of NO-metoprolol, that is, 3-nitrooxypivaloyl metoprolol-amide, a novel NO-releasing derivative of the β1-blocking drug metoprolol was investigated in A.CA/SnJ mice infected with coxsackievirus B3 (CVB3) and compared to metoprolol and placebo. Daily treatment of mice with the respective drug started immediately (experiment A) or 3 days after virus infection (experiment B) and was continued until day 13 post-infection (p.i.). Two doses of NO-metoprolol were administered. Body mass differences, viral load, and histopathological signs of myocarditis were compared between the several groups. As a result, NO-metoprolol diminished significantly the body weight loss, the viral load and the histopathology, whereas metoprolol treatment led solely to a significant attenuation of myocardial damage. In experiment A, low dose NO-metoprolol decreased significantly enteroviral copy numbers. Both doses of NO-metoprolol had a significant effect on reduction of myocardial infiltrates and fibrosis. The data suggest that delayed drug administration might more advantageous. Both doses of NO-metoprolol reduced significantly the scores of four tested parameters compared to placebo. Body weight loss, virus titers, plus-strand as well as minus-strand enteroviral RNA levels, infiltration and fibrosis scores were diminished significantly when NO-metoprolol was given 3 days p.i. In addition, a significant difference regarding the enteroviral copy numbers was observed between low dose NO-metoprolol- and metoprolol-treated mice. Treatment with metoprolol reduced insignificantly the viral load and body weight loss (experiment A and B) but led to a significant reduction of myocardial histopathology in experiment A. The results indicate that NO-metoprolol treatment has a greater therapeutic benefit than metoprolol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981792"}
{"pmid": "20981789", "title": "Neutralizing antibodies to interferon-α and circulating interferon in patients with chronic hepatitis C non-responding to pegylated interferon plus ribavirin re-treated by pegylated interferon-α-2a and ribavirin (ANRS HC16 GAMMATRI substudy).", "content": "Neutralizing antibodies to interferon-α and circulating interferon in patients with chronic hepatitis C non-responding to pegylated interferon plus ribavirin re-treated by pegylated interferon-α-2a and ribavirin (ANRS HC16 GAMMATRI substudy). A lack of antiviral response in patients with chronic hepatitis C treated with pegylated (PEG)-interferon (IFN)-α-2a + ribavirin (RIBA) may be explained by neutralizing antibodies to IFN-α-2a. The aim of this study was to assess neutralizing antibodies to IFN-α-2a and IFN levels in non-responder patients who were re-treated by PEG IFN-α-2a and RIBA for 12 weeks. Non-responders to a first-line treatment of PEG IFN-α-2a + RIBA were included for treatment with PEG IFN-α-2a (180 µg/week) + RIBA (1,000 mg/day if <75 kg, 1,200 mg otherwise) for 48 weeks. HCV RNA was measured at week 12. IFN levels and neutralizing antibodies to IFN-α-2a were measured retrospectively on stored sera at baseline and weeks 4 and 12, using a quantitative sandwich ELISA for neutralizing antibodies to IFN-α-2a. Twenty-three patients were non-responders and 19 patients were responders at week 12 of the initial phase of the second-line treatment. Non-responders and responders did not differ statistically: baseline age (median age 47 vs. 50 years), HCV RNA (median 6.8 vs. 6.4 log(10) copies/ml), gender (70% vs. 73% males), genotype (genotype 1: 91% vs. 80%). The median IFN-α-2a levels (pg/ml) at weeks 0, 4, and 12 (interquartile range) did not differ between the 19 responders to initial phase of second-line treatment and the 23 non-responders: <3.3 (<3.3-371.4), 1457.3 (106.8-3284.8), and 1,652 (90.8-5,000); 84.5 (3.3-277.4), 1407.4 (120.2-2443.4), and 1620.1 (120.2-2287.1), respectively. Among non-selected consecutive non-responder patients, re-treatment with PEG IFN-α-2a + RIBA is associated with virological response regardless of the presence of antibody-mediated resistance to conventional IFN treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981789"}
{"pmid": "20981793", "title": "Development and evaluation of a fluorogenic real-time RT-PCR for the detection of dengue 3 virus.", "content": "Development and evaluation of a fluorogenic real-time RT-PCR for the detection of dengue 3 virus. A dengue-3-specific real-time reverse transcriptase-polymerase chain reaction (RT-PCR) was developed using the novel Light Upon eXtension (LUX™) fluorogenic technology. A labeled forward primer and a standard reverse primer that target a conserved region within the non-structural 1 (NS1) gene of dengue 3 strains were designed. The dengue-3-specific assay did not recognize other dengue serotypes and related flaviviruses. Using a tenfold serial dilution of plasmid DNA containing the dengue 3 NS1 gene as standards, the range of dengue virus detection was determined to be from 10(3) to 10(9) copies/ml or from 80 to 8 × 10(7) copies/reaction with an average correlation coefficient of ≥ 0.99. The mean intra-assay coefficient of variation (CV) at 2.01% and the mean inter-assay CV at 2.68% suggest the repeatability of the procedure. Moreover, the fluorogenic assay was evaluated by using clinical specimens and comparing test results with historical data obtained from conventional RT-PCR, which served as the criterion standard. Using patient sera as test samples, the assay demonstrated 95.45% sensitivity and 100% specificity, respectively. These results reveal that the real-time RT-PCR assay may be utilized as a rapid, convenient, and sensitive tool for the detection of dengue 3 in clinical and laboratory specimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981793"}
{"pmid": "20981795", "title": "Characterization of genotype G8 strains from Malawi, Kenya, and South Africa.", "content": "Characterization of genotype G8 strains from Malawi, Kenya, and South Africa. Reviews of the global distribution of rotavirus genotypes have revealed the continuous circulation of G8 strains in Africa, often responsible for more cases of rotavirus disease than the more common G1-G4 rotavirus strains. During the study, genotype G8 strains from Malawi, Kenya, and South Africa were detected and the VP7 and VP4 genes of selected specimens were sequenced. Results indicated that G8 strains appeared to reassort frequently and were associated with P[6], P[4], and P[8] specificity. Phylogenetic analysis suggested that G8 strains occurred in a North/South African phylogenetic divide. In addition, G8 strains appear to be able to infect non-human primates and strains with close phylogenetic relationships were detected in the same year on two continents. Any rotavirus vaccine introduced into African environments will need to demonstrate protective efficacy against unusual genotype combinations, new serotypes, and animal strains. Therefore, continuous monitoring of rotavirus strains in human and animal populations in Africa is a necessity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981795"}
{"pmid": "20981794", "title": "Reactivation of Epstein-Barr virus in B cells of patients with chronic hepatitis C.", "content": "Reactivation of Epstein-Barr virus in B cells of patients with chronic hepatitis C. Hepatitis C virus (HCV) infection is associated with lymphoproliferative disorders. HCV infection of B cells is a predictive factor for lymphoproliferative disorders in patients with chronic hepatitis C, although its molecular mechanisms remain unknown. Epstein-Barr virus (EBV) is a B cell-tropic virus with the potential to cause lymphoproliferative disorders, and its reactivation is induced by several viruses and cytokines. The possibility that HCV infection triggers reactivation of EBV and induces lymphoproliferative disorders were investigated. Expression of EBV mRNAs was analyzed by RT-PCR in patients infected with HCV and control subjects, and correlations between reactivation of EBV and markers for lymphoproliferative disorders were investigated. BZLF1 mRNA, a starter molecule of reactivation, was detected in peripheral blood mononuclear cells from 12 of 52 (23%), patients infected with HCV and the frequency was higher than in healthy subjects [3 of 43 (9%), P = 0.032]. But the presence of the BZLF1 mRNA was not associated with an abnormality of markers for lymphoproliferative disorders. This study on BZLF1 mRNA expression among lymphoid cell subsets showed that reactivation of EBV was observed specifically in B cells. The BZLF1 mRNA disappeared following anti-viral therapy and remained negative after eradication of HCV in patients with a sustained viral response, while the EBER1 RNA, a marker for persistence of EBV, was detected throughout the therapy. Infection with HCV induces reactivation of EBV in B cells, but this reactivation was not associated directly with lymphoproliferative disorders triggered by HCV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981794"}
{"pmid": "20981796", "title": "A Fas gene polymorphism influences herpes simplex virus type 2 infection in South African women.", "content": "A Fas gene polymorphism influences herpes simplex virus type 2 infection in South African women. Herpes simplex virus type 2 (HSV-2) is a common sexually transmitted infection (STI) worldwide that causes genital infection. Among several factors responsible, host genetic factors may play an important role in susceptibility to HSV-2 infection. Apoptosis is a vital mechanism in eliminating virus-infected cells and controlling viral infections. Apoptosis can be regulated and triggered by the interaction between Fas and Fas Ligand (FasL). Polymorphisms in genes encoding Fas and FasL might result in altered apoptosis and contribute in susceptibility to viral infections. Two polymorphisms in Fas gene (FasR-1377G > A, FasR-670A > G) and one in FasL gene (FasL-844T > C) have been well studied and associated with different diseases. These polymorphisms were investigated in 407 South African women of black African and mixed-ancestry origin to determine if they were associated with HSV-2 seropositivity. Two hundred sixty-five women were HSV-2 infected and 142 were non-infected. HSV-2 was detected using HerpeSelect ELISA test and genotyping was performed using TaqMan assay. FasR-1377A allele showed a statistically significant association (P = 0.008) with reduced risk of HSV-2 infection. Analyzing the FasR haplotypes also showed a statistically significant association (P = 0.0001) with FasR-1377/FasR-670 AG haplotype and reduced risk of HSV-2 infection. There was no significant association found with FasR-670A > G and FasL-844T > C polymorphisms and risk of HSV-2 infection. This is, to our knowledge, the first time a non-HLA genetic link with HSV-2 infection has been reported.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981796"}
{"pmid": "20981797", "title": "Infantile hypertrophic pyloric stenosis: are viruses involved?", "content": "Infantile hypertrophic pyloric stenosis: are viruses involved? Infantile hypertrophic pyloric stenosis (IHPS) is characterized by abnormal thickening of the internal circular muscle layer. IHPS is known to be due to a combination of genetic and environmental factors, but its precise causes and pathophysiology are poorly understood. The objective of the study is to determine the prevalence of the principal viruses targeting the respiratory and digestive tracts in children with IHPS. Nasopharyngeal fluids, stools, vomit, and surgical pyloric muscle fragments and swabs were tested by cell culture, viral antigen assay and PCR. IHPS was diagnosed in 23 boys and 8 girls with a mean (± SD) age of 42 ± 15 days (range 20-88 days). There was no seasonal pattern of diagnosis. Twenty-two children (71%) lost weight (mean 246 ± 164 g, range 30-600 g) after the onset of vomiting, and five (16.1%) were dehydrated. Seven (22.6%) infants had been exposed to an infectious contact within 15 days before admission, and one on the day of admission (3.2%). Ear, nose and throat samples and pyloric muscle specimens were negative for all the viruses tested. An adenovirus type 3 was recovered from one stool sample, and RT-PCR was positive for an enterovirus on one vomit sample. This study suggests that the principal viruses targeting the respiratory and digestive tracts are not responsible for IHPS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981797"}
{"pmid": "20981798", "title": "Longitudinal course of human metapneumovirus antibody titers and reinfection in healthy adults.", "content": "Longitudinal course of human metapneumovirus antibody titers and reinfection in healthy adults. The purpose of this study was to evaluate the frequency of human metapneumovirus (hMPV) infection in adults and to determine the association between the levels of serum antibody titers and the susceptibility to reinfection. Serum samples collected at the periodic occupational medical checkup for employees of a hospital were subjected to an ELISA test. Of the 289 subjects, 288 (99.7%) had hMPV antibody titers that were more than 1:100 in May 2006. The percentage of subjects with a titer of ≥ 3,200 was significantly higher in adults aged 40-65 years old (30.2-31.5%) compared to young adults 20-39 years old (13.6%) (P < 0.05). To investigate the longitudinal course of the hMPV antibody titer, a total of 649 serum samples collected from 59 subjects who had participated in all biannual medical checkups between 2001 and 2006 were tested. We found that ten serum pairs showed a greater than fourfold increase in hMPV antibody titers. Additionally, the 5-year reinfection rate was estimated at 16.9% (10 of 59 subjects). The baseline titer before the fourfold increase ranged from 1:100 to 1:3,200, and the titer returned to baseline levels 2 or 3 years after the fourfold increase. The antibody titer of the person with the baseline titer of 1:100 showed a greater than fourfold increase twice within a year. Sixty to 80% of adults had an ELISA titer of 1:800 to 1:1,600, suggesting that such an antibody titer is not enough to protect from hMPV infection and that reinfection could occur among adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981798"}
{"pmid": "20981800", "title": "Evaluation of an immunochromatography method for rapid detection of noroviruses in clinical specimens in Thailand.", "content": "Evaluation of an immunochromatography method for rapid detection of noroviruses in clinical specimens in Thailand. Norovirus (NoV) is a causative agent of gastroenteritis in children and adults worldwide. Although reverse transcription-polymerase chain reaction (RT-PCR) has been accepted as the standard method for diagnosis of NoV infection, it requires well-trained personnel and sophisticated equipments. Performance of a commercial immunochromatography (IC) test for rapid detection of NoV was evaluated with fecal specimens collected from children admitted to a hospital with acute gastroenteritis during 2005-2007 in Chiang Mai, Thailand. A total of 463 fecal specimens were tested for the presence of NoV by a commercial immunochromatography kit (IP-NoV) and by RT-PCR. Sensitivity, specificity, and agreement of immunochromatography as compared to RT-PCR were 74.2%, 99.5%, and 96.1%, respectively. Based on the NoV genotypes determined by phylogenetic analysis, immunochromatography detected NoV GII/3, GII/4, GII/6, GII/13, GII/15, and GII/16 genotypes. The findings indicate that the immunochromatography kit could be used for a direct detection of NoV GII in clinical specimens and covering a wide range of NoV genotypes circulating in Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981800"}
{"pmid": "20981801", "title": "Rhinovirus species and their clinical presentation among different risk groups of non-hospitalized patients.", "content": "Rhinovirus species and their clinical presentation among different risk groups of non-hospitalized patients. Infections caused by Human Rhinoviruses (HRVs) account for 25-50% of respiratory illnesses among individuals presenting influenza-like illness (ILI). HRVs could be classified in at least three species: HRV-A, HRV-B, and HRV-C. The HRV-C species has frequently been described among children and has led to severe illness resulting in hospitalization; however, the occurrence among adults is unknown. The aim of this study was to assess the clinical presentation and species distribution of HRV infections in different populations during 2001-2008. A total of 770 samples were collected. Subjects consisted of 136 adults from the general community and 207 health-care workers (2001-2003), 232 renal-transplanted outpatients (2002-2004), 70 children with congenital heart disease (2005) and 125 children from a day-care center (2008). Amplification of HRV genes was performed by reverse transcriptase-polymerase chain reaction (RT-PCR) and followed by sequencing and phylogenetic analysis. HRV was detected in 27.4% of samples (211/770), with 72 children (36.9%) and 139 adults infected (24.2%). A total of 89.61% (138/154) unknown HRV strains were sequenced, and 79.22% (122/138) were analyzed. We identified 74 isolates (60.7%) of the HRV A species, 21 (17.2%) of the HRV B species and 27 isolates (22.1%) of the HRV C species. HRV species A and B caused ILI among adult patients, whereas HRV-C did not. The dynamics of infection among different species deserve further analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981801"}
{"pmid": "20981802", "title": "Stable human T-cell lymphotropic virus type 1 (HTLV-1) subtype a/subgroup a endemicity in Amerindians from Northwest Argentina: a health problem to be resolved.", "content": "Stable human T-cell lymphotropic virus type 1 (HTLV-1) subtype a/subgroup a endemicity in Amerindians from Northwest Argentina: a health problem to be resolved. Jujuy province, in Northwest Argentina, is known to be endemic for HTLV-1 infection. Moreover, foci of HTLV-1 associated pathologies have also been described in this region. To gain an insight into the current situation of HTLV-1/2 in this endemic area, a seroprevalence and phylogenetic study was performed among a Kolla community from Abra Pampa city and surroundings. Out of 112 individuals, 11 (9.8%) were confirmed as HTLV-1 positive and no HTLV-2 infection was detected. The phylogenetic analysis of the LTR region showed that all the HTLV-1 sequences belonged to the Cosmopolitan subtype a/transcontinental subgroup A, and were closely related to reference sequences from Peru, Argentina, and the South of Brazil (P = 0.82). Considering the cultural and historical features of this community and in spite of the mandatory detection of anti-HTLV-1/2 antibodies in blood banks since 2005, it would be important to implement new public health measures focused on decreasing HTLV-1 transmission in this endemic area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981802"}
{"pmid": "20981803", "title": "Seroprevalence of varicella-zoster virus in Korea.", "content": "Seroprevalence of varicella-zoster virus in Korea. Varicella-zoster virus (VZV) causes chickenpox and herpes zoster. Korea is assumed to have a high seroprevalence of VZV, although data are scant. A cross-sectional and age-stratified study was conducted to investigate the seroprevalence of VZV in different ages in the South Korean population. Four medical institutions were chosen in the southwestern area of Seoul in the vicinity of Gyeonggi-do. Serum samples were obtained at each institution from consenting patients during April-August, 2008. Anti-VZV IgG antibody was measured by an enzyme immunoassay. Of the 887 patients, 87.6% had anti-VZV IgG antibody. The prevalence of anti-VZV IgG antibody was 75% during the first 3 months after birth, but was only 13.6% 12 months after birth. Anti-VZV IgG antibody prevalence increased, first at 1-2 years of age, and then at 5-6 years of age. The seroprevalence rate exceeded 90% in subjects over 11 years of age. The results show that the seroprevalence of VZV is relatively high in the South Korean population. A study on the rate of varicella vaccination and the vaccine's efficacy in South Korea is warranted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981803"}
{"pmid": "20981799", "title": "Molecular epidemiology of noroviruses detected in seasonal outbreaks of acute nonbacterial gastroenteritis in Osaka City, Japan, from 1996-1997 to 2008-2009.", "content": "Molecular epidemiology of noroviruses detected in seasonal outbreaks of acute nonbacterial gastroenteritis in Osaka City, Japan, from 1996-1997 to 2008-2009. In seasons from 1996-1997 through 2008-2009, noroviruses (NoVs) were detected in 505 outbreaks (71%) of nonbacterial gastroenteritis in Osaka City, Japan using molecular diagnosis with reverse transcription (RT)-PCR or real-time RT-PCR. The occurrences of NoV-associated outbreaks were related with the cold season during November-March (85.3%), and occasionally small epidemics of NoVs occurring during April-June were observed. Oyster-associated outbreaks were dominant transmission modes (25-61.1%) before the 2003-2004 season, and decreased (5-20.5%) from the 2003-2004 season, although outbreaks attributable to food-borne transmission (except for oysters) and person-to-person contact increased from the 2003-2004 season. The NoV strains were characterized into genotypes based on sequence analysis of partial capsid regions. Genotyping analyses identified at least 30 genotypes (12 in genogroup I [GI] and 18 in genogroup II [GII]) of NoV. The most common genotype was GII.4 (44.6%), followed in order by GII.3, GII.6, GII.2, and GII.5. The number of GII.4 NoVs increased greatly from the 2003-2004 season, eventually comprising a large share among the NoV- associated outbreaks (97.4%) of the 2006-2007 season. Occasional increased prevalence of genotypes other than GII.4 was observed during this study period. This study showed the appearance, spread, and disappearance of various genotypes and the change of NoV epidemic in a limited geographic region. Continuous NoV molecular surveillance is important for understanding NoV infections and for improving measures for their control and prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981799"}
{"pmid": "20981806", "title": "Rituximab for patients with myopathy associated with anti-signal recognition particle antibodies: comment on the article by Valiyil et al.", "content": "Rituximab for patients with myopathy associated with anti-signal recognition particle antibodies: comment on the article by Valiyil et al.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981806"}
{"pmid": "20981807", "title": "Care needs to be taken when reviewing malignancy data reported from observational studies: comment on the article by Onel and Onel.", "content": "Care needs to be taken when reviewing malignancy data reported from observational studies: comment on the article by Onel and Onel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981807"}
{"pmid": "20981804", "title": "BK virus sequences in specimens from aborted fetuses.", "content": "BK virus sequences in specimens from aborted fetuses. Given the conflicting results of the few published studies, the aim of this retrospective molecular-based study of 10 aborted fetuses that underwent complete autopsy and 10 placentas was carried out to determine whether BK polyomavirus (BKV) can be transmitted transplacentally. The interruption of pregnancy was due to a miscarriage (five cases) or a prenatal diagnosis of severe intrauterine malformations (five cases). Samples from the brain, heart, lung, thymus, liver, and kidney were taken from each fetus, and two samples were obtained from all of the placentas. The presence of BKV was investigated by means of PCR using primers specific for the transcription control region (TCR) and viral capsidic protein 1 (VP1) and DNA extracted from formalin-fixed, paraffin-embedded tissue. BKV genome was detected in 22 of 60 samples (36.6%) from seven fetuses (70%), regardless of the cause of abortion: VP1 was amplified in 12 samples (54%), TCR in seven (32%), and both in three (14%). VP1 was also detected in one placental sample. BKV sequences were most frequently detected in heart and lung (five cases), but sequence analyses of TCR and VP1 revealed a high degree of genomic variability among the samples taken from different organs and the placenta. These results indicate that BKV can cross the placenta during pregnancy and become latent in fetal organs other than the kidney and brain (previously considered the main targets of BKV latency). This may happen in early pregnancy and does not seem to be associated with an increased risk of abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981804"}
{"pmid": "20981808", "title": "Gait modification strategies for altering medial knee joint load: a systematic review.", "content": "Gait modification strategies for altering medial knee joint load: a systematic review. To evaluate the effect of gait modification strategies on the external knee adduction moment (KAM), a marker of medial knee joint load; determine potentially adverse effects; assess the methodologic quality; and identify areas of future research. Five electronic databases were searched. Studies evaluating the effects of gait modifications on the KAM in either healthy individuals or those with knee osteoarthritis (OA) were included. Methodologic quality was evaluated by 2 reviewers using the Downs and Black checklist. Twenty-four studies met the inclusion criteria, exploring 14 different gait modifications of varying sample sizes, age groups, and OA classifications. Contralateral cane use, increased step width, medial knee thrust, increased hip internal rotation, weight transfer to the medial foot, and increased lateral trunk lean demonstrated KAM reductions. Tai Chi gait, ipsilateral cane use, Nordic walking poles, and increased knee flexion exhibited increases in the KAM, demonstrating a potential detriment to their use. The effects of reduced stride length, as well as increases and reductions in either toe-out or gait speed, were inconsistent across the studies and gait cycle. This review demonstrates that some gait modifications have the ability to alter knee load. Future research is required to determine the magnitude of modification required to maximize beneficial effects, the best method of training, long-term patient adherence, and if these biomechanical changes can translate into clinically relevant changes in symptoms or disease progression risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981808"}
{"pmid": "20981809", "title": "Hepatitis C virus-associated polyarteritis nodosa.", "content": "Hepatitis C virus-associated polyarteritis nodosa. To analyze the main characteristics and outcome of polyarteritis nodosa (PAN)-type vasculitis associated with hepatitis C virus (HCV). We reported the characteristics and outcome of 31 patients chronically infected with HCV who satisfied the American College of Rheumatology and Chapel Hill criteria for PAN, seen between 1990 and 2009 in a university center. Among a cohort of 161 patients with HCV-related vasculitis, 31 (19.3%) were diagnosed as having PAN. The median age was 64.5 years (interquartile range 49.5-70.5 years), with 54.8% women. Compared with HCV-associated mixed cryoglobulinemia (HCV-MC) vasculitis, HCV-PAN displayed a more severe and acute clinical presentation with more frequent fever and weight loss (P < 0.0001), severe hypertension (P = 0.0006), gastrointestinal tract involvement (P < 0.0001), severe acute sensory-motor multifocal mononeuropathy (P < 0.0001), kidney and liver microaneurysms (P = 0.002), and increased C-reactive protein level (P < 0.0001). Complete clinical remission of vasculitis was achieved in 79.3% of HCV-PAN patients compared to 57.5% of HCV-MC patients (P = 0.05). In multivariate analysis, skin involvement (odds ratio [OR] 2.81, 95% confidence interval [95% CI] 1.27-6.33) and PAN-type vasculitis (OR 3.01, 95% CI 1.16-8.96) were independently associated with a complete clinical response of HCV vasculitis. A glomerular filtration rate <70 ml/minute (OR 0.54, 95% CI 0.24-1.21) was negatively associated with a complete clinical response of HCV vasculitis. The 5-year survival rate was 86% in the entire cohort, regardless of the vasculitis type. HCV-PAN accounts for 19.3% of our cohort of HCV vasculitis. HCV-PAN displays a more severe and acute clinical presentation and a higher rate of clinical remission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981809"}
{"pmid": "20981811", "title": "Human immunodeficiency virus infection presenting as an unusual arthropathy.", "content": "Human immunodeficiency virus infection presenting as an unusual arthropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981811"}
{"pmid": "20981812", "title": "Changes in physical activity and health-related quality of life during the first year after total knee arthroplasty.", "content": "Changes in physical activity and health-related quality of life during the first year after total knee arthroplasty. Despite its impact on the overall outcome and health-related quality of life (HRQOL) after knee surgery, physical activity has not been investigated directly using accelerometry or step monitoring during the first year after total knee arthroplasty (TKA) due to osteoarthritis (OA). Therefore, the present study aimed to evaluate the development of physical activity over 12 months after surgery and its relationship to clinical outcome and HRQOL. Fifty-three patients scheduled for primary TKA due to OA were measured with the DynaPort ADL monitor and a step activity monitor preoperatively and at 2, 6, and 12 months of followup. Clinical outcome and HRQOL were investigated using the American Knee Society Score (KSS) and Short Form 36 (SF-36) health survey. Physical activity increased significantly within 12 months of followup (from mean ± SD 4,993 ± 2,170 gait cycles preoperatively to 5,932 ± 2,111 gait cycles; P = 0.003). Clinical outcome and HRQOL improved from baseline (mean ± SD KSS 88.9 ± 21.4, mean ± SD SF-36 43.1 ± 18.4) to 12 months of followup (mean ± SD KSS 188.6 ± 10.9; P = 0.001 and mean ± SD SF-36 82.5 ± 15.9; P = 0.001). Physical activity parameters did not correlate with clinical outcome. TKA offers profound improvements of physical activity for the majority of patients. Despite these improvements and the excellent clinical outcome, most patients do not reach the level of physical activity reported for healthy subjects. The activity level after treatment seems to be influenced by physical activity behavior prior to surgery rather than by the treatment itself.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981812"}
{"pmid": "20981826", "title": "Simple and efficient transgenesis with I-SceI meganuclease in the newt, Cynops pyrrhogaster.", "content": "Simple and efficient transgenesis with I-SceI meganuclease in the newt, Cynops pyrrhogaster. Newts have been recognized as an ideal model for body-parts regeneration after traumatic injury since the 18(th) century. However, molecular mechanisms underlying regeneration remain a mystery because of technical limitations. In the current study, to break this obstacle, we established a simple and efficient transgenic protocol for the newt Cynops pyrrhogaster by adapting an I-SceI microinjection technique, as well as a two-aquarium-tank (TAT) system that allows us to constantly obtain fertilized eggs in the laboratory for transgenesis. Following our protocol, ∼ 20% of injected embryos would exhibit non-mosaic widespread transgene expression and survive beyond metamorphosis. This anticipated success rate is about 10 times higher than that obtained by previous protocols, reaching a practical level. Therefore, our transgenic protocol in conjunction with the TAT-system could provide a key technique to open the way to uncover the long mystery underlying body-parts regeneration of newts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981826"}
{"pmid": "20981828", "title": "Dynamic expression patterns of 6-O endosulfatases during zebrafish development suggest a subfunctionalisation event for sulf2.", "content": "Dynamic expression patterns of 6-O endosulfatases during zebrafish development suggest a subfunctionalisation event for sulf2. The 6-O-endosulfatase enzymes (Sulfs) edit the final sulfation pattern and function of heparan sulfate (HS) by removal of 6-O-sulfate groups from the chain. To date, two mammalian sulf genes have been identified that regulate many signalling pathways during embryonic development. In zebrafish a sulf1 ortholog and duplicate copies of the mammalian sulf2 gene, sulf2a and sulf2, have been identified, which contain conserved motifs characteristic of vertebrate sulf genes. Zebrafish sulf1 and sulf2a are broadly expressed in the central nervous system (CNS) and non-neuronal tissue including heart, somite boundaries, olfactory system, and otic vesicle, whereas sulf2 expression is almost entirely restricted to the CNS. The duplicate copies of sulf2 have distinct expression patterns, which together mirror that of mouse sulf2, suggesting duplication in the teleost lineage has been followed by subfunctionalisation, whereby both genes need to be preserved by selection to ensure the ancestral gene's expression profile and function is maintained.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981828"}
{"pmid": "20981829", "title": "Lef1 controls patterning and proliferation in the posterior lateral line system of zebrafish.", "content": "Lef1 controls patterning and proliferation in the posterior lateral line system of zebrafish. The embryonic development of the posterior lateral line of zebrafish involves the migration from head to tail of a primordium comprising approximately 100 cells, and the deposition at regular intervals of presumptive mechanosensory organs (neuromasts). Migration depends on the presence of chemokine SDF1 along the pathway, and on the asymmetrical distribution of chemokine receptors CXCR4 and CXCR7 in the primordium. Primordium polarization depends on Wnt signaling in the leading region. Here, we examine the role of a major effector of Wnt signaling, lef1, in this system. We show that, although its inactivation has no overt effect on the expression of cxcr4b and cxcr7b, lef1 contributes to their control. We also show that cell proliferation, which ensures constant primordium size despite successive rounds of cell deposition, is reduced upon lef1 inactivation. Because of this defect, the primordium runs short of cells and vanishes before the line has been completed. We conclude that lef1-mediated Wnt signaling is involved in various aspects of primordium migration, although part of this implication is masked by a high level of developmental redundancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981829"}
{"pmid": "20981813", "title": "Distal extremity pain as a presenting feature of Fabry's disease.", "content": "Distal extremity pain as a presenting feature of Fabry's disease. Fabry's disease (FD) is an X-linked lysosomal storage disease. Distal extremity pain can be an early finding and renal, cardiac, and cerebrovascular complications may lead to complications and mortality. Treatment is now available for these patients, who may not be diagnosed correctly for years if the neuropathic nature of the pain is not recognized. The aim of our study was to describe early clinical features in a cohort of patients with FD and to emphasize the importance of distal extremity pain for early diagnosis. The medical charts of 35 patients with FD followed in a single center were reviewed. When data were incomplete, a detailed pain questionnaire was sent to patients. Nonresponders were contacted by telephone. Distal extremity pain was present in the majority of cases (25 of 35). The mean age at diagnosis of FD was 43.5 years (range 5-77 years). Distal extremity pain was more prevalent in males than females and occurred mostly in childhood or adolescence. When present at onset, the disease progressed with subsequent organ system involvement. Misdiagnoses were frequent and included growing pains, juvenile idiopathic arthritis, connective tissue disease, and gout. Clinical manifestations of FD, including episodes of severe pain in the feet and hands, often start in childhood. Distal extremity pain may be the only symptom for a considerable period of time. Patients may be wrongly labeled as having rheumatologic conditions, resulting in long diagnostic and therapeutic delays. Rheumatologists should be aware of the clinical aspects of FD and include it in the differential diagnosis of distal extremity pain in childhood and adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981813"}
{"pmid": "20981830", "title": "GPR56 is essential for testis development and male fertility in mice.", "content": "GPR56 is essential for testis development and male fertility in mice. Testis development is critical for male fertility and continuation of the mammalian species. Essential structural components of testes are seminiferous tubules, which are lined by Sertoli cells and provide nutrients and physical protection for the maturation of sperm. Seminiferous tubule formation is initiated in embryos as testis cords and relies on their remodeling for maturation during development. Recently, three-dimensional image analyses showed that testis cords in different parts of embryonic gonads undergo distinct remodeling processes. How this asymmetric remodeling is regulated has not been investigated. We report here that the absence of an adhesion G protein-coupled receptor, GPR56, leads to partial disruption of seminiferous tubules and reduced fertility in male mice. The defects appear to originate asymmetrically in embryonic gonads, but subsequent to the initial establishment of testis cords, suggesting that GPR56 might act to establish a spatial and/or temporal cue for asymmetric cord remodeling during male gonad development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981830"}
{"pmid": "20981832", "title": "The dual histone demethylase KDM7A promotes neural induction in early chick embryos.", "content": "The dual histone demethylase KDM7A promotes neural induction in early chick embryos. Neural induction is the initial event of nervous system development during which part of the ectoderm is specified to become the embryonic neural plate. The biological roles of histone modification enzymes in the neural induction of early embryos remain unclear. Here, we show that an evolutionarily conserved dual histone demethylase KDM7A (KIAA1718) is predominantly expressed in epiblast cells of the primitive streak in early chick embryos. Overexpression of KDM7A in chick embryos leads to expansion of the neural plate, whereas knockdown of the gene impairs formation of the neural plate. We also show that KDM7A regulates Fgf4 expression in the primitive streak and that co-electroporation of a chick Fgf4 expression vector with KDM7A siRNA rescues the neural induction defect in chick embryos. Taken together, these results reveal an important role for histone demethylases in the determination of neural fate, and they highlight the mechanistic complexity of neural induction in early embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981832"}
{"pmid": "20981834", "title": "Expression of the transcription factor Olig2 in proliferating cells in the adult zebrafish telencephalon.", "content": "Expression of the transcription factor Olig2 in proliferating cells in the adult zebrafish telencephalon. The telencephalon of the adult zebrafish is highly proliferative: Dividing cells are found along the entire ventricular zone and in the parenchyma. Here, we investigated the relation of proliferating cells in the telencephalic parenchyma to the oligodendrocyte lineage. We find at least three different cell types of the oligodendrocyte lineage (olig2-and sox10-positive) in the parenchyma of the telencephalon: Proliferating progenitors (PCNA-positive), including a subpopulation of slowly dividing progenitors (long term label-retaining), as well as mature oligodendrocytes (Mbp-positive) and presumptive quiescent OPCs (neither Mbp-positive nor proliferating). Furthermore, in the ventricular zone (in and ventral to the RMS), two different subpopulations of olig2-positive cell populations are present. Since these ventricular olig2-positive cells do not express the oligodendrocyte marker sox10, it is not clear whether these cells indeed belong to the oligodendrocyte lineage. Taken together, we detected at least five different classes of olig2-positive cells in the telencephalon of the adult zebrafish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981834"}
{"pmid": "20981831", "title": "Gsk3β is required in the epithelium for palatal elevation in mice.", "content": "Gsk3β is required in the epithelium for palatal elevation in mice. In Wnt/β-catenin signaling pathway, Gsk3β functions to facilitate β-catenin degradation. Inactivation of Gsk3β in mice causes a cleft palate formation, suggesting an involvement of Wnt/β-catenin signaling during palatogenesis. In this study, we have investigated the expression pattern, tissue-specific requirement and function of Gsk3β during mouse palatogenesis. We showed that Gsk3β is primarily expressed in the palatal epithelium, particularly in the medial edge epithelium overlapping with β-catenin. Tissue-specific gene inactivation studies demonstrated an essential role for Gsk3β in the epithelium for palate elevation, and disruption of which contributes to cleft palate phenotype in Gsk3β mutant. We observed that expression of Aixn2, a direct target gene of Wnt/β-catenin signaling, is ectopically activated in the mutant tongue, but not in the palate. Our results indicate that Gsk3β is an intrinsic regulator required in the epithelium for palate elevation, and could act through a pathway independent of Wnt/β-catenin signaling to regulate palate development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981831"}
{"pmid": "20981833", "title": "Embryonic coronary vasculogenesis and angiogenesis are regulated by interactions between multiple FGFs and VEGF and are influenced by mesenchymal stem cells.", "content": "Embryonic coronary vasculogenesis and angiogenesis are regulated by interactions between multiple FGFs and VEGF and are influenced by mesenchymal stem cells. In embryonic hearts explanted on collagen gels, epicardial cells delaminate and form vascular tubes, thus providing a model for coronary tubulogenesis. Using this model, we show that fibroblast growth factors (FGFs) 1, 2, 4, 8, 9, and 18 contribute to tubulogenesis and that the availability of multiple FGFs provides the optimal tubulogenic response. Moreover, the FGF effects are vascular endothelial growth factor (VEGF) -dependent, while VEGF-induced tubulogenesis requires FGF signaling. The number of endothelial cells (ECs) is increased by all of the FGFs, while EC migration is significantly enhanced only by FGF-2 and FGF-18. Finally, addition of embryonic mesenchymal stem cells (EMSC) to the explants markedly enhances EC numbers and a 23-fold increase in stromal derived factor-1α (SDF-1α), which is FGF dependent. Both explants and EMSCs produce SDF-1α. In conclusion, coronary tubulogenesis of embryonic epicardium: (1) is responsive to many FGF family members, (2) requires both FGF and VEGFA signaling, and (3) is responsive to EMSCs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981833"}
{"pmid": "20981837", "title": "Traits-based approaches in bioassessment and ecological risk assessment: strengths, weaknesses, opportunities and threats.", "content": "Traits-based approaches in bioassessment and ecological risk assessment: strengths, weaknesses, opportunities and threats. We discuss the application of traits-based bioassessment approaches in retrospective bioassessment as well as in prospective ecological risk assessments in regulatory frameworks. Both approaches address the interaction between species and stressors and their consequences at different levels of biological organization, but the fact that a specific species may be less abundant in a potentially impacted site compared with a reference site is, regrettably, insufficient to provide diagnostic information. Species traits may, however, overcome the problems associated with taxonomy-based bioassessment. Trait-based approaches could provide signals regarding what environmental factors may be responsible for the impairment and, thereby, provide causal insight into the interaction between species and stressors. For development of traits-based (TBA), traits should correspond to specific types of stressors or suites of stressors. In this paper, a strengths, weaknesses, opportunities, and threats (SWOT) analysis of TBA in both applications was used to identify challenges and potentials. This paper is part of a series describing the output of the TERA (Traits-based ecological risk assessment: Realising the potential of ecoinformatics approaches in ecotoxicology) Workshop held between 7 and 11 September, 2009, in Burlington, Ontario, Canada. The recognized strengths were that traits are transferrable across geographies, add mechanistic and diagnostic knowledge, require no new sampling methodology, have an old tradition, and can supplement taxonomic analysis. Weaknesses include autocorrelation, redundancy, and inability to protect biodiversity directly. Automated image analysis, combined with genetic and biotechnology tools and improved data analysis to solve autocorrelation problems were identified as opportunities, whereas low availability of trait data, their transferability, their quantitative interpretation, the risk of developing nonrelevant traits, low quality of historic databases, and their standardization were listed as threats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981837"}
{"pmid": "20981835", "title": "Framework for traits-based assessment in ecotoxicology.", "content": "Framework for traits-based assessment in ecotoxicology. A key challenge in ecotoxicology is to assess the potential risks of chemicals to the wide range of species in the environment on the basis of laboratory toxicity data derived from a limited number of species. These species are then assumed to be suitable surrogates for a wider class of related taxa. For example, Daphnia spp. are used as the indicator species for freshwater aquatic invertebrates. Extrapolation from these datasets to natural communities poses a challenge because the extent to which test species are representative of their various taxonomic groups is often largely unknown, and different taxonomic groups and chemicals are variously represented in the available datasets. Moreover, it has been recognized that physiological and ecological factors can each be powerful determinants of vulnerability to chemical stress, thus differentially influencing toxicant effects at the population and community level. Recently it was proposed that detailed study of species traits might eventually permit better understanding, and thus prediction, of the potential for adverse effects of chemicals to a wider range of organisms than those amenable for study in the laboratory. This line of inquiry stems in part from the ecology literature, in which species traits are being used for improved understanding of how communities are constructed, as well as how communities might respond to, and recover from, disturbance (see other articles in this issue). In the present work, we develop a framework for the application of traits-based assessment. The framework is based on the population vulnerability conceptual model of Van Straalen in which vulnerability is determined by traits that can be grouped into 3 major categories, i.e., external exposure, intrinsic sensitivity, and population sustainability. Within each of these major categories, we evaluate specific traits as well as how they could contribute to the assessment of the potential effects of a toxicant on an organism. We then develop an example considering bioavailability to explore how traits could be used mechanistically to estimate vulnerability. A preliminary inventory of traits for use in ecotoxicology is included; this also identifies the availability of data to quantify those traits, in addition to an indication of the strength of linkage between the trait and the affected process. Finally, we propose a way forward for the further development of traits-based approaches in ecotoxicology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981835"}
{"pmid": "20981841", "title": "A turning point in the fight against HIV.", "content": "A turning point in the fight against HIV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981841"}
{"pmid": "20981855", "title": "Effect of a human pharmaceutical carbamazepine on antioxidant responses in brain of a model teleost in vitro: an efficient approach to biomonitoring.", "content": "Effect of a human pharmaceutical carbamazepine on antioxidant responses in brain of a model teleost in vitro: an efficient approach to biomonitoring. Residual pharmaceuticals are generally recognized as relevant sources of aquatic environmental pollutants. In this study, the effects of carbamazepine (CBZ) on the antioxidant defense system in the brain of rainbow trout in vitro were studied. The brain homogenates were incubated with various concentrations of CBZ (1.0 µg l⁻¹, 0.2 mg l⁻¹ or 2.0 mg l⁻¹) for 0, 60, 120 min. After incubation, oxidative stress indices (lipid peroxidation and carbonyl protein), antioxidant enzymes (superoxide dismutase, glutathione reductase and glutathione peroxidase) and nonenzymatic antioxidant (reduced glutathione) in each samples were measured. Based on the results, the brain homogenates performed adaptive responses to CBZ-induced stress at environmental concentration (1.0 µg l⁻¹). With increased CBZ concentrations (0.2 or 2.0 mg l⁻¹), oxidative stress was apparent as reflected by the significant higher levels of oxidative indices, together with the significant inhibition of all antioxidant enzymes activities and reduced glutathione content. Compared with previous studies in vivo, the brain homogenates showed more sensitive antioxidant responses to CBZ stress. In conclusion, the brain homogenates of rainbow trout could be used as an efficient model system in aquatic risk assessment, but more detailed laboratory studies are needed before these findings could be established as special biomarkers for monitoring residual pharmaceuticals in aquatic environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981855"}
{"pmid": "20981856", "title": "Acrylonitrile induced apoptosis via oxidative stress in neuroblastoma SH-SY5Y cell.", "content": "Acrylonitrile induced apoptosis via oxidative stress in neuroblastoma SH-SY5Y cell. Acrylonitrile (ACN) is a chemical that is widely used in the production of plastics, acrylic fibers, synthetic rubbers and resins. It has been reported that ACN can cause oxidative stress, a condition which is well recognized as an apoptotic initiator; however, information regarding ACN-induced apoptosis is limited. This present study investigated whether ACN induces apoptosis in human neuroblastoma SH-SY5Y cells, and whether its apoptotic induction involves oxidative stress. The results showed that ACN caused activation of caspase-3, a key enzyme involved in apoptosis, in a dose- and time-dependent manner. Detection of sub-G1 apoptotic cell death and apoptotic nuclear condensation revealed that ACN caused an increase in the number of apoptotic cells indicating ACN induces apoptosis in SH-SY5Y cells. ACN dose- and time-dependently increased the level of proapoptotic protein, Bax. Pretreatment with N-acetylcysteine (NAC), an antioxidant, attenuated caspase-3 activation by ACN, as evidenced by a reduction in proteolysis of PARP, a known caspase-3 substrate, as well as in the number of sub-G1 apoptotic cells. Moreover, induction of Bax by ACN was abolished by NAC. Taken together, the results indicate that ACN induces apoptosis in SH-SY5Y cells via a mechanism involving generation of oxidative stress-mediated Bax induction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981856"}
{"pmid": "20981857", "title": "Thymocytes are activated by toluene inhalation through the transcription factors NF-κB, STAT5 and NF-AT.", "content": "Thymocytes are activated by toluene inhalation through the transcription factors NF-κB, STAT5 and NF-AT. Toluene has been extensively examined for effects on the central nervous system. To investigate the influence of low-level inhalation of toluene on the naive immune cells, male C3H/HeN mice were exposed to filtered air (control) and 50 ppm of toluene for 3 weeks. Low-level exposure resulted in (1) increased proliferation of thymocytes, (2) IL-2 production induced in thymocytes and (3) activation of the transcription factors NF-κB, STAT5 and NF-AT in thymocytes. These results suggest that thymocytes are sensitive cells and T cell activators are candidates for biomarkers for low-level exposure to toluene on naive immune cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981857"}
{"pmid": "20981858", "title": "Endogenous antioxidants and nasal human epithelium response to air pollutants: genotoxic and inmmuno-cytochemical evaluation.", "content": "Endogenous antioxidants and nasal human epithelium response to air pollutants: genotoxic and inmmuno-cytochemical evaluation. Nasal epithelium is a source for identifying atmospheric pollution impact. Antioxidants play a relevant role in the protection of the cells from environmental injury, but scarce information is available about the interaction of endogenous antioxidants and genotoxic damage in nasal epithelium from urban populations highly exposed to traffic-generated air pollutants. An immunocytochemical and genotoxic evaluation was implemented in nasal cell epithelium in a population chronically exposed to atmospheric pollution from autumn 2004 to autumn 2005. Superoxide dismutase (SOD) and Catalase (CAT) were evaluated in nasal scrapings by morphometry and genotoxicity by comet assay. An increase in DNA damage correlates with a decrease in SOD and CAT in nasal cells during autumn and the inverse result was observed during summer (R = 0.88). Not only should exogenous antioxidant supplements be encouraged, but also a healthy diet to strengthen intracellular defenses against oxidative stress induced by exposure to air pollutants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981858"}
{"pmid": "20981859", "title": "Chrysoeriol isolated from Eurya cilliata leaves protects MC3T3-E1 cells against hydrogen peroxide-induced inhibition of osteoblastic differentiation.", "content": "Chrysoeriol isolated from Eurya cilliata leaves protects MC3T3-E1 cells against hydrogen peroxide-induced inhibition of osteoblastic differentiation. Chrysoeriol is a flavonoid compound found in several tropical medicinal plants. To elucidate the protective effects of chrysoeriol isolated from Eurya cilliata on the response of osteoblasts to oxidative stress, osteoblastic MC3T3-E1 cells were incubated with chrysoeriol and/or H₂O₂, and markers of osteoblast function and oxidative damage were examined. Chrysoeriol treatment significantly (P < 0.05) reversed the cytotoxic effect of H₂O₂ and increased collagen content, alkaline phosphatase activity and calcium deposition of osteoblasts in the presence of H₂O₂. These effects were blocked by ICI182780, suggesting that chrysoeriol's effect might be partly involved in estrogen action. Moreover, H₂O₂-induced reduction of osteocalcin was recovered in the presence of chrysoeriol. Chrysoeriol significantly (P < 0.05) decreased the production of receptor activator of nuclear factor-κB ligand, interleukin-6, protein carbonyl and malondialdehyde of MC3T3-E1 cells in the presence of H₂O₂. These results demonstrate that chrysoeriol isolated from E. cilliata can protect osteoblasts from oxidative stress-induced toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981859"}
{"pmid": "20981860", "title": "Levels of organic and inorganic mercury in human blood predicted from measurements of total mercury.", "content": "Levels of organic and inorganic mercury in human blood predicted from measurements of total mercury. The toxicologically relevant mercury species inorganic and organic Hg in blood are frequently determined by separate measurements of total Hg and of inorganic Hg, with their difference indicating organic Hg. It is shown that the different partition of inorganic and organic Hg between erythrocytes and plasma (e/p ratio) can be used to calculate the concentrations of either Hg species in either blood constituent from measurement of total Hg only. This was tested on the blood of different groups of volunteers. The calculated concentrations of inorganic and organic Hg in cells and plasma were then compared by linear regression with their previously measured counterparts. An accurate prediction has been found for individual levels of inorganic Hg in plasma and organic Hg in cells. These calculated levels were little affected by variations of the e/p ratios. The coincidence between calculated and measured levels of inorganic Hg in cells and organic Hg in plasma was more sensitive to alterations of the e/p ratios. In conclusion, the relevant concentrations of inorganic Hg in plasma and organic Hg in cells can reliably be calculated from measurements of total Hg and from assumed e/p ratios. This means a sizeable reduction of analytical work, and also provides specific information in cases of low-level co-exposure to both Hg species. Besides the possibility to introduce automated analyses of total Hg in mercury speciation in blood, the proposed calculation scheme has the potential to easily enlarge the data base in epidemiological and toxicological surveys of mercury exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981860"}
{"pmid": "20981862", "title": "Validation of the intact rat weanling uterotrophic assay with notes on the formulation and analysis of the positive control chemical in vehicle.", "content": "Validation of the intact rat weanling uterotrophic assay with notes on the formulation and analysis of the positive control chemical in vehicle. The intact female weanling version in the Organization for Economic Cooperation and Development (OECD) uterotrophic assay Test Guideline (TG) 440 is proposed as an alternative to the adult ovariectomized female version, because it does not involve surgical intervention (vs the ovariectomized version) and detects direct/indirect-acting estrogenic/anti-estrogenic substances (vs the ovariectomized version which detects only direct-acting estrogenic/anti-estrogenic substances binding to the estrogen receptor). This validation study followed OECD TG 440, with six female weanling rats (postnatal day 21) per dose group and six treatment groups. Females were weighed and dosed once daily by oral gavage for three consecutive days, with one of six doses of 17α-ethinyl estradiol in corn oil at 5 ml kg⁻¹ at 0 and 0.1-10 µg kg⁻¹ per day. On postnatal day 24, the juvenile females were euthanized by CO₂ asphyxiation, weighed, livers weighed and uteri weighed wet and blotted. The presence or absence of vaginal patency was recorded. Absolute and relative (to terminal body weight) uterine wet and blotted weights and uterine luminal fluid weights were significantly increased at 3.0 and 10.0 (both P < 0.01) µg kg⁻¹ per day, and increased to ~140% of control values at 1.0 µg kg⁻¹ per day (not statistically significantly). In vivo body weights, weight changes, feed consumption, liver weights and terminal body weights were unaffected. Vaginal patency was not acquired in any female at any dose, although vaginal puckering was observed in one female at 10.0 µg kg⁻¹ per day. Therefore, this intact weanling uterotrophic assay is validated in our laboratory for use under US and European endocrine toxicity testing programs/legislation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981862"}
{"pmid": "20981861", "title": "Preliminary evaluation of acute toxicity of (188) Re-BMEDA-liposome in rats.", "content": "Preliminary evaluation of acute toxicity of (188) Re-BMEDA-liposome in rats. Liposomes can selectively target cancer sites and carry payloads, thereby improving diagnostic and therapeutic effectiveness and reducing toxicity. To evaluate therapeutic strategies, it is essential to use animal models reflecting important safety aspects before clinical application. The objective of this study was to investigate acute radiotoxicity of ¹⁸⁸Re-N,N-bis (2-mercaptoethyl)-N',N'-diethylethylenediamine (BMEDA)-labeled pegylated liposomes (¹⁸⁸Re-BMEDA-liposome) in Sprague-Dawley rats. Rats were administered with ¹⁸⁸Re-BMEDA-liposome, normal saline as blank or non-radioactive liposome as vehicle control via intravenous injection and observed for 14 days. Examinations were conducted with respect to mortality, clinical signs, food consumption, body weight and hematological and biochemical analyses. In addition, gross necropsy, histopathological examinations and cytogenetic analyses were also performed. None of the rats died and no clinical sign was observed during the 14-day study period. Rats administered with ¹⁸⁸Re-BMEDA-liposome at dosage of 185 MBq displayed a significant weight loss compared with the control from study day (SD) 1 to SD 4, and the white blood cell count reduced to 5-10% of initial value (female: 18.55 ± 6.58 to 0.73 ± 0.26 x 10³  µl⁻¹; male: 14.52 ± 5.12 to 1.43 ± 0.54 x 10³  µl⁻¹) 7 days-post injection, but were found to have recovered on SD 15. There were no significant differences in biochemical parameters and histopathological assessments between the ¹⁸⁸Re-BMEDA-liposome-treated and control groups. The frequencies of dicentric chromosomes were associated with dosage of ¹⁸⁸Re-BMEDA-liposome. The information generated from this study on acute toxicity will serve as a safety reference for further subacute toxicity study in rats and human clinical trials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981861"}
{"pmid": "20981863", "title": "Naturally contaminated shellfish samples: quantification of diarrhetic shellfish poisoning toxins in unhydrolysed and hydrolysed extracts and cytotoxicity assessment.", "content": "Naturally contaminated shellfish samples: quantification of diarrhetic shellfish poisoning toxins in unhydrolysed and hydrolysed extracts and cytotoxicity assessment. Contamination of shellfish from the Portuguese coast with diarrhetic shellfish poisoning (DSP) toxins is a recurrent event, with most of the commercial bivalves contaminated with high percentages of esters of okadaic acid (OA) and dinophysistoxin-2 (DTX2). This report describes the quantification of DSP toxins in unhydrolysed and hydrolysed extracts of several cockle and mussel samples naturally contaminated and the evaluation of their cytotoxicity profiles in V79 cells. The quantification of the acyl esters in the shellfish samples involved the cleavage of the ester bond through alkaline hydrolysis and the release of the parent toxins OA and DTX2. Unhydrolysed and hydrolysed extracts were then analyzed by liquid chromatography (LC) coupled with mass spectrometry (MS) for the detection and quantification of DSP toxins. The cytotoxicity of the analysed extracts was evaluated using the MTT reduction assay and compared with the cytotoxicity presented by different concentrations of OA standard (1-100 nM). OA exhibited marked cytotoxic effects and decreased cell viability in a dose dependent mode, with an IC₅₀ of 27 nM. The cytotoxicity pattern of unhydrolysed extracts was clearly dependent on the concentration of free toxins. Moreover, the cytotoxicity of the esterified toxins present was revealed after their conversion into free toxins by alkaline hydrolysis. For the hydrolysed extracts of cockles and mussels, the cytotoxicity presented was mainly related to the concentration of OA and DTX2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981863"}
{"pmid": "20981865", "title": "Congenital megalourethra: prenatal diagnosis and postnatal/autopsy findings in 10 cases.", "content": "Congenital megalourethra: prenatal diagnosis and postnatal/autopsy findings in 10 cases. Congenital megalourethra is a rare urogenital malformation characterized by dilation and elongation of the penile urethra associated with absence or hypoplasia of the corpora spongiosa and cavernosa. Postnatal complications include voiding and erectile dysfunction as well as renal insufficiency and pulmonary hypoplasia. To date, only a few prenatally diagnosed cases have been reported. We report on 10 cases diagnosed prenatally and their postnatal/autopsy findings. The study involved retrospective chart review of all cases diagnosed antenatally in three tertiary care centers over 5 years. Antenatal ultrasound images and medical records from obstetrics, genetics, urology and nephrology were reviewed. Ten fetuses with megalourethra were identified at a median gestational age of 19 (range, 13-24) weeks and all were confirmed postnatally or at autopsy. Three pregnancies were terminated and seven continued. All cases presented with a distended bladder and megalourethra and all cases had normal karyotype. Of seven liveborn babies, one died neonatally of pulmonary hypoplasia. All six infants alive at the time of writing had a dysfunctional urethra and three suffered from impaired or end-stage renal disease. Associated anomalies were found in half of the cases. Congenital megalourethra is caused by abnormal development or hypoplasia of the penile erectile tissue, secondary to distal urethral obstruction. When the amniotic fluid volume is normal, survival is possible. However, all liveborn infants have voiding and renal dysfunction and sexual dysfunction is expected. Megalourethra should be considered in all male fetuses presenting prenatally with megacystis and detailed fetal ultrasonography should look for an elongated and/or distended phallic structure as well as any associated anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981865"}
{"pmid": "20981864", "title": "Pretreatment for acute exposure to diisopropylfluorophosphate: in vivo efficacy of various acetylcholinesterase inhibitors.", "content": "Pretreatment for acute exposure to diisopropylfluorophosphate: in vivo efficacy of various acetylcholinesterase inhibitors. Prophylactic administration of reversible acetylcholinesterase (AChE) inhibitors before exposure to organophosphorus compounds (OPCs) can reduce OPC-induced mortality. Pyridostigmine is the only FDA-approved substance for such use. The AChE-inhibitory activity of known AChE inhibitors was quantified in vitro and their in vivo mortality-reducing efficacy was compared, when given prophylactically before the exposure to the OPC diisopropylfluorophosphate (DFP). The IC50 was measured in vitro for the known AChE inhibitors pyridostigmine, physostigmine, ranitidine, tiapride, tacrine, 7-methoxytacrine, amiloride, metoclopramide, methylene blue and the experimental oxime K-27. Their in vivo efficacy, when given as pretreatment, to protect rats from DFP-induced mortality was quantified by determining the relative risk of death (RR) by Cox analysis, with RR = 1 for animals given only DFP, but no pretreatment. Physostigmine was the strongest in vitro AChE-inhibitor (IC50 = 0.012 µ m), followed by 7-methoxytacrine, tacrine, pyridostigmine and methylene blue. Ranitidine (IC50 = 2.5 µ m), metoclopramide and amiloride were in the mid-range. Tiapride (IC50 = 256 µ m) and K-27 (IC50 = 414 µ m) only weakly inhibited RBC AChE activity. Best in vivo protection from DFP-induced mortality was achieved when physostigmine (RR = 0.02) or tacrine (RR = 0.05) was given before DFP exposure, which was significantly superior to the pretreatment with all other tested compounds, except K-27 (RR = 0.18). The mortality-reducing effect of pyridostigmine, ranitidine and 7-methoxytacrine was inferior, but still significant. Tiapride, methylene blue, metoclopramide and amiloride did not significantly improve DFP-induced mortality. K-27 may be a more efficacious alternative to pyridostigmine, when passage into the brain precludes administration of physostigmine or tacrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981864"}
{"pmid": "20981866", "title": "A simple method for large-scale generation of dopamine neurons from human embryonic stem cells.", "content": "A simple method for large-scale generation of dopamine neurons from human embryonic stem cells. Dopamine (DA) neurons derived from human embryonic stem cells (hESCs) are potentially valuable in drug screening and as a possible source of donor tissue for transplantation in Parkinson's disease. However, existing culture protocols that promote the differentiation of DA neurons from hESCs are complex, involving multiple steps and having unreliable results between cultures. Here we report a simple and highly reproducible culture protocol that induces expandable DA neuron progenitors from hESCs in attached cultures. We found that the hESC-derived neuronal progenitors retain their full capacity to generate DA neurons after repeated passaging in the presence of basic fibroblast growth factor (bFGF) and medium conditioned with PA6 stromal cells. Using immunocytochemistry and RT-PCR, we found that the differentiated DA neurons exhibit a midbrain phenotype and express, e.g., Aldh1a, Ptx3, Nurr1, and Lmx1a. Using HPLC, we monitored their production of DA. We then demonstrated that the expanded progenitors are possible to cryopreserve without loosing the dopaminergic phenotype. With our protocol, we obtained large and homogeneous populations of dopaminergic progenitors and neurons. We conclude that our protocol can be used to generate human DA neurons suitable for the study of disease mechanisms, toxicology, drug screening, and intracerebral transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981866"}
{"pmid": "20981867", "title": "Labdane-type diterpenoids from Leonurus heterophyllus and their cholinesterase inhibitory activity.", "content": "Labdane-type diterpenoids from Leonurus heterophyllus and their cholinesterase inhibitory activity. In the course of screening plants used in natural medicines as memory enhancers, a 70% ethanol extract of the aerial parts of Leonurus heterophyllus showed significant AChE inhibitory activity. Bioassay-guided fractionation and repeated column chromatography led to the isolation of a new labdane-type diterpenoids (1), named leoheteronin F, and six known compounds (2-7). The chemical structures of isolated compounds were elucidated based on extensive 1D and 2D NMR spectroscopic data. The isolates 1-7 were investigated in vitro for their anticholinesterase activity using mouse cortex AChE enzyme. Leoheteronin A (5) and leopersin G (7), which possess a 15,16-epoxy group at the side chain, were found to be potent in the inhibition of AChE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981867"}
{"pmid": "20981868", "title": "Cytotoxic effects induced by combination of heliantriol B2 and dequalinium against human leukemic cell lines.", "content": "Cytotoxic effects induced by combination of heliantriol B2 and dequalinium against human leukemic cell lines. Natural occurring compounds are considered an important source of antitumoral agents. In the present study, the cytotoxic potential of three pentacyclic triterpenes isolated from Chuquiraga erinacea (Asteraceae), against the human leukemic cell lines NB4 and K562 was assessed. Heliantriol B2 (HB2) showed the highest cytotoxic activity after 24 h treatment showing IC(50) values of 1.98 ± 0.12 µm and 3.52 ± 0.14 µm for NB4 and K562 cells, respectively. This activity was higher than that of the reference compound dequalinium (DQA). Apoptosis and necrosis induced by HB2 in both NB4 and K562 cell lines were analysed by Annexin V/PI labeling. Mitochondrial alterations including reactive oxygen species (ROS) production and mitochondrial transmembrane potential (ΔΨm) were also tested. The results demonstrated that HB2 induced cell death by apoptosis and necrosis and showed enhanced cytotoxic effects in combination with DQA. Besides, HB2 induced ROS overproduction in NB4 cells and a slight decrease of ΔΨm. Consequently, our findings prompt further studies on the HB2 mechanism of action and its selectivity to tumor cells in order to assess the potential of HB2 as an agent for cancer treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981868"}
{"pmid": "20981869", "title": "Caudatin-2,6-dideoxy-3-O-methy-β-D-cymaropyranoside 1 induced apoptosis through caspase 3-dependent pathway in human hepatoma cell line SMMC7721.", "content": "Caudatin-2,6-dideoxy-3-O-methy-β-D-cymaropyranoside 1 induced apoptosis through caspase 3-dependent pathway in human hepatoma cell line SMMC7721. Caudatin-2,6-dideoxy-3-O-methy-β-D-cymaropyranoside (CDMC), the C-21 steroidal glycoside recently extracted from the traditional Chinese medicinal plant, the root of Cynanchum auriculatum Royle ex Wight (Asclepiadaceae), has been shown to possess potent antitumor properties. However, the bioactivities of CDMC are still largely unknown, especially the antitumor effect and its mechanism. This study investigated the CDMC antitumor effects on human hepatoma cell line SMMC7721 cells by analysis of cell viability, cell cycle phases and apoptosis. The results showed that CDMC inhibited the growth of SMMC7721 cells in a time- and dose-dependent manner and resulted in cell cycle arrest in G(0)/G(1) phase. Furthermore, CDMC induced SMMC7721 cell apoptosis rather than necrosis through caspase 3 activation, and a caspase 3 inhibitor, Ac-DEVD-CHO, could attenuate the apoptosis induced by CDMC. The results suggested that the anticancer activity of CDMC could be attributed partially to its inhibition of cell proliferation and induction of apoptosis associated with caspase 3 activation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981869"}
{"pmid": "20981870", "title": "Osthole improves alcohol-induced fatty liver in mice by reduction of hepatic oxidative stress.", "content": "Osthole improves alcohol-induced fatty liver in mice by reduction of hepatic oxidative stress. The aim of our study was to examine the therapeutic effect of osthole, an active constituent isolated from the fruit of Cnidium monnieri (L.) Cusson, on alcohol-induced fatty liver in mice and investigate its potential mechanisms of treatment. A mouse alcoholic fatty liver model was established by feeding 52% alcohol for 4 weeks. These experimental mice were then treated with osthole 10, 20 and 40 mg/kg for 6 weeks. The levels of serum total cholesterol (TC), triglyceride (TG), low density lipoprotein-cholesterol (LDL-C) and hepatic tissue contents of TC, TG and malondialdehyde (MDA) in osthole-treated groups were significantly decreased, while the level of superoxide dismutase (SOD) was significantly increased compared with the model group. Moreover, the cytochrome P450 (CYP) 2E1 and diacylglycerol acyltransferase (DGAT) mRNA expressions in mouse liver were significantly decreased, and the carnitine palmitoyltransferase (CPT) 1A mRNA expression was increased by osthole treatment. Importantly, the histological evaluation of liver demonstrated that osthole dramatically decreased lipid accumulation. It was concluded that osthole was effective in treating mouse alcoholic fatty liver, and its main mechanisms might be related to reduction of hepatic oxidative stress, including the inhibition of reactive oxygen species (ROS) production, enhancement of antioxidative enzyme activity, and reduction of lipid accumulation and peroxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981870"}
{"pmid": "20981880", "title": "A matrix solid-phase dispersion-gel permeation chromatography-programmed temperature vaporisation-GC-MS procedure for the analysis of polycyclic aromatic hydrocarbons in mussel samples.", "content": "A matrix solid-phase dispersion-gel permeation chromatography-programmed temperature vaporisation-GC-MS procedure for the analysis of polycyclic aromatic hydrocarbons in mussel samples. A simultaneous matrix solid-phase dispersion extraction-gel permeation chromatography cleanup with programmed temperature vaporisation GC-MS determination is proposed for the analysis of parent and alkylated polycyclic aromatic hydrocarbons (PAHs) in mussel samples. The parameters affecting the extraction and elution efficiency were studied. Final conditions were: 0.5 g of mussel sample, 0.5 g diatomaceous earth as dispersant; and 4 g of Bio-Beads S-X3 for the gel permeation chromatography. Ethyl acetate/hexane (1:1, v/v) was selected for the elimination of the lipid fraction and the elution of PAHs. The detection and quantification limits achieved with this procedure were between 0.01 μg/kg and 0.67 μg/kg and 0.02 μg/kg and 1.93 μg/kg, respectively. The linearity of the method ranged between 5 μg/kg and 1000 μg/kg for most of the studied PAHs. The method was validated by the analysis of mussel tissue reference material (SRM 2977). The repeatability, intermediate precision and accuracy of the method obtained are in excellent agreement with the certified values. The proposed method is simple, precise and robust; no special instruments or costly equipment are required, and a reduction in the total time of analysis, sample handling and solvent consumption is achieved in comparison with classic procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981880"}
{"pmid": "20981881", "title": "Molecular-imprinted polymer extraction combined with dispersive liquid-liquid micro-extractionfor ultra-preconcentration of mononitrotoluene.", "content": "Molecular-imprinted polymer extraction combined with dispersive liquid-liquid micro-extractionfor ultra-preconcentration of mononitrotoluene. Molecular-imprinted polymer (MIP) combined with dispersive liquid-liquid micro-extraction (DLLME) were developed for ultra-preconcentration and determination of mononitrotoluenes in wastewater samples using gas chromatography-flame ionization detector. MIP was synthesized by copolymerization of methacrylic acid-ethylene glycole dimethacrylate-2,2-azobisisobutyronitrile as the initiator that imprinted with 3-nitrotoluene as the template molecule. Effects of several factors, such as type and volume of eluent, adsorption, and desorption times of the analyte on the polymer, and breakthrough volume were investigated. Optimization of 3-nitrotoluene extraction from MIP was studied forward followed by DLLME. Preconcentration factor of MIP-DLLME method was about 2800 under the optimum conditions. The LOD of the proposed method was 0.02 μg/L and a linear dynamic range in the range of 0.04-20 μg/L was obtained. The performance of the present method was evaluated for extraction and determination of nitrotoluene compounds in wastewater samples in the range of microgram per liter and satisfactory results were achieved (RSD<13%).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981881"}
{"pmid": "20981875", "title": "Absent gallbladder on fetal ultrasound: prenatal findings and postnatal outcome.", "content": "Absent gallbladder on fetal ultrasound: prenatal findings and postnatal outcome. Fetal gallbladder non-visualization on prenatal ultrasound in the second trimester is uncommon and in most cases the gallbladder is detected eventually. Associations of gallbladder non-visualization with cystic fibrosis, aneuploidy, agenesis of the gallbladder and biliary atresia have been reported. We present our experience and review the literature. During the study period from January 2004 to June 2009 we collected prospectively cases of non-visualization of the fetal gallbladder in the second trimester. In each case the fetus was evaluated by two examiners on at least two occasions, at least a week apart. Cases with no additional sonographic malformations were designated as isolated. Further evaluation included follow-up scans and a meticulous search for fetal anomalies. All patients were offered genetic consultation. Cystic fibrosis testing, amniocentesis for karyotyping and analysis of fetal digestive enzymes in the amniotic fluid were offered. We collected 21 cases of non-visualization of the fetal gallbladder, 16 of which were isolated and five of which had additional malformations. In four of these five, the associated anomalies were severe and the pregnancies were terminated for aneuploidy (two cases of trisomy 18 and one triploidy) or for the severity of the associated anomalies. Associated anomalies included left isomerism with complex cardiac anomaly and intrauterine growth restriction with multisystem anomalies. The fifth fetus had interrupted inferior vena cava with azygos continuation without other anomalies and the child was alive and well at the age of 4 years. In 15 of the 16 isolated cases, antenatal and postnatal development were normal at the last follow-up, ranging from 4 months to 2.5 years. One case of cystic fibrosis was diagnosed prenatally and this pregnancy was terminated. There were no diagnoses of abnormal karyotype or biliary atresia among cases of isolated non-visualization of the gallbladder. When prenatal non-visualization of the fetal gallbladder is associated with other severe malformation, aneuploidy should be suspected. When it is isolated, if cystic fibrosis is ruled out, the outcome is good.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981875"}
{"pmid": "20981882", "title": "Integration of normal phase liquid chromatography with supercritical fluid chromatography for analysis of fruiting bodies of Ganoderma lucidum.", "content": "Integration of normal phase liquid chromatography with supercritical fluid chromatography for analysis of fruiting bodies of Ganoderma lucidum. In this study, a comprehensive 2-D chromatography was constructed, consisting of normal phase LC (NPLC) with a CN column as the first dimension, and supercritical fluid chromatography (SFC), with a Merck Chromolith Flash C(18) column as the second dimension, which were connected by a 10-port, dual-position valve controlled automatically by a self-designed software. Such platform was applied into the analysis of the fruiting bodies of Ganoderma lucidum, a traditional Chinese medicine, and within 2 h analysis, the obtained peak capacity of the 2-D-NPLC-SFC system was about 350, obviously higher than that of each dimension. These results demonstrate that 2-D-NPLC-SFC is not only of good orthogonality, but also of high throughput for the analysis of complex samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981882"}
{"pmid": "20981883", "title": "Separation of parent homopolymers from diblock copolymers by liquid chromatography under limiting conditions of desorption 4. Role of eluent and temperature.", "content": "Separation of parent homopolymers from diblock copolymers by liquid chromatography under limiting conditions of desorption 4. Role of eluent and temperature. Liquid chromatography under limiting conditions of desorption (LC LCD) enables fast, base-line discrimination of both parent homopolymers from various diblock copolymers in one single step. The low molecular admixtures are fully separated, as well. General rules are discussed in detail for selection of mobile phases and temperature applied in LC LCD of block copolymers. Typical practical separation examples are presented. It is shown that both the composition of the well-selected LC LCD mobile phase and the temperature of experiment may vary in a broad range without affecting the basics of method. This implies that the method is robust and user friendly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981883"}
{"pmid": "20981885", "title": "Commentary on \"Secondary use of electronic health record data: spontaneous triggered adverse drug event reporting\" by Linder et al.", "content": "Commentary on \"Secondary use of electronic health record data: spontaneous triggered adverse drug event reporting\" by Linder et al.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981885"}
{"pmid": "20981888", "title": "A graph-based algorithm for mining multi-level patterns in genomic data.", "content": "A graph-based algorithm for mining multi-level patterns in genomic data. Comparative genomics is concerned with the study of genome structure and function of different species. It can provide useful information for the derivation of evolutionary and functional relationships between genomes. Previous work on genome comparison focuses mainly on comparing the entire genomes for visualization without further analysis. As many interesting patterns may exist between genomes and may lead to the discovering of functional gene segments (groups of genes), we propose an algorithm called Multi-Level Genome Comparison Algorithm (MGC) that can be used to facilitate the analysis of genomes at multi-levels during the comparison process to discover sequential and regional consistency in gene segments. Different genomes may have common sub-sequences that differ from each other due to mutations, lateral gene transfers, gene rearrangements, etc., and these sub-sequences are usually not easily identified. Not all the genes can have a perfect one-to-one matching with each other. It is quite possible for one-to-many or many-to-many ambiguous relationships to exist between them. To perform the tasks effectively, MGC takes such ambiguity into consideration during genome comparison by representing genomes in a graph and then make use of a graph mining algorithm called the Multi-Level Attributed Graph Mining Algorithm (MAGMA) to build a hierarchical multi-level graph structure to facilitate genome comparison. To determine the effectiveness of these proposed algorithms, experiments were performed using intra- and inter-species of Microbial genomes. The results show that the proposed algorithms are able to discover multiple level matching patterns that show the similarities and dissimilarities among different genomes, in addition to confirming the specific role of the genes in the genomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981888"}
{"pmid": "20981871", "title": "Quantitative analysis of major dibenzocyclooctane lignans in Schisandrae fructus by online TLC-DART-MS.", "content": "Quantitative analysis of major dibenzocyclooctane lignans in Schisandrae fructus by online TLC-DART-MS. Direct analysis in real time (DART) ion source is a powerful ionising technique for the quick and easy detection of various organic molecules without any sample preparation steps, but the lack of quantitation capacity limits its extensive use in the field of phytochemical analysis. To improvise a new system which utilize DART-MS as a hyphenated detector for quantitation. A total extract of Schisandra chinensis fruit was analyzed on a TLC plate and three major lignan compounds were quantitated by three different methods of UV densitometry, TLC-DART-MS and HPLC-UV to compare the efficiency of each method. To introduce the TLC plate into the DART ion source at a constant velocity, a syringe pump was employed. The DART-MS total ion current chromatogram was recorded for the entire TLC plate. The concentration of each lignan compound was calculated from the calibration curve established with standard compound. Gomisin A, gomisin N and schisandrin were well separated on a silica-coated TLC plate and the specific ion current chromatograms were successfully acquired from the TLC-DART-MS system. The TLC-DART-MS system for the quantitation of natural products showed better linearity and specificity than TLC densitometry, and consumed less time and solvent than conventional HPLC method. A hyphenated system for the quantitation of phytochemicals from crude herbal drugs was successfully established. This system was shown to have a powerful analytical capacity for the prompt and efficient quantitation of natural products from crude drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981871"}
{"pmid": "20981889", "title": "Relative von Neumann entropy for evaluating amino acid conservation.", "content": "Relative von Neumann entropy for evaluating amino acid conservation. The Shannon entropy is a common way of measuring conservation of sites in multiple sequence alignments, and has also been extended with the relative Shannon entropy to account for background frequencies. The von Neumann entropy is another extension of the Shannon entropy, adapted from quantum mechanics in order to account for amino acid similarities. However, there is yet no relative von Neumann entropy defined for sequence analysis. We introduce a new definition of the von Neumann entropy for use in sequence analysis, which we found to perform better than the previous definition. We also introduce the relative von Neumann entropy and a way of parametrizing this in order to obtain the Shannon entropy, the relative Shannon entropy and the von Neumann entropy at special parameter values. We performed an exhaustive search of this parameter space and found better predictions of catalytic sites compared to any of the previously used entropies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981889"}
{"pmid": "20981890", "title": "FuzzyART neural network for protein classification.", "content": "FuzzyART neural network for protein classification. One of the major research directions in bioinformatics is that of predicting the protein superfamily in large databases and classifying a given set of protein domains into superfamilies. The classification reflects the structural, evolutionary and functional relatedness. These relationships are embodied in hierarchical classification such as Structural Classification of Protein (SCOP), which is manually curated. Such classification is essential for the structural and functional analysis of proteins. Yet, a large number of proteins remain unclassified. We have proposed an unsupervised machine-learning FuzzyART neural network algorithm to classify a given set of proteins into SCOP superfamilies. The proposed method is fast learning and uses an atypical non-linear pattern recognition technique. In this approach, we have constructed a similarity matrix from p-values of BLAST all-against-all, trained the network with FuzzyART unsupervised learning algorithm using the similarity matrix as input vectors and finally the trained network offers SCOP superfamily level classification. In this experiment, we have evaluated the performance of our method with existing techniques on six different datasets. We have shown that the trained network is able to classify a given similarity matrix of a set of sequences into SCOP superfamilies at high classification accuracy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981890"}
{"pmid": "20981891", "title": "Computational gene knockout reveals transdisease-transgene association structure.", "content": "Computational gene knockout reveals transdisease-transgene association structure. Genome-wide association studies for a variety of diseases are identifying increasing numbers of candidate genes. Now we are confronted with the fact that some genes are common candidates across diseases. Thus there is a strong need to develop a hypothesis formulation methodology to comprehend multifaceted associations between genes and diseases. We have developed a computational method for building transdisease-transgene association structure. By introducing the basic rationale underlying the gene knockout approach as an information processing procedure to a network constructed on the basis of hyperlinks between disease and gene pages listed in the Online Mendelian Inheritance in Man (OMIM) database, relations of genes with diseases are computationally quantified. We did successively eliminate gene pages (called \"computational gene knockout\" in this paper) expected to contribute to metabolic syndrome, and catalogued each association with various disease pages. We thereby apply a co-clustering method to the gene-disease relations to obtain an association structure by classifying diseases and genes simultaneously. Observing an association structure between over 100 diseases and their related genes, we then found that the structure revealed gene classes that were commonly associated with diseases as well as gene classes that were selectively associated with a specific disease class.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981891"}
{"pmid": "20981892", "title": "Protein secondary structure prediction using NMR chemical shift data.", "content": "Protein secondary structure prediction using NMR chemical shift data. Accurate determination of protein secondary structure from the chemical shift information is a key step for NMR tertiary structure determination. Relatively few work has been done on this subject. There needs to be a systematic investigation of algorithms that are (a) robust for large datasets; (b) easily extendable to (the dynamic) new databases; and (c) approaching to the limit of accuracy. We introduce new approaches using k-nearest neighbor algorithm to do the basic prediction and use the BCJR algorithm to smooth the predictions and combine different predictions from chemical shifts and based on sequence information only. Our new system, SUCCES, improves the accuracy of all existing methods on a large dataset of 805 proteins (at 86% Q(3) accuracy and at 92.6% accuracy when the boundary residues are ignored), and it is easily extendable to any new dataset without requiring any new training. The software is publicly available at http://monod.uwaterloo.ca/nmr/succes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981892"}
{"pmid": "20981893", "title": "Analysis of qPCR data by converting exponentially related Ct values into linearly related X0 values.", "content": "Analysis of qPCR data by converting exponentially related Ct values into linearly related X0 values. A common method for calculating results from qPCR experiments is the comparative Ct method, also called the 2(-ΔΔCt) method. However, several assumptions are included in the 2(-ΔΔCt) method and standard statistical analyses are not directly applicable. Here, we describe a different method, the X(0) method, for result calculations and statistical analysis from qPCR experiments. The X(0) method differs from the 2(-ΔΔCt) method by introducing a conversion of the exponentially related Ct values into linearly related X(0) values, which represent the amount of starting material in a qPCR experiment. Results calculated by the X(0) method are illustrated for qPCR experiments with technical and biological replicates, including procedures to calculate standard deviations. Incorporation of primer efficiencies in calculations by the X(0) method is also described. Altogether, the X(0) method constitutes a very simple and accurate alternative to the 2(-ΔΔCt) method for result calculations from qPCR data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981893"}
{"pmid": "20981894", "title": "Improving the inter-corpora compatibility for protein annotations.", "content": "Improving the inter-corpora compatibility for protein annotations. Although there are several corpora with protein annotation, incompatibility between the annotations in different corpora remains a problem that hinders the progress of automatic recognition of protein names in biomedical literature. Here, we report on our efforts to find a solution to the incompatibility issue, and to improve the compatibility between two representative protein-annotated corpora: the GENIA corpus and the GENETAG corpus. In a comparative study, we improve our insight into the two corpora, and a series of experimental results show that most of the incompatibility can be removed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981894"}
{"pmid": "20981895", "title": "A re-evaluation of biomedical named entity-term relations.", "content": "A re-evaluation of biomedical named entity-term relations. Text mining can support the interpretation of the enormous quantity of textual data produced in biomedical field. Recent developments in biomedical text mining include advances in the reliability of the recognition of named entities (NEs) such as specific genes and proteins, as well as movement toward richer representations of the associations of NEs. We argue that this shift in representation should be accompanied by the adoption of a more detailed model of the relations holding between NEs and other relevant domain terms. As a step toward this goal, we study NE-term relations with the aim of defining a detailed, broadly applicable set of relation types based on accepted domain standard concepts for use in corpus annotation and domain information extraction approaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981895"}
{"pmid": "20981897", "title": "Observations upon the form and relations of the maternal and fetal vessels in the placenta of the sheep.", "content": "Observations upon the form and relations of the maternal and fetal vessels in the placenta of the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981897"}
{"pmid": "20981896", "title": "Placentation and angiogenesis in the amnion of a baboon (Papio papio).", "content": "Placentation and angiogenesis in the amnion of a baboon (Papio papio).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981896"}
{"pmid": "20981898", "title": "The development and histology of pituitary concretions in man.", "content": "The development and histology of pituitary concretions in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981898"}
{"pmid": "20981899", "title": "Scent glands of the short-tailed shrew.", "content": "Scent glands of the short-tailed shrew.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981899"}
{"pmid": "20981900", "title": "Response to pituitary growth hormone and thyroxin of the tibias of hypophysectomized rats after long postoperative intervals.", "content": "Response to pituitary growth hormone and thyroxin of the tibias of hypophysectomized rats after long postoperative intervals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981900"}
{"pmid": "20981902", "title": "Changes in the blood of the dog with age.", "content": "Changes in the blood of the dog with age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981902"}
{"pmid": "20981903", "title": "Visual factors in the design of military aircraft.", "content": "Visual factors in the design of military aircraft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981903"}
{"pmid": "20981901", "title": "Bilateral superior vena cavae.", "content": "Bilateral superior vena cavae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981901"}
{"pmid": "20981904", "title": "The effect of ammonium chloride on altitude tolerance.", "content": "The effect of ammonium chloride on altitude tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981904"}
{"pmid": "20981906", "title": "Thermocouples and the measurement of body temperatures in the laboratory and in flight.", "content": "Thermocouples and the measurement of body temperatures in the laboratory and in flight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981906"}
{"pmid": "20981907", "title": "Selection of men for aeronautical training based on susceptibility to motion sickness.", "content": "Selection of men for aeronautical training based on susceptibility to motion sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981907"}
{"pmid": "20981905", "title": "Physical exertion in the heat: some notes on its physiology and hygiene.", "content": "Physical exertion in the heat: some notes on its physiology and hygiene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981905"}
{"pmid": "20981908", "title": "The effects of hypocapnia on performance.", "content": "The effects of hypocapnia on performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981908"}
{"pmid": "20981909", "title": "A method for the continuous analysis of alveolar air.", "content": "A method for the continuous analysis of alveolar air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981909"}
{"pmid": "20981910", "title": "The high altitude training program for fighter pilots.", "content": "The high altitude training program for fighter pilots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981910"}
{"pmid": "20981911", "title": "Diseases and defects in aircrew trainees; gastro-intestinal system, genito-urinary system.", "content": "Diseases and defects in aircrew trainees; gastro-intestinal system, genito-urinary system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981911"}
{"pmid": "20981912", "title": "Recent advances in airplane spraying of DDT for insect control.", "content": "Recent advances in airplane spraying of DDT for insect control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981912"}
{"pmid": "20981913", "title": "The covariance analysis of multiple classification tables with unequal subclass numbers.", "content": "The covariance analysis of multiple classification tables with unequal subclass numbers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981913"}
{"pmid": "20981914", "title": "Statistical methods in cereal chemistry.", "content": "Statistical methods in cereal chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981914"}
{"pmid": "20981915", "title": "Incomplete-block design adapted to paired tests of mosquito repellents.", "content": "Incomplete-block design adapted to paired tests of mosquito repellents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981915"}
{"pmid": "20981916", "title": "Effect of experimental malaria on the electrophoretic pattern of the serum proteins of normal young men.", "content": "Effect of experimental malaria on the electrophoretic pattern of the serum proteins of normal young men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981916"}
{"pmid": "20981917", "title": "Relation of fasting ketosis to the protein of the preceding diet.", "content": "Relation of fasting ketosis to the protein of the preceding diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981917"}
{"pmid": "20981918", "title": "Studies on the metabolism of 2-acetylaminofluorene in rats.", "content": "Studies on the metabolism of 2-acetylaminofluorene in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981918"}
{"pmid": "20981919", "title": "Central nervous system effects of anticholinergic agents.", "content": "Central nervous system effects of anticholinergic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981919"}
{"pmid": "20981920", "title": "The application of a graded type of response technique for the bio-assay of pituitary extract (posterior lobe).", "content": "The application of a graded type of response technique for the bio-assay of pituitary extract (posterior lobe).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981920"}
{"pmid": "20981921", "title": "The action of fumariaceous alkaloids.", "content": "The action of fumariaceous alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981921"}
{"pmid": "20981923", "title": "Concentration technique for detection of trophozoites of human malaria.", "content": "Concentration technique for detection of trophozoites of human malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981923"}
{"pmid": "20981922", "title": "The pharmacology of a new series of choline salts.", "content": "The pharmacology of a new series of choline salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981922"}
{"pmid": "20981924", "title": "The effect of methyl xanthines on urea excretion in rabbits.", "content": "The effect of methyl xanthines on urea excretion in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981924"}
{"pmid": "20981925", "title": "The blood pressure lowering effect of local anesthetics used for injection.", "content": "The blood pressure lowering effect of local anesthetics used for injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981925"}
{"pmid": "20981926", "title": "Liver injury and its influence upon the acetylcholine splitting activity of rat and dog.", "content": "Liver injury and its influence upon the acetylcholine splitting activity of rat and dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981926"}
{"pmid": "20981927", "title": "Use of the latent period in studies on the agent of chicken tumor I.", "content": "Use of the latent period in studies on the agent of chicken tumor I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981927"}
{"pmid": "20981929", "title": "Pharmacology of fluoroacetate.", "content": "Pharmacology of fluoroacetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981929"}
{"pmid": "20981928", "title": "Electrocardiographic changes of rats, dogs and monkeys receiving toxic doses of plasmochin and the acid-labile phosphate content of the rat's myocardium.", "content": "Electrocardiographic changes of rats, dogs and monkeys receiving toxic doses of plasmochin and the acid-labile phosphate content of the rat's myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981928"}
{"pmid": "20981930", "title": "The effects of di-isopropyl fluorophosphate upon normal subjects and patients with myasthenia gravis.", "content": "The effects of di-isopropyl fluorophosphate upon normal subjects and patients with myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981930"}
{"pmid": "20981931", "title": "Comparison of a chemical and a biological method for the assay of a purified digitalis preparation.", "content": "Comparison of a chemical and a biological method for the assay of a purified digitalis preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981931"}
{"pmid": "20981932", "title": "Failure of o- or p-mononitrophenol to produce cataract.", "content": "Failure of o- or p-mononitrophenol to produce cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981932"}
{"pmid": "20981933", "title": "The effects of body-gassing with mustard vapor on the carbohydrate metabolism of dogs.", "content": "The effects of body-gassing with mustard vapor on the carbohydrate metabolism of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981933"}
{"pmid": "20981935", "title": "A comparison of the effects of streptomycin on the nutrition of the rat and the mouse.", "content": "A comparison of the effects of streptomycin on the nutrition of the rat and the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981935"}
{"pmid": "20981934", "title": "Pamaquin; occurrence of hemolytic anemias.", "content": "Pamaquin; occurrence of hemolytic anemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981934"}
{"pmid": "20981936", "title": "The analgesic action of the racemates of I-amino-I-phthalidylpropane hydrochloride.", "content": "The analgesic action of the racemates of I-amino-I-phthalidylpropane hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981936"}
{"pmid": "20981937", "title": "The diuretic-antidiuretic actions of posterior pituitary and sodium chloride.", "content": "The diuretic-antidiuretic actions of posterior pituitary and sodium chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981937"}
{"pmid": "20981938", "title": "Studies on the anticonvulsant properties of diphenylhydantoin.", "content": "Studies on the anticonvulsant properties of diphenylhydantoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981938"}
{"pmid": "20981939", "title": "Loss of potency of commercial insulin stored at room temperature.", "content": "Loss of potency of commercial insulin stored at room temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981939"}
{"pmid": "20981940", "title": "Effects of senecionine on the hamster and monkey.", "content": "Effects of senecionine on the hamster and monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981940"}
{"pmid": "20981941", "title": "Electrocardiographic changes in pericarditis associated with uremia.", "content": "Electrocardiographic changes in pericarditis associated with uremia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981941"}
{"pmid": "20981942", "title": "Paroxysmal ventricular tachycardia.", "content": "Paroxysmal ventricular tachycardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981942"}
{"pmid": "20981943", "title": "Electrocardiographic studies during and after pneumococcus pneumonia.", "content": "Electrocardiographic studies during and after pneumococcus pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981943"}
{"pmid": "20981944", "title": "Calcification of the mitral valve.", "content": "Calcification of the mitral valve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981944"}
{"pmid": "20981946", "title": "The peripheral blood flow and rectal and skin temperatures in hypertension.", "content": "The peripheral blood flow and rectal and skin temperatures in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981946"}
{"pmid": "20981945", "title": "Studies on the pathogenesis of pulmonary edema following bilateral vagotomy.", "content": "Studies on the pathogenesis of pulmonary edema following bilateral vagotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981945"}
{"pmid": "20981947", "title": "An evaluation of the use of multiple versus single precordial leads, in conjunction with the three limb leads, for practical clinical electrocardiography.", "content": "An evaluation of the use of multiple versus single precordial leads, in conjunction with the three limb leads, for practical clinical electrocardiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981947"}
{"pmid": "20981948", "title": "Abnormal electrocardiogram following recovery from paroxysmal tachycardia.", "content": "Abnormal electrocardiogram following recovery from paroxysmal tachycardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981948"}
{"pmid": "20981949", "title": "Subacute bacterial endocarditis successfully treated with penicillin; report of a case.", "content": "Subacute bacterial endocarditis successfully treated with penicillin; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981949"}
{"pmid": "20981957", "title": "Ranula.", "content": "Ranula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981957"}
{"pmid": "20981958", "title": "The maxillary labial fraenum in the school health service.", "content": "The maxillary labial fraenum in the school health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981958"}
{"pmid": "20981959", "title": "Trilene auto analgesia in dentistry.", "content": "Trilene auto analgesia in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981959"}
{"pmid": "20981960", "title": "The production of dental alloys and substitutes for plaster of Paris in Changi P.O.W. Camp, Singapore.", "content": "The production of dental alloys and substitutes for plaster of Paris in Changi P.O.W. Camp, Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981960"}
{"pmid": "20981961", "title": "Observations on the oral condition of Indian soldiers.", "content": "Observations on the oral condition of Indian soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981961"}
{"pmid": "20981962", "title": "The fluorine-dental caries relationship in general with particular association with Colorado Springs.", "content": "The fluorine-dental caries relationship in general with particular association with Colorado Springs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981962"}
{"pmid": "20981963", "title": "The use of x-ray in the diagnosis of systemic disease.", "content": "The use of x-ray in the diagnosis of systemic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981963"}
{"pmid": "20981964", "title": "Some legal aspects of the ownership of roentgenograms.", "content": "Some legal aspects of the ownership of roentgenograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981964"}
{"pmid": "20981965", "title": "The effect of malnutrition on calcification and growth of the teeth during childhood.", "content": "The effect of malnutrition on calcification and growth of the teeth during childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981965"}
{"pmid": "20981966", "title": "Comparison of thermal and hygroscopic casting technics.", "content": "Comparison of thermal and hygroscopic casting technics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981966"}
{"pmid": "20981967", "title": "Go modern with preventive dentistry.", "content": "Go modern with preventive dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981967"}
{"pmid": "20981969", "title": "The problem of the upper partial denture.", "content": "The problem of the upper partial denture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981969"}
{"pmid": "20981968", "title": "Acrylic resin jacket crown construction.", "content": "Acrylic resin jacket crown construction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981968"}
{"pmid": "20981970", "title": "Radiographs in dentistry for children.", "content": "Radiographs in dentistry for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981970"}
{"pmid": "20981972", "title": "Immediate denture construction.", "content": "Immediate denture construction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981972"}
{"pmid": "20981971", "title": "Pulpotomy technic.", "content": "Pulpotomy technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981971"}
{"pmid": "20981973", "title": "IMMEDIATE dentures.", "content": "IMMEDIATE dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981973"}
{"pmid": "20981974", "title": "The dentist looks at cancer of the lip.", "content": "The dentist looks at cancer of the lip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20981974"}
{"pmid": "20982069", "title": "The comparative effect of human chorionic and equine gonadotrophins on the rate of ovarian growth.", "content": "The comparative effect of human chorionic and equine gonadotrophins on the rate of ovarian growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982069"}
{"pmid": "20982071", "title": "The influence of estrogens on the crystal structure of bone as revealed by x-ray diffraction studies on the femora of mice.", "content": "The influence of estrogens on the crystal structure of bone as revealed by x-ray diffraction studies on the femora of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982071"}
{"pmid": "20982070", "title": "Tolerance of normal, of thyroidectomized, and of thiourea or thiouracil treated dogs to oral desiccated thyroid and to intravenous thyroxine.", "content": "Tolerance of normal, of thyroidectomized, and of thiourea or thiouracil treated dogs to oral desiccated thyroid and to intravenous thyroxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982070"}
{"pmid": "20982072", "title": "The effects of alloxan diabetes on the in-vitro oxidation of substrates by rat tissues.", "content": "The effects of alloxan diabetes on the in-vitro oxidation of substrates by rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982072"}
{"pmid": "20982073", "title": "The passage of endogenous estrogen across the parabiotic union in rats.", "content": "The passage of endogenous estrogen across the parabiotic union in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982073"}
{"pmid": "20982074", "title": "Acid-base equilibrium in relation to the menstrual cycle.", "content": "Acid-base equilibrium in relation to the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982074"}
{"pmid": "20982075", "title": "A note on the absence of androgen from a diet of natural foods.", "content": "A note on the absence of androgen from a diet of natural foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982075"}
{"pmid": "20982076", "title": "Enterohepatic circulation of oestrogens.", "content": "Enterohepatic circulation of oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982076"}
{"pmid": "20982077", "title": "Some factors affecting the absorption rate of subcutaneously implanted hormone tablets.", "content": "Some factors affecting the absorption rate of subcutaneously implanted hormone tablets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982077"}
{"pmid": "20982078", "title": "Some factors affecting absorption from implanted tablets.", "content": "Some factors affecting absorption from implanted tablets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982078"}
{"pmid": "20982080", "title": "Logistic dose-response curves: a theoretical approach.", "content": "Logistic dose-response curves: a theoretical approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982080"}
{"pmid": "20982079", "title": "Functional relation between the uterus and the corpus luteum.", "content": "Functional relation between the uterus and the corpus luteum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982079"}
{"pmid": "20982081", "title": "Fertilization of eggs in hypophysectomized rats.", "content": "Fertilization of eggs in hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982081"}
{"pmid": "20982082", "title": "Further observations on the formation of \"ghosts\" in subcutaneously implanted tablets.", "content": "Further observations on the formation of \"ghosts\" in subcutaneously implanted tablets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982082"}
{"pmid": "20982083", "title": "Relation between iodine content and biological activity of thyroid preparations.", "content": "Relation between iodine content and biological activity of thyroid preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982083"}
{"pmid": "20982084", "title": "Gonad stimulation by androgens in hypophysectomized pigeons.", "content": "Gonad stimulation by androgens in hypophysectomized pigeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982084"}
{"pmid": "20982092", "title": "New Zealand blood-type distributions: preliminary investigations.", "content": "New Zealand blood-type distributions: preliminary investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982092"}
{"pmid": "20982093", "title": "Genetic theories of Rh blood types.", "content": "Genetic theories of Rh blood types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982093"}
{"pmid": "20982094", "title": "The inheritance of allelomorphs of the Rh gene in 50 families.", "content": "The inheritance of allelomorphs of the Rh gene in 50 families.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982094"}
{"pmid": "20982095", "title": "Filial and fraternal correlations in successive generations.", "content": "Filial and fraternal correlations in successive generations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982095"}
{"pmid": "20982096", "title": "A further note on the sib-pair linkage method.", "content": "A further note on the sib-pair linkage method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982096"}
{"pmid": "20982097", "title": "Crossing-over in a pedigree containing haemophilic and colour-blind individuals.", "content": "Crossing-over in a pedigree containing haemophilic and colour-blind individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982097"}
{"pmid": "20982099", "title": "The trend of national intelligence.", "content": "The trend of national intelligence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982099"}
{"pmid": "20982098", "title": "An investigation of 171 possible linkage relationships in man.", "content": "An investigation of 171 possible linkage relationships in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982098"}
{"pmid": "20982100", "title": "Some problems of reproductive physiology.", "content": "Some problems of reproductive physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982100"}
{"pmid": "20982101", "title": "Positive eugenics; a proposal.", "content": "Positive eugenics; a proposal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982101"}
{"pmid": "20982102", "title": "An investigation into assortative mating.", "content": "An investigation into assortative mating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982102"}
{"pmid": "20982103", "title": "Courtship and mating in an urban community.", "content": "Courtship and mating in an urban community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982103"}
{"pmid": "20982104", "title": "Birth-rate in Holland.", "content": "Birth-rate in Holland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982104"}
{"pmid": "20982111", "title": "The control of infection in obstetrics.", "content": "The control of infection in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982111"}
{"pmid": "20982112", "title": "The value of antenatal radiological pelvimetry.", "content": "The value of antenatal radiological pelvimetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982112"}
{"pmid": "20982113", "title": "Combined anterior pituitary necrosis and bilateral cortical necrosis of the kidneys, following concealed accidental haemorrhage.", "content": "Combined anterior pituitary necrosis and bilateral cortical necrosis of the kidneys, following concealed accidental haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982113"}
{"pmid": "20982114", "title": "Infertility in women.", "content": "Infertility in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982114"}
{"pmid": "20982115", "title": "Male infertility.", "content": "Male infertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982115"}
{"pmid": "20982116", "title": "Acute renal failure complicating abortion.", "content": "Acute renal failure complicating abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982116"}
{"pmid": "20982117", "title": "The mother in industry.", "content": "The mother in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982117"}
{"pmid": "20982118", "title": "A case of aplastic anaemia in pregnancy.", "content": "A case of aplastic anaemia in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982118"}
{"pmid": "20982119", "title": "A home-made repositor for chronic inversion of the uterus.", "content": "A home-made repositor for chronic inversion of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982119"}
{"pmid": "20982133", "title": "Anesthesia for eye, ear, nose and throat surgery.", "content": "Anesthesia for eye, ear, nose and throat surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982133"}
{"pmid": "20982134", "title": "The place of nitrous oxide-oxygen anesthesia in present day practice of anesthesiology.", "content": "The place of nitrous oxide-oxygen anesthesia in present day practice of anesthesiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982134"}
{"pmid": "20982135", "title": "Pentothal sodium.", "content": "Pentothal sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982135"}
{"pmid": "20982136", "title": "The use of cyclopropane.", "content": "The use of cyclopropane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982136"}
{"pmid": "20982137", "title": "Spinal anesthesia from the patient's viewpoint.", "content": "Spinal anesthesia from the patient's viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982137"}
{"pmid": "20982138", "title": "Homoeopathy and leg ulcers.", "content": "Homoeopathy and leg ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982138"}
{"pmid": "20982139", "title": "The syphilitic remedies.", "content": "The syphilitic remedies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982139"}
{"pmid": "20982140", "title": "A proving of Crocus sativus.", "content": "A proving of Crocus sativus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982140"}
{"pmid": "20982142", "title": "Tuberculinum; some clinical experiences.", "content": "Tuberculinum; some clinical experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982142"}
{"pmid": "20982143", "title": "Sketches of surgical-homeopathic experiences.", "content": "Sketches of surgical-homeopathic experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982143"}
{"pmid": "20982144", "title": "Homeopathy; the true art of healing.", "content": "Homeopathy; the true art of healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982144"}
{"pmid": "20982141", "title": "Homoeopathic therapy in some nerve diseases; tabes dorsalis.", "content": "Homoeopathic therapy in some nerve diseases; tabes dorsalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982141"}
{"pmid": "20982145", "title": "WHAT can a mental hospital do to improve public relations?", "content": "WHAT can a mental hospital do to improve public relations?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982145"}
{"pmid": "20982146", "title": "What type of hospital for the mental patient?", "content": "What type of hospital for the mental patient?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982146"}
{"pmid": "20982151", "title": "Metabolites of 2,4,6-trinitrotoluene (TNT) excreted in the urine of dogs.", "content": "Metabolites of 2,4,6-trinitrotoluene (TNT) excreted in the urine of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982151"}
{"pmid": "20982152", "title": "Summary of twenty-two trinitrotoluene fatalities in World War II.", "content": "Summary of twenty-two trinitrotoluene fatalities in World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982152"}
{"pmid": "20982153", "title": "An experimental evaluation of methionine in the therapy of liver injury from carbon tetrachloride.", "content": "An experimental evaluation of methionine in the therapy of liver injury from carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982153"}
{"pmid": "20982154", "title": "Eight cases of methyl chloride poisoning with three deaths.", "content": "Eight cases of methyl chloride poisoning with three deaths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982154"}
{"pmid": "20982155", "title": "Evaluation of urinary lead excretion for persons at work.", "content": "Evaluation of urinary lead excretion for persons at work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982155"}
{"pmid": "20982156", "title": "Dust control in hematite mining; the effect of wet methods.", "content": "Dust control in hematite mining; the effect of wet methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982156"}
{"pmid": "20982157", "title": "Dust control in hematite mining; the effect of ventilation.", "content": "Dust control in hematite mining; the effect of ventilation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982157"}
{"pmid": "20982159", "title": "Application of military mental hygiene to industry.", "content": "Application of military mental hygiene to industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982159"}
{"pmid": "20982160", "title": "A program of malarial surveillance for the industrial physician.", "content": "A program of malarial surveillance for the industrial physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982160"}
{"pmid": "20982158", "title": "Filter paper collection of cadmium and iron fumes in air.", "content": "Filter paper collection of cadmium and iron fumes in air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982158"}
{"pmid": "20982161", "title": "Aplastic anemia following exposure to trinitrotoluene; report of three cases.", "content": "Aplastic anemia following exposure to trinitrotoluene; report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982161"}
{"pmid": "20982163", "title": "A method for the evaluation of protective ointments.", "content": "A method for the evaluation of protective ointments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982163"}
{"pmid": "20982162", "title": "A clinical test for effort tolerance.", "content": "A clinical test for effort tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982162"}
{"pmid": "20982164", "title": "An outbreak of scabies in stenographers.", "content": "An outbreak of scabies in stenographers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982164"}
{"pmid": "20982166", "title": "Contact dermatitis due to DDT; report of a case.", "content": "Contact dermatitis due to DDT; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982166"}
{"pmid": "20982165", "title": "Arsine poisoning; report of a case.", "content": "Arsine poisoning; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982165"}
{"pmid": "20982169", "title": "Medical research in physical education; some physiological limitations of athletic performances.", "content": "Medical research in physical education; some physiological limitations of athletic performances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982169"}
{"pmid": "20982170", "title": "The use (for cosmetic and biological reasons) of plasmathromboplastin adhesion as a substitute for sutures in thyroid surgery.", "content": "The use (for cosmetic and biological reasons) of plasmathromboplastin adhesion as a substitute for sutures in thyroid surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982170"}
{"pmid": "20982171", "title": "Ascaris-pneumonia; notes on the review on Ascaris lumbricoides.", "content": "Ascaris-pneumonia; notes on the review on Ascaris lumbricoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982171"}
{"pmid": "20982172", "title": "Activation of an originally negative intracutaneous Leishmania-vaccine reaction.", "content": "Activation of an originally negative intracutaneous Leishmania-vaccine reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982172"}
{"pmid": "20982173", "title": "Intramuscular pressure; a critical review.", "content": "Intramuscular pressure; a critical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982173"}
{"pmid": "20982174", "title": "Pulmonic lesions with eosinophilia.", "content": "Pulmonic lesions with eosinophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982174"}
{"pmid": "20982182", "title": "Filariasis in Bundelkhand.", "content": "Filariasis in Bundelkhand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982182"}
{"pmid": "20982183", "title": "Teratoma of testis.", "content": "Teratoma of testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982183"}
{"pmid": "20982184", "title": "Nervous complications of diphtheria.", "content": "Nervous complications of diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982184"}
{"pmid": "20982185", "title": "Infantile hepatic cirrhosis (conditions described as infantile biliary cirrhosis; sub-acute toxic cirrhosis; and infantile liver).", "content": "Infantile hepatic cirrhosis (conditions described as infantile biliary cirrhosis; sub-acute toxic cirrhosis; and infantile liver).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982185"}
{"pmid": "20982186", "title": "Auto-intoxication.", "content": "Auto-intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982186"}
{"pmid": "20982187", "title": "A case of maggots in the nasal cavity.", "content": "A case of maggots in the nasal cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982187"}
{"pmid": "20982189", "title": "Ascariasis.", "content": "Ascariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982189"}
{"pmid": "20982188", "title": "Penicillin in chronic arthritis knee.", "content": "Penicillin in chronic arthritis knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982188"}
{"pmid": "20982190", "title": "Stanno sulphazide and chaulmoogra oil in chronic skin ulcerations.", "content": "Stanno sulphazide and chaulmoogra oil in chronic skin ulcerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982190"}
{"pmid": "20982191", "title": "Results in the treatment of subacute bacterial endocarditis.", "content": "Results in the treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982191"}
{"pmid": "20982192", "title": "Studies on hypertension; effect of lowering the blood pressures of hypertensive patients by high spinal anesthesia on the renal function as measured by inulin and diodrast clearances.", "content": "Studies on hypertension; effect of lowering the blood pressures of hypertensive patients by high spinal anesthesia on the renal function as measured by inulin and diodrast clearances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982192"}
{"pmid": "20982193", "title": "A roentgen ray and clinical study of primary tuberculosis; Vollmer patch test made on 460 patients; positive reactions secured in 115.", "content": "A roentgen ray and clinical study of primary tuberculosis; Vollmer patch test made on 460 patients; positive reactions secured in 115.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982193"}
{"pmid": "20982194", "title": "Electrocardiogram in toxemias of pregnancy.", "content": "Electrocardiogram in toxemias of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982194"}
{"pmid": "20982195", "title": "Prothrombin level of peripheral blood and sternal marrow.", "content": "Prothrombin level of peripheral blood and sternal marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982195"}
{"pmid": "20982196", "title": "Syphilis; a review of the recent literature.", "content": "Syphilis; a review of the recent literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982196"}
{"pmid": "20982205", "title": "Weil's disease occurrence among workers in Welsh and Scottish coal-mines.", "content": "Weil's disease occurrence among workers in Welsh and Scottish coal-mines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982205"}
{"pmid": "20982204", "title": "Economic status and the haemoglobin level of children of men in the fighting services and of civilians.", "content": "Economic status and the haemoglobin level of children of men in the fighting services and of civilians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982204"}
{"pmid": "20982206", "title": "Insulin shock treatment of bronchial asthma.", "content": "Insulin shock treatment of bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982206"}
{"pmid": "20982207", "title": "Carcinoma of the lip and its treatment by radium (1928-1944).", "content": "Carcinoma of the lip and its treatment by radium (1928-1944).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982207"}
{"pmid": "20982208", "title": "Pyloric stenosis: selective medical and surgical treatment; 50 successive cases without a death or failed medical treatment.", "content": "Pyloric stenosis: selective medical and surgical treatment; 50 successive cases without a death or failed medical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982208"}
{"pmid": "20982209", "title": "Diphtheritic encephalomyelitis.", "content": "Diphtheritic encephalomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982209"}
{"pmid": "20982210", "title": "A case of dysphagia in a woman 78 cured by tonsillectomy.", "content": "A case of dysphagia in a woman 78 cured by tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982210"}
{"pmid": "20982211", "title": "Iritis in the rheumatic affections.", "content": "Iritis in the rheumatic affections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982211"}
{"pmid": "20982212", "title": "Prevention of transfusion reactions due to Rh factors.", "content": "Prevention of transfusion reactions due to Rh factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982212"}
{"pmid": "20982214", "title": "MEDICAL evidence in pension claims.", "content": "MEDICAL evidence in pension claims.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982214"}
{"pmid": "20982213", "title": "HEALTH Service Bill.", "content": "HEALTH Service Bill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982213"}
{"pmid": "20982215", "title": "The importance to the medical practitioner of a knowledge of heredity in diseases.", "content": "The importance to the medical practitioner of a knowledge of heredity in diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982215"}
{"pmid": "20982232", "title": "Atabrine studies in the field; the relation of serum atabrine level to breakthrough of previously contracted vivax malaria.", "content": "Atabrine studies in the field; the relation of serum atabrine level to breakthrough of previously contracted vivax malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982232"}
{"pmid": "20982233", "title": "Studies on convalescence; nitrogen and mitral balances during starvation and graduated feeding in healthy young males at bed rest.", "content": "Studies on convalescence; nitrogen and mitral balances during starvation and graduated feeding in healthy young males at bed rest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982233"}
{"pmid": "20982234", "title": "Studies on the pharmacology of DDT (2,2 bis-para-chlorophenyl-l,l,l,trichloroethane); the chronic toxicity of DDT in the dog.", "content": "Studies on the pharmacology of DDT (2,2 bis-para-chlorophenyl-l,l,l,trichloroethane); the chronic toxicity of DDT in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982234"}
{"pmid": "20982236", "title": "Biochemical changes associated with the activity of the adrenal cortex.", "content": "Biochemical changes associated with the activity of the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982236"}
{"pmid": "20982235", "title": "Experiences in the psychotherapy of obsessive-schizophrenic personalities.", "content": "Experiences in the psychotherapy of obsessive-schizophrenic personalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982235"}
{"pmid": "20982237", "title": "Pituitary-adrenal cortical control of normal and immune globulin release from lymphocytes.", "content": "Pituitary-adrenal cortical control of normal and immune globulin release from lymphocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982237"}
{"pmid": "20982238", "title": "Laboratory aids in anemia.", "content": "Laboratory aids in anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982238"}
{"pmid": "20982239", "title": "Factors common to surgical lesions of the biliary tract.", "content": "Factors common to surgical lesions of the biliary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982239"}
{"pmid": "20982240", "title": "The surgical treatment of acute cholecystitis.", "content": "The surgical treatment of acute cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982240"}
{"pmid": "20982241", "title": "Treatment of chronic cholecystitis, with and without stone; indications and contraindications for choledochostomy.", "content": "Treatment of chronic cholecystitis, with and without stone; indications and contraindications for choledochostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982241"}
{"pmid": "20982242", "title": "The repair of strictures of the common and hepatic bile ducts.", "content": "The repair of strictures of the common and hepatic bile ducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982242"}
{"pmid": "20982243", "title": "The treatment of seasonal and non-seasonal hyperesthetic rhinitis with anthallan.", "content": "The treatment of seasonal and non-seasonal hyperesthetic rhinitis with anthallan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982243"}
{"pmid": "20982244", "title": "Primary carcinoma of the lung, including a clinico pathologic report of 45 cases at the University Hospital from 1934 to 1946.", "content": "Primary carcinoma of the lung, including a clinico pathologic report of 45 cases at the University Hospital from 1934 to 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982244"}
{"pmid": "20982245", "title": "The patient's part in reconstructive surgery.", "content": "The patient's part in reconstructive surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982245"}
{"pmid": "20982246", "title": "Curare in anesthesia.", "content": "Curare in anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982246"}
{"pmid": "20982248", "title": "OBSTETRIC case report.", "content": "OBSTETRIC case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982248"}
{"pmid": "20982247", "title": "A brief history of roentgenology in Baltimore.", "content": "A brief history of roentgenology in Baltimore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982247"}
{"pmid": "20982249", "title": "Some physiologic aspects of the gall bladder.", "content": "Some physiologic aspects of the gall bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982249"}
{"pmid": "20982250", "title": "Facial and body prosthesis.", "content": "Facial and body prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982250"}
{"pmid": "20982251", "title": "Influence of posture and exercise on water balance in the normal male.", "content": "Influence of posture and exercise on water balance in the normal male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982251"}
{"pmid": "20982252", "title": "The pharmacology of a new series of choline salts.", "content": "The pharmacology of a new series of choline salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982252"}
{"pmid": "20982253", "title": "The effect of commercial growth complex upon the oral structures of normal rats.", "content": "The effect of commercial growth complex upon the oral structures of normal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982253"}
{"pmid": "20982259", "title": "The doctor goes to court.", "content": "The doctor goes to court.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982259"}
{"pmid": "20982270", "title": "Sulphabenzide in the treatment of intestinal disorders.", "content": "Sulphabenzide in the treatment of intestinal disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982270"}
{"pmid": "20982271", "title": "Studies in malaria transmission.", "content": "Studies in malaria transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982271"}
{"pmid": "20982273", "title": "Genito-urinary calculi.", "content": "Genito-urinary calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982273"}
{"pmid": "20982272", "title": "Visceroptosis.", "content": "Visceroptosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982272"}
{"pmid": "20982282", "title": "The ocular manifestations of cerebral pathology.", "content": "The ocular manifestations of cerebral pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982282"}
{"pmid": "20982274", "title": "The association of nasal sinusitis and a raised blood-pressure.", "content": "The association of nasal sinusitis and a raised blood-pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982274"}
{"pmid": "20982283", "title": "Newer concepts of peptic ulcer.", "content": "Newer concepts of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982283"}
{"pmid": "20982295", "title": "The art of seeing.", "content": "The art of seeing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982295"}
{"pmid": "20982296", "title": "Lathyrism in the Central Provinces.", "content": "Lathyrism in the Central Provinces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982296"}
{"pmid": "20982297", "title": "Blood uric acid and chloride in thirty cases of pneumonia.", "content": "Blood uric acid and chloride in thirty cases of pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982297"}
{"pmid": "20982298", "title": "Pyrogenic reaction.", "content": "Pyrogenic reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982298"}
{"pmid": "20982299", "title": "War-neurosis and psychotherapy.", "content": "War-neurosis and psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982299"}
{"pmid": "20982300", "title": "An outline of health services for the Poona District.", "content": "An outline of health services for the Poona District.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982300"}
{"pmid": "20982301", "title": "Penicillin in a case of progressive ascending paralysis of Landry's type.", "content": "Penicillin in a case of progressive ascending paralysis of Landry's type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982301"}
{"pmid": "20982302", "title": "Cibazol in bacillary dysentery.", "content": "Cibazol in bacillary dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982302"}
{"pmid": "20982303", "title": "Sulphonamide anuria.", "content": "Sulphonamide anuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982303"}
{"pmid": "20982304", "title": "Arteriosclerotic diseases.", "content": "Arteriosclerotic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982304"}
{"pmid": "20982305", "title": "Penicillin; some general considerations regarding its uses.", "content": "Penicillin; some general considerations regarding its uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982305"}
{"pmid": "20982306", "title": "Prevention of small-pox.", "content": "Prevention of small-pox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982306"}
{"pmid": "20982307", "title": "Vitamins in general practice.", "content": "Vitamins in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982307"}
{"pmid": "20982308", "title": "EVOLUTION of medical psychology and the duty before us.", "content": "EVOLUTION of medical psychology and the duty before us.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982308"}
{"pmid": "20982309", "title": "Surgery of the thyroid.", "content": "Surgery of the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982309"}
{"pmid": "20982310", "title": "Children's obsessions.", "content": "Children's obsessions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982310"}
{"pmid": "20982311", "title": "Experimental shock; the relation of metabolic derangements of liver and kidney to vascular reactions.", "content": "Experimental shock; the relation of metabolic derangements of liver and kidney to vascular reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982311"}
{"pmid": "20982313", "title": "Biology in wartime.", "content": "Biology in wartime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982313"}
{"pmid": "20982312", "title": "Sterility in women.", "content": "Sterility in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982312"}
{"pmid": "20982314", "title": "Some anatomical factors affecting the stabilising functions of muscles.", "content": "Some anatomical factors affecting the stabilising functions of muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982314"}
{"pmid": "20982315", "title": "Peduncular broncho-pneumonia.", "content": "Peduncular broncho-pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982315"}
{"pmid": "20982316", "title": "Post-arsphenamine jaundice; experience in a military hospital.", "content": "Post-arsphenamine jaundice; experience in a military hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982316"}
{"pmid": "20982317", "title": "The relation of research to the practice of medicine.", "content": "The relation of research to the practice of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982317"}
{"pmid": "20982318", "title": "Hypoproteinemia in surgical patients.", "content": "Hypoproteinemia in surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982318"}
{"pmid": "20982319", "title": "Spontaneous hematoma of the rectus muscle in pregnancy.", "content": "Spontaneous hematoma of the rectus muscle in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982319"}
{"pmid": "20982320", "title": "BRONCHOGENIC carcinoma of the apical portion of the right lung, with widespread metastases.", "content": "BRONCHOGENIC carcinoma of the apical portion of the right lung, with widespread metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982320"}
{"pmid": "20982321", "title": "Caseous tuberculosis of the adrenals with sarcoidosis of other viscera.", "content": "Caseous tuberculosis of the adrenals with sarcoidosis of other viscera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982321"}
{"pmid": "20982322", "title": "BRUCELLOSIS in Iowa; duration of illness.", "content": "BRUCELLOSIS in Iowa; duration of illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982322"}
{"pmid": "20982323", "title": "Medical care for the veteran.", "content": "Medical care for the veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982323"}
{"pmid": "20982324", "title": "Social security and pending legislation affecting it.", "content": "Social security and pending legislation affecting it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982324"}
{"pmid": "20982325", "title": "The doctor in this new day.", "content": "The doctor in this new day.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982325"}
{"pmid": "20982326", "title": "The roentgenologic diagnosis of abdominal abscesses.", "content": "The roentgenologic diagnosis of abdominal abscesses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982326"}
{"pmid": "20982327", "title": "Our new attack on tuberculosis.", "content": "Our new attack on tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982327"}
{"pmid": "20982359", "title": "Highlights and problems related to medical care of veterans.", "content": "Highlights and problems related to medical care of veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982359"}
{"pmid": "20982360", "title": "Dermatitis resulting from exposure to DDT; a preliminary report.", "content": "Dermatitis resulting from exposure to DDT; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982360"}
{"pmid": "20982361", "title": "Endocrine problems in gynecology.", "content": "Endocrine problems in gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982361"}
{"pmid": "20982362", "title": "Some uses of nembutal in obstetrics.", "content": "Some uses of nembutal in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982362"}
{"pmid": "20982363", "title": "When is gonorrhea cured?", "content": "When is gonorrhea cured?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982363"}
{"pmid": "20982364", "title": "Prophylaxis in geriatrics.", "content": "Prophylaxis in geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982364"}
{"pmid": "20982365", "title": "Periarteritis nodosa with case report.", "content": "Periarteritis nodosa with case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982365"}
{"pmid": "20982367", "title": "The doctor on the witness stand.", "content": "The doctor on the witness stand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982367"}
{"pmid": "20982366", "title": "Acute appendicitis with complications.", "content": "Acute appendicitis with complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982366"}
{"pmid": "20982368", "title": "Chronic disease of the breast.", "content": "Chronic disease of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982368"}
{"pmid": "20982369", "title": "Helpful considerations in diagnosis of surgical cases of jaundice.", "content": "Helpful considerations in diagnosis of surgical cases of jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982369"}
{"pmid": "20982370", "title": "Disabilities of the foot.", "content": "Disabilities of the foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982370"}
{"pmid": "20982378", "title": "Rapid chemical disinfection of clean unwashed skin.", "content": "Rapid chemical disinfection of clean unwashed skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982378"}
{"pmid": "20982379", "title": "Blood-transfusion in Indian famine.", "content": "Blood-transfusion in Indian famine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982379"}
{"pmid": "20982377", "title": "Leukaemia treated with urethane, compared with deep x-ray therapy.", "content": "Leukaemia treated with urethane, compared with deep x-ray therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982377"}
{"pmid": "20982380", "title": "Serum phosphatase in lathyrism.", "content": "Serum phosphatase in lathyrism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982380"}
{"pmid": "20982382", "title": "NATIONAL Health Service Bill.", "content": "NATIONAL Health Service Bill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982382"}
{"pmid": "20982383", "title": "OVERDOSE of moryl.", "content": "OVERDOSE of moryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982383"}
{"pmid": "20982381", "title": "Rapid death following injection of antitetanic serum.", "content": "Rapid death following injection of antitetanic serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982381"}
{"pmid": "20982384", "title": "Fowler's position.", "content": "Fowler's position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982384"}
{"pmid": "20982385", "title": "Paralysis agitans.", "content": "Paralysis agitans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982385"}
{"pmid": "20982386", "title": "Orthopaedic and rehabilitation service of the Royal Air Force.", "content": "Orthopaedic and rehabilitation service of the Royal Air Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982386"}
{"pmid": "20982387", "title": "Lipodystrophy and hepatomegaly, with diabetes, lipaemia, and other metabolic disturbances; a case throwing new light on the action of insulin.", "content": "Lipodystrophy and hepatomegaly, with diabetes, lipaemia, and other metabolic disturbances; a case throwing new light on the action of insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982387"}
{"pmid": "20982388", "title": "Aminothiazole in the treatment of thyrotoxicosis.", "content": "Aminothiazole in the treatment of thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982388"}
{"pmid": "20982389", "title": "Nutritional neuropathy in prisoners-of-war and internees from Hong-Kong.", "content": "Nutritional neuropathy in prisoners-of-war and internees from Hong-Kong.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982389"}
{"pmid": "20982390", "title": "Tolerance to octyl nitrite in achalasia of the cardia.", "content": "Tolerance to octyl nitrite in achalasia of the cardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982390"}
{"pmid": "20982392", "title": "PRACTITIONER'S income.", "content": "PRACTITIONER'S income.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982392"}
{"pmid": "20982391", "title": "Penicillin in subacute bacterial endocarditis.", "content": "Penicillin in subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982391"}
{"pmid": "20982393", "title": "REMUNERATION of the general practitioner.", "content": "REMUNERATION of the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982393"}
{"pmid": "20982394", "title": "The secular trend in the stillbirth-rate.", "content": "The secular trend in the stillbirth-rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982394"}
{"pmid": "20982400", "title": "Importance of student research in the medical schools.", "content": "Importance of student research in the medical schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982400"}
{"pmid": "20982399", "title": "Ideals of pedagogy in their application to medicine.", "content": "Ideals of pedagogy in their application to medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982399"}
{"pmid": "20982401", "title": "Intravenous anaesthesia.", "content": "Intravenous anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982401"}
{"pmid": "20982402", "title": "Concerning the treatment of inoperable malignant disease in general practice.", "content": "Concerning the treatment of inoperable malignant disease in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982402"}
{"pmid": "20982403", "title": "Common infections of the skin.", "content": "Common infections of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982403"}
{"pmid": "20982404", "title": "The role of surgery in the treatment of bleeding peptic ulcer.", "content": "The role of surgery in the treatment of bleeding peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982404"}
{"pmid": "20982405", "title": "The use of penicillin in infections of the ear, nose and the throat.", "content": "The use of penicillin in infections of the ear, nose and the throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982405"}
{"pmid": "20982406", "title": "Therapy in the treatment of congenital duodonal atresia.", "content": "Therapy in the treatment of congenital duodonal atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982406"}
{"pmid": "20982407", "title": "Medicine and the common man.", "content": "Medicine and the common man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982407"}
{"pmid": "20982418", "title": "Health bills pending in Congress.", "content": "Health bills pending in Congress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982418"}
{"pmid": "20982419", "title": "Osseous syphilis; report of a case.", "content": "Osseous syphilis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982419"}
{"pmid": "20982420", "title": "Generalized dermatitis from pediculosis capitis.", "content": "Generalized dermatitis from pediculosis capitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982420"}
{"pmid": "20982421", "title": "Hepatoma, with metastases; clinicopathological exercises.", "content": "Hepatoma, with metastases; clinicopathological exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982421"}
{"pmid": "20982422", "title": "Metastases of carcinoma of cervix; clinicopathological exercises.", "content": "Metastases of carcinoma of cervix; clinicopathological exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982422"}
{"pmid": "20982423", "title": "Penetrating wounds of the abdomen.", "content": "Penetrating wounds of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982423"}
{"pmid": "20982424", "title": "How to prevent death from breast cancer.", "content": "How to prevent death from breast cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982424"}
{"pmid": "20982425", "title": "Unusual types of appendicitis.", "content": "Unusual types of appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982425"}
{"pmid": "20982426", "title": "Injuries of the elbow in children.", "content": "Injuries of the elbow in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982426"}
{"pmid": "20982427", "title": "Orthopedic interest in a fracture.", "content": "Orthopedic interest in a fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982427"}
{"pmid": "20982428", "title": "The symptomatology of uterine retrodisplacements.", "content": "The symptomatology of uterine retrodisplacements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982428"}
{"pmid": "20982429", "title": "Posterior sclerotomy and lens extraction in acute glaucoma secondary to senile cataract.", "content": "Posterior sclerotomy and lens extraction in acute glaucoma secondary to senile cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982429"}
{"pmid": "20982430", "title": "Estrogenic therapy in diabetes.", "content": "Estrogenic therapy in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982430"}
{"pmid": "20982435", "title": "Granuloma coccidioídico.", "content": "Granuloma coccidioídico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982435"}
{"pmid": "20982460", "title": "A test for bile.", "content": "A test for bile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982460"}
{"pmid": "20982461", "title": "Bladder injury at cesarean section; a case report.", "content": "Bladder injury at cesarean section; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982461"}
{"pmid": "20982488", "title": "Sulfonamide susceptibility of stock strains of dysentery bacilli and of strains from recent epidemics.", "content": "Sulfonamide susceptibility of stock strains of dysentery bacilli and of strains from recent epidemics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982488"}
{"pmid": "20982489", "title": "Comparative study of hypertensinase and proteinase activity of blood plasma.", "content": "Comparative study of hypertensinase and proteinase activity of blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982489"}
{"pmid": "20982490", "title": "A study of Rettger's bacillus and related bacteria.", "content": "A study of Rettger's bacillus and related bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982490"}
{"pmid": "20982492", "title": "Relative efficiency of the proteins in polished rice and in enriched wheat flour.", "content": "Relative efficiency of the proteins in polished rice and in enriched wheat flour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982492"}
{"pmid": "20982493", "title": "Potentiating and pressor action of some N-substituted hexylamines.", "content": "Potentiating and pressor action of some N-substituted hexylamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982493"}
{"pmid": "20982491", "title": "Serological reactions of levans formed from sucrose and raffinose by certain bacilli.", "content": "Serological reactions of levans formed from sucrose and raffinose by certain bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982491"}
{"pmid": "20982494", "title": "Protective action of certain compounds against dietary hepatic damage in the rat.", "content": "Protective action of certain compounds against dietary hepatic damage in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982494"}
{"pmid": "20982495", "title": "Experiments with protoporphyrin.", "content": "Experiments with protoporphyrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982495"}
{"pmid": "20982496", "title": "Early changes induced in purkinje cells of rabbit by single massive doses of roentgen rays.", "content": "Early changes induced in purkinje cells of rabbit by single massive doses of roentgen rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982496"}
{"pmid": "20982497", "title": "Time course of changes in sensory cells of trigeminal ganglion of the rabbit following irradiation.", "content": "Time course of changes in sensory cells of trigeminal ganglion of the rabbit following irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982497"}
{"pmid": "20982498", "title": "Bone growth in paralyzed limbs.", "content": "Bone growth in paralyzed limbs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982498"}
{"pmid": "20982500", "title": "Metabolism of nicotinamide, nicotinic acid and diethylamide of nicotinic acid (coramine) by newborn and premature infants.", "content": "Metabolism of nicotinamide, nicotinic acid and diethylamide of nicotinic acid (coramine) by newborn and premature infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982500"}
{"pmid": "20982499", "title": "Serial transmission of the milk agent of mouse mammary carcinoma.", "content": "Serial transmission of the milk agent of mouse mammary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982499"}
{"pmid": "20982502", "title": "Biosynthesis of nicotinamide in man.", "content": "Biosynthesis of nicotinamide in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982502"}
{"pmid": "20982501", "title": "Vitamin E levels in maternal and fetal blood plasma.", "content": "Vitamin E levels in maternal and fetal blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982501"}
{"pmid": "20982503", "title": "Functional and fatty changes in liver during chronic vitamin B complex deficiency.", "content": "Functional and fatty changes in liver during chronic vitamin B complex deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982503"}
{"pmid": "20982504", "title": "Role played by leucocytes, platelets and plasma trypsin in peptone shock in the dog.", "content": "Role played by leucocytes, platelets and plasma trypsin in peptone shock in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982504"}
{"pmid": "20982505", "title": "Heredity of Rh blood types; improved nomenclature; additional family studies with special reference to Hr.", "content": "Heredity of Rh blood types; improved nomenclature; additional family studies with special reference to Hr.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982505"}
{"pmid": "20982506", "title": "Pathogenesis of erythroblastosis fetalis.", "content": "Pathogenesis of erythroblastosis fetalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982506"}
{"pmid": "20982507", "title": "Antibiotic activity of extract of western red cedar heartwood.", "content": "Antibiotic activity of extract of western red cedar heartwood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982507"}
{"pmid": "20982508", "title": "Immunological studies of dengue fever and Colorado tick fever.", "content": "Immunological studies of dengue fever and Colorado tick fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982508"}
{"pmid": "20982509", "title": "A hemorrhagic syndrome induced by derivatives of 3-hydroxy-1,4-naphthoquinone.", "content": "A hemorrhagic syndrome induced by derivatives of 3-hydroxy-1,4-naphthoquinone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982509"}
{"pmid": "20982510", "title": "Chemotherapy of experimental leishmaniasis.", "content": "Chemotherapy of experimental leishmaniasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982510"}
{"pmid": "20982512", "title": "Electrocardiographic changes in hemorrhage and ischemic compression shock.", "content": "Electrocardiographic changes in hemorrhage and ischemic compression shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982512"}
{"pmid": "20982511", "title": "Effects of inflammation (turpentine abscess) on iron absorption.", "content": "Effects of inflammation (turpentine abscess) on iron absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982511"}
{"pmid": "20982513", "title": "Respiration of heart muscle slices from rats in the terminal stage of hemorrhagic shock.", "content": "Respiration of heart muscle slices from rats in the terminal stage of hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982513"}
{"pmid": "20982514", "title": "Thiamin deficiency and susceptibility of rats and mice to infection with Salmonella typhi murium.", "content": "Thiamin deficiency and susceptibility of rats and mice to infection with Salmonella typhi murium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982514"}
{"pmid": "20982515", "title": "Rh antigen and hapten; nature of antigen and its isolation from erythrocyte stroma.", "content": "Rh antigen and hapten; nature of antigen and its isolation from erythrocyte stroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982515"}
{"pmid": "20982516", "title": "Portal vein ligation and the Eck fistula in the rat.", "content": "Portal vein ligation and the Eck fistula in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982516"}
{"pmid": "20982517", "title": "Number of Peyer's patches in mice belonging to high and low mammary tumor strains.", "content": "Number of Peyer's patches in mice belonging to high and low mammary tumor strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982517"}
{"pmid": "20982518", "title": "A quantitative method for the study of chromatolysis.", "content": "A quantitative method for the study of chromatolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982518"}
{"pmid": "20982519", "title": "Removal of bone marrow in living animals.", "content": "Removal of bone marrow in living animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982519"}
{"pmid": "20982520", "title": "Perosis caused by feeding high levels of thiouracil.", "content": "Perosis caused by feeding high levels of thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982520"}
{"pmid": "20982521", "title": "Serum precipitation reaction in rheumatic fever and in other conditions.", "content": "Serum precipitation reaction in rheumatic fever and in other conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982521"}
{"pmid": "20982522", "title": "The antagonistic action of choline and its triethyl analogue.", "content": "The antagonistic action of choline and its triethyl analogue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982522"}
{"pmid": "20982523", "title": "Anticoagulant activity of the trypsin inhibitor from soya bean flour.", "content": "Anticoagulant activity of the trypsin inhibitor from soya bean flour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982523"}
{"pmid": "20982524", "title": "Protective effects of glutathione and cysteine against alloxan diabetes in the rat.", "content": "Protective effects of glutathione and cysteine against alloxan diabetes in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982524"}
{"pmid": "20982532", "title": "Pre-sanatorium.", "content": "Pre-sanatorium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982532"}
{"pmid": "20982540", "title": "Congenital aniridia.", "content": "Congenital aniridia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982540"}
{"pmid": "20982591", "title": "The role of the anesthesiologist in the prevention and treatment of thrombophlebitis.", "content": "The role of the anesthesiologist in the prevention and treatment of thrombophlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982591"}
{"pmid": "20982592", "title": "The surgical management of gastric and duodenal ulcers.", "content": "The surgical management of gastric and duodenal ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982592"}
{"pmid": "20982593", "title": "Extrapleural pneumothorax; its limited usefulness.", "content": "Extrapleural pneumothorax; its limited usefulness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982593"}
{"pmid": "20982594", "title": "Use of omentum as a pelvic diaphragm following the resection of perforating carcinoma of the rectosigmoid.", "content": "Use of omentum as a pelvic diaphragm following the resection of perforating carcinoma of the rectosigmoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982594"}
{"pmid": "20982595", "title": "Digitalis and the cardiovascular system.", "content": "Digitalis and the cardiovascular system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982595"}
{"pmid": "20982628", "title": "Carcinoma of the fundus uteri.", "content": "Carcinoma of the fundus uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982628"}
{"pmid": "20982629", "title": "Periarteritis nodosa; clinical manifestations and postmortem findings with a report of six cases.", "content": "Periarteritis nodosa; clinical manifestations and postmortem findings with a report of six cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982629"}
{"pmid": "20982630", "title": "The effect of transthoracic vagotomy upon the functions of the stomach and upon the early clinical course of patients with peptic ulcer.", "content": "The effect of transthoracic vagotomy upon the functions of the stomach and upon the early clinical course of patients with peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982630"}
{"pmid": "20982631", "title": "The use of perforated acrylic implants following enucleation.", "content": "The use of perforated acrylic implants following enucleation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982631"}
{"pmid": "20982632", "title": "Failure of lipid metabolism; proctologic significance.", "content": "Failure of lipid metabolism; proctologic significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982632"}
{"pmid": "20982633", "title": "Primary and secondary metastases from cancer of the colon and rectum.", "content": "Primary and secondary metastases from cancer of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982633"}
{"pmid": "20982634", "title": "Use of neostigmine (prostigmine) in subacute poliomyelitis.", "content": "Use of neostigmine (prostigmine) in subacute poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982634"}
{"pmid": "20982635", "title": "Importance of vitamins of the B complex in clinical medicine.", "content": "Importance of vitamins of the B complex in clinical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982635"}
{"pmid": "20982636", "title": "North Carolina School-Health Coordinating Service.", "content": "North Carolina School-Health Coordinating Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982636"}
{"pmid": "20982637", "title": "Some future problems in allergy.", "content": "Some future problems in allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982637"}
{"pmid": "20982638", "title": "The disabled, the physician and employment.", "content": "The disabled, the physician and employment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982638"}
{"pmid": "20982639", "title": "Industrial health; a report from the field.", "content": "Industrial health; a report from the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982639"}
{"pmid": "20982640", "title": "Common skin diseases in children.", "content": "Common skin diseases in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982640"}
{"pmid": "20982641", "title": "Pre-measles encephalitis.", "content": "Pre-measles encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982641"}
{"pmid": "20982642", "title": "Experiments in medical education and medical care in a new medical school.", "content": "Experiments in medical education and medical care in a new medical school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982642"}
{"pmid": "20982643", "title": "Some usual and unusual mechanisms of abdominal pain.", "content": "Some usual and unusual mechanisms of abdominal pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982643"}
{"pmid": "20982644", "title": "Protein solution in surgical practice.", "content": "Protein solution in surgical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982644"}
{"pmid": "20982645", "title": "The use of diathermy in general practice.", "content": "The use of diathermy in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982645"}
{"pmid": "20982646", "title": "Punishment by incineration.", "content": "Punishment by incineration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982646"}
{"pmid": "20982656", "title": "Tetralogy of Fallot.", "content": "Tetralogy of Fallot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982656"}
{"pmid": "20982657", "title": "Clinical observations in literature.", "content": "Clinical observations in literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982657"}
{"pmid": "20982658", "title": "The incidence of site of mandibular fractures.", "content": "The incidence of site of mandibular fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982658"}
{"pmid": "20982663", "title": "The mammary tumor agent and its implication in cancer research.", "content": "The mammary tumor agent and its implication in cancer research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982663"}
{"pmid": "20982662", "title": "Harvey, Riolan, and the discovery of the circulation of the blood.", "content": "Harvey, Riolan, and the discovery of the circulation of the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982662"}
{"pmid": "20982664", "title": "Changes in liver function during experimentally induced human hepatitis.", "content": "Changes in liver function during experimentally induced human hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982664"}
{"pmid": "20982665", "title": "Genetic analysis of the induction of tumors by methylcholanthrene; mutation from brown to black with a concomitant increase of susceptibility to fibrosarcoma.", "content": "Genetic analysis of the induction of tumors by methylcholanthrene; mutation from brown to black with a concomitant increase of susceptibility to fibrosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982665"}
{"pmid": "20982666", "title": "Electroencephalographic changes after eye opening and visual stimulation.", "content": "Electroencephalographic changes after eye opening and visual stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982666"}
{"pmid": "20982667", "title": "Benzyl penicillin; failure to sterilize the blood in subacute bacterial endocarditis.", "content": "Benzyl penicillin; failure to sterilize the blood in subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982667"}
{"pmid": "20982668", "title": "Eosinophilia, ancylostomiasis, and strongloidosis in the South Pacific area.", "content": "Eosinophilia, ancylostomiasis, and strongloidosis in the South Pacific area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982668"}
{"pmid": "20982669", "title": "Salt depletion, peripheral vascular collapse, and the treatment of diabetic acidosis.", "content": "Salt depletion, peripheral vascular collapse, and the treatment of diabetic acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982669"}
{"pmid": "20982670", "title": "The possibility of detecting individual proteins in blood serum by differentiation of solubility curves in concentrated sodium sulfate solutions.", "content": "The possibility of detecting individual proteins in blood serum by differentiation of solubility curves in concentrated sodium sulfate solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982670"}
{"pmid": "20982671", "title": "The housing, care, and surgical handling of laboratory primates.", "content": "The housing, care, and surgical handling of laboratory primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982671"}
{"pmid": "20982679", "title": "The R.A.M.C. in Thailand.", "content": "The R.A.M.C. in Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982679"}
{"pmid": "20982678", "title": "The R.A.M.C. in Thailand p.o.w. camps.", "content": "The R.A.M.C. in Thailand p.o.w. camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982678"}
{"pmid": "20982680", "title": "Resuscitation under spinal anaesthesia without drugs.", "content": "Resuscitation under spinal anaesthesia without drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982680"}
{"pmid": "20982681", "title": "Experiences with cholera in a jungle camp in Thailand.", "content": "Experiences with cholera in a jungle camp in Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982681"}
{"pmid": "20982682", "title": "A series of over 100 amputations of the thigh for tropical ulcer.", "content": "A series of over 100 amputations of the thigh for tropical ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982682"}
{"pmid": "20982683", "title": "The nature of starvation amblyopia.", "content": "The nature of starvation amblyopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982683"}
{"pmid": "20982684", "title": "European into coolie; p.o.w. adapt themselves to the tropical villagers' diseases.", "content": "European into coolie; p.o.w. adapt themselves to the tropical villagers' diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982684"}
{"pmid": "20982685", "title": "Leptospirosis (Weil's disease).", "content": "Leptospirosis (Weil's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982685"}
{"pmid": "20982686", "title": "CONDITION of battle casualties returned from European Theater of Operations.", "content": "CONDITION of battle casualties returned from European Theater of Operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982686"}
{"pmid": "20982687", "title": "A report of ten cases of tetanus.", "content": "A report of ten cases of tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982687"}
{"pmid": "20982688", "title": "The surgical biopsy.", "content": "The surgical biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982688"}
{"pmid": "20982689", "title": "Infection of war wounds by Clostridium organisms (gas gangrehe).", "content": "Infection of war wounds by Clostridium organisms (gas gangrehe).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982689"}
{"pmid": "20982691", "title": "An instance of possible penicillin sensitivity.", "content": "An instance of possible penicillin sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982691"}
{"pmid": "20982690", "title": "Identification of x-ray films in the field; flash box system of marking.", "content": "Identification of x-ray films in the field; flash box system of marking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982690"}
{"pmid": "20982692", "title": "A new type of folding chest, designed for artillery battalion aid stations in the offensive.", "content": "A new type of folding chest, designed for artillery battalion aid stations in the offensive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982692"}
{"pmid": "20982711", "title": "Malnutrition in repatriated prisoners of war.", "content": "Malnutrition in repatriated prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982711"}
{"pmid": "20982712", "title": "Observations and data on prevention of poison-oak dermatitis.", "content": "Observations and data on prevention of poison-oak dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982712"}
{"pmid": "20982713", "title": "Comparative evaluation of preparations for the prophylaxis and treatment of fungous infections of feet.", "content": "Comparative evaluation of preparations for the prophylaxis and treatment of fungous infections of feet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982713"}
{"pmid": "20982714", "title": "Diagnosis of infestation with Sarcoptes scabiei var. hominis.", "content": "Diagnosis of infestation with Sarcoptes scabiei var. hominis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982714"}
{"pmid": "20982715", "title": "Aerodontalgia occurring during oxygen indoctrination in the low-pressure chamber.", "content": "Aerodontalgia occurring during oxygen indoctrination in the low-pressure chamber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982715"}
{"pmid": "20982716", "title": "Malaria in Panama.", "content": "Malaria in Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982716"}
{"pmid": "20982717", "title": "PARTITIONING of barracks; effect on morbidity rates from respiratory disease.", "content": "PARTITIONING of barracks; effect on morbidity rates from respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982717"}
{"pmid": "20982718", "title": "Fractures of the shaft of femur; early treatment on a hospital ship.", "content": "Fractures of the shaft of femur; early treatment on a hospital ship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982718"}
{"pmid": "20982720", "title": "Dental problems on submarines.", "content": "Dental problems on submarines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982720"}
{"pmid": "20982719", "title": "An experience with atabrine aboard a troop transport.", "content": "An experience with atabrine aboard a troop transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982719"}
{"pmid": "20982721", "title": "Shigellosis studies; clinical observations on dysentery caused by Shigella flexneri III.", "content": "Shigellosis studies; clinical observations on dysentery caused by Shigella flexneri III.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982721"}
{"pmid": "20982722", "title": "Trivial symptoms following extensive skull fracture.", "content": "Trivial symptoms following extensive skull fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982722"}
{"pmid": "20982723", "title": "Ophthalmic disease treated with penicillin.", "content": "Ophthalmic disease treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982723"}
{"pmid": "20982725", "title": "Treatment of infected sebaceous cysts.", "content": "Treatment of infected sebaceous cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982725"}
{"pmid": "20982724", "title": "Hookworm disease in infants; report of two fatal cases.", "content": "Hookworm disease in infants; report of two fatal cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982724"}
{"pmid": "20982727", "title": "PHYCHIATRY and the problem of homosexuality.", "content": "PHYCHIATRY and the problem of homosexuality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982727"}
{"pmid": "20982726", "title": "A heavy-duty, high-capacity portable suction pump for surgical use.", "content": "A heavy-duty, high-capacity portable suction pump for surgical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982726"}
{"pmid": "20982728", "title": "Medical surveys for pulmonary tuberculosis.", "content": "Medical surveys for pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982728"}
{"pmid": "20982729", "title": "Fundamental research in relation to the community.", "content": "Fundamental research in relation to the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982729"}
{"pmid": "20982730", "title": "Planned research.", "content": "Planned research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982730"}
{"pmid": "20982731", "title": "Planning and organising research.", "content": "Planning and organising research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982731"}
{"pmid": "20982732", "title": "Economic aspects of research.", "content": "Economic aspects of research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982732"}
{"pmid": "20982733", "title": "The human factor.", "content": "The human factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982733"}
{"pmid": "20982734", "title": "Education and training of research workers.", "content": "Education and training of research workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982734"}
{"pmid": "20982735", "title": "The place of science in town and country planning.", "content": "The place of science in town and country planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982735"}
{"pmid": "20982736", "title": "International scientific co-operation.", "content": "International scientific co-operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982736"}
{"pmid": "20982742", "title": "Emergent energy.", "content": "Emergent energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982742"}
{"pmid": "20982743", "title": "New cosmic ray radiosonde techniques.", "content": "New cosmic ray radiosonde techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982743"}
{"pmid": "20982744", "title": "Enzymes hydrolyzing ribo- and desoxyribonucleic acids.", "content": "Enzymes hydrolyzing ribo- and desoxyribonucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982744"}
{"pmid": "20982745", "title": "Sounding upper atmosphere by radiosonde.", "content": "Sounding upper atmosphere by radiosonde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982745"}
{"pmid": "20982737", "title": "An empirical evolutionary generalization viewed from the standpoint of phenogenetics.", "content": "An empirical evolutionary generalization viewed from the standpoint of phenogenetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982737"}
{"pmid": "20982746", "title": "Coal tar and its derivatives; by-product recovery from coal tars in India.", "content": "Coal tar and its derivatives; by-product recovery from coal tars in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982746"}
{"pmid": "20982738", "title": "Chance as a cause of changes in gene frequency within pure breeds of livestock.", "content": "Chance as a cause of changes in gene frequency within pure breeds of livestock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982738"}
{"pmid": "20982739", "title": "Observations and experiments on the cave fish Pimelodella kronei and its relatives.", "content": "Observations and experiments on the cave fish Pimelodella kronei and its relatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982739"}
{"pmid": "20982747", "title": "Australian agar agar industry.", "content": "Australian agar agar industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982747"}
{"pmid": "20982748", "title": "Electrolytic reduction of nitro compounds; the electrolytic reduction of nitrobenzene.", "content": "Electrolytic reduction of nitro compounds; the electrolytic reduction of nitrobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982748"}
{"pmid": "20982740", "title": "An estimate of the number of cell generations preceding sperm formation in Drosophila melanogaster.", "content": "An estimate of the number of cell generations preceding sperm formation in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982740"}
{"pmid": "20982750", "title": "Electrolytic reduction of nitro compounds; the electrolytic reduction of nitrobenzene to para aminophenol.", "content": "Electrolytic reduction of nitro compounds; the electrolytic reduction of nitrobenzene to para aminophenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982750"}
{"pmid": "20982749", "title": "Electrolytic reduction of nitro compounds; the electrolytic production of benzidine.", "content": "Electrolytic reduction of nitro compounds; the electrolytic production of benzidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982749"}
{"pmid": "20982741", "title": "Structural chromosome variability in urban and rural populations of Drosophila funebris.", "content": "Structural chromosome variability in urban and rural populations of Drosophila funebris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982741"}
{"pmid": "20982751", "title": "Yeast growth method for thiamin estimation.", "content": "Yeast growth method for thiamin estimation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982751"}
{"pmid": "20982752", "title": "SCIENTIFIC management and the Civil Service.", "content": "SCIENTIFIC management and the Civil Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982752"}
{"pmid": "20982753", "title": "Nutrients in British-grown and imported wheat.", "content": "Nutrients in British-grown and imported wheat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982753"}
{"pmid": "20982754", "title": "Higher education in the British Colonial Empire.", "content": "Higher education in the British Colonial Empire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982754"}
{"pmid": "20982755", "title": "Organs of equilibrium in flying insects.", "content": "Organs of equilibrium in flying insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982755"}
{"pmid": "20982756", "title": "Bacterial root nodules in the Zygophyllaceae.", "content": "Bacterial root nodules in the Zygophyllaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982756"}
{"pmid": "20982757", "title": "Staining the chromosomes of yeast by the Feulgen technique.", "content": "Staining the chromosomes of yeast by the Feulgen technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982757"}
{"pmid": "20982759", "title": "Coupling of phosphorylation and oxidation processes.", "content": "Coupling of phosphorylation and oxidation processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982759"}
{"pmid": "20982758", "title": "Toxicity of D.D.T. to man.", "content": "Toxicity of D.D.T. to man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982758"}
{"pmid": "20982761", "title": "Effect of duration of loading on the strength of glass.", "content": "Effect of duration of loading on the strength of glass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982761"}
{"pmid": "20982760", "title": "Sugar of human semen.", "content": "Sugar of human semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982760"}
{"pmid": "20982762", "title": "A simple electrophoresis method.", "content": "A simple electrophoresis method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982762"}
{"pmid": "20982763", "title": "Translocation of copper ions in plants.", "content": "Translocation of copper ions in plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982763"}
{"pmid": "20982764", "title": "The scientist and his government.", "content": "The scientist and his government.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982764"}
{"pmid": "20982765", "title": "Suppressed-range recording peak voltmeter.", "content": "Suppressed-range recording peak voltmeter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982765"}
{"pmid": "20982767", "title": "A contact modulated amplifier to replace sensitive suspension galvanometers.", "content": "A contact modulated amplifier to replace sensitive suspension galvanometers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982767"}
{"pmid": "20982766", "title": "Range extender for general radio 760A sound analyzer.", "content": "Range extender for general radio 760A sound analyzer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982766"}
{"pmid": "20982768", "title": "The biological basis of imagination.", "content": "The biological basis of imagination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982768"}
{"pmid": "20982769", "title": "Science and world community.", "content": "Science and world community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982769"}
{"pmid": "20982770", "title": "Where are America's research resources?", "content": "Where are America's research resources?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982770"}
{"pmid": "20982771", "title": "Men, mastodons, and myth.", "content": "Men, mastodons, and myth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982771"}
{"pmid": "20982772", "title": "The need for science writing in the press.", "content": "The need for science writing in the press.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982772"}
{"pmid": "20982773", "title": "Gold shadowing in electron microscopy.", "content": "Gold shadowing in electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982773"}
{"pmid": "20982774", "title": "The nature and need of educational research.", "content": "The nature and need of educational research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982774"}
{"pmid": "20982775", "title": "The structure and synthesis of the liver L. casei factor.", "content": "The structure and synthesis of the liver L. casei factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982775"}
{"pmid": "20982776", "title": "Famine edema and the mechanism of its formation.", "content": "Famine edema and the mechanism of its formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982776"}
{"pmid": "20982777", "title": "Antibacterial action of phenanthrene-related substances.", "content": "Antibacterial action of phenanthrene-related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982777"}
{"pmid": "20982778", "title": "Carbon dioxide as an essential factor in the bacterial decomposition of cellulose.", "content": "Carbon dioxide as an essential factor in the bacterial decomposition of cellulose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982778"}
{"pmid": "20982793", "title": "The intraneural topography of the radial, median and ulnar nerves.", "content": "The intraneural topography of the radial, median and ulnar nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982793"}
{"pmid": "20982794", "title": "The role of galvanism in the treatment of denervated voluntary muscle in man.", "content": "The role of galvanism in the treatment of denervated voluntary muscle in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982794"}
{"pmid": "20982795", "title": "The interrelation of the striopallidum and the thalamus in the macaque monkey.", "content": "The interrelation of the striopallidum and the thalamus in the macaque monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982795"}
{"pmid": "20982796", "title": "Note on the lateral geniculate body.", "content": "Note on the lateral geniculate body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982796"}
{"pmid": "20982797", "title": "The psychoneurotic veteran.", "content": "The psychoneurotic veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982797"}
{"pmid": "20982798", "title": "Neurological complications of essential purpura haemorrhagica.", "content": "Neurological complications of essential purpura haemorrhagica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982798"}
{"pmid": "20982799", "title": "The physician's field workers for mental health.", "content": "The physician's field workers for mental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982799"}
{"pmid": "20982800", "title": "Neurosis; a progressive or self-limiting disease?", "content": "Neurosis; a progressive or self-limiting disease?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982800"}
{"pmid": "20982802", "title": "Numerical and regional distribution of taste buds on the tongue of the bird.", "content": "Numerical and regional distribution of taste buds on the tongue of the bird.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982802"}
{"pmid": "20982801", "title": "Encephalitis, type undetermined.", "content": "Encephalitis, type undetermined.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982801"}
{"pmid": "20982803", "title": "The pyramidal tract; the sensitivity of axons to maximal injury of cells of origin in the cat.", "content": "The pyramidal tract; the sensitivity of axons to maximal injury of cells of origin in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982803"}
{"pmid": "20982804", "title": "The olivary peduncle and other fiber projections of the superior olivary complex.", "content": "The olivary peduncle and other fiber projections of the superior olivary complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982804"}
{"pmid": "20982805", "title": "Connections of the cerebral cortex; the albino rat; topography of the cortical areas.", "content": "Connections of the cerebral cortex; the albino rat; topography of the cortical areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982805"}
{"pmid": "20982806", "title": "Outcome of the tic syndrome.", "content": "Outcome of the tic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982806"}
{"pmid": "20982807", "title": "Psychopath-like behavior in war neurotics.", "content": "Psychopath-like behavior in war neurotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982807"}
{"pmid": "20982809", "title": "Psychiatric study of a patient with paroxysmal hypothalamic dysfunction.", "content": "Psychiatric study of a patient with paroxysmal hypothalamic dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982809"}
{"pmid": "20982808", "title": "Neuropathologic manifestations found in a Japanese prison camp.", "content": "Neuropathologic manifestations found in a Japanese prison camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982808"}
{"pmid": "20982810", "title": "Sleep and third circulation; an attempt to solve the problem of sleep.", "content": "Sleep and third circulation; an attempt to solve the problem of sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982810"}
{"pmid": "20982811", "title": "Speech disorders in World War II; dysarthria and dyslalia; methods of examination.", "content": "Speech disorders in World War II; dysarthria and dyslalia; methods of examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982811"}
{"pmid": "20982812", "title": "Shock treatment of psychoses associated with pregnancy.", "content": "Shock treatment of psychoses associated with pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982812"}
{"pmid": "20982813", "title": "Skin reactions observed under wartime stress.", "content": "Skin reactions observed under wartime stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982813"}
{"pmid": "20982814", "title": "Intracranial aneurysm and polycystic kidneys.", "content": "Intracranial aneurysm and polycystic kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982814"}
{"pmid": "20982815", "title": "Involuntary imitative movements of contralateral hand.", "content": "Involuntary imitative movements of contralateral hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982815"}
{"pmid": "20982816", "title": "Some relationships between maturation and acculturation.", "content": "Some relationships between maturation and acculturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982816"}
{"pmid": "20982817", "title": "Cultural patterning of maturation in selected primitive societies.", "content": "Cultural patterning of maturation in selected primitive societies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982817"}
{"pmid": "20982818", "title": "Psychotherapy and psychoanalysis in the treatment of children.", "content": "Psychotherapy and psychoanalysis in the treatment of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982818"}
{"pmid": "20982819", "title": "Totemistic mentation and its implications for child analysis.", "content": "Totemistic mentation and its implications for child analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982819"}
{"pmid": "20982820", "title": "Analytical psychology applied to children.", "content": "Analytical psychology applied to children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982820"}
{"pmid": "20982821", "title": "A fundamental concept for analytical psychology of childhood; paternus and materna.", "content": "A fundamental concept for analytical psychology of childhood; paternus and materna.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982821"}
{"pmid": "20982822", "title": "The decisive influence of parental attitudes.", "content": "The decisive influence of parental attitudes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982822"}
{"pmid": "20982823", "title": "Should the child be sent to an institution?", "content": "Should the child be sent to an institution?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982823"}
{"pmid": "20982824", "title": "Child guidance work based on psychoanalytic concepts.", "content": "Child guidance work based on psychoanalytic concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982824"}
{"pmid": "20982825", "title": "Social psychiatry as an aid to child analysis.", "content": "Social psychiatry as an aid to child analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982825"}
{"pmid": "20982826", "title": "Educational advantages enjoyed by handicapped children.", "content": "Educational advantages enjoyed by handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982826"}
{"pmid": "20982827", "title": "Social nursing.", "content": "Social nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982827"}
{"pmid": "20982828", "title": "Male fever nurse; pioneer in the field.", "content": "Male fever nurse; pioneer in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982828"}
{"pmid": "20982829", "title": "Anaesthetics in relation to nursing.", "content": "Anaesthetics in relation to nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982829"}
{"pmid": "20982830", "title": "Puerperal sepsis.", "content": "Puerperal sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982830"}
{"pmid": "20982831", "title": "EYE injuries; penicillin.", "content": "EYE injuries; penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982831"}
{"pmid": "20982832", "title": "Structure and diseases of the nose and throat; anatomy and physiology of the nose.", "content": "Structure and diseases of the nose and throat; anatomy and physiology of the nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982832"}
{"pmid": "20982833", "title": "RESPONSIBILITIES of superintendent health visitors.", "content": "RESPONSIBILITIES of superintendent health visitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982833"}
{"pmid": "20982835", "title": "Interlobar empyema.", "content": "Interlobar empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982835"}
{"pmid": "20982836", "title": "Staphylococcal infections of newborn infants.", "content": "Staphylococcal infections of newborn infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982836"}
{"pmid": "20982834", "title": "The mock accident in first-aid training; poisoning by carbon monoxide.", "content": "The mock accident in first-aid training; poisoning by carbon monoxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982834"}
{"pmid": "20982837", "title": "The value of educational psychology; modern methods and their uses in schools of nursing.", "content": "The value of educational psychology; modern methods and their uses in schools of nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982837"}
{"pmid": "20982838", "title": "A case history of acute idiopathic porphyria.", "content": "A case history of acute idiopathic porphyria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982838"}
{"pmid": "20982839", "title": "HEALTH centre in Africa.", "content": "HEALTH centre in Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982839"}
{"pmid": "20982840", "title": "Doctors meet challenge of cerebral palsy.", "content": "Doctors meet challenge of cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982840"}
{"pmid": "20982842", "title": "Diagnostic hospitals make contribution.", "content": "Diagnostic hospitals make contribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982842"}
{"pmid": "20982841", "title": "Army nurses did superb work.", "content": "Army nurses did superb work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982841"}
{"pmid": "20982843", "title": "Rheumatic fever strikes quickly.", "content": "Rheumatic fever strikes quickly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982843"}
{"pmid": "20982845", "title": "The effect of peripheral stimulation on central acuity.", "content": "The effect of peripheral stimulation on central acuity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982845"}
{"pmid": "20982846", "title": "Clinical results with feincone contact lenses.", "content": "Clinical results with feincone contact lenses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982846"}
{"pmid": "20982844", "title": "The isotonicity of contact lens solution.", "content": "The isotonicity of contact lens solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982844"}
{"pmid": "20982847", "title": "Notes on accommodative training procedures.", "content": "Notes on accommodative training procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982847"}
{"pmid": "20982864", "title": "Toxic amblyopia and color field charting.", "content": "Toxic amblyopia and color field charting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982864"}
{"pmid": "20982865", "title": "Chess and checkers for the blind.", "content": "Chess and checkers for the blind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982865"}
{"pmid": "20982867", "title": "An analysis of braille reading.", "content": "An analysis of braille reading.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982867"}
{"pmid": "20982866", "title": "Social insurance for the blind.", "content": "Social insurance for the blind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982866"}
{"pmid": "20982868", "title": "Opportunities in agriculture for the blind.", "content": "Opportunities in agriculture for the blind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982868"}
{"pmid": "20982869", "title": "SOUNDS changed into visual pattern by new device in Bell Laboratory.", "content": "SOUNDS changed into visual pattern by new device in Bell Laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982869"}
{"pmid": "20982870", "title": "A study of the usefulness of objective measures of mechanical aptitude in guidance programs for the hypacousic.", "content": "A study of the usefulness of objective measures of mechanical aptitude in guidance programs for the hypacousic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982870"}
{"pmid": "20982871", "title": "An oral school in Kentucky one hundred years ago.", "content": "An oral school in Kentucky one hundred years ago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982871"}
{"pmid": "20982885", "title": "A contribution to the theory of the mechanism of the auditory apparatus.", "content": "A contribution to the theory of the mechanism of the auditory apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982885"}
{"pmid": "20982886", "title": "Leeches as temporary endo-parasites in the upper respiratory tract of man.", "content": "Leeches as temporary endo-parasites in the upper respiratory tract of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982886"}
{"pmid": "20982895", "title": "Purpura induced by the initial injection of a pertussis vaccine.", "content": "Purpura induced by the initial injection of a pertussis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982895"}
{"pmid": "20982897", "title": "Tuberculous splenomegaly in children; review of the literature and report of a case.", "content": "Tuberculous splenomegaly in children; review of the literature and report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982897"}
{"pmid": "20982896", "title": "The influence of bronchial asthma on the heart in childhood.", "content": "The influence of bronchial asthma on the heart in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982896"}
{"pmid": "20982899", "title": "Diphtheria; toxic myocarditis; diphtheria with nephritis.", "content": "Diphtheria; toxic myocarditis; diphtheria with nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982899"}
{"pmid": "20982898", "title": "Acute pyelitis in infancy; report of three cases.", "content": "Acute pyelitis in infancy; report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982898"}
{"pmid": "20982911", "title": "DRUGS for treatment of trench mouth.", "content": "DRUGS for treatment of trench mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982911"}
{"pmid": "20982912", "title": "DEVELOPMENTS in tableting.", "content": "DEVELOPMENTS in tableting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982912"}
{"pmid": "20982913", "title": "Hormones in gynecology.", "content": "Hormones in gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982913"}
{"pmid": "20982914", "title": "Opium.", "content": "Opium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982914"}
{"pmid": "20982917", "title": "Diffusion of sulfonamides from emulsified ointment bases.", "content": "Diffusion of sulfonamides from emulsified ointment bases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982917"}
{"pmid": "20982918", "title": "The status of tyrothricin as an antibiotic agent for topical application.", "content": "The status of tyrothricin as an antibiotic agent for topical application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982918"}
{"pmid": "20982919", "title": "Studies on Indian rhubarb; Rheum emodi.", "content": "Studies on Indian rhubarb; Rheum emodi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982919"}
{"pmid": "20982920", "title": "Increase in fatality rate of E. typhosa for white mice by streptomycin.", "content": "Increase in fatality rate of E. typhosa for white mice by streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982920"}
{"pmid": "20982921", "title": "The determination of phenolphthalein in mineral oil emulsions.", "content": "The determination of phenolphthalein in mineral oil emulsions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982921"}
{"pmid": "20982922", "title": "PENICILLIN production.", "content": "PENICILLIN production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982922"}
{"pmid": "20982923", "title": "Compressed tablets.", "content": "Compressed tablets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982923"}
{"pmid": "20982932", "title": "PHYSIOLOGIC and therapeutic aspects of acetylcholine.", "content": "PHYSIOLOGIC and therapeutic aspects of acetylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982932"}
{"pmid": "20982933", "title": "Sources of error in germicidal activity tests with quaternary ammonium compounds.", "content": "Sources of error in germicidal activity tests with quaternary ammonium compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982933"}
{"pmid": "20982934", "title": "Concentrated sprays tested for utility in control of flies and mosquitoes.", "content": "Concentrated sprays tested for utility in control of flies and mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982934"}
{"pmid": "20982935", "title": "Deodorized petroleum base oils.", "content": "Deodorized petroleum base oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982935"}
{"pmid": "20982925", "title": "A polarographic study of alkaloids.", "content": "A polarographic study of alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982925"}
{"pmid": "20982924", "title": "The intestinal excretion of sulphanilylbenzamide in comparison with sulphanilamide, sulphathiazole and sulphaguanidine; its bearing on the efficacy of compounds effective in bacillary dysentery.", "content": "The intestinal excretion of sulphanilylbenzamide in comparison with sulphanilamide, sulphathiazole and sulphaguanidine; its bearing on the efficacy of compounds effective in bacillary dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982924"}
{"pmid": "20982938", "title": "A review of recent progress in ointment therapy.", "content": "A review of recent progress in ointment therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982938"}
{"pmid": "20982927", "title": "Pharmacopoeial kaolin.", "content": "Pharmacopoeial kaolin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982927"}
{"pmid": "20982926", "title": "The characteristics of magnesium trisilicate.", "content": "The characteristics of magnesium trisilicate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982926"}
{"pmid": "20982928", "title": "Investigations on the autoxidation of diethyl ether; autoxidation products and the autoxidation process.", "content": "Investigations on the autoxidation of diethyl ether; autoxidation products and the autoxidation process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982928"}
{"pmid": "20982930", "title": "The action of some drugs on the excised spleen.", "content": "The action of some drugs on the excised spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982930"}
{"pmid": "20982929", "title": "Some observations on the pharmacology of the sphincter of Oddi.", "content": "Some observations on the pharmacology of the sphincter of Oddi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982929"}
{"pmid": "20982931", "title": "Potentiation of insulin hypoglycaemia by nicotinyl taurine (beta-nicotinamidoethanesulphonic acid).", "content": "Potentiation of insulin hypoglycaemia by nicotinyl taurine (beta-nicotinamidoethanesulphonic acid).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982931"}
{"pmid": "20982942", "title": "IS MALARIA coming to your town this summer?", "content": "IS MALARIA coming to your town this summer?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982942"}
{"pmid": "20982939", "title": "Social remedies for social diseases.", "content": "Social remedies for social diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982939"}
{"pmid": "20982941", "title": "INVISIBLE danger; some recently recognized complications of transfusion.", "content": "INVISIBLE danger; some recently recognized complications of transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982941"}
{"pmid": "20982940", "title": "DOCTORS' disease; a vanishing syndrome?", "content": "DOCTORS' disease; a vanishing syndrome?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982940"}
{"pmid": "20982943", "title": "NUTRITIONAL qualities of breast milk.", "content": "NUTRITIONAL qualities of breast milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982943"}
{"pmid": "20982944", "title": "QUINONE VS. AMINE; hypertension and vitamin K.", "content": "QUINONE VS. AMINE; hypertension and vitamin K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982944"}
{"pmid": "20982946", "title": "PENTOTHAL sodium; review of recent literature.", "content": "PENTOTHAL sodium; review of recent literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982946"}
{"pmid": "20982945", "title": "D.D.T. poisoning; a future problem for the practitioner.", "content": "D.D.T. poisoning; a future problem for the practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982945"}
{"pmid": "20982947", "title": "The pressure-volume diagram of the thorax and lung.", "content": "The pressure-volume diagram of the thorax and lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982947"}
{"pmid": "20982948", "title": "Accuracy of indirect determinations of blood pressure in the rat; relation to temperature of plethysmograph and width of cuff.", "content": "Accuracy of indirect determinations of blood pressure in the rat; relation to temperature of plethysmograph and width of cuff.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982948"}
{"pmid": "20982949", "title": "The effect upon the colon of electrical stimulation of forebrain areas in the cat.", "content": "The effect upon the colon of electrical stimulation of forebrain areas in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982949"}
{"pmid": "20982950", "title": "Portal pressure gradients under experimental conditions, including hemorrhagic shock.", "content": "Portal pressure gradients under experimental conditions, including hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982950"}
{"pmid": "20982951", "title": "Performance as related to composition of alveolar air.", "content": "Performance as related to composition of alveolar air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982951"}
{"pmid": "20982952", "title": "A study of oxygen transport in the blood of young and adult domestic ducks.", "content": "A study of oxygen transport in the blood of young and adult domestic ducks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982952"}
{"pmid": "20982953", "title": "Denitrogenation of muscle and fat tissues of the anesthetized cat.", "content": "Denitrogenation of muscle and fat tissues of the anesthetized cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982953"}
{"pmid": "20982954", "title": "Survival of the isolated respiratory center in the young rat as influenced by adrenaline, ephedrine, insulin and glutathione and the relation to glycemia changes.", "content": "Survival of the isolated respiratory center in the young rat as influenced by adrenaline, ephedrine, insulin and glutathione and the relation to glycemia changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982954"}
{"pmid": "20982955", "title": "Cholinesterases in degenerating and regenerating peripheral nerves.", "content": "Cholinesterases in degenerating and regenerating peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982955"}
{"pmid": "20982956", "title": "The differentiation of potassium from other agents associated with the toxic effects of tourniquet shock.", "content": "The differentiation of potassium from other agents associated with the toxic effects of tourniquet shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982956"}
{"pmid": "20982957", "title": "Body cooling of rats, rabbits and dogs following immersion in water, with a few observations on man.", "content": "Body cooling of rats, rabbits and dogs following immersion in water, with a few observations on man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982957"}
{"pmid": "20982958", "title": "Biological energy transformations during shock as shown by tissue analyses.", "content": "Biological energy transformations during shock as shown by tissue analyses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982958"}
{"pmid": "20982959", "title": "The rôle of sensory and motor cortical projections in escape and avoidance conditioning in dogs.", "content": "The rôle of sensory and motor cortical projections in escape and avoidance conditioning in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982959"}
{"pmid": "20982960", "title": "The enterohepatic circulation of foreign bile acids; the circulation of cholates in hogs with biliary fistulae.", "content": "The enterohepatic circulation of foreign bile acids; the circulation of cholates in hogs with biliary fistulae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982960"}
{"pmid": "20982961", "title": "Venous pressure changes associated with positive intrapulmonary pressures; their relationship to the distensibility of the lung.", "content": "Venous pressure changes associated with positive intrapulmonary pressures; their relationship to the distensibility of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982961"}
{"pmid": "20982968", "title": "Sympathomimetic amines: the relation of structure to their action and inactivation.", "content": "Sympathomimetic amines: the relation of structure to their action and inactivation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982968"}
{"pmid": "20982969", "title": "The fixation of carbon dioxide and the inter-relationships of the tricarboxylic acid cycle.", "content": "The fixation of carbon dioxide and the inter-relationships of the tricarboxylic acid cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982969"}
{"pmid": "20982970", "title": "The effect of body temperature on drug action.", "content": "The effect of body temperature on drug action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982970"}
{"pmid": "20982963", "title": "The viability of isolated nerve fragments and its modification by methylene blue.", "content": "The viability of isolated nerve fragments and its modification by methylene blue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982963"}
{"pmid": "20982965", "title": "A neglected factor in studies of potassium distribution in relation to the resting potential of nerve.", "content": "A neglected factor in studies of potassium distribution in relation to the resting potential of nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982965"}
{"pmid": "20982971", "title": "Lipins and lipidoses.", "content": "Lipins and lipidoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982971"}
{"pmid": "20982972", "title": "Organizers in development and the organizer concept.", "content": "Organizers in development and the organizer concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982972"}
{"pmid": "20982973", "title": "The thromboplastic effects of tissue extracts and their inhibition by immune sera.", "content": "The thromboplastic effects of tissue extracts and their inhibition by immune sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982973"}
{"pmid": "20982974", "title": "Innate and acquired behavior affecting the aggregation of fishes.", "content": "Innate and acquired behavior affecting the aggregation of fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982974"}
{"pmid": "20982964", "title": "Elasticity of muscle in relation to actively developed twitch tension.", "content": "Elasticity of muscle in relation to actively developed twitch tension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982964"}
{"pmid": "20982967", "title": "Reversible heat inactivation of Cypridina luciferase.", "content": "Reversible heat inactivation of Cypridina luciferase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982967"}
{"pmid": "20982962", "title": "True cholinestererases with pronounced resistance to eserine.", "content": "True cholinestererases with pronounced resistance to eserine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982962"}
{"pmid": "20982975", "title": "The reactions of Culex larvae and pupae to gravity, light, and mechanical shock.", "content": "The reactions of Culex larvae and pupae to gravity, light, and mechanical shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982975"}
{"pmid": "20982966", "title": "The effect of adenosinetriphosphate on the viscosity of actin solutions.", "content": "The effect of adenosinetriphosphate on the viscosity of actin solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982966"}
{"pmid": "20982976", "title": "Effect of weak alternating-current shocks upon the division of Stylonychia pustulata (Ehrenberg).", "content": "Effect of weak alternating-current shocks upon the division of Stylonychia pustulata (Ehrenberg).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982976"}
{"pmid": "20982977", "title": "The effects of noise on school children; an interpretive digest and recommendation.", "content": "The effects of noise on school children; an interpretive digest and recommendation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982977"}
{"pmid": "20982978", "title": "Correlates of handedness among college freshmen.", "content": "Correlates of handedness among college freshmen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982978"}
{"pmid": "20982979", "title": "The validity of certain objective techniques for measuring the ability to translate German into English.", "content": "The validity of certain objective techniques for measuring the ability to translate German into English.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982979"}
{"pmid": "20982980", "title": "Regression lines for estimating intelligence quotients and American Council examination scores.", "content": "Regression lines for estimating intelligence quotients and American Council examination scores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982980"}
{"pmid": "20982981", "title": "Note on a comment on the correction of reliability coefficients for restriction of range.", "content": "Note on a comment on the correction of reliability coefficients for restriction of range.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982981"}
{"pmid": "20982982", "title": "Studies of motor functions in schizophrenia; steadiness.", "content": "Studies of motor functions in schizophrenia; steadiness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982982"}
{"pmid": "20982983", "title": "The influence of emotional subject matter on logical reasoning.", "content": "The influence of emotional subject matter on logical reasoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982983"}
{"pmid": "20982984", "title": "An exploratory study of discrimination of composer style.", "content": "An exploratory study of discrimination of composer style.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982984"}
{"pmid": "20982985", "title": "Discrimination of ambivalent cue stimuli by macaque monkeys.", "content": "Discrimination of ambivalent cue stimuli by macaque monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982985"}
{"pmid": "20982986", "title": "A comparison of learning and retention of materials presented visually and auditorially.", "content": "A comparison of learning and retention of materials presented visually and auditorially.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982986"}
{"pmid": "20982987", "title": "The Nebraska Army Alpha Revision and the comparative strength of factors V,N, and R in nursing students.", "content": "The Nebraska Army Alpha Revision and the comparative strength of factors V,N, and R in nursing students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982987"}
{"pmid": "20982988", "title": "Brain sensitization in personality disorders.", "content": "Brain sensitization in personality disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982988"}
{"pmid": "20982989", "title": "Relaxation in psychotherapy.", "content": "Relaxation in psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982989"}
{"pmid": "20982990", "title": "A memory drum for paired associate learning.", "content": "A memory drum for paired associate learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982990"}
{"pmid": "20982997", "title": "Replanning Britain's health services.", "content": "Replanning Britain's health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982997"}
{"pmid": "20982998", "title": "Education and the extension of public health services.", "content": "Education and the extension of public health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982998"}
{"pmid": "20982999", "title": "Observations in an outbreak of Streptococcus haemolyticus infection at an R.C.A.F. station.", "content": "Observations in an outbreak of Streptococcus haemolyticus infection at an R.C.A.F. station.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20982999"}
{"pmid": "20983000", "title": "Interim report on the activities of the Committee on Joint Causes of Death.", "content": "Interim report on the activities of the Committee on Joint Causes of Death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983000"}
{"pmid": "20983001", "title": "Public health nursing in the control of syphilis and gonorrhoea; how the public health nurse can assist the medical officer of health.", "content": "Public health nursing in the control of syphilis and gonorrhoea; how the public health nurse can assist the medical officer of health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983001"}
{"pmid": "20983002", "title": "A review of the uses of the insecticide DDT in the control of insect pests affecting humans.", "content": "A review of the uses of the insecticide DDT in the control of insect pests affecting humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983002"}
{"pmid": "20983003", "title": "MOBILE dental unit now operating.", "content": "MOBILE dental unit now operating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983003"}
{"pmid": "20983004", "title": "Permanent enrichment of flour and bread.", "content": "Permanent enrichment of flour and bread.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983004"}
{"pmid": "20983005", "title": "Chronological age versus physiological age.", "content": "Chronological age versus physiological age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983005"}
{"pmid": "20983006", "title": "Serological tests for syphilis in Connecticut 1945.", "content": "Serological tests for syphilis in Connecticut 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983006"}
{"pmid": "20983007", "title": "An experimental study on cellular immunity in Pasteurella pestis infection.", "content": "An experimental study on cellular immunity in Pasteurella pestis infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983007"}
{"pmid": "20983008", "title": "The natural ventilation of unheated closed rooms.", "content": "The natural ventilation of unheated closed rooms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983008"}
{"pmid": "20983009", "title": "Some methods of measuring ventilation.", "content": "Some methods of measuring ventilation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983009"}
{"pmid": "20983010", "title": "Bactericidal effects of the partial irradiation of a room with ultra-violet light.", "content": "Bactericidal effects of the partial irradiation of a room with ultra-violet light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983010"}
{"pmid": "20983011", "title": "A localized outbreak of Salmonella food poisoning apparently transmitted by a hen's egg.", "content": "A localized outbreak of Salmonella food poisoning apparently transmitted by a hen's egg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983011"}
{"pmid": "20983012", "title": "A critical examination of the organism described as Bacillus wakefield.", "content": "A critical examination of the organism described as Bacillus wakefield.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983012"}
{"pmid": "20983013", "title": "The incidence of natural diphtheria antitoxin in horses; its influence on the results of antigenic stimulus.", "content": "The incidence of natural diphtheria antitoxin in horses; its influence on the results of antigenic stimulus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983013"}
{"pmid": "20983014", "title": "The epidemic curve for mumps.", "content": "The epidemic curve for mumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983014"}
{"pmid": "20983015", "title": "Analysis of meals served in Surrey school canteens.", "content": "Analysis of meals served in Surrey school canteens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983015"}
{"pmid": "20983016", "title": "Iodine as an aerial disinfectant.", "content": "Iodine as an aerial disinfectant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983016"}
{"pmid": "20983017", "title": "The statistical treatment of measurements of the carcinogenic properties of tars and mineral oils.", "content": "The statistical treatment of measurements of the carcinogenic properties of tars and mineral oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983017"}
{"pmid": "20983018", "title": "The problem family in the Netherlands.", "content": "The problem family in the Netherlands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983018"}
{"pmid": "20983019", "title": "MEDICAL treatment of school children.", "content": "MEDICAL treatment of school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983019"}
{"pmid": "20983020", "title": "The prevention and treatment of tinea pedis.", "content": "The prevention and treatment of tinea pedis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983020"}
{"pmid": "20983021", "title": "Notified measles, 1940-45.", "content": "Notified measles, 1940-45.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983021"}
{"pmid": "20983022", "title": "Notified measles, 1940-1945; a note on the serial batch fatality rates.", "content": "Notified measles, 1940-1945; a note on the serial batch fatality rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983022"}
{"pmid": "20983023", "title": "The maintenance of a strain of Plasmodium vivax through man and mosquito over a period of 21 years.", "content": "The maintenance of a strain of Plasmodium vivax through man and mosquito over a period of 21 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983023"}
{"pmid": "20983024", "title": "The laboratory diagnosis of smallpox.", "content": "The laboratory diagnosis of smallpox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983024"}
{"pmid": "20983025", "title": "An outbreak of gastro-enteritis due to Salm. thompson.", "content": "An outbreak of gastro-enteritis due to Salm. thompson.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983025"}
{"pmid": "20983027", "title": "The Teviot report.", "content": "The Teviot report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983027"}
{"pmid": "20983026", "title": "Some problems in rural public health.", "content": "Some problems in rural public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983026"}
{"pmid": "20983028", "title": "The treatment of cancer.", "content": "The treatment of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983028"}
{"pmid": "20983029", "title": "Training public health workers.", "content": "Training public health workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983029"}
{"pmid": "20983030", "title": "The nature of the soluble antigen from typhus rickettsiae.", "content": "The nature of the soluble antigen from typhus rickettsiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983030"}
{"pmid": "20983031", "title": "Antibacterial action of penicillin, penicillin X, and streptomycin on Hemophilus influenzae.", "content": "Antibacterial action of penicillin, penicillin X, and streptomycin on Hemophilus influenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983031"}
{"pmid": "20983033", "title": "CHARTER for school health; a review.", "content": "CHARTER for school health; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983033"}
{"pmid": "20983032", "title": "A method for the preparation of tsutsugamushi (scrub typhus) antigen from infected yolk sacs.", "content": "A method for the preparation of tsutsugamushi (scrub typhus) antigen from infected yolk sacs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983032"}
{"pmid": "20983034", "title": "Outbreak of Q fever in the United States.", "content": "Outbreak of Q fever in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983034"}
{"pmid": "20983035", "title": "The status of required physical education in colleges and universities of the United States.", "content": "The status of required physical education in colleges and universities of the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983035"}
{"pmid": "20983036", "title": "Anthropometric characteristics and physical fitness.", "content": "Anthropometric characteristics and physical fitness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983036"}
{"pmid": "20983037", "title": "Relation between leg-lift and sit-up.", "content": "Relation between leg-lift and sit-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983037"}
{"pmid": "20983038", "title": "An analysis of the physical education programs of the Minnesota secondary schools.", "content": "An analysis of the physical education programs of the Minnesota secondary schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983038"}
{"pmid": "20983039", "title": "A comparative analysis of secondary-school boys' and girls' character and personality traits in physical education classes.", "content": "A comparative analysis of secondary-school boys' and girls' character and personality traits in physical education classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983039"}
{"pmid": "20983041", "title": "Standardization of a badminton knowledge test for college women.", "content": "Standardization of a badminton knowledge test for college women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983041"}
{"pmid": "20983040", "title": "A differential analysis of sit-ups for strength and muscular endurance.", "content": "A differential analysis of sit-ups for strength and muscular endurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983040"}
{"pmid": "20983046", "title": "Onchocerciasis.", "content": "Onchocerciasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983046"}
{"pmid": "20983054", "title": "Plain aeration of sewage.", "content": "Plain aeration of sewage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983054"}
{"pmid": "20983055", "title": "Effect of food wastes on sewers and sewage treatment.", "content": "Effect of food wastes on sewers and sewage treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983055"}
{"pmid": "20983056", "title": "Treatment of cyanide and acid plating wastes.", "content": "Treatment of cyanide and acid plating wastes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983056"}
{"pmid": "20983057", "title": "REPORT of procedure for the handling of industrial wastes.", "content": "REPORT of procedure for the handling of industrial wastes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983057"}
{"pmid": "20983058", "title": "The distribution of radiation in the atomic bombing of Nagasaki.", "content": "The distribution of radiation in the atomic bombing of Nagasaki.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983058"}
{"pmid": "20983059", "title": "Supervoltage radiation; a review of the cases treated during an eight year period (1937-1944 inclusive).", "content": "Supervoltage radiation; a review of the cases treated during an eight year period (1937-1944 inclusive).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983059"}
{"pmid": "20983060", "title": "The management of malignant tumors of the testis.", "content": "The management of malignant tumors of the testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983060"}
{"pmid": "20983061", "title": "Intrapulmonary air pressure and its relation to pulmonary capillary flow.", "content": "Intrapulmonary air pressure and its relation to pulmonary capillary flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983061"}
{"pmid": "20983063", "title": "Diagnostic problems in fractures of the foot and ankle.", "content": "Diagnostic problems in fractures of the foot and ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983063"}
{"pmid": "20983062", "title": "Emphysematous gastritis.", "content": "Emphysematous gastritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983062"}
{"pmid": "20983065", "title": "Heat capacities of roentgen-ray tubes; with particular reference to use for mass survey work.", "content": "Heat capacities of roentgen-ray tubes; with particular reference to use for mass survey work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983065"}
{"pmid": "20983064", "title": "Some procedures facilitating roentgenologic interpretation in an induction station.", "content": "Some procedures facilitating roentgenologic interpretation in an induction station.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983064"}
{"pmid": "20983066", "title": "An analysis of the physical factors controlling the diagnostic quality of roentgen images; contrast and the film contrast factor.", "content": "An analysis of the physical factors controlling the diagnostic quality of roentgen images; contrast and the film contrast factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983066"}
{"pmid": "20983067", "title": "A recent visit with French radiologists.", "content": "A recent visit with French radiologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983067"}
{"pmid": "20983068", "title": "From the memoirs of a student in Röntgen's laboratory in WArzburg half a century ago.", "content": "From the memoirs of a student in Röntgen's laboratory in WArzburg half a century ago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983068"}
{"pmid": "20983069", "title": "Some uses for the tomograph.", "content": "Some uses for the tomograph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983069"}
{"pmid": "20983070", "title": "The pneumodigraph.", "content": "The pneumodigraph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983070"}
{"pmid": "20983071", "title": "Radiography; an essential aid in obstetrical and gynaecological practice.", "content": "Radiography; an essential aid in obstetrical and gynaecological practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983071"}
{"pmid": "20983072", "title": "The decline of the male radiographer.", "content": "The decline of the male radiographer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983072"}
{"pmid": "20983073", "title": "The value of orchiectomy in the treatment of carcinoma of the male breast.", "content": "The value of orchiectomy in the treatment of carcinoma of the male breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983073"}
{"pmid": "20983074", "title": "The problem of secondary infection in carcinoma of the cervix.", "content": "The problem of secondary infection in carcinoma of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983074"}
{"pmid": "20983076", "title": "Roentgen diagnosis of knee-joint effusion.", "content": "Roentgen diagnosis of knee-joint effusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983076"}
{"pmid": "20983075", "title": "Indications and limitations of transvaginal roentgen therapy for cancer of the cervix.", "content": "Indications and limitations of transvaginal roentgen therapy for cancer of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983075"}
{"pmid": "20983077", "title": "Extrapleural pneumothorax in the treatment of pulmonary tuberculosis.", "content": "Extrapleural pneumothorax in the treatment of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983077"}
{"pmid": "20983079", "title": "A comparative clinical investigation of cholecystographic preparations.", "content": "A comparative clinical investigation of cholecystographic preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983079"}
{"pmid": "20983078", "title": "The so-called retarded or occult fractures.", "content": "The so-called retarded or occult fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983078"}
{"pmid": "20983080", "title": "March fracture.", "content": "March fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983080"}
{"pmid": "20983081", "title": "Hiatus hernia of the stomach as a source of gastro-intestinal bleeding.", "content": "Hiatus hernia of the stomach as a source of gastro-intestinal bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983081"}
{"pmid": "20983082", "title": "Lymphoblastoma of the kidney.", "content": "Lymphoblastoma of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983082"}
{"pmid": "20983083", "title": "Paragonimus westermanii.", "content": "Paragonimus westermanii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983083"}
{"pmid": "20983084", "title": "Two cases of spinal anomaly, best demonstrated by laminagraphy.", "content": "Two cases of spinal anomaly, best demonstrated by laminagraphy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983084"}
{"pmid": "20983085", "title": "Spontaneous renocolic fistula.", "content": "Spontaneous renocolic fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983085"}
{"pmid": "20983086", "title": "Bronchial asthma; new etiologic and therapeutic approach.", "content": "Bronchial asthma; new etiologic and therapeutic approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983086"}
{"pmid": "20983090", "title": "Appendicitis in combat zone as seen in a field hospital.", "content": "Appendicitis in combat zone as seen in a field hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983090"}
{"pmid": "20983091", "title": "A method of continuous brachial plexus block.", "content": "A method of continuous brachial plexus block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983091"}
{"pmid": "20983092", "title": "Indications and advantages of complete abdominal hysterectomy versus incomplete hysterectomy.", "content": "Indications and advantages of complete abdominal hysterectomy versus incomplete hysterectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983092"}
{"pmid": "20983093", "title": "Abdominoperineal proctosigmoidectomy for cancer of rectum; conclusions based on five years' experience.", "content": "Abdominoperineal proctosigmoidectomy for cancer of rectum; conclusions based on five years' experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983093"}
{"pmid": "20983094", "title": "Traumatic aneurysms of the extremities.", "content": "Traumatic aneurysms of the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983094"}
{"pmid": "20983095", "title": "Genital tuberculosis in women.", "content": "Genital tuberculosis in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983095"}
{"pmid": "20983096", "title": "Bilateral Petit's hernia and an anterior sacral meningocele occurring in the same patient.", "content": "Bilateral Petit's hernia and an anterior sacral meningocele occurring in the same patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983096"}
{"pmid": "20983097", "title": "Trauma to the abdomen.", "content": "Trauma to the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983097"}
{"pmid": "20983098", "title": "Varicocele.", "content": "Varicocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983098"}
{"pmid": "20983099", "title": "Management of intertrochanteric fractures of the femur by skeletal traction with the beaded Kirschner wire.", "content": "Management of intertrochanteric fractures of the femur by skeletal traction with the beaded Kirschner wire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983099"}
{"pmid": "20983100", "title": "Inguinal herniorrhaphy from the intra-abdominal perspective; retention of the sac and intact external ring, and a means for proving the adequacy of the repair.", "content": "Inguinal herniorrhaphy from the intra-abdominal perspective; retention of the sac and intact external ring, and a means for proving the adequacy of the repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983100"}
{"pmid": "20983101", "title": "A device to simplify end-to end anastomosis of the large bowel; the elimination of unequal diameters of the two segments to be anastomosed.", "content": "A device to simplify end-to end anastomosis of the large bowel; the elimination of unequal diameters of the two segments to be anastomosed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983101"}
{"pmid": "20983102", "title": "Total gastrectomy for complete carcinomatous involvement of the stomach.", "content": "Total gastrectomy for complete carcinomatous involvement of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983102"}
{"pmid": "20983103", "title": "Multiple argentaffin tumors (carcinoids) of the rectum.", "content": "Multiple argentaffin tumors (carcinoids) of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983103"}
{"pmid": "20983104", "title": "Reconstruction of thumb.", "content": "Reconstruction of thumb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983104"}
{"pmid": "20983105", "title": "Osteomyelitis of the frontal bone and subdural empyema with recovery.", "content": "Osteomyelitis of the frontal bone and subdural empyema with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983105"}
{"pmid": "20983106", "title": "Hyperparathyroidism due to parathyroid adenoma.", "content": "Hyperparathyroidism due to parathyroid adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983106"}
{"pmid": "20983107", "title": "Streptomycin in the treatment of surgical infections; report of experiences with its use.", "content": "Streptomycin in the treatment of surgical infections; report of experiences with its use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983107"}
{"pmid": "20983108", "title": "Physiologic considerations in the care of patients with varicose veins.", "content": "Physiologic considerations in the care of patients with varicose veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983108"}
{"pmid": "20983109", "title": "Treatment of an unusual subdural hydroma (external hydrocephalus).", "content": "Treatment of an unusual subdural hydroma (external hydrocephalus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983109"}
{"pmid": "20983111", "title": "Treatment of fractures of the carpal scaphoid; a report of sixty-four cases.", "content": "Treatment of fractures of the carpal scaphoid; a report of sixty-four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983111"}
{"pmid": "20983110", "title": "Diagnosis of acute appendicitis in the presence of diarrhea.", "content": "Diagnosis of acute appendicitis in the presence of diarrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983110"}
{"pmid": "20983112", "title": "Penicillin ointment-impregnated gauze in the local treatment of infections.", "content": "Penicillin ointment-impregnated gauze in the local treatment of infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983112"}
{"pmid": "20983113", "title": "A surgical specimen consisting of a partially developed parasitic fetus.", "content": "A surgical specimen consisting of a partially developed parasitic fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983113"}
{"pmid": "20983114", "title": "Review of urologic surgery.", "content": "Review of urologic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983114"}
{"pmid": "20983134", "title": "Observations on radical surgery for lesions of the pancreas.", "content": "Observations on radical surgery for lesions of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983134"}
{"pmid": "20983135", "title": "Primary suture of nerves.", "content": "Primary suture of nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983135"}
{"pmid": "20983136", "title": "A clinical and pathologic study of the kidney in patients with thermal burns.", "content": "A clinical and pathologic study of the kidney in patients with thermal burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983136"}
{"pmid": "20983137", "title": "A new method of treatment for severe fractures of the os calcis; a preliminary report.", "content": "A new method of treatment for severe fractures of the os calcis; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983137"}
{"pmid": "20983138", "title": "Large retroperitoneal metastasis from a so-called carcinoid of the small intestine.", "content": "Large retroperitoneal metastasis from a so-called carcinoid of the small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983138"}
{"pmid": "20983139", "title": "Intrathoracic tumors of the sympathetic nervous system.", "content": "Intrathoracic tumors of the sympathetic nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983139"}
{"pmid": "20983140", "title": "Pilonidal cyst; analysis of 100 consecutive cases, emphasizing treatment by radical excision, primary closure and penicillin therapy.", "content": "Pilonidal cyst; analysis of 100 consecutive cases, emphasizing treatment by radical excision, primary closure and penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983140"}
{"pmid": "20983141", "title": "The lateral aberrant thyroid.", "content": "The lateral aberrant thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983141"}
{"pmid": "20983142", "title": "Urinary incontinence due to bilateral ectopic ureters.", "content": "Urinary incontinence due to bilateral ectopic ureters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983142"}
{"pmid": "20983143", "title": "Studies on exophthalmos produced by thyrotropic hormone; further study of changes induced in fat by thyrotropic hormone (tissue reactions associated with exophthalmos).", "content": "Studies on exophthalmos produced by thyrotropic hormone; further study of changes induced in fat by thyrotropic hormone (tissue reactions associated with exophthalmos).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983143"}
{"pmid": "20983144", "title": "Spontaneous gastrointestinal biliary fistulas.", "content": "Spontaneous gastrointestinal biliary fistulas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983144"}
{"pmid": "20983145", "title": "Ruptures of malarial spleens unassociated with external trauma.", "content": "Ruptures of malarial spleens unassociated with external trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983145"}
{"pmid": "20983146", "title": "Experimental surgical pulmonary collapse.", "content": "Experimental surgical pulmonary collapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983146"}
{"pmid": "20983148", "title": "Burns; colective review.", "content": "Burns; colective review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983148"}
{"pmid": "20983147", "title": "The Rh factor-serologic background and clinical application.", "content": "The Rh factor-serologic background and clinical application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983147"}
{"pmid": "20983149", "title": "Sex difference in the size of the thymus in guinea-pigs.", "content": "Sex difference in the size of the thymus in guinea-pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983149"}
{"pmid": "20983152", "title": "Quantitative investigations on the anterior pituitary body of castrated rats with reference to the absolute cell conditions and their significance.", "content": "Quantitative investigations on the anterior pituitary body of castrated rats with reference to the absolute cell conditions and their significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983152"}
{"pmid": "20983157", "title": "Experiments into the action of testosterone propionate on the kidneys of male rabbits.", "content": "Experiments into the action of testosterone propionate on the kidneys of male rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983157"}
{"pmid": "20983162", "title": "Sulfathiazole as a medication for American foul brood disease of honeybees.", "content": "Sulfathiazole as a medication for American foul brood disease of honeybees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983162"}
{"pmid": "20983163", "title": "Diatomaceous diluents for dusts.", "content": "Diatomaceous diluents for dusts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983163"}
{"pmid": "20983164", "title": "Chemical methods for analysis of dichloro-diphenyltrichloroethane (DDT).", "content": "Chemical methods for analysis of dichloro-diphenyltrichloroethane (DDT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983164"}
{"pmid": "20983165", "title": "DDT on peaches; three years field experiments.", "content": "DDT on peaches; three years field experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983165"}
{"pmid": "20983166", "title": "DDT and other new insecticides for control of cauliflower worms on Long Island.", "content": "DDT and other new insecticides for control of cauliflower worms on Long Island.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983166"}
{"pmid": "20983167", "title": "DDT as a control for the pea aphid.", "content": "DDT as a control for the pea aphid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983167"}
{"pmid": "20983168", "title": "DDT to control potato aphids.", "content": "DDT to control potato aphids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983168"}
{"pmid": "20983170", "title": "DDT and ryanex to control oriental fruit moth; their effect upon parasite populations.", "content": "DDT and ryanex to control oriental fruit moth; their effect upon parasite populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983170"}
{"pmid": "20983169", "title": "DDT for codling moth control in western New York in 1945.", "content": "DDT for codling moth control in western New York in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983169"}
{"pmid": "20983171", "title": "New formulations of aerosols dispersed by liquefied gases.", "content": "New formulations of aerosols dispersed by liquefied gases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983171"}
{"pmid": "20983172", "title": "DDT preparations for control of the pea aphid.", "content": "DDT preparations for control of the pea aphid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983172"}
{"pmid": "20983173", "title": "Particle-size distribution in liquefied-gas aerosols.", "content": "Particle-size distribution in liquefied-gas aerosols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983173"}
{"pmid": "20983174", "title": "The thermal aerosol for generator for large scale application of DDT and other insecticides.", "content": "The thermal aerosol for generator for large scale application of DDT and other insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983174"}
{"pmid": "20983175", "title": "Control of the American dog tick, a vector of Rocky Mountain spotted fever; preliminary tests.", "content": "Control of the American dog tick, a vector of Rocky Mountain spotted fever; preliminary tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983175"}
{"pmid": "20983176", "title": "DDT thermal aerosol fogs to control clothes moths in a wool storage warehouse.", "content": "DDT thermal aerosol fogs to control clothes moths in a wool storage warehouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983176"}
{"pmid": "20983177", "title": "Rate of development of milky disease in Japanese beetle populations.", "content": "Rate of development of milky disease in Japanese beetle populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983177"}
{"pmid": "20983178", "title": "Eradication of boxwood leafminer and the boxwood psyllid.", "content": "Eradication of boxwood leafminer and the boxwood psyllid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983178"}
{"pmid": "20983179", "title": "The control of mites on apple trees sprayed with DDT.", "content": "The control of mites on apple trees sprayed with DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983179"}
{"pmid": "20983181", "title": "Individual comparisons of grouped data by ranking methods.", "content": "Individual comparisons of grouped data by ranking methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983181"}
{"pmid": "20983180", "title": "Compatibility of DDT and fungicides on potatoes.", "content": "Compatibility of DDT and fungicides on potatoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983180"}
{"pmid": "20983182", "title": "Two industry problems caused by release of DDT.", "content": "Two industry problems caused by release of DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983182"}
{"pmid": "20983183", "title": "DDT for control of a book louse.", "content": "DDT for control of a book louse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983183"}
{"pmid": "20983192", "title": "Studies on the pharmacology of cholic acid.", "content": "Studies on the pharmacology of cholic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983192"}
{"pmid": "20983193", "title": "Rôle of methemoglobinemia in protection against and treatment of inhalation poisoning by HCN and CNCl.", "content": "Rôle of methemoglobinemia in protection against and treatment of inhalation poisoning by HCN and CNCl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983193"}
{"pmid": "20983184", "title": "Proposals concerning the nomenclature of the gill fungi including a list of proposed lectotypes and genera conservanda.", "content": "Proposals concerning the nomenclature of the gill fungi including a list of proposed lectotypes and genera conservanda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983184"}
{"pmid": "20983194", "title": "Curative effect of plasmoquin in Plasmodium lophurae infections.", "content": "Curative effect of plasmoquin in Plasmodium lophurae infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983194"}
{"pmid": "20983196", "title": "Synergisms and antagonisms between physostigmine and di-iso-propyl fluorophosphate.", "content": "Synergisms and antagonisms between physostigmine and di-iso-propyl fluorophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983196"}
{"pmid": "20983195", "title": "The chronic toxicity of di-isopropyl fluorophosphate in dogs, monkeys and rats.", "content": "The chronic toxicity of di-isopropyl fluorophosphate in dogs, monkeys and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983195"}
{"pmid": "20983197", "title": "The effect of coumingine on the contractile force of isolated mammalian cardiac muscle.", "content": "The effect of coumingine on the contractile force of isolated mammalian cardiac muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983197"}
{"pmid": "20983185", "title": "Studies on some fungi from northwestern Wyoming; fungi imperfecti.", "content": "Studies on some fungi from northwestern Wyoming; fungi imperfecti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983185"}
{"pmid": "20983198", "title": "On the expectorant action of cholinergic drugs.", "content": "On the expectorant action of cholinergic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983198"}
{"pmid": "20983186", "title": "Aerosol OT in the preparation of microscopic mounts of fungi.", "content": "Aerosol OT in the preparation of microscopic mounts of fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983186"}
{"pmid": "20983199", "title": "The effects of di-isopropyl fluorophosphate upon normal and glaucomatous eyes.", "content": "The effects of di-isopropyl fluorophosphate upon normal and glaucomatous eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983199"}
{"pmid": "20983200", "title": "A preliminary survey of certain lactone antibiotics.", "content": "A preliminary survey of certain lactone antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983200"}
{"pmid": "20983201", "title": "Inhibitory potency of sympathomimetic amines and their ganglionic inhibitory action.", "content": "Inhibitory potency of sympathomimetic amines and their ganglionic inhibitory action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983201"}
{"pmid": "20983202", "title": "The protective action of atabrine against chloroform-adrenaline ventricular fibrillation.", "content": "The protective action of atabrine against chloroform-adrenaline ventricular fibrillation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983202"}
{"pmid": "20983203", "title": "Toxicity of certain halogenated aliphatic acids for mice.", "content": "Toxicity of certain halogenated aliphatic acids for mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983203"}
{"pmid": "20983204", "title": "Relation of structure to activity in a new series of sympatholytic agents.", "content": "Relation of structure to activity in a new series of sympatholytic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983204"}
{"pmid": "20983205", "title": "Effect of anti-reticular cytotoxic serum on the healing of experimental wounds in rats.", "content": "Effect of anti-reticular cytotoxic serum on the healing of experimental wounds in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983205"}
{"pmid": "20983206", "title": "The effect of phloridzin on the renal excretion of mercury.", "content": "The effect of phloridzin on the renal excretion of mercury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983206"}
{"pmid": "20983207", "title": "Chemotherapy of Plasmodium knowlesi infections in Macaca mulatta monkeys.", "content": "Chemotherapy of Plasmodium knowlesi infections in Macaca mulatta monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983207"}
{"pmid": "20983208", "title": "Dose and intensity of action and elimination of prostigmine.", "content": "Dose and intensity of action and elimination of prostigmine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983208"}
{"pmid": "20983209", "title": "The response of fatigued myocardium to known concentrations of a cardiac glycoside.", "content": "The response of fatigued myocardium to known concentrations of a cardiac glycoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983209"}
{"pmid": "20983210", "title": "The action of 1,1-diphenyl-1-(dimethylaminoisopropyl)-butanone-2, a potent analgesic agent.", "content": "The action of 1,1-diphenyl-1-(dimethylaminoisopropyl)-butanone-2, a potent analgesic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983210"}
{"pmid": "20983211", "title": "Pharmacological studies of anti-histamine compounds.", "content": "Pharmacological studies of anti-histamine compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983211"}
{"pmid": "20983212", "title": "Determination of salicylate fractions in urine following the administration of salicylates.", "content": "Determination of salicylate fractions in urine following the administration of salicylates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983212"}
{"pmid": "20983213", "title": "The influence of streptomycin and promin on the proliferation of tubercle bacilli in the tissues of the albino rat.", "content": "The influence of streptomycin and promin on the proliferation of tubercle bacilli in the tissues of the albino rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983213"}
{"pmid": "20983214", "title": "Detection of oxidation-reduction by alkaline solutions of methylene blue and orcein.", "content": "Detection of oxidation-reduction by alkaline solutions of methylene blue and orcein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983214"}
{"pmid": "20983215", "title": "Depression of metabolism and temperature in traumatic shock as evidence of a toxic factor.", "content": "Depression of metabolism and temperature in traumatic shock as evidence of a toxic factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983215"}
{"pmid": "20983216", "title": "Pamaquin; suppressive antimalarial activity in vivax and falciparum malaria.", "content": "Pamaquin; suppressive antimalarial activity in vivax and falciparum malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983216"}
{"pmid": "20983217", "title": "Studies on the fate of tri-p-anisyl chloroethylene and hexestrol.", "content": "Studies on the fate of tri-p-anisyl chloroethylene and hexestrol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983217"}
{"pmid": "20983218", "title": "Chemotherapeutic studies on experimental leishmaniasis.", "content": "Chemotherapeutic studies on experimental leishmaniasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983218"}
{"pmid": "20983220", "title": "Toxicity of methylamino-iso-octene (octin).", "content": "Toxicity of methylamino-iso-octene (octin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983220"}
{"pmid": "20983219", "title": "The relation between the chemical structure of DDT and its toxicity with oral administration to mice.", "content": "The relation between the chemical structure of DDT and its toxicity with oral administration to mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983219"}
{"pmid": "20983221", "title": "The effect of cyanide on the electrocardiogram of man.", "content": "The effect of cyanide on the electrocardiogram of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983221"}
{"pmid": "20983223", "title": "Cinchona alkaloids; suppressive antimalarial activity of cinchonine carbostyril.", "content": "Cinchona alkaloids; suppressive antimalarial activity of cinchonine carbostyril.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983223"}
{"pmid": "20983222", "title": "Effects of a cycle of morphine addiction on conditioned responses and experimental neuroses in dogs.", "content": "Effects of a cycle of morphine addiction on conditioned responses and experimental neuroses in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983222"}
{"pmid": "20983226", "title": "Intrasplenic ovarian grafts in the guinea pig and the problem of neoplastic reactions of the graft.", "content": "Intrasplenic ovarian grafts in the guinea pig and the problem of neoplastic reactions of the graft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983226"}
{"pmid": "20983227", "title": "Evidences of increase in the capacity of the pulmonary arteries and veins of dogs, cats and rabbits during inflation of the freshly excised lung.", "content": "Evidences of increase in the capacity of the pulmonary arteries and veins of dogs, cats and rabbits during inflation of the freshly excised lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983227"}
{"pmid": "20983232", "title": "Surgical anatomy; Langer's muscle of the axilla.", "content": "Surgical anatomy; Langer's muscle of the axilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983232"}
{"pmid": "20983233", "title": "Radiographic vignettes; the supracondylar process.", "content": "Radiographic vignettes; the supracondylar process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983233"}
{"pmid": "20983235", "title": "The physiology of immobilization and the local effects of heat and cold.", "content": "The physiology of immobilization and the local effects of heat and cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983235"}
{"pmid": "20983236", "title": "Medical significance of ocular torticollis.", "content": "Medical significance of ocular torticollis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983236"}
{"pmid": "20983234", "title": "The problem of Ewing sarcoma of bone.", "content": "The problem of Ewing sarcoma of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983234"}
{"pmid": "20983237", "title": "Metastatic neoplasm of pelvic bones treated by stilbestrol.", "content": "Metastatic neoplasm of pelvic bones treated by stilbestrol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983237"}
{"pmid": "20983239", "title": "Salmonella osteomyelitis.", "content": "Salmonella osteomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983239"}
{"pmid": "20983238", "title": "Report on the use of penicillin in the treatment of staphylococcal infections with special reference to acute and chronic osteomyelitis and several collateral studies.", "content": "Report on the use of penicillin in the treatment of staphylococcal infections with special reference to acute and chronic osteomyelitis and several collateral studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983238"}
{"pmid": "20983240", "title": "Surgical house cleaning in osteoarthritis of the knee.", "content": "Surgical house cleaning in osteoarthritis of the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983240"}
{"pmid": "20983241", "title": "The orientation of the joints of the lower extremity.", "content": "The orientation of the joints of the lower extremity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983241"}
{"pmid": "20983242", "title": "Spontaneous rupture of the bladder complicating treatment of fracture of the lumbar spine.", "content": "Spontaneous rupture of the bladder complicating treatment of fracture of the lumbar spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983242"}
{"pmid": "20983243", "title": "The relation of the extensor digitorum communis tendon to the metacarpophalangeal joint.", "content": "The relation of the extensor digitorum communis tendon to the metacarpophalangeal joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983243"}
{"pmid": "20983244", "title": "Stenosing tendovaginitis of the flexor longus pollicis disability other than trigger thumb.", "content": "Stenosing tendovaginitis of the flexor longus pollicis disability other than trigger thumb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983244"}
{"pmid": "20983245", "title": "The glomus tumor.", "content": "The glomus tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983245"}
{"pmid": "20983249", "title": "The carcinogenicity of p-monomethylaminoazobenzene in various diets and the activity of this dye relative to p-dimethylaminoazobenzene.", "content": "The carcinogenicity of p-monomethylaminoazobenzene in various diets and the activity of this dye relative to p-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983249"}
{"pmid": "20983250", "title": "Calcium, copper, and zinc in the epidermal carcinogenesis of mouse and man.", "content": "Calcium, copper, and zinc in the epidermal carcinogenesis of mouse and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983250"}
{"pmid": "20983251", "title": "Carcinogens and the regeneration patterns after injury.", "content": "Carcinogens and the regeneration patterns after injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983251"}
{"pmid": "20983252", "title": "The etiology of fowl tumors.", "content": "The etiology of fowl tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983252"}
{"pmid": "20983254", "title": "Some practical considerations of the rheumatic fever problem.", "content": "Some practical considerations of the rheumatic fever problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983254"}
{"pmid": "20983258", "title": "The symballophone.", "content": "The symballophone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983258"}
{"pmid": "20983260", "title": "The volumetric determination of nitroguanidine.", "content": "The volumetric determination of nitroguanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983260"}
{"pmid": "20983259", "title": "Notes on the selective oxidation of vinegar.", "content": "Notes on the selective oxidation of vinegar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983259"}
{"pmid": "20983261", "title": "The determination of boron by the use of quinalizarin.", "content": "The determination of boron by the use of quinalizarin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983261"}
{"pmid": "20983262", "title": "The gravimetri determination of tin in alloys by the tannin method.", "content": "The gravimetri determination of tin in alloys by the tannin method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983262"}
{"pmid": "20983263", "title": "The determination of selenium in copper mattes.", "content": "The determination of selenium in copper mattes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983263"}
{"pmid": "20983265", "title": "Note on the presence of heat-labile sulphur in milk powder made from milk pre-heated at a high temperature (190-200 degrees F.).", "content": "Note on the presence of heat-labile sulphur in milk powder made from milk pre-heated at a high temperature (190-200 degrees F.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983265"}
{"pmid": "20983264", "title": "The rapid determination of sodium in 50 per cent potassium hydroxide liquor, 50 per cent potassium carbonate liquor and solid potassium carbonate.", "content": "The rapid determination of sodium in 50 per cent potassium hydroxide liquor, 50 per cent potassium carbonate liquor and solid potassium carbonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983264"}
{"pmid": "20983266", "title": "Note on technique for microbiological assay of vitamins by methods involving mould growth.", "content": "Note on technique for microbiological assay of vitamins by methods involving mould growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983266"}
{"pmid": "20983267", "title": "The use of cupferron for the estimation of large quantities of iron in faeces.", "content": "The use of cupferron for the estimation of large quantities of iron in faeces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983267"}
{"pmid": "20983269", "title": "A note on the determination of nitrogen in foodstuffs by the Kjeldahl method; digestion conditions.", "content": "A note on the determination of nitrogen in foodstuffs by the Kjeldahl method; digestion conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983269"}
{"pmid": "20983268", "title": "Detection of manganese with aurintricarboxylic acid.", "content": "Detection of manganese with aurintricarboxylic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983268"}
{"pmid": "20983270", "title": "A carbonate estimation apparatus.", "content": "A carbonate estimation apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983270"}
{"pmid": "20983271", "title": "The determination of lime in refractory dead-burned magnesia.", "content": "The determination of lime in refractory dead-burned magnesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983271"}
{"pmid": "20983272", "title": "The efficiency of desiccants.", "content": "The efficiency of desiccants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983272"}
{"pmid": "20983273", "title": "The continuous production of doubly distilled water.", "content": "The continuous production of doubly distilled water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983273"}
{"pmid": "20983274", "title": "A thermostatically-controlled low temperature bath.", "content": "A thermostatically-controlled low temperature bath.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983274"}
{"pmid": "20983275", "title": "The tryptophane activity of various compounds for L. arabinosus and their influence on the determination of tryptophane in natural materials.", "content": "The tryptophane activity of various compounds for L. arabinosus and their influence on the determination of tryptophane in natural materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983275"}
{"pmid": "20983276", "title": "Factors influencing the maintenance of blood concentrations of sulfonamides.", "content": "Factors influencing the maintenance of blood concentrations of sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983276"}
{"pmid": "20983277", "title": "A growth factor for Lactobacillus gayoni 8289.", "content": "A growth factor for Lactobacillus gayoni 8289.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983277"}
{"pmid": "20983278", "title": "The excretion of B-complex vitamins in the urine and feces of seven normal adults.", "content": "The excretion of B-complex vitamins in the urine and feces of seven normal adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983278"}
{"pmid": "20983279", "title": "Quantity and quality of amylase produced by various bacterial isolates.", "content": "Quantity and quality of amylase produced by various bacterial isolates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983279"}
{"pmid": "20983280", "title": "Essential amino acid content of casein and fresh and processed cow's milk as determined microbiologically on hydrolyzates.", "content": "Essential amino acid content of casein and fresh and processed cow's milk as determined microbiologically on hydrolyzates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983280"}
{"pmid": "20983282", "title": "Application of nutritional studies for development of practical culture media for Bacillus anthracis.", "content": "Application of nutritional studies for development of practical culture media for Bacillus anthracis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983282"}
{"pmid": "20983281", "title": "Studies on the nutritional requirements of Bacillus anthracis.", "content": "Studies on the nutritional requirements of Bacillus anthracis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983281"}
{"pmid": "20983283", "title": "On the respiration of dermatophytes.", "content": "On the respiration of dermatophytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983283"}
{"pmid": "20983284", "title": "A submicro method for the determination of iodine number of lipids.", "content": "A submicro method for the determination of iodine number of lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983284"}
{"pmid": "20983285", "title": "The folic acid content of meats and the retention of this vitamin during cooking.", "content": "The folic acid content of meats and the retention of this vitamin during cooking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983285"}
{"pmid": "20983286", "title": "Changes in polyene synthesis induced by mutation in a red yeast (Rhodotorula rubra).", "content": "Changes in polyene synthesis induced by mutation in a red yeast (Rhodotorula rubra).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983286"}
{"pmid": "20983288", "title": "The content and biological availability of carotene in raw and dehydrated carrots and other vegetables.", "content": "The content and biological availability of carotene in raw and dehydrated carrots and other vegetables.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983288"}
{"pmid": "20983287", "title": "The content and biological availability of carotene in dehydrated carrots stored at high temperatures.", "content": "The content and biological availability of carotene in dehydrated carrots stored at high temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983287"}
{"pmid": "20983289", "title": "Observations on the inheritance of latex quality in Cryptostegia.", "content": "Observations on the inheritance of latex quality in Cryptostegia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983289"}
{"pmid": "20983290", "title": "A triterpene ester isolated from Cryptostegia madagascariensis latex.", "content": "A triterpene ester isolated from Cryptostegia madagascariensis latex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983290"}
{"pmid": "20983291", "title": "The carbonyl constituents of eucalyptus oils; the constitution of phellandral; d-, 1-, and d1-Beta isopropyladipic acids.", "content": "The carbonyl constituents of eucalyptus oils; the constitution of phellandral; d-, 1-, and d1-Beta isopropyladipic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983291"}
{"pmid": "20983292", "title": "Attempts to find new antimalarials; derivatives of 3:4:2':3'-pyridoacridine and 1:2:2':3'-pyridoacridine.", "content": "Attempts to find new antimalarials; derivatives of 3:4:2':3'-pyridoacridine and 1:2:2':3'-pyridoacridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983292"}
{"pmid": "20983293", "title": "Attempts to find new antimalarials; derivatives of o-phenanthroline (7:8:3':2'-pyridoquinoline).", "content": "Attempts to find new antimalarials; derivatives of o-phenanthroline (7:8:3':2'-pyridoquinoline).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983293"}
{"pmid": "20983294", "title": "The synthesis of antimalarial compounds related to niquidine; model experiments on the synthesis of quinolyl carbinols.", "content": "The synthesis of antimalarial compounds related to niquidine; model experiments on the synthesis of quinolyl carbinols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983294"}
{"pmid": "20983295", "title": "Recent work on corrosion and oxidation.", "content": "Recent work on corrosion and oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983295"}
{"pmid": "20983296", "title": "Hydroxamic acids from aliphatic dicarboxylic acids.", "content": "Hydroxamic acids from aliphatic dicarboxylic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983296"}
{"pmid": "20983297", "title": "Substituted alpha-dialkylaminoalkyl-l-naphthalenemethanols; some Mannich ketones and derived propanolamines.", "content": "Substituted alpha-dialkylaminoalkyl-l-naphthalenemethanols; some Mannich ketones and derived propanolamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983297"}
{"pmid": "20983298", "title": "Substituted alpha-dialkylaminoalkyl-l-naphthalenemethanols; synthesis of some propanolamines by means of Grignard reagents.", "content": "Substituted alpha-dialkylaminoalkyl-l-naphthalenemethanols; synthesis of some propanolamines by means of Grignard reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983298"}
{"pmid": "20983299", "title": "Substituted alpha-dialkylaminoalkyl-l-naphthalenemethanols; 5-, 6-, and 7-chloro derivatives.", "content": "Substituted alpha-dialkylaminoalkyl-l-naphthalenemethanols; 5-, 6-, and 7-chloro derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983299"}
{"pmid": "20983300", "title": "The use of the fused eutectic of sodium amide and potassium amide in organic syntheses.", "content": "The use of the fused eutectic of sodium amide and potassium amide in organic syntheses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983300"}
{"pmid": "20983301", "title": "7-Acetoxy-9-acetyl-1,2,3,4-tetrahydrophenanthrene and dialkylamino carbinols derived from it.", "content": "7-Acetoxy-9-acetyl-1,2,3,4-tetrahydrophenanthrene and dialkylamino carbinols derived from it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983301"}
{"pmid": "20983302", "title": "3-(2-Dialkylamino-1-hydroxyethyl) retene derivatives.", "content": "3-(2-Dialkylamino-1-hydroxyethyl) retene derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983302"}
{"pmid": "20983303", "title": "Antitubercular studies; heterocyclic fatty acids.", "content": "Antitubercular studies; heterocyclic fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983303"}
{"pmid": "20983304", "title": "The preparation of 8-quinolinesulfonic acid.", "content": "The preparation of 8-quinolinesulfonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983304"}
{"pmid": "20983305", "title": "Some decamethylene and undecamethylene diamines.", "content": "Some decamethylene and undecamethylene diamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983305"}
{"pmid": "20983306", "title": "The preparation of some C-alkylmorpholines.", "content": "The preparation of some C-alkylmorpholines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983306"}
{"pmid": "20983307", "title": "Attempts to find new antimalarials; amino alcohols of the type -CHOHCH(CH3)NR2 derived from tetrahydrophenanthrene.", "content": "Attempts to find new antimalarials; amino alcohols of the type -CHOHCH(CH3)NR2 derived from tetrahydrophenanthrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983307"}
{"pmid": "20983308", "title": "Attempts to find new antimalarials; phenyl beta-D-glucothiosides, diphenyl disulfides, phenyl thiocyanates, and related compounds.", "content": "Attempts to find new antimalarials; phenyl beta-D-glucothiosides, diphenyl disulfides, phenyl thiocyanates, and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983308"}
{"pmid": "20983309", "title": "The application of radium and x-rays to diseases of the mouth.", "content": "The application of radium and x-rays to diseases of the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983309"}
{"pmid": "20983315", "title": "The art of anaesthesia.", "content": "The art of anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983315"}
{"pmid": "20983316", "title": "How civilian internees fared for dental treatment in Hong Kong during the Japanese occupation.", "content": "How civilian internees fared for dental treatment in Hong Kong during the Japanese occupation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983316"}
{"pmid": "20983317", "title": "THE Teviot Report.", "content": "THE Teviot Report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983317"}
{"pmid": "20983311", "title": "A new approach to Hanau's laws of articulation.", "content": "A new approach to Hanau's laws of articulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983311"}
{"pmid": "20983310", "title": "Periodontia, its purpose and scope.", "content": "Periodontia, its purpose and scope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983310"}
{"pmid": "20983321", "title": "Trismus due to myositis ossificans traumatica; report of a case.", "content": "Trismus due to myositis ossificans traumatica; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983321"}
{"pmid": "20983313", "title": "Impacted lower third molar causing neuralgia and absorption of lower second molar.", "content": "Impacted lower third molar causing neuralgia and absorption of lower second molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983313"}
{"pmid": "20983322", "title": "Removal of multiple impacted teeth; report of a case.", "content": "Removal of multiple impacted teeth; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983322"}
{"pmid": "20983312", "title": "Mixed salivary tumour of the palate.", "content": "Mixed salivary tumour of the palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983312"}
{"pmid": "20983323", "title": "Adamaninoma of the mandible; report of case.", "content": "Adamaninoma of the mandible; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983323"}
{"pmid": "20983324", "title": "Extensive cystic tumors of the mandible; report of case.", "content": "Extensive cystic tumors of the mandible; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983324"}
{"pmid": "20983325", "title": "Paget's disease involving the maxilla and the mandible; report of a case.", "content": "Paget's disease involving the maxilla and the mandible; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983325"}
{"pmid": "20983326", "title": "Conservative treatment of dental root cyst; report of case.", "content": "Conservative treatment of dental root cyst; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983326"}
{"pmid": "20983314", "title": "Whither dentistry?", "content": "Whither dentistry?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983314"}
{"pmid": "20983327", "title": "Removal of two mandibular super-numerary teeth to allow eruption of lower second bicuspid.", "content": "Removal of two mandibular super-numerary teeth to allow eruption of lower second bicuspid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983327"}
{"pmid": "20983328", "title": "Oral lesions of granuloma inguinale; report of three cases.", "content": "Oral lesions of granuloma inguinale; report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983328"}
{"pmid": "20983329", "title": "Submaxillary duct and gland stones; report of a case.", "content": "Submaxillary duct and gland stones; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983329"}
{"pmid": "20983330", "title": "A myxomatous tumor simulating a dentigerous cyst.", "content": "A myxomatous tumor simulating a dentigerous cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983330"}
{"pmid": "20983331", "title": "Ameloblastoma of the mandible; report of a case.", "content": "Ameloblastoma of the mandible; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983331"}
{"pmid": "20983332", "title": "Dentinoma; report of a case.", "content": "Dentinoma; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983332"}
{"pmid": "20983333", "title": "Use of petrolatum as dressing in third molar sockets; report of a case.", "content": "Use of petrolatum as dressing in third molar sockets; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983333"}
{"pmid": "20983334", "title": "Ranula (cystic tumor); report of case.", "content": "Ranula (cystic tumor); report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983334"}
{"pmid": "20983335", "title": "Muco-epidermoid tumors of the salivary glands; a report of three cases.", "content": "Muco-epidermoid tumors of the salivary glands; a report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983335"}
{"pmid": "20983336", "title": "Multiple lymphosarcoma (lymphoblastoma) of the oral and cervical regions.", "content": "Multiple lymphosarcoma (lymphoblastoma) of the oral and cervical regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983336"}
{"pmid": "20983338", "title": "Delayed union of mandibular fractures.", "content": "Delayed union of mandibular fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983338"}
{"pmid": "20983337", "title": "Torus; report of case.", "content": "Torus; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983337"}
{"pmid": "20983339", "title": "Periodontal cyst; report of case.", "content": "Periodontal cyst; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983339"}
{"pmid": "20983340", "title": "Transitional cell carcinoma (lymphoepithelioma) of the upper jaw; report of case.", "content": "Transitional cell carcinoma (lymphoepithelioma) of the upper jaw; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983340"}
{"pmid": "20983350", "title": "Psychogenic factors in oral disease.", "content": "Psychogenic factors in oral disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983350"}
{"pmid": "20983351", "title": "Fitting the patient to the denture.", "content": "Fitting the patient to the denture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983351"}
{"pmid": "20983342", "title": "A comparative study of the resorption of alveolar ridge tissue under immediate dentures.", "content": "A comparative study of the resorption of alveolar ridge tissue under immediate dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983342"}
{"pmid": "20983343", "title": "A report on two unusual partial dentures.", "content": "A report on two unusual partial dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983343"}
{"pmid": "20983341", "title": "A comparison of some modern methods for obtaining stability and retention for lower dentures.", "content": "A comparison of some modern methods for obtaining stability and retention for lower dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983341"}
{"pmid": "20983356", "title": "Dental disease as a fundamental problem.", "content": "Dental disease as a fundamental problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983356"}
{"pmid": "20983344", "title": "A comparison of various materials used in taking mandibular impressions in complete denture prosthesis.", "content": "A comparison of various materials used in taking mandibular impressions in complete denture prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983344"}
{"pmid": "20983357", "title": "Gingivitis and penicillin administration.", "content": "Gingivitis and penicillin administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983357"}
{"pmid": "20983382", "title": "Dermatitis of the hands due to atopic allergy to pollen.", "content": "Dermatitis of the hands due to atopic allergy to pollen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983382"}
{"pmid": "20983383", "title": "Treatment of tinea capitia with special iodine and dilute acetic acid.", "content": "Treatment of tinea capitia with special iodine and dilute acetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983383"}
{"pmid": "20983384", "title": "Treatment of tinea capitis with roentgen rays.", "content": "Treatment of tinea capitis with roentgen rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983384"}
{"pmid": "20983385", "title": "Juxta-articular node of leprous origin.", "content": "Juxta-articular node of leprous origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983385"}
{"pmid": "20983386", "title": "Acute idiopathic circumscribed cutaneous gangrene.", "content": "Acute idiopathic circumscribed cutaneous gangrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983386"}
{"pmid": "20983387", "title": "Isolation of dermatophytes.", "content": "Isolation of dermatophytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983387"}
{"pmid": "20983388", "title": "Electrosurgical removal of plantar warts (loop treatment).", "content": "Electrosurgical removal of plantar warts (loop treatment).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983388"}
{"pmid": "20983389", "title": "Tyrothricin in the treatment of diseases of the skin.", "content": "Tyrothricin in the treatment of diseases of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983389"}
{"pmid": "20983390", "title": "Nevus flammeus with glaucoma.", "content": "Nevus flammeus with glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983390"}
{"pmid": "20983391", "title": "Exfoliative dermatitis associated with amebic dysentery.", "content": "Exfoliative dermatitis associated with amebic dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983391"}
{"pmid": "20983392", "title": "Treatment of varicose ulcers with silver-coated adhesive tape.", "content": "Treatment of varicose ulcers with silver-coated adhesive tape.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983392"}
{"pmid": "20983393", "title": "A case for diagnosis (necrobiosis lipoidica?).", "content": "A case for diagnosis (necrobiosis lipoidica?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983393"}
{"pmid": "20983394", "title": "Necrobiosis lipoidica diabeticorum.", "content": "Necrobiosis lipoidica diabeticorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983394"}
{"pmid": "20983395", "title": "Tinea capitis.", "content": "Tinea capitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983395"}
{"pmid": "20983396", "title": "Epidermolysis bullosa with palmar and plantar keratosis and verrucous lesions at sites of previous lesions.", "content": "Epidermolysis bullosa with palmar and plantar keratosis and verrucous lesions at sites of previous lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983396"}
{"pmid": "20983397", "title": "A case for diagnosis (purpuric lichenoid dermatitis; Schamberg's disease?).", "content": "A case for diagnosis (purpuric lichenoid dermatitis; Schamberg's disease?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983397"}
{"pmid": "20983398", "title": "Miliary papular tuberculid.", "content": "Miliary papular tuberculid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983398"}
{"pmid": "20983399", "title": "Pityriasis rosea (tinea versicolor?) with leukoderma.", "content": "Pityriasis rosea (tinea versicolor?) with leukoderma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983399"}
{"pmid": "20983400", "title": "A case for diagnosis (von Recklinghausen's disease?).", "content": "A case for diagnosis (von Recklinghausen's disease?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983400"}
{"pmid": "20983401", "title": "Necrobiosis lipoidica.", "content": "Necrobiosis lipoidica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983401"}
{"pmid": "20983402", "title": "Granuloma annulare with lesions limited to the face and resembling basal cell epitheliomas.", "content": "Granuloma annulare with lesions limited to the face and resembling basal cell epitheliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983402"}
{"pmid": "20983403", "title": "Pityriasis rubra pilaris.", "content": "Pityriasis rubra pilaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983403"}
{"pmid": "20983404", "title": "Tuberculosis orificialis.", "content": "Tuberculosis orificialis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983404"}
{"pmid": "20983405", "title": "Keratosis of palms (treated).", "content": "Keratosis of palms (treated).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983405"}
{"pmid": "20983406", "title": "Pityriasis rosea resembling secondary syphilis.", "content": "Pityriasis rosea resembling secondary syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983406"}
{"pmid": "20983407", "title": "Blastomycosis.", "content": "Blastomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983407"}
{"pmid": "20983408", "title": "Generalized progressive scleroderma.", "content": "Generalized progressive scleroderma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983408"}
{"pmid": "20983409", "title": "A case for diagnosis (syphilitic verruciform melanoleukoderma?).", "content": "A case for diagnosis (syphilitic verruciform melanoleukoderma?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983409"}
{"pmid": "20983410", "title": "Syphilis with amyotrophic lateral sclerosis.", "content": "Syphilis with amyotrophic lateral sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983410"}
{"pmid": "20983411", "title": "Lentigo.", "content": "Lentigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983411"}
{"pmid": "20983412", "title": "A case for diagnosis (localized scleroderma?).", "content": "A case for diagnosis (localized scleroderma?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983412"}
{"pmid": "20983413", "title": "Charcot joint of the right ankle.", "content": "Charcot joint of the right ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983413"}
{"pmid": "20983414", "title": "Pityriasis rubra pilaris.", "content": "Pityriasis rubra pilaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983414"}
{"pmid": "20983415", "title": "Pigmentation following morphea (and arsenic?).", "content": "Pigmentation following morphea (and arsenic?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983415"}
{"pmid": "20983416", "title": "A case for diagnosis (lichen planus?).", "content": "A case for diagnosis (lichen planus?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983416"}
{"pmid": "20983417", "title": "Perifolliculitis capitis abscedens et suffodiens, cleared with penicillin.", "content": "Perifolliculitis capitis abscedens et suffodiens, cleared with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983417"}
{"pmid": "20983418", "title": "A case for diagnosis (psoriasis?).", "content": "A case for diagnosis (psoriasis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983418"}
{"pmid": "20983419", "title": "A case for diagnosis (mycosis fungoides).", "content": "A case for diagnosis (mycosis fungoides).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983419"}
{"pmid": "20983420", "title": "Acrosclerosis (Sellei).", "content": "Acrosclerosis (Sellei).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983420"}
{"pmid": "20983421", "title": "Scrofulous gummas.", "content": "Scrofulous gummas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983421"}
{"pmid": "20983422", "title": "A case for diagnosis (erythema multiforme bullosum?).", "content": "A case for diagnosis (erythema multiforme bullosum?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983422"}
{"pmid": "20983423", "title": "A case for diagnosis (lupus erythematosus; seborrheic dermatitis?).", "content": "A case for diagnosis (lupus erythematosus; seborrheic dermatitis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983423"}
{"pmid": "20983424", "title": "Purpura annularis telangiectodes.", "content": "Purpura annularis telangiectodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983424"}
{"pmid": "20983425", "title": "Dermatofibroma protuberans.", "content": "Dermatofibroma protuberans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983425"}
{"pmid": "20983426", "title": "A case for diagnosis (lichen scrofulosus; vitamin A deficiency?).", "content": "A case for diagnosis (lichen scrofulosus; vitamin A deficiency?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983426"}
{"pmid": "20983427", "title": "Urticaria pigmentosa.", "content": "Urticaria pigmentosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983427"}
{"pmid": "20983428", "title": "Erythema exudativum multiforme.", "content": "Erythema exudativum multiforme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983428"}
{"pmid": "20983429", "title": "A case for diagnosis. [Xanthoma].", "content": "A case for diagnosis. [Xanthoma].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983429"}
{"pmid": "20983430", "title": "A case for diagnosis (eosinophilic granuloma?).", "content": "A case for diagnosis (eosinophilic granuloma?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983430"}
{"pmid": "20983435", "title": "Technique of Rh testing.", "content": "Technique of Rh testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983435"}
{"pmid": "20983436", "title": "An experimental evaluation of the Mazzini Slide Test.", "content": "An experimental evaluation of the Mazzini Slide Test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983436"}
{"pmid": "20983437", "title": "Experiences of a medical technologist in the Canal Zone.", "content": "Experiences of a medical technologist in the Canal Zone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983437"}
{"pmid": "20983438", "title": "Pernicious anemia.", "content": "Pernicious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983438"}
{"pmid": "20983443", "title": "Observations on efficiency of swimmers as related to some changes in pre-exercise nutriment.", "content": "Observations on efficiency of swimmers as related to some changes in pre-exercise nutriment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983443"}
{"pmid": "20983442", "title": "Influence of diet on plasma fibrinogen in the chick.", "content": "Influence of diet on plasma fibrinogen in the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983442"}
{"pmid": "20983444", "title": "Biological value of proteins in relation to the essential amino acids which they contain; the endogenous nitrogen of man.", "content": "Biological value of proteins in relation to the essential amino acids which they contain; the endogenous nitrogen of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983444"}
{"pmid": "20983445", "title": "Biological value of proteins in relation to the essential amino acids which they contain; interconvertibility of biological values illustrated by supplementing egg and soy protein with essential amino acids.", "content": "Biological value of proteins in relation to the essential amino acids which they contain; interconvertibility of biological values illustrated by supplementing egg and soy protein with essential amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983445"}
{"pmid": "20983446", "title": "The influence of phosphorus, calcium and vitamin D3 upon the fat content of the skelton in growing pigs.", "content": "The influence of phosphorus, calcium and vitamin D3 upon the fat content of the skelton in growing pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983446"}
{"pmid": "20983447", "title": "The ascorbic acid content of whole blood plasma of normal rats with evidence of a sex difference.", "content": "The ascorbic acid content of whole blood plasma of normal rats with evidence of a sex difference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983447"}
{"pmid": "20983448", "title": "The relative efficiency of different forms of intravenously administered nitrogen on nitrogen balance and amino acid excretion.", "content": "The relative efficiency of different forms of intravenously administered nitrogen on nitrogen balance and amino acid excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983448"}
{"pmid": "20983449", "title": "The influence of sources of phosphorus on the relative efficiency of vitamin D3 and cod liver oil in promoting calcification in poults.", "content": "The influence of sources of phosphorus on the relative efficiency of vitamin D3 and cod liver oil in promoting calcification in poults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983449"}
{"pmid": "20983450", "title": "Some interrelationships of dietary iron, copper and cobalt in metabolism.", "content": "Some interrelationships of dietary iron, copper and cobalt in metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983450"}
{"pmid": "20983452", "title": "A comparison of four methods for studying the urinary excretion of thiamine.", "content": "A comparison of four methods for studying the urinary excretion of thiamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983452"}
{"pmid": "20983451", "title": "Factors affecting the occurrence of hemorrhagic kidneys due to choline deficiency.", "content": "Factors affecting the occurrence of hemorrhagic kidneys due to choline deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983451"}
{"pmid": "20983453", "title": "Nutrition in the public health programs.", "content": "Nutrition in the public health programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983453"}
{"pmid": "20983454", "title": "PRESENT knowledge of the vitamin B-complex in human nutrition.", "content": "PRESENT knowledge of the vitamin B-complex in human nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983454"}
{"pmid": "20983455", "title": "VITAMIN composition of human milk.", "content": "VITAMIN composition of human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983455"}
{"pmid": "20983456", "title": "CEROID pigment in dietary cirrhosis of rats.", "content": "CEROID pigment in dietary cirrhosis of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983456"}
{"pmid": "20983457", "title": "MALNUTRITION in edentulous patients.", "content": "MALNUTRITION in edentulous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983457"}
{"pmid": "20983459", "title": "CHRONIC fluorine intoxication and the skeletal system.", "content": "CHRONIC fluorine intoxication and the skeletal system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983459"}
{"pmid": "20983458", "title": "WARTIME dental caries incidence.", "content": "WARTIME dental caries incidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983458"}
{"pmid": "20983460", "title": "IMPROVEMENTS in ascorbic acid and thiamine determinations.", "content": "IMPROVEMENTS in ascorbic acid and thiamine determinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983460"}
{"pmid": "20983461", "title": "FATE of tryptophane in mammals.", "content": "FATE of tryptophane in mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983461"}
{"pmid": "20983462", "title": "SURVEY of hemoglobin levels in Great Britain in 1943.", "content": "SURVEY of hemoglobin levels in Great Britain in 1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983462"}
{"pmid": "20983463", "title": "VITAMIN D content of human milk.", "content": "VITAMIN D content of human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983463"}
{"pmid": "20983480", "title": "Insulin inhibition by serum of insulin resistant patient.", "content": "Insulin inhibition by serum of insulin resistant patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983480"}
{"pmid": "20983481", "title": "Hormone metabolites in blood and urine of diabetic pregnant patients with and without toxemia.", "content": "Hormone metabolites in blood and urine of diabetic pregnant patients with and without toxemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983481"}
{"pmid": "20983482", "title": "Recurrent diabetes; spontaneous remissions and exacerbations.", "content": "Recurrent diabetes; spontaneous remissions and exacerbations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983482"}
{"pmid": "20983483", "title": "The influence of various and rogenic steroids on nitrogen balance and growth.", "content": "The influence of various and rogenic steroids on nitrogen balance and growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983483"}
{"pmid": "20983475", "title": "Diverticulosis and diverticulitis of the colon.", "content": "Diverticulosis and diverticulitis of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983475"}
{"pmid": "20983476", "title": "Influence of some vitamins and hormones in the prevention of experimental cinchophen peptic ulcer.", "content": "Influence of some vitamins and hormones in the prevention of experimental cinchophen peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983476"}
{"pmid": "20983477", "title": "Dietotherapy in gastrointestinal diseases.", "content": "Dietotherapy in gastrointestinal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983477"}
{"pmid": "20983484", "title": "Progesterone therapy in uterine fibromyoma.", "content": "Progesterone therapy in uterine fibromyoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983484"}
{"pmid": "20983479", "title": "Relationship between uremia and peptic ulcer.", "content": "Relationship between uremia and peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983479"}
{"pmid": "20983478", "title": "The enema; some historical notes.", "content": "The enema; some historical notes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983478"}
{"pmid": "20983487", "title": "Marshalling of proofs in homicide cases.", "content": "Marshalling of proofs in homicide cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983487"}
{"pmid": "20983486", "title": "Forensic immunology.", "content": "Forensic immunology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983486"}
{"pmid": "20983488", "title": "The postmortem examination in cases of suspected homicide.", "content": "The postmortem examination in cases of suspected homicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983488"}
{"pmid": "20983500", "title": "The mother or the child.", "content": "The mother or the child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983500"}
{"pmid": "20983501", "title": "HISTORIC event in Scotland.", "content": "HISTORIC event in Scotland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983501"}
{"pmid": "20983502", "title": "The health centre and the community.", "content": "The health centre and the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983502"}
{"pmid": "20983503", "title": "The Birmingham Institute of Child Health.", "content": "The Birmingham Institute of Child Health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983503"}
{"pmid": "20983485", "title": "The law of homicide.", "content": "The law of homicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983485"}
{"pmid": "20983512", "title": "Professional services in the postwar hospital.", "content": "Professional services in the postwar hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983512"}
{"pmid": "20983513", "title": "Lessons in disaster.", "content": "Lessons in disaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983513"}
{"pmid": "20983514", "title": "Six essentials to effective hospital care.", "content": "Six essentials to effective hospital care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983514"}
{"pmid": "20983515", "title": "The world's oldest cancer hospital.", "content": "The world's oldest cancer hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983515"}
{"pmid": "20983516", "title": "The widening horizon in cancer education and treatment.", "content": "The widening horizon in cancer education and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983516"}
{"pmid": "20983517", "title": "The war's effect on the Catholic hospital.", "content": "The war's effect on the Catholic hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983517"}
{"pmid": "20983518", "title": "CATHOLIC hospitals in Milwaukee and vicinity.", "content": "CATHOLIC hospitals in Milwaukee and vicinity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983518"}
{"pmid": "20983519", "title": "CATHOLIC hospitals of Wisconsin.", "content": "CATHOLIC hospitals of Wisconsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983519"}
{"pmid": "20983520", "title": "The hospitalization of veterans in private hospitals.", "content": "The hospitalization of veterans in private hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983520"}
{"pmid": "20983521", "title": "Waver of confidential status.", "content": "Waver of confidential status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983521"}
{"pmid": "20983522", "title": "The health of forestry workers; a survey of the Women's Timber Corps of Great Britain.", "content": "The health of forestry workers; a survey of the Women's Timber Corps of Great Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983522"}
{"pmid": "20983523", "title": "Medical grading of the industrial worker.", "content": "Medical grading of the industrial worker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983523"}
{"pmid": "20983524", "title": "Measurements of radioactivity in an industrial dial painting room.", "content": "Measurements of radioactivity in an industrial dial painting room.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983524"}
{"pmid": "20983525", "title": "Clinical effects of tetryl (CE powder).", "content": "Clinical effects of tetryl (CE powder).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983525"}
{"pmid": "20983526", "title": "Monocytosis as an index of TNT absorption.", "content": "Monocytosis as an index of TNT absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983526"}
{"pmid": "20983527", "title": "MEDICAL science and physical education in industry.", "content": "MEDICAL science and physical education in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983527"}
{"pmid": "20983528", "title": "Health, physical education and recreation for India.", "content": "Health, physical education and recreation for India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983528"}
{"pmid": "20983529", "title": "Industrial absenteeism.", "content": "Industrial absenteeism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983529"}
{"pmid": "20983530", "title": "Medical social work in rural areas.", "content": "Medical social work in rural areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983530"}
{"pmid": "20983531", "title": "Crime; some social aspects.", "content": "Crime; some social aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983531"}
{"pmid": "20983532", "title": "Rescue homes for women in Bombay.", "content": "Rescue homes for women in Bombay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983532"}
{"pmid": "20983536", "title": "Atresia anal.", "content": "Atresia anal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983536"}
{"pmid": "20983538", "title": "A clinical analysis of primary atypical pneumonia with a discussion of electrocardiographic findings.", "content": "A clinical analysis of primary atypical pneumonia with a discussion of electrocardiographic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983538"}
{"pmid": "20983540", "title": "Rheumatic heart disease in New Guinea; including a cardiovascular survey of 200 native Papuans.", "content": "Rheumatic heart disease in New Guinea; including a cardiovascular survey of 200 native Papuans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983540"}
{"pmid": "20983539", "title": "The management of chronic arthritis and other rheumatic diseases among soldiers of the United States Army.", "content": "The management of chronic arthritis and other rheumatic diseases among soldiers of the United States Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983539"}
{"pmid": "20983541", "title": "The doctor as a witness.", "content": "The doctor as a witness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983541"}
{"pmid": "20983542", "title": "Observations on mass chemo-prophylaxis with sulfadiazine.", "content": "Observations on mass chemo-prophylaxis with sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983542"}
{"pmid": "20983543", "title": "Peptic ulcer in identical twins.", "content": "Peptic ulcer in identical twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983543"}
{"pmid": "20983544", "title": "Diphtheria carriers treated with penicillin.", "content": "Diphtheria carriers treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983544"}
{"pmid": "20983545", "title": "Hypoglycemia in neuropsychiatry.", "content": "Hypoglycemia in neuropsychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983545"}
{"pmid": "20983546", "title": "Blood plasma proteins in patients with heart failure.", "content": "Blood plasma proteins in patients with heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983546"}
{"pmid": "20983547", "title": "Massive doses of penicillin in the treatment of subacute bacterial endocarditis.", "content": "Massive doses of penicillin in the treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983547"}
{"pmid": "20983548", "title": "A case of lymphogranuloma venereum associated with atypical pneumonia.", "content": "A case of lymphogranuloma venereum associated with atypical pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983548"}
{"pmid": "20983549", "title": "A case of coronary thrombosis with myocardial infarction in a 19 year old white male.", "content": "A case of coronary thrombosis with myocardial infarction in a 19 year old white male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983549"}
{"pmid": "20983551", "title": "A case of short PR interval and prolonged QRS complex with a paroxysm of ventricular tachycardia.", "content": "A case of short PR interval and prolonged QRS complex with a paroxysm of ventricular tachycardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983551"}
{"pmid": "20983550", "title": "Paroxysmal ventricular tachycardia associated with short P-R intervals and prolonged QRS complexes.", "content": "Paroxysmal ventricular tachycardia associated with short P-R intervals and prolonged QRS complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983550"}
{"pmid": "20983552", "title": "IMMUNIZATION with pneumococcus polysaccharide.", "content": "IMMUNIZATION with pneumococcus polysaccharide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983552"}
{"pmid": "20983573", "title": "Some results of transfusion of blood to recipients with cold agglutinins.", "content": "Some results of transfusion of blood to recipients with cold agglutinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983573"}
{"pmid": "20983574", "title": "Migrainous, ciliary, and post-traumatic dural headaches.", "content": "Migrainous, ciliary, and post-traumatic dural headaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983574"}
{"pmid": "20983575", "title": "The catheter and the prostate.", "content": "The catheter and the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983575"}
{"pmid": "20983576", "title": "Fatigue syndromes in West Africa.", "content": "Fatigue syndromes in West Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983576"}
{"pmid": "20983577", "title": "Identical deformities in the nasal septum of a pair of identical twins.", "content": "Identical deformities in the nasal septum of a pair of identical twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983577"}
{"pmid": "20983579", "title": "Varicella herpetiformis.", "content": "Varicella herpetiformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983579"}
{"pmid": "20983578", "title": "Examination of the lower uterine segment in cases of suspected placenta praevia.", "content": "Examination of the lower uterine segment in cases of suspected placenta praevia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983578"}
{"pmid": "20983580", "title": "Injury to the tonsil.", "content": "Injury to the tonsil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983580"}
{"pmid": "20983582", "title": "The intractable vesico-vaginal fistula.", "content": "The intractable vesico-vaginal fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983582"}
{"pmid": "20983581", "title": "What the Russians eat.", "content": "What the Russians eat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983581"}
{"pmid": "20983584", "title": "REPORT of the Interdepartmental Committee on Remuneration of General Practitioners.", "content": "REPORT of the Interdepartmental Committee on Remuneration of General Practitioners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983584"}
{"pmid": "20983583", "title": "Medical supplies on merchant ships.", "content": "Medical supplies on merchant ships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983583"}
{"pmid": "20983585", "title": "Progress after perforated peptic ulcer.", "content": "Progress after perforated peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983585"}
{"pmid": "20983586", "title": "One hundred cases of perforated peptic ulcer; with an analysis of immediate and remote results of simple closure.", "content": "One hundred cases of perforated peptic ulcer; with an analysis of immediate and remote results of simple closure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983586"}
{"pmid": "20983587", "title": "The prognosis of immaturity.", "content": "The prognosis of immaturity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983587"}
{"pmid": "20983588", "title": "Treatment of mustard gas burns.", "content": "Treatment of mustard gas burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983588"}
{"pmid": "20983589", "title": "Volvulus of the small intestine.", "content": "Volvulus of the small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983589"}
{"pmid": "20983590", "title": "Leukaemic infiltration of the site of herpes zoster.", "content": "Leukaemic infiltration of the site of herpes zoster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983590"}
{"pmid": "20983591", "title": "PLACEMENT of the disabled.", "content": "PLACEMENT of the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983591"}
{"pmid": "20983592", "title": "Suprapubic drainage of bladder.", "content": "Suprapubic drainage of bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983592"}
{"pmid": "20983593", "title": "The fallacy of the IQ.", "content": "The fallacy of the IQ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983593"}
{"pmid": "20983594", "title": "Frontal lobotomy.", "content": "Frontal lobotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983594"}
{"pmid": "20983595", "title": "Postural reflexes.", "content": "Postural reflexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983595"}
{"pmid": "20983596", "title": "Pregnancy does not produce dental caries.", "content": "Pregnancy does not produce dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983596"}
{"pmid": "20983597", "title": "Penicillin; pharmacology and methods of administration.", "content": "Penicillin; pharmacology and methods of administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983597"}
{"pmid": "20983598", "title": "Fluctuations of anatomical teaching.", "content": "Fluctuations of anatomical teaching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983598"}
{"pmid": "20983599", "title": "Obstetrics and gynecology in the United States Army.", "content": "Obstetrics and gynecology in the United States Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983599"}
{"pmid": "20983600", "title": "Penicillin therapy in pediatrics.", "content": "Penicillin therapy in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983600"}
{"pmid": "20983608", "title": "Aerosol therapy of the lungs and bronchi with special reference to penicillin and hydrogen peroxide.", "content": "Aerosol therapy of the lungs and bronchi with special reference to penicillin and hydrogen peroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983608"}
{"pmid": "20983609", "title": "The handling of the intracranial tumor suspect.", "content": "The handling of the intracranial tumor suspect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983609"}
{"pmid": "20983610", "title": "Venous catheterization for the diagnosis of congenital heart disease.", "content": "Venous catheterization for the diagnosis of congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983610"}
{"pmid": "20983611", "title": "Recent advances in the treatment of Laennec's cirrhosis.", "content": "Recent advances in the treatment of Laennec's cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983611"}
{"pmid": "20983612", "title": "Cancer of the uterus; diagnosis and management.", "content": "Cancer of the uterus; diagnosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983612"}
{"pmid": "20983613", "title": "The etiology of pruritis ani.", "content": "The etiology of pruritis ani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983613"}
{"pmid": "20983614", "title": "Propylthiouracil for hyperthyroidism.", "content": "Propylthiouracil for hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983614"}
{"pmid": "20983615", "title": "Antibiotics.", "content": "Antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983615"}
{"pmid": "20983616", "title": "Antibiotics used locally in sinus infections.", "content": "Antibiotics used locally in sinus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983616"}
{"pmid": "20983617", "title": "The treatment of acute and chronic pulmonary disease with penicillin aerosol.", "content": "The treatment of acute and chronic pulmonary disease with penicillin aerosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983617"}
{"pmid": "20983618", "title": "Oral folic acid therapy in the treatment of pernicious (Addisonian) anaemia.", "content": "Oral folic acid therapy in the treatment of pernicious (Addisonian) anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983618"}
{"pmid": "20983619", "title": "Observations on German war surgery.", "content": "Observations on German war surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983619"}
{"pmid": "20983620", "title": "A familial peripheral neuropathy of unknown etiology resembling Morvan's disease.", "content": "A familial peripheral neuropathy of unknown etiology resembling Morvan's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983620"}
{"pmid": "20983621", "title": "Trans-pyloric prolapse of redundant gastric mucosal folds.", "content": "Trans-pyloric prolapse of redundant gastric mucosal folds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983621"}
{"pmid": "20983622", "title": "Postoperative early rising.", "content": "Postoperative early rising.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983622"}
{"pmid": "20983623", "title": "The use of aldarsone in the treatment of neurosyphilis.", "content": "The use of aldarsone in the treatment of neurosyphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983623"}
{"pmid": "20983624", "title": "Policy of Treatment Services, Department of Veterans' Affairs.", "content": "Policy of Treatment Services, Department of Veterans' Affairs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983624"}
{"pmid": "20983625", "title": "Modern conceptions of the pathogenesis and morbid anatomy of malaria.", "content": "Modern conceptions of the pathogenesis and morbid anatomy of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983625"}
{"pmid": "20983626", "title": "A statistical analysis of 1,214 cases of carcinoma.", "content": "A statistical analysis of 1,214 cases of carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983626"}
{"pmid": "20983627", "title": "Combined anaesthesia, using pentothal, cyclopropane, nitrous oxide, oxygen.", "content": "Combined anaesthesia, using pentothal, cyclopropane, nitrous oxide, oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983627"}
{"pmid": "20983628", "title": "Migraine: its treatment with prostigmine bromide.", "content": "Migraine: its treatment with prostigmine bromide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983628"}
{"pmid": "20983629", "title": "The role of riboflavin in migraine.", "content": "The role of riboflavin in migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983629"}
{"pmid": "20983630", "title": "Arterio-venous fistula.", "content": "Arterio-venous fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983630"}
{"pmid": "20983631", "title": "Hereditary ectodermal defect.", "content": "Hereditary ectodermal defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983631"}
{"pmid": "20983633", "title": "Reconstruction of the common bile duct with a monel metal tube.", "content": "Reconstruction of the common bile duct with a monel metal tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983633"}
{"pmid": "20983632", "title": "Discoid cartilage of the knee.", "content": "Discoid cartilage of the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983632"}
{"pmid": "20983634", "title": "Bronchial stenosis and atelectasis from sulphur dioxide.", "content": "Bronchial stenosis and atelectasis from sulphur dioxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983634"}
{"pmid": "20983635", "title": "The widening horizon in cancer education and treatment in Ontario.", "content": "The widening horizon in cancer education and treatment in Ontario.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983635"}
{"pmid": "20983636", "title": "An instrument for continuous penicillin therapy.", "content": "An instrument for continuous penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983636"}
{"pmid": "20983637", "title": "FUNCTIONS OF Federal and provincial venereal disease control divisions.", "content": "FUNCTIONS OF Federal and provincial venereal disease control divisions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983637"}
{"pmid": "20983638", "title": "The development of Associated Medical Services Inc.", "content": "The development of Associated Medical Services Inc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983638"}
{"pmid": "20983639", "title": "Medical education in the 14th century.", "content": "Medical education in the 14th century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983639"}
{"pmid": "20983640", "title": "Clinical experiences of the medical consultant of the Fifth Service Command.", "content": "Clinical experiences of the medical consultant of the Fifth Service Command.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983640"}
{"pmid": "20983641", "title": "A review of the literature on primary atypical pneumonia.", "content": "A review of the literature on primary atypical pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983641"}
{"pmid": "20983642", "title": "Chronic agranulocytosis (idiopathic) with peripheral pancytopenia.", "content": "Chronic agranulocytosis (idiopathic) with peripheral pancytopenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983642"}
{"pmid": "20983646", "title": "The patient in the patient-physician relationship.", "content": "The patient in the patient-physician relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983646"}
{"pmid": "20983647", "title": "Psychiatry with psychosomatic implications in general hospital.", "content": "Psychiatry with psychosomatic implications in general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983647"}
{"pmid": "20983648", "title": "Psychoneurosis in the veteran.", "content": "Psychoneurosis in the veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983648"}
{"pmid": "20983649", "title": "Prepayment medical care.", "content": "Prepayment medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983649"}
{"pmid": "20983666", "title": "Eritroblastosis fetalis.", "content": "Eritroblastosis fetalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983666"}
{"pmid": "20983686", "title": "Some tropical diseases in general practice; a post-war legacy.", "content": "Some tropical diseases in general practice; a post-war legacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983686"}
{"pmid": "20983687", "title": "The diagnosis and control of gonorrhoea by bacteriological cultures; with a preliminary report on a new method for transporting clinical material.", "content": "The diagnosis and control of gonorrhoea by bacteriological cultures; with a preliminary report on a new method for transporting clinical material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983687"}
{"pmid": "20983688", "title": "A case of cerebro-spinal meningitis treated with penicillin after failing to respond to sulphonamide therapy.", "content": "A case of cerebro-spinal meningitis treated with penicillin after failing to respond to sulphonamide therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983688"}
{"pmid": "20983689", "title": "Plastic and dental prosthetic repair of jaw injuries.", "content": "Plastic and dental prosthetic repair of jaw injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983689"}
{"pmid": "20983690", "title": "The use of preserved blood plasma in civilian practice.", "content": "The use of preserved blood plasma in civilian practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983690"}
{"pmid": "20983691", "title": "Intra-mural group psychotherapy.", "content": "Intra-mural group psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983691"}
{"pmid": "20983692", "title": "Ochronosis-like pigmentation associated with the use of atabrine.", "content": "Ochronosis-like pigmentation associated with the use of atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983692"}
{"pmid": "20983693", "title": "Examination of the breasts and pelvic organs in apparently well women.", "content": "Examination of the breasts and pelvic organs in apparently well women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983693"}
{"pmid": "20983694", "title": "Psychiatry in industry.", "content": "Psychiatry in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983694"}
{"pmid": "20983695", "title": "Gout; still a forgotten disease.", "content": "Gout; still a forgotten disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983695"}
{"pmid": "20983696", "title": "Diagnostic value of exfoliated cells from cancerous tissues.", "content": "Diagnostic value of exfoliated cells from cancerous tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983696"}
{"pmid": "20983697", "title": "Prediction of fate of threatened abortion by pregnandiol.", "content": "Prediction of fate of threatened abortion by pregnandiol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983697"}
{"pmid": "20983698", "title": "Mumps involvement of the central nervous system.", "content": "Mumps involvement of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983698"}
{"pmid": "20983700", "title": "Health resort therapy in gastrointestinal disorders.", "content": "Health resort therapy in gastrointestinal disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983700"}
{"pmid": "20983699", "title": "Coronary thrombosis.", "content": "Coronary thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983699"}
{"pmid": "20983701", "title": "Acute bacterial endarteritis.", "content": "Acute bacterial endarteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983701"}
{"pmid": "20983703", "title": "ENRICHED 80 per cent extraction flour.", "content": "ENRICHED 80 per cent extraction flour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983703"}
{"pmid": "20983704", "title": "Sympathectomy in the treatment of peripheral vascular sclerosis.", "content": "Sympathectomy in the treatment of peripheral vascular sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983704"}
{"pmid": "20983705", "title": "The crush syndrome in obstetrics and gynecology.", "content": "The crush syndrome in obstetrics and gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983705"}
{"pmid": "20983702", "title": "The production of aerosols from medicated solutions; a combined steam generator and aerosolizer.", "content": "The production of aerosols from medicated solutions; a combined steam generator and aerosolizer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983702"}
{"pmid": "20983706", "title": "A clinical syndrome following exposure to atomic bomb explosions.", "content": "A clinical syndrome following exposure to atomic bomb explosions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983706"}
{"pmid": "20983707", "title": "Typhoid and paratyphoid A in immunized military personnel.", "content": "Typhoid and paratyphoid A in immunized military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983707"}
{"pmid": "20983708", "title": "The status of the general practitioner, present and future.", "content": "The status of the general practitioner, present and future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983708"}
{"pmid": "20983709", "title": "Accidental ingestion of DDT, with a note on its metabolism in man.", "content": "Accidental ingestion of DDT, with a note on its metabolism in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983709"}
{"pmid": "20983710", "title": "Aluminum hydroxide gel for erosions in patients with bowel fistulas.", "content": "Aluminum hydroxide gel for erosions in patients with bowel fistulas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983710"}
{"pmid": "20983711", "title": "Reconstruction of a bile duct with a vitallium tube and some suggestions for avoiding the need of such an object.", "content": "Reconstruction of a bile duct with a vitallium tube and some suggestions for avoiding the need of such an object.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983711"}
{"pmid": "20983712", "title": "Thrombo-angitis obliterans.", "content": "Thrombo-angitis obliterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983712"}
{"pmid": "20983713", "title": "Period of infectivity of patients with homologous serum jaundice and routes of infection in this disease.", "content": "Period of infectivity of patients with homologous serum jaundice and routes of infection in this disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983713"}
{"pmid": "20983715", "title": "Hemoglobin and plasma protein production; various proteins, concentrates, and digests influence blood protein production in anemia and hypoproteinemia.", "content": "Hemoglobin and plasma protein production; various proteins, concentrates, and digests influence blood protein production in anemia and hypoproteinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983715"}
{"pmid": "20983716", "title": "Immunochemical studies on blood groups; properties of the blood group A substance from pools of hog stomachs and of specific precipitates composed of A substance and homologous human antibody.", "content": "Immunochemical studies on blood groups; properties of the blood group A substance from pools of hog stomachs and of specific precipitates composed of A substance and homologous human antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983716"}
{"pmid": "20983717", "title": "Immunochemical studies on blood groups; properties of purified blood group A substances from individual hog stomach linings.", "content": "Immunochemical studies on blood groups; properties of purified blood group A substances from individual hog stomach linings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983717"}
{"pmid": "20983718", "title": "The preparation of sections of guinea pig liver for electron microscopy.", "content": "The preparation of sections of guinea pig liver for electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983718"}
{"pmid": "20983719", "title": "Sulfonamide chemotherapy of combined infection with influenza virus and bacteria.", "content": "Sulfonamide chemotherapy of combined infection with influenza virus and bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983719"}
{"pmid": "20983720", "title": "The challenge of postwar pediatrics.", "content": "The challenge of postwar pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983720"}
{"pmid": "20983721", "title": "The celiac syndrome.", "content": "The celiac syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983721"}
{"pmid": "20983722", "title": "The successful treatment of subacute bacterial endocarditis of children with penicillin.", "content": "The successful treatment of subacute bacterial endocarditis of children with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983722"}
{"pmid": "20983723", "title": "The use of general anesthesia in the treatment of extensive caries in problem children.", "content": "The use of general anesthesia in the treatment of extensive caries in problem children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983723"}
{"pmid": "20983725", "title": "Mesenteric cyst; report of a case.", "content": "Mesenteric cyst; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983725"}
{"pmid": "20983724", "title": "Mesenteric cysts causing intestinal obstruction in infancy; report of two cases.", "content": "Mesenteric cysts causing intestinal obstruction in infancy; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983724"}
{"pmid": "20983726", "title": "Treatment of chronic influenzal meningitis; heparin as an adjuvant.", "content": "Treatment of chronic influenzal meningitis; heparin as an adjuvant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983726"}
{"pmid": "20983727", "title": "Direct psychiatric treatment of the child.", "content": "Direct psychiatric treatment of the child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983727"}
{"pmid": "20983728", "title": "Giant-cell tumor of bone in a four-month-old infant.", "content": "Giant-cell tumor of bone in a four-month-old infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983728"}
{"pmid": "20983729", "title": "Two cases of hemolytic anemia with leukemoid reaction of the myeloid type.", "content": "Two cases of hemolytic anemia with leukemoid reaction of the myeloid type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983729"}
{"pmid": "20983747", "title": "Present policies in the treatment of the severely burned patient; an outline of treatment including the use of whole blood transfusions.", "content": "Present policies in the treatment of the severely burned patient; an outline of treatment including the use of whole blood transfusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983747"}
{"pmid": "20983748", "title": "Polycythemia vera; variability of presenting symptoms; economical and symptomatically satisfactory treatment with phenylhydrazine.", "content": "Polycythemia vera; variability of presenting symptoms; economical and symptomatically satisfactory treatment with phenylhydrazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983748"}
{"pmid": "20983749", "title": "Carbohydrate metabolism in osteoporosis and Paget's disease.", "content": "Carbohydrate metabolism in osteoporosis and Paget's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983749"}
{"pmid": "20983750", "title": "Misunderstood postnasal discharge.", "content": "Misunderstood postnasal discharge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983750"}
{"pmid": "20983751", "title": "A new interpretation of some so-called positive patch tests, with special reference to metals used in industry.", "content": "A new interpretation of some so-called positive patch tests, with special reference to metals used in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983751"}
{"pmid": "20983752", "title": "Thiouracil; a warning.", "content": "Thiouracil; a warning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983752"}
{"pmid": "20983753", "title": "The lipo-protein micelle theory of drug action.", "content": "The lipo-protein micelle theory of drug action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983753"}
{"pmid": "20983754", "title": "The foetal circulation and the changes which that circulation undergoes during and shortly after birth.", "content": "The foetal circulation and the changes which that circulation undergoes during and shortly after birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983754"}
{"pmid": "20983755", "title": "Certain physiological aspects of convalescence.", "content": "Certain physiological aspects of convalescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983755"}
{"pmid": "20983756", "title": "The health of India.", "content": "The health of India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983756"}
{"pmid": "20983757", "title": "English medicine from Harvey to Bright.", "content": "English medicine from Harvey to Bright.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983757"}
{"pmid": "20983783", "title": "Recent advances in the treatment of rheumatic fever; with special reference to sulfonamide prophylaxis and intravenous salicylate therapy.", "content": "Recent advances in the treatment of rheumatic fever; with special reference to sulfonamide prophylaxis and intravenous salicylate therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983783"}
{"pmid": "20983784", "title": "The heart in rheumatic fever.", "content": "The heart in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983784"}
{"pmid": "20983785", "title": "Susceptibility of the host in rheumatic fever.", "content": "Susceptibility of the host in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983785"}
{"pmid": "20983786", "title": "The incidence of abnormal oronasal lymphoid tissue in rheumatic fever patients.", "content": "The incidence of abnormal oronasal lymphoid tissue in rheumatic fever patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983786"}
{"pmid": "20983787", "title": "The problem of dosage in the administration of gold salts for rheumatoid arthritis.", "content": "The problem of dosage in the administration of gold salts for rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983787"}
{"pmid": "20983788", "title": "Toxic hepatitis during gold salts therapy; its effect on the course of the rheumatoid arthritis.", "content": "Toxic hepatitis during gold salts therapy; its effect on the course of the rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983788"}
{"pmid": "20983789", "title": "Pericardial effusion in rheumatoid arthritis.", "content": "Pericardial effusion in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983789"}
{"pmid": "20983790", "title": "Juvenile rheumatoid arthritis (Still's disease).", "content": "Juvenile rheumatoid arthritis (Still's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983790"}
{"pmid": "20983791", "title": "Menopausal arthritis.", "content": "Menopausal arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983791"}
{"pmid": "20983792", "title": "Pneumococcic arthritis treated with penicillin; report of six cases.", "content": "Pneumococcic arthritis treated with penicillin; report of six cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983792"}
{"pmid": "20983793", "title": "The recognition and management of gout.", "content": "The recognition and management of gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983793"}
{"pmid": "20983794", "title": "Roentgen therapy for rheumatic diseases.", "content": "Roentgen therapy for rheumatic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983794"}
{"pmid": "20983795", "title": "The use of vitamins in the treatment of chronic arthritis.", "content": "The use of vitamins in the treatment of chronic arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983795"}
{"pmid": "20983797", "title": "What can orthopedics offer the arthritic?", "content": "What can orthopedics offer the arthritic?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983797"}
{"pmid": "20983796", "title": "Physical therapy in chronic arthritis.", "content": "Physical therapy in chronic arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983796"}
{"pmid": "20983798", "title": "Cholesterol content of urine in arthritis.", "content": "Cholesterol content of urine in arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983798"}
{"pmid": "20983799", "title": "The treatment of syphilis with penicillin.", "content": "The treatment of syphilis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983799"}
{"pmid": "20983800", "title": "Hypertension due to arteriosclerosis, and its complications.", "content": "Hypertension due to arteriosclerosis, and its complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983800"}
{"pmid": "20983801", "title": "Obese thyropituitary deficiency in the female.", "content": "Obese thyropituitary deficiency in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983801"}
{"pmid": "20983802", "title": "An epidemic caused by a sulfadiazine-resistant strain of Group A Type 17 streptococcus.", "content": "An epidemic caused by a sulfadiazine-resistant strain of Group A Type 17 streptococcus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983802"}
{"pmid": "20983803", "title": "The diagnosis and treatment of Reiter's syndrome.", "content": "The diagnosis and treatment of Reiter's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983803"}
{"pmid": "20983804", "title": "Thio drugs in thyreotoxicosis.", "content": "Thio drugs in thyreotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983804"}
{"pmid": "20983805", "title": "Hospital blankets as a source of infection.", "content": "Hospital blankets as a source of infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983805"}
{"pmid": "20983807", "title": "Some notes on West's operation (endonasal dacryocystostomy).", "content": "Some notes on West's operation (endonasal dacryocystostomy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983807"}
{"pmid": "20983806", "title": "Spontaneous rupture of the spleen, with notes on two cases.", "content": "Spontaneous rupture of the spleen, with notes on two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983806"}
{"pmid": "20983808", "title": "New conceptions of malaria control.", "content": "New conceptions of malaria control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983808"}
{"pmid": "20983809", "title": "A case of tick typhus in North Queensland.", "content": "A case of tick typhus in North Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983809"}
{"pmid": "20983810", "title": "Staphylococcal meningitis and ventriculitis; cure by penicillin.", "content": "Staphylococcal meningitis and ventriculitis; cure by penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983810"}
{"pmid": "20983811", "title": "A case of diabetes mellitus with hyperlipaemia and hypercholesterolaemia.", "content": "A case of diabetes mellitus with hyperlipaemia and hypercholesterolaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983811"}
{"pmid": "20983812", "title": "A case of Ludwig's angina.", "content": "A case of Ludwig's angina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983812"}
{"pmid": "20983813", "title": "Points in statistics and aetiology. [Posterior presentation].", "content": "Points in statistics and aetiology. [Posterior presentation].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983813"}
{"pmid": "20983814", "title": "Some points in the aetiology and mechanism of occipito-posterior positions.", "content": "Some points in the aetiology and mechanism of occipito-posterior positions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983814"}
{"pmid": "20983815", "title": "The management of the occipitoposterior presentation.", "content": "The management of the occipitoposterior presentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983815"}
{"pmid": "20983816", "title": "Further observations on the Rh and Hr factors, and the blood group frequencies in Papuans.", "content": "Further observations on the Rh and Hr factors, and the blood group frequencies in Papuans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983816"}
{"pmid": "20983817", "title": "The treatment of hospital blankets with oil emulsions and the bactericidal action of fixanol C (cetyl pyridinium bromide).", "content": "The treatment of hospital blankets with oil emulsions and the bactericidal action of fixanol C (cetyl pyridinium bromide).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983817"}
{"pmid": "20983818", "title": "Notes on Field's stain.", "content": "Notes on Field's stain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983818"}
{"pmid": "20983819", "title": "Spinal anaesthesia and chloroform; a comparison of mortality.", "content": "Spinal anaesthesia and chloroform; a comparison of mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983819"}
{"pmid": "20983820", "title": "The bleeding tendency in obstructive jaundice; diagnosis and management.", "content": "The bleeding tendency in obstructive jaundice; diagnosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983820"}
{"pmid": "20983821", "title": "The basic wage, shortage of nurses and social medicine.", "content": "The basic wage, shortage of nurses and social medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983821"}
{"pmid": "20983822", "title": "Report of a case of amicrobic pyuria.", "content": "Report of a case of amicrobic pyuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983822"}
{"pmid": "20983823", "title": "Report on a case of burns complicated by haematemesis and melena.", "content": "Report on a case of burns complicated by haematemesis and melena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983823"}
{"pmid": "20983824", "title": "THORACIC complications of typhoid and Salmonella infections.", "content": "THORACIC complications of typhoid and Salmonella infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983824"}
{"pmid": "20983825", "title": "Blood group frequencies in Hollanders.", "content": "Blood group frequencies in Hollanders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983825"}
{"pmid": "20983826", "title": "Observations on human leprosy; infection of rats with human excretal organisms.", "content": "Observations on human leprosy; infection of rats with human excretal organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983826"}
{"pmid": "20983827", "title": "The botany of Toowoomba and environs and its relation to clinical allergy of the upper respiratory tract.", "content": "The botany of Toowoomba and environs and its relation to clinical allergy of the upper respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983827"}
{"pmid": "20983828", "title": "Sudden death following initial injection of a mercurial diuretic.", "content": "Sudden death following initial injection of a mercurial diuretic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983828"}
{"pmid": "20983829", "title": "Latent primary breast tumour.", "content": "Latent primary breast tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983829"}
{"pmid": "20983830", "title": "BONE as human food.", "content": "BONE as human food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983830"}
{"pmid": "20983831", "title": "The changing face of medical practice in Tasmania.", "content": "The changing face of medical practice in Tasmania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983831"}
{"pmid": "20983832", "title": "Experimental observations on the aural effects of gunblast.", "content": "Experimental observations on the aural effects of gunblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983832"}
{"pmid": "20983833", "title": "The value of biochemical tests in the interpretation of jaundice.", "content": "The value of biochemical tests in the interpretation of jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983833"}
{"pmid": "20983834", "title": "Medical rehabilitation; its organization in the Royal Air Force and the Royal Australian Air Force.", "content": "Medical rehabilitation; its organization in the Royal Air Force and the Royal Australian Air Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983834"}
{"pmid": "20983835", "title": "The resistance of Haemophilus influenzae to the action of penicillin, with special reference to type B strains.", "content": "The resistance of Haemophilus influenzae to the action of penicillin, with special reference to type B strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983835"}
{"pmid": "20983837", "title": "Poliomyelitis.", "content": "Poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983837"}
{"pmid": "20983836", "title": "A trocar and cannula for the intravenous administration of fluids.", "content": "A trocar and cannula for the intravenous administration of fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983836"}
{"pmid": "20983838", "title": "Congenital abnormalities in infants following infectious diseases during pregnancy, with special reference to rubella; third series of cases.", "content": "Congenital abnormalities in infants following infectious diseases during pregnancy, with special reference to rubella; third series of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983838"}
{"pmid": "20983839", "title": "Coeliac disease; a survey from the Children's Hospital, Melbourne.", "content": "Coeliac disease; a survey from the Children's Hospital, Melbourne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983839"}
{"pmid": "20983840", "title": "Spondylitis ankylopoietica.", "content": "Spondylitis ankylopoietica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983840"}
{"pmid": "20983841", "title": "The tuberculosis service.", "content": "The tuberculosis service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983841"}
{"pmid": "20983842", "title": "The treatment of cholecystitis.", "content": "The treatment of cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983842"}
{"pmid": "20983843", "title": "Methods of treatment of the psychoses.", "content": "Methods of treatment of the psychoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983843"}
{"pmid": "20983844", "title": "Radiotherapy in carcinoma of the cervix uteri.", "content": "Radiotherapy in carcinoma of the cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983844"}
{"pmid": "20983845", "title": "Acute appendicitis.", "content": "Acute appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983845"}
{"pmid": "20983846", "title": "Some useful minor surgery.", "content": "Some useful minor surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983846"}
{"pmid": "20983847", "title": "Surgical relief of hypertension.", "content": "Surgical relief of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983847"}
{"pmid": "20983848", "title": "Some aspects of sterility.", "content": "Some aspects of sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983848"}
{"pmid": "20983849", "title": "Squint.", "content": "Squint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983849"}
{"pmid": "20983850", "title": "Some modern trends in dermatology.", "content": "Some modern trends in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983850"}
{"pmid": "20983851", "title": "The surgery of arterial obstruction.", "content": "The surgery of arterial obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983851"}
{"pmid": "20983873", "title": "Diagnosis and treatment of rectal and sigmoid polyps.", "content": "Diagnosis and treatment of rectal and sigmoid polyps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983873"}
{"pmid": "20983872", "title": "Cystic fibrosis of the pancreas.", "content": "Cystic fibrosis of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983872"}
{"pmid": "20983874", "title": "Spontaneous pneumothorax; case report.", "content": "Spontaneous pneumothorax; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983874"}
{"pmid": "20983875", "title": "Intestinal obstruction.", "content": "Intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983875"}
{"pmid": "20983876", "title": "Tuberculosis laríngea.", "content": "Tuberculosis laríngea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983876"}
{"pmid": "20983877", "title": "Hepatolenticular degeneration; nutritional factors: observations on methionine and high-protein diets.", "content": "Hepatolenticular degeneration; nutritional factors: observations on methionine and high-protein diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983877"}
{"pmid": "20983878", "title": "Cardiac arrest after spinal anesthesia; report of a case with recovery.", "content": "Cardiac arrest after spinal anesthesia; report of a case with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983878"}
{"pmid": "20983879", "title": "Malignant lymphoma (giant-follicle type) of jejunum, mesentery and omentum.", "content": "Malignant lymphoma (giant-follicle type) of jejunum, mesentery and omentum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983879"}
{"pmid": "20983880", "title": "Adenocarcinoma of ascending colon.", "content": "Adenocarcinoma of ascending colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983880"}
{"pmid": "20983881", "title": "Ether inhalers in early use.", "content": "Ether inhalers in early use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983881"}
{"pmid": "20983882", "title": "Health bills pending in Congress.", "content": "Health bills pending in Congress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983882"}
{"pmid": "20983883", "title": "Normal growth and development during adolescence.", "content": "Normal growth and development during adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983883"}
{"pmid": "20983884", "title": "Carcinoma of cardia of stomach.", "content": "Carcinoma of cardia of stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983884"}
{"pmid": "20983885", "title": "Gastric ulcer, acute.", "content": "Gastric ulcer, acute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983885"}
{"pmid": "20983886", "title": "GAMMA globulin in acute hepatitis.", "content": "GAMMA globulin in acute hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983886"}
{"pmid": "20983887", "title": "Recent advances in x-ray diagnosis in injuries of the wrist joint and hand.", "content": "Recent advances in x-ray diagnosis in injuries of the wrist joint and hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983887"}
{"pmid": "20983888", "title": "Cystoscopic instrument.", "content": "Cystoscopic instrument.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983888"}
{"pmid": "20983889", "title": "Arthritis, gastrointestinal symptoms and neurodermatitis as vasomotor reactions.", "content": "Arthritis, gastrointestinal symptoms and neurodermatitis as vasomotor reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983889"}
{"pmid": "20983890", "title": "Study and treatment of infants diseases in the U.S.S.R.", "content": "Study and treatment of infants diseases in the U.S.S.R.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983890"}
{"pmid": "20983891", "title": "Overweight; is it glands or is it appetite?", "content": "Overweight; is it glands or is it appetite?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983891"}
{"pmid": "20983892", "title": "Case histories of malpractice actions against physicians.", "content": "Case histories of malpractice actions against physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983892"}
{"pmid": "20983893", "title": "Management of acute congestive heart failure.", "content": "Management of acute congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983893"}
{"pmid": "20983894", "title": "Biliary disease in the elderly and chronically ill patient.", "content": "Biliary disease in the elderly and chronically ill patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983894"}
{"pmid": "20983895", "title": "Linear fracture of the skull across the venous sinuses.", "content": "Linear fracture of the skull across the venous sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983895"}
{"pmid": "20983896", "title": "A new hemoglobinometer; a no-blood-drop method, using the principle of transillumination.", "content": "A new hemoglobinometer; a no-blood-drop method, using the principle of transillumination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983896"}
{"pmid": "20983898", "title": "Postural headache and attacks of loss of tone in a case of calcified suprasellar tumor.", "content": "Postural headache and attacks of loss of tone in a case of calcified suprasellar tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983898"}
{"pmid": "20983897", "title": "Benzyl benzoate treatment of scabies in a staging area.", "content": "Benzyl benzoate treatment of scabies in a staging area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983897"}
{"pmid": "20983899", "title": "Internal hernia strangulated by Meckel's diverticulum.", "content": "Internal hernia strangulated by Meckel's diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983899"}
{"pmid": "20983900", "title": "Pneumonia of ornithotic origin; report of two cases occurring in the same family following contact with pigeons.", "content": "Pneumonia of ornithotic origin; report of two cases occurring in the same family following contact with pigeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983900"}
{"pmid": "20983901", "title": "Accurate diagnosis of silicosis: possible sources of error.", "content": "Accurate diagnosis of silicosis: possible sources of error.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983901"}
{"pmid": "20983902", "title": "Facing the future in medicine.", "content": "Facing the future in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983902"}
{"pmid": "20983904", "title": "The cross-eyed child.", "content": "The cross-eyed child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983904"}
{"pmid": "20983903", "title": "Brucellosis.", "content": "Brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983903"}
{"pmid": "20983905", "title": "Tuberculomata of liver with case report.", "content": "Tuberculomata of liver with case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983905"}
{"pmid": "20983906", "title": "Squamous cell carcinoma of the cervix uteri complicated by malaria introduced by a transfusion from a returned veteran.", "content": "Squamous cell carcinoma of the cervix uteri complicated by malaria introduced by a transfusion from a returned veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983906"}
{"pmid": "20983907", "title": "Colonial medical service in Nigeria.", "content": "Colonial medical service in Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983907"}
{"pmid": "20983908", "title": "Physical fitness, the step test.", "content": "Physical fitness, the step test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983908"}
{"pmid": "20983909", "title": "Syphilis of the stomach; with a case report.", "content": "Syphilis of the stomach; with a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983909"}
{"pmid": "20983910", "title": "Endocrine therapy of enuresis.", "content": "Endocrine therapy of enuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983910"}
{"pmid": "20983911", "title": "Physiotherapy's position in public health.", "content": "Physiotherapy's position in public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983911"}
{"pmid": "20983912", "title": "Diagnosis and treatment of eczema.", "content": "Diagnosis and treatment of eczema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983912"}
{"pmid": "20983913", "title": "Gastro-intestinal suction.", "content": "Gastro-intestinal suction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983913"}
{"pmid": "20983914", "title": "Recent developments in wound antiseptics.", "content": "Recent developments in wound antiseptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983914"}
{"pmid": "20983915", "title": "Preserving mineral waters; a letter of 1735 from Stephen Hales.", "content": "Preserving mineral waters; a letter of 1735 from Stephen Hales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983915"}
{"pmid": "20983920", "title": "Recovery from blindness following removal of suprasellar epidermoid.", "content": "Recovery from blindness following removal of suprasellar epidermoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983920"}
{"pmid": "20983921", "title": "The treatment of agranulocytosis with penicillin: report of a case resulting from chrysotherapy for rheumatoid arthritis.", "content": "The treatment of agranulocytosis with penicillin: report of a case resulting from chrysotherapy for rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983921"}
{"pmid": "20983922", "title": "Use of vitamin A tolerance test in certain cases of dermatologic disorders.", "content": "Use of vitamin A tolerance test in certain cases of dermatologic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983922"}
{"pmid": "20983923", "title": "Small ulcerating lesions of the stomach; report of two cases.", "content": "Small ulcerating lesions of the stomach; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20983923"}
{"pmid": "20984027", "title": "The clinical aspects of middle meningeal haemorrhage.", "content": "The clinical aspects of middle meningeal haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984027"}
{"pmid": "20984028", "title": "The skin and the reticular tissue.", "content": "The skin and the reticular tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984028"}
{"pmid": "20984029", "title": "Sodium-bismuthyl-tartrate in the treatment of rheumatism.", "content": "Sodium-bismuthyl-tartrate in the treatment of rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984029"}
{"pmid": "20984030", "title": "Lymphogranuloma in the female.", "content": "Lymphogranuloma in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984030"}
{"pmid": "20984031", "title": "Obesity; its physiological basis.", "content": "Obesity; its physiological basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984031"}
{"pmid": "20984032", "title": "The use of penicillin in the treatment of compound fractures.", "content": "The use of penicillin in the treatment of compound fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984032"}
{"pmid": "20984033", "title": "Practical anaesthesia.", "content": "Practical anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984033"}
{"pmid": "20984034", "title": "Vitamin B in the treatment of syphilis.", "content": "Vitamin B in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984034"}
{"pmid": "20984035", "title": "A report of three hundred and forty-two consecutive cases of appendicitis.", "content": "A report of three hundred and forty-two consecutive cases of appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984035"}
{"pmid": "20984036", "title": "Non-surgical management of postpneumonic empyema.", "content": "Non-surgical management of postpneumonic empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984036"}
{"pmid": "20984037", "title": "Dysgerminoma.", "content": "Dysgerminoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984037"}
{"pmid": "20984074", "title": "Urinary symptoms of heat-stroke.", "content": "Urinary symptoms of heat-stroke.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984074"}
{"pmid": "20984073", "title": "Studies in poliomyelitis; the study of an outbreak of poliomyelitis occurring in a suburb of Johannesburg.", "content": "Studies in poliomyelitis; the study of an outbreak of poliomyelitis occurring in a suburb of Johannesburg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984073"}
{"pmid": "20984075", "title": "Foreign body in the lung.", "content": "Foreign body in the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984075"}
{"pmid": "20984076", "title": "Two cases of rupture of the bulbous urethra treated unconventionally.", "content": "Two cases of rupture of the bulbous urethra treated unconventionally.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984076"}
{"pmid": "20984077", "title": "Fenestration for otosclerosis; the transtympanic approach.", "content": "Fenestration for otosclerosis; the transtympanic approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984077"}
{"pmid": "20984078", "title": "Studies in poliomyelitis; the isolation of the virus of poliomyelitis from sewage in Johannesburg.", "content": "Studies in poliomyelitis; the isolation of the virus of poliomyelitis from sewage in Johannesburg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984078"}
{"pmid": "20984079", "title": "New hope for spinal cord sufferers.", "content": "New hope for spinal cord sufferers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984079"}
{"pmid": "20984080", "title": "The public health cure of bilharziasis with one-day course of antimony.", "content": "The public health cure of bilharziasis with one-day course of antimony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984080"}
{"pmid": "20984081", "title": "Should babies be consulted about their diets?", "content": "Should babies be consulted about their diets?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984081"}
{"pmid": "20984084", "title": "Some aspects of current housing problems.", "content": "Some aspects of current housing problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984084"}
{"pmid": "20984083", "title": "Primary myopathy characterized by micropygia in the first generation and a scapulo-humeral dystrophy in the second one of consanguineous parents.", "content": "Primary myopathy characterized by micropygia in the first generation and a scapulo-humeral dystrophy in the second one of consanguineous parents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984083"}
{"pmid": "20984085", "title": "The need for the establishment of a division of criminal science in the Department of Justice of the Union Government.", "content": "The need for the establishment of a division of criminal science in the Department of Justice of the Union Government.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984085"}
{"pmid": "20984086", "title": "The granulosa-cell tumour; a review of the literature and a theory as to its pathogenesis.", "content": "The granulosa-cell tumour; a review of the literature and a theory as to its pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984086"}
{"pmid": "20984088", "title": "Boxing injuries.", "content": "Boxing injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984088"}
{"pmid": "20984087", "title": "Fractures of the skull involving the frontal air sinuses due to localised violence; a study of 30 cases.", "content": "Fractures of the skull involving the frontal air sinuses due to localised violence; a study of 30 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984087"}
{"pmid": "20984089", "title": "Report on 14 consecutive cases of tendon suture.", "content": "Report on 14 consecutive cases of tendon suture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984089"}
{"pmid": "20984133", "title": "Transthoracic resection of the cardia and esophagus.", "content": "Transthoracic resection of the cardia and esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984133"}
{"pmid": "20984134", "title": "The use of pentothal sodium in thyroid surgery.", "content": "The use of pentothal sodium in thyroid surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984134"}
{"pmid": "20984136", "title": "The management of nonspecific urinary tract infections.", "content": "The management of nonspecific urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984136"}
{"pmid": "20984135", "title": "Central bone tumors.", "content": "Central bone tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984135"}
{"pmid": "20984137", "title": "The use and abuse of sulfonamides in dermatologic conditions.", "content": "The use and abuse of sulfonamides in dermatologic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984137"}
{"pmid": "20984138", "title": "Sulfonamide therapy of Vincent's angina.", "content": "Sulfonamide therapy of Vincent's angina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984138"}
{"pmid": "20984139", "title": "Obstetrics in the postwar years.", "content": "Obstetrics in the postwar years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984139"}
{"pmid": "20984140", "title": "Gastro-intestinal lymphosarcoma; diagnostic and therapeutic problems.", "content": "Gastro-intestinal lymphosarcoma; diagnostic and therapeutic problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984140"}
{"pmid": "20984141", "title": "Albers-Schönberg disease affecting a soldier.", "content": "Albers-Schönberg disease affecting a soldier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984141"}
{"pmid": "20984142", "title": "Taylor combination oxygen tents for administration of oxygen to infants, children, and adults.", "content": "Taylor combination oxygen tents for administration of oxygen to infants, children, and adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984142"}
{"pmid": "20984143", "title": "The application of the principles of military surgery to civilian practice.", "content": "The application of the principles of military surgery to civilian practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984143"}
{"pmid": "20984144", "title": "Antibiotics.", "content": "Antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984144"}
{"pmid": "20984145", "title": "The relationship between the toxicity, potency, acquired sensitivity and the chemical structure of some local anaesthetics.", "content": "The relationship between the toxicity, potency, acquired sensitivity and the chemical structure of some local anaesthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984145"}
{"pmid": "20984146", "title": "Transthoracic vagotomy for peptic ulcer.", "content": "Transthoracic vagotomy for peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984146"}
{"pmid": "20984149", "title": "Management of psychotic patients in a general hospital in Pacific area; a study of 155 consecutive admissions.", "content": "Management of psychotic patients in a general hospital in Pacific area; a study of 155 consecutive admissions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984149"}
{"pmid": "20984148", "title": "Chorio-epithelioma with herpes gestationis; report of a case.", "content": "Chorio-epithelioma with herpes gestationis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984148"}
{"pmid": "20984147", "title": "Delayed tonsillar hemorrhage.", "content": "Delayed tonsillar hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984147"}
{"pmid": "20984150", "title": "Sporotrichosis; report of a case in Virginia.", "content": "Sporotrichosis; report of a case in Virginia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984150"}
{"pmid": "20984152", "title": "Foreign bodies in the vagina.", "content": "Foreign bodies in the vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984152"}
{"pmid": "20984151", "title": "Certain factors to be considered in the surgical thyroid.", "content": "Certain factors to be considered in the surgical thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984151"}
{"pmid": "20984153", "title": "Five cases of latent trichophyton infection activated by the use of penicillin.", "content": "Five cases of latent trichophyton infection activated by the use of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984153"}
{"pmid": "20984154", "title": "Headache and head injuries.", "content": "Headache and head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984154"}
{"pmid": "20984156", "title": "Duodenal ileus.", "content": "Duodenal ileus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984156"}
{"pmid": "20984155", "title": "Cure by music.", "content": "Cure by music.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984155"}
{"pmid": "20984157", "title": "Oesophageal hiatus hernia.", "content": "Oesophageal hiatus hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984157"}
{"pmid": "20984158", "title": "Recurrent depression and virilism.", "content": "Recurrent depression and virilism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984158"}
{"pmid": "20984159", "title": "Friedländer's pneumonia with complications requiring special treatment.", "content": "Friedländer's pneumonia with complications requiring special treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984159"}
{"pmid": "20984160", "title": "Dercum's disease.", "content": "Dercum's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984160"}
{"pmid": "20984161", "title": "Chondromatosis.", "content": "Chondromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984161"}
{"pmid": "20984162", "title": "Primary omental torsion; clinical aspects (with case report).", "content": "Primary omental torsion; clinical aspects (with case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984162"}
{"pmid": "20984163", "title": "Surgical diseases of the lung.", "content": "Surgical diseases of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984163"}
{"pmid": "20984164", "title": "REVISED treatment schedules for syphilis.", "content": "REVISED treatment schedules for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984164"}
{"pmid": "20984165", "title": "INSECT-BORNE diseases during World War II.", "content": "INSECT-BORNE diseases during World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984165"}
{"pmid": "20984167", "title": "CHANGES in human muscle after denervation.", "content": "CHANGES in human muscle after denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984167"}
{"pmid": "20984166", "title": "SURVIVAL of men immersed in the ocean.", "content": "SURVIVAL of men immersed in the ocean.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984166"}
{"pmid": "20984168", "title": "METHOD of procuring anaerobic plates.", "content": "METHOD of procuring anaerobic plates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984168"}
{"pmid": "20984169", "title": "PHYSICAL therapy management of lower extremity amputees.", "content": "PHYSICAL therapy management of lower extremity amputees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984169"}
{"pmid": "20984170", "title": "SOMATIZATION reactions.", "content": "SOMATIZATION reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984170"}
{"pmid": "20984171", "title": "NONULCER dyspepsia in soldiers.", "content": "NONULCER dyspepsia in soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984171"}
{"pmid": "20984172", "title": "PROPER VACCINATION, the only method to prevent smallpox.", "content": "PROPER VACCINATION, the only method to prevent smallpox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984172"}
{"pmid": "20984173", "title": "ARMY rheumatism centers.", "content": "ARMY rheumatism centers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984173"}
{"pmid": "20984174", "title": "Chemotherapy and the hemolytic Streptococcus carrier state.", "content": "Chemotherapy and the hemolytic Streptococcus carrier state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984174"}
{"pmid": "20984175", "title": "The preoperative care of battle casualties.", "content": "The preoperative care of battle casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984175"}
{"pmid": "20984176", "title": "Schistosomiasis japonica; laboratory diagnosis.", "content": "Schistosomiasis japonica; laboratory diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984176"}
{"pmid": "20984177", "title": "Field garbage incineration.", "content": "Field garbage incineration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984177"}
{"pmid": "20984178", "title": "Treatment of fracture of shaft of femur.", "content": "Treatment of fracture of shaft of femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984178"}
{"pmid": "20984179", "title": "Nutrition survey in Pacific Theater of Operations.", "content": "Nutrition survey in Pacific Theater of Operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984179"}
{"pmid": "20984180", "title": "Sodium amytal in treatment of aphasia; preliminary report.", "content": "Sodium amytal in treatment of aphasia; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984180"}
{"pmid": "20984181", "title": "Early syphilis of the submaxillary glands.", "content": "Early syphilis of the submaxillary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984181"}
{"pmid": "20984182", "title": "An orthopedic service during a campaign in Italy.", "content": "An orthopedic service during a campaign in Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984182"}
{"pmid": "20984183", "title": "Tour of inspection of pack.", "content": "Tour of inspection of pack.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984183"}
{"pmid": "20984184", "title": "Carotid sinus syndrome in air crew personnel.", "content": "Carotid sinus syndrome in air crew personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984184"}
{"pmid": "20984185", "title": "An unusual typhoid carrier.", "content": "An unusual typhoid carrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984185"}
{"pmid": "20984186", "title": "Closed fractures of leg and ankle.", "content": "Closed fractures of leg and ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984186"}
{"pmid": "20984187", "title": "PARENTERAL fluids.", "content": "PARENTERAL fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984187"}
{"pmid": "20984188", "title": "SURGERY in the combat zone.", "content": "SURGERY in the combat zone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984188"}
{"pmid": "20984189", "title": "MILITARY control of insect and snail borne diseases.", "content": "MILITARY control of insect and snail borne diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984189"}
{"pmid": "20984190", "title": "VALUE of convalescent reconditioning.", "content": "VALUE of convalescent reconditioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984190"}
{"pmid": "20984191", "title": "STANDARD operating procedure for control of malaria and other insect-borne diseases during a combat operation.", "content": "STANDARD operating procedure for control of malaria and other insect-borne diseases during a combat operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984191"}
{"pmid": "20984192", "title": "REACTIONS attributed to atabrine.", "content": "REACTIONS attributed to atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984192"}
{"pmid": "20984193", "title": "TRENCH foot and preparation for wet cold.", "content": "TRENCH foot and preparation for wet cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984193"}
{"pmid": "20984194", "title": "A note on blood sedimentation rates.", "content": "A note on blood sedimentation rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984194"}
{"pmid": "20984195", "title": "Organization of a shock service in a combat area hospital.", "content": "Organization of a shock service in a combat area hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984195"}
{"pmid": "20984197", "title": "INFLAMMATORY dermatoses in the western and southwestern Pacific areas, with special reference to treatment.", "content": "INFLAMMATORY dermatoses in the western and southwestern Pacific areas, with special reference to treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984197"}
{"pmid": "20984196", "title": "Use of dimethylphthalate impregnated clothing as protection against scrub typhus.", "content": "Use of dimethylphthalate impregnated clothing as protection against scrub typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984196"}
{"pmid": "20984198", "title": "Eosinophilia, ankylostomiasis and strongyloidosis in the south Pacific area.", "content": "Eosinophilia, ankylostomiasis and strongyloidosis in the south Pacific area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984198"}
{"pmid": "20984199", "title": "Apparatus for cleaning blood count pipettes.", "content": "Apparatus for cleaning blood count pipettes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984199"}
{"pmid": "20984200", "title": "Iso-amyl alcohol as a dehydrating agent in the preparation of mosquito larvae and larval exuviae slides.", "content": "Iso-amyl alcohol as a dehydrating agent in the preparation of mosquito larvae and larval exuviae slides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984200"}
{"pmid": "20984201", "title": "INSECT and rodent control supplies.", "content": "INSECT and rodent control supplies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984201"}
{"pmid": "20984202", "title": "An epidemiological study of schistosomiasis japonica.", "content": "An epidemiological study of schistosomiasis japonica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984202"}
{"pmid": "20984203", "title": "The use of hydrocoloids in full denture impressions.", "content": "The use of hydrocoloids in full denture impressions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984203"}
{"pmid": "20984219", "title": "[Therapeutical aid in the Red Army].", "content": "[Therapeutical aid in the Red Army].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984219"}
{"pmid": "20984220", "title": "[Against frequent dressing of wounds].", "content": "[Against frequent dressing of wounds].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984220"}
{"pmid": "20984221", "title": "[Epidemic control in offense operations in Pribaltic].", "content": "[Epidemic control in offense operations in Pribaltic].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984221"}
{"pmid": "20984222", "title": "[Gas infection after the data of S.F.A.].", "content": "[Gas infection after the data of S.F.A.].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984222"}
{"pmid": "20984223", "title": "[Diseases of the cardiovascular system].", "content": "[Diseases of the cardiovascular system].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984223"}
{"pmid": "20984224", "title": "VEGETABLE ghee.", "content": "VEGETABLE ghee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984224"}
{"pmid": "20984225", "title": "D.D.T., 666 and insect pests of stored grains.", "content": "D.D.T., 666 and insect pests of stored grains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984225"}
{"pmid": "20984226", "title": "A museum of evolution.", "content": "A museum of evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984226"}
{"pmid": "20984227", "title": "Chemistry of kurchi seeds; isolation of a crystalline glyco-alkaloid.", "content": "Chemistry of kurchi seeds; isolation of a crystalline glyco-alkaloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984227"}
{"pmid": "20984228", "title": "Spectrophotometric determinations of iron and cobalt using isonitrosodimethyldihydroresorcinol.", "content": "Spectrophotometric determinations of iron and cobalt using isonitrosodimethyldihydroresorcinol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984228"}
{"pmid": "20984229", "title": "Supplemental value of bran extract in penicillin production.", "content": "Supplemental value of bran extract in penicillin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984229"}
{"pmid": "20984230", "title": "Cytochemical studies of avitaminosis in toddy yeast.", "content": "Cytochemical studies of avitaminosis in toddy yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984230"}
{"pmid": "20984231", "title": "On a protozoan parasite, Myxobolus mrigalae Chakravarty, found infesting the fry of Cirrhina mrigala (Ham.).", "content": "On a protozoan parasite, Myxobolus mrigalae Chakravarty, found infesting the fry of Cirrhina mrigala (Ham.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984231"}
{"pmid": "20984232", "title": "The somatic and meiotic chromosomes of Commelina benghalensis Linn.", "content": "The somatic and meiotic chromosomes of Commelina benghalensis Linn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984232"}
{"pmid": "20984233", "title": "The construction and installation of thermocouples for biological research.", "content": "The construction and installation of thermocouples for biological research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984233"}
{"pmid": "20984234", "title": "Radio-frequency heating.", "content": "Radio-frequency heating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984234"}
{"pmid": "20984235", "title": "Some war-time biological books in French.", "content": "Some war-time biological books in French.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984235"}
{"pmid": "20984236", "title": "Genetics of the microfungi.", "content": "Genetics of the microfungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984236"}
{"pmid": "20984237", "title": "Is carotene a provitamin A, or has it biological activity per se?", "content": "Is carotene a provitamin A, or has it biological activity per se?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984237"}
{"pmid": "20984238", "title": "Microbiological assay of amino-acids with Leuconostoc mesenteroides P. 60.", "content": "Microbiological assay of amino-acids with Leuconostoc mesenteroides P. 60.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984238"}
{"pmid": "20984239", "title": "Fractionation of human plasma with ether.", "content": "Fractionation of human plasma with ether.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984239"}
{"pmid": "20984240", "title": "Anterior process of the malleus in rodents.", "content": "Anterior process of the malleus in rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984240"}
{"pmid": "20984241", "title": "Present state of some German museums.", "content": "Present state of some German museums.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984241"}
{"pmid": "20984242", "title": "BLOOD cells of an insect.", "content": "BLOOD cells of an insect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984242"}
{"pmid": "20984243", "title": "INTERNATIONAL co-operation.", "content": "INTERNATIONAL co-operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984243"}
{"pmid": "20984244", "title": "Control of atomic energy.", "content": "Control of atomic energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984244"}
{"pmid": "20984245", "title": "An estimate of the age of the earth.", "content": "An estimate of the age of the earth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984245"}
{"pmid": "20984246", "title": "Detection of manganese deficiency in plants by tissue tests, using tetramethyldiaminodiphenylmethane.", "content": "Detection of manganese deficiency in plants by tissue tests, using tetramethyldiaminodiphenylmethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984246"}
{"pmid": "20984247", "title": "Determination of dienoestrol in biological samples.", "content": "Determination of dienoestrol in biological samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984247"}
{"pmid": "20984248", "title": "Cytological localization of riboflavin (vitamin B2) and thiamin (vitamin B1) by fluorescence microspectrography.", "content": "Cytological localization of riboflavin (vitamin B2) and thiamin (vitamin B1) by fluorescence microspectrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984248"}
{"pmid": "20984249", "title": "Maximum rate of selection for dominant quantitative genes.", "content": "Maximum rate of selection for dominant quantitative genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984249"}
{"pmid": "20984256", "title": "On the theory of scales of measurement.", "content": "On the theory of scales of measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984256"}
{"pmid": "20984250", "title": "Artificial fertilization of cod (Gadus callarias Linn.) at Port Erin.", "content": "Artificial fertilization of cod (Gadus callarias Linn.) at Port Erin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984250"}
{"pmid": "20984257", "title": "The activity of synthetic folic acid in purified rations for the chick.", "content": "The activity of synthetic folic acid in purified rations for the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984257"}
{"pmid": "20984258", "title": "Fluctuations in abundance of marine animals.", "content": "Fluctuations in abundance of marine animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984258"}
{"pmid": "20984259", "title": "Hyaluronidase inhibition by sodium salicylate in rheumatic fever.", "content": "Hyaluronidase inhibition by sodium salicylate in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984259"}
{"pmid": "20984260", "title": "H.R. 6448.", "content": "H.R. 6448.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984260"}
{"pmid": "20984261", "title": "Proposal for an American Institute of Biology.", "content": "Proposal for an American Institute of Biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984261"}
{"pmid": "20984263", "title": "Virus variation in relation to the cancer problem.", "content": "Virus variation in relation to the cancer problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984263"}
{"pmid": "20984262", "title": "Geopathology or ethnopathology?", "content": "Geopathology or ethnopathology?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984262"}
{"pmid": "20984264", "title": "Experimental psychology and ethics.", "content": "Experimental psychology and ethics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984264"}
{"pmid": "20984270", "title": "The ego of homosexuals.", "content": "The ego of homosexuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984270"}
{"pmid": "20984271", "title": "A contribution to the study of the masturbation phantasy.", "content": "A contribution to the study of the masturbation phantasy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984271"}
{"pmid": "20984269", "title": "Further notes on the implications of psycho-analysis: metapsychology and personology.", "content": "Further notes on the implications of psycho-analysis: metapsychology and personology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984269"}
{"pmid": "20984272", "title": "Primitive emotional development.", "content": "Primitive emotional development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984272"}
{"pmid": "20984273", "title": "Some aspects of phantasy in relation to general psychology.", "content": "Some aspects of phantasy in relation to general psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984273"}
{"pmid": "20984274", "title": "An unwelcome child and her death instinct.", "content": "An unwelcome child and her death instinct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984274"}
{"pmid": "20984275", "title": "On the view that repressed fear of severance of the genitalia is solely caused by external reality and is not inherited.", "content": "On the view that repressed fear of severance of the genitalia is solely caused by external reality and is not inherited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984275"}
{"pmid": "20984276", "title": "A short contribution to the problem of simulation of insanity.", "content": "A short contribution to the problem of simulation of insanity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984276"}
{"pmid": "20984277", "title": "Prohibitions against the simultaneous consumption of milk and flesh in orthodox Jewish law.", "content": "Prohibitions against the simultaneous consumption of milk and flesh in orthodox Jewish law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984277"}
{"pmid": "20984278", "title": "Concerning art and metapsychology.", "content": "Concerning art and metapsychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984278"}
{"pmid": "20984280", "title": "The intensity of an attitude.", "content": "The intensity of an attitude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984280"}
{"pmid": "20984279", "title": "On the mechanism of suggestion and hypnosis.", "content": "On the mechanism of suggestion and hypnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984279"}
{"pmid": "20984281", "title": "Two experiments with an anti-Semitism poll.", "content": "Two experiments with an anti-Semitism poll.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984281"}
{"pmid": "20984282", "title": "A basic deception in exhibitions of hypnosis.", "content": "A basic deception in exhibitions of hypnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984282"}
{"pmid": "20984283", "title": "A re-examination of correlations between lynchings and economic indices.", "content": "A re-examination of correlations between lynchings and economic indices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984283"}
{"pmid": "20984284", "title": "Two years under a false name.", "content": "Two years under a false name.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984284"}
{"pmid": "20984285", "title": "Bombing mission number fifteen.", "content": "Bombing mission number fifteen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984285"}
{"pmid": "20984286", "title": "Counseling of emotional blocking in an aviator.", "content": "Counseling of emotional blocking in an aviator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984286"}
{"pmid": "20984287", "title": "Report on an interesting fugue.", "content": "Report on an interesting fugue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984287"}
{"pmid": "20984289", "title": "Deviations of Wechsler-Bellevue subtest scores from vocabulary level in superior adults.", "content": "Deviations of Wechsler-Bellevue subtest scores from vocabulary level in superior adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984289"}
{"pmid": "20984290", "title": "Late effects of closed head injuries; psychiatric observations.", "content": "Late effects of closed head injuries; psychiatric observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984290"}
{"pmid": "20984288", "title": "A mental pattern found in motor deviates.", "content": "A mental pattern found in motor deviates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984288"}
{"pmid": "20984291", "title": "Some clinical applications of the Rey-Davis Performance Test.", "content": "Some clinical applications of the Rey-Davis Performance Test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984291"}
{"pmid": "20984292", "title": "Marriage and mental disease; a study in social psychopathology.", "content": "Marriage and mental disease; a study in social psychopathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984292"}
{"pmid": "20984293", "title": "Psychological investigation of a group of internees at Belsen Camp.", "content": "Psychological investigation of a group of internees at Belsen Camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984293"}
{"pmid": "20984294", "title": "Post-choreic personality and neurosis.", "content": "Post-choreic personality and neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984294"}
{"pmid": "20984295", "title": "Preliminary tuberculosis survey in a mental hospital.", "content": "Preliminary tuberculosis survey in a mental hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984295"}
{"pmid": "20984296", "title": "Seven hundred and fifty psychoneurotics and ten weeks' fly-bombing.", "content": "Seven hundred and fifty psychoneurotics and ten weeks' fly-bombing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984296"}
{"pmid": "20984297", "title": "A comparative study of disease incidence in admissions to a base psychiatric hospital in the Middle East.", "content": "A comparative study of disease incidence in admissions to a base psychiatric hospital in the Middle East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984297"}
{"pmid": "20984298", "title": "A comparison of prolonged narcosis and convulsion therapy in mental disorder.", "content": "A comparison of prolonged narcosis and convulsion therapy in mental disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984298"}
{"pmid": "20984299", "title": "Electrical convulsion therapy in 500 selected psychotics.", "content": "Electrical convulsion therapy in 500 selected psychotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984299"}
{"pmid": "20984300", "title": "Autonomic activity and induced convulsions.", "content": "Autonomic activity and induced convulsions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984300"}
{"pmid": "20984301", "title": "Ageing and senility; a major problem of psychiatry.", "content": "Ageing and senility; a major problem of psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984301"}
{"pmid": "20984302", "title": "The psychological aspects of ageing and senility.", "content": "The psychological aspects of ageing and senility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984302"}
{"pmid": "20984303", "title": "Social aspects of ageing and senility.", "content": "Social aspects of ageing and senility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984303"}
{"pmid": "20984304", "title": "Drug treatment in epilepsy.", "content": "Drug treatment in epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984304"}
{"pmid": "20984305", "title": "Thalamic degeneration following bilateral premotor frontal lobe atrophy of the Strümpell type.", "content": "Thalamic degeneration following bilateral premotor frontal lobe atrophy of the Strümpell type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984305"}
{"pmid": "20984306", "title": "Static tremor in anxiety states.", "content": "Static tremor in anxiety states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984306"}
{"pmid": "20984307", "title": "Recommendations for the design and performance of electroencephalographic apparatus.", "content": "Recommendations for the design and performance of electroencephalographic apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984307"}
{"pmid": "20984309", "title": "Investigation of vestibular function after head injury.", "content": "Investigation of vestibular function after head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984309"}
{"pmid": "20984308", "title": "Rhythmic slow discharges in the electroencephalogram.", "content": "Rhythmic slow discharges in the electroencephalogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984308"}
{"pmid": "20984315", "title": "The effect of exercise on soldiers with neurocirculatory asthenia.", "content": "The effect of exercise on soldiers with neurocirculatory asthenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984315"}
{"pmid": "20984323", "title": "Nummular keratitis and ocular brucellosis.", "content": "Nummular keratitis and ocular brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984323"}
{"pmid": "20984322", "title": "Recurrent aphthous uveitis with mucocutaneous lesions.", "content": "Recurrent aphthous uveitis with mucocutaneous lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984322"}
{"pmid": "20984324", "title": "Relation between illumination and visual efficiency.", "content": "Relation between illumination and visual efficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984324"}
{"pmid": "20984325", "title": "Photography of the external eye.", "content": "Photography of the external eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984325"}
{"pmid": "20984311", "title": "The effect of age, head resistance, and other physical factors on the stimulus threshold of electrically induced convulsions.", "content": "The effect of age, head resistance, and other physical factors on the stimulus threshold of electrically induced convulsions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984311"}
{"pmid": "20984327", "title": "Technical uses of air in ophthalmology.", "content": "Technical uses of air in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984327"}
{"pmid": "20984326", "title": "Method for biomicroscopic study of the conjunctival blood vessels.", "content": "Method for biomicroscopic study of the conjunctival blood vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984326"}
{"pmid": "20984316", "title": "A comparison of the exercise response in various groups of neurotic patients, and a method of rapid determination of oxygen in expired air, using a catharometer.", "content": "A comparison of the exercise response in various groups of neurotic patients, and a method of rapid determination of oxygen in expired air, using a catharometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984316"}
{"pmid": "20984312", "title": "Emotional factors in the course of pregnancy.", "content": "Emotional factors in the course of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984312"}
{"pmid": "20984313", "title": "Psychoendocrine relationships in pseudocyesis.", "content": "Psychoendocrine relationships in pseudocyesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984313"}
{"pmid": "20984328", "title": "Angioid streaks of the fundus oculi observed over a period of thirty-six years.", "content": "Angioid streaks of the fundus oculi observed over a period of thirty-six years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984328"}
{"pmid": "20984318", "title": "The therapy of peptic ulcer from the point of view of the internist.", "content": "The therapy of peptic ulcer from the point of view of the internist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984318"}
{"pmid": "20984329", "title": "Bitemporal defects in the visual fields resulting from developmental anomalies of the optic disks.", "content": "Bitemporal defects in the visual fields resulting from developmental anomalies of the optic disks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984329"}
{"pmid": "20984330", "title": "Studies on dark adaptation in military personnel complaining of night blindness.", "content": "Studies on dark adaptation in military personnel complaining of night blindness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984330"}
{"pmid": "20984319", "title": "Psychiatric treatment of peptic ulcer patients.", "content": "Psychiatric treatment of peptic ulcer patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984319"}
{"pmid": "20984314", "title": "A comparison of the exercise response in anxiety states and normal controls.", "content": "A comparison of the exercise response in anxiety states and normal controls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984314"}
{"pmid": "20984320", "title": "Relation of resentment and anger to functional gastric complaints.", "content": "Relation of resentment and anger to functional gastric complaints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984320"}
{"pmid": "20984331", "title": "Adult malformations of embryonic origin.", "content": "Adult malformations of embryonic origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984331"}
{"pmid": "20984332", "title": "Reconstruction of the eyelids and of the socket; report of a case.", "content": "Reconstruction of the eyelids and of the socket; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984332"}
{"pmid": "20984317", "title": "Counter-transference in the technique of medical practice.", "content": "Counter-transference in the technique of medical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984317"}
{"pmid": "20984333", "title": "Ocular manifestations of dermatologic diseases.", "content": "Ocular manifestations of dermatologic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984333"}
{"pmid": "20984321", "title": "The Harrower stress tolerance test.", "content": "The Harrower stress tolerance test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984321"}
{"pmid": "20984352", "title": "The ability to learn.", "content": "The ability to learn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984352"}
{"pmid": "20984353", "title": "Some consequences for history and psychology of Langmuir's concept of convergence and divergence of phenomena.", "content": "Some consequences for history and psychology of Langmuir's concept of convergence and divergence of phenomena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984353"}
{"pmid": "20984354", "title": "A note on the similarities and differences between projective tests and ability tests.", "content": "A note on the similarities and differences between projective tests and ability tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984354"}
{"pmid": "20984355", "title": "Present position of DDT in the control of insects of medical importance.", "content": "Present position of DDT in the control of insects of medical importance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984355"}
{"pmid": "20984356", "title": "The National Sanitation Foundation.", "content": "The National Sanitation Foundation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984356"}
{"pmid": "20984357", "title": "Frequency of hemolytic streptococci in the throats of well children in Dallas.", "content": "Frequency of hemolytic streptococci in the throats of well children in Dallas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984357"}
{"pmid": "20984358", "title": "Value of community health centers in preventive and curative medicine.", "content": "Value of community health centers in preventive and curative medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984358"}
{"pmid": "20984359", "title": "Some phases of school health services.", "content": "Some phases of school health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984359"}
{"pmid": "20984360", "title": "Epidemiology of venereal disease.", "content": "Epidemiology of venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984360"}
{"pmid": "20984361", "title": "Inactivation of poliomyelitis virus by free chlorine.", "content": "Inactivation of poliomyelitis virus by free chlorine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984361"}
{"pmid": "20984362", "title": "Antitoxin titers following immunization with protamineprecipitated diptheria toxoid.", "content": "Antitoxin titers following immunization with protamineprecipitated diptheria toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984362"}
{"pmid": "20984363", "title": "A selective medium for the isolation of Brucella suis.", "content": "A selective medium for the isolation of Brucella suis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984363"}
{"pmid": "20984364", "title": "DDT in the general health program.", "content": "DDT in the general health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984364"}
{"pmid": "20984371", "title": "An epidemic of food poisoning.", "content": "An epidemic of food poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984371"}
{"pmid": "20984380", "title": "Intra-abdominal bands in the scarless abdomen.", "content": "Intra-abdominal bands in the scarless abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984380"}
{"pmid": "20984381", "title": "Appendicitis in children; review of one thousand cases taken from the records of the Children's Hospital, Los Angeles.", "content": "Appendicitis in children; review of one thousand cases taken from the records of the Children's Hospital, Los Angeles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984381"}
{"pmid": "20984382", "title": "Uncomplicated prolapse of the ovary as a cause of acute abdominal pain.", "content": "Uncomplicated prolapse of the ovary as a cause of acute abdominal pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984382"}
{"pmid": "20984383", "title": "Intractable epistaxis of pregnancy.", "content": "Intractable epistaxis of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984383"}
{"pmid": "20984384", "title": "Biliary calculi with unusual x-ray findings.", "content": "Biliary calculi with unusual x-ray findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984384"}
{"pmid": "20984385", "title": "Fifty years of radiology; from Roentgen to the era of atomic power.", "content": "Fifty years of radiology; from Roentgen to the era of atomic power.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984385"}
{"pmid": "20984386", "title": "Acute pancreatitis.", "content": "Acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984386"}
{"pmid": "20984387", "title": "SUBTOTAL hysterectomy for cancer of the cervix and uterus.", "content": "SUBTOTAL hysterectomy for cancer of the cervix and uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984387"}
{"pmid": "20984388", "title": "The immunity of mice cured of trypanosome infections.", "content": "The immunity of mice cured of trypanosome infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984388"}
{"pmid": "20984389", "title": "On Coelomomyces fungi causing high mortality of Anopheles gambiae larvae in Rhodesia.", "content": "On Coelomomyces fungi causing high mortality of Anopheles gambiae larvae in Rhodesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984389"}
{"pmid": "20984390", "title": "Incubation of tsetse pupae: increased transmission-rate of Trypanosoma rhodesiense in Glossina morsitans.", "content": "Incubation of tsetse pupae: increased transmission-rate of Trypanosoma rhodesiense in Glossina morsitans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984390"}
{"pmid": "20984391", "title": "The serum albumin and globulin levels in Africans as compared with Europeans; with a note on technique.", "content": "The serum albumin and globulin levels in Africans as compared with Europeans; with a note on technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984391"}
{"pmid": "20984392", "title": "Taxonomy of the Ethiopian sandflies (Phlebotomus); classification and synonymy.", "content": "Taxonomy of the Ethiopian sandflies (Phlebotomus); classification and synonymy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984392"}
{"pmid": "20984393", "title": "The use of avian malaria for the discovery of drugs effective in the treatment and prevention of human malaria; drugs for clinical treatment and clinical prophylaxis.", "content": "The use of avian malaria for the discovery of drugs effective in the treatment and prevention of human malaria; drugs for clinical treatment and clinical prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984393"}
{"pmid": "20984394", "title": "The sex ratio of infected flies found in transmission-experiments with Glossina morsitans and Trypanosoma rhodesiense.", "content": "The sex ratio of infected flies found in transmission-experiments with Glossina morsitans and Trypanosoma rhodesiense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984394"}
{"pmid": "20984395", "title": "EFFECTS of mepacrine on the gastrointestinal tract of man.", "content": "EFFECTS of mepacrine on the gastrointestinal tract of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984395"}
{"pmid": "20984396", "title": "The action in vitro of diamidines and other compounds on Leishmania donovani.", "content": "The action in vitro of diamidines and other compounds on Leishmania donovani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984396"}
{"pmid": "20984397", "title": "Studies on synthetic antimalarial drugs; hydrolytic determination of paludrine.", "content": "Studies on synthetic antimalarial drugs; hydrolytic determination of paludrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984397"}
{"pmid": "20984398", "title": "A technique for obtaining bacteria-free suspensions of sporozoites from the salivary glands of infected mosquitoes.", "content": "A technique for obtaining bacteria-free suspensions of sporozoites from the salivary glands of infected mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984398"}
{"pmid": "20984406", "title": "Immunization with the vole bacillus; the protective value of the vole bacillus (Wells) as compared with BCG against tuberculous infection.", "content": "Immunization with the vole bacillus; the protective value of the vole bacillus (Wells) as compared with BCG against tuberculous infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984406"}
{"pmid": "20984407", "title": "Vole bacillus; susceptibility of South African wild rodents to the vole strain of acid-fast bacillus and to other acid-fast bacilli; preliminary report.", "content": "Vole bacillus; susceptibility of South African wild rodents to the vole strain of acid-fast bacillus and to other acid-fast bacilli; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984407"}
{"pmid": "20984408", "title": "Pulmonary acariasis; its relationship to the eosinophil lung and Löffler's syndrome.", "content": "Pulmonary acariasis; its relationship to the eosinophil lung and Löffler's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984408"}
{"pmid": "20984401", "title": "The diamidines; their pharmacological actions and their therapeutic uses in some tropical diseases.", "content": "The diamidines; their pharmacological actions and their therapeutic uses in some tropical diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984401"}
{"pmid": "20984410", "title": "Photoroentgenographic results; a comparison of the 4 x 5'' and the 70mm. equipment in 1,713 cases.", "content": "Photoroentgenographic results; a comparison of the 4 x 5'' and the 70mm. equipment in 1,713 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984410"}
{"pmid": "20984409", "title": "Ambulatory pneumothorax induction; a report of one year's experience in Chungking.", "content": "Ambulatory pneumothorax induction; a report of one year's experience in Chungking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984409"}
{"pmid": "20984411", "title": "Cutaneous reinfection in pulmonary tuberculosis.", "content": "Cutaneous reinfection in pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984411"}
{"pmid": "20984400", "title": "Tick-borne relapsing fever in East Africa.", "content": "Tick-borne relapsing fever in East Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984400"}
{"pmid": "20984412", "title": "The sulphones in clinical tuberculosis.", "content": "The sulphones in clinical tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984412"}
{"pmid": "20984413", "title": "Virulence of tubercle bacilli; in vitro testing by the use of diphtheria antitoxin.", "content": "Virulence of tubercle bacilli; in vitro testing by the use of diphtheria antitoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984413"}
{"pmid": "20984399", "title": "Intradermal test in malaria.", "content": "Intradermal test in malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984399"}
{"pmid": "20984414", "title": "Periodicals devoted to tuberculosis in the United States of America.", "content": "Periodicals devoted to tuberculosis in the United States of America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984414"}
{"pmid": "20984436", "title": "Transplantation into the bowel of duplicated ureters, with a report on three cases.", "content": "Transplantation into the bowel of duplicated ureters, with a report on three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984436"}
{"pmid": "20984438", "title": "Some observations on the incidence of 665 personal cases of urinary lithiasis.", "content": "Some observations on the incidence of 665 personal cases of urinary lithiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984438"}
{"pmid": "20984437", "title": "Some uses for free muscle grafts in urology.", "content": "Some uses for free muscle grafts in urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984437"}
{"pmid": "20984439", "title": "An operation for varicocele.", "content": "An operation for varicocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984439"}
{"pmid": "20984440", "title": "The anterior epididymis.", "content": "The anterior epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984440"}
{"pmid": "20984441", "title": "An improved lithotrite.", "content": "An improved lithotrite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984441"}
{"pmid": "20984442", "title": "A tumour of the renal capsule; case report.", "content": "A tumour of the renal capsule; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984442"}
{"pmid": "20984443", "title": "A large stone removed from the prostatic region; case report.", "content": "A large stone removed from the prostatic region; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984443"}
{"pmid": "20984433", "title": "The fight against tuberculosis in Italy in the war.", "content": "The fight against tuberculosis in Italy in the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984433"}
{"pmid": "20984435", "title": "The significance of haemoptysis.", "content": "The significance of haemoptysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984435"}
{"pmid": "20984444", "title": "Retropubic prostatectomy.", "content": "Retropubic prostatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984444"}
{"pmid": "20984445", "title": "Prostatic surgery, in the University of Michigan Hospital in 1945.", "content": "Prostatic surgery, in the University of Michigan Hospital in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984445"}
{"pmid": "20984434", "title": "Combined pulmonary and extra-pulmonary tuberculosis, with special reference to the prognosis in skeletal disease.", "content": "Combined pulmonary and extra-pulmonary tuberculosis, with special reference to the prognosis in skeletal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984434"}
{"pmid": "20984446", "title": "The use of thrombin in the control of post-prostatic resection blood loss.", "content": "The use of thrombin in the control of post-prostatic resection blood loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984446"}
{"pmid": "20984447", "title": "A case of paranephric cyst.", "content": "A case of paranephric cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984447"}
{"pmid": "20984448", "title": "\"Wired for electricity\" or the case of a bizarre foreign body in the bladder.", "content": "\"Wired for electricity\" or the case of a bizarre foreign body in the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984448"}
{"pmid": "20984449", "title": "Neurofibromatosis involving the left labium majus of a colored patient.", "content": "Neurofibromatosis involving the left labium majus of a colored patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984449"}
{"pmid": "20984451", "title": "The vaginal interposition operation and its modifications for urological conditions.", "content": "The vaginal interposition operation and its modifications for urological conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984451"}
{"pmid": "20984450", "title": "In vitro susceptibility to penicillin of bacteria in chronic prostatitis.", "content": "In vitro susceptibility to penicillin of bacteria in chronic prostatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984450"}
{"pmid": "20984452", "title": "Syphilis and the Wassermann reaction.", "content": "Syphilis and the Wassermann reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984452"}
{"pmid": "20984453", "title": "The in-patient syphilis department of the hospital as a prophylactic measure.", "content": "The in-patient syphilis department of the hospital as a prophylactic measure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984453"}
{"pmid": "20984454", "title": "Penicillin sensitivity and morphology of the Reiter strain of Treponema pallidum after cultivation in media containing penicillin.", "content": "Penicillin sensitivity and morphology of the Reiter strain of Treponema pallidum after cultivation in media containing penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984454"}
{"pmid": "20984455", "title": "Penicillin treatment of benign late gummatous syphilis; a report of twenty-one cases.", "content": "Penicillin treatment of benign late gummatous syphilis; a report of twenty-one cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984455"}
{"pmid": "20984456", "title": "Acute syphilitic meningitis treated with penicillin; a progress report.", "content": "Acute syphilitic meningitis treated with penicillin; a progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984456"}
{"pmid": "20984457", "title": "Syphilitic arachnoiditis treated with penicillin.", "content": "Syphilitic arachnoiditis treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984457"}
{"pmid": "20984458", "title": "Intrathecal administration of penicillin in general paresis.", "content": "Intrathecal administration of penicillin in general paresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984458"}
{"pmid": "20984459", "title": "The toxicologic and therapeutic action of penicillin on mice infected with the agent of lymphogranuloma venereum.", "content": "The toxicologic and therapeutic action of penicillin on mice infected with the agent of lymphogranuloma venereum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984459"}
{"pmid": "20984460", "title": "Penicillin treatment of previously untreated acute gonorrhea.", "content": "Penicillin treatment of previously untreated acute gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984460"}
{"pmid": "20984461", "title": "The incidence of positive serologic reactions in multiple blood donors.", "content": "The incidence of positive serologic reactions in multiple blood donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984461"}
{"pmid": "20984463", "title": "Lumbar puncture headache; a statistical analysis of five hundred punctures.", "content": "Lumbar puncture headache; a statistical analysis of five hundred punctures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984463"}
{"pmid": "20984462", "title": "False positive serologic tests for syphilis following blood donation.", "content": "False positive serologic tests for syphilis following blood donation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984462"}
{"pmid": "20984464", "title": "A study of liver function following massive arsenotherapy for syphilis.", "content": "A study of liver function following massive arsenotherapy for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984464"}
{"pmid": "20984465", "title": "The clinical and laboratory differentiation between chancroid and lymphogranuloma venereum.", "content": "The clinical and laboratory differentiation between chancroid and lymphogranuloma venereum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984465"}
{"pmid": "20984466", "title": "Follow-up service for private physician cases of venereal disease in Hawaii.", "content": "Follow-up service for private physician cases of venereal disease in Hawaii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984466"}
{"pmid": "20984481", "title": "[Current problems in virusology].", "content": "[Current problems in virusology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984481"}
{"pmid": "20984482", "title": "[Agglutination reaction of bacteria loaded with virus as a method for detection of viruses and antibodies in vitro].", "content": "[Agglutination reaction of bacteria loaded with virus as a method for detection of viruses and antibodies in vitro].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984482"}
{"pmid": "20984483", "title": "[Experimental data for use of Hurst's reaction in laboratory practice].", "content": "[Experimental data for use of Hurst's reaction in laboratory practice].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984483"}
{"pmid": "20984484", "title": "[Quick diagnosis of influenza by detection of the antigen in the nasopharyngeal smear].", "content": "[Quick diagnosis of influenza by detection of the antigen in the nasopharyngeal smear].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984484"}
{"pmid": "20984485", "title": "[Dynamics of influenza antibodies of A and B types in the adult population].", "content": "[Dynamics of influenza antibodies of A and B types in the adult population].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984485"}
{"pmid": "20984486", "title": "[Changes of the virus neutralizing properties of the nasal secretion in the process of immunization].", "content": "[Changes of the virus neutralizing properties of the nasal secretion in the process of immunization].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984486"}
{"pmid": "20984487", "title": "[Character of the influenza epidemic of the end of 1943].", "content": "[Character of the influenza epidemic of the end of 1943].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984487"}
{"pmid": "20984488", "title": "[On the nature of malignant tumors].", "content": "[On the nature of malignant tumors].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984488"}
{"pmid": "20984489", "title": "[Biological Frei test in the study of the inguinal granulomatoses].", "content": "[Biological Frei test in the study of the inguinal granulomatoses].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984489"}
{"pmid": "20984490", "title": "[Toxic properties of the virus of variola vaccine and the Duran-Reynolds factor].", "content": "[Toxic properties of the virus of variola vaccine and the Duran-Reynolds factor].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984490"}
{"pmid": "20984491", "title": "[Pathogenesis of alimentary (toxic) aleukia].", "content": "[Pathogenesis of alimentary (toxic) aleukia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984491"}
{"pmid": "20984492", "title": "[Modification of the method of agglutinin adsorption].", "content": "[Modification of the method of agglutinin adsorption].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984492"}
{"pmid": "20984493", "title": "[Concentration of bovine antitetanus antitoxic serum from the ballast proteins].", "content": "[Concentration of bovine antitetanus antitoxic serum from the ballast proteins].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984493"}
{"pmid": "20984494", "title": "[Experimental eradication of tularemia in a region near the front].", "content": "[Experimental eradication of tularemia in a region near the front].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984494"}
{"pmid": "20984495", "title": "[Work of the institutes of epidemiology and microbiology].", "content": "[Work of the institutes of epidemiology and microbiology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984495"}
{"pmid": "20984496", "title": "[Pamiati I.I. Mechnikov].", "content": "[Pamiati I.I. Mechnikov].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984496"}
{"pmid": "20984497", "title": "[Cytology and kariology of bacteria of the intestinal-typhoid group].", "content": "[Cytology and kariology of bacteria of the intestinal-typhoid group].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984497"}
{"pmid": "20984498", "title": "[On the nature of malignant tumors].", "content": "[On the nature of malignant tumors].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984498"}
{"pmid": "20984499", "title": "[Chemistry and biochemistry of the lipoid antigens; examination of the chemical nature of the \"true Wassermann substance\"].", "content": "[Chemistry and biochemistry of the lipoid antigens; examination of the chemical nature of the \"true Wassermann substance\"].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984499"}
{"pmid": "20984501", "title": "[Immunology of plague; theoretical principles of the pathology and immunology of plague].", "content": "[Immunology of plague; theoretical principles of the pathology and immunology of plague].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984501"}
{"pmid": "20984500", "title": "[Chemistry and biochemistry of the lipoid antigens; examination of the immunobiological properties of the \"true Wassermann substance\"].", "content": "[Chemistry and biochemistry of the lipoid antigens; examination of the immunobiological properties of the \"true Wassermann substance\"].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984500"}
{"pmid": "20984502", "title": "[Role of the tissular barriers in immunity; effect of influenza on the permeability of pulmonary tissue].", "content": "[Role of the tissular barriers in immunity; effect of influenza on the permeability of pulmonary tissue].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984502"}
{"pmid": "20984503", "title": "[Mechanism of natural and acquired immunity to influenza; on the possibility of the reactivation of influenza virus after its mixture with immune serum].", "content": "[Mechanism of natural and acquired immunity to influenza; on the possibility of the reactivation of influenza virus after its mixture with immune serum].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984503"}
{"pmid": "20984504", "title": "[Mechanism of natural and acquired immunity to influenza; quantitative reactivation of the virus of influenza from neutral mixtures in relation to the concentration of antibodies, the temperature and the length of contact].", "content": "[Mechanism of natural and acquired immunity to influenza; quantitative reactivation of the virus of influenza from neutral mixtures in relation to the concentration of antibodies, the temperature and the length of contact].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984504"}
{"pmid": "20984505", "title": "[Effect of anaphylactic shock on both the infectious process and intoxication].", "content": "[Effect of anaphylactic shock on both the infectious process and intoxication].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984505"}
{"pmid": "20984506", "title": "[Method of concentration and detection of hapten].", "content": "[Method of concentration and detection of hapten].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984506"}
{"pmid": "20984507", "title": "[Results of mass investigations of bacilli-carrying].", "content": "[Results of mass investigations of bacilli-carrying].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984507"}
{"pmid": "20984508", "title": "[Specificity of the agglutination reaction in dysentery].", "content": "[Specificity of the agglutination reaction in dysentery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984508"}
{"pmid": "20984509", "title": "[Immunizing properties of the nucleoprotein of the cholera vibrio].", "content": "[Immunizing properties of the nucleoprotein of the cholera vibrio].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984509"}
{"pmid": "20984510", "title": "[A combined choleraic antiphage and agglutinating serum].", "content": "[A combined choleraic antiphage and agglutinating serum].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984510"}
{"pmid": "20984511", "title": "[Problem of inguinal lymphagranulomatosis (Nicolas-Favre)].", "content": "[Problem of inguinal lymphagranulomatosis (Nicolas-Favre)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984511"}
{"pmid": "20984512", "title": "[Determination of the titer of reaction in copro-agglutination in dysentery].", "content": "[Determination of the titer of reaction in copro-agglutination in dysentery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984512"}
{"pmid": "20984513", "title": "[Some data concerning the phagotherapy of dysentery and typhoid].", "content": "[Some data concerning the phagotherapy of dysentery and typhoid].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984513"}
{"pmid": "20984514", "title": "[Bacteriological diagnosis of intestinal infections; nutritive media for obtaining hemocultures in typhoid].", "content": "[Bacteriological diagnosis of intestinal infections; nutritive media for obtaining hemocultures in typhoid].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984514"}
{"pmid": "20984515", "title": "[Relation between the antigenic structure of hemocultures and severity of the illness in typhoid].", "content": "[Relation between the antigenic structure of hemocultures and severity of the illness in typhoid].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984515"}
{"pmid": "20984516", "title": "[Atypical typhoid].", "content": "[Atypical typhoid].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984516"}
{"pmid": "20984517", "title": "[Fly-epidemic typhoid].", "content": "[Fly-epidemic typhoid].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984517"}
{"pmid": "20984518", "title": "[Water-epidemic typhoid].", "content": "[Water-epidemic typhoid].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984518"}
{"pmid": "20984519", "title": "[Conservant materials for pathogenic bacteria of the intestinal-typhoid group].", "content": "[Conservant materials for pathogenic bacteria of the intestinal-typhoid group].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984519"}
{"pmid": "20984520", "title": "[Bacteriological diagnosis of intestinal infections; a new variety of B. paratyphi A].", "content": "[Bacteriological diagnosis of intestinal infections; a new variety of B. paratyphi A].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984520"}
{"pmid": "20984521", "title": "[Etiology of dysentery].", "content": "[Etiology of dysentery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984521"}
{"pmid": "20984522", "title": "[Biological characteristics of B dysenteriae ambiguum and its etiological role in dysentery].", "content": "[Biological characteristics of B dysenteriae ambiguum and its etiological role in dysentery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984522"}
{"pmid": "20984523", "title": "[Precipitation reaction in dysentery].", "content": "[Precipitation reaction in dysentery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984523"}
{"pmid": "20984524", "title": "[Description of a closed outbreak of dysentery in a train].", "content": "[Description of a closed outbreak of dysentery in a train].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984524"}
{"pmid": "20984525", "title": "[On the duration of bacilli-carrying in children who have recovered from dysentery].", "content": "[On the duration of bacilli-carrying in children who have recovered from dysentery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984525"}
{"pmid": "20984526", "title": "[Coliprophylaxis of dysentery].", "content": "[Coliprophylaxis of dysentery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984526"}
{"pmid": "20984527", "title": "[Prophylaxis of dysentery by the method of continuous phagization].", "content": "[Prophylaxis of dysentery by the method of continuous phagization].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984527"}
{"pmid": "20984528", "title": "[Action of sulfidine on the dysentery bacteriophage and its lytic properties].", "content": "[Action of sulfidine on the dysentery bacteriophage and its lytic properties].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984528"}
{"pmid": "20984529", "title": "[Epidemiology of hemorrhagic nephroso-nephritis].", "content": "[Epidemiology of hemorrhagic nephroso-nephritis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984529"}
{"pmid": "20984530", "title": "[Experimental study of vaccination with S- and R-varieties of BCG of the bovine strain].", "content": "[Experimental study of vaccination with S- and R-varieties of BCG of the bovine strain].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984530"}
{"pmid": "20984531", "title": "[Immunogenic properties of dry BCG vaccine].", "content": "[Immunogenic properties of dry BCG vaccine].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984531"}
{"pmid": "20984532", "title": "[Etiology of angina septica (alimentary toxic aleukia) and measures for its prevention].", "content": "[Etiology of angina septica (alimentary toxic aleukia) and measures for its prevention].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984532"}
{"pmid": "20984533", "title": "IVAN Dmitrievich Ionin (nekrolog).", "content": "IVAN Dmitrievich Ionin (nekrolog).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984533"}
{"pmid": "20984534", "title": "[Role of clinico-bacteriological and clinico-immunological parallels in wound infection].", "content": "[Role of clinico-bacteriological and clinico-immunological parallels in wound infection].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984534"}
{"pmid": "20984535", "title": "[Bacterial flora of the cerebrospinal fluid in gunshot wounds of the cranium].", "content": "[Bacterial flora of the cerebrospinal fluid in gunshot wounds of the cranium].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984535"}
{"pmid": "20984536", "title": "[Anaerobic bacteria of wounds in hospitals of the far rear].", "content": "[Anaerobic bacteria of wounds in hospitals of the far rear].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984536"}
{"pmid": "20984537", "title": "[Toxin formation in B. perfringens].", "content": "[Toxin formation in B. perfringens].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984537"}
{"pmid": "20984538", "title": "[Specific prophylaxis and treatment of gas gangrene in experiment].", "content": "[Specific prophylaxis and treatment of gas gangrene in experiment].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984538"}
{"pmid": "20984539", "title": "[Experimental quick obtention of antigangrene sera].", "content": "[Experimental quick obtention of antigangrene sera].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984539"}
{"pmid": "20984540", "title": "[Comparative evaluation of the medicinal and prophylactic properties of the antitetanic and antigangrenous sera obtained from cattle and horses].", "content": "[Comparative evaluation of the medicinal and prophylactic properties of the antitetanic and antigangrenous sera obtained from cattle and horses].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984540"}
{"pmid": "20984541", "title": "[Types of epidemic outbreaks of tularemia].", "content": "[Types of epidemic outbreaks of tularemia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984541"}
{"pmid": "20984542", "title": "[Ring precipitation as a method of acceleration of diagnosis of tularemia in small rodents].", "content": "[Ring precipitation as a method of acceleration of diagnosis of tularemia in small rodents].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984542"}
{"pmid": "20984543", "title": "[Comparative evaluation of subcutaneous testing with tularin, of intracutaneous testing, and of the agglutination reaction in tularemia].", "content": "[Comparative evaluation of subcutaneous testing with tularin, of intracutaneous testing, and of the agglutination reaction in tularemia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984543"}
{"pmid": "20984544", "title": "[An accelerated serological diagnosis of tularemia and typhus under field conditions].", "content": "[An accelerated serological diagnosis of tularemia and typhus under field conditions].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984544"}
{"pmid": "20984545", "title": "[A water epidemic of tularemia].", "content": "[A water epidemic of tularemia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984545"}
{"pmid": "20984546", "title": "[Study of the bactericidal action of chlorine on B. tularense in drinking water].", "content": "[Study of the bactericidal action of chlorine on B. tularense in drinking water].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984546"}
{"pmid": "20984547", "title": "[On the mechanic of infection and immunity in experimental tularemia].", "content": "[On the mechanic of infection and immunity in experimental tularemia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984547"}
{"pmid": "20984548", "title": "[On the role of the field mouse Apodemus agrarius) in the epizootology and epidemiology of tularemia].", "content": "[On the role of the field mouse Apodemus agrarius) in the epizootology and epidemiology of tularemia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984548"}
{"pmid": "20984549", "title": "[Experimental vaccination of man against brucellosis].", "content": "[Experimental vaccination of man against brucellosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984549"}
{"pmid": "20984550", "title": "[Chemotherapy of brucellosis].", "content": "[Chemotherapy of brucellosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984550"}
{"pmid": "20984551", "title": "[The physical condition of the child as factor in producing and maintaining immunity in diphtheria].", "content": "[The physical condition of the child as factor in producing and maintaining immunity in diphtheria].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984551"}
{"pmid": "20984552", "title": "Some features of the spread of plant diseases by air-borne and insect-borne inoculum.", "content": "Some features of the spread of plant diseases by air-borne and insect-borne inoculum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984552"}
{"pmid": "20984553", "title": "Seed and seedling infection of barley, bromegrass, and wheat by Xanthomonas translucens var. cerealis.", "content": "Seed and seedling infection of barley, bromegrass, and wheat by Xanthomonas translucens var. cerealis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984553"}
{"pmid": "20984554", "title": "Occurrence of curly-top virus in meristematic tissue.", "content": "Occurrence of curly-top virus in meristematic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984554"}
{"pmid": "20984555", "title": "Seasonal changes in biological equilibria involving two chondriosomal systems in variegated Hosta.", "content": "Seasonal changes in biological equilibria involving two chondriosomal systems in variegated Hosta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984555"}
{"pmid": "20984556", "title": "Antidotal action of metrazol against pentothal sodium overdose.", "content": "Antidotal action of metrazol against pentothal sodium overdose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984556"}
{"pmid": "20984557", "title": "Cholinergic action of the anti-sympathetic agent priscol (benzylimidazoline HCl).", "content": "Cholinergic action of the anti-sympathetic agent priscol (benzylimidazoline HCl).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984557"}
{"pmid": "20984558", "title": "Pamaquin; occurrence of leucopenia.", "content": "Pamaquin; occurrence of leucopenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984558"}
{"pmid": "20984559", "title": "Spinal fluid in the retrospective diagnosis of sub-clinical poliomyelitis.", "content": "Spinal fluid in the retrospective diagnosis of sub-clinical poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984559"}
{"pmid": "20984560", "title": "The existence of variations in the ease with which thrombin preparations may be inactivated by antithrombin.", "content": "The existence of variations in the ease with which thrombin preparations may be inactivated by antithrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984560"}
{"pmid": "20984561", "title": "Studies on the rate and completeness with which intravenously injected radioactive iron is utilized.", "content": "Studies on the rate and completeness with which intravenously injected radioactive iron is utilized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984561"}
{"pmid": "20984562", "title": "Osteosarcoma from intravenous beryllium compounds in rabbits.", "content": "Osteosarcoma from intravenous beryllium compounds in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984562"}
{"pmid": "20984563", "title": "Studies on pyridoxine deficiency in rhesus monkeys.", "content": "Studies on pyridoxine deficiency in rhesus monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984563"}
{"pmid": "20984564", "title": "Effect of biotin and other B vitamins on proteinases.", "content": "Effect of biotin and other B vitamins on proteinases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984564"}
{"pmid": "20984565", "title": "Experimental jugular phlebitis.", "content": "Experimental jugular phlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984565"}
{"pmid": "20984566", "title": "The pathogenesis and pathology of experimental aid-borne influenza A virus infection in mice.", "content": "The pathogenesis and pathology of experimental aid-borne influenza A virus infection in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984566"}
{"pmid": "20984567", "title": "Ischemic and anoxemic damage to myocardial capillaries and its relation to shock, angina pectoris and myocardial infarction.", "content": "Ischemic and anoxemic damage to myocardial capillaries and its relation to shock, angina pectoris and myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984567"}
{"pmid": "20984568", "title": "The significance of hyperemia around tumor implants.", "content": "The significance of hyperemia around tumor implants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984568"}
{"pmid": "20984569", "title": "Caloric intake and the utilization of dietary protein for growth.", "content": "Caloric intake and the utilization of dietary protein for growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984569"}
{"pmid": "20984570", "title": "Relationship between protein intake and pyridoxine deficiency in the rat; effect of supplementing a low-protein diet with methionine.", "content": "Relationship between protein intake and pyridoxine deficiency in the rat; effect of supplementing a low-protein diet with methionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984570"}
{"pmid": "20984571", "title": "Relationship between salt intake and sweat salt concentration under conditions of hard work in humid heat.", "content": "Relationship between salt intake and sweat salt concentration under conditions of hard work in humid heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984571"}
{"pmid": "20984572", "title": "An unidentified factor or factors effective in the treatment of experimental blood dyscrasias in rats.", "content": "An unidentified factor or factors effective in the treatment of experimental blood dyscrasias in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984572"}
{"pmid": "20984573", "title": "Problems of world nutrition.", "content": "Problems of world nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984573"}
{"pmid": "20984574", "title": "The failure of skeletal calcification produced by high lactose diets and by simple caloric restriction.", "content": "The failure of skeletal calcification produced by high lactose diets and by simple caloric restriction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984574"}
{"pmid": "20984576", "title": "Further observations on choline and related compounds in nutrition.", "content": "Further observations on choline and related compounds in nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984576"}
{"pmid": "20984575", "title": "Hand sweat values in the calculation of chloride and nitrogen balance under conditions of hard work in humid heat.", "content": "Hand sweat values in the calculation of chloride and nitrogen balance under conditions of hard work in humid heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984575"}
{"pmid": "20984577", "title": "Growing a diet deficient in certain elements by hydroponics.", "content": "Growing a diet deficient in certain elements by hydroponics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984577"}
{"pmid": "20984578", "title": "Riboflavin excretions and test dose returns of young women during periods of positive and negative nitrogen balances.", "content": "Riboflavin excretions and test dose returns of young women during periods of positive and negative nitrogen balances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984578"}
{"pmid": "20984580", "title": "Nutrition survey in Puerto Rico.", "content": "Nutrition survey in Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984580"}
{"pmid": "20984579", "title": "Availability to human subjects of riboflavin from yeasts.", "content": "Availability to human subjects of riboflavin from yeasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984579"}
{"pmid": "20984581", "title": "The effects of copper on liver tumor induction by p-dimethylaminoazobenzene.", "content": "The effects of copper on liver tumor induction by p-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984581"}
{"pmid": "20984582", "title": "Nutritional improvement of cereal flours and cereal grains; influence on growth and efficiency of protein utilization of additions of small amounts of dried culture yeast (strain G) to the proteins in enriched white flour and table corn meal.", "content": "Nutritional improvement of cereal flours and cereal grains; influence on growth and efficiency of protein utilization of additions of small amounts of dried culture yeast (strain G) to the proteins in enriched white flour and table corn meal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984582"}
{"pmid": "20984583", "title": "Nutritional improvement of cereal flours and cereal grains; influence on growth and protein utilization of additions of small amounts of dried cultured yeast (strain G) to the proteins in polished rice.", "content": "Nutritional improvement of cereal flours and cereal grains; influence on growth and protein utilization of additions of small amounts of dried cultured yeast (strain G) to the proteins in polished rice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984583"}
{"pmid": "20984584", "title": "The provitamin A requirement of laying hens.", "content": "The provitamin A requirement of laying hens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984584"}
{"pmid": "20984585", "title": "Pamaquine naphthoate as a prophylactic for malarial infections.", "content": "Pamaquine naphthoate as a prophylactic for malarial infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984585"}
{"pmid": "20984586", "title": "The characters of the rabbit papilloma virus.", "content": "The characters of the rabbit papilloma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984586"}
{"pmid": "20984587", "title": "Serum albumine as a protective rather than nutritive growth factor in bacteriological media.", "content": "Serum albumine as a protective rather than nutritive growth factor in bacteriological media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984587"}
{"pmid": "20984588", "title": "Action of chemotherapeutic agents on the organism of granuloma inguinale.", "content": "Action of chemotherapeutic agents on the organism of granuloma inguinale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984588"}
{"pmid": "20984589", "title": "The role of selection in antigenic variation of blood parasites.", "content": "The role of selection in antigenic variation of blood parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984589"}
{"pmid": "20984590", "title": "The role of latent pneumontropic viruses in acute respiratory disease.", "content": "The role of latent pneumontropic viruses in acute respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984590"}
{"pmid": "20984591", "title": "Coexistence of two antibodies for crystalline insulin in human serum.", "content": "Coexistence of two antibodies for crystalline insulin in human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984591"}
{"pmid": "20984592", "title": "The enhancement and properties of the complement-fixing antigens of lymphogranuloma venereum.", "content": "The enhancement and properties of the complement-fixing antigens of lymphogranuloma venereum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984592"}
{"pmid": "20984593", "title": "Penicillin sensitivity of staphylococcus; in vitro tests.", "content": "Penicillin sensitivity of staphylococcus; in vitro tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984593"}
{"pmid": "20984595", "title": "Chemotherapeutic effect of nitroakridin and rutenol in rickettsial infections in eggs and mice.", "content": "Chemotherapeutic effect of nitroakridin and rutenol in rickettsial infections in eggs and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984595"}
{"pmid": "20984594", "title": "The activity of some antibiotics and sulfonamides in vitro and in vivo upon the agents of lymphogranuloma venereum and feline pneumonitis.", "content": "The activity of some antibiotics and sulfonamides in vitro and in vivo upon the agents of lymphogranuloma venereum and feline pneumonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984594"}
{"pmid": "20984596", "title": "The detoxification by acetylation of soluble antigens from Shigella dysenteriae and E. typhosa.", "content": "The detoxification by acetylation of soluble antigens from Shigella dysenteriae and E. typhosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984596"}
{"pmid": "20984597", "title": "Effect of various routes of administration of penicillin upon experimental lobar pneumonia in rats.", "content": "Effect of various routes of administration of penicillin upon experimental lobar pneumonia in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984597"}
{"pmid": "20984598", "title": "Anatomy and physiology of diarthrodial joints.", "content": "Anatomy and physiology of diarthrodial joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984598"}
{"pmid": "20984599", "title": "Bacteriological investigation of air during an epidemic of haemolytic streptococcal throat infection.", "content": "Bacteriological investigation of air during an epidemic of haemolytic streptococcal throat infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984599"}
{"pmid": "20984600", "title": "Ankylosing spondylitis; its aetiology and pathology.", "content": "Ankylosing spondylitis; its aetiology and pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984600"}
{"pmid": "20984601", "title": "Orthopaedic aspects of rheumatoid arthritis.", "content": "Orthopaedic aspects of rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984601"}
{"pmid": "20984602", "title": "Return to normal of x-ray changes in rheumatoid arthritis; case report.", "content": "Return to normal of x-ray changes in rheumatoid arthritis; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984602"}
{"pmid": "20984603", "title": "Rheumatoid arthritis.", "content": "Rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984603"}
{"pmid": "20984609", "title": "The broken mandibular needle.", "content": "The broken mandibular needle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984609"}
{"pmid": "20984610", "title": "Verification of results on the use of sulfonamides in pulpitis.", "content": "Verification of results on the use of sulfonamides in pulpitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984610"}
{"pmid": "20984611", "title": "The newer knowledge of hygiene in diet.", "content": "The newer knowledge of hygiene in diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984611"}
{"pmid": "20984612", "title": "Impacted and aberrant teeth; their history, causes and treatment.", "content": "Impacted and aberrant teeth; their history, causes and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984612"}
{"pmid": "20984613", "title": "The diagnosis and the planning of treatment in cleft palate cases.", "content": "The diagnosis and the planning of treatment in cleft palate cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984613"}
{"pmid": "20984614", "title": "The plastics; with special emphasis on the use of acrylics in the construction of jacket crowns, bridgework and partial dentures.", "content": "The plastics; with special emphasis on the use of acrylics in the construction of jacket crowns, bridgework and partial dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984614"}
{"pmid": "20984615", "title": "Brain abscesses and oral surgery.", "content": "Brain abscesses and oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984615"}
{"pmid": "20984616", "title": "Diagnostic oral roentgenology.", "content": "Diagnostic oral roentgenology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984616"}
{"pmid": "20984617", "title": "The experiences of a dental prisoner of war in Thailand camps.", "content": "The experiences of a dental prisoner of war in Thailand camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984617"}
{"pmid": "20984618", "title": "A note on the electron microscope.", "content": "A note on the electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984618"}
{"pmid": "20984619", "title": "Penicillin in dental surgery.", "content": "Penicillin in dental surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984619"}
{"pmid": "20984623", "title": "Discussion of legal problems.", "content": "Discussion of legal problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984623"}
{"pmid": "20984624", "title": "Scientific endodontia.", "content": "Scientific endodontia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984624"}
{"pmid": "20984626", "title": "Cooperation.", "content": "Cooperation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984626"}
{"pmid": "20984627", "title": "What constitutes an adequate requirement in pre-clinical operative dentistry.", "content": "What constitutes an adequate requirement in pre-clinical operative dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984627"}
{"pmid": "20984628", "title": "Will orthodontics become a part of contemplated Government health programs for children.", "content": "Will orthodontics become a part of contemplated Government health programs for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984628"}
{"pmid": "20984629", "title": "Will orthodontics become a part of contemplated Government health programs for children.", "content": "Will orthodontics become a part of contemplated Government health programs for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984629"}
{"pmid": "20984630", "title": "Will orthodontics become a part of contemplated Government health programs for children.", "content": "Will orthodontics become a part of contemplated Government health programs for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984630"}
{"pmid": "20984631", "title": "Standardization of the three-quarter crown preparation.", "content": "Standardization of the three-quarter crown preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984631"}
{"pmid": "20984632", "title": "The oral mucosa.", "content": "The oral mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984632"}
{"pmid": "20984633", "title": "Wholemeal versus white bread.", "content": "Wholemeal versus white bread.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984633"}
{"pmid": "20984634", "title": "The influence of some recent developments on the practice of conservative dentistry.", "content": "The influence of some recent developments on the practice of conservative dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984634"}
{"pmid": "20984635", "title": "Metal dies for technical instruction.", "content": "Metal dies for technical instruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984635"}
{"pmid": "20984636", "title": "Experimental methods used in the investing of wax patterns to compensate for shrinkage of metal on casting.", "content": "Experimental methods used in the investing of wax patterns to compensate for shrinkage of metal on casting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984636"}
{"pmid": "20984657", "title": "Vaginal and cervical cytology in uterine cancer diagnosis.", "content": "Vaginal and cervical cytology in uterine cancer diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984657"}
{"pmid": "20984659", "title": "Gestational neuronitis.", "content": "Gestational neuronitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984659"}
{"pmid": "20984658", "title": "Carcinoma of the cervix after supravaginal hysterectomy.", "content": "Carcinoma of the cervix after supravaginal hysterectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984658"}
{"pmid": "20984660", "title": "Spinal anesthesia in vaginal delivery; a report of 1,547 cases.", "content": "Spinal anesthesia in vaginal delivery; a report of 1,547 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984660"}
{"pmid": "20984661", "title": "Future prospects for obstetric care in the United States.", "content": "Future prospects for obstetric care in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984661"}
{"pmid": "20984662", "title": "A blood bank for a lying-in hospital.", "content": "A blood bank for a lying-in hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984662"}
{"pmid": "20984663", "title": "Some contributions of endocrinology to obstetrics and gynecology.", "content": "Some contributions of endocrinology to obstetrics and gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984663"}
{"pmid": "20984664", "title": "Hysterectomy; therapeutic necessity or surgical racket?", "content": "Hysterectomy; therapeutic necessity or surgical racket?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984664"}
{"pmid": "20984665", "title": "The significance of myoma uteri in pregnancy.", "content": "The significance of myoma uteri in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984665"}
{"pmid": "20984666", "title": "Luteoma of the ovary; a case showing decidualization of the endometrium and a high pregnanediol excretion rate.", "content": "Luteoma of the ovary; a case showing decidualization of the endometrium and a high pregnanediol excretion rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984666"}
{"pmid": "20984667", "title": "Lymphangiocystic fibroma of uterus.", "content": "Lymphangiocystic fibroma of uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984667"}
{"pmid": "20984668", "title": "Experiences with the labor procedure of Grantly Dick Read.", "content": "Experiences with the labor procedure of Grantly Dick Read.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984668"}
{"pmid": "20984669", "title": "The induction of labor with methergine; preliminary report.", "content": "The induction of labor with methergine; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984669"}
{"pmid": "20984670", "title": "Difficulties and accidents encountered in construction of the vagina.", "content": "Difficulties and accidents encountered in construction of the vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984670"}
{"pmid": "20984671", "title": "The duration of gestation; with special reference to the calculation of the date of delivery from basal temperature graphs.", "content": "The duration of gestation; with special reference to the calculation of the date of delivery from basal temperature graphs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984671"}
{"pmid": "20984672", "title": "A ten-year survey of cesarean section at the New Haven Hospital.", "content": "A ten-year survey of cesarean section at the New Haven Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984672"}
{"pmid": "20984673", "title": "Facial characteristics of infants with bilateral renal agenesis.", "content": "Facial characteristics of infants with bilateral renal agenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984673"}
{"pmid": "20984674", "title": "Chiari-Frommel syndrome; an historical review with case report.", "content": "Chiari-Frommel syndrome; an historical review with case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984674"}
{"pmid": "20984675", "title": "Heterologous transplantation of human malignant ovarian tumor; report of successful growth of human papillary cystadenocarcinoma in anterior chamber of eye of guinea pig.", "content": "Heterologous transplantation of human malignant ovarian tumor; report of successful growth of human papillary cystadenocarcinoma in anterior chamber of eye of guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984675"}
{"pmid": "20984676", "title": "Extramembranous pregnancy.", "content": "Extramembranous pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984676"}
{"pmid": "20984677", "title": "Hydatidiform mole with severe pre-eclampsia.", "content": "Hydatidiform mole with severe pre-eclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984677"}
{"pmid": "20984678", "title": "Mesonephroma of the Fallopian tube.", "content": "Mesonephroma of the Fallopian tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984678"}
{"pmid": "20984679", "title": "Ovarian pregnancy.", "content": "Ovarian pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984679"}
{"pmid": "20984680", "title": "Prolapsed malignant tumor of the bladder as a complication of pregnancy.", "content": "Prolapsed malignant tumor of the bladder as a complication of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984680"}
{"pmid": "20984681", "title": "Medical rehabilitation.", "content": "Medical rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984681"}
{"pmid": "20984682", "title": "REHABILITATION of ex-service personnel.", "content": "REHABILITATION of ex-service personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984682"}
{"pmid": "20984683", "title": "Dust and infection in children's wards.", "content": "Dust and infection in children's wards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984683"}
{"pmid": "20984684", "title": "PAINLESS childbirth.", "content": "PAINLESS childbirth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984684"}
{"pmid": "20984685", "title": "MEDICINE in industry.", "content": "MEDICINE in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984685"}
{"pmid": "20984686", "title": "PIONEER Health Centre, Peckham.", "content": "PIONEER Health Centre, Peckham.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984686"}
{"pmid": "20984687", "title": "Engineering in hospitals; installation of sterilizers.", "content": "Engineering in hospitals; installation of sterilizers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984687"}
{"pmid": "20984688", "title": "HOSPITAL city of Lille.", "content": "HOSPITAL city of Lille.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984688"}
{"pmid": "20984689", "title": "APPARATUS, equipment and materials of interest to the modern hospital.", "content": "APPARATUS, equipment and materials of interest to the modern hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984689"}
{"pmid": "20984690", "title": "Complete care of infantile paralysis patients demands organization of the community.", "content": "Complete care of infantile paralysis patients demands organization of the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984690"}
{"pmid": "20984691", "title": "From a general hospital that admitted poliomyelitis patients.", "content": "From a general hospital that admitted poliomyelitis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984691"}
{"pmid": "20984692", "title": "Essential services are assured by the National Foundation.", "content": "Essential services are assured by the National Foundation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984692"}
{"pmid": "20984693", "title": "General hospitals have the responsibility.", "content": "General hospitals have the responsibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984693"}
{"pmid": "20984694", "title": "Utah now knows how to cope with a siege of poliomyelitis.", "content": "Utah now knows how to cope with a siege of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984694"}
{"pmid": "20984695", "title": "Polio emergency brings nursing service special responsibilities.", "content": "Polio emergency brings nursing service special responsibilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984695"}
{"pmid": "20984696", "title": "Longe range insurance for all general hospitals; the department of physical medicine.", "content": "Longe range insurance for all general hospitals; the department of physical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984696"}
{"pmid": "20984698", "title": "What research teaches so far about infantile paralysis.", "content": "What research teaches so far about infantile paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984698"}
{"pmid": "20984699", "title": "Seasonal behavior of polio.", "content": "Seasonal behavior of polio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984699"}
{"pmid": "20984697", "title": "Lasting deformity can be minimized by muscle conservation.", "content": "Lasting deformity can be minimized by muscle conservation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984697"}
{"pmid": "20984700", "title": "Some practical new developments in dietary equipment.", "content": "Some practical new developments in dietary equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984700"}
{"pmid": "20984701", "title": "Why the returning administrator should study other hospitals.", "content": "Why the returning administrator should study other hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984701"}
{"pmid": "20984702", "title": "Emergency air ambulance serves Saskatchewan.", "content": "Emergency air ambulance serves Saskatchewan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984702"}
{"pmid": "20984703", "title": "Organizing the pharmacy for preparation of sterile medications.", "content": "Organizing the pharmacy for preparation of sterile medications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984703"}
{"pmid": "20984704", "title": "Morale can be determined and bettered by survey.", "content": "Morale can be determined and bettered by survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984704"}
{"pmid": "20984705", "title": "Industrial health department functions and relationships; preliminary report of a foundation field study now in progress.", "content": "Industrial health department functions and relationships; preliminary report of a foundation field study now in progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984705"}
{"pmid": "20984706", "title": "Accurate diagnosis of silicosis; possible sources of error.", "content": "Accurate diagnosis of silicosis; possible sources of error.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984706"}
{"pmid": "20984707", "title": "Accurate diagnosis of silicosis; some example of error.", "content": "Accurate diagnosis of silicosis; some example of error.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984707"}
{"pmid": "20984708", "title": "Accurate diagnosis of silicosis; atypical nodulation in foundry grinders and burners.", "content": "Accurate diagnosis of silicosis; atypical nodulation in foundry grinders and burners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984708"}
{"pmid": "20984709", "title": "Accurate measurement of silicosis hazards; newer methods.", "content": "Accurate measurement of silicosis hazards; newer methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984709"}
{"pmid": "20984710", "title": "Controlling industrial health hazards.", "content": "Controlling industrial health hazards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984710"}
{"pmid": "20984735", "title": "Vitamin B deficiency-states.", "content": "Vitamin B deficiency-states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984735"}
{"pmid": "20984736", "title": "Evaluation of synthetic antiseptics.", "content": "Evaluation of synthetic antiseptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984736"}
{"pmid": "20984737", "title": "Pharmacology of penicillin.", "content": "Pharmacology of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984737"}
{"pmid": "20984738", "title": "Diphtheritic conjunctivitis complicating septicaemia; case report with review of literature of last 15 years.", "content": "Diphtheritic conjunctivitis complicating septicaemia; case report with review of literature of last 15 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984738"}
{"pmid": "20984739", "title": "Enuresis.", "content": "Enuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984739"}
{"pmid": "20984740", "title": "The role of liver in health and disease.", "content": "The role of liver in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984740"}
{"pmid": "20984741", "title": "Erysipelas.", "content": "Erysipelas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984741"}
{"pmid": "20984743", "title": "Drugs and how they influence the cure.", "content": "Drugs and how they influence the cure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984743"}
{"pmid": "20984742", "title": "Treatment of marasmus.", "content": "Treatment of marasmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984742"}
{"pmid": "20984744", "title": "A crusade against high blood pressure.", "content": "A crusade against high blood pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984744"}
{"pmid": "20984745", "title": "Abdominal pain in young children.", "content": "Abdominal pain in young children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984745"}
{"pmid": "20984746", "title": "Scurvy.", "content": "Scurvy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984746"}
{"pmid": "20984747", "title": "Penicillin in the eye diseases.", "content": "Penicillin in the eye diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984747"}
{"pmid": "20984748", "title": "Malarial nephritis.", "content": "Malarial nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984748"}
{"pmid": "20984749", "title": "A case of paroxysmal tachycardia due to malaria.", "content": "A case of paroxysmal tachycardia due to malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984749"}
{"pmid": "20984750", "title": "A case of cerebral malarial fever with paralytic manifestations.", "content": "A case of cerebral malarial fever with paralytic manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984750"}
{"pmid": "20984751", "title": "A case of malaria complicated with round worms.", "content": "A case of malaria complicated with round worms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984751"}
{"pmid": "20984756", "title": "A bizarre type of seven day fever clinically indistinguishable from dengue.", "content": "A bizarre type of seven day fever clinically indistinguishable from dengue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984756"}
{"pmid": "20984757", "title": "Moschcowitz procedure.", "content": "Moschcowitz procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984757"}
{"pmid": "20984764", "title": "Progress in the control of leprosy in the British Empire.", "content": "Progress in the control of leprosy in the British Empire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984764"}
{"pmid": "20984765", "title": "Therapeutic action of different penicillins on Spirochaeta recurrentis infections in mice.", "content": "Therapeutic action of different penicillins on Spirochaeta recurrentis infections in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984765"}
{"pmid": "20984767", "title": "The diets of families with children in 1941.", "content": "The diets of families with children in 1941.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984767"}
{"pmid": "20984766", "title": "Neurogenic ileus.", "content": "Neurogenic ileus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984766"}
{"pmid": "20984768", "title": "Extra-oral nerve-block analgesia for dental extractions.", "content": "Extra-oral nerve-block analgesia for dental extractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984768"}
{"pmid": "20984769", "title": "Paradoxical embolism.", "content": "Paradoxical embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984769"}
{"pmid": "20984770", "title": "The scientific method in clinical medicine.", "content": "The scientific method in clinical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984770"}
{"pmid": "20984771", "title": "PENICILLIN in subacute bacterial endocarditis.", "content": "PENICILLIN in subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984771"}
{"pmid": "20984772", "title": "The source and transmission of nasopharyngeal infections due to certain bacteria and viruses.", "content": "The source and transmission of nasopharyngeal infections due to certain bacteria and viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984772"}
{"pmid": "20984774", "title": "Thomas and his splint.", "content": "Thomas and his splint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984774"}
{"pmid": "20984773", "title": "Amphetamine and caffeine citrate in anoxaemia.", "content": "Amphetamine and caffeine citrate in anoxaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984773"}
{"pmid": "20984775", "title": "The importance of autoregulation in nitrogen metabolism.", "content": "The importance of autoregulation in nitrogen metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984775"}
{"pmid": "20984776", "title": "Agranulocytosis due to novaldin.", "content": "Agranulocytosis due to novaldin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984776"}
{"pmid": "20984777", "title": "A note on external otitis.", "content": "A note on external otitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984777"}
{"pmid": "20984778", "title": "DEVASTATED medical libraries.", "content": "DEVASTATED medical libraries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984778"}
{"pmid": "20984779", "title": "Smallpox in the vaccinated.", "content": "Smallpox in the vaccinated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984779"}
{"pmid": "20984780", "title": "Roentgen therapy for acute inflammations.", "content": "Roentgen therapy for acute inflammations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984780"}
{"pmid": "20984781", "title": "The preoperative and postoperative care of patients.", "content": "The preoperative and postoperative care of patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984781"}
{"pmid": "20984782", "title": "Edema of the corneal epithelium caused by atabrine; observation on three patients.", "content": "Edema of the corneal epithelium caused by atabrine; observation on three patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984782"}
{"pmid": "20984783", "title": "Sodium caprylate; a new and effective treatment for moniliasis of the skin and mucous membranes.", "content": "Sodium caprylate; a new and effective treatment for moniliasis of the skin and mucous membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984783"}
{"pmid": "20984784", "title": "Toxic and immunological properties of pneumococcal hemolysin.", "content": "Toxic and immunological properties of pneumococcal hemolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984784"}
{"pmid": "20984792", "title": "Diaphragmatic herniation, pleuroperitoneal hiatus with case report.", "content": "Diaphragmatic herniation, pleuroperitoneal hiatus with case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984792"}
{"pmid": "20984793", "title": "Medicine and the public.", "content": "Medicine and the public.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984793"}
{"pmid": "20984794", "title": "Does the public want health?", "content": "Does the public want health?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984794"}
{"pmid": "20984795", "title": "Protein needs of the aged surgical patient.", "content": "Protein needs of the aged surgical patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984795"}
{"pmid": "20984796", "title": "Acute pulmonary edema; report of case.", "content": "Acute pulmonary edema; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984796"}
{"pmid": "20984816", "title": "Prevention of complications following abdominal surgery.", "content": "Prevention of complications following abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984816"}
{"pmid": "20984818", "title": "The general treatment of arthritis.", "content": "The general treatment of arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984818"}
{"pmid": "20984817", "title": "Danger of confusing hypermetabolism with hyperthyroidism.", "content": "Danger of confusing hypermetabolism with hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984817"}
{"pmid": "20984819", "title": "Rheumatic fever; diagnostic problems encountered on a rheumatic fever service.", "content": "Rheumatic fever; diagnostic problems encountered on a rheumatic fever service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984819"}
{"pmid": "20984820", "title": "Physician's workshop.", "content": "Physician's workshop.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984820"}
{"pmid": "20984821", "title": "INTRACRANIAL hemorrhage in the new born; convulsions in the new born.", "content": "INTRACRANIAL hemorrhage in the new born; convulsions in the new born.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984821"}
{"pmid": "20984828", "title": "The health and welfare of the merchant seaman.", "content": "The health and welfare of the merchant seaman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984828"}
{"pmid": "20984829", "title": "Dysphagia due to causes other than malignant disease.", "content": "Dysphagia due to causes other than malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984829"}
{"pmid": "20984830", "title": "The experiences of an otologist on active service.", "content": "The experiences of an otologist on active service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984830"}
{"pmid": "20984831", "title": "Meningococcaemia; three cases and a historical review.", "content": "Meningococcaemia; three cases and a historical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984831"}
{"pmid": "20984847", "title": "Hygiene and sanitation among the Bedouins in Palestine.", "content": "Hygiene and sanitation among the Bedouins in Palestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984847"}
{"pmid": "20984848", "title": "Impression of my flying trip to Palestine.", "content": "Impression of my flying trip to Palestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984848"}
{"pmid": "20984849", "title": "The anemias and their treatment in the light of recent advances.", "content": "The anemias and their treatment in the light of recent advances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984849"}
{"pmid": "20984850", "title": "The menopause; an endocrine dysfunction.", "content": "The menopause; an endocrine dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984850"}
{"pmid": "20984851", "title": "Recent advances in urology.", "content": "Recent advances in urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984851"}
{"pmid": "20984868", "title": "Floating specks.", "content": "Floating specks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984868"}
{"pmid": "20984869", "title": "The use and abuse of midwifery forceps.", "content": "The use and abuse of midwifery forceps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984869"}
{"pmid": "20984870", "title": "The value of sulphathiazole in acute bacillary dysentery.", "content": "The value of sulphathiazole in acute bacillary dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984870"}
{"pmid": "20984871", "title": "Cancer and its prevention.", "content": "Cancer and its prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984871"}
{"pmid": "20984872", "title": "Cruveilhier-Baumgarten syndrome.", "content": "Cruveilhier-Baumgarten syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984872"}
{"pmid": "20984874", "title": "Studies in anaemias.", "content": "Studies in anaemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984874"}
{"pmid": "20984873", "title": "The auricular wave; an exhaustive inquiry into the physiological and pathological variations of the P wave (or auricular wave) of the electrocardiogram.", "content": "The auricular wave; an exhaustive inquiry into the physiological and pathological variations of the P wave (or auricular wave) of the electrocardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984873"}
{"pmid": "20984875", "title": "Laxatives and purgatives or cathartics.", "content": "Laxatives and purgatives or cathartics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984875"}
{"pmid": "20984876", "title": "Bronchoscopy in the treatment of post-lobectomy atelectasis.", "content": "Bronchoscopy in the treatment of post-lobectomy atelectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984876"}
{"pmid": "20984877", "title": "Toxic reactions to massive vitamin B1 therapy.", "content": "Toxic reactions to massive vitamin B1 therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984877"}
{"pmid": "20984878", "title": "Isolation of Mycobacterium leprae in culture.", "content": "Isolation of Mycobacterium leprae in culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984878"}
{"pmid": "20984879", "title": "Prolapse of the rectum.", "content": "Prolapse of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984879"}
{"pmid": "20984880", "title": "A doctor and his books.", "content": "A doctor and his books.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984880"}
{"pmid": "20984881", "title": "The treatment of habitual constipation by explanatory suggestion.", "content": "The treatment of habitual constipation by explanatory suggestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984881"}
{"pmid": "20984882", "title": "Paget's disease of bone; a review with a case report.", "content": "Paget's disease of bone; a review with a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984882"}
{"pmid": "20984883", "title": "Congenital hypertrophic pyloric stenosis.", "content": "Congenital hypertrophic pyloric stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984883"}
{"pmid": "20984884", "title": "The perpetuation of nervous disorders by Army psychiatric procedure.", "content": "The perpetuation of nervous disorders by Army psychiatric procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984884"}
{"pmid": "20984885", "title": "Nitrogen mustards in the treatment of neoplastic disease; official statement.", "content": "Nitrogen mustards in the treatment of neoplastic disease; official statement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984885"}
{"pmid": "20984886", "title": "Pulmonary calcification and sensitivity to histoplasmin, tuberculin and haplosporangin.", "content": "Pulmonary calcification and sensitivity to histoplasmin, tuberculin and haplosporangin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984886"}
{"pmid": "20984887", "title": "Amphetamine (benzedrine) sulfate for acute barbiturate poisoning.", "content": "Amphetamine (benzedrine) sulfate for acute barbiturate poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984887"}
{"pmid": "20984888", "title": "Meningitis due to Escherichia coli treated with streptomycin.", "content": "Meningitis due to Escherichia coli treated with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984888"}
{"pmid": "20984889", "title": "Tropical medicine.", "content": "Tropical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984889"}
{"pmid": "20984890", "title": "The use of thiouracil in thyroid surgery.", "content": "The use of thiouracil in thyroid surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984890"}
{"pmid": "20984891", "title": "Three-and-a-half years in the Royal Army Medical Corps.", "content": "Three-and-a-half years in the Royal Army Medical Corps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984891"}
{"pmid": "20984892", "title": "Period of internment in Stanley Camp, Hong Kong, January 1941 to September 1945.", "content": "Period of internment in Stanley Camp, Hong Kong, January 1941 to September 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984892"}
{"pmid": "20984893", "title": "Cancer control in Canada.", "content": "Cancer control in Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984893"}
{"pmid": "20984894", "title": "Spontaneous hypoglycemia.", "content": "Spontaneous hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984894"}
{"pmid": "20984895", "title": "High fever of obscure etiology; with report of a case.", "content": "High fever of obscure etiology; with report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984895"}
{"pmid": "20984896", "title": "Dangers in estrogen therapy; with especial reference to synthetic estrogens in menopausal therapy.", "content": "Dangers in estrogen therapy; with especial reference to synthetic estrogens in menopausal therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984896"}
{"pmid": "20984897", "title": "Esophageal varices and their treatment.", "content": "Esophageal varices and their treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984897"}
{"pmid": "20984898", "title": "Tracheotomy.", "content": "Tracheotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984898"}
{"pmid": "20984899", "title": "Intrathecal penicillin in pneumococcic meningitis; case report.", "content": "Intrathecal penicillin in pneumococcic meningitis; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984899"}
{"pmid": "20984900", "title": "Postwar venereal disease problems and treatment.", "content": "Postwar venereal disease problems and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984900"}
{"pmid": "20984901", "title": "Remarks on early syphilis.", "content": "Remarks on early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984901"}
{"pmid": "20984902", "title": "The clinic in venereal disease control.", "content": "The clinic in venereal disease control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984902"}
{"pmid": "20984903", "title": "Newer methods of treatment of gonorrhea.", "content": "Newer methods of treatment of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984903"}
{"pmid": "20984904", "title": "Penicillin therapy in genito-urinary tract infections.", "content": "Penicillin therapy in genito-urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984904"}
{"pmid": "20984905", "title": "Some diagnostic and serologic problems in the present-day management of syphilis.", "content": "Some diagnostic and serologic problems in the present-day management of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984905"}
{"pmid": "20984906", "title": "Serologic trends and aspects.", "content": "Serologic trends and aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984906"}
{"pmid": "20984907", "title": "Venereal disease.", "content": "Venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984907"}
{"pmid": "20984908", "title": "The influence of serendipity on medicine.", "content": "The influence of serendipity on medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984908"}
{"pmid": "20984909", "title": "The mentally ill.", "content": "The mentally ill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984909"}
{"pmid": "20984910", "title": "Some clinical experiences with benadryl.", "content": "Some clinical experiences with benadryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984910"}
{"pmid": "20984911", "title": "Better health through health education.", "content": "Better health through health education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984911"}
{"pmid": "20984912", "title": "Recent advances in the chemotherapy of malaria.", "content": "Recent advances in the chemotherapy of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984912"}
{"pmid": "20984913", "title": "Health education today and tomorrow.", "content": "Health education today and tomorrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984913"}
{"pmid": "20984914", "title": "The use of intravenous alcohol for postoperative analgesia and sedation.", "content": "The use of intravenous alcohol for postoperative analgesia and sedation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984914"}
{"pmid": "20984915", "title": "Obstetrics and pediatric meddling.", "content": "Obstetrics and pediatric meddling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984915"}
{"pmid": "20984920", "title": "RURAL medicine, community hospitals and metropolitan assistance.", "content": "RURAL medicine, community hospitals and metropolitan assistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984920"}
{"pmid": "20984921", "title": "Penicillin and sulfonamides in the treatment of pneumonias.", "content": "Penicillin and sulfonamides in the treatment of pneumonias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984921"}
{"pmid": "20984922", "title": "The roentgen diagnosis of tumors of the lung.", "content": "The roentgen diagnosis of tumors of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984922"}
{"pmid": "20984923", "title": "Surgical treatment of bronchiectasis.", "content": "Surgical treatment of bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984923"}
{"pmid": "20984924", "title": "Cysts of the mediastinum and lungs.", "content": "Cysts of the mediastinum and lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984924"}
{"pmid": "20984925", "title": "The importance of bronchiogenic carcinoma to the general practitioner.", "content": "The importance of bronchiogenic carcinoma to the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984925"}
{"pmid": "20984926", "title": "Penicillin and the general practitioner.", "content": "Penicillin and the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984926"}
{"pmid": "20984927", "title": "An epidemic of influenza B in Australia.", "content": "An epidemic of influenza B in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984927"}
{"pmid": "20984928", "title": "Cortical mastoidectomy; use of penicillin in plasma clot.", "content": "Cortical mastoidectomy; use of penicillin in plasma clot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984928"}
{"pmid": "20984929", "title": "Haemolytic icterus (acholuric jaundice) congenital and acquired.", "content": "Haemolytic icterus (acholuric jaundice) congenital and acquired.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984929"}
{"pmid": "20984931", "title": "RISE of endocrinology.", "content": "RISE of endocrinology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984931"}
{"pmid": "20984930", "title": "Relation of the adrenal cortex to arthritis.", "content": "Relation of the adrenal cortex to arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984930"}
{"pmid": "20984940", "title": "The protruding ear and its surgical treatment.", "content": "The protruding ear and its surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984940"}
{"pmid": "20984941", "title": "On angina pectoris.", "content": "On angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984941"}
{"pmid": "20984942", "title": "Remarks on tuberculosis.", "content": "Remarks on tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984942"}
{"pmid": "20984943", "title": "Elephantiasis, with special reference to non-parasitic forms.", "content": "Elephantiasis, with special reference to non-parasitic forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984943"}
{"pmid": "20984944", "title": "Manitoba Medical Centre.", "content": "Manitoba Medical Centre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984944"}
{"pmid": "20984953", "title": "Further observations on rat leprosy.", "content": "Further observations on rat leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984953"}
{"pmid": "20984954", "title": "Clinical aspects of foetal erythroblastosis.", "content": "Clinical aspects of foetal erythroblastosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984954"}
{"pmid": "20984955", "title": "Non-gonococcal urethritis in Australian troops stationed in Borneo.", "content": "Non-gonococcal urethritis in Australian troops stationed in Borneo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984955"}
{"pmid": "20984956", "title": "Chromoblastomycosis, with reports of two cases occurring in Queensland.", "content": "Chromoblastomycosis, with reports of two cases occurring in Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984956"}
{"pmid": "20984958", "title": "Congenital stricture of the oesophagus.", "content": "Congenital stricture of the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984958"}
{"pmid": "20984957", "title": "A case of post-varicellal encephalitis showing bilateral softening of the neostriatum and terminal tetanoid chorea (Gowers).", "content": "A case of post-varicellal encephalitis showing bilateral softening of the neostriatum and terminal tetanoid chorea (Gowers).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984957"}
{"pmid": "20984960", "title": "Medical progress in the 20th century.", "content": "Medical progress in the 20th century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984960"}
{"pmid": "20984962", "title": "Cavernous sinus thrombosis with recovery; report of case.", "content": "Cavernous sinus thrombosis with recovery; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984962"}
{"pmid": "20984961", "title": "What socialized medicine means to Mississippi.", "content": "What socialized medicine means to Mississippi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984961"}
{"pmid": "20984963", "title": "The Rh factor in medicine.", "content": "The Rh factor in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984963"}
{"pmid": "20984964", "title": "Fiberglas packs in pelvic surgery.", "content": "Fiberglas packs in pelvic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984964"}
{"pmid": "20984965", "title": "The function of the coroner's office in relation to the physician.", "content": "The function of the coroner's office in relation to the physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984965"}
{"pmid": "20984966", "title": "Vital statistics; their relationship to the physician and to the board of health.", "content": "Vital statistics; their relationship to the physician and to the board of health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984966"}
{"pmid": "20984967", "title": "Two interesting cases of rectovaginal repair.", "content": "Two interesting cases of rectovaginal repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984967"}
{"pmid": "20984968", "title": "Phlegmonous cecitis.", "content": "Phlegmonous cecitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984968"}
{"pmid": "20984969", "title": "Injuries to the shoulder.", "content": "Injuries to the shoulder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984969"}
{"pmid": "20984970", "title": "Impending ischemic gangrene; new non-surgical therapeutic suggestions (a preliminary report).", "content": "Impending ischemic gangrene; new non-surgical therapeutic suggestions (a preliminary report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984970"}
{"pmid": "20984971", "title": "A method of approach in a veterans' psychiatric clinic.", "content": "A method of approach in a veterans' psychiatric clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984971"}
{"pmid": "20984972", "title": "Thoracolumbar sympathectomy in the treatment of advanced essential hypertension.", "content": "Thoracolumbar sympathectomy in the treatment of advanced essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984972"}
{"pmid": "20984973", "title": "The differential diagnosis between recurrent postoperative cholelithiasis and recurrent or chronic parenchymatous hepatitis.", "content": "The differential diagnosis between recurrent postoperative cholelithiasis and recurrent or chronic parenchymatous hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984973"}
{"pmid": "20984974", "title": "Progress in physical medicine during the past twenty-five years.", "content": "Progress in physical medicine during the past twenty-five years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984974"}
{"pmid": "20984975", "title": "Benzhydryl ether hydrochloride (benadryl) in the symptomatic treatment of allergy.", "content": "Benzhydryl ether hydrochloride (benadryl) in the symptomatic treatment of allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984975"}
{"pmid": "20984976", "title": "An unusual toxic reaction to a mercurial diuretic.", "content": "An unusual toxic reaction to a mercurial diuretic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984976"}
{"pmid": "20984977", "title": "Injury to the ureter during appendectomy.", "content": "Injury to the ureter during appendectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984977"}
{"pmid": "20984979", "title": "Acute pancreatitis.", "content": "Acute pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984979"}
{"pmid": "20984978", "title": "Subconjunctival luxation of the lens due to indirect trauma with good visual recovery.", "content": "Subconjunctival luxation of the lens due to indirect trauma with good visual recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984978"}
{"pmid": "20984980", "title": "Treatment of meningitis.", "content": "Treatment of meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984980"}
{"pmid": "20984981", "title": "POLIOMYELITIS in New Zealand.", "content": "POLIOMYELITIS in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984981"}
{"pmid": "20984982", "title": "OPHTHALMOLOGICAL Society in New Zealand.", "content": "OPHTHALMOLOGICAL Society in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984982"}
{"pmid": "20984983", "title": "Hyperparathyroidism and parathyroid adenoma; three New Zealand cases.", "content": "Hyperparathyroidism and parathyroid adenoma; three New Zealand cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984983"}
{"pmid": "20984984", "title": "On diarrhoea.", "content": "On diarrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984984"}
{"pmid": "20984985", "title": "The incidence of tuberculosis among medical students and the younger graduates in New Zealand.", "content": "The incidence of tuberculosis among medical students and the younger graduates in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984985"}
{"pmid": "20984986", "title": "Blood transfusion a century ago.", "content": "Blood transfusion a century ago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984986"}
{"pmid": "20984987", "title": "The pathogenesis and clinical value of spontaneous sensory phenomena with organic disease of the brain.", "content": "The pathogenesis and clinical value of spontaneous sensory phenomena with organic disease of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984987"}
{"pmid": "20984989", "title": "Prisoners of War in Japan.", "content": "Prisoners of War in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984989"}
{"pmid": "20984988", "title": "Congenital duodenal stenosis; report of a case.", "content": "Congenital duodenal stenosis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984988"}
{"pmid": "20984990", "title": "Neurologist and neurosurgeon.", "content": "Neurologist and neurosurgeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984990"}
{"pmid": "20984991", "title": "Carotinaemia and acute appendicitis.", "content": "Carotinaemia and acute appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984991"}
{"pmid": "20984992", "title": "Present status of the proposals for medical care in North Carolina.", "content": "Present status of the proposals for medical care in North Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984992"}
{"pmid": "20984993", "title": "Commencement address.", "content": "Commencement address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984993"}
{"pmid": "20984994", "title": "Difficulties in the diagnosis and treatment of pinworm infection.", "content": "Difficulties in the diagnosis and treatment of pinworm infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984994"}
{"pmid": "20984995", "title": "Spirochetal jaundice (Weil's disease) in North Carolina.", "content": "Spirochetal jaundice (Weil's disease) in North Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984995"}
{"pmid": "20984996", "title": "The management of acute psychiatric cases in general practice.", "content": "The management of acute psychiatric cases in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984996"}
{"pmid": "20984997", "title": "Caudal analgesia.", "content": "Caudal analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984997"}
{"pmid": "20984998", "title": "Atomic energy and cancer.", "content": "Atomic energy and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20984998"}
{"pmid": "20985025", "title": "The catarrhal child.", "content": "The catarrhal child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985025"}
{"pmid": "20985026", "title": "Radiotherapy and cancer.", "content": "Radiotherapy and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985026"}
{"pmid": "20985027", "title": "The treatment of suppurative otitis media.", "content": "The treatment of suppurative otitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985027"}
{"pmid": "20985028", "title": "Microcrystalline sulphathiazole in abdominal surgery; a preliminary report.", "content": "Microcrystalline sulphathiazole in abdominal surgery; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985028"}
{"pmid": "20985029", "title": "The spastic colon.", "content": "The spastic colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985029"}
{"pmid": "20985030", "title": "Diverticulitis and diverticulosis.", "content": "Diverticulitis and diverticulosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985030"}
{"pmid": "20985031", "title": "Carcinoma of the colon.", "content": "Carcinoma of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985031"}
{"pmid": "20985032", "title": "Hirschsprung's disease.", "content": "Hirschsprung's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985032"}
{"pmid": "20985033", "title": "Ulcerative colitis.", "content": "Ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985033"}
{"pmid": "20985034", "title": "Constipation.", "content": "Constipation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985034"}
{"pmid": "20985035", "title": "Some minor medical maladies of old age.", "content": "Some minor medical maladies of old age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985035"}
{"pmid": "20985036", "title": "The treatment of chronic faucial diphtheria by tonsillectomy.", "content": "The treatment of chronic faucial diphtheria by tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985036"}
{"pmid": "20985037", "title": "Dyspepsia of peptic ulcer type and its relationship to personality type and anxiety.", "content": "Dyspepsia of peptic ulcer type and its relationship to personality type and anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985037"}
{"pmid": "20985038", "title": "Early recognition of disease; mental disorders.", "content": "Early recognition of disease; mental disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985038"}
{"pmid": "20985039", "title": "The treatment of dysmenorrhoea.", "content": "The treatment of dysmenorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985039"}
{"pmid": "20985041", "title": "Indications for blood transfusion.", "content": "Indications for blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985041"}
{"pmid": "20985040", "title": "The female sex hormones.", "content": "The female sex hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985040"}
{"pmid": "20985072", "title": "Penicillin; a drug of diffusion.", "content": "Penicillin; a drug of diffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985072"}
{"pmid": "20985073", "title": "The main blood streams in the reptile heart.", "content": "The main blood streams in the reptile heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985073"}
{"pmid": "20985074", "title": "THE cholera scare of 1831.", "content": "THE cholera scare of 1831.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985074"}
{"pmid": "20985075", "title": "Mode of action of yeast extracts in accelerating peroxidase activity.", "content": "Mode of action of yeast extracts in accelerating peroxidase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985075"}
{"pmid": "20985076", "title": "Effect of rabbit spleen extract and spleen pulp on mouse carcinoma.", "content": "Effect of rabbit spleen extract and spleen pulp on mouse carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985076"}
{"pmid": "20985077", "title": "Effect of yeast extract on various peroxidatic reactions.", "content": "Effect of yeast extract on various peroxidatic reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985077"}
{"pmid": "20985078", "title": "Ultraviolet absorption of some organic compounds; aromatic compounds.", "content": "Ultraviolet absorption of some organic compounds; aromatic compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985078"}
{"pmid": "20985079", "title": "A growth-promoting factor produced by ultraviolet irradiation of Stichococcus bacillaris Naegeli and Stichococcus flaccidus (Kutz) Gay.", "content": "A growth-promoting factor produced by ultraviolet irradiation of Stichococcus bacillaris Naegeli and Stichococcus flaccidus (Kutz) Gay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985079"}
{"pmid": "20985080", "title": "Proliferation-promoting properties of hydrolyzed nucleic acid.", "content": "Proliferation-promoting properties of hydrolyzed nucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985080"}
{"pmid": "20985082", "title": "Effect of para-aminobenzoic acid and other substances on yeast respiration and on the respiratory-depressant action of phenylmercuric nitrate.", "content": "Effect of para-aminobenzoic acid and other substances on yeast respiration and on the respiratory-depressant action of phenylmercuric nitrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985082"}
{"pmid": "20985081", "title": "Effect of yeast extract on the growth and respiration of Azotobacter chroococcum.", "content": "Effect of yeast extract on the growth and respiration of Azotobacter chroococcum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985081"}
{"pmid": "20985083", "title": "Action of yeast extracts in stimulating animal tissue respiration.", "content": "Action of yeast extracts in stimulating animal tissue respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985083"}
{"pmid": "20985084", "title": "Effect of various tissues extracts on the growth of colontyphoid-dysentery organisms.", "content": "Effect of various tissues extracts on the growth of colontyphoid-dysentery organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985084"}
{"pmid": "20985085", "title": "Effect of the filtrate of ultraviolet irradiated Stichococcus bacillaris Naegeli upon the chlorophyll and carbohydrate content of algae.", "content": "Effect of the filtrate of ultraviolet irradiated Stichococcus bacillaris Naegeli upon the chlorophyll and carbohydrate content of algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985085"}
{"pmid": "20985086", "title": "Depression of tissue and yeast respiration by local anesthetics.", "content": "Depression of tissue and yeast respiration by local anesthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985086"}
{"pmid": "20985087", "title": "Effect of tissue extracts on growth of avirulent and virulent tubercle bacilli in vitro.", "content": "Effect of tissue extracts on growth of avirulent and virulent tubercle bacilli in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985087"}
{"pmid": "20985102", "title": "Venous thrombosis in the upper extremity.", "content": "Venous thrombosis in the upper extremity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985102"}
{"pmid": "20985103", "title": "Complications following thermal injury to the respiratory tract; a case report.", "content": "Complications following thermal injury to the respiratory tract; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985103"}
{"pmid": "20985104", "title": "Histoplasmosis; reticulo-endothelial cytomycosis.", "content": "Histoplasmosis; reticulo-endothelial cytomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985104"}
{"pmid": "20985105", "title": "Treatment of some anxiety states.", "content": "Treatment of some anxiety states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985105"}
{"pmid": "20985106", "title": "Epidemiologic study of a primary syphilis case.", "content": "Epidemiologic study of a primary syphilis case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985106"}
{"pmid": "20985107", "title": "The cephalin-cholesterol flocculation test of Hanger.", "content": "The cephalin-cholesterol flocculation test of Hanger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985107"}
{"pmid": "20985121", "title": "Management of acute craniocephalic injuries of war; methods applied in evacuation hospitals of the Southwest Pacific Theater of Operations.", "content": "Management of acute craniocephalic injuries of war; methods applied in evacuation hospitals of the Southwest Pacific Theater of Operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985121"}
{"pmid": "20985122", "title": "Some personal experiences in the treatment of war gas burns of the upper respiratory tract during World War II.", "content": "Some personal experiences in the treatment of war gas burns of the upper respiratory tract during World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985122"}
{"pmid": "20985123", "title": "Some observations on the fractured carpal scaphoid.", "content": "Some observations on the fractured carpal scaphoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985123"}
{"pmid": "20985124", "title": "An informal report on fusospirochetosis.", "content": "An informal report on fusospirochetosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985124"}
{"pmid": "20985125", "title": "The significance of the blood alcohol determination.", "content": "The significance of the blood alcohol determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985125"}
{"pmid": "20985126", "title": "Attitude conditioning for postwar trainees.", "content": "Attitude conditioning for postwar trainees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985126"}
{"pmid": "20985127", "title": "Acute traumatic tenositis of the tendon calcaneus due to military boots.", "content": "Acute traumatic tenositis of the tendon calcaneus due to military boots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985127"}
{"pmid": "20985128", "title": "Lens marker.", "content": "Lens marker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985128"}
{"pmid": "20985129", "title": "Suggested change in the American Army canteen to increase its efficiency as an eye irrigator.", "content": "Suggested change in the American Army canteen to increase its efficiency as an eye irrigator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985129"}
{"pmid": "20985130", "title": "Joining the medical corps; a case history.", "content": "Joining the medical corps; a case history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985130"}
{"pmid": "20985131", "title": "Piezoelectric crystal measurements of pressure changes in the abdomen of deeply anaesthetized animals during passage of high-velocity missile.", "content": "Piezoelectric crystal measurements of pressure changes in the abdomen of deeply anaesthetized animals during passage of high-velocity missile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985131"}
{"pmid": "20985132", "title": "INFORMATION for persons desiring to enter the Dental Corps of the United States Navy.", "content": "INFORMATION for persons desiring to enter the Dental Corps of the United States Navy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985132"}
{"pmid": "20985133", "title": "On dyes with antipyrine nuclei and on a special case of dehydrogenation.", "content": "On dyes with antipyrine nuclei and on a special case of dehydrogenation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985133"}
{"pmid": "20985134", "title": "Tetraploid kok-saghyz as a variety of improved productivity.", "content": "Tetraploid kok-saghyz as a variety of improved productivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985134"}
{"pmid": "20985135", "title": "Influence of copper upon the potato plant.", "content": "Influence of copper upon the potato plant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985135"}
{"pmid": "20985136", "title": "Function of parathyroid glands in Amphibia.", "content": "Function of parathyroid glands in Amphibia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985136"}
{"pmid": "20985137", "title": "Bioelectric phenomena as viewed in relation to chemical dynamics of the cell.", "content": "Bioelectric phenomena as viewed in relation to chemical dynamics of the cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985137"}
{"pmid": "20985138", "title": "Carbonic anhydrase of blood as affected by reduced atmospheric pressure.", "content": "Carbonic anhydrase of blood as affected by reduced atmospheric pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985138"}
{"pmid": "20985139", "title": "A new method of photographing microscope slides.", "content": "A new method of photographing microscope slides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985139"}
{"pmid": "20985140", "title": "Method for observing surface structure.", "content": "Method for observing surface structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985140"}
{"pmid": "20985141", "title": "Peritoneoscopic photography.", "content": "Peritoneoscopic photography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985141"}
{"pmid": "20985142", "title": "Cinematography of clinical and surgical subjects; a general consideration of equipment and te3chnic.", "content": "Cinematography of clinical and surgical subjects; a general consideration of equipment and te3chnic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985142"}
{"pmid": "20985143", "title": "Spectrophotometric and colorimetric determination of the colors of the TCCA standard color cards.", "content": "Spectrophotometric and colorimetric determination of the colors of the TCCA standard color cards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985143"}
{"pmid": "20985145", "title": "The urinary excretion of penicillin after ingestion with and without adjuvants and following intramuscular infection.", "content": "The urinary excretion of penicillin after ingestion with and without adjuvants and following intramuscular infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985145"}
{"pmid": "20985146", "title": "Studies in laboratory rearing of Anopheles quadrimaculatus Say.", "content": "Studies in laboratory rearing of Anopheles quadrimaculatus Say.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985146"}
{"pmid": "20985147", "title": "AVAILABILITY of radioactive isotopes.", "content": "AVAILABILITY of radioactive isotopes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985147"}
{"pmid": "20985148", "title": "NUCLEAR research institute at Oak Ridge.", "content": "NUCLEAR research institute at Oak Ridge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985148"}
{"pmid": "20985149", "title": "Interpretation of resistance to Fusarium wilt in tomato.", "content": "Interpretation of resistance to Fusarium wilt in tomato.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985149"}
{"pmid": "20985150", "title": "The blood parasites of the blue grouse.", "content": "The blood parasites of the blue grouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985150"}
{"pmid": "20985151", "title": "The relative effectiveness of pure penicillins G, X, and K.", "content": "The relative effectiveness of pure penicillins G, X, and K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985151"}
{"pmid": "20985152", "title": "Cancer research and benefit to patients.", "content": "Cancer research and benefit to patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985152"}
{"pmid": "20985157", "title": "Associated movements in the oculomotor and facial muscles.", "content": "Associated movements in the oculomotor and facial muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985157"}
{"pmid": "20985158", "title": "Toxic psychoses associated with administration of quinacrine.", "content": "Toxic psychoses associated with administration of quinacrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985158"}
{"pmid": "20985159", "title": "Nystagmoid movements and visual perception; their interrelation in monocular diplopia.", "content": "Nystagmoid movements and visual perception; their interrelation in monocular diplopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985159"}
{"pmid": "20985161", "title": "ORGANIZATION of Eastern Association of Electroencephalographers.", "content": "ORGANIZATION of Eastern Association of Electroencephalographers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985161"}
{"pmid": "20985160", "title": "Use of curare in oil in treatment of spasticity following injury of the spinal cord.", "content": "Use of curare in oil in treatment of spasticity following injury of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985160"}
{"pmid": "20985162", "title": "Incidence, clinical characteristics and restitution of war injuries of peripheral nerves.", "content": "Incidence, clinical characteristics and restitution of war injuries of peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985162"}
{"pmid": "20985163", "title": "Management of war injuries of peripheral nerves.", "content": "Management of war injuries of peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985163"}
{"pmid": "20985164", "title": "Function of the United States Naval Hospital.", "content": "Function of the United States Naval Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985164"}
{"pmid": "20985165", "title": "The psychotic patient.", "content": "The psychotic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985165"}
{"pmid": "20985166", "title": "Neuropsychiatric casualties resulting from exposure to atmospheric blast.", "content": "Neuropsychiatric casualties resulting from exposure to atmospheric blast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985166"}
{"pmid": "20985167", "title": "Group therapy of combat fatigue.", "content": "Group therapy of combat fatigue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985167"}
{"pmid": "20985168", "title": "The hospital as a therapeutic institution.", "content": "The hospital as a therapeutic institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985168"}
{"pmid": "20985169", "title": "The Northfield experiment.", "content": "The Northfield experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985169"}
{"pmid": "20985170", "title": "The leaderless group project.", "content": "The leaderless group project.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985170"}
{"pmid": "20985171", "title": "The technique of group therapy.", "content": "The technique of group therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985171"}
{"pmid": "20985172", "title": "Principles and practice of group therapy.", "content": "Principles and practice of group therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985172"}
{"pmid": "20985173", "title": "Notes on a group of ex-prisoners of war.", "content": "Notes on a group of ex-prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985173"}
{"pmid": "20985174", "title": "The cruel vegetarian.", "content": "The cruel vegetarian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985174"}
{"pmid": "20985175", "title": "Psychopathology of pseudo-humbugs and pseudo-bluffers.", "content": "Psychopathology of pseudo-humbugs and pseudo-bluffers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985175"}
{"pmid": "20985176", "title": "The relation of the church to mental hospitals.", "content": "The relation of the church to mental hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985176"}
{"pmid": "20985177", "title": "Psychiatric aspects of the law of homicide.", "content": "Psychiatric aspects of the law of homicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985177"}
{"pmid": "20985178", "title": "The selection of cases for social treatment.", "content": "The selection of cases for social treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985178"}
{"pmid": "20985179", "title": "The value of diagnostic signs for schizophrenia on the Wechsler-Bellevue adult intelligence test.", "content": "The value of diagnostic signs for schizophrenia on the Wechsler-Bellevue adult intelligence test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985179"}
{"pmid": "20985180", "title": "Hospital ship neuropsychiatry.", "content": "Hospital ship neuropsychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985180"}
{"pmid": "20985181", "title": "A five-year study of 112 women parolees of New York State hospitals.", "content": "A five-year study of 112 women parolees of New York State hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985181"}
{"pmid": "20985182", "title": "The selection of patients for the Western State Psychiatric Institute.", "content": "The selection of patients for the Western State Psychiatric Institute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985182"}
{"pmid": "20985183", "title": "A rejected child; problems, treatment and outcome.", "content": "A rejected child; problems, treatment and outcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985183"}
{"pmid": "20985184", "title": "On acting.", "content": "On acting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985184"}
{"pmid": "20985185", "title": "The genesis of reality testing; a general theory of hallucination.", "content": "The genesis of reality testing; a general theory of hallucination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985185"}
{"pmid": "20985186", "title": "Dreams and acting out.", "content": "Dreams and acting out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985186"}
{"pmid": "20985187", "title": "Unconscious factors in group therapy.", "content": "Unconscious factors in group therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985187"}
{"pmid": "20985188", "title": "Psychology of time perception.", "content": "Psychology of time perception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985188"}
{"pmid": "20985190", "title": "Infectious hepatitis.", "content": "Infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985190"}
{"pmid": "20985189", "title": "Early rising in postoperative care.", "content": "Early rising in postoperative care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985189"}
{"pmid": "20985191", "title": "Nursing care of patients with infectious hepatitis.", "content": "Nursing care of patients with infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985191"}
{"pmid": "20985192", "title": "Medical care insurance and the nurse.", "content": "Medical care insurance and the nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985192"}
{"pmid": "20985193", "title": "The drying of plaster casts.", "content": "The drying of plaster casts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985193"}
{"pmid": "20985194", "title": "A new approach to the teaching of nursing arts.", "content": "A new approach to the teaching of nursing arts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985194"}
{"pmid": "20985195", "title": "Dental health in industry; education, nutrition and emergency treatment.", "content": "Dental health in industry; education, nutrition and emergency treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985195"}
{"pmid": "20985196", "title": "Cooperation between industrial physicians, nurses, and safety engineers.", "content": "Cooperation between industrial physicians, nurses, and safety engineers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985196"}
{"pmid": "20985197", "title": "Sunburn, and industrial absenteeism.", "content": "Sunburn, and industrial absenteeism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985197"}
{"pmid": "20985198", "title": "Helping patients to settle down after admission to mental hospital.", "content": "Helping patients to settle down after admission to mental hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985198"}
{"pmid": "20985199", "title": "Osteogenesis imperfecta.", "content": "Osteogenesis imperfecta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985199"}
{"pmid": "20985200", "title": "Diseases of the nose.", "content": "Diseases of the nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985200"}
{"pmid": "20985201", "title": "Staphylococcal infections of newborn infants; blood spread lesions and treatment.", "content": "Staphylococcal infections of newborn infants; blood spread lesions and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985201"}
{"pmid": "20985202", "title": "The value of educational psychology to the sister tutor; progress in a changing world.", "content": "The value of educational psychology to the sister tutor; progress in a changing world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985202"}
{"pmid": "20985203", "title": "Ocular foreign bodies and their sequelae.", "content": "Ocular foreign bodies and their sequelae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985203"}
{"pmid": "20985204", "title": "Some surgical problems in a theatre of war, with special reference to the campaign in Sicily; the general surgical picture.", "content": "Some surgical problems in a theatre of war, with special reference to the campaign in Sicily; the general surgical picture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985204"}
{"pmid": "20985205", "title": "PENICILLIN in plenty.", "content": "PENICILLIN in plenty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985205"}
{"pmid": "20985206", "title": "An improved method of lining the Thomas's knee splint in fractures of the lower limb.", "content": "An improved method of lining the Thomas's knee splint in fractures of the lower limb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985206"}
{"pmid": "20985208", "title": "A contribution to the pathology of Bowman's membrane.", "content": "A contribution to the pathology of Bowman's membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985208"}
{"pmid": "20985209", "title": "Aetiology of iridocyclitis in the African.", "content": "Aetiology of iridocyclitis in the African.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985209"}
{"pmid": "20985210", "title": "Amniotic membrane grafts in caustic burns of the eye (burns of the second degree).", "content": "Amniotic membrane grafts in caustic burns of the eye (burns of the second degree).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985210"}
{"pmid": "20985211", "title": "Quinine amblyopia.", "content": "Quinine amblyopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985211"}
{"pmid": "20985212", "title": "An exophthalmometer for direct measurement.", "content": "An exophthalmometer for direct measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985212"}
{"pmid": "20985213", "title": "The treatment of convergence deficiency, 1933-1944.", "content": "The treatment of convergence deficiency, 1933-1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985213"}
{"pmid": "20985207", "title": "Painless childbirth.", "content": "Painless childbirth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985207"}
{"pmid": "20985214", "title": "The ultra-violet ophthalmoscope.", "content": "The ultra-violet ophthalmoscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985214"}
{"pmid": "20985215", "title": "Moscow Eye Hospital.", "content": "Moscow Eye Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985215"}
{"pmid": "20985216", "title": "The influence of the Stiles-Crawford effect on measurements with the Pulfrich photometer.", "content": "The influence of the Stiles-Crawford effect on measurements with the Pulfrich photometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985216"}
{"pmid": "20985217", "title": "A photoelectric Raman spectrograph for quantitative analysis.", "content": "A photoelectric Raman spectrograph for quantitative analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985217"}
{"pmid": "20985218", "title": "Thermistor bolometers.", "content": "Thermistor bolometers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985218"}
{"pmid": "20985219", "title": "The visibility of objects seen through the atmosphere.", "content": "The visibility of objects seen through the atmosphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985219"}
{"pmid": "20985220", "title": "The sensitivity of human rod and cone vision to infra-red radiation.", "content": "The sensitivity of human rod and cone vision to infra-red radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985220"}
{"pmid": "20985221", "title": "A differential refractometer.", "content": "A differential refractometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985221"}
{"pmid": "20985222", "title": "Macular pigmentation and color discrimination.", "content": "Macular pigmentation and color discrimination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985222"}
{"pmid": "20985224", "title": "Astigmatism and the accommodative unit.", "content": "Astigmatism and the accommodative unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985224"}
{"pmid": "20985223", "title": "Application of telescopic and microscopic spectacles in subnormal vision; introduction and types available.", "content": "Application of telescopic and microscopic spectacles in subnormal vision; introduction and types available.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985223"}
{"pmid": "20985225", "title": "Cycloplegic refractions; results in 1,000 cases.", "content": "Cycloplegic refractions; results in 1,000 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985225"}
{"pmid": "20985226", "title": "NEW B.C. optometry act.", "content": "NEW B.C. optometry act.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985226"}
{"pmid": "20985227", "title": "Ophthalmia neonatorum in England 1884-1944.", "content": "Ophthalmia neonatorum in England 1884-1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985227"}
{"pmid": "20985228", "title": "Ophthalmia neonatorum; a historical résumé and present status in the United States.", "content": "Ophthalmia neonatorum; a historical résumé and present status in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985228"}
{"pmid": "20985229", "title": "An eyesight survey of thirty plants.", "content": "An eyesight survey of thirty plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985229"}
{"pmid": "20985230", "title": "A public school program for the visually handicapped in Oregon.", "content": "A public school program for the visually handicapped in Oregon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985230"}
{"pmid": "20985231", "title": "Industrial first aid in chemical injuries of the eye.", "content": "Industrial first aid in chemical injuries of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985231"}
{"pmid": "20985232", "title": "Guarding your eyes.", "content": "Guarding your eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985232"}
{"pmid": "20985233", "title": "A study of the usefulness of objective measures of mechanical aptitude in guidance programs for the hypacousic.", "content": "A study of the usefulness of objective measures of mechanical aptitude in guidance programs for the hypacousic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985233"}
{"pmid": "20985234", "title": "The deaf worker in industry.", "content": "The deaf worker in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985234"}
{"pmid": "20985235", "title": "Treatment and training of the hard of hearing; a program of physical and psychosocial therapy.", "content": "Treatment and training of the hard of hearing; a program of physical and psychosocial therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985235"}
{"pmid": "20985236", "title": "Washington County (Maryland) program for the Prevention of deafness in children.", "content": "Washington County (Maryland) program for the Prevention of deafness in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985236"}
{"pmid": "20985237", "title": "Irradiation for the elimination of nasopharyngeal lymphoid tissue.", "content": "Irradiation for the elimination of nasopharyngeal lymphoid tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985237"}
{"pmid": "20985238", "title": "Disturbances of the ethmoid branches of the ophthalmic nerve, with description of a syndrome associated with chronic suppuration of the olfactory fissure.", "content": "Disturbances of the ethmoid branches of the ophthalmic nerve, with description of a syndrome associated with chronic suppuration of the olfactory fissure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985238"}
{"pmid": "20985240", "title": "Foreign body involving the maxillary antrum.", "content": "Foreign body involving the maxillary antrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985240"}
{"pmid": "20985239", "title": "Aero-otitis media in pressure chamber flights.", "content": "Aero-otitis media in pressure chamber flights.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985239"}
{"pmid": "20985241", "title": "Corrosive injuries of the oesophagus; with pàrticular reference to the treatment of acute corrosive oesophagitis.", "content": "Corrosive injuries of the oesophagus; with pàrticular reference to the treatment of acute corrosive oesophagitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985241"}
{"pmid": "20985242", "title": "A series of laryngeal injuries; with a description of endo-laryngeal burns.", "content": "A series of laryngeal injuries; with a description of endo-laryngeal burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985242"}
{"pmid": "20985244", "title": "Aero-otitis externa (a syndrome resulting from the use of earplugs in flight).", "content": "Aero-otitis externa (a syndrome resulting from the use of earplugs in flight).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985244"}
{"pmid": "20985243", "title": "Correlations between bone and air conduction acuity measurements over wide frequency ranges in different types of hearing impairments.", "content": "Correlations between bone and air conduction acuity measurements over wide frequency ranges in different types of hearing impairments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985243"}
{"pmid": "20985245", "title": "War otolaryngology.", "content": "War otolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985245"}
{"pmid": "20985246", "title": "Congenital preauricular sinuses.", "content": "Congenital preauricular sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985246"}
{"pmid": "20985251", "title": "Diagrammatic representation of the Rh blood types.", "content": "Diagrammatic representation of the Rh blood types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985251"}
{"pmid": "20985252", "title": "Acute infectious lymphocytosis.", "content": "Acute infectious lymphocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985252"}
{"pmid": "20985254", "title": "Large-scale routine examinations of stool for parasites.", "content": "Large-scale routine examinations of stool for parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985254"}
{"pmid": "20985253", "title": "Diabetes and other toxic effects following administration of alloxan into alimentary canal of rabbits.", "content": "Diabetes and other toxic effects following administration of alloxan into alimentary canal of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985253"}
{"pmid": "20985255", "title": "Diagnosis of Manson's schistosomiasis by biopsy of rectal tissue.", "content": "Diagnosis of Manson's schistosomiasis by biopsy of rectal tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985255"}
{"pmid": "20985256", "title": "A comparative study of the Kolmer complement-fixation test for syphilis with plasma and with serum.", "content": "A comparative study of the Kolmer complement-fixation test for syphilis with plasma and with serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985256"}
{"pmid": "20985257", "title": "Management of soldiers with glycosuria in a separation center.", "content": "Management of soldiers with glycosuria in a separation center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985257"}
{"pmid": "20985258", "title": "Spontaneous regression of metastatic sarcoma; report of case.", "content": "Spontaneous regression of metastatic sarcoma; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985258"}
{"pmid": "20985283", "title": "Dyspnea; fatigue; blueness. [Heart abnormity].", "content": "Dyspnea; fatigue; blueness. [Heart abnormity].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985283"}
{"pmid": "20985284", "title": "Swollen glands; enlarged abdomen. [Leukemic myelosis].", "content": "Swollen glands; enlarged abdomen. [Leukemic myelosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985284"}
{"pmid": "20985285", "title": "Intermittent vomiting. [Volvulus of intestine].", "content": "Intermittent vomiting. [Volvulus of intestine].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985285"}
{"pmid": "20985286", "title": "How parents hinder adolescents' adjustments to the opposite sex.", "content": "How parents hinder adolescents' adjustments to the opposite sex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985286"}
{"pmid": "20985287", "title": "SCREENING, eye examinations, and follow-up.", "content": "SCREENING, eye examinations, and follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985287"}
{"pmid": "20985288", "title": "Surgical treatment of intractable plantar warts.", "content": "Surgical treatment of intractable plantar warts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985288"}
{"pmid": "20985302", "title": "Tolerances of National Formulary tablets and capsules.", "content": "Tolerances of National Formulary tablets and capsules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985302"}
{"pmid": "20985312", "title": "The so-called waxy starches.", "content": "The so-called waxy starches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985312"}
{"pmid": "20985313", "title": "The economics of penicillin production.", "content": "The economics of penicillin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985313"}
{"pmid": "20985314", "title": "Measurement of the dielectric constant as a tool in the analysis of essential oils.", "content": "Measurement of the dielectric constant as a tool in the analysis of essential oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985314"}
{"pmid": "20985304", "title": "Oleyl alcohol.", "content": "Oleyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985304"}
{"pmid": "20985315", "title": "Effervescent granular preparations.", "content": "Effervescent granular preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985315"}
{"pmid": "20985305", "title": "Camphor spirit assay.", "content": "Camphor spirit assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985305"}
{"pmid": "20985316", "title": "Studies of modern synthetic emulgents; the disperse phase effects.", "content": "Studies of modern synthetic emulgents; the disperse phase effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985316"}
{"pmid": "20985307", "title": "TURPENTINE oil.", "content": "TURPENTINE oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985307"}
{"pmid": "20985303", "title": "Some of the pharmaceutical necessities of the new National Formulary.", "content": "Some of the pharmaceutical necessities of the new National Formulary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985303"}
{"pmid": "20985317", "title": "PROGRESS in East African totaquina and pyrethrum research.", "content": "PROGRESS in East African totaquina and pyrethrum research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985317"}
{"pmid": "20985318", "title": "Calamine.", "content": "Calamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985318"}
{"pmid": "20985308", "title": "Hydroxyl number of cetyl alcohol.", "content": "Hydroxyl number of cetyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985308"}
{"pmid": "20985319", "title": "Action of anti-perspirant creams on fabrics.", "content": "Action of anti-perspirant creams on fabrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985319"}
{"pmid": "20985306", "title": "Assay for camphor in camphor spirit.", "content": "Assay for camphor in camphor spirit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985306"}
{"pmid": "20985320", "title": "PENICILLIN preparations of the British Pharmacopoeia.", "content": "PENICILLIN preparations of the British Pharmacopoeia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985320"}
{"pmid": "20985321", "title": "Recent advances in our knowledge of the ergot alkaloids.", "content": "Recent advances in our knowledge of the ergot alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985321"}
{"pmid": "20985322", "title": "The need for systematic nomenclature; preparations for external use.", "content": "The need for systematic nomenclature; preparations for external use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985322"}
{"pmid": "20985323", "title": "[On the mechanism of the ultraparadoxal phase].", "content": "[On the mechanism of the ultraparadoxal phase].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985323"}
{"pmid": "20985325", "title": "[On functional superpositions in cortical dynamics].", "content": "[On functional superpositions in cortical dynamics].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985325"}
{"pmid": "20985324", "title": "[A study in the relative lability of the processes of higher nervous activity connected with individual analysers].", "content": "[A study in the relative lability of the processes of higher nervous activity connected with individual analysers].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985324"}
{"pmid": "20985326", "title": "[The effect of a short delay on the retarded conditioned reflex].", "content": "[The effect of a short delay on the retarded conditioned reflex].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985326"}
{"pmid": "20985327", "title": "[The effect of a short delay on the retarded conditioned reflex developed in another analyser].", "content": "[The effect of a short delay on the retarded conditioned reflex developed in another analyser].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985327"}
{"pmid": "20985328", "title": "[A comparative study of trace and delayed conditioned reflexes].", "content": "[A comparative study of trace and delayed conditioned reflexes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985328"}
{"pmid": "20985329", "title": "[The effect of magnitude of unconditioned stimulating on the delayed reflex].", "content": "[The effect of magnitude of unconditioned stimulating on the delayed reflex].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985329"}
{"pmid": "20985330", "title": "[Further contribution to the correlation between the values of the conditioned and unconditioned food reflexes].", "content": "[Further contribution to the correlation between the values of the conditioned and unconditioned food reflexes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985330"}
{"pmid": "20985331", "title": "[Dynamics in interrelations between conditioned and unconditioned reflexes].", "content": "[Dynamics in interrelations between conditioned and unconditioned reflexes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985331"}
{"pmid": "20985332", "title": "[On the depth of hypnotic inhibition in pauses upon prolonged application of a multinomial stereotype].", "content": "[On the depth of hypnotic inhibition in pauses upon prolonged application of a multinomial stereotype].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985332"}
{"pmid": "20985333", "title": "[The effect of the superstrong stimulus (a rattle) on the conditioned reflex activity of a dog belonging to the excitable type].", "content": "[The effect of the superstrong stimulus (a rattle) on the conditioned reflex activity of a dog belonging to the excitable type].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985333"}
{"pmid": "20985334", "title": "[On chronic application of external inhibitory stimulus].", "content": "[On chronic application of external inhibitory stimulus].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985334"}
{"pmid": "20985335", "title": "[Distortion of the course of salivation in some dogs].", "content": "[Distortion of the course of salivation in some dogs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985335"}
{"pmid": "20985336", "title": "[On the conditions contributing to a more precise differentiation].", "content": "[On the conditions contributing to a more precise differentiation].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985336"}
{"pmid": "20985337", "title": "[On the mechanism of differentiation of positive stimuli, according to the place of feeding].", "content": "[On the mechanism of differentiation of positive stimuli, according to the place of feeding].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985337"}
{"pmid": "20985338", "title": "[On the respiratory component of conditioned reflexes].", "content": "[On the respiratory component of conditioned reflexes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985338"}
{"pmid": "20985339", "title": "[Alterations of conditioned reflexes in old age].", "content": "[Alterations of conditioned reflexes in old age].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985339"}
{"pmid": "20985340", "title": "Mind and mechanism.", "content": "Mind and mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985340"}
{"pmid": "20985341", "title": "The time-error in auditory perception.", "content": "The time-error in auditory perception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985341"}
{"pmid": "20985342", "title": "The effect of type-size on accuracy of apprehension and speed of localizing words.", "content": "The effect of type-size on accuracy of apprehension and speed of localizing words.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985342"}
{"pmid": "20985343", "title": "Task-orientation vs. ego-orientation in learning and retention.", "content": "Task-orientation vs. ego-orientation in learning and retention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985343"}
{"pmid": "20985344", "title": "Significance of etiology in motor performance of deaf children with special reference to meningitis.", "content": "Significance of etiology in motor performance of deaf children with special reference to meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985344"}
{"pmid": "20985345", "title": "Role of vestibular nystagmus in the visual perception of a moving target in the dark.", "content": "Role of vestibular nystagmus in the visual perception of a moving target in the dark.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985345"}
{"pmid": "20985346", "title": "Minor studies from the psychological laboratory of Cornell University; Centrifugal swing effects in the human stylus maze.", "content": "Minor studies from the psychological laboratory of Cornell University; Centrifugal swing effects in the human stylus maze.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985346"}
{"pmid": "20985348", "title": "On the number of articles of psychological interest published in the different languages; 1936-1945.", "content": "On the number of articles of psychological interest published in the different languages; 1936-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985348"}
{"pmid": "20985347", "title": "The finger tromometer.", "content": "The finger tromometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985347"}
{"pmid": "20985349", "title": "Measurement of affective power in terms of ratios of partial epsilon 2s.", "content": "Measurement of affective power in terms of ratios of partial epsilon 2s.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985349"}
{"pmid": "20985351", "title": "Personality, a symposium; geneticism versus ego-structure in theories of personality.", "content": "Personality, a symposium; geneticism versus ego-structure in theories of personality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985351"}
{"pmid": "20985350", "title": "Classroom experiments on mental set.", "content": "Classroom experiments on mental set.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985350"}
{"pmid": "20985352", "title": "Selection for technical education.", "content": "Selection for technical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985352"}
{"pmid": "20985353", "title": "Attitudes of teachers and scholars towards co-education.", "content": "Attitudes of teachers and scholars towards co-education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985353"}
{"pmid": "20985354", "title": "The psychological guidance of parents in the upbringing of children.", "content": "The psychological guidance of parents in the upbringing of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985354"}
{"pmid": "20985355", "title": "Properties of learning curve under varied distributions of practice.", "content": "Properties of learning curve under varied distributions of practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985355"}
{"pmid": "20985356", "title": "The influence of simultaneous hunger and thirst drives upon the learning of two opposed spatial responses of the white rat.", "content": "The influence of simultaneous hunger and thirst drives upon the learning of two opposed spatial responses of the white rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985356"}
{"pmid": "20985357", "title": "Studies in spatial learning; place learning versus response learning.", "content": "Studies in spatial learning; place learning versus response learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985357"}
{"pmid": "20985358", "title": "Success and failure in serial learning; the Thorndike effect.", "content": "Success and failure in serial learning; the Thorndike effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985358"}
{"pmid": "20985359", "title": "The effect of changed polarity of set on decision time of affective judgments.", "content": "The effect of changed polarity of set on decision time of affective judgments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985359"}
{"pmid": "20985361", "title": "The learning and retention of concepts; the influence of the complexity of the stimuli.", "content": "The learning and retention of concepts; the influence of the complexity of the stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985361"}
{"pmid": "20985360", "title": "The effects of carbon monoxide on three types of performance, at simulated altitudes of 10,000 and 15,000 feet.", "content": "The effects of carbon monoxide on three types of performance, at simulated altitudes of 10,000 and 15,000 feet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985360"}
{"pmid": "20985363", "title": "The influence of belief and disbelief in ESP upon individual scoring levels.", "content": "The influence of belief and disbelief in ESP upon individual scoring levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985363"}
{"pmid": "20985362", "title": "Retroactive inhibition as a function of the relative serial positions of the original and interpolated items.", "content": "Retroactive inhibition as a function of the relative serial positions of the original and interpolated items.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985362"}
{"pmid": "20985364", "title": "Observations on tsutsugamushi disease (scrub typhus) in Assam and Burma; preliminary report.", "content": "Observations on tsutsugamushi disease (scrub typhus) in Assam and Burma; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985364"}
{"pmid": "20985366", "title": "New Guinea field tests of uniforms impregnated with miticides to develop laundry-resistant clothing treatments for preventing scrub typhus.", "content": "New Guinea field tests of uniforms impregnated with miticides to develop laundry-resistant clothing treatments for preventing scrub typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985366"}
{"pmid": "20985365", "title": "Tests against chiggers in New Guinea to develop a practical field method for impregnating uniforms with dimethyl phthalate for scrub typhus prevention.", "content": "Tests against chiggers in New Guinea to develop a practical field method for impregnating uniforms with dimethyl phthalate for scrub typhus prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985365"}
{"pmid": "20985367", "title": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; clinical syndrome, morbidity, mortality, seasonal incidence.", "content": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; clinical syndrome, morbidity, mortality, seasonal incidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985367"}
{"pmid": "20985368", "title": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; epidemic pattern; outbreaks with distinctive features.", "content": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; epidemic pattern; outbreaks with distinctive features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985368"}
{"pmid": "20985370", "title": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; rank and grade.", "content": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; rank and grade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985370"}
{"pmid": "20985369", "title": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; age.", "content": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985369"}
{"pmid": "20985371", "title": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; headquarters, service and combat troops.", "content": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; headquarters, service and combat troops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985371"}
{"pmid": "20985372", "title": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; the assimilation of replacements, 1943-1944 season.", "content": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; the assimilation of replacements, 1943-1944 season.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985372"}
{"pmid": "20985373", "title": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; seasoning and incidence, 1944-45.", "content": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; selection among American troops; seasoning and incidence, 1944-45.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985373"}
{"pmid": "20985374", "title": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; relation between vaccine jaundice and infectious hepatitis.", "content": "Epidemiological field studies of infectious hepatitis in the Mediterranean Theater of Operations; relation between vaccine jaundice and infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985374"}
{"pmid": "20985375", "title": "Epidemic infectious hepatitis in a small Iowa community.", "content": "Epidemic infectious hepatitis in a small Iowa community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985375"}
{"pmid": "20985376", "title": "Studies on imported malarias; the infectivity of malarias of foreign origin to anophelines of the southern United States.", "content": "Studies on imported malarias; the infectivity of malarias of foreign origin to anophelines of the southern United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985376"}
{"pmid": "20985377", "title": "Nutrition and national health.", "content": "Nutrition and national health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985377"}
{"pmid": "20985380", "title": "A national health service.", "content": "A national health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985380"}
{"pmid": "20985383", "title": "The problem of tuberculosis; prevention and treatment.", "content": "The problem of tuberculosis; prevention and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985383"}
{"pmid": "20985379", "title": "Rehabilitation and resettlement (RHBN).", "content": "Rehabilitation and resettlement (RHBN).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985379"}
{"pmid": "20985381", "title": "Social medicine.", "content": "Social medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985381"}
{"pmid": "20985378", "title": "The war and medical progress.", "content": "The war and medical progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985378"}
{"pmid": "20985385", "title": "Future developments in the field of mental health.", "content": "Future developments in the field of mental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985385"}
{"pmid": "20985382", "title": "Maternity services in England and Wales.", "content": "Maternity services in England and Wales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985382"}
{"pmid": "20985384", "title": "Rheumatism, a great social plague.", "content": "Rheumatism, a great social plague.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985384"}
{"pmid": "20985388", "title": "The almoner as a medico-social worker.", "content": "The almoner as a medico-social worker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985388"}
{"pmid": "20985386", "title": "Nursing.", "content": "Nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985386"}
{"pmid": "20985387", "title": "The health visitor.", "content": "The health visitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985387"}
{"pmid": "20985395", "title": "Emergency medical service.", "content": "Emergency medical service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985395"}
{"pmid": "20985391", "title": "Family allowances and the provision of school meals.", "content": "Family allowances and the provision of school meals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985391"}
{"pmid": "20985389", "title": "Health and welfare in the Civil Service.", "content": "Health and welfare in the Civil Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985389"}
{"pmid": "20985390", "title": "The day nursery.", "content": "The day nursery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985390"}
{"pmid": "20985392", "title": "Care of the eyes in home and factory.", "content": "Care of the eyes in home and factory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985392"}
{"pmid": "20985407", "title": "Modern methods in the treatment of burns.", "content": "Modern methods in the treatment of burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985407"}
{"pmid": "20985394", "title": "Medical and nursing services in factories.", "content": "Medical and nursing services in factories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985394"}
{"pmid": "20985408", "title": "Health and hygiene in the Colonial Empire.", "content": "Health and hygiene in the Colonial Empire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985408"}
{"pmid": "20985409", "title": "Uses of radiology in medicine.", "content": "Uses of radiology in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985409"}
{"pmid": "20985393", "title": "Compensation for industrial injury.", "content": "Compensation for industrial injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985393"}
{"pmid": "20985396", "title": "Dental health.", "content": "Dental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985396"}
{"pmid": "20985397", "title": "The juvenile court and child protection.", "content": "The juvenile court and child protection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985397"}
{"pmid": "20985410", "title": "Variations in, and the effect of weather conditions on, the growth of children.", "content": "Variations in, and the effect of weather conditions on, the growth of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985410"}
{"pmid": "20985401", "title": "Medical services in the United States.", "content": "Medical services in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985401"}
{"pmid": "20985398", "title": "Settling down In Civvy Street.", "content": "Settling down In Civvy Street.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985398"}
{"pmid": "20985411", "title": "WAR, migration, and the demographic decline of France.", "content": "WAR, migration, and the demographic decline of France.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985411"}
{"pmid": "20985402", "title": "Food and health problems in Australia.", "content": "Food and health problems in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985402"}
{"pmid": "20985412", "title": "BCG vaccination against tuberculosis.", "content": "BCG vaccination against tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985412"}
{"pmid": "20985413", "title": "Experience with BCB vaccine in the control of tuberculosis among North American Indians.", "content": "Experience with BCB vaccine in the control of tuberculosis among North American Indians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985413"}
{"pmid": "20985399", "title": "Treatment and resettlement of war psycho-neurosis.", "content": "Treatment and resettlement of war psycho-neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985399"}
{"pmid": "20985414", "title": "LONGEVITY OF THE American people in 1944.", "content": "LONGEVITY OF THE American people in 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985414"}
{"pmid": "20985400", "title": "The public health services of London.", "content": "The public health services of London.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985400"}
{"pmid": "20985415", "title": "INTERMARRIAGE among national groups increasing.", "content": "INTERMARRIAGE among national groups increasing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985415"}
{"pmid": "20985416", "title": "MEASURING family responsibility.", "content": "MEASURING family responsibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985416"}
{"pmid": "20985404", "title": "Public health and social welfare in the Union of South Africa.", "content": "Public health and social welfare in the Union of South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985404"}
{"pmid": "20985417", "title": "SMALLPOX at its lowest ebb in 1945.", "content": "SMALLPOX at its lowest ebb in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985417"}
{"pmid": "20985403", "title": "Health and social welfare in New Zealand.", "content": "Health and social welfare in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985403"}
{"pmid": "20985405", "title": "Medical services in Southern Rhodesia.", "content": "Medical services in Southern Rhodesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985405"}
{"pmid": "20985418", "title": "Points regarding the time factor in roentgen irradiation with divided dosage.", "content": "Points regarding the time factor in roentgen irradiation with divided dosage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985418"}
{"pmid": "20985406", "title": "Health services in British colonial territories in Africa.", "content": "Health services in British colonial territories in Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985406"}
{"pmid": "20985419", "title": "A new type of wave motion and its importance in solar physics.", "content": "A new type of wave motion and its importance in solar physics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985419"}
{"pmid": "20985420", "title": "An instrument for calculating roentgen ray doses from condenser chamber readings.", "content": "An instrument for calculating roentgen ray doses from condenser chamber readings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985420"}
{"pmid": "20985421", "title": "The mineral metabolism in the dental hard tissues.", "content": "The mineral metabolism in the dental hard tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985421"}
{"pmid": "20985422", "title": "On retrocardiac pulmo-pleural demarcation lines and their diagnostic significance.", "content": "On retrocardiac pulmo-pleural demarcation lines and their diagnostic significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985422"}
{"pmid": "20985423", "title": "Radiation measurements on a continuously evacuated roentgen tube for 400 kV.", "content": "Radiation measurements on a continuously evacuated roentgen tube for 400 kV.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985423"}
{"pmid": "20985425", "title": "The action of roentgen rays on the enzyme catalase.", "content": "The action of roentgen rays on the enzyme catalase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985425"}
{"pmid": "20985424", "title": "Influence of roentgen rays on isolated cell nuclei.", "content": "Influence of roentgen rays on isolated cell nuclei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985424"}
{"pmid": "20985426", "title": "3 cases of skeletal changes round the knee joint in paratyphoid fever in infants.", "content": "3 cases of skeletal changes round the knee joint in paratyphoid fever in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985426"}
{"pmid": "20985427", "title": "The origin of albina and xantha mutations in barley.", "content": "The origin of albina and xantha mutations in barley.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985427"}
{"pmid": "20985428", "title": "The connexion between roentgen ray risks for workers and changes in their blood pictures.", "content": "The connexion between roentgen ray risks for workers and changes in their blood pictures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985428"}
{"pmid": "20985429", "title": "The effect of roentgen rays and ultraviolet radiation on the permeability of yeast.", "content": "The effect of roentgen rays and ultraviolet radiation on the permeability of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985429"}
{"pmid": "20985430", "title": "Further experience with radiotherapy in cancer of the corpus of the uterus.", "content": "Further experience with radiotherapy in cancer of the corpus of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985430"}
{"pmid": "20985431", "title": "The registration of the movements of the heart with Geiger-Müller counters and synchronous electrocardiography.", "content": "The registration of the movements of the heart with Geiger-Müller counters and synchronous electrocardiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985431"}
{"pmid": "20985432", "title": "Results of treatment with radiotherapy in carcinoma of the prostate.", "content": "Results of treatment with radiotherapy in carcinoma of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985432"}
{"pmid": "20985433", "title": "A case of cancer of the oesophagus, alive and free from evidence of tumour 6 years after roentgen treatment.", "content": "A case of cancer of the oesophagus, alive and free from evidence of tumour 6 years after roentgen treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985433"}
{"pmid": "20985434", "title": "Results of radiotherapy of epibulbar tumors at Radiumhemmet, Stockholm, 1920-1940.", "content": "Results of radiotherapy of epibulbar tumors at Radiumhemmet, Stockholm, 1920-1940.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985434"}
{"pmid": "20985437", "title": "Two mechanical devices for reducing the risk of radiation exposure during certain types of roentgen examinations.", "content": "Two mechanical devices for reducing the risk of radiation exposure during certain types of roentgen examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985437"}
{"pmid": "20985438", "title": "Intravascular and extravascular pressure in Valsalva's experiment.", "content": "Intravascular and extravascular pressure in Valsalva's experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985438"}
{"pmid": "20985440", "title": "Fractures in the elbow with particular regard to the distal humerus end.", "content": "Fractures in the elbow with particular regard to the distal humerus end.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985440"}
{"pmid": "20985441", "title": "Blood changes in radiologic work.", "content": "Blood changes in radiologic work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985441"}
{"pmid": "20985443", "title": "On the gamma-radiation from polonium.", "content": "On the gamma-radiation from polonium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985443"}
{"pmid": "20985444", "title": "A tri-electrode standard airionisation chamber for roentgen ray measurements in r-units.", "content": "A tri-electrode standard airionisation chamber for roentgen ray measurements in r-units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985444"}
{"pmid": "20985445", "title": "A contribution to the roentgen diagnostics of limited esophagitis.", "content": "A contribution to the roentgen diagnostics of limited esophagitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985445"}
{"pmid": "20985446", "title": "Malignant melanomata; introductory remarks to discussion on melanoma.", "content": "Malignant melanomata; introductory remarks to discussion on melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985446"}
{"pmid": "20985447", "title": "Malignant melanomata; some observations on their pathology.", "content": "Malignant melanomata; some observations on their pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985447"}
{"pmid": "20985448", "title": "Radiological treatment of malignant melanoma.", "content": "Radiological treatment of malignant melanoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985448"}
{"pmid": "20985449", "title": "The pigmented tumours of the skin.", "content": "The pigmented tumours of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985449"}
{"pmid": "20985450", "title": "A direct-reading x-ray intensity comparator; its radiological and physical applications.", "content": "A direct-reading x-ray intensity comparator; its radiological and physical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985450"}
{"pmid": "20985451", "title": "Subacute volvulus of the terminal ileum (case report).", "content": "Subacute volvulus of the terminal ileum (case report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985451"}
{"pmid": "20985452", "title": "Anaerobic cellulitis due to Actinomyces, associated with gas production.", "content": "Anaerobic cellulitis due to Actinomyces, associated with gas production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985452"}
{"pmid": "20985453", "title": "Some observations on radiography of the ear, nose, and throat.", "content": "Some observations on radiography of the ear, nose, and throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985453"}
{"pmid": "20985454", "title": "THE radiographer in the radiotherapeutic department.", "content": "THE radiographer in the radiotherapeutic department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985454"}
{"pmid": "20985455", "title": "On the treatment of perforated gastric and duodenal ulcer.", "content": "On the treatment of perforated gastric and duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985455"}
{"pmid": "20985457", "title": "Unilateral double ureter with partly vaginal, partly normal outlet.", "content": "Unilateral double ureter with partly vaginal, partly normal outlet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985457"}
{"pmid": "20985456", "title": "Arthrosis in the knee after meniscectomy.", "content": "Arthrosis in the knee after meniscectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985456"}
{"pmid": "20985459", "title": "Rupture of kidney tumours and hydronephroses.", "content": "Rupture of kidney tumours and hydronephroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985459"}
{"pmid": "20985460", "title": "Displacement of the kidney consequent upon spontaneous perirenal hematoma.", "content": "Displacement of the kidney consequent upon spontaneous perirenal hematoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985460"}
{"pmid": "20985461", "title": "Ectopic course of the ureter attended with hydronephrosis.", "content": "Ectopic course of the ureter attended with hydronephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985461"}
{"pmid": "20985462", "title": "Elbow injuries of javelin-throwers.", "content": "Elbow injuries of javelin-throwers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985462"}
{"pmid": "20985501", "title": "Physical medicine in Britain.", "content": "Physical medicine in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985501"}
{"pmid": "20985502", "title": "A report on the program of training and research in physics and technology conducted at the Massachusetts Institute of Technology.", "content": "A report on the program of training and research in physics and technology conducted at the Massachusetts Institute of Technology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985502"}
{"pmid": "20985503", "title": "Radiology and physiotherapy; their connection in some foot ailments.", "content": "Radiology and physiotherapy; their connection in some foot ailments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985503"}
{"pmid": "20985504", "title": "Anterior poliomyelitis; from a patient's point of view.", "content": "Anterior poliomyelitis; from a patient's point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985504"}
{"pmid": "20985505", "title": "Physiotherapy for chest conditions.", "content": "Physiotherapy for chest conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985505"}
{"pmid": "20985511", "title": "CLINICAL usefulness of desicol.", "content": "CLINICAL usefulness of desicol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985511"}
{"pmid": "20985512", "title": "MANAGEMENT of motion sickness.", "content": "MANAGEMENT of motion sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985512"}
{"pmid": "20985506", "title": "A functional training center.", "content": "A functional training center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985506"}
{"pmid": "20985513", "title": "Spontaneous pneumothorax.", "content": "Spontaneous pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985513"}
{"pmid": "20985514", "title": "Nutrition in tuberculosis; a resume of some recent contributions.", "content": "Nutrition in tuberculosis; a resume of some recent contributions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985514"}
{"pmid": "20985515", "title": "The future of the sanatorium.", "content": "The future of the sanatorium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985515"}
{"pmid": "20985517", "title": "Body temperature and respiration rate, and their relation to adaptability in sheep.", "content": "Body temperature and respiration rate, and their relation to adaptability in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985517"}
{"pmid": "20985516", "title": "The transdermal (or transcutaneous) tuberculin test (Corper) with autolytic tuberculin in clinical tuberculosis.", "content": "The transdermal (or transcutaneous) tuberculin test (Corper) with autolytic tuberculin in clinical tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985516"}
{"pmid": "20985507", "title": "The Rehabilitation Center of San Francisco, Inc.", "content": "The Rehabilitation Center of San Francisco, Inc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985507"}
{"pmid": "20985518", "title": "Inheritance of skin folds of sheep.", "content": "Inheritance of skin folds of sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985518"}
{"pmid": "20985519", "title": "Heritability of face covering and neck folds in range Rambouillet lambs as evaluated by scoring.", "content": "Heritability of face covering and neck folds in range Rambouillet lambs as evaluated by scoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985519"}
{"pmid": "20985520", "title": "The influence of high-protein and low-protein-high-starch diets on blood glucose and acetone bodies of pregnant ewes.", "content": "The influence of high-protein and low-protein-high-starch diets on blood glucose and acetone bodies of pregnant ewes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985520"}
{"pmid": "20985508", "title": "Hospital service in the United States.", "content": "Hospital service in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985508"}
{"pmid": "20985521", "title": "The value of shark meal in swine rations.", "content": "The value of shark meal in swine rations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985521"}
{"pmid": "20985522", "title": "Biotin deficiency syndrome in pigs fed desicated egg white.", "content": "Biotin deficiency syndrome in pigs fed desicated egg white.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985522"}
{"pmid": "20985526", "title": "The eradication of tuberculosis in cattle.", "content": "The eradication of tuberculosis in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985526"}
{"pmid": "20985527", "title": "Malignant catarrhal fever.", "content": "Malignant catarrhal fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985527"}
{"pmid": "20985528", "title": "Use of D.D.T. against sheep ticks, Ixodes ricinus L.", "content": "Use of D.D.T. against sheep ticks, Ixodes ricinus L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985528"}
{"pmid": "20985529", "title": "Some observations on the blood leucocyte picture in bovines during reaction to the intradermal tuberculin test.", "content": "Some observations on the blood leucocyte picture in bovines during reaction to the intradermal tuberculin test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985529"}
{"pmid": "20985530", "title": "The toxicity of sodium chloride for fowls.", "content": "The toxicity of sodium chloride for fowls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985530"}
{"pmid": "20985531", "title": "Further observations on the incidence of parasitic aneurysm in the horse.", "content": "Further observations on the incidence of parasitic aneurysm in the horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985531"}
{"pmid": "20985533", "title": "CONTROL of infectious animal diseases in the South-West Pacific area.", "content": "CONTROL of infectious animal diseases in the South-West Pacific area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985533"}
{"pmid": "20985532", "title": "Treatment of sarcoptic mange in the dog using hexachlorobenzene.", "content": "Treatment of sarcoptic mange in the dog using hexachlorobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985532"}
{"pmid": "20985534", "title": "The survival of Corynebacterium pyogenes in discharges from the udder and the uterus of the cow.", "content": "The survival of Corynebacterium pyogenes in discharges from the udder and the uterus of the cow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985534"}
{"pmid": "20985535", "title": "A malignant vaginal neoplasm in a cow cured by stilboestrol implantation.", "content": "A malignant vaginal neoplasm in a cow cured by stilboestrol implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985535"}
{"pmid": "20985536", "title": "The pathogenicity to cattle of Trypanosoma vivax.", "content": "The pathogenicity to cattle of Trypanosoma vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985536"}
{"pmid": "20985537", "title": "Beta haemolytic streptococcus infection in dogs.", "content": "Beta haemolytic streptococcus infection in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985537"}
{"pmid": "20985538", "title": "Clinical report on a glandular disease occurring in epidemic form amongst dogs.", "content": "Clinical report on a glandular disease occurring in epidemic form amongst dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985538"}
{"pmid": "20985539", "title": "PASTEURIZATION of milk.", "content": "PASTEURIZATION of milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985539"}
{"pmid": "20985540", "title": "A field case of nutritional encephalomalacia in chicks.", "content": "A field case of nutritional encephalomalacia in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985540"}
{"pmid": "20985542", "title": "Fatal malignant melanomata in a grey cart gelding.", "content": "Fatal malignant melanomata in a grey cart gelding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985542"}
{"pmid": "20985541", "title": "The benefits of animal experiments to man and beast.", "content": "The benefits of animal experiments to man and beast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985541"}
{"pmid": "20985543", "title": "Luxation of the patella.", "content": "Luxation of the patella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985543"}
{"pmid": "20985544", "title": "Scours in buffalo calves.", "content": "Scours in buffalo calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985544"}
{"pmid": "20985545", "title": "A preliminary note on Salmonella dublin infection in adult cattle.", "content": "A preliminary note on Salmonella dublin infection in adult cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985545"}
{"pmid": "20985546", "title": "Caesarean operation on a cow.", "content": "Caesarean operation on a cow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985546"}
{"pmid": "20985547", "title": "Some canine and feline disease problems.", "content": "Some canine and feline disease problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985547"}
{"pmid": "20985548", "title": "Bovine infertility associated with staphylococcal infection.", "content": "Bovine infertility associated with staphylococcal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985548"}
{"pmid": "20985549", "title": "Removal of nine-inch knitting needle from oesophagus and stomach of cat.", "content": "Removal of nine-inch knitting needle from oesophagus and stomach of cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985549"}
{"pmid": "20985550", "title": "Pelomyxa carolinensis Wilson; general observation on the Illinois stock.", "content": "Pelomyxa carolinensis Wilson; general observation on the Illinois stock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985550"}
{"pmid": "20985551", "title": "Conjugation in Paramecium bursaria; conjugation of three animals.", "content": "Conjugation in Paramecium bursaria; conjugation of three animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985551"}
{"pmid": "20985552", "title": "The slime glands and thread cells of the hagfish, Polistrotrema stouti.", "content": "The slime glands and thread cells of the hagfish, Polistrotrema stouti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985552"}
{"pmid": "20985555", "title": "The health and customs of the Miskito Indians of northern Nicaragua: interrelationships in a medical program.", "content": "The health and customs of the Miskito Indians of northern Nicaragua: interrelationships in a medical program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985555"}
{"pmid": "20985556", "title": "Military government in Saipan and Tinian.", "content": "Military government in Saipan and Tinian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985556"}
{"pmid": "20985563", "title": "Variation within strains of clover nodule bacteria in the size of nodule produced and in the effectivity of the symbiosis.", "content": "Variation within strains of clover nodule bacteria in the size of nodule produced and in the effectivity of the symbiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985563"}
{"pmid": "20985564", "title": "An additional Shigella paradysenteriae serotype.", "content": "An additional Shigella paradysenteriae serotype.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985564"}
{"pmid": "20985565", "title": "The effect of sulfonamides on the action of penicillin.", "content": "The effect of sulfonamides on the action of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985565"}
{"pmid": "20985559", "title": "Cain and Abel; human sacrifice.", "content": "Cain and Abel; human sacrifice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985559"}
{"pmid": "20985566", "title": "Influence or incubation temperatures on differential tests of coliform bacteria.", "content": "Influence or incubation temperatures on differential tests of coliform bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985566"}
{"pmid": "20985567", "title": "Microbiological aspects of penicillin; production of penicillin in submerged cultures of Penicillium notatum.", "content": "Microbiological aspects of penicillin; production of penicillin in submerged cultures of Penicillium notatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985567"}
{"pmid": "20985557", "title": "Archaeological notes from Northern Nigeria.", "content": "Archaeological notes from Northern Nigeria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985557"}
{"pmid": "20985568", "title": "Biologic changes in sulfonamide-resistant Mycobacterium ranae.", "content": "Biologic changes in sulfonamide-resistant Mycobacterium ranae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985568"}
{"pmid": "20985570", "title": "External otitis, with additional studies on the genus Pseudomonas.", "content": "External otitis, with additional studies on the genus Pseudomonas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985570"}
{"pmid": "20985569", "title": "Ultrasonic disintegration as a method of extracting bacterial enzymes.", "content": "Ultrasonic disintegration as a method of extracting bacterial enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985569"}
{"pmid": "20985571", "title": "Growth inhibition of strain H37 of the human tubercle bacillus by 4-n-alkyl-resorcinols in the depth of a liquid, synthetic, nonprotein culture medium.", "content": "Growth inhibition of strain H37 of the human tubercle bacillus by 4-n-alkyl-resorcinols in the depth of a liquid, synthetic, nonprotein culture medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985571"}
{"pmid": "20985572", "title": "The cecal flora of white rats on a purified diet and its modification by succinylsulfathiazole.", "content": "The cecal flora of white rats on a purified diet and its modification by succinylsulfathiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985572"}
{"pmid": "20985558", "title": "Anthropological research; its strategy and tactics.", "content": "Anthropological research; its strategy and tactics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985558"}
{"pmid": "20985573", "title": "The segregation of antigens in a bacterial culture by an undescribed form of variation.", "content": "The segregation of antigens in a bacterial culture by an undescribed form of variation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985573"}
{"pmid": "20985574", "title": "Glass bacteriological filters arranged for positive pressure.", "content": "Glass bacteriological filters arranged for positive pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985574"}
{"pmid": "20985575", "title": "Effect of Staphylococcus aureus extracts on various bacteria.", "content": "Effect of Staphylococcus aureus extracts on various bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985575"}
{"pmid": "20985576", "title": "Atypical acid-fast microorganisms; desoxyribonucleic acid content.", "content": "Atypical acid-fast microorganisms; desoxyribonucleic acid content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985576"}
{"pmid": "20985577", "title": "The influence of heavy water on the growth, morphology, and fermentation reactions of Eberthella typhosa.", "content": "The influence of heavy water on the growth, morphology, and fermentation reactions of Eberthella typhosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985577"}
{"pmid": "20985578", "title": "Survival for fourteen years of agar slant cultures of Escherichia coli-mutabile without loss of important characters.", "content": "Survival for fourteen years of agar slant cultures of Escherichia coli-mutabile without loss of important characters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985578"}
{"pmid": "20985579", "title": "The substitution of thiamine for the labile fraction of red blood cell extract in the growth of Bacterium tularense.", "content": "The substitution of thiamine for the labile fraction of red blood cell extract in the growth of Bacterium tularense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985579"}
{"pmid": "20985580", "title": "A readily prepared medium for the cultivation of the lactobacilli.", "content": "A readily prepared medium for the cultivation of the lactobacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985580"}
{"pmid": "20985581", "title": "A new Salmonella type; Salmonella gatuni.", "content": "A new Salmonella type; Salmonella gatuni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985581"}
{"pmid": "20985582", "title": "Cholera in Chungking in 1945; use of streptomycin.", "content": "Cholera in Chungking in 1945; use of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985582"}
{"pmid": "20985584", "title": "On oblique growth of trees under the action of winds.", "content": "On oblique growth of trees under the action of winds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985584"}
{"pmid": "20985585", "title": "Further contributions to a probabilistic interpretation of the mathematical biophysics of the central nervous system.", "content": "Further contributions to a probabilistic interpretation of the mathematical biophysics of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985585"}
{"pmid": "20985586", "title": "A note on the excitation of nerve pathways.", "content": "A note on the excitation of nerve pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985586"}
{"pmid": "20985587", "title": "CANCER facilities and services; a report from the National Advisory Cancer Council.", "content": "CANCER facilities and services; a report from the National Advisory Cancer Council.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985587"}
{"pmid": "20985588", "title": "Treatment of coronary thrombosis.", "content": "Treatment of coronary thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985588"}
{"pmid": "20985589", "title": "SIMPLE office treatment of ulcers and eczemas of the leg with combination (contura plus pressoplast) pressure bandages.", "content": "SIMPLE office treatment of ulcers and eczemas of the leg with combination (contura plus pressoplast) pressure bandages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985589"}
{"pmid": "20985590", "title": "Hexitol anhydrides; synthesis and structure of arlitan, the 1,4-monoanhydride of sorbitol.", "content": "Hexitol anhydrides; synthesis and structure of arlitan, the 1,4-monoanhydride of sorbitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985590"}
{"pmid": "20985591", "title": "Hexitol anhydrides; the structure of isosorbide, a crystalline dianhydrosorbitol.", "content": "Hexitol anhydrides; the structure of isosorbide, a crystalline dianhydrosorbitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985591"}
{"pmid": "20985592", "title": "Hexitol anhydrides; the structures of the anhydromannitols of Brigl and Grüner; the structure of isomannide.", "content": "Hexitol anhydrides; the structures of the anhydromannitols of Brigl and Grüner; the structure of isomannide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985592"}
{"pmid": "20985593", "title": "Hexitol anhydrides; the structure of the 2,5-anhydromannitol of Brigl and Grüner (2,5-anhydrosorbitol).", "content": "Hexitol anhydrides; the structure of the 2,5-anhydromannitol of Brigl and Grüner (2,5-anhydrosorbitol).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985593"}
{"pmid": "20985594", "title": "Hexitol anhydrides; the preparation and proof of structure of isomannide.", "content": "Hexitol anhydrides; the preparation and proof of structure of isomannide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985594"}
{"pmid": "20985595", "title": "Hexitol anhydrides; 1,4,3,6-dianhydro-L-iditol and the structures of isomannide and isosorbide.", "content": "Hexitol anhydrides; 1,4,3,6-dianhydro-L-iditol and the structures of isomannide and isosorbide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985595"}
{"pmid": "20985596", "title": "Arylaminoheterocycles; arsenicals of anilinopyrimidines.", "content": "Arylaminoheterocycles; arsenicals of anilinopyrimidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985596"}
{"pmid": "20985597", "title": "p-Aminobenzoates of piperidino- and morpholinomethylnaphthols.", "content": "p-Aminobenzoates of piperidino- and morpholinomethylnaphthols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985597"}
{"pmid": "20985598", "title": "Quinaldil, quinaldoin and diquinolylhydantoin.", "content": "Quinaldil, quinaldoin and diquinolylhydantoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985598"}
{"pmid": "20985599", "title": "Group and bond refractions in organosilicon liquids.", "content": "Group and bond refractions in organosilicon liquids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985599"}
{"pmid": "20985600", "title": "The ionization constant of acetic acid in 50 per cent glycerol-water solution from 0 to 90 degrees.", "content": "The ionization constant of acetic acid in 50 per cent glycerol-water solution from 0 to 90 degrees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985600"}
{"pmid": "20985601", "title": "Mechanism of the sulfonation of aromatic amines; sulfonation with fuming sulfuric acid.", "content": "Mechanism of the sulfonation of aromatic amines; sulfonation with fuming sulfuric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985601"}
{"pmid": "20985602", "title": "Some isomeric (methoxy)-(2,5-dimethylpyrryl-1)-quinolines.", "content": "Some isomeric (methoxy)-(2,5-dimethylpyrryl-1)-quinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985602"}
{"pmid": "20985603", "title": "Some quinolines patterned as open models of a modified atebrin.", "content": "Some quinolines patterned as open models of a modified atebrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985603"}
{"pmid": "20985604", "title": "8-Amino-6-quinolyl methyl sulfone.", "content": "8-Amino-6-quinolyl methyl sulfone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985604"}
{"pmid": "20985606", "title": "The synthesis of 3-alkyl-4-methylquinolines.", "content": "The synthesis of 3-alkyl-4-methylquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985606"}
{"pmid": "20985605", "title": "Chlorophenyl carbamates of methyl cellulose.", "content": "Chlorophenyl carbamates of methyl cellulose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985605"}
{"pmid": "20985607", "title": "Addition compounds of sulfur dioxide with pyridine and the picolines.", "content": "Addition compounds of sulfur dioxide with pyridine and the picolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985607"}
{"pmid": "20985608", "title": "Equilibria in saturated solutions; the ternary systems CaCl2-MgCl2-H2O, CaCl2-KCl-H2O, and MgCl2-KCl-H2O at 35 degrees.", "content": "Equilibria in saturated solutions; the ternary systems CaCl2-MgCl2-H2O, CaCl2-KCl-H2O, and MgCl2-KCl-H2O at 35 degrees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985608"}
{"pmid": "20985609", "title": "Dipole moment and resonance in vinyl sulfide and six unsaturated chlorohydrocarbons.", "content": "Dipole moment and resonance in vinyl sulfide and six unsaturated chlorohydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985609"}
{"pmid": "20985610", "title": "Synthesis of arylpropylamines; from allyl chloride.", "content": "Synthesis of arylpropylamines; from allyl chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985610"}
{"pmid": "20985611", "title": "A polymer reaction product of tyrosine and formaldehyde.", "content": "A polymer reaction product of tyrosine and formaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985611"}
{"pmid": "20985612", "title": "The acylation of polyuronides with formamide as a dispersing agent.", "content": "The acylation of polyuronides with formamide as a dispersing agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985612"}
{"pmid": "20985613", "title": "The chlorination of starch with phosphorus pentachloride.", "content": "The chlorination of starch with phosphorus pentachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985613"}
{"pmid": "20985614", "title": "Action of sulfating agents on proteins and model substances; concentrated sulfuric acid.", "content": "Action of sulfating agents on proteins and model substances; concentrated sulfuric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985614"}
{"pmid": "20985615", "title": "Action of sulfating agents on proteins and model substances; pyridine-chlorosulfonic acid.", "content": "Action of sulfating agents on proteins and model substances; pyridine-chlorosulfonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985615"}
{"pmid": "20985616", "title": "Substituted sulfaquinoxalines; the isolation and synthesis of 3-hydroxy-2-sulfanilamidoquinoxaline and of related quinoxalines.", "content": "Substituted sulfaquinoxalines; the isolation and synthesis of 3-hydroxy-2-sulfanilamidoquinoxaline and of related quinoxalines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985616"}
{"pmid": "20985617", "title": "Studies in chemotherapy; antimalarials; the synthesis of substituted metanilamides and related compounds.", "content": "Studies in chemotherapy; antimalarials; the synthesis of substituted metanilamides and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985617"}
{"pmid": "20985619", "title": "Piperidine derivatives; C-alkylation of l-benzoyl-3-carbethoxy-4-piperidone; synthesis of ethyl 3-ethyl-4-piperidylacetate (d1-ethyl cincholoiponate).", "content": "Piperidine derivatives; C-alkylation of l-benzoyl-3-carbethoxy-4-piperidone; synthesis of ethyl 3-ethyl-4-piperidylacetate (d1-ethyl cincholoiponate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985619"}
{"pmid": "20985618", "title": "Piperidine derivatives; the preparation of l-benzoyl-3-carbethoxy-4-piperidone; a synthesis of guvacine.", "content": "Piperidine derivatives; the preparation of l-benzoyl-3-carbethoxy-4-piperidone; a synthesis of guvacine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985618"}
{"pmid": "20985620", "title": "Dielectric constants of the methanol-water system from 5 to 55 degrees.", "content": "Dielectric constants of the methanol-water system from 5 to 55 degrees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985620"}
{"pmid": "20985621", "title": "The heat capacity, vapor pressure, heats of fusion and vaporization of cyclopropane; entropy and density of the gas.", "content": "The heat capacity, vapor pressure, heats of fusion and vaporization of cyclopropane; entropy and density of the gas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985621"}
{"pmid": "20985622", "title": "Organosilicon compounds; Beta-eliminations involving silicon.", "content": "Organosilicon compounds; Beta-eliminations involving silicon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985622"}
{"pmid": "20985623", "title": "The preparation and polymerization of four isomeric dimethylstyrenes.", "content": "The preparation and polymerization of four isomeric dimethylstyrenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985623"}
{"pmid": "20985624", "title": "The preparation and polymerization of some alkyl styrenes.", "content": "The preparation and polymerization of some alkyl styrenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985624"}
{"pmid": "20985625", "title": "Further studies on steric deformation.", "content": "Further studies on steric deformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985625"}
{"pmid": "20985626", "title": "The complexes of fatty acids with amylose.", "content": "The complexes of fatty acids with amylose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985626"}
{"pmid": "20985627", "title": "Some quaternary ammonium salts of heterocyclic bases.", "content": "Some quaternary ammonium salts of heterocyclic bases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985627"}
{"pmid": "20985628", "title": "Benzyl heptaacetyl-beta-lactoside.", "content": "Benzyl heptaacetyl-beta-lactoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985628"}
{"pmid": "20985629", "title": "Investigations of amino acids, peptides, and proteins; the determination of methionine in protein hydrolysates with Lactobacillus fermenti 36.", "content": "Investigations of amino acids, peptides, and proteins; the determination of methionine in protein hydrolysates with Lactobacillus fermenti 36.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985629"}
{"pmid": "20985630", "title": "Investigations of amino acids, peptides, and proteins; the determination of threonine in protein hydrolysates with Lactobacillus fermenti 36.", "content": "Investigations of amino acids, peptides, and proteins; the determination of threonine in protein hydrolysates with Lactobacillus fermenti 36.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985630"}
{"pmid": "20985631", "title": "Some relationships between the amino acid contents of proteins and their nutritive values for the rat.", "content": "Some relationships between the amino acid contents of proteins and their nutritive values for the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985631"}
{"pmid": "20985632", "title": "Changes in the inorganic constituents of developing salmon eggs.", "content": "Changes in the inorganic constituents of developing salmon eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985632"}
{"pmid": "20985633", "title": "The adaptation of the Beckman spectrophotometer to measurements on minute quantities of biological materials.", "content": "The adaptation of the Beckman spectrophotometer to measurements on minute quantities of biological materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985633"}
{"pmid": "20985634", "title": "A spectrophotometric study of the competition of methemoglobin and cytochrome oxidase for cyanide in vitro.", "content": "A spectrophotometric study of the competition of methemoglobin and cytochrome oxidase for cyanide in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985634"}
{"pmid": "20985635", "title": "Observations on vitamin Bc conjugase from hog kidney.", "content": "Observations on vitamin Bc conjugase from hog kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985635"}
{"pmid": "20985636", "title": "The response of Lactobacillus casei and Streptococcus faecalis to vitamin Bc and vitamin Bc conjugate.", "content": "The response of Lactobacillus casei and Streptococcus faecalis to vitamin Bc and vitamin Bc conjugate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985636"}
{"pmid": "20985637", "title": "Studies on the nature of carbohydrate activators of potato phosphorylase.", "content": "Studies on the nature of carbohydrate activators of potato phosphorylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985637"}
{"pmid": "20985638", "title": "Vitamin content of mouse epidermis during methylcholanthrene carcinogenesis; biotin, choline, inositol, rho-aminobenzoic acid, and pyridoxine.", "content": "Vitamin content of mouse epidermis during methylcholanthrene carcinogenesis; biotin, choline, inositol, rho-aminobenzoic acid, and pyridoxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985638"}
{"pmid": "20985639", "title": "The hydrolysis of hydantoin by various tissues.", "content": "The hydrolysis of hydantoin by various tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985639"}
{"pmid": "20985641", "title": "Pressure and protein denaturation.", "content": "Pressure and protein denaturation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985641"}
{"pmid": "20985640", "title": "Transamination in green plants.", "content": "Transamination in green plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985640"}
{"pmid": "20985642", "title": "The quinine-oxidizing enzyme and liver aldehyde oxidase.", "content": "The quinine-oxidizing enzyme and liver aldehyde oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985642"}
{"pmid": "20985643", "title": "A modified procedure for the preparation of protoporphyrin IX dimethyl ester from hemoglobin.", "content": "A modified procedure for the preparation of protoporphyrin IX dimethyl ester from hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985643"}
{"pmid": "20985644", "title": "The effect of hypophysectomy and adrenocorticotropic hormone on the alkaline phosphatase of rat plasma.", "content": "The effect of hypophysectomy and adrenocorticotropic hormone on the alkaline phosphatase of rat plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985644"}
{"pmid": "20985645", "title": "The estimation of lysozyme by a viscosimetric method.", "content": "The estimation of lysozyme by a viscosimetric method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985645"}
{"pmid": "20985646", "title": "Lysozyme of plant origin.", "content": "Lysozyme of plant origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985646"}
{"pmid": "20985647", "title": "The conjugated, non-protein, amino acids of plasma; postabsorptive concentrations of human plasma, serum, and erythrocytes.", "content": "The conjugated, non-protein, amino acids of plasma; postabsorptive concentrations of human plasma, serum, and erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985647"}
{"pmid": "20985648", "title": "The spectrophotometric estimation of hexuronates (expressed as glucuronic acid) in plasma or serum.", "content": "The spectrophotometric estimation of hexuronates (expressed as glucuronic acid) in plasma or serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985648"}
{"pmid": "20985649", "title": "The thiourea analogue of desthiobiotin.", "content": "The thiourea analogue of desthiobiotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985649"}
{"pmid": "20985650", "title": "Streptococcal fibrinolysin.", "content": "Streptococcal fibrinolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985650"}
{"pmid": "20985651", "title": "A heat-labile stimulatory factor for Streptococcus faecalis R.", "content": "A heat-labile stimulatory factor for Streptococcus faecalis R.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985651"}
{"pmid": "20985652", "title": "The differential effect of biotin sulfone and gamma-(3,4-ureylenecyclohexyl) butyric acid upon the microbiological activity of biotin and oxybiotin.", "content": "The differential effect of biotin sulfone and gamma-(3,4-ureylenecyclohexyl) butyric acid upon the microbiological activity of biotin and oxybiotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985652"}
{"pmid": "20985653", "title": "The occurrence of a pellagragenic agent in corn.", "content": "The occurrence of a pellagragenic agent in corn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985653"}
{"pmid": "20985654", "title": "Factors of influence in producing a stable result in the treatment of malocclusion.", "content": "Factors of influence in producing a stable result in the treatment of malocclusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985654"}
{"pmid": "20985655", "title": "Surgical treatment of deformities of the jaw.", "content": "Surgical treatment of deformities of the jaw.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985655"}
{"pmid": "20985657", "title": "Development of the head illustrated by sections of human fetal material.", "content": "Development of the head illustrated by sections of human fetal material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985657"}
{"pmid": "20985656", "title": "Psychotherapy in orthodontics.", "content": "Psychotherapy in orthodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985656"}
{"pmid": "20985658", "title": "A survey of oral carcinoma at the Columbia-Presbyterian Medical Center.", "content": "A survey of oral carcinoma at the Columbia-Presbyterian Medical Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985658"}
{"pmid": "20985659", "title": "The effect of zinc oxide eugenol cement on penicillin.", "content": "The effect of zinc oxide eugenol cement on penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985659"}
{"pmid": "20985660", "title": "The orofacial cripple.", "content": "The orofacial cripple.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985660"}
{"pmid": "20985661", "title": "Posterior growth of maxilla.", "content": "Posterior growth of maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985661"}
{"pmid": "20985662", "title": "The caries problem.", "content": "The caries problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985662"}
{"pmid": "20985664", "title": "Pregnancy gingivitis; history, classification, etiology.", "content": "Pregnancy gingivitis; history, classification, etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985664"}
{"pmid": "20985663", "title": "The effects of large doses of a vitamin D preparation on the oral mucous membranes of human beings.", "content": "The effects of large doses of a vitamin D preparation on the oral mucous membranes of human beings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985663"}
{"pmid": "20985668", "title": "A rapid dental treatment for the prevention aerotitis media.", "content": "A rapid dental treatment for the prevention aerotitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985668"}
{"pmid": "20985669", "title": "Rationale of denture retention.", "content": "Rationale of denture retention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985669"}
{"pmid": "20985670", "title": "The excision of hyperplastic tissues by electrosurgery.", "content": "The excision of hyperplastic tissues by electrosurgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985670"}
{"pmid": "20985671", "title": "Temporomandibular articulation in perspective.", "content": "Temporomandibular articulation in perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985671"}
{"pmid": "20985672", "title": "Symmetrically occurring supernumerary incisors; a case report.", "content": "Symmetrically occurring supernumerary incisors; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985672"}
{"pmid": "20985673", "title": "Gold-porcelain crown.", "content": "Gold-porcelain crown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985673"}
{"pmid": "20985678", "title": "Abrasives in dentifrices.", "content": "Abrasives in dentifrices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985678"}
{"pmid": "20985681", "title": "The effects of heat on vital dentine and dental pulp.", "content": "The effects of heat on vital dentine and dental pulp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985681"}
{"pmid": "20985682", "title": "Tissue response to orthodontic forces.", "content": "Tissue response to orthodontic forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985682"}
{"pmid": "20985674", "title": "Backgrounds of fluorine therapy in dentistry.", "content": "Backgrounds of fluorine therapy in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985674"}
{"pmid": "20985683", "title": "The effects of glycerite of hydrogen peroxide on the type and number of oral organisms.", "content": "The effects of glycerite of hydrogen peroxide on the type and number of oral organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985683"}
{"pmid": "20985684", "title": "Clinical and experimental aspects of vitamin A deficiency as it relates to oral and dental health.", "content": "Clinical and experimental aspects of vitamin A deficiency as it relates to oral and dental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985684"}
{"pmid": "20985675", "title": "The periodontal structures in experimental diabetes.", "content": "The periodontal structures in experimental diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985675"}
{"pmid": "20985685", "title": "Using DDT for fly control.", "content": "Using DDT for fly control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985685"}
{"pmid": "20985686", "title": "High frequency heating produces mold-free bread.", "content": "High frequency heating produces mold-free bread.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985686"}
{"pmid": "20985687", "title": "The dietitian and the present food shortage.", "content": "The dietitian and the present food shortage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985687"}
{"pmid": "20985688", "title": "Controversial aspects; yeast in human nutrition.", "content": "Controversial aspects; yeast in human nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985688"}
{"pmid": "20985689", "title": "Nutritional improvement of cereal flours and cereal grains.", "content": "Nutritional improvement of cereal flours and cereal grains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985689"}
{"pmid": "20985690", "title": "Plasma ascorbic acid and hemoglobin values.", "content": "Plasma ascorbic acid and hemoglobin values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985690"}
{"pmid": "20985691", "title": "Vitamin retention in frozen peas and frozen green beans in quantity food service.", "content": "Vitamin retention in frozen peas and frozen green beans in quantity food service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985691"}
{"pmid": "20985692", "title": "Effect of large-scale methods of preparation on vitamin content of food; carrots.", "content": "Effect of large-scale methods of preparation on vitamin content of food; carrots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985692"}
{"pmid": "20985693", "title": "Nutrition problems of the Shanghai internment camps.", "content": "Nutrition problems of the Shanghai internment camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985693"}
{"pmid": "20985695", "title": "What is the cause of diabetes mellitus in man?", "content": "What is the cause of diabetes mellitus in man?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985695"}
{"pmid": "20985694", "title": "The use of carbohydrate in diabetic acidosis.", "content": "The use of carbohydrate in diabetic acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985694"}
{"pmid": "20985696", "title": "Medical management of the diabetic patient during an acute abdominal emergency.", "content": "Medical management of the diabetic patient during an acute abdominal emergency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985696"}
{"pmid": "20985697", "title": "Recent advances in the management of gangrene and infections in patients with diabetes mellitus.", "content": "Recent advances in the management of gangrene and infections in patients with diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985697"}
{"pmid": "20985698", "title": "Carbohydrate metabolism in traumatic shock.", "content": "Carbohydrate metabolism in traumatic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985698"}
{"pmid": "20985699", "title": "Factors affecting fat transport in the animal body.", "content": "Factors affecting fat transport in the animal body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985699"}
{"pmid": "20985700", "title": "Evaluation of blood sugar tests: significance of the nonglucose reducing substances and the arteriovenous blood sugar difference.", "content": "Evaluation of blood sugar tests: significance of the nonglucose reducing substances and the arteriovenous blood sugar difference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985700"}
{"pmid": "20985701", "title": "Chronic relapsing pancreatitis; a study of twenty-nine cases without associated disease of the biliary or gastro-intestinal tract.", "content": "Chronic relapsing pancreatitis; a study of twenty-nine cases without associated disease of the biliary or gastro-intestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985701"}
{"pmid": "20985702", "title": "A review of dietary and related habits in patients with malignant gastric neoplasms.", "content": "A review of dietary and related habits in patients with malignant gastric neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985702"}
{"pmid": "20985703", "title": "Amoebic infection of the liver as seen in North Carolina.", "content": "Amoebic infection of the liver as seen in North Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985703"}
{"pmid": "20985704", "title": "Chronic erosive, granulomatous, atrophic gastritis; a case report of a rare disease.", "content": "Chronic erosive, granulomatous, atrophic gastritis; a case report of a rare disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985704"}
{"pmid": "20985705", "title": "Experimental studies on allergic cholecystitis.", "content": "Experimental studies on allergic cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985705"}
{"pmid": "20985706", "title": "The neutralization of gastric acidity with anion exchange resins.", "content": "The neutralization of gastric acidity with anion exchange resins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985706"}
{"pmid": "20985707", "title": "Predecessors of Meulengracht in the prompt feeding of patients with hematemesis.", "content": "Predecessors of Meulengracht in the prompt feeding of patients with hematemesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985707"}
{"pmid": "20985708", "title": "EXPERIMENTAL allergic pseudocholecystitis.", "content": "EXPERIMENTAL allergic pseudocholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985708"}
{"pmid": "20985709", "title": "THE mode of production of pain arising in the gallbladder region.", "content": "THE mode of production of pain arising in the gallbladder region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985709"}
{"pmid": "20985710", "title": "Benign stricture of the esophagus.", "content": "Benign stricture of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985710"}
{"pmid": "20985711", "title": "Hepatitis as observed in an Army general hospital.", "content": "Hepatitis as observed in an Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985711"}
{"pmid": "20985712", "title": "Chronic relapsing pancreatitis; a study of 29 cases without associated disease of the biliary or gastrointestinal tract.", "content": "Chronic relapsing pancreatitis; a study of 29 cases without associated disease of the biliary or gastrointestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985712"}
{"pmid": "20985713", "title": "Histamine stimulated fractional gastric analyses; the diagnostic value of total secretion.", "content": "Histamine stimulated fractional gastric analyses; the diagnostic value of total secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985713"}
{"pmid": "20985714", "title": "Heterotopic pancreatic tissue in the region of the pyloric orifice; a radiological and pathological analysis of five cases of clinically suspected peptic ulcer in which only pancreatic rests were found.", "content": "Heterotopic pancreatic tissue in the region of the pyloric orifice; a radiological and pathological analysis of five cases of clinically suspected peptic ulcer in which only pancreatic rests were found.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985714"}
{"pmid": "20985715", "title": "The effect of two new histamine antagonists (benadryl and compound 63) on histamine stimulated gastric secretion in the dog.", "content": "The effect of two new histamine antagonists (benadryl and compound 63) on histamine stimulated gastric secretion in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985715"}
{"pmid": "20985717", "title": "Secondary pellagra caused by multiple argentaffin carcinoma of the ileum and jejunum.", "content": "Secondary pellagra caused by multiple argentaffin carcinoma of the ileum and jejunum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985717"}
{"pmid": "20985716", "title": "The influence of benadryl (dimethylaminoethylbenz-hydryl ether hydrochloride) on gastric acidity.", "content": "The influence of benadryl (dimethylaminoethylbenz-hydryl ether hydrochloride) on gastric acidity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985716"}
{"pmid": "20985718", "title": "An ulcer which appeared in the stomach of a man receiving histamine intravenously.", "content": "An ulcer which appeared in the stomach of a man receiving histamine intravenously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985718"}
{"pmid": "20985719", "title": "Cytological studies in the Musae; meiosis in some triploid clones.", "content": "Cytological studies in the Musae; meiosis in some triploid clones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985719"}
{"pmid": "20985720", "title": "On the dot chromosomes of Drosophila repleta and D. hydei.", "content": "On the dot chromosomes of Drosophila repleta and D. hydei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985720"}
{"pmid": "20985721", "title": "Genetics of natural populations; recombination and variability in populations of Drosophila pseudoobscura.", "content": "Genetics of natural populations; recombination and variability in populations of Drosophila pseudoobscura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985721"}
{"pmid": "20985722", "title": "Inheritance in lady beetles; the form of the chitinous male genitalia in crosses of the species Hippodamia quinquestignata and H. convergens.", "content": "Inheritance in lady beetles; the form of the chitinous male genitalia in crosses of the species Hippodamia quinquestignata and H. convergens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985722"}
{"pmid": "20985723", "title": "Incipient intraspecific isolating mechanisms in Rana pipiens.", "content": "Incipient intraspecific isolating mechanisms in Rana pipiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985723"}
{"pmid": "20985724", "title": "A quantitative histological study of the pigment found in the coat-color mutants of the house mouse; variable attributes of the pigment granules.", "content": "A quantitative histological study of the pigment found in the coat-color mutants of the house mouse; variable attributes of the pigment granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985724"}
{"pmid": "20985725", "title": "Begonia species hybrids.", "content": "Begonia species hybrids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985725"}
{"pmid": "20985726", "title": "Can the sex of mammalian offspring be controlled?", "content": "Can the sex of mammalian offspring be controlled?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985726"}
{"pmid": "20985727", "title": "GENIC and cultural erosion in America.", "content": "GENIC and cultural erosion in America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985727"}
{"pmid": "20985728", "title": "The origin of Triticum spelta and its free-threshing hexaploid relatives.", "content": "The origin of Triticum spelta and its free-threshing hexaploid relatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985728"}
{"pmid": "20985730", "title": "The structure of the bands of salivary gland chromosomes.", "content": "The structure of the bands of salivary gland chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985730"}
{"pmid": "20985729", "title": "Variation of expression of polydactyly.", "content": "Variation of expression of polydactyly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985729"}
{"pmid": "20985731", "title": "Comparative rates of pollen tube establishment in diploid and tetraploid maize.", "content": "Comparative rates of pollen tube establishment in diploid and tetraploid maize.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985731"}
{"pmid": "20985732", "title": "Inheritance of three leaf types in the pineapple.", "content": "Inheritance of three leaf types in the pineapple.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985732"}
{"pmid": "20985754", "title": "Humane warfare and inhuman war; Japan and its treatment of war prisoners.", "content": "Humane warfare and inhuman war; Japan and its treatment of war prisoners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985754"}
{"pmid": "20985755", "title": "Arabism, Egypt, and Max Meyerhof.", "content": "Arabism, Egypt, and Max Meyerhof.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985755"}
{"pmid": "20985756", "title": "Mysterious deaths in history; Eusebio Valli's case.", "content": "Mysterious deaths in history; Eusebio Valli's case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985756"}
{"pmid": "20985757", "title": "Carcinoids, malignant carcinoids, and carcinoma of the vermiform appendix.", "content": "Carcinoids, malignant carcinoids, and carcinoma of the vermiform appendix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985757"}
{"pmid": "20985758", "title": "Brain waves of infants and children taken by a new method developed at Hahnemann Medical College and Hospital.", "content": "Brain waves of infants and children taken by a new method developed at Hahnemann Medical College and Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985758"}
{"pmid": "20985759", "title": "Salsolin, a new drug in the treatment of hypertension.", "content": "Salsolin, a new drug in the treatment of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985759"}
{"pmid": "20985761", "title": "Regional ileitis.", "content": "Regional ileitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985761"}
{"pmid": "20985760", "title": "Clinical otolaryngologic observations in children.", "content": "Clinical otolaryngologic observations in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985760"}
{"pmid": "20985762", "title": "Some clinical aspects of Aesculus hippocastanum.", "content": "Some clinical aspects of Aesculus hippocastanum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985762"}
{"pmid": "20985763", "title": "A brief study course in homoeopathy.", "content": "A brief study course in homoeopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985763"}
{"pmid": "20985771", "title": "Homoeopathic remedies used in treatment of ear, eye, nose and throat disease.", "content": "Homoeopathic remedies used in treatment of ear, eye, nose and throat disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985771"}
{"pmid": "20985772", "title": "The profession progresses with you.", "content": "The profession progresses with you.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985772"}
{"pmid": "20985773", "title": "Osteopathic lesions size and position of child, and motor inefficiency during labor.", "content": "Osteopathic lesions size and position of child, and motor inefficiency during labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985773"}
{"pmid": "20985774", "title": "Endometriosis.", "content": "Endometriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985774"}
{"pmid": "20985775", "title": "Foot gear of the past.", "content": "Foot gear of the past.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985775"}
{"pmid": "20985776", "title": "MEXICO'S cardiac institute.", "content": "MEXICO'S cardiac institute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985776"}
{"pmid": "20985777", "title": "Contemporary planning down under.", "content": "Contemporary planning down under.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985777"}
{"pmid": "20985778", "title": "Early to rise after major surgery.", "content": "Early to rise after major surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985778"}
{"pmid": "20985779", "title": "The hospital library turns professional.", "content": "The hospital library turns professional.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985779"}
{"pmid": "20985780", "title": "Transfusion clinic for out-patients.", "content": "Transfusion clinic for out-patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985780"}
{"pmid": "20985781", "title": "Methods of measuring the quality of nursing care.", "content": "Methods of measuring the quality of nursing care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985781"}
{"pmid": "20985782", "title": "Physical and occupational therapy.", "content": "Physical and occupational therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985782"}
{"pmid": "20985783", "title": "An 11 point program for the making of a modern hospital administrator.", "content": "An 11 point program for the making of a modern hospital administrator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985783"}
{"pmid": "20985784", "title": "Standards for psychiatric hospitals and out-patient clinics.", "content": "Standards for psychiatric hospitals and out-patient clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985784"}
{"pmid": "20985786", "title": "The relationship between the virus of infectious ectromelia of mice and vaccinia virus.", "content": "The relationship between the virus of infectious ectromelia of mice and vaccinia virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985786"}
{"pmid": "20985785", "title": "Isopropyl alcohol as a disinfectant.", "content": "Isopropyl alcohol as a disinfectant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985785"}
{"pmid": "20985787", "title": "Serologic studies in typhus-vaccinated individuals; Weil-Felix and complement-fixation findings in epidemic typhus fever occurring in the vaccinated.", "content": "Serologic studies in typhus-vaccinated individuals; Weil-Felix and complement-fixation findings in epidemic typhus fever occurring in the vaccinated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985787"}
{"pmid": "20985788", "title": "Spectrophotometric standardization of complement for fixation tests.", "content": "Spectrophotometric standardization of complement for fixation tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985788"}
{"pmid": "20985789", "title": "Studies in complement fixation; spectrophotometric titration of complement; construction of graphs for direct determination of the 50 per cent hemolytic unit.", "content": "Studies in complement fixation; spectrophotometric titration of complement; construction of graphs for direct determination of the 50 per cent hemolytic unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985789"}
{"pmid": "20985790", "title": "The effect of nutritional deficiencies on the development of neutralizing antibodies and associated changes in cerebral resistance against the virus of western equine encephalomyelitis.", "content": "The effect of nutritional deficiencies on the development of neutralizing antibodies and associated changes in cerebral resistance against the virus of western equine encephalomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985790"}
{"pmid": "20985791", "title": "Experiments on vaccination of human beings against epidemic influenza.", "content": "Experiments on vaccination of human beings against epidemic influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985791"}
{"pmid": "20985792", "title": "Further studies on the influence of x-rays on the phagocytic indices of healthy rabbits.", "content": "Further studies on the influence of x-rays on the phagocytic indices of healthy rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985792"}
{"pmid": "20985793", "title": "Studies in human malaria; attempts to influence relapsing vivax malaria by treatment of patients with vaccine (Pl. vivax).", "content": "Studies in human malaria; attempts to influence relapsing vivax malaria by treatment of patients with vaccine (Pl. vivax).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985793"}
{"pmid": "20985794", "title": "Studies in human malaria; an attempt at vaccination of paretics against blood-borne infection with Pl. vivax.", "content": "Studies in human malaria; an attempt at vaccination of paretics against blood-borne infection with Pl. vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985794"}
{"pmid": "20985795", "title": "Studies in human malaria; an attempt at vaccination of volunteers against mosquito-borne infection with Pl. vivax.", "content": "Studies in human malaria; an attempt at vaccination of volunteers against mosquito-borne infection with Pl. vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985795"}
{"pmid": "20985796", "title": "Punishment in prisons.", "content": "Punishment in prisons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985796"}
{"pmid": "20985797", "title": "Cooperative plan for the development of a small plant health and industrial hygiene program in New York City.", "content": "Cooperative plan for the development of a small plant health and industrial hygiene program in New York City.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985797"}
{"pmid": "20985798", "title": "Chest conditions simulating silicosis.", "content": "Chest conditions simulating silicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985798"}
{"pmid": "20985799", "title": "Coordination of official industrial hygiene program with other agencies.", "content": "Coordination of official industrial hygiene program with other agencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985799"}
{"pmid": "20985800", "title": "An occupational dermatitis due to the inhalation of trichlorethylene gas; preliminary report.", "content": "An occupational dermatitis due to the inhalation of trichlorethylene gas; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985800"}
{"pmid": "20985801", "title": "Administrative aspects of mass radiography.", "content": "Administrative aspects of mass radiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985801"}
{"pmid": "20985802", "title": "Further blood and neurologic studies of a group of employees in a manganese crushing mill.", "content": "Further blood and neurologic studies of a group of employees in a manganese crushing mill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985802"}
{"pmid": "20985803", "title": "Treatment of myopathies and industrial injuries with wheat germ oil.", "content": "Treatment of myopathies and industrial injuries with wheat germ oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985803"}
{"pmid": "20985804", "title": "Clinical criteria for rehabilitation of patients with pulmonary tuberculosis.", "content": "Clinical criteria for rehabilitation of patients with pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985804"}
{"pmid": "20985806", "title": "Retaining and reemployment administration.", "content": "Retaining and reemployment administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985806"}
{"pmid": "20985805", "title": "A field agent discovers industry.", "content": "A field agent discovers industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985805"}
{"pmid": "20985808", "title": "Development of the Rehabilitation Center in Connecticut.", "content": "Development of the Rehabilitation Center in Connecticut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985808"}
{"pmid": "20985807", "title": "Work adjustment in rehabilitation.", "content": "Work adjustment in rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985807"}
{"pmid": "20985809", "title": "Educational and vocational aspects of the problem of the cerebral palsied.", "content": "Educational and vocational aspects of the problem of the cerebral palsied.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985809"}
{"pmid": "20985810", "title": "The medical administrative consultant in the State program of vocational rehabilitation.", "content": "The medical administrative consultant in the State program of vocational rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985810"}
{"pmid": "20985811", "title": "RUDIMENTS of rehabilitation.", "content": "RUDIMENTS of rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985811"}
{"pmid": "20985812", "title": "A program of service for the visually handicapped.", "content": "A program of service for the visually handicapped.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985812"}
{"pmid": "20985813", "title": "Psychiatric problems in children in Oak Ridge.", "content": "Psychiatric problems in children in Oak Ridge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985813"}
{"pmid": "20985814", "title": "OLD age assistance in Minnesota; budgeted requirements.", "content": "OLD age assistance in Minnesota; budgeted requirements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985814"}
{"pmid": "20985817", "title": "Pathology of Belgian Congo during the war.", "content": "Pathology of Belgian Congo during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985817"}
{"pmid": "20985818", "title": "The virulence of lepra bacilli.", "content": "The virulence of lepra bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985818"}
{"pmid": "20985819", "title": "Studies of the lepromin test.", "content": "Studies of the lepromin test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985819"}
{"pmid": "20985820", "title": "The diagnostic value of sternal puncture in blood diseases; with a report of five cases.", "content": "The diagnostic value of sternal puncture in blood diseases; with a report of five cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985820"}
{"pmid": "20985821", "title": "An anesthetic with prolonged action.", "content": "An anesthetic with prolonged action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985821"}
{"pmid": "20985822", "title": "Depot-action of drugs; experiments, giving special consideration to local anesthetics.", "content": "Depot-action of drugs; experiments, giving special consideration to local anesthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985822"}
{"pmid": "20985823", "title": "The methylene blue test for bilirubin; a short note on its value in liver diseases.", "content": "The methylene blue test for bilirubin; a short note on its value in liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985823"}
{"pmid": "20985824", "title": "Short wave therapy; with an outline of the development of electrotherapy.", "content": "Short wave therapy; with an outline of the development of electrotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985824"}
{"pmid": "20985826", "title": "Retinitis pigmentosa.", "content": "Retinitis pigmentosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985826"}
{"pmid": "20985825", "title": "The treatment of retinitis pigmentosa with intramuscular injections of cod liver oil.", "content": "The treatment of retinitis pigmentosa with intramuscular injections of cod liver oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985825"}
{"pmid": "20985827", "title": "The implantation of preserved placenta in retinitis pigmentosa.", "content": "The implantation of preserved placenta in retinitis pigmentosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985827"}
{"pmid": "20985828", "title": "The implantation of preserved liver in retinitis pigmentosa.", "content": "The implantation of preserved liver in retinitis pigmentosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985828"}
{"pmid": "20985829", "title": "Natural and acquired immunity to influenza; the reactivation of the influenza virus from an immune serum-virus mixture.", "content": "Natural and acquired immunity to influenza; the reactivation of the influenza virus from an immune serum-virus mixture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985829"}
{"pmid": "20985830", "title": "Vital studies of the neuroplasm.", "content": "Vital studies of the neuroplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985830"}
{"pmid": "20985831", "title": "Experimental studies of lysozyme.", "content": "Experimental studies of lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985831"}
{"pmid": "20985832", "title": "Lysozyme in surgery.", "content": "Lysozyme in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985832"}
{"pmid": "20985833", "title": "Anti-reticular cytotoxic serum in chronic skin ulcers.", "content": "Anti-reticular cytotoxic serum in chronic skin ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985833"}
{"pmid": "20985834", "title": "Lysozyme in the treatment of diarrhea in children.", "content": "Lysozyme in the treatment of diarrhea in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985834"}
{"pmid": "20985835", "title": "Medical research mission to the Soviet Union.", "content": "Medical research mission to the Soviet Union.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985835"}
{"pmid": "20985843", "title": "Effects of plasma and fluid on pulmonary complications in burned patients; study of the effects in the victims of the Cocoanut Grove fire.", "content": "Effects of plasma and fluid on pulmonary complications in burned patients; study of the effects in the victims of the Cocoanut Grove fire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985843"}
{"pmid": "20985844", "title": "Hyperactive cardioinhibitory carotid sinus reflex.", "content": "Hyperactive cardioinhibitory carotid sinus reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985844"}
{"pmid": "20985846", "title": "Systemic infection due to Torula histolytica (Cryptococcus hominis); effect of chemotherapeutic agents in experimentally produced infections.", "content": "Systemic infection due to Torula histolytica (Cryptococcus hominis); effect of chemotherapeutic agents in experimentally produced infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985846"}
{"pmid": "20985845", "title": "Systemic infection due to Torula histolytica (Cryptococcus hominis); report of four cases and review of the literature.", "content": "Systemic infection due to Torula histolytica (Cryptococcus hominis); report of four cases and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985845"}
{"pmid": "20985847", "title": "Role of histamine and acetylcholine in the mechanism of heat allergy; report of studies on a soldier.", "content": "Role of histamine and acetylcholine in the mechanism of heat allergy; report of studies on a soldier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985847"}
{"pmid": "20985848", "title": "Chronic hemolytic anemia; observations on the effect of fat content of the diet and multiple red cell transfusions.", "content": "Chronic hemolytic anemia; observations on the effect of fat content of the diet and multiple red cell transfusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985848"}
{"pmid": "20985849", "title": "Concentrated human albumin in the treatment of shock.", "content": "Concentrated human albumin in the treatment of shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985849"}
{"pmid": "20985850", "title": "Review of neuropsychiatry for 1945.", "content": "Review of neuropsychiatry for 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985850"}
{"pmid": "20985878", "title": "The haemagglutinins of vaccinia and ectromelia viruses.", "content": "The haemagglutinins of vaccinia and ectromelia viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985878"}
{"pmid": "20985879", "title": "The production of vaccinia haemagglutinin in rabbit skin.", "content": "The production of vaccinia haemagglutinin in rabbit skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985879"}
{"pmid": "20985880", "title": "Mumps; isolation and cultivation of the virus in the chick embryo.", "content": "Mumps; isolation and cultivation of the virus in the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985880"}
{"pmid": "20985881", "title": "Thermal inactivation of tomato spotted wilt virus.", "content": "Thermal inactivation of tomato spotted wilt virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985881"}
{"pmid": "20985882", "title": "Inactivation of tomato spotted wilt virus by salicylate.", "content": "Inactivation of tomato spotted wilt virus by salicylate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985882"}
{"pmid": "20985883", "title": "The plate test for coagulase production by staphylococci.", "content": "The plate test for coagulase production by staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985883"}
{"pmid": "20985884", "title": "Utilization of molecular hydrogen by bacteria.", "content": "Utilization of molecular hydrogen by bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985884"}
{"pmid": "20985885", "title": "Antibacterial substances produced by flowering plants; preliminary survey.", "content": "Antibacterial substances produced by flowering plants; preliminary survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985885"}
{"pmid": "20985886", "title": "The estimation of adrenaline.", "content": "The estimation of adrenaline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985886"}
{"pmid": "20985887", "title": "Antibiotics from Victorian Basidiomycetes.", "content": "Antibiotics from Victorian Basidiomycetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985887"}
{"pmid": "20985888", "title": "The detoxication of Cl. welchii type D toxin by formaldehyde.", "content": "The detoxication of Cl. welchii type D toxin by formaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985888"}
{"pmid": "20985889", "title": "Criteria of pathogenicity in staphylococci.", "content": "Criteria of pathogenicity in staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985889"}
{"pmid": "20985893", "title": "Penetrating craniocerebral wounds in war (historical).", "content": "Penetrating craniocerebral wounds in war (historical).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985893"}
{"pmid": "20985892", "title": "The lymphomatous diseases.", "content": "The lymphomatous diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985892"}
{"pmid": "20985894", "title": "Further comments on early ambulation.", "content": "Further comments on early ambulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985894"}
{"pmid": "20985895", "title": "Conditions of the male and female urethra as demonstrated by cystourethrography.", "content": "Conditions of the male and female urethra as demonstrated by cystourethrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985895"}
{"pmid": "20985896", "title": "Placenta previa and premature separation of the placenta.", "content": "Placenta previa and premature separation of the placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985896"}
{"pmid": "20985902", "title": "The value of physical diagnosis in diseases of respiration.", "content": "The value of physical diagnosis in diseases of respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985902"}
{"pmid": "20985901", "title": "The hyperventilation syndrome; a psychosomatic problem.", "content": "The hyperventilation syndrome; a psychosomatic problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985901"}
{"pmid": "20985903", "title": "LONGEVITY and old age; doctors report interesting cases of long-lived persons in Punjab.", "content": "LONGEVITY and old age; doctors report interesting cases of long-lived persons in Punjab.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985903"}
{"pmid": "20985904", "title": "Address to graduating class, Western Reserve Medical School, March 18, 1946.", "content": "Address to graduating class, Western Reserve Medical School, March 18, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985904"}
{"pmid": "20985905", "title": "Twelve years experience with artificial fever therapy at Cleveland City Hospital.", "content": "Twelve years experience with artificial fever therapy at Cleveland City Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985905"}
{"pmid": "20985906", "title": "Mediastinal emphysema.", "content": "Mediastinal emphysema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985906"}
{"pmid": "20985907", "title": "SOME poet-physicians.", "content": "SOME poet-physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985907"}
{"pmid": "20985908", "title": "PENICILLIN in the treatment of syphilis.", "content": "PENICILLIN in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985908"}
{"pmid": "20985909", "title": "Neurofibroma and neurilemoma.", "content": "Neurofibroma and neurilemoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985909"}
{"pmid": "20985910", "title": "Phlyctenular conjunctivitis in four children of one family.", "content": "Phlyctenular conjunctivitis in four children of one family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985910"}
{"pmid": "20985911", "title": "The effect on rats of a diet with a high content of protein derived from food yeast.", "content": "The effect on rats of a diet with a high content of protein derived from food yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985911"}
{"pmid": "20985912", "title": "A note on the effect of training on the physique of adolescent boys.", "content": "A note on the effect of training on the physique of adolescent boys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985912"}
{"pmid": "20985913", "title": "Recent advances in nutrition.", "content": "Recent advances in nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985913"}
{"pmid": "20985914", "title": "BERIBERI heart failure.", "content": "BERIBERI heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985914"}
{"pmid": "20985915", "title": "[Paget's disease].", "content": "[Paget's disease].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985915"}
{"pmid": "20985924", "title": "Symposium; the hospital as a public service unit; the directors.", "content": "Symposium; the hospital as a public service unit; the directors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985924"}
{"pmid": "20985923", "title": "Symposium; the hospital as a public service unit; the staff.", "content": "Symposium; the hospital as a public service unit; the staff.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985923"}
{"pmid": "20985925", "title": "Symposium; the hospital as a public service unit; the administrator.", "content": "Symposium; the hospital as a public service unit; the administrator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985925"}
{"pmid": "20985926", "title": "Penicillin in rat-bite fever; a case report.", "content": "Penicillin in rat-bite fever; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985926"}
{"pmid": "20985927", "title": "Malaria.", "content": "Malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985927"}
{"pmid": "20985928", "title": "Struma lymphomatosa.", "content": "Struma lymphomatosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985928"}
{"pmid": "20985930", "title": "Physicians as metaphysicians.", "content": "Physicians as metaphysicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985930"}
{"pmid": "20985929", "title": "Recent advances in cutaneous medicine.", "content": "Recent advances in cutaneous medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985929"}
{"pmid": "20985931", "title": "Hazards of compulsory health insurance.", "content": "Hazards of compulsory health insurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985931"}
{"pmid": "20985932", "title": "Building health through school education.", "content": "Building health through school education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985932"}
{"pmid": "20985934", "title": "Peritonitis of appendiceal origin.", "content": "Peritonitis of appendiceal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985934"}
{"pmid": "20985933", "title": "Hemochromatosis; report of case with necropsy.", "content": "Hemochromatosis; report of case with necropsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985933"}
{"pmid": "20985936", "title": "Rocky Mountain spotted fever; a case treated with p-aminobenzoic acid.", "content": "Rocky Mountain spotted fever; a case treated with p-aminobenzoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985936"}
{"pmid": "20985949", "title": "Medical jurisprudence; medical jurists at work.", "content": "Medical jurisprudence; medical jurists at work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985949"}
{"pmid": "20985948", "title": "The story of the Red Cross.", "content": "The story of the Red Cross.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985948"}
{"pmid": "20985935", "title": "Treatment of an obstinate case of Aerobacter bacilluria with streptomycin.", "content": "Treatment of an obstinate case of Aerobacter bacilluria with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985935"}
{"pmid": "20985951", "title": "Medical jurisprudence; the Ruxton case.", "content": "Medical jurisprudence; the Ruxton case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985951"}
{"pmid": "20985950", "title": "Medical jurisprudence; premeditated murder.", "content": "Medical jurisprudence; premeditated murder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985950"}
{"pmid": "20985974", "title": "Malaria in soldiers returned from abroad.", "content": "Malaria in soldiers returned from abroad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985974"}
{"pmid": "20985975", "title": "Non-purulent pleural effusions.", "content": "Non-purulent pleural effusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985975"}
{"pmid": "20985976", "title": "A tour of the United States plastic surgery centres.", "content": "A tour of the United States plastic surgery centres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985976"}
{"pmid": "20985978", "title": "[Acute thyroiditis in three persons of the same family].", "content": "[Acute thyroiditis in three persons of the same family].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985978"}
{"pmid": "20985979", "title": "[Cold agglutinins in primary atypical pneumonia].", "content": "[Cold agglutinins in primary atypical pneumonia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985979"}
{"pmid": "20985977", "title": "[The treatment of thyrotoxicosis with thiouracil].", "content": "[The treatment of thyrotoxicosis with thiouracil].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985977"}
{"pmid": "20985980", "title": "[Newcastle disease (subconjunctival haemorrhage) in man].", "content": "[Newcastle disease (subconjunctival haemorrhage) in man].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985980"}
{"pmid": "20985981", "title": "[The development of cardiological problems in the last 50 years].", "content": "[The development of cardiological problems in the last 50 years].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985981"}
{"pmid": "20985982", "title": "[Blackwater fever after delivery].", "content": "[Blackwater fever after delivery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985982"}
{"pmid": "20985983", "title": "[The lytic action of normal faeces on the vegetative form of Entamoeba histolytica].", "content": "[The lytic action of normal faeces on the vegetative form of Entamoeba histolytica].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985983"}
{"pmid": "20985984", "title": "[Degeneratio colloidalis solaris].", "content": "[Degeneratio colloidalis solaris].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985984"}
{"pmid": "20985985", "title": "[Retroflexion of the uterus and sterility].", "content": "[Retroflexion of the uterus and sterility].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985985"}
{"pmid": "20985986", "title": "[A case of chronic myelogenous leukemia complicated by pregnancy].", "content": "[A case of chronic myelogenous leukemia complicated by pregnancy].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985986"}
{"pmid": "20985987", "title": "[The results of health examinations of 2000 young Palestinian adults].", "content": "[The results of health examinations of 2000 young Palestinian adults].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985987"}
{"pmid": "20985988", "title": "Indian neurological interlude.", "content": "Indian neurological interlude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985988"}
{"pmid": "20985989", "title": "The reticulo-endothelial system and resistance to disease.", "content": "The reticulo-endothelial system and resistance to disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985989"}
{"pmid": "20985990", "title": "Observations on a budding fungus-like form of E. coli in the urine of a patient receiving penicillin.", "content": "Observations on a budding fungus-like form of E. coli in the urine of a patient receiving penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985990"}
{"pmid": "20985991", "title": "Penicillin; its effect on bacterial morphology.", "content": "Penicillin; its effect on bacterial morphology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985991"}
{"pmid": "20985993", "title": "Value in medical records.", "content": "Value in medical records.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985993"}
{"pmid": "20985994", "title": "Appendicitis during labor; report of case.", "content": "Appendicitis during labor; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985994"}
{"pmid": "20985992", "title": "Acute pericarditis simulating coronary thrombosis.", "content": "Acute pericarditis simulating coronary thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20985992"}
{"pmid": "20986019", "title": "An outbreak of polioencephalitis among Navy Cadets, possibly food borne.", "content": "An outbreak of polioencephalitis among Navy Cadets, possibly food borne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986019"}
{"pmid": "20986020", "title": "March fracture of the fibula in athletes.", "content": "March fracture of the fibula in athletes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986020"}
{"pmid": "20986021", "title": "Prostatic cancer treated by orchiectomy; the five year results.", "content": "Prostatic cancer treated by orchiectomy; the five year results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986021"}
{"pmid": "20986022", "title": "Ruptured intervertebral disk simulating angina pectoris.", "content": "Ruptured intervertebral disk simulating angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986022"}
{"pmid": "20986023", "title": "Facts and fallacies in the integration of national voluntary health agencies.", "content": "Facts and fallacies in the integration of national voluntary health agencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986023"}
{"pmid": "20986024", "title": "Thioglycolic acid poisoning in connection with the cold wave process.", "content": "Thioglycolic acid poisoning in connection with the cold wave process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986024"}
{"pmid": "20986025", "title": "Gamma globulin not effective in prophylaxis of epidemic respiratory infections.", "content": "Gamma globulin not effective in prophylaxis of epidemic respiratory infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986025"}
{"pmid": "20986026", "title": "Skin blisters caused by vesicant beetles.", "content": "Skin blisters caused by vesicant beetles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986026"}
{"pmid": "20986027", "title": "Cancer prevention clinics.", "content": "Cancer prevention clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986027"}
{"pmid": "20986028", "title": "Basic facts regarding x-ray and radium therapy.", "content": "Basic facts regarding x-ray and radium therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986028"}
{"pmid": "20986029", "title": "The urinary tract in pelvic cancer.", "content": "The urinary tract in pelvic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986029"}
{"pmid": "20986030", "title": "The Chicago cancer prevention clinics.", "content": "The Chicago cancer prevention clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986030"}
{"pmid": "20986031", "title": "Report on Field Army of the American Cancer Society.", "content": "Report on Field Army of the American Cancer Society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986031"}
{"pmid": "20986032", "title": "The American Women's Hospital in Norway.", "content": "The American Women's Hospital in Norway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986032"}
{"pmid": "20986033", "title": "Women pioneers in medicine.", "content": "Women pioneers in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986033"}
{"pmid": "20986034", "title": "Studies of thiamine metabolism in man; thiamine balance; the normal requirement of vitamin B1 and the role of fecal thiamine in human nutrition.", "content": "Studies of thiamine metabolism in man; thiamine balance; the normal requirement of vitamin B1 and the role of fecal thiamine in human nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986034"}
{"pmid": "20986035", "title": "Studies of thiamine metabolism in man; thiamine and pyrimidine excretion with special reference to the relationship between injected and excreted thiamine in normal and abnormal subjects.", "content": "Studies of thiamine metabolism in man; thiamine and pyrimidine excretion with special reference to the relationship between injected and excreted thiamine in normal and abnormal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986035"}
{"pmid": "20986037", "title": "Changes in muscle composition in alkalosis.", "content": "Changes in muscle composition in alkalosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986037"}
{"pmid": "20986036", "title": "Chemical, clinical, and immunological studies on the products of human plasma fractionation; the use of salt-poor concentrated human serum albumin solution in the treatment of hepatid cirrhosis.", "content": "Chemical, clinical, and immunological studies on the products of human plasma fractionation; the use of salt-poor concentrated human serum albumin solution in the treatment of hepatid cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986036"}
{"pmid": "20986038", "title": "Studies of streptococcal fibrinolysis; the dissimilarity of serum protease and trypsin as indicated by the separate specificities of their kinases, fibrinolysin and enterokinase.", "content": "Studies of streptococcal fibrinolysis; the dissimilarity of serum protease and trypsin as indicated by the separate specificities of their kinases, fibrinolysin and enterokinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986038"}
{"pmid": "20986039", "title": "Studies of streptococcal fibrinolysis; the inhibition of streptococcal fibrinolysis by antifibrinolysin and antiprotease.", "content": "Studies of streptococcal fibrinolysis; the inhibition of streptococcal fibrinolysis by antifibrinolysin and antiprotease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986039"}
{"pmid": "20986041", "title": "STUDIES of streptococcal fibrinolysis; clinical application of a quantitative antifibrinolysin test.", "content": "STUDIES of streptococcal fibrinolysis; clinical application of a quantitative antifibrinolysin test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986041"}
{"pmid": "20986040", "title": "Studies of streptococcal fibrinolysis; a quantitative method for the estimation of serum antifibrinolysin.", "content": "Studies of streptococcal fibrinolysis; a quantitative method for the estimation of serum antifibrinolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986040"}
{"pmid": "20986042", "title": "Effects of thyroid on creatine metabolism with a discussion of the mechanism of storage and excretion of creatine bodies.", "content": "Effects of thyroid on creatine metabolism with a discussion of the mechanism of storage and excretion of creatine bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986042"}
{"pmid": "20986043", "title": "A survey of the twenty-four-hour uric acid and urea clearances in eclampsia and severe preeclampsia.", "content": "A survey of the twenty-four-hour uric acid and urea clearances in eclampsia and severe preeclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986043"}
{"pmid": "20986044", "title": "On the increased uric acid clearance following the intravenous infusion of hypertonic glucose solutions.", "content": "On the increased uric acid clearance following the intravenous infusion of hypertonic glucose solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986044"}
{"pmid": "20986045", "title": "Edema and decreased renal blood flow in patients with chronic congestive heart failure; evidence of forward failure as the primary cause of edema.", "content": "Edema and decreased renal blood flow in patients with chronic congestive heart failure; evidence of forward failure as the primary cause of edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986045"}
{"pmid": "20986046", "title": "The effect of significant weight change on the predicted plasma volume.", "content": "The effect of significant weight change on the predicted plasma volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986046"}
{"pmid": "20986047", "title": "Serum iodine in hyperthyroidism, with particular reference to the effects of subtotal thyroidectomy.", "content": "Serum iodine in hyperthyroidism, with particular reference to the effects of subtotal thyroidectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986047"}
{"pmid": "20986048", "title": "Ballistocardiographic study of changes in cardiac output due to respiration.", "content": "Ballistocardiographic study of changes in cardiac output due to respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986048"}
{"pmid": "20986049", "title": "Properties of an anticoagulant found in the blood of a hemophiliac.", "content": "Properties of an anticoagulant found in the blood of a hemophiliac.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986049"}
{"pmid": "20986050", "title": "Studies in ascorbic acid with especial reference to the white layer; the relation of intake to blood levels in normal children and the effect of acute and chronic illness.", "content": "Studies in ascorbic acid with especial reference to the white layer; the relation of intake to blood levels in normal children and the effect of acute and chronic illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986050"}
{"pmid": "20986051", "title": "The effect of clothing on the ability of men to work in intense heat.", "content": "The effect of clothing on the ability of men to work in intense heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986051"}
{"pmid": "20986053", "title": "Thrombophlebitis migrans.", "content": "Thrombophlebitis migrans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986053"}
{"pmid": "20986052", "title": "An objective method for determining circulation time from pulmonary to systemic capillaries by the use of the oximeter.", "content": "An objective method for determining circulation time from pulmonary to systemic capillaries by the use of the oximeter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986052"}
{"pmid": "20986054", "title": "Conservation of residual hearing.", "content": "Conservation of residual hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986054"}
{"pmid": "20986055", "title": "Diphtheria and the heart.", "content": "Diphtheria and the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986055"}
{"pmid": "20986056", "title": "Severe scurvy; a clinical and hematologic study.", "content": "Severe scurvy; a clinical and hematologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986056"}
{"pmid": "20986057", "title": "The effect of folic acid (Lactobacillus casei factor) in nutritional hematopenia of monkeys.", "content": "The effect of folic acid (Lactobacillus casei factor) in nutritional hematopenia of monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986057"}
{"pmid": "20986058", "title": "Further observations on the anti-anemic properties of 5-methyl uracil.", "content": "Further observations on the anti-anemic properties of 5-methyl uracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986058"}
{"pmid": "20986059", "title": "Effect of penicillin and sulfonamides on acetylcholine synthesis and on the response of muscle to acetylcholine and potassium.", "content": "Effect of penicillin and sulfonamides on acetylcholine synthesis and on the response of muscle to acetylcholine and potassium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986059"}
{"pmid": "20986060", "title": "The antishock action of ethanol in burned mice; effect on edema formation and capillary atony.", "content": "The antishock action of ethanol in burned mice; effect on edema formation and capillary atony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986060"}
{"pmid": "20986061", "title": "The antishock action of certain drugs in burned mice.", "content": "The antishock action of certain drugs in burned mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986061"}
{"pmid": "20986063", "title": "Colorimetric diagnostic test for malaria.", "content": "Colorimetric diagnostic test for malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986063"}
{"pmid": "20986062", "title": "Therapeutic induction of fever and leucocytosis using a purified typhoid pyrogen.", "content": "Therapeutic induction of fever and leucocytosis using a purified typhoid pyrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986062"}
{"pmid": "20986064", "title": "Heberden's nodes; the association of hypertension and obesity to degenerative joint disease of the fingers.", "content": "Heberden's nodes; the association of hypertension and obesity to degenerative joint disease of the fingers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986064"}
{"pmid": "20986065", "title": "The determination of sulfonamides in tungstic acid (Folin-Wu) blood filtrates.", "content": "The determination of sulfonamides in tungstic acid (Folin-Wu) blood filtrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986065"}
{"pmid": "20986067", "title": "An improved method for the determination of plasma prothrombin.", "content": "An improved method for the determination of plasma prothrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986067"}
{"pmid": "20986066", "title": "A simply constructed metabolism cage for small rats.", "content": "A simply constructed metabolism cage for small rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986066"}
{"pmid": "20986068", "title": "Antisheep amboceptor production with elimination of rabbit shock.", "content": "Antisheep amboceptor production with elimination of rabbit shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986068"}
{"pmid": "20986069", "title": "A rapid method for drying oxalate solutions.", "content": "A rapid method for drying oxalate solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986069"}
{"pmid": "20986070", "title": "Perforation of choledochus cyst with biliary peritonitis; report of a case submitted to a three-stage operation.", "content": "Perforation of choledochus cyst with biliary peritonitis; report of a case submitted to a three-stage operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986070"}
{"pmid": "20986071", "title": "Report of an unusual case of mediastinal tumor.", "content": "Report of an unusual case of mediastinal tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986071"}
{"pmid": "20986072", "title": "Post-measles and post-mumps encephalitis.", "content": "Post-measles and post-mumps encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986072"}
{"pmid": "20986073", "title": "Filariasis and malaria on the campus.", "content": "Filariasis and malaria on the campus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986073"}
{"pmid": "20986074", "title": "Oxygen therapy.", "content": "Oxygen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986074"}
{"pmid": "20986075", "title": "The treatment of trimalleolar fractures of the ankle.", "content": "The treatment of trimalleolar fractures of the ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986075"}
{"pmid": "20986076", "title": "The control of haemorrhage at tonsillectomy.", "content": "The control of haemorrhage at tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986076"}
{"pmid": "20986077", "title": "Aetiology, investigation and treatment of leucorrhoea.", "content": "Aetiology, investigation and treatment of leucorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986077"}
{"pmid": "20986078", "title": "Clinical uses of the various insulins.", "content": "Clinical uses of the various insulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986078"}
{"pmid": "20986079", "title": "Effect of hesperidin and ascorbic acid on capillary fragility in rheumatoid arthritis; a preliminary report.", "content": "Effect of hesperidin and ascorbic acid on capillary fragility in rheumatoid arthritis; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986079"}
{"pmid": "20986105", "title": "Hematuria: its medical and surgical significance.", "content": "Hematuria: its medical and surgical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986105"}
{"pmid": "20986104", "title": "RHEUMATIC fever program in South Carolina.", "content": "RHEUMATIC fever program in South Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986104"}
{"pmid": "20986106", "title": "Comments on the diagnosis and management of gallbladder disease.", "content": "Comments on the diagnosis and management of gallbladder disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986106"}
{"pmid": "20986107", "title": "Ruptured abdominal aneurysm; case report.", "content": "Ruptured abdominal aneurysm; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986107"}
{"pmid": "20986099", "title": "Congenital malformations of the rectum and anus.", "content": "Congenital malformations of the rectum and anus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986099"}
{"pmid": "20986108", "title": "Medical administration as a career.", "content": "Medical administration as a career.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986108"}
{"pmid": "20986098", "title": "Status of the fenestration operation for otosclerosis; presentation of permanently improved cases.", "content": "Status of the fenestration operation for otosclerosis; presentation of permanently improved cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986098"}
{"pmid": "20986100", "title": "Latent subphrenic abscess.", "content": "Latent subphrenic abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986100"}
{"pmid": "20986101", "title": "Essays on biology of disease; peptic ulcer.", "content": "Essays on biology of disease; peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986101"}
{"pmid": "20986109", "title": "Acute benign dry pleurisy in the Middle East.", "content": "Acute benign dry pleurisy in the Middle East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986109"}
{"pmid": "20986102", "title": "Massive pulmonary embolism; based in part on a study of eighty-eight fatal cases.", "content": "Massive pulmonary embolism; based in part on a study of eighty-eight fatal cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986102"}
{"pmid": "20986110", "title": "Clinical trials of kemithal.", "content": "Clinical trials of kemithal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986110"}
{"pmid": "20986111", "title": "Clinical investigation of kemithal.", "content": "Clinical investigation of kemithal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986111"}
{"pmid": "20986112", "title": "Kemithal anaesthesia in thoracic operations.", "content": "Kemithal anaesthesia in thoracic operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986112"}
{"pmid": "20986103", "title": "Cutaneous manifestations of systemic disease.", "content": "Cutaneous manifestations of systemic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986103"}
{"pmid": "20986113", "title": "Lipodystrophy and hepatomegaly with diabetes, lipaemia, and other metabolic disturbances; a case throwing new light on the action of insulin. (concluded).", "content": "Lipodystrophy and hepatomegaly with diabetes, lipaemia, and other metabolic disturbances; a case throwing new light on the action of insulin. (concluded).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986113"}
{"pmid": "20986114", "title": "Epidemic epididymo-orchitis in Malta.", "content": "Epidemic epididymo-orchitis in Malta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986114"}
{"pmid": "20986115", "title": "Non-specific epididymitis.", "content": "Non-specific epididymitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986115"}
{"pmid": "20986116", "title": "Hyperplasia of seminal vesicle causing enuresis.", "content": "Hyperplasia of seminal vesicle causing enuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986116"}
{"pmid": "20986117", "title": "UNRRA's health campaign in Greece.", "content": "UNRRA's health campaign in Greece.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986117"}
{"pmid": "20986118", "title": "MEDICAL service in Australia.", "content": "MEDICAL service in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986118"}
{"pmid": "20986119", "title": "Fowler's position.", "content": "Fowler's position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986119"}
{"pmid": "20986120", "title": "Care of the chronic aged sick.", "content": "Care of the chronic aged sick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986120"}
{"pmid": "20986122", "title": "Crohn's disease; report of two cases.", "content": "Crohn's disease; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986122"}
{"pmid": "20986121", "title": "Segmental resection of lung for bronchiectasis.", "content": "Segmental resection of lung for bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986121"}
{"pmid": "20986123", "title": "Penicillin in chronic osteomyelitis.", "content": "Penicillin in chronic osteomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986123"}
{"pmid": "20986124", "title": "Chronic diarrhoea treated with folic acid.", "content": "Chronic diarrhoea treated with folic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986124"}
{"pmid": "20986125", "title": "Oedema in recovered prisoners-of-war.", "content": "Oedema in recovered prisoners-of-war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986125"}
{"pmid": "20986132", "title": "Studies in the control of scrub typhus.", "content": "Studies in the control of scrub typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986132"}
{"pmid": "20986133", "title": "Some remarks on psychotic ex-servicemen.", "content": "Some remarks on psychotic ex-servicemen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986133"}
{"pmid": "20986135", "title": "Indications for, and the care of, contact glasses.", "content": "Indications for, and the care of, contact glasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986135"}
{"pmid": "20986134", "title": "The modern treatment of puerperal sepsis.", "content": "The modern treatment of puerperal sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986134"}
{"pmid": "20986136", "title": "Some risks from new remedies in tropical disease.", "content": "Some risks from new remedies in tropical disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986136"}
{"pmid": "20986137", "title": "The infectious diseases service.", "content": "The infectious diseases service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986137"}
{"pmid": "20986139", "title": "An evaluation of physical methods of treatment in mental disease.", "content": "An evaluation of physical methods of treatment in mental disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986139"}
{"pmid": "20986138", "title": "The modern treatment, after-care and prognosis of pleurisy.", "content": "The modern treatment, after-care and prognosis of pleurisy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986138"}
{"pmid": "20986140", "title": "The rhesus factor in medicine.", "content": "The rhesus factor in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986140"}
{"pmid": "20986141", "title": "The treatment of uterine prolapse.", "content": "The treatment of uterine prolapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986141"}
{"pmid": "20986142", "title": "Sexual inversion and the English law.", "content": "Sexual inversion and the English law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986142"}
{"pmid": "20986143", "title": "Treatment of pneumonia.", "content": "Treatment of pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986143"}
{"pmid": "20986144", "title": "The prevention and treatment of complications in cataract surgery.", "content": "The prevention and treatment of complications in cataract surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986144"}
{"pmid": "20986145", "title": "Dacryocystitis and epiphora.", "content": "Dacryocystitis and epiphora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986145"}
{"pmid": "20986146", "title": "Headaches in women.", "content": "Headaches in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986146"}
{"pmid": "20986147", "title": "Headaches from the ophthalmic standpoint.", "content": "Headaches from the ophthalmic standpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986147"}
{"pmid": "20986148", "title": "The clinical value of a fundus examination.", "content": "The clinical value of a fundus examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986148"}
{"pmid": "20986149", "title": "Headaches from the oto-laryngological standpoint.", "content": "Headaches from the oto-laryngological standpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986149"}
{"pmid": "20986150", "title": "Treatment of pelvic conditions in women; use of a new device in physical therapy; a preliminary report.", "content": "Treatment of pelvic conditions in women; use of a new device in physical therapy; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986150"}
{"pmid": "20986151", "title": "The art of increasing and diminishing the bodily weight at will.", "content": "The art of increasing and diminishing the bodily weight at will.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986151"}
{"pmid": "20986152", "title": "The chemical brew of the brain.", "content": "The chemical brew of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986152"}
{"pmid": "20986153", "title": "Psychometric evaluation of sedatives.", "content": "Psychometric evaluation of sedatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986153"}
{"pmid": "20986154", "title": "Malignancies of the larynx; shall we employ surgery or radiotherapy?", "content": "Malignancies of the larynx; shall we employ surgery or radiotherapy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986154"}
{"pmid": "20986155", "title": "Cast treatment for severe burns of the extremities.", "content": "Cast treatment for severe burns of the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986155"}
{"pmid": "20986156", "title": "The small maternity hospital.", "content": "The small maternity hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986156"}
{"pmid": "20986157", "title": "Oxidase and aviation.", "content": "Oxidase and aviation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986157"}
{"pmid": "20986158", "title": "One hundred and forty-two operations for biliary disease from January 1, 1943 to January 1, 1946.", "content": "One hundred and forty-two operations for biliary disease from January 1, 1943 to January 1, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986158"}
{"pmid": "20986159", "title": "SURVIVALS for five to nine years of patients treated for cancer in the hospitals of Rochester, New York.", "content": "SURVIVALS for five to nine years of patients treated for cancer in the hospitals of Rochester, New York.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986159"}
{"pmid": "20986160", "title": "Doctor traces indigestion to non-calculous cholecystitis.", "content": "Doctor traces indigestion to non-calculous cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986160"}
{"pmid": "20986162", "title": "Early methods in the prevention of blindness.", "content": "Early methods in the prevention of blindness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986162"}
{"pmid": "20986161", "title": "How the neurotic soldier responds after discharge from hospitals.", "content": "How the neurotic soldier responds after discharge from hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986161"}
{"pmid": "20986163", "title": "Plastic portraits properly executed prolongs youth.", "content": "Plastic portraits properly executed prolongs youth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986163"}
{"pmid": "20986164", "title": "Treatment of urinary tract infections.", "content": "Treatment of urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986164"}
{"pmid": "20986165", "title": "The causes and the management of what is termed frigidity.", "content": "The causes and the management of what is termed frigidity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986165"}
{"pmid": "20986166", "title": "The ocular changes of primary diffuse toxic goitre; a review.", "content": "The ocular changes of primary diffuse toxic goitre; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986166"}
{"pmid": "20986167", "title": "Scrub typhus in Assam and Burma; a clinical study of 616 cases.", "content": "Scrub typhus in Assam and Burma; a clinical study of 616 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986167"}
{"pmid": "20986169", "title": "Compound, comminuted fractures of the skull in battle casualties.", "content": "Compound, comminuted fractures of the skull in battle casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986169"}
{"pmid": "20986168", "title": "The treatment of pneumococcic and staphylococcio meningitis with penicillin and sulfonamides; report of twenty cases.", "content": "The treatment of pneumococcic and staphylococcio meningitis with penicillin and sulfonamides; report of twenty cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986168"}
{"pmid": "20986170", "title": "Vertigo in hypothyroidism.", "content": "Vertigo in hypothyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986170"}
{"pmid": "20986171", "title": "The evaluation and management of recurrent headaches.", "content": "The evaluation and management of recurrent headaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986171"}
{"pmid": "20986173", "title": "Calyceal diverticulum.", "content": "Calyceal diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986173"}
{"pmid": "20986172", "title": "Blood dyscrasia with and without associated atypical lichen planus; report of four cases.", "content": "Blood dyscrasia with and without associated atypical lichen planus; report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986172"}
{"pmid": "20986174", "title": "Effect of antiluetic therapy on bundle branch block.", "content": "Effect of antiluetic therapy on bundle branch block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986174"}
{"pmid": "20986175", "title": "Section of the vagus nerves to the stomach in the treatment of gastroduodenal ulcer.", "content": "Section of the vagus nerves to the stomach in the treatment of gastroduodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986175"}
{"pmid": "20986177", "title": "Islet cell tumor of the pancreas; report of a case treated by local excision with complete recovery.", "content": "Islet cell tumor of the pancreas; report of a case treated by local excision with complete recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986177"}
{"pmid": "20986176", "title": "Multiple myeloma; report of a case.", "content": "Multiple myeloma; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986176"}
{"pmid": "20986178", "title": "Surgical approaches to bones and joints.", "content": "Surgical approaches to bones and joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986178"}
{"pmid": "20986179", "title": "Health bills pending in Congress.", "content": "Health bills pending in Congress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986179"}
{"pmid": "20986180", "title": "Involvement of the central nervous system in infectious mononucleosis; a report of two cases.", "content": "Involvement of the central nervous system in infectious mononucleosis; a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986180"}
{"pmid": "20986181", "title": "Fluorine and dental caries.", "content": "Fluorine and dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986181"}
{"pmid": "20986182", "title": "Diffuse plasma-cell myeloma.", "content": "Diffuse plasma-cell myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986182"}
{"pmid": "20986183", "title": "Adenocarcinoma of jejunum.", "content": "Adenocarcinoma of jejunum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986183"}
{"pmid": "20986184", "title": "The modern approach to the diagnosis and treatment of liver diseases.", "content": "The modern approach to the diagnosis and treatment of liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986184"}
{"pmid": "20986185", "title": "Hospitals and health insurance.", "content": "Hospitals and health insurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986185"}
{"pmid": "20986186", "title": "Prostatic surgery to today.", "content": "Prostatic surgery to today.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986186"}
{"pmid": "20986187", "title": "Surgical accidents of the female ureter.", "content": "Surgical accidents of the female ureter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986187"}
{"pmid": "20986188", "title": "Surgery of the spleen.", "content": "Surgery of the spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986188"}
{"pmid": "20986189", "title": "Caudal anesthesia in obstetrics.", "content": "Caudal anesthesia in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986189"}
{"pmid": "20986190", "title": "Principles versus mechanisms in surgery.", "content": "Principles versus mechanisms in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986190"}
{"pmid": "20986191", "title": "Role of roentgenography in intestinal obstruction.", "content": "Role of roentgenography in intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986191"}
{"pmid": "20986192", "title": "Ligation of femoral vein for thromboembolism.", "content": "Ligation of femoral vein for thromboembolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986192"}
{"pmid": "20986193", "title": "Scarlet fever prophylaxis with penicillin.", "content": "Scarlet fever prophylaxis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986193"}
{"pmid": "20986194", "title": "Rapid citrated blood transfusions.", "content": "Rapid citrated blood transfusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986194"}
{"pmid": "20986195", "title": "Public health and the treatment of early syphilis.", "content": "Public health and the treatment of early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986195"}
{"pmid": "20986196", "title": "Relapse during penicillin therapy of syphilis.", "content": "Relapse during penicillin therapy of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986196"}
{"pmid": "20986197", "title": "Light for head mirrors.", "content": "Light for head mirrors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986197"}
{"pmid": "20986198", "title": "Glycerite of hydrogen peroxide; a correlative review of laboratory and clinical data.", "content": "Glycerite of hydrogen peroxide; a correlative review of laboratory and clinical data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986198"}
{"pmid": "20986199", "title": "Tantalum cranioplasty.", "content": "Tantalum cranioplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986199"}
{"pmid": "20986200", "title": "Differential diagnosis between appendicitis and adnexal disease.", "content": "Differential diagnosis between appendicitis and adnexal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986200"}
{"pmid": "20986201", "title": "A case of concurrent encephalitis and acute infectious hepatitis.", "content": "A case of concurrent encephalitis and acute infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986201"}
{"pmid": "20986202", "title": "The Rh factor.", "content": "The Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986202"}
{"pmid": "20986203", "title": "Cystic fibrosis of the pancreas in an adult.", "content": "Cystic fibrosis of the pancreas in an adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986203"}
{"pmid": "20986204", "title": "Medical curiosities; tuberculosis treatment, 1891.", "content": "Medical curiosities; tuberculosis treatment, 1891.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986204"}
{"pmid": "20986205", "title": "The cross-eyed infant and the young child.", "content": "The cross-eyed infant and the young child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986205"}
{"pmid": "20986206", "title": "PROGRESS in digitalis therapy.", "content": "PROGRESS in digitalis therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986206"}
{"pmid": "20986208", "title": "NORMAL standards for nutritional state and growth.", "content": "NORMAL standards for nutritional state and growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986208"}
{"pmid": "20986207", "title": "PRESENT status of streptomycin.", "content": "PRESENT status of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986207"}
{"pmid": "20986209", "title": "ARACHNIDISM.", "content": "ARACHNIDISM.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986209"}
{"pmid": "20986232", "title": "Pseudoappendicitis rheumatica.", "content": "Pseudoappendicitis rheumatica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986232"}
{"pmid": "20986237", "title": "Gastric sarcoma.", "content": "Gastric sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986237"}
{"pmid": "20986244", "title": "Amebiasis.", "content": "Amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986244"}
{"pmid": "20986269", "title": "Pan-marrow hematopoiesis (L. casei factor) and splenic hematopenia; experimental and clinical studies.", "content": "Pan-marrow hematopoiesis (L. casei factor) and splenic hematopenia; experimental and clinical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986269"}
{"pmid": "20986270", "title": "The betatron and its medical application.", "content": "The betatron and its medical application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986270"}
{"pmid": "20986272", "title": "Multiple bile duct adenoma.", "content": "Multiple bile duct adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986272"}
{"pmid": "20986271", "title": "Ethylene glycol poisoning with suggestions for its treatment.", "content": "Ethylene glycol poisoning with suggestions for its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986271"}
{"pmid": "20986273", "title": "Pulmonary amoebiasis.", "content": "Pulmonary amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986273"}
{"pmid": "20986274", "title": "Intra-medullary ivory splint for an un-united fracture of the femur.", "content": "Intra-medullary ivory splint for an un-united fracture of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986274"}
{"pmid": "20986275", "title": "A case of haemoglobinuria following the administration of sulphapyridine.", "content": "A case of haemoglobinuria following the administration of sulphapyridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986275"}
{"pmid": "20986278", "title": "Inter-American training in public health.", "content": "Inter-American training in public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986278"}
{"pmid": "20986279", "title": "Growth and reproduction in the rat on diets of rice and beans.", "content": "Growth and reproduction in the rat on diets of rice and beans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986279"}
{"pmid": "20986280", "title": "Nutritional values of mixtures of polished rice, red kidney beans, chickpeas, and soybeans.", "content": "Nutritional values of mixtures of polished rice, red kidney beans, chickpeas, and soybeans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986280"}
{"pmid": "20986281", "title": "A throat culture survey of troops stationed in Puerto Rico.", "content": "A throat culture survey of troops stationed in Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986281"}
{"pmid": "20986282", "title": "Hematemesis nine years after splenectomy.", "content": "Hematemesis nine years after splenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986282"}
{"pmid": "20986337", "title": "The Wood light as an aid to the diagnosis of ringworm of the scalp and other dermatoses.", "content": "The Wood light as an aid to the diagnosis of ringworm of the scalp and other dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986337"}
{"pmid": "20986338", "title": "Acute respiratory diseases from the standpoint of the pediatrician.", "content": "Acute respiratory diseases from the standpoint of the pediatrician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986338"}
{"pmid": "20986339", "title": "Upper respiratory infection.", "content": "Upper respiratory infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986339"}
{"pmid": "20986340", "title": "Acute respiratory infections from the internist's viewpoint.", "content": "Acute respiratory infections from the internist's viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986340"}
{"pmid": "20986341", "title": "A functional approach to the diagnosis and treatment of static foot disorders.", "content": "A functional approach to the diagnosis and treatment of static foot disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986341"}
{"pmid": "20986342", "title": "Surgical cure of acne rosacea and rhinophyma.", "content": "Surgical cure of acne rosacea and rhinophyma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986342"}
{"pmid": "20986343", "title": "Disorders of the heart beat.", "content": "Disorders of the heart beat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986343"}
{"pmid": "20986344", "title": "Backache as an initial symptom in rheumatic fever.", "content": "Backache as an initial symptom in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986344"}
{"pmid": "20986345", "title": "Preliminary studies of gamma globulins as determined by chemical methods.", "content": "Preliminary studies of gamma globulins as determined by chemical methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986345"}
{"pmid": "20986346", "title": "Chronic haemolytic icterus resembling acholuric jaundice occurring in an African native.", "content": "Chronic haemolytic icterus resembling acholuric jaundice occurring in an African native.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986346"}
{"pmid": "20986347", "title": "Fractures of the skull involving the frontal air sinuses due to localised violence; a study of 30 cases.", "content": "Fractures of the skull involving the frontal air sinuses due to localised violence; a study of 30 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986347"}
{"pmid": "20986350", "title": "ASTROLOGY, drugs and medicine.", "content": "ASTROLOGY, drugs and medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986350"}
{"pmid": "20986349", "title": "Schistosomiasis in southern Africa in its relation to the pollution of river-pools.", "content": "Schistosomiasis in southern Africa in its relation to the pollution of river-pools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986349"}
{"pmid": "20986351", "title": "Fenestration for otosclerosis.", "content": "Fenestration for otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986351"}
{"pmid": "20986353", "title": "PENTACRESOL: a virucidal antiseptic.", "content": "PENTACRESOL: a virucidal antiseptic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986353"}
{"pmid": "20986352", "title": "NUTRITION in pregnancy.", "content": "NUTRITION in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986352"}
{"pmid": "20986354", "title": "THIOURACIL in the management of Graves' disease.", "content": "THIOURACIL in the management of Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986354"}
{"pmid": "20986356", "title": "STRUCTURE and physiology of dentin and enamel.", "content": "STRUCTURE and physiology of dentin and enamel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986356"}
{"pmid": "20986355", "title": "ANATOMY of a tooth.", "content": "ANATOMY of a tooth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986355"}
{"pmid": "20986357", "title": "OBSTETRICAL USE of ergot alkaloids.", "content": "OBSTETRICAL USE of ergot alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986357"}
{"pmid": "20986358", "title": "STREPTOMYCIN in experimental tuberculosis.", "content": "STREPTOMYCIN in experimental tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986358"}
{"pmid": "20986370", "title": "Ulcerative colitis in children; a psychiatric evaluation.", "content": "Ulcerative colitis in children; a psychiatric evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986370"}
{"pmid": "20986371", "title": "Personality aspects of skin diseases.", "content": "Personality aspects of skin diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986371"}
{"pmid": "20986372", "title": "Neurofibromatosis with congenital defect in wall of orbit; report of 5 cases.", "content": "Neurofibromatosis with congenital defect in wall of orbit; report of 5 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986372"}
{"pmid": "20986373", "title": "Roentgen therapy; treatment of malignant tumors of testis.", "content": "Roentgen therapy; treatment of malignant tumors of testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986373"}
{"pmid": "20986374", "title": "Roentgen therapy in acute mastitis.", "content": "Roentgen therapy in acute mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986374"}
{"pmid": "20986375", "title": "Local health service; a proposal of the American Public Health Association.", "content": "Local health service; a proposal of the American Public Health Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986375"}
{"pmid": "20986376", "title": "Gastritis.", "content": "Gastritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986376"}
{"pmid": "20986377", "title": "External eye diseases; case reports.", "content": "External eye diseases; case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986377"}
{"pmid": "20986378", "title": "Bilateral symmetrical infiltration over the superior rectus muscles in lymphatic leukemia.", "content": "Bilateral symmetrical infiltration over the superior rectus muscles in lymphatic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986378"}
{"pmid": "20986379", "title": "Chloroma, 3 year old male.", "content": "Chloroma, 3 year old male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986379"}
{"pmid": "20986380", "title": "Traumatic dislocation and fracture dislocation of the hip joint.", "content": "Traumatic dislocation and fracture dislocation of the hip joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986380"}
{"pmid": "20986381", "title": "Vitamin A in pregnancy.", "content": "Vitamin A in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986381"}
{"pmid": "20986382", "title": "Suspect rheumatic fever.", "content": "Suspect rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986382"}
{"pmid": "20986383", "title": "Complicated thrombophlebitis.", "content": "Complicated thrombophlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986383"}
{"pmid": "20986384", "title": "Complicated hyperthyroidism.", "content": "Complicated hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986384"}
{"pmid": "20986385", "title": "Anesthesia for open chest surgery.", "content": "Anesthesia for open chest surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986385"}
{"pmid": "20986386", "title": "Actinomycosis.", "content": "Actinomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986386"}
{"pmid": "20986388", "title": "Some newer concepts of the natural derivatives of hemoglobin and related compounds.", "content": "Some newer concepts of the natural derivatives of hemoglobin and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986388"}
{"pmid": "20986387", "title": "The need of physical therapy in pediatrics.", "content": "The need of physical therapy in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986387"}
{"pmid": "20986389", "title": "Hospitals report 1943-44, 1944-45.", "content": "Hospitals report 1943-44, 1944-45.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986389"}
{"pmid": "20986390", "title": "Synovioma.", "content": "Synovioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986390"}
{"pmid": "20986391", "title": "Toxoplasmosis.", "content": "Toxoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986391"}
{"pmid": "20986392", "title": "Neoplastic biliary obstruction.", "content": "Neoplastic biliary obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986392"}
{"pmid": "20986393", "title": "Facial injuries.", "content": "Facial injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986393"}
{"pmid": "20986394", "title": "Cholangiolitic cirrhosis.", "content": "Cholangiolitic cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986394"}
{"pmid": "20986395", "title": "Carcinoma of the bronchus.", "content": "Carcinoma of the bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986395"}
{"pmid": "20986396", "title": "Pneumonitis.", "content": "Pneumonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986396"}
{"pmid": "20986397", "title": "Helium in the treatment of asthma.", "content": "Helium in the treatment of asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986397"}
{"pmid": "20986398", "title": "Stainless steel wire suture technique in thoracic surgery.", "content": "Stainless steel wire suture technique in thoracic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986398"}
{"pmid": "20986399", "title": "Spontaneous perforation of the oesophagus; review of the literature and report of three new cases.", "content": "Spontaneous perforation of the oesophagus; review of the literature and report of three new cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986399"}
{"pmid": "20986400", "title": "The use of antibiotics in the treatment of bacterial infections.", "content": "The use of antibiotics in the treatment of bacterial infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986400"}
{"pmid": "20986401", "title": "RESEARCH on visual problems encountered in naval operations.", "content": "RESEARCH on visual problems encountered in naval operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986401"}
{"pmid": "20986402", "title": "RESEARCH on auditory problems presented by naval operations.", "content": "RESEARCH on auditory problems presented by naval operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986402"}
{"pmid": "20986403", "title": "NUTRITION.", "content": "NUTRITION.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986403"}
{"pmid": "20986404", "title": "PROTECTION of personnel from excessive noise.", "content": "PROTECTION of personnel from excessive noise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986404"}
{"pmid": "20986406", "title": "IMMERSION foot.", "content": "IMMERSION foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986406"}
{"pmid": "20986407", "title": "TRAUMATIC and burn shock.", "content": "TRAUMATIC and burn shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986407"}
{"pmid": "20986405", "title": "LIFE saving equipment.", "content": "LIFE saving equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986405"}
{"pmid": "20986408", "title": "PROTECTIVE clothing and equipment.", "content": "PROTECTIVE clothing and equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986408"}
{"pmid": "20986409", "title": "OPTICIAN service.", "content": "OPTICIAN service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986409"}
{"pmid": "20986410", "title": "CARBON monoxide hazards.", "content": "CARBON monoxide hazards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986410"}
{"pmid": "20986411", "title": "GLASSLESS eye shields.", "content": "GLASSLESS eye shields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986411"}
{"pmid": "20986412", "title": "SEASICKNESS.", "content": "SEASICKNESS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986412"}
{"pmid": "20986413", "title": "Small pox among U.S. Army forces in Korea.", "content": "Small pox among U.S. Army forces in Korea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986413"}
{"pmid": "20986415", "title": "Study of combat fatigue cases returned to front-line duty.", "content": "Study of combat fatigue cases returned to front-line duty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986415"}
{"pmid": "20986414", "title": "Report of studies on venereal disease.", "content": "Report of studies on venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986414"}
{"pmid": "20986416", "title": "Helminth infections among Manila children, one month to ten years old.", "content": "Helminth infections among Manila children, one month to ten years old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986416"}
{"pmid": "20986418", "title": "Nutritional evaluation of the ration.", "content": "Nutritional evaluation of the ration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986418"}
{"pmid": "20986417", "title": "Electrocardiographic changes in beri-beri heart disease.", "content": "Electrocardiographic changes in beri-beri heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986417"}
{"pmid": "20986419", "title": "Notes on venereal disease control.", "content": "Notes on venereal disease control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986419"}
{"pmid": "20986420", "title": "Multiple fractures of the facial bones; report of a case.", "content": "Multiple fractures of the facial bones; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986420"}
{"pmid": "20986421", "title": "Stool survey of the Seventh Infantry Division.", "content": "Stool survey of the Seventh Infantry Division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986421"}
{"pmid": "20986426", "title": "Blood levels of calcium and inorganic phosphorus in Hemford cattle.", "content": "Blood levels of calcium and inorganic phosphorus in Hemford cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986426"}
{"pmid": "20986427", "title": "SCIENTIFIC and industrial research in Great Britain.", "content": "SCIENTIFIC and industrial research in Great Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986427"}
{"pmid": "20986428", "title": "Ionic permeability of skeletal muscle fibres.", "content": "Ionic permeability of skeletal muscle fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986428"}
{"pmid": "20986429", "title": "British prehistoric archaeology: recent aims, methods and results.", "content": "British prehistoric archaeology: recent aims, methods and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986429"}
{"pmid": "20986430", "title": "Physiology of fertilization.", "content": "Physiology of fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986430"}
{"pmid": "20986431", "title": "RESEARCH into the common cold.", "content": "RESEARCH into the common cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986431"}
{"pmid": "20986432", "title": "Musa fehi, the indigenous banana of Fiji.", "content": "Musa fehi, the indigenous banana of Fiji.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986432"}
{"pmid": "20986433", "title": "Changes in the contents of acetylcholine in nervous tissue under the influence of constant current.", "content": "Changes in the contents of acetylcholine in nervous tissue under the influence of constant current.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986433"}
{"pmid": "20986435", "title": "Luminosity curve of trichromats.", "content": "Luminosity curve of trichromats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986435"}
{"pmid": "20986434", "title": "Synergic effect of ascorbic acid and riboflavin on penicillin in vitro.", "content": "Synergic effect of ascorbic acid and riboflavin on penicillin in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986434"}
{"pmid": "20986437", "title": "RADIATION and living cells.", "content": "RADIATION and living cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986437"}
{"pmid": "20986436", "title": "Planck's radiation formula.", "content": "Planck's radiation formula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986436"}
{"pmid": "20986438", "title": "Chemistry of the Feulgen and Dische nucleal reactions.", "content": "Chemistry of the Feulgen and Dische nucleal reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986438"}
{"pmid": "20986439", "title": "Ant gynandromorphs and other mosaics.", "content": "Ant gynandromorphs and other mosaics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986439"}
{"pmid": "20986441", "title": "MICROBIOLOGICAL assays.", "content": "MICROBIOLOGICAL assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986441"}
{"pmid": "20986442", "title": "YEAST fermentation method for the determination of thiamine.", "content": "YEAST fermentation method for the determination of thiamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986442"}
{"pmid": "20986443", "title": "MICROBIOLOGICAL assay for riboflavin.", "content": "MICROBIOLOGICAL assay for riboflavin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986443"}
{"pmid": "20986444", "title": "MICROBIOLOGICAL assay for nicotinic acid.", "content": "MICROBIOLOGICAL assay for nicotinic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986444"}
{"pmid": "20986445", "title": "MICROBIOLOGICAL assay for biotin.", "content": "MICROBIOLOGICAL assay for biotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986445"}
{"pmid": "20986446", "title": "MICROBIOLOGICAL assay for pantothenic acid.", "content": "MICROBIOLOGICAL assay for pantothenic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986446"}
{"pmid": "20986447", "title": "MICROBIOLOGICAL assay for folic acid.", "content": "MICROBIOLOGICAL assay for folic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986447"}
{"pmid": "20986448", "title": "MICROBIOLOGICAL assay for pyridoxine.", "content": "MICROBIOLOGICAL assay for pyridoxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986448"}
{"pmid": "20986449", "title": "HOW life begins.", "content": "HOW life begins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986449"}
{"pmid": "20986450", "title": "SUDS in action.", "content": "SUDS in action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986450"}
{"pmid": "20986451", "title": "SEEING in the dark.", "content": "SEEING in the dark.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986451"}
{"pmid": "20986452", "title": "PENICILLIN: is it on the skids?", "content": "PENICILLIN: is it on the skids?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986452"}
{"pmid": "20986453", "title": "Physical thinking and social problems.", "content": "Physical thinking and social problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986453"}
{"pmid": "20986455", "title": "Pectoral girdles vs. hyobranchia in the snake genera Liotyphlops and Anomalepis.", "content": "Pectoral girdles vs. hyobranchia in the snake genera Liotyphlops and Anomalepis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986455"}
{"pmid": "20986454", "title": "An intestinal antiseptic, 2-sulfanilamido-5-carboxythiazole.", "content": "An intestinal antiseptic, 2-sulfanilamido-5-carboxythiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986454"}
{"pmid": "20986456", "title": "Interrelations between choline, betaine, and methionine.", "content": "Interrelations between choline, betaine, and methionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986456"}
{"pmid": "20986457", "title": "A modification of the ergograph.", "content": "A modification of the ergograph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986457"}
{"pmid": "20986458", "title": "The metric system and the historical record.", "content": "The metric system and the historical record.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986458"}
{"pmid": "20986459", "title": "Death-rate study on a high molecular quaternary ammonium compound with Bacillus metiens.", "content": "Death-rate study on a high molecular quaternary ammonium compound with Bacillus metiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986459"}
{"pmid": "20986461", "title": "Tissue metabolism studies on bone marrow.", "content": "Tissue metabolism studies on bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986461"}
{"pmid": "20986460", "title": "Aspergillus or what?", "content": "Aspergillus or what?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986460"}
{"pmid": "20986462", "title": "Psychosomatic medicine.", "content": "Psychosomatic medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986462"}
{"pmid": "20986463", "title": "The folklore of a small town.", "content": "The folklore of a small town.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986463"}
{"pmid": "20986484", "title": "Motivation of crime.", "content": "Motivation of crime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986484"}
{"pmid": "20986485", "title": "Scientific proof and relations of law and medicine; simulation of nervous and mental disease.", "content": "Scientific proof and relations of law and medicine; simulation of nervous and mental disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986485"}
{"pmid": "20986486", "title": "Integration of medical science and sociology.", "content": "Integration of medical science and sociology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986486"}
{"pmid": "20986487", "title": "Sexual offenders.", "content": "Sexual offenders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986487"}
{"pmid": "20986488", "title": "Medicolegal aspects of spinal cord injuries.", "content": "Medicolegal aspects of spinal cord injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986488"}
{"pmid": "20986489", "title": "Ruptured intervertebral disk.", "content": "Ruptured intervertebral disk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986489"}
{"pmid": "20986490", "title": "The spastic child.", "content": "The spastic child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986490"}
{"pmid": "20986491", "title": "The care of cerebral palsy.", "content": "The care of cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986491"}
{"pmid": "20986492", "title": "The public health aspect of cerebral palsy.", "content": "The public health aspect of cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986492"}
{"pmid": "20986493", "title": "Speech Clinic at the Children's Memorial Hospital.", "content": "Speech Clinic at the Children's Memorial Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986493"}
{"pmid": "20986495", "title": "Psychiatry in the general practice of medicine.", "content": "Psychiatry in the general practice of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986495"}
{"pmid": "20986496", "title": "DDT.", "content": "DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986496"}
{"pmid": "20986497", "title": "The young child in hospital; careful handling prevents future mental disturbance.", "content": "The young child in hospital; careful handling prevents future mental disturbance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986497"}
{"pmid": "20986498", "title": "The mock accident in first-aid training; burns of the extremities.", "content": "The mock accident in first-aid training; burns of the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986498"}
{"pmid": "20986499", "title": "Structure and diseases of the nose and throat; anatomy and physiology of throat.", "content": "Structure and diseases of the nose and throat; anatomy and physiology of throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986499"}
{"pmid": "20986500", "title": "Obstetrical aspects of infertility.", "content": "Obstetrical aspects of infertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986500"}
{"pmid": "20986501", "title": "Ocular sequelae of head injuries.", "content": "Ocular sequelae of head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986501"}
{"pmid": "20986502", "title": "Pernicious anaemia.", "content": "Pernicious anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986502"}
{"pmid": "20986503", "title": "RODENT ulcer.", "content": "RODENT ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986503"}
{"pmid": "20986504", "title": "Early failure of breast feeding.", "content": "Early failure of breast feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986504"}
{"pmid": "20986505", "title": "Curare; a revolution in anaesthesia.", "content": "Curare; a revolution in anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986505"}
{"pmid": "20986506", "title": "Post-menopausal bleeding; its causes and treatment.", "content": "Post-menopausal bleeding; its causes and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986506"}
{"pmid": "20986507", "title": "The nurse and her skin.", "content": "The nurse and her skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986507"}
{"pmid": "20986508", "title": "The value of educational psychology; teaching to think.", "content": "The value of educational psychology; teaching to think.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986508"}
{"pmid": "20986509", "title": "Pre- and post-operative treatment of gall-bladder cases.", "content": "Pre- and post-operative treatment of gall-bladder cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986509"}
{"pmid": "20986510", "title": "Understanding the patient.", "content": "Understanding the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986510"}
{"pmid": "20986511", "title": "Camp values for all children.", "content": "Camp values for all children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986511"}
{"pmid": "20986512", "title": "The health officer's job.", "content": "The health officer's job.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986512"}
{"pmid": "20986513", "title": "Gamma globulin in measles prophylaxis.", "content": "Gamma globulin in measles prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986513"}
{"pmid": "20986514", "title": "Rheumatic fever; etiology, epidemiology, and prevalence.", "content": "Rheumatic fever; etiology, epidemiology, and prevalence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986514"}
{"pmid": "20986515", "title": "Public health nursing in a State medical care program.", "content": "Public health nursing in a State medical care program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986515"}
{"pmid": "20986516", "title": "Incipient pannus as a sign of the primary corneal infection of trachoma and as an important criterion for the early diagnosis of the disease.", "content": "Incipient pannus as a sign of the primary corneal infection of trachoma and as an important criterion for the early diagnosis of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986516"}
{"pmid": "20986517", "title": "Exophthalmic ophthalmoplegia and its relation to thyrotoxicosis.", "content": "Exophthalmic ophthalmoplegia and its relation to thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986517"}
{"pmid": "20986518", "title": "Belgian ophthalmology during the war.", "content": "Belgian ophthalmology during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986518"}
{"pmid": "20986519", "title": "Oxycephaly associated with Klippel-Feil syndrome and other skeletal defects.", "content": "Oxycephaly associated with Klippel-Feil syndrome and other skeletal defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986519"}
{"pmid": "20986520", "title": "Penicillin in gonococcic conjunctivitis; its use in 30 cases, compared with the sulfonamides in 173 cases.", "content": "Penicillin in gonococcic conjunctivitis; its use in 30 cases, compared with the sulfonamides in 173 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986520"}
{"pmid": "20986521", "title": "Oculoglandular tularemia; report of three cases with unusual contacts.", "content": "Oculoglandular tularemia; report of three cases with unusual contacts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986521"}
{"pmid": "20986522", "title": "Angioma of the retina; report of two cases with fundus photographs.", "content": "Angioma of the retina; report of two cases with fundus photographs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986522"}
{"pmid": "20986523", "title": "Amblyopia ex anopsia in the Armed Forces.", "content": "Amblyopia ex anopsia in the Armed Forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986523"}
{"pmid": "20986524", "title": "Detergents or wetting agents; physical and chemical characteristics.", "content": "Detergents or wetting agents; physical and chemical characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986524"}
{"pmid": "20986525", "title": "Meningococcic keratoconjunctivitis; report of a case treated with penicillin.", "content": "Meningococcic keratoconjunctivitis; report of a case treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986525"}
{"pmid": "20986526", "title": "Use of penicillin in acute dacryocystitis.", "content": "Use of penicillin in acute dacryocystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986526"}
{"pmid": "20986527", "title": "Individually made acrylic moist-chamber spectacles and pinhole glasses.", "content": "Individually made acrylic moist-chamber spectacles and pinhole glasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986527"}
{"pmid": "20986528", "title": "Syntropan as a mydriatic.", "content": "Syntropan as a mydriatic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986528"}
{"pmid": "20986529", "title": "Screening technique for eye defects in the Army.", "content": "Screening technique for eye defects in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986529"}
{"pmid": "20986530", "title": "Techniques for screening eye defects among industrial workers.", "content": "Techniques for screening eye defects among industrial workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986530"}
{"pmid": "20986531", "title": "Mass examination of school children.", "content": "Mass examination of school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986531"}
{"pmid": "20986532", "title": "Ectopia lentis.", "content": "Ectopia lentis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986532"}
{"pmid": "20986535", "title": "Conservation of lid margins during blepharoplasty.", "content": "Conservation of lid margins during blepharoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986535"}
{"pmid": "20986534", "title": "Cataract due to rubella in the mother.", "content": "Cataract due to rubella in the mother.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986534"}
{"pmid": "20986536", "title": "Some factors in the examination of astigmatism.", "content": "Some factors in the examination of astigmatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986536"}
{"pmid": "20986533", "title": "Sympathetic ophthalmia.", "content": "Sympathetic ophthalmia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986533"}
{"pmid": "20986537", "title": "An evaluation of aniseikonia after twelve years.", "content": "An evaluation of aniseikonia after twelve years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986537"}
{"pmid": "20986538", "title": "A plea for better instruction in perimetry.", "content": "A plea for better instruction in perimetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986538"}
{"pmid": "20986540", "title": "An analysis of reading progress in relation to vision.", "content": "An analysis of reading progress in relation to vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986540"}
{"pmid": "20986539", "title": "The Eye Bank for Sight Restoration, Inc.", "content": "The Eye Bank for Sight Restoration, Inc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986539"}
{"pmid": "20986541", "title": "A physiological unit of accommodation.", "content": "A physiological unit of accommodation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986541"}
{"pmid": "20986542", "title": "Orthoptics and visual training; some physiological, psychological and educational aspects.", "content": "Orthoptics and visual training; some physiological, psychological and educational aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986542"}
{"pmid": "20986543", "title": "Application of telescopic and microscopic spectacles in subnormal vision.", "content": "Application of telescopic and microscopic spectacles in subnormal vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986543"}
{"pmid": "20986544", "title": "Subjective testing.", "content": "Subjective testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986544"}
{"pmid": "20986546", "title": "Experimental histological studies on the labyrinth; anaphylaxis.", "content": "Experimental histological studies on the labyrinth; anaphylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986546"}
{"pmid": "20986547", "title": "Local treatment of maxillary sinusitis with alfasol.", "content": "Local treatment of maxillary sinusitis with alfasol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986547"}
{"pmid": "20986548", "title": "The demaskator; an instrument for the unmasking of shammed unilateral deafness.", "content": "The demaskator; an instrument for the unmasking of shammed unilateral deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986548"}
{"pmid": "20986549", "title": "On diagnosis and treatment of air-filled brain abscess.", "content": "On diagnosis and treatment of air-filled brain abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986549"}
{"pmid": "20986551", "title": "Complications in the ear, nose and throat in infectious mononucleosis.", "content": "Complications in the ear, nose and throat in infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986551"}
{"pmid": "20986550", "title": "Cryptogenetic cerebrospinal rhinorrhea.", "content": "Cryptogenetic cerebrospinal rhinorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986550"}
{"pmid": "20986553", "title": "Heterotopic tumors with an intestinal mucous membrane structure in the nasal cavity.", "content": "Heterotopic tumors with an intestinal mucous membrane structure in the nasal cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986553"}
{"pmid": "20986552", "title": "Akustisches Trauma and Funktion des Innenohres.", "content": "Akustisches Trauma and Funktion des Innenohres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986552"}
{"pmid": "20986554", "title": "Congenital cysts of the oesophagus.", "content": "Congenital cysts of the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986554"}
{"pmid": "20986555", "title": "Speech reception in relation to pattern of pure tone loss.", "content": "Speech reception in relation to pattern of pure tone loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986555"}
{"pmid": "20986556", "title": "A test of lip reading ability.", "content": "A test of lip reading ability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986556"}
{"pmid": "20986557", "title": "Hypnosis in a system of therapy for stutterers.", "content": "Hypnosis in a system of therapy for stutterers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986557"}
{"pmid": "20986558", "title": "Infant speech; vowel and consonant frequency.", "content": "Infant speech; vowel and consonant frequency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986558"}
{"pmid": "20986560", "title": "Metropolitan speech correction.", "content": "Metropolitan speech correction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986560"}
{"pmid": "20986559", "title": "The type-token ratio applied to infant speech sounds.", "content": "The type-token ratio applied to infant speech sounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986559"}
{"pmid": "20986561", "title": "Is is not the verb for aphasia.", "content": "Is is not the verb for aphasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986561"}
{"pmid": "20986562", "title": "Comments on testing aphasics in the speech clinic.", "content": "Comments on testing aphasics in the speech clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986562"}
{"pmid": "20986563", "title": "Linguistic problems of brain-injured servicemen.", "content": "Linguistic problems of brain-injured servicemen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986563"}
{"pmid": "20986564", "title": "Rehabilitation of aphasics in an Army hospital.", "content": "Rehabilitation of aphasics in an Army hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986564"}
{"pmid": "20986566", "title": "Studies on the Vi agglutination test for the detection of typhoid carriers.", "content": "Studies on the Vi agglutination test for the detection of typhoid carriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986566"}
{"pmid": "20986567", "title": "Thiouracil granulocytopenia and agranulocytosis; prognostic value of sternal marrow examination.", "content": "Thiouracil granulocytopenia and agranulocytosis; prognostic value of sternal marrow examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986567"}
{"pmid": "20986568", "title": "Notes on the pathogenesis of congenital hemolytic disease (erythroblastosis fetalis).", "content": "Notes on the pathogenesis of congenital hemolytic disease (erythroblastosis fetalis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986568"}
{"pmid": "20986569", "title": "Endocardial sclerosis in infants and children.", "content": "Endocardial sclerosis in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986569"}
{"pmid": "20986570", "title": "Multiple primary carcinomas of the kidney and bladder.", "content": "Multiple primary carcinomas of the kidney and bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986570"}
{"pmid": "20986571", "title": "Charts for determining the percentage variation of total leucocyte counts.", "content": "Charts for determining the percentage variation of total leucocyte counts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986571"}
{"pmid": "20986572", "title": "Copper sulfate method for hemoglobin determination in blood donors.", "content": "Copper sulfate method for hemoglobin determination in blood donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986572"}
{"pmid": "20986573", "title": "Gastric juice; simple methods for quantitative determination of protein digestion and pepsin values.", "content": "Gastric juice; simple methods for quantitative determination of protein digestion and pepsin values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986573"}
{"pmid": "20986574", "title": "Amylase in diabetics or a technical error.", "content": "Amylase in diabetics or a technical error.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986574"}
{"pmid": "20986575", "title": "A modified staining technic for thick drop preparations.", "content": "A modified staining technic for thick drop preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986575"}
{"pmid": "20986576", "title": "Test for boric acid as a preservative in milk.", "content": "Test for boric acid as a preservative in milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986576"}
{"pmid": "20986577", "title": "A new reagent for the qualitative detection of albumin in urine.", "content": "A new reagent for the qualitative detection of albumin in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986577"}
{"pmid": "20986578", "title": "A simple sharpener for microtome blades.", "content": "A simple sharpener for microtome blades.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986578"}
{"pmid": "20986579", "title": "Yolk sac cultivation of Leishmania from tissue and culture.", "content": "Yolk sac cultivation of Leishmania from tissue and culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986579"}
{"pmid": "20986580", "title": "Estimation of red blood cell count from hematocrit.", "content": "Estimation of red blood cell count from hematocrit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986580"}
{"pmid": "20986581", "title": "The patient and the medical technologist.", "content": "The patient and the medical technologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986581"}
{"pmid": "20986582", "title": "Changes in the central incisors of hypophysectomized female rats after different postoperative periods.", "content": "Changes in the central incisors of hypophysectomized female rats after different postoperative periods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986582"}
{"pmid": "20986583", "title": "Renal lesions in portal cirrhosis.", "content": "Renal lesions in portal cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986583"}
{"pmid": "20986584", "title": "Transitory pulmonary infiltrations (Loeffler's syndrome) in rabbits.", "content": "Transitory pulmonary infiltrations (Loeffler's syndrome) in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986584"}
{"pmid": "20986585", "title": "Adrenal hemorrhages in meningococcic sepsis.", "content": "Adrenal hemorrhages in meningococcic sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986585"}
{"pmid": "20986586", "title": "Radio-iodine autography in studies of human goitrous thyroid glands.", "content": "Radio-iodine autography in studies of human goitrous thyroid glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986586"}
{"pmid": "20986587", "title": "Hepatic and renal necrosis in alloxan diabetes of rabbits.", "content": "Hepatic and renal necrosis in alloxan diabetes of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986587"}
{"pmid": "20986588", "title": "Heart weight; the effect of tuberculosis on heart weight.", "content": "Heart weight; the effect of tuberculosis on heart weight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986588"}
{"pmid": "20986589", "title": "Genesis of aortic perforation secondary to carcinoma of the esophagus; report of observations in two cases.", "content": "Genesis of aortic perforation secondary to carcinoma of the esophagus; report of observations in two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986589"}
{"pmid": "20986590", "title": "Enteritis caused by Salmonella suipestifer with secondary moniliasis.", "content": "Enteritis caused by Salmonella suipestifer with secondary moniliasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986590"}
{"pmid": "20986591", "title": "Primary carcinoma of the liver of a dog.", "content": "Primary carcinoma of the liver of a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986591"}
{"pmid": "20986592", "title": "Hemopericardium from pericardial metastatic carcinoma.", "content": "Hemopericardium from pericardial metastatic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986592"}
{"pmid": "20986593", "title": "Teratoma of pineal gland with choriocarcinoma and rhabdomyosarcoma.", "content": "Teratoma of pineal gland with choriocarcinoma and rhabdomyosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986593"}
{"pmid": "20986594", "title": "A portable exhibit case.", "content": "A portable exhibit case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986594"}
{"pmid": "20986595", "title": "Improved methods for demonstrating amyloid in paraffin sections.", "content": "Improved methods for demonstrating amyloid in paraffin sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986595"}
{"pmid": "20986600", "title": "Bone marrow infusion and its complications.", "content": "Bone marrow infusion and its complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986600"}
{"pmid": "20986601", "title": "Congenital mediastinal cysts of foregut origin.", "content": "Congenital mediastinal cysts of foregut origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986601"}
{"pmid": "20986602", "title": "Scarlet fever among Pueblo Indians; observations on susceptibility and occurrence.", "content": "Scarlet fever among Pueblo Indians; observations on susceptibility and occurrence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986602"}
{"pmid": "20986603", "title": "Causes of prematurity; influence of uterine bleeding on the incidence of prematurity.", "content": "Causes of prematurity; influence of uterine bleeding on the incidence of prematurity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986603"}
{"pmid": "20986604", "title": "New type of familial congenital chronic hemolytic anemia.", "content": "New type of familial congenital chronic hemolytic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986604"}
{"pmid": "20986605", "title": "Treatment of infantile congenital syphilis with penicillin.", "content": "Treatment of infantile congenital syphilis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986605"}
{"pmid": "20986606", "title": "Sarcoidosis (Besnier-Boeck-Schaumann's disease); report of a case in a child simulating Still's disease.", "content": "Sarcoidosis (Besnier-Boeck-Schaumann's disease); report of a case in a child simulating Still's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986606"}
{"pmid": "20986607", "title": "Congenital hemihypertrophy; report of a case with postmortem observations.", "content": "Congenital hemihypertrophy; report of a case with postmortem observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986607"}
{"pmid": "20986608", "title": "Relationship of pediatrics and psychiatry.", "content": "Relationship of pediatrics and psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986608"}
{"pmid": "20986620", "title": "Rheumatic heart disease.", "content": "Rheumatic heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986620"}
{"pmid": "20986621", "title": "Social factors in the treatment of rheumatic fever.", "content": "Social factors in the treatment of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986621"}
{"pmid": "20986623", "title": "Still's disease.", "content": "Still's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986623"}
{"pmid": "20986622", "title": "Chronic constrictive pericarditis; report of the medical and surgical aspects of a case.", "content": "Chronic constrictive pericarditis; report of the medical and surgical aspects of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986622"}
{"pmid": "20986624", "title": "Lipochondrodystrophy.", "content": "Lipochondrodystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986624"}
{"pmid": "20986625", "title": "The successful use of oral penicillin in the treatment of subacute bacterial endocarditis; case report.", "content": "The successful use of oral penicillin in the treatment of subacute bacterial endocarditis; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986625"}
{"pmid": "20986626", "title": "Macrocytic anemia treated with folic acid.", "content": "Macrocytic anemia treated with folic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986626"}
{"pmid": "20986627", "title": "Sudden death from coronary insufficiency; report of a case in an infant.", "content": "Sudden death from coronary insufficiency; report of a case in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986627"}
{"pmid": "20986628", "title": "Congenital aneurysm of the basilar artery, ruptured.", "content": "Congenital aneurysm of the basilar artery, ruptured.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986628"}
{"pmid": "20986630", "title": "A sífilis infantil adquirida.", "content": "A sífilis infantil adquirida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986630"}
{"pmid": "20986639", "title": "The thickness of the skin and subcutaneous tissue by age and sex in childhood.", "content": "The thickness of the skin and subcutaneous tissue by age and sex in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986639"}
{"pmid": "20986640", "title": "A fifteen-year study of prematurity; from the standpoint of incidence, mortality, and survival.", "content": "A fifteen-year study of prematurity; from the standpoint of incidence, mortality, and survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986640"}
{"pmid": "20986641", "title": "The crying of newly born babies; a follow-up study after additional nursing care had been provided.", "content": "The crying of newly born babies; a follow-up study after additional nursing care had been provided.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986641"}
{"pmid": "20986642", "title": "Intracisternal penicillin; observations of its effect on dogs.", "content": "Intracisternal penicillin; observations of its effect on dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986642"}
{"pmid": "20986643", "title": "Galactemia.", "content": "Galactemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986643"}
{"pmid": "20986644", "title": "Immunization with tetanus toxoid; the persistence of antitoxin and the effect of stimulating doses of alum-precipitated tetanus toxoid after a five-year period.", "content": "Immunization with tetanus toxoid; the persistence of antitoxin and the effect of stimulating doses of alum-precipitated tetanus toxoid after a five-year period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986644"}
{"pmid": "20986645", "title": "Establishment of a transfusion clinic; treatment of Mediterranean anemia in the outpatient department.", "content": "Establishment of a transfusion clinic; treatment of Mediterranean anemia in the outpatient department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986645"}
{"pmid": "20986646", "title": "Does milk between meals hamper the appetite or food intake of the child?", "content": "Does milk between meals hamper the appetite or food intake of the child?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986646"}
{"pmid": "20986647", "title": "Dye poisoning in infancy.", "content": "Dye poisoning in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986647"}
{"pmid": "20986648", "title": "A case of tetralogy of Fallot with absence of cerebellar vermis; termination by brain abscess.", "content": "A case of tetralogy of Fallot with absence of cerebellar vermis; termination by brain abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986648"}
{"pmid": "20986649", "title": "A practical urine or wet diaper signal.", "content": "A practical urine or wet diaper signal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986649"}
{"pmid": "20986650", "title": "Addison's disease in children.", "content": "Addison's disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986650"}
{"pmid": "20986655", "title": "An investigation of Brazilian sassafras oil; a comparison with oil of sassafras U.S.P. in regard to taste and odor preference.", "content": "An investigation of Brazilian sassafras oil; a comparison with oil of sassafras U.S.P. in regard to taste and odor preference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986655"}
{"pmid": "20986656", "title": "Fifty years of atomic energy.", "content": "Fifty years of atomic energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986656"}
{"pmid": "20986657", "title": "Atomic power and disease.", "content": "Atomic power and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986657"}
{"pmid": "20986673", "title": "Alterations in reproductive functions of white rats associated with daily exposure to nicotine.", "content": "Alterations in reproductive functions of white rats associated with daily exposure to nicotine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986673"}
{"pmid": "20986675", "title": "2,2-bis (p-chlorophenyl)-1,1,1-trichloroethane (DDT) in the tissues of the rat following oral ingestion for periods of six months to two years.", "content": "2,2-bis (p-chlorophenyl)-1,1,1-trichloroethane (DDT) in the tissues of the rat following oral ingestion for periods of six months to two years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986675"}
{"pmid": "20986674", "title": "Toxicology of 1,2-dichloropropane (propylene dichloride); influence of dietary factors on the toxicity of dichloropropane.", "content": "Toxicology of 1,2-dichloropropane (propylene dichloride); influence of dietary factors on the toxicity of dichloropropane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986674"}
{"pmid": "20986676", "title": "On the expectorant action of parasympathomimetic drugs.", "content": "On the expectorant action of parasympathomimetic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986676"}
{"pmid": "20986677", "title": "Pyruvic acid antagonism to barbiturate depression.", "content": "Pyruvic acid antagonism to barbiturate depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986677"}
{"pmid": "20986678", "title": "The effects of senecionine on the monkey.", "content": "The effects of senecionine on the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986678"}
{"pmid": "20986679", "title": "Competitive inhibition of procaine convulsions in guinea pigs.", "content": "Competitive inhibition of procaine convulsions in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986679"}
{"pmid": "20986680", "title": "Studies on the mechanism of action of thiourea and related compounds; metabolic changes after acute poisoning by alphanaphthylthiourea.", "content": "Studies on the mechanism of action of thiourea and related compounds; metabolic changes after acute poisoning by alphanaphthylthiourea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986680"}
{"pmid": "20986681", "title": "The action of 1,1-diphenyl-1 (dimethylaminoisopropyl) butanone-2, a potent analgesic agent.", "content": "The action of 1,1-diphenyl-1 (dimethylaminoisopropyl) butanone-2, a potent analgesic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986681"}
{"pmid": "20986684", "title": "Aerosol toxicity; effect of the nonvolatile content of a DDT aerosol on mortality of houseflies.", "content": "Aerosol toxicity; effect of the nonvolatile content of a DDT aerosol on mortality of houseflies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986684"}
{"pmid": "20986686", "title": "Effects of ultraviolet radiation.", "content": "Effects of ultraviolet radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986686"}
{"pmid": "20986687", "title": "Physiological aspects of genetics.", "content": "Physiological aspects of genetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986687"}
{"pmid": "20986688", "title": "Developmental physiology.", "content": "Developmental physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986688"}
{"pmid": "20986689", "title": "Physiology of heat and cold.", "content": "Physiology of heat and cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986689"}
{"pmid": "20986690", "title": "Energy metabolism.", "content": "Energy metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986690"}
{"pmid": "20986691", "title": "Respiration.", "content": "Respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986691"}
{"pmid": "20986692", "title": "The physiology of the skin.", "content": "The physiology of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986692"}
{"pmid": "20986693", "title": "Digestive system.", "content": "Digestive system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986693"}
{"pmid": "20986694", "title": "Liver and bile.", "content": "Liver and bile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986694"}
{"pmid": "20986695", "title": "Kidney.", "content": "Kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986695"}
{"pmid": "20986696", "title": "Blood coagulation, thrombosis, and hemorrhagic disorders.", "content": "Blood coagulation, thrombosis, and hemorrhagic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986696"}
{"pmid": "20986697", "title": "Blood cytology.", "content": "Blood cytology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986697"}
{"pmid": "20986698", "title": "The lymphatic system.", "content": "The lymphatic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986698"}
{"pmid": "20986699", "title": "Heart.", "content": "Heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986699"}
{"pmid": "20986700", "title": "Shock.", "content": "Shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986700"}
{"pmid": "20986701", "title": "Nerve and synaptic conduction.", "content": "Nerve and synaptic conduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986701"}
{"pmid": "20986703", "title": "The somatic functions of the central nervous system.", "content": "The somatic functions of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986703"}
{"pmid": "20986702", "title": "The visceral functions of the nervous system.", "content": "The visceral functions of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986702"}
{"pmid": "20986704", "title": "Audition.", "content": "Audition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986704"}
{"pmid": "20986705", "title": "Metabolic functions of the endocrine glands.", "content": "Metabolic functions of the endocrine glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986705"}
{"pmid": "20986706", "title": "Reproduction.", "content": "Reproduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986706"}
{"pmid": "20986707", "title": "Aviation physiology.", "content": "Aviation physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986707"}
{"pmid": "20986708", "title": "Physiological psychology.", "content": "Physiological psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986708"}
{"pmid": "20986709", "title": "Applied physiology.", "content": "Applied physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986709"}
{"pmid": "20986710", "title": "Pharmacology.", "content": "Pharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986710"}
{"pmid": "20986711", "title": "Output rates among butter wrappers; work curves and their stability.", "content": "Output rates among butter wrappers; work curves and their stability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986711"}
{"pmid": "20986712", "title": "Management's reactions to employee opinion polls.", "content": "Management's reactions to employee opinion polls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986712"}
{"pmid": "20986713", "title": "Signed versus unsigned personal questionnaires.", "content": "Signed versus unsigned personal questionnaires.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986713"}
{"pmid": "20986714", "title": "Age of college graduation and success in adult life.", "content": "Age of college graduation and success in adult life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986714"}
{"pmid": "20986715", "title": "Predicting success in a school of nursing.", "content": "Predicting success in a school of nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986715"}
{"pmid": "20986716", "title": "Teachers college students and the Minnesota Multiphasic Personality Inventory.", "content": "Teachers college students and the Minnesota Multiphasic Personality Inventory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986716"}
{"pmid": "20986717", "title": "The occupational adjustment characteristics of a group of sexually promiscuous and venereally infected females.", "content": "The occupational adjustment characteristics of a group of sexually promiscuous and venereally infected females.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986717"}
{"pmid": "20986718", "title": "The effect of prolonged mild anoxia on speech intelligibility.", "content": "The effect of prolonged mild anoxia on speech intelligibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986718"}
{"pmid": "20986719", "title": "Studies in International Morse code; the effect of the phonetic equivalent.", "content": "Studies in International Morse code; the effect of the phonetic equivalent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986719"}
{"pmid": "20986720", "title": "Validity of the Hunt-Minnesota Test for Organic Brain Damage.", "content": "Validity of the Hunt-Minnesota Test for Organic Brain Damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986720"}
{"pmid": "20986721", "title": "The Hunt-Minnesota Test for Organic Brain Damage in cases of functional depression.", "content": "The Hunt-Minnesota Test for Organic Brain Damage in cases of functional depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986721"}
{"pmid": "20986722", "title": "A single plane method of rotation.", "content": "A single plane method of rotation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986722"}
{"pmid": "20986723", "title": "The test-retest reliability of qualitative data.", "content": "The test-retest reliability of qualitative data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986723"}
{"pmid": "20986724", "title": "The significance of difference between means without reference to the frequency distribution function.", "content": "The significance of difference between means without reference to the frequency distribution function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986724"}
{"pmid": "20986725", "title": "General solution of the analysis of variance and covariance in the case of unequal or disproportionate numbers of observations in the subclasses.", "content": "General solution of the analysis of variance and covariance in the case of unequal or disproportionate numbers of observations in the subclasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986725"}
{"pmid": "20986726", "title": "A new method for analyzing anesthetic preferences; some theoretical considerations.", "content": "A new method for analyzing anesthetic preferences; some theoretical considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986726"}
{"pmid": "20986727", "title": "Maternal and child welfare care.", "content": "Maternal and child welfare care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986727"}
{"pmid": "20986741", "title": "Treatment of fractures.", "content": "Treatment of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986741"}
{"pmid": "20986743", "title": "State partnership for recreation.", "content": "State partnership for recreation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986743"}
{"pmid": "20986744", "title": "Physical education in peacetime.", "content": "Physical education in peacetime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986744"}
{"pmid": "20986745", "title": "Continental treatment of tuberculosis.", "content": "Continental treatment of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986745"}
{"pmid": "20986746", "title": "Penicillin in diphtheria.", "content": "Penicillin in diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986746"}
{"pmid": "20986747", "title": "SOCIAL survey inquiry on diphtheria immunisation.", "content": "SOCIAL survey inquiry on diphtheria immunisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986747"}
{"pmid": "20986748", "title": "Sanitary engineering and public health.", "content": "Sanitary engineering and public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986748"}
{"pmid": "20986749", "title": "Nursing education at Indiana University 1931-1945.", "content": "Nursing education at Indiana University 1931-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986749"}
{"pmid": "20986754", "title": "UNRRA's health work in Europe.", "content": "UNRRA's health work in Europe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986754"}
{"pmid": "20986756", "title": "A new concept of coagulation.", "content": "A new concept of coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986756"}
{"pmid": "20986755", "title": "Screen clogging by a rare species of algae.", "content": "Screen clogging by a rare species of algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986755"}
{"pmid": "20986757", "title": "Sludge index control by chlorination.", "content": "Sludge index control by chlorination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986757"}
{"pmid": "20986758", "title": "Odor control and control of filter flies; a review of current practices.", "content": "Odor control and control of filter flies; a review of current practices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986758"}
{"pmid": "20986759", "title": "Repair of surface defects of the upper extremity.", "content": "Repair of surface defects of the upper extremity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986759"}
{"pmid": "20986760", "title": "Experiences with early nerve surgery in peripheral nerve injuries.", "content": "Experiences with early nerve surgery in peripheral nerve injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986760"}
{"pmid": "20986761", "title": "Mediastinal tumors; report of cases treated at Army thoracic surgery centers in the United States.", "content": "Mediastinal tumors; report of cases treated at Army thoracic surgery centers in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986761"}
{"pmid": "20986762", "title": "Angiomatous malformations of the brain; successful extirpation in three cases.", "content": "Angiomatous malformations of the brain; successful extirpation in three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986762"}
{"pmid": "20986753", "title": "Characteristics of water bacteria.", "content": "Characteristics of water bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986753"}
{"pmid": "20986763", "title": "An analysis of brain abscesses observed during the past thirty years.", "content": "An analysis of brain abscesses observed during the past thirty years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986763"}
{"pmid": "20986764", "title": "Craniotomy and total dissection as a method in the treatment of the brain.", "content": "Craniotomy and total dissection as a method in the treatment of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986764"}
{"pmid": "20986765", "title": "Streptomycin in urinary infections.", "content": "Streptomycin in urinary infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986765"}
{"pmid": "20986766", "title": "A new method for constructing an artificial esophagus.", "content": "A new method for constructing an artificial esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986766"}
{"pmid": "20986767", "title": "Experiences in subtotal resection of the pancreas in hypoglycemia.", "content": "Experiences in subtotal resection of the pancreas in hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986767"}
{"pmid": "20986768", "title": "Indications for and value of choledochoduodenostomy.", "content": "Indications for and value of choledochoduodenostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986768"}
{"pmid": "20986769", "title": "Malignant tumors of the small bowel.", "content": "Malignant tumors of the small bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986769"}
{"pmid": "20986770", "title": "Restoration of continuity after resection of the rectum.", "content": "Restoration of continuity after resection of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986770"}
{"pmid": "20986771", "title": "Further observations upon imperforate anus.", "content": "Further observations upon imperforate anus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986771"}
{"pmid": "20986772", "title": "Congenital defect of the abdominal wall in the new born (gastroschisis).", "content": "Congenital defect of the abdominal wall in the new born (gastroschisis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986772"}
{"pmid": "20986773", "title": "Gangrenous suppurative appendicitis; forty-eight consecutive cases with removal of the appendix and complete closure of the wound, without a death.", "content": "Gangrenous suppurative appendicitis; forty-eight consecutive cases with removal of the appendix and complete closure of the wound, without a death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986773"}
{"pmid": "20986774", "title": "An investigation of the role of chemotherapy in wound management in the Mediterranean Theater.", "content": "An investigation of the role of chemotherapy in wound management in the Mediterranean Theater.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986774"}
{"pmid": "20986775", "title": "The prevention and treatment of postoperative lymphedema of the arm.", "content": "The prevention and treatment of postoperative lymphedema of the arm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986775"}
{"pmid": "20986776", "title": "Refrigeration anesthesia for amputation.", "content": "Refrigeration anesthesia for amputation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986776"}
{"pmid": "20986777", "title": "Vertical traction; an aid in the surgical management of certain large tumors; case report.", "content": "Vertical traction; an aid in the surgical management of certain large tumors; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986777"}
{"pmid": "20986778", "title": "The treatment of sebaceous cyst by electrosurgical marsupialization.", "content": "The treatment of sebaceous cyst by electrosurgical marsupialization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986778"}
{"pmid": "20986779", "title": "Sideswipe fractures.", "content": "Sideswipe fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986779"}
{"pmid": "20986781", "title": "Acute gastroduodenal obstruction (dilatation).", "content": "Acute gastroduodenal obstruction (dilatation).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986781"}
{"pmid": "20986780", "title": "Anaphylaxis-like reactions produced by ascaris extracts; the changes in the histamine content and the coagulability of the blood in guinea pigs and in dogs.", "content": "Anaphylaxis-like reactions produced by ascaris extracts; the changes in the histamine content and the coagulability of the blood in guinea pigs and in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986780"}
{"pmid": "20986782", "title": "Repair of ruptures through the larger tendons by removable staple suture; a preliminary report.", "content": "Repair of ruptures through the larger tendons by removable staple suture; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986782"}
{"pmid": "20986783", "title": "Plan for the care of peripheral nerve injuries overseas.", "content": "Plan for the care of peripheral nerve injuries overseas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986783"}
{"pmid": "20986784", "title": "Morphology and variations of the duodenal vasculature; relationship to the problems of leakage from a postgastrectomy duodenal stump, bleeding peptic ulcer and injury to the common duct.", "content": "Morphology and variations of the duodenal vasculature; relationship to the problems of leakage from a postgastrectomy duodenal stump, bleeding peptic ulcer and injury to the common duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986784"}
{"pmid": "20986785", "title": "Total gastrectomy; report of six cases.", "content": "Total gastrectomy; report of six cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986785"}
{"pmid": "20986786", "title": "Nonadherent surgical dressings.", "content": "Nonadherent surgical dressings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986786"}
{"pmid": "20986787", "title": "Surgical problems in the later stages of penetrating head injuries.", "content": "Surgical problems in the later stages of penetrating head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986787"}
{"pmid": "20986789", "title": "The place of surgery in the treatment of pulmonary tuberculosis.", "content": "The place of surgery in the treatment of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986789"}
{"pmid": "20986788", "title": "Ectopia vesicae.", "content": "Ectopia vesicae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986788"}
{"pmid": "20986790", "title": "A comparison of the tensile strengths of iodine sterilized and heat sterilized catgut sutures.", "content": "A comparison of the tensile strengths of iodine sterilized and heat sterilized catgut sutures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986790"}
{"pmid": "20986791", "title": "An osteotomy to correct right-angle deformity.", "content": "An osteotomy to correct right-angle deformity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986791"}
{"pmid": "20986792", "title": "Parathyroid tumour; report of a case and surgical discussion.", "content": "Parathyroid tumour; report of a case and surgical discussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986792"}
{"pmid": "20986793", "title": "Extensive airscrew injuries of the skull and brain with recovery of the patient.", "content": "Extensive airscrew injuries of the skull and brain with recovery of the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986793"}
{"pmid": "20986842", "title": "Effect of atropine sulfate and syntropan upon local anesthesia of the eye produced by procaine hydrochloride*: a statistical analysis of the data.", "content": "Effect of atropine sulfate and syntropan upon local anesthesia of the eye produced by procaine hydrochloride*: a statistical analysis of the data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986842"}
{"pmid": "20986845", "title": "Intravenous anesthesia in war surgery.", "content": "Intravenous anesthesia in war surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986845"}
{"pmid": "20986844", "title": "The local anesthetic action of (beta)-phenylazo (alpha)-(alpha)' diamino pyridine monohydrochloride (pyridium) and its metabolites.*", "content": "The local anesthetic action of (beta)-phenylazo (alpha)-(alpha)' diamino pyridine monohydrochloride (pyridium) and its metabolites.*", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986844"}
{"pmid": "20986847", "title": "The compact anesthetic box.", "content": "The compact anesthetic box.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986847"}
{"pmid": "20986843", "title": "Anesthesia in thoracic surgery.", "content": "Anesthesia in thoracic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986843"}
{"pmid": "20986846", "title": "The importance of autopsy in deaths on the operating table.", "content": "The importance of autopsy in deaths on the operating table.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986846"}
{"pmid": "20986850", "title": "Resuscitation.", "content": "Resuscitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986850"}
{"pmid": "20986849", "title": "Anesthetic for minor cases.", "content": "Anesthetic for minor cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986849"}
{"pmid": "20986848", "title": "The so-called Mayo tube.", "content": "The so-called Mayo tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986848"}
{"pmid": "20986851", "title": "Some surgical emergencies.", "content": "Some surgical emergencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986851"}
{"pmid": "20986852", "title": "Advances in the operative treatment of cancer of the large bowel.", "content": "Advances in the operative treatment of cancer of the large bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986852"}
{"pmid": "20986855", "title": "Contributions to the study of extramedullary plasmocytoma.", "content": "Contributions to the study of extramedullary plasmocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986855"}
{"pmid": "20986853", "title": "Surgery of the stomach and duodenum at a naval hospital.", "content": "Surgery of the stomach and duodenum at a naval hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986853"}
{"pmid": "20986854", "title": "Plastic reconstruction of the breast and free transplantation of the nipple.", "content": "Plastic reconstruction of the breast and free transplantation of the nipple.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986854"}
{"pmid": "20986859", "title": "Cancer of the larynx; radiotherapeutic and surgical considerations.", "content": "Cancer of the larynx; radiotherapeutic and surgical considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986859"}
{"pmid": "20986856", "title": "Craniocerebral injuries and the general surgeon.", "content": "Craniocerebral injuries and the general surgeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986856"}
{"pmid": "20986863", "title": "Tumors of the male breast.", "content": "Tumors of the male breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986863"}
{"pmid": "20986857", "title": "Perianal suppuration.", "content": "Perianal suppuration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986857"}
{"pmid": "20986858", "title": "Rebuilding bony depressions of the face and skull.", "content": "Rebuilding bony depressions of the face and skull.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986858"}
{"pmid": "20986860", "title": "Exstrophy of the ileum through a patent omphalomesenteric duct with strangulated umbilical hernia; case report.", "content": "Exstrophy of the ileum through a patent omphalomesenteric duct with strangulated umbilical hernia; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986860"}
{"pmid": "20986861", "title": "Ecchymotic mask.", "content": "Ecchymotic mask.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986861"}
{"pmid": "20986862", "title": "Treatment and prevention of thrombosis with dicoumarol.", "content": "Treatment and prevention of thrombosis with dicoumarol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986862"}
{"pmid": "20986899", "title": "Initial surgery of compound fractures and concurrent muscle, nerve and blood vessel injuries in an evacuation hospital.", "content": "Initial surgery of compound fractures and concurrent muscle, nerve and blood vessel injuries in an evacuation hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986899"}
{"pmid": "20986905", "title": "Ureterocele.", "content": "Ureterocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986905"}
{"pmid": "20986913", "title": "Peripheral nerve injuries; the results of early nerve suture; a preliminary report.", "content": "Peripheral nerve injuries; the results of early nerve suture; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986913"}
{"pmid": "20986914", "title": "Decompression of the orbit.", "content": "Decompression of the orbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986914"}
{"pmid": "20986915", "title": "A method of encephalography.", "content": "A method of encephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986915"}
{"pmid": "20986916", "title": "A study of the azotemia observed after severe burns.", "content": "A study of the azotemia observed after severe burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986916"}
{"pmid": "20986917", "title": "Surgery of colon as seen in an overseas general hospital.", "content": "Surgery of colon as seen in an overseas general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986917"}
{"pmid": "20986918", "title": "Organization and operation of a vascular center.", "content": "Organization and operation of a vascular center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986918"}
{"pmid": "20986919", "title": "New method for testing collateral circulation.", "content": "New method for testing collateral circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986919"}
{"pmid": "20986920", "title": "Basal vascular tone as an indication for sympathectomy.", "content": "Basal vascular tone as an indication for sympathectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986920"}
{"pmid": "20986921", "title": "Treatment of arteriovenous aneurysm.", "content": "Treatment of arteriovenous aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986921"}
{"pmid": "20986922", "title": "Ambulation of paraplegic patients.", "content": "Ambulation of paraplegic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986922"}
{"pmid": "20986923", "title": "Surgical treatment of empyema.", "content": "Surgical treatment of empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986923"}
{"pmid": "20986924", "title": "Reconstructive surgery of the hand.", "content": "Reconstructive surgery of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986924"}
{"pmid": "20986925", "title": "Treatment of severe elbow injuries.", "content": "Treatment of severe elbow injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986925"}
{"pmid": "20986926", "title": "Surgical treatment and prognosis of protruded intervertebral disc.", "content": "Surgical treatment and prognosis of protruded intervertebral disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986926"}
{"pmid": "20986927", "title": "Peripheral nerve repair.", "content": "Peripheral nerve repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986927"}
{"pmid": "20986928", "title": "Roentgen findings in peptic ulcer.", "content": "Roentgen findings in peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986928"}
{"pmid": "20986929", "title": "Surgical significance of hepatitis.", "content": "Surgical significance of hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986929"}
{"pmid": "20986930", "title": "Blood distase and acute abdominal pain.", "content": "Blood distase and acute abdominal pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986930"}
{"pmid": "20986931", "title": "Repair of primary and recurrent hernia.", "content": "Repair of primary and recurrent hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986931"}
{"pmid": "20986932", "title": "Laboratory adjuncts in transfusion.", "content": "Laboratory adjuncts in transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986932"}
{"pmid": "20986933", "title": "Cancer of the breast; statistical report of results.", "content": "Cancer of the breast; statistical report of results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986933"}
{"pmid": "20986934", "title": "Treatment of acute war wounds of the abdomen.", "content": "Treatment of acute war wounds of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986934"}
{"pmid": "20986935", "title": "Brief report of three large surgical cases.", "content": "Brief report of three large surgical cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986935"}
{"pmid": "20986936", "title": "Hallux valgus reoperations.", "content": "Hallux valgus reoperations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986936"}
{"pmid": "20986937", "title": "An unusually large tubal pregnancy.", "content": "An unusually large tubal pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986937"}
{"pmid": "20986938", "title": "Medical and social customs among the native inhabitants of Guadalcanal.", "content": "Medical and social customs among the native inhabitants of Guadalcanal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986938"}
{"pmid": "20986939", "title": "ROENTGEN therapy of benign giant cell tumor of bone.", "content": "ROENTGEN therapy of benign giant cell tumor of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986939"}
{"pmid": "20986940", "title": "The art of crutch walking.", "content": "The art of crutch walking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986940"}
{"pmid": "20986941", "title": "Educational services in a naval hospital.", "content": "Educational services in a naval hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986941"}
{"pmid": "20986942", "title": "A page-turning device for respirator patients.", "content": "A page-turning device for respirator patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986942"}
{"pmid": "20986953", "title": "Abdominal aortic aneurysm simulating perinephritic abscess; dorsolumbar scoliosis a roentgen sign of aneurysm.", "content": "Abdominal aortic aneurysm simulating perinephritic abscess; dorsolumbar scoliosis a roentgen sign of aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986953"}
{"pmid": "20986954", "title": "Urologic surgery in tuberculous patients.", "content": "Urologic surgery in tuberculous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986954"}
{"pmid": "20986955", "title": "Surgical accidents of the urinary tract.", "content": "Surgical accidents of the urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986955"}
{"pmid": "20986957", "title": "Transfusion syphilis with an analysis of the immunologic reactions.", "content": "Transfusion syphilis with an analysis of the immunologic reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986957"}
{"pmid": "20986956", "title": "Pelvic single kidney; report case.", "content": "Pelvic single kidney; report case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986956"}
{"pmid": "20986958", "title": "A contribution to the diagnosis and treatment of pemphigus.", "content": "A contribution to the diagnosis and treatment of pemphigus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986958"}
{"pmid": "20986959", "title": "The sedimentation rate in the eczema of infants and children.", "content": "The sedimentation rate in the eczema of infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986959"}
{"pmid": "20986960", "title": "The effect of tetra-chloro-para-benzoquinone upon human fungus infections; in vitro and in vivo studies with tinea capitis.", "content": "The effect of tetra-chloro-para-benzoquinone upon human fungus infections; in vitro and in vivo studies with tinea capitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986960"}
{"pmid": "20986961", "title": "Acroerythrosis with associated analogous palmar changes in pulmonary tuberculosis.", "content": "Acroerythrosis with associated analogous palmar changes in pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986961"}
{"pmid": "20986962", "title": "Herpes gestationis; report of a case occurring post-partum on three separate occasions.", "content": "Herpes gestationis; report of a case occurring post-partum on three separate occasions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986962"}
{"pmid": "20986963", "title": "Highlights of the Conference in Tropical Dermatology for American Doctors at Mexico City, August 6-18, 1945.", "content": "Highlights of the Conference in Tropical Dermatology for American Doctors at Mexico City, August 6-18, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986963"}
{"pmid": "20986964", "title": "[CALCULOUS bodies of the urinary bladder].", "content": "[CALCULOUS bodies of the urinary bladder].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986964"}
{"pmid": "20986965", "title": "NATIONAL venereal disease control.", "content": "NATIONAL venereal disease control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986965"}
{"pmid": "20986966", "title": "Sensitivity of Neisseria gonorrhoeae to streptomycin in vitro.", "content": "Sensitivity of Neisseria gonorrhoeae to streptomycin in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986966"}
{"pmid": "20986967", "title": "Treatment of gonorrhea with penicillin.", "content": "Treatment of gonorrhea with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986967"}
{"pmid": "20986968", "title": "An unusual strain of Neisseria isolated from the cervix uteri.", "content": "An unusual strain of Neisseria isolated from the cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986968"}
{"pmid": "20986987", "title": "The histochemistry of the rodent's placenta.", "content": "The histochemistry of the rodent's placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986987"}
{"pmid": "20986988", "title": "Some evidences of specific secretory activity of the anterior pituitary gland of the cat.", "content": "Some evidences of specific secretory activity of the anterior pituitary gland of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986988"}
{"pmid": "20986989", "title": "Sexual rhythms in the reproductive tract of the adult female opossum and effects of hormonal treatments.", "content": "Sexual rhythms in the reproductive tract of the adult female opossum and effects of hormonal treatments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986989"}
{"pmid": "20986990", "title": "Anomalies in the small intestine and cecum of inbred strains of mice.", "content": "Anomalies in the small intestine and cecum of inbred strains of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986990"}
{"pmid": "20986991", "title": "The innervation of the first dorsal interosseous muscle of the hand.", "content": "The innervation of the first dorsal interosseous muscle of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986991"}
{"pmid": "20986985", "title": "Arteriovenous anastomoses in the endometrium in man.", "content": "Arteriovenous anastomoses in the endometrium in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986985"}
{"pmid": "20986993", "title": "The postpartum history of the corpus luteum of the cat.", "content": "The postpartum history of the corpus luteum of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986993"}
{"pmid": "20986992", "title": "A cytological study of the anterior hypophysis of the dog with particular reference to the presence of a fourth cell type.", "content": "A cytological study of the anterior hypophysis of the dog with particular reference to the presence of a fourth cell type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986992"}
{"pmid": "20986994", "title": "An arterial anomaly in the fetal pig.", "content": "An arterial anomaly in the fetal pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986994"}
{"pmid": "20986995", "title": "A case of atypical twinning in Fundulus heteroclitus.", "content": "A case of atypical twinning in Fundulus heteroclitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986995"}
{"pmid": "20986996", "title": "Effect of radar emmanations on the hematopoietic system.", "content": "Effect of radar emmanations on the hematopoietic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986996"}
{"pmid": "20986997", "title": "Practice of medicine during the Japanese occupation of the Philippine Islands.", "content": "Practice of medicine during the Japanese occupation of the Philippine Islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986997"}
{"pmid": "20986999", "title": "The flight surgeon and commercial aviation.", "content": "The flight surgeon and commercial aviation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986999"}
{"pmid": "20986998", "title": "Is CO oxidized to CO2 in the human body.", "content": "Is CO oxidized to CO2 in the human body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20986998"}
{"pmid": "20987000", "title": "Safety advantage of rearward seating in passenger aircraft.", "content": "Safety advantage of rearward seating in passenger aircraft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987000"}
{"pmid": "20987001", "title": "Tests on clothing impregnated with DDT as an anti-louse measure.", "content": "Tests on clothing impregnated with DDT as an anti-louse measure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987001"}
{"pmid": "20987002", "title": "The use of DDT as a mosquito larvicide; flowing water.", "content": "The use of DDT as a mosquito larvicide; flowing water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987002"}
{"pmid": "20987004", "title": "A new method of trapping flies.", "content": "A new method of trapping flies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987004"}
{"pmid": "20987003", "title": "Mercury as a preventive against stored grain pests.", "content": "Mercury as a preventive against stored grain pests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987003"}
{"pmid": "20987005", "title": "The development of quick microtechniques for the identification of cultures.", "content": "The development of quick microtechniques for the identification of cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987005"}
{"pmid": "20987006", "title": "Applicability of modifications of the thin filter paper disc method to the assay of enzymes.", "content": "Applicability of modifications of the thin filter paper disc method to the assay of enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987006"}
{"pmid": "20987007", "title": "A critical evaluation of the nitrogen assimilation tests as commonly used in the classification of the yeasts.", "content": "A critical evaluation of the nitrogen assimilation tests as commonly used in the classification of the yeasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987007"}
{"pmid": "20987008", "title": "Production of vitamin B2 by Mycobacterium smegmatis.", "content": "Production of vitamin B2 by Mycobacterium smegmatis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987008"}
{"pmid": "20987009", "title": "Recovery of biotin from cultures of acetone, butyl alcohol bacteria.", "content": "Recovery of biotin from cultures of acetone, butyl alcohol bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987009"}
{"pmid": "20987010", "title": "The amino acid composition of microorganisms.", "content": "The amino acid composition of microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987010"}
{"pmid": "20987011", "title": "The amino acid composition of crystalline botulinus (type A) toxin.", "content": "The amino acid composition of crystalline botulinus (type A) toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987011"}
{"pmid": "20987012", "title": "The nutrition of Coccidioides immitis in submerged culture.", "content": "The nutrition of Coccidioides immitis in submerged culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987012"}
{"pmid": "20987013", "title": "Plating media requirements for certain strains of Bacterium tularense.", "content": "Plating media requirements for certain strains of Bacterium tularense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987013"}
{"pmid": "20987014", "title": "The oxidation of glycerol by Escherichia freundii.", "content": "The oxidation of glycerol by Escherichia freundii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987014"}
{"pmid": "20987015", "title": "Significance in nutritional research of correct identification of Lactobacillus casei, L. delbrueckii, and L. bulgaricus.", "content": "Significance in nutritional research of correct identification of Lactobacillus casei, L. delbrueckii, and L. bulgaricus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987015"}
{"pmid": "20987016", "title": "Fixation of heavy carbon acetaldehyde by active juices.", "content": "Fixation of heavy carbon acetaldehyde by active juices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987016"}
{"pmid": "20987017", "title": "Factors influencing the anaerobic production of gas by Bacillus subtilis.", "content": "Factors influencing the anaerobic production of gas by Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987017"}
{"pmid": "20987018", "title": "Relationships of Proshigella dispar to other Proshigella and Shigella species.", "content": "Relationships of Proshigella dispar to other Proshigella and Shigella species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987018"}
{"pmid": "20987019", "title": "Studies on myxobacteria.", "content": "Studies on myxobacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987019"}
{"pmid": "20987020", "title": "Induced resistance of Staphylococcus aureus to antibiotics.", "content": "Induced resistance of Staphylococcus aureus to antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987020"}
{"pmid": "20987021", "title": "Development of streptomycin resistance of the shigellae.", "content": "Development of streptomycin resistance of the shigellae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987021"}
{"pmid": "20987022", "title": "Immunologic aspects of protein metabolism.", "content": "Immunologic aspects of protein metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987022"}
{"pmid": "20987023", "title": "The structure of Spirochaeta novyi as revealed by the electron microscope.", "content": "The structure of Spirochaeta novyi as revealed by the electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987023"}
{"pmid": "20987024", "title": "A comparison of electron micrographs with photomicrographs of young bacterial cultures stained to demonstrate desoxyribosenucleic acid.", "content": "A comparison of electron micrographs with photomicrographs of young bacterial cultures stained to demonstrate desoxyribosenucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987024"}
{"pmid": "20987025", "title": "Reproductive processes in Proteus cultures.", "content": "Reproductive processes in Proteus cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987025"}
{"pmid": "20987026", "title": "Nuclear staining of Escherichia coli.", "content": "Nuclear staining of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987026"}
{"pmid": "20987027", "title": "The viability of dried Lactobacillus bulgaricus cultures as affected by the temperature of the reconstituting fluid.", "content": "The viability of dried Lactobacillus bulgaricus cultures as affected by the temperature of the reconstituting fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987027"}
{"pmid": "20987028", "title": "Isolation of enterococci from natural sources.", "content": "Isolation of enterococci from natural sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987028"}
{"pmid": "20987029", "title": "The cellulose-decomposing bacteria in the rumen of cattle.", "content": "The cellulose-decomposing bacteria in the rumen of cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987029"}
{"pmid": "20987030", "title": "The effects of quality and pasteurization of milk on the bacterial flora and quality of chedder cheese.", "content": "The effects of quality and pasteurization of milk on the bacterial flora and quality of chedder cheese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987030"}
{"pmid": "20987031", "title": "Eumycin, a new antibiotic active against pathogenic fungi and higher bacteria, including bacilli of tuberculosis and diphtheria.", "content": "Eumycin, a new antibiotic active against pathogenic fungi and higher bacteria, including bacilli of tuberculosis and diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987031"}
{"pmid": "20987032", "title": "The effect of subtilin in the treatment of experimental infections in animals.", "content": "The effect of subtilin in the treatment of experimental infections in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987032"}
{"pmid": "20987033", "title": "The inhibitory action of saliva on the diphtheria bacillus; the antibiotic effect of salivary streptococci.", "content": "The inhibitory action of saliva on the diphtheria bacillus; the antibiotic effect of salivary streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987033"}
{"pmid": "20987034", "title": "Changes in the bacterial flora of the throat and intestinal tract during prolonged oral administration of penicillin.", "content": "Changes in the bacterial flora of the throat and intestinal tract during prolonged oral administration of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987034"}
{"pmid": "20987035", "title": "The production of fungal amylases in submerged culture and their use in the production of industrial alcohol.", "content": "The production of fungal amylases in submerged culture and their use in the production of industrial alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987035"}
{"pmid": "20987036", "title": "Bacteriophage in the 2,3-butylene glycol fermentation.", "content": "Bacteriophage in the 2,3-butylene glycol fermentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987036"}
{"pmid": "20987037", "title": "The use of corn steeping liquor in microbiological research.", "content": "The use of corn steeping liquor in microbiological research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987037"}
{"pmid": "20987038", "title": "The effect of beta radiation on the production of penicillin.", "content": "The effect of beta radiation on the production of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987038"}
{"pmid": "20987039", "title": "Studies on a spirochete found in the blood of sick turkeys.", "content": "Studies on a spirochete found in the blood of sick turkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987039"}
{"pmid": "20987040", "title": "Fermentation of organic acids by marine mud cultures.", "content": "Fermentation of organic acids by marine mud cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987040"}
{"pmid": "20987041", "title": "Effect of growth of microorganisms upon formation of peroxides free fatty acids, aldehydes, and ketones from oils with different iodine numbers.", "content": "Effect of growth of microorganisms upon formation of peroxides free fatty acids, aldehydes, and ketones from oils with different iodine numbers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987041"}
{"pmid": "20987042", "title": "The effect of agar upon the germicidal potency of the quaternary ammonium salts.", "content": "The effect of agar upon the germicidal potency of the quaternary ammonium salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987042"}
{"pmid": "20987043", "title": "The evaluation of germicidal agents by an infection-prevention toxicity method.", "content": "The evaluation of germicidal agents by an infection-prevention toxicity method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987043"}
{"pmid": "20987044", "title": "In vitro studies on the synergic action of sulfonamides and certain substituted diphenylalkyl compounds; a preliminary report.", "content": "In vitro studies on the synergic action of sulfonamides and certain substituted diphenylalkyl compounds; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987044"}
{"pmid": "20987045", "title": "The effects of pus on sulfonamide activity.", "content": "The effects of pus on sulfonamide activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987045"}
{"pmid": "20987046", "title": "Factors influencing the action of streptomycin in vitro.", "content": "Factors influencing the action of streptomycin in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987046"}
{"pmid": "20987047", "title": "Studies on streptomycin therapy of experimental tularemia in white mice.", "content": "Studies on streptomycin therapy of experimental tularemia in white mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987047"}
{"pmid": "20987048", "title": "The sensitivity of tubercle bacilli in vitro to streptomycin.", "content": "The sensitivity of tubercle bacilli in vitro to streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987048"}
{"pmid": "20987049", "title": "Aerobacter cloacae as a possible factor in the etiology of bagassosis.", "content": "Aerobacter cloacae as a possible factor in the etiology of bagassosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987049"}
{"pmid": "20987050", "title": "Polyvalent antigens for the serodiagnosis of Salmonella infections.", "content": "Polyvalent antigens for the serodiagnosis of Salmonella infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987050"}
{"pmid": "20987051", "title": "The occurrence of paracolon organisms with Salmonella XXXVIII antigen.", "content": "The occurrence of paracolon organisms with Salmonella XXXVIII antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987051"}
{"pmid": "20987052", "title": "Effect of penicillin aerosol on pneumococcus pneumonia in rats.", "content": "Effect of penicillin aerosol on pneumococcus pneumonia in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987052"}
{"pmid": "20987053", "title": "Specific complement-fixing diagnostic antigens for neurotropic virus diseases.", "content": "Specific complement-fixing diagnostic antigens for neurotropic virus diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987053"}
{"pmid": "20987054", "title": "The neutralization of the mouse-adapted poliomyelitis virus by the sera of children.", "content": "The neutralization of the mouse-adapted poliomyelitis virus by the sera of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987054"}
{"pmid": "20987055", "title": "Studies on equine encephalomyelitis in Michigan.", "content": "Studies on equine encephalomyelitis in Michigan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987055"}
{"pmid": "20987056", "title": "Isolation of a new virus from two fatal pneumonia cases.", "content": "Isolation of a new virus from two fatal pneumonia cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987056"}
{"pmid": "20987057", "title": "Studies on antigenic relationships within the psittacosis-lymphogranuloma group of viruses.", "content": "Studies on antigenic relationships within the psittacosis-lymphogranuloma group of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987057"}
{"pmid": "20987058", "title": "Intraocular infection with the viruses of ornithosis and feline enteritis.", "content": "Intraocular infection with the viruses of ornithosis and feline enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987058"}
{"pmid": "20987059", "title": "Therapeutic use of specific typhoid bacteriophage.", "content": "Therapeutic use of specific typhoid bacteriophage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987059"}
{"pmid": "20987061", "title": "Chemical detoxification of dysentery antigen.", "content": "Chemical detoxification of dysentery antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987061"}
{"pmid": "20987060", "title": "The effect of booster vaccination on protective humoral antibodies against dysentery in children.", "content": "The effect of booster vaccination on protective humoral antibodies against dysentery in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987060"}
{"pmid": "20987062", "title": "Production of potent inactivated vaccines with ultraviolet irradiation; active and passive immunization with lymphocytic choriomeningitis vaccine.", "content": "Production of potent inactivated vaccines with ultraviolet irradiation; active and passive immunization with lymphocytic choriomeningitis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987062"}
{"pmid": "20987063", "title": "The immunization of white rats against tularemia.", "content": "The immunization of white rats against tularemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987063"}
{"pmid": "20987064", "title": "An immunological study involving carcinogenic hydrocarbons.", "content": "An immunological study involving carcinogenic hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987064"}
{"pmid": "20987065", "title": "Studies on biologically universal serum reactions (nonsyphilitic) with lipid antigens.", "content": "Studies on biologically universal serum reactions (nonsyphilitic) with lipid antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987065"}
{"pmid": "20987066", "title": "The reaction of paramecia in specific antiserum.", "content": "The reaction of paramecia in specific antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987066"}
{"pmid": "20987067", "title": "Methods for the irradiation of biological liquids with wavelength 2537 A.", "content": "Methods for the irradiation of biological liquids with wavelength 2537 A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987067"}
{"pmid": "20987068", "title": "Cultural and serological studies on granuloma inguinale.", "content": "Cultural and serological studies on granuloma inguinale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987068"}
{"pmid": "20987069", "title": "Use of the chick embryo for the enhancement of virulence of Hamophilus pertussis.", "content": "Use of the chick embryo for the enhancement of virulence of Hamophilus pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987069"}
{"pmid": "20987070", "title": "Enlivening and clarifying the instruction in bacteriology by the use of audio-visual aids.", "content": "Enlivening and clarifying the instruction in bacteriology by the use of audio-visual aids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987070"}
{"pmid": "20987071", "title": "Reactivation of overneutralized influenza virus.", "content": "Reactivation of overneutralized influenza virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987071"}
{"pmid": "20987072", "title": "Studies on the toxicity of influenza viruses.", "content": "Studies on the toxicity of influenza viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987072"}
{"pmid": "20987073", "title": "Present specifications for commercial streptomycin.", "content": "Present specifications for commercial streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987073"}
{"pmid": "20987074", "title": "The inactivation of streptomycin and its practical applications.", "content": "The inactivation of streptomycin and its practical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987074"}
{"pmid": "20987075", "title": "Present knowledge of the chemotherapeutic properties of streptomycin.", "content": "Present knowledge of the chemotherapeutic properties of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987075"}
{"pmid": "20987076", "title": "The origin of the name Parvobacteriaceae.", "content": "The origin of the name Parvobacteriaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987076"}
{"pmid": "20987077", "title": "The genus Proteus.", "content": "The genus Proteus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987077"}
{"pmid": "20987078", "title": "Taxonomy and the genus Salmonella.", "content": "Taxonomy and the genus Salmonella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987078"}
{"pmid": "20987079", "title": "Bacteriology of frozen foods.", "content": "Bacteriology of frozen foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987079"}
{"pmid": "20987080", "title": "Disinfection of the air by oiling floors and bed clothing.", "content": "Disinfection of the air by oiling floors and bed clothing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987080"}
{"pmid": "20987082", "title": "Immunochemical studies on the Shigella paradysenteriae (Flexner).", "content": "Immunochemical studies on the Shigella paradysenteriae (Flexner).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987082"}
{"pmid": "20987081", "title": "Serological properties of dextrans formed from sucrose by certain streptococci from subacute bacterial endocarditis.", "content": "Serological properties of dextrans formed from sucrose by certain streptococci from subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987081"}
{"pmid": "20987083", "title": "The cellular transfer of cutaneous hypersensitivity.", "content": "The cellular transfer of cutaneous hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987083"}
{"pmid": "20987092", "title": "The possible association between porphyrins and cancer in mice.", "content": "The possible association between porphyrins and cancer in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987092"}
{"pmid": "20987093", "title": "The effects of suramin (germanin), azo dyes, and vasodilators on mice with transplanted lymphosarcomas.", "content": "The effects of suramin (germanin), azo dyes, and vasodilators on mice with transplanted lymphosarcomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987093"}
{"pmid": "20987094", "title": "Induction of mammary cancer with methylcholanthrene; histogenesis of the induced neoplasm.", "content": "Induction of mammary cancer with methylcholanthrene; histogenesis of the induced neoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987094"}
{"pmid": "20987095", "title": "Toxin therapy of experimental cancer; the influence of protozoan infections upon transplanted cancer.", "content": "Toxin therapy of experimental cancer; the influence of protozoan infections upon transplanted cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987095"}
{"pmid": "20987096", "title": "The carcinogenicity of wood soot from the chimney of a smoked sausage factory.", "content": "The carcinogenicity of wood soot from the chimney of a smoked sausage factory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987096"}
{"pmid": "20987097", "title": "Influence of crown-gall bacterial products, crown-gall tissue extracts, and yeast extract on growth in vitro of excised tobacco and sunflower tissue.", "content": "Influence of crown-gall bacterial products, crown-gall tissue extracts, and yeast extract on growth in vitro of excised tobacco and sunflower tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987097"}
{"pmid": "20987101", "title": "Some aspects on the method of calibrated phonocardiography.", "content": "Some aspects on the method of calibrated phonocardiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987101"}
{"pmid": "20987107", "title": "A technique for preparation of palateless full upper dentures.", "content": "A technique for preparation of palateless full upper dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987107"}
{"pmid": "20987108", "title": "Rehabilitation.", "content": "Rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987108"}
{"pmid": "20987109", "title": "Rehabilitation.", "content": "Rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987109"}
{"pmid": "20987136", "title": "Ulcer of the lip following local anaesthesia.", "content": "Ulcer of the lip following local anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987136"}
{"pmid": "20987137", "title": "The loose ends of the caries theories.", "content": "The loose ends of the caries theories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987137"}
{"pmid": "20987138", "title": "Dentistry's contribution to human welfare.", "content": "Dentistry's contribution to human welfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987138"}
{"pmid": "20987139", "title": "Cautaneous cancer from the standpoint of the dermatologist.", "content": "Cautaneous cancer from the standpoint of the dermatologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987139"}
{"pmid": "20987140", "title": "Early diagnosis of cancer of the skin.", "content": "Early diagnosis of cancer of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987140"}
{"pmid": "20987141", "title": "Cutaneous cancer from the surgeon's point of view.", "content": "Cutaneous cancer from the surgeon's point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987141"}
{"pmid": "20987142", "title": "Treatment of cutaneous epithelioma.", "content": "Treatment of cutaneous epithelioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987142"}
{"pmid": "20987143", "title": "Cutaneous cancer from the point of view of the radiologist.", "content": "Cutaneous cancer from the point of view of the radiologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987143"}
{"pmid": "20987144", "title": "Radiotherapy of epithelioma of the skin.", "content": "Radiotherapy of epithelioma of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987144"}
{"pmid": "20987146", "title": "Histopathology of cutaneous cancer.", "content": "Histopathology of cutaneous cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987146"}
{"pmid": "20987145", "title": "Gross pathology of cutaneous cancer.", "content": "Gross pathology of cutaneous cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987145"}
{"pmid": "20987147", "title": "An unusual case of warts.", "content": "An unusual case of warts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987147"}
{"pmid": "20987148", "title": "Epidermolysis bullosa simplex of the hands and the feet; a genetic study of the hereditary type.", "content": "Epidermolysis bullosa simplex of the hands and the feet; a genetic study of the hereditary type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987148"}
{"pmid": "20987149", "title": "Intrahepatic obstructive jaundice due to neoarsphenamine; ineffectiveness of therapy.", "content": "Intrahepatic obstructive jaundice due to neoarsphenamine; ineffectiveness of therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987149"}
{"pmid": "20987151", "title": "Optimal zone reaction in the diagnosis and treatment of syphilis.", "content": "Optimal zone reaction in the diagnosis and treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987151"}
{"pmid": "20987150", "title": "Treatment of congenital and of acquired syphilis in infants and in children by penicillin.", "content": "Treatment of congenital and of acquired syphilis in infants and in children by penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987150"}
{"pmid": "20987152", "title": "Molluscum contagiosum treated with sulfadiazine.", "content": "Molluscum contagiosum treated with sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987152"}
{"pmid": "20987153", "title": "Purpura due to iodides; report of a case.", "content": "Purpura due to iodides; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987153"}
{"pmid": "20987154", "title": "Pemphigus vegetans.", "content": "Pemphigus vegetans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987154"}
{"pmid": "20987155", "title": "Pernio with milia.", "content": "Pernio with milia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987155"}
{"pmid": "20987156", "title": "Lichen sclerosus and atrophicus (Hallopeau).", "content": "Lichen sclerosus and atrophicus (Hallopeau).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987156"}
{"pmid": "20987157", "title": "Secondary syphilis: condyloma latum in the nostrils.", "content": "Secondary syphilis: condyloma latum in the nostrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987157"}
{"pmid": "20987158", "title": "Atopic eczema (allergic eczema).", "content": "Atopic eczema (allergic eczema).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987158"}
{"pmid": "20987159", "title": "A case for diagnosis (pityriasis-rosea-like, lichen-planus-like eruption following antisyphilitic therapy?).", "content": "A case for diagnosis (pityriasis-rosea-like, lichen-planus-like eruption following antisyphilitic therapy?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987159"}
{"pmid": "20987160", "title": "Lichen nitidus.", "content": "Lichen nitidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987160"}
{"pmid": "20987161", "title": "Lichen scrofulosorum (tuberculosis lichenoides).", "content": "Lichen scrofulosorum (tuberculosis lichenoides).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987161"}
{"pmid": "20987162", "title": "Epidermolysis bullosa.", "content": "Epidermolysis bullosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987162"}
{"pmid": "20987163", "title": "A case for diagnosis (circumscribed neurodermatitis?).", "content": "A case for diagnosis (circumscribed neurodermatitis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987163"}
{"pmid": "20987164", "title": "Bilateral matured cataracts complicating atopic dermatitis.", "content": "Bilateral matured cataracts complicating atopic dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987164"}
{"pmid": "20987165", "title": "Dermatitis herpetiformis followed by lesions resembling lichen planus.", "content": "Dermatitis herpetiformis followed by lesions resembling lichen planus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987165"}
{"pmid": "20987166", "title": "Parapsoriasis varioliformis.", "content": "Parapsoriasis varioliformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987166"}
{"pmid": "20987167", "title": "Fixed eruption (arsenic; bismuth?).", "content": "Fixed eruption (arsenic; bismuth?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987167"}
{"pmid": "20987168", "title": "A case for diagnosis (pigmentation of lip and buccal mucosa).", "content": "A case for diagnosis (pigmentation of lip and buccal mucosa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987168"}
{"pmid": "20987169", "title": "A case for diagnosis (tuberculoderma?).", "content": "A case for diagnosis (tuberculoderma?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987169"}
{"pmid": "20987170", "title": "Xanthoma tuberosum; keloid; Jacquet posterosive syphiloid.", "content": "Xanthoma tuberosum; keloid; Jacquet posterosive syphiloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987170"}
{"pmid": "20987171", "title": "A case for diagnosis (sarcoid; leprosy?).", "content": "A case for diagnosis (sarcoid; leprosy?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987171"}
{"pmid": "20987173", "title": "Hemangiopericytoma.", "content": "Hemangiopericytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987173"}
{"pmid": "20987172", "title": "Sycosis vulgaris (of ten years' duration).", "content": "Sycosis vulgaris (of ten years' duration).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987172"}
{"pmid": "20987175", "title": "A case for diagnosis (Bowen's disease?).", "content": "A case for diagnosis (Bowen's disease?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987175"}
{"pmid": "20987174", "title": "A case for diagnosis (lichen chronicus simplex with nodular growths).", "content": "A case for diagnosis (lichen chronicus simplex with nodular growths).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987174"}
{"pmid": "20987176", "title": "Extensive lupus vulgaris.", "content": "Extensive lupus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987176"}
{"pmid": "20987177", "title": "Erythema multiforme.", "content": "Erythema multiforme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987177"}
{"pmid": "20987205", "title": "Nutrition and food supply in Germany and Austria.", "content": "Nutrition and food supply in Germany and Austria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987205"}
{"pmid": "20987206", "title": "PRESENT knowledge of the vitamin B-complex in human nutrition. II.", "content": "PRESENT knowledge of the vitamin B-complex in human nutrition. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987206"}
{"pmid": "20987208", "title": "MATERNAL nutrition and fetal development.", "content": "MATERNAL nutrition and fetal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987208"}
{"pmid": "20987207", "title": "FAILURE of pyridoxine therapy in nausea and vomiting of pregnancy.", "content": "FAILURE of pyridoxine therapy in nausea and vomiting of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987207"}
{"pmid": "20987209", "title": "PROTEIN intake and niacin metabolism.", "content": "PROTEIN intake and niacin metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987209"}
{"pmid": "20987210", "title": "PYRIDOXINE in relation to poikilocytosis in dairy cattle.", "content": "PYRIDOXINE in relation to poikilocytosis in dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987210"}
{"pmid": "20987211", "title": "ANTIFATTY liver factor of pancreas.", "content": "ANTIFATTY liver factor of pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987211"}
{"pmid": "20987212", "title": "NUTRITIVE value of fish proteins.", "content": "NUTRITIVE value of fish proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987212"}
{"pmid": "20987214", "title": "WORKMEN'S compensation; horseplay doctrine limited in California.", "content": "WORKMEN'S compensation; horseplay doctrine limited in California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987214"}
{"pmid": "20987213", "title": "The physician and the Federal Narcotic Law.", "content": "The physician and the Federal Narcotic Law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987213"}
{"pmid": "20987217", "title": "Blood transfusion in obstetric practice.", "content": "Blood transfusion in obstetric practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987217"}
{"pmid": "20987216", "title": "Blood transfusion in obstetrics.", "content": "Blood transfusion in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987216"}
{"pmid": "20987218", "title": "The gonococcus as a cause of puerperal infection.", "content": "The gonococcus as a cause of puerperal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987218"}
{"pmid": "20987219", "title": "Puerperal sepsis.", "content": "Puerperal sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987219"}
{"pmid": "20987224", "title": "Acute mania attributed to pelvic trauma.", "content": "Acute mania attributed to pelvic trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987224"}
{"pmid": "20987225", "title": "Belladonna, a true polycrest.", "content": "Belladonna, a true polycrest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987225"}
{"pmid": "20987226", "title": "Embarrassed parents.", "content": "Embarrassed parents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987226"}
{"pmid": "20987227", "title": "Drug proving.", "content": "Drug proving.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987227"}
{"pmid": "20987228", "title": "How general and special hospitals can unite in the fight against tuberculosis.", "content": "How general and special hospitals can unite in the fight against tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987228"}
{"pmid": "20987229", "title": "Health care; a moral issue.", "content": "Health care; a moral issue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987229"}
{"pmid": "20987230", "title": "Faculty organization in the school of nursing.", "content": "Faculty organization in the school of nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987230"}
{"pmid": "20987231", "title": "Administrative measures peculiar to the operation of a psychiatric division in a general hospital.", "content": "Administrative measures peculiar to the operation of a psychiatric division in a general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987231"}
{"pmid": "20987233", "title": "American Hospital Association.", "content": "American Hospital Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987233"}
{"pmid": "20987234", "title": "The American Protestant Hospital Association.", "content": "The American Protestant Hospital Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987234"}
{"pmid": "20987232", "title": "The clinic approach to an understanding of community nursing.", "content": "The clinic approach to an understanding of community nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987232"}
{"pmid": "20987235", "title": "The Catholic Hospital Association.", "content": "The Catholic Hospital Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987235"}
{"pmid": "20987237", "title": "How one city operates a complete emergency service.", "content": "How one city operates a complete emergency service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987237"}
{"pmid": "20987236", "title": "One year of success in treating alcoholics.", "content": "One year of success in treating alcoholics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987236"}
{"pmid": "20987238", "title": "The ambulant.", "content": "The ambulant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987238"}
{"pmid": "20987239", "title": "The statistical picture of Michigan hospitals.", "content": "The statistical picture of Michigan hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987239"}
{"pmid": "20987242", "title": "Equipment, in tomorrow's hospital.", "content": "Equipment, in tomorrow's hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987242"}
{"pmid": "20987240", "title": "Payment control through study of risks at admission.", "content": "Payment control through study of risks at admission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987240"}
{"pmid": "20987241", "title": "Mechanics of collecting those borderline accounts.", "content": "Mechanics of collecting those borderline accounts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987241"}
{"pmid": "20987243", "title": "Approach to a cost study of nursing school operations.", "content": "Approach to a cost study of nursing school operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987243"}
{"pmid": "20987244", "title": "A critical analysis of hospital organization.", "content": "A critical analysis of hospital organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987244"}
{"pmid": "20987245", "title": "SYPHILIS control program includes bed rental plan.", "content": "SYPHILIS control program includes bed rental plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987245"}
{"pmid": "20987252", "title": "NEED for a national health program: excerpts from testimony presented before the Senate Committee on Education and Labor.", "content": "NEED for a national health program: excerpts from testimony presented before the Senate Committee on Education and Labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987252"}
{"pmid": "20987272", "title": "The doctor, the patient, and the truth.", "content": "The doctor, the patient, and the truth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987272"}
{"pmid": "20987273", "title": "Legal privilege, on therapeutic grounds, to withhold specific diagnosis from patient sick with serious or fatal illness.", "content": "Legal privilege, on therapeutic grounds, to withhold specific diagnosis from patient sick with serious or fatal illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987273"}
{"pmid": "20987274", "title": "Observations on tuberculosis control in a university hospital.", "content": "Observations on tuberculosis control in a university hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987274"}
{"pmid": "20987275", "title": "Morbidity and mortality in Santo Tomas Internment Camp.", "content": "Morbidity and mortality in Santo Tomas Internment Camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987275"}
{"pmid": "20987276", "title": "Survey of dysentery in prisoners of war.", "content": "Survey of dysentery in prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987276"}
{"pmid": "20987277", "title": "The use of neoarsphenamine in the treatment of amebic dysentery.", "content": "The use of neoarsphenamine in the treatment of amebic dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987277"}
{"pmid": "20987278", "title": "Studies in rheumatic fever; absorption of salicylates.", "content": "Studies in rheumatic fever; absorption of salicylates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987278"}
{"pmid": "20987279", "title": "The treatment of rheumatic fever by roentgen-ray irradiation.", "content": "The treatment of rheumatic fever by roentgen-ray irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987279"}
{"pmid": "20987280", "title": "Reiter's disease: a report of two cases.", "content": "Reiter's disease: a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987280"}
{"pmid": "20987281", "title": "Spontaneous mediastinal emphysema.", "content": "Spontaneous mediastinal emphysema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987281"}
{"pmid": "20987282", "title": "Histoplasmosis of Darling: review and case report with autopsy.", "content": "Histoplasmosis of Darling: review and case report with autopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987282"}
{"pmid": "20987283", "title": "Multiple myeloma simulating hyperparathyroidism.", "content": "Multiple myeloma simulating hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987283"}
{"pmid": "20987284", "title": "A case of cavernous sinus thrombophlebitis successfully treated by combined anticoagulant and chemotherapy.", "content": "A case of cavernous sinus thrombophlebitis successfully treated by combined anticoagulant and chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987284"}
{"pmid": "20987285", "title": "Massive dermoid cyst of the mediastinum, with report of case.", "content": "Massive dermoid cyst of the mediastinum, with report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987285"}
{"pmid": "20987297", "title": "Extrarenal uraemia.", "content": "Extrarenal uraemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987297"}
{"pmid": "20987296", "title": "Paludrine in the treatment of malaria.", "content": "Paludrine in the treatment of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987296"}
{"pmid": "20987298", "title": "Pulmonary exchange during artificial respiration.", "content": "Pulmonary exchange during artificial respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987298"}
{"pmid": "20987299", "title": "Observations on normal body temperatures in North India.", "content": "Observations on normal body temperatures in North India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987299"}
{"pmid": "20987300", "title": "Results of mass radiography of R.A.F. ex-prisoners-of-war from Germany.", "content": "Results of mass radiography of R.A.F. ex-prisoners-of-war from Germany.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987300"}
{"pmid": "20987301", "title": "Gas gangrene of the gallbladder.", "content": "Gas gangrene of the gallbladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987301"}
{"pmid": "20987303", "title": "Cavernous sinus thrombosis treated with penicillin.", "content": "Cavernous sinus thrombosis treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987303"}
{"pmid": "20987302", "title": "A case of concurrent herpes zoster and varicella.", "content": "A case of concurrent herpes zoster and varicella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987302"}
{"pmid": "20987304", "title": "The problem of medical educational films.", "content": "The problem of medical educational films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987304"}
{"pmid": "20987305", "title": "Chemotherapy in malaria.", "content": "Chemotherapy in malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987305"}
{"pmid": "20987306", "title": "Some effects of the rice diet treatment of kidney disease and hypertension.", "content": "Some effects of the rice diet treatment of kidney disease and hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987306"}
{"pmid": "20987307", "title": "Pathology, old and new.", "content": "Pathology, old and new.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987307"}
{"pmid": "20987348", "title": "Modern trends in medicine.", "content": "Modern trends in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987348"}
{"pmid": "20987350", "title": "Generalized scleroderma.", "content": "Generalized scleroderma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987350"}
{"pmid": "20987349", "title": "THE Moukden Medical College in recent years.", "content": "THE Moukden Medical College in recent years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987349"}
{"pmid": "20987354", "title": "The treatment of lymphoid hyperplasia of nasopharynx by radium.", "content": "The treatment of lymphoid hyperplasia of nasopharynx by radium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987354"}
{"pmid": "20987355", "title": "Prognostic signs in experimental hemorrhagic shock.", "content": "Prognostic signs in experimental hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987355"}
{"pmid": "20987356", "title": "Thrombocytopenic purpura in pregnancy; treatment by splenectomy and cesarean section; report of a case.", "content": "Thrombocytopenic purpura in pregnancy; treatment by splenectomy and cesarean section; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987356"}
{"pmid": "20987357", "title": "Practical considerations in the management of diabetes mellitus.", "content": "Practical considerations in the management of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987357"}
{"pmid": "20987358", "title": "Nervousness.", "content": "Nervousness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987358"}
{"pmid": "20987359", "title": "Pain and fever arising from the common bile duct and not associated with jaundice; report of 2 cases of choledocholithiasis treated by choledochostomy and 1 of post-cholecystectomy biliary dyskinesia relieved by vagotomy.", "content": "Pain and fever arising from the common bile duct and not associated with jaundice; report of 2 cases of choledocholithiasis treated by choledochostomy and 1 of post-cholecystectomy biliary dyskinesia relieved by vagotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987359"}
{"pmid": "20987360", "title": "The control of hemorrhage in otolaryngology.", "content": "The control of hemorrhage in otolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987360"}
{"pmid": "20987361", "title": "Ocular torticollis; report of a case.", "content": "Ocular torticollis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987361"}
{"pmid": "20987362", "title": "Climacteric, male and female.", "content": "Climacteric, male and female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987362"}
{"pmid": "20987363", "title": "Curare.", "content": "Curare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987363"}
{"pmid": "20987364", "title": "Acute left ventricular failure.", "content": "Acute left ventricular failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987364"}
{"pmid": "20987374", "title": "The management of backward displacement of the uterus.", "content": "The management of backward displacement of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987374"}
{"pmid": "20987375", "title": "The pathology of rheumatic carditis.", "content": "The pathology of rheumatic carditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987375"}
{"pmid": "20987376", "title": "Notes on rheumatic heart disease; based on 149 case records of patients over 45 years of age.", "content": "Notes on rheumatic heart disease; based on 149 case records of patients over 45 years of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987376"}
{"pmid": "20987377", "title": "Some observations on the pathology of congenital cystic disease of the lung.", "content": "Some observations on the pathology of congenital cystic disease of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987377"}
{"pmid": "20987378", "title": "The technique of refrigeration anaesthesia.", "content": "The technique of refrigeration anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987378"}
{"pmid": "20987379", "title": "The treatment of chronic ulcerative colitis by ileostomy; a report of two cases.", "content": "The treatment of chronic ulcerative colitis by ileostomy; a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987379"}
{"pmid": "20987380", "title": "Two cases of Gaisböck's disease (polycythaemia hypertonica) associated with carcinoma of the kidney.", "content": "Two cases of Gaisböck's disease (polycythaemia hypertonica) associated with carcinoma of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987380"}
{"pmid": "20987381", "title": "Chronic osteomyelitis of the frontal bone, secondary to frontal sinusitis.", "content": "Chronic osteomyelitis of the frontal bone, secondary to frontal sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987381"}
{"pmid": "20987383", "title": "Two cases of chronic traumatic synovitis.", "content": "Two cases of chronic traumatic synovitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987383"}
{"pmid": "20987384", "title": "Abdominal bloating, not due to gas.", "content": "Abdominal bloating, not due to gas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987384"}
{"pmid": "20987385", "title": "Mediastinal cyst, probably hydatid, causing a fatal haematemesis.", "content": "Mediastinal cyst, probably hydatid, causing a fatal haematemesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987385"}
{"pmid": "20987382", "title": "Intracranial abscess, secondary to frontal sinusitis.", "content": "Intracranial abscess, secondary to frontal sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987382"}
{"pmid": "20987386", "title": "Acute-on-chronic small bowel obstruction with stercoral ulcers, requiring resection.", "content": "Acute-on-chronic small bowel obstruction with stercoral ulcers, requiring resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987386"}
{"pmid": "20987387", "title": "A case of subacute bacterial endocarditis treated by intravenous penicillin.", "content": "A case of subacute bacterial endocarditis treated by intravenous penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987387"}
{"pmid": "20987388", "title": "A case of congenital patent ductus arteriosus with infective endocarditis treated by penicillin and ligation of the ductus.", "content": "A case of congenital patent ductus arteriosus with infective endocarditis treated by penicillin and ligation of the ductus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987388"}
{"pmid": "20987389", "title": "Case of delayed union of compound fracture of tibia treated with vitallium plate.", "content": "Case of delayed union of compound fracture of tibia treated with vitallium plate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987389"}
{"pmid": "20987401", "title": "Leukoplakia of the renal pelvis.", "content": "Leukoplakia of the renal pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987401"}
{"pmid": "20987402", "title": "Benign adenoma of the bronchus.", "content": "Benign adenoma of the bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987402"}
{"pmid": "20987403", "title": "Spontaneous rupture of the uterus without apparent cause.", "content": "Spontaneous rupture of the uterus without apparent cause.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987403"}
{"pmid": "20987404", "title": "Acute interstitial cystitis; a new clinical entity; report of a case.", "content": "Acute interstitial cystitis; a new clinical entity; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987404"}
{"pmid": "20987405", "title": "Acute alcoholic hepatitis and pancreatitis; significance of acute epigastric pain in alcoholics.", "content": "Acute alcoholic hepatitis and pancreatitis; significance of acute epigastric pain in alcoholics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987405"}
{"pmid": "20987406", "title": "A case of streptococcus fecalis septicemia treated unsuccessfully with streptomycin.", "content": "A case of streptococcus fecalis septicemia treated unsuccessfully with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987406"}
{"pmid": "20987407", "title": "Disturbance in sugar metabolism in a three months' old infant.", "content": "Disturbance in sugar metabolism in a three months' old infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987407"}
{"pmid": "20987408", "title": "The therapeutic use of chlorophyll; a preliminary report of a series of cases.", "content": "The therapeutic use of chlorophyll; a preliminary report of a series of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987408"}
{"pmid": "20987409", "title": "Psychiatric services in general hospitals.", "content": "Psychiatric services in general hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987409"}
{"pmid": "20987410", "title": "Nutrition and cirrhosis of the liver.", "content": "Nutrition and cirrhosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987410"}
{"pmid": "20987411", "title": "Prevention is the best legal defense.", "content": "Prevention is the best legal defense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987411"}
{"pmid": "20987412", "title": "Vaginal smears for cytologic study; with particular reference to ovarian function and uterine cancer.", "content": "Vaginal smears for cytologic study; with particular reference to ovarian function and uterine cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987412"}
{"pmid": "20987413", "title": "Anti-coagulant therapy.", "content": "Anti-coagulant therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987413"}
{"pmid": "20987414", "title": "New concepts of medical education.", "content": "New concepts of medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987414"}
{"pmid": "20987415", "title": "Atomic physics and medicine.", "content": "Atomic physics and medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987415"}
{"pmid": "20987416", "title": "Occidental beriberi heart disease.", "content": "Occidental beriberi heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987416"}
{"pmid": "20987417", "title": "Delayed serum sickness reaction to penicillin.", "content": "Delayed serum sickness reaction to penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987417"}
{"pmid": "20987418", "title": "Fatal anaphylactic shock; occurrence in identical twins following second injection of diphtheria toxoid and pertussis antigen.", "content": "Fatal anaphylactic shock; occurrence in identical twins following second injection of diphtheria toxoid and pertussis antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987418"}
{"pmid": "20987419", "title": "Remissions in thyrotoxicosis after discontinuing thiouracil.", "content": "Remissions in thyrotoxicosis after discontinuing thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987419"}
{"pmid": "20987420", "title": "Industrial management and occupational cancer.", "content": "Industrial management and occupational cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987420"}
{"pmid": "20987422", "title": "RUTIN.", "content": "RUTIN.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987422"}
{"pmid": "20987421", "title": "Acute syphilitic nephrosis successfully treated with penicillin.", "content": "Acute syphilitic nephrosis successfully treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987421"}
{"pmid": "20987423", "title": "Toxicity of thioglycolic acid used in cold permanent wave process.", "content": "Toxicity of thioglycolic acid used in cold permanent wave process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987423"}
{"pmid": "20987424", "title": "Medical progress in the United States under freedom; presidential address.", "content": "Medical progress in the United States under freedom; presidential address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987424"}
{"pmid": "20987425", "title": "Cancer of endometrium and prolonged estrogen therapy.", "content": "Cancer of endometrium and prolonged estrogen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987425"}
{"pmid": "20987426", "title": "Wood's light fluorescence phenomenon in quinacrine medication.", "content": "Wood's light fluorescence phenomenon in quinacrine medication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987426"}
{"pmid": "20987427", "title": "Fluorescence of nails from quinacrine hydrochloride.", "content": "Fluorescence of nails from quinacrine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987427"}
{"pmid": "20987428", "title": "The artificial menopause and cancer of the breast.", "content": "The artificial menopause and cancer of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987428"}
{"pmid": "20987429", "title": "Bleeding from the cervix after subtotal hysterectomy.", "content": "Bleeding from the cervix after subtotal hysterectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987429"}
{"pmid": "20987430", "title": "TYPHOID in the large cities of the United States in 1945.", "content": "TYPHOID in the large cities of the United States in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987430"}
{"pmid": "20987431", "title": "Klebsiella pneumonia treated with streptomycin.", "content": "Klebsiella pneumonia treated with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987431"}
{"pmid": "20987432", "title": "Allergy to insulin associated with infection.", "content": "Allergy to insulin associated with infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987432"}
{"pmid": "20987433", "title": "BAL (British anti-lewisite) in the treatment of arsenic and mercury poisoning.", "content": "BAL (British anti-lewisite) in the treatment of arsenic and mercury poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987433"}
{"pmid": "20987434", "title": "Bombing and health.", "content": "Bombing and health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987434"}
{"pmid": "20987435", "title": "Recent developments in hospital organization and medical practice that may affect the future.", "content": "Recent developments in hospital organization and medical practice that may affect the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987435"}
{"pmid": "20987436", "title": "Present-day concepts of fracture management.", "content": "Present-day concepts of fracture management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987436"}
{"pmid": "20987437", "title": "The clinical significance of the Rh factor.", "content": "The clinical significance of the Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987437"}
{"pmid": "20987438", "title": "Aviation deafness.", "content": "Aviation deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987438"}
{"pmid": "20987439", "title": "Medical history of Wapello County.", "content": "Medical history of Wapello County.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987439"}
{"pmid": "20987440", "title": "Surgical treatment of achalasia of the esophagus.", "content": "Surgical treatment of achalasia of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987440"}
{"pmid": "20987441", "title": "Postinfluenzal virus pain complexes.", "content": "Postinfluenzal virus pain complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987441"}
{"pmid": "20987442", "title": "Subtotal resection of the pancreas of an eight-year old child for hyperinsulinism.", "content": "Subtotal resection of the pancreas of an eight-year old child for hyperinsulinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987442"}
{"pmid": "20987443", "title": "Cancer of the rectum.", "content": "Cancer of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987443"}
{"pmid": "20987449", "title": "Thymus problem.", "content": "Thymus problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987449"}
{"pmid": "20987450", "title": "Poliomyelitis.", "content": "Poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987450"}
{"pmid": "20987451", "title": "Reinfection with syphilis.", "content": "Reinfection with syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987451"}
{"pmid": "20987456", "title": "When is a sick man a felon?", "content": "When is a sick man a felon?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987456"}
{"pmid": "20987457", "title": "A review of the history of naturopathy.", "content": "A review of the history of naturopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987457"}
{"pmid": "20987452", "title": "Vitamin F and carbamide in calcium metabolism.", "content": "Vitamin F and carbamide in calcium metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987452"}
{"pmid": "20987465", "title": "Acute haematogenous osteomyelitis treated with penicillin.", "content": "Acute haematogenous osteomyelitis treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987465"}
{"pmid": "20987466", "title": "Diet in the treatment of infective hepatitis; therapeutic trial of cysteine and variation of fat-content.", "content": "Diet in the treatment of infective hepatitis; therapeutic trial of cysteine and variation of fat-content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987466"}
{"pmid": "20987467", "title": "Haemopoietic action of 5-methyl uracil (thymine) in tropical sprue.", "content": "Haemopoietic action of 5-methyl uracil (thymine) in tropical sprue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987467"}
{"pmid": "20987453", "title": "Ezcema.", "content": "Ezcema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987453"}
{"pmid": "20987468", "title": "Estimation of paludrine in blood.", "content": "Estimation of paludrine in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987468"}
{"pmid": "20987469", "title": "Salmonella infection in man conveyed by ducks' eggs.", "content": "Salmonella infection in man conveyed by ducks' eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987469"}
{"pmid": "20987455", "title": "What is disease?", "content": "What is disease?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987455"}
{"pmid": "20987454", "title": "Healing by irritation.", "content": "Healing by irritation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987454"}
{"pmid": "20987470", "title": "Anticoagulant action of soya-bean trypsin-inhibitor.", "content": "Anticoagulant action of soya-bean trypsin-inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987470"}
{"pmid": "20987472", "title": "Impacted cherry-stones.", "content": "Impacted cherry-stones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987472"}
{"pmid": "20987471", "title": "Women and men in sport.", "content": "Women and men in sport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987471"}
{"pmid": "20987473", "title": "Man, the object of medicine.", "content": "Man, the object of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987473"}
{"pmid": "20987474", "title": "The enlarging field of the public health officer.", "content": "The enlarging field of the public health officer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987474"}
{"pmid": "20987475", "title": "Comparative safety in five or more repeated cesarian sections.", "content": "Comparative safety in five or more repeated cesarian sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987475"}
{"pmid": "20987476", "title": "ETHICS of ectopic operations [Timothy Lincoln Bouscaren].", "content": "ETHICS of ectopic operations [Timothy Lincoln Bouscaren].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987476"}
{"pmid": "20987477", "title": "Modern concepts of protein metabolism.", "content": "Modern concepts of protein metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987477"}
{"pmid": "20987478", "title": "The relationship between the hormonal imbalance and the accidents of pregnancy in patients with diabetes.", "content": "The relationship between the hormonal imbalance and the accidents of pregnancy in patients with diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987478"}
{"pmid": "20987479", "title": "Clinical manifestations and treatment of shock.", "content": "Clinical manifestations and treatment of shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987479"}
{"pmid": "20987480", "title": "Habitual abortion.", "content": "Habitual abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987480"}
{"pmid": "20987482", "title": "Ornithotic pneumonia.", "content": "Ornithotic pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987482"}
{"pmid": "20987481", "title": "Evaluation of rheumatic fever therapy.", "content": "Evaluation of rheumatic fever therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987481"}
{"pmid": "20987483", "title": "Aleukemic leukemia with histoplasmosis.", "content": "Aleukemic leukemia with histoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987483"}
{"pmid": "20987485", "title": "Program of treatment in tetanus.", "content": "Program of treatment in tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987485"}
{"pmid": "20987484", "title": "Recognition of heart disease; differential diagnosis of right ventricular enlargement.", "content": "Recognition of heart disease; differential diagnosis of right ventricular enlargement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987484"}
{"pmid": "20987486", "title": "The normal roentgenographic cardiac silhouette.", "content": "The normal roentgenographic cardiac silhouette.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987486"}
{"pmid": "20987487", "title": "What is your diagnosis?", "content": "What is your diagnosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987487"}
{"pmid": "20987488", "title": "The challenge of the unknown.", "content": "The challenge of the unknown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987488"}
{"pmid": "20987489", "title": "Streptomycin; a review of the literature.", "content": "Streptomycin; a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987489"}
{"pmid": "20987490", "title": "Intravenous fluids with particular reference to amino acids.", "content": "Intravenous fluids with particular reference to amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987490"}
{"pmid": "20987491", "title": "Foundamentals of child psychology in everyday medical practice.", "content": "Foundamentals of child psychology in everyday medical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987491"}
{"pmid": "20987492", "title": "Free skin grafts.", "content": "Free skin grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987492"}
{"pmid": "20987494", "title": "The relation of organized medicine to the health department in tuberculosis control.", "content": "The relation of organized medicine to the health department in tuberculosis control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987494"}
{"pmid": "20987493", "title": "The use of streptomycin in acute miliary tuberculosis; report of a case.", "content": "The use of streptomycin in acute miliary tuberculosis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987493"}
{"pmid": "20987503", "title": "Effects of strenuous physical education on girls as confirmed by surgery.", "content": "Effects of strenuous physical education on girls as confirmed by surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987503"}
{"pmid": "20987504", "title": "Cancer of the tongue.", "content": "Cancer of the tongue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987504"}
{"pmid": "20987509", "title": "Preliminary report on the use of thiouracil in thyrotoxicosis.", "content": "Preliminary report on the use of thiouracil in thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987509"}
{"pmid": "20987510", "title": "Azotemic pneumonia.", "content": "Azotemic pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987510"}
{"pmid": "20987511", "title": "Case report; an unusual urologic complication of cancer of the rectum.", "content": "Case report; an unusual urologic complication of cancer of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987511"}
{"pmid": "20987512", "title": "Nutrition and the war.", "content": "Nutrition and the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987512"}
{"pmid": "20987513", "title": "The use of the South African frog (Xenopus laevis) in the diagnosis of pregnancy.", "content": "The use of the South African frog (Xenopus laevis) in the diagnosis of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987513"}
{"pmid": "20987514", "title": "The oral lesions of monocytic leukemia; report of a case.", "content": "The oral lesions of monocytic leukemia; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987514"}
{"pmid": "20987515", "title": "Fluorine and dental caries.", "content": "Fluorine and dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987515"}
{"pmid": "20987516", "title": "Sulfonamide nephrosis.", "content": "Sulfonamide nephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987516"}
{"pmid": "20987517", "title": "Benign stricture of esophagus.", "content": "Benign stricture of esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987517"}
{"pmid": "20987518", "title": "The experimental evidence for analgesic properties of antipyretic drugs.", "content": "The experimental evidence for analgesic properties of antipyretic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987518"}
{"pmid": "20987519", "title": "Congenital dilatation of the pulmonary artery due to unequal division of the truncus arteriosus communis.", "content": "Congenital dilatation of the pulmonary artery due to unequal division of the truncus arteriosus communis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987519"}
{"pmid": "20987520", "title": "Coarctation of the aorta with aortic insufficiency.", "content": "Coarctation of the aorta with aortic insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987520"}
{"pmid": "20987521", "title": "Comparison of dihydroergotamine, ergotamine and other agents in the treatment of migraine.", "content": "Comparison of dihydroergotamine, ergotamine and other agents in the treatment of migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987521"}
{"pmid": "20987522", "title": "The treatment of bleeding peptic ulcer.", "content": "The treatment of bleeding peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987522"}
{"pmid": "20987523", "title": "Fatal infectious hepatitis; including a case report.", "content": "Fatal infectious hepatitis; including a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987523"}
{"pmid": "20987524", "title": "Infectious lymphocytosis.", "content": "Infectious lymphocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987524"}
{"pmid": "20987525", "title": "Abdominal puncture as a diagnostic aid.", "content": "Abdominal puncture as a diagnostic aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987525"}
{"pmid": "20987526", "title": "Sulfonamide sensitivity as a cause of abdominal wound separation.", "content": "Sulfonamide sensitivity as a cause of abdominal wound separation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987526"}
{"pmid": "20987527", "title": "The use of single spinal injections for obsterical anesthesia.", "content": "The use of single spinal injections for obsterical anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987527"}
{"pmid": "20987528", "title": "Serum albumin in the supportive therapy in pneumonia of infants.", "content": "Serum albumin in the supportive therapy in pneumonia of infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987528"}
{"pmid": "20987529", "title": "Psychiatry's contribution to peace.", "content": "Psychiatry's contribution to peace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987529"}
{"pmid": "20987542", "title": "Effect of heparin on the prothrombin time.", "content": "Effect of heparin on the prothrombin time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987542"}
{"pmid": "20987543", "title": "Nomenclature of certain gastric operations.", "content": "Nomenclature of certain gastric operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987543"}
{"pmid": "20987545", "title": "Toxicity of solutions of cocaine hydrochloride of various ages.", "content": "Toxicity of solutions of cocaine hydrochloride of various ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987545"}
{"pmid": "20987544", "title": "The effect of penicillin on experimental infections with the virus of venereal lymphogranuloma.", "content": "The effect of penicillin on experimental infections with the virus of venereal lymphogranuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987544"}
{"pmid": "20987547", "title": "Alloxan-induced azotemia in the rat.", "content": "Alloxan-induced azotemia in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987547"}
{"pmid": "20987546", "title": "Protection of dry bacteria by fat against cationic detergents.", "content": "Protection of dry bacteria by fat against cationic detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987546"}
{"pmid": "20987548", "title": "Failure of methionine to reduce nitrogen loss in post-operative herniorrhaphy patients on restricted diet.", "content": "Failure of methionine to reduce nitrogen loss in post-operative herniorrhaphy patients on restricted diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987548"}
{"pmid": "20987550", "title": "Presence of growth inhibiting substance in raw soybeans.", "content": "Presence of growth inhibiting substance in raw soybeans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987550"}
{"pmid": "20987549", "title": "Effectiveness of streptomycin in arthritis of rats.", "content": "Effectiveness of streptomycin in arthritis of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987549"}
{"pmid": "20987551", "title": "Urinary output and phosphorus excretion in human subjects during prolonged exposures at low simulated altitudes.", "content": "Urinary output and phosphorus excretion in human subjects during prolonged exposures at low simulated altitudes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987551"}
{"pmid": "20987552", "title": "Blood agglutinins in filariasis.", "content": "Blood agglutinins in filariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987552"}
{"pmid": "20987553", "title": "Toxicity of nicotinic acid and some of its derivatives.", "content": "Toxicity of nicotinic acid and some of its derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987553"}
{"pmid": "20987555", "title": "Age and species variation in the acute toxicity of alphanaphthyl thiourea.", "content": "Age and species variation in the acute toxicity of alphanaphthyl thiourea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987555"}
{"pmid": "20987554", "title": "Distribution of 2,2 (p-chlorophenyl) 1,1,1 trichlorethane (DDT) in tissues of rats after its ingestion.", "content": "Distribution of 2,2 (p-chlorophenyl) 1,1,1 trichlorethane (DDT) in tissues of rats after its ingestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987554"}
{"pmid": "20987556", "title": "Bactericidal action of streptomycin.", "content": "Bactericidal action of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987556"}
{"pmid": "20987557", "title": "A procedure for testing sterility of concentrated streptomycin solutions.", "content": "A procedure for testing sterility of concentrated streptomycin solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987557"}
{"pmid": "20987558", "title": "Buffers in the range of pH 6.5 to 9.6.", "content": "Buffers in the range of pH 6.5 to 9.6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987558"}
{"pmid": "20987559", "title": "Therapeutic effectiveness of single oral doses of penicillin.", "content": "Therapeutic effectiveness of single oral doses of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987559"}
{"pmid": "20987560", "title": "Adenosine triphosphatase activity and weight of corpora lutea during reproductive cycle of the rat.", "content": "Adenosine triphosphatase activity and weight of corpora lutea during reproductive cycle of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987560"}
{"pmid": "20987561", "title": "Effect of prolonged wakefulness on the urinary excretion of 17-ketosteroids.", "content": "Effect of prolonged wakefulness on the urinary excretion of 17-ketosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987561"}
{"pmid": "20987562", "title": "Subtilin; antibiotic produced by Bacillus subtilis; effect on type III pneumococcus in mice.", "content": "Subtilin; antibiotic produced by Bacillus subtilis; effect on type III pneumococcus in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987562"}
{"pmid": "20987564", "title": "Measured dose of gamma hexachlorocyclohexane (y 666) required to kill flies and cockroaches, and a comparison with DDT.", "content": "Measured dose of gamma hexachlorocyclohexane (y 666) required to kill flies and cockroaches, and a comparison with DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987564"}
{"pmid": "20987563", "title": "Effect of anterior pituitary growth hormone on urinary nitrogen loss following fracture.", "content": "Effect of anterior pituitary growth hormone on urinary nitrogen loss following fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987563"}
{"pmid": "20987565", "title": "Type-specific capsular swelling of meningococci by chicken antiserum.", "content": "Type-specific capsular swelling of meningococci by chicken antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987565"}
{"pmid": "20987567", "title": "Sulfonamide and penicillin resistance of group A hemolytic streptococci.", "content": "Sulfonamide and penicillin resistance of group A hemolytic streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987567"}
{"pmid": "20987566", "title": "The activity of anionic surface active compounds in producing vascular obliteration.", "content": "The activity of anionic surface active compounds in producing vascular obliteration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987566"}
{"pmid": "20987568", "title": "Effect of atropine, testosterone and pitressin on experimental myocardial infarction.", "content": "Effect of atropine, testosterone and pitressin on experimental myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987568"}
{"pmid": "20987569", "title": "The flow of blood supplying the cardiac atria.", "content": "The flow of blood supplying the cardiac atria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987569"}
{"pmid": "20987570", "title": "Pyroninophilic structures of liver cells in carbon tetrachloride poisoning.", "content": "Pyroninophilic structures of liver cells in carbon tetrachloride poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987570"}
{"pmid": "20987572", "title": "Bed-side agglutination test with whole blood for rapid diagnosis of tularemia.", "content": "Bed-side agglutination test with whole blood for rapid diagnosis of tularemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987572"}
{"pmid": "20987571", "title": "Histamine antagonists; comparison of benadryl and pyribenzamine in histamine and anaphylactic shock.", "content": "Histamine antagonists; comparison of benadryl and pyribenzamine in histamine and anaphylactic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987571"}
{"pmid": "20987573", "title": "Some pharmacological properties of the monoanilide of aconitic acid.", "content": "Some pharmacological properties of the monoanilide of aconitic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987573"}
{"pmid": "20987574", "title": "Starch reaction as aid in identification of causative agent of European blastomycosis.", "content": "Starch reaction as aid in identification of causative agent of European blastomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987574"}
{"pmid": "20987575", "title": "Histochemical distribution of alkaline phosphatase in dog liver after experimental biliary obstruction.", "content": "Histochemical distribution of alkaline phosphatase in dog liver after experimental biliary obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987575"}
{"pmid": "20987576", "title": "Morphologic effects of DDT on nerve endings, neurosomes, and fiber types in voluntary muscles.", "content": "Morphologic effects of DDT on nerve endings, neurosomes, and fiber types in voluntary muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987576"}
{"pmid": "20987577", "title": "Diffusion of sulfonamides and penicillin into fibrin.", "content": "Diffusion of sulfonamides and penicillin into fibrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987577"}
{"pmid": "20987580", "title": "Effects of calcium deficiency and pyridoxin deficiency on thymic atrophy (accidental involution).", "content": "Effects of calcium deficiency and pyridoxin deficiency on thymic atrophy (accidental involution).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987580"}
{"pmid": "20987578", "title": "Serum levels after repository injections of penicillin.", "content": "Serum levels after repository injections of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987578"}
{"pmid": "20987579", "title": "Suppression of circulating antibodies in pyridoxin deficiency.", "content": "Suppression of circulating antibodies in pyridoxin deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987579"}
{"pmid": "20987583", "title": "The use of x-rays for the investigations of injuries to bones and joints.", "content": "The use of x-rays for the investigations of injuries to bones and joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987583"}
{"pmid": "20987585", "title": "Vesico-vaginal fistula.", "content": "Vesico-vaginal fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987585"}
{"pmid": "20987584", "title": "Functional bleeding of uterus.", "content": "Functional bleeding of uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987584"}
{"pmid": "20987587", "title": "Acute endocarditis.", "content": "Acute endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987587"}
{"pmid": "20987586", "title": "Case of possible subacute endocarditis.", "content": "Case of possible subacute endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987586"}
{"pmid": "20987588", "title": "Autopsy report; case of a 13-year-old girl suffering from attacks of recurrent ascites.", "content": "Autopsy report; case of a 13-year-old girl suffering from attacks of recurrent ascites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987588"}
{"pmid": "20987589", "title": "Esophageal bronchial fistula.", "content": "Esophageal bronchial fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987589"}
{"pmid": "20987590", "title": "Diabetes and pregnancy.", "content": "Diabetes and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987590"}
{"pmid": "20987591", "title": "Buerger's disease.", "content": "Buerger's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987591"}
{"pmid": "20987592", "title": "Pathological fracture of right femur.", "content": "Pathological fracture of right femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987592"}
{"pmid": "20987593", "title": "Unilateral lipodystrophy.", "content": "Unilateral lipodystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987593"}
{"pmid": "20987594", "title": "Infectious jaundice.", "content": "Infectious jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987594"}
{"pmid": "20987596", "title": "A pseudohermaphrodite; a brief discussion.", "content": "A pseudohermaphrodite; a brief discussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987596"}
{"pmid": "20987595", "title": "Physiology of the liver and biliary apparatus.", "content": "Physiology of the liver and biliary apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987595"}
{"pmid": "20987597", "title": "Adenocarcinoma of the lower third of the esophagus.", "content": "Adenocarcinoma of the lower third of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987597"}
{"pmid": "20987598", "title": "Adenocarcinoma of the thyroid gland.", "content": "Adenocarcinoma of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987598"}
{"pmid": "20987599", "title": "Agranulocytic angina.", "content": "Agranulocytic angina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987599"}
{"pmid": "20987600", "title": "The changing scene in surgery.", "content": "The changing scene in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987600"}
{"pmid": "20987601", "title": "Pneumoencephalography in the diagnosis of cerebral degenerative disease.", "content": "Pneumoencephalography in the diagnosis of cerebral degenerative disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987601"}
{"pmid": "20987602", "title": "The management of the common medical emergencies arising in young infants.", "content": "The management of the common medical emergencies arising in young infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987602"}
{"pmid": "20987603", "title": "The rationale of radiotherapy.", "content": "The rationale of radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987603"}
{"pmid": "20987604", "title": "Duelling.", "content": "Duelling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987604"}
{"pmid": "20987605", "title": "Gastric carcinoma as seen in the veteran.", "content": "Gastric carcinoma as seen in the veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987605"}
{"pmid": "20987606", "title": "Electrocardiography.", "content": "Electrocardiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987606"}
{"pmid": "20987607", "title": "Some practical aspects of carcinoma of the colon and rectum.", "content": "Some practical aspects of carcinoma of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987607"}
{"pmid": "20987621", "title": "Recent studies in the prevention of certain infectious diseases.", "content": "Recent studies in the prevention of certain infectious diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987621"}
{"pmid": "20987622", "title": "A device for holding intranasal tubes.", "content": "A device for holding intranasal tubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987622"}
{"pmid": "20987631", "title": "Allergic rhinitis; seasonal type.", "content": "Allergic rhinitis; seasonal type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987631"}
{"pmid": "20987632", "title": "Malaria as observed in North Africa and Italy.", "content": "Malaria as observed in North Africa and Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987632"}
{"pmid": "20987633", "title": "The use of infra-red and ultraviolet lights in general practice.", "content": "The use of infra-red and ultraviolet lights in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987633"}
{"pmid": "20987634", "title": "The hospitals' responsibility to the public.", "content": "The hospitals' responsibility to the public.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987634"}
{"pmid": "20987651", "title": "The significance of comprehensive medical care.", "content": "The significance of comprehensive medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987651"}
{"pmid": "20987652", "title": "Dental research.", "content": "Dental research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987652"}
{"pmid": "20987653", "title": "Oral surgical procedures.", "content": "Oral surgical procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987653"}
{"pmid": "20987654", "title": "New Zealand food habits.", "content": "New Zealand food habits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987654"}
{"pmid": "20987655", "title": "Oral hygiene in dental health.", "content": "Oral hygiene in dental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987655"}
{"pmid": "20987656", "title": "Impression materials.", "content": "Impression materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987656"}
{"pmid": "20987657", "title": "Positive amalgam technic.", "content": "Positive amalgam technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987657"}
{"pmid": "20987658", "title": "Acrylic eye prosthesis.", "content": "Acrylic eye prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987658"}
{"pmid": "20987659", "title": "Hydro-colloidal impression.", "content": "Hydro-colloidal impression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987659"}
{"pmid": "20987660", "title": "Mistakes in nursing.", "content": "Mistakes in nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987660"}
{"pmid": "20987665", "title": "Secondary electron emission from oxide-coated cathodes.", "content": "Secondary electron emission from oxide-coated cathodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987665"}
{"pmid": "20987666", "title": "Indium, a newcomer in the field of commercial metals.", "content": "Indium, a newcomer in the field of commercial metals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987666"}
{"pmid": "20987667", "title": "Establishment of cytochemical techniques.", "content": "Establishment of cytochemical techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987667"}
{"pmid": "20987668", "title": "Mechanism of formation of ether, using the heavy oxygen isotope 180 as a tracer element.", "content": "Mechanism of formation of ether, using the heavy oxygen isotope 180 as a tracer element.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987668"}
{"pmid": "20987669", "title": "Nutritional value of high-extraction wheat meals.", "content": "Nutritional value of high-extraction wheat meals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987669"}
{"pmid": "20987670", "title": "Mode of entrance of sodium into the aqueous humor.", "content": "Mode of entrance of sodium into the aqueous humor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987670"}
{"pmid": "20987671", "title": "Constitution of hair melanins.", "content": "Constitution of hair melanins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987671"}
{"pmid": "20987672", "title": "Lipoid morphology of the tubercle.", "content": "Lipoid morphology of the tubercle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987672"}
{"pmid": "20987674", "title": "SOCIAL problems of re-settlement.", "content": "SOCIAL problems of re-settlement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987674"}
{"pmid": "20987673", "title": "A method for observing the life-cycle of Melophagus ovinus (Linn.).", "content": "A method for observing the life-cycle of Melophagus ovinus (Linn.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987673"}
{"pmid": "20987675", "title": "The multiplicity of foramina mentalia in a human mandible from the copper age of Anatolia.", "content": "The multiplicity of foramina mentalia in a human mandible from the copper age of Anatolia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987675"}
{"pmid": "20987676", "title": "Prosthetic group of glucose exidase (notatin).", "content": "Prosthetic group of glucose exidase (notatin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987676"}
{"pmid": "20987677", "title": "Histochemical demonstration of acid polysaccharides in animal tissues.", "content": "Histochemical demonstration of acid polysaccharides in animal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987677"}
{"pmid": "20987678", "title": "Effect of sulphadiazine on the metabolism on aneurin in animals.", "content": "Effect of sulphadiazine on the metabolism on aneurin in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987678"}
{"pmid": "20987679", "title": "Mechanism of colour discrimination and a new type of colour blindness.", "content": "Mechanism of colour discrimination and a new type of colour blindness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987679"}
{"pmid": "20987680", "title": "Foveal colour sensitivity.", "content": "Foveal colour sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987680"}
{"pmid": "20987681", "title": "Vernalization of crops cultivated in India.", "content": "Vernalization of crops cultivated in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987681"}
{"pmid": "20987682", "title": "Sex differentiation in Amphibia.", "content": "Sex differentiation in Amphibia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987682"}
{"pmid": "20987683", "title": "Atomic energy and its implications.", "content": "Atomic energy and its implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987683"}
{"pmid": "20987685", "title": "MICROBIOLOGY of retting.", "content": "MICROBIOLOGY of retting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987685"}
{"pmid": "20987684", "title": "Ecology and the study of climate.", "content": "Ecology and the study of climate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987684"}
{"pmid": "20987686", "title": "Observations on the administration of BAL-intrav to man.", "content": "Observations on the administration of BAL-intrav to man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987686"}
{"pmid": "20987687", "title": "Inactivation of antibacterial substances with cysteine.", "content": "Inactivation of antibacterial substances with cysteine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987687"}
{"pmid": "20987688", "title": "Hydrated cellulose from jute fibre.", "content": "Hydrated cellulose from jute fibre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987688"}
{"pmid": "20987689", "title": "Two relativistic models of Dirac's electron.", "content": "Two relativistic models of Dirac's electron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987689"}
{"pmid": "20987691", "title": "Communication between the dorsal edge of the mantle and the stomach of Tridacna.", "content": "Communication between the dorsal edge of the mantle and the stomach of Tridacna.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987691"}
{"pmid": "20987690", "title": "Induction of gigas forms of Penicillium notatum by treatment with camphor vapour.", "content": "Induction of gigas forms of Penicillium notatum by treatment with camphor vapour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987690"}
{"pmid": "20987692", "title": "Origin of language.", "content": "Origin of language.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987692"}
{"pmid": "20987693", "title": "PHYSICAL properties of mica.", "content": "PHYSICAL properties of mica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987693"}
{"pmid": "20987694", "title": "Varieties and mating types in Paramecium bursaria; new variety and types, from England, Ireland, and Czechoslovakia.", "content": "Varieties and mating types in Paramecium bursaria; new variety and types, from England, Ireland, and Czechoslovakia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987694"}
{"pmid": "20987695", "title": "Reverse-mutation and adaptation in leucineless Neurospora.", "content": "Reverse-mutation and adaptation in leucineless Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987695"}
{"pmid": "20987696", "title": "The multiple factor theory of the control of respiratory ventilation.", "content": "The multiple factor theory of the control of respiratory ventilation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987696"}
{"pmid": "20987697", "title": "Radioactivation of colloidal gamma ferric oxide.", "content": "Radioactivation of colloidal gamma ferric oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987697"}
{"pmid": "20987698", "title": "The age factor in adaptability of a sarcoma virus to other animal species.", "content": "The age factor in adaptability of a sarcoma virus to other animal species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987698"}
{"pmid": "20987699", "title": "The effects of sex hormones on the copulatory behavior of senile white rats.", "content": "The effects of sex hormones on the copulatory behavior of senile white rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987699"}
{"pmid": "20987700", "title": "The war and biological sciences in Japan.", "content": "The war and biological sciences in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987700"}
{"pmid": "20987701", "title": "A useful selective bactericidal property of tergitol-7.", "content": "A useful selective bactericidal property of tergitol-7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987701"}
{"pmid": "20987702", "title": "A method for continuous parenteral administration of penicillin and other drugs.", "content": "A method for continuous parenteral administration of penicillin and other drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987702"}
{"pmid": "20987703", "title": "New units for the measurement of radioactivity.", "content": "New units for the measurement of radioactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987703"}
{"pmid": "20987704", "title": "Thyroid adenomas in rats receiving selenium.", "content": "Thyroid adenomas in rats receiving selenium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987704"}
{"pmid": "20987705", "title": "The property of certain calcium silicates to impart supersaturation of CaCO3 to carbonatated water extractions.", "content": "The property of certain calcium silicates to impart supersaturation of CaCO3 to carbonatated water extractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987705"}
{"pmid": "20987706", "title": "The habitat of the snail host of Schistosoma japonicum in the Philippines.", "content": "The habitat of the snail host of Schistosoma japonicum in the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987706"}
{"pmid": "20987707", "title": "Reduction of sympathetic synaptic transmission as an index of inhibition at adrenergic junctions in general.", "content": "Reduction of sympathetic synaptic transmission as an index of inhibition at adrenergic junctions in general.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987707"}
{"pmid": "20987708", "title": "Mixtures of solid amino acids for microbiological amino acid assay.", "content": "Mixtures of solid amino acids for microbiological amino acid assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987708"}
{"pmid": "20987709", "title": "Demonstration of the bronchial tree and pulmonary blood vessels in the fetal.", "content": "Demonstration of the bronchial tree and pulmonary blood vessels in the fetal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987709"}
{"pmid": "20987710", "title": "Commercial fertilizer in the culture of fresh-water algae.", "content": "Commercial fertilizer in the culture of fresh-water algae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987710"}
{"pmid": "20987711", "title": "Misuse of the Linnaean system of nomenclature.", "content": "Misuse of the Linnaean system of nomenclature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987711"}
{"pmid": "20987712", "title": "Penicillin action on the germination of seeds.", "content": "Penicillin action on the germination of seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987712"}
{"pmid": "20987713", "title": "Orthopsychiatry and world harmony.", "content": "Orthopsychiatry and world harmony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987713"}
{"pmid": "20987714", "title": "Symposium, 1946; preparation of psychiatrists for practice, teaching, and research.", "content": "Symposium, 1946; preparation of psychiatrists for practice, teaching, and research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987714"}
{"pmid": "20987715", "title": "Symposium, 1946; presidential address.", "content": "Symposium, 1946; presidential address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987715"}
{"pmid": "20987716", "title": "Psychiatry of today and future expectations.", "content": "Psychiatry of today and future expectations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987716"}
{"pmid": "20987717", "title": "Psychodynamics as a basic science.", "content": "Psychodynamics as a basic science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987717"}
{"pmid": "20987718", "title": "Training principles in psychosomatic medicine.", "content": "Training principles in psychosomatic medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987718"}
{"pmid": "20987719", "title": "Training for teaching psychiatry.", "content": "Training for teaching psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987719"}
{"pmid": "20987720", "title": "Training principles in the use of social service.", "content": "Training principles in the use of social service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987720"}
{"pmid": "20987721", "title": "Training in psychoanalysis.", "content": "Training in psychoanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987721"}
{"pmid": "20987722", "title": "Training in child psychiatry.", "content": "Training in child psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987722"}
{"pmid": "20987723", "title": "The psychologist's contribution to the training of psychiatrists.", "content": "The psychologist's contribution to the training of psychiatrists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987723"}
{"pmid": "20987724", "title": "Symposium, 1946; summary.", "content": "Symposium, 1946; summary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987724"}
{"pmid": "20987725", "title": "A program of training in psychiatry to break the bottleneck in rehabilitation.", "content": "A program of training in psychiatry to break the bottleneck in rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987725"}
{"pmid": "20987726", "title": "Attitudes and prognosis of naval psychiatric dischargees.", "content": "Attitudes and prognosis of naval psychiatric dischargees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987726"}
{"pmid": "20987727", "title": "The childhood and adolescent adjustment of Negro psychiatric casualties.", "content": "The childhood and adolescent adjustment of Negro psychiatric casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987727"}
{"pmid": "20987728", "title": "The German anti-Nazi; a case study.", "content": "The German anti-Nazi; a case study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987728"}
{"pmid": "20987729", "title": "Homicide and attempted suicide; a Rorschach study.", "content": "Homicide and attempted suicide; a Rorschach study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987729"}
{"pmid": "20987730", "title": "Rehabilitation of a tuberculous prostitute through social case work.", "content": "Rehabilitation of a tuberculous prostitute through social case work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987730"}
{"pmid": "20987731", "title": "The psychiatrically immunizing effect of combat wounds.", "content": "The psychiatrically immunizing effect of combat wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987731"}
{"pmid": "20987732", "title": "ARMY psychiatric nomenclature.", "content": "ARMY psychiatric nomenclature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987732"}
{"pmid": "20987733", "title": "History of the development of neuropsychiatry in the European theatre of operations.", "content": "History of the development of neuropsychiatry in the European theatre of operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987733"}
{"pmid": "20987734", "title": "Logistics of the neuropsychiatric problem of the Army.", "content": "Logistics of the neuropsychiatric problem of the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987734"}
{"pmid": "20987735", "title": "Problems confronting psychiatry in the Army convalescent hospital.", "content": "Problems confronting psychiatry in the Army convalescent hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987735"}
{"pmid": "20987736", "title": "Army consultation services (mental hygiene clinics).", "content": "Army consultation services (mental hygiene clinics).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987736"}
{"pmid": "20987737", "title": "The morale of troops on occupation duty.", "content": "The morale of troops on occupation duty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987737"}
{"pmid": "20987738", "title": "Commitment of the mentally ill.", "content": "Commitment of the mentally ill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987738"}
{"pmid": "20987740", "title": "Shock therapy in psychoses complicated by pregnancy; report of two cases.", "content": "Shock therapy in psychoses complicated by pregnancy; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987740"}
{"pmid": "20987739", "title": "The constitutional anhedonic personality.", "content": "The constitutional anhedonic personality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987739"}
{"pmid": "20987741", "title": "Combined shock at corpus luteum hormone therapy.", "content": "Combined shock at corpus luteum hormone therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987741"}
{"pmid": "20987742", "title": "Occupational hazards and psychoses of psychiatrists.", "content": "Occupational hazards and psychoses of psychiatrists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987742"}
{"pmid": "20987743", "title": "The electroencephalogram and psychophysiological regulation in the brain.", "content": "The electroencephalogram and psychophysiological regulation in the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987743"}
{"pmid": "20987744", "title": "Effects of sedative drugs on the electroencephalogram.", "content": "Effects of sedative drugs on the electroencephalogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987744"}
{"pmid": "20987745", "title": "The toxicity of atabrine to the central nervous system.", "content": "The toxicity of atabrine to the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987745"}
{"pmid": "20987746", "title": "Psychiatry has growing pains.", "content": "Psychiatry has growing pains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987746"}
{"pmid": "20987747", "title": "Classification and reallocation of exhaustion casualties in a theatre of war.", "content": "Classification and reallocation of exhaustion casualties in a theatre of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987747"}
{"pmid": "20987748", "title": "Marihuana and aggressive crime.", "content": "Marihuana and aggressive crime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987748"}
{"pmid": "20987749", "title": "Review of psychiatric progress in South America during 1944.", "content": "Review of psychiatric progress in South America during 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987749"}
{"pmid": "20987750", "title": "INSULIN and electroshock therapy in Ontari hospitals.", "content": "INSULIN and electroshock therapy in Ontari hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987750"}
{"pmid": "20987758", "title": "A study of problems encountered by neuropsychiatric soldier patients on their first visit home.", "content": "A study of problems encountered by neuropsychiatric soldier patients on their first visit home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987758"}
{"pmid": "20987759", "title": "Brain facilitation not brain destruction, the aim in electroshock therapy.", "content": "Brain facilitation not brain destruction, the aim in electroshock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987759"}
{"pmid": "20987760", "title": "Pedagogical group psychotherapy.", "content": "Pedagogical group psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987760"}
{"pmid": "20987761", "title": "Hydrocephalus; classification and diagnosis.", "content": "Hydrocephalus; classification and diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987761"}
{"pmid": "20987762", "title": "The genesis of combat fatigue.", "content": "The genesis of combat fatigue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987762"}
{"pmid": "20987763", "title": "Obliterative arteriosclerosis of the brain and the kidney.", "content": "Obliterative arteriosclerosis of the brain and the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987763"}
{"pmid": "20987764", "title": "Two important post-war problems in neurological surgery.", "content": "Two important post-war problems in neurological surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987764"}
{"pmid": "20987794", "title": "The aftermath of war; a review.", "content": "The aftermath of war; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987794"}
{"pmid": "20987795", "title": "Nursing in other lands; Poland.", "content": "Nursing in other lands; Poland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987795"}
{"pmid": "20987804", "title": "Hapamine in the treatment of allergic rhinitis in children.", "content": "Hapamine in the treatment of allergic rhinitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987804"}
{"pmid": "20987805", "title": "The prevention of problem behavior.", "content": "The prevention of problem behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987805"}
{"pmid": "20987806", "title": "The Rh factor.", "content": "The Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987806"}
{"pmid": "20987807", "title": "The nutritional element in the causation of neuroses.", "content": "The nutritional element in the causation of neuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987807"}
{"pmid": "20987808", "title": "Mumps; intraventricular hemorrhage; Cooley's anemia.", "content": "Mumps; intraventricular hemorrhage; Cooley's anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987808"}
{"pmid": "20987800", "title": "BIBLIOGRAPHY on industrial eye problems.", "content": "BIBLIOGRAPHY on industrial eye problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987800"}
{"pmid": "20987798", "title": "A small plant industrial eye program.", "content": "A small plant industrial eye program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987798"}
{"pmid": "20987796", "title": "A simple method of taking earmold impressions.", "content": "A simple method of taking earmold impressions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987796"}
{"pmid": "20987797", "title": "Physiology and pathology of the eustachian tube as observed by direct examination with a catheterizing nasopharyngoscope.", "content": "Physiology and pathology of the eustachian tube as observed by direct examination with a catheterizing nasopharyngoscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987797"}
{"pmid": "20987799", "title": "Sodium sulfacetimide 30 per cent solution in ophthalmology.", "content": "Sodium sulfacetimide 30 per cent solution in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987799"}
{"pmid": "20987814", "title": "DRUG therapy of granuloma.", "content": "DRUG therapy of granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987814"}
{"pmid": "20987815", "title": "NEWER agents for dermatophytosis.", "content": "NEWER agents for dermatophytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987815"}
{"pmid": "20987816", "title": "CLINICAL use of streptomycin.", "content": "CLINICAL use of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987816"}
{"pmid": "20987817", "title": "The pharmacist and veterinary medicine.", "content": "The pharmacist and veterinary medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987817"}
{"pmid": "20987822", "title": "Recent advances in our knowledge of the ergot alkaloids.", "content": "Recent advances in our knowledge of the ergot alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987822"}
{"pmid": "20987823", "title": "PHARMACY in the Hospital Corps.", "content": "PHARMACY in the Hospital Corps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987823"}
{"pmid": "20987824", "title": "ANTIBIOTICS.", "content": "ANTIBIOTICS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987824"}
{"pmid": "20987825", "title": "INFLUENZA virus vaccine.", "content": "INFLUENZA virus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987825"}
{"pmid": "20987826", "title": "Antagonisms and antibiotics.", "content": "Antagonisms and antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987826"}
{"pmid": "20987827", "title": "SPIDER bites and stings.", "content": "SPIDER bites and stings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987827"}
{"pmid": "20987828", "title": "WHAT do you mean, penicillin?", "content": "WHAT do you mean, penicillin?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987828"}
{"pmid": "20987829", "title": "HAY FEVER holiday.", "content": "HAY FEVER holiday.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987829"}
{"pmid": "20987830", "title": "NEW light on diabetes; newer knowledge forces revision of etiologic theories.", "content": "NEW light on diabetes; newer knowledge forces revision of etiologic theories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987830"}
{"pmid": "20987832", "title": "PREGNANT or not?", "content": "PREGNANT or not?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987832"}
{"pmid": "20987831", "title": "PREVENTION and attenuation of measles.", "content": "PREVENTION and attenuation of measles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987831"}
{"pmid": "20987834", "title": "Studies of food preference, appetite and dietary habit; habit, palatability and the diet as factors regulating the selection of food by the rat.", "content": "Studies of food preference, appetite and dietary habit; habit, palatability and the diet as factors regulating the selection of food by the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987834"}
{"pmid": "20987835", "title": "The sparking-over movements in animals and man.", "content": "The sparking-over movements in animals and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987835"}
{"pmid": "20987836", "title": "The copulatory behavior of small mammals.", "content": "The copulatory behavior of small mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987836"}
{"pmid": "20987837", "title": "OZERETZKY tests.", "content": "OZERETZKY tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987837"}
{"pmid": "20987843", "title": "MALARIA at the crossroads in Florida.", "content": "MALARIA at the crossroads in Florida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987843"}
{"pmid": "20987844", "title": "Rheumatic fever.", "content": "Rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987844"}
{"pmid": "20987845", "title": "Health education.", "content": "Health education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987845"}
{"pmid": "20987846", "title": "War-time progress in preventive medicine.", "content": "War-time progress in preventive medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987846"}
{"pmid": "20987847", "title": "The future of paediatrics.", "content": "The future of paediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987847"}
{"pmid": "20987848", "title": "Local authorities and a national health service.", "content": "Local authorities and a national health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987848"}
{"pmid": "20987849", "title": "The present state of hospital rehabilitation.", "content": "The present state of hospital rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987849"}
{"pmid": "20987850", "title": "Outbreak of influenza due to virus A in a military training centre.", "content": "Outbreak of influenza due to virus A in a military training centre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987850"}
{"pmid": "20987851", "title": "An outbreak of gastro-enteritis apparently due to an unusual organism of the dysentery group.", "content": "An outbreak of gastro-enteritis apparently due to an unusual organism of the dysentery group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987851"}
{"pmid": "20987852", "title": "Electrocardiographic alterations in adult rats as a result of acute thiamine deficiency.", "content": "Electrocardiographic alterations in adult rats as a result of acute thiamine deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987852"}
{"pmid": "20987853", "title": "Studies of the acute diarrheal diseases; the sulfonamides in shigellosis.", "content": "Studies of the acute diarrheal diseases; the sulfonamides in shigellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987853"}
{"pmid": "20987854", "title": "Full-time public health positions in local health departments.", "content": "Full-time public health positions in local health departments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987854"}
{"pmid": "20987855", "title": "Tularemia; first case to be reported in Alaska.", "content": "Tularemia; first case to be reported in Alaska.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987855"}
{"pmid": "20987856", "title": "A performance test for rating dishwashing detergents.", "content": "A performance test for rating dishwashing detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987856"}
{"pmid": "20987857", "title": "A serological study of 37 cases of tsutsugamushi disease (scrub typhus) occurring in Burma and the Philippine Islands.", "content": "A serological study of 37 cases of tsutsugamushi disease (scrub typhus) occurring in Burma and the Philippine Islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987857"}
{"pmid": "20987858", "title": "Complement fixation in tsutsugamushi disease (scrub typhus).", "content": "Complement fixation in tsutsugamushi disease (scrub typhus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987858"}
{"pmid": "20987859", "title": "Incidence of poliomyelitis in the United States in 1945.", "content": "Incidence of poliomyelitis in the United States in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987859"}
{"pmid": "20987860", "title": "Plasmodium gallinaceum infection characterized by predominance of exo-erythrocytic forms.", "content": "Plasmodium gallinaceum infection characterized by predominance of exo-erythrocytic forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987860"}
{"pmid": "20987861", "title": "Prevalence of typhus complement-fixing antibodies in human serums in San Antonio, Tex.", "content": "Prevalence of typhus complement-fixing antibodies in human serums in San Antonio, Tex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987861"}
{"pmid": "20987862", "title": "The doctoral program in physical education.", "content": "The doctoral program in physical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987862"}
{"pmid": "20987863", "title": "Action of drugs on efficiency of swimmers.", "content": "Action of drugs on efficiency of swimmers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987863"}
{"pmid": "20987864", "title": "Body weight and the incidence of flat feet.", "content": "Body weight and the incidence of flat feet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987864"}
{"pmid": "20987865", "title": "Evaluative criteria in physical education.", "content": "Evaluative criteria in physical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987865"}
{"pmid": "20987867", "title": "Some findings resulting from the Army Air Forces physical training program.", "content": "Some findings resulting from the Army Air Forces physical training program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987867"}
{"pmid": "20987866", "title": "Petren on the effect of growth and training on the capillarisation of the central nervous system.", "content": "Petren on the effect of growth and training on the capillarisation of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987866"}
{"pmid": "20987888", "title": "Radiological circulation measurements.", "content": "Radiological circulation measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987888"}
{"pmid": "20987891", "title": "Radiographic diagnosis of prolapsed redundant gastric mucosa into the duodenum, with remarks on the clinical significance and treatment.", "content": "Radiographic diagnosis of prolapsed redundant gastric mucosa into the duodenum, with remarks on the clinical significance and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987891"}
{"pmid": "20987892", "title": "Tuberculous arthritis of the shoulder.", "content": "Tuberculous arthritis of the shoulder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987892"}
{"pmid": "20987893", "title": "Interarticular isthmus hiatus (spondylolysis).", "content": "Interarticular isthmus hiatus (spondylolysis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987893"}
{"pmid": "20987894", "title": "The treatment of carcinoma of the cervix.", "content": "The treatment of carcinoma of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987894"}
{"pmid": "20987895", "title": "Some experiences with priodax.", "content": "Some experiences with priodax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987895"}
{"pmid": "20987896", "title": "Pancreatic calculi as a rare cause of intestinal hemorrhage report of a case.", "content": "Pancreatic calculi as a rare cause of intestinal hemorrhage report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987896"}
{"pmid": "20987897", "title": "Roentgen demonstration of a benign intramural tumor (fibromyoma) on the greater curvature of the stomach.", "content": "Roentgen demonstration of a benign intramural tumor (fibromyoma) on the greater curvature of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987897"}
{"pmid": "20987898", "title": "A simple polygraph.", "content": "A simple polygraph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987898"}
{"pmid": "20987899", "title": "Primary Ewing's sarcoma of the spine.", "content": "Primary Ewing's sarcoma of the spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987899"}
{"pmid": "20987900", "title": "Enlarged parietal foramina and similar shadows seen in osteoporosis circumscripta; two cases.", "content": "Enlarged parietal foramina and similar shadows seen in osteoporosis circumscripta; two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987900"}
{"pmid": "20987901", "title": "SKELETAL lesions associated with neurofibromatosis.", "content": "SKELETAL lesions associated with neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987901"}
{"pmid": "20987902", "title": "Management of advanced cancer.", "content": "Management of advanced cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987902"}
{"pmid": "20987903", "title": "Surgical treatment of jejunal ulcer.", "content": "Surgical treatment of jejunal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987903"}
{"pmid": "20987904", "title": "Correction of the congenital protruding ear; a new surgical concept.", "content": "Correction of the congenital protruding ear; a new surgical concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987904"}
{"pmid": "20987906", "title": "Spondylolysis and its relation to spondylolisthesis.", "content": "Spondylolysis and its relation to spondylolisthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987906"}
{"pmid": "20987905", "title": "Comfort in cases of anorectal surgery.", "content": "Comfort in cases of anorectal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987905"}
{"pmid": "20987907", "title": "Duodenal injuries.", "content": "Duodenal injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987907"}
{"pmid": "20987908", "title": "Intravenous sodium pentothal as a basal anesthetic.", "content": "Intravenous sodium pentothal as a basal anesthetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987908"}
{"pmid": "20987909", "title": "Does anterior gastrojejunostomy predispose to development of jejunal ulceration? a study based upon ninety partial gastrectomies.", "content": "Does anterior gastrojejunostomy predispose to development of jejunal ulceration? a study based upon ninety partial gastrectomies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987909"}
{"pmid": "20987910", "title": "Finger amputations.", "content": "Finger amputations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987910"}
{"pmid": "20987911", "title": "Interlaminar spinal anesthesia; an alternative lateral approach for subarachnoid puncture.", "content": "Interlaminar spinal anesthesia; an alternative lateral approach for subarachnoid puncture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987911"}
{"pmid": "20987912", "title": "Further experience with continuous caudal analgesia in obstetrics.", "content": "Further experience with continuous caudal analgesia in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987912"}
{"pmid": "20987913", "title": "Traumatic palmar aneurysm.", "content": "Traumatic palmar aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987913"}
{"pmid": "20987914", "title": "Inspissated blood and the growth of fibromatous uterine tumors; preliminary report.", "content": "Inspissated blood and the growth of fibromatous uterine tumors; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987914"}
{"pmid": "20987915", "title": "Varicosities of the lower extremity; description of an improved method of testing for incompetent communicating veins.", "content": "Varicosities of the lower extremity; description of an improved method of testing for incompetent communicating veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987915"}
{"pmid": "20987917", "title": "Direct inguinal hernia.", "content": "Direct inguinal hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987917"}
{"pmid": "20987916", "title": "A further study of early postoperative ambulation.", "content": "A further study of early postoperative ambulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987916"}
{"pmid": "20987918", "title": "Relief of pain in osteoarthritis of the hip joint.", "content": "Relief of pain in osteoarthritis of the hip joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987918"}
{"pmid": "20987920", "title": "Saphenous vein as an intravenous route.", "content": "Saphenous vein as an intravenous route.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987920"}
{"pmid": "20987919", "title": "Receded chin; its correction with preserved cartilage.", "content": "Receded chin; its correction with preserved cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987919"}
{"pmid": "20987921", "title": "Foreign bodies in and in relation to the thoracic blood vessels and heart; migratory foreign bodies within the blood vascular system.", "content": "Foreign bodies in and in relation to the thoracic blood vessels and heart; migratory foreign bodies within the blood vascular system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987921"}
{"pmid": "20987923", "title": "Spontaneous rupture of the apparently normal spleen.", "content": "Spontaneous rupture of the apparently normal spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987923"}
{"pmid": "20987922", "title": "Congenital atresia of the bile ducts.", "content": "Congenital atresia of the bile ducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987922"}
{"pmid": "20987924", "title": "Avulsion injuries including two cases of avulsion of the scalp.", "content": "Avulsion injuries including two cases of avulsion of the scalp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987924"}
{"pmid": "20987925", "title": "Bilateral recurrent intercarpal subluxation.", "content": "Bilateral recurrent intercarpal subluxation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987925"}
{"pmid": "20987926", "title": "Embryoma of the kidney (Wilms' tumor).", "content": "Embryoma of the kidney (Wilms' tumor).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987926"}
{"pmid": "20987927", "title": "Double gallbladder.", "content": "Double gallbladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987927"}
{"pmid": "20987929", "title": "Osteochondromatosis of the elbow.", "content": "Osteochondromatosis of the elbow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987929"}
{"pmid": "20987930", "title": "Taenia saginata in the appendix.", "content": "Taenia saginata in the appendix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987930"}
{"pmid": "20987928", "title": "Duodenal obstruction complicating cholecystectomy.", "content": "Duodenal obstruction complicating cholecystectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987928"}
{"pmid": "20987931", "title": "Parasitic fibroids; giant parasitic fibroid with sarcomatous degeneration.", "content": "Parasitic fibroids; giant parasitic fibroid with sarcomatous degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987931"}
{"pmid": "20987932", "title": "Pseudocyst of the greater omentum.", "content": "Pseudocyst of the greater omentum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987932"}
{"pmid": "20987933", "title": "New simplified intestinal decompression tube.", "content": "New simplified intestinal decompression tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987933"}
{"pmid": "20987934", "title": "Anaesthesia of recent injuries of the jaw and face.", "content": "Anaesthesia of recent injuries of the jaw and face.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987934"}
{"pmid": "20987935", "title": "A search for the least irritant topical anesthetic.", "content": "A search for the least irritant topical anesthetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987935"}
{"pmid": "20987936", "title": "The histamine-like action of curare and tubocurarine injected intracutaneously and intra-arterially in man.", "content": "The histamine-like action of curare and tubocurarine injected intracutaneously and intra-arterially in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987936"}
{"pmid": "20987937", "title": "Pentothal sodium; its use in the presence of hepatic disease.", "content": "Pentothal sodium; its use in the presence of hepatic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987937"}
{"pmid": "20987938", "title": "The choice of anesthesia in cardiac disease.", "content": "The choice of anesthesia in cardiac disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987938"}
{"pmid": "20987939", "title": "Prothrombin time and anesthesia; a clinical investigation on the effects of ether and spinal anesthesia on the prothrombin level of the blood.", "content": "Prothrombin time and anesthesia; a clinical investigation on the effects of ether and spinal anesthesia on the prothrombin level of the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987939"}
{"pmid": "20987940", "title": "Use of endotracheal tube in therapy of post-traumatic pulmonary secretions.", "content": "Use of endotracheal tube in therapy of post-traumatic pulmonary secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987940"}
{"pmid": "20987941", "title": "Fatal fat embolism; a case report.", "content": "Fatal fat embolism; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987941"}
{"pmid": "20987942", "title": "Abducens nerve palsy following spinal anesthesia.", "content": "Abducens nerve palsy following spinal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987942"}
{"pmid": "20987943", "title": "Convulsions during ether anesthesia controlled by curare (intocostrin).", "content": "Convulsions during ether anesthesia controlled by curare (intocostrin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987943"}
{"pmid": "20987944", "title": "Postoperative heat stroke.", "content": "Postoperative heat stroke.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987944"}
{"pmid": "20987945", "title": "Opportunities in anesthesiology within the Veterans Administration.", "content": "Opportunities in anesthesiology within the Veterans Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987945"}
{"pmid": "20987946", "title": "Exarticulation of the lower extremities for malignant tumors; hip joint disarticulation (with and without deep iliac dissection) and sacro-iliac disarticulation (hemipelvectomy).", "content": "Exarticulation of the lower extremities for malignant tumors; hip joint disarticulation (with and without deep iliac dissection) and sacro-iliac disarticulation (hemipelvectomy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987946"}
{"pmid": "20987947", "title": "Chest wounds in battle casualties.", "content": "Chest wounds in battle casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987947"}
{"pmid": "20987948", "title": "Thoraco-abdominal wounds without abdominal signs, report of two cases.", "content": "Thoraco-abdominal wounds without abdominal signs, report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987948"}
{"pmid": "20987949", "title": "Wounds of the urinary bladder, an analysis of 155 cases.", "content": "Wounds of the urinary bladder, an analysis of 155 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987949"}
{"pmid": "20987950", "title": "The surgical treatment of funnel chest.", "content": "The surgical treatment of funnel chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987950"}
{"pmid": "20987951", "title": "The use of testosterone propionate in the treatment of advanced carcinoma of the breast.", "content": "The use of testosterone propionate in the treatment of advanced carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987951"}
{"pmid": "20987952", "title": "Coincident removal of additional structures in resections for carcinoma of the colon and rectum.", "content": "Coincident removal of additional structures in resections for carcinoma of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987952"}
{"pmid": "20987953", "title": "Choledochus cyst.", "content": "Choledochus cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987953"}
{"pmid": "20987954", "title": "Repeated massive intestinal hemorrhage; report of an unusual case.", "content": "Repeated massive intestinal hemorrhage; report of an unusual case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987954"}
{"pmid": "20987955", "title": "Neurofibroma of the small intestine with massive hemorrhage.", "content": "Neurofibroma of the small intestine with massive hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987955"}
{"pmid": "20987956", "title": "Adenolymphoma of the parotid and submaxillary salivary glands.", "content": "Adenolymphoma of the parotid and submaxillary salivary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987956"}
{"pmid": "20987957", "title": "Pilonidal cysts and sinuses; a technic for excision and primary closure.", "content": "Pilonidal cysts and sinuses; a technic for excision and primary closure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987957"}
{"pmid": "20987958", "title": "Basic principles in geriatric surgery.", "content": "Basic principles in geriatric surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987958"}
{"pmid": "20987959", "title": "Wound healing with low vitamin C level.", "content": "Wound healing with low vitamin C level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987959"}
{"pmid": "20987960", "title": "Modified Bake6s common duct dilators.", "content": "Modified Bake6s common duct dilators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987960"}
{"pmid": "20987975", "title": "Teratoma of the testis.", "content": "Teratoma of the testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987975"}
{"pmid": "20987976", "title": "Some nutritional problems of surgical patients.", "content": "Some nutritional problems of surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987976"}
{"pmid": "20987977", "title": "The place of the anaesthetist in the surgical team.", "content": "The place of the anaesthetist in the surgical team.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987977"}
{"pmid": "20987978", "title": "Prognosis in cancer of the female breast.", "content": "Prognosis in cancer of the female breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987978"}
{"pmid": "20987979", "title": "Frozen sections for the diagnosis of tumour of the breast.", "content": "Frozen sections for the diagnosis of tumour of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987979"}
{"pmid": "20987980", "title": "The problem of carcinoma of the breast in women.", "content": "The problem of carcinoma of the breast in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987980"}
{"pmid": "20987981", "title": "Malignant melanoma of the rectum.", "content": "Malignant melanoma of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987981"}
{"pmid": "20987982", "title": "Stricture of the common bile duct.", "content": "Stricture of the common bile duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987982"}
{"pmid": "20987984", "title": "Urinary calculi.", "content": "Urinary calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987984"}
{"pmid": "20987983", "title": "Discussion on carcinoma of the breast.", "content": "Discussion on carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987983"}
{"pmid": "20987985", "title": "Malunited fractures and dislocations.", "content": "Malunited fractures and dislocations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987985"}
{"pmid": "20987986", "title": "An additional test helping in the diagnosis of chronic cholecystitis.", "content": "An additional test helping in the diagnosis of chronic cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987986"}
{"pmid": "20987987", "title": "Radiation treatment of carcinoma cervix uterii, with follow up report on 72 cases treated during the period 1935-1943.", "content": "Radiation treatment of carcinoma cervix uterii, with follow up report on 72 cases treated during the period 1935-1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987987"}
{"pmid": "20987988", "title": "Irreducible complete prolapse of the rectum.", "content": "Irreducible complete prolapse of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987988"}
{"pmid": "20987989", "title": "A case of chondroma of the scapula.", "content": "A case of chondroma of the scapula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987989"}
{"pmid": "20987990", "title": "Intracavitary (Monaldi) suction.", "content": "Intracavitary (Monaldi) suction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987990"}
{"pmid": "20987991", "title": "Principles of improving inadequate tracheobronchial drainage following trauma to the chest; further problems in the treatment of wet lung.", "content": "Principles of improving inadequate tracheobronchial drainage following trauma to the chest; further problems in the treatment of wet lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987991"}
{"pmid": "20987992", "title": "Cervicomediastinal lymphangioma with chylothorax.", "content": "Cervicomediastinal lymphangioma with chylothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987992"}
{"pmid": "20987993", "title": "A musculoplastic incision for posterior thoracoplasty.", "content": "A musculoplastic incision for posterior thoracoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987993"}
{"pmid": "20987994", "title": "Treatment of syphilitic aneurysms by cellophane wrapping.", "content": "Treatment of syphilitic aneurysms by cellophane wrapping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987994"}
{"pmid": "20987995", "title": "Cystic disease of the lungs and its relationship to bronchiectatic cavities; a study of twenty-two cases.", "content": "Cystic disease of the lungs and its relationship to bronchiectatic cavities; a study of twenty-two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987995"}
{"pmid": "20987996", "title": "The management of thoracic and thoracabdominal wounds in the forward areas in the Sicilian and Italian Campaigns.", "content": "The management of thoracic and thoracabdominal wounds in the forward areas in the Sicilian and Italian Campaigns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987996"}
{"pmid": "20987997", "title": "Foreign body, needle stylet, in the pleural cavity; removal through thoracoscopic procedure.", "content": "Foreign body, needle stylet, in the pleural cavity; removal through thoracoscopic procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987997"}
{"pmid": "20987998", "title": "Symposium on colon surgery; introductory remarks.", "content": "Symposium on colon surgery; introductory remarks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987998"}
{"pmid": "20987999", "title": "Selection of operation and technic of abdominoperineal resection for carcinoma of the rectum.", "content": "Selection of operation and technic of abdominoperineal resection for carcinoma of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20987999"}
{"pmid": "20988000", "title": "Carcinoma of the colon and rectum: site of growth of 1,457 lesions.", "content": "Carcinoma of the colon and rectum: site of growth of 1,457 lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988000"}
{"pmid": "20988001", "title": "The diagnosis of carcinoma of the colon and rectum.", "content": "The diagnosis of carcinoma of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988001"}
{"pmid": "20988002", "title": "Cancer of the rectum; a discussion of preoperative preparation, postoperative complications and colostomy management.", "content": "Cancer of the rectum; a discussion of preoperative preparation, postoperative complications and colostomy management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988002"}
{"pmid": "20988003", "title": "Diagnostic significance of rectal bleeding.", "content": "Diagnostic significance of rectal bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988003"}
{"pmid": "20988004", "title": "The clinical significance of diarrhea.", "content": "The clinical significance of diarrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988004"}
{"pmid": "20988005", "title": "The use of double contrast enemas in lesions of the colon.", "content": "The use of double contrast enemas in lesions of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988005"}
{"pmid": "20988006", "title": "Roentgen diagnostic methods for detection of colonic lesions.", "content": "Roentgen diagnostic methods for detection of colonic lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988006"}
{"pmid": "20988007", "title": "Primary resection of the right colon.", "content": "Primary resection of the right colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988007"}
{"pmid": "20988008", "title": "A discussion of the modified Mikulicz operation for carcinoma of the colon and its technic.", "content": "A discussion of the modified Mikulicz operation for carcinoma of the colon and its technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988008"}
{"pmid": "20988009", "title": "An unusual complication of the Mikulicz type of resection.", "content": "An unusual complication of the Mikulicz type of resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988009"}
{"pmid": "20988010", "title": "Anuria and uremia following surgery of the right colon (ileostomy).", "content": "Anuria and uremia following surgery of the right colon (ileostomy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988010"}
{"pmid": "20988011", "title": "Chronic ulcerative colitis: diagnosis and medical management.", "content": "Chronic ulcerative colitis: diagnosis and medical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988011"}
{"pmid": "20988012", "title": "Chronic ulcerative colitis complicated by carcinoma of the colon and rectum.", "content": "Chronic ulcerative colitis complicated by carcinoma of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988012"}
{"pmid": "20988013", "title": "Congenital megacolon.", "content": "Congenital megacolon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988013"}
{"pmid": "20988014", "title": "Surgical treatment of intestinal tuberculosis.", "content": "Surgical treatment of intestinal tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988014"}
{"pmid": "20988015", "title": "Injuries of the colon and rectum.", "content": "Injuries of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988015"}
{"pmid": "20988016", "title": "Renal function and major surgery.", "content": "Renal function and major surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988016"}
{"pmid": "20988017", "title": "Major surgery in the asthmatic patient.", "content": "Major surgery in the asthmatic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988017"}
{"pmid": "20988018", "title": "Blood transfusion in major surgery: factors of safety.", "content": "Blood transfusion in major surgery: factors of safety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988018"}
{"pmid": "20988019", "title": "Metastasis to bone in gastrointestinal malignancy.", "content": "Metastasis to bone in gastrointestinal malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988019"}
{"pmid": "20988021", "title": "Management of anesthesia in bowel surgery.", "content": "Management of anesthesia in bowel surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988021"}
{"pmid": "20988020", "title": "Complications following large bowel surgery and their management.", "content": "Complications following large bowel surgery and their management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988020"}
{"pmid": "20988022", "title": "The use of curare in anesthesia.", "content": "The use of curare in anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988022"}
{"pmid": "20988023", "title": "The preoperative and postoperative use of sedatives and narcotics in the aged.", "content": "The preoperative and postoperative use of sedatives and narcotics in the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988023"}
{"pmid": "20988025", "title": "Carcinoma of the breast: an analysis of 300 cases.", "content": "Carcinoma of the breast: an analysis of 300 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988025"}
{"pmid": "20988024", "title": "Sarcoma of the breast.", "content": "Sarcoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988024"}
{"pmid": "20988026", "title": "Radiation treatment of carcinoma of the breast.", "content": "Radiation treatment of carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988026"}
{"pmid": "20988027", "title": "The surgical aspects of obstructing lesions of the esophagus.", "content": "The surgical aspects of obstructing lesions of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988027"}
{"pmid": "20988028", "title": "Diaphragmatic hernia; a clinical report of 34 surgically treated cases.", "content": "Diaphragmatic hernia; a clinical report of 34 surgically treated cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988028"}
{"pmid": "20988030", "title": "The repair of traumatic lesions of the facial nerve secondary to war wounds.", "content": "The repair of traumatic lesions of the facial nerve secondary to war wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988030"}
{"pmid": "20988029", "title": "The problems of gastrojejunal ulcer with illustrative case reports.", "content": "The problems of gastrojejunal ulcer with illustrative case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988029"}
{"pmid": "20988031", "title": "The role of minor procedures in the treatment of trigeminal neuralgia.", "content": "The role of minor procedures in the treatment of trigeminal neuralgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988031"}
{"pmid": "20988033", "title": "Local chemotherapy of wounds; tissue toxicity of certain antibacterial substances.", "content": "Local chemotherapy of wounds; tissue toxicity of certain antibacterial substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988033"}
{"pmid": "20988032", "title": "Reflex sympathetic dystrophy.", "content": "Reflex sympathetic dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988032"}
{"pmid": "20988034", "title": "Anomalous innervation of the intrinsic muscles of the hand.", "content": "Anomalous innervation of the intrinsic muscles of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988034"}
{"pmid": "20988035", "title": "Reconstructive operations for benign stricture of the bile ducts.", "content": "Reconstructive operations for benign stricture of the bile ducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988035"}
{"pmid": "20988036", "title": "The repair of nasal defects with the median forehead flap; primary closure of forehead wound.", "content": "The repair of nasal defects with the median forehead flap; primary closure of forehead wound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988036"}
{"pmid": "20988037", "title": "The surgical treatment of acute cholecystitis.", "content": "The surgical treatment of acute cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988037"}
{"pmid": "20988038", "title": "Observations on a concept of inguinal hernia repair.", "content": "Observations on a concept of inguinal hernia repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988038"}
{"pmid": "20988039", "title": "The gastric digestion of living tissue.", "content": "The gastric digestion of living tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988039"}
{"pmid": "20988040", "title": "The local application of nitrofuran compounds with special reference to use on wounds.", "content": "The local application of nitrofuran compounds with special reference to use on wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988040"}
{"pmid": "20988041", "title": "Malignant lesions of the duodenum.", "content": "Malignant lesions of the duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988041"}
{"pmid": "20988042", "title": "Pilonidal sinus; treatment by primary closure.", "content": "Pilonidal sinus; treatment by primary closure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988042"}
{"pmid": "20988043", "title": "The use of penicillin therapy in conjunction with free bone grafting in infected areas.", "content": "The use of penicillin therapy in conjunction with free bone grafting in infected areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988043"}
{"pmid": "20988044", "title": "The structure of the calcaneal tendon (of Achilles) in relation to orthopedic surgery, with additional observations on the plantaris muscle.", "content": "The structure of the calcaneal tendon (of Achilles) in relation to orthopedic surgery, with additional observations on the plantaris muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988044"}
{"pmid": "20988045", "title": "Foreign bodies in, and in relation to, the thoracic blood vessels and heart; techniques for approaching and removing foreign bodies from the chambers of the heart.", "content": "Foreign bodies in, and in relation to, the thoracic blood vessels and heart; techniques for approaching and removing foreign bodies from the chambers of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988045"}
{"pmid": "20988046", "title": "Fractures of the upper end and shaft of the humèrus; a simple conservative method of treatment.", "content": "Fractures of the upper end and shaft of the humèrus; a simple conservative method of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988046"}
{"pmid": "20988054", "title": "Histoplasmosis in Brazil.", "content": "Histoplasmosis in Brazil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988054"}
{"pmid": "20988053", "title": "Isolation of yellow fever virus from African mosquitoes.", "content": "Isolation of yellow fever virus from African mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988053"}
{"pmid": "20988055", "title": "Oral emetine in the treatment of intestinal amebiasis.", "content": "Oral emetine in the treatment of intestinal amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988055"}
{"pmid": "20988057", "title": "A case in which eggs of Schistosoma japonicum were demonstrated in multiple skin lesions.", "content": "A case in which eggs of Schistosoma japonicum were demonstrated in multiple skin lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988057"}
{"pmid": "20988058", "title": "The treatment of schistosomiasis mansoni with urea stibamine (Squibb).", "content": "The treatment of schistosomiasis mansoni with urea stibamine (Squibb).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988058"}
{"pmid": "20988059", "title": "Simplified quantitative methods for hookworm control programs.", "content": "Simplified quantitative methods for hookworm control programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988059"}
{"pmid": "20988047", "title": "THE teaching of physical medicine.", "content": "THE teaching of physical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988047"}
{"pmid": "20988049", "title": "Studies in the incidence of rheumatism among industrial and clerical workers.", "content": "Studies in the incidence of rheumatism among industrial and clerical workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988049"}
{"pmid": "20988060", "title": "Treatment of Hymenolepis nana infection with acranil.", "content": "Treatment of Hymenolepis nana infection with acranil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988060"}
{"pmid": "20988048", "title": "Rheumatism as a social and industrial problem.", "content": "Rheumatism as a social and industrial problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988048"}
{"pmid": "20988061", "title": "Emergency sterilization of drinking water with heteropolar cationic antiseptics; effectiveness against cysts of Endamoeba histolytica.", "content": "Emergency sterilization of drinking water with heteropolar cationic antiseptics; effectiveness against cysts of Endamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988061"}
{"pmid": "20988050", "title": "Removal of industrial dirt from the skin.", "content": "Removal of industrial dirt from the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988050"}
{"pmid": "20988056", "title": "Preliminary report on the evaluation of penicillin in the treatment of yaws.", "content": "Preliminary report on the evaluation of penicillin in the treatment of yaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988056"}
{"pmid": "20988051", "title": "Physical medicine in the treatment of children.", "content": "Physical medicine in the treatment of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988051"}
{"pmid": "20988062", "title": "Precautions by the Army to prevent the introduction of tropical diseases.", "content": "Precautions by the Army to prevent the introduction of tropical diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988062"}
{"pmid": "20988063", "title": "The prognosis and problems in renal tumors.", "content": "The prognosis and problems in renal tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988063"}
{"pmid": "20988064", "title": "Thrombosis of the inferior vena cava associated with malignant renal tumors.", "content": "Thrombosis of the inferior vena cava associated with malignant renal tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988064"}
{"pmid": "20988065", "title": "Abortive therapy for perinephric abscess.", "content": "Abortive therapy for perinephric abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988065"}
{"pmid": "20988066", "title": "Translumbar aortagraphy; its diagnostic value in urology.", "content": "Translumbar aortagraphy; its diagnostic value in urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988066"}
{"pmid": "20988067", "title": "Treatment of carcinoma of the bladder for the past five years with special reference to the closed method of treatment.", "content": "Treatment of carcinoma of the bladder for the past five years with special reference to the closed method of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988067"}
{"pmid": "20988068", "title": "Topical use of clotting agents in surgery of the prostate gland.", "content": "Topical use of clotting agents in surgery of the prostate gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988068"}
{"pmid": "20988069", "title": "Questionable cancer of the prostate gland; clinical versus routine pathologic evidence.", "content": "Questionable cancer of the prostate gland; clinical versus routine pathologic evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988069"}
{"pmid": "20988070", "title": "Primary carcinoma of the prostate of twelve years duration; case report.", "content": "Primary carcinoma of the prostate of twelve years duration; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988070"}
{"pmid": "20988052", "title": "The hospital in relation to functional analysis.", "content": "The hospital in relation to functional analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988052"}
{"pmid": "20988071", "title": "Liver changes and other effects of diethylstilbestrol during treatment of the prostate gland cancer.", "content": "Liver changes and other effects of diethylstilbestrol during treatment of the prostate gland cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988071"}
{"pmid": "20988072", "title": "Hormone therapy in urologic practice.", "content": "Hormone therapy in urologic practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988072"}
{"pmid": "20988073", "title": "Stress incontinence in women.", "content": "Stress incontinence in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988073"}
{"pmid": "20988074", "title": "A clinical and pathological study of the posterior female urethra.", "content": "A clinical and pathological study of the posterior female urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988074"}
{"pmid": "20988075", "title": "Solitary testicular metastasis simulating primary tumor and antedating clinical hypernephroma of the kidney; report of a case.", "content": "Solitary testicular metastasis simulating primary tumor and antedating clinical hypernephroma of the kidney; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988075"}
{"pmid": "20988076", "title": "Erosive and gangrenous balanitis; report of a case.", "content": "Erosive and gangrenous balanitis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988076"}
{"pmid": "20988077", "title": "The treatment of urinary infections with mandelamine (methenamine mandelate); a clinical study of 200 cases.", "content": "The treatment of urinary infections with mandelamine (methenamine mandelate); a clinical study of 200 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988077"}
{"pmid": "20988078", "title": "Retention urethral catheter.", "content": "Retention urethral catheter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988078"}
{"pmid": "20988079", "title": "The new strategy against venereal disease.", "content": "The new strategy against venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988079"}
{"pmid": "20988080", "title": "Wartime lessons in venereal disease control.", "content": "Wartime lessons in venereal disease control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988080"}
{"pmid": "20988081", "title": "A psychological approach to social hygiene for women.", "content": "A psychological approach to social hygiene for women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988081"}
{"pmid": "20988096", "title": "Enzootic bovine haematuria (Haematuria vesicalis).", "content": "Enzootic bovine haematuria (Haematuria vesicalis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988096"}
{"pmid": "20988097", "title": "Tuberculous lesions of swine; survey of lesions found in Eastern Canada.", "content": "Tuberculous lesions of swine; survey of lesions found in Eastern Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988097"}
{"pmid": "20988098", "title": "Avian tuberculosis; observations on chickens infected by subcutaneous inoculation of tuberculous lesions from swine.", "content": "Avian tuberculosis; observations on chickens infected by subcutaneous inoculation of tuberculous lesions from swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988098"}
{"pmid": "20988099", "title": "A case of pseudo-parasitism caused by fungus feeding beetles.", "content": "A case of pseudo-parasitism caused by fungus feeding beetles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988099"}
{"pmid": "20988100", "title": "The sneezing sickness in swine from an epizootic point of view.", "content": "The sneezing sickness in swine from an epizootic point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988100"}
{"pmid": "20988101", "title": "Two species of the nematode genus Setaria Viborg.", "content": "Two species of the nematode genus Setaria Viborg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988101"}
{"pmid": "20988102", "title": "An examination of records of cases of disease, including neoplasmata, of the alimentary system in domesticated animals.", "content": "An examination of records of cases of disease, including neoplasmata, of the alimentary system in domesticated animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988102"}
{"pmid": "20988103", "title": "Various factors that affect milk composition.", "content": "Various factors that affect milk composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988103"}
{"pmid": "20988104", "title": "Swine erysipelas.", "content": "Swine erysipelas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988104"}
{"pmid": "20988105", "title": "Feeding poultry.", "content": "Feeding poultry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988105"}
{"pmid": "20988106", "title": "A note on an outbreak of Baru (Sorghum helipensis) poisoning.", "content": "A note on an outbreak of Baru (Sorghum helipensis) poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988106"}
{"pmid": "20988107", "title": "Successful gastrotomy in a bitch.", "content": "Successful gastrotomy in a bitch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988107"}
{"pmid": "20988108", "title": "Herniotomy in a dog.", "content": "Herniotomy in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988108"}
{"pmid": "20988109", "title": "Caesarean section in a bitch.", "content": "Caesarean section in a bitch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988109"}
{"pmid": "20988110", "title": "Protein therapy in veterinary practice.", "content": "Protein therapy in veterinary practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988110"}
{"pmid": "20988111", "title": "M & B 693 in the treatment of haemorrhagic septicaemia in cattle.", "content": "M & B 693 in the treatment of haemorrhagic septicaemia in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988111"}
{"pmid": "20988112", "title": "Artificial insemination increases fertility.", "content": "Artificial insemination increases fertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988112"}
{"pmid": "20988114", "title": "The status of avian pneumoencephalitis and Newcastle disease in the United States.", "content": "The status of avian pneumoencephalitis and Newcastle disease in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988114"}
{"pmid": "20988115", "title": "Canine chorea due to striocerebellar degeneration of unknown etiology.", "content": "Canine chorea due to striocerebellar degeneration of unknown etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988115"}
{"pmid": "20988113", "title": "Newcastle disease and fowl plague investigations in the war research program.", "content": "Newcastle disease and fowl plague investigations in the war research program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988113"}
{"pmid": "20988116", "title": "Clostridium infection in range animals.", "content": "Clostridium infection in range animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988116"}
{"pmid": "20988117", "title": "Proposed code for the inspection of human food.", "content": "Proposed code for the inspection of human food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988117"}
{"pmid": "20988118", "title": "The chemotherapy of cecal coccidiosis (Eimeria tenella) of chickens; experiments on the use of chemotherapy during the immunizing exposure of chicks.", "content": "The chemotherapy of cecal coccidiosis (Eimeria tenella) of chickens; experiments on the use of chemotherapy during the immunizing exposure of chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988118"}
{"pmid": "20988119", "title": "Hernia in horses and cows.", "content": "Hernia in horses and cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988119"}
{"pmid": "20988120", "title": "Penicillin in peanut oil with 3 per cent beeswax; local use in bovine staphylococcal mastitis.", "content": "Penicillin in peanut oil with 3 per cent beeswax; local use in bovine staphylococcal mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988120"}
{"pmid": "20988121", "title": "Aujeszky's disease in Wisconsin.", "content": "Aujeszky's disease in Wisconsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988121"}
{"pmid": "20988122", "title": "A preliminary report on use of lead arsenate for removal of the sheep tapeworm, Moniezia expansa.", "content": "A preliminary report on use of lead arsenate for removal of the sheep tapeworm, Moniezia expansa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988122"}
{"pmid": "20988123", "title": "Sulfamerazine in the treatment of pullorum disease.", "content": "Sulfamerazine in the treatment of pullorum disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988123"}
{"pmid": "20988124", "title": "Leucocytic changes in the bovine animal 18 hours after the subcutaneous injection of tuberculin.", "content": "Leucocytic changes in the bovine animal 18 hours after the subcutaneous injection of tuberculin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988124"}
{"pmid": "20988125", "title": "Urinary calculi.", "content": "Urinary calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988125"}
{"pmid": "20988126", "title": "The veterinary status of Greece and UNRRA aid in 1945.", "content": "The veterinary status of Greece and UNRRA aid in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988126"}
{"pmid": "20988127", "title": "The blood picture in cases of retained fetal membranes in cattle.", "content": "The blood picture in cases of retained fetal membranes in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988127"}
{"pmid": "20988128", "title": "The reduction of uterine torsions in parturient cows.", "content": "The reduction of uterine torsions in parturient cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988128"}
{"pmid": "20988129", "title": "PLAGUE, typhus, fleas.", "content": "PLAGUE, typhus, fleas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988129"}
{"pmid": "20988130", "title": "Treatment of small animals in a mixed practice.", "content": "Treatment of small animals in a mixed practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988130"}
{"pmid": "20988131", "title": "Sulfamerazine in veterinary practice.", "content": "Sulfamerazine in veterinary practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988131"}
{"pmid": "20988132", "title": "Fluorine poisoning in a horse.", "content": "Fluorine poisoning in a horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988132"}
{"pmid": "20988133", "title": "Dosages of penicillin for Streptococcus agalactiae mastitis.", "content": "Dosages of penicillin for Streptococcus agalactiae mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988133"}
{"pmid": "20988134", "title": "Observation of swine erysipelas in turkeys (including the public health aspect and possible human cases).", "content": "Observation of swine erysipelas in turkeys (including the public health aspect and possible human cases).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988134"}
{"pmid": "20988135", "title": "True scurvy in the dog.", "content": "True scurvy in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988135"}
{"pmid": "20988136", "title": "The muting of animals for General Wingate's force operating behind the Japanese lines in Burma.", "content": "The muting of animals for General Wingate's force operating behind the Japanese lines in Burma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988136"}
{"pmid": "20988137", "title": "Dropping of mules by parachute from Dakota aircraft.", "content": "Dropping of mules by parachute from Dakota aircraft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988137"}
{"pmid": "20988138", "title": "An outbreak of foot-and-mouth disease in Austria.", "content": "An outbreak of foot-and-mouth disease in Austria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988138"}
{"pmid": "20988139", "title": "The use of electrical appliances in shrapnel detection.", "content": "The use of electrical appliances in shrapnel detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988139"}
{"pmid": "20988140", "title": "Salmonellosis in ducks at an Army development farm.", "content": "Salmonellosis in ducks at an Army development farm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988140"}
{"pmid": "20988141", "title": "The suitability of Shakapara biscuit as a food for Army animals.", "content": "The suitability of Shakapara biscuit as a food for Army animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988141"}
{"pmid": "20988143", "title": "Observations on various phases of dairy cattle practice.", "content": "Observations on various phases of dairy cattle practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988143"}
{"pmid": "20988144", "title": "The isolation of diphtheroids from apparently normal cows.", "content": "The isolation of diphtheroids from apparently normal cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988144"}
{"pmid": "20988145", "title": "So-called mixed bacterial infections of dogs.", "content": "So-called mixed bacterial infections of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988145"}
{"pmid": "20988146", "title": "Tetanus in a German shepherd.", "content": "Tetanus in a German shepherd.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988146"}
{"pmid": "20988147", "title": "Hand diseases of veterinarians.", "content": "Hand diseases of veterinarians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988147"}
{"pmid": "20988148", "title": "Value of hemograms in the differential diagnosis of diseases of dairy cattle.", "content": "Value of hemograms in the differential diagnosis of diseases of dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988148"}
{"pmid": "20988149", "title": "Acetonemia.", "content": "Acetonemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988149"}
{"pmid": "20988150", "title": "Ovarian dysfunction a cause of milk fever and allied diseases.", "content": "Ovarian dysfunction a cause of milk fever and allied diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988150"}
{"pmid": "20988151", "title": "The efficacy of sodium fluoride in removing ascarids of swine.", "content": "The efficacy of sodium fluoride in removing ascarids of swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988151"}
{"pmid": "20988142", "title": "Field observations and some swine diseases.", "content": "Field observations and some swine diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988142"}
{"pmid": "20988152", "title": "Timing fox matings for maximum production.", "content": "Timing fox matings for maximum production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988152"}
{"pmid": "20988153", "title": "A clinical prophylactic trial with distemperoid virus.", "content": "A clinical prophylactic trial with distemperoid virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988153"}
{"pmid": "20988154", "title": "Acute monocytic leukemia; a case report.", "content": "Acute monocytic leukemia; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988154"}
{"pmid": "20988155", "title": "Engorgement of the rumen in cows.", "content": "Engorgement of the rumen in cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988155"}
{"pmid": "20988166", "title": "AN increasing source of uninspected meat.", "content": "AN increasing source of uninspected meat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988166"}
{"pmid": "20988165", "title": "MIXED bacterial infections in dogs.", "content": "MIXED bacterial infections in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988165"}
{"pmid": "20988167", "title": "Diabetes mellitus in dogs.", "content": "Diabetes mellitus in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988167"}
{"pmid": "20988168", "title": "A veterinarian's experience in the Philippines before and during the Jap occupation.", "content": "A veterinarian's experience in the Philippines before and during the Jap occupation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988168"}
{"pmid": "20988169", "title": "Bovine cesarean section at sea.", "content": "Bovine cesarean section at sea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988169"}
{"pmid": "20988170", "title": "DAIRY cattle practice.", "content": "DAIRY cattle practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988170"}
{"pmid": "20988171", "title": "Artificial insemination in range cattle.", "content": "Artificial insemination in range cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988171"}
{"pmid": "20988172", "title": "DIFFERENTIAL diagnosis of swine erysipelas.", "content": "DIFFERENTIAL diagnosis of swine erysipelas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988172"}
{"pmid": "20988173", "title": "Osteogenic sarcoma of the tibia of a dog.", "content": "Osteogenic sarcoma of the tibia of a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988173"}
{"pmid": "20988174", "title": "Spontaneous rupture of the jugular vein.", "content": "Spontaneous rupture of the jugular vein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988174"}
{"pmid": "20988175", "title": "The management of a veterinary practice.", "content": "The management of a veterinary practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988175"}
{"pmid": "20988176", "title": "The mine detector as an aid to detection of metallic foreign bodies in cattle.", "content": "The mine detector as an aid to detection of metallic foreign bodies in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988176"}
{"pmid": "20988177", "title": "BRUCELLA abortus infection in cattle; agglutination tests.", "content": "BRUCELLA abortus infection in cattle; agglutination tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988177"}
{"pmid": "20988178", "title": "Studies on enzootic staphylococcal infection in lambs associated with tick-bite; the bacteriology of the disease.", "content": "Studies on enzootic staphylococcal infection in lambs associated with tick-bite; the bacteriology of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988178"}
{"pmid": "20988179", "title": "Visual aids in veterinary education.", "content": "Visual aids in veterinary education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988179"}
{"pmid": "20988180", "title": "Rhythmic myoclonic spasms in dogs.", "content": "Rhythmic myoclonic spasms in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988180"}
{"pmid": "20988182", "title": "Acute salt poisoning in poultry.", "content": "Acute salt poisoning in poultry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988182"}
{"pmid": "20988183", "title": "Veterinary practice, present and future.", "content": "Veterinary practice, present and future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988183"}
{"pmid": "20988181", "title": "A field trial of D.D.T. and gamexane (666) in the control of sheep myiasis.", "content": "A field trial of D.D.T. and gamexane (666) in the control of sheep myiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988181"}
{"pmid": "20988184", "title": "The diagnosis of onchocerciasis.", "content": "The diagnosis of onchocerciasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988184"}
{"pmid": "20988185", "title": "The diagastricus muscle of the dog.", "content": "The diagastricus muscle of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988185"}
{"pmid": "20988186", "title": "A modified intravenous needle.", "content": "A modified intravenous needle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988186"}
{"pmid": "20988187", "title": "The cercaria of Apophallus brevis.", "content": "The cercaria of Apophallus brevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988187"}
{"pmid": "20988189", "title": "Records and descriptions of South African Thysanoptera.", "content": "Records and descriptions of South African Thysanoptera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988189"}
{"pmid": "20988188", "title": "The taxonomist and his needs.", "content": "The taxonomist and his needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988188"}
{"pmid": "20988190", "title": "Gammexane and DDT in fruit fly baits; a preliminary study.", "content": "Gammexane and DDT in fruit fly baits; a preliminary study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988190"}
{"pmid": "20988191", "title": "Synthesis of fat in locusts.", "content": "Synthesis of fat in locusts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988191"}
{"pmid": "20988192", "title": "Insecticides of plant origin, their sources, possible use and exploitation in South Africa.", "content": "Insecticides of plant origin, their sources, possible use and exploitation in South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988192"}
{"pmid": "20988193", "title": "New records of Acari from Southern Africa and the Belgian Congo.", "content": "New records of Acari from Southern Africa and the Belgian Congo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988193"}
{"pmid": "20988194", "title": "Preliminary laboratory experiments with DDT and 666 as locusticides.", "content": "Preliminary laboratory experiments with DDT and 666 as locusticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988194"}
{"pmid": "20988203", "title": "Dilution medium and survival of the psermatozoa of Arbacia punctulata; effect of the medium on respiration.", "content": "Dilution medium and survival of the psermatozoa of Arbacia punctulata; effect of the medium on respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988203"}
{"pmid": "20988204", "title": "The effects of lithium chloride on the fertilized eggs of Nereis limbata.", "content": "The effects of lithium chloride on the fertilized eggs of Nereis limbata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988204"}
{"pmid": "20988205", "title": "Studies on ciliates of the family Ancistrocomidae Chatton and Lwoff (Order Holotricha, suborder Thigmotricha) Hypocomides mytili Chatton and Lwoff, Hypocomides botulae sp. nov., Hypocomides parva sp. nov., Hypocomides kelliae sp. nov., and Insignicoma venusta gen. nov., sp. nov.", "content": "Studies on ciliates of the family Ancistrocomidae Chatton and Lwoff (Order Holotricha, suborder Thigmotricha) Hypocomides mytili Chatton and Lwoff, Hypocomides botulae sp. nov., Hypocomides parva sp. nov., Hypocomides kelliae sp. nov., and Insignicoma venusta gen. nov., sp. nov.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988205"}
{"pmid": "20988206", "title": "Natural heteroagglutinins in the body fluids and seminal fluids of various invertebrates.", "content": "Natural heteroagglutinins in the body fluids and seminal fluids of various invertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988206"}
{"pmid": "20988207", "title": "Distribution and properties of intracellular alkaline phosphases.", "content": "Distribution and properties of intracellular alkaline phosphases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988207"}
{"pmid": "20988208", "title": "Physiology of insect diapause; the role of the brain in the production and termination of pupal dormancy in the giant silkworm, Platysamia cecropia.", "content": "Physiology of insect diapause; the role of the brain in the production and termination of pupal dormancy in the giant silkworm, Platysamia cecropia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988208"}
{"pmid": "20988195", "title": "Anthropology in the Soviet Union 1945.", "content": "Anthropology in the Soviet Union 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988195"}
{"pmid": "20988209", "title": "Autosomal elimination and preferential segregation in the harlequin lobe of certain Discocephalini (Hemiptera).", "content": "Autosomal elimination and preferential segregation in the harlequin lobe of certain Discocephalini (Hemiptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988209"}
{"pmid": "20988196", "title": "What is the total pattern of our Western civilization? Some preliminary observations.", "content": "What is the total pattern of our Western civilization? Some preliminary observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988196"}
{"pmid": "20988210", "title": "The effect of the adult anterior pituitary hormone on the tadpoles and the immature male frogs of the bullfrog, Rana catesbiana.", "content": "The effect of the adult anterior pituitary hormone on the tadpoles and the immature male frogs of the bullfrog, Rana catesbiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988210"}
{"pmid": "20988211", "title": "A micro-respirometer for single prepupae of Drosophila melanogaster Meigen.", "content": "A micro-respirometer for single prepupae of Drosophila melanogaster Meigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988211"}
{"pmid": "20988197", "title": "Notes on the trepanation of prehistoric crania.", "content": "Notes on the trepanation of prehistoric crania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988197"}
{"pmid": "20988212", "title": "The reactions of isolated parts of Spirostomum.", "content": "The reactions of isolated parts of Spirostomum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988212"}
{"pmid": "20988213", "title": "Fertilizing capacity of spermatozoa following cold treatment of the scrotal testes of rabbits.", "content": "Fertilizing capacity of spermatozoa following cold treatment of the scrotal testes of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988213"}
{"pmid": "20988214", "title": "Differentiation of ectoderm implanted into the primordium of the limb bud in the amphibian embryo and its influence upon the limb.", "content": "Differentiation of ectoderm implanted into the primordium of the limb bud in the amphibian embryo and its influence upon the limb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988214"}
{"pmid": "20988215", "title": "Peripheral nerve and regeneration in Crustacea.", "content": "Peripheral nerve and regeneration in Crustacea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988215"}
{"pmid": "20988216", "title": "A critical study of techniques for determining the cytological position of alkaline phosphatase.", "content": "A critical study of techniques for determining the cytological position of alkaline phosphatase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988216"}
{"pmid": "20988217", "title": "The growth of brown trout (Salmo trutta Linn.); factors influencing the growth of trout fry.", "content": "The growth of brown trout (Salmo trutta Linn.); factors influencing the growth of trout fry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988217"}
{"pmid": "20988218", "title": "The growth of brown trout (Salmo trutta Linn.); the growth of two-year-old trout at a constant temperature of 11.5 degrees C.", "content": "The growth of brown trout (Salmo trutta Linn.); the growth of two-year-old trout at a constant temperature of 11.5 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988218"}
{"pmid": "20988219", "title": "The growth of brown trout (Salmo trutta Linn.); the effect of temperature on the growth of two-year-old trout.", "content": "The growth of brown trout (Salmo trutta Linn.); the effect of temperature on the growth of two-year-old trout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988219"}
{"pmid": "20988220", "title": "The dietetics of the clothes moth, Tineola bisselliella Hum.", "content": "The dietetics of the clothes moth, Tineola bisselliella Hum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988220"}
{"pmid": "20988221", "title": "The dietetics of the caterpillars of three Ephestia species, E. kuehniella, E. elutella, and E. cautella, and of a closely related species, Plodia interpunctella.", "content": "The dietetics of the caterpillars of three Ephestia species, E. kuehniella, E. elutella, and E. cautella, and of a closely related species, Plodia interpunctella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988221"}
{"pmid": "20988222", "title": "Linoleic acid, vitamin E and other fat-soluble substances in the nutrition of certain insects, Ephestia kuehniella, E. elutella, E. cautella and Plodia interpunctella (Lep.).", "content": "Linoleic acid, vitamin E and other fat-soluble substances in the nutrition of certain insects, Ephestia kuehniella, E. elutella, E. cautella and Plodia interpunctella (Lep.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988222"}
{"pmid": "20988223", "title": "Volatile acid in the digesta of ruminants and other animals.", "content": "Volatile acid in the digesta of ruminants and other animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988223"}
{"pmid": "20988224", "title": "The influence of peripheral connexion on the diameter of regenerating nerve fibres.", "content": "The influence of peripheral connexion on the diameter of regenerating nerve fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988224"}
{"pmid": "20988225", "title": "Studies on temperature regulation; Amphibia and reptiles.", "content": "Studies on temperature regulation; Amphibia and reptiles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988225"}
{"pmid": "20988226", "title": "The development of the rat eye in graft.", "content": "The development of the rat eye in graft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988226"}
{"pmid": "20988198", "title": "Anthropology during the war; Palestine.", "content": "Anthropology during the war; Palestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988198"}
{"pmid": "20988227", "title": "Control of sex and sex-limited polymorphism in the hymenoptera.", "content": "Control of sex and sex-limited polymorphism in the hymenoptera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988227"}
{"pmid": "20988229", "title": "Actinomyces septicus from human endocarditis.", "content": "Actinomyces septicus from human endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988229"}
{"pmid": "20988230", "title": "Clinical arrest of endocardial actinomycosis after 44 million units of penicillin.", "content": "Clinical arrest of endocardial actinomycosis after 44 million units of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988230"}
{"pmid": "20988231", "title": "The electrocardiographic effects of injury at the endocardial surface of the left ventricle.", "content": "The electrocardiographic effects of injury at the endocardial surface of the left ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988231"}
{"pmid": "20988232", "title": "Electrocardiographic changes in acute glomerulonephritis.", "content": "Electrocardiographic changes in acute glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988232"}
{"pmid": "20988233", "title": "Is there a vagal pulmonocoronary reflex in pulmonary embolism?", "content": "Is there a vagal pulmonocoronary reflex in pulmonary embolism?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988233"}
{"pmid": "20988234", "title": "Unstable T waves in leads II and III in persons with neurocirculatory asthenia.", "content": "Unstable T waves in leads II and III in persons with neurocirculatory asthenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988234"}
{"pmid": "20988235", "title": "A method for the orthodiagraphic measurement of the transverse diameter of the heart by means of the simple fluoroscope.", "content": "A method for the orthodiagraphic measurement of the transverse diameter of the heart by means of the simple fluoroscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988235"}
{"pmid": "20988236", "title": "The effect of splanchnic resection on the peripheral blood flow and rectal and skin temperatures in hypertension.", "content": "The effect of splanchnic resection on the peripheral blood flow and rectal and skin temperatures in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988236"}
{"pmid": "20988237", "title": "Myocardial complications of cutaneous diphtheria.", "content": "Myocardial complications of cutaneous diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988237"}
{"pmid": "20988238", "title": "The presence and pathogenesis of endocardial and subendocardial degeneration, mural thrombi, and thromboses of the thebesian veins in cardiac failure from causes other than myocardial infarction.", "content": "The presence and pathogenesis of endocardial and subendocardial degeneration, mural thrombi, and thromboses of the thebesian veins in cardiac failure from causes other than myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988238"}
{"pmid": "20988239", "title": "Ventricular fibrillation, with special reference to the Morgagni-Adams-Stokes syndrome; report of an unusual case.", "content": "Ventricular fibrillation, with special reference to the Morgagni-Adams-Stokes syndrome; report of an unusual case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988239"}
{"pmid": "20988240", "title": "Fatal coronary failure without infarction; report of a case.", "content": "Fatal coronary failure without infarction; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988240"}
{"pmid": "20988241", "title": "The Wolff-Parkinson-White syndrome in association with congenital heart disease: coarctation of the aorta; report of a case.", "content": "The Wolff-Parkinson-White syndrome in association with congenital heart disease: coarctation of the aorta; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988241"}
{"pmid": "20988242", "title": "A case report of similar symptoms produced by hyperactive carotid sinus reflex, angina pectoris, and myocardial infarction.", "content": "A case report of similar symptoms produced by hyperactive carotid sinus reflex, angina pectoris, and myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988242"}
{"pmid": "20988243", "title": "The long-range care in cases of myocardial infarction and angina pectoris.", "content": "The long-range care in cases of myocardial infarction and angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988243"}
{"pmid": "20988244", "title": "Horse brain thromboplastin; stabilization of activity of suspensions.", "content": "Horse brain thromboplastin; stabilization of activity of suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988244"}
{"pmid": "20988245", "title": "Horse brain thromboplastin; stabilization of activity of dried brain preparations.", "content": "Horse brain thromboplastin; stabilization of activity of dried brain preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988245"}
{"pmid": "20988246", "title": "Sodium-retaining substances of the adrenal.", "content": "Sodium-retaining substances of the adrenal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988246"}
{"pmid": "20988247", "title": "Physico-chemical aspects of the action of anion exchange resins in biochemical systems.", "content": "Physico-chemical aspects of the action of anion exchange resins in biochemical systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988247"}
{"pmid": "20988248", "title": "Partial acid hydrolysates of proteins; intravenous use of high levels of fibrin and casein hydrolysates in hypoproteinemic dogs.", "content": "Partial acid hydrolysates of proteins; intravenous use of high levels of fibrin and casein hydrolysates in hypoproteinemic dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988248"}
{"pmid": "20988249", "title": "Certain factors affecting vitamin C content of bean sprouts.", "content": "Certain factors affecting vitamin C content of bean sprouts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988249"}
{"pmid": "20988250", "title": "The structure of the water insoluble pigment of the bark of Sangre de Drago.", "content": "The structure of the water insoluble pigment of the bark of Sangre de Drago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988250"}
{"pmid": "20988251", "title": "Effect of alkaloids on acetylcholine synthesis.", "content": "Effect of alkaloids on acetylcholine synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988251"}
{"pmid": "20988252", "title": "The distribution and comparative content of certain B-complex vitamins in chicken muscles.", "content": "The distribution and comparative content of certain B-complex vitamins in chicken muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988252"}
{"pmid": "20988253", "title": "Biological inactivity of zeta-carotene.", "content": "Biological inactivity of zeta-carotene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988253"}
{"pmid": "20988254", "title": "Some properties of a flour proteinase.", "content": "Some properties of a flour proteinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988254"}
{"pmid": "20988255", "title": "A note on the amino acids of cataractous and sclerosed human lenses.", "content": "A note on the amino acids of cataractous and sclerosed human lenses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988255"}
{"pmid": "20988256", "title": "Electrophoretic analysis of bovine plasma and serum.", "content": "Electrophoretic analysis of bovine plasma and serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988256"}
{"pmid": "20988257", "title": "lambda-Galacturonic acid from delta-galactose.", "content": "lambda-Galacturonic acid from delta-galactose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988257"}
{"pmid": "20988258", "title": "The effect of baking and toasting on the nutritional value of proteins.", "content": "The effect of baking and toasting on the nutritional value of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988258"}
{"pmid": "20988259", "title": "The reaction of mustard gas with proteins; the nutritional value of casein reacted with mustard gas.", "content": "The reaction of mustard gas with proteins; the nutritional value of casein reacted with mustard gas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988259"}
{"pmid": "20988260", "title": "The reaction of mustard gas with proteins; biological assay of amino acids affected.", "content": "The reaction of mustard gas with proteins; biological assay of amino acids affected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988260"}
{"pmid": "20988261", "title": "On the mechanism of the catalase inhibition by anions.", "content": "On the mechanism of the catalase inhibition by anions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988261"}
{"pmid": "20988291", "title": "Chemical investigations of the insecticide DDT and its analogues.", "content": "Chemical investigations of the insecticide DDT and its analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988291"}
{"pmid": "20988293", "title": "Synthetic antimalarials.", "content": "Synthetic antimalarials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988293"}
{"pmid": "20988292", "title": "Chemical investigations of the insecticide DDT and its analogues; symmetrical analogues.", "content": "Chemical investigations of the insecticide DDT and its analogues; symmetrical analogues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988292"}
{"pmid": "20988295", "title": "Synthetic antimalarials; some derivatives of mono- and di-alkylpyrimidines.", "content": "Synthetic antimalarials; some derivatives of mono- and di-alkylpyrimidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988295"}
{"pmid": "20988294", "title": "Synthetic antimalarials; 2-substituted-anilino-4-aminoalkylamino-6-methylpyrimidines.", "content": "Synthetic antimalarials; 2-substituted-anilino-4-aminoalkylamino-6-methylpyrimidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988294"}
{"pmid": "20988296", "title": "Synthetic antimalarials; 2-phenylguanidino-4-aminoalkylamino-6-methylpyrimidines.", "content": "Synthetic antimalarials; 2-phenylguanidino-4-aminoalkylamino-6-methylpyrimidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988296"}
{"pmid": "20988297", "title": "Synthetic antimalarials; 2-naphthylamino-4-aminoalkylamino-6-methylpyrimidines.", "content": "Synthetic antimalarials; 2-naphthylamino-4-aminoalkylamino-6-methylpyrimidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988297"}
{"pmid": "20988298", "title": "Synthetic antimalarials; some 4-arylamino-2-aminoalkyl-amino-6-methylpyrimidines.", "content": "Synthetic antimalarials; some 4-arylamino-2-aminoalkyl-amino-6-methylpyrimidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988298"}
{"pmid": "20988299", "title": "Synthetic antimalarials; 2-arylamino-4-dialkyl-aminoalkylaminopyrimidines; variation of substituents in the 5- and the 6-position.", "content": "Synthetic antimalarials; 2-arylamino-4-dialkyl-aminoalkylaminopyrimidines; variation of substituents in the 5- and the 6-position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988299"}
{"pmid": "20988300", "title": "The anhydrides of polyhydric alcohols; derivatives of 1:2-5:6-dianhydro mannitol.", "content": "The anhydrides of polyhydric alcohols; derivatives of 1:2-5:6-dianhydro mannitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988300"}
{"pmid": "20988301", "title": "The anhydrides of polyhydric alcohols; derivatives of 5:6-anhydro mannitol and sorbitol.", "content": "The anhydrides of polyhydric alcohols; derivatives of 5:6-anhydro mannitol and sorbitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988301"}
{"pmid": "20988302", "title": "The anhydrides of polyhydric alcohols; the constitution of dianhydro sorbitol.", "content": "The anhydrides of polyhydric alcohols; the constitution of dianhydro sorbitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988302"}
{"pmid": "20988304", "title": "The determination of active hydrogen.", "content": "The determination of active hydrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988304"}
{"pmid": "20988303", "title": "The anhydrides of polyhydric alcohols; 2:5-diamino 1:4-3: 6-dianhydro mannitol and sorbitol and their sulphanilamide derivatives.", "content": "The anhydrides of polyhydric alcohols; 2:5-diamino 1:4-3: 6-dianhydro mannitol and sorbitol and their sulphanilamide derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988303"}
{"pmid": "20988305", "title": "Some recent developments in the chemistry of free radicals.", "content": "Some recent developments in the chemistry of free radicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988305"}
{"pmid": "20988310", "title": "Notes on root canal therapy.", "content": "Notes on root canal therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988310"}
{"pmid": "20988311", "title": "Medical and dental relationship in a maxillofacial team.", "content": "Medical and dental relationship in a maxillofacial team.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988311"}
{"pmid": "20988312", "title": "Personality and oral disease.", "content": "Personality and oral disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988312"}
{"pmid": "20988314", "title": "A maxillary fistula of unusual origin.", "content": "A maxillary fistula of unusual origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988314"}
{"pmid": "20988313", "title": "The possibilities of root canal therapy.", "content": "The possibilities of root canal therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988313"}
{"pmid": "20988315", "title": "Notes on three cases of specific infections of the hand in dental surgeons.", "content": "Notes on three cases of specific infections of the hand in dental surgeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988315"}
{"pmid": "20988316", "title": "An appliance for the expansion of the eye socket.", "content": "An appliance for the expansion of the eye socket.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988316"}
{"pmid": "20988317", "title": "A test of the keeping quality of a penicillin cream.", "content": "A test of the keeping quality of a penicillin cream.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988317"}
{"pmid": "20988306", "title": "Cancer; dietary fat in tumor formation.", "content": "Cancer; dietary fat in tumor formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988306"}
{"pmid": "20988319", "title": "The equalization of pressure in impression taking.", "content": "The equalization of pressure in impression taking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988319"}
{"pmid": "20988318", "title": "Pressure on lingual nerve by impacted third molar.", "content": "Pressure on lingual nerve by impacted third molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988318"}
{"pmid": "20988320", "title": "New patterns in dental practice; system and order.", "content": "New patterns in dental practice; system and order.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988320"}
{"pmid": "20988321", "title": "Lymphatics of the dental region.", "content": "Lymphatics of the dental region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988321"}
{"pmid": "20988309", "title": "Advances in the knowledge of vitamins K1 and K2.", "content": "Advances in the knowledge of vitamins K1 and K2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988309"}
{"pmid": "20988307", "title": "The Kresge-Hooker Scientific Library; a milestone in chemical progress.", "content": "The Kresge-Hooker Scientific Library; a milestone in chemical progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988307"}
{"pmid": "20988322", "title": "General introduction to histological technique; a simplified account of microscopic slide preparation.", "content": "General introduction to histological technique; a simplified account of microscopic slide preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988322"}
{"pmid": "20988308", "title": "Advances in the field of pharmaceuticals and medicinals, 1945.", "content": "Advances in the field of pharmaceuticals and medicinals, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988308"}
{"pmid": "20988324", "title": "The role of third molars in the development of periodontoclasia.", "content": "The role of third molars in the development of periodontoclasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988324"}
{"pmid": "20988323", "title": "Periodontal disease and habits; the effects and treatment of several habits detrimental to the periodontium.", "content": "Periodontal disease and habits; the effects and treatment of several habits detrimental to the periodontium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988323"}
{"pmid": "20988325", "title": "Easy method of recovering cured dentures.", "content": "Easy method of recovering cured dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988325"}
{"pmid": "20988326", "title": "Simple method for securing centric jaw relationship.", "content": "Simple method for securing centric jaw relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988326"}
{"pmid": "20988327", "title": "Time-saving full denture technic; with maximum chair time of three hours.", "content": "Time-saving full denture technic; with maximum chair time of three hours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988327"}
{"pmid": "20988328", "title": "Gold-reinforced acrylic resin fixed bridges.", "content": "Gold-reinforced acrylic resin fixed bridges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988328"}
{"pmid": "20988329", "title": "95 PERCENT use acrylic resin as denture base material.", "content": "95 PERCENT use acrylic resin as denture base material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988329"}
{"pmid": "20988330", "title": "Some points of special interest to general practitioners in the diagnosis of dental malocclusions.", "content": "Some points of special interest to general practitioners in the diagnosis of dental malocclusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988330"}
{"pmid": "20988331", "title": "Sculpture in orthodontics.", "content": "Sculpture in orthodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988331"}
{"pmid": "20988332", "title": "Full lower impression technic.", "content": "Full lower impression technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988332"}
{"pmid": "20988333", "title": "Findings in the roentgenograms of edentulous patients.", "content": "Findings in the roentgenograms of edentulous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988333"}
{"pmid": "20988335", "title": "Postextraction implantation of crystalline penicillin sodium.", "content": "Postextraction implantation of crystalline penicillin sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988335"}
{"pmid": "20988334", "title": "Fibro-osteoma, cyst and impacted third molar of the maxilla; report of case.", "content": "Fibro-osteoma, cyst and impacted third molar of the maxilla; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988334"}
{"pmid": "20988337", "title": "Marion Sims and the Dental Journal; first publication by the father of gynecology in Chapin A. Harris' magazine.", "content": "Marion Sims and the Dental Journal; first publication by the father of gynecology in Chapin A. Harris' magazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988337"}
{"pmid": "20988336", "title": "Oral conditions in experimental vitamin C and B deficiency.", "content": "Oral conditions in experimental vitamin C and B deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988336"}
{"pmid": "20988338", "title": "Past, present and proposed federal health legislation.", "content": "Past, present and proposed federal health legislation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988338"}
{"pmid": "20988339", "title": "STATUS of dentifrices.", "content": "STATUS of dentifrices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988339"}
{"pmid": "20988340", "title": "Natural gingival colors.", "content": "Natural gingival colors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988340"}
{"pmid": "20988341", "title": "Removal of impacted right mandibular second and third molars; report of case.", "content": "Removal of impacted right mandibular second and third molars; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988341"}
{"pmid": "20988342", "title": "Proposed nationwide fluorine survey.", "content": "Proposed nationwide fluorine survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988342"}
{"pmid": "20988343", "title": "The question of office biopsy.", "content": "The question of office biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988343"}
{"pmid": "20988344", "title": "Dental status of 71015 naval personnel at first examination in 1942; age and regional distribution of persons with specific type dental defects.", "content": "Dental status of 71015 naval personnel at first examination in 1942; age and regional distribution of persons with specific type dental defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988344"}
{"pmid": "20988345", "title": "Clinical and bacteriological studies of the use of a fluoride dentifrice.", "content": "Clinical and bacteriological studies of the use of a fluoride dentifrice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988345"}
{"pmid": "20988348", "title": "The appositional life span of the enamel and dentin-forming cells; human deciduous teeth and first permanent molars; introduction.", "content": "The appositional life span of the enamel and dentin-forming cells; human deciduous teeth and first permanent molars; introduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988348"}
{"pmid": "20988346", "title": "Decay of the deciduous teeth of Formosa Chinese; an analytical summary and interpretation of certain statistics published by Maruyama.", "content": "Decay of the deciduous teeth of Formosa Chinese; an analytical summary and interpretation of certain statistics published by Maruyama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988346"}
{"pmid": "20988347", "title": "Hydrolyzed saliva as a source of nutrients essential for the production of acid by an oral strain of Lactobacillus acidophilus.", "content": "Hydrolyzed saliva as a source of nutrients essential for the production of acid by an oral strain of Lactobacillus acidophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988347"}
{"pmid": "20988349", "title": "The relationship between physiologic pigmentation in the oral and outaneous tissues of the Negro.", "content": "The relationship between physiologic pigmentation in the oral and outaneous tissues of the Negro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988349"}
{"pmid": "20988350", "title": "Preliminary observations of the enamel of human and guinea pig teeth using the electron microscope.", "content": "Preliminary observations of the enamel of human and guinea pig teeth using the electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988350"}
{"pmid": "20988351", "title": "Bone growth in paralyzed limbs.", "content": "Bone growth in paralyzed limbs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988351"}
{"pmid": "20988352", "title": "The growth of the mandible.", "content": "The growth of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988352"}
{"pmid": "20988353", "title": "Linear casting shrinkage of gold and its alloys.", "content": "Linear casting shrinkage of gold and its alloys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988353"}
{"pmid": "20988354", "title": "Effect of time and temperature on polymerizatien of acrylic resins.", "content": "Effect of time and temperature on polymerizatien of acrylic resins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988354"}
{"pmid": "20988355", "title": "Effect of various agents on enamel solubility.", "content": "Effect of various agents on enamel solubility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988355"}
{"pmid": "20988356", "title": "Serial course of dental caries in children receiving recurrent dental care.", "content": "Serial course of dental caries in children receiving recurrent dental care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988356"}
{"pmid": "20988357", "title": "Agglutination studies of the smaller oral Treponemata, Borrelia vincentii and cultured strains of Treponema pallidum.", "content": "Agglutination studies of the smaller oral Treponemata, Borrelia vincentii and cultured strains of Treponema pallidum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988357"}
{"pmid": "20988359", "title": "Various degrees of development of hypercalcified barriers in the dentin.", "content": "Various degrees of development of hypercalcified barriers in the dentin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988359"}
{"pmid": "20988358", "title": "A preliminary report on the bacteriology of the carious lesion in the dentin; a study of the behavior of microorganisms taken from the dentin beneath the unbroken enamel surface.", "content": "A preliminary report on the bacteriology of the carious lesion in the dentin; a study of the behavior of microorganisms taken from the dentin beneath the unbroken enamel surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988358"}
{"pmid": "20988360", "title": "Plaque formation, periodontal disease, and dental caries in Syrian hamsters.", "content": "Plaque formation, periodontal disease, and dental caries in Syrian hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988360"}
{"pmid": "20988361", "title": "Variations in counts of lactobacilli made on single specimens of saliva.", "content": "Variations in counts of lactobacilli made on single specimens of saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988361"}
{"pmid": "20988362", "title": "Nerve fiber degeneration following tooth removal.", "content": "Nerve fiber degeneration following tooth removal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988362"}
{"pmid": "20988363", "title": "The formation of secondary dentin.", "content": "The formation of secondary dentin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988363"}
{"pmid": "20988364", "title": "The capacity of periodontal vessels on pressure and tension sides of teeth moved by orthodontic appliances.", "content": "The capacity of periodontal vessels on pressure and tension sides of teeth moved by orthodontic appliances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988364"}
{"pmid": "20988365", "title": "Chemical studies in periodental disease; the rate of putrefaction of salivary proteins as an index of periodontal disease.", "content": "Chemical studies in periodental disease; the rate of putrefaction of salivary proteins as an index of periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988365"}
{"pmid": "20988366", "title": "Exposed dental pulp as a possible portal of entry for the polio virus.", "content": "Exposed dental pulp as a possible portal of entry for the polio virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988366"}
{"pmid": "20988367", "title": "Changes in the incisors of hypophysectomized female rats after different postoperative periods.", "content": "Changes in the incisors of hypophysectomized female rats after different postoperative periods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988367"}
{"pmid": "20988369", "title": "Growth and transformation of the mandibular joint in the rat; normal female rats.", "content": "Growth and transformation of the mandibular joint in the rat; normal female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988369"}
{"pmid": "20988368", "title": "Growth and transformation of the mandibular joint in the rat; the effect of growth hormone and thyroxin injections in hypophysectiomized rats.", "content": "Growth and transformation of the mandibular joint in the rat; the effect of growth hormone and thyroxin injections in hypophysectiomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988368"}
{"pmid": "20988370", "title": "Penicillin in the treatment of infections of the face and jaws.", "content": "Penicillin in the treatment of infections of the face and jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988370"}
{"pmid": "20988371", "title": "Dental changes of rats and hamsters in vitamin E deficiency.", "content": "Dental changes of rats and hamsters in vitamin E deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988371"}
{"pmid": "20988372", "title": "Blood studies in periodontoclasia.", "content": "Blood studies in periodontoclasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988372"}
{"pmid": "20988373", "title": "Some observations on the use of streptothrycin in protecting chicken embroys against infection by salivary bacteria.", "content": "Some observations on the use of streptothrycin in protecting chicken embroys against infection by salivary bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988373"}
{"pmid": "20988374", "title": "Experimental amelectomy.", "content": "Experimental amelectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988374"}
{"pmid": "20988375", "title": "Effects of variation in the mercury-alloy ratio upon the amalgam filling.", "content": "Effects of variation in the mercury-alloy ratio upon the amalgam filling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988375"}
{"pmid": "20988376", "title": "Studies on density of castings as related to the position in the ring.", "content": "Studies on density of castings as related to the position in the ring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988376"}
{"pmid": "20988379", "title": "Surgical treatment of prognathism.", "content": "Surgical treatment of prognathism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988379"}
{"pmid": "20988378", "title": "Eosinophilic granuloma.", "content": "Eosinophilic granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988378"}
{"pmid": "20988377", "title": "Effect of acute pantothenic acid deficiency on the tibia of young rats.", "content": "Effect of acute pantothenic acid deficiency on the tibia of young rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988377"}
{"pmid": "20988380", "title": "Drugs and prescription writing in dentistry.", "content": "Drugs and prescription writing in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988380"}
{"pmid": "20988381", "title": "The treatment of pyorrhoea.", "content": "The treatment of pyorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988381"}
{"pmid": "20988383", "title": "BASIC FEE schedule of Veterans Administration, effective May 25, 1946.", "content": "BASIC FEE schedule of Veterans Administration, effective May 25, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988383"}
{"pmid": "20988382", "title": "The occupational hazards in dental practice.", "content": "The occupational hazards in dental practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988382"}
{"pmid": "20988394", "title": "The vitamin B complex.", "content": "The vitamin B complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988394"}
{"pmid": "20988395", "title": "The vitamin B complex; introductory survey.", "content": "The vitamin B complex; introductory survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988395"}
{"pmid": "20988396", "title": "Role of members of the vitamin B complex in enzyme systems.", "content": "Role of members of the vitamin B complex in enzyme systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988396"}
{"pmid": "20988397", "title": "Some recently characterized members of the vitamin B2 complex.", "content": "Some recently characterized members of the vitamin B2 complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988397"}
{"pmid": "20988398", "title": "Growth factors and growth inhibitors for micro-organisms.", "content": "Growth factors and growth inhibitors for micro-organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988398"}
{"pmid": "20988399", "title": "Fermentation and human nutrition.", "content": "Fermentation and human nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988399"}
{"pmid": "20988400", "title": "The vitamin B2 complex and anaemia.", "content": "The vitamin B2 complex and anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988400"}
{"pmid": "20988401", "title": "Some aspects of the waste problem; cooking and plate waste.", "content": "Some aspects of the waste problem; cooking and plate waste.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988401"}
{"pmid": "20988393", "title": "Lupus erythematosis; treatment with penicillin.", "content": "Lupus erythematosis; treatment with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988393"}
{"pmid": "20988402", "title": "Loss of nutrients in cooking.", "content": "Loss of nutrients in cooking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988402"}
{"pmid": "20988404", "title": "Losses of nutrients in the conservation of farm produce and of animal feeding stuffs.", "content": "Losses of nutrients in the conservation of farm produce and of animal feeding stuffs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988404"}
{"pmid": "20988391", "title": "Prospect and retrospect.", "content": "Prospect and retrospect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988391"}
{"pmid": "20988403", "title": "The loss of ascorbic acid in food.", "content": "The loss of ascorbic acid in food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988403"}
{"pmid": "20988406", "title": "Observations on the chemical cytology of the thyroid gland at different functional stages.", "content": "Observations on the chemical cytology of the thyroid gland at different functional stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988406"}
{"pmid": "20988392", "title": "Erythema gyratum perstans (Colcott Fox); a case report, with discussion on relations with erythema centrifugum annulare (Darier) and dermatitis herpetiformis.", "content": "Erythema gyratum perstans (Colcott Fox); a case report, with discussion on relations with erythema centrifugum annulare (Darier) and dermatitis herpetiformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988392"}
{"pmid": "20988405", "title": "The effect of thyroxin and dinitrophenol on the thermal responses to cold.", "content": "The effect of thyroxin and dinitrophenol on the thermal responses to cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988405"}
{"pmid": "20988407", "title": "The role of the adrenals in the production of nephrosclerosis by anterior pituitary preparations.", "content": "The role of the adrenals in the production of nephrosclerosis by anterior pituitary preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988407"}
{"pmid": "20988408", "title": "Effect of vitamin B complex deficiency, controlled inanition and methionine on inactivation of estrogen by the liver.", "content": "Effect of vitamin B complex deficiency, controlled inanition and methionine on inactivation of estrogen by the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988408"}
{"pmid": "20988409", "title": "The influence of selected goitrogenic compounds on the thyroid gland of the chick.", "content": "The influence of selected goitrogenic compounds on the thyroid gland of the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988409"}
{"pmid": "20988410", "title": "Influence of adrenal cortical steroids upon the blood pressure and the rate of progression of experimental nephritis in rats.", "content": "Influence of adrenal cortical steroids upon the blood pressure and the rate of progression of experimental nephritis in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988410"}
{"pmid": "20988411", "title": "Hyperplasia of the thyroid gland of rhesus monkeys after thiouracil treatment.", "content": "Hyperplasia of the thyroid gland of rhesus monkeys after thiouracil treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988411"}
{"pmid": "20988412", "title": "Some effects of the administration of thiouracil to monkeys.", "content": "Some effects of the administration of thiouracil to monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988412"}
{"pmid": "20988414", "title": "Diethylstilbestrol in aqueous suspension.", "content": "Diethylstilbestrol in aqueous suspension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988414"}
{"pmid": "20988413", "title": "Therapy with aqueous suspensions of testosterone.", "content": "Therapy with aqueous suspensions of testosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988413"}
{"pmid": "20988416", "title": "A case of primary amenorrhea.", "content": "A case of primary amenorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988416"}
{"pmid": "20988415", "title": "Testosterone pellet implantation.", "content": "Testosterone pellet implantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988415"}
{"pmid": "20988417", "title": "The Xenopus test in tumour of the testis.", "content": "The Xenopus test in tumour of the testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988417"}
{"pmid": "20988418", "title": "A cytological study of some triploid onion plants.", "content": "A cytological study of some triploid onion plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988418"}
{"pmid": "20988419", "title": "Mutations of mink under domestication.", "content": "Mutations of mink under domestication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988419"}
{"pmid": "20988420", "title": "Genetics of sesame; open sesame and mottled leaf.", "content": "Genetics of sesame; open sesame and mottled leaf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988420"}
{"pmid": "20988421", "title": "Hereditary Legg-Calve-Perthes' disease.", "content": "Hereditary Legg-Calve-Perthes' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988421"}
{"pmid": "20988457", "title": "MATERNAL mortality reports.", "content": "MATERNAL mortality reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988457"}
{"pmid": "20988468", "title": "Malaria.", "content": "Malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988468"}
{"pmid": "20988469", "title": "Sodium pentothal; its properties and uses.", "content": "Sodium pentothal; its properties and uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988469"}
{"pmid": "20988470", "title": "Butyric acid and duodenal ulcer.", "content": "Butyric acid and duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988470"}
{"pmid": "20988471", "title": "The sulfonamides and penicillin as immunizing agents.", "content": "The sulfonamides and penicillin as immunizing agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988471"}
{"pmid": "20988472", "title": "The future of homeopathy.", "content": "The future of homeopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988472"}
{"pmid": "20988474", "title": "British hospitals and medical research.", "content": "British hospitals and medical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988474"}
{"pmid": "20988473", "title": "Post-war trends in convalescence.", "content": "Post-war trends in convalescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988473"}
{"pmid": "20988475", "title": "CIVILIAN hospitals and the war.", "content": "CIVILIAN hospitals and the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988475"}
{"pmid": "20988476", "title": "Lighting installations in the hospital.", "content": "Lighting installations in the hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988476"}
{"pmid": "20988477", "title": "Hospital planning; general service departments.", "content": "Hospital planning; general service departments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988477"}
{"pmid": "20988478", "title": "OUT-PATIENT appointments system.", "content": "OUT-PATIENT appointments system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988478"}
{"pmid": "20988479", "title": "The hospital laundry.", "content": "The hospital laundry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988479"}
{"pmid": "20988480", "title": "Psychiatry is good business in the general hospital.", "content": "Psychiatry is good business in the general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988480"}
{"pmid": "20988481", "title": "Medical illustration.", "content": "Medical illustration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988481"}
{"pmid": "20988482", "title": "Problems of the heart.", "content": "Problems of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988482"}
{"pmid": "20988483", "title": "Chemical constitution and pharmacological action.", "content": "Chemical constitution and pharmacological action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988483"}
{"pmid": "20988484", "title": "Reforms are called for in feeding the mentally ill.", "content": "Reforms are called for in feeding the mentally ill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988484"}
{"pmid": "20988486", "title": "Medical staff organization and procedure.", "content": "Medical staff organization and procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988486"}
{"pmid": "20988485", "title": "The record library as a service department.", "content": "The record library as a service department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988485"}
{"pmid": "20988491", "title": "Shigella sp. Wakefield and its relations to Shigella sp. Sachs Q454.", "content": "Shigella sp. Wakefield and its relations to Shigella sp. Sachs Q454.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988491"}
{"pmid": "20988492", "title": "A specific antigen recovered from tissue infected with M. paratuberculosis (johne's bacillus); studies on the nature of the antigen and on methods for demasking it.", "content": "A specific antigen recovered from tissue infected with M. paratuberculosis (johne's bacillus); studies on the nature of the antigen and on methods for demasking it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988492"}
{"pmid": "20988493", "title": "Differentiation of some disorders of the lymphatic system by leukoagglutination.", "content": "Differentiation of some disorders of the lymphatic system by leukoagglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988493"}
{"pmid": "20988494", "title": "The antigenic properties of fibrin films and foams prepared from human and from bovine blood plasma.", "content": "The antigenic properties of fibrin films and foams prepared from human and from bovine blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988494"}
{"pmid": "20988495", "title": "Studies on the chemotherapy of viruses in the psittacosis-lymphogranuloma venereum group; effect of certain chemotherapeutic agents on the growth of psittacosis virus (6BC strain) in tissues cultures and eggs.", "content": "Studies on the chemotherapy of viruses in the psittacosis-lymphogranuloma venereum group; effect of certain chemotherapeutic agents on the growth of psittacosis virus (6BC strain) in tissues cultures and eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988495"}
{"pmid": "20988496", "title": "Sedimentation of poliomyelitis virus in the Sharples centrifuge.", "content": "Sedimentation of poliomyelitis virus in the Sharples centrifuge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988496"}
{"pmid": "20988497", "title": "Infection of rats with the virus of influenza.", "content": "Infection of rats with the virus of influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988497"}
{"pmid": "20988498", "title": "Preliminary standardization of the cardiolipin-lecithin-cholesterol antigen for a microprecipitation test for syphilis.", "content": "Preliminary standardization of the cardiolipin-lecithin-cholesterol antigen for a microprecipitation test for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988498"}
{"pmid": "20988499", "title": "The efficiency of different Sharples centrifuge bowls in the concentration of tobacco mosaic and influenza viruses.", "content": "The efficiency of different Sharples centrifuge bowls in the concentration of tobacco mosaic and influenza viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988499"}
{"pmid": "20988500", "title": "Studies on the physiology of anaphylactic shock; anaphylactic shock in the white rat; experiments in vivo.", "content": "Studies on the physiology of anaphylactic shock; anaphylactic shock in the white rat; experiments in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988500"}
{"pmid": "20988501", "title": "Studies on lymphogranuloma venereum complement-fixing antigens the solubility in ether of an active fraction.", "content": "Studies on lymphogranuloma venereum complement-fixing antigens the solubility in ether of an active fraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988501"}
{"pmid": "20988502", "title": "The measurement of Negro passing.", "content": "The measurement of Negro passing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988502"}
{"pmid": "20988503", "title": "Negro-white relations as reflected in social types.", "content": "Negro-white relations as reflected in social types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988503"}
{"pmid": "20988504", "title": "The measurement of attitudes toward the Japanese in America.", "content": "The measurement of attitudes toward the Japanese in America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988504"}
{"pmid": "20988543", "title": "Discomfort glare and angular distance of glaresource.", "content": "Discomfort glare and angular distance of glaresource.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988543"}
{"pmid": "20988544", "title": "Workmen's compensation for seamen.", "content": "Workmen's compensation for seamen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988544"}
{"pmid": "20988545", "title": "WELFARE provisions for miners in six foreign countries.", "content": "WELFARE provisions for miners in six foreign countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988545"}
{"pmid": "20988546", "title": "Work accidents in Chile.", "content": "Work accidents in Chile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988546"}
{"pmid": "20988547", "title": "Roads to regimentation or pathways to freedom?", "content": "Roads to regimentation or pathways to freedom?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988547"}
{"pmid": "20988548", "title": "Prescription for medical plans.", "content": "Prescription for medical plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988548"}
{"pmid": "20988549", "title": "Studies on malarial parasites; a procedure for preparing concentrates of Plasmodium vivax.", "content": "Studies on malarial parasites; a procedure for preparing concentrates of Plasmodium vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988549"}
{"pmid": "20988552", "title": "The biochemistry of the malaria parasite; the in vitro effects of x-rays upon Plasmodium gallinaceum.", "content": "The biochemistry of the malaria parasite; the in vitro effects of x-rays upon Plasmodium gallinaceum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988552"}
{"pmid": "20988550", "title": "Studies on malarial parasites; some observations regarding the age of the erythrocyte invaded by Plasmodium vivax.", "content": "Studies on malarial parasites; some observations regarding the age of the erythrocyte invaded by Plasmodium vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988550"}
{"pmid": "20988556", "title": "The use of antibiotics, vitamin analogues and other compounds in experimental gas gangrene.", "content": "The use of antibiotics, vitamin analogues and other compounds in experimental gas gangrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988556"}
{"pmid": "20988554", "title": "The instability of the agglutinative reaction in beta hemolytic streptococci of group A.", "content": "The instability of the agglutinative reaction in beta hemolytic streptococci of group A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988554"}
{"pmid": "20988551", "title": "A study of the survival of certain strains of viruses after lyophilization and prolonged storage.", "content": "A study of the survival of certain strains of viruses after lyophilization and prolonged storage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988551"}
{"pmid": "20988555", "title": "Protective effects of bacteria on western equine encephalomyelitis virus.", "content": "Protective effects of bacteria on western equine encephalomyelitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988555"}
{"pmid": "20988559", "title": "The action of clavacin isomer and related compounds on tetanus toxin.", "content": "The action of clavacin isomer and related compounds on tetanus toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988559"}
{"pmid": "20988568", "title": "Bronchoscopy as an aid in the diagnosis and treatment of postoperative pulmonary complications.", "content": "Bronchoscopy as an aid in the diagnosis and treatment of postoperative pulmonary complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988568"}
{"pmid": "20988558", "title": "Photography of airborne particles during bacteriological plating operations.", "content": "Photography of airborne particles during bacteriological plating operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988558"}
{"pmid": "20988553", "title": "Bacteriology of a collection of Shigella strains typed by Weil's method.", "content": "Bacteriology of a collection of Shigella strains typed by Weil's method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988553"}
{"pmid": "20988557", "title": "Functional antigens in helminths.", "content": "Functional antigens in helminths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988557"}
{"pmid": "20988579", "title": "The testing of local anaesthetics.", "content": "The testing of local anaesthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988579"}
{"pmid": "20988580", "title": "Changes in activity of pulmonary receptors in anaesthesia and their influence on respiratory behaviour.", "content": "Changes in activity of pulmonary receptors in anaesthesia and their influence on respiratory behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988580"}
{"pmid": "20988581", "title": "The search for morphine substitutes.", "content": "The search for morphine substitutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988581"}
{"pmid": "20988582", "title": "Synthetic substitutes for atropine.", "content": "Synthetic substitutes for atropine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988582"}
{"pmid": "20988584", "title": "The visual measurement of blood-pressure.", "content": "The visual measurement of blood-pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988584"}
{"pmid": "20988583", "title": "The maintenance of blood-pressure in anaesthesia.", "content": "The maintenance of blood-pressure in anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988583"}
{"pmid": "20988585", "title": "The nature of meningitis following spinal anaesthesia and its prevention.", "content": "The nature of meningitis following spinal anaesthesia and its prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988585"}
{"pmid": "20988586", "title": "Trichlor ethylene as an anaesthetic agent.", "content": "Trichlor ethylene as an anaesthetic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988586"}
{"pmid": "20988587", "title": "Curare.", "content": "Curare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988587"}
{"pmid": "20988588", "title": "Controlled-respiration anaesthesia.", "content": "Controlled-respiration anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988588"}
{"pmid": "20988590", "title": "An outline of the history of anaesthesia, 1846-1900.", "content": "An outline of the history of anaesthesia, 1846-1900.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988590"}
{"pmid": "20988589", "title": "The anaesthetist and the care of the surgical case.", "content": "The anaesthetist and the care of the surgical case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988589"}
{"pmid": "20988591", "title": "The hundredth year of anaesthesia; a short survey of modern anaesthetic practice.", "content": "The hundredth year of anaesthesia; a short survey of modern anaesthetic practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988591"}
{"pmid": "20988592", "title": "The evolution of anesthetic apparatus; a brief pictorial survey.", "content": "The evolution of anesthetic apparatus; a brief pictorial survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988592"}
{"pmid": "20988593", "title": "The first use of chloroform in surgery.", "content": "The first use of chloroform in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988593"}
{"pmid": "20988594", "title": "Popular reactions to the other discovery.", "content": "Popular reactions to the other discovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988594"}
{"pmid": "20988596", "title": "Early surgical anaesthesia in Spain.", "content": "Early surgical anaesthesia in Spain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988596"}
{"pmid": "20988595", "title": "The beginnings of surgical anaesthesia in France; ether and chloroform.", "content": "The beginnings of surgical anaesthesia in France; ether and chloroform.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988595"}
{"pmid": "20988597", "title": "Anaesthesia in Argentina.", "content": "Anaesthesia in Argentina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988597"}
{"pmid": "20988599", "title": "Surgical anaesthesia through mesmerism.", "content": "Surgical anaesthesia through mesmerism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988599"}
{"pmid": "20988598", "title": "Intravenous injection and anaesthesia.", "content": "Intravenous injection and anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988598"}
{"pmid": "20988600", "title": "The medical direction of a series of films on anaesthesia.", "content": "The medical direction of a series of films on anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988600"}
{"pmid": "20988601", "title": "BRITISH Medical Association and the National Health Service Bill.", "content": "BRITISH Medical Association and the National Health Service Bill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988601"}
{"pmid": "20988602", "title": "Application of nutrition to public health; some lessons of the war.", "content": "Application of nutrition to public health; some lessons of the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988602"}
{"pmid": "20988603", "title": "Treatment of chest wounds in forward areas; a review of 100 cases.", "content": "Treatment of chest wounds in forward areas; a review of 100 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988603"}
{"pmid": "20988604", "title": "Myelitis from mumps.", "content": "Myelitis from mumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988604"}
{"pmid": "20988605", "title": "Intestinal obstruction during late pregnancy.", "content": "Intestinal obstruction during late pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988605"}
{"pmid": "20988606", "title": "Traumatic blepharospasm as an isolated symptom.", "content": "Traumatic blepharospasm as an isolated symptom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988606"}
{"pmid": "20988607", "title": "Obstructed labour due to sacral tumour of foetus.", "content": "Obstructed labour due to sacral tumour of foetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988607"}
{"pmid": "20988608", "title": "PROFESSION and the Bill; mass meeting of Surrey practitioners.", "content": "PROFESSION and the Bill; mass meeting of Surrey practitioners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988608"}
{"pmid": "20988609", "title": "Some aspects of chemistry related to medicine.", "content": "Some aspects of chemistry related to medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988609"}
{"pmid": "20988610", "title": "Lumbo-sacral root pain.", "content": "Lumbo-sacral root pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988610"}
{"pmid": "20988611", "title": "Treatment of Sonne III bacillary dysentery and bacillary dysentery (clinical) with phthalyl sulphathiazole.", "content": "Treatment of Sonne III bacillary dysentery and bacillary dysentery (clinical) with phthalyl sulphathiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988611"}
{"pmid": "20988612", "title": "Bacteriology of stomach and duodenum in cases of peptic ulcer and gastric carcinoma.", "content": "Bacteriology of stomach and duodenum in cases of peptic ulcer and gastric carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988612"}
{"pmid": "20988613", "title": "Treatment of branchial cleft cysts by aspiration and injection of pure carbolic acid.", "content": "Treatment of branchial cleft cysts by aspiration and injection of pure carbolic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988613"}
{"pmid": "20988614", "title": "Post-operative mania treated by continuous intravenous pentothal.", "content": "Post-operative mania treated by continuous intravenous pentothal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988614"}
{"pmid": "20988615", "title": "Proteus vulgaris septicaemia treated with penicillin.", "content": "Proteus vulgaris septicaemia treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988615"}
{"pmid": "20988616", "title": "Myiasis, fillan, and the morgellons.", "content": "Myiasis, fillan, and the morgellons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988616"}
{"pmid": "20988617", "title": "Infected clothing.", "content": "Infected clothing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988617"}
{"pmid": "20988619", "title": "A review of present day immunization, practice and procedures.", "content": "A review of present day immunization, practice and procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988619"}
{"pmid": "20988618", "title": "The beginning of institutional medical education in Cleveland.", "content": "The beginning of institutional medical education in Cleveland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988618"}
{"pmid": "20988620", "title": "Some newer developments in diagnostic laboratory procedures.", "content": "Some newer developments in diagnostic laboratory procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988620"}
{"pmid": "20988621", "title": "Injuries of the intestines.", "content": "Injuries of the intestines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988621"}
{"pmid": "20988622", "title": "Arthritis.", "content": "Arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988622"}
{"pmid": "20988623", "title": "Peripheral vascular disorders.", "content": "Peripheral vascular disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988623"}
{"pmid": "20988624", "title": "Electrocardiographic abnormalities in 6,000 cases of rheumatic fever.", "content": "Electrocardiographic abnormalities in 6,000 cases of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988624"}
{"pmid": "20988626", "title": "Poliomyelitis.", "content": "Poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988626"}
{"pmid": "20988625", "title": "Tularemic pneumonia; report of a fatal case.", "content": "Tularemic pneumonia; report of a fatal case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988625"}
{"pmid": "20988627", "title": "Hypertension; some recent advances in our knowledge.", "content": "Hypertension; some recent advances in our knowledge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988627"}
{"pmid": "20988628", "title": "Human plasma, surplus dried; its distribution in California.", "content": "Human plasma, surplus dried; its distribution in California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988628"}
{"pmid": "20988629", "title": "Blast injury of the spine.", "content": "Blast injury of the spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988629"}
{"pmid": "20988631", "title": "The industrial physician in the community health program.", "content": "The industrial physician in the community health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988631"}
{"pmid": "20988630", "title": "Pollinosis in Imperial County, California, and Yuma, Arizona.", "content": "Pollinosis in Imperial County, California, and Yuma, Arizona.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988630"}
{"pmid": "20988632", "title": "LEPROSY in San Francisco.", "content": "LEPROSY in San Francisco.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988632"}
{"pmid": "20988633", "title": "Prognosis in minimal pulmonary tuberculosis.", "content": "Prognosis in minimal pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988633"}
{"pmid": "20988634", "title": "A simple and efficient method of treatment of fractures involving the ankle.", "content": "A simple and efficient method of treatment of fractures involving the ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988634"}
{"pmid": "20988636", "title": "The effect of low protein diet on the structure of the pancreas (preliminary report).", "content": "The effect of low protein diet on the structure of the pancreas (preliminary report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988636"}
{"pmid": "20988635", "title": "The value of lumbar sympathetic procaine block.", "content": "The value of lumbar sympathetic procaine block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988635"}
{"pmid": "20988637", "title": "Infectious mononucleosis.", "content": "Infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988637"}
{"pmid": "20988638", "title": "Treatment of cystine calculi.", "content": "Treatment of cystine calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988638"}
{"pmid": "20988639", "title": "The concurrent use of liver and thiouracil.", "content": "The concurrent use of liver and thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988639"}
{"pmid": "20988640", "title": "Silicones and blood coagulation.", "content": "Silicones and blood coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988640"}
{"pmid": "20988641", "title": "The principles and practice of inguinal herniorrhaphy.", "content": "The principles and practice of inguinal herniorrhaphy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988641"}
{"pmid": "20988642", "title": "Identification of identical strains of staphylococci in food poisoning and other infections by bacteriophage typing.", "content": "Identification of identical strains of staphylococci in food poisoning and other infections by bacteriophage typing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988642"}
{"pmid": "20988644", "title": "The effect of closed plaster treatment on the urinary loss of nitrogen after experimental burning.", "content": "The effect of closed plaster treatment on the urinary loss of nitrogen after experimental burning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988644"}
{"pmid": "20988643", "title": "General anaesthesia for tonsillectomy.", "content": "General anaesthesia for tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988643"}
{"pmid": "20988645", "title": "The relief of pain in labour with demerol.", "content": "The relief of pain in labour with demerol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988645"}
{"pmid": "20988646", "title": "Orthoptic treatment in convergence insufficiency.", "content": "Orthoptic treatment in convergence insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988646"}
{"pmid": "20988647", "title": "Endocarditis due to Brucella abortus.", "content": "Endocarditis due to Brucella abortus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988647"}
{"pmid": "20988648", "title": "Congenital anomaly and fracture of the atlas; two cases.", "content": "Congenital anomaly and fracture of the atlas; two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988648"}
{"pmid": "20988649", "title": "Manic depressive psychosis (manic phase) and electroshock.", "content": "Manic depressive psychosis (manic phase) and electroshock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988649"}
{"pmid": "20988651", "title": "The clinical importance of antigenic differences in human blood.", "content": "The clinical importance of antigenic differences in human blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988651"}
{"pmid": "20988650", "title": "Pleural effusion associated with ovarian tumours (Meigs' syndrome).", "content": "Pleural effusion associated with ovarian tumours (Meigs' syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988650"}
{"pmid": "20988652", "title": "Further experience with the slanted capillary method for Rh typing of red blood cells.", "content": "Further experience with the slanted capillary method for Rh typing of red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988652"}
{"pmid": "20988653", "title": "Indwelling catheter vs. intermittent catheterization.", "content": "Indwelling catheter vs. intermittent catheterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988653"}
{"pmid": "20988658", "title": "Some therapeutic considerations of uncomplicated diabetes.", "content": "Some therapeutic considerations of uncomplicated diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988658"}
{"pmid": "20988659", "title": "The treatment of arthritic and rheumatic conditions.", "content": "The treatment of arthritic and rheumatic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988659"}
{"pmid": "20988654", "title": "Pitfalls in the diagnosis of pulmonary disease.", "content": "Pitfalls in the diagnosis of pulmonary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988654"}
{"pmid": "20988656", "title": "Some obstructive conditions in the upper abdomen in infancy.", "content": "Some obstructive conditions in the upper abdomen in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988656"}
{"pmid": "20988655", "title": "Glaucoma.", "content": "Glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988655"}
{"pmid": "20988670", "title": "Super-microscopes.", "content": "Super-microscopes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988670"}
{"pmid": "20988657", "title": "The post-cholecystectomy syndrome; biliary dyskinesia; biliary dyssynergia.", "content": "The post-cholecystectomy syndrome; biliary dyskinesia; biliary dyssynergia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988657"}
{"pmid": "20988669", "title": "Will atom-splitting revolutionise medicine?", "content": "Will atom-splitting revolutionise medicine?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988669"}
{"pmid": "20988671", "title": "Adrenaline, and some of its uses.", "content": "Adrenaline, and some of its uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988671"}
{"pmid": "20988672", "title": "The social function of the British Medical Association in Kenya.", "content": "The social function of the British Medical Association in Kenya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988672"}
{"pmid": "20988673", "title": "The Nairobi limb-fitting centre.", "content": "The Nairobi limb-fitting centre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988673"}
{"pmid": "20988674", "title": "Pemphigoid eruption following burns.", "content": "Pemphigoid eruption following burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988674"}
{"pmid": "20988675", "title": "The egg of Anopheles squamosus Theobald.", "content": "The egg of Anopheles squamosus Theobald.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988675"}
{"pmid": "20988676", "title": "Perforated gastric ulcer in a Mugishu native.", "content": "Perforated gastric ulcer in a Mugishu native.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988676"}
{"pmid": "20988685", "title": "Total cystectomy in the treatment of bladder tumours.", "content": "Total cystectomy in the treatment of bladder tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988685"}
{"pmid": "20988684", "title": "Transmission of acute infective hepatitis: therapeutic effect on rheumatoid arthritis.", "content": "Transmission of acute infective hepatitis: therapeutic effect on rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988684"}
{"pmid": "20988686", "title": "Copper in gallstones.", "content": "Copper in gallstones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988686"}
{"pmid": "20988687", "title": "Congenital heart disease.", "content": "Congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988687"}
{"pmid": "20988715", "title": "Penicillin therapy compared with sulphonamide therapy in cerebrospinal fever.", "content": "Penicillin therapy compared with sulphonamide therapy in cerebrospinal fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988715"}
{"pmid": "20988717", "title": "A comparative study of saponin broth and bile broth as a blood-culture medium for isolation of enteric group of organisms.", "content": "A comparative study of saponin broth and bile broth as a blood-culture medium for isolation of enteric group of organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988717"}
{"pmid": "20988716", "title": "Enteric fevers in Lahore.", "content": "Enteric fevers in Lahore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988716"}
{"pmid": "20988718", "title": "Proteolysed liver extract in the treatment of tropical macrocytic anaemia.", "content": "Proteolysed liver extract in the treatment of tropical macrocytic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988718"}
{"pmid": "20988719", "title": "Argemone oil.", "content": "Argemone oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988719"}
{"pmid": "20988720", "title": "Plasma cell myelomatosis.", "content": "Plasma cell myelomatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988720"}
{"pmid": "20988721", "title": "Needle biopsy of the liver; technique and diagnostic application.", "content": "Needle biopsy of the liver; technique and diagnostic application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988721"}
{"pmid": "20988722", "title": "A preliminary study of six-hour rat test for the diagnosis of pregnancy.", "content": "A preliminary study of six-hour rat test for the diagnosis of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988722"}
{"pmid": "20988723", "title": "Penicillin in the treatment of carbuncle.", "content": "Penicillin in the treatment of carbuncle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988723"}
{"pmid": "20988724", "title": "Rupture of aneurysm of aorta.", "content": "Rupture of aneurysm of aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988724"}
{"pmid": "20988725", "title": "A Wassermann-positive case of paralytic chorea.", "content": "A Wassermann-positive case of paralytic chorea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988725"}
{"pmid": "20988726", "title": "Enlarged prostate treated with stilboestrol.", "content": "Enlarged prostate treated with stilboestrol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988726"}
{"pmid": "20988727", "title": "A case of ruptured uterus.", "content": "A case of ruptured uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988727"}
{"pmid": "20988728", "title": "THE Rh problem in India.", "content": "THE Rh problem in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988728"}
{"pmid": "20988729", "title": "Some problems of medical and general interest.", "content": "Some problems of medical and general interest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988729"}
{"pmid": "20988730", "title": "The influence of feeding on infant mortality.", "content": "The influence of feeding on infant mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988730"}
{"pmid": "20988731", "title": "The nursing school and public health nursing.", "content": "The nursing school and public health nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988731"}
{"pmid": "20988732", "title": "At the bed-side of a fever patient in ancient India.", "content": "At the bed-side of a fever patient in ancient India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988732"}
{"pmid": "20988733", "title": "Diseases of the middle age and later-on.", "content": "Diseases of the middle age and later-on.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988733"}
{"pmid": "20988734", "title": "Labour a problem of the mofussils.", "content": "Labour a problem of the mofussils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988734"}
{"pmid": "20988735", "title": "The predilection of atherosclerosis for the coronary arteries.", "content": "The predilection of atherosclerosis for the coronary arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988735"}
{"pmid": "20988736", "title": "The subcutaneous use of heparin in anticoagulation therapy.", "content": "The subcutaneous use of heparin in anticoagulation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988736"}
{"pmid": "20988737", "title": "Infectious lymphocytesis in brothers.", "content": "Infectious lymphocytesis in brothers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988737"}
{"pmid": "20988738", "title": "Dermatitis from penicillin.", "content": "Dermatitis from penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988738"}
{"pmid": "20988740", "title": "Agranulocytosis induced by aminopyrine suppositories; recovery following the use of penicillin in a highly allergic individual.", "content": "Agranulocytosis induced by aminopyrine suppositories; recovery following the use of penicillin in a highly allergic individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988740"}
{"pmid": "20988739", "title": "Massive gastrointestinal hemorrhage.", "content": "Massive gastrointestinal hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988739"}
{"pmid": "20988741", "title": "Early ambulation following surgical procedures.", "content": "Early ambulation following surgical procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988741"}
{"pmid": "20988742", "title": "The functional consequences of acute coronary occlusion.", "content": "The functional consequences of acute coronary occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988742"}
{"pmid": "20988743", "title": "A resume of the foreign bodies removed from food and air passages from October 1, 1944, to October 1, 1945.", "content": "A resume of the foreign bodies removed from food and air passages from October 1, 1944, to October 1, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988743"}
{"pmid": "20988744", "title": "Some recent advances in tropical medicine.", "content": "Some recent advances in tropical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988744"}
{"pmid": "20988746", "title": "Studies on endemic pneumonia of the albino rat; the transmission of a communicable disease to mice from naturally infected rats.", "content": "Studies on endemic pneumonia of the albino rat; the transmission of a communicable disease to mice from naturally infected rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988746"}
{"pmid": "20988745", "title": "St. Louis encephalitis; infection of chicken mites, dermanyssus gallinae, by feeding on chickens with viremia; transovarian passage of virus into the second generation.", "content": "St. Louis encephalitis; infection of chicken mites, dermanyssus gallinae, by feeding on chickens with viremia; transovarian passage of virus into the second generation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988745"}
{"pmid": "20988747", "title": "Studies on endemic pneumonia of the albino rat; the nature of the causal agent in experimentally infected mice.", "content": "Studies on endemic pneumonia of the albino rat; the nature of the causal agent in experimentally infected mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988747"}
{"pmid": "20988748", "title": "Influence of experimental kidney damage on histochemically demonstrable lipase activity in the rat; comparison with alkaline phosphatase activity.", "content": "Influence of experimental kidney damage on histochemically demonstrable lipase activity in the rat; comparison with alkaline phosphatase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988748"}
{"pmid": "20988749", "title": "A rickettsial infection in Canadian voles.", "content": "A rickettsial infection in Canadian voles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988749"}
{"pmid": "20988750", "title": "Fractionation of mammalian liver cells by differential centrifugation; problems, methods, and preparation of extract.", "content": "Fractionation of mammalian liver cells by differential centrifugation; problems, methods, and preparation of extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988750"}
{"pmid": "20988751", "title": "Fractionation of mammalian liver cells by differential centrifugation; experimental procedures and results.", "content": "Fractionation of mammalian liver cells by differential centrifugation; experimental procedures and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988751"}
{"pmid": "20988752", "title": "Mobilization of basophile substance (ribonucleic acid) in the cytoplasm of liver cells with the production of tumors by butter yellow.", "content": "Mobilization of basophile substance (ribonucleic acid) in the cytoplasm of liver cells with the production of tumors by butter yellow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988752"}
{"pmid": "20988753", "title": "Localization of ribonucleic acid in the cytoplasm of liver cells.", "content": "Localization of ribonucleic acid in the cytoplasm of liver cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988753"}
{"pmid": "20988754", "title": "Observations on the keeping properties of adrenalineprocaine solutions and tablets.", "content": "Observations on the keeping properties of adrenalineprocaine solutions and tablets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988754"}
{"pmid": "20988755", "title": "Some observations on cases of ascites in Hyderabad-Deccan: ascites associated with nutritional deficiency.", "content": "Some observations on cases of ascites in Hyderabad-Deccan: ascites associated with nutritional deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988755"}
{"pmid": "20988756", "title": "Genesis of nystagmus.", "content": "Genesis of nystagmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988756"}
{"pmid": "20988757", "title": "Hygiene publicity and health education.", "content": "Hygiene publicity and health education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988757"}
{"pmid": "20988758", "title": "Pharmacy bill in the Central Assembly.", "content": "Pharmacy bill in the Central Assembly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988758"}
{"pmid": "20988759", "title": "The treatment of anemia in general practice.", "content": "The treatment of anemia in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988759"}
{"pmid": "20988760", "title": "A rare accident. [Finger].", "content": "A rare accident. [Finger].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988760"}
{"pmid": "20988761", "title": "Acute myocardial infarction among young adults.", "content": "Acute myocardial infarction among young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988761"}
{"pmid": "20988762", "title": "The historical background of malaria; a reconsideration.", "content": "The historical background of malaria; a reconsideration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988762"}
{"pmid": "20988763", "title": "Amebiasis masquerading as portal cirrhosis.", "content": "Amebiasis masquerading as portal cirrhosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988763"}
{"pmid": "20988764", "title": "Case report of congenital applesia of the pylorus.", "content": "Case report of congenital applesia of the pylorus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988764"}
{"pmid": "20988765", "title": "A case of coartation of the aorta (adult type) with the Wolff-Parkinson-White syndrome.", "content": "A case of coartation of the aorta (adult type) with the Wolff-Parkinson-White syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988765"}
{"pmid": "20988777", "title": "Otitis externa.", "content": "Otitis externa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988777"}
{"pmid": "20988779", "title": "Therapeutic abuse of thyroid substance.", "content": "Therapeutic abuse of thyroid substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988779"}
{"pmid": "20988778", "title": "Benadryl in hay fever, asthma, and vasomotor rhinitis.", "content": "Benadryl in hay fever, asthma, and vasomotor rhinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988778"}
{"pmid": "20988780", "title": "Adoption procedure and medical practice under the new law; the role of the physician.", "content": "Adoption procedure and medical practice under the new law; the role of the physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988780"}
{"pmid": "20988781", "title": "Cancer education in a rural area.", "content": "Cancer education in a rural area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988781"}
{"pmid": "20988782", "title": "Compulsory health insurance.", "content": "Compulsory health insurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988782"}
{"pmid": "20988783", "title": "Injuries to the hand, with particular reference to indications for primary and secondary nerve and tendon repair.", "content": "Injuries to the hand, with particular reference to indications for primary and secondary nerve and tendon repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988783"}
{"pmid": "20988784", "title": "Present status of immunization procedures.", "content": "Present status of immunization procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988784"}
{"pmid": "20988785", "title": "Small town practice.", "content": "Small town practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988785"}
{"pmid": "20988786", "title": "Precancerous lesions of the rectum and colon: diagnosis and treatment.", "content": "Precancerous lesions of the rectum and colon: diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988786"}
{"pmid": "20988787", "title": "Radiological survey of the urinary tract; excretion urography.", "content": "Radiological survey of the urinary tract; excretion urography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988787"}
{"pmid": "20988788", "title": "Tropical medicine; aspects of significance to the American physician.", "content": "Tropical medicine; aspects of significance to the American physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988788"}
{"pmid": "20988789", "title": "Inguinal hernia.", "content": "Inguinal hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988789"}
{"pmid": "20988790", "title": "The treatment of pyogenic infections of the central nervous system.", "content": "The treatment of pyogenic infections of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988790"}
{"pmid": "20988794", "title": "New alignment.", "content": "New alignment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988794"}
{"pmid": "20988795", "title": "Blackwater fever in Rhodes.", "content": "Blackwater fever in Rhodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988795"}
{"pmid": "20988796", "title": "The problem of demyelination.", "content": "The problem of demyelination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988796"}
{"pmid": "20988797", "title": "New technic of enumeration and differentiation of leucocytes.", "content": "New technic of enumeration and differentiation of leucocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988797"}
{"pmid": "20988798", "title": "The mechanics and characteristics of the cough.", "content": "The mechanics and characteristics of the cough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988798"}
{"pmid": "20988799", "title": "Provisional diagnosis; nephrosis? nephritis?.", "content": "Provisional diagnosis; nephrosis? nephritis?.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988799"}
{"pmid": "20988800", "title": "Appendicitis, past and present.", "content": "Appendicitis, past and present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988800"}
{"pmid": "20988801", "title": "Idiopathic epilepsy; etiologic considerations.", "content": "Idiopathic epilepsy; etiologic considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988801"}
{"pmid": "20988802", "title": "Malignant hypertension; its clinical meaning and pathological interpretation.", "content": "Malignant hypertension; its clinical meaning and pathological interpretation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988802"}
{"pmid": "20988803", "title": "RESUSCITATION methods.", "content": "RESUSCITATION methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988803"}
{"pmid": "20988804", "title": "Jaundice.", "content": "Jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988804"}
{"pmid": "20988805", "title": "The use of blood derivatives.", "content": "The use of blood derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988805"}
{"pmid": "20988807", "title": "A review of the early work on adrenal cortical extract.", "content": "A review of the early work on adrenal cortical extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988807"}
{"pmid": "20988806", "title": "Fluid balance.", "content": "Fluid balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988806"}
{"pmid": "20988808", "title": "The biological significance of surfaces.", "content": "The biological significance of surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988808"}
{"pmid": "20988809", "title": "Clinical lessons from prisoner of war hospitals in the Far East (Burma and Siam).", "content": "Clinical lessons from prisoner of war hospitals in the Far East (Burma and Siam).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988809"}
{"pmid": "20988810", "title": "Ulcer of the leg.", "content": "Ulcer of the leg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988810"}
{"pmid": "20988811", "title": "Clinical lessons from prisoner of war hospitals in the Far East.", "content": "Clinical lessons from prisoner of war hospitals in the Far East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988811"}
{"pmid": "20988812", "title": "Cholera.", "content": "Cholera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988812"}
{"pmid": "20988813", "title": "Dysentery.", "content": "Dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988813"}
{"pmid": "20988814", "title": "Tropical ulcers.", "content": "Tropical ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988814"}
{"pmid": "20988815", "title": "Observations by a pathologist during three and a half years as a prisoner of war in Malaya and Thailand.", "content": "Observations by a pathologist during three and a half years as a prisoner of war in Malaya and Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988815"}
{"pmid": "20988816", "title": "Medical aspect of the Singapore captivity.", "content": "Medical aspect of the Singapore captivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988816"}
{"pmid": "20988817", "title": "Some medical experiences as a prisoner of war.", "content": "Some medical experiences as a prisoner of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988817"}
{"pmid": "20988818", "title": "Experiences as a prisoner of war in Japan.", "content": "Experiences as a prisoner of war in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988818"}
{"pmid": "20988819", "title": "Surgical experiences as a prisoner of war.", "content": "Surgical experiences as a prisoner of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988819"}
{"pmid": "20988820", "title": "RESEARCH at the Kanematsu Institute.", "content": "RESEARCH at the Kanematsu Institute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988820"}
{"pmid": "20988821", "title": "Private practice and the V.D. scheme.", "content": "Private practice and the V.D. scheme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988821"}
{"pmid": "20988822", "title": "Juvenile delinquency and adult crime.", "content": "Juvenile delinquency and adult crime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988822"}
{"pmid": "20988823", "title": "Vaginal or abdominal hysterectomy?", "content": "Vaginal or abdominal hysterectomy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988823"}
{"pmid": "20988824", "title": "Case report of an adenocarcinoma of the ileum.", "content": "Case report of an adenocarcinoma of the ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988824"}
{"pmid": "20988825", "title": "Problems in infancy.", "content": "Problems in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988825"}
{"pmid": "20988826", "title": "Cancer of the oesophagus.", "content": "Cancer of the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988826"}
{"pmid": "20988827", "title": "The Middlesex Hospital.", "content": "The Middlesex Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988827"}
{"pmid": "20988829", "title": "Headache.", "content": "Headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988829"}
{"pmid": "20988828", "title": "Two hundred years in medicine.", "content": "Two hundred years in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988828"}
{"pmid": "20988830", "title": "Recent public health trends in dentistry.", "content": "Recent public health trends in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988830"}
{"pmid": "20988831", "title": "The surgical treatment of biliary disease.", "content": "The surgical treatment of biliary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988831"}
{"pmid": "20988837", "title": "Tularemia in New York State.", "content": "Tularemia in New York State.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988837"}
{"pmid": "20988838", "title": "Ulcers about the anorectum.", "content": "Ulcers about the anorectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988838"}
{"pmid": "20988839", "title": "The stem pessary for dysmenorrhea.", "content": "The stem pessary for dysmenorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988839"}
{"pmid": "20988840", "title": "Tropical encephalopathy; malaria and solar etiology.", "content": "Tropical encephalopathy; malaria and solar etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988840"}
{"pmid": "20988841", "title": "The recrudescence of syphilis in New York State.", "content": "The recrudescence of syphilis in New York State.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988841"}
{"pmid": "20988842", "title": "Eradication of breast cancer, its feasibility and consequences; a reply.", "content": "Eradication of breast cancer, its feasibility and consequences; a reply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988842"}
{"pmid": "20988843", "title": "The treatment of lymphogranuloma venereum and granuloma inguinale.", "content": "The treatment of lymphogranuloma venereum and granuloma inguinale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988843"}
{"pmid": "20988844", "title": "Femoral hernial appendicitis in an aged individual.", "content": "Femoral hernial appendicitis in an aged individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988844"}
{"pmid": "20988845", "title": "Thrush as sequel to penicillin treatment.", "content": "Thrush as sequel to penicillin treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988845"}
{"pmid": "20988846", "title": "Pregnancy in hypertensive disease followed by thoracolumbar sympathectomy with renal biopsy and complete recovery.", "content": "Pregnancy in hypertensive disease followed by thoracolumbar sympathectomy with renal biopsy and complete recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988846"}
{"pmid": "20988847", "title": "Epilepsy.", "content": "Epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988847"}
{"pmid": "20988848", "title": "Symposium on head injuries; diagnosis and management for first forty-eight hours.", "content": "Symposium on head injuries; diagnosis and management for first forty-eight hours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988848"}
{"pmid": "20988849", "title": "Delayed surgical complications of head injuries.", "content": "Delayed surgical complications of head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988849"}
{"pmid": "20988850", "title": "Psychiatric aspects of head injury.", "content": "Psychiatric aspects of head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988850"}
{"pmid": "20988851", "title": "Head injuries; follow-up studies after forty-eight hours.", "content": "Head injuries; follow-up studies after forty-eight hours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988851"}
{"pmid": "20988852", "title": "Malaria; a problem in the care of the military service veteran.", "content": "Malaria; a problem in the care of the military service veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988852"}
{"pmid": "20988853", "title": "Spontaneous cerebral hemorrhage in a patient with essential hypertension.", "content": "Spontaneous cerebral hemorrhage in a patient with essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988853"}
{"pmid": "20988854", "title": "Chronic subdural hematoma following minor trauma.", "content": "Chronic subdural hematoma following minor trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988854"}
{"pmid": "20988855", "title": "Postoperative salt intolerance.", "content": "Postoperative salt intolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988855"}
{"pmid": "20988856", "title": "Fluid therapy in burns.", "content": "Fluid therapy in burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988856"}
{"pmid": "20988857", "title": "Transverse abdominal incisions and early postoperative ambulation.", "content": "Transverse abdominal incisions and early postoperative ambulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988857"}
{"pmid": "20988858", "title": "Postoperative pulmonary complications; their prevention and treatment.", "content": "Postoperative pulmonary complications; their prevention and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988858"}
{"pmid": "20988859", "title": "The vaginal smear; its value and significance in diagnosis of uterine carcinoma.", "content": "The vaginal smear; its value and significance in diagnosis of uterine carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988859"}
{"pmid": "20988860", "title": "Cosmetic reduction of full, everted lower lip.", "content": "Cosmetic reduction of full, everted lower lip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988860"}
{"pmid": "20988861", "title": "Criteria for the use of penicillin in empyema.", "content": "Criteria for the use of penicillin in empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988861"}
{"pmid": "20988862", "title": "Rheumatic fever here and in the European Theatre of Operations.", "content": "Rheumatic fever here and in the European Theatre of Operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988862"}
{"pmid": "20988863", "title": "Of interest to Dalhousians old and new.", "content": "Of interest to Dalhousians old and new.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988863"}
{"pmid": "20988864", "title": "Pneumococcal meningitis; case reports.", "content": "Pneumococcal meningitis; case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988864"}
{"pmid": "20988865", "title": "The work of the air evacuation section overseas.", "content": "The work of the air evacuation section overseas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988865"}
{"pmid": "20988866", "title": "The hazards of tropical diseases as a result of World War II.", "content": "The hazards of tropical diseases as a result of World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988866"}
{"pmid": "20988867", "title": "Poliomyelitis analysis.", "content": "Poliomyelitis analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988867"}
{"pmid": "20988868", "title": "Observations on an epidemic of poliomyelitis.", "content": "Observations on an epidemic of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988868"}
{"pmid": "20988869", "title": "Rupture of the uterus.", "content": "Rupture of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988869"}
{"pmid": "20988871", "title": "Forever as he rides [Med. history of Ohio].", "content": "Forever as he rides [Med. history of Ohio].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988871"}
{"pmid": "20988870", "title": "Propagating axillary and subclavian venous thrombosis with extension into the dural sinuses and intracerebral veins.", "content": "Propagating axillary and subclavian venous thrombosis with extension into the dural sinuses and intracerebral veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988870"}
{"pmid": "20988872", "title": "O.S.M.A. program for home-town treatment of disabled veterans accepted; effective July 1; all members urged to sign up at once.", "content": "O.S.M.A. program for home-town treatment of disabled veterans accepted; effective July 1; all members urged to sign up at once.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988872"}
{"pmid": "20988873", "title": "Skin diseases due to vitamin deficiencies.", "content": "Skin diseases due to vitamin deficiencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988873"}
{"pmid": "20988874", "title": "Nasal injuries and their implications.", "content": "Nasal injuries and their implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988874"}
{"pmid": "20988875", "title": "Urologic conditions associated with pain in the right lower quadrant.", "content": "Urologic conditions associated with pain in the right lower quadrant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988875"}
{"pmid": "20988876", "title": "Ocular tumors in a rural practice.", "content": "Ocular tumors in a rural practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988876"}
{"pmid": "20988877", "title": "Treatment of macrocytic anemia with synthetic L. casei factor (folic acid).", "content": "Treatment of macrocytic anemia with synthetic L. casei factor (folic acid).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988877"}
{"pmid": "20988878", "title": "A new truss for inguinal hernia in the infant.", "content": "A new truss for inguinal hernia in the infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988878"}
{"pmid": "20988879", "title": "The rationale of the blood sedimentation rate.", "content": "The rationale of the blood sedimentation rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988879"}
{"pmid": "20988880", "title": "The blood sedimentation rate; a critical clinical survey.", "content": "The blood sedimentation rate; a critical clinical survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988880"}
{"pmid": "20988881", "title": "Methods of estimating the blood sedimentation rate.", "content": "Methods of estimating the blood sedimentation rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988881"}
{"pmid": "20988882", "title": "The blood sedimentation rate in rheumatoid arthritis and allied conditions.", "content": "The blood sedimentation rate in rheumatoid arthritis and allied conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988882"}
{"pmid": "20988883", "title": "The blood sedimentation rate in pulmonary tuberculosis.", "content": "The blood sedimentation rate in pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988883"}
{"pmid": "20988884", "title": "The blood sedimentation rate in rheumatic fever.", "content": "The blood sedimentation rate in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988884"}
{"pmid": "20988885", "title": "Sea-sickness.", "content": "Sea-sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988885"}
{"pmid": "20988886", "title": "Ice and ice cream.", "content": "Ice and ice cream.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988886"}
{"pmid": "20988887", "title": "The early recognition of disease; orthopaedic disabilities and their treatment.", "content": "The early recognition of disease; orthopaedic disabilities and their treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988887"}
{"pmid": "20988888", "title": "Ophthalmia neonatorum.", "content": "Ophthalmia neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988888"}
{"pmid": "20988895", "title": "Diverticulitis gangrenosa.", "content": "Diverticulitis gangrenosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988895"}
{"pmid": "20988917", "title": "Hemophilus influenzae meningitis with recovery.", "content": "Hemophilus influenzae meningitis with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988917"}
{"pmid": "20988937", "title": "Description of an outbreak of beriberi; with special reference to the aetiology of beriberi and epidemic dropsy.", "content": "Description of an outbreak of beriberi; with special reference to the aetiology of beriberi and epidemic dropsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988937"}
{"pmid": "20988938", "title": "The heart in anaemia.", "content": "The heart in anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988938"}
{"pmid": "20988939", "title": "Complete congenital agenesis of a lung.", "content": "Complete congenital agenesis of a lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988939"}
{"pmid": "20988940", "title": "Anomalies of intestinal absorption of fat; the determination and significance of faecal fat.", "content": "Anomalies of intestinal absorption of fat; the determination and significance of faecal fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988940"}
{"pmid": "20988933", "title": "Acute appendicitis.", "content": "Acute appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988933"}
{"pmid": "20988935", "title": "A case of anaemia following pneumonia.", "content": "A case of anaemia following pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988935"}
{"pmid": "20988936", "title": "A case of acute peritonitis in association with amoebic dysentery.", "content": "A case of acute peritonitis in association with amoebic dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988936"}
{"pmid": "20988934", "title": "A case of bone tumour for diagnosis.", "content": "A case of bone tumour for diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988934"}
{"pmid": "20988966", "title": "The virus type of infectious hepatitis.", "content": "The virus type of infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988966"}
{"pmid": "20988967", "title": "Progress in cerebral palsy.", "content": "Progress in cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988967"}
{"pmid": "20988968", "title": "A preliminary report on the Crawford Allen Hospital for rheumatic children.", "content": "A preliminary report on the Crawford Allen Hospital for rheumatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988968"}
{"pmid": "20988969", "title": "The evolution of the medical record.", "content": "The evolution of the medical record.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988969"}
{"pmid": "20988970", "title": "CASH sickness in Rhode Island.", "content": "CASH sickness in Rhode Island.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988970"}
{"pmid": "20988971", "title": "Medical needs of the rural communities.", "content": "Medical needs of the rural communities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988971"}
{"pmid": "20988972", "title": "Tuberculosis in the Bantu.", "content": "Tuberculosis in the Bantu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988972"}
{"pmid": "20988973", "title": "Need prostatectomies soak?", "content": "Need prostatectomies soak?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988973"}
{"pmid": "20988974", "title": "Chronic essential pentosuria, with a report of a case.", "content": "Chronic essential pentosuria, with a report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988974"}
{"pmid": "20988975", "title": "Fenestration for otosclerosis.", "content": "Fenestration for otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988975"}
{"pmid": "20988976", "title": "Radioactive phosphorus.", "content": "Radioactive phosphorus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988976"}
{"pmid": "20988977", "title": "Pilonidal sinus.", "content": "Pilonidal sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988977"}
{"pmid": "20988978", "title": "Complications of anaesthesia: an illustrative case.", "content": "Complications of anaesthesia: an illustrative case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988978"}
{"pmid": "20988979", "title": "A case of diaphragmatic hernia with obstruction.", "content": "A case of diaphragmatic hernia with obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988979"}
{"pmid": "20988980", "title": "Arterial embolism; with a case report.", "content": "Arterial embolism; with a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988980"}
{"pmid": "20988981", "title": "NEW era developing in struggle against venereal diseases.", "content": "NEW era developing in struggle against venereal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988981"}
{"pmid": "20988982", "title": "TUBERCULOSIS control in the United States.", "content": "TUBERCULOSIS control in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988982"}
{"pmid": "20988983", "title": "CODE of standards for advertisements of medicines and treatments of the Newspaper Press Union of South Africa.", "content": "CODE of standards for advertisements of medicines and treatments of the Newspaper Press Union of South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20988983"}
{"pmid": "20989004", "title": "Dysenteric disorders.", "content": "Dysenteric disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989004"}
{"pmid": "20989006", "title": "LONGEVITY of life without food or water.", "content": "LONGEVITY of life without food or water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989006"}
{"pmid": "20989005", "title": "Bites and stings.", "content": "Bites and stings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989005"}
{"pmid": "20989007", "title": "Chemotherapy.", "content": "Chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989007"}
{"pmid": "20989008", "title": "Neurosurgical experiences in the lumbago-sciatic syndrome.", "content": "Neurosurgical experiences in the lumbago-sciatic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989008"}
{"pmid": "20989009", "title": "History of hemorrhoidal surgery.", "content": "History of hemorrhoidal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989009"}
{"pmid": "20989010", "title": "Spinal anesthesia; with special reference to the use of a procaine-pontocaine mixture.", "content": "Spinal anesthesia; with special reference to the use of a procaine-pontocaine mixture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989010"}
{"pmid": "20989011", "title": "Aberrant pancreas in the duodenum.", "content": "Aberrant pancreas in the duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989011"}
{"pmid": "20989012", "title": "The prevention and control of disturbances of protein metabolism in Rocky Mountain spotted fever; the value of forced feedings of a high-protein diet and of the administration of specific antiserum.", "content": "The prevention and control of disturbances of protein metabolism in Rocky Mountain spotted fever; the value of forced feedings of a high-protein diet and of the administration of specific antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989012"}
{"pmid": "20989014", "title": "Retention and excretion of manganese dioxide dispersions administered intravenously to humans.", "content": "Retention and excretion of manganese dioxide dispersions administered intravenously to humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989014"}
{"pmid": "20989013", "title": "Selective radiation obtained by the intravenous administration of colloidal radioactive isotopes in diseases of the lymphoid system.", "content": "Selective radiation obtained by the intravenous administration of colloidal radioactive isotopes in diseases of the lymphoid system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989013"}
{"pmid": "20989015", "title": "The use of radium and roentgen rays in the treatment of hyperplastic lymphoid tissue in the nasopharynx and pharynx.", "content": "The use of radium and roentgen rays in the treatment of hyperplastic lymphoid tissue in the nasopharynx and pharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989015"}
{"pmid": "20989016", "title": "Roentgenological consideration of gastro-intestinal disturbances with special reference to the stomach and duodenum.", "content": "Roentgenological consideration of gastro-intestinal disturbances with special reference to the stomach and duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989016"}
{"pmid": "20989017", "title": "Perforated peptic ulcers in naval personnel.", "content": "Perforated peptic ulcers in naval personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989017"}
{"pmid": "20989018", "title": "Estrogenic hormones, often only a psychotherapeutic agent.", "content": "Estrogenic hormones, often only a psychotherapeutic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989018"}
{"pmid": "20989020", "title": "A progress note on medical education in South Carolina.", "content": "A progress note on medical education in South Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989020"}
{"pmid": "20989019", "title": "Management of some common obstetrical complications in general practice.", "content": "Management of some common obstetrical complications in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989019"}
{"pmid": "20989021", "title": "Malaria in war.", "content": "Malaria in war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989021"}
{"pmid": "20989022", "title": "Penicillin in subacute bacterial endocarditis.", "content": "Penicillin in subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989022"}
{"pmid": "20989023", "title": "Some reflections on the ideal hospital of the future.", "content": "Some reflections on the ideal hospital of the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989023"}
{"pmid": "20989024", "title": "Some reflections on the evolution of medicine.", "content": "Some reflections on the evolution of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989024"}
{"pmid": "20989025", "title": "Cyclopropane anaesthesia.", "content": "Cyclopropane anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989025"}
{"pmid": "20989026", "title": "Electrical convulsant therapy.", "content": "Electrical convulsant therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989026"}
{"pmid": "20989029", "title": "Inhaled and swallowed foreign bodies.", "content": "Inhaled and swallowed foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989029"}
{"pmid": "20989027", "title": "Currents and eddies in practice.", "content": "Currents and eddies in practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989027"}
{"pmid": "20989028", "title": "Deposition at the adjourned inquest on the death of four firewatchers.", "content": "Deposition at the adjourned inquest on the death of four firewatchers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989028"}
{"pmid": "20989033", "title": "The training of the graduate nurse.", "content": "The training of the graduate nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989033"}
{"pmid": "20989034", "title": "Compulsory federal sickness insurance.", "content": "Compulsory federal sickness insurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989034"}
{"pmid": "20989035", "title": "The diagnosis of respiratory allergy.", "content": "The diagnosis of respiratory allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989035"}
{"pmid": "20989036", "title": "Spinal anesthesia.", "content": "Spinal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989036"}
{"pmid": "20989037", "title": "Management of adenomatous goiters.", "content": "Management of adenomatous goiters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989037"}
{"pmid": "20989039", "title": "Primary virus mastitis from mumps.", "content": "Primary virus mastitis from mumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989039"}
{"pmid": "20989038", "title": "The skin test as a suggested aid in the diagnosis of Salmonella suipestifer; a case report.", "content": "The skin test as a suggested aid in the diagnosis of Salmonella suipestifer; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989038"}
{"pmid": "20989040", "title": "Spontaneous passage of open safety pin from esophagus into stomach with point of pin directed downward.", "content": "Spontaneous passage of open safety pin from esophagus into stomach with point of pin directed downward.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989040"}
{"pmid": "20989041", "title": "Tension pneumothorax from rupture of esophagus.", "content": "Tension pneumothorax from rupture of esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989041"}
{"pmid": "20989042", "title": "Patent ductus arteriosus.", "content": "Patent ductus arteriosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989042"}
{"pmid": "20989043", "title": "Solving the problem of the toxicity of new chemicals in industry.", "content": "Solving the problem of the toxicity of new chemicals in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989043"}
{"pmid": "20989044", "title": "Oxygen treatment for chlorine gas exposures.", "content": "Oxygen treatment for chlorine gas exposures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989044"}
{"pmid": "20989045", "title": "Mustard gas burns; clinical experiences.", "content": "Mustard gas burns; clinical experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989045"}
{"pmid": "20989046", "title": "The treatment of acute alcoholism by the general practitioner.", "content": "The treatment of acute alcoholism by the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989046"}
{"pmid": "20989047", "title": "Discussion of the symposium on acute and chronic alcoholism.", "content": "Discussion of the symposium on acute and chronic alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989047"}
{"pmid": "20989048", "title": "SCHOOL system for Army officers.", "content": "SCHOOL system for Army officers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989048"}
{"pmid": "20989049", "title": "CLINICAL and public health laboratories in the Army.", "content": "CLINICAL and public health laboratories in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989049"}
{"pmid": "20989050", "title": "TRIAL use of the new antimalarial drug chloroquine.", "content": "TRIAL use of the new antimalarial drug chloroquine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989050"}
{"pmid": "20989051", "title": "BRONCHOPULMONARY actinomycosis.", "content": "BRONCHOPULMONARY actinomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989051"}
{"pmid": "20989052", "title": "COEXISTING tuberculosis and coccidioidomycosis.", "content": "COEXISTING tuberculosis and coccidioidomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989052"}
{"pmid": "20989053", "title": "BLOOD transfusions in patients with severe injuries.", "content": "BLOOD transfusions in patients with severe injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989053"}
{"pmid": "20989054", "title": "RADAR pulses apparently harmless.", "content": "RADAR pulses apparently harmless.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989054"}
{"pmid": "20989055", "title": "ARMY battle deaths.", "content": "ARMY battle deaths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989055"}
{"pmid": "20989056", "title": "PRESCRIBING occupational therapy.", "content": "PRESCRIBING occupational therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989056"}
{"pmid": "20989057", "title": "PELVIC fitting hip control.", "content": "PELVIC fitting hip control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989057"}
{"pmid": "20989058", "title": "MEETING of Historical Advisory Board.", "content": "MEETING of Historical Advisory Board.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989058"}
{"pmid": "20989059", "title": "NEW training films.", "content": "NEW training films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989059"}
{"pmid": "20989060", "title": "SPECIAL disease hazards in basic training centers.", "content": "SPECIAL disease hazards in basic training centers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989060"}
{"pmid": "20989061", "title": "Smallpox among U.S. soldiers in Korea.", "content": "Smallpox among U.S. soldiers in Korea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989061"}
{"pmid": "20989062", "title": "Plan to control diphtheria in a general hospital.", "content": "Plan to control diphtheria in a general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989062"}
{"pmid": "20989063", "title": "Operation of an Army neurosyphilis center.", "content": "Operation of an Army neurosyphilis center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989063"}
{"pmid": "20989064", "title": "The psychology of sick call.", "content": "The psychology of sick call.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989064"}
{"pmid": "20989065", "title": "Plasma proteins in returning A.A.F. personnel.", "content": "Plasma proteins in returning A.A.F. personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989065"}
{"pmid": "20989066", "title": "Colds on two Aleutian islands.", "content": "Colds on two Aleutian islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989066"}
{"pmid": "20989067", "title": "Hysteria in military personnel.", "content": "Hysteria in military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989067"}
{"pmid": "20989068", "title": "Thrombophlebitis following tonsillectomy.", "content": "Thrombophlebitis following tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989068"}
{"pmid": "20989069", "title": "An improvised whirlpool.", "content": "An improvised whirlpool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989069"}
{"pmid": "20989070", "title": "Split skin grafts in the early closure of wounds.", "content": "Split skin grafts in the early closure of wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989070"}
{"pmid": "20989072", "title": "The American Army Medical Services in the field.", "content": "The American Army Medical Services in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989072"}
{"pmid": "20989071", "title": "Transfusion of defibrinated blood in P.O.W. camps at Chungkai and Nakom Paton, Thailand.", "content": "Transfusion of defibrinated blood in P.O.W. camps at Chungkai and Nakom Paton, Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989071"}
{"pmid": "20989073", "title": "Parachutists.", "content": "Parachutists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989073"}
{"pmid": "20989074", "title": "The nephron in nephritis.", "content": "The nephron in nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989074"}
{"pmid": "20989075", "title": "Regional block analgesia.", "content": "Regional block analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989075"}
{"pmid": "20989076", "title": "JENNER'S work and the present position of vaccination.", "content": "JENNER'S work and the present position of vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989076"}
{"pmid": "20989077", "title": "The Army's medical research program during World War II.", "content": "The Army's medical research program during World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989077"}
{"pmid": "20989078", "title": "Intra-abdominal surgical technic.", "content": "Intra-abdominal surgical technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989078"}
{"pmid": "20989079", "title": "Air evacuation of sick and wounded.", "content": "Air evacuation of sick and wounded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989079"}
{"pmid": "20989080", "title": "Visceral leishmaniasis.", "content": "Visceral leishmaniasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989080"}
{"pmid": "20989081", "title": "Duties of the military malariologist.", "content": "Duties of the military malariologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989081"}
{"pmid": "20989082", "title": "Why is neurosyphilis uncommon in the tropics?", "content": "Why is neurosyphilis uncommon in the tropics?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989082"}
{"pmid": "20989083", "title": "The Buie operation for the cure of infected pilonidal cysts.", "content": "The Buie operation for the cure of infected pilonidal cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989083"}
{"pmid": "20989084", "title": "Penicillin and bone grafting operations; evaluation of operations performed without penicillin and those performed with penicillin.", "content": "Penicillin and bone grafting operations; evaluation of operations performed without penicillin and those performed with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989084"}
{"pmid": "20989085", "title": "A convenient flexion-extension leg support for nerve surgery of the lower extremity.", "content": "A convenient flexion-extension leg support for nerve surgery of the lower extremity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989085"}
{"pmid": "20989086", "title": "Study and treatment of 27 cases of schistosomiasis mansoni with fuadin.", "content": "Study and treatment of 27 cases of schistosomiasis mansoni with fuadin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989086"}
{"pmid": "20989087", "title": "Protective cover for laboratory reagent bottles.", "content": "Protective cover for laboratory reagent bottles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989087"}
{"pmid": "20989094", "title": "Artrodesis tibiotarsiana.", "content": "Artrodesis tibiotarsiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989094"}
{"pmid": "20989098", "title": "Dextrocardia with situs inversus; report of eight cases with a review of the literature on dextrocardia.", "content": "Dextrocardia with situs inversus; report of eight cases with a review of the literature on dextrocardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989098"}
{"pmid": "20989097", "title": "Schistosomiasis and its control in Egypt.", "content": "Schistosomiasis and its control in Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989097"}
{"pmid": "20989099", "title": "Cancer in the naval service.", "content": "Cancer in the naval service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989099"}
{"pmid": "20989100", "title": "Some clinical problems of amebiasis.", "content": "Some clinical problems of amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989100"}
{"pmid": "20989101", "title": "Management of common eye, ear, nose, and throat conditions in Naval practice.", "content": "Management of common eye, ear, nose, and throat conditions in Naval practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989101"}
{"pmid": "20989102", "title": "Care of the paraplegic's urinary tract.", "content": "Care of the paraplegic's urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989102"}
{"pmid": "20989103", "title": "Emergency surgical measures aboard an APA during an amphibious invasion.", "content": "Emergency surgical measures aboard an APA during an amphibious invasion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989103"}
{"pmid": "20989104", "title": "Definitive surgical treatment of wounds of the colon and rectum.", "content": "Definitive surgical treatment of wounds of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989104"}
{"pmid": "20989105", "title": "Prespondylolisthesis; a study of 23 cases.", "content": "Prespondylolisthesis; a study of 23 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989105"}
{"pmid": "20989106", "title": "Alginate impression technique.", "content": "Alginate impression technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989106"}
{"pmid": "20989107", "title": "Insulin as a sedative in treatment of psychotic patients in a tropical hospital.", "content": "Insulin as a sedative in treatment of psychotic patients in a tropical hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989107"}
{"pmid": "20989108", "title": "Ingrown toenail; a simplified operative treatment.", "content": "Ingrown toenail; a simplified operative treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989108"}
{"pmid": "20989109", "title": "Women Reserves for overseas duty.", "content": "Women Reserves for overseas duty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989109"}
{"pmid": "20989110", "title": "Cystic disease of the lung.", "content": "Cystic disease of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989110"}
{"pmid": "20989111", "title": "Acute nonspecific thyroiditis following measles; report of a case.", "content": "Acute nonspecific thyroiditis following measles; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989111"}
{"pmid": "20989112", "title": "Penicillin in treatment of fulminating general peritonitis; report of a confirmed case.", "content": "Penicillin in treatment of fulminating general peritonitis; report of a confirmed case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989112"}
{"pmid": "20989113", "title": "Instructions for prosthetic patients.", "content": "Instructions for prosthetic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989113"}
{"pmid": "20989114", "title": "Replacement of missing teeth or acrylic dentures in the field.", "content": "Replacement of missing teeth or acrylic dentures in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989114"}
{"pmid": "20989115", "title": "Infarct of testicle; report of a case.", "content": "Infarct of testicle; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989115"}
{"pmid": "20989116", "title": "Penicillin in acute appendicitis; report of a case.", "content": "Penicillin in acute appendicitis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989116"}
{"pmid": "20989117", "title": "The ambulance boat.", "content": "The ambulance boat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989117"}
{"pmid": "20989118", "title": "Improved elbow joint for artificial arms; a preliminary report.", "content": "Improved elbow joint for artificial arms; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989118"}
{"pmid": "20989119", "title": "Malaria at a Caribbean base.", "content": "Malaria at a Caribbean base.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989119"}
{"pmid": "20989120", "title": "MILK marketing in India.", "content": "MILK marketing in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989120"}
{"pmid": "20989121", "title": "Emission bands of bromine.", "content": "Emission bands of bromine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989121"}
{"pmid": "20989122", "title": "Production of hypoprothrombinaemia in the rat by feeding sulphathiazole and its cure with synthetic vitamin K.", "content": "Production of hypoprothrombinaemia in the rat by feeding sulphathiazole and its cure with synthetic vitamin K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989122"}
{"pmid": "20989123", "title": "Occurrence of kanugin in the stem bark of Pongamia glabra.", "content": "Occurrence of kanugin in the stem bark of Pongamia glabra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989123"}
{"pmid": "20989124", "title": "The pH of sodium borate solutions, a useful buffer mixture.", "content": "The pH of sodium borate solutions, a useful buffer mixture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989124"}
{"pmid": "20989125", "title": "On the kinetics of enzyme reactions.", "content": "On the kinetics of enzyme reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989125"}
{"pmid": "20989126", "title": "Tamarind seed pectin.", "content": "Tamarind seed pectin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989126"}
{"pmid": "20989127", "title": "Tamarind seed pectin.", "content": "Tamarind seed pectin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989127"}
{"pmid": "20989128", "title": "Two varieties of Tachardina lobata.", "content": "Two varieties of Tachardina lobata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989128"}
{"pmid": "20989129", "title": "The Chinese origin of the word chemistry.", "content": "The Chinese origin of the word chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989129"}
{"pmid": "20989130", "title": "Chromosome numbers of two members of Thymelaeaceae.", "content": "Chromosome numbers of two members of Thymelaeaceae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989130"}
{"pmid": "20989132", "title": "Penicillin.", "content": "Penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989132"}
{"pmid": "20989140", "title": "Studies on industrial micro-organisms; vitamin requirements of some strains of yeast.", "content": "Studies on industrial micro-organisms; vitamin requirements of some strains of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989140"}
{"pmid": "20989141", "title": "Effect of thiamin, niacin and riboflavin on the growth of yeast.", "content": "Effect of thiamin, niacin and riboflavin on the growth of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989141"}
{"pmid": "20989142", "title": "The structure, function and synthesis of polysaccharides.", "content": "The structure, function and synthesis of polysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989142"}
{"pmid": "20989143", "title": "Contributions to the theory of chromatography.", "content": "Contributions to the theory of chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989143"}
{"pmid": "20989144", "title": "Phases in the drinking history of alcoholics.", "content": "Phases in the drinking history of alcoholics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989144"}
{"pmid": "20989145", "title": "Potentiation of the depressant action of alcohol by adrenalin.", "content": "Potentiation of the depressant action of alcohol by adrenalin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989145"}
{"pmid": "20989146", "title": "Group therapy in an outpatient clinic for the treatment of alcoholism.", "content": "Group therapy in an outpatient clinic for the treatment of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989146"}
{"pmid": "20989147", "title": "The alcohol problem and the law; the beginnings of the alcoholic-beverage control laws in America.", "content": "The alcohol problem and the law; the beginnings of the alcoholic-beverage control laws in America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989147"}
{"pmid": "20989149", "title": "A megavoltmeter for induction electron accelerators.", "content": "A megavoltmeter for induction electron accelerators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989149"}
{"pmid": "20989148", "title": "An apparatus for recording pressure on a spectrographic plate.", "content": "An apparatus for recording pressure on a spectrographic plate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989148"}
{"pmid": "20989150", "title": "A sensitive vacuum gauge with linear response.", "content": "A sensitive vacuum gauge with linear response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989150"}
{"pmid": "20989151", "title": "Laboratory pulse generator with variable time delay.", "content": "Laboratory pulse generator with variable time delay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989151"}
{"pmid": "20989152", "title": "Microtomy with a reciprocating circular knife and a mechanism for sharpening the knife.", "content": "Microtomy with a reciprocating circular knife and a mechanism for sharpening the knife.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989152"}
{"pmid": "20989153", "title": "Small mica window Geiger-Müller counter for measurements of radioactive isotopes in vivo.", "content": "Small mica window Geiger-Müller counter for measurements of radioactive isotopes in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989153"}
{"pmid": "20989155", "title": "OXYGEN-HYDROGEN indicator.", "content": "OXYGEN-HYDROGEN indicator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989155"}
{"pmid": "20989154", "title": "High precision achromatic auto-collimator.", "content": "High precision achromatic auto-collimator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989154"}
{"pmid": "20989156", "title": "New units for the measurement of radioactivity.", "content": "New units for the measurement of radioactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989156"}
{"pmid": "20989157", "title": "Color photomicrography.", "content": "Color photomicrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989157"}
{"pmid": "20989158", "title": "The natural history of yellow fever in Colombia.", "content": "The natural history of yellow fever in Colombia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989158"}
{"pmid": "20989159", "title": "The place of fear in the scheme of things.", "content": "The place of fear in the scheme of things.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989159"}
{"pmid": "20989160", "title": "The Western Museum Society of Cincinnati.", "content": "The Western Museum Society of Cincinnati.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989160"}
{"pmid": "20989161", "title": "Phase microscopy.", "content": "Phase microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989161"}
{"pmid": "20989162", "title": "Studies on Oxytricha bifaria; conjugation.", "content": "Studies on Oxytricha bifaria; conjugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989162"}
{"pmid": "20989163", "title": "Red water in La Jolla Bay in 1945.", "content": "Red water in La Jolla Bay in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989163"}
{"pmid": "20989164", "title": "Morphology of a new species of bat cestode, Hymenolepis roudabushi, and a note on Hymenolepis christensoni Macy.", "content": "Morphology of a new species of bat cestode, Hymenolepis roudabushi, and a note on Hymenolepis christensoni Macy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989164"}
{"pmid": "20989165", "title": "Progressive facial hemiatrophy, disseminated scleroderma and muscular cramps.", "content": "Progressive facial hemiatrophy, disseminated scleroderma and muscular cramps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989165"}
{"pmid": "20989166", "title": "Virus infection subsequent to tonsillectomy.", "content": "Virus infection subsequent to tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989166"}
{"pmid": "20989167", "title": "Middle and posterior fossa epidermoid tumor simulating multiple sclerosis.", "content": "Middle and posterior fossa epidermoid tumor simulating multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989167"}
{"pmid": "20989168", "title": "Remarks on localisation.", "content": "Remarks on localisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989168"}
{"pmid": "20989169", "title": "The neural factor in infarction.", "content": "The neural factor in infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989169"}
{"pmid": "20989170", "title": "Surgery's contribution to our knowledge of pituitary function.", "content": "Surgery's contribution to our knowledge of pituitary function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989170"}
{"pmid": "20989171", "title": "Structure and function of the cerebral cortex in the new-born cat (Felis domestica).", "content": "Structure and function of the cerebral cortex in the new-born cat (Felis domestica).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989171"}
{"pmid": "20989172", "title": "Sluder's syndrome of nasal ganglion neurosis due to irritative zone in the nasal mucosa.", "content": "Sluder's syndrome of nasal ganglion neurosis due to irritative zone in the nasal mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989172"}
{"pmid": "20989173", "title": "Effects of quadrigeminal lesions upon labyrinthine nystagmus.", "content": "Effects of quadrigeminal lesions upon labyrinthine nystagmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989173"}
{"pmid": "20989175", "title": "Some clinical manifestations of hypothalamic dysfunction.", "content": "Some clinical manifestations of hypothalamic dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989175"}
{"pmid": "20989174", "title": "Ultraspectrographic studies on cerebrospinal fluid.", "content": "Ultraspectrographic studies on cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989174"}
{"pmid": "20989176", "title": "Pancreo-pituitary hypoglycemia.", "content": "Pancreo-pituitary hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989176"}
{"pmid": "20989177", "title": "Factors causing massive spasm following transection of the cord in man.", "content": "Factors causing massive spasm following transection of the cord in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989177"}
{"pmid": "20989179", "title": "Compound injuries of the spinal cord.", "content": "Compound injuries of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989179"}
{"pmid": "20989178", "title": "Damage to peripheral nerves by high velocity missiles without a direct hit.", "content": "Damage to peripheral nerves by high velocity missiles without a direct hit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989178"}
{"pmid": "20989180", "title": "Experimental observations on the use of stainless steel for cranioplasty; comparison with tantalum.", "content": "Experimental observations on the use of stainless steel for cranioplasty; comparison with tantalum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989180"}
{"pmid": "20989181", "title": "Failure in early secondary repair of skull defects with tantalum.", "content": "Failure in early secondary repair of skull defects with tantalum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989181"}
{"pmid": "20989182", "title": "Observations upon the management of orbito-cranial wounds.", "content": "Observations upon the management of orbito-cranial wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989182"}
{"pmid": "20989183", "title": "Experiments on thrombosis of the superior longitudinal sinus.", "content": "Experiments on thrombosis of the superior longitudinal sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989183"}
{"pmid": "20989184", "title": "Ependymoma of spinal cord; subtotal intramedullary removal from syringomyelic cavity.", "content": "Ependymoma of spinal cord; subtotal intramedullary removal from syringomyelic cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989184"}
{"pmid": "20989185", "title": "Method of ventricular fluid replacement following ventriculography.", "content": "Method of ventricular fluid replacement following ventriculography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989185"}
{"pmid": "20989186", "title": "A removable suture method of nerve repair.", "content": "A removable suture method of nerve repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989186"}
{"pmid": "20989187", "title": "Twist drill guard for use in craniotomy.", "content": "Twist drill guard for use in craniotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989187"}
{"pmid": "20989193", "title": "The tumour virus disseminated from filterable to non-filterable tumours.", "content": "The tumour virus disseminated from filterable to non-filterable tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989193"}
{"pmid": "20989194", "title": "The effect of treatment on the spleen of the golden hamster (Cricetus auratus) infected with Leishmania donovani.", "content": "The effect of treatment on the spleen of the golden hamster (Cricetus auratus) infected with Leishmania donovani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989194"}
{"pmid": "20989195", "title": "Immunity to homologous grafted skin; the suppression of cell division in grafts transplanted to immunized animals.", "content": "Immunity to homologous grafted skin; the suppression of cell division in grafts transplanted to immunized animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989195"}
{"pmid": "20989196", "title": "Immunity to homologous grafted skin; the relationship between the antigens of blood and skin.", "content": "Immunity to homologous grafted skin; the relationship between the antigens of blood and skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989196"}
{"pmid": "20989197", "title": "A serological investigation in hepatitis using the complement-fixation reaction.", "content": "A serological investigation in hepatitis using the complement-fixation reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989197"}
{"pmid": "20989198", "title": "A study of the formation, properties and partial purifications of leukotaxine.", "content": "A study of the formation, properties and partial purifications of leukotaxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989198"}
{"pmid": "20989188", "title": "Psychiatric social work with children who have epilepsy.", "content": "Psychiatric social work with children who have epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989188"}
{"pmid": "20989199", "title": "Further observations on the chemotherapy of experimental gas gangrene; flavazole, marfanil, V187 and V335.", "content": "Further observations on the chemotherapy of experimental gas gangrene; flavazole, marfanil, V187 and V335.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989199"}
{"pmid": "20989189", "title": "Some aspects of the treatment of the emotional problems of the tuberculous.", "content": "Some aspects of the treatment of the emotional problems of the tuberculous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989189"}
{"pmid": "20989200", "title": "Tumours produced by 2-anthramine.", "content": "Tumours produced by 2-anthramine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989200"}
{"pmid": "20989201", "title": "The early failure of breast feeding; a clinical study of its causes and their prevention.", "content": "The early failure of breast feeding; a clinical study of its causes and their prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989201"}
{"pmid": "20989202", "title": "Some observations on penicillin; its dosage and administration in infancy.", "content": "Some observations on penicillin; its dosage and administration in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989202"}
{"pmid": "20989203", "title": "Aerosol penicillin in the oxygen tent.", "content": "Aerosol penicillin in the oxygen tent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989203"}
{"pmid": "20989204", "title": "Penicillin in the treatment of neonatal sepsis.", "content": "Penicillin in the treatment of neonatal sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989204"}
{"pmid": "20989205", "title": "The sulphonamides in the treatment of infections in infancy.", "content": "The sulphonamides in the treatment of infections in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989205"}
{"pmid": "20989206", "title": "Rickets in Singapore.", "content": "Rickets in Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989206"}
{"pmid": "20989207", "title": "Dwarfism with retinal atrophy and deafness.", "content": "Dwarfism with retinal atrophy and deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989207"}
{"pmid": "20989208", "title": "Case of congenital atresia of the oesophagus with infantile pyloric stenosis.", "content": "Case of congenital atresia of the oesophagus with infantile pyloric stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989208"}
{"pmid": "20989209", "title": "Report of Child Psychology Sub-Committee, British Paediatric Association.", "content": "Report of Child Psychology Sub-Committee, British Paediatric Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989209"}
{"pmid": "20989212", "title": "The influence of vehicles on the action of drugs.", "content": "The influence of vehicles on the action of drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989212"}
{"pmid": "20989213", "title": "The effect of continued oral administration of lauric and myristic acid ester of colaminoformylmethylpyridinium chloride (emulsept) to the albino rat.", "content": "The effect of continued oral administration of lauric and myristic acid ester of colaminoformylmethylpyridinium chloride (emulsept) to the albino rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989213"}
{"pmid": "20989214", "title": "Determination of zinc oxide and bentonite in calamine lotion.", "content": "Determination of zinc oxide and bentonite in calamine lotion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989214"}
{"pmid": "20989215", "title": "The determination of estrone in oil solutions of estrogens.", "content": "The determination of estrone in oil solutions of estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989215"}
{"pmid": "20989216", "title": "A chemical study of two isomeric sodium hydroxymercuribenzoates.", "content": "A chemical study of two isomeric sodium hydroxymercuribenzoates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989216"}
{"pmid": "20989217", "title": "Studies in the preservation of liquid pharmaceutical preparations; the relationship between the preservative action of alcohol and the solid content of the preparation.", "content": "Studies in the preservation of liquid pharmaceutical preparations; the relationship between the preservative action of alcohol and the solid content of the preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989217"}
{"pmid": "20989218", "title": "The synthesis of some alpha, omega-bis-(3,4-dihydroxyphenyl) alkanes.", "content": "The synthesis of some alpha, omega-bis-(3,4-dihydroxyphenyl) alkanes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989218"}
{"pmid": "20989219", "title": "Pharmacology of lobelan and related compounds.", "content": "Pharmacology of lobelan and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989219"}
{"pmid": "20989220", "title": "The secretion of pancreatic juice in the presence of atropine or hyoscyamine in chronic fistula dogs.", "content": "The secretion of pancreatic juice in the presence of atropine or hyoscyamine in chronic fistula dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989220"}
{"pmid": "20989221", "title": "Studies on the pharmacology of fluoro acetate; species response to fluoroacetate.", "content": "Studies on the pharmacology of fluoro acetate; species response to fluoroacetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989221"}
{"pmid": "20989222", "title": "The response of the isolated frog heart to different barbiturates.", "content": "The response of the isolated frog heart to different barbiturates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989222"}
{"pmid": "20989223", "title": "The inhibition of cholinesterase by aromatic amino alcohols of the type Ar-CHOHCH2NR2.", "content": "The inhibition of cholinesterase by aromatic amino alcohols of the type Ar-CHOHCH2NR2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989223"}
{"pmid": "20989224", "title": "Myotropic spasmolytic, histaminolytic, and atropine-like actions of some derivatives of dimethy-laminoethyl benzhydryl ether hydrochloride (benadryl).", "content": "Myotropic spasmolytic, histaminolytic, and atropine-like actions of some derivatives of dimethy-laminoethyl benzhydryl ether hydrochloride (benadryl).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989224"}
{"pmid": "20989225", "title": "Anesthesia; the anesthetic action of isopropyl methyl ether.", "content": "Anesthesia; the anesthetic action of isopropyl methyl ether.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989225"}
{"pmid": "20989226", "title": "Blockade of the nicotine action on the blood pressure by thiazole-compounds (sulfathiazole and thiamine).", "content": "Blockade of the nicotine action on the blood pressure by thiazole-compounds (sulfathiazole and thiamine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989226"}
{"pmid": "20989227", "title": "Studies on the mechanism of action of sympathomimetic amines; the oxidation of tyramine by rat liver homogenates.", "content": "Studies on the mechanism of action of sympathomimetic amines; the oxidation of tyramine by rat liver homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989227"}
{"pmid": "20989228", "title": "An evaluation of the rhodamine B method for the determination of antimony.", "content": "An evaluation of the rhodamine B method for the determination of antimony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989228"}
{"pmid": "20989229", "title": "The tissue-distribution and excretion of four organic antimonials after single or repeated administration to normal hamsters.", "content": "The tissue-distribution and excretion of four organic antimonials after single or repeated administration to normal hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989229"}
{"pmid": "20989230", "title": "Chemotherapy of filariasis (Litomosoides carinii) in the cotton rat by the administration of stibanose (solustibosan).", "content": "Chemotherapy of filariasis (Litomosoides carinii) in the cotton rat by the administration of stibanose (solustibosan).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989230"}
{"pmid": "20989232", "title": "Primitive medicine; a contrast with modern practice.", "content": "Primitive medicine; a contrast with modern practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989232"}
{"pmid": "20989231", "title": "The site of action of narcotics on brain metabolism.", "content": "The site of action of narcotics on brain metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989231"}
{"pmid": "20989233", "title": "Peacetime implications of biological warfare.", "content": "Peacetime implications of biological warfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989233"}
{"pmid": "20989234", "title": "Venereal disease in pregnancy.", "content": "Venereal disease in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989234"}
{"pmid": "20989235", "title": "Some poisonous animals of the United States.", "content": "Some poisonous animals of the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989235"}
{"pmid": "20989236", "title": "The new National Formulary (VIII).", "content": "The new National Formulary (VIII).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989236"}
{"pmid": "20989237", "title": "The new Pharmacopoeia (XIII).", "content": "The new Pharmacopoeia (XIII).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989237"}
{"pmid": "20989238", "title": "The physiology of the rat in extreme anoxia.", "content": "The physiology of the rat in extreme anoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989238"}
{"pmid": "20989239", "title": "The renal clearance of essential amino acids; tryptophane, leucine, isoleucine and valine.", "content": "The renal clearance of essential amino acids; tryptophane, leucine, isoleucine and valine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989239"}
{"pmid": "20989240", "title": "Acclimatization to extreme heat and its effect on the ability to work in less severe environments.", "content": "Acclimatization to extreme heat and its effect on the ability to work in less severe environments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989240"}
{"pmid": "20989241", "title": "The bulbar inhibitory mechanism in concussion.", "content": "The bulbar inhibitory mechanism in concussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989241"}
{"pmid": "20989242", "title": "The renal clearance of thiosulfate with observations on its volume distribution.", "content": "The renal clearance of thiosulfate with observations on its volume distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989242"}
{"pmid": "20989243", "title": "Previous diet and the role of the kidney in the metabolism of the eviscerated rat.", "content": "Previous diet and the role of the kidney in the metabolism of the eviscerated rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989243"}
{"pmid": "20989244", "title": "Effect of muscular activity on bleeding volume of normal and shocked animals.", "content": "Effect of muscular activity on bleeding volume of normal and shocked animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989244"}
{"pmid": "20989245", "title": "Rate of water loss from the skin of the foot of normal and trench foot subjects.", "content": "Rate of water loss from the skin of the foot of normal and trench foot subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989245"}
{"pmid": "20989246", "title": "Are mass discharges characteristic of central autonomic structures?", "content": "Are mass discharges characteristic of central autonomic structures?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989246"}
{"pmid": "20989247", "title": "Sympathetico-adrenal discharges in hypophysectomized rats.", "content": "Sympathetico-adrenal discharges in hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989247"}
{"pmid": "20989248", "title": "The effect of hypoglycemia and age on the glycogen content of the various parts of the feline central nervous system.", "content": "The effect of hypoglycemia and age on the glycogen content of the various parts of the feline central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989248"}
{"pmid": "20989249", "title": "Oxygen consumption for men of various sizes in the simulated piloting of a plane.", "content": "Oxygen consumption for men of various sizes in the simulated piloting of a plane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989249"}
{"pmid": "20989250", "title": "The effect of different concentrations of pyridoxine hydrochloride on the work output of perfused frog muscles.", "content": "The effect of different concentrations of pyridoxine hydrochloride on the work output of perfused frog muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989250"}
{"pmid": "20989251", "title": "An investigation of bioelectric phenomena in mice and the development of a three-electrode method.", "content": "An investigation of bioelectric phenomena in mice and the development of a three-electrode method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989251"}
{"pmid": "20989252", "title": "The regulation of arterial blood pressure.", "content": "The regulation of arterial blood pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989252"}
{"pmid": "20989253", "title": "Some observations of the effects of training on pulse rate, blood pressure and endurance, in humans, using the step test (Harvard), treadmill and electrodynamic brake bicycle ergometer.", "content": "Some observations of the effects of training on pulse rate, blood pressure and endurance, in humans, using the step test (Harvard), treadmill and electrodynamic brake bicycle ergometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989253"}
{"pmid": "20989254", "title": "The value of alkalinizing agents in preventing the transition from impending to irreversible hemorrhagic shock.", "content": "The value of alkalinizing agents in preventing the transition from impending to irreversible hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989254"}
{"pmid": "20989255", "title": "A comparison of the effects of thiouracil and thyroidectomy on some phases of metabolism in the rat.", "content": "A comparison of the effects of thiouracil and thyroidectomy on some phases of metabolism in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989255"}
{"pmid": "20989256", "title": "Observations on interaction of nerve impulses in the gray matter and on the nature of central inhibition.", "content": "Observations on interaction of nerve impulses in the gray matter and on the nature of central inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989256"}
{"pmid": "20989257", "title": "Effect of hemorrhage on gastro-intestinal motility of dogs; a gradient of gastro-intestinal motility.", "content": "Effect of hemorrhage on gastro-intestinal motility of dogs; a gradient of gastro-intestinal motility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989257"}
{"pmid": "20989258", "title": "The influence of a placebo, body position and medication on motion sickness.", "content": "The influence of a placebo, body position and medication on motion sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989258"}
{"pmid": "20989259", "title": "Circulatory effects of partial cerebral ischemia.", "content": "Circulatory effects of partial cerebral ischemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989259"}
{"pmid": "20989260", "title": "The acid tolerance of the dog heart.", "content": "The acid tolerance of the dog heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989260"}
{"pmid": "20989262", "title": "Total pancreatectomy for carcinoma of the pancreas in a diabetic person.", "content": "Total pancreatectomy for carcinoma of the pancreas in a diabetic person.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989262"}
{"pmid": "20989261", "title": "Anaphylactic shock in dogs with an Eck fistula.", "content": "Anaphylactic shock in dogs with an Eck fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989261"}
{"pmid": "20989263", "title": "Parenteral administration of fluids during the early care of battle casualties.", "content": "Parenteral administration of fluids during the early care of battle casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989263"}
{"pmid": "20989264", "title": "Pulsating benign giant cell tumors of bone.", "content": "Pulsating benign giant cell tumors of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989264"}
{"pmid": "20989265", "title": "Injection into pericardial sac and ligation of coronary artery of the rat.", "content": "Injection into pericardial sac and ligation of coronary artery of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989265"}
{"pmid": "20989266", "title": "Pilonidal sinus; a review of 130 consecutive cases in which patients were treated by closure; a new closed operative method and management.", "content": "Pilonidal sinus; a review of 130 consecutive cases in which patients were treated by closure; a new closed operative method and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989266"}
{"pmid": "20989267", "title": "New and successful closed operative procedure for pilonidal sinus; gluteus maximus mobilization; a sliding muscle graft procedure.", "content": "New and successful closed operative procedure for pilonidal sinus; gluteus maximus mobilization; a sliding muscle graft procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989267"}
{"pmid": "20989268", "title": "Anaphylaxis-like reactions produced by ascaris extracts; the mechanism of the shock induced in dogs.", "content": "Anaphylaxis-like reactions produced by ascaris extracts; the mechanism of the shock induced in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989268"}
{"pmid": "20989269", "title": "Struma lymphomatosa.", "content": "Struma lymphomatosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989269"}
{"pmid": "20989310", "title": "Primary malignant disease of the stomach.", "content": "Primary malignant disease of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989310"}
{"pmid": "20989320", "title": "Non-specific genital infections; the isolation of organisms of the pleuropneumonia group from the genital tract and their relation to the gonococcus.", "content": "Non-specific genital infections; the isolation of organisms of the pleuropneumonia group from the genital tract and their relation to the gonococcus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989320"}
{"pmid": "20989304", "title": "Amino acids in surgery.", "content": "Amino acids in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989304"}
{"pmid": "20989306", "title": "Symposium on use of penicillin; presented at Guild Meeting, Milwaukee, Wisconsin, March 28, 1945.", "content": "Symposium on use of penicillin; presented at Guild Meeting, Milwaukee, Wisconsin, March 28, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989306"}
{"pmid": "20989312", "title": "The artificial pupil in the restoration of vision.", "content": "The artificial pupil in the restoration of vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989312"}
{"pmid": "20989308", "title": "Some obstetrical and gynecological problems.", "content": "Some obstetrical and gynecological problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989308"}
{"pmid": "20989307", "title": "Rehabilitation in the Navy.", "content": "Rehabilitation in the Navy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989307"}
{"pmid": "20989305", "title": "Exaggeration phenomena.", "content": "Exaggeration phenomena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989305"}
{"pmid": "20989311", "title": "Mexico and the Latin Americas.", "content": "Mexico and the Latin Americas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989311"}
{"pmid": "20989309", "title": "Herniation of subfascial fat as a cause of low back pain; results of surgical treatment in thirty-one cases.", "content": "Herniation of subfascial fat as a cause of low back pain; results of surgical treatment in thirty-one cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989309"}
{"pmid": "20989321", "title": "Venereal disease in India.", "content": "Venereal disease in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989321"}
{"pmid": "20989323", "title": "The treatment of early syphilis by intensive and semi-intensive arsenotherapy.", "content": "The treatment of early syphilis by intensive and semi-intensive arsenotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989323"}
{"pmid": "20989322", "title": "Venereal disease in British West Africa.", "content": "Venereal disease in British West Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989322"}
{"pmid": "20989324", "title": "Stricture formation following sulphonamide therapy of gonorrhoea.", "content": "Stricture formation following sulphonamide therapy of gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989324"}
{"pmid": "20989325", "title": "Leaflets on the treatment of venereal diseases of the early nineteenth century.", "content": "Leaflets on the treatment of venereal diseases of the early nineteenth century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989325"}
{"pmid": "20989316", "title": "The responsibility of the surgeon in the preservation of human fertility.", "content": "The responsibility of the surgeon in the preservation of human fertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989316"}
{"pmid": "20989326", "title": "Penicillin therapy of early syphilis.", "content": "Penicillin therapy of early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989326"}
{"pmid": "20989313", "title": "Ligation treatment for varicose veins; an estimate of the present status of this method.", "content": "Ligation treatment for varicose veins; an estimate of the present status of this method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989313"}
{"pmid": "20989314", "title": "Evaluation of methods of study of peripheral vascular circulation.", "content": "Evaluation of methods of study of peripheral vascular circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989314"}
{"pmid": "20989315", "title": "Observations on the eyelids.", "content": "Observations on the eyelids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989315"}
{"pmid": "20989317", "title": "Occupational therapy in the rehabilitation of surgical cases.", "content": "Occupational therapy in the rehabilitation of surgical cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989317"}
{"pmid": "20989330", "title": "The burst size distribution in the growth of bacterial viruses (bacteriophages).", "content": "The burst size distribution in the growth of bacterial viruses (bacteriophages).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989330"}
{"pmid": "20989331", "title": "Effects of specific antisera on the growth of bacterial viruses (bacteriophages).", "content": "Effects of specific antisera on the growth of bacterial viruses (bacteriophages).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989331"}
{"pmid": "20989318", "title": "The classic cesarean section.", "content": "The classic cesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989318"}
{"pmid": "20989332", "title": "Interference between bacterial viruses; the mutual exclusion effect and the depressor effect.", "content": "Interference between bacterial viruses; the mutual exclusion effect and the depressor effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989332"}
{"pmid": "20989333", "title": "Observations of hemolytic Escherichia coli on blood agar and eosin methylene blue agar.", "content": "Observations of hemolytic Escherichia coli on blood agar and eosin methylene blue agar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989333"}
{"pmid": "20989334", "title": "Further studies on the effects of spleen extract on bacteria.", "content": "Further studies on the effects of spleen extract on bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989334"}
{"pmid": "20989335", "title": "Penicillin assay and its control chart analysis.", "content": "Penicillin assay and its control chart analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989335"}
{"pmid": "20989336", "title": "The significance of sodium chloride in studies of staphylococci.", "content": "The significance of sodium chloride in studies of staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989336"}
{"pmid": "20989337", "title": "Effect of penicillin on infection of guinea pigs with Corynebacterium diphtheriae.", "content": "Effect of penicillin on infection of guinea pigs with Corynebacterium diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989337"}
{"pmid": "20989338", "title": "The occurrence of Bacillus botulinus, types A and B, in accidental wounds.", "content": "The occurrence of Bacillus botulinus, types A and B, in accidental wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989338"}
{"pmid": "20989339", "title": "Transformation of the Streptococcus lactis R factor to folic acid by resting cell suspensions of enterococci.", "content": "Transformation of the Streptococcus lactis R factor to folic acid by resting cell suspensions of enterococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989339"}
{"pmid": "20989340", "title": "Human food poisoning due to growth of Clostridium perfringens (C. welchii) in freshly cooked chicken.", "content": "Human food poisoning due to growth of Clostridium perfringens (C. welchii) in freshly cooked chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989340"}
{"pmid": "20989341", "title": "Lygus bug injury of lima bean in California.", "content": "Lygus bug injury of lima bean in California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989341"}
{"pmid": "20989342", "title": "Bud, blossom, and pod drop of canning string beans reduced by plant hormones.", "content": "Bud, blossom, and pod drop of canning string beans reduced by plant hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989342"}
{"pmid": "20989344", "title": "Response of spring barley varieties to floral loose smut inoculation.", "content": "Response of spring barley varieties to floral loose smut inoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989344"}
{"pmid": "20989345", "title": "Seed transmission of bacterial blight of sugar beet.", "content": "Seed transmission of bacterial blight of sugar beet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989345"}
{"pmid": "20989343", "title": "Lespedeza anthracnose.", "content": "Lespedeza anthracnose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989343"}
{"pmid": "20989346", "title": "Effect of mineral nutrition on the vigor and susceptibility to blight of old Japanese chestnut trees.", "content": "Effect of mineral nutrition on the vigor and susceptibility to blight of old Japanese chestnut trees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989346"}
{"pmid": "20989347", "title": "Rust and phosphorus distribution in wheat leaves.", "content": "Rust and phosphorus distribution in wheat leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989347"}
{"pmid": "20989417", "title": "Insulin-induced rumplessness of chickens; the relationship of dosage and of developmental stage at time of injection to response.", "content": "Insulin-induced rumplessness of chickens; the relationship of dosage and of developmental stage at time of injection to response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989417"}
{"pmid": "20989418", "title": "Gustatory thresholds for sucrose and electrolytes for the cockroach, Periplaneta americana (Linn.).", "content": "Gustatory thresholds for sucrose and electrolytes for the cockroach, Periplaneta americana (Linn.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989418"}
{"pmid": "20989419", "title": "Experiments on the formed inclusions of the amphibian egg; formative effects of hydration and dehydration on lipid bodies.", "content": "Experiments on the formed inclusions of the amphibian egg; formative effects of hydration and dehydration on lipid bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989419"}
{"pmid": "20989420", "title": "The influence of the peripheral field on the development of the mesencephalic V nucleus in amblystoma.", "content": "The influence of the peripheral field on the development of the mesencephalic V nucleus in amblystoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989420"}
{"pmid": "20989430", "title": "The influence of phytic acid on the absorption of calcium and phosphorus; in dogs.", "content": "The influence of phytic acid on the absorption of calcium and phosphorus; in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989430"}
{"pmid": "20989431", "title": "Studies on cholinesterase; the selective inhibition of pseudo-cholinesterase in vivo.", "content": "Studies on cholinesterase; the selective inhibition of pseudo-cholinesterase in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989431"}
{"pmid": "20989434", "title": "The metabolism of sulphonamides.", "content": "The metabolism of sulphonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989434"}
{"pmid": "20989435", "title": "The metabolism of sulphonamides; the isolation and identification of 3-hydroxysulphanilamide as the oxidation product of sulphanilamide in the rabbit.", "content": "The metabolism of sulphonamides; the isolation and identification of 3-hydroxysulphanilamide as the oxidation product of sulphanilamide in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989435"}
{"pmid": "20989436", "title": "Studies in detoxication; the metabolism of veratraldehyde and veratric acid in the rabbit.", "content": "Studies in detoxication; the metabolism of veratraldehyde and veratric acid in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989436"}
{"pmid": "20989438", "title": "Yeast lactic dehydrogenase and cytochrome b2.", "content": "Yeast lactic dehydrogenase and cytochrome b2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989438"}
{"pmid": "20989444", "title": "The free amino group of gramicidin S.", "content": "The free amino group of gramicidin S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989444"}
{"pmid": "20989445", "title": "A note on the action of tannin upon tumour glycolysis.", "content": "A note on the action of tannin upon tumour glycolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989445"}
{"pmid": "20989447", "title": "The metabolism and functioning of vitamin-like compounds; a comparison of pantothenate metabolism by proliferating and by non-proliferating bacteria.", "content": "The metabolism and functioning of vitamin-like compounds; a comparison of pantothenate metabolism by proliferating and by non-proliferating bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989447"}
{"pmid": "20989451", "title": "The component acids of cow colostrum fat.", "content": "The component acids of cow colostrum fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989451"}
{"pmid": "20989452", "title": "The capsular substance of Bacillus anthracis.", "content": "The capsular substance of Bacillus anthracis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989452"}
{"pmid": "20989455", "title": "The capsular substance of Bacillus anthracis.", "content": "The capsular substance of Bacillus anthracis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989455"}
{"pmid": "20989456", "title": "The role of linoleic acid, alpha-tocopherol and other fat-soluble substances in the nutrition of an insect (Ephestia kuehniella Lep.).", "content": "The role of linoleic acid, alpha-tocopherol and other fat-soluble substances in the nutrition of an insect (Ephestia kuehniella Lep.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989456"}
{"pmid": "20989457", "title": "Further studies of the Van den Bergh reaction in haemolytic jaundice.", "content": "Further studies of the Van den Bergh reaction in haemolytic jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989457"}
{"pmid": "20989458", "title": "The metabolism of marfanil (homosulphanilamide) in the rabbit.", "content": "The metabolism of marfanil (homosulphanilamide) in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989458"}
{"pmid": "20989459", "title": "Some observations on the composition of defatted fowl plasma.", "content": "Some observations on the composition of defatted fowl plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989459"}
{"pmid": "20989460", "title": "Serum albumin and globulin levels in premature infants.", "content": "Serum albumin and globulin levels in premature infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989460"}
{"pmid": "20989461", "title": "Direct crystallization of lysozyme from egg white and some crystalline salts of lysozyme.", "content": "Direct crystallization of lysozyme from egg white and some crystalline salts of lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989461"}
{"pmid": "20989462", "title": "Behavior of dextrins towards taka-diastase.", "content": "Behavior of dextrins towards taka-diastase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989462"}
{"pmid": "20989463", "title": "Structural analogues antagonistic to thyroxine.", "content": "Structural analogues antagonistic to thyroxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989463"}
{"pmid": "20989464", "title": "Synthesis of imidazolidone aliphatic acids.", "content": "Synthesis of imidazolidone aliphatic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989464"}
{"pmid": "20989465", "title": "Relationship of thiol structures to reaction with antibiotics.", "content": "Relationship of thiol structures to reaction with antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989465"}
{"pmid": "20989466", "title": "2-Keto-D-gluconic acid in the polysaccharide of Irish moss.", "content": "2-Keto-D-gluconic acid in the polysaccharide of Irish moss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989466"}
{"pmid": "20989467", "title": "The in vivo inactivation by cyanide of brain cytochrome oxidase and its effect on glycolysis and on the high energy phosphorus compounds in brain.", "content": "The in vivo inactivation by cyanide of brain cytochrome oxidase and its effect on glycolysis and on the high energy phosphorus compounds in brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989467"}
{"pmid": "20989468", "title": "Biochemical transformations as determined by competitive analogue-metabolite growth inhibitions; a transformation involving phenylalanine.", "content": "Biochemical transformations as determined by competitive analogue-metabolite growth inhibitions; a transformation involving phenylalanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989468"}
{"pmid": "20989469", "title": "The purification of toxin from Clostridium botulinum type A.", "content": "The purification of toxin from Clostridium botulinum type A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989469"}
{"pmid": "20989470", "title": "Preliminary studies on the production of alpha-ketoglutaric acid by Pseudomonas fluorescens.", "content": "Preliminary studies on the production of alpha-ketoglutaric acid by Pseudomonas fluorescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989470"}
{"pmid": "20989471", "title": "Biological conversion of inositol into glucose.", "content": "Biological conversion of inositol into glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989471"}
{"pmid": "20989472", "title": "Biophysical studies of blood plasma proteins; the pepsin digestion and recovery of human gamma-globulin.", "content": "Biophysical studies of blood plasma proteins; the pepsin digestion and recovery of human gamma-globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989472"}
{"pmid": "20989473", "title": "Biophysical studies of blood plasma proteins; recovery of gamma-globulin from human blood protein mixtures.", "content": "Biophysical studies of blood plasma proteins; recovery of gamma-globulin from human blood protein mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989473"}
{"pmid": "20989474", "title": "The biochemistry of the malaria parasite; mechanism of pyruvate oxidation in the malaria parasite.", "content": "The biochemistry of the malaria parasite; mechanism of pyruvate oxidation in the malaria parasite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989474"}
{"pmid": "20989475", "title": "The biochemistry of the malaria parasite; studies on the nitrogen metabolism of the malaria parasite.", "content": "The biochemistry of the malaria parasite; studies on the nitrogen metabolism of the malaria parasite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989475"}
{"pmid": "20989476", "title": "Amino acid composition of seed globulins.", "content": "Amino acid composition of seed globulins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989476"}
{"pmid": "20989477", "title": "Conversion of sulfide sulfur to cystine sulfur in the rat, with use of radioactive sulfur.", "content": "Conversion of sulfide sulfur to cystine sulfur in the rat, with use of radioactive sulfur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989477"}
{"pmid": "20989478", "title": "The influence of certain substances on the antibiotic activity of streptomycin in vitro; the action of some carbonyl reagents on streptomycin.", "content": "The influence of certain substances on the antibiotic activity of streptomycin in vitro; the action of some carbonyl reagents on streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989478"}
{"pmid": "20989479", "title": "A colorimetric method for the determination of penicillin.", "content": "A colorimetric method for the determination of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989479"}
{"pmid": "20989480", "title": "A rapid micromethod for the fluorometric determination of penicillin.", "content": "A rapid micromethod for the fluorometric determination of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989480"}
{"pmid": "20989481", "title": "Amino acids in the production of granulocytes in rats.", "content": "Amino acids in the production of granulocytes in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989481"}
{"pmid": "20989482", "title": "Free tryptophane in blood and urine.", "content": "Free tryptophane in blood and urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989482"}
{"pmid": "20989483", "title": "The solubility curve and the purity of insulin.", "content": "The solubility curve and the purity of insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989483"}
{"pmid": "20989484", "title": "The action of ribonuclease on the succinoxidase system.", "content": "The action of ribonuclease on the succinoxidase system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989484"}
{"pmid": "20989485", "title": "The effects of the volatile aldehydes formed on the accuracy of the manometric ninhydrin-carbon dioxide method in analysis of certain alpha-amino acids.", "content": "The effects of the volatile aldehydes formed on the accuracy of the manometric ninhydrin-carbon dioxide method in analysis of certain alpha-amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989485"}
{"pmid": "20989486", "title": "Oxygen poisoning; the effect of oxygen at eight atmospheres upon the oxygen consumption of the intact mouse.", "content": "Oxygen poisoning; the effect of oxygen at eight atmospheres upon the oxygen consumption of the intact mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989486"}
{"pmid": "20989487", "title": "Oxygen poisoning; the relation between inactivation of enzymes by oxygen and essential sulfhydryl groups.", "content": "Oxygen poisoning; the relation between inactivation of enzymes by oxygen and essential sulfhydryl groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989487"}
{"pmid": "20989488", "title": "An enzyme in animal tissues capable of hydrolysing the phosphorus-fluorine bond of alkyl fluorophosphates.", "content": "An enzyme in animal tissues capable of hydrolysing the phosphorus-fluorine bond of alkyl fluorophosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989488"}
{"pmid": "20989489", "title": "A quantitative study of the products of fatty acid oxidation in liver suspensions.", "content": "A quantitative study of the products of fatty acid oxidation in liver suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989489"}
{"pmid": "20989490", "title": "The relation of the diet to the composition of tissue phospholipides; liver lecithin as related to the choline and fat content of the diet.", "content": "The relation of the diet to the composition of tissue phospholipides; liver lecithin as related to the choline and fat content of the diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989490"}
{"pmid": "20989491", "title": "Relation of fasting ketosis to the protein of the preceding diet.", "content": "Relation of fasting ketosis to the protein of the preceding diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989491"}
{"pmid": "20989492", "title": "A method for the rapid determination of alkaline phosphates with five cubic millimeters of serum.", "content": "A method for the rapid determination of alkaline phosphates with five cubic millimeters of serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989492"}
{"pmid": "20989493", "title": "A microdetermination of glutamic acid and its application to protein analysis.", "content": "A microdetermination of glutamic acid and its application to protein analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989493"}
{"pmid": "20989494", "title": "The immune proteins of bovine colostrum and plasma.", "content": "The immune proteins of bovine colostrum and plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989494"}
{"pmid": "20989495", "title": "Amino acid and carbohydrate analyses of some immune proteins.", "content": "Amino acid and carbohydrate analyses of some immune proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989495"}
{"pmid": "20989496", "title": "The absorption spectra of immune proteins.", "content": "The absorption spectra of immune proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989496"}
{"pmid": "20989497", "title": "Experimentally induced changes in the prothrombin level of the blood; prothrombin concentration of new-born pups of a mother given dicumarol before parturition.", "content": "Experimentally induced changes in the prothrombin level of the blood; prothrombin concentration of new-born pups of a mother given dicumarol before parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989497"}
{"pmid": "20989498", "title": "A tracer study of iron metabolism with radioactive iron; methods: absorption and excretion of iron.", "content": "A tracer study of iron metabolism with radioactive iron; methods: absorption and excretion of iron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989498"}
{"pmid": "20989499", "title": "A tracer study of iron metabolism with radioactive iron; internal metabolism.", "content": "A tracer study of iron metabolism with radioactive iron; internal metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989499"}
{"pmid": "20989500", "title": "Further studies of organic factors required for prevention of anemia in chicks.", "content": "Further studies of organic factors required for prevention of anemia in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989500"}
{"pmid": "20989501", "title": "The occurrence of hydroxypyruvic acid in biological systems.", "content": "The occurrence of hydroxypyruvic acid in biological systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989501"}
{"pmid": "20989502", "title": "A study of beta-hydroxy-alpha-keto acids.", "content": "A study of beta-hydroxy-alpha-keto acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989502"}
{"pmid": "20989503", "title": "On oxidative decarboxylations with periodic acid.", "content": "On oxidative decarboxylations with periodic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989503"}
{"pmid": "20989504", "title": "Degradation of the bile acid side chain.", "content": "Degradation of the bile acid side chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989504"}
{"pmid": "20989505", "title": "The fixation of carbon dioxide in oxalacetate by pigeon liver.", "content": "The fixation of carbon dioxide in oxalacetate by pigeon liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989505"}
{"pmid": "20989506", "title": "Identification of linoleic and linolenic acids of beef tallow.", "content": "Identification of linoleic and linolenic acids of beef tallow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989506"}
{"pmid": "20989507", "title": "Biological acetylation of natural amino acids.", "content": "Biological acetylation of natural amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989507"}
{"pmid": "20989508", "title": "The antagonism of sulfonamides by pteroylglutamic acid and related compounds.", "content": "The antagonism of sulfonamides by pteroylglutamic acid and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989508"}
{"pmid": "20989509", "title": "A study of the paracapillary nutrition canals and their possible sympathetic innervation.", "content": "A study of the paracapillary nutrition canals and their possible sympathetic innervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989509"}
{"pmid": "20989510", "title": "Quick decalcination of teeth.", "content": "Quick decalcination of teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989510"}
{"pmid": "20989511", "title": "Leukoplakia oris.", "content": "Leukoplakia oris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989511"}
{"pmid": "20989512", "title": "What rôle do Treponema vincenti play in certain diseases of the gingiva?", "content": "What rôle do Treponema vincenti play in certain diseases of the gingiva?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989512"}
{"pmid": "20989513", "title": "On the rôle of mucin in the pathogenesis of caries.", "content": "On the rôle of mucin in the pathogenesis of caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989513"}
{"pmid": "20989515", "title": "The construction of radium applicators.", "content": "The construction of radium applicators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989515"}
{"pmid": "20989514", "title": "Studies in incisor pigmentation in relation to liver-iron and blood-picture in the white rat; gastrectomy as the cause of depigmentation of incisors of rats.", "content": "Studies in incisor pigmentation in relation to liver-iron and blood-picture in the white rat; gastrectomy as the cause of depigmentation of incisors of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989514"}
{"pmid": "20989516", "title": "Interesting use of plastic teeth.", "content": "Interesting use of plastic teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989516"}
{"pmid": "20989517", "title": "Maxillo facial injuries in children and their sequelae.", "content": "Maxillo facial injuries in children and their sequelae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989517"}
{"pmid": "20989518", "title": "Penicillin prescribing for dentists.", "content": "Penicillin prescribing for dentists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989518"}
{"pmid": "20989519", "title": "Some nineteenth-century incidents.", "content": "Some nineteenth-century incidents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989519"}
{"pmid": "20989521", "title": "Dentistry amongst the labour classes.", "content": "Dentistry amongst the labour classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989521"}
{"pmid": "20989532", "title": "SYMPOSIUM on problems of aviation dentistry.", "content": "SYMPOSIUM on problems of aviation dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989532"}
{"pmid": "20989533", "title": "Mouth cancer and the dentist.", "content": "Mouth cancer and the dentist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989533"}
{"pmid": "20989534", "title": "The psychosomatic aspects of dental problems.", "content": "The psychosomatic aspects of dental problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989534"}
{"pmid": "20989535", "title": "Dental education and dental personnel.", "content": "Dental education and dental personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989535"}
{"pmid": "20989537", "title": "Indictment of contaminated amalgam.", "content": "Indictment of contaminated amalgam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989537"}
{"pmid": "20989536", "title": "The dental condition of Japanese-held American prisoners of war.", "content": "The dental condition of Japanese-held American prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989536"}
{"pmid": "20989520", "title": "Impacted lower third molar and its removal.", "content": "Impacted lower third molar and its removal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989520"}
{"pmid": "20989538", "title": "Surplus equipment for the veteran dentist.", "content": "Surplus equipment for the veteran dentist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989538"}
{"pmid": "20989539", "title": "FEE schedule.", "content": "FEE schedule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989539"}
{"pmid": "20989540", "title": "A resume of the mandibular injection.", "content": "A resume of the mandibular injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989540"}
{"pmid": "20989541", "title": "Miscellaneous uses of local anesthesia in general dentistry.", "content": "Miscellaneous uses of local anesthesia in general dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989541"}
{"pmid": "20989542", "title": "Intra-osseous local anesthesia.", "content": "Intra-osseous local anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989542"}
{"pmid": "20989543", "title": "Anesthesia of the mandible after a tuberosity injection.", "content": "Anesthesia of the mandible after a tuberosity injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989543"}
{"pmid": "20989613", "title": "Nutritional problems of starvation and rehabilitation.", "content": "Nutritional problems of starvation and rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989613"}
{"pmid": "20989615", "title": "Relationships between dry weight, protein, and vitamins in leaves of cereals.", "content": "Relationships between dry weight, protein, and vitamins in leaves of cereals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989615"}
{"pmid": "20989616", "title": "Prevalence of Clostridium botulinum in soils of central New York State.", "content": "Prevalence of Clostridium botulinum in soils of central New York State.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989616"}
{"pmid": "20989623", "title": "The effect of variations in the level of dietary calcium upon the growth of young rats receiving atabrine.", "content": "The effect of variations in the level of dietary calcium upon the growth of young rats receiving atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989623"}
{"pmid": "20989624", "title": "Phosphorus metabolism of preschool children.", "content": "Phosphorus metabolism of preschool children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989624"}
{"pmid": "20989618", "title": "Factors affecting some physicochemical properties of starch.", "content": "Factors affecting some physicochemical properties of starch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989618"}
{"pmid": "20989614", "title": "Determination of surface area of dehydrated egg powder.", "content": "Determination of surface area of dehydrated egg powder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989614"}
{"pmid": "20989619", "title": "Pasteurization of liquid-egg products; bacteria reduction in liquid whole egg and improvement in keeping quality.", "content": "Pasteurization of liquid-egg products; bacteria reduction in liquid whole egg and improvement in keeping quality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989619"}
{"pmid": "20989625", "title": "Nitrogen metabolism of preschool children.", "content": "Nitrogen metabolism of preschool children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989625"}
{"pmid": "20989626", "title": "The comparative growth-promoting value of the proteins of wheat germ, corn germ, and of some other protein foods of plant and animal origin.", "content": "The comparative growth-promoting value of the proteins of wheat germ, corn germ, and of some other protein foods of plant and animal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989626"}
{"pmid": "20989627", "title": "A study of pyridoxine and pantothenic acid deficiencies in the monkey (Macaca mulatta).", "content": "A study of pyridoxine and pantothenic acid deficiencies in the monkey (Macaca mulatta).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989627"}
{"pmid": "20989628", "title": "Covitamin studies; the interrelation of alpha-tocopherol and essential unsaturated fat acids.", "content": "Covitamin studies; the interrelation of alpha-tocopherol and essential unsaturated fat acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989628"}
{"pmid": "20989617", "title": "Relationships between fractions of phosphorus in soil and growth of cereals.", "content": "Relationships between fractions of phosphorus in soil and growth of cereals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989617"}
{"pmid": "20989629", "title": "Biological value of proteins in relation to the essential amino acids which they contain; comparison of proteins with mixtures of the amino acids.", "content": "Biological value of proteins in relation to the essential amino acids which they contain; comparison of proteins with mixtures of the amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989629"}
{"pmid": "20989630", "title": "Studies on the comparative nutritive value of fats; growth rate with restricted calories and on injection of the growth hormone.", "content": "Studies on the comparative nutritive value of fats; growth rate with restricted calories and on injection of the growth hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989630"}
{"pmid": "20989621", "title": "Some cooking qualities of homogenized milk; white sauces.", "content": "Some cooking qualities of homogenized milk; white sauces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989621"}
{"pmid": "20989631", "title": "Studies on the comparative nutritive value of fats; the failure of ether extraction to lower the nutritive value of skimmed milk powder in diets containing various vegetable fats.", "content": "Studies on the comparative nutritive value of fats; the failure of ether extraction to lower the nutritive value of skimmed milk powder in diets containing various vegetable fats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989631"}
{"pmid": "20989620", "title": "Pasteurization of liquid-egg products; effect of heat treatments on appearance and viscosity.", "content": "Pasteurization of liquid-egg products; effect of heat treatments on appearance and viscosity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989620"}
{"pmid": "20989632", "title": "Thiamine, riboflavin, nicotinic acid, pantothenic acid and ascorbic acid content of restaurant foods.", "content": "Thiamine, riboflavin, nicotinic acid, pantothenic acid and ascorbic acid content of restaurant foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989632"}
{"pmid": "20989633", "title": "The comparative value of certain dietary proteins for hemopoiesis in the rat.", "content": "The comparative value of certain dietary proteins for hemopoiesis in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989633"}
{"pmid": "20989622", "title": "Prevention of mold in kettled blueberries in No. 10 cans.", "content": "Prevention of mold in kettled blueberries in No. 10 cans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989622"}
{"pmid": "20989655", "title": "Diet in uncontrolled diabetes preceding acute neuropathy.", "content": "Diet in uncontrolled diabetes preceding acute neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989655"}
{"pmid": "20989656", "title": "Fasting blood sugar vs. postprandial blood sugar as observed in normal individuals, medical (non-diabetic) patients, and patients with diabetes; special references to; plain, protamine zinc and globin insulins, compatible hyperglycemia and arteriosclerosis.", "content": "Fasting blood sugar vs. postprandial blood sugar as observed in normal individuals, medical (non-diabetic) patients, and patients with diabetes; special references to; plain, protamine zinc and globin insulins, compatible hyperglycemia and arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989656"}
{"pmid": "20989657", "title": "Sudden and drastic changes of the carbohydrate tolerance in severe insulin-treated diabetes.", "content": "Sudden and drastic changes of the carbohydrate tolerance in severe insulin-treated diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989657"}
{"pmid": "20989658", "title": "The control of diarrhea by tomato pomace.", "content": "The control of diarrhea by tomato pomace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989658"}
{"pmid": "20989659", "title": "Experiences in non-specific diarrheal conditions in the European Theater of Operations.", "content": "Experiences in non-specific diarrheal conditions in the European Theater of Operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989659"}
{"pmid": "20989678", "title": "Geriatrics.", "content": "Geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989678"}
{"pmid": "20989679", "title": "A study of the pathogenesis of chronic pulmonary disease (bronchiectasis) of old rats.", "content": "A study of the pathogenesis of chronic pulmonary disease (bronchiectasis) of old rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989679"}
{"pmid": "20989680", "title": "Geriatric urology.", "content": "Geriatric urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989680"}
{"pmid": "20989673", "title": "Cerebral arteriosclerosis, with small, commonly unrecognized apoplexies.", "content": "Cerebral arteriosclerosis, with small, commonly unrecognized apoplexies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989673"}
{"pmid": "20989681", "title": "The factor of age in determining the toxicity of certain poisons.", "content": "The factor of age in determining the toxicity of certain poisons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989681"}
{"pmid": "20989682", "title": "The effects of estrogens on the senile skin.", "content": "The effects of estrogens on the senile skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989682"}
{"pmid": "20989674", "title": "Peptic ulcer in old age.", "content": "Peptic ulcer in old age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989674"}
{"pmid": "20989683", "title": "The influence of the aging process on the distribution of certain components of the blood and the gastrocnemius muscle of the albino rat.", "content": "The influence of the aging process on the distribution of certain components of the blood and the gastrocnemius muscle of the albino rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989683"}
{"pmid": "20989684", "title": "Comparative chronologic age in man and other mammals.", "content": "Comparative chronologic age in man and other mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989684"}
{"pmid": "20989675", "title": "Endocrine aspects of senescence.", "content": "Endocrine aspects of senescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989675"}
{"pmid": "20989685", "title": "German health insurance; the evolution of a bureaucracy.", "content": "German health insurance; the evolution of a bureaucracy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989685"}
{"pmid": "20989686", "title": "DDT for household use.", "content": "DDT for household use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989686"}
{"pmid": "20989676", "title": "Kidney function tests in aged males.", "content": "Kidney function tests in aged males.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989676"}
{"pmid": "20989677", "title": "Proctologic problems in the aged.", "content": "Proctologic problems in the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989677"}
{"pmid": "20989692", "title": "The war and British medical libraries.", "content": "The war and British medical libraries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989692"}
{"pmid": "20989693", "title": "The exchange.", "content": "The exchange.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989693"}
{"pmid": "20989694", "title": "The founding of the Yale Medical School.", "content": "The founding of the Yale Medical School.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989694"}
{"pmid": "20989695", "title": "Libraries and librarians.", "content": "Libraries and librarians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989695"}
{"pmid": "20989696", "title": "History of the Yale Medical Libraries.", "content": "History of the Yale Medical Libraries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989696"}
{"pmid": "20989697", "title": "Interlibrary loans.", "content": "Interlibrary loans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989697"}
{"pmid": "20989698", "title": "Interlibrary loans, College of Physicians of Philadelphia.", "content": "Interlibrary loans, College of Physicians of Philadelphia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989698"}
{"pmid": "20989699", "title": "Interlibrary loans.", "content": "Interlibrary loans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989699"}
{"pmid": "20989700", "title": "Interlibrary loans; the case for the borrowing library.", "content": "Interlibrary loans; the case for the borrowing library.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989700"}
{"pmid": "20989701", "title": "Need for the adoption of an interlibrary loan code.", "content": "Need for the adoption of an interlibrary loan code.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989701"}
{"pmid": "20989702", "title": "Interlibrary lending policies; discussion.", "content": "Interlibrary lending policies; discussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989702"}
{"pmid": "20989703", "title": "Some influential books in the history of dentistry.", "content": "Some influential books in the history of dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989703"}
{"pmid": "20989704", "title": "Army Medical Library cataloging.", "content": "Army Medical Library cataloging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989704"}
{"pmid": "20989705", "title": "The acquisition program of the Army Medical Library.", "content": "The acquisition program of the Army Medical Library.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989705"}
{"pmid": "20989706", "title": "Serving the professional public.", "content": "Serving the professional public.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989706"}
{"pmid": "20989707", "title": "Reorganization of the Army Medical Library.", "content": "Reorganization of the Army Medical Library.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989707"}
{"pmid": "20989708", "title": "The Cleveland restoration [of rare books].", "content": "The Cleveland restoration [of rare books].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989708"}
{"pmid": "20989709", "title": "A forward glance [the Army Medical Library].", "content": "A forward glance [the Army Medical Library].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989709"}
{"pmid": "20989715", "title": "GOOD hospital architect.", "content": "GOOD hospital architect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989715"}
{"pmid": "20989716", "title": "Engineering in hospitals; main and satellite kitchens.", "content": "Engineering in hospitals; main and satellite kitchens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989716"}
{"pmid": "20989714", "title": "FEEDING 40,000 patients and staff; how the London County Council solves the problem.", "content": "FEEDING 40,000 patients and staff; how the London County Council solves the problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989714"}
{"pmid": "20989717", "title": "ST. BARTHOLOMEW'S Hospital.", "content": "ST. BARTHOLOMEW'S Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989717"}
{"pmid": "20989718", "title": "Common cold in industry.", "content": "Common cold in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989718"}
{"pmid": "20989712", "title": "The dawn of experimental science.", "content": "The dawn of experimental science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989712"}
{"pmid": "20989719", "title": "WHAT can the hospital do to bar infection from the nursery?", "content": "WHAT can the hospital do to bar infection from the nursery?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989719"}
{"pmid": "20989710", "title": "Wanted, a history of research.", "content": "Wanted, a history of research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989710"}
{"pmid": "20989713", "title": "The rise of modern research.", "content": "The rise of modern research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989713"}
{"pmid": "20989722", "title": "$100,000,000 TEXAS medical center construction gets under way.", "content": "$100,000,000 TEXAS medical center construction gets under way.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989722"}
{"pmid": "20989723", "title": "HOSPITAL administration in France.", "content": "HOSPITAL administration in France.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989723"}
{"pmid": "20989720", "title": "NEW YORK State hospitals ponder nurse shortages, health plans.", "content": "NEW YORK State hospitals ponder nurse shortages, health plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989720"}
{"pmid": "20989721", "title": "HOW shall hospitals accommodate physicians returning from war?", "content": "HOW shall hospitals accommodate physicians returning from war?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989721"}
{"pmid": "20989711", "title": "The beginnings of research.", "content": "The beginnings of research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989711"}
{"pmid": "20989724", "title": "Unofficial post-mortems; limits of legality.", "content": "Unofficial post-mortems; limits of legality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989724"}
{"pmid": "20989725", "title": "Hospital communications.", "content": "Hospital communications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989725"}
{"pmid": "20989726", "title": "Medical aid and rehabilitation for war invalids in Russia.", "content": "Medical aid and rehabilitation for war invalids in Russia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989726"}
{"pmid": "20989782", "title": "Emotional first aid stations in industry.", "content": "Emotional first aid stations in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989782"}
{"pmid": "20989783", "title": "Expansion of industrial hygiene programs in official agencies.", "content": "Expansion of industrial hygiene programs in official agencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989783"}
{"pmid": "20989784", "title": "Color vision in industry.", "content": "Color vision in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989784"}
{"pmid": "20989785", "title": "A practical surgical approach to the subclavian structures.", "content": "A practical surgical approach to the subclavian structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989785"}
{"pmid": "20989786", "title": "Tetryl exposure; analysis of 4 years of medical experience with tetryl.", "content": "Tetryl exposure; analysis of 4 years of medical experience with tetryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989786"}
{"pmid": "20989787", "title": "Personality programs in managerial groups.", "content": "Personality programs in managerial groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989787"}
{"pmid": "20989788", "title": "The present status of penicillin and the newer antibiotics.", "content": "The present status of penicillin and the newer antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989788"}
{"pmid": "20989789", "title": "Traumatic rupture of cardiac valve.", "content": "Traumatic rupture of cardiac valve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989789"}
{"pmid": "20989790", "title": "RAMAZZINI Society.", "content": "RAMAZZINI Society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989790"}
{"pmid": "20989791", "title": "Cardiovascular impairments in the industrial worker.", "content": "Cardiovascular impairments in the industrial worker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989791"}
{"pmid": "20989792", "title": "Silicosis, the most important of the pneumonoconioses.", "content": "Silicosis, the most important of the pneumonoconioses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989792"}
{"pmid": "20989793", "title": "Technical and social advances in industrial hygiene.", "content": "Technical and social advances in industrial hygiene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989793"}
{"pmid": "20989794", "title": "Total avulsion of the scalp; a review of the problem with presentation of a case of skin graft in which thrombin plasma fixation was used.", "content": "Total avulsion of the scalp; a review of the problem with presentation of a case of skin graft in which thrombin plasma fixation was used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989794"}
{"pmid": "20989796", "title": "The status of health education in industry.", "content": "The status of health education in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989796"}
{"pmid": "20989795", "title": "A new assistant for the plant physician; the industrial sanitationist.", "content": "A new assistant for the plant physician; the industrial sanitationist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989795"}
{"pmid": "20989797", "title": "Industrial and community health education.", "content": "Industrial and community health education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989797"}
{"pmid": "20989798", "title": "Health education in small industries.", "content": "Health education in small industries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989798"}
{"pmid": "20989799", "title": "Fort Greene industrial health plan.", "content": "Fort Greene industrial health plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989799"}
{"pmid": "20989800", "title": "Effects of industrial exposure to quinacrine hydrochloride.", "content": "Effects of industrial exposure to quinacrine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989800"}
{"pmid": "20989802", "title": "Behçet's disease as manifestation of a chronic septic condition connected with a constitutional disorder, with a report of four cases.", "content": "Behçet's disease as manifestation of a chronic septic condition connected with a constitutional disorder, with a report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989802"}
{"pmid": "20989803", "title": "The length and depth of sleep.", "content": "The length and depth of sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989803"}
{"pmid": "20989804", "title": "Leprosy of the nose in relation to the sexual apparatus.", "content": "Leprosy of the nose in relation to the sexual apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989804"}
{"pmid": "20989805", "title": "Contribution to the pathology of epidermophytosis.", "content": "Contribution to the pathology of epidermophytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989805"}
{"pmid": "20989806", "title": "Homologous serum hepatitis and infectious (epidemic) hepatitis; studies in volunteers bearing on immunological and other characteristics of the etiological agents.", "content": "Homologous serum hepatitis and infectious (epidemic) hepatitis; studies in volunteers bearing on immunological and other characteristics of the etiological agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989806"}
{"pmid": "20989807", "title": "Susceptibility to sulfadiazine of hemolytic streptococci recovered in Army camps.", "content": "Susceptibility to sulfadiazine of hemolytic streptococci recovered in Army camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989807"}
{"pmid": "20989809", "title": "A small visual comparator for the determination of plasma volume.", "content": "A small visual comparator for the determination of plasma volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989809"}
{"pmid": "20989808", "title": "The effect of an elevated temperature on the action of penicillin on viridans streptococci isolated from patients with subacute bacterial endocarditis.", "content": "The effect of an elevated temperature on the action of penicillin on viridans streptococci isolated from patients with subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989808"}
{"pmid": "20989801", "title": "The industrial hygiene services of the Illinois State Department of Public Health.", "content": "The industrial hygiene services of the Illinois State Department of Public Health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989801"}
{"pmid": "20989811", "title": "Treatment of migraine by intravenous histamine.", "content": "Treatment of migraine by intravenous histamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989811"}
{"pmid": "20989810", "title": "Electrocardiograms in rheumatic heart disease in children.", "content": "Electrocardiograms in rheumatic heart disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989810"}
{"pmid": "20989812", "title": "Hypothyroidism and mild myxedema from thiocyanate intoxication.", "content": "Hypothyroidism and mild myxedema from thiocyanate intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989812"}
{"pmid": "20989813", "title": "Congenital hemolytic jaundice in a Negro family.", "content": "Congenital hemolytic jaundice in a Negro family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989813"}
{"pmid": "20989814", "title": "Cretinism.", "content": "Cretinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989814"}
{"pmid": "20989815", "title": "The treatment of subacute bacterial endocarditis with antibiotics.", "content": "The treatment of subacute bacterial endocarditis with antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989815"}
{"pmid": "20989816", "title": "Treatment of barbiturate poisoning.", "content": "Treatment of barbiturate poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989816"}
{"pmid": "20989819", "title": "A classification of the different types of diabetes mellitus with a discussion of the diagnosis and treatment of each.", "content": "A classification of the different types of diabetes mellitus with a discussion of the diagnosis and treatment of each.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989819"}
{"pmid": "20989820", "title": "Sickle cell anaemia.", "content": "Sickle cell anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989820"}
{"pmid": "20989821", "title": "A case of chronic regional ileitis.", "content": "A case of chronic regional ileitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989821"}
{"pmid": "20989825", "title": "Typhus; experiences in the Central Mediterranean Force.", "content": "Typhus; experiences in the Central Mediterranean Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989825"}
{"pmid": "20989826", "title": "Duodenal ulceration; a gastroscopic study of the gastric mucosa and its surgical significance.", "content": "Duodenal ulceration; a gastroscopic study of the gastric mucosa and its surgical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989826"}
{"pmid": "20989827", "title": "Theory and nomenclature of the Rh types, subtypes, and genotypes.", "content": "Theory and nomenclature of the Rh types, subtypes, and genotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989827"}
{"pmid": "20989828", "title": "The Rh factor and hepatomegaly and splenomegaly in children and adolescents.", "content": "The Rh factor and hepatomegaly and splenomegaly in children and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989828"}
{"pmid": "20989829", "title": "Tuberculosis in service men.", "content": "Tuberculosis in service men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989829"}
{"pmid": "20989830", "title": "Amoeboma of the hepatic flexure.", "content": "Amoeboma of the hepatic flexure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989830"}
{"pmid": "20989831", "title": "Naples typhus epidemic.", "content": "Naples typhus epidemic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989831"}
{"pmid": "20989832", "title": "PREHABILITATION, rehabilitation, and revocation in the Army.", "content": "PREHABILITATION, rehabilitation, and revocation in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989832"}
{"pmid": "20989833", "title": "INDUSTRIAL resettlement of the neurotic.", "content": "INDUSTRIAL resettlement of the neurotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989833"}
{"pmid": "20989835", "title": "Typhus; experiences in the Central Mediterranean Force.", "content": "Typhus; experiences in the Central Mediterranean Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989835"}
{"pmid": "20989834", "title": "The evolution of clinical medicine as illustrated by the history of epilepsy.", "content": "The evolution of clinical medicine as illustrated by the history of epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989834"}
{"pmid": "20989836", "title": "Penicillin in treatment of severe diphtheria.", "content": "Penicillin in treatment of severe diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989836"}
{"pmid": "20989838", "title": "Undulant fever complicated by acute transient attacks of aphasia and during convalescence, by deafness, tinnitus, and paraesthesia.", "content": "Undulant fever complicated by acute transient attacks of aphasia and during convalescence, by deafness, tinnitus, and paraesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989838"}
{"pmid": "20989839", "title": "Carcinoma of the bladder associated with presence of a stone.", "content": "Carcinoma of the bladder associated with presence of a stone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989839"}
{"pmid": "20989837", "title": "A short survey of trilene in general practice.", "content": "A short survey of trilene in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989837"}
{"pmid": "20989840", "title": "Noma treated with penicillin.", "content": "Noma treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989840"}
{"pmid": "20989841", "title": "THE London Lock Hospital and its founder.", "content": "THE London Lock Hospital and its founder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989841"}
{"pmid": "20989843", "title": "What is clinical pathology?", "content": "What is clinical pathology?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989843"}
{"pmid": "20989842", "title": "Nutritional experiences in P.O.W. camps.", "content": "Nutritional experiences in P.O.W. camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989842"}
{"pmid": "20989844", "title": "Neurogenic ileus.", "content": "Neurogenic ileus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989844"}
{"pmid": "20989858", "title": "The use of residual hearing.", "content": "The use of residual hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989858"}
{"pmid": "20989859", "title": "Indications for specific types of psychiatric treatment.", "content": "Indications for specific types of psychiatric treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989859"}
{"pmid": "20989880", "title": "The reserve capacity of the human body and its scope in clinical medicine.", "content": "The reserve capacity of the human body and its scope in clinical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989880"}
{"pmid": "20989881", "title": "A case of rupture of the heart (with postmortem findings).", "content": "A case of rupture of the heart (with postmortem findings).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989881"}
{"pmid": "20989882", "title": "Development of cataract operation.", "content": "Development of cataract operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989882"}
{"pmid": "20989884", "title": "TREATMENT of communicable diseases.", "content": "TREATMENT of communicable diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989884"}
{"pmid": "20989883", "title": "Treatment of cholera.", "content": "Treatment of cholera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989883"}
{"pmid": "20989885", "title": "Public health figures that tell their own tale.", "content": "Public health figures that tell their own tale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989885"}
{"pmid": "20989900", "title": "OBSERVATIONS on malaria in the Far East.", "content": "OBSERVATIONS on malaria in the Far East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989900"}
{"pmid": "20989901", "title": "Preparation for marriage.", "content": "Preparation for marriage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989901"}
{"pmid": "20989902", "title": "Silicosis prevention.", "content": "Silicosis prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989902"}
{"pmid": "20989914", "title": "A case of acute intestinal obstruction caused by a dried peach.", "content": "A case of acute intestinal obstruction caused by a dried peach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989914"}
{"pmid": "20989915", "title": "A tour of the United States plastic surgery centers.", "content": "A tour of the United States plastic surgery centers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989915"}
{"pmid": "20989916", "title": "Penicillin in lung abscess.", "content": "Penicillin in lung abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989916"}
{"pmid": "20989917", "title": "Management of the diabetic.", "content": "Management of the diabetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989917"}
{"pmid": "20989918", "title": "Clinical application of sex hormone determinations.", "content": "Clinical application of sex hormone determinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989918"}
{"pmid": "20989919", "title": "New anti-histamine drugs in allergic diseases.", "content": "New anti-histamine drugs in allergic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989919"}
{"pmid": "20989920", "title": "Observations regarding war-time psychiatry.", "content": "Observations regarding war-time psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989920"}
{"pmid": "20989932", "title": "Causes of hyperglycaemia during operation.", "content": "Causes of hyperglycaemia during operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989932"}
{"pmid": "20989933", "title": "Pheniodol, a new dye for cholecystography.", "content": "Pheniodol, a new dye for cholecystography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989933"}
{"pmid": "20989934", "title": "Further cases of interest seen at the Wilson Radiological Department of the Erskine Hospital, Madura.", "content": "Further cases of interest seen at the Wilson Radiological Department of the Erskine Hospital, Madura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989934"}
{"pmid": "20989935", "title": "A clinical study of 20 cases of neuro-circulatory asthenia in civilian practice.", "content": "A clinical study of 20 cases of neuro-circulatory asthenia in civilian practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989935"}
{"pmid": "20989936", "title": "Somatic taeniasis (solium cysticercosis).", "content": "Somatic taeniasis (solium cysticercosis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989936"}
{"pmid": "20989937", "title": "Multiple deficiency following diet restricted for diarrhoea.", "content": "Multiple deficiency following diet restricted for diarrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989937"}
{"pmid": "20989938", "title": "Pulmonary amoebiasis.", "content": "Pulmonary amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989938"}
{"pmid": "20989939", "title": "Bovine tubercle bacilli and human extra-pulmonary tuberculous lesions in the Punjab.", "content": "Bovine tubercle bacilli and human extra-pulmonary tuberculous lesions in the Punjab.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989939"}
{"pmid": "20989940", "title": "Tropical eosinophilia; some further observations.", "content": "Tropical eosinophilia; some further observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989940"}
{"pmid": "20989941", "title": "Studies of ringworm; prophylactic measures.", "content": "Studies of ringworm; prophylactic measures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989941"}
{"pmid": "20989943", "title": "The life of liquid preparations of adrenaline under ordinary storage conditions in India.", "content": "The life of liquid preparations of adrenaline under ordinary storage conditions in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989943"}
{"pmid": "20989942", "title": "Culture medium from groundnut meal.", "content": "Culture medium from groundnut meal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989942"}
{"pmid": "20989944", "title": "Ocular manifestations in malaria.", "content": "Ocular manifestations in malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989944"}
{"pmid": "20989945", "title": "Myxoedema with ascites.", "content": "Myxoedema with ascites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989945"}
{"pmid": "20989946", "title": "Injury of the pancreas and its sequelae.", "content": "Injury of the pancreas and its sequelae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989946"}
{"pmid": "20989947", "title": "A case of madura foot treated with penicillin.", "content": "A case of madura foot treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989947"}
{"pmid": "20989948", "title": "Malarial infection in the newborn transmitted by mother.", "content": "Malarial infection in the newborn transmitted by mother.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989948"}
{"pmid": "20989949", "title": "A case of inguinal granuloma (granuloma inguinale tropicum) in Bengal.", "content": "A case of inguinal granuloma (granuloma inguinale tropicum) in Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989949"}
{"pmid": "20989950", "title": "Some recent advances in tropical medicine.", "content": "Some recent advances in tropical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989950"}
{"pmid": "20989951", "title": "Post-war medical resettlement.", "content": "Post-war medical resettlement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989951"}
{"pmid": "20989952", "title": "Vitamins in general practice.", "content": "Vitamins in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989952"}
{"pmid": "20989953", "title": "Mumps with subsequent suppuration (efficacy of M & B 693).", "content": "Mumps with subsequent suppuration (efficacy of M & B 693).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989953"}
{"pmid": "20989954", "title": "Doctors and disease in India.", "content": "Doctors and disease in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989954"}
{"pmid": "20989955", "title": "Scabies.", "content": "Scabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989955"}
{"pmid": "20989956", "title": "Immuno-therapy in tuberculosis.", "content": "Immuno-therapy in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989956"}
{"pmid": "20989957", "title": "Perforated peptic ulcer of the stomach and duodenum; based on a study of 116 cases.", "content": "Perforated peptic ulcer of the stomach and duodenum; based on a study of 116 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989957"}
{"pmid": "20989958", "title": "A case of Hodgkin's disease.", "content": "A case of Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989958"}
{"pmid": "20989959", "title": "Cancer of the lung.", "content": "Cancer of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989959"}
{"pmid": "20989960", "title": "Melanoma of the alveolus.", "content": "Melanoma of the alveolus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989960"}
{"pmid": "20989961", "title": "Liposarcoma of bone.", "content": "Liposarcoma of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989961"}
{"pmid": "20989962", "title": "Blood transfusion.", "content": "Blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989962"}
{"pmid": "20989963", "title": "The azygos lobe of the lung; accessory lobe of the azygos vein.", "content": "The azygos lobe of the lung; accessory lobe of the azygos vein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989963"}
{"pmid": "20989964", "title": "Hemangiomata and similar diseases of the bones, especially of the limbs.", "content": "Hemangiomata and similar diseases of the bones, especially of the limbs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989964"}
{"pmid": "20989965", "title": "Stabwound of the heart.", "content": "Stabwound of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989965"}
{"pmid": "20989966", "title": "Abdomino-perineal resection of the rectum.", "content": "Abdomino-perineal resection of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989966"}
{"pmid": "20989967", "title": "Cancer of the thyroid.", "content": "Cancer of the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989967"}
{"pmid": "20989968", "title": "Carcinoma of the base of the tongue.", "content": "Carcinoma of the base of the tongue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989968"}
{"pmid": "20989969", "title": "Rhabdomyosarcoma of the tongue.", "content": "Rhabdomyosarcoma of the tongue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989969"}
{"pmid": "20989970", "title": "Dendritic adenocarcinoma of sub-maxillary gland.", "content": "Dendritic adenocarcinoma of sub-maxillary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989970"}
{"pmid": "20989971", "title": "The nutritional aspects of ophthalmology.", "content": "The nutritional aspects of ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989971"}
{"pmid": "20989972", "title": "Studies in the mechanics of synovial joints; fundamental principles and diadochal movements.", "content": "Studies in the mechanics of synovial joints; fundamental principles and diadochal movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989972"}
{"pmid": "20989973", "title": "Ménière's syndrome.", "content": "Ménière's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989973"}
{"pmid": "20989974", "title": "A case of cerebral haematoma.", "content": "A case of cerebral haematoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989974"}
{"pmid": "20989975", "title": "Overweight; its prognostic significance in relation to hypertension and cardiovascular-renal diseases.", "content": "Overweight; its prognostic significance in relation to hypertension and cardiovascular-renal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989975"}
{"pmid": "20989976", "title": "Diverticula of the stomach.", "content": "Diverticula of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989976"}
{"pmid": "20989977", "title": "Human toxoplasmosis.", "content": "Human toxoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989977"}
{"pmid": "20989978", "title": "Preinvasive carcinoma of the cervix uteri.", "content": "Preinvasive carcinoma of the cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989978"}
{"pmid": "20989979", "title": "Chloroquine for treatment of acute attacks of vivax malaria.", "content": "Chloroquine for treatment of acute attacks of vivax malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989979"}
{"pmid": "20989980", "title": "Whooping cough; pertussis agglutinogen skin test after immunization with Hemophilus pertussis vaccine.", "content": "Whooping cough; pertussis agglutinogen skin test after immunization with Hemophilus pertussis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989980"}
{"pmid": "20989981", "title": "The transmission of penicillin to the previable fetus; its significance in prenatal syphilis.", "content": "The transmission of penicillin to the previable fetus; its significance in prenatal syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989981"}
{"pmid": "20989982", "title": "Fatal poisoning from motion sickness preventive.", "content": "Fatal poisoning from motion sickness preventive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989982"}
{"pmid": "20989984", "title": "GOVERNMENT medical care in Australia.", "content": "GOVERNMENT medical care in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989984"}
{"pmid": "20989983", "title": "Resolutions on establishment of Council on history of medicine.", "content": "Resolutions on establishment of Council on history of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989983"}
{"pmid": "20989985", "title": "Melanoma of the skin.", "content": "Melanoma of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989985"}
{"pmid": "20989986", "title": "Tropical medicine; classification.", "content": "Tropical medicine; classification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989986"}
{"pmid": "20989988", "title": "The American Women's Hospitals in Greece.", "content": "The American Women's Hospitals in Greece.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989988"}
{"pmid": "20989987", "title": "Report on the organization of cancer prevention clinics.", "content": "Report on the organization of cancer prevention clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989987"}
{"pmid": "20989989", "title": "WOMEN in medicine.", "content": "WOMEN in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989989"}
{"pmid": "20989990", "title": "Progress in abdominal surgery.", "content": "Progress in abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989990"}
{"pmid": "20989991", "title": "Pentothal sodium anesthesia in tonsillectomies.", "content": "Pentothal sodium anesthesia in tonsillectomies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989991"}
{"pmid": "20989992", "title": "Massive hemorrhage from the upper digestive tract.", "content": "Massive hemorrhage from the upper digestive tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989992"}
{"pmid": "20989993", "title": "The treatment of prostatism.", "content": "The treatment of prostatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989993"}
{"pmid": "20989994", "title": "Hypochromic anemia; treatment with molybdenum-iron complex.", "content": "Hypochromic anemia; treatment with molybdenum-iron complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989994"}
{"pmid": "20989995", "title": "A report on the use of 2,000 units of dried plasma under a State-wide health department program.", "content": "A report on the use of 2,000 units of dried plasma under a State-wide health department program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989995"}
{"pmid": "20989996", "title": "Looking ahead in health service.", "content": "Looking ahead in health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989996"}
{"pmid": "20989997", "title": "Future prospects for physicians.", "content": "Future prospects for physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989997"}
{"pmid": "20989998", "title": "Biliary obstruction in the newborn with recovery.", "content": "Biliary obstruction in the newborn with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989998"}
{"pmid": "20990000", "title": "Hypersensitization, a phase in chronic infectious diseases.", "content": "Hypersensitization, a phase in chronic infectious diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990000"}
{"pmid": "20989999", "title": "An evaluation of surgical treatment of internal derangements of the knee in an Army general hospital.", "content": "An evaluation of surgical treatment of internal derangements of the knee in an Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20989999"}
{"pmid": "20990003", "title": "The control of arterial hypertension.", "content": "The control of arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990003"}
{"pmid": "20990001", "title": "The several varieties of actinomycosis.", "content": "The several varieties of actinomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990001"}
{"pmid": "20990002", "title": "Surgery of the colon; traumatic and elective.", "content": "Surgery of the colon; traumatic and elective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990002"}
{"pmid": "20990004", "title": "The medical regime in vascular hypertension.", "content": "The medical regime in vascular hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990004"}
{"pmid": "20990005", "title": "The therapeutics of hyperpiesia.", "content": "The therapeutics of hyperpiesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990005"}
{"pmid": "20990006", "title": "Some physiological aspects of human vascular hypertension.", "content": "Some physiological aspects of human vascular hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990006"}
{"pmid": "20990007", "title": "The surgical treatment of essential hypertension.", "content": "The surgical treatment of essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990007"}
{"pmid": "20990016", "title": "The diagnosis of breast lesions.", "content": "The diagnosis of breast lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990016"}
{"pmid": "20990017", "title": "Allantoin-sulfanilamide ointment in the general practice of medicine.", "content": "Allantoin-sulfanilamide ointment in the general practice of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990017"}
{"pmid": "20990018", "title": "Post-war adjustments in medicine.", "content": "Post-war adjustments in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990018"}
{"pmid": "20990019", "title": "Despise not the day of small beginnings [Tuskegee Institute history].", "content": "Despise not the day of small beginnings [Tuskegee Institute history].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990019"}
{"pmid": "20990020", "title": "Statement in support of National Health Bill S. 1606, on behalf of the National Association for the Advancement of Colored People.", "content": "Statement in support of National Health Bill S. 1606, on behalf of the National Association for the Advancement of Colored People.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990020"}
{"pmid": "20990021", "title": "Rheumatic myocarditis.", "content": "Rheumatic myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990021"}
{"pmid": "20990022", "title": "Endocrine complaints in the eye, ear, nose and throat area.", "content": "Endocrine complaints in the eye, ear, nose and throat area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990022"}
{"pmid": "20990023", "title": "Surgery in the treatment of the stomach and duodenum.", "content": "Surgery in the treatment of the stomach and duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990023"}
{"pmid": "20990024", "title": "Lymphatic leukemia.", "content": "Lymphatic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990024"}
{"pmid": "20990025", "title": "Dysmenorrhea and spontaneous abortion; a physiologic defect in the myometrium not related to corpus luteum failure.", "content": "Dysmenorrhea and spontaneous abortion; a physiologic defect in the myometrium not related to corpus luteum failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990025"}
{"pmid": "20990026", "title": "Asthma caused by stasis of the ascending colon.", "content": "Asthma caused by stasis of the ascending colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990026"}
{"pmid": "20990027", "title": "Obstetrical analgesia.", "content": "Obstetrical analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990027"}
{"pmid": "20990028", "title": "Ethology, transmission and prophylaxis of dengue.", "content": "Ethology, transmission and prophylaxis of dengue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990028"}
{"pmid": "20990029", "title": "Foreign bodies in the hypopharynx and oesophagus.", "content": "Foreign bodies in the hypopharynx and oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990029"}
{"pmid": "20990030", "title": "Contribution of the Arabs to materia medica.", "content": "Contribution of the Arabs to materia medica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990030"}
{"pmid": "20990031", "title": "Virus pneumonia.", "content": "Virus pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990031"}
{"pmid": "20990032", "title": "Hernia repair; analysis of 72 cases.", "content": "Hernia repair; analysis of 72 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990032"}
{"pmid": "20990033", "title": "Rheumatic fever; a clinical survey of 542 cases, with reference to unusual precipitating factors, case reports.", "content": "Rheumatic fever; a clinical survey of 542 cases, with reference to unusual precipitating factors, case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990033"}
{"pmid": "20990034", "title": "Rheumatic fever following penicillin therapy.", "content": "Rheumatic fever following penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990034"}
{"pmid": "20990035", "title": "A summary of meningococcal infections admitted to the isolation ward of the Louisville General Hospital for the year 1944.", "content": "A summary of meningococcal infections admitted to the isolation ward of the Louisville General Hospital for the year 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990035"}
{"pmid": "20990036", "title": "Carcinoid tumor of the appendix.", "content": "Carcinoid tumor of the appendix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990036"}
{"pmid": "20990050", "title": "Phenylketonuria; a problem in eugenics.", "content": "Phenylketonuria; a problem in eugenics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990050"}
{"pmid": "20990051", "title": "Pain of organic disease relieved by prefrontal lobotomy.", "content": "Pain of organic disease relieved by prefrontal lobotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990051"}
{"pmid": "20990052", "title": "Laboratory diagnosis of Weil's disease.", "content": "Laboratory diagnosis of Weil's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990052"}
{"pmid": "20990053", "title": "Subacute hepatic necrosis treated with methionine.", "content": "Subacute hepatic necrosis treated with methionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990053"}
{"pmid": "20990054", "title": "Burning feet in British prisoners-of-war in the Far East.", "content": "Burning feet in British prisoners-of-war in the Far East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990054"}
{"pmid": "20990055", "title": "Nutritional deficiency, painful feet, high blood-pressure in Hong Kong.", "content": "Nutritional deficiency, painful feet, high blood-pressure in Hong Kong.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990055"}
{"pmid": "20990056", "title": "WORLD'S food; subsistence and maintenance levels.", "content": "WORLD'S food; subsistence and maintenance levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990056"}
{"pmid": "20990057", "title": "POLIOMYELITIS in boarding-schools.", "content": "POLIOMYELITIS in boarding-schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990057"}
{"pmid": "20990058", "title": "Homologous serum hepatitis.", "content": "Homologous serum hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990058"}
{"pmid": "20990059", "title": "QUALIFICATIONS of the specialist surgeon.", "content": "QUALIFICATIONS of the specialist surgeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990059"}
{"pmid": "20990060", "title": "The differential diagnosis of ocular pain.", "content": "The differential diagnosis of ocular pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990060"}
{"pmid": "20990061", "title": "Control of lead poisoning.", "content": "Control of lead poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990061"}
{"pmid": "20990062", "title": "A case of bilateral abductor paralysis treated by the Brien King operation.", "content": "A case of bilateral abductor paralysis treated by the Brien King operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990062"}
{"pmid": "20990063", "title": "Stabilizing the knee joint through thigh muscle development.", "content": "Stabilizing the knee joint through thigh muscle development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990063"}
{"pmid": "20990064", "title": "A theory for the fundamental change in malignancy.", "content": "A theory for the fundamental change in malignancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990064"}
{"pmid": "20990065", "title": "Clinical pathological conference; periarteritis nodosa.", "content": "Clinical pathological conference; periarteritis nodosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990065"}
{"pmid": "20990066", "title": "Histamine and allergy.", "content": "Histamine and allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990066"}
{"pmid": "20990074", "title": "What compulsory medical care would cost eventually.", "content": "What compulsory medical care would cost eventually.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990074"}
{"pmid": "20990075", "title": "The Nicollet Clinic.", "content": "The Nicollet Clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990075"}
{"pmid": "20990076", "title": "The consequences of S.1606.", "content": "The consequences of S.1606.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990076"}
{"pmid": "20990077", "title": "Gunfire deafness.", "content": "Gunfire deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990077"}
{"pmid": "20990078", "title": "The Borstal age; the case for experiment.", "content": "The Borstal age; the case for experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990078"}
{"pmid": "20990079", "title": "Some aspects of neglect and maltreatment in venereal disease.", "content": "Some aspects of neglect and maltreatment in venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990079"}
{"pmid": "20990080", "title": "Diethylstilbestrol in dysfunctional, incomplete and post partum uterine bleeding with or without myomas and menorrhagia in maltreatment in venereal disease.", "content": "Diethylstilbestrol in dysfunctional, incomplete and post partum uterine bleeding with or without myomas and menorrhagia in maltreatment in venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990080"}
{"pmid": "20990081", "title": "Diethylstilbestrol in dysfunctional, incomplete and post partum uterine bleeding with or without myomas and menorrhagia in non-cancerous conditions.", "content": "Diethylstilbestrol in dysfunctional, incomplete and post partum uterine bleeding with or without myomas and menorrhagia in non-cancerous conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990081"}
{"pmid": "20990082", "title": "The role of physical procedures in the treatment of anterior poliomyelitis.", "content": "The role of physical procedures in the treatment of anterior poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990082"}
{"pmid": "20990083", "title": "What is myocarditis?", "content": "What is myocarditis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990083"}
{"pmid": "20990084", "title": "A resume of the management of cancer of the rectum and colon.", "content": "A resume of the management of cancer of the rectum and colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990084"}
{"pmid": "20990085", "title": "Acute isolated myocarditis.", "content": "Acute isolated myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990085"}
{"pmid": "20990086", "title": "Fracture of the humerus about the surgical neck, with closed reduction and blind pinning.", "content": "Fracture of the humerus about the surgical neck, with closed reduction and blind pinning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990086"}
{"pmid": "20990087", "title": "WOMEN'S Medical College of Chicago.", "content": "WOMEN'S Medical College of Chicago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990087"}
{"pmid": "20990088", "title": "Chronic ill-health and absenteeism.", "content": "Chronic ill-health and absenteeism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990088"}
{"pmid": "20990089", "title": "The aetiology of some common ocular conditions met with in general practice.", "content": "The aetiology of some common ocular conditions met with in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990089"}
{"pmid": "20990090", "title": "Late middle age.", "content": "Late middle age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990090"}
{"pmid": "20990091", "title": "Cancer of the stomach.", "content": "Cancer of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990091"}
{"pmid": "20990092", "title": "Abnormal movements in childhood.", "content": "Abnormal movements in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990092"}
{"pmid": "20990093", "title": "Late middle age.", "content": "Late middle age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990093"}
{"pmid": "20990098", "title": "Gastric surgery.", "content": "Gastric surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990098"}
{"pmid": "20990100", "title": "Hematology.", "content": "Hematology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990100"}
{"pmid": "20990099", "title": "Acute hemolytic anemia in primary atypical pneumonia associated with high titer of cold agglutinins; report of a case.", "content": "Acute hemolytic anemia in primary atypical pneumonia associated with high titer of cold agglutinins; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990099"}
{"pmid": "20990101", "title": "Pulmonary metastasis from adenoacanthoma of uterus; clinocopathological exercises.", "content": "Pulmonary metastasis from adenoacanthoma of uterus; clinocopathological exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990101"}
{"pmid": "20990102", "title": "Adenoma of bronchus; clinicopathological exercises.", "content": "Adenoma of bronchus; clinicopathological exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990102"}
{"pmid": "20990103", "title": "Disputed indications and technics for cesarean section.", "content": "Disputed indications and technics for cesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990103"}
{"pmid": "20990104", "title": "The treatment of bacterial arthritis with penicillin.", "content": "The treatment of bacterial arthritis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990104"}
{"pmid": "20990105", "title": "Three years' experience with electric convulsive therapy.", "content": "Three years' experience with electric convulsive therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990105"}
{"pmid": "20990106", "title": "Gynecology: carcinoma of the vulva.", "content": "Gynecology: carcinoma of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990106"}
{"pmid": "20990107", "title": "Hemochromatosis; clinicopathological exercises.", "content": "Hemochromatosis; clinicopathological exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990107"}
{"pmid": "20990108", "title": "Actinomycotic abscesses of peritoneum and liver, with perforation of right diaphragm; clinicopathological exercises.", "content": "Actinomycotic abscesses of peritoneum and liver, with perforation of right diaphragm; clinicopathological exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990108"}
{"pmid": "20990109", "title": "Ligation of the inferior vena cava or iliac veins.", "content": "Ligation of the inferior vena cava or iliac veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990109"}
{"pmid": "20990110", "title": "Neuropsychiatry in the European theater of operations.", "content": "Neuropsychiatry in the European theater of operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990110"}
{"pmid": "20990111", "title": "Infectious diabetic gangrene of the skin of the neck.", "content": "Infectious diabetic gangrene of the skin of the neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990111"}
{"pmid": "20990112", "title": "Endoscopy.", "content": "Endoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990112"}
{"pmid": "20990113", "title": "Pinealoma.", "content": "Pinealoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990113"}
{"pmid": "20990114", "title": "Tuberculosis of kidney.", "content": "Tuberculosis of kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990114"}
{"pmid": "20990115", "title": "Gangrene of the hand following treatment for pruritus of hepatotoxic origin.", "content": "Gangrene of the hand following treatment for pruritus of hepatotoxic origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990115"}
{"pmid": "20990117", "title": "Primitive medicine.", "content": "Primitive medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990117"}
{"pmid": "20990116", "title": "The Dick test in military personnel, with special reference to the pathogenesis of the skin reaction.", "content": "The Dick test in military personnel, with special reference to the pathogenesis of the skin reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990116"}
{"pmid": "20990118", "title": "Ureteral catheterization.", "content": "Ureteral catheterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990118"}
{"pmid": "20990119", "title": "Malignant lymphoma involving retroperitoneal tissues and meninges of spinal cord.", "content": "Malignant lymphoma involving retroperitoneal tissues and meninges of spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990119"}
{"pmid": "20990120", "title": "Acute and chronic cholecystitis.", "content": "Acute and chronic cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990120"}
{"pmid": "20990121", "title": "Sarcoidosis.", "content": "Sarcoidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990121"}
{"pmid": "20990122", "title": "The psychiatric patient, problems of management.", "content": "The psychiatric patient, problems of management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990122"}
{"pmid": "20990123", "title": "The internal carotid artery; an anatomical and clinical correlation.", "content": "The internal carotid artery; an anatomical and clinical correlation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990123"}
{"pmid": "20990124", "title": "Spontaneous pneumothorax.", "content": "Spontaneous pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990124"}
{"pmid": "20990125", "title": "The surgeon looks at general practice.", "content": "The surgeon looks at general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990125"}
{"pmid": "20990126", "title": "Men, money and medicine.", "content": "Men, money and medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990126"}
{"pmid": "20990127", "title": "Intussusception in children, report of a successful primary resection.", "content": "Intussusception in children, report of a successful primary resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990127"}
{"pmid": "20990129", "title": "Treatment in psychiatry.", "content": "Treatment in psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990129"}
{"pmid": "20990128", "title": "Some recollections of a year with field medical units in the Middle East.", "content": "Some recollections of a year with field medical units in the Middle East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990128"}
{"pmid": "20990130", "title": "Forward war surgery.", "content": "Forward war surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990130"}
{"pmid": "20990131", "title": "Observations on the management of chest injuries from the medical aspect.", "content": "Observations on the management of chest injuries from the medical aspect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990131"}
{"pmid": "20990132", "title": "Experiences in a 600 bed hospital in Normandy.", "content": "Experiences in a 600 bed hospital in Normandy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990132"}
{"pmid": "20990133", "title": "Post-partum tuberculous salpingitis with terminal miliary tuberculosis and hemiparesis.", "content": "Post-partum tuberculous salpingitis with terminal miliary tuberculosis and hemiparesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990133"}
{"pmid": "20990134", "title": "Treatment of congenital hemangioma.", "content": "Treatment of congenital hemangioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990134"}
{"pmid": "20990135", "title": "Recent advances in the treatment of compound fractures.", "content": "Recent advances in the treatment of compound fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990135"}
{"pmid": "20990136", "title": "Low back pain.", "content": "Low back pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990136"}
{"pmid": "20990137", "title": "Symposium on obstetric care.", "content": "Symposium on obstetric care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990137"}
{"pmid": "20990138", "title": "Arthritis and rainfall.", "content": "Arthritis and rainfall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990138"}
{"pmid": "20990139", "title": "An analysis of unsanitary spots found on plantations.", "content": "An analysis of unsanitary spots found on plantations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990139"}
{"pmid": "20990140", "title": "Suppurative cholangitis complicating sidetracking operations of the biliary tract.", "content": "Suppurative cholangitis complicating sidetracking operations of the biliary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990140"}
{"pmid": "20990141", "title": "Pancreatic heterotopia.", "content": "Pancreatic heterotopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990141"}
{"pmid": "20990183", "title": "Some observations on diseases seen in India and their importance in civilian practice.", "content": "Some observations on diseases seen in India and their importance in civilian practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990183"}
{"pmid": "20990184", "title": "Streptococcal septicaemia; report of a case treated with penicillin.", "content": "Streptococcal septicaemia; report of a case treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990184"}
{"pmid": "20990185", "title": "Penicillin-sensitive staphylococci; report of laboratory procedures.", "content": "Penicillin-sensitive staphylococci; report of laboratory procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990185"}
{"pmid": "20990201", "title": "Problems of nomenclature of certain pathogenic rickettsiae and rickettsial diseases.", "content": "Problems of nomenclature of certain pathogenic rickettsiae and rickettsial diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990201"}
{"pmid": "20990202", "title": "Functional mitral diastolic murmurs.", "content": "Functional mitral diastolic murmurs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990202"}
{"pmid": "20990203", "title": "Histamine, its physiological, pharmacological and clinical significance.", "content": "Histamine, its physiological, pharmacological and clinical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990203"}
{"pmid": "20990204", "title": "Health problems of the Amazon Valley.", "content": "Health problems of the Amazon Valley.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990204"}
{"pmid": "20990205", "title": "Anti-rickettsial activity of para-aminobenzoic acid (PABA); effect of PABA on experimental spotted fever.", "content": "Anti-rickettsial activity of para-aminobenzoic acid (PABA); effect of PABA on experimental spotted fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990205"}
{"pmid": "20990206", "title": "Evidence on the influence of altitude on allergic symptoms in children.", "content": "Evidence on the influence of altitude on allergic symptoms in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990206"}
{"pmid": "20990219", "title": "The use of thrombin in the control of post-prostatic resection blood loss.", "content": "The use of thrombin in the control of post-prostatic resection blood loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990219"}
{"pmid": "20990222", "title": "Hemiplegia.", "content": "Hemiplegia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990222"}
{"pmid": "20990223", "title": "Thiouracil.", "content": "Thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990223"}
{"pmid": "20990224", "title": "Roentgen therapy of pituitary adenomas.", "content": "Roentgen therapy of pituitary adenomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990224"}
{"pmid": "20990225", "title": "Liabilities in the indiscriminate use of curare.", "content": "Liabilities in the indiscriminate use of curare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990225"}
{"pmid": "20990226", "title": "The bromsulphalein test of liver function.", "content": "The bromsulphalein test of liver function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990226"}
{"pmid": "20990227", "title": "NURSES and tuberculosis.", "content": "NURSES and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990227"}
{"pmid": "20990229", "title": "Sarcoidosis.", "content": "Sarcoidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990229"}
{"pmid": "20990228", "title": "Classification of cirrhosis of the liver.", "content": "Classification of cirrhosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990228"}
{"pmid": "20990230", "title": "Non-putrid pulmonary abscess.", "content": "Non-putrid pulmonary abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990230"}
{"pmid": "20990231", "title": "Acute interstitial pneumonitis.", "content": "Acute interstitial pneumonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990231"}
{"pmid": "20990232", "title": "Poliomyelitis.", "content": "Poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990232"}
{"pmid": "20990233", "title": "Cerebral schistosomiasis.", "content": "Cerebral schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990233"}
{"pmid": "20990250", "title": "Concerning the cancer problem.", "content": "Concerning the cancer problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990250"}
{"pmid": "20990251", "title": "The shape of cells as a mathematical problem.", "content": "The shape of cells as a mathematical problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990251"}
{"pmid": "20990252", "title": "On the active and passive exchanges of ions through cell surfaces and membranes in general.", "content": "On the active and passive exchanges of ions through cell surfaces and membranes in general.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990252"}
{"pmid": "20990253", "title": "The introduction of curare into clinical medicine; present and potential usefulness.", "content": "The introduction of curare into clinical medicine; present and potential usefulness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990253"}
{"pmid": "20990254", "title": "The future of scientific research in the post war world.", "content": "The future of scientific research in the post war world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990254"}
{"pmid": "20990255", "title": "Science and art; an approach to a new synthesis.", "content": "Science and art; an approach to a new synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990255"}
{"pmid": "20990256", "title": "Scientific Russian.", "content": "Scientific Russian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990256"}
{"pmid": "20990257", "title": "Position effect and the theory of the corpuscular gene.", "content": "Position effect and the theory of the corpuscular gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990257"}
{"pmid": "20990258", "title": "Water relations of insects.", "content": "Water relations of insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990258"}
{"pmid": "20990263", "title": "Estimation and physiological role of solanine in the potato.", "content": "Estimation and physiological role of solanine in the potato.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990263"}
{"pmid": "20990264", "title": "The Cherokee green corn medicine and the green corn festival.", "content": "The Cherokee green corn medicine and the green corn festival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990264"}
{"pmid": "20990265", "title": "The Philippine mosquitoes of the genus Aedes, subgenus Aedes.", "content": "The Philippine mosquitoes of the genus Aedes, subgenus Aedes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990265"}
{"pmid": "20990266", "title": "Some recent developments in the field of electron microscopy.", "content": "Some recent developments in the field of electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990266"}
{"pmid": "20990267", "title": "Radiochemical changes in some fatty acids.", "content": "Radiochemical changes in some fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990267"}
{"pmid": "20990268", "title": "Surface phagocytosis; its relation to the mechanism of recovery in pneumococcal pneumonia.", "content": "Surface phagocytosis; its relation to the mechanism of recovery in pneumococcal pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990268"}
{"pmid": "20990269", "title": "Transplantation of adult filarial worms, Litomosoides carinii, in cotton rats.", "content": "Transplantation of adult filarial worms, Litomosoides carinii, in cotton rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990269"}
{"pmid": "20990270", "title": "The effect of thiouracil upon pigmentation in the tadpole.", "content": "The effect of thiouracil upon pigmentation in the tadpole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990270"}
{"pmid": "20990271", "title": "Modifications of specimens in electron microscopy.", "content": "Modifications of specimens in electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990271"}
{"pmid": "20990272", "title": "Frozen-dried preparations for the electron microscope.", "content": "Frozen-dried preparations for the electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990272"}
{"pmid": "20990274", "title": "Some thoughts on gene action.", "content": "Some thoughts on gene action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990274"}
{"pmid": "20990273", "title": "On the mechanism of action of folic acid and liver extract in the treatment of anemia.", "content": "On the mechanism of action of folic acid and liver extract in the treatment of anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990273"}
{"pmid": "20990286", "title": "Occurrence of multiple neuritis in cases of cutaneous diphtheria.", "content": "Occurrence of multiple neuritis in cases of cutaneous diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990286"}
{"pmid": "20990287", "title": "Prognosis in so-called sciatic neuritis.", "content": "Prognosis in so-called sciatic neuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990287"}
{"pmid": "20990288", "title": "Similarity of cerebral arteriovenous oxygen differences on right and left sides in resting man.", "content": "Similarity of cerebral arteriovenous oxygen differences on right and left sides in resting man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990288"}
{"pmid": "20990289", "title": "Phenomena of sensory suppression.", "content": "Phenomena of sensory suppression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990289"}
{"pmid": "20990290", "title": "Bilateral congenital arteriovenous communications (aneurysm) of the cerebral vessels.", "content": "Bilateral congenital arteriovenous communications (aneurysm) of the cerebral vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990290"}
{"pmid": "20990291", "title": "Arteriographic visualization of cerebrovascular lesions.", "content": "Arteriographic visualization of cerebrovascular lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990291"}
{"pmid": "20990292", "title": "Electroencephalographic studies of psychopathic personalities.", "content": "Electroencephalographic studies of psychopathic personalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990292"}
{"pmid": "20990293", "title": "Phenomena of fluctuation, extinction and completion in visual perception.", "content": "Phenomena of fluctuation, extinction and completion in visual perception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990293"}
{"pmid": "20990294", "title": "Progressive hemiplegia.", "content": "Progressive hemiplegia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990294"}
{"pmid": "20990295", "title": "Surgical repair of defects of the skull.", "content": "Surgical repair of defects of the skull.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990295"}
{"pmid": "20990296", "title": "Psychophysiologic interrelationships.", "content": "Psychophysiologic interrelationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990296"}
{"pmid": "20990297", "title": "Ménière's syndrome; comparison of the results of medical and surgical treatment.", "content": "Ménière's syndrome; comparison of the results of medical and surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990297"}
{"pmid": "20990298", "title": "Clinical diagnosis of disturbances of the central sympathetic system by means of pupillography.", "content": "Clinical diagnosis of disturbances of the central sympathetic system by means of pupillography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990298"}
{"pmid": "20990306", "title": "The twentieth Maudsley lecture: psychiatry and the public health service.", "content": "The twentieth Maudsley lecture: psychiatry and the public health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990306"}
{"pmid": "20990307", "title": "Vitamin B complex in relation to neuropsychiatry.", "content": "Vitamin B complex in relation to neuropsychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990307"}
{"pmid": "20990308", "title": "Vitamin B deficiency and the psychoses; clinical aspects.", "content": "Vitamin B deficiency and the psychoses; clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990308"}
{"pmid": "20990310", "title": "Persistent enuresis; a psychosomatic study.", "content": "Persistent enuresis; a psychosomatic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990310"}
{"pmid": "20990311", "title": "The mental health of submariners, with special reference to 71 cases examined psychiatrically.", "content": "The mental health of submariners, with special reference to 71 cases examined psychiatrically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990311"}
{"pmid": "20990312", "title": "On the aetiology of stuttering.", "content": "On the aetiology of stuttering.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990312"}
{"pmid": "20990309", "title": "Principles for the quantitative study of stability in a dynamic whole system; with some applications to the nervous system.", "content": "Principles for the quantitative study of stability in a dynamic whole system; with some applications to the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990309"}
{"pmid": "20990313", "title": "Jakob-Creutzfeldt disease.", "content": "Jakob-Creutzfeldt disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990313"}
{"pmid": "20990314", "title": "Unawareness of physical disability (anosognosia).", "content": "Unawareness of physical disability (anosognosia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990314"}
{"pmid": "20990315", "title": "Personality defects and psychiatric symptoms after cerebrospinal fever in childhood: meningococcal encephalopathy.", "content": "Personality defects and psychiatric symptoms after cerebrospinal fever in childhood: meningococcal encephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990315"}
{"pmid": "20990316", "title": "The use of curare with convulsive therapy.", "content": "The use of curare with convulsive therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990316"}
{"pmid": "20990317", "title": "The early results of penicillin treatment in G. P. I.", "content": "The early results of penicillin treatment in G. P. I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990317"}
{"pmid": "20990319", "title": "PSYCHIATRIC disorders and reactions: definitions and manner of recording.", "content": "PSYCHIATRIC disorders and reactions: definitions and manner of recording.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990319"}
{"pmid": "20990320", "title": "Nutritional deficiency and sound-induced convulsive seizures in the rat.", "content": "Nutritional deficiency and sound-induced convulsive seizures in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990320"}
{"pmid": "20990318", "title": "The treatment of cerebral palsy.", "content": "The treatment of cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990318"}
{"pmid": "20990325", "title": "Cancer in childhood.", "content": "Cancer in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990325"}
{"pmid": "20990326", "title": "Emotional factors in surgical nursing.", "content": "Emotional factors in surgical nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990326"}
{"pmid": "20990327", "title": "The nurse in the day-care center.", "content": "The nurse in the day-care center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990327"}
{"pmid": "20990328", "title": "Nursing in South Africa.", "content": "Nursing in South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990328"}
{"pmid": "20990329", "title": "COMMUNITY planning for nursing service.", "content": "COMMUNITY planning for nursing service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990329"}
{"pmid": "20990330", "title": "The cerebral palsy child; diagnosis and treatment.", "content": "The cerebral palsy child; diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990330"}
{"pmid": "20990331", "title": "Nursing responsibilities in cerebral palsy.", "content": "Nursing responsibilities in cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990331"}
{"pmid": "20990332", "title": "Approach to a cost study.", "content": "Approach to a cost study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990332"}
{"pmid": "20990333", "title": "Anemia in pregnancy and the postpartum.", "content": "Anemia in pregnancy and the postpartum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990333"}
{"pmid": "20990334", "title": "The camp nurse.", "content": "The camp nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990334"}
{"pmid": "20990335", "title": "Training auxiliary workers.", "content": "Training auxiliary workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990335"}
{"pmid": "20990336", "title": "Field problems in orthopedic treatment.", "content": "Field problems in orthopedic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990336"}
{"pmid": "20990338", "title": "Preschool habit training.", "content": "Preschool habit training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990338"}
{"pmid": "20990343", "title": "Early rising for the post-operative patient.", "content": "Early rising for the post-operative patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990343"}
{"pmid": "20990342", "title": "The nursing care of blue babies.", "content": "The nursing care of blue babies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990342"}
{"pmid": "20990344", "title": "Nurse's responsibility in blood transfusion.", "content": "Nurse's responsibility in blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990344"}
{"pmid": "20990345", "title": "Abdominal enlargement and ovarian cysts.", "content": "Abdominal enlargement and ovarian cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990345"}
{"pmid": "20990346", "title": "Early failure of breast feeding; milk tension and engorgement.", "content": "Early failure of breast feeding; milk tension and engorgement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990346"}
{"pmid": "20990347", "title": "Perforated duodenal ulcer in a child of 12 years.", "content": "Perforated duodenal ulcer in a child of 12 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990347"}
{"pmid": "20990348", "title": "Use of urea-formaldehyde in orthopaedic surgery.", "content": "Use of urea-formaldehyde in orthopaedic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990348"}
{"pmid": "20990349", "title": "Technique of partial gastrectomy.", "content": "Technique of partial gastrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990349"}
{"pmid": "20990350", "title": "Social pathology of rheumatic fever.", "content": "Social pathology of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990350"}
{"pmid": "20990351", "title": "Making nursing history in a Vienna hospital.", "content": "Making nursing history in a Vienna hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990351"}
{"pmid": "20990353", "title": "Abnormal uterine action.", "content": "Abnormal uterine action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990353"}
{"pmid": "20990352", "title": "Cancer of the rectum, with emphasis on abdomino-perineal resection.", "content": "Cancer of the rectum, with emphasis on abdomino-perineal resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990352"}
{"pmid": "20990354", "title": "Health centres.", "content": "Health centres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990354"}
{"pmid": "20990355", "title": "Mothercraft teaching in rural areas.", "content": "Mothercraft teaching in rural areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990355"}
{"pmid": "20990356", "title": "CARE of the child deprived of normal home life.", "content": "CARE of the child deprived of normal home life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990356"}
{"pmid": "20990357", "title": "Penicillin in the treatment of bacterial endocarditis.", "content": "Penicillin in the treatment of bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990357"}
{"pmid": "20990358", "title": "Nursing in other lands; Italy.", "content": "Nursing in other lands; Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990358"}
{"pmid": "20990359", "title": "The effects of malnutrition.", "content": "The effects of malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990359"}
{"pmid": "20990360", "title": "Social medicine.", "content": "Social medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990360"}
{"pmid": "20990361", "title": "Modernizing practices in maternity hospitals and newborn baby services.", "content": "Modernizing practices in maternity hospitals and newborn baby services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990361"}
{"pmid": "20990362", "title": "UNRRA nurses in Europe 1946.", "content": "UNRRA nurses in Europe 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990362"}
{"pmid": "20990363", "title": "We put on an exhibit.", "content": "We put on an exhibit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990363"}
{"pmid": "20990364", "title": "Diet in relation to poliomyelitis.", "content": "Diet in relation to poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990364"}
{"pmid": "20990365", "title": "GUIDE to organizing a community group interested in nursing services; some principles.", "content": "GUIDE to organizing a community group interested in nursing services; some principles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990365"}
{"pmid": "20990367", "title": "Maternity and child welfare.", "content": "Maternity and child welfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990367"}
{"pmid": "20990366", "title": "Thumbsucking.", "content": "Thumbsucking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990366"}
{"pmid": "20990368", "title": "Careers; physiotherapy.", "content": "Careers; physiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990368"}
{"pmid": "20990370", "title": "Anesthesia.", "content": "Anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990370"}
{"pmid": "20990371", "title": "Registration.", "content": "Registration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990371"}
{"pmid": "20990372", "title": "Alcoholism; its recognition and defeat.", "content": "Alcoholism; its recognition and defeat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990372"}
{"pmid": "20990374", "title": "What is being done for the partially seeing child?", "content": "What is being done for the partially seeing child?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990374"}
{"pmid": "20990373", "title": "Predecessors of penicillin.", "content": "Predecessors of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990373"}
{"pmid": "20990375", "title": "The correlation of optometric binocular measurements for refractive diagnosis.", "content": "The correlation of optometric binocular measurements for refractive diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990375"}
{"pmid": "20990377", "title": "Color vision and recent developments in color vision testing.", "content": "Color vision and recent developments in color vision testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990377"}
{"pmid": "20990376", "title": "Optical principles for contact lenses.", "content": "Optical principles for contact lenses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990376"}
{"pmid": "20990378", "title": "Transplantation of human vitreous.", "content": "Transplantation of human vitreous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990378"}
{"pmid": "20990379", "title": "Suprasellar meningiomas associated with scotomatous field defects.", "content": "Suprasellar meningiomas associated with scotomatous field defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990379"}
{"pmid": "20990380", "title": "Hydrogen ion concentration of the aqueous.", "content": "Hydrogen ion concentration of the aqueous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990380"}
{"pmid": "20990369", "title": "SOME new aspects of breast-feeding.", "content": "SOME new aspects of breast-feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990369"}
{"pmid": "20990381", "title": "Treatment of chronic blepharoconjunctivitis with penicillin ointment.", "content": "Treatment of chronic blepharoconjunctivitis with penicillin ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990381"}
{"pmid": "20990382", "title": "Heredodegenerative diseases of the retina.", "content": "Heredodegenerative diseases of the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990382"}
{"pmid": "20990383", "title": "Action spectrum of keratitis produced by ultraviolet radiation.", "content": "Action spectrum of keratitis produced by ultraviolet radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990383"}
{"pmid": "20990384", "title": "Intraorbital melanosis and intracranial neuroepithelioma of the optic nerve.", "content": "Intraorbital melanosis and intracranial neuroepithelioma of the optic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990384"}
{"pmid": "20990385", "title": "Use of penicillin ointment in external ocular conditions.", "content": "Use of penicillin ointment in external ocular conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990385"}
{"pmid": "20990386", "title": "Neurofibromatosis occurring in three consecutive generations.", "content": "Neurofibromatosis occurring in three consecutive generations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990386"}
{"pmid": "20990387", "title": "Early ocular pemphigus.", "content": "Early ocular pemphigus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990387"}
{"pmid": "20990388", "title": "Herpes zoster ophthalmicus appearing after trauma.", "content": "Herpes zoster ophthalmicus appearing after trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990388"}
{"pmid": "20990389", "title": "Surgical methods of treating paralysis of the superior oblique muscle.", "content": "Surgical methods of treating paralysis of the superior oblique muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990389"}
{"pmid": "20990392", "title": "A statistical analysis of persons certified blind in Scotland.", "content": "A statistical analysis of persons certified blind in Scotland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990392"}
{"pmid": "20990393", "title": "Local treatment of intrabulbar infections; treatment of staphylococcus panophthalmia by intrabulbar injection of penicillin.", "content": "Local treatment of intrabulbar infections; treatment of staphylococcus panophthalmia by intrabulbar injection of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990393"}
{"pmid": "20990394", "title": "Retinal detachment due to war trauma.", "content": "Retinal detachment due to war trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990394"}
{"pmid": "20990395", "title": "Localization of intra-ocular foreign bodies.", "content": "Localization of intra-ocular foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990395"}
{"pmid": "20990399", "title": "Application of telescopic and microscopic spectacles in subnormal vision; psychological factors.", "content": "Application of telescopic and microscopic spectacles in subnormal vision; psychological factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990399"}
{"pmid": "20990400", "title": "How inefficient vision causes industrial accidents.", "content": "How inefficient vision causes industrial accidents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990400"}
{"pmid": "20990401", "title": "Responsibility of the social agency for protection of eyesight.", "content": "Responsibility of the social agency for protection of eyesight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990401"}
{"pmid": "20990402", "title": "Basic eye information in the training of workers.", "content": "Basic eye information in the training of workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990402"}
{"pmid": "20990403", "title": "Effective methods in the development of a prevention of blindness program.", "content": "Effective methods in the development of a prevention of blindness program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990403"}
{"pmid": "20990404", "title": "The case work aspects of medical eye care.", "content": "The case work aspects of medical eye care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990404"}
{"pmid": "20990405", "title": "Rehabilitation of the partially seeing.", "content": "Rehabilitation of the partially seeing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990405"}
{"pmid": "20990406", "title": "Causes of uniocular and binocular blindness in the U.S. Navy and U.S. Marine Corps in World War II.", "content": "Causes of uniocular and binocular blindness in the U.S. Navy and U.S. Marine Corps in World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990406"}
{"pmid": "20990407", "title": "Routine eye examination of school children.", "content": "Routine eye examination of school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990407"}
{"pmid": "20990408", "title": "Desensitization by histamine (histamine azoprotein) in vertigo, periodic headaches and vasomotor (allergic) rhinitis; review of the literature and report of 102 personal cases.", "content": "Desensitization by histamine (histamine azoprotein) in vertigo, periodic headaches and vasomotor (allergic) rhinitis; review of the literature and report of 102 personal cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990408"}
{"pmid": "20990409", "title": "The nasopharynx; a study of 140 autopsy specimens.", "content": "The nasopharynx; a study of 140 autopsy specimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990409"}
{"pmid": "20990410", "title": "What the otologist should know about the educational problems of deafness.", "content": "What the otologist should know about the educational problems of deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990410"}
{"pmid": "20990411", "title": "The management of the acute ear.", "content": "The management of the acute ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990411"}
{"pmid": "20990412", "title": "Report of a death from pontocaine hydrochloride.", "content": "Report of a death from pontocaine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990412"}
{"pmid": "20990413", "title": "Deaf children with multiple handicaps.", "content": "Deaf children with multiple handicaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990413"}
{"pmid": "20990419", "title": "Desensitization in allergic diseases in children.", "content": "Desensitization in allergic diseases in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990419"}
{"pmid": "20990420", "title": "The copper content in the cerebrospinal fluid.", "content": "The copper content in the cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990420"}
{"pmid": "20990423", "title": "Pain in the leg [endocarditis subacute bacterial].", "content": "Pain in the leg [endocarditis subacute bacterial].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990423"}
{"pmid": "20990424", "title": "Streptomycin in influenzal meningitis.", "content": "Streptomycin in influenzal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990424"}
{"pmid": "20990425", "title": "Swelling of the abdomen [liver carcinoma].", "content": "Swelling of the abdomen [liver carcinoma].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990425"}
{"pmid": "20990426", "title": "Paroxysmal auricular tachycardia.", "content": "Paroxysmal auricular tachycardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990426"}
{"pmid": "20990427", "title": "Congenital biliary atresia.", "content": "Congenital biliary atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990427"}
{"pmid": "20990428", "title": "Osteosarcoma of the left femur, with pulmonary metastasis.", "content": "Osteosarcoma of the left femur, with pulmonary metastasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990428"}
{"pmid": "20990432", "title": "[The diagnosis of congenital syphilis].", "content": "[The diagnosis of congenital syphilis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990432"}
{"pmid": "20990433", "title": "[The treatment of syphilis in children by means of novarsenol (myarsenol) and biochinol or mercury during one and the same day].", "content": "[The treatment of syphilis in children by means of novarsenol (myarsenol) and biochinol or mercury during one and the same day].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990433"}
{"pmid": "20990434", "title": "[The treatment of chemoresistant gonorrhea in children with antireticular cytotoxic serum].", "content": "[The treatment of chemoresistant gonorrhea in children with antireticular cytotoxic serum].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990434"}
{"pmid": "20990435", "title": "[Microorganisms, satellites of the gonococci in gonorrhea in children].", "content": "[Microorganisms, satellites of the gonococci in gonorrhea in children].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990435"}
{"pmid": "20990436", "title": "[On the sudden death of children in malaria].", "content": "[On the sudden death of children in malaria].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990436"}
{"pmid": "20990437", "title": "[Some peculiarities of the epidemiology and clinics of tertiana fulminans in children].", "content": "[Some peculiarities of the epidemiology and clinics of tertiana fulminans in children].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990437"}
{"pmid": "20990438", "title": "[On malarial encephalitis in children].", "content": "[On malarial encephalitis in children].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990438"}
{"pmid": "20990439", "title": "[Concerning inoculated malaria in sucklings].", "content": "[Concerning inoculated malaria in sucklings].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990439"}
{"pmid": "20990440", "title": "[On malaria in children].", "content": "[On malaria in children].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990440"}
{"pmid": "20990441", "title": "[Rheumatism in children in wartime].", "content": "[Rheumatism in children in wartime].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990441"}
{"pmid": "20990442", "title": "[Clinical characteristics of rheumatism in children during the war].", "content": "[Clinical characteristics of rheumatism in children during the war].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990442"}
{"pmid": "20990443", "title": "[The clinics of the latent form of rheumatism in children].", "content": "[The clinics of the latent form of rheumatism in children].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990443"}
{"pmid": "20990445", "title": "[Determination of the capacity of work of the cardiovascular system in child rheumatics by means of functional testing].", "content": "[Determination of the capacity of work of the cardiovascular system in child rheumatics by means of functional testing].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990445"}
{"pmid": "20990444", "title": "[The clinics of the catastrophic form of rheumatism in childhood].", "content": "[The clinics of the catastrophic form of rheumatism in childhood].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990444"}
{"pmid": "20990446", "title": "[Nephritis in children in wartime].", "content": "[Nephritis in children in wartime].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990446"}
{"pmid": "20990448", "title": "[The treatment of malaria in children with omnoquinon].", "content": "[The treatment of malaria in children with omnoquinon].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990448"}
{"pmid": "20990447", "title": "[The use of ovoprotein in the treatment of allergic illnesses in children].", "content": "[The use of ovoprotein in the treatment of allergic illnesses in children].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990447"}
{"pmid": "20990449", "title": "[Concerning salicylic therapy of rheumatism in children].", "content": "[Concerning salicylic therapy of rheumatism in children].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990449"}
{"pmid": "20990450", "title": "[Analysis of the discord between diagnoses of polyclinics and consultations, and clinical diagnoses.].", "content": "[Analysis of the discord between diagnoses of polyclinics and consultations, and clinical diagnoses.].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990450"}
{"pmid": "20990467", "title": "On the influence of hormones upon the metabolism of decapitated and eviscerated animals.", "content": "On the influence of hormones upon the metabolism of decapitated and eviscerated animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990467"}
{"pmid": "20990473", "title": "Social security pharmaceutical benefits in New Zealand.", "content": "Social security pharmaceutical benefits in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990473"}
{"pmid": "20990474", "title": "Cinnamon and cinnamon oil.", "content": "Cinnamon and cinnamon oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990474"}
{"pmid": "20990477", "title": "BRITISH penicillin mass produced.", "content": "BRITISH penicillin mass produced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990477"}
{"pmid": "20990478", "title": "Hexamethylene diamine.", "content": "Hexamethylene diamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990478"}
{"pmid": "20990479", "title": "ANALYSIS of the sulphonamides.", "content": "ANALYSIS of the sulphonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990479"}
{"pmid": "20990480", "title": "Studies of modern synthetic emulgents; the use of mixed emulgents.", "content": "Studies of modern synthetic emulgents; the use of mixed emulgents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990480"}
{"pmid": "20990481", "title": "Antacid preparations.", "content": "Antacid preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990481"}
{"pmid": "20990482", "title": "ANTIBIOTICS, including penicillin.", "content": "ANTIBIOTICS, including penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990482"}
{"pmid": "20990475", "title": "Pharmacy at New Haven Hospital.", "content": "Pharmacy at New Haven Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990475"}
{"pmid": "20990483", "title": "BENADRYL, a new control for allergies.", "content": "BENADRYL, a new control for allergies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990483"}
{"pmid": "20990485", "title": "The limits of pharmaceutical research.", "content": "The limits of pharmaceutical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990485"}
{"pmid": "20990484", "title": "Aloes; its microscopy and its anthracene constituents.", "content": "Aloes; its microscopy and its anthracene constituents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990484"}
{"pmid": "20990486", "title": "The coming of ether.", "content": "The coming of ether.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990486"}
{"pmid": "20990487", "title": "DEEP culture production of penicillin.", "content": "DEEP culture production of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990487"}
{"pmid": "20990488", "title": "Alkali treatment of the common cold.", "content": "Alkali treatment of the common cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990488"}
{"pmid": "20990489", "title": "HOW shall I qualify as a pharmacist? What do you advise?", "content": "HOW shall I qualify as a pharmacist? What do you advise?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990489"}
{"pmid": "20990476", "title": "STREPTOMYCIN.", "content": "STREPTOMYCIN.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990476"}
{"pmid": "20990490", "title": "DIPHTHERIA immunisation; a survey of the last five years.", "content": "DIPHTHERIA immunisation; a survey of the last five years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990490"}
{"pmid": "20990491", "title": "TINEA pedis (athletes foot); spread of infection among groups.", "content": "TINEA pedis (athletes foot); spread of infection among groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990491"}
{"pmid": "20990492", "title": "Dangerous birthmarks.", "content": "Dangerous birthmarks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990492"}
{"pmid": "20990504", "title": "INTOCOSTRIN in poliomyelitis.", "content": "INTOCOSTRIN in poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990504"}
{"pmid": "20990503", "title": "UP from the soil [antibiotics].", "content": "UP from the soil [antibiotics].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990503"}
{"pmid": "20990505", "title": "CONTROVERSIAL aspects of oral and topical penicillin therapy.", "content": "CONTROVERSIAL aspects of oral and topical penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990505"}
{"pmid": "20990506", "title": "The source and activity of Crago-darkening hormone.", "content": "The source and activity of Crago-darkening hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990506"}
{"pmid": "20990507", "title": "The nature of the growth-substance produced by Chilomonas paramecium.", "content": "The nature of the growth-substance produced by Chilomonas paramecium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990507"}
{"pmid": "20990508", "title": "Physiology of the ciliate Colpidium colpoda; the possible use of the division rate of Colpidium colpoda for identification of intestinal bacteria.", "content": "Physiology of the ciliate Colpidium colpoda; the possible use of the division rate of Colpidium colpoda for identification of intestinal bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990508"}
{"pmid": "20990509", "title": "Homotypic and heterotypic conditioning in relation to survival and growth of certain fishes.", "content": "Homotypic and heterotypic conditioning in relation to survival and growth of certain fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990509"}
{"pmid": "20990502", "title": "PRECOCIOUS puberty.", "content": "PRECOCIOUS puberty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990502"}
{"pmid": "20990510", "title": "Endocrine factors controlling erythrocyte concentration in the blood of the domestic fowl.", "content": "Endocrine factors controlling erythrocyte concentration in the blood of the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990510"}
{"pmid": "20990511", "title": "A study of some effects of sex hormones upon the embryonic reproductive system of the white pekin duck.", "content": "A study of some effects of sex hormones upon the embryonic reproductive system of the white pekin duck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990511"}
{"pmid": "20990501", "title": "CLINICAL use of prostigmin.", "content": "CLINICAL use of prostigmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990501"}
{"pmid": "20990513", "title": "The psychokinetic effect: the first A. S. P. R. experiment.", "content": "The psychokinetic effect: the first A. S. P. R. experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990513"}
{"pmid": "20990520", "title": "Success in ESP as related to form of response drawings; clairvoyance experiments.", "content": "Success in ESP as related to form of response drawings; clairvoyance experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990520"}
{"pmid": "20990521", "title": "On the nature of psi phenomena.", "content": "On the nature of psi phenomena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990521"}
{"pmid": "20990522", "title": "Hypnotic suggestion in PK tests.", "content": "Hypnotic suggestion in PK tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990522"}
{"pmid": "20990523", "title": "The Army's use of psychology during the war.", "content": "The Army's use of psychology during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990523"}
{"pmid": "20990524", "title": "Unfit on psychiatric grounds.", "content": "Unfit on psychiatric grounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990524"}
{"pmid": "20990525", "title": "The influence of the war on juvenile and adolescent vocational interests.", "content": "The influence of the war on juvenile and adolescent vocational interests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990525"}
{"pmid": "20990516", "title": "Developments in occupational classification.", "content": "Developments in occupational classification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990516"}
{"pmid": "20990526", "title": "A note on professional standards for psychologists in Australia.", "content": "A note on professional standards for psychologists in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990526"}
{"pmid": "20990527", "title": "Preliminary studies of the Rorschach records of the Nazi war criminals.", "content": "Preliminary studies of the Rorschach records of the Nazi war criminals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990527"}
{"pmid": "20990518", "title": "Professional status and training of psychologists; report on annual meeting of NYSAAP.", "content": "Professional status and training of psychologists; report on annual meeting of NYSAAP.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990518"}
{"pmid": "20990528", "title": "An experiment with a self-administering form of the Rorschach and group administration by examiners without Rorschach training.", "content": "An experiment with a self-administering form of the Rorschach and group administration by examiners without Rorschach training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990528"}
{"pmid": "20990529", "title": "Non-reading as an expression of resistance.", "content": "Non-reading as an expression of resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990529"}
{"pmid": "20990514", "title": "American social psychology and the war.", "content": "American social psychology and the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990514"}
{"pmid": "20990517", "title": "Adaptation of the Minnesota Multiphasic Personality Inventory for group administration and rapid scoring.", "content": "Adaptation of the Minnesota Multiphasic Personality Inventory for group administration and rapid scoring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990517"}
{"pmid": "20990519", "title": "On certain misuses of the Wechsler-Bellevue scales.", "content": "On certain misuses of the Wechsler-Bellevue scales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990519"}
{"pmid": "20990515", "title": "Military training and the useful parts of learning theory.", "content": "Military training and the useful parts of learning theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990515"}
{"pmid": "20990530", "title": "Rationale for routine Rorschach testing the limits.", "content": "Rationale for routine Rorschach testing the limits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990530"}
{"pmid": "20990531", "title": "School health service in England and Wales.", "content": "School health service in England and Wales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990531"}
{"pmid": "20990532", "title": "Penicillin and streptomycin.", "content": "Penicillin and streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990532"}
{"pmid": "20990533", "title": "The challenge to the voluntary health agency.", "content": "The challenge to the voluntary health agency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990533"}
{"pmid": "20990534", "title": "Infectiousness of the closed case of tuberculosis.", "content": "Infectiousness of the closed case of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990534"}
{"pmid": "20990535", "title": "Hematuria due to picric acid poisoning at a naval anchorage in Japan.", "content": "Hematuria due to picric acid poisoning at a naval anchorage in Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990535"}
{"pmid": "20990536", "title": "Teaching of public health statistics.", "content": "Teaching of public health statistics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990536"}
{"pmid": "20990537", "title": "Use of a potassium tellurite medium in the detection of Corynebacterium diphtheriae.", "content": "Use of a potassium tellurite medium in the detection of Corynebacterium diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990537"}
{"pmid": "20990538", "title": "Realignment of public health nursing services.", "content": "Realignment of public health nursing services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990538"}
{"pmid": "20990539", "title": "Venereal diseases found in Selective Service registrants.", "content": "Venereal diseases found in Selective Service registrants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990539"}
{"pmid": "20990540", "title": "Afebrile parasitemia in imported vivax malaria.", "content": "Afebrile parasitemia in imported vivax malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990540"}
{"pmid": "20990541", "title": "Health, education and security; some post-war perspectives.", "content": "Health, education and security; some post-war perspectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990541"}
{"pmid": "20990542", "title": "Medical service plans across the country.", "content": "Medical service plans across the country.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990542"}
{"pmid": "20990543", "title": "Milk-borne disease in Massachusetts, 1941-1945.", "content": "Milk-borne disease in Massachusetts, 1941-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990543"}
{"pmid": "20990544", "title": "THREE health education projects; a critical analysis.", "content": "THREE health education projects; a critical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990544"}
{"pmid": "20990545", "title": "The first year's work of the Assistant Director of Welfare for Medical Care.", "content": "The first year's work of the Assistant Director of Welfare for Medical Care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990545"}
{"pmid": "20990546", "title": "Penicillin, the miraculous healer.", "content": "Penicillin, the miraculous healer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990546"}
{"pmid": "20990548", "title": "Intra-abdominal surgical technic.", "content": "Intra-abdominal surgical technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990548"}
{"pmid": "20990550", "title": "Prevention of tuberculosis through B. C. G. vaccination.", "content": "Prevention of tuberculosis through B. C. G. vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990550"}
{"pmid": "20990551", "title": "Surgical treatment of glaucoma in aphakic eyes.", "content": "Surgical treatment of glaucoma in aphakic eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990551"}
{"pmid": "20990554", "title": "Presidential address.", "content": "Presidential address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990554"}
{"pmid": "20990555", "title": "The world health organization of the future.", "content": "The world health organization of the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990555"}
{"pmid": "20990556", "title": "International statistical needs of public health.", "content": "International statistical needs of public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990556"}
{"pmid": "20990557", "title": "More health for Canada.", "content": "More health for Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990557"}
{"pmid": "20990558", "title": "Social medicine.", "content": "Social medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990558"}
{"pmid": "20990559", "title": "An outbreak of typhoid fever traced to a wedding breakfast.", "content": "An outbreak of typhoid fever traced to a wedding breakfast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990559"}
{"pmid": "20990560", "title": "Public health nursing in the control of syphilis and gonorrhea.", "content": "Public health nursing in the control of syphilis and gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990560"}
{"pmid": "20990561", "title": "Chronic case care by public health nurses.", "content": "Chronic case care by public health nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990561"}
{"pmid": "20990562", "title": "Food poisoning.", "content": "Food poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990562"}
{"pmid": "20990563", "title": "The x-ray clinic in action.", "content": "The x-ray clinic in action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990563"}
{"pmid": "20990564", "title": "Pupils or people?", "content": "Pupils or people?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990564"}
{"pmid": "20990565", "title": "Anaemia and poverty.", "content": "Anaemia and poverty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990565"}
{"pmid": "20990566", "title": "ASSESSMENT of sex education.", "content": "ASSESSMENT of sex education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990566"}
{"pmid": "20990567", "title": "Children's play.", "content": "Children's play.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990567"}
{"pmid": "20990568", "title": "Hormones.", "content": "Hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990568"}
{"pmid": "20990569", "title": "Health education in the training colleges.", "content": "Health education in the training colleges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990569"}
{"pmid": "20990570", "title": "Social factors and mental health; the latency period of childhood.", "content": "Social factors and mental health; the latency period of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990570"}
{"pmid": "20990571", "title": "Health services in Sweden.", "content": "Health services in Sweden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990571"}
{"pmid": "20990572", "title": "Health education of the pregnant woman.", "content": "Health education of the pregnant woman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990572"}
{"pmid": "20990573", "title": "Educating the asocial.", "content": "Educating the asocial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990573"}
{"pmid": "20990574", "title": "The control of tuberculosis in the veteran.", "content": "The control of tuberculosis in the veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990574"}
{"pmid": "20990575", "title": "Rehabilitation of British industry's neurosis cases.", "content": "Rehabilitation of British industry's neurosis cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990575"}
{"pmid": "20990576", "title": "Brucellosis in swine.", "content": "Brucellosis in swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990576"}
{"pmid": "20990578", "title": "Brucellosis in human beings.", "content": "Brucellosis in human beings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990578"}
{"pmid": "20990577", "title": "Brucellosis in cattle.", "content": "Brucellosis in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990577"}
{"pmid": "20990579", "title": "Growth of Lactobacillus acidophilus in saliva.", "content": "Growth of Lactobacillus acidophilus in saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990579"}
{"pmid": "20990580", "title": "Advantages of the metric system.", "content": "Advantages of the metric system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990580"}
{"pmid": "20990581", "title": "Dermatitis from an annealing compound.", "content": "Dermatitis from an annealing compound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990581"}
{"pmid": "20990582", "title": "Systematic sampling and its relation to other sampling designs.", "content": "Systematic sampling and its relation to other sampling designs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990582"}
{"pmid": "20990583", "title": "Calculating the geometric mean from a large amount of data.", "content": "Calculating the geometric mean from a large amount of data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990583"}
{"pmid": "20990585", "title": "The heating of houses.", "content": "The heating of houses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990585"}
{"pmid": "20990586", "title": "Epidemic disease; past, present and future.", "content": "Epidemic disease; past, present and future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990586"}
{"pmid": "20990584", "title": "The design and analysis of methods for sampling microclimatic factors.", "content": "The design and analysis of methods for sampling microclimatic factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990584"}
{"pmid": "20990587", "title": "The design of relief sewers.", "content": "The design of relief sewers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990587"}
{"pmid": "20990588", "title": "The compulsory notification and treatment of venereal disease; the case for compulsion.", "content": "The compulsory notification and treatment of venereal disease; the case for compulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990588"}
{"pmid": "20990589", "title": "The case against compulsion.", "content": "The case against compulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990589"}
{"pmid": "20990590", "title": "The operation of Regulation 33B.", "content": "The operation of Regulation 33B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990590"}
{"pmid": "20990591", "title": "The National Health Service Bill.", "content": "The National Health Service Bill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990591"}
{"pmid": "20990592", "title": "The use of standard concrete hutting for temporary hospital buildings at Ipswich.", "content": "The use of standard concrete hutting for temporary hospital buildings at Ipswich.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990592"}
{"pmid": "20990593", "title": "The Adoption Acts.", "content": "The Adoption Acts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990593"}
{"pmid": "20990594", "title": "Administrative aspects of the housing problem in Kampala, Uganda.", "content": "Administrative aspects of the housing problem in Kampala, Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990594"}
{"pmid": "20990595", "title": "Tick paralysis.", "content": "Tick paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990595"}
{"pmid": "20990596", "title": "The demands of human nutrition.", "content": "The demands of human nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990596"}
{"pmid": "20990597", "title": "Pertussis immunisation.", "content": "Pertussis immunisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990597"}
{"pmid": "20990601", "title": "Contributions to public health statistics.", "content": "Contributions to public health statistics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990601"}
{"pmid": "20990603", "title": "CONCLUSIONS concerning psychiatric training and clinics.", "content": "CONCLUSIONS concerning psychiatric training and clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990603"}
{"pmid": "20990602", "title": "The public analyst and recent food and drugs legislation.", "content": "The public analyst and recent food and drugs legislation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990602"}
{"pmid": "20990604", "title": "Promizole treatment of leprosy.", "content": "Promizole treatment of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990604"}
{"pmid": "20990599", "title": "Fort Worth, Texas, Negro Health Center.", "content": "Fort Worth, Texas, Negro Health Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990599"}
{"pmid": "20990605", "title": "Present status of diasone in the treatment of leprosy.", "content": "Present status of diasone in the treatment of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990605"}
{"pmid": "20990606", "title": "FOREIGN war brides of American servicemen.", "content": "FOREIGN war brides of American servicemen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990606"}
{"pmid": "20990607", "title": "BALANCE of births and deaths in the war years.", "content": "BALANCE of births and deaths in the war years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990607"}
{"pmid": "20990608", "title": "YOUTHS face a dangerous summer [accident statistics].", "content": "YOUTHS face a dangerous summer [accident statistics].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990608"}
{"pmid": "20990609", "title": "DECLINE in mortality from poliomyelitis.", "content": "DECLINE in mortality from poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990609"}
{"pmid": "20990610", "title": "99 PERCENT drop in typhoid fever mortality.", "content": "99 PERCENT drop in typhoid fever mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990610"}
{"pmid": "20990598", "title": "Distribution of Negro physicians in the United States.", "content": "Distribution of Negro physicians in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990598"}
{"pmid": "20990612", "title": "The use of laminagraphy with encephalography in the diagnosis of midline and subtentorial brain tumors.", "content": "The use of laminagraphy with encephalography in the diagnosis of midline and subtentorial brain tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990612"}
{"pmid": "20990613", "title": "Opaque myelography in penetrating wounds of the spinal canal.", "content": "Opaque myelography in penetrating wounds of the spinal canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990613"}
{"pmid": "20990614", "title": "Subdural pneumography.", "content": "Subdural pneumography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990614"}
{"pmid": "20990615", "title": "Osteochondritis dissecans of the supratrochlear septum of the humerus.", "content": "Osteochondritis dissecans of the supratrochlear septum of the humerus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990615"}
{"pmid": "20990616", "title": "The influence of position on the measurement of the projected bone angle.", "content": "The influence of position on the measurement of the projected bone angle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990616"}
{"pmid": "20990617", "title": "Megaduodenum secondary to an intrinsic duodenal diaphragm; report of case.", "content": "Megaduodenum secondary to an intrinsic duodenal diaphragm; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990617"}
{"pmid": "20990618", "title": "Diverticulum of the cardia of the stomach; report of 3 cases.", "content": "Diverticulum of the cardia of the stomach; report of 3 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990618"}
{"pmid": "20990600", "title": "Improving dentistry in the Negro population.", "content": "Improving dentistry in the Negro population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990600"}
{"pmid": "20990619", "title": "Osteoradionecrosis of the mandible.", "content": "Osteoradionecrosis of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990619"}
{"pmid": "20990620", "title": "Leukosarcoma.", "content": "Leukosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990620"}
{"pmid": "20990621", "title": "Roentgen therapy for malignant teratoma of the testis.", "content": "Roentgen therapy for malignant teratoma of the testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990621"}
{"pmid": "20990622", "title": "The problem of the most efficient therapeutic approach in mediastinal tumor.", "content": "The problem of the most efficient therapeutic approach in mediastinal tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990622"}
{"pmid": "20990623", "title": "A chair for vertical encephalography.", "content": "A chair for vertical encephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990623"}
{"pmid": "20990624", "title": "A method for barium enema examination of the patient with a colostomy.", "content": "A method for barium enema examination of the patient with a colostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990624"}
{"pmid": "20990625", "title": "Blurring in radiography.", "content": "Blurring in radiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990625"}
{"pmid": "20990626", "title": "Untreated carcinoma of the breast.", "content": "Untreated carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990626"}
{"pmid": "20990627", "title": "Note on the maintenance of an x-ray dosage sub-standard.", "content": "Note on the maintenance of an x-ray dosage sub-standard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990627"}
{"pmid": "20990628", "title": "An automatic control for diagnostic x-ray exposures.", "content": "An automatic control for diagnostic x-ray exposures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990628"}
{"pmid": "20990629", "title": "A case of calcinosis circumscripta.", "content": "A case of calcinosis circumscripta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990629"}
{"pmid": "20990630", "title": "Gastro-duodenal invagination.", "content": "Gastro-duodenal invagination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990630"}
{"pmid": "20990631", "title": "A note on the amount of radiation incident in the depths of the pelvis during radiological pelvimetry.", "content": "A note on the amount of radiation incident in the depths of the pelvis during radiological pelvimetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990631"}
{"pmid": "20990632", "title": "Radiotherapeutic treatment of malignant disease.", "content": "Radiotherapeutic treatment of malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990632"}
{"pmid": "20990633", "title": "A short treatise on tropical radiography.", "content": "A short treatise on tropical radiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990633"}
{"pmid": "20990634", "title": "Grave ascending cholangitis following cholangiography carried out through the cystic duct infected with E. coli.", "content": "Grave ascending cholangitis following cholangiography carried out through the cystic duct infected with E. coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990634"}
{"pmid": "20990636", "title": "Histological investigation of the resected sympathetic ganglia in two operated cases of thromboangiitis obliterans, with observations on a number of vascular reactions.", "content": "Histological investigation of the resected sympathetic ganglia in two operated cases of thromboangiitis obliterans, with observations on a number of vascular reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990636"}
{"pmid": "20990637", "title": "Two operated cases of ankylosis cubiti congenita.", "content": "Two operated cases of ankylosis cubiti congenita.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990637"}
{"pmid": "20990638", "title": "Intervertebral foraminotomy.", "content": "Intervertebral foraminotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990638"}
{"pmid": "20990640", "title": "Pelvic single kidney.", "content": "Pelvic single kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990640"}
{"pmid": "20990641", "title": "Carcinoma of the oesophagus, thoracic part, excision, operative cure.", "content": "Carcinoma of the oesophagus, thoracic part, excision, operative cure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990641"}
{"pmid": "20990642", "title": "Fertility in operatively treated and untreated cryptorchidism.", "content": "Fertility in operatively treated and untreated cryptorchidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990642"}
{"pmid": "20990643", "title": "Paraxanthine treatment of hyperthyroidism.", "content": "Paraxanthine treatment of hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990643"}
{"pmid": "20990644", "title": "Clinical experiences with dextran as a plasma substitute.", "content": "Clinical experiences with dextran as a plasma substitute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990644"}
{"pmid": "20990645", "title": "A new method of arthrodesis in arthritis deformans coxae.", "content": "A new method of arthrodesis in arthritis deformans coxae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990645"}
{"pmid": "20990647", "title": "A case of bilateral habitual luxation in the posterior part of the shoulder-joint.", "content": "A case of bilateral habitual luxation in the posterior part of the shoulder-joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990647"}
{"pmid": "20990646", "title": "Operative treatment of large ventral hernias with metal wire-netting.", "content": "Operative treatment of large ventral hernias with metal wire-netting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990646"}
{"pmid": "20990648", "title": "Old clavicular pseudarthrosis with late appearing neuralgias and vasomotoric disturbances cured by operation.", "content": "Old clavicular pseudarthrosis with late appearing neuralgias and vasomotoric disturbances cured by operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990648"}
{"pmid": "20990664", "title": "The place of the long-term patient in the modern hospital; the use and misuse of hospital beds.", "content": "The place of the long-term patient in the modern hospital; the use and misuse of hospital beds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990664"}
{"pmid": "20990665", "title": "Management of a fracture service in an open hospital.", "content": "Management of a fracture service in an open hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990665"}
{"pmid": "20990666", "title": "The International Society of Surgery.", "content": "The International Society of Surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990666"}
{"pmid": "20990667", "title": "Medical care of the veteran.", "content": "Medical care of the veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990667"}
{"pmid": "20990683", "title": "Suturing in cataract operation; a new technique that employs use of a looped silk suture.", "content": "Suturing in cataract operation; a new technique that employs use of a looped silk suture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990683"}
{"pmid": "20990686", "title": "Lunatumfraktur.", "content": "Lunatumfraktur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990686"}
{"pmid": "20990696", "title": "Vibratory threshold in normal persons and poliomyelitis patients as affected by moist heat and infrared rays.", "content": "Vibratory threshold in normal persons and poliomyelitis patients as affected by moist heat and infrared rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990696"}
{"pmid": "20990698", "title": "Causalgia.", "content": "Causalgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990698"}
{"pmid": "20990697", "title": "Modern physiologic concepts of spinal cord function and poliomyelitis.", "content": "Modern physiologic concepts of spinal cord function and poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990697"}
{"pmid": "20990699", "title": "Physical therapy in small community hospitals.", "content": "Physical therapy in small community hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990699"}
{"pmid": "20990710", "title": "OXYCEL; its clinical use.", "content": "OXYCEL; its clinical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990710"}
{"pmid": "20990711", "title": "EPILEPSY control.", "content": "EPILEPSY control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990711"}
{"pmid": "20990721", "title": "Modern methods for the control of arthropod-transmitted diseases.", "content": "Modern methods for the control of arthropod-transmitted diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990721"}
{"pmid": "20990722", "title": "Some remarks on the nomenclature of the malaria parasites of man.", "content": "Some remarks on the nomenclature of the malaria parasites of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990722"}
{"pmid": "20990712", "title": "On the coprophilic habits of a ciliate, Glaucoma piriformis.", "content": "On the coprophilic habits of a ciliate, Glaucoma piriformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990712"}
{"pmid": "20990723", "title": "Certain experiences with malaria during World War II.", "content": "Certain experiences with malaria during World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990723"}
{"pmid": "20990724", "title": "The malaria of the Andean region of South America.", "content": "The malaria of the Andean region of South America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990724"}
{"pmid": "20990725", "title": "A consideration of the problem of evolution of malarial parasites.", "content": "A consideration of the problem of evolution of malarial parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990725"}
{"pmid": "20990713", "title": "Intradermal test in malaria; controls with normal erythrocyte antigen.", "content": "Intradermal test in malaria; controls with normal erythrocyte antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990713"}
{"pmid": "20990728", "title": "Can one have tuberculosis because one has chest pain?", "content": "Can one have tuberculosis because one has chest pain?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990728"}
{"pmid": "20990729", "title": "What is a cavity of lung and what is its significance?", "content": "What is a cavity of lung and what is its significance?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990729"}
{"pmid": "20990733", "title": "Aneurysm of the renal artery following partial nephrectomy.", "content": "Aneurysm of the renal artery following partial nephrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990733"}
{"pmid": "20990734", "title": "Massive perirenal lipoma with report of case.", "content": "Massive perirenal lipoma with report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990734"}
{"pmid": "20990735", "title": "Pyelitis, ureteritis and cystitis cystica.", "content": "Pyelitis, ureteritis and cystitis cystica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990735"}
{"pmid": "20990736", "title": "The use of alloy stainless steel wire in closing urological wounds.", "content": "The use of alloy stainless steel wire in closing urological wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990736"}
{"pmid": "20990737", "title": "Cystoscopic transureteral extraction of a stone located in the renal pelvis.", "content": "Cystoscopic transureteral extraction of a stone located in the renal pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990737"}
{"pmid": "20990738", "title": "Vaginal ureterolithotomy.", "content": "Vaginal ureterolithotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990738"}
{"pmid": "20990739", "title": "A hook for removing foreign bodies from the bladder.", "content": "A hook for removing foreign bodies from the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990739"}
{"pmid": "20990740", "title": "Gunshot wounds of the urinary bladder in wartime.", "content": "Gunshot wounds of the urinary bladder in wartime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990740"}
{"pmid": "20990741", "title": "Crush injury syndrome following prolonged tourniquet action.", "content": "Crush injury syndrome following prolonged tourniquet action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990741"}
{"pmid": "20990742", "title": "Primary spindle cell sarcoma of the urinary bladder with solitary metastasis to the heart muscle.", "content": "Primary spindle cell sarcoma of the urinary bladder with solitary metastasis to the heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990742"}
{"pmid": "20990743", "title": "Giant prostate; the largest recorded.", "content": "Giant prostate; the largest recorded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990743"}
{"pmid": "20990744", "title": "Benign prostatic obstruction: a comparison of results following suprapubic, transurethral, and perineal operative procedures.", "content": "Benign prostatic obstruction: a comparison of results following suprapubic, transurethral, and perineal operative procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990744"}
{"pmid": "20990745", "title": "Survival following castration for prostatic cancer.", "content": "Survival following castration for prostatic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990745"}
{"pmid": "20990746", "title": "Endothelioma of the penis.", "content": "Endothelioma of the penis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990746"}
{"pmid": "20990747", "title": "Fibrous cavernositis: further observation with report of 31 additional cases.", "content": "Fibrous cavernositis: further observation with report of 31 additional cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990747"}
{"pmid": "20990748", "title": "The prevention of urinary tract infection following transurethral prostatic resection by combined use of sulfadiazine and penicillin.", "content": "The prevention of urinary tract infection following transurethral prostatic resection by combined use of sulfadiazine and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990748"}
{"pmid": "20990749", "title": "Venous thrombosis and pulmonary emboli in urology.", "content": "Venous thrombosis and pulmonary emboli in urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990749"}
{"pmid": "20990750", "title": "Reduplication of the urethra.", "content": "Reduplication of the urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990750"}
{"pmid": "20990751", "title": "Male fertility as seen in artificial insemination.", "content": "Male fertility as seen in artificial insemination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990751"}
{"pmid": "20990752", "title": "Psychosomatic problems in urology.", "content": "Psychosomatic problems in urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990752"}
{"pmid": "20990761", "title": "Newcastle disease in poultry.", "content": "Newcastle disease in poultry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990761"}
{"pmid": "20990762", "title": "Developments in artificial insemination of dairy cattle.", "content": "Developments in artificial insemination of dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990762"}
{"pmid": "20990763", "title": "Penicillin therapy in mastitis.", "content": "Penicillin therapy in mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990763"}
{"pmid": "20990764", "title": "DDT.", "content": "DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990764"}
{"pmid": "20990765", "title": "Diseases of calves.", "content": "Diseases of calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990765"}
{"pmid": "20990766", "title": "Some hereditary abnormalities of domestic animals.", "content": "Some hereditary abnormalities of domestic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990766"}
{"pmid": "20990767", "title": "Some neurologic derangements of animals.", "content": "Some neurologic derangements of animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990767"}
{"pmid": "20990768", "title": "Vitamin E prevents and cures the stiff-lamb disease.", "content": "Vitamin E prevents and cures the stiff-lamb disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990768"}
{"pmid": "20990774", "title": "Further investigations into immunization of cattle against rinderpest.", "content": "Further investigations into immunization of cattle against rinderpest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990774"}
{"pmid": "20990769", "title": "The veterinarian in a public health programme.", "content": "The veterinarian in a public health programme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990769"}
{"pmid": "20990775", "title": "On the etiology of epizootic or infectious equine abortion.", "content": "On the etiology of epizootic or infectious equine abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990775"}
{"pmid": "20990776", "title": "Avirulent anthrax vaccine.", "content": "Avirulent anthrax vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990776"}
{"pmid": "20990777", "title": "Recent investigations into the toxicity of plants, etc.", "content": "Recent investigations into the toxicity of plants, etc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990777"}
{"pmid": "20990778", "title": "The biological values of the proteins of some South African (whole seed) maize varieties.", "content": "The biological values of the proteins of some South African (whole seed) maize varieties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990778"}
{"pmid": "20990773", "title": "Feeding mineral to swine in Michigan.", "content": "Feeding mineral to swine in Michigan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990773"}
{"pmid": "20990779", "title": "The familial incidence of spontaneous osteopetrosis gallinarum.", "content": "The familial incidence of spontaneous osteopetrosis gallinarum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990779"}
{"pmid": "20990780", "title": "A study of the compressibility of wool, with special reference to South African merino wool.", "content": "A study of the compressibility of wool, with special reference to South African merino wool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990780"}
{"pmid": "20990781", "title": "A survey of avian salmonellosis in Great Britain.", "content": "A survey of avian salmonellosis in Great Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990781"}
{"pmid": "20990782", "title": "Plasma bilirubin in the horse.", "content": "Plasma bilirubin in the horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990782"}
{"pmid": "20990770", "title": "The role of vitamin A in bovine nutrition.", "content": "The role of vitamin A in bovine nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990770"}
{"pmid": "20990771", "title": "Penicillin therapy in veterinary medicine.", "content": "Penicillin therapy in veterinary medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990771"}
{"pmid": "20990784", "title": "BOVINE sterility.", "content": "BOVINE sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990784"}
{"pmid": "20990783", "title": "Preliminary observation on the modification of a strain of Newcastle disease virus by intracerebral passage through ducklings.", "content": "Preliminary observation on the modification of a strain of Newcastle disease virus by intracerebral passage through ducklings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990783"}
{"pmid": "20990772", "title": "A comparative study of cultures of microorganisms involved in chronic colibacillosis in fowl.", "content": "A comparative study of cultures of microorganisms involved in chronic colibacillosis in fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990772"}
{"pmid": "20990785", "title": "Equine infectious anemia in brood mares and their offspring.", "content": "Equine infectious anemia in brood mares and their offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990785"}
{"pmid": "20990786", "title": "PRESENT day horse practice.", "content": "PRESENT day horse practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990786"}
{"pmid": "20990787", "title": "DISEASE of baby pigs.", "content": "DISEASE of baby pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990787"}
{"pmid": "20990789", "title": "Veterinary practice.", "content": "Veterinary practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990789"}
{"pmid": "20990788", "title": "POULTRY practice.", "content": "POULTRY practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990788"}
{"pmid": "20990790", "title": "Hermaphroditism in a horse.", "content": "Hermaphroditism in a horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990790"}
{"pmid": "20990791", "title": "Abnormal vas deferens constricts intestine in steer.", "content": "Abnormal vas deferens constricts intestine in steer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990791"}
{"pmid": "20990792", "title": "Diabetes mellitus in an English setter.", "content": "Diabetes mellitus in an English setter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990792"}
{"pmid": "20990793", "title": "Ano-vulvar laceration in a mare.", "content": "Ano-vulvar laceration in a mare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990793"}
{"pmid": "20990794", "title": "Fowl typhoid; certain aspects of the experimentally produced disease.", "content": "Fowl typhoid; certain aspects of the experimentally produced disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990794"}
{"pmid": "20990795", "title": "Blood transfusion in the bovine.", "content": "Blood transfusion in the bovine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990795"}
{"pmid": "20990796", "title": "An unusual foetal abnormality.", "content": "An unusual foetal abnormality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990796"}
{"pmid": "20990797", "title": "SHOULD the teaching faculty do research?", "content": "SHOULD the teaching faculty do research?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990797"}
{"pmid": "20990798", "title": "The treatment of mastitis.", "content": "The treatment of mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990798"}
{"pmid": "20990799", "title": "Volvulus in a day-old foal.", "content": "Volvulus in a day-old foal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990799"}
{"pmid": "20990804", "title": "A systematic study of the main arteries in the region of the heart -- Aves XI; Tinamiformes, with some notes on their apparent relationship with the Galliformes.", "content": "A systematic study of the main arteries in the region of the heart -- Aves XI; Tinamiformes, with some notes on their apparent relationship with the Galliformes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990804"}
{"pmid": "20990805", "title": "Protein and fat of the salmon egg as sources of energy for the developing embryo.", "content": "Protein and fat of the salmon egg as sources of energy for the developing embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990805"}
{"pmid": "20990806", "title": "The effects of variations in atmospheric pressure upon insects.", "content": "The effects of variations in atmospheric pressure upon insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990806"}
{"pmid": "20990800", "title": "On the validity of the genotypes designated by Koch (C. L.), 1837-1842, Uebersicht des Arachnidensystems, for genera, the names of which had been first published by that author in 1835-1842, Deutschlands Crustaceen, Myriapoden und Arachniden.", "content": "On the validity of the genotypes designated by Koch (C. L.), 1837-1842, Uebersicht des Arachnidensystems, for genera, the names of which had been first published by that author in 1835-1842, Deutschlands Crustaceen, Myriapoden und Arachniden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990800"}
{"pmid": "20990807", "title": "Parasites, diseases, injuries, and anomalies of the Columbian black-tailed deer, Odocoileus hemionus columbianus (Richardson), in British Columbia.", "content": "Parasites, diseases, injuries, and anomalies of the Columbian black-tailed deer, Odocoileus hemionus columbianus (Richardson), in British Columbia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990807"}
{"pmid": "20990801", "title": "On the type of the genus Diplodinium Schuberg, 1888 (class Ciliophora).", "content": "On the type of the genus Diplodinium Schuberg, 1888 (class Ciliophora).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990801"}
{"pmid": "20990810", "title": "Leucocyte fragility in transitory leucopenia.", "content": "Leucocyte fragility in transitory leucopenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990810"}
{"pmid": "20990809", "title": "Reactions to antipneumococcal rabbit serum; effects of varying amounts of pneumococcal polysaccharide on reversed passive anaphylaxis in guinea pigs; a simple roughly quantitative method of measuring circulating polysaccharide.", "content": "Reactions to antipneumococcal rabbit serum; effects of varying amounts of pneumococcal polysaccharide on reversed passive anaphylaxis in guinea pigs; a simple roughly quantitative method of measuring circulating polysaccharide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990809"}
{"pmid": "20990808", "title": "Reactions to antipneumococcal rabbit serum; failure to adsorb sensitizing antibody by Kieselgur, Fuller's earth, Berkefeld filtrations, and aluminum hydroxide.", "content": "Reactions to antipneumococcal rabbit serum; failure to adsorb sensitizing antibody by Kieselgur, Fuller's earth, Berkefeld filtrations, and aluminum hydroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990808"}
{"pmid": "20990812", "title": "Clinical experiences with a new antihistaminic drug.", "content": "Clinical experiences with a new antihistaminic drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990812"}
{"pmid": "20990814", "title": "The general adaptation syndrome and the diseases of adaptation.", "content": "The general adaptation syndrome and the diseases of adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990814"}
{"pmid": "20990811", "title": "Some antianaphylactic and antihistaminic properties of n'pyridyl, n'benzyl, dimethylethylenediamine monohydrochloride (pyribenzamine).", "content": "Some antianaphylactic and antihistaminic properties of n'pyridyl, n'benzyl, dimethylethylenediamine monohydrochloride (pyribenzamine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990811"}
{"pmid": "20990813", "title": "Histamine antagonists; summary of developments in nonspecific inhibition of histamine, anaphylaxis, and allergy.", "content": "Histamine antagonists; summary of developments in nonspecific inhibition of histamine, anaphylaxis, and allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990813"}
{"pmid": "20990815", "title": "Is the concept of the anatomical position still tenable? a contribution to the subject of anatomical nomenclature.", "content": "Is the concept of the anatomical position still tenable? a contribution to the subject of anatomical nomenclature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990815"}
{"pmid": "20990803", "title": "On the type of the genus Diplodinium Schuberg, 1888 (class Ciliophora).", "content": "On the type of the genus Diplodinium Schuberg, 1888 (class Ciliophora).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990803"}
{"pmid": "20990816", "title": "In vivo staining and retardation of growth of sarcomata in mice.", "content": "In vivo staining and retardation of growth of sarcomata in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990816"}
{"pmid": "20990802", "title": "On Professor Charles A. Koíoid's Application relating to the type of the genus Diplodinium Schuberg, 1888 (class Ciliophora).", "content": "On Professor Charles A. Koíoid's Application relating to the type of the genus Diplodinium Schuberg, 1888 (class Ciliophora).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990802"}
{"pmid": "20990817", "title": "Further investigations on the effect of the male sex hormone on endochondral ossification.", "content": "Further investigations on the effect of the male sex hormone on endochondral ossification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990817"}
{"pmid": "20990818", "title": "Method of duplicating anatomical specimens.", "content": "Method of duplicating anatomical specimens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990818"}
{"pmid": "20990819", "title": "A comparison of growth, differentiation, activity and action currents of heart and skeletal muscle in tissue culture.", "content": "A comparison of growth, differentiation, activity and action currents of heart and skeletal muscle in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990819"}
{"pmid": "20990820", "title": "The day to day level of estrogen and progestin during lactation in the mouse.", "content": "The day to day level of estrogen and progestin during lactation in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990820"}
{"pmid": "20990822", "title": "The amoeboid movement of the mammalian leukocyte in tissue culture.", "content": "The amoeboid movement of the mammalian leukocyte in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990822"}
{"pmid": "20990821", "title": "The intracellular distribution of alkaline phosphatase activity following various methods of histologic fixation.", "content": "The intracellular distribution of alkaline phosphatase activity following various methods of histologic fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990821"}
{"pmid": "20990823", "title": "Glycogen and phosphatase in the developing hair.", "content": "Glycogen and phosphatase in the developing hair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990823"}
{"pmid": "20990824", "title": "The development of the pituitary of the laboratory mouse.", "content": "The development of the pituitary of the laboratory mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990824"}
{"pmid": "20990825", "title": "On the origin of the acrosome and the behaviour of the nebenkern in Diestrammena sp.", "content": "On the origin of the acrosome and the behaviour of the nebenkern in Diestrammena sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990825"}
{"pmid": "20990826", "title": "Studies on the structure, development, and physiology of the nephridia of Oligochaeta; the enteronephric type of nephridial system in earthworms belonging to three species of Megascolex Templeton and three species of Travoscolides Gates (Megascolides McCoy).", "content": "Studies on the structure, development, and physiology of the nephridia of Oligochaeta; the enteronephric type of nephridial system in earthworms belonging to three species of Megascolex Templeton and three species of Travoscolides Gates (Megascolides McCoy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990826"}
{"pmid": "20990827", "title": "Development of olfactory organ in Rana nigromaculata.", "content": "Development of olfactory organ in Rana nigromaculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990827"}
{"pmid": "20990828", "title": "Morphological observations on the fate of the lateral appendix in the embryonic olfactory organ of Rana nigromaculata.", "content": "Morphological observations on the fate of the lateral appendix in the embryonic olfactory organ of Rana nigromaculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990828"}
{"pmid": "20990829", "title": "Further observations on Amoeba discoides.", "content": "Further observations on Amoeba discoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990829"}
{"pmid": "20990830", "title": "Anthropometric study on the Bapende and Basuku of the Belgian Congo.", "content": "Anthropometric study on the Bapende and Basuku of the Belgian Congo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990830"}
{"pmid": "20990831", "title": "Somatotypes of an adolescent group.", "content": "Somatotypes of an adolescent group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990831"}
{"pmid": "20990832", "title": "Symmetrical and asymmetrical occurrence of papillary patterns.", "content": "Symmetrical and asymmetrical occurrence of papillary patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990832"}
{"pmid": "20990833", "title": "The significance of the premaxillary diastema in Pithecanthropus robustus (skull IV).", "content": "The significance of the premaxillary diastema in Pithecanthropus robustus (skull IV).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990833"}
{"pmid": "20990834", "title": "Maxillary diastema as a criterion of generic distinction.", "content": "Maxillary diastema as a criterion of generic distinction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990834"}
{"pmid": "20990835", "title": "On the incidence of the foramen of Civinini and the porus crotaphiticobuccinatorius in American whites and Negroes; observations on 1544 skulls.", "content": "On the incidence of the foramen of Civinini and the porus crotaphiticobuccinatorius in American whites and Negroes; observations on 1544 skulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990835"}
{"pmid": "20990836", "title": "The volume of the sacral canal.", "content": "The volume of the sacral canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990836"}
{"pmid": "20990837", "title": "A method for assessing the development of the hand skeleton.", "content": "A method for assessing the development of the hand skeleton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990837"}
{"pmid": "20990838", "title": "Some factors in the mechanism of sex-determination.", "content": "Some factors in the mechanism of sex-determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990838"}
{"pmid": "20990839", "title": "Transplantation of developing teeth.", "content": "Transplantation of developing teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990839"}
{"pmid": "20990840", "title": "Growth of Mexican infants born in the United States and Mexico.", "content": "Growth of Mexican infants born in the United States and Mexico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990840"}
{"pmid": "20990841", "title": "The amputation prosthesis; a new field for dynamical physical anthropology.", "content": "The amputation prosthesis; a new field for dynamical physical anthropology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990841"}
{"pmid": "20990842", "title": "Constitutional obesity.", "content": "Constitutional obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990842"}
{"pmid": "20990843", "title": "Anthropometric instruments.", "content": "Anthropometric instruments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990843"}
{"pmid": "20990845", "title": "Anthropology of the Arab Bedouin.", "content": "Anthropology of the Arab Bedouin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990845"}
{"pmid": "20990844", "title": "The problem of defining physical ethnic traits in the individual.", "content": "The problem of defining physical ethnic traits in the individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990844"}
{"pmid": "20990846", "title": "Observations on the skeleton of the gorilla.", "content": "Observations on the skeleton of the gorilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990846"}
{"pmid": "20990847", "title": "Dermatoglyphics of the gorilla.", "content": "Dermatoglyphics of the gorilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990847"}
{"pmid": "20990848", "title": "The hand and foot musculature of catarrhine primates; a phylogenetic survey.", "content": "The hand and foot musculature of catarrhine primates; a phylogenetic survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990848"}
{"pmid": "20990849", "title": "Ontogenetic aspects of sutures in man.", "content": "Ontogenetic aspects of sutures in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990849"}
{"pmid": "20990850", "title": "Hiatus canalis sacralis in American whites and Negroes.", "content": "Hiatus canalis sacralis in American whites and Negroes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990850"}
{"pmid": "20990862", "title": "The making of a parasitologist.", "content": "The making of a parasitologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990862"}
{"pmid": "20990851", "title": "On the action of sulfanilamide; the mechanism of action of sulfanilamide derivatives in vitro.", "content": "On the action of sulfanilamide; the mechanism of action of sulfanilamide derivatives in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990851"}
{"pmid": "20990857", "title": "A filtrable virus as a causative agent of epidemic hepatitis.", "content": "A filtrable virus as a causative agent of epidemic hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990857"}
{"pmid": "20990852", "title": "Vi-antigen in B. coli and Vi-agglutinin.", "content": "Vi-antigen in B. coli and Vi-agglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990852"}
{"pmid": "20990863", "title": "Pseudoparasitism of the human intestinal tract.", "content": "Pseudoparasitism of the human intestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990863"}
{"pmid": "20990856", "title": "An improvement in the bactotryptone-sodium formate medium for the detection of B. coli.", "content": "An improvement in the bactotryptone-sodium formate medium for the detection of B. coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990856"}
{"pmid": "20990864", "title": "Studies on Trichomonas gallinae infections in pigeon squabs.", "content": "Studies on Trichomonas gallinae infections in pigeon squabs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990864"}
{"pmid": "20990853", "title": "The classification of the plague-bacillus.", "content": "The classification of the plague-bacillus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990853"}
{"pmid": "20990866", "title": "Helminths of armadillos, Dasypus novemcinctus, in eastern Texas.", "content": "Helminths of armadillos, Dasypus novemcinctus, in eastern Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990866"}
{"pmid": "20990865", "title": "Pinworm (E. vermicularis) and other intestinal parasites in Costa Rican children.", "content": "Pinworm (E. vermicularis) and other intestinal parasites in Costa Rican children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990865"}
{"pmid": "20990854", "title": "A phenomenon resembling anaphylactic shock after treatment with sulphapyridine.", "content": "A phenomenon resembling anaphylactic shock after treatment with sulphapyridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990854"}
{"pmid": "20990860", "title": "The antigenic properties of bacterial spores.", "content": "The antigenic properties of bacterial spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990860"}
{"pmid": "20990867", "title": "Observations on the anatomy of Mesocestoides.", "content": "Observations on the anatomy of Mesocestoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990867"}
{"pmid": "20990868", "title": "The use of mixed colonies of termites in the study of host-symbiont relations.", "content": "The use of mixed colonies of termites in the study of host-symbiont relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990868"}
{"pmid": "20990869", "title": "The laboratory rearing of the tropical rat mite, Liponyssus bacoti (Hirst).", "content": "The laboratory rearing of the tropical rat mite, Liponyssus bacoti (Hirst).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990869"}
{"pmid": "20990870", "title": "Studies on the life history and development of Moniliformis dubius Meyer, 1933.", "content": "Studies on the life history and development of Moniliformis dubius Meyer, 1933.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990870"}
{"pmid": "20990859", "title": "On the preparation of vaccine against typhus fever and the experiences gathered therewith.", "content": "On the preparation of vaccine against typhus fever and the experiences gathered therewith.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990859"}
{"pmid": "20990871", "title": "The migration of infective larvae of Wuchereria bancrofti within the mosquito host and their rate of escape under laboratory conditions.", "content": "The migration of infective larvae of Wuchereria bancrofti within the mosquito host and their rate of escape under laboratory conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990871"}
{"pmid": "20990872", "title": "Cercaria oregonensis, n. sp., a dermatitis-producing schistosome Cercaria from the Pacific Northwest.", "content": "Cercaria oregonensis, n. sp., a dermatitis-producing schistosome Cercaria from the Pacific Northwest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990872"}
{"pmid": "20990873", "title": "The genus Neoschöngastia (Acarinida: Trombiculidae) in the Western Pacific area.", "content": "The genus Neoschöngastia (Acarinida: Trombiculidae) in the Western Pacific area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990873"}
{"pmid": "20990874", "title": "Parasitic hybridization as a cause of cancer.", "content": "Parasitic hybridization as a cause of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990874"}
{"pmid": "20990875", "title": "Some physical properties of the vacuolar membranes in Pelomyxa carolinensis.", "content": "Some physical properties of the vacuolar membranes in Pelomyxa carolinensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990875"}
{"pmid": "20990876", "title": "Patterns of sexual reproductive cycles in ciliates.", "content": "Patterns of sexual reproductive cycles in ciliates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990876"}
{"pmid": "20990881", "title": "Influence of over-ventilation on the cardiovascular reflexes of carotid sinus origin.", "content": "Influence of over-ventilation on the cardiovascular reflexes of carotid sinus origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990881"}
{"pmid": "20990882", "title": "Protection against acceleratory forces by CO2 inhalation.", "content": "Protection against acceleratory forces by CO2 inhalation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990882"}
{"pmid": "20990883", "title": "The Food and Nutrition Board of the National Research Council; a review of some of its accomplishments and a forecast of its future.", "content": "The Food and Nutrition Board of the National Research Council; a review of some of its accomplishments and a forecast of its future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990883"}
{"pmid": "20990884", "title": "International food-evaluation activities and problems.", "content": "International food-evaluation activities and problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990884"}
{"pmid": "20990885", "title": "Nutritional aspects of the milk supply.", "content": "Nutritional aspects of the milk supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990885"}
{"pmid": "20990886", "title": "Human dietary allowances.", "content": "Human dietary allowances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990886"}
{"pmid": "20990887", "title": "The significance and limitations of food composition tables.", "content": "The significance and limitations of food composition tables.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990887"}
{"pmid": "20990888", "title": "Therapeutic applications of chemical warfare agents.", "content": "Therapeutic applications of chemical warfare agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990888"}
{"pmid": "20990889", "title": "Insecticides and rodenticides.", "content": "Insecticides and rodenticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990889"}
{"pmid": "20990890", "title": "Chemotherapy of malaria, 1941-45.", "content": "Chemotherapy of malaria, 1941-45.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990890"}
{"pmid": "20990891", "title": "Bacterial chemotherapy.", "content": "Bacterial chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990891"}
{"pmid": "20990892", "title": "The effect of several levels of dietary calcium and iodine on the basal metabolism of the albino rat during the growth period.", "content": "The effect of several levels of dietary calcium and iodine on the basal metabolism of the albino rat during the growth period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990892"}
{"pmid": "20990893", "title": "Effects of the growth-inhibitor, hexenolactone, on flatworms; absence of axial gradient pattern in the tissue-differential response; chemical mechanism of tissue damage.", "content": "Effects of the growth-inhibitor, hexenolactone, on flatworms; absence of axial gradient pattern in the tissue-differential response; chemical mechanism of tissue damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990893"}
{"pmid": "20990915", "title": "Foreign bodies in and in relation to the thoracic blood vessels and heart; indications for the removal of intracardiac foreign bodies and the behavior of the heart during manipulation.", "content": "Foreign bodies in and in relation to the thoracic blood vessels and heart; indications for the removal of intracardiac foreign bodies and the behavior of the heart during manipulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990915"}
{"pmid": "20990916", "title": "Experiences with dicumarol (3,3' methylene-bis-[4-hydroxycoumarin]) in the treatment of coronary thrombosis with myocardial infarction; preliminary report.", "content": "Experiences with dicumarol (3,3' methylene-bis-[4-hydroxycoumarin]) in the treatment of coronary thrombosis with myocardial infarction; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990916"}
{"pmid": "20990917", "title": "The neurovascular syndrome as manifested in the upper extremities.", "content": "The neurovascular syndrome as manifested in the upper extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990917"}
{"pmid": "20990918", "title": "Potential variations of the right auricular and ventricular cavities in man.", "content": "Potential variations of the right auricular and ventricular cavities in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990918"}
{"pmid": "20990919", "title": "Clinical picture and treatment of the later stage of trench foot.", "content": "Clinical picture and treatment of the later stage of trench foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990919"}
{"pmid": "20990920", "title": "The construction of the cardiac vector.", "content": "The construction of the cardiac vector.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990920"}
{"pmid": "20990921", "title": "The incidence of palpable dorsalis and pedis and posterior tibial pulsations in soldiers; an analysis of over 1,000 infantry soldiers.", "content": "The incidence of palpable dorsalis and pedis and posterior tibial pulsations in soldiers; an analysis of over 1,000 infantry soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990921"}
{"pmid": "20990922", "title": "The rates of water and heat loss from the respiratory tract of patients with congestive heart failure who were from a subtropical climate and resting in a comfortable atmosphere.", "content": "The rates of water and heat loss from the respiratory tract of patients with congestive heart failure who were from a subtropical climate and resting in a comfortable atmosphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990922"}
{"pmid": "20990923", "title": "Wolff-Parkinson-White syndrome; a clinical study with report of nine cases.", "content": "Wolff-Parkinson-White syndrome; a clinical study with report of nine cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990923"}
{"pmid": "20990924", "title": "Transient ventricular fibrillation; report of a case with spontaneous recovery.", "content": "Transient ventricular fibrillation; report of a case with spontaneous recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990924"}
{"pmid": "20990926", "title": "Electrocardiographic features of myocardial infarction as affected by involvement of the septum and by complete and incomplete transmural involvement.", "content": "Electrocardiographic features of myocardial infarction as affected by involvement of the septum and by complete and incomplete transmural involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990926"}
{"pmid": "20990928", "title": "Estimation of heart position from the QRS complex of the electrocardiogram.", "content": "Estimation of heart position from the QRS complex of the electrocardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990928"}
{"pmid": "20990931", "title": "Electrocardiographic abnormalities in severe malnutrition.", "content": "Electrocardiographic abnormalities in severe malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990931"}
{"pmid": "20990932", "title": "The effect of nitrite and exercise on the inverted T wave.", "content": "The effect of nitrite and exercise on the inverted T wave.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990932"}
{"pmid": "20990934", "title": "Pulmonary vascular sclerosis with right ventricular failure.", "content": "Pulmonary vascular sclerosis with right ventricular failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990934"}
{"pmid": "20990933", "title": "Auricular premature systoles: the duration of the electrical systole.", "content": "Auricular premature systoles: the duration of the electrical systole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990933"}
{"pmid": "20990935", "title": "Praecordial electrocardiograms; a comparison of CF and V lead connections.", "content": "Praecordial electrocardiograms; a comparison of CF and V lead connections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990935"}
{"pmid": "20990936", "title": "Bilharzial heart disease in Egypt; cor pulmonale due to bilharzial pulmonary endarteritis.", "content": "Bilharzial heart disease in Egypt; cor pulmonale due to bilharzial pulmonary endarteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990936"}
{"pmid": "20990937", "title": "Mechanism of the Wolff-Parkinson-White syndrome.", "content": "Mechanism of the Wolff-Parkinson-White syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990937"}
{"pmid": "20990938", "title": "Postural hypotension.", "content": "Postural hypotension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990938"}
{"pmid": "20990939", "title": "Cardiovascular diseases in the British Army overseas.", "content": "Cardiovascular diseases in the British Army overseas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990939"}
{"pmid": "20990940", "title": "[ACUTE rheumatic carditis with left heart failure].", "content": "[ACUTE rheumatic carditis with left heart failure].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990940"}
{"pmid": "20990941", "title": "INCIDENCE of the hemolytic streptococcus, group A, in the throats of rheumatic children.", "content": "INCIDENCE of the hemolytic streptococcus, group A, in the throats of rheumatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990941"}
{"pmid": "20990942", "title": "Treatment of subacute bacterial endocarditis.", "content": "Treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990942"}
{"pmid": "20990943", "title": "Phosphorus; creator and destroyer.", "content": "Phosphorus; creator and destroyer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990943"}
{"pmid": "20990944", "title": "The development of insulin.", "content": "The development of insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990944"}
{"pmid": "20990945", "title": "The thermal polymerization of methyl methacrylate.", "content": "The thermal polymerization of methyl methacrylate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990945"}
{"pmid": "20990946", "title": "Equilibrium studies on the dehydrogenation of primary and secondary alcohols; 2-butanol, 2-octanol, cyclopentanol and benzyl alcohol.", "content": "Equilibrium studies on the dehydrogenation of primary and secondary alcohols; 2-butanol, 2-octanol, cyclopentanol and benzyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990946"}
{"pmid": "20990947", "title": "The polarography of uranium; polarography in strongly acid solution.", "content": "The polarography of uranium; polarography in strongly acid solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990947"}
{"pmid": "20990948", "title": "The absorption spectra of some para substituted aniline derivatives; the presence of x bands.", "content": "The absorption spectra of some para substituted aniline derivatives; the presence of x bands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990948"}
{"pmid": "20990949", "title": "The spectrophotometric estimation of methoxy-cinchona alkaloids.", "content": "The spectrophotometric estimation of methoxy-cinchona alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990949"}
{"pmid": "20990950", "title": "Vinyl ethyl ether and other vinyl ethers.", "content": "Vinyl ethyl ether and other vinyl ethers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990950"}
{"pmid": "20990951", "title": "The synthesis of 4-hydroxyquinolines; through ethoxymethylene malonic ester.", "content": "The synthesis of 4-hydroxyquinolines; through ethoxymethylene malonic ester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990951"}
{"pmid": "20990952", "title": "Synthetic antimalarials; the preparation of certain 4-aminoquinolines.", "content": "Synthetic antimalarials; the preparation of certain 4-aminoquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990952"}
{"pmid": "20990953", "title": "Synthetic antimalarials; the preparation and properties of 7-chloro-4-(4-diethylamino-l-methylbutylamino)-quinoline (SN-7618).", "content": "Synthetic antimalarials; the preparation and properties of 7-chloro-4-(4-diethylamino-l-methylbutylamino)-quinoline (SN-7618).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990953"}
{"pmid": "20990954", "title": "The synthesis of some 7-chloro-4-(3-alkylamino-propylamino) quinolines.", "content": "The synthesis of some 7-chloro-4-(3-alkylamino-propylamino) quinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990954"}
{"pmid": "20990955", "title": "The synthesis of 4-(4'-amino-l'-methylbutylamino)-7-chloroquinoline and some 4-(4'-monoalkylamino-l'-methylbutylamino)-7-chloroquinolines.", "content": "The synthesis of 4-(4'-amino-l'-methylbutylamino)-7-chloroquinoline and some 4-(4'-monoalkylamino-l'-methylbutylamino)-7-chloroquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990955"}
{"pmid": "20990956", "title": "Synthesis of monoalkyl-substituted diamines and their condensation products with 4,7-dichloroquinoline.", "content": "Synthesis of monoalkyl-substituted diamines and their condensation products with 4,7-dichloroquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990956"}
{"pmid": "20990957", "title": "The preparation of some 4-aminoquinolines.", "content": "The preparation of some 4-aminoquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990957"}
{"pmid": "20990958", "title": "Synthesis of antimalarials; the synthesis of certain 4-aminoquinoline derivatives.", "content": "Synthesis of antimalarials; the synthesis of certain 4-aminoquinoline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990958"}
{"pmid": "20990959", "title": "The synthesis of 7-chloro-4-(l-ethyl-4-piperidylamino)-quinoline (SN-13,425).", "content": "The synthesis of 7-chloro-4-(l-ethyl-4-piperidylamino)-quinoline (SN-13,425).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990959"}
{"pmid": "20990960", "title": "Quinolines; some Bz-iodo-3-methyl-4-(l'-methyl-4'-diethyl-aminobutylamino)-quinolines.", "content": "Quinolines; some Bz-iodo-3-methyl-4-(l'-methyl-4'-diethyl-aminobutylamino)-quinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990960"}
{"pmid": "20990961", "title": "The preparation of Bz-dichloro-4-aminoquinoline derivatives.", "content": "The preparation of Bz-dichloro-4-aminoquinoline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990961"}
{"pmid": "20990962", "title": "A synthesis of substituted 4-aminoquinolines.", "content": "A synthesis of substituted 4-aminoquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990962"}
{"pmid": "20990963", "title": "Synthesis of certain simple 4-aminoquinoline derivatives.", "content": "Synthesis of certain simple 4-aminoquinoline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990963"}
{"pmid": "20990964", "title": "Synthesis of 4-hydroxyquinolines; preparation through 3-cyano and 3-carbanilido derivatives.", "content": "Synthesis of 4-hydroxyquinolines; preparation through 3-cyano and 3-carbanilido derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990964"}
{"pmid": "20990965", "title": "Synthesis of 4-hydroxyquinolines; a direct synthesis of beta-substituted acrylic esters.", "content": "Synthesis of 4-hydroxyquinolines; a direct synthesis of beta-substituted acrylic esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990965"}
{"pmid": "20990966", "title": "Synthesis of 4-hydroxyquinolines; a modified preparation through bis-(m-chlorophenyl)-formamidine.", "content": "Synthesis of 4-hydroxyquinolines; a modified preparation through bis-(m-chlorophenyl)-formamidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990966"}
{"pmid": "20990967", "title": "Synthesis of 4-hydroxyquinolines; a direct synthesis from beta-anilinoacrylates.", "content": "Synthesis of 4-hydroxyquinolines; a direct synthesis from beta-anilinoacrylates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990967"}
{"pmid": "20990968", "title": "Experiments on the synthesis of 4-hydroxy- and 4-chloroquinolines from beta-anilinopropionic acids.", "content": "Experiments on the synthesis of 4-hydroxy- and 4-chloroquinolines from beta-anilinopropionic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990968"}
{"pmid": "20990969", "title": "The synthesis of some 4-quinolinols and 4-chloroquinolines by the ethoxymethylenemalonic ester method.", "content": "The synthesis of some 4-quinolinols and 4-chloroquinolines by the ethoxymethylenemalonic ester method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990969"}
{"pmid": "20990970", "title": "The decarboxylation of nitro substituted 3-carboxy-4-quinolinols by pyrolysis of their silver salts.", "content": "The decarboxylation of nitro substituted 3-carboxy-4-quinolinols by pyrolysis of their silver salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990970"}
{"pmid": "20990971", "title": "The synthesis of some chloromethoxyquinolines.", "content": "The synthesis of some chloromethoxyquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990971"}
{"pmid": "20990972", "title": "A new synthesis of 2-aryl-4-hydroxyquinolines.", "content": "A new synthesis of 2-aryl-4-hydroxyquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990972"}
{"pmid": "20990973", "title": "Synthesis of 2-phenyl-4-chloroquinolines.", "content": "Synthesis of 2-phenyl-4-chloroquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990973"}
{"pmid": "20990974", "title": "3-phenyl-4-chloro- and 3-phenyl-4,7-dichloroquinoline.", "content": "3-phenyl-4-chloro- and 3-phenyl-4,7-dichloroquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990974"}
{"pmid": "20990975", "title": "The synthesis of 4,6- and 4,8-dichloroquinoline.", "content": "The synthesis of 4,6- and 4,8-dichloroquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990975"}
{"pmid": "20990976", "title": "Synthesis of 4-hydroxyquinolines; synthesis of 3-n-heptyl-7-methoxy-2-methyl-4-quinolinol.", "content": "Synthesis of 4-hydroxyquinolines; synthesis of 3-n-heptyl-7-methoxy-2-methyl-4-quinolinol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990976"}
{"pmid": "20990977", "title": "Synthesis of 4-hydroxyquinolines; 3-(di-n-butylaminomethyl)-7-methoxy-2-methyl-4-quinolinol.", "content": "Synthesis of 4-hydroxyquinolines; 3-(di-n-butylaminomethyl)-7-methoxy-2-methyl-4-quinolinol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990977"}
{"pmid": "20990978", "title": "The synthesis of 3-(3-cyclohexylpropyl)-4-quinolinol.", "content": "The synthesis of 3-(3-cyclohexylpropyl)-4-quinolinol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990978"}
{"pmid": "20990979", "title": "Some 3-alkyl-2,4-quinolinediols.", "content": "Some 3-alkyl-2,4-quinolinediols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990979"}
{"pmid": "20990980", "title": "Antimalarials; the synthesis of 2,4,7-trichloroquinoline.", "content": "Antimalarials; the synthesis of 2,4,7-trichloroquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990980"}
{"pmid": "20990981", "title": "Antimalarials; hydrolysis and methanolysis of 2,4,7-trichloroquinoline.", "content": "Antimalarials; hydrolysis and methanolysis of 2,4,7-trichloroquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990981"}
{"pmid": "20990982", "title": "Synthesis of 1-diethylamino-2,3-epoxypropane, 3-diethylamino-2-hydroxypropylamine, and 4-diethylamino-3-hydroxybutylamine.", "content": "Synthesis of 1-diethylamino-2,3-epoxypropane, 3-diethylamino-2-hydroxypropylamine, and 4-diethylamino-3-hydroxybutylamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990982"}
{"pmid": "20990983", "title": "Synthesis of 1-diethylamino-5-amino hexane.", "content": "Synthesis of 1-diethylamino-5-amino hexane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990983"}
{"pmid": "20990984", "title": "Synthesis of alicyclic diamines.", "content": "Synthesis of alicyclic diamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990984"}
{"pmid": "20990985", "title": "The preparation of some alpha-dialkylamino-omega-methylaminoalkanes.", "content": "The preparation of some alpha-dialkylamino-omega-methylaminoalkanes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990985"}
{"pmid": "20990986", "title": "Quinazoline derivatives; the synthesis of 4-(4'-diethylamino-1'-methylbutylamino)-quinazoline (SN 11,534) and the corresponding 2-phenylquinazoline (SN 11,535).", "content": "Quinazoline derivatives; the synthesis of 4-(4'-diethylamino-1'-methylbutylamino)-quinazoline (SN 11,534) and the corresponding 2-phenylquinazoline (SN 11,535).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990986"}
{"pmid": "20990988", "title": "Quinazoline derivatives; the synthesis of 4-(3'-diethylaminopropoxy)-6-chloroquinazoline (SN 12,254).", "content": "Quinazoline derivatives; the synthesis of 4-(3'-diethylaminopropoxy)-6-chloroquinazoline (SN 12,254).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990988"}
{"pmid": "20990987", "title": "Quinazoline derivatives; synthesis of 4-(4'-diethylamino-1'-methylbutylamino)-6-methoxyquinazoline (SN 12,253).", "content": "Quinazoline derivatives; synthesis of 4-(4'-diethylamino-1'-methylbutylamino)-6-methoxyquinazoline (SN 12,253).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990987"}
{"pmid": "20990989", "title": "4-(4'-diethylamino-l'-methylbutylamino)-7-chloroquinazoline.", "content": "4-(4'-diethylamino-l'-methylbutylamino)-7-chloroquinazoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990989"}
{"pmid": "20990990", "title": "Quinazolines; syntheses of 4-alkylaminoquinazolines.", "content": "Quinazolines; syntheses of 4-alkylaminoquinazolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990990"}
{"pmid": "20990992", "title": "4-Substituted cinnoline derivatives.", "content": "4-Substituted cinnoline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990992"}
{"pmid": "20990991", "title": "Synthetic antimalarials; some 1-(4-diethylamino-l-methyl-butylamino)-isoquinolines.", "content": "Synthetic antimalarials; some 1-(4-diethylamino-l-methyl-butylamino)-isoquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990991"}
{"pmid": "20990993", "title": "Synthetic antimalarials; some 1-(4-diethylamino-1-methylbutylamino)-phthalazines.", "content": "Synthetic antimalarials; some 1-(4-diethylamino-1-methylbutylamino)-phthalazines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990993"}
{"pmid": "20990994", "title": "The preparation of some phthalazines and related substances.", "content": "The preparation of some phthalazines and related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990994"}
{"pmid": "20990995", "title": "Synthesis of antimalarials; synthesis of certain 1,5- and 1,8-naphthyridine derivatives.", "content": "Synthesis of antimalarials; synthesis of certain 1,5- and 1,8-naphthyridine derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990995"}
{"pmid": "20990996", "title": "Some substituted 1,10-phenanthrolines.", "content": "Some substituted 1,10-phenanthrolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990996"}
{"pmid": "20990997", "title": "Antimalarials; dl-7-chloro-2-(4-diethylamino-l-methylbutylamino)-quinoline.", "content": "Antimalarials; dl-7-chloro-2-(4-diethylamino-l-methylbutylamino)-quinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990997"}
{"pmid": "20990998", "title": "Antimalarials; some notes on the attempted synthesis of 7-chloro-6-dialkylaminoalkylaminoquinolines.", "content": "Antimalarials; some notes on the attempted synthesis of 7-chloro-6-dialkylaminoalkylaminoquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990998"}
{"pmid": "20990999", "title": "Antimalarials; 2-chloro-5-(3-diethylaminopropylamino)-quinoline; useful preparations of 2-chloro-5- and 8-nitroquinolines.", "content": "Antimalarials; 2-chloro-5-(3-diethylaminopropylamino)-quinoline; useful preparations of 2-chloro-5- and 8-nitroquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20990999"}
{"pmid": "20991000", "title": "Some gamma-substituted benzoquinoline derivatives.", "content": "Some gamma-substituted benzoquinoline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991000"}
{"pmid": "20991001", "title": "Preparation of 7-chloro-4-(2-piperidylmethylamino)-quinoline.", "content": "Preparation of 7-chloro-4-(2-piperidylmethylamino)-quinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991001"}
{"pmid": "20991002", "title": "Studies in the quinoline series; some derivatives of 4-styrylquinoline.", "content": "Studies in the quinoline series; some derivatives of 4-styrylquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991002"}
{"pmid": "20991003", "title": "The vapor pressures and saturated liquid and vapor densities of the isomeric hexanes.", "content": "The vapor pressures and saturated liquid and vapor densities of the isomeric hexanes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991003"}
{"pmid": "20991004", "title": "The composition, optical and crystallographic properties of two calcium oxalate-chloride double salts.", "content": "The composition, optical and crystallographic properties of two calcium oxalate-chloride double salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991004"}
{"pmid": "20991005", "title": "Heats of polymerization; some esters of alpha-methylacrylic acid.", "content": "Heats of polymerization; some esters of alpha-methylacrylic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991005"}
{"pmid": "20991006", "title": "The dipole moments and structures of ketene and of several polar molecules containing conjugated systems.", "content": "The dipole moments and structures of ketene and of several polar molecules containing conjugated systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991006"}
{"pmid": "20991007", "title": "Alkoxy- and aryloxystyrenes.", "content": "Alkoxy- and aryloxystyrenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991007"}
{"pmid": "20991008", "title": "Pyridines; aldehyde-collidine and 5-ethyl-2-vinylpyridine.", "content": "Pyridines; aldehyde-collidine and 5-ethyl-2-vinylpyridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991008"}
{"pmid": "20991009", "title": "A new anhydride of D-glucose: D-glucosan <1,4>beta<1,6>.", "content": "A new anhydride of D-glucose: D-glucosan <1,4>beta<1,6>.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991009"}
{"pmid": "20991010", "title": "Cyclic thioureas.", "content": "Cyclic thioureas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991010"}
{"pmid": "20991011", "title": "Crystalline vitamin A methyl ether.", "content": "Crystalline vitamin A methyl ether.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991011"}
{"pmid": "20991012", "title": "Micro-analysis of mixtures (amino acids) in the form of isotopic derivatives.", "content": "Micro-analysis of mixtures (amino acids) in the form of isotopic derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991012"}
{"pmid": "20991013", "title": "On the peptide nature of vitamin Bc conjugate from yeast.", "content": "On the peptide nature of vitamin Bc conjugate from yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991013"}
{"pmid": "20991014", "title": "The oxidation of liquid hydrocarbons; the chain formation of hydroperoxides and their decomposition.", "content": "The oxidation of liquid hydrocarbons; the chain formation of hydroperoxides and their decomposition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991014"}
{"pmid": "20991015", "title": "The oxidation of liquid hydrocarbons; the energy-chain mechanism for the thermal oxidation of tetralin.", "content": "The oxidation of liquid hydrocarbons; the energy-chain mechanism for the thermal oxidation of tetralin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991015"}
{"pmid": "20991017", "title": "The prevention of the decalcification of enamel during orthodontic treatment.", "content": "The prevention of the decalcification of enamel during orthodontic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991017"}
{"pmid": "20991016", "title": "The oxidation of liquid hydrocarbons; the oxidation of tetralin in the presence of benzol peroxide as a free radical chain reaction.", "content": "The oxidation of liquid hydrocarbons; the oxidation of tetralin in the presence of benzol peroxide as a free radical chain reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991016"}
{"pmid": "20991018", "title": "The treatment of malocclusions.", "content": "The treatment of malocclusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991018"}
{"pmid": "20991019", "title": "Cephalometric appraisal of a class I (Angle) malocclusion in which four first premolars were extracted as part of the treatment plan.", "content": "Cephalometric appraisal of a class I (Angle) malocclusion in which four first premolars were extracted as part of the treatment plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991019"}
{"pmid": "20991020", "title": "Anesthetic management in reconstructive surgery of the mandible.", "content": "Anesthetic management in reconstructive surgery of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991020"}
{"pmid": "20991021", "title": "Congenital mandibular deformities in newborn infants.", "content": "Congenital mandibular deformities in newborn infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991021"}
{"pmid": "20991022", "title": "Osteotomy for the correction of mandibular protrusion.", "content": "Osteotomy for the correction of mandibular protrusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991022"}
{"pmid": "20991023", "title": "Prosthetic restoration of congenital cleft palate.", "content": "Prosthetic restoration of congenital cleft palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991023"}
{"pmid": "20991024", "title": "Oral defects in their relation to defective speech.", "content": "Oral defects in their relation to defective speech.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991024"}
{"pmid": "20991025", "title": "Bilateral fracture of mandible.", "content": "Bilateral fracture of mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991025"}
{"pmid": "20991026", "title": "Gunshot wounds of jaw.", "content": "Gunshot wounds of jaw.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991026"}
{"pmid": "20991028", "title": "Periodontoclasia.", "content": "Periodontoclasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991028"}
{"pmid": "20991027", "title": "Foreign body, localization.", "content": "Foreign body, localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991027"}
{"pmid": "20991029", "title": "Malocclusion.", "content": "Malocclusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991029"}
{"pmid": "20991030", "title": "Treatment of fractured crowns of anterior teeth in children as practised by Ellis.", "content": "Treatment of fractured crowns of anterior teeth in children as practised by Ellis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991030"}
{"pmid": "20991031", "title": "Presidential address.", "content": "Presidential address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991031"}
{"pmid": "20991032", "title": "Vincent's infection; observations on the histopathology and their application to clinical practice.", "content": "Vincent's infection; observations on the histopathology and their application to clinical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991032"}
{"pmid": "20991033", "title": "Observations on the dental condition of Europeans and Asiatics in Singapore following the Japanese Occupation.", "content": "Observations on the dental condition of Europeans and Asiatics in Singapore following the Japanese Occupation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991033"}
{"pmid": "20991034", "title": "The carious tooth as a portal of entry for poliomyelitis.", "content": "The carious tooth as a portal of entry for poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991034"}
{"pmid": "20991035", "title": "Sharpening of dental instruments.", "content": "Sharpening of dental instruments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991035"}
{"pmid": "20991036", "title": "The surgical correction of alveolar ridges.", "content": "The surgical correction of alveolar ridges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991036"}
{"pmid": "20991037", "title": "A simplified full denture technique.", "content": "A simplified full denture technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991037"}
{"pmid": "20991038", "title": "Eruption of deciduous teeth.", "content": "Eruption of deciduous teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991038"}
{"pmid": "20991039", "title": "The anti-biotic relationship between parodontal disease and dental disintegration.", "content": "The anti-biotic relationship between parodontal disease and dental disintegration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991039"}
{"pmid": "20991040", "title": "Multilocular cyst of the lower jaw.", "content": "Multilocular cyst of the lower jaw.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991040"}
{"pmid": "20991041", "title": "Surgery of the mouth and jaws.", "content": "Surgery of the mouth and jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991041"}
{"pmid": "20991042", "title": "Sarcoma associated with mandibular impacted third molar.", "content": "Sarcoma associated with mandibular impacted third molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991042"}
{"pmid": "20991043", "title": "Trismus and tumor associated with impacted third molar.", "content": "Trismus and tumor associated with impacted third molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991043"}
{"pmid": "20991044", "title": "Cast gold inlays for porcelain teeth.", "content": "Cast gold inlays for porcelain teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991044"}
{"pmid": "20991045", "title": "Nutrition and dental health.", "content": "Nutrition and dental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991045"}
{"pmid": "20991046", "title": "The importance of dental hygiene as a cancer control measure.", "content": "The importance of dental hygiene as a cancer control measure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991046"}
{"pmid": "20991047", "title": "Modern dental office anaesthesia.", "content": "Modern dental office anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991047"}
{"pmid": "20991048", "title": "The group movement in Great Britain.", "content": "The group movement in Great Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991048"}
{"pmid": "20991049", "title": "Mandibular osteomyelitis: its diagnosis and treatment.", "content": "Mandibular osteomyelitis: its diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991049"}
{"pmid": "20991051", "title": "Cancer of the oral mucosa and circum-oral areas.", "content": "Cancer of the oral mucosa and circum-oral areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991051"}
{"pmid": "20991052", "title": "Dental practice management.", "content": "Dental practice management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991052"}
{"pmid": "20991054", "title": "Penicillin as an oral therapeutic agent.", "content": "Penicillin as an oral therapeutic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991054"}
{"pmid": "20991053", "title": "Starvation diets and their effects upon the mouth.", "content": "Starvation diets and their effects upon the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991053"}
{"pmid": "20991055", "title": "Recent developments in fuso-spirochetal and related infections: the role of infection in Vincent's and related diseases.", "content": "Recent developments in fuso-spirochetal and related infections: the role of infection in Vincent's and related diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991055"}
{"pmid": "20991056", "title": "Nutrition and dental health; mineral availability and utilization; summary of dietary needs and recommendations.", "content": "Nutrition and dental health; mineral availability and utilization; summary of dietary needs and recommendations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991056"}
{"pmid": "20991066", "title": "An aeration apparatus for the estimation of blood bromides.", "content": "An aeration apparatus for the estimation of blood bromides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991066"}
{"pmid": "20991067", "title": "Practical aspects of the Rh factor.", "content": "Practical aspects of the Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991067"}
{"pmid": "20991068", "title": "Chronic myelogenous leukemia; a case report.", "content": "Chronic myelogenous leukemia; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991068"}
{"pmid": "20991058", "title": "Maxillo-facial prosthesis.", "content": "Maxillo-facial prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991058"}
{"pmid": "20991057", "title": "Definitive treatment of maxillo-facial injuries.", "content": "Definitive treatment of maxillo-facial injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991057"}
{"pmid": "20991069", "title": "Laboratory aids in the diagnosis and treatment of tuberculosis.", "content": "Laboratory aids in the diagnosis and treatment of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991069"}
{"pmid": "20991070", "title": "Studies on selective staining of collagen with acid anilin dyes.", "content": "Studies on selective staining of collagen with acid anilin dyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991070"}
{"pmid": "20991071", "title": "The utility of the vaginal smear technique.", "content": "The utility of the vaginal smear technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991071"}
{"pmid": "20991072", "title": "Fixation of tissues by perfusion technique.", "content": "Fixation of tissues by perfusion technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991072"}
{"pmid": "20991073", "title": "A modification of the giemsa strain for malarial parasites.", "content": "A modification of the giemsa strain for malarial parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991073"}
{"pmid": "20991074", "title": "Staining racks of three designs for coverglass preparations.", "content": "Staining racks of three designs for coverglass preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991074"}
{"pmid": "20991075", "title": "A note on stored formaldehyde and its easy reconditioning.", "content": "A note on stored formaldehyde and its easy reconditioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991075"}
{"pmid": "20991076", "title": "A method for the removal of precipitate from tissues fixed in formaldehyde.", "content": "A method for the removal of precipitate from tissues fixed in formaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991076"}
{"pmid": "20991077", "title": "Smear methods for mammalian tissues, including tumors.", "content": "Smear methods for mammalian tissues, including tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991077"}
{"pmid": "20991078", "title": "A reliable Nissl method.", "content": "A reliable Nissl method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991078"}
{"pmid": "20991079", "title": "Lucite in museum work.", "content": "Lucite in museum work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991079"}
{"pmid": "20991080", "title": "J. J. Woodward and photomicrography during the Civil War.", "content": "J. J. Woodward and photomicrography during the Civil War.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991080"}
{"pmid": "20991081", "title": "The museum and the historical novel.", "content": "The museum and the historical novel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991081"}
{"pmid": "20991082", "title": "Rubber moulages for first aid training.", "content": "Rubber moulages for first aid training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991082"}
{"pmid": "20991083", "title": "The classification and cross indexing of pathological material by means of a chart adaption of the Standard Nomenclature of Disease.", "content": "The classification and cross indexing of pathological material by means of a chart adaption of the Standard Nomenclature of Disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991083"}
{"pmid": "20991084", "title": "Intestinal diseases in the Japanese prison camps in the Philippines.", "content": "Intestinal diseases in the Japanese prison camps in the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991084"}
{"pmid": "20991085", "title": "Review of the autopsy service in a small rural hospital.", "content": "Review of the autopsy service in a small rural hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991085"}
{"pmid": "20991086", "title": "The nutritional improvement of life.", "content": "The nutritional improvement of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991086"}
{"pmid": "20991087", "title": "Human starvation and its consequences.", "content": "Human starvation and its consequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991087"}
{"pmid": "20991089", "title": "Adequacy of the diet during lactation.", "content": "Adequacy of the diet during lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991089"}
{"pmid": "20991088", "title": "Nutritional status during pregnancy and after delivery of a group of women in Mexico City.", "content": "Nutritional status during pregnancy and after delivery of a group of women in Mexico City.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991088"}
{"pmid": "20991090", "title": "LIBERAL infant feeding.", "content": "LIBERAL infant feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991090"}
{"pmid": "20991091", "title": "Vitamin content of frozen peas, green beans and lima beans, and market-fresh yams prepared in a Navy mess hall.", "content": "Vitamin content of frozen peas, green beans and lima beans, and market-fresh yams prepared in a Navy mess hall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991091"}
{"pmid": "20991092", "title": "Educational programs in a Veterans Administration hospital.", "content": "Educational programs in a Veterans Administration hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991092"}
{"pmid": "20991093", "title": "Nutrition surveys in Arizona.", "content": "Nutrition surveys in Arizona.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991093"}
{"pmid": "20991094", "title": "FAMINE emergency program of the American Red Cross.", "content": "FAMINE emergency program of the American Red Cross.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991094"}
{"pmid": "20991095", "title": "Dietary requirements in human pregnancy and lactation; a review of recent work.", "content": "Dietary requirements in human pregnancy and lactation; a review of recent work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991095"}
{"pmid": "20991096", "title": "The incidence of gastrointestinal disorders; from a study of 2,839 cases.", "content": "The incidence of gastrointestinal disorders; from a study of 2,839 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991096"}
{"pmid": "20991097", "title": "Regional enteritis in Puerto Rico.", "content": "Regional enteritis in Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991097"}
{"pmid": "20991098", "title": "Epidemiological study of an outbreak of infectious hepatitis.", "content": "Epidemiological study of an outbreak of infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991098"}
{"pmid": "20991099", "title": "Chronic gastritis; observations on its course and significance.", "content": "Chronic gastritis; observations on its course and significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991099"}
{"pmid": "20991100", "title": "Results of high caloric feeding.", "content": "Results of high caloric feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991100"}
{"pmid": "20991101", "title": "Problems in the etiology of peptic ulcer; the resistance of the gastrointestinal tract to the digestive action of its own secretions.", "content": "Problems in the etiology of peptic ulcer; the resistance of the gastrointestinal tract to the digestive action of its own secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991101"}
{"pmid": "20991102", "title": "Things to do if cancer of the stomach is oftener to be cured; report of an instructive case.", "content": "Things to do if cancer of the stomach is oftener to be cured; report of an instructive case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991102"}
{"pmid": "20991103", "title": "The consistency, opacity, and columnar cell content of gastric mucus secreted under the influence of several mild irritants.", "content": "The consistency, opacity, and columnar cell content of gastric mucus secreted under the influence of several mild irritants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991103"}
{"pmid": "20991104", "title": "Isolated Hodgkin's disease of the stomach.", "content": "Isolated Hodgkin's disease of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991104"}
{"pmid": "20991105", "title": "Anti-ulcer (anthelone) products in the treatment of peptic ulcer.", "content": "Anti-ulcer (anthelone) products in the treatment of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991105"}
{"pmid": "20991109", "title": "Modification of the frequency of chromosomal rearrangements induced by x-rays in Drosophila; use of near infrared radiation.", "content": "Modification of the frequency of chromosomal rearrangements induced by x-rays in Drosophila; use of near infrared radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991109"}
{"pmid": "20991110", "title": "Modification of the frequency of chromosomal rearrangements induced by x-rays in Drosophila; use of ultraviolet radiation.", "content": "Modification of the frequency of chromosomal rearrangements induced by x-rays in Drosophila; use of ultraviolet radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991110"}
{"pmid": "20991111", "title": "Spontaneous mutation at the R locus in maize; the aleurone-color and plant-color effects.", "content": "Spontaneous mutation at the R locus in maize; the aleurone-color and plant-color effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991111"}
{"pmid": "20991106", "title": "Current problems in medico-legal testimony.", "content": "Current problems in medico-legal testimony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991106"}
{"pmid": "20991112", "title": "Dominigenes of the vestigial series in Drosophila melanogaster.", "content": "Dominigenes of the vestigial series in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991112"}
{"pmid": "20991113", "title": "Inheritance in Nicotiana tabacum; the mechanism of chromosome substitution.", "content": "Inheritance in Nicotiana tabacum; the mechanism of chromosome substitution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991113"}
{"pmid": "20991114", "title": "Phenogenetic studies of the homoeotic mutants of Drosophila melanogaster; homoeotic and growth rate genes.", "content": "Phenogenetic studies of the homoeotic mutants of Drosophila melanogaster; homoeotic and growth rate genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991114"}
{"pmid": "20991107", "title": "Psychological and psych iatric concepts in criminology.", "content": "Psychological and psych iatric concepts in criminology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991107"}
{"pmid": "20991108", "title": "The youth village; a plan for the reeducation of the uprooted.", "content": "The youth village; a plan for the reeducation of the uprooted.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991108"}
{"pmid": "20991115", "title": "Monozygotic and dizygotic twin birth frequencies in the total, the white and colored U.S. populations.", "content": "Monozygotic and dizygotic twin birth frequencies in the total, the white and colored U.S. populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991115"}
{"pmid": "20991119", "title": "Diagnosis of extra uterine pregnancy (an analysis of 100 cases).", "content": "Diagnosis of extra uterine pregnancy (an analysis of 100 cases).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991119"}
{"pmid": "20991120", "title": "The help of anterior shoulder during ante-natal examination and abnormal labours.", "content": "The help of anterior shoulder during ante-natal examination and abnormal labours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991120"}
{"pmid": "20991121", "title": "The present status of folic acid.", "content": "The present status of folic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991121"}
{"pmid": "20991122", "title": "Treatment of liver extract sensitivity.", "content": "Treatment of liver extract sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991122"}
{"pmid": "20991123", "title": "Rupture of the spleen in infectious mononucleosis; a clinicopathologic report of 7 cases.", "content": "Rupture of the spleen in infectious mononucleosis; a clinicopathologic report of 7 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991123"}
{"pmid": "20991124", "title": "Infectious mononucleosis complicated by spontaneous rupture of the spleen and central nervous system involvement.", "content": "Infectious mononucleosis complicated by spontaneous rupture of the spleen and central nervous system involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991124"}
{"pmid": "20991125", "title": "Infectious lymphadenosis (mononucleosis) and thrombocytopenic purpura; recovery after splenectomy; report of case.", "content": "Infectious lymphadenosis (mononucleosis) and thrombocytopenic purpura; recovery after splenectomy; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991125"}
{"pmid": "20991126", "title": "Experimental leukocytosis; the inefficacy of p-chloro-xylenol and methyl acetamide as bone marrow stimulants.", "content": "Experimental leukocytosis; the inefficacy of p-chloro-xylenol and methyl acetamide as bone marrow stimulants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991126"}
{"pmid": "20991127", "title": "The excretion of urobilinogen in the stools and urine during malarial infection.", "content": "The excretion of urobilinogen in the stools and urine during malarial infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991127"}
{"pmid": "20991131", "title": "Fibroids complicating pregnancy.", "content": "Fibroids complicating pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991131"}
{"pmid": "20991132", "title": "Dysmenorrhea.", "content": "Dysmenorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991132"}
{"pmid": "20991133", "title": "The recognition of an acutely inflamed eye by the general practicing physician.", "content": "The recognition of an acutely inflamed eye by the general practicing physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991133"}
{"pmid": "20991134", "title": "Peptic ulcers in children.", "content": "Peptic ulcers in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991134"}
{"pmid": "20991135", "title": "Traumatic neuroses.", "content": "Traumatic neuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991135"}
{"pmid": "20991136", "title": "The osteopathic treatment of asthma.", "content": "The osteopathic treatment of asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991136"}
{"pmid": "20991137", "title": "Developmental anomalies.", "content": "Developmental anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991137"}
{"pmid": "20991138", "title": "An index for children's blood counts.", "content": "An index for children's blood counts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991138"}
{"pmid": "20991140", "title": "Neural leprosy.", "content": "Neural leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991140"}
{"pmid": "20991139", "title": "The osteopathic educational program.", "content": "The osteopathic educational program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991139"}
{"pmid": "20991141", "title": "Pityriasis rosea; treatment with sodium cacodylate.", "content": "Pityriasis rosea; treatment with sodium cacodylate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991141"}
{"pmid": "20991165", "title": "Chronic mercury poisoning.", "content": "Chronic mercury poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991165"}
{"pmid": "20991166", "title": "Bronchiolitis resulting from the handling of bagasse.", "content": "Bronchiolitis resulting from the handling of bagasse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991166"}
{"pmid": "20991167", "title": "The aetiology, prevention and treatment of chronic bronchitis.", "content": "The aetiology, prevention and treatment of chronic bronchitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991167"}
{"pmid": "20991168", "title": "The incidence of siderosis in iron turners and grinders.", "content": "The incidence of siderosis in iron turners and grinders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991168"}
{"pmid": "20991169", "title": "Occupational dermatitis.", "content": "Occupational dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991169"}
{"pmid": "20991170", "title": "Manganese pneumonitis.", "content": "Manganese pneumonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991170"}
{"pmid": "20991171", "title": "The disappearance of sulphemoglobin from the blood of TNT workers in relation to the dynamics of red cell destruction.", "content": "The disappearance of sulphemoglobin from the blood of TNT workers in relation to the dynamics of red cell destruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991171"}
{"pmid": "20991172", "title": "Effects of heat on wireless telegraphy operators hearing and recording Morse messages.", "content": "Effects of heat on wireless telegraphy operators hearing and recording Morse messages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991172"}
{"pmid": "20991173", "title": "A method for studying vibrations transmitted to the hands.", "content": "A method for studying vibrations transmitted to the hands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991173"}
{"pmid": "20991174", "title": "Raynaud's phenomenon in grinders of small metal castings; a clinical and experimental study.", "content": "Raynaud's phenomenon in grinders of small metal castings; a clinical and experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991174"}
{"pmid": "20991175", "title": "A report of three cases of accidental poisoning by sodium tellurite.", "content": "A report of three cases of accidental poisoning by sodium tellurite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991175"}
{"pmid": "20991176", "title": "Some toxic effects of vanadium pentoxide.", "content": "Some toxic effects of vanadium pentoxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991176"}
{"pmid": "20991177", "title": "Toxic manifestations of osmium tetroxide.", "content": "Toxic manifestations of osmium tetroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991177"}
{"pmid": "20991178", "title": "An apparatus for the maintenance of a carbon dust cloud of constant concentration.", "content": "An apparatus for the maintenance of a carbon dust cloud of constant concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991178"}
{"pmid": "20991182", "title": "Commercial nursing and boarding homes in Philadelphia.", "content": "Commercial nursing and boarding homes in Philadelphia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991182"}
{"pmid": "20991195", "title": "Miíase Palpebral.", "content": "Miíase Palpebral.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991195"}
{"pmid": "20991213", "title": "Essential oral hyperthermia; report of a study of 25 cases of low grade fever.", "content": "Essential oral hyperthermia; report of a study of 25 cases of low grade fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991213"}
{"pmid": "20991214", "title": "The nephrotic phase; its frequency of occurrence and its differential diagnostic value in determining the nature of the rental lesion in 120 patients who died of renal failure.", "content": "The nephrotic phase; its frequency of occurrence and its differential diagnostic value in determining the nature of the rental lesion in 120 patients who died of renal failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991214"}
{"pmid": "20991215", "title": "Medico-legal problems in distinguishing accident from suicide.", "content": "Medico-legal problems in distinguishing accident from suicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991215"}
{"pmid": "20991216", "title": "Penicillin in the treatment of putrid lung abscess.", "content": "Penicillin in the treatment of putrid lung abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991216"}
{"pmid": "20991217", "title": "Treatment of various infections with penicillin X, with a preliminary note on the value of penicillin X in scarlet fever.", "content": "Treatment of various infections with penicillin X, with a preliminary note on the value of penicillin X in scarlet fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991217"}
{"pmid": "20991218", "title": "Serum amylase and serum lipase in mumps.", "content": "Serum amylase and serum lipase in mumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991218"}
{"pmid": "20991219", "title": "The prothrombinopenic effect of massive salicylate therapy in acute rheumatic fever.", "content": "The prothrombinopenic effect of massive salicylate therapy in acute rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991219"}
{"pmid": "20991220", "title": "Plasmochin toxicity; analysis of 258 cases.", "content": "Plasmochin toxicity; analysis of 258 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991220"}
{"pmid": "20991221", "title": "Infectious mononucleosis; report of an epidemic in an Army post.", "content": "Infectious mononucleosis; report of an epidemic in an Army post.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991221"}
{"pmid": "20991223", "title": "Myxedema, controlled by thyroid extract for 52 years; report of a case.", "content": "Myxedema, controlled by thyroid extract for 52 years; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991223"}
{"pmid": "20991222", "title": "Acquired syphilis of the lung; report of a case with autopsy findings and demonstration of spirochetes.", "content": "Acquired syphilis of the lung; report of a case with autopsy findings and demonstration of spirochetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991222"}
{"pmid": "20991224", "title": "Rupture of an aneurysm of a sinus of Valsalva into the right auricle.", "content": "Rupture of an aneurysm of a sinus of Valsalva into the right auricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991224"}
{"pmid": "20991225", "title": "The influence of ovarian activity and administered estrogens upon diabetes mellitus; case report.", "content": "The influence of ovarian activity and administered estrogens upon diabetes mellitus; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991225"}
{"pmid": "20991226", "title": "MURINE typhus fever.", "content": "MURINE typhus fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991226"}
{"pmid": "20991227", "title": "Amebiasis among the American armed forces in the Middle East.", "content": "Amebiasis among the American armed forces in the Middle East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991227"}
{"pmid": "20991228", "title": "Thromboangiitis of pulmonary vessels associated with aneurysm of pulmonary artery.", "content": "Thromboangiitis of pulmonary vessels associated with aneurysm of pulmonary artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991228"}
{"pmid": "20991229", "title": "Acute porphyria; investigations on the pathology of the porphyrins and identification of the excretion of uroporphyrin I.", "content": "Acute porphyria; investigations on the pathology of the porphyrins and identification of the excretion of uroporphyrin I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991229"}
{"pmid": "20991230", "title": "Peripheral blood flow, rectal and skin temperature in congestive heart failure; the effects of rapid digitalization in this state.", "content": "Peripheral blood flow, rectal and skin temperature in congestive heart failure; the effects of rapid digitalization in this state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991230"}
{"pmid": "20991231", "title": "Patent ductus arteriosus with subacute bacterial endarteritis; diagnosis and indications for operation.", "content": "Patent ductus arteriosus with subacute bacterial endarteritis; diagnosis and indications for operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991231"}
{"pmid": "20991232", "title": "Pneumonia in the aged; an analysis of one hundred sixty-six cases of its occurrence in patients sixty years old and over.", "content": "Pneumonia in the aged; an analysis of one hundred sixty-six cases of its occurrence in patients sixty years old and over.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991232"}
{"pmid": "20991233", "title": "Allergy; a review of the literature of 1944 and 1945, with comments on future problems.", "content": "Allergy; a review of the literature of 1944 and 1945, with comments on future problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991233"}
{"pmid": "20991236", "title": "Progress of aviation medicine in the Royal Air Force and its application to the problems of civil aviation.", "content": "Progress of aviation medicine in the Royal Air Force and its application to the problems of civil aviation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991236"}
{"pmid": "20991237", "title": "Inadequate feeding in hospitals; a study of contributory factors.", "content": "Inadequate feeding in hospitals; a study of contributory factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991237"}
{"pmid": "20991238", "title": "The itchy patient.", "content": "The itchy patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991238"}
{"pmid": "20991239", "title": "Tropical ulcers and penicillin.", "content": "Tropical ulcers and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991239"}
{"pmid": "20991240", "title": "Angioblastoma of the breast complicating pregnancy.", "content": "Angioblastoma of the breast complicating pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991240"}
{"pmid": "20991241", "title": "SAMPLE surveys.", "content": "SAMPLE surveys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991241"}
{"pmid": "20991242", "title": "Psychiatric cases referred by after-care officers in Region 7.", "content": "Psychiatric cases referred by after-care officers in Region 7.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991242"}
{"pmid": "20991243", "title": "Gas gangrene of the gall-bladder.", "content": "Gas gangrene of the gall-bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991243"}
{"pmid": "20991244", "title": "Black tongue and oral penicillin.", "content": "Black tongue and oral penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991244"}
{"pmid": "20991245", "title": "Hay fever and asthma in general practice.", "content": "Hay fever and asthma in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991245"}
{"pmid": "20991246", "title": "Vocational dermatoses.", "content": "Vocational dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991246"}
{"pmid": "20991247", "title": "ILLINOIS Revised Mental Health Act.", "content": "ILLINOIS Revised Mental Health Act.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991247"}
{"pmid": "20991248", "title": "Experimental studies of starvation on men.", "content": "Experimental studies of starvation on men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991248"}
{"pmid": "20991249", "title": "The clinical treatment of anterior poliomyelitis.", "content": "The clinical treatment of anterior poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991249"}
{"pmid": "20991250", "title": "The 1945 polio epidemic in Rockford, Illinois.", "content": "The 1945 polio epidemic in Rockford, Illinois.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991250"}
{"pmid": "20991251", "title": "Administrative problems of the poliomyelitis epidemic in the Rockford, Illinois area July 1st to December 1st, 1945.", "content": "Administrative problems of the poliomyelitis epidemic in the Rockford, Illinois area July 1st to December 1st, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991251"}
{"pmid": "20991252", "title": "Statistical aspects of the 1945 poliomyelitis epidemic Rockford, Illinois.", "content": "Statistical aspects of the 1945 poliomyelitis epidemic Rockford, Illinois.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991252"}
{"pmid": "20991253", "title": "Pneumococcic meningitis.", "content": "Pneumococcic meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991253"}
{"pmid": "20991254", "title": "The relationship of hormones to the peptic ulcer problem.", "content": "The relationship of hormones to the peptic ulcer problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991254"}
{"pmid": "20991255", "title": "Thiouracil.", "content": "Thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991255"}
{"pmid": "20991256", "title": "Sympathetic blocks.", "content": "Sympathetic blocks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991256"}
{"pmid": "20991280", "title": "The management of compound fractures of the skull based on experience with 175 cases.", "content": "The management of compound fractures of the skull based on experience with 175 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991280"}
{"pmid": "20991281", "title": "Actinomycosis, with special reference to its pathogenesis, its treatment and its cure with penicillin.", "content": "Actinomycosis, with special reference to its pathogenesis, its treatment and its cure with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991281"}
{"pmid": "20991282", "title": "HISTAMINE and allergy.", "content": "HISTAMINE and allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991282"}
{"pmid": "20991283", "title": "Some aspects of the metabolism and excretion of androgens, 17-ketosteroids, and oestrogens.", "content": "Some aspects of the metabolism and excretion of androgens, 17-ketosteroids, and oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991283"}
{"pmid": "20991284", "title": "Several abnormalities can be detected on analysis of the electrocardiogram.", "content": "Several abnormalities can be detected on analysis of the electrocardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991284"}
{"pmid": "20991285", "title": "[Appendicitis complications].", "content": "[Appendicitis complications].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991285"}
{"pmid": "20991286", "title": "[Abscess formation, involving the wall of the cervical oesophagus, and extending into the right superior mediastinum].", "content": "[Abscess formation, involving the wall of the cervical oesophagus, and extending into the right superior mediastinum].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991286"}
{"pmid": "20991287", "title": "History and development of physical medicine.", "content": "History and development of physical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991287"}
{"pmid": "20991288", "title": "Some factors to be considered in prescribing physical medicine.", "content": "Some factors to be considered in prescribing physical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991288"}
{"pmid": "20991289", "title": "Physical therapy in medical conditions.", "content": "Physical therapy in medical conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991289"}
{"pmid": "20991290", "title": "The use of physical agents in dermatology.", "content": "The use of physical agents in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991290"}
{"pmid": "20991291", "title": "The principles of the physical treatment of minor injuries.", "content": "The principles of the physical treatment of minor injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991291"}
{"pmid": "20991292", "title": "Physical medicine in the treatment of fractures.", "content": "Physical medicine in the treatment of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991292"}
{"pmid": "20991293", "title": "Physical therapy in some common orthopedic disabilities.", "content": "Physical therapy in some common orthopedic disabilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991293"}
{"pmid": "20991294", "title": "Physical medicine and neurology.", "content": "Physical medicine and neurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991294"}
{"pmid": "20991295", "title": "Physical medicine in acute and convalescent poliomyelitis.", "content": "Physical medicine in acute and convalescent poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991295"}
{"pmid": "20991296", "title": "Physical therapy and occupational therapy in psychiatry.", "content": "Physical therapy and occupational therapy in psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991296"}
{"pmid": "20991297", "title": "Rehabilitation and employment.", "content": "Rehabilitation and employment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991297"}
{"pmid": "20991298", "title": "Aspects of physical therapy and reconditioning in some of the Army hospitals.", "content": "Aspects of physical therapy and reconditioning in some of the Army hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991298"}
{"pmid": "20991299", "title": "Fever; chemotherapy.", "content": "Fever; chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991299"}
{"pmid": "20991300", "title": "Uses of cold in medicine and surgery.", "content": "Uses of cold in medicine and surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991300"}
{"pmid": "20991309", "title": "Emotional vacuum and alcoholism.", "content": "Emotional vacuum and alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991309"}
{"pmid": "20991306", "title": "Comments on the report of the Committee on Psychiatric Standards and Policies of the American Psychiatric Association.", "content": "Comments on the report of the Committee on Psychiatric Standards and Policies of the American Psychiatric Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991306"}
{"pmid": "20991307", "title": "The nervous veteran.", "content": "The nervous veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991307"}
{"pmid": "20991308", "title": "Problems of psychiatric diagnosis.", "content": "Problems of psychiatric diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991308"}
{"pmid": "20991310", "title": "Prolonged electroconvulsive therapy.", "content": "Prolonged electroconvulsive therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991310"}
{"pmid": "20991311", "title": "Verbal polarity in dementia precox.", "content": "Verbal polarity in dementia precox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991311"}
{"pmid": "20991312", "title": "Foreseeing and forestalling tuberculosis; introduction to symposium.", "content": "Foreseeing and forestalling tuberculosis; introduction to symposium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991312"}
{"pmid": "20991314", "title": "Thoracoscopy as a method of exploration in penetrating injuries of the thorax.", "content": "Thoracoscopy as a method of exploration in penetrating injuries of the thorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991314"}
{"pmid": "20991313", "title": "Foreseeing and forestalling tuberculosis; a scheme in operation 29 years.", "content": "Foreseeing and forestalling tuberculosis; a scheme in operation 29 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991313"}
{"pmid": "20991315", "title": "Tuberculosis among sanatorium personnel.", "content": "Tuberculosis among sanatorium personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991315"}
{"pmid": "20991317", "title": "Experiences with B. C. G. in Latin America.", "content": "Experiences with B. C. G. in Latin America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991317"}
{"pmid": "20991316", "title": "The epidemiology of tuberculosis in Brazil and vaccination with B. C. G.", "content": "The epidemiology of tuberculosis in Brazil and vaccination with B. C. G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991316"}
{"pmid": "20991318", "title": "Notes on the use of spray killing against mosquitoes.", "content": "Notes on the use of spray killing against mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991318"}
{"pmid": "20991320", "title": "The cataract operation.", "content": "The cataract operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991320"}
{"pmid": "20991321", "title": "The breeding of mosquitoes in the weepholes of stone pitched drains.", "content": "The breeding of mosquitoes in the weepholes of stone pitched drains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991321"}
{"pmid": "20991319", "title": "Duration of penicillin in the blood after single injections.", "content": "Duration of penicillin in the blood after single injections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991319"}
{"pmid": "20991324", "title": "The progress of dermatology.", "content": "The progress of dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991324"}
{"pmid": "20991323", "title": "The treatment of fractured clavicles by plaster of paris bandages.", "content": "The treatment of fractured clavicles by plaster of paris bandages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991323"}
{"pmid": "20991322", "title": "Psychiatric opinion and crime with special reference to temporary insanity.", "content": "Psychiatric opinion and crime with special reference to temporary insanity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991322"}
{"pmid": "20991328", "title": "Recent legislation affecting medical licensure.", "content": "Recent legislation affecting medical licensure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991328"}
{"pmid": "20991329", "title": "EXAMINING boards in the medical specialties.", "content": "EXAMINING boards in the medical specialties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991329"}
{"pmid": "20991326", "title": "Meningococcaemia; bacteriology, serology and aetiology.", "content": "Meningococcaemia; bacteriology, serology and aetiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991326"}
{"pmid": "20991331", "title": "Stockholm, 1946.", "content": "Stockholm, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991331"}
{"pmid": "20991325", "title": "Anticoagulant therapy in thrombosis.", "content": "Anticoagulant therapy in thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991325"}
{"pmid": "20991330", "title": "Patent medicines.", "content": "Patent medicines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991330"}
{"pmid": "20991327", "title": "The treatment of cholera by intravenous saline injections; with particular reference to the contributions of Dr. Thomas Aitchison Latta of Leith.", "content": "The treatment of cholera by intravenous saline injections; with particular reference to the contributions of Dr. Thomas Aitchison Latta of Leith.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991327"}
{"pmid": "20991332", "title": "A study of gastric acidity in disease.", "content": "A study of gastric acidity in disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991332"}
{"pmid": "20991333", "title": "Menstruation and its irregularities; a statistical study.", "content": "Menstruation and its irregularities; a statistical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991333"}
{"pmid": "20991334", "title": "Science and the student.", "content": "Science and the student.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991334"}
{"pmid": "20991336", "title": "MALARIA.", "content": "MALARIA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991336"}
{"pmid": "20991335", "title": "Benign eosinophilia with pulmonary shadows.", "content": "Benign eosinophilia with pulmonary shadows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991335"}
{"pmid": "20991338", "title": "Disorders of the gall bladder; observations on the unusual etiological factors.", "content": "Disorders of the gall bladder; observations on the unusual etiological factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991338"}
{"pmid": "20991337", "title": "Pneumococcal meningitis; a report of two cases which recovered with residual neuropsychiatric symptoms following treatment with penicillin.", "content": "Pneumococcal meningitis; a report of two cases which recovered with residual neuropsychiatric symptoms following treatment with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991337"}
{"pmid": "20991343", "title": "Meningitis; an analysis of 255 cases.", "content": "Meningitis; an analysis of 255 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991343"}
{"pmid": "20991339", "title": "Acute paranitraniline poisoning.", "content": "Acute paranitraniline poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991339"}
{"pmid": "20991341", "title": "What's in a name [nomenclature of drugs].", "content": "What's in a name [nomenclature of drugs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991341"}
{"pmid": "20991340", "title": "Facts, fads and fancy in intravenous medication.", "content": "Facts, fads and fancy in intravenous medication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991340"}
{"pmid": "20991342", "title": "P-P interval and retrograde (V-A) conduction in complete heart block.", "content": "P-P interval and retrograde (V-A) conduction in complete heart block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991342"}
{"pmid": "20991344", "title": "Amoebiasis in children; a brief note on its incidence, with a report of a case of amoebic dysentery in a child four and a half months old.", "content": "Amoebiasis in children; a brief note on its incidence, with a report of a case of amoebic dysentery in a child four and a half months old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991344"}
{"pmid": "20991345", "title": "Thiouracil and thiourea in the treatment of thyrotoxicosis.", "content": "Thiouracil and thiourea in the treatment of thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991345"}
{"pmid": "20991346", "title": "Nikethamide.", "content": "Nikethamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991346"}
{"pmid": "20991348", "title": "The deficiency factor in the aetiology of portal cirrhosis in the Punjab; a preliminary report.", "content": "The deficiency factor in the aetiology of portal cirrhosis in the Punjab; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991348"}
{"pmid": "20991347", "title": "Total laryngectomy; a simple device for voice production.", "content": "Total laryngectomy; a simple device for voice production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991347"}
{"pmid": "20991349", "title": "Primary peritonitis in children.", "content": "Primary peritonitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991349"}
{"pmid": "20991352", "title": "Malaria in disguise.", "content": "Malaria in disguise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991352"}
{"pmid": "20991350", "title": "A note on lobectomy.", "content": "A note on lobectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991350"}
{"pmid": "20991351", "title": "The common cold and bad throat and their sequelae; some important considerations in treatment.", "content": "The common cold and bad throat and their sequelae; some important considerations in treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991351"}
{"pmid": "20991353", "title": "Incidence of amoebic carriers in Bombay.", "content": "Incidence of amoebic carriers in Bombay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991353"}
{"pmid": "20991354", "title": "Incidence of chronic amoebiasis in Bombay and non-dysenteric amoebic abdominal syndromes.", "content": "Incidence of chronic amoebiasis in Bombay and non-dysenteric amoebic abdominal syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991354"}
{"pmid": "20991355", "title": "Calcareous pancreatitis; autopsy report of one case.", "content": "Calcareous pancreatitis; autopsy report of one case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991355"}
{"pmid": "20991356", "title": "Uraemia; an analysis of 98 cases admitted to the K. E. M. Hospital from 1st January 34 to 30th June 44 with post-mortem findings of 36 cases.", "content": "Uraemia; an analysis of 98 cases admitted to the K. E. M. Hospital from 1st January 34 to 30th June 44 with post-mortem findings of 36 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991356"}
{"pmid": "20991357", "title": "Primary amoebic abscess of the lung; a case report.", "content": "Primary amoebic abscess of the lung; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991357"}
{"pmid": "20991358", "title": "Spinal tumours.", "content": "Spinal tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991358"}
{"pmid": "20991360", "title": "Endocrinology in the aged.", "content": "Endocrinology in the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991360"}
{"pmid": "20991359", "title": "Blood transfusion malaria in the post war period.", "content": "Blood transfusion malaria in the post war period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991359"}
{"pmid": "20991361", "title": "Vitamin D.", "content": "Vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991361"}
{"pmid": "20991363", "title": "Varicose veins.", "content": "Varicose veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991363"}
{"pmid": "20991362", "title": "The endocrine basis of spontaneous abortion.", "content": "The endocrine basis of spontaneous abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991362"}
{"pmid": "20991364", "title": "New concepts of medical education.", "content": "New concepts of medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991364"}
{"pmid": "20991365", "title": "The diuretic effect of globin in chronic glomerulonephritis.", "content": "The diuretic effect of globin in chronic glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991365"}
{"pmid": "20991366", "title": "Gram-negative bacillus empyema cured by intrapleural penicillin.", "content": "Gram-negative bacillus empyema cured by intrapleural penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991366"}
{"pmid": "20991367", "title": "Chronic nasal obstruction; its causes and treatment.", "content": "Chronic nasal obstruction; its causes and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991367"}
{"pmid": "20991368", "title": "Survival of hypothermia by men immersed in the ocean.", "content": "Survival of hypothermia by men immersed in the ocean.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991368"}
{"pmid": "20991369", "title": "The use of penicillin in acute sore throat.", "content": "The use of penicillin in acute sore throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991369"}
{"pmid": "20991370", "title": "DIPHTHERIA mortality in large cities in the United States in 1945.", "content": "DIPHTHERIA mortality in large cities in the United States in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991370"}
{"pmid": "20991371", "title": "Diaphragmatic flutter, with symptoms suggesting angina pectoris.", "content": "Diaphragmatic flutter, with symptoms suggesting angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991371"}
{"pmid": "20991372", "title": "Final report of the Committee on the Teaching of Tropical Medicine of the Association of American Medical Colleges.", "content": "Final report of the Committee on the Teaching of Tropical Medicine of the Association of American Medical Colleges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991372"}
{"pmid": "20991373", "title": "The program of premedical training at Vanderbilt University.", "content": "The program of premedical training at Vanderbilt University.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991373"}
{"pmid": "20991374", "title": "Graduate training in ophthalmology.", "content": "Graduate training in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991374"}
{"pmid": "20991375", "title": "The place of neurology in the medical firmament.", "content": "The place of neurology in the medical firmament.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991375"}
{"pmid": "20991376", "title": "The future of medical education.", "content": "The future of medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991376"}
{"pmid": "20991377", "title": "The early diagnosis of neurosurgical lesions.", "content": "The early diagnosis of neurosurgical lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991377"}
{"pmid": "20991378", "title": "Correction of some of nature's mistakes by operative intervention.", "content": "Correction of some of nature's mistakes by operative intervention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991378"}
{"pmid": "20991379", "title": "Two cases of human cloaca.", "content": "Two cases of human cloaca.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991379"}
{"pmid": "20991380", "title": "Benign papilloma of the ureter.", "content": "Benign papilloma of the ureter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991380"}
{"pmid": "20991381", "title": "The treatment of syphilis with penicillin.", "content": "The treatment of syphilis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991381"}
{"pmid": "20991382", "title": "Diabetes in pregnancy.", "content": "Diabetes in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991382"}
{"pmid": "20991383", "title": "Electric shock therapy in an Army general hospital.", "content": "Electric shock therapy in an Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991383"}
{"pmid": "20991384", "title": "The role of the physician in adoption.", "content": "The role of the physician in adoption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991384"}
{"pmid": "20991385", "title": "Theophyllin in the treatment of migraine.", "content": "Theophyllin in the treatment of migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991385"}
{"pmid": "20991386", "title": "Body fluid balance, with particular reference to heart failure.", "content": "Body fluid balance, with particular reference to heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991386"}
{"pmid": "20991387", "title": "PENICILLIN in syphilis and gonorrhea.", "content": "PENICILLIN in syphilis and gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991387"}
{"pmid": "20991426", "title": "A proctologist's message to the general practitioner.", "content": "A proctologist's message to the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991426"}
{"pmid": "20991427", "title": "The nutritional status of the people of South Carolina.", "content": "The nutritional status of the people of South Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991427"}
{"pmid": "20991428", "title": "Congenital malformations following rubella in the mother.", "content": "Congenital malformations following rubella in the mother.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991428"}
{"pmid": "20991429", "title": "The future of medicine.", "content": "The future of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991429"}
{"pmid": "20991430", "title": "Surgical treatment of cancer of the colon.", "content": "Surgical treatment of cancer of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991430"}
{"pmid": "20991421", "title": "The electroencephalogram in subarachnoid hemorrhage.", "content": "The electroencephalogram in subarachnoid hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991421"}
{"pmid": "20991422", "title": "The lateral decubitus position in x-ray examination of the chest.", "content": "The lateral decubitus position in x-ray examination of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991422"}
{"pmid": "20991431", "title": "Some recent advances in pediatrics.", "content": "Some recent advances in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991431"}
{"pmid": "20991432", "title": "Preoperative and postoperative care of laparotomy patients.", "content": "Preoperative and postoperative care of laparotomy patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991432"}
{"pmid": "20991420", "title": "Myocardial insufficiency.", "content": "Myocardial insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991420"}
{"pmid": "20991423", "title": "Combined ileo-vesical and sigmoido-vesical fistula secondary to diverticulitis; case report.", "content": "Combined ileo-vesical and sigmoido-vesical fistula secondary to diverticulitis; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991423"}
{"pmid": "20991425", "title": "Massive pulmonary embolism; based in part on a study of eighty-eight fatal cases.", "content": "Massive pulmonary embolism; based in part on a study of eighty-eight fatal cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991425"}
{"pmid": "20991435", "title": "Population.", "content": "Population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991435"}
{"pmid": "20991436", "title": "Gonorrhoea in the female; diagnosis and treatment.", "content": "Gonorrhoea in the female; diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991436"}
{"pmid": "20991424", "title": "Essays on the biology of disease.", "content": "Essays on the biology of disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991424"}
{"pmid": "20991437", "title": "Treatment of lupus vulgaris with calciferol.", "content": "Treatment of lupus vulgaris with calciferol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991437"}
{"pmid": "20991438", "title": "Oral administration of penicillin to infants.", "content": "Oral administration of penicillin to infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991438"}
{"pmid": "20991439", "title": "Homelessness in children; causes and prevention; analysis of unparented children in three English counties.", "content": "Homelessness in children; causes and prevention; analysis of unparented children in three English counties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991439"}
{"pmid": "20991440", "title": "WORLD'S food.", "content": "WORLD'S food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991440"}
{"pmid": "20991441", "title": "Democratic nursing.", "content": "Democratic nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991441"}
{"pmid": "20991442", "title": "Accidental laboratory infection with tsutsugamushi rickettsia.", "content": "Accidental laboratory infection with tsutsugamushi rickettsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991442"}
{"pmid": "20991443", "title": "The control of poliomyelitis.", "content": "The control of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991443"}
{"pmid": "20991444", "title": "Pin and graft arthrodesis for osteo-arthritis of the hip.", "content": "Pin and graft arthrodesis for osteo-arthritis of the hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991444"}
{"pmid": "20991445", "title": "Survival of penicillin-sensitive organisms in dried penicillin.", "content": "Survival of penicillin-sensitive organisms in dried penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991445"}
{"pmid": "20991446", "title": "BICENTENARY of the London Lock Hospital.", "content": "BICENTENARY of the London Lock Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991446"}
{"pmid": "20991447", "title": "Medicine and industrial safety.", "content": "Medicine and industrial safety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991447"}
{"pmid": "20991448", "title": "Prophylactic penicillin in surgery.", "content": "Prophylactic penicillin in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991448"}
{"pmid": "20991449", "title": "The tuberculosis service and the future.", "content": "The tuberculosis service and the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991449"}
{"pmid": "20991450", "title": "Variations in reproductive pattern according to social class.", "content": "Variations in reproductive pattern according to social class.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991450"}
{"pmid": "20991451", "title": "Demodex folliculorum in the human nipple.", "content": "Demodex folliculorum in the human nipple.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991451"}
{"pmid": "20991452", "title": "Gramicidin S.", "content": "Gramicidin S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991452"}
{"pmid": "20991453", "title": "Ovarian cystectomy of twisted cysts.", "content": "Ovarian cystectomy of twisted cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991453"}
{"pmid": "20991454", "title": "Hernia through the foramen of Winslow.", "content": "Hernia through the foramen of Winslow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991454"}
{"pmid": "20991455", "title": "Nutrition.", "content": "Nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991455"}
{"pmid": "20991456", "title": "Tropical diseases.", "content": "Tropical diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991456"}
{"pmid": "20991457", "title": "ALLEGE cruelty to cats.", "content": "ALLEGE cruelty to cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991457"}
{"pmid": "20991458", "title": "Recent advances in orthopedic surgery.", "content": "Recent advances in orthopedic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991458"}
{"pmid": "20991459", "title": "The absorption, distribution and excretion of penicillin.", "content": "The absorption, distribution and excretion of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991459"}
{"pmid": "20991460", "title": "Inappropriate treatment of moles predisposing to melanotic malignancies.", "content": "Inappropriate treatment of moles predisposing to melanotic malignancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991460"}
{"pmid": "20991461", "title": "The psychosomatic history.", "content": "The psychosomatic history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991461"}
{"pmid": "20991462", "title": "Can we control venereal disease?", "content": "Can we control venereal disease?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991462"}
{"pmid": "20991463", "title": "Why we oppose compulsory health insurance.", "content": "Why we oppose compulsory health insurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991463"}
{"pmid": "20991469", "title": "SUMMARY of the Report of the Health Survey and Development Committee.", "content": "SUMMARY of the Report of the Health Survey and Development Committee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991469"}
{"pmid": "20991478", "title": "Some notes on the treatment of pulmonary tuberculosis.", "content": "Some notes on the treatment of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991478"}
{"pmid": "20991479", "title": "Recent experiences in Canada and the United States.", "content": "Recent experiences in Canada and the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991479"}
{"pmid": "20991480", "title": "Psychotic casualties in New Guinea, with special reference to the use of convulsive therapy in forward areas.", "content": "Psychotic casualties in New Guinea, with special reference to the use of convulsive therapy in forward areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991480"}
{"pmid": "20991481", "title": "Congenital fibrocystic disease of the pancreas.", "content": "Congenital fibrocystic disease of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991481"}
{"pmid": "20991482", "title": "Backache in soldiers.", "content": "Backache in soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991482"}
{"pmid": "20991483", "title": "Blood loss in caesarean section.", "content": "Blood loss in caesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991483"}
{"pmid": "20991484", "title": "Chronic vesiculitis as a factor in the production of non-gonococcal urethral discharges.", "content": "Chronic vesiculitis as a factor in the production of non-gonococcal urethral discharges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991484"}
{"pmid": "20991485", "title": "WOMEN in medicine.", "content": "WOMEN in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991485"}
{"pmid": "20991486", "title": "Amyotonia congenita (Oppenheim's disease).", "content": "Amyotonia congenita (Oppenheim's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991486"}
{"pmid": "20991487", "title": "Congenital dislocation of the hip.", "content": "Congenital dislocation of the hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991487"}
{"pmid": "20991488", "title": "The Rh blood types and their reactions.", "content": "The Rh blood types and their reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991488"}
{"pmid": "20991489", "title": "Early diagnosis in tumours of the central nervous system.", "content": "Early diagnosis in tumours of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991489"}
{"pmid": "20991490", "title": "Studies in nicotinic acid.", "content": "Studies in nicotinic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991490"}
{"pmid": "20991491", "title": "Acceptable words; quotations with a medical bearing.", "content": "Acceptable words; quotations with a medical bearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991491"}
{"pmid": "20991492", "title": "A method for the removal of tonsils and adenoids under local anaesthesia with the patient in the recumbent position.", "content": "A method for the removal of tonsils and adenoids under local anaesthesia with the patient in the recumbent position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991492"}
{"pmid": "20991493", "title": "Gargoylism.", "content": "Gargoylism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991493"}
{"pmid": "20991495", "title": "Research at the Kanematsu Institute.", "content": "Research at the Kanematsu Institute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991495"}
{"pmid": "20991494", "title": "Spinal anaesthesia and chloroform; a comparison of mortality.", "content": "Spinal anaesthesia and chloroform; a comparison of mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991494"}
{"pmid": "20991496", "title": "Studies on Rh iso-immunization.", "content": "Studies on Rh iso-immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991496"}
{"pmid": "20991497", "title": "The results of penicillin therapy in the treatment of gonorrhoea.", "content": "The results of penicillin therapy in the treatment of gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991497"}
{"pmid": "20991498", "title": "The rehabilitation of war neurotics.", "content": "The rehabilitation of war neurotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991498"}
{"pmid": "20991499", "title": "The rehabilitation of war neurotics.", "content": "The rehabilitation of war neurotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991499"}
{"pmid": "20991500", "title": "The detection of the cysts of Entamoeba histolytica in the faeces by microscopic examination.", "content": "The detection of the cysts of Entamoeba histolytica in the faeces by microscopic examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991500"}
{"pmid": "20991501", "title": "The rehabilitation of war neurotics.", "content": "The rehabilitation of war neurotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991501"}
{"pmid": "20991502", "title": "Basal arachnoiditis.", "content": "Basal arachnoiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991502"}
{"pmid": "20991503", "title": "Blood loss in caesarean section.", "content": "Blood loss in caesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991503"}
{"pmid": "20991504", "title": "The responsibility of the doctor in regard to rehabilitation in private and hospital practice.", "content": "The responsibility of the doctor in regard to rehabilitation in private and hospital practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991504"}
{"pmid": "20991505", "title": "A rare iso-haemagglutinogen.", "content": "A rare iso-haemagglutinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991505"}
{"pmid": "20991506", "title": "National health.", "content": "National health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991506"}
{"pmid": "20991507", "title": "Curare in anaesthesia; a preliminary note.", "content": "Curare in anaesthesia; a preliminary note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991507"}
{"pmid": "20991508", "title": "Congenital cardiac defects associated with maternal rubella.", "content": "Congenital cardiac defects associated with maternal rubella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991508"}
{"pmid": "20991509", "title": "Agglutination titres with Bacillus proteus (OXK) in human sera.", "content": "Agglutination titres with Bacillus proteus (OXK) in human sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991509"}
{"pmid": "20991510", "title": "Tsutsugamushi fever in natives.", "content": "Tsutsugamushi fever in natives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991510"}
{"pmid": "20991511", "title": "Colloid degeneration of the skin; report of eight cases.", "content": "Colloid degeneration of the skin; report of eight cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991511"}
{"pmid": "20991512", "title": "Intrauterine foetal death due to strangulation of the cord.", "content": "Intrauterine foetal death due to strangulation of the cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991512"}
{"pmid": "20991513", "title": "Patent ductus arteriosus.", "content": "Patent ductus arteriosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991513"}
{"pmid": "20991514", "title": "Ollier's disease.", "content": "Ollier's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991514"}
{"pmid": "20991515", "title": "Demyelinating diseases of man and animals.", "content": "Demyelinating diseases of man and animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991515"}
{"pmid": "20991516", "title": "Leprosy, a post-war problem.", "content": "Leprosy, a post-war problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991516"}
{"pmid": "20991517", "title": "Oxidase and diabetes.", "content": "Oxidase and diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991517"}
{"pmid": "20991518", "title": "Report of cases of ten-year survivals of cancer from the hospitals of Rochester.", "content": "Report of cases of ten-year survivals of cancer from the hospitals of Rochester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991518"}
{"pmid": "20991528", "title": "The surgery of the innominate artery.", "content": "The surgery of the innominate artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991528"}
{"pmid": "20991529", "title": "An outline for the treatment of severe burns.", "content": "An outline for the treatment of severe burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991529"}
{"pmid": "20991530", "title": "Effervescent mixtures as adjuvants to the rapid absorption of ingested drugs.", "content": "Effervescent mixtures as adjuvants to the rapid absorption of ingested drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991530"}
{"pmid": "20991531", "title": "Neurology.", "content": "Neurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991531"}
{"pmid": "20991532", "title": "Infectious hepatitis.", "content": "Infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991532"}
{"pmid": "20991533", "title": "Pinealoma.", "content": "Pinealoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991533"}
{"pmid": "20991534", "title": "The treatment of some common dermatoses of infancy and childhood.", "content": "The treatment of some common dermatoses of infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991534"}
{"pmid": "20991536", "title": "Congenital cystic disease of the lung.", "content": "Congenital cystic disease of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991536"}
{"pmid": "20991535", "title": "Lanatoside C (cedilanid).", "content": "Lanatoside C (cedilanid).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991535"}
{"pmid": "20991537", "title": "The bone marrow in diseases of the leukopoietic system.", "content": "The bone marrow in diseases of the leukopoietic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991537"}
{"pmid": "20991538", "title": "Calcium metabolism and the parathyroid glands.", "content": "Calcium metabolism and the parathyroid glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991538"}
{"pmid": "20991539", "title": "The experimental approach to a better medical service.", "content": "The experimental approach to a better medical service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991539"}
{"pmid": "20991540", "title": "Moral and psychologic aspects of the control of venereal disease.", "content": "Moral and psychologic aspects of the control of venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991540"}
{"pmid": "20991541", "title": "The hemorrhoidal-prostatic-impotence syndrome.", "content": "The hemorrhoidal-prostatic-impotence syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991541"}
{"pmid": "20991542", "title": "Electrocardiographic evidence of myocardial degeneration in an American prisoner of war following undue physical stress and other factors.", "content": "Electrocardiographic evidence of myocardial degeneration in an American prisoner of war following undue physical stress and other factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991542"}
{"pmid": "20991544", "title": "The physician in the patient-physician relationship.", "content": "The physician in the patient-physician relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991544"}
{"pmid": "20991543", "title": "Medical services and the Veterans Administration.", "content": "Medical services and the Veterans Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991543"}
{"pmid": "20991545", "title": "Evaluation of anthallan treatment of neurodermatitis disseminata and urticaria.", "content": "Evaluation of anthallan treatment of neurodermatitis disseminata and urticaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991545"}
{"pmid": "20991546", "title": "A dressing for burns and extensive abrasions.", "content": "A dressing for burns and extensive abrasions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991546"}
{"pmid": "20991547", "title": "Latent bronchial carcinoma with widespread metastases.", "content": "Latent bronchial carcinoma with widespread metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991547"}
{"pmid": "20991548", "title": "Postradiation pulmonary fibrosis.", "content": "Postradiation pulmonary fibrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991548"}
{"pmid": "20991549", "title": "Some founders of British neurology.", "content": "Some founders of British neurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991549"}
{"pmid": "20991550", "title": "A review of psychiatric casualties among New Zealand troops in Italy.", "content": "A review of psychiatric casualties among New Zealand troops in Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991550"}
{"pmid": "20991551", "title": "Mild hypothyroidism in Christchurch.", "content": "Mild hypothyroidism in Christchurch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991551"}
{"pmid": "20991553", "title": "INFAMOUS conduct in a professional respect.", "content": "INFAMOUS conduct in a professional respect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991553"}
{"pmid": "20991552", "title": "Carbon tetrachloride poisoning; a fatal case following accidental ingestion of carbon tetrachloride.", "content": "Carbon tetrachloride poisoning; a fatal case following accidental ingestion of carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991552"}
{"pmid": "20991554", "title": "The place of the hospital in medical affairs.", "content": "The place of the hospital in medical affairs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991554"}
{"pmid": "20991555", "title": "Soil, food and life.", "content": "Soil, food and life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991555"}
{"pmid": "20991557", "title": "The medical treatment of thyrotoxicosis.", "content": "The medical treatment of thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991557"}
{"pmid": "20991556", "title": "Presidential address.", "content": "Presidential address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991556"}
{"pmid": "20991558", "title": "Thyrotoxicosis.", "content": "Thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991558"}
{"pmid": "20991559", "title": "Vertigo.", "content": "Vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991559"}
{"pmid": "20991560", "title": "Radiotherapy in ophthalmology.", "content": "Radiotherapy in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991560"}
{"pmid": "20991561", "title": "X-ray treatment in ophthalmology.", "content": "X-ray treatment in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991561"}
{"pmid": "20991562", "title": "The use of penicillin in ophthalmology.", "content": "The use of penicillin in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991562"}
{"pmid": "20991563", "title": "Plastic contact lenses.", "content": "Plastic contact lenses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991563"}
{"pmid": "20991564", "title": "Paralysis of deglutition in diphtheria.", "content": "Paralysis of deglutition in diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991564"}
{"pmid": "20991565", "title": "Penicillin administration by indwelling intramuscular needle.", "content": "Penicillin administration by indwelling intramuscular needle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991565"}
{"pmid": "20991566", "title": "Save the foreskins.", "content": "Save the foreskins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991566"}
{"pmid": "20991574", "title": "[Methods of medical teachers].", "content": "[Methods of medical teachers].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991574"}
{"pmid": "20991576", "title": "The art of the surgeon in diagnosis and treatment.", "content": "The art of the surgeon in diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991576"}
{"pmid": "20991577", "title": "A case of acute intestinal amoebiasis.", "content": "A case of acute intestinal amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991577"}
{"pmid": "20991578", "title": "Medicine in the postwar world.", "content": "Medicine in the postwar world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991578"}
{"pmid": "20991579", "title": "Future implications of the Army's wartime experience with tropical diseases.", "content": "Future implications of the Army's wartime experience with tropical diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991579"}
{"pmid": "20991580", "title": "Poliomyelitis in North Carolina.", "content": "Poliomyelitis in North Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991580"}
{"pmid": "20991582", "title": "Symptomatic relief of the allergic reaction with the anti-histamine drug benadryl.", "content": "Symptomatic relief of the allergic reaction with the anti-histamine drug benadryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991582"}
{"pmid": "20991581", "title": "The role of hyperimmune human serum in the prevention and treatment of pertussis.", "content": "The role of hyperimmune human serum in the prevention and treatment of pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991581"}
{"pmid": "20991583", "title": "Bilateral cortical necrosis of the kidneys; bronchopneumonia.", "content": "Bilateral cortical necrosis of the kidneys; bronchopneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991583"}
{"pmid": "20991584", "title": "A ten-year survey of ectopic pregnancy.", "content": "A ten-year survey of ectopic pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991584"}
{"pmid": "20991585", "title": "Pudendal nerve block in obstetrics (perineal field block).", "content": "Pudendal nerve block in obstetrics (perineal field block).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991585"}
{"pmid": "20991586", "title": "Contact dermatitis from morphine; a series of cases among workers in a drug factory.", "content": "Contact dermatitis from morphine; a series of cases among workers in a drug factory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991586"}
{"pmid": "20991587", "title": "Deodorants; facts and fallacies.", "content": "Deodorants; facts and fallacies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991587"}
{"pmid": "20991588", "title": "Speech pathology as managed in a children's hospital.", "content": "Speech pathology as managed in a children's hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991588"}
{"pmid": "20991589", "title": "Treatment of urinary tract infections.", "content": "Treatment of urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991589"}
{"pmid": "20991590", "title": "BASIC requirements of a department of clinical pathology of a modern hospital.", "content": "BASIC requirements of a department of clinical pathology of a modern hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991590"}
{"pmid": "20991591", "title": "Nutritional problems in hot weather 1683-6.", "content": "Nutritional problems in hot weather 1683-6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991591"}
{"pmid": "20991592", "title": "The acute abdomen.", "content": "The acute abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991592"}
{"pmid": "20991593", "title": "Adiposity.", "content": "Adiposity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991593"}
{"pmid": "20991599", "title": "Treatment and rehabilitation of men with damage of the brain.", "content": "Treatment and rehabilitation of men with damage of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991599"}
{"pmid": "20991600", "title": "Guard for intratracheal tube.", "content": "Guard for intratracheal tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991600"}
{"pmid": "20991601", "title": "The methylene blue test for bilirubinuria; clinical and spectrophotometric observations.", "content": "The methylene blue test for bilirubinuria; clinical and spectrophotometric observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991601"}
{"pmid": "20991602", "title": "Physiology of vitamin K and prothrombin level in the blood.", "content": "Physiology of vitamin K and prothrombin level in the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991602"}
{"pmid": "20991604", "title": "Diagnosis and treatment of the anemias.", "content": "Diagnosis and treatment of the anemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991604"}
{"pmid": "20991603", "title": "The initial letters of the De humani corporis fabrica.", "content": "The initial letters of the De humani corporis fabrica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991603"}
{"pmid": "20991605", "title": "Barbiturates and their clinical uses.", "content": "Barbiturates and their clinical uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991605"}
{"pmid": "20991632", "title": "Transthoracic resection of the esophagus for carcinoma.", "content": "Transthoracic resection of the esophagus for carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991632"}
{"pmid": "20991633", "title": "Colorado's laboratory approval program.", "content": "Colorado's laboratory approval program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991633"}
{"pmid": "20991634", "title": "Serum sickness-like reactions from penicillin.", "content": "Serum sickness-like reactions from penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991634"}
{"pmid": "20991635", "title": "Statement made before the Senate Committee on Education and Labor.", "content": "Statement made before the Senate Committee on Education and Labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991635"}
{"pmid": "20991636", "title": "Cardio-vascular disease in the Bantu and coloured races of South Africa; incidence, pathology and general features.", "content": "Cardio-vascular disease in the Bantu and coloured races of South Africa; incidence, pathology and general features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991636"}
{"pmid": "20991637", "title": "Cardio-vascular disease in the Bantu and coloured races of South Africa; congenital heart disease.", "content": "Cardio-vascular disease in the Bantu and coloured races of South Africa; congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991637"}
{"pmid": "20991638", "title": "Cardio-vascular disease in the Bantu and coloured races of South Africa; rheumatic heart disease.", "content": "Cardio-vascular disease in the Bantu and coloured races of South Africa; rheumatic heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991638"}
{"pmid": "20991639", "title": "The erythrocyte sedimentation rate in jaundice.", "content": "The erythrocyte sedimentation rate in jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991639"}
{"pmid": "20991640", "title": "The physique of American, Canadian, English and South African school children.", "content": "The physique of American, Canadian, English and South African school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991640"}
{"pmid": "20991642", "title": "The chromosome complement of Elephantulus.", "content": "The chromosome complement of Elephantulus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991642"}
{"pmid": "20991641", "title": "The role of the theca cell in irregularities of the baboon menstrual cycle.", "content": "The role of the theca cell in irregularities of the baboon menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991641"}
{"pmid": "20991643", "title": "The exocrine pancreatic tissue of seven teleosts.", "content": "The exocrine pancreatic tissue of seven teleosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991643"}
{"pmid": "20991644", "title": "The corpus luteum of Elephantulus during pregnancy; its form and its function.", "content": "The corpus luteum of Elephantulus during pregnancy; its form and its function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991644"}
{"pmid": "20991645", "title": "The reactions of the uterine blood vessels before, during and after pregnancy in Elephantulus.", "content": "The reactions of the uterine blood vessels before, during and after pregnancy in Elephantulus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991645"}
{"pmid": "20991646", "title": "Health centre practice, promotive health services and the development of the health centres scheme.", "content": "Health centre practice, promotive health services and the development of the health centres scheme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991646"}
{"pmid": "20991647", "title": "Annual report from the Department of Anaesthesia, Addington Hospital, Durban, 1945.", "content": "Annual report from the Department of Anaesthesia, Addington Hospital, Durban, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991647"}
{"pmid": "20991648", "title": "The distribution of the virus of poliomyelitis in a sewage purification works in Johannesburg.", "content": "The distribution of the virus of poliomyelitis in a sewage purification works in Johannesburg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991648"}
{"pmid": "20991649", "title": "An analysis of the medical and social conditions of native children attending Groote Schuur Hospital Paediatric Out-Patient Department.", "content": "An analysis of the medical and social conditions of native children attending Groote Schuur Hospital Paediatric Out-Patient Department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991649"}
{"pmid": "20991650", "title": "Report of 125 consecutive injuries treated with the first-aid application of sulphanilamide crystals.", "content": "Report of 125 consecutive injuries treated with the first-aid application of sulphanilamide crystals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991650"}
{"pmid": "20991651", "title": "EVIDENCE from the Negotiating Committee of the Federal Council of the Medical Association of South Africa on the draft ordinance to amend the law relating to hospitals in the Cape Province.", "content": "EVIDENCE from the Negotiating Committee of the Federal Council of the Medical Association of South Africa on the draft ordinance to amend the law relating to hospitals in the Cape Province.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991651"}
{"pmid": "20991674", "title": "Surgical treatment of carcinoma of the pancreas and ampulla of Vater.", "content": "Surgical treatment of carcinoma of the pancreas and ampulla of Vater.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991674"}
{"pmid": "20991675", "title": "Benadryl, its therapeutic value in allergy.", "content": "Benadryl, its therapeutic value in allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991675"}
{"pmid": "20991676", "title": "The Rh factor: analysis of a routine Rh testing service.", "content": "The Rh factor: analysis of a routine Rh testing service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991676"}
{"pmid": "20991677", "title": "Recent advances in Rh testing.", "content": "Recent advances in Rh testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991677"}
{"pmid": "20991678", "title": "Penicillin in the treatment of chronic osteomyelitis.", "content": "Penicillin in the treatment of chronic osteomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991678"}
{"pmid": "20991679", "title": "The history of psychiatry in relation to its present place in medicine.", "content": "The history of psychiatry in relation to its present place in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991679"}
{"pmid": "20991680", "title": "On mice or men?", "content": "On mice or men?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991680"}
{"pmid": "20991681", "title": "Effects of use and disuse on nerve and muscle.", "content": "Effects of use and disuse on nerve and muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991681"}
{"pmid": "20991682", "title": "Some causes of death during anaesthesia.", "content": "Some causes of death during anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991682"}
{"pmid": "20991683", "title": "Some experience in an isolation block of a general hospital in the Middle East.", "content": "Some experience in an isolation block of a general hospital in the Middle East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991683"}
{"pmid": "20991684", "title": "Careers in dentistry.", "content": "Careers in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991684"}
{"pmid": "20991685", "title": "The management and results of war wounds of the abdomen, 1944.", "content": "The management and results of war wounds of the abdomen, 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991685"}
{"pmid": "20991686", "title": "Abdominal injuries in battle casualties.", "content": "Abdominal injuries in battle casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991686"}
{"pmid": "20991687", "title": "An adventure with the iron lung.", "content": "An adventure with the iron lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991687"}
{"pmid": "20991688", "title": "HAVING t. b. in comfort.", "content": "HAVING t. b. in comfort.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991688"}
{"pmid": "20991689", "title": "Surgical experiences in P. o. W. hospitals in Germany.", "content": "Surgical experiences in P. o. W. hospitals in Germany.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991689"}
{"pmid": "20991690", "title": "Acute haemolytic anaemia following sulphonamides.", "content": "Acute haemolytic anaemia following sulphonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991690"}
{"pmid": "20991696", "title": "Penicillin in 21 Army group.", "content": "Penicillin in 21 Army group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991696"}
{"pmid": "20991697", "title": "MEDICAL care.", "content": "MEDICAL care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991697"}
{"pmid": "20991698", "title": "Recapitulation of medical care.", "content": "Recapitulation of medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991698"}
{"pmid": "20991705", "title": "Visual education and the motion picture industry.", "content": "Visual education and the motion picture industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991705"}
{"pmid": "20991700", "title": "Anti-Rh human sera preserved with merthiolate.", "content": "Anti-Rh human sera preserved with merthiolate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991700"}
{"pmid": "20991711", "title": "Temporary immunity in alfalfa ordinarily susceptible to attack by the pea aphid.", "content": "Temporary immunity in alfalfa ordinarily susceptible to attack by the pea aphid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991711"}
{"pmid": "20991699", "title": "Scientific method in the evolution of new drugs; active patches of native proteins.", "content": "Scientific method in the evolution of new drugs; active patches of native proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991699"}
{"pmid": "20991712", "title": "Yellow wilt of sugar beet in Argentina.", "content": "Yellow wilt of sugar beet in Argentina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991712"}
{"pmid": "20991713", "title": "The effect of dairy factory drainage upon the quality of streams in Taranaki.", "content": "The effect of dairy factory drainage upon the quality of streams in Taranaki.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991713"}
{"pmid": "20991701", "title": "Emulsions and emulsifying agents with special reference to D. D. T.", "content": "Emulsions and emulsifying agents with special reference to D. D. T.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991701"}
{"pmid": "20991714", "title": "Fluorine in New Zealand soils.", "content": "Fluorine in New Zealand soils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991714"}
{"pmid": "20991704", "title": "Uric acid in birds' feathers.", "content": "Uric acid in birds' feathers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991704"}
{"pmid": "20991703", "title": "The laws of nature in the light of modern physics and biology.", "content": "The laws of nature in the light of modern physics and biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991703"}
{"pmid": "20991715", "title": "New Zealand seaweed for agar manufacture; review of supplies.", "content": "New Zealand seaweed for agar manufacture; review of supplies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991715"}
{"pmid": "20991702", "title": "Aviation medicine.", "content": "Aviation medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991702"}
{"pmid": "20991716", "title": "A note on rearing Anobium punctatum de Geer.", "content": "A note on rearing Anobium punctatum de Geer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991716"}
{"pmid": "20991717", "title": "Alkaloids of the Leguminosae; alkaloids of Cytisus canariensis, C. stenopetalus, and allied species.", "content": "Alkaloids of the Leguminosae; alkaloids of Cytisus canariensis, C. stenopetalus, and allied species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991717"}
{"pmid": "20991718", "title": "Alkaloids of Cytisus monspessulanus L.", "content": "Alkaloids of Cytisus monspessulanus L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991718"}
{"pmid": "20991719", "title": "INTERNATIONAL control of atomic energy.", "content": "INTERNATIONAL control of atomic energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991719"}
{"pmid": "20991720", "title": "Tropical medicine in the British Empire.", "content": "Tropical medicine in the British Empire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991720"}
{"pmid": "20991722", "title": "Significance of the Australopithecinae.", "content": "Significance of the Australopithecinae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991722"}
{"pmid": "20991721", "title": "Radio meteorology; influence of the atmosphere on the propagation of ultra-short radio waves.", "content": "Radio meteorology; influence of the atmosphere on the propagation of ultra-short radio waves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991721"}
{"pmid": "20991723", "title": "X-ray examination of sucrose.", "content": "X-ray examination of sucrose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991723"}
{"pmid": "20991724", "title": "Internal photo-electric effect and band spectra in proteins.", "content": "Internal photo-electric effect and band spectra in proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991724"}
{"pmid": "20991725", "title": "Spectrophotometric assay of vitamin A and the conversion factor.", "content": "Spectrophotometric assay of vitamin A and the conversion factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991725"}
{"pmid": "20991726", "title": "Symbiosis between myxobacteria and nitrifying bacteria.", "content": "Symbiosis between myxobacteria and nitrifying bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991726"}
{"pmid": "20991727", "title": "Successful feeding experiments with an adult trombiculid mite (order Acarina).", "content": "Successful feeding experiments with an adult trombiculid mite (order Acarina).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991727"}
{"pmid": "20991728", "title": "Misuse of the term evolution.", "content": "Misuse of the term evolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991728"}
{"pmid": "20991729", "title": "SPECTROSCOPIC analysis.", "content": "SPECTROSCOPIC analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991729"}
{"pmid": "20991730", "title": "Anthropology on the continent of Europe in war-time.", "content": "Anthropology on the continent of Europe in war-time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991730"}
{"pmid": "20991731", "title": "INTERNATIONAL Academy of the History of Science.", "content": "INTERNATIONAL Academy of the History of Science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991731"}
{"pmid": "20991732", "title": "New synthetic contact insecticides.", "content": "New synthetic contact insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991732"}
{"pmid": "20991733", "title": "Polarographic behaviour of adenine.", "content": "Polarographic behaviour of adenine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991733"}
{"pmid": "20991734", "title": "Presence of fibrinogen in the yolk sac content of rabbits.", "content": "Presence of fibrinogen in the yolk sac content of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991734"}
{"pmid": "20991735", "title": "Magnesium chlorosis of tomatoes.", "content": "Magnesium chlorosis of tomatoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991735"}
{"pmid": "20991736", "title": "New evidence for the formation of molecular complexes in monolayers by penetration.", "content": "New evidence for the formation of molecular complexes in monolayers by penetration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991736"}
{"pmid": "20991737", "title": "Electric induction in molecules and the polarity of the C-H bond.", "content": "Electric induction in molecules and the polarity of the C-H bond.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991737"}
{"pmid": "20991738", "title": "Surface area determination.", "content": "Surface area determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991738"}
{"pmid": "20991739", "title": "Experimental data and sufficient accuracy.", "content": "Experimental data and sufficient accuracy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991739"}
{"pmid": "20991740", "title": "Science in Egypt.", "content": "Science in Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991740"}
{"pmid": "20991741", "title": "Supersonic cries of bats.", "content": "Supersonic cries of bats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991741"}
{"pmid": "20991742", "title": "Plant tumours induced by the combined action of wounds and virus.", "content": "Plant tumours induced by the combined action of wounds and virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991742"}
{"pmid": "20991743", "title": "The protein of fruits.", "content": "The protein of fruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991743"}
{"pmid": "20991744", "title": "Changes occurring in Bacillus fusiformis during the application of penicillin.", "content": "Changes occurring in Bacillus fusiformis during the application of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991744"}
{"pmid": "20991745", "title": "Biological activity of vitamin A acid.", "content": "Biological activity of vitamin A acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991745"}
{"pmid": "20991746", "title": "High-frequency discharge as an ion source.", "content": "High-frequency discharge as an ion source.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991746"}
{"pmid": "20991747", "title": "Japanese men of science in Malaya during Japanese occupation.", "content": "Japanese men of science in Malaya during Japanese occupation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991747"}
{"pmid": "20991748", "title": "Rhubarb leaves as a feeding-stuff for rabbits.", "content": "Rhubarb leaves as a feeding-stuff for rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991748"}
{"pmid": "20991749", "title": "Fish mortality due to a brown flagellate.", "content": "Fish mortality due to a brown flagellate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991749"}
{"pmid": "20991750", "title": "An automatic sample changer to be used for measuring radioactive samples.", "content": "An automatic sample changer to be used for measuring radioactive samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991750"}
{"pmid": "20991752", "title": "Measurement of surface potential or contact potential differences.", "content": "Measurement of surface potential or contact potential differences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991752"}
{"pmid": "20991751", "title": "Design of beta-ray and gamma-ray Geiger-Müller counters.", "content": "Design of beta-ray and gamma-ray Geiger-Müller counters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991751"}
{"pmid": "20991753", "title": "The measurement of thermal radiation at microwave frequencies.", "content": "The measurement of thermal radiation at microwave frequencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991753"}
{"pmid": "20991754", "title": "Counting rate and frequency meter.", "content": "Counting rate and frequency meter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991754"}
{"pmid": "20991755", "title": "TEMPERATURE regulator.", "content": "TEMPERATURE regulator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991755"}
{"pmid": "20991756", "title": "DOES alcohol aid artistic ability?", "content": "DOES alcohol aid artistic ability?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991756"}
{"pmid": "20991757", "title": "Sociological factors in the use of alcohol.", "content": "Sociological factors in the use of alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991757"}
{"pmid": "20991758", "title": "Army staff in Sweden gives scientific instruction regarding alcohol.", "content": "Army staff in Sweden gives scientific instruction regarding alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991758"}
{"pmid": "20991759", "title": "Alcoholic culture; should it be retained?", "content": "Alcoholic culture; should it be retained?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991759"}
{"pmid": "20991760", "title": "Spinal cord circulation in poliomyelitis.", "content": "Spinal cord circulation in poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991760"}
{"pmid": "20991761", "title": "The effect of thiouracil and thyroactive substances on mouse susceptibility to poliomyelitis virus.", "content": "The effect of thiouracil and thyroactive substances on mouse susceptibility to poliomyelitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991761"}
{"pmid": "20991762", "title": "The failure of poliomyelitis virus to grow in certain protozoa of sewage.", "content": "The failure of poliomyelitis virus to grow in certain protozoa of sewage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991762"}
{"pmid": "20991763", "title": "Influence of anesthesia on experimental western equine encephalomyelitis.", "content": "Influence of anesthesia on experimental western equine encephalomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991763"}
{"pmid": "20991764", "title": "Built-in jacks for plaster casts.", "content": "Built-in jacks for plaster casts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991764"}
{"pmid": "20991765", "title": "IMPROVED method for quantitative impregnation of textiles with germicidal emulsificable oils.", "content": "IMPROVED method for quantitative impregnation of textiles with germicidal emulsificable oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991765"}
{"pmid": "20991767", "title": "Abbreviations of generic names.", "content": "Abbreviations of generic names.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991767"}
{"pmid": "20991766", "title": "A multiple light source microscope.", "content": "A multiple light source microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991766"}
{"pmid": "20991768", "title": "Survival time of hypertensive rats receiving fish-oil extracts.", "content": "Survival time of hypertensive rats receiving fish-oil extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991768"}
{"pmid": "20991769", "title": "The orientation of an undergraduate medical curriculum.", "content": "The orientation of an undergraduate medical curriculum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991769"}
{"pmid": "20991770", "title": "DDT as a marine antifouling agent.", "content": "DDT as a marine antifouling agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991770"}
{"pmid": "20991771", "title": "The therapeutic effect of folic acid in tropical sprue.", "content": "The therapeutic effect of folic acid in tropical sprue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991771"}
{"pmid": "20991772", "title": "Food of nymphs and adults of Neoschöngastia indica (Hirst 1915).", "content": "Food of nymphs and adults of Neoschöngastia indica (Hirst 1915).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991772"}
{"pmid": "20991773", "title": "Period of effective weed control by the use of 2,4-dichlorophenoxyacetic acid.", "content": "Period of effective weed control by the use of 2,4-dichlorophenoxyacetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991773"}
{"pmid": "20991774", "title": "Determination of penicillin K by partition chromatography.", "content": "Determination of penicillin K by partition chromatography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991774"}
{"pmid": "20991775", "title": "Sulfa drugs and the treatment of furunculosis in trout.", "content": "Sulfa drugs and the treatment of furunculosis in trout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991775"}
{"pmid": "20991776", "title": "Inactivation of hypertensin.", "content": "Inactivation of hypertensin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991776"}
{"pmid": "20991777", "title": "A note on the meaning of normal.", "content": "A note on the meaning of normal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991777"}
{"pmid": "20991778", "title": "The physiological and biochemical standardization of the dog.", "content": "The physiological and biochemical standardization of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991778"}
{"pmid": "20991779", "title": "Some practical aspects of selecting and maintaining dogs for medical research.", "content": "Some practical aspects of selecting and maintaining dogs for medical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991779"}
{"pmid": "20991780", "title": "Electrical measurements of mental activities in man.", "content": "Electrical measurements of mental activities in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991780"}
{"pmid": "20991781", "title": "The study of cultural patterns in European nations.", "content": "The study of cultural patterns in European nations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991781"}
{"pmid": "20991782", "title": "Recent advances in medicine and their application to mental deficiency.", "content": "Recent advances in medicine and their application to mental deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991782"}
{"pmid": "20991783", "title": "Water supply and sewage treatment for mental institutions.", "content": "Water supply and sewage treatment for mental institutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991783"}
{"pmid": "20991784", "title": "The problem of control of tuberculosis in mental hospitals with reduced personnel.", "content": "The problem of control of tuberculosis in mental hospitals with reduced personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991784"}
{"pmid": "20991785", "title": "X-ray examination of the chest in mental deficiency.", "content": "X-ray examination of the chest in mental deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991785"}
{"pmid": "20991786", "title": "The significance of practice effect upon readministration of the Grace Arthur Performance Scale to high grade mentally deficient children.", "content": "The significance of practice effect upon readministration of the Grace Arthur Performance Scale to high grade mentally deficient children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991786"}
{"pmid": "20991787", "title": "Some aspects of idiocy in mongolism.", "content": "Some aspects of idiocy in mongolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991787"}
{"pmid": "20991788", "title": "Unworthy parental attitudes toward mental defectives.", "content": "Unworthy parental attitudes toward mental defectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991788"}
{"pmid": "20991789", "title": "The relationship between the psychologist and the teacher.", "content": "The relationship between the psychologist and the teacher.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991789"}
{"pmid": "20991790", "title": "The adjustment of moron males in a group placement.", "content": "The adjustment of moron males in a group placement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991790"}
{"pmid": "20991791", "title": "Community adjustment of the moron.", "content": "Community adjustment of the moron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991791"}
{"pmid": "20991793", "title": "Public institutions for mental defectives, their organization and equipment.", "content": "Public institutions for mental defectives, their organization and equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991793"}
{"pmid": "20991792", "title": "A study of cases discharged from the Laconia State School from July 1, 1924, to July 1, 1934.", "content": "A study of cases discharged from the Laconia State School from July 1, 1924, to July 1, 1934.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991792"}
{"pmid": "20991794", "title": "Trends in the institutional care for the mentally defective.", "content": "Trends in the institutional care for the mentally defective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991794"}
{"pmid": "20991795", "title": "The institutional program for the mentally deficient in Ohio.", "content": "The institutional program for the mentally deficient in Ohio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991795"}
{"pmid": "20991796", "title": "A complete program for training of institutional inmates.", "content": "A complete program for training of institutional inmates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991796"}
{"pmid": "20991797", "title": "An administrative structure for an institution for mentally deficient.", "content": "An administrative structure for an institution for mentally deficient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991797"}
{"pmid": "20991798", "title": "Recent trends in functioning programs for the mentally deficient.", "content": "Recent trends in functioning programs for the mentally deficient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991798"}
{"pmid": "20991799", "title": "The Ozeretzky scale.", "content": "The Ozeretzky scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991799"}
{"pmid": "20991809", "title": "Origin of the ventral external arcuate fibers and their continuity with the striae medullares of the fourth ventricle of man.", "content": "Origin of the ventral external arcuate fibers and their continuity with the striae medullares of the fourth ventricle of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991809"}
{"pmid": "20991808", "title": "Connections of the cerebral cortex; the albino rat; structure of the cortical areas.", "content": "Connections of the cerebral cortex; the albino rat; structure of the cortical areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991808"}
{"pmid": "20991810", "title": "The regio occipitalis of the lorisiform lemuroid Galago demidovii.", "content": "The regio occipitalis of the lorisiform lemuroid Galago demidovii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991810"}
{"pmid": "20991811", "title": "The development of the forebrain of the American water snake (Natrix sipedon).", "content": "The development of the forebrain of the American water snake (Natrix sipedon).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991811"}
{"pmid": "20991812", "title": "An analysis of the inferior alveolar and mental nerves in the cat.", "content": "An analysis of the inferior alveolar and mental nerves in the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991812"}
{"pmid": "20991813", "title": "Electromyographic studies of muscular coordination on stimulation of motor cortex.", "content": "Electromyographic studies of muscular coordination on stimulation of motor cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991813"}
{"pmid": "20991814", "title": "Centrifugal deterioration of asphyxiated peripheral nerve.", "content": "Centrifugal deterioration of asphyxiated peripheral nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991814"}
{"pmid": "20991815", "title": "Hypothalamic regulation of sleep in rats; an experimental study.", "content": "Hypothalamic regulation of sleep in rats; an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991815"}
{"pmid": "20991817", "title": "Mechanism of pupillary dilatation elicited by cortical stimulation.", "content": "Mechanism of pupillary dilatation elicited by cortical stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991817"}
{"pmid": "20991816", "title": "Frequency of centripetal stimulation in inhibition and facilitation of the knee-jerk.", "content": "Frequency of centripetal stimulation in inhibition and facilitation of the knee-jerk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991816"}
{"pmid": "20991818", "title": "Inhibition at the nerve muscle junction in crustacea.", "content": "Inhibition at the nerve muscle junction in crustacea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991818"}
{"pmid": "20991819", "title": "Neuroanatomy.", "content": "Neuroanatomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991819"}
{"pmid": "20991820", "title": "Development of the nervous system.", "content": "Development of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991820"}
{"pmid": "20991822", "title": "Chemical aspects of the transmission of nerve impulses.", "content": "Chemical aspects of the transmission of nerve impulses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991822"}
{"pmid": "20991821", "title": "General neurophysiology.", "content": "General neurophysiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991821"}
{"pmid": "20991823", "title": "Regional physiology of the central nervous system.", "content": "Regional physiology of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991823"}
{"pmid": "20991824", "title": "Vision.", "content": "Vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991824"}
{"pmid": "20991825", "title": "Hearing and equilibrium.", "content": "Hearing and equilibrium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991825"}
{"pmid": "20991827", "title": "Neuropathology.", "content": "Neuropathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991827"}
{"pmid": "20991828", "title": "Regeneration and repair of peripheral nerves (morphological and experimental aspects).", "content": "Regeneration and repair of peripheral nerves (morphological and experimental aspects).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991828"}
{"pmid": "20991826", "title": "The conditional reflex.", "content": "The conditional reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991826"}
{"pmid": "20991829", "title": "Pharmacology of the nervous system.", "content": "Pharmacology of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991829"}
{"pmid": "20991830", "title": "The effect of antibiotic substances on the central nervous system.", "content": "The effect of antibiotic substances on the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991830"}
{"pmid": "20991831", "title": "Clinical neurology.", "content": "Clinical neurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991831"}
{"pmid": "20991832", "title": "Otoneurology.", "content": "Otoneurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991832"}
{"pmid": "20991834", "title": "Neurosyphilis.", "content": "Neurosyphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991834"}
{"pmid": "20991833", "title": "Ophthalmoneurology.", "content": "Ophthalmoneurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991833"}
{"pmid": "20991835", "title": "Epilepsy.", "content": "Epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991835"}
{"pmid": "20991836", "title": "The autonomic nervous system.", "content": "The autonomic nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991836"}
{"pmid": "20991837", "title": "Endocrinology.", "content": "Endocrinology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991837"}
{"pmid": "20991839", "title": "Cerebrospinal fluid.", "content": "Cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991839"}
{"pmid": "20991838", "title": "Neurologic and psychologic aspects of allergy.", "content": "Neurologic and psychologic aspects of allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991838"}
{"pmid": "20991840", "title": "Roentgenology of the skull and central nervous system.", "content": "Roentgenology of the skull and central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991840"}
{"pmid": "20991841", "title": "Electroencephalography.", "content": "Electroencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991841"}
{"pmid": "20991843", "title": "Peripheral nerve injuries (diagnosis and treatment).", "content": "Peripheral nerve injuries (diagnosis and treatment).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991843"}
{"pmid": "20991842", "title": "Penicillin and streptomycin therapy in relation to neurology.", "content": "Penicillin and streptomycin therapy in relation to neurology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991842"}
{"pmid": "20991844", "title": "Surgery of spinal cord and spinal column.", "content": "Surgery of spinal cord and spinal column.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991844"}
{"pmid": "20991845", "title": "Cerebral trauma.", "content": "Cerebral trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991845"}
{"pmid": "20991846", "title": "Surgical infections of the brain and its coverings.", "content": "Surgical infections of the brain and its coverings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991846"}
{"pmid": "20991847", "title": "Brain tumors.", "content": "Brain tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991847"}
{"pmid": "20991848", "title": "The treatment of motor and sensory disturbances.", "content": "The treatment of motor and sensory disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991848"}
{"pmid": "20991849", "title": "General clinical psychiatry.", "content": "General clinical psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991849"}
{"pmid": "20991850", "title": "Child psychiatry.", "content": "Child psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991850"}
{"pmid": "20991851", "title": "War neuroses.", "content": "War neuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991851"}
{"pmid": "20991852", "title": "Psychosomatic medicine.", "content": "Psychosomatic medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991852"}
{"pmid": "20991853", "title": "The Rorschach test and other projective technics.", "content": "The Rorschach test and other projective technics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991853"}
{"pmid": "20991854", "title": "Shock therapy.", "content": "Shock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991854"}
{"pmid": "20991855", "title": "Psychosurgery.", "content": "Psychosurgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991855"}
{"pmid": "20991856", "title": "Group psychotherapy.", "content": "Group psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991856"}
{"pmid": "20991857", "title": "Psychoanalysis.", "content": "Psychoanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991857"}
{"pmid": "20991858", "title": "Freud and Spinoza.", "content": "Freud and Spinoza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991858"}
{"pmid": "20991859", "title": "Adequacy and conservation in adjustment.", "content": "Adequacy and conservation in adjustment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991859"}
{"pmid": "20991860", "title": "The act of deleting and other findings in writings of neurotics.", "content": "The act of deleting and other findings in writings of neurotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991860"}
{"pmid": "20991861", "title": "The culture of the Army clerk.", "content": "The culture of the Army clerk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991861"}
{"pmid": "20991862", "title": "A note on anti-semitism.", "content": "A note on anti-semitism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991862"}
{"pmid": "20991863", "title": "Know not what they do; a psychiatric étude.", "content": "Know not what they do; a psychiatric étude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991863"}
{"pmid": "20991864", "title": "Racism and social action.", "content": "Racism and social action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991864"}
{"pmid": "20991866", "title": "ATOM bomb and the nurse.", "content": "ATOM bomb and the nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991866"}
{"pmid": "20991865", "title": "Rehabilitation of the handicapped; the role of the industrial nurse.", "content": "Rehabilitation of the handicapped; the role of the industrial nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991865"}
{"pmid": "20991867", "title": "Control of infectious diseases; artificial immunity.", "content": "Control of infectious diseases; artificial immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991867"}
{"pmid": "20991868", "title": "Family health; methods of improvement beginning in the home.", "content": "Family health; methods of improvement beginning in the home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991868"}
{"pmid": "20991869", "title": "British military hospitals and convalescent depots.", "content": "British military hospitals and convalescent depots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991869"}
{"pmid": "20991870", "title": "Failures in teaching.", "content": "Failures in teaching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991870"}
{"pmid": "20991871", "title": "Perforated pyloric ulcer with chest complications.", "content": "Perforated pyloric ulcer with chest complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991871"}
{"pmid": "20991872", "title": "The National Health Service Bill.", "content": "The National Health Service Bill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991872"}
{"pmid": "20991873", "title": "Fractured base of skull complicated by pneumococcal meningitis.", "content": "Fractured base of skull complicated by pneumococcal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991873"}
{"pmid": "20991874", "title": "Recent advances in ophthalmology.", "content": "Recent advances in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991874"}
{"pmid": "20991875", "title": "Epilepsy; what can be done about it?", "content": "Epilepsy; what can be done about it?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991875"}
{"pmid": "20991876", "title": "Drug addiction.", "content": "Drug addiction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991876"}
{"pmid": "20991877", "title": "Dr. Duchenne wizard of electrotherapy.", "content": "Dr. Duchenne wizard of electrotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991877"}
{"pmid": "20991878", "title": "Nurse shortages can be overcome.", "content": "Nurse shortages can be overcome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991878"}
{"pmid": "20991879", "title": "Nursing homes for the aged.", "content": "Nursing homes for the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991879"}
{"pmid": "20991880", "title": "The scleral-resection (eyeball-shortening) operation.", "content": "The scleral-resection (eyeball-shortening) operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991880"}
{"pmid": "20991881", "title": "Retinal hemorrhage as seen in an atomic-bomb casualty.", "content": "Retinal hemorrhage as seen in an atomic-bomb casualty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991881"}
{"pmid": "20991882", "title": "Some effects of vitamin-A deficiency on the eye of the rabbit.", "content": "Some effects of vitamin-A deficiency on the eye of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991882"}
{"pmid": "20991883", "title": "The management of intraocular foreign bodies in military practice.", "content": "The management of intraocular foreign bodies in military practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991883"}
{"pmid": "20991884", "title": "The effect of sunlight on dark adaptation.", "content": "The effect of sunlight on dark adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991884"}
{"pmid": "20991885", "title": "Observations on the Vossius ring.", "content": "Observations on the Vossius ring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991885"}
{"pmid": "20991886", "title": "Saccular prolapse of the vitreous body.", "content": "Saccular prolapse of the vitreous body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991886"}
{"pmid": "20991887", "title": "Cyclodialysis in the treatment of glaucoma.", "content": "Cyclodialysis in the treatment of glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991887"}
{"pmid": "20991888", "title": "Unaided visual acuities correlated with refractive errors.", "content": "Unaided visual acuities correlated with refractive errors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991888"}
{"pmid": "20991889", "title": "A method of evisceration of the eyeball.", "content": "A method of evisceration of the eyeball.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991889"}
{"pmid": "20991890", "title": "Scleromalacia.", "content": "Scleromalacia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991890"}
{"pmid": "20991891", "title": "Epidermoid carcinoma of the cornea.", "content": "Epidermoid carcinoma of the cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991891"}
{"pmid": "20991892", "title": "Choice of grafts for orbital reconstruction.", "content": "Choice of grafts for orbital reconstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991892"}
{"pmid": "20991893", "title": "Retinal detachment secondary to conglomerate tubercle of the choroid.", "content": "Retinal detachment secondary to conglomerate tubercle of the choroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991893"}
{"pmid": "20991894", "title": "Injury to the left eyebrow associated with severe visual loss.", "content": "Injury to the left eyebrow associated with severe visual loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991894"}
{"pmid": "20991895", "title": "The corrosion of sharp-edged ophthalmic instruments.", "content": "The corrosion of sharp-edged ophthalmic instruments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991895"}
{"pmid": "20991896", "title": "An artery in the canal of Schlemm.", "content": "An artery in the canal of Schlemm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991896"}
{"pmid": "20991897", "title": "Dacryocystorhinostomy; a simplified method.", "content": "Dacryocystorhinostomy; a simplified method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991897"}
{"pmid": "20991898", "title": "Symposium on congenital anomalies of the eye following rubella.", "content": "Symposium on congenital anomalies of the eye following rubella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991898"}
{"pmid": "20991899", "title": "Congenital stenosis treated by plastic dacryorhinostomy.", "content": "Congenital stenosis treated by plastic dacryorhinostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991899"}
{"pmid": "20991900", "title": "Pigmentary degeneration of the retina with cataracts and deafness.", "content": "Pigmentary degeneration of the retina with cataracts and deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991900"}
{"pmid": "20991901", "title": "Nationalized ophthalmology in Britain.", "content": "Nationalized ophthalmology in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991901"}
{"pmid": "20991902", "title": "Iridencleisis and Tenon's capsule.", "content": "Iridencleisis and Tenon's capsule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991902"}
{"pmid": "20991903", "title": "Comments on nystagmus with a review of five cases.", "content": "Comments on nystagmus with a review of five cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991903"}
{"pmid": "20991904", "title": "A chart for estimating visual acuity in pre-school children.", "content": "A chart for estimating visual acuity in pre-school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991904"}
{"pmid": "20991905", "title": "Improvement of color vision in 20 cases.", "content": "Improvement of color vision in 20 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991905"}
{"pmid": "20991935", "title": "Educating our eyes.", "content": "Educating our eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991935"}
{"pmid": "20991936", "title": "On infra-red sensitive phosphors.", "content": "On infra-red sensitive phosphors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991936"}
{"pmid": "20991937", "title": "Preparation and characteristics of zinc sulfide phosphors sensitive to infrared.", "content": "Preparation and characteristics of zinc sulfide phosphors sensitive to infrared.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991937"}
{"pmid": "20991938", "title": "Note on the effect of plate calibration errors in spectrographic analysis.", "content": "Note on the effect of plate calibration errors in spectrographic analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991938"}
{"pmid": "20991939", "title": "International names in colorimetry.", "content": "International names in colorimetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991939"}
{"pmid": "20991940", "title": "Statistical fluctuations in the temperature of a bolometer.", "content": "Statistical fluctuations in the temperature of a bolometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991940"}
{"pmid": "20991941", "title": "Some suggestions for the nomenclature of radiation.", "content": "Some suggestions for the nomenclature of radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991941"}
{"pmid": "20991942", "title": "On the rules for the correction of astigmatism.", "content": "On the rules for the correction of astigmatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991942"}
{"pmid": "20991962", "title": "The intranasal tearsac operation.", "content": "The intranasal tearsac operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991962"}
{"pmid": "20991963", "title": "Trauma and ocular pathology; a study in relations.", "content": "Trauma and ocular pathology; a study in relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991963"}
{"pmid": "20991964", "title": "Vasodilators in methyl alcohol poisoning.", "content": "Vasodilators in methyl alcohol poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991964"}
{"pmid": "20991965", "title": "Hygiene of the ear.", "content": "Hygiene of the ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991965"}
{"pmid": "20991966", "title": "Smoker's throat.", "content": "Smoker's throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991966"}
{"pmid": "20991967", "title": "Acoustic nerve tumor.", "content": "Acoustic nerve tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991967"}
{"pmid": "20991968", "title": "The function of the labyrinth.", "content": "The function of the labyrinth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991968"}
{"pmid": "20991969", "title": "Blast injury of the tympanic membrane.", "content": "Blast injury of the tympanic membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991969"}
{"pmid": "20991970", "title": "Two cases of petrositis and Gradenigo's syndrome, treated by conservative surgery and penicillin.", "content": "Two cases of petrositis and Gradenigo's syndrome, treated by conservative surgery and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991970"}
{"pmid": "20991971", "title": "Necrotizing arterial lesions resembling those of periarteritis nodosa and focal visceral necrosis following administration of sulfathiazole; report of a case.", "content": "Necrotizing arterial lesions resembling those of periarteritis nodosa and focal visceral necrosis following administration of sulfathiazole; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991971"}
{"pmid": "20991972", "title": "Hypersensitivity in the pathogenesis of the histopathologic changes associated with sulfonamide chemotherapy.", "content": "Hypersensitivity in the pathogenesis of the histopathologic changes associated with sulfonamide chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991972"}
{"pmid": "20991974", "title": "Experiments with jaagsiekte.", "content": "Experiments with jaagsiekte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991974"}
{"pmid": "20991973", "title": "The pathology of sulfonamide allergy in man.", "content": "The pathology of sulfonamide allergy in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991973"}
{"pmid": "20991975", "title": "Chronic leptomeningitis and ependymitis caused by Ustilago, probably U. zeae (corn smut).", "content": "Chronic leptomeningitis and ependymitis caused by Ustilago, probably U. zeae (corn smut).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991975"}
{"pmid": "20991976", "title": "Systemic infantile toxoplasmosis.", "content": "Systemic infantile toxoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991976"}
{"pmid": "20991977", "title": "Pathologic findings in the lungs of five cases from which influenza virus was isolated.", "content": "Pathologic findings in the lungs of five cases from which influenza virus was isolated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991977"}
{"pmid": "20991978", "title": "The significance of hyperemia around tumor implants.", "content": "The significance of hyperemia around tumor implants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991978"}
{"pmid": "20991979", "title": "Mediastinal chorionepithelioma in a male.", "content": "Mediastinal chorionepithelioma in a male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991979"}
{"pmid": "20991980", "title": "Medial hyperplasia in pulmonary arteries of cats.", "content": "Medial hyperplasia in pulmonary arteries of cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991980"}
{"pmid": "20991981", "title": "Cephalothoracopagus monosymmetros.", "content": "Cephalothoracopagus monosymmetros.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991981"}
{"pmid": "20991982", "title": "The effect of diet upon the ascorbic acid content of the liver in mice.", "content": "The effect of diet upon the ascorbic acid content of the liver in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991982"}
{"pmid": "20991983", "title": "Determination of coagulase and alpha-haemolysin production by staphylococci.", "content": "Determination of coagulase and alpha-haemolysin production by staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991983"}
{"pmid": "20991984", "title": "The virus content of plants suffering from tobacco mosaic.", "content": "The virus content of plants suffering from tobacco mosaic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991984"}
{"pmid": "20991985", "title": "Effect of penicillin combined with neoarsphenamine on the lesions and serological titre of experimental syphilis.", "content": "Effect of penicillin combined with neoarsphenamine on the lesions and serological titre of experimental syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991985"}
{"pmid": "20991986", "title": "Retesting of a strain (IF) of mice specially sensitive to carcinogenic agents applied to the skin.", "content": "Retesting of a strain (IF) of mice specially sensitive to carcinogenic agents applied to the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991986"}
{"pmid": "20991987", "title": "The incidence of Rh types in the British population.", "content": "The incidence of Rh types in the British population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991987"}
{"pmid": "20991988", "title": "The release of antibody by sensitized antigens.", "content": "The release of antibody by sensitized antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991988"}
{"pmid": "20991989", "title": "The preparation of pure flagellar antigens from Salmonella.", "content": "The preparation of pure flagellar antigens from Salmonella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991989"}
{"pmid": "20991990", "title": "A study of the prozones of the Salmonella.", "content": "A study of the prozones of the Salmonella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991990"}
{"pmid": "20991991", "title": "Congenital hernia of the diaphragm.", "content": "Congenital hernia of the diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991991"}
{"pmid": "20991992", "title": "Relation of ascorbic acid to effectiveness of iron therapy in children.", "content": "Relation of ascorbic acid to effectiveness of iron therapy in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991992"}
{"pmid": "20991994", "title": "Hypoprothrombinemia in infants with diarrhea.", "content": "Hypoprothrombinemia in infants with diarrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991994"}
{"pmid": "20991993", "title": "Fever produced by the oral administration of amino acids.", "content": "Fever produced by the oral administration of amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991993"}
{"pmid": "20991995", "title": "Significance of downward T waves in precordial leads of normal children.", "content": "Significance of downward T waves in precordial leads of normal children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991995"}
{"pmid": "20991996", "title": "Metabolic studies on rachitic infants.", "content": "Metabolic studies on rachitic infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991996"}
{"pmid": "20991997", "title": "Goat's milk as a source of bone-building minerals for infant feeding.", "content": "Goat's milk as a source of bone-building minerals for infant feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991997"}
{"pmid": "20991998", "title": "Aneurysm of the lower abdominal aorta with rupture in a sixteen month old infant.", "content": "Aneurysm of the lower abdominal aorta with rupture in a sixteen month old infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20991998"}
{"pmid": "20992003", "title": "Streptomycin in the treatment of influenzal meningitis.", "content": "Streptomycin in the treatment of influenzal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992003"}
{"pmid": "20992004", "title": "Influenzal meningitis; report of three cases treated with streptomycin and sulfadiazine.", "content": "Influenzal meningitis; report of three cases treated with streptomycin and sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992004"}
{"pmid": "20992005", "title": "Tridione; its use in convulsive and related disorders.", "content": "Tridione; its use in convulsive and related disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992005"}
{"pmid": "20992006", "title": "A comparison of the vitamin C in mothers and their newborn infants.", "content": "A comparison of the vitamin C in mothers and their newborn infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992006"}
{"pmid": "20992007", "title": "Diagnosis and management of severe infections in infants and children; a review of experiences since the introduction of sulfonamide therapy; staphylococcal empyema; the importance of pyopneumothorax as a complication.", "content": "Diagnosis and management of severe infections in infants and children; a review of experiences since the introduction of sulfonamide therapy; staphylococcal empyema; the importance of pyopneumothorax as a complication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992007"}
{"pmid": "20992008", "title": "Bilateral renal agenesis.", "content": "Bilateral renal agenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992008"}
{"pmid": "20992009", "title": "Laboratory and clinical criteria of rheumatic carditis in children.", "content": "Laboratory and clinical criteria of rheumatic carditis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992009"}
{"pmid": "20992010", "title": "Immunization against whooping cough.", "content": "Immunization against whooping cough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992010"}
{"pmid": "20992011", "title": "Craniopharyngiomas in children.", "content": "Craniopharyngiomas in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992011"}
{"pmid": "20992012", "title": "ACADEMY Study of Child Health Services.", "content": "ACADEMY Study of Child Health Services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992012"}
{"pmid": "20992023", "title": "A phytochemical study of Nereocystis luetkeana.", "content": "A phytochemical study of Nereocystis luetkeana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992023"}
{"pmid": "20992024", "title": "Rutin and capillary fragility.", "content": "Rutin and capillary fragility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992024"}
{"pmid": "20992028", "title": "Peacetime implications of biological warfare.", "content": "Peacetime implications of biological warfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992028"}
{"pmid": "20992027", "title": "The chemistry of some antibiotics.", "content": "The chemistry of some antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992027"}
{"pmid": "20992029", "title": "Restoration of waste alcohol.", "content": "Restoration of waste alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992029"}
{"pmid": "20992030", "title": "Conditions in colonial territories.", "content": "Conditions in colonial territories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992030"}
{"pmid": "20992031", "title": "Nomenclature of dermatological preparations.", "content": "Nomenclature of dermatological preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992031"}
{"pmid": "20992032", "title": "Glucose ingestion during severe anoxia.", "content": "Glucose ingestion during severe anoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992032"}
{"pmid": "20992033", "title": "The relation of the action potentials to mechanical activity in intestinal muscle.", "content": "The relation of the action potentials to mechanical activity in intestinal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992033"}
{"pmid": "20992034", "title": "Hypersensitivity to insulin in eviscerated hypophysectomized rats.", "content": "Hypersensitivity to insulin in eviscerated hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992034"}
{"pmid": "20992035", "title": "Exchanges of heat and tolerances to cold in men exposed to outdoor weather.", "content": "Exchanges of heat and tolerances to cold in men exposed to outdoor weather.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992035"}
{"pmid": "20992036", "title": "The tolerance of man to cold as affected by dietary modifications: high versus low intake of certain watersoluble vitamins.", "content": "The tolerance of man to cold as affected by dietary modifications: high versus low intake of certain watersoluble vitamins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992036"}
{"pmid": "20992037", "title": "Water intoxication and the electroencephalogram.", "content": "Water intoxication and the electroencephalogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992037"}
{"pmid": "20992038", "title": "Effect of epinephrine and physostigmine on the response of striated muscle to acetylcholine and potassium.", "content": "Effect of epinephrine and physostigmine on the response of striated muscle to acetylcholine and potassium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992038"}
{"pmid": "20992039", "title": "Some characteristics of peripheral visual performance.", "content": "Some characteristics of peripheral visual performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992039"}
{"pmid": "20992040", "title": "Bone growth in the rat as related to age and body weight.", "content": "Bone growth in the rat as related to age and body weight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992040"}
{"pmid": "20992041", "title": "Specific and non-specific nutritional effects as illustrated in bone.", "content": "Specific and non-specific nutritional effects as illustrated in bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992041"}
{"pmid": "20992042", "title": "The relationship between total heat exchange and blood flow in the hand at various ambient temperatures.", "content": "The relationship between total heat exchange and blood flow in the hand at various ambient temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992042"}
{"pmid": "20992043", "title": "Gastric emptying and intestinal absorption of dextrose solutions.", "content": "Gastric emptying and intestinal absorption of dextrose solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992043"}
{"pmid": "20992044", "title": "The effect of pulmonary ventilation on anoxemia.", "content": "The effect of pulmonary ventilation on anoxemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992044"}
{"pmid": "20992045", "title": "The development of peripheral visual acuity during the process of dark adaptation.", "content": "The development of peripheral visual acuity during the process of dark adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992045"}
{"pmid": "20992046", "title": "The effect of afferent impulses on hypothalamic potentials.", "content": "The effect of afferent impulses on hypothalamic potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992046"}
{"pmid": "20992051", "title": "Nondirective play therapy.", "content": "Nondirective play therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992051"}
{"pmid": "20992052", "title": "A battery of feeling and attitude scales for clinical use.", "content": "A battery of feeling and attitude scales for clinical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992052"}
{"pmid": "20992053", "title": "The personality makeup of emotionally unstable soldiers in relation to occupational adjustments.", "content": "The personality makeup of emotionally unstable soldiers in relation to occupational adjustments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992053"}
{"pmid": "20992054", "title": "A course in group psychotherapy; method, content and results.", "content": "A course in group psychotherapy; method, content and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992054"}
{"pmid": "20992047", "title": "Temperature regulation in three Central American mammals.", "content": "Temperature regulation in three Central American mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992047"}
{"pmid": "20992055", "title": "The validity and reliability of interpretation from autobiography and thematic apperception test.", "content": "The validity and reliability of interpretation from autobiography and thematic apperception test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992055"}
{"pmid": "20992056", "title": "A useful adjunct to the Minnesota personality inventory scoring and analysis.", "content": "A useful adjunct to the Minnesota personality inventory scoring and analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992056"}
{"pmid": "20992057", "title": "An application of the group Rorschach technique to the problem of achievement in college.", "content": "An application of the group Rorschach technique to the problem of achievement in college.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992057"}
{"pmid": "20992058", "title": "Directive psychotherapy; the psychology of satiation.", "content": "Directive psychotherapy; the psychology of satiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992058"}
{"pmid": "20992059", "title": "The hostility pattern.", "content": "The hostility pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992059"}
{"pmid": "20992060", "title": "A method of case transfer.", "content": "A method of case transfer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992060"}
{"pmid": "20992061", "title": "Report on a verbal projective technique.", "content": "Report on a verbal projective technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992061"}
{"pmid": "20992048", "title": "In vitro control of growing chick nerve fibers by applied electric currents.", "content": "In vitro control of growing chick nerve fibers by applied electric currents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992048"}
{"pmid": "20992062", "title": "Bernreuter patterns of a group of prison inmates.", "content": "Bernreuter patterns of a group of prison inmates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992062"}
{"pmid": "20992049", "title": "The cytological localization, substrate specificity, and pH optima of phosphatases in the duodenum of the mouse.", "content": "The cytological localization, substrate specificity, and pH optima of phosphatases in the duodenum of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992049"}
{"pmid": "20992063", "title": "A note on eidetic imagery in a case of obsessive neurosis.", "content": "A note on eidetic imagery in a case of obsessive neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992063"}
{"pmid": "20992064", "title": "NOMENCLATURE of psychiatric disorders and reactions.", "content": "NOMENCLATURE of psychiatric disorders and reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992064"}
{"pmid": "20992050", "title": "The quantitative control of cyanide in manometric experimentation.", "content": "The quantitative control of cyanide in manometric experimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992050"}
{"pmid": "20992066", "title": "Social values and psychotherapy.", "content": "Social values and psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992066"}
{"pmid": "20992065", "title": "The study of individual personality by means of the intraindividual correlation.", "content": "The study of individual personality by means of the intraindividual correlation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992065"}
{"pmid": "20992067", "title": "Some roots of prejudice.", "content": "Some roots of prejudice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992067"}
{"pmid": "20992068", "title": "Theory of imagination in Plotinus.", "content": "Theory of imagination in Plotinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992068"}
{"pmid": "20992069", "title": "A Rorschach succession chart.", "content": "A Rorschach succession chart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992069"}
{"pmid": "20992070", "title": "Personality and prejudice.", "content": "Personality and prejudice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992070"}
{"pmid": "20992071", "title": "A cerebral hyperventilation index for electroencephalography.", "content": "A cerebral hyperventilation index for electroencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992071"}
{"pmid": "20992072", "title": "Studies in occupational analysis; originality.", "content": "Studies in occupational analysis; originality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992072"}
{"pmid": "20992073", "title": "On the correlation between a variable and its super-factor.", "content": "On the correlation between a variable and its super-factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992073"}
{"pmid": "20992074", "title": "Functions of clinical psychological service in California juvenile and adult courts.", "content": "Functions of clinical psychological service in California juvenile and adult courts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992074"}
{"pmid": "20992075", "title": "Internal evidence of validity of a rating scale.", "content": "Internal evidence of validity of a rating scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992075"}
{"pmid": "20992076", "title": "Some suggestions concerning the administration and interpretation of the T.A.T.", "content": "Some suggestions concerning the administration and interpretation of the T.A.T.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992076"}
{"pmid": "20992077", "title": "Opinion-attitude methodology.", "content": "Opinion-attitude methodology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992077"}
{"pmid": "20992097", "title": "Puerto Rico's nutritional problem.", "content": "Puerto Rico's nutritional problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992097"}
{"pmid": "20992100", "title": "CO-OPERATIVE investigations relating to the assay of the potency of penicillin carried out for the International Conference.", "content": "CO-OPERATIVE investigations relating to the assay of the potency of penicillin carried out for the International Conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992100"}
{"pmid": "20992099", "title": "RESOLUTIONS adopted at the International Conference on the Standardisation of Penicillin.", "content": "RESOLUTIONS adopted at the International Conference on the Standardisation of Penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992099"}
{"pmid": "20992101", "title": "Report relating to the comparative assay of six samples of penicillin.", "content": "Report relating to the comparative assay of six samples of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992101"}
{"pmid": "20992103", "title": "Report on assay of penicillin.", "content": "Report on assay of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992103"}
{"pmid": "20992102", "title": "Report relating to the assays of penicillin carried out at the Northern Regional Research Laboratory, Peoria, Illinois.", "content": "Report relating to the assays of penicillin carried out at the Northern Regional Research Laboratory, Peoria, Illinois.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992102"}
{"pmid": "20992105", "title": "Report relating to the assays of penicillin carried out at the laboratories of Charles Pfizer & Co., Brooklyn.", "content": "Report relating to the assays of penicillin carried out at the laboratories of Charles Pfizer & Co., Brooklyn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992105"}
{"pmid": "20992104", "title": "Report relating to the assays of penicillin carried out by the United States Food and Drug Administration, Washington, D.C.", "content": "Report relating to the assays of penicillin carried out by the United States Food and Drug Administration, Washington, D.C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992104"}
{"pmid": "20992107", "title": "Report on the comparison of six samples of penicillin supplied by the Department of Biological Standard, Medical Research Council.", "content": "Report on the comparison of six samples of penicillin supplied by the Department of Biological Standard, Medical Research Council.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992107"}
{"pmid": "20992106", "title": "Report submitted relating to the assays of penicillin carried out at the Wellcome Physiological Research Laboratories at Beckenham (Kent) and Belmont (Surrey).", "content": "Report submitted relating to the assays of penicillin carried out at the Wellcome Physiological Research Laboratories at Beckenham (Kent) and Belmont (Surrey).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992106"}
{"pmid": "20992108", "title": "Analysis of the results of the assay of six samples of penicillin carried out at Imperial Chemical (Pharmaceuticals) Laboratory, Blackley, Manchester.", "content": "Analysis of the results of the assay of six samples of penicillin carried out at Imperial Chemical (Pharmaceuticals) Laboratory, Blackley, Manchester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992108"}
{"pmid": "20992121", "title": "FACTS about poison oak.", "content": "FACTS about poison oak.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992121"}
{"pmid": "20992122", "title": "Sewage disposal projects planned in many California cities.", "content": "Sewage disposal projects planned in many California cities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992122"}
{"pmid": "20992123", "title": "Milk; food or poison?", "content": "Milk; food or poison?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992123"}
{"pmid": "20992109", "title": "Report relating to the comparative assay of six samples of penicillin labelled I.C.P., T.R.C., P.B.S., F.D.A. Master Standard, F.D.A. Reference Standard and X.", "content": "Report relating to the comparative assay of six samples of penicillin labelled I.C.P., T.R.C., P.B.S., F.D.A. Master Standard, F.D.A. Reference Standard and X.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992109"}
{"pmid": "20992110", "title": "SUMMARY of the results of the assays of six samples of penicillin salts carried out independently in eight different laboratories.", "content": "SUMMARY of the results of the assays of six samples of penicillin salts carried out independently in eight different laboratories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992110"}
{"pmid": "20992116", "title": "A modification of the cylinder-plate method for the assay of penicillin.", "content": "A modification of the cylinder-plate method for the assay of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992116"}
{"pmid": "20992114", "title": "The assay of penicillin in the days before it was concentrated.", "content": "The assay of penicillin in the days before it was concentrated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992114"}
{"pmid": "20992118", "title": "The assay of penicillin by the dilution method.", "content": "The assay of penicillin by the dilution method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992118"}
{"pmid": "20992129", "title": "Some domestic uses of DDT.", "content": "Some domestic uses of DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992129"}
{"pmid": "20992112", "title": "INTERNATIONAL Penicillin Working Standard.", "content": "INTERNATIONAL Penicillin Working Standard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992112"}
{"pmid": "20992113", "title": "MEMORANDUM on the International Penicillin Standard and the International Penicillin Working Standard.", "content": "MEMORANDUM on the International Penicillin Standard and the International Penicillin Working Standard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992113"}
{"pmid": "20992111", "title": "The International Penicillin Standard (report on its preparation and properties).", "content": "The International Penicillin Standard (report on its preparation and properties).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992111"}
{"pmid": "20992115", "title": "A cylinder-plate method for the assay of penicillin.", "content": "A cylinder-plate method for the assay of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992115"}
{"pmid": "20992130", "title": "The role of vitamins in the nutrition of children.", "content": "The role of vitamins in the nutrition of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992130"}
{"pmid": "20992117", "title": "The assay of penicillin by the cylinder-plate method.", "content": "The assay of penicillin by the cylinder-plate method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992117"}
{"pmid": "20992131", "title": "The control of gastro-intestinal infections, including dysentery.", "content": "The control of gastro-intestinal infections, including dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992131"}
{"pmid": "20992132", "title": "Immunisation against whooping cough; a review.", "content": "Immunisation against whooping cough; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992132"}
{"pmid": "20992119", "title": "The plate droplet method of penicillin assay.", "content": "The plate droplet method of penicillin assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992119"}
{"pmid": "20992133", "title": "A further study of the growth of infants in the first year of life; a comparison between war years as compared with pre-war years in the town of Glossop.", "content": "A further study of the growth of infants in the first year of life; a comparison between war years as compared with pre-war years in the town of Glossop.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992133"}
{"pmid": "20992120", "title": "Note on the broth-dilution method of penicillin assay.", "content": "Note on the broth-dilution method of penicillin assay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992120"}
{"pmid": "20992134", "title": "WHAT to do for flatulence.", "content": "WHAT to do for flatulence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992134"}
{"pmid": "20992139", "title": "TUBERCULOSIS control; past and future.", "content": "TUBERCULOSIS control; past and future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992139"}
{"pmid": "20992140", "title": "A light, compact x-ray generator of high efficiency for mass radiography of the chest.", "content": "A light, compact x-ray generator of high efficiency for mass radiography of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992140"}
{"pmid": "20992141", "title": "An evaluation of a chest x-ray resurvey of an industrial plant.", "content": "An evaluation of a chest x-ray resurvey of an industrial plant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992141"}
{"pmid": "20992142", "title": "Miniature photofluorography of the clothed subject.", "content": "Miniature photofluorography of the clothed subject.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992142"}
{"pmid": "20992143", "title": "Rehabilitation.", "content": "Rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992143"}
{"pmid": "20992144", "title": "The treatment of trypanosomiasis with p-arsenosophenylbutyric acid; results in 319 cases of early Trypanosoma gambiense infections.", "content": "The treatment of trypanosomiasis with p-arsenosophenylbutyric acid; results in 319 cases of early Trypanosoma gambiense infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992144"}
{"pmid": "20992145", "title": "Studies on marihuana and pyrahexyl compound.", "content": "Studies on marihuana and pyrahexyl compound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992145"}
{"pmid": "20992146", "title": "Complement-fixation tests for American trypanosomiasis in Texas.", "content": "Complement-fixation tests for American trypanosomiasis in Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992146"}
{"pmid": "20992147", "title": "Viability of dried Bacterium tularense.", "content": "Viability of dried Bacterium tularense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992147"}
{"pmid": "20992148", "title": "DIAGNOSIS and treatment of tropical diseases.", "content": "DIAGNOSIS and treatment of tropical diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992148"}
{"pmid": "20992152", "title": "The early pneumoencephalographic findings following penetrating wounds of the brain.", "content": "The early pneumoencephalographic findings following penetrating wounds of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992152"}
{"pmid": "20992153", "title": "Scout film of the abdomen.", "content": "Scout film of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992153"}
{"pmid": "20992154", "title": "Emptying of the normal gallbladder with priodax.", "content": "Emptying of the normal gallbladder with priodax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992154"}
{"pmid": "20992155", "title": "Pantopaque myelography; diagnostic errors and review of cases.", "content": "Pantopaque myelography; diagnostic errors and review of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992155"}
{"pmid": "20992156", "title": "Iodinated organic compounds as contrast media for radiographic diagnoses; escape of pantopaque from the intracranial subarachnoid space of dogs.", "content": "Iodinated organic compounds as contrast media for radiographic diagnoses; escape of pantopaque from the intracranial subarachnoid space of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992156"}
{"pmid": "20992157", "title": "Delayed excretory urography; value of the 24 hour urogram.", "content": "Delayed excretory urography; value of the 24 hour urogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992157"}
{"pmid": "20992158", "title": "Pulmonary calcifications; roentgenographic observations in relation to histoplasmin and tuberculin reactions.", "content": "Pulmonary calcifications; roentgenographic observations in relation to histoplasmin and tuberculin reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992158"}
{"pmid": "20992159", "title": "Taenia saginata.", "content": "Taenia saginata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992159"}
{"pmid": "20992160", "title": "Roentgenography of adenoids.", "content": "Roentgenography of adenoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992160"}
{"pmid": "20992161", "title": "Radiation treatment of benign and inflammatory conditions.", "content": "Radiation treatment of benign and inflammatory conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992161"}
{"pmid": "20992162", "title": "Exarticulation of the lower extremities for malignant tumors; hip joint disarticulation (with and without deep iliac dissection) and sacro-iliac disarticulation (hemipelvectomy).", "content": "Exarticulation of the lower extremities for malignant tumors; hip joint disarticulation (with and without deep iliac dissection) and sacro-iliac disarticulation (hemipelvectomy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992162"}
{"pmid": "20992163", "title": "Absorbable gauze in bone surgery.", "content": "Absorbable gauze in bone surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992163"}
{"pmid": "20992164", "title": "Management of late head injuries.", "content": "Management of late head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992164"}
{"pmid": "20992165", "title": "The technic of immediate restoration of vascular continuity after arterial wounds; indications and results.", "content": "The technic of immediate restoration of vascular continuity after arterial wounds; indications and results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992165"}
{"pmid": "20992166", "title": "Reconstruction of the thumb.", "content": "Reconstruction of the thumb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992166"}
{"pmid": "20992167", "title": "Cervical rib: the rôle of the clavicle in occlusion of the subclavian artery.", "content": "Cervical rib: the rôle of the clavicle in occlusion of the subclavian artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992167"}
{"pmid": "20992168", "title": "Resection of the left lobe of the liver for mesenchymoma.", "content": "Resection of the left lobe of the liver for mesenchymoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992168"}
{"pmid": "20992169", "title": "Postoperative atelectasis and pneumonia.", "content": "Postoperative atelectasis and pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992169"}
{"pmid": "20992170", "title": "A two-stage mastopexy in plastic surgery of markedly enlarged breasts.", "content": "A two-stage mastopexy in plastic surgery of markedly enlarged breasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992170"}
{"pmid": "20992171", "title": "A minute granulosa cell tumor, with vaginal bleeding.", "content": "A minute granulosa cell tumor, with vaginal bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992171"}
{"pmid": "20992172", "title": "Streptococcus viridans septicemia from vegetations in femoral arteriovenous aneurysm.", "content": "Streptococcus viridans septicemia from vegetations in femoral arteriovenous aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992172"}
{"pmid": "20992173", "title": "The influence of a special high protein diet on protein regeneration in the surgical patient.", "content": "The influence of a special high protein diet on protein regeneration in the surgical patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992173"}
{"pmid": "20992174", "title": "Gastrojejunocolic fistula following gastrectomy.", "content": "Gastrojejunocolic fistula following gastrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992174"}
{"pmid": "20992175", "title": "Acute intestinal obstruction caused by clamping of the intestine in the umbilical cord clamp.", "content": "Acute intestinal obstruction caused by clamping of the intestine in the umbilical cord clamp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992175"}
{"pmid": "20992176", "title": "A transfascial incision as an approach to the kidney and retroperitoneal space.", "content": "A transfascial incision as an approach to the kidney and retroperitoneal space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992176"}
{"pmid": "20992177", "title": "Ganglion of the common peroneal nerve.", "content": "Ganglion of the common peroneal nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992177"}
{"pmid": "20992178", "title": "Studies on the inguinal region; the anatomy of the inguinal (Hesselbach) triangle.", "content": "Studies on the inguinal region; the anatomy of the inguinal (Hesselbach) triangle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992178"}
{"pmid": "20992185", "title": "The technique of the Syme amputation.", "content": "The technique of the Syme amputation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992185"}
{"pmid": "20992186", "title": "Conservation of short amputation stumps by tendon section.", "content": "Conservation of short amputation stumps by tendon section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992186"}
{"pmid": "20992187", "title": "The overseas treatment of compound fractures of the long bones.", "content": "The overseas treatment of compound fractures of the long bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992187"}
{"pmid": "20992188", "title": "Muscle transplantation for paralysis of the radial nerve.", "content": "Muscle transplantation for paralysis of the radial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992188"}
{"pmid": "20992189", "title": "Bursitis in the region of the fibular collateral ligament.", "content": "Bursitis in the region of the fibular collateral ligament.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992189"}
{"pmid": "20992190", "title": "Air arthrography as an aid to diagnosis of lesions of the menisci of the knee joint.", "content": "Air arthrography as an aid to diagnosis of lesions of the menisci of the knee joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992190"}
{"pmid": "20992191", "title": "Diseases and defects of the musculoskeletal system in air-crew trainees.", "content": "Diseases and defects of the musculoskeletal system in air-crew trainees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992191"}
{"pmid": "20992192", "title": "Acute instability of the ligaments of the knee as a result of injuries to parachutists.", "content": "Acute instability of the ligaments of the knee as a result of injuries to parachutists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992192"}
{"pmid": "20992193", "title": "Disability evaluation for the hand.", "content": "Disability evaluation for the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992193"}
{"pmid": "20992194", "title": "The problem of meniscectomy in the soldier.", "content": "The problem of meniscectomy in the soldier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992194"}
{"pmid": "20992195", "title": "Experiences with the Britain ischiofemoral arthrodesis.", "content": "Experiences with the Britain ischiofemoral arthrodesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992195"}
{"pmid": "20992196", "title": "Sympathetic block of the stellate ganglion; its application; orthopaedic conditions.", "content": "Sympathetic block of the stellate ganglion; its application; orthopaedic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992196"}
{"pmid": "20992197", "title": "The use of iliac bone in bone-grafting and arthrodesis.", "content": "The use of iliac bone in bone-grafting and arthrodesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992197"}
{"pmid": "20992198", "title": "Factors influencing callus formation in open fixation of fractures.", "content": "Factors influencing callus formation in open fixation of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992198"}
{"pmid": "20992199", "title": "Fusion of vertebrae following resection of the intervertebral disc.", "content": "Fusion of vertebrae following resection of the intervertebral disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992199"}
{"pmid": "20992200", "title": "Knee fusion by the use of a three-flanged nail.", "content": "Knee fusion by the use of a three-flanged nail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992200"}
{"pmid": "20992201", "title": "Treatment of congenital dislocation of the hip.", "content": "Treatment of congenital dislocation of the hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992201"}
{"pmid": "20992202", "title": "Compound comminuted fractures involving the elbow joint; treatment by resection of the fragments.", "content": "Compound comminuted fractures involving the elbow joint; treatment by resection of the fragments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992202"}
{"pmid": "20992203", "title": "The treatment of chronic osteomyelitis by the use of muscle transplant or iliac graft.", "content": "The treatment of chronic osteomyelitis by the use of muscle transplant or iliac graft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992203"}
{"pmid": "20992204", "title": "Metatarsal fractures.", "content": "Metatarsal fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992204"}
{"pmid": "20992205", "title": "Arthroplasty of the temporomandibular joint in children with interposition of tantalum foil.", "content": "Arthroplasty of the temporomandibular joint in children with interposition of tantalum foil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992205"}
{"pmid": "20992206", "title": "Gunshot wounds of the major joints.", "content": "Gunshot wounds of the major joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992206"}
{"pmid": "20992207", "title": "Fractures of the head of the radius.", "content": "Fractures of the head of the radius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992207"}
{"pmid": "20992208", "title": "A case resembling hemangiomatosis of the lower extremity.", "content": "A case resembling hemangiomatosis of the lower extremity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992208"}
{"pmid": "20992209", "title": "Eosinophilic granuloma of bone; report of a case involving the clavicle.", "content": "Eosinophilic granuloma of bone; report of a case involving the clavicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992209"}
{"pmid": "20992210", "title": "Deformity of the radius produced by an aneurysm.", "content": "Deformity of the radius produced by an aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992210"}
{"pmid": "20992211", "title": "Calcareous tendinitis of a flexor tendon of the finger.", "content": "Calcareous tendinitis of a flexor tendon of the finger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992211"}
{"pmid": "20992212", "title": "Three instruments designed to facilitate the Bankart operation for recurrent dislocation of the shoulder.", "content": "Three instruments designed to facilitate the Bankart operation for recurrent dislocation of the shoulder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992212"}
{"pmid": "20992213", "title": "Rupture of the pectoralis major.", "content": "Rupture of the pectoralis major.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992213"}
{"pmid": "20992214", "title": "Concealed cysts of the lateral meniscus of the knee.", "content": "Concealed cysts of the lateral meniscus of the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992214"}
{"pmid": "20992215", "title": "Foot exerciser.", "content": "Foot exerciser.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992215"}
{"pmid": "20992233", "title": "Technical considerations in surgical therapy for coarctation of the aorta.", "content": "Technical considerations in surgical therapy for coarctation of the aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992233"}
{"pmid": "20992234", "title": "Arteriovenous fistulas and arterial aneurysms in military personnel.", "content": "Arteriovenous fistulas and arterial aneurysms in military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992234"}
{"pmid": "20992235", "title": "Certain aspects of battle wounds of the thoracic cavity; with special reference to a method of facilitating re-expansion of the lung following late decortication.", "content": "Certain aspects of battle wounds of the thoracic cavity; with special reference to a method of facilitating re-expansion of the lung following late decortication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992235"}
{"pmid": "20992236", "title": "Alterations of the blood following intrathoracic operations; a clinical study.", "content": "Alterations of the blood following intrathoracic operations; a clinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992236"}
{"pmid": "20992237", "title": "Experimental appendical peritonitis; the prognostic significance of certain hematologic factors, especially the prothrombin time.", "content": "Experimental appendical peritonitis; the prognostic significance of certain hematologic factors, especially the prothrombin time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992237"}
{"pmid": "20992238", "title": "Neoplastic biliary obstruction; an improved type of radical pancreaticoduodenectomy for ampullary and pancreatic cancers.", "content": "Neoplastic biliary obstruction; an improved type of radical pancreaticoduodenectomy for ampullary and pancreatic cancers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992238"}
{"pmid": "20992239", "title": "Experiences with the Pauchet technique of colostomy closure.", "content": "Experiences with the Pauchet technique of colostomy closure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992239"}
{"pmid": "20992240", "title": "The treatment of patients with achalasia by esophagogastrostomy.", "content": "The treatment of patients with achalasia by esophagogastrostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992240"}
{"pmid": "20992241", "title": "The treatment of cardiospasm by esophagogastrostomy.", "content": "The treatment of cardiospasm by esophagogastrostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992241"}
{"pmid": "20992242", "title": "Transplantation of toes for fingers.", "content": "Transplantation of toes for fingers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992242"}
{"pmid": "20992243", "title": "Clinical and experimental observations on the use of gelatin sponge or foam.", "content": "Clinical and experimental observations on the use of gelatin sponge or foam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992243"}
{"pmid": "20992244", "title": "Multicentric origin of intraoral carcinoma.", "content": "Multicentric origin of intraoral carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992244"}
{"pmid": "20992246", "title": "Differential spinal block; a preliminary report.", "content": "Differential spinal block; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992246"}
{"pmid": "20992245", "title": "Penicillin-phthalylsulfathiazole antagonism.", "content": "Penicillin-phthalylsulfathiazole antagonism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992245"}
{"pmid": "20992247", "title": "Early rising of patients following surgery.", "content": "Early rising of patients following surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992247"}
{"pmid": "20992248", "title": "The important dividing wall between caudal herniation and prolapse of abdominal or pelvic viscera.", "content": "The important dividing wall between caudal herniation and prolapse of abdominal or pelvic viscera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992248"}
{"pmid": "20992249", "title": "Some observations on the role of protein in pregnancy.", "content": "Some observations on the role of protein in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992249"}
{"pmid": "20992250", "title": "Hysterosalpingography with viscorayopake; preliminary report.", "content": "Hysterosalpingography with viscorayopake; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992250"}
{"pmid": "20992251", "title": "Cancer of the lip in a twelve year old girl.", "content": "Cancer of the lip in a twelve year old girl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992251"}
{"pmid": "20992252", "title": "Heberden's nodes; their relation to other degenerative joint diseases.", "content": "Heberden's nodes; their relation to other degenerative joint diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992252"}
{"pmid": "20992253", "title": "Physical reconditioning of the knee following removal of menisci.", "content": "Physical reconditioning of the knee following removal of menisci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992253"}
{"pmid": "20992254", "title": "Neurosyphilis with a three year observation of the comparative therapeutic effects of inoculation malaria and artificial fever therapy.", "content": "Neurosyphilis with a three year observation of the comparative therapeutic effects of inoculation malaria and artificial fever therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992254"}
{"pmid": "20992255", "title": "Graphic method for rapid estimation of clinical status in poliomyelitis.", "content": "Graphic method for rapid estimation of clinical status in poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992255"}
{"pmid": "20992256", "title": "Peripheral nerve injuries; their diagnosis, prognosis and treatment.", "content": "Peripheral nerve injuries; their diagnosis, prognosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992256"}
{"pmid": "20992257", "title": "Acroparaesthesia.", "content": "Acroparaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992257"}
{"pmid": "20992258", "title": "Pointers in parenteral therapy.", "content": "Pointers in parenteral therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992258"}
{"pmid": "20992259", "title": "The use and abuse of parenteral fluids.", "content": "The use and abuse of parenteral fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992259"}
{"pmid": "20992260", "title": "NORMAL human dried blood plasma; Army-Navy surplus.", "content": "NORMAL human dried blood plasma; Army-Navy surplus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992260"}
{"pmid": "20992261", "title": "The community blood bank; problems and opportunities.", "content": "The community blood bank; problems and opportunities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992261"}
{"pmid": "20992262", "title": "Congenital hemolytic disease and erythroblastosis fetalis; two disease syndromes.", "content": "Congenital hemolytic disease and erythroblastosis fetalis; two disease syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992262"}
{"pmid": "20992263", "title": "Prevention of transfusion reactions due to Rh factors.", "content": "Prevention of transfusion reactions due to Rh factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992263"}
{"pmid": "20992265", "title": "The prescription of physical therapy.", "content": "The prescription of physical therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992265"}
{"pmid": "20992264", "title": "Care of patients with infantile paralysis; correlation in the nursing and physical therapy services.", "content": "Care of patients with infantile paralysis; correlation in the nursing and physical therapy services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992264"}
{"pmid": "20992266", "title": "A history of the American Physiotherapy Association; Maturity, 1939-1946.", "content": "A history of the American Physiotherapy Association; Maturity, 1939-1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992266"}
{"pmid": "20992277", "title": "Medical experiences of the war in the South-East Asia Command.", "content": "Medical experiences of the war in the South-East Asia Command.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992277"}
{"pmid": "20992278", "title": "Venomous marine molluscs of the genus Conus.", "content": "Venomous marine molluscs of the genus Conus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992278"}
{"pmid": "20992279", "title": "An outbreak of Trypanosoma cruzi infection in Indian monkeys.", "content": "An outbreak of Trypanosoma cruzi infection in Indian monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992279"}
{"pmid": "20992280", "title": "Report of a case of multiple idiopathic haemorrhagic sarcoma occurring in a West African native.", "content": "Report of a case of multiple idiopathic haemorrhagic sarcoma occurring in a West African native.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992280"}
{"pmid": "20992267", "title": "Physical medicine at Ohio State University; its relation to the Ohio chapter of the American Physiotherapy Association.", "content": "Physical medicine at Ohio State University; its relation to the Ohio chapter of the American Physiotherapy Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992267"}
{"pmid": "20992281", "title": "Some observations on Salmonella strains in dogs, mice and ticks.", "content": "Some observations on Salmonella strains in dogs, mice and ticks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992281"}
{"pmid": "20992282", "title": "Observations on an antbear (Orycteropus after) in relation to infection with Trypanosoma rhodesiense.", "content": "Observations on an antbear (Orycteropus after) in relation to infection with Trypanosoma rhodesiense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992282"}
{"pmid": "20992268", "title": "SCHOOLS approved for training physical therapists by Council on Medical Education and Hospitals of the American Medical Association.", "content": "SCHOOLS approved for training physical therapists by Council on Medical Education and Hospitals of the American Medical Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992268"}
{"pmid": "20992283", "title": "Cerebral lesions produced in healthy dogs by the intravenous injection of 4: 4'-diamidino stilbene.", "content": "Cerebral lesions produced in healthy dogs by the intravenous injection of 4: 4'-diamidino stilbene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992283"}
{"pmid": "20992284", "title": "Cephalin flocculation test in the detection of pre-icteric infective hepatitis and the prevention of homologous serum jaundice.", "content": "Cephalin flocculation test in the detection of pre-icteric infective hepatitis and the prevention of homologous serum jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992284"}
{"pmid": "20992286", "title": "The treatment of tuberculous arthritis.", "content": "The treatment of tuberculous arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992286"}
{"pmid": "20992285", "title": "Results of BCG immunization in New York City.", "content": "Results of BCG immunization in New York City.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992285"}
{"pmid": "20992287", "title": "Closed intrapleural pneumonolysis and thoracoscopy.", "content": "Closed intrapleural pneumonolysis and thoracoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992287"}
{"pmid": "20992288", "title": "Latent silicosis and tuberculosis.", "content": "Latent silicosis and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992288"}
{"pmid": "20992289", "title": "A mass chest x-ray survey in Philadelphia war industries.", "content": "A mass chest x-ray survey in Philadelphia war industries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992289"}
{"pmid": "20992290", "title": "Tuberculin PPD; a single intermediate dosage used in surveying 8,000 persons.", "content": "Tuberculin PPD; a single intermediate dosage used in surveying 8,000 persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992290"}
{"pmid": "20992291", "title": "Pulmonary lavage; a method for demonstrating tubercle bacilli.", "content": "Pulmonary lavage; a method for demonstrating tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992291"}
{"pmid": "20992292", "title": "Combination egg media for the diagnostic culture of tubercle bacilli.", "content": "Combination egg media for the diagnostic culture of tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992292"}
{"pmid": "20992293", "title": "Tuberculin allergy in patients critically ill with tuberculosis.", "content": "Tuberculin allergy in patients critically ill with tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992293"}
{"pmid": "20992294", "title": "Sulfones in experimental tuberculosis; chemical constitution and chemotherapeutic action.", "content": "Sulfones in experimental tuberculosis; chemical constitution and chemotherapeutic action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992294"}
{"pmid": "20992295", "title": "Chemotherapeutic observations on tubercle bacilli; experiments in vitro and in vivo.", "content": "Chemotherapeutic observations on tubercle bacilli; experiments in vitro and in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992295"}
{"pmid": "20992296", "title": "Pleural transudates; unusual roentgenological configuration associated with congestive failure.", "content": "Pleural transudates; unusual roentgenological configuration associated with congestive failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992296"}
{"pmid": "20992298", "title": "Extraperiosteal pneumothorax in the tropics.", "content": "Extraperiosteal pneumothorax in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992298"}
{"pmid": "20992299", "title": "Experiences with promanide in tuberculosis.", "content": "Experiences with promanide in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992299"}
{"pmid": "20992300", "title": "Transthoracic transpleural ligature of the first part of the left subclavian artery.", "content": "Transthoracic transpleural ligature of the first part of the left subclavian artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992300"}
{"pmid": "20992301", "title": "Tuberculosis, a family disease.", "content": "Tuberculosis, a family disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992301"}
{"pmid": "20992302", "title": "A spot on the lung.", "content": "A spot on the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992302"}
{"pmid": "20992303", "title": "Thickened pleura; cause and significance.", "content": "Thickened pleura; cause and significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992303"}
{"pmid": "20992308", "title": "Basal pulmonary tuberculosis, with special reference to aetiology and treatment.", "content": "Basal pulmonary tuberculosis, with special reference to aetiology and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992308"}
{"pmid": "20992309", "title": "The changing chest clinic.", "content": "The changing chest clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992309"}
{"pmid": "20992310", "title": "An improved stain for fluorescence microscopy.", "content": "An improved stain for fluorescence microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992310"}
{"pmid": "20992311", "title": "Haematological study in pulmonary tuberculosis and the effect upon it of large doses of vitamin C.", "content": "Haematological study in pulmonary tuberculosis and the effect upon it of large doses of vitamin C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992311"}
{"pmid": "20992312", "title": "Artifical anterior pneumomediastinum in the treatment of haemoptysis.", "content": "Artifical anterior pneumomediastinum in the treatment of haemoptysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992312"}
{"pmid": "20992313", "title": "A national scheme for the rehabilitation of the tuberculosis.", "content": "A national scheme for the rehabilitation of the tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992313"}
{"pmid": "20992314", "title": "Study of experimental urinary calculi; persistence of the stone-forming tendency in estrogen-treated male rats and its relation to diet.", "content": "Study of experimental urinary calculi; persistence of the stone-forming tendency in estrogen-treated male rats and its relation to diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992314"}
{"pmid": "20992315", "title": "Horseshoe kidney in pregnancy.", "content": "Horseshoe kidney in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992315"}
{"pmid": "20992316", "title": "Large pyelogenic cyst with crossed renal ectopia.", "content": "Large pyelogenic cyst with crossed renal ectopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992316"}
{"pmid": "20992317", "title": "Pelvic fused kidney with surgical removal of calculi; report of a case.", "content": "Pelvic fused kidney with surgical removal of calculi; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992317"}
{"pmid": "20992318", "title": "Renal ectopia; demonstration of crossed unfused ectopia by fluoroscopy.", "content": "Renal ectopia; demonstration of crossed unfused ectopia by fluoroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992318"}
{"pmid": "20992319", "title": "Supernumerary kidney as a cause of uretero-pelvic obstruction.", "content": "Supernumerary kidney as a cause of uretero-pelvic obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992319"}
{"pmid": "20992320", "title": "Cavernous hemangioma; a renal vascular tumor requiring nephrectomy; an unusual entity.", "content": "Cavernous hemangioma; a renal vascular tumor requiring nephrectomy; an unusual entity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992320"}
{"pmid": "20992321", "title": "Hypernephroma in a polycyctic kidney.", "content": "Hypernephroma in a polycyctic kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992321"}
{"pmid": "20992322", "title": "Report of a case of a mammoth kidney stone.", "content": "Report of a case of a mammoth kidney stone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992322"}
{"pmid": "20992323", "title": "Spontaneous rupture of the urinary bladder.", "content": "Spontaneous rupture of the urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992323"}
{"pmid": "20992324", "title": "Infiltrating carcinoma of the bladder; histologic pattern and degree of cellular differentiation in 97 autopsy cases.", "content": "Infiltrating carcinoma of the bladder; histologic pattern and degree of cellular differentiation in 97 autopsy cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992324"}
{"pmid": "20992325", "title": "Urological complications following operation for imperforate hymen.", "content": "Urological complications following operation for imperforate hymen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992325"}
{"pmid": "20992326", "title": "Regeneration of epithelium of prostatic urethra following resection.", "content": "Regeneration of epithelium of prostatic urethra following resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992326"}
{"pmid": "20992327", "title": "Rupture of the urethra, a new diagnostic sign.", "content": "Rupture of the urethra, a new diagnostic sign.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992327"}
{"pmid": "20992328", "title": "Repair of hypospadias and urethral fistula.", "content": "Repair of hypospadias and urethral fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992328"}
{"pmid": "20992329", "title": "Balanitis xerotica obliterans.", "content": "Balanitis xerotica obliterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992329"}
{"pmid": "20992330", "title": "Non-parasitic chyluria with special reference to traumatic chyluria.", "content": "Non-parasitic chyluria with special reference to traumatic chyluria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992330"}
{"pmid": "20992331", "title": "Experiences with intravenous urography in a general hospital in India.", "content": "Experiences with intravenous urography in a general hospital in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992331"}
{"pmid": "20992332", "title": "The investigation of the spermatogenic function of the testicles in cases of azoospermia.", "content": "The investigation of the spermatogenic function of the testicles in cases of azoospermia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992332"}
{"pmid": "20992333", "title": "Catheter guide for the panendoscope.", "content": "Catheter guide for the panendoscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992333"}
{"pmid": "20992334", "title": "Functional disturbances of the liver in injuries of the genito-urinary system; their influence on the course and outcome of these traumata.", "content": "Functional disturbances of the liver in injuries of the genito-urinary system; their influence on the course and outcome of these traumata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992334"}
{"pmid": "20992335", "title": "Prostatism in women.", "content": "Prostatism in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992335"}
{"pmid": "20992336", "title": "Seminal vesiculitis in the young.", "content": "Seminal vesiculitis in the young.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992336"}
{"pmid": "20992338", "title": "Neurosyphilis.", "content": "Neurosyphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992338"}
{"pmid": "20992337", "title": "Hematuria in prostatism.", "content": "Hematuria in prostatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992337"}
{"pmid": "20992339", "title": "[Mycetoma].", "content": "[Mycetoma].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992339"}
{"pmid": "20992340", "title": "TINEA imbricata.", "content": "TINEA imbricata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992340"}
{"pmid": "20992341", "title": "SPOROTRICHOSIS.", "content": "SPOROTRICHOSIS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992341"}
{"pmid": "20992342", "title": "CHROMOBLASTOMYCOSIS.", "content": "CHROMOBLASTOMYCOSIS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992342"}
{"pmid": "20992343", "title": "INCIDENCE of dermatophytes isolated in México city from the scalp.", "content": "INCIDENCE of dermatophytes isolated in México city from the scalp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992343"}
{"pmid": "20992344", "title": "SYPHILIS in India.", "content": "SYPHILIS in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992344"}
{"pmid": "20992345", "title": "EDUCATION for marriage in a post-war world.", "content": "EDUCATION for marriage in a post-war world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992345"}
{"pmid": "20992346", "title": "Asymptomatic neurosyphilis; a review of the literature.", "content": "Asymptomatic neurosyphilis; a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992346"}
{"pmid": "20992347", "title": "The clinical significance of quantitative serologic tests for syphilis.", "content": "The clinical significance of quantitative serologic tests for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992347"}
{"pmid": "20992348", "title": "Neurosyphilis in younger age groups; an analysis of clinical findings, laboratory studies, and malaria therapy.", "content": "Neurosyphilis in younger age groups; an analysis of clinical findings, laboratory studies, and malaria therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992348"}
{"pmid": "20992349", "title": "Merthiolate (sodium ethyl mercuri thiosalicylate) as a preservative in sera for the serodiagnosis of syphilis.", "content": "Merthiolate (sodium ethyl mercuri thiosalicylate) as a preservative in sera for the serodiagnosis of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992349"}
{"pmid": "20992350", "title": "Semantic confusion and resolution in the concepts of cure in syphilis and of reinfection with syphilis.", "content": "Semantic confusion and resolution in the concepts of cure in syphilis and of reinfection with syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992350"}
{"pmid": "20992351", "title": "Sensitivity of Hemophilus ducreyi to antibiotic and other substances in vitro.", "content": "Sensitivity of Hemophilus ducreyi to antibiotic and other substances in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992351"}
{"pmid": "20992352", "title": "Observations on chancroid therapy with and without sulfathiazole.", "content": "Observations on chancroid therapy with and without sulfathiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992352"}
{"pmid": "20992353", "title": "Sulfathiazole prophylaxis for gonorrhea and chancroid among soldiers in the Caribbean area.", "content": "Sulfathiazole prophylaxis for gonorrhea and chancroid among soldiers in the Caribbean area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992353"}
{"pmid": "20992354", "title": "Techniques accentuating efficiency and speed in gonococcus culture work.", "content": "Techniques accentuating efficiency and speed in gonococcus culture work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992354"}
{"pmid": "20992355", "title": "Comparative study of media for the primary isolation of the gonococcus.", "content": "Comparative study of media for the primary isolation of the gonococcus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992355"}
{"pmid": "20992356", "title": "A microflocculation test for syphilis using cardiolipin antigen; preliminary report.", "content": "A microflocculation test for syphilis using cardiolipin antigen; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992356"}
{"pmid": "20992357", "title": "Masking of early syphilis by penicillin therapy in gonorrhea.", "content": "Masking of early syphilis by penicillin therapy in gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992357"}
{"pmid": "20992358", "title": "The effect of the sodium salts of crystalline penicillin G, crystalline penicillin X, and commercial penicillins on darkfield positive lesions of syphilis.", "content": "The effect of the sodium salts of crystalline penicillin G, crystalline penicillin X, and commercial penicillins on darkfield positive lesions of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992358"}
{"pmid": "20992359", "title": "P. B. O. oven [penicillin in beeswax and oil].", "content": "P. B. O. oven [penicillin in beeswax and oil].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992359"}
{"pmid": "20992360", "title": "Hypersensitiveness in animals; anaphylaxis, atopy, allergy.", "content": "Hypersensitiveness in animals; anaphylaxis, atopy, allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992360"}
{"pmid": "20992361", "title": "CONTROL of trichomoniasis in cattle.", "content": "CONTROL of trichomoniasis in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992361"}
{"pmid": "20992362", "title": "PENICILLIN for veterinary use.", "content": "PENICILLIN for veterinary use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992362"}
{"pmid": "20992363", "title": "OXFORD physiologist fined; notice of appeal in \"causing suffering to cats\" case.", "content": "OXFORD physiologist fined; notice of appeal in \"causing suffering to cats\" case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992363"}
{"pmid": "20992364", "title": "Some clinical observations on Johne's disease of sheep.", "content": "Some clinical observations on Johne's disease of sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992364"}
{"pmid": "20992365", "title": "Some observations on skin disease of the dog.", "content": "Some observations on skin disease of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992365"}
{"pmid": "20992366", "title": "Organo-mercury compounds in veterinary medicine.", "content": "Organo-mercury compounds in veterinary medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992366"}
{"pmid": "20992367", "title": "Hypo. in arsenical poisoning in cattle.", "content": "Hypo. in arsenical poisoning in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992367"}
{"pmid": "20992378", "title": "Microbiological aspects of penicillin; cottonseed meal as a substitute for corn steep liquor in penicillin production.", "content": "Microbiological aspects of penicillin; cottonseed meal as a substitute for corn steep liquor in penicillin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992378"}
{"pmid": "20992379", "title": "Mutation in certain phytopathogenic bacteria induced by acenaphthene.", "content": "Mutation in certain phytopathogenic bacteria induced by acenaphthene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992379"}
{"pmid": "20992387", "title": "A medium for the Nagler plate reactions for the identification of certain clostridia.", "content": "A medium for the Nagler plate reactions for the identification of certain clostridia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992387"}
{"pmid": "20992391", "title": "An improved method for differentiating acid-forming from non-acid-forming bacteria.", "content": "An improved method for differentiating acid-forming from non-acid-forming bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992391"}
{"pmid": "20992394", "title": "The biotin requirements of Neisseria sicca.", "content": "The biotin requirements of Neisseria sicca.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992394"}
{"pmid": "20992397", "title": "The utilization of organic phosphorus by phytoplankton.", "content": "The utilization of organic phosphorus by phytoplankton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992397"}
{"pmid": "20992398", "title": "Note on the technique of making bacteria-free cultures of marine diatoms.", "content": "Note on the technique of making bacteria-free cultures of marine diatoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992398"}
{"pmid": "20992399", "title": "The estimation in sea-water solutions of micro-quantities of mercury in the presence of copper by means of dithizone.", "content": "The estimation in sea-water solutions of micro-quantities of mercury in the presence of copper by means of dithizone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992399"}
{"pmid": "20992400", "title": "The genital ducts of Theodoxus, Lamellaria and Trivia, and a discussion of their evolution in the prosobranchs.", "content": "The genital ducts of Theodoxus, Lamellaria and Trivia, and a discussion of their evolution in the prosobranchs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992400"}
{"pmid": "20992401", "title": "A comparison of the feeding mechanisms of Calma glaucoides and Nebaliopsis typica.", "content": "A comparison of the feeding mechanisms of Calma glaucoides and Nebaliopsis typica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992401"}
{"pmid": "20992402", "title": "On the habits and adaptations of Aloidis (Corbula) gibba.", "content": "On the habits and adaptations of Aloidis (Corbula) gibba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992402"}
{"pmid": "20992403", "title": "Vertebral variation in teleostean fishes; Isospondyli.", "content": "Vertebral variation in teleostean fishes; Isospondyli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992403"}
{"pmid": "20992404", "title": "Permeability and properties of the membranes surrounding the developing egg of Homarus vulgaris.", "content": "Permeability and properties of the membranes surrounding the developing egg of Homarus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992404"}
{"pmid": "20992406", "title": "The heterologous transplantation of mouse tumors induced in vitro.", "content": "The heterologous transplantation of mouse tumors induced in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992406"}
{"pmid": "20992405", "title": "Hypophysectomy in mice with special reference to mammary cancer; a report on the outcome of 351 operations.", "content": "Hypophysectomy in mice with special reference to mammary cancer; a report on the outcome of 351 operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992405"}
{"pmid": "20992396", "title": "Control of culture mites by cigarette paper barriers.", "content": "Control of culture mites by cigarette paper barriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992396"}
{"pmid": "20992407", "title": "The production of a carcinogenic agent in the degradation of cholesterol to progesterone.", "content": "The production of a carcinogenic agent in the degradation of cholesterol to progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992407"}
{"pmid": "20992395", "title": "Chromoblastomycosis; some observations on the types of the disease in South Africa.", "content": "Chromoblastomycosis; some observations on the types of the disease in South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992395"}
{"pmid": "20992408", "title": "Physiological studies on tumor-inhibiting agents; effect on rectal temperatures in normal rabbits of the Serratia marcesens tumor-necrotizing polysaccharide of Shear.", "content": "Physiological studies on tumor-inhibiting agents; effect on rectal temperatures in normal rabbits of the Serratia marcesens tumor-necrotizing polysaccharide of Shear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992408"}
{"pmid": "20992409", "title": "Induction of sarcoma of the liver in the rat with methylcholanthrene and benzpyrene.", "content": "Induction of sarcoma of the liver in the rat with methylcholanthrene and benzpyrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992409"}
{"pmid": "20992410", "title": "Nucleic acids in human tumors.", "content": "Nucleic acids in human tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992410"}
{"pmid": "20992411", "title": "Multiple malignant growths.", "content": "Multiple malignant growths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992411"}
{"pmid": "20992412", "title": "WHAT is the cancer situation today?", "content": "WHAT is the cancer situation today?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992412"}
{"pmid": "20992413", "title": "EXAMINATION of the patient for cancer.", "content": "EXAMINATION of the patient for cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992413"}
{"pmid": "20992414", "title": "EARLY diagnosis of cancer in the digestive tract.", "content": "EARLY diagnosis of cancer in the digestive tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992414"}
{"pmid": "20992415", "title": "EARLY diagnosis of cancer of the breast and genital tract.", "content": "EARLY diagnosis of cancer of the breast and genital tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992415"}
{"pmid": "20992417", "title": "EARLY diagnosis of cancer of the urogenital tract.", "content": "EARLY diagnosis of cancer of the urogenital tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992417"}
{"pmid": "20992416", "title": "EARLY diagnosis of cancer of the tongue, parotids, larynx, thyroid, and bronchopulmonary tract.", "content": "EARLY diagnosis of cancer of the tongue, parotids, larynx, thyroid, and bronchopulmonary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992416"}
{"pmid": "20992418", "title": "EARLY diagnosis of cancer of the bone.", "content": "EARLY diagnosis of cancer of the bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992418"}
{"pmid": "20992419", "title": "ROENTGENOLOGY in the early diagnosis of cancer.", "content": "ROENTGENOLOGY in the early diagnosis of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992419"}
{"pmid": "20992428", "title": "Cardiac aspects in the care of veterans.", "content": "Cardiac aspects in the care of veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992428"}
{"pmid": "20992429", "title": "Ferritin; its properties and significance for iron metabolism.", "content": "Ferritin; its properties and significance for iron metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992429"}
{"pmid": "20992430", "title": "The chemistry of the diaryl ethers.", "content": "The chemistry of the diaryl ethers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992430"}
{"pmid": "20992431", "title": "Aromatic cyclodehydration.", "content": "Aromatic cyclodehydration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992431"}
{"pmid": "20992432", "title": "The isolation and synthesis of the naturally occurring alpha-amino acids.", "content": "The isolation and synthesis of the naturally occurring alpha-amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992432"}
{"pmid": "20992441", "title": "A discussion on units and standards.", "content": "A discussion on units and standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992441"}
{"pmid": "20992443", "title": "The standards of length in wavelengths of light.", "content": "The standards of length in wavelengths of light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992443"}
{"pmid": "20992442", "title": "The standards of length.", "content": "The standards of length.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992442"}
{"pmid": "20992445", "title": "The temperature scale.", "content": "The temperature scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992445"}
{"pmid": "20992446", "title": "Electrical standards.", "content": "Electrical standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992446"}
{"pmid": "20992444", "title": "The standards of mass.", "content": "The standards of mass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992444"}
{"pmid": "20992447", "title": "The acceleration due to gravity.", "content": "The acceleration due to gravity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992447"}
{"pmid": "20992448", "title": "The barometric standard.", "content": "The barometric standard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992448"}
{"pmid": "20992449", "title": "The measurement of volume.", "content": "The measurement of volume.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992449"}
{"pmid": "20992450", "title": "PHOTOMETRIC units and standards.", "content": "PHOTOMETRIC units and standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992450"}
{"pmid": "20992452", "title": "The emission of light from spark discharges.", "content": "The emission of light from spark discharges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992452"}
{"pmid": "20992451", "title": "Acoustical standards of measurement.", "content": "Acoustical standards of measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992451"}
{"pmid": "20992453", "title": "Further interferometric studies with mica; new multiple-beam fringes and their application.", "content": "Further interferometric studies with mica; new multiple-beam fringes and their application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992453"}
{"pmid": "20992454", "title": "General surgical principles related to the operation for the removal of the impacted lower third molar.", "content": "General surgical principles related to the operation for the removal of the impacted lower third molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992454"}
{"pmid": "20992455", "title": "Retained tooth roots.", "content": "Retained tooth roots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992455"}
{"pmid": "20992456", "title": "The choice of anesthetic method for oral surgery.", "content": "The choice of anesthetic method for oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992456"}
{"pmid": "20992457", "title": "The principles of full denture construction.", "content": "The principles of full denture construction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992457"}
{"pmid": "20992458", "title": "Solitary bone cysts in the mandible.", "content": "Solitary bone cysts in the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992458"}
{"pmid": "20992459", "title": "Oral penicillin; indications.", "content": "Oral penicillin; indications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992459"}
{"pmid": "20992460", "title": "The nature of adamantinoma.", "content": "The nature of adamantinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992460"}
{"pmid": "20992461", "title": "What has pedodontia for you?", "content": "What has pedodontia for you?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992461"}
{"pmid": "20992462", "title": "A dental officer visits a dental section of a Japanese hospital.", "content": "A dental officer visits a dental section of a Japanese hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992462"}
{"pmid": "20992463", "title": "Some examples of crown and bridgework seen in the mouths of Japanese prisoners.", "content": "Some examples of crown and bridgework seen in the mouths of Japanese prisoners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992463"}
{"pmid": "20992464", "title": "Dentistry in khaki.", "content": "Dentistry in khaki.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992464"}
{"pmid": "20992465", "title": "Pocket therapy in periodontal diseases.", "content": "Pocket therapy in periodontal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992465"}
{"pmid": "20992466", "title": "The basic medical sciences in graduate training in oral surgery.", "content": "The basic medical sciences in graduate training in oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992466"}
{"pmid": "20992467", "title": "REQUIREMENTS for the approval of hospital internships and residencies.", "content": "REQUIREMENTS for the approval of hospital internships and residencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992467"}
{"pmid": "20992468", "title": "Mixed tumors of the lip.", "content": "Mixed tumors of the lip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992468"}
{"pmid": "20992469", "title": "Bilateral osteotomy of the mandibular rami for correction of prognathism in an edentulous mouth; report of case.", "content": "Bilateral osteotomy of the mandibular rami for correction of prognathism in an edentulous mouth; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992469"}
{"pmid": "20992470", "title": "Periodontal cyst; report of case.", "content": "Periodontal cyst; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992470"}
{"pmid": "20992471", "title": "Xanthomatosis (Schuller-Christian's disease); report of dental findings in one case.", "content": "Xanthomatosis (Schuller-Christian's disease); report of dental findings in one case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992471"}
{"pmid": "20992472", "title": "Peripheral giant-cell tumor (giant-cell epulis); report of case.", "content": "Peripheral giant-cell tumor (giant-cell epulis); report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992472"}
{"pmid": "20992473", "title": "Dentigerous cyst; report of case.", "content": "Dentigerous cyst; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992473"}
{"pmid": "20992474", "title": "Impacted lower third and fourth molars; report of a case.", "content": "Impacted lower third and fourth molars; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992474"}
{"pmid": "20992475", "title": "Median anterior maxillary cyst; report of case.", "content": "Median anterior maxillary cyst; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992475"}
{"pmid": "20992476", "title": "Central giant-cell tumor; report of case.", "content": "Central giant-cell tumor; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992476"}
{"pmid": "20992477", "title": "Fundamentals and technic of surgical periodontal packing.", "content": "Fundamentals and technic of surgical periodontal packing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992477"}
{"pmid": "20992478", "title": "Cystic adamantinoma (ameloblastoma); report of case.", "content": "Cystic adamantinoma (ameloblastoma); report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992478"}
{"pmid": "20992479", "title": "Fracture of the mandible; report of case.", "content": "Fracture of the mandible; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992479"}
{"pmid": "20992480", "title": "Cholesteatoma of the maxilla; report of case.", "content": "Cholesteatoma of the maxilla; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992480"}
{"pmid": "20992481", "title": "Arthroplasty with fatal outcome; report of case.", "content": "Arthroplasty with fatal outcome; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992481"}
{"pmid": "20992482", "title": "Mandibular fracture with a tooth in the fracture line; report of a case.", "content": "Mandibular fracture with a tooth in the fracture line; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992482"}
{"pmid": "20992483", "title": "Impacted right and left mandibular third molars with inferior dental nerves passing through the mesial roots; report of case.", "content": "Impacted right and left mandibular third molars with inferior dental nerves passing through the mesial roots; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992483"}
{"pmid": "20992484", "title": "Infected compound composite odontoma; report of case.", "content": "Infected compound composite odontoma; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992484"}
{"pmid": "20992485", "title": "A technic for the removal of salivary calculi from Wharton's duct.", "content": "A technic for the removal of salivary calculi from Wharton's duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992485"}
{"pmid": "20992486", "title": "The present status of oral surgery as a specialty.", "content": "The present status of oral surgery as a specialty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992486"}
{"pmid": "20992487", "title": "AMERICAN Academy of Oral Pathology.", "content": "AMERICAN Academy of Oral Pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992487"}
{"pmid": "20992488", "title": "Ankylosis and trismus resulting from war wounds involving the coronoid region of the mandible; report of three cases.", "content": "Ankylosis and trismus resulting from war wounds involving the coronoid region of the mandible; report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992488"}
{"pmid": "20992494", "title": "Gold inlays and crown and bridge prosthesis.", "content": "Gold inlays and crown and bridge prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992494"}
{"pmid": "20992500", "title": "Latent syphilis; study of 169 cases observed 10 years or more.", "content": "Latent syphilis; study of 169 cases observed 10 years or more.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992500"}
{"pmid": "20992501", "title": "Penicillin in dermatology; a study of 174 cases.", "content": "Penicillin in dermatology; a study of 174 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992501"}
{"pmid": "20992502", "title": "Preservation of virulence of Treponema pallidum; some additional laboratory methods.", "content": "Preservation of virulence of Treponema pallidum; some additional laboratory methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992502"}
{"pmid": "20992503", "title": "Temporary unilateral loss of vision associated with ioderma.", "content": "Temporary unilateral loss of vision associated with ioderma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992503"}
{"pmid": "20992504", "title": "Psychosomatic aspects of lupus erythematosus.", "content": "Psychosomatic aspects of lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992504"}
{"pmid": "20992505", "title": "Delusion of parasitosis (acarophobia).", "content": "Delusion of parasitosis (acarophobia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992505"}
{"pmid": "20992506", "title": "Erysipeloid; successful treatment with penicillin; report of a case.", "content": "Erysipeloid; successful treatment with penicillin; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992506"}
{"pmid": "20992507", "title": "Leukonychia striata semilunaris.", "content": "Leukonychia striata semilunaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992507"}
{"pmid": "20992508", "title": "Rational pharmaceutic treatment of diseases of the skin.", "content": "Rational pharmaceutic treatment of diseases of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992508"}
{"pmid": "20992509", "title": "Cutaneous iridiform gangrene due to a chemical agent.", "content": "Cutaneous iridiform gangrene due to a chemical agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992509"}
{"pmid": "20992510", "title": "An unusual source of dermatitis due to nail polish.", "content": "An unusual source of dermatitis due to nail polish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992510"}
{"pmid": "20992511", "title": "Treatment of condyloma acuminatum with resin of podophyllum.", "content": "Treatment of condyloma acuminatum with resin of podophyllum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992511"}
{"pmid": "20992512", "title": "A modified calamine liniment.", "content": "A modified calamine liniment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992512"}
{"pmid": "20992513", "title": "Is penicillin a photosensitizing agent?", "content": "Is penicillin a photosensitizing agent?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992513"}
{"pmid": "20992514", "title": "Passive immunization in pemphigus vulgaris.", "content": "Passive immunization in pemphigus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992514"}
{"pmid": "20992515", "title": "Keratosis follicularis.", "content": "Keratosis follicularis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992515"}
{"pmid": "20992516", "title": "Lupus erythematosus and dermatitis venenata.", "content": "Lupus erythematosus and dermatitis venenata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992516"}
{"pmid": "20992517", "title": "Acne vulgaris.", "content": "Acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992517"}
{"pmid": "20992518", "title": "Neurotic excoriations; Raynaud's disease.", "content": "Neurotic excoriations; Raynaud's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992518"}
{"pmid": "20992519", "title": "A case for diagnosis (dermatitis factitia? gumma of the right great toe and chronic osteomyelitis of the right first metatarsal and left tibia? epithelial sinus?).", "content": "A case for diagnosis (dermatitis factitia? gumma of the right great toe and chronic osteomyelitis of the right first metatarsal and left tibia? epithelial sinus?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992519"}
{"pmid": "20992520", "title": "Keratitis, syphilitic, congenital.", "content": "Keratitis, syphilitic, congenital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992520"}
{"pmid": "20992521", "title": "A case for diagnosis (syphilitic ulcer?).", "content": "A case for diagnosis (syphilitic ulcer?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992521"}
{"pmid": "20992522", "title": "A case for diagnosis (neurofibromatosis with sarcomatous changes?).", "content": "A case for diagnosis (neurofibromatosis with sarcomatous changes?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992522"}
{"pmid": "20992523", "title": "A case for diagnosis (moniliasis of groins and submammary folds?).", "content": "A case for diagnosis (moniliasis of groins and submammary folds?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992523"}
{"pmid": "20992524", "title": "Dermatitis medicamentosa (due to sulfadiazine).", "content": "Dermatitis medicamentosa (due to sulfadiazine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992524"}
{"pmid": "20992525", "title": "Dermatitis medicamentosa (due to arsenic).", "content": "Dermatitis medicamentosa (due to arsenic).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992525"}
{"pmid": "20992526", "title": "Raynaud's disease.", "content": "Raynaud's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992526"}
{"pmid": "20992527", "title": "Excessive oiliness of the skin and paralysis agitans.", "content": "Excessive oiliness of the skin and paralysis agitans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992527"}
{"pmid": "20992528", "title": "A case for diagnosis (lymphoblastoma?).", "content": "A case for diagnosis (lymphoblastoma?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992528"}
{"pmid": "20992529", "title": "A case for diagnosis (lymphoblastoma?).", "content": "A case for diagnosis (lymphoblastoma?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992529"}
{"pmid": "20992530", "title": "Acrodermatitis atrophicans chronica and squamous cell epithelioma.", "content": "Acrodermatitis atrophicans chronica and squamous cell epithelioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992530"}
{"pmid": "20992531", "title": "Dermatitis venenata due to hair dye.", "content": "Dermatitis venenata due to hair dye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992531"}
{"pmid": "20992532", "title": "Hypertrophic lichen planus.", "content": "Hypertrophic lichen planus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992532"}
{"pmid": "20992533", "title": "A case for diagnosis (purpura?).", "content": "A case for diagnosis (purpura?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992533"}
{"pmid": "20992534", "title": "A case for diagnosis (melanoma of skin?).", "content": "A case for diagnosis (melanoma of skin?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992534"}
{"pmid": "20992535", "title": "Necrobiosis lipoidica diabeticorum without diabetes.", "content": "Necrobiosis lipoidica diabeticorum without diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992535"}
{"pmid": "20992536", "title": "Xanthelasma.", "content": "Xanthelasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992536"}
{"pmid": "20992537", "title": "Acanthosis nigricans (juvenile).", "content": "Acanthosis nigricans (juvenile).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992537"}
{"pmid": "20992538", "title": "Sycosis vulgaris treated with penicillin ointment.", "content": "Sycosis vulgaris treated with penicillin ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992538"}
{"pmid": "20992539", "title": "Pityriasis lichenoides et varioliformis acuta.", "content": "Pityriasis lichenoides et varioliformis acuta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992539"}
{"pmid": "20992540", "title": "Localized scleroderma and calcinosis cutis.", "content": "Localized scleroderma and calcinosis cutis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992540"}
{"pmid": "20992541", "title": "A case for diagnosis (pseudoxanthoma elasticum (?) in an albino Negro woman).", "content": "A case for diagnosis (pseudoxanthoma elasticum (?) in an albino Negro woman).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992541"}
{"pmid": "20992542", "title": "A case for diagnosis (lupus erythematosus; tuberculosis?).", "content": "A case for diagnosis (lupus erythematosus; tuberculosis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992542"}
{"pmid": "20992543", "title": "Edema of eyelids and cheeks on exposure to wind and cold; physical allergy.", "content": "Edema of eyelids and cheeks on exposure to wind and cold; physical allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992543"}
{"pmid": "20992544", "title": "Folic acid takes its place in the vitamin B series.", "content": "Folic acid takes its place in the vitamin B series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992544"}
{"pmid": "20992545", "title": "Are prepackaged frozen meats ready for the retailer?", "content": "Are prepackaged frozen meats ready for the retailer?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992545"}
{"pmid": "20992546", "title": "Rapid method for determining fat content of dried eggs.", "content": "Rapid method for determining fat content of dried eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992546"}
{"pmid": "20992547", "title": "Future of frozen foods depends on proper packaging.", "content": "Future of frozen foods depends on proper packaging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992547"}
{"pmid": "20992548", "title": "Enzyme activity; index of quality in frozen vegetables.", "content": "Enzyme activity; index of quality in frozen vegetables.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992548"}
{"pmid": "20992549", "title": "Nutritional problems in the food industries.", "content": "Nutritional problems in the food industries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992549"}
{"pmid": "20992550", "title": "PRESENT knowledge of the minerals in nutrition; Pt. 1.", "content": "PRESENT knowledge of the minerals in nutrition; Pt. 1.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992550"}
{"pmid": "20992551", "title": "FOLIC ACID.", "content": "FOLIC ACID.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992551"}
{"pmid": "20992552", "title": "FORMATION of thyroxine in iodinated casein.", "content": "FORMATION of thyroxine in iodinated casein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992552"}
{"pmid": "20992553", "title": "GALACTOSEMIA associated with cataracts in an infant.", "content": "GALACTOSEMIA associated with cataracts in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992553"}
{"pmid": "20992554", "title": "FATTY acid oxidation.", "content": "FATTY acid oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992554"}
{"pmid": "20992555", "title": "BRITISH anti-lewisite (BAL).", "content": "BRITISH anti-lewisite (BAL).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992555"}
{"pmid": "20992556", "title": "VITAMIN B-complex in the colostrum and milk of ruminants.", "content": "VITAMIN B-complex in the colostrum and milk of ruminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992556"}
{"pmid": "20992557", "title": "THYROXINE synthesis by thyroid tissue.", "content": "THYROXINE synthesis by thyroid tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992557"}
{"pmid": "20992558", "title": "INTERMITTENT fasting and longevity in rats.", "content": "INTERMITTENT fasting and longevity in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992558"}
{"pmid": "20992559", "title": "ENVIRONMENT and heredity in relation to vitamin contents of plants.", "content": "ENVIRONMENT and heredity in relation to vitamin contents of plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992559"}
{"pmid": "20992560", "title": "Present trends in mucous colitis.", "content": "Present trends in mucous colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992560"}
{"pmid": "20992561", "title": "An outline for the treatment of peptic ulcer.", "content": "An outline for the treatment of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992561"}
{"pmid": "20992563", "title": "Benign ulcer of the caecum.", "content": "Benign ulcer of the caecum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992563"}
{"pmid": "20992562", "title": "Studies of the effects of high lipid diets on intestinal elimination; unsaturated glycerides with special reference to triolein.", "content": "Studies of the effects of high lipid diets on intestinal elimination; unsaturated glycerides with special reference to triolein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992562"}
{"pmid": "20992564", "title": "The correlation of intestinal protozoa and enteric microorganisms of known and doubtful pathogenicity.", "content": "The correlation of intestinal protozoa and enteric microorganisms of known and doubtful pathogenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992564"}
{"pmid": "20992565", "title": "Jejunal cancer; a case report.", "content": "Jejunal cancer; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992565"}
{"pmid": "20992566", "title": "Medical management of pyloric obstruction resulting from peptic ulcer.", "content": "Medical management of pyloric obstruction resulting from peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992566"}
{"pmid": "20992572", "title": "Adolescent sterility in the human female.", "content": "Adolescent sterility in the human female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992572"}
{"pmid": "20992573", "title": "The deficit in the birthrate of college graduates.", "content": "The deficit in the birthrate of college graduates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992573"}
{"pmid": "20992574", "title": "The functions of a medical advisory board in a planned parenthood organization.", "content": "The functions of a medical advisory board in a planned parenthood organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992574"}
{"pmid": "20992575", "title": "The role of a medical consultant in a state planned parenthood league.", "content": "The role of a medical consultant in a state planned parenthood league.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992575"}
{"pmid": "20992576", "title": "PLANNED parenthood services in the United States.", "content": "PLANNED parenthood services in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992576"}
{"pmid": "20992577", "title": "A new method of treatment for vaginitis and cervicitis.", "content": "A new method of treatment for vaginitis and cervicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992577"}
{"pmid": "20992578", "title": "A test for determining the time of ovulation and conception in women.", "content": "A test for determining the time of ovulation and conception in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992578"}
{"pmid": "20992579", "title": "Delayed ovulation, a significant factor in the variability of the menstrual cycle.", "content": "Delayed ovulation, a significant factor in the variability of the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992579"}
{"pmid": "20992580", "title": "Semen analysis in 1,500 cases of sterile marriage.", "content": "Semen analysis in 1,500 cases of sterile marriage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992580"}
{"pmid": "20992581", "title": "Weight control, diet, and fluid balance in pregnancy.", "content": "Weight control, diet, and fluid balance in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992581"}
{"pmid": "20992582", "title": "Therapeutic abortion in a general hospital.", "content": "Therapeutic abortion in a general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992582"}
{"pmid": "20992583", "title": "Interpretation of the pathogenesis of pelvic infection as determined by cornual resection.", "content": "Interpretation of the pathogenesis of pelvic infection as determined by cornual resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992583"}
{"pmid": "20992584", "title": "The clinical diagnosis of varying degrees of uterine contraction rings.", "content": "The clinical diagnosis of varying degrees of uterine contraction rings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992584"}
{"pmid": "20992585", "title": "The persistence of the gonococcus in the female adnexa.", "content": "The persistence of the gonococcus in the female adnexa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992585"}
{"pmid": "20992586", "title": "In trapartum fever: a preliminary study.", "content": "In trapartum fever: a preliminary study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992586"}
{"pmid": "20992587", "title": "Continuous spinal analgesia in cesarean section; its advantages, technique, and an analysis of three hundred cases.", "content": "Continuous spinal analgesia in cesarean section; its advantages, technique, and an analysis of three hundred cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992587"}
{"pmid": "20992588", "title": "The Rh factor in obstetrics.", "content": "The Rh factor in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992588"}
{"pmid": "20992589", "title": "The Kielland forceps for use in the occipitoposterior and occipitotransverse positions.", "content": "The Kielland forceps for use in the occipitoposterior and occipitotransverse positions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992589"}
{"pmid": "20992590", "title": "The origin of adrenal-like tumor of the ovary (hypernephroma of ovary, adrenal tumor of ovary, masculinovoblastoma, luteoma, luteinoma).", "content": "The origin of adrenal-like tumor of the ovary (hypernephroma of ovary, adrenal tumor of ovary, masculinovoblastoma, luteoma, luteinoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992590"}
{"pmid": "20992591", "title": "Arrhenoblastoma of the ovary; report of two cases.", "content": "Arrhenoblastoma of the ovary; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992591"}
{"pmid": "20992592", "title": "Another case of arrhenoblastoma.", "content": "Another case of arrhenoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992592"}
{"pmid": "20992593", "title": "Large ovarian cyst; report of a case.", "content": "Large ovarian cyst; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992593"}
{"pmid": "20992594", "title": "An unusual case of rupture of the uterus with massive hemorrhage.", "content": "An unusual case of rupture of the uterus with massive hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992594"}
{"pmid": "20992595", "title": "Bilateral concomitant fibroma and serous cystadenoma of the ovary.", "content": "Bilateral concomitant fibroma and serous cystadenoma of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992595"}
{"pmid": "20992596", "title": "Acute suppurative parotitis complicating pregnancy at term.", "content": "Acute suppurative parotitis complicating pregnancy at term.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992596"}
{"pmid": "20992597", "title": "Enterouterine fistula; with a review of the literature and report of an unusual case.", "content": "Enterouterine fistula; with a review of the literature and report of an unusual case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992597"}
{"pmid": "20992598", "title": "Abdominal wall fibroma (urachal?) simulating ovarian cystoma.", "content": "Abdominal wall fibroma (urachal?) simulating ovarian cystoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992598"}
{"pmid": "20992599", "title": "Primary lipoma of uterus.", "content": "Primary lipoma of uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992599"}
{"pmid": "20992600", "title": "Abdominal pregnancy with placenta attached to the spleen.", "content": "Abdominal pregnancy with placenta attached to the spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992600"}
{"pmid": "20992601", "title": "Infrequency of carcinoma of the uterine cervix among Jewish women.", "content": "Infrequency of carcinoma of the uterine cervix among Jewish women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992601"}
{"pmid": "20992602", "title": "Multiple pregnancy with early abortion of one fetus.", "content": "Multiple pregnancy with early abortion of one fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992602"}
{"pmid": "20992603", "title": "Vaginal hysterectomy (with the review of author's 203 cases).", "content": "Vaginal hysterectomy (with the review of author's 203 cases).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992603"}
{"pmid": "20992605", "title": "The future of paediatrics.", "content": "The future of paediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992605"}
{"pmid": "20992604", "title": "The importance of antenatal exercises.", "content": "The importance of antenatal exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992604"}
{"pmid": "20992606", "title": "The future of paediatrics.", "content": "The future of paediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992606"}
{"pmid": "20992607", "title": "Infant welfare in Australia.", "content": "Infant welfare in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992607"}
{"pmid": "20992608", "title": "A midwife surveys the Health Service Bill.", "content": "A midwife surveys the Health Service Bill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992608"}
{"pmid": "20992623", "title": "Natural diseases and rational treatment in primitive medicine.", "content": "Natural diseases and rational treatment in primitive medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992623"}
{"pmid": "20992624", "title": "Bibiography of the history of medicine of the United States and Canada, 1945.", "content": "Bibiography of the history of medicine of the United States and Canada, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992624"}
{"pmid": "20992625", "title": "The importance of making provings.", "content": "The importance of making provings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992625"}
{"pmid": "20992626", "title": "The food value of the potato.", "content": "The food value of the potato.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992626"}
{"pmid": "20992627", "title": "Eye diseases in the East.", "content": "Eye diseases in the East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992627"}
{"pmid": "20992628", "title": "Therapeutics throughout the ages.", "content": "Therapeutics throughout the ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992628"}
{"pmid": "20992629", "title": "DISCIPLINE in the nursing service.", "content": "DISCIPLINE in the nursing service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992629"}
{"pmid": "20992630", "title": "Persistence can curb noise nuisance.", "content": "Persistence can curb noise nuisance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992630"}
{"pmid": "20992632", "title": "FOWLER position.", "content": "FOWLER position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992632"}
{"pmid": "20992631", "title": "VOLUNTARY social agency and medico-social work.", "content": "VOLUNTARY social agency and medico-social work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992631"}
{"pmid": "20992633", "title": "The care of the chronically ill patient.", "content": "The care of the chronically ill patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992633"}
{"pmid": "20992634", "title": "LOW cost temporary building for tuberculosis in Vancouver.", "content": "LOW cost temporary building for tuberculosis in Vancouver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992634"}
{"pmid": "20992635", "title": "Changes inevitable in nursing system.", "content": "Changes inevitable in nursing system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992635"}
{"pmid": "20992636", "title": "Environmental sanitation, as applied to hospitals.", "content": "Environmental sanitation, as applied to hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992636"}
{"pmid": "20992637", "title": "AIDS for the armless.", "content": "AIDS for the armless.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992637"}
{"pmid": "20992638", "title": "Nursing through the ages.", "content": "Nursing through the ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992638"}
{"pmid": "20992639", "title": "Re-orientation of the Poor Law, 1930-1945; effects of changing legislation.", "content": "Re-orientation of the Poor Law, 1930-1945; effects of changing legislation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992639"}
{"pmid": "20992640", "title": "Fires and explosions in operating theatres; some reasons and remedies.", "content": "Fires and explosions in operating theatres; some reasons and remedies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992640"}
{"pmid": "20992641", "title": "BROMPTON Hospital for consumption and diseases of the chest.", "content": "BROMPTON Hospital for consumption and diseases of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992641"}
{"pmid": "20992642", "title": "Why not discard medical records after 25 years?", "content": "Why not discard medical records after 25 years?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992642"}
{"pmid": "20992643", "title": "Tuberculosis control; the essentials.", "content": "Tuberculosis control; the essentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992643"}
{"pmid": "20992644", "title": "Tuberculosis control; the finances.", "content": "Tuberculosis control; the finances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992644"}
{"pmid": "20992645", "title": "Tuberculosis control; the statistics.", "content": "Tuberculosis control; the statistics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992645"}
{"pmid": "20992646", "title": "Tuberculosis control; the records.", "content": "Tuberculosis control; the records.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992646"}
{"pmid": "20992647", "title": "Tuberculosis control; the mental patient.", "content": "Tuberculosis control; the mental patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992647"}
{"pmid": "20992648", "title": "Tuberculosis control; one county's report.", "content": "Tuberculosis control; one county's report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992648"}
{"pmid": "20992650", "title": "VETERANS' program.", "content": "VETERANS' program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992650"}
{"pmid": "20992649", "title": "Tuberculosis control; a simple routine.", "content": "Tuberculosis control; a simple routine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992649"}
{"pmid": "20992651", "title": "Practical nurses; the vital part they play.", "content": "Practical nurses; the vital part they play.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992651"}
{"pmid": "20992652", "title": "Planning for efficiency as the mental hospital grows.", "content": "Planning for efficiency as the mental hospital grows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992652"}
{"pmid": "20992653", "title": "Designed for premature living.", "content": "Designed for premature living.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992653"}
{"pmid": "20992654", "title": "Color and psychotherapy.", "content": "Color and psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992654"}
{"pmid": "20992655", "title": "The case of dietitian versus hospital field.", "content": "The case of dietitian versus hospital field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992655"}
{"pmid": "20992656", "title": "Simplified reports save labor in the laboratory.", "content": "Simplified reports save labor in the laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992656"}
{"pmid": "20992657", "title": "The production of typhoid antibodies in rabbits with the use of living typhoid organisms adsorbed on aluminum cream.", "content": "The production of typhoid antibodies in rabbits with the use of living typhoid organisms adsorbed on aluminum cream.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992657"}
{"pmid": "20992658", "title": "The action of antimony and some other bacteriostatic substances on Donovania granulomatis isolated in the chick embryo.", "content": "The action of antimony and some other bacteriostatic substances on Donovania granulomatis isolated in the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992658"}
{"pmid": "20992659", "title": "Studies of the complement-fixation reaction in virus systems; activities of vaccinia virus antigens and antisera.", "content": "Studies of the complement-fixation reaction in virus systems; activities of vaccinia virus antigens and antisera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992659"}
{"pmid": "20992660", "title": "The immunochemistry of toxins and toxoids; the solubility and precipitation of tetanal toxin and toxoid in methanol-water mixtures under controlled conditions of pH, ionic strength and temperature.", "content": "The immunochemistry of toxins and toxoids; the solubility and precipitation of tetanal toxin and toxoid in methanol-water mixtures under controlled conditions of pH, ionic strength and temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992660"}
{"pmid": "20992661", "title": "Studies on the chemotherapy of viruses in the psittacosis-lymphogranuloma venereum group; effect of certain chemotherapeutic agents on psittacosis virus (6BC strain) infections in mice.", "content": "Studies on the chemotherapy of viruses in the psittacosis-lymphogranuloma venereum group; effect of certain chemotherapeutic agents on psittacosis virus (6BC strain) infections in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992661"}
{"pmid": "20992662", "title": "Studies on lymphogranuloma venereum complement-fixing antigens; enhancement by phenol or boiling.", "content": "Studies on lymphogranuloma venereum complement-fixing antigens; enhancement by phenol or boiling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992662"}
{"pmid": "20992663", "title": "Studies on lymphogranuloma venereum complement-fixing antigens; serological studies with boiled phenolized antigens.", "content": "Studies on lymphogranuloma venereum complement-fixing antigens; serological studies with boiled phenolized antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992663"}
{"pmid": "20992664", "title": "The recovery of poliomyelitis virus from the stools of experimentally infected monkeys and chimpanzees.", "content": "The recovery of poliomyelitis virus from the stools of experimentally infected monkeys and chimpanzees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992664"}
{"pmid": "20992665", "title": "The increased antigenicity of Shigella paradysenteriae (Flexner) in saline-in-mineral-oil emulsion; experiments in mice and rabbits.", "content": "The increased antigenicity of Shigella paradysenteriae (Flexner) in saline-in-mineral-oil emulsion; experiments in mice and rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992665"}
{"pmid": "20992666", "title": "The alcohol problem and the small college.", "content": "The alcohol problem and the small college.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992666"}
{"pmid": "20992667", "title": "The prevention of alcoholism.", "content": "The prevention of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992667"}
{"pmid": "20992668", "title": "The prevention of alcoholism.", "content": "The prevention of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992668"}
{"pmid": "20992669", "title": "STATUTES governing the care and supervision of mental patients in Maryland.", "content": "STATUTES governing the care and supervision of mental patients in Maryland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992669"}
{"pmid": "20992670", "title": "The Toxicology of 1,2-dichloroethane (ethylene dichloride); the effects of daily inhalations.", "content": "The Toxicology of 1,2-dichloroethane (ethylene dichloride); the effects of daily inhalations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992670"}
{"pmid": "20992671", "title": "The microdetermination of antimony in biological material; a spectrographic method.", "content": "The microdetermination of antimony in biological material; a spectrographic method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992671"}
{"pmid": "20992672", "title": "Therapeutic and prophylactic effect of methemoglobinemia in inhalation poisoning by hydrogen cyanide and cyanogen chloride.", "content": "Therapeutic and prophylactic effect of methemoglobinemia in inhalation poisoning by hydrogen cyanide and cyanogen chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992672"}
{"pmid": "20992673", "title": "Electronic counting and size determination of particles in aerosols.", "content": "Electronic counting and size determination of particles in aerosols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992673"}
{"pmid": "20992674", "title": "Chronic phosphorus poisoning.", "content": "Chronic phosphorus poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992674"}
{"pmid": "20992675", "title": "Ventricular fibrillation induced by hydrocarbons and epinephrine.", "content": "Ventricular fibrillation induced by hydrocarbons and epinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992675"}
{"pmid": "20992676", "title": "Mercury hazards in seed treating.", "content": "Mercury hazards in seed treating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992676"}
{"pmid": "20992677", "title": "Atmospheric pollution; a new term and classification covering substances suspended in the air or dissolved by it.", "content": "Atmospheric pollution; a new term and classification covering substances suspended in the air or dissolved by it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992677"}
{"pmid": "20992678", "title": "Effects of high speed vibrating tools on operators engaged in the airplane industry.", "content": "Effects of high speed vibrating tools on operators engaged in the airplane industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992678"}
{"pmid": "20992679", "title": "Occupational diseases in government-owned ordnance explosives plants; observations on their prevalence and control during World War II.", "content": "Occupational diseases in government-owned ordnance explosives plants; observations on their prevalence and control during World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992679"}
{"pmid": "20992680", "title": "Trinitrotoluene experience.", "content": "Trinitrotoluene experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992680"}
{"pmid": "20992681", "title": "Tetryl dermatitis and other effects.", "content": "Tetryl dermatitis and other effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992681"}
{"pmid": "20992682", "title": "Nitrogen oxides poisoning.", "content": "Nitrogen oxides poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992682"}
{"pmid": "20992683", "title": "Industrial hygiene in 1945.", "content": "Industrial hygiene in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992683"}
{"pmid": "20992689", "title": "Hereditary (sex-linked?) anemia.", "content": "Hereditary (sex-linked?) anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992689"}
{"pmid": "20992690", "title": "Blood changes related to sulfonamide therapy; aplastic anemia associated with sulfonamide therapy.", "content": "Blood changes related to sulfonamide therapy; aplastic anemia associated with sulfonamide therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992690"}
{"pmid": "20992691", "title": "Blood changes related to sulfonamide therapy; granulocytopenia associated with use of sulfonamides.", "content": "Blood changes related to sulfonamide therapy; granulocytopenia associated with use of sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992691"}
{"pmid": "20992692", "title": "Blood changes related to sulfonamide therapy; treatment of granulocytopenia with folic acid and pyridoxine hydrochloride.", "content": "Blood changes related to sulfonamide therapy; treatment of granulocytopenia with folic acid and pyridoxine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992692"}
{"pmid": "20992693", "title": "Variations in susceptibility to therapeutic malaria.", "content": "Variations in susceptibility to therapeutic malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992693"}
{"pmid": "20992694", "title": "Interference dissociation; an early finding in acute rheumatic fever.", "content": "Interference dissociation; an early finding in acute rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992694"}
{"pmid": "20992695", "title": "Changes in the cardiovascular system in scrub typhus in early convalescence.", "content": "Changes in the cardiovascular system in scrub typhus in early convalescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992695"}
{"pmid": "20992696", "title": "An 18-hour concentration test of kidney function.", "content": "An 18-hour concentration test of kidney function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992696"}
{"pmid": "20992697", "title": "The relationship between packed red cell volumes and lymphocyte counts.", "content": "The relationship between packed red cell volumes and lymphocyte counts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992697"}
{"pmid": "20992698", "title": "The sedimentation rate as an aid in the diagnosis of acute poliomyelitis.", "content": "The sedimentation rate as an aid in the diagnosis of acute poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992698"}
{"pmid": "20992699", "title": "The epidemiologic significance of amplitudes of seasonal fluctuation in infectious diseases.", "content": "The epidemiologic significance of amplitudes of seasonal fluctuation in infectious diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992699"}
{"pmid": "20992700", "title": "Penicillin treatment of acute syphilitic nephrosis and iritis; report of a case.", "content": "Penicillin treatment of acute syphilitic nephrosis and iritis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992700"}
{"pmid": "20992701", "title": "Salmonella suipestifer infection in children; a report of 18 cases.", "content": "Salmonella suipestifer infection in children; a report of 18 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992701"}
{"pmid": "20992702", "title": "The incidence of palpable pulsations in convalescent trench foot; an analysis of 500 patients at an Army general hospital.", "content": "The incidence of palpable pulsations in convalescent trench foot; an analysis of 500 patients at an Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992702"}
{"pmid": "20992703", "title": "Basal metabolism in childhood; current progress.", "content": "Basal metabolism in childhood; current progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992703"}
{"pmid": "20992704", "title": "Puerperal infection.", "content": "Puerperal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992704"}
{"pmid": "20992705", "title": "Studies on nutrition.", "content": "Studies on nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992705"}
{"pmid": "20992706", "title": "Electroencephalographic evaluation of the effect of penicillin in treatment of central nervous system syphilis.", "content": "Electroencephalographic evaluation of the effect of penicillin in treatment of central nervous system syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992706"}
{"pmid": "20992718", "title": "Total war on cancer.", "content": "Total war on cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992718"}
{"pmid": "20992719", "title": "Some observations on liver function tests in diseases not primarily hepatic.", "content": "Some observations on liver function tests in diseases not primarily hepatic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992719"}
{"pmid": "20992720", "title": "Rheumatic fever in the R. A. F.; results of treatment at a convalescent centre.", "content": "Rheumatic fever in the R. A. F.; results of treatment at a convalescent centre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992720"}
{"pmid": "20992721", "title": "Erythroblastosis foetalis.", "content": "Erythroblastosis foetalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992721"}
{"pmid": "20992722", "title": "Achromotrichia in tropical malnutrition.", "content": "Achromotrichia in tropical malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992722"}
{"pmid": "20992723", "title": "The conus medullaris syndrome in spinal contusion.", "content": "The conus medullaris syndrome in spinal contusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992723"}
{"pmid": "20992724", "title": "Perforated duodenal ulcer at the age of 12.", "content": "Perforated duodenal ulcer at the age of 12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992724"}
{"pmid": "20992725", "title": "An improvised closed circuit.", "content": "An improvised closed circuit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992725"}
{"pmid": "20992726", "title": "Clinical pathology in the hospital surveys.", "content": "Clinical pathology in the hospital surveys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992726"}
{"pmid": "20992727", "title": "True Mediterranean fever in England.", "content": "True Mediterranean fever in England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992727"}
{"pmid": "20992728", "title": "Shock treatment of bronchial asthma.", "content": "Shock treatment of bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992728"}
{"pmid": "20992729", "title": "The treatment of the healthy and sick diabetic.", "content": "The treatment of the healthy and sick diabetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992729"}
{"pmid": "20992730", "title": "Some chronic diarrheal disorders in early life.", "content": "Some chronic diarrheal disorders in early life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992730"}
{"pmid": "20992731", "title": "Surgical treatment of peptic ulcer.", "content": "Surgical treatment of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992731"}
{"pmid": "20992742", "title": "A comparative study of some commercial preparations of oral penicillin.", "content": "A comparative study of some commercial preparations of oral penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992742"}
{"pmid": "20992743", "title": "Treatment in mental disease; especially the psychoneuroses.", "content": "Treatment in mental disease; especially the psychoneuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992743"}
{"pmid": "20992744", "title": "Psychogenic factors in bronchial asthma.", "content": "Psychogenic factors in bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992744"}
{"pmid": "20992746", "title": "Development of an anastomosis between the coronary vessels and a transplanted internal mammary artery.", "content": "Development of an anastomosis between the coronary vessels and a transplanted internal mammary artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992746"}
{"pmid": "20992747", "title": "Cysts of the genital ducts, Müllerian and Wolffian.", "content": "Cysts of the genital ducts, Müllerian and Wolffian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992747"}
{"pmid": "20992749", "title": "A gallery of cases.", "content": "A gallery of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992749"}
{"pmid": "20992750", "title": "Acute suppurative ventriculitis secondary to brain abscess with recovery.", "content": "Acute suppurative ventriculitis secondary to brain abscess with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992750"}
{"pmid": "20992752", "title": "Infectious lymphocytosis.", "content": "Infectious lymphocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992752"}
{"pmid": "20992753", "title": "Prostatitis on the North Atlantic service.", "content": "Prostatitis on the North Atlantic service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992753"}
{"pmid": "20992755", "title": "Importance of radical treatment in acute hand injuries.", "content": "Importance of radical treatment in acute hand injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992755"}
{"pmid": "20992754", "title": "Protruded cervical intervertebral discs; a cause of brachial neuritis.", "content": "Protruded cervical intervertebral discs; a cause of brachial neuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992754"}
{"pmid": "20992756", "title": "Primary idiopathic segmental infarction of the greater omentum.", "content": "Primary idiopathic segmental infarction of the greater omentum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992756"}
{"pmid": "20992757", "title": "An unusual case of pulmonary tuberculosis.", "content": "An unusual case of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992757"}
{"pmid": "20992759", "title": "Thyrotoxicosis, diabetes and thiouracil.", "content": "Thyrotoxicosis, diabetes and thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992759"}
{"pmid": "20992760", "title": "Cystic organoid teratoma; report of a case.", "content": "Cystic organoid teratoma; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992760"}
{"pmid": "20992761", "title": "A review of health conditions in children in post-war Europe.", "content": "A review of health conditions in children in post-war Europe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992761"}
{"pmid": "20992762", "title": "A clamp for control of continuous infusions.", "content": "A clamp for control of continuous infusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992762"}
{"pmid": "20992763", "title": "PRESENT status of penicillin in syphilis treatment.", "content": "PRESENT status of penicillin in syphilis treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992763"}
{"pmid": "20992764", "title": "Injuries of the nerves and tendons of the hand.", "content": "Injuries of the nerves and tendons of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992764"}
{"pmid": "20992765", "title": "The present status of fluorine in relation to tooth decay.", "content": "The present status of fluorine in relation to tooth decay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992765"}
{"pmid": "20992766", "title": "[Hemochromatosis].", "content": "[Hemochromatosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992766"}
{"pmid": "20992778", "title": "Medicine during World War II.", "content": "Medicine during World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992778"}
{"pmid": "20992779", "title": "Transverse myelitis.", "content": "Transverse myelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992779"}
{"pmid": "20992780", "title": "The treatment of psychopathic personality.", "content": "The treatment of psychopathic personality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992780"}
{"pmid": "20992781", "title": "Legg Perthes' disease; a report of five cases in adult men.", "content": "Legg Perthes' disease; a report of five cases in adult men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992781"}
{"pmid": "20992782", "title": "Voluntary funds in cancer control.", "content": "Voluntary funds in cancer control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992782"}
{"pmid": "20992783", "title": "Organization of a group clinic.", "content": "Organization of a group clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992783"}
{"pmid": "20992784", "title": "The job of the state and county societies in medical public relations.", "content": "The job of the state and county societies in medical public relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992784"}
{"pmid": "20992785", "title": "Health education; indispensable.", "content": "Health education; indispensable.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992785"}
{"pmid": "20992794", "title": "The chest lead diagram (CLD).", "content": "The chest lead diagram (CLD).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992794"}
{"pmid": "20992795", "title": "Antibiotic substances and the control of fungi.", "content": "Antibiotic substances and the control of fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992795"}
{"pmid": "20992786", "title": "Torula histolytica (cryptococcus hominis) infection; report of case refractory to sulfonamides.", "content": "Torula histolytica (cryptococcus hominis) infection; report of case refractory to sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992786"}
{"pmid": "20992796", "title": "Observations on the cell changes in molluscum contagiosum, Paget's disease of the skin and some carcinomatous conditions.", "content": "Observations on the cell changes in molluscum contagiosum, Paget's disease of the skin and some carcinomatous conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992796"}
{"pmid": "20992788", "title": "Myxedema with cholesterosis and massive pericardial effusion.", "content": "Myxedema with cholesterosis and massive pericardial effusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992788"}
{"pmid": "20992797", "title": "Correlation between salicylate dosage and plasma level and the prothrombin content of the blood.", "content": "Correlation between salicylate dosage and plasma level and the prothrombin content of the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992797"}
{"pmid": "20992789", "title": "Lymphoma of the small intestine in childhood.", "content": "Lymphoma of the small intestine in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992789"}
{"pmid": "20992798", "title": "The number of amino acids liberated from various dietary proteins by the proteinases of the digestive tract and some conclusions as to the basic structure of these proteins.", "content": "The number of amino acids liberated from various dietary proteins by the proteinases of the digestive tract and some conclusions as to the basic structure of these proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992798"}
{"pmid": "20992790", "title": "Renal hemangiomata.", "content": "Renal hemangiomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992790"}
{"pmid": "20992799", "title": "The esophago-cardiogram and the intrapulmonic cardiogram (observations on rabbits).", "content": "The esophago-cardiogram and the intrapulmonic cardiogram (observations on rabbits).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992799"}
{"pmid": "20992793", "title": "Rehabilitation in the obese by lipectomy.", "content": "Rehabilitation in the obese by lipectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992793"}
{"pmid": "20992787", "title": "Tularemia; a case treated with streptomycin.", "content": "Tularemia; a case treated with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992787"}
{"pmid": "20992801", "title": "A consideration of anoxia in the mechanism of death in acute malarial infections.", "content": "A consideration of anoxia in the mechanism of death in acute malarial infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992801"}
{"pmid": "20992800", "title": "Extrasystoles in man produced by direct mechanical irritation of the left or right ventricle.", "content": "Extrasystoles in man produced by direct mechanical irritation of the left or right ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992800"}
{"pmid": "20992802", "title": "A neurogenic mechanism of acute pulmonary edema.", "content": "A neurogenic mechanism of acute pulmonary edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992802"}
{"pmid": "20992792", "title": "Leiomyosarcoma of the stomach; a case report.", "content": "Leiomyosarcoma of the stomach; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992792"}
{"pmid": "20992791", "title": "Rh survey.", "content": "Rh survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992791"}
{"pmid": "20992803", "title": "SANITARY engineering; an ally of medicine.", "content": "SANITARY engineering; an ally of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992803"}
{"pmid": "20992804", "title": "Functional disease vs. abdominal surgery.", "content": "Functional disease vs. abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992804"}
{"pmid": "20992805", "title": "Some reasons for ocular discomfort.", "content": "Some reasons for ocular discomfort.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992805"}
{"pmid": "20992806", "title": "The Chicago plan of tuberculosis control.", "content": "The Chicago plan of tuberculosis control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992806"}
{"pmid": "20992807", "title": "Pilonidal sinus; statistical review of 300 cases.", "content": "Pilonidal sinus; statistical review of 300 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992807"}
{"pmid": "20992808", "title": "Teamwork in medicine; the Woman's Auxiliary as a member of the team.", "content": "Teamwork in medicine; the Woman's Auxiliary as a member of the team.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992808"}
{"pmid": "20992809", "title": "Pseudo-spirochaetes in blood.", "content": "Pseudo-spirochaetes in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992809"}
{"pmid": "20992810", "title": "Granulocytopenia from the combined use of thiouracil and sulfonamides.", "content": "Granulocytopenia from the combined use of thiouracil and sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992810"}
{"pmid": "20992829", "title": "Chemotherapy.", "content": "Chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992829"}
{"pmid": "20992830", "title": "Vitamins in general practice.", "content": "Vitamins in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992830"}
{"pmid": "20992832", "title": "Giardiasis.", "content": "Giardiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992832"}
{"pmid": "20992831", "title": "Penicillin in chancroid ulcers of pudenda.", "content": "Penicillin in chancroid ulcers of pudenda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992831"}
{"pmid": "20992833", "title": "The auricular wave; an exhaustive inquiry into the physiological and pathological variations of the P wave (or auricular wave) of the electrocardiogram.", "content": "The auricular wave; an exhaustive inquiry into the physiological and pathological variations of the P wave (or auricular wave) of the electrocardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992833"}
{"pmid": "20992834", "title": "Carcinoma of the larynx.", "content": "Carcinoma of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992834"}
{"pmid": "20992835", "title": "The Ascheim-Zondek test in the diagnosis of tumours.", "content": "The Ascheim-Zondek test in the diagnosis of tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992835"}
{"pmid": "20992836", "title": "Diagnosis of bone tumours by aspiration; a review of 80 cases.", "content": "Diagnosis of bone tumours by aspiration; a review of 80 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992836"}
{"pmid": "20992837", "title": "Mitral stenosis and pulmonary tuberculosis.", "content": "Mitral stenosis and pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992837"}
{"pmid": "20992838", "title": "Local use of penicillin in ophthalmology.", "content": "Local use of penicillin in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992838"}
{"pmid": "20992839", "title": "Cutaneous anthrax; report of twenty-five cases.", "content": "Cutaneous anthrax; report of twenty-five cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992839"}
{"pmid": "20992840", "title": "Studies in glycosuria and diabetes mellitus in selectees.", "content": "Studies in glycosuria and diabetes mellitus in selectees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992840"}
{"pmid": "20992841", "title": "The use of para-aminobenzoic acid in endemic (murine) typhus.", "content": "The use of para-aminobenzoic acid in endemic (murine) typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992841"}
{"pmid": "20992842", "title": "Arteriovenous aneurysm following surgical operations.", "content": "Arteriovenous aneurysm following surgical operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992842"}
{"pmid": "20992843", "title": "Salmonella typhimurium food infection from Colby cheese.", "content": "Salmonella typhimurium food infection from Colby cheese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992843"}
{"pmid": "20992844", "title": "Fluids in congestive heart failure.", "content": "Fluids in congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992844"}
{"pmid": "20992845", "title": "Primary tularemic pneumonia treated with streptomycin.", "content": "Primary tularemic pneumonia treated with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992845"}
{"pmid": "20992846", "title": "Penicillin in infections involving the central nervous system and skull.", "content": "Penicillin in infections involving the central nervous system and skull.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992846"}
{"pmid": "20992847", "title": "Potassium deficiency occurring during the treatment of diabetic acidosis.", "content": "Potassium deficiency occurring during the treatment of diabetic acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992847"}
{"pmid": "20992848", "title": "Methods of local therapy for tinea capitis due to Microsporon audouini.", "content": "Methods of local therapy for tinea capitis due to Microsporon audouini.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992848"}
{"pmid": "20992849", "title": "Intrauterine respiration of the human fetus.", "content": "Intrauterine respiration of the human fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992849"}
{"pmid": "20992850", "title": "Synthetic folic acid therapy in pernicious anemia.", "content": "Synthetic folic acid therapy in pernicious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992850"}
{"pmid": "20992851", "title": "Charter for world health.", "content": "Charter for world health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992851"}
{"pmid": "20992852", "title": "Hyperthyroidism with malignant exophthalmos.", "content": "Hyperthyroidism with malignant exophthalmos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992852"}
{"pmid": "20992853", "title": "The x-ray diagnosis of lesions in the region of the sella turcica.", "content": "The x-ray diagnosis of lesions in the region of the sella turcica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992853"}
{"pmid": "20992854", "title": "Tropical medicine; yellow fever.", "content": "Tropical medicine; yellow fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992854"}
{"pmid": "20992855", "title": "Treatment of coronary thrombosis.", "content": "Treatment of coronary thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992855"}
{"pmid": "20992856", "title": "Public health problems in Florida.", "content": "Public health problems in Florida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992856"}
{"pmid": "20992857", "title": "Anaerobic streptococcus infection about the rectum in the supralevator space.", "content": "Anaerobic streptococcus infection about the rectum in the supralevator space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992857"}
{"pmid": "20992859", "title": "Anterior poliomyelitis.", "content": "Anterior poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992859"}
{"pmid": "20992858", "title": "Conservative therapy of cardiac tamponade resulting from wounds of the heart; report of four cases.", "content": "Conservative therapy of cardiac tamponade resulting from wounds of the heart; report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992858"}
{"pmid": "20992861", "title": "Surgical treatment of the undescended testicle.", "content": "Surgical treatment of the undescended testicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992861"}
{"pmid": "20992860", "title": "The evolution of the treatment of pilonidal cysts and sinuses.", "content": "The evolution of the treatment of pilonidal cysts and sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992860"}
{"pmid": "20992862", "title": "Clinical observations on the use of penicillin.", "content": "Clinical observations on the use of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992862"}
{"pmid": "20992863", "title": "Mesenteric cysts.", "content": "Mesenteric cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992863"}
{"pmid": "20992865", "title": "The mental hospital of the future.", "content": "The mental hospital of the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992865"}
{"pmid": "20992864", "title": "The tonsil stump and its removal.", "content": "The tonsil stump and its removal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992864"}
{"pmid": "20992866", "title": "Thyroid disease.", "content": "Thyroid disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992866"}
{"pmid": "20992867", "title": "Thiouracil in the treatment of Graves' disease.", "content": "Thiouracil in the treatment of Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992867"}
{"pmid": "20992868", "title": "Ruptured intracranial aneurysms.", "content": "Ruptured intracranial aneurysms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992868"}
{"pmid": "20992869", "title": "Subacute bacterial endocarditis in a patient with congenital heart disease; cure with penicillin.", "content": "Subacute bacterial endocarditis in a patient with congenital heart disease; cure with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992869"}
{"pmid": "20992870", "title": "A survey on the uses of penicillin in diseases of the eye.", "content": "A survey on the uses of penicillin in diseases of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992870"}
{"pmid": "20992871", "title": "PERTUSSIS in Iowa.", "content": "PERTUSSIS in Iowa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992871"}
{"pmid": "20992872", "title": "Medical history of Dickinson County.", "content": "Medical history of Dickinson County.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992872"}
{"pmid": "20992873", "title": "A nutritional survey of starvation in a group of young men.", "content": "A nutritional survey of starvation in a group of young men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992873"}
{"pmid": "20992874", "title": "The action of thiobismol on therapeutic quartan malaria.", "content": "The action of thiobismol on therapeutic quartan malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992874"}
{"pmid": "20992875", "title": "The distribution of atabrine in the blood, the skin, and its appendages; methods for the rapid and simple detection of the presence of atabrine in blood, skin, and nails.", "content": "The distribution of atabrine in the blood, the skin, and its appendages; methods for the rapid and simple detection of the presence of atabrine in blood, skin, and nails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992875"}
{"pmid": "20992876", "title": "Pyribenzamine (n'-pyridyl-n'-benzyl-n-dimethylethylenediamine HC1), an antagonist of histamine.", "content": "Pyribenzamine (n'-pyridyl-n'-benzyl-n-dimethylethylenediamine HC1), an antagonist of histamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992876"}
{"pmid": "20992877", "title": "Studies on the toxicity of sulfonamide drugs porphyrin excretion by a patient treated with sulfadiazine and later with sulfanilamide.", "content": "Studies on the toxicity of sulfonamide drugs porphyrin excretion by a patient treated with sulfadiazine and later with sulfanilamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992877"}
{"pmid": "20992878", "title": "Observations on the activity in vitro of succinylsulfathiazole and phthalylsulfathiazole.", "content": "Observations on the activity in vitro of succinylsulfathiazole and phthalylsulfathiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992878"}
{"pmid": "20992879", "title": "Fate of sodium ricinoleate after oral administration to white rats.", "content": "Fate of sodium ricinoleate after oral administration to white rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992879"}
{"pmid": "20992880", "title": "Observations on the effect of lowered oxygen tension on sicklemia and sickle cell anemia among military flying personnel.", "content": "Observations on the effect of lowered oxygen tension on sicklemia and sickle cell anemia among military flying personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992880"}
{"pmid": "20992881", "title": "The bone marrow in hemophilia during life; a study of the cellular elements and the coagulation time of the marrow blood.", "content": "The bone marrow in hemophilia during life; a study of the cellular elements and the coagulation time of the marrow blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992881"}
{"pmid": "20992882", "title": "An unusual case of generalized anasarca appearing in an impounded dog with cirrhosis of the liver.", "content": "An unusual case of generalized anasarca appearing in an impounded dog with cirrhosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992882"}
{"pmid": "20992883", "title": "Sensitization of Rh-positive patients by the Rh factor.", "content": "Sensitization of Rh-positive patients by the Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992883"}
{"pmid": "20992884", "title": "The traumatic effects of positive intratracheal pressures.", "content": "The traumatic effects of positive intratracheal pressures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992884"}
{"pmid": "20992885", "title": "An apparatus for measuring the retained dose of inhaled substances.", "content": "An apparatus for measuring the retained dose of inhaled substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992885"}
{"pmid": "20992886", "title": "The relative efficiency of water centrifugal sedimentation and other methods of stool examination for diagnosis of Schistosomiasis japonica.", "content": "The relative efficiency of water centrifugal sedimentation and other methods of stool examination for diagnosis of Schistosomiasis japonica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992886"}
{"pmid": "20992887", "title": "A presumptive medium for differentiating paracolon from Salmonella cultures.", "content": "A presumptive medium for differentiating paracolon from Salmonella cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992887"}
{"pmid": "20992897", "title": "A study of the construction, impairment and reconstruction of the pelvic floor.", "content": "A study of the construction, impairment and reconstruction of the pelvic floor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992897"}
{"pmid": "20992898", "title": "INTERPRETATION of serologic reports for syphilis; with special reference to false positive reactions.", "content": "INTERPRETATION of serologic reports for syphilis; with special reference to false positive reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992898"}
{"pmid": "20992899", "title": "SYPHILIS and penicillin therapy.", "content": "SYPHILIS and penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992899"}
{"pmid": "20992900", "title": "The possibilities of cure in far-advanced growths; cancer still localized at necropsy.", "content": "The possibilities of cure in far-advanced growths; cancer still localized at necropsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992900"}
{"pmid": "20992901", "title": "Palliative roentgen therapy of bone metastases from breast carcinoma.", "content": "Palliative roentgen therapy of bone metastases from breast carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992901"}
{"pmid": "20992903", "title": "Use of large daily injections of penicillin emulsion in dermatology.", "content": "Use of large daily injections of penicillin emulsion in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992903"}
{"pmid": "20992902", "title": "Resistance to antibiotic agents.", "content": "Resistance to antibiotic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992902"}
{"pmid": "20992904", "title": "Medicine in Missouri.", "content": "Medicine in Missouri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992904"}
{"pmid": "20992912", "title": "Acute otitis media; its management by the general practitioner and pediatrician.", "content": "Acute otitis media; its management by the general practitioner and pediatrician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992912"}
{"pmid": "20992913", "title": "Low spinal anesthesia in obstetrics.", "content": "Low spinal anesthesia in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992913"}
{"pmid": "20992914", "title": "The practical treatment of neuroses.", "content": "The practical treatment of neuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992914"}
{"pmid": "20992907", "title": "Successful obstetrical management.", "content": "Successful obstetrical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992907"}
{"pmid": "20992906", "title": "A new concept of proctology.", "content": "A new concept of proctology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992906"}
{"pmid": "20992915", "title": "Nasal fractures.", "content": "Nasal fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992915"}
{"pmid": "20992908", "title": "Symptomatology of abnormities of circulatory and vasculary pressure in ocular and iris diagnosis.", "content": "Symptomatology of abnormities of circulatory and vasculary pressure in ocular and iris diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992908"}
{"pmid": "20992905", "title": "Drugs used homeopathically as prophylactic measures.", "content": "Drugs used homeopathically as prophylactic measures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992905"}
{"pmid": "20992909", "title": "A new conception of the origin of the tonsil and the proper care of its pathology.", "content": "A new conception of the origin of the tonsil and the proper care of its pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992909"}
{"pmid": "20992918", "title": "Effects of slow starvation.", "content": "Effects of slow starvation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992918"}
{"pmid": "20992911", "title": "The old school canine distemper.", "content": "The old school canine distemper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992911"}
{"pmid": "20992920", "title": "Masked syphilis; dangers of penicillin therapy.", "content": "Masked syphilis; dangers of penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992920"}
{"pmid": "20992919", "title": "Tubocurarine chloride as an adjunct to anaesthesia; report on 180 cases.", "content": "Tubocurarine chloride as an adjunct to anaesthesia; report on 180 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992919"}
{"pmid": "20992910", "title": "Constipation.", "content": "Constipation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992910"}
{"pmid": "20992921", "title": "Preservation of the vein in operations for arteriovenous fistula.", "content": "Preservation of the vein in operations for arteriovenous fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992921"}
{"pmid": "20992922", "title": "Oil sterilisation of syringes.", "content": "Oil sterilisation of syringes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992922"}
{"pmid": "20992923", "title": "Tuberculous glands and sinuses treated with calciferol.", "content": "Tuberculous glands and sinuses treated with calciferol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992923"}
{"pmid": "20992924", "title": "Antecedents of cancer.", "content": "Antecedents of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992924"}
{"pmid": "20992925", "title": "Chemotherapy of tuberculosis.", "content": "Chemotherapy of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992925"}
{"pmid": "20992926", "title": "Effects of use and disuse on nerve and muscle.", "content": "Effects of use and disuse on nerve and muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992926"}
{"pmid": "20992927", "title": "Penicillin sensitivity of Bact. typhosum.", "content": "Penicillin sensitivity of Bact. typhosum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992927"}
{"pmid": "20992928", "title": "Sulphathiazole and penicillin typhoid fever; report of six cases.", "content": "Sulphathiazole and penicillin typhoid fever; report of six cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992928"}
{"pmid": "20992929", "title": "Malaria transmission in Borneo.", "content": "Malaria transmission in Borneo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992929"}
{"pmid": "20992930", "title": "Penicillin via Fallopian tubes.", "content": "Penicillin via Fallopian tubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992930"}
{"pmid": "20992931", "title": "Digestibility of high-extraction wheaten flours.", "content": "Digestibility of high-extraction wheaten flours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992931"}
{"pmid": "20992932", "title": "REGIONAL boards.", "content": "REGIONAL boards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992932"}
{"pmid": "20992933", "title": "Memorandum on B. C. G.; a British review.", "content": "Memorandum on B. C. G.; a British review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992933"}
{"pmid": "20992934", "title": "Polyarteritis nodosa and syphilis.", "content": "Polyarteritis nodosa and syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992934"}
{"pmid": "20992939", "title": "The differential diagnosis of splenomegaly of adults.", "content": "The differential diagnosis of splenomegaly of adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992939"}
{"pmid": "20992940", "title": "Roentgen therapy for leukemia.", "content": "Roentgen therapy for leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992940"}
{"pmid": "20992941", "title": "Treatment of headache.", "content": "Treatment of headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992941"}
{"pmid": "20992942", "title": "The problem of blackout and unconsciousness in aviators.", "content": "The problem of blackout and unconsciousness in aviators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992942"}
{"pmid": "20992943", "title": "Clinical use of thiouracil.", "content": "Clinical use of thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992943"}
{"pmid": "20992944", "title": "The clinical administration of streptomycin.", "content": "The clinical administration of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992944"}
{"pmid": "20992945", "title": "The nonsurgical management of bronchiectasis.", "content": "The nonsurgical management of bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992945"}
{"pmid": "20992947", "title": "The abuse of sedative drugs in the practice of medicine.", "content": "The abuse of sedative drugs in the practice of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992947"}
{"pmid": "20992946", "title": "The thiocyanates in the treatment of hypertensive disease.", "content": "The thiocyanates in the treatment of hypertensive disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992946"}
{"pmid": "20992948", "title": "Penicillin in the treatment of syphilis.", "content": "Penicillin in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992948"}
{"pmid": "20992949", "title": "The value of gastroscopy in the diagnosis of gastric disease.", "content": "The value of gastroscopy in the diagnosis of gastric disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992949"}
{"pmid": "20992950", "title": "Medical problems in cases of acute abdominal pain.", "content": "Medical problems in cases of acute abdominal pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992950"}
{"pmid": "20992951", "title": "The use of the newer sulfonamides and antibiotics in intestinal diseases.", "content": "The use of the newer sulfonamides and antibiotics in intestinal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992951"}
{"pmid": "20992952", "title": "The use of various kinds of insulin.", "content": "The use of various kinds of insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992952"}
{"pmid": "20992953", "title": "An appraisal of radium therapy.", "content": "An appraisal of radium therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992953"}
{"pmid": "20992954", "title": "Chancroid of the uterine cervix.", "content": "Chancroid of the uterine cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992954"}
{"pmid": "20992955", "title": "Habitual abortion.", "content": "Habitual abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992955"}
{"pmid": "20992956", "title": "The clinical picture of papataci fever, especially in Palestine.", "content": "The clinical picture of papataci fever, especially in Palestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992956"}
{"pmid": "20992957", "title": "The relationship of food to health.", "content": "The relationship of food to health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992957"}
{"pmid": "20992958", "title": "Some complications and sequelae of the prophylactic inoculations.", "content": "Some complications and sequelae of the prophylactic inoculations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992958"}
{"pmid": "20992959", "title": "Hernia through the foramen of Winslow emerging through the gastro-hepatic omentum.", "content": "Hernia through the foramen of Winslow emerging through the gastro-hepatic omentum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992959"}
{"pmid": "20992960", "title": "X-ray diagnosis in paediatrics [book review].", "content": "X-ray diagnosis in paediatrics [book review].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992960"}
{"pmid": "20992961", "title": "REPORT on the remuneration of general practitioners.", "content": "REPORT on the remuneration of general practitioners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992961"}
{"pmid": "20992962", "title": "Early mitral stenosis.", "content": "Early mitral stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992962"}
{"pmid": "20992963", "title": "Hypoplastic anaemia.", "content": "Hypoplastic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992963"}
{"pmid": "20992965", "title": "Penicillin-resistant staphylococci in wounds; a report based on a study of 59 cases of infected war wounds.", "content": "Penicillin-resistant staphylococci in wounds; a report based on a study of 59 cases of infected war wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992965"}
{"pmid": "20992964", "title": "Tsutsugamushi disease; attempted preparation of a prophylactic vaccine from fertile hens' eggs experimentally infected with the virus.", "content": "Tsutsugamushi disease; attempted preparation of a prophylactic vaccine from fertile hens' eggs experimentally infected with the virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992964"}
{"pmid": "20992966", "title": "The care of patients with severe asthmatic attacks.", "content": "The care of patients with severe asthmatic attacks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992966"}
{"pmid": "20992967", "title": "Monilial vaginitis; a report of 58 cases.", "content": "Monilial vaginitis; a report of 58 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992967"}
{"pmid": "20992968", "title": "A laboratory study of Monilia albicans.", "content": "A laboratory study of Monilia albicans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992968"}
{"pmid": "20992969", "title": "YAWNING.", "content": "YAWNING.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992969"}
{"pmid": "20992970", "title": "The industrial medical service.", "content": "The industrial medical service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992970"}
{"pmid": "20992971", "title": "Treatment of cancer of the larynx.", "content": "Treatment of cancer of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992971"}
{"pmid": "20992972", "title": "The treatment of general paralysis of the insane (dementia paralytica).", "content": "The treatment of general paralysis of the insane (dementia paralytica).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992972"}
{"pmid": "20992973", "title": "The abnormal infant.", "content": "The abnormal infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992973"}
{"pmid": "20992974", "title": "The modern treatment of corneal opacity.", "content": "The modern treatment of corneal opacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992974"}
{"pmid": "20992976", "title": "Diagnosis and treatment of non-tubercular urinary infections.", "content": "Diagnosis and treatment of non-tubercular urinary infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992976"}
{"pmid": "20992975", "title": "Diagnosis and treatment of injuries of the semilunar cartilages of the knee joint.", "content": "Diagnosis and treatment of injuries of the semilunar cartilages of the knee joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992975"}
{"pmid": "20992977", "title": "Visual education.", "content": "Visual education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992977"}
{"pmid": "20992978", "title": "Mental deficiency services.", "content": "Mental deficiency services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992978"}
{"pmid": "20992979", "title": "The treatment of gout.", "content": "The treatment of gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992979"}
{"pmid": "20992980", "title": "Differential diagnosis of the acute abdomen in children.", "content": "Differential diagnosis of the acute abdomen in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992980"}
{"pmid": "20992981", "title": "Sexual inversion and the English law.", "content": "Sexual inversion and the English law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992981"}
{"pmid": "20992982", "title": "Tumours of the intracranial blood vessels.", "content": "Tumours of the intracranial blood vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992982"}
{"pmid": "20992983", "title": "The treatment of the decompensated heart.", "content": "The treatment of the decompensated heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992983"}
{"pmid": "20992984", "title": "The treatment of skin disease with intramuscular penicillin.", "content": "The treatment of skin disease with intramuscular penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992984"}
{"pmid": "20992985", "title": "India's health problem.", "content": "India's health problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992985"}
{"pmid": "20992986", "title": "Detachment of the retina.", "content": "Detachment of the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992986"}
{"pmid": "20992987", "title": "Cancer of the colon.", "content": "Cancer of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992987"}
{"pmid": "20992989", "title": "Detachment of the retina.", "content": "Detachment of the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992989"}
{"pmid": "20992988", "title": "Late middle age; our arrival; adult life.", "content": "Late middle age; our arrival; adult life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992988"}
{"pmid": "20992990", "title": "Late middle age; our arrival; early middle life.", "content": "Late middle age; our arrival; early middle life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992990"}
{"pmid": "20992991", "title": "Detachment of the retina.", "content": "Detachment of the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992991"}
{"pmid": "20992992", "title": "Cancer of the rectum.", "content": "Cancer of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992992"}
{"pmid": "20992993", "title": "Late middle age, V.", "content": "Late middle age, V.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992993"}
{"pmid": "20992997", "title": "Infectious hepatitis.", "content": "Infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992997"}
{"pmid": "20992998", "title": "Pulmonary lobectomy.", "content": "Pulmonary lobectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992998"}
{"pmid": "20992999", "title": "Treatment of cancer of the larynx with special reference to the esophageal voice.", "content": "Treatment of cancer of the larynx with special reference to the esophageal voice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20992999"}
{"pmid": "20993000", "title": "Carcinoma of lung with unusual manifestations.", "content": "Carcinoma of lung with unusual manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993000"}
{"pmid": "20993001", "title": "Histamine cephalgia.", "content": "Histamine cephalgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993001"}
{"pmid": "20993002", "title": "A case of undetermined fever.", "content": "A case of undetermined fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993002"}
{"pmid": "20993003", "title": "Some effects of famine on the population of Greece.", "content": "Some effects of famine on the population of Greece.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993003"}
{"pmid": "20993004", "title": "Wartime population changes in the United States.", "content": "Wartime population changes in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993004"}
{"pmid": "20993005", "title": "Nutritional status of aircraft workers in Southern California; a conspectus of the survey and its field.", "content": "Nutritional status of aircraft workers in Southern California; a conspectus of the survey and its field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993005"}
{"pmid": "20993006", "title": "Urbanization in Latin America.", "content": "Urbanization in Latin America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993006"}
{"pmid": "20993023", "title": "The sociological pathology of medicine.", "content": "The sociological pathology of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993023"}
{"pmid": "20993024", "title": "Brucellosis; clinical aspects.", "content": "Brucellosis; clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993024"}
{"pmid": "20993025", "title": "Progress in the control of brucellosis (Bang's disease) in domestic animals.", "content": "Progress in the control of brucellosis (Bang's disease) in domestic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993025"}
{"pmid": "20993026", "title": "The treatment of medical jaundice.", "content": "The treatment of medical jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993026"}
{"pmid": "20993027", "title": "Hypersensitivity to penicillin simulating serum sickness.", "content": "Hypersensitivity to penicillin simulating serum sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993027"}
{"pmid": "20993028", "title": "Ethylene disulphonate in allergy.", "content": "Ethylene disulphonate in allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993028"}
{"pmid": "20993029", "title": "Ruptured diverticulum of the jejunum.", "content": "Ruptured diverticulum of the jejunum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993029"}
{"pmid": "20993030", "title": "Industrial health in Navy war plants.", "content": "Industrial health in Navy war plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993030"}
{"pmid": "20993031", "title": "Hormonal dyscrasias of the breast.", "content": "Hormonal dyscrasias of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993031"}
{"pmid": "20993032", "title": "Cataract extraction under sodium pentothal.", "content": "Cataract extraction under sodium pentothal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993032"}
{"pmid": "20993033", "title": "Notes on the history of medicine in Fillmore County prior to 1900.", "content": "Notes on the history of medicine in Fillmore County prior to 1900.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993033"}
{"pmid": "20993034", "title": "The treatment of meningitis due to Haemophilus influenzae with streptomycin; a report of nine cases.", "content": "The treatment of meningitis due to Haemophilus influenzae with streptomycin; a report of nine cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993034"}
{"pmid": "20993035", "title": "New experiences in group psychotherapy.", "content": "New experiences in group psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993035"}
{"pmid": "20993036", "title": "Ophthalmology.", "content": "Ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993036"}
{"pmid": "20993037", "title": "FEE schedule approved by the Council of the Massachusetts Medical Society for medical services rendered under the Veterans Administration Medical Care Program.", "content": "FEE schedule approved by the Council of the Massachusetts Medical Society for medical services rendered under the Veterans Administration Medical Care Program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993037"}
{"pmid": "20993038", "title": "[Acute fibrinopurulent mediastinitis].", "content": "[Acute fibrinopurulent mediastinitis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993038"}
{"pmid": "20993040", "title": "The first description of rickets.", "content": "The first description of rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993040"}
{"pmid": "20993039", "title": "[Lung abscess, right lower lobe; broncholiths, with ulceration of right and left bronchi].", "content": "[Lung abscess, right lower lobe; broncholiths, with ulceration of right and left bronchi].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993039"}
{"pmid": "20993041", "title": "Infectious hepatitis in Massachusetts; with a review of present knowledge of the disease.", "content": "Infectious hepatitis in Massachusetts; with a review of present knowledge of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993041"}
{"pmid": "20993042", "title": "Modern governmental medical problems.", "content": "Modern governmental medical problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993042"}
{"pmid": "20993043", "title": "Acute poliomyelitis in pregnancy; its occurrence according to the month of pregnancy and sex of fetus.", "content": "Acute poliomyelitis in pregnancy; its occurrence according to the month of pregnancy and sex of fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993043"}
{"pmid": "20993044", "title": "An unusual case of a foreign body in the neck.", "content": "An unusual case of a foreign body in the neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993044"}
{"pmid": "20993045", "title": "Diseases of the veins.", "content": "Diseases of the veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993045"}
{"pmid": "20993046", "title": "[Benign stricture of common bile duct].", "content": "[Benign stricture of common bile duct].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993046"}
{"pmid": "20993047", "title": "[Benign peptic ulcer].", "content": "[Benign peptic ulcer].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993047"}
{"pmid": "20993048", "title": "Progress in the treatment of syphilis.", "content": "Progress in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993048"}
{"pmid": "20993049", "title": "Current trends in medical care.", "content": "Current trends in medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993049"}
{"pmid": "20993050", "title": "Kew Gardens spotted fever.", "content": "Kew Gardens spotted fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993050"}
{"pmid": "20993051", "title": "Indications for open reduction of fractures.", "content": "Indications for open reduction of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993051"}
{"pmid": "20993052", "title": "Carcinoma of the prostate; fundamentals of present day treatment.", "content": "Carcinoma of the prostate; fundamentals of present day treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993052"}
{"pmid": "20993053", "title": "Nebraska medical service.", "content": "Nebraska medical service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993053"}
{"pmid": "20993054", "title": "Opaque media in X-ray diagnosis.", "content": "Opaque media in X-ray diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993054"}
{"pmid": "20993055", "title": "Considerations on poliomyelitis.", "content": "Considerations on poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993055"}
{"pmid": "20993056", "title": "Evolution of poliomyelitis treatment.", "content": "Evolution of poliomyelitis treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993056"}
{"pmid": "20993057", "title": "Treatment and the results of treatment in anterior poliomyelitis.", "content": "Treatment and the results of treatment in anterior poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993057"}
{"pmid": "20993058", "title": "Functions of a state health department in the control of poliomyelitis.", "content": "Functions of a state health department in the control of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993058"}
{"pmid": "20993060", "title": "Spontaneous occlusion of external iliac artery; a case report.", "content": "Spontaneous occlusion of external iliac artery; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993060"}
{"pmid": "20993059", "title": "The progress of research in poliomyelitis.", "content": "The progress of research in poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993059"}
{"pmid": "20993061", "title": "Ruptured congenital aneurysm of the sinus of Valsalva with superimposed endocarditis; rupture of aortic cusp producing sudden death.", "content": "Ruptured congenital aneurysm of the sinus of Valsalva with superimposed endocarditis; rupture of aortic cusp producing sudden death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993061"}
{"pmid": "20993063", "title": "The role of the orthopedist in the care of fractures.", "content": "The role of the orthopedist in the care of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993063"}
{"pmid": "20993062", "title": "The Thirty-Second Session of Medical College of Ohio, October 15, 1851.", "content": "The Thirty-Second Session of Medical College of Ohio, October 15, 1851.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993062"}
{"pmid": "20993064", "title": "Correction of cicatricial contractures following burns.", "content": "Correction of cicatricial contractures following burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993064"}
{"pmid": "20993065", "title": "The health center.", "content": "The health center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993065"}
{"pmid": "20993116", "title": "Experimental study of the development of resistance to streptomycin by some bacteria commonly found in urinary infections.", "content": "Experimental study of the development of resistance to streptomycin by some bacteria commonly found in urinary infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993116"}
{"pmid": "20993117", "title": "Streptomycin in the treatment of tuberculosis of the urinary tract.", "content": "Streptomycin in the treatment of tuberculosis of the urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993117"}
{"pmid": "20993119", "title": "Treatment and rehabilitation of men with damage of the brain.", "content": "Treatment and rehabilitation of men with damage of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993119"}
{"pmid": "20993118", "title": "The use of the spectrophotometer in capillary tube colorimetry for the determination of reducing substances (glucose), chlorides, ammonia nitrogen, uric acid and creatinine.", "content": "The use of the spectrophotometer in capillary tube colorimetry for the determination of reducing substances (glucose), chlorides, ammonia nitrogen, uric acid and creatinine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993118"}
{"pmid": "20993132", "title": "The folic acid requirement of chicks for growth, feathering and hemoglobin formation.", "content": "The folic acid requirement of chicks for growth, feathering and hemoglobin formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993132"}
{"pmid": "20993133", "title": "Milk as a source of the monkey anti-anemia factor.", "content": "Milk as a source of the monkey anti-anemia factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993133"}
{"pmid": "20993134", "title": "Effect of adrenocorticotrophic hormone on urinary nitrogen excretion in the normal rat.", "content": "Effect of adrenocorticotrophic hormone on urinary nitrogen excretion in the normal rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993134"}
{"pmid": "20993135", "title": "Growth of Japanese B encephalitic virus in the yolk of the developing egg.", "content": "Growth of Japanese B encephalitic virus in the yolk of the developing egg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993135"}
{"pmid": "20993136", "title": "Treatment of experimental syphilis in rabbits with streptomycin.", "content": "Treatment of experimental syphilis in rabbits with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993136"}
{"pmid": "20993137", "title": "Inositol, a constituent of thyroid gland effect on perfused rabbit's heart.", "content": "Inositol, a constituent of thyroid gland effect on perfused rabbit's heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993137"}
{"pmid": "20993138", "title": "Absence of appreciable L. casei factor effect in anti-pernicious anemia liver extract.", "content": "Absence of appreciable L. casei factor effect in anti-pernicious anemia liver extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993138"}
{"pmid": "20993139", "title": "Vagotomy fails to protect against histamine-provoked ulcer.", "content": "Vagotomy fails to protect against histamine-provoked ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993139"}
{"pmid": "20993140", "title": "COMMISSION on ACUTE RESPIRATORY DISEASES. Hemagglutination by amniotic fluid from normal embryonated hen's eggs.", "content": "COMMISSION on ACUTE RESPIRATORY DISEASES. Hemagglutination by amniotic fluid from normal embryonated hen's eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993140"}
{"pmid": "20993141", "title": "Effect of penicillin and streptomycin on bacterial contamination of chick embryos inoculated with unfiltered sputums.", "content": "Effect of penicillin and streptomycin on bacterial contamination of chick embryos inoculated with unfiltered sputums.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993141"}
{"pmid": "20993142", "title": "Role of nitroglycerin in accelerating occurrence of the histamine-provoked ulcer.", "content": "Role of nitroglycerin in accelerating occurrence of the histamine-provoked ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993142"}
{"pmid": "20993143", "title": "Use of bacteriostatic agents in preparation of seed cultures of psittacosis virus.", "content": "Use of bacteriostatic agents in preparation of seed cultures of psittacosis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993143"}
{"pmid": "20993144", "title": "An organic antimony compound with curative and prophylactic activity in experimental trypanosomiasis.", "content": "An organic antimony compound with curative and prophylactic activity in experimental trypanosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993144"}
{"pmid": "20993145", "title": "Concentration of chloride, sodium and potassium in blood of guinea pigs treated with desoxycorticosterone acetate.", "content": "Concentration of chloride, sodium and potassium in blood of guinea pigs treated with desoxycorticosterone acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993145"}
{"pmid": "20993147", "title": "A toxic substance associated with the Gilliam strain of R. orientalis.", "content": "A toxic substance associated with the Gilliam strain of R. orientalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993147"}
{"pmid": "20993146", "title": "Antigenic differences between strains of scrub typhus as demonstrated by cross-neutralization tests.", "content": "Antigenic differences between strains of scrub typhus as demonstrated by cross-neutralization tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993146"}
{"pmid": "20993148", "title": "Effect of distention of jejunum upon tonicity of the cardia of the dog.", "content": "Effect of distention of jejunum upon tonicity of the cardia of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993148"}
{"pmid": "20993149", "title": "Isolation of an antibiotic agent derived from a Phycomyces active in vitro against Trypanosoma equiperdum.", "content": "Isolation of an antibiotic agent derived from a Phycomyces active in vitro against Trypanosoma equiperdum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993149"}
{"pmid": "20993150", "title": "Hypertensinase activity of an 1-aminoacid oxidase preparation and of the venom of Bothrops neuwidii.", "content": "Hypertensinase activity of an 1-aminoacid oxidase preparation and of the venom of Bothrops neuwidii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993150"}
{"pmid": "20993151", "title": "Effect of steroid sex hormones on distribution of alkaline phosphatase in uterus of mouse.", "content": "Effect of steroid sex hormones on distribution of alkaline phosphatase in uterus of mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993151"}
{"pmid": "20993152", "title": "Some factors which decrease arterial saturation in bird malaria-ducks infected with P. lophurae.", "content": "Some factors which decrease arterial saturation in bird malaria-ducks infected with P. lophurae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993152"}
{"pmid": "20993153", "title": "Effects of reduced caloric intake on leucocyte count of the rat.", "content": "Effects of reduced caloric intake on leucocyte count of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993153"}
{"pmid": "20993154", "title": "Influence of streptomycin and promin on proliferation of tubercle bacilli in the tissues of albino rat.", "content": "Influence of streptomycin and promin on proliferation of tubercle bacilli in the tissues of albino rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993154"}
{"pmid": "20993155", "title": "Streptomycin and penicillin resistant staphylococci; influence of pH, body fluids on streptomycin action.", "content": "Streptomycin and penicillin resistant staphylococci; influence of pH, body fluids on streptomycin action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993155"}
{"pmid": "20993156", "title": "Electrophoretic and allergenic analyses of fractions of larvae of Trichinella spiralis.", "content": "Electrophoretic and allergenic analyses of fractions of larvae of Trichinella spiralis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993156"}
{"pmid": "20993157", "title": "Purified rations and the importance of folic acid in mink nutrition.", "content": "Purified rations and the importance of folic acid in mink nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993157"}
{"pmid": "20993158", "title": "Toxicity of choline in the diet of growing chickens.", "content": "Toxicity of choline in the diet of growing chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993158"}
{"pmid": "20993159", "title": "Ulnar-femoral nerve anastomosis in paraplegic rhesus monkey.", "content": "Ulnar-femoral nerve anastomosis in paraplegic rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993159"}
{"pmid": "20993160", "title": "Non-utilization of intravenously administered acetyl- -tryptophane.", "content": "Non-utilization of intravenously administered acetyl- -tryptophane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993160"}
{"pmid": "20993161", "title": "Effect of quinacrine hydrochloride (atabrine) on isolated mammalian heart.", "content": "Effect of quinacrine hydrochloride (atabrine) on isolated mammalian heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993161"}
{"pmid": "20993162", "title": "Control of pH in roller tube cultures.", "content": "Control of pH in roller tube cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993162"}
{"pmid": "20993163", "title": "An apparatus for permitting control of the atmosphere in roller tube cultures.", "content": "An apparatus for permitting control of the atmosphere in roller tube cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993163"}
{"pmid": "20993165", "title": "Abnormalities of amphibian development following exposure of sperm to colchicine.", "content": "Abnormalities of amphibian development following exposure of sperm to colchicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993165"}
{"pmid": "20993164", "title": "The determination of total circulating serum proteins and erythrocyte volumes in normal and protein depleted rats.", "content": "The determination of total circulating serum proteins and erythrocyte volumes in normal and protein depleted rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993164"}
{"pmid": "20993166", "title": "The citric acid and aconitase content of the prostate.", "content": "The citric acid and aconitase content of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993166"}
{"pmid": "20993167", "title": "Loss of fertilizing power of sea-urchin and Urechis sperm treated with univalent antibodies vs. antifertilizin.", "content": "Loss of fertilizing power of sea-urchin and Urechis sperm treated with univalent antibodies vs. antifertilizin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993167"}
{"pmid": "20993168", "title": "Influence of amino acid feeding upon antibody production in protein depleted rats.", "content": "Influence of amino acid feeding upon antibody production in protein depleted rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993168"}
{"pmid": "20993169", "title": "Increased serum phosphatase and hyperprothrombinemia in infectious hepatitis of children.", "content": "Increased serum phosphatase and hyperprothrombinemia in infectious hepatitis of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993169"}
{"pmid": "20993170", "title": "Inhibitory-action of human epidermis on melanin formation.", "content": "Inhibitory-action of human epidermis on melanin formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993170"}
{"pmid": "20993171", "title": "Significance of histamine in trypsin shock as determined by benadryl.", "content": "Significance of histamine in trypsin shock as determined by benadryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993171"}
{"pmid": "20993172", "title": "Studies on the adherence of the epidermis to the corium.", "content": "Studies on the adherence of the epidermis to the corium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993172"}
{"pmid": "20993173", "title": "Distribution of cholesterol, cholesterol esters and phospholipid phosphorus in normal blood.", "content": "Distribution of cholesterol, cholesterol esters and phospholipid phosphorus in normal blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993173"}
{"pmid": "20993174", "title": "Distribution of cholesterol, cholesterol esters and phospholipid phosphorus in blood in thyroid disease.", "content": "Distribution of cholesterol, cholesterol esters and phospholipid phosphorus in blood in thyroid disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993174"}
{"pmid": "20993175", "title": "Relation between metabolic activity and cyanide inhibition in Pelomyxa carolinensis Wilson.", "content": "Relation between metabolic activity and cyanide inhibition in Pelomyxa carolinensis Wilson.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993175"}
{"pmid": "20993176", "title": "Influence of anticholinesterase diisopropylfluorophosphate on cardiovascular and respiratory reflexes of carotid sinus origin.", "content": "Influence of anticholinesterase diisopropylfluorophosphate on cardiovascular and respiratory reflexes of carotid sinus origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993176"}
{"pmid": "20993177", "title": "Effect of insulin, insulin-dextrose, and water diuresis on metabolism of isopropyl alcohol.", "content": "Effect of insulin, insulin-dextrose, and water diuresis on metabolism of isopropyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993177"}
{"pmid": "20993178", "title": "Inhibitory effect of thiamine on vasoconstrictor action of nicotine tested in the Laewen-Trendelenburg preparation.", "content": "Inhibitory effect of thiamine on vasoconstrictor action of nicotine tested in the Laewen-Trendelenburg preparation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993178"}
{"pmid": "20993179", "title": "Development of immunity to reinfection during chemoprophylaxis of trypanosomiasis with a new antimony derivative.", "content": "Development of immunity to reinfection during chemoprophylaxis of trypanosomiasis with a new antimony derivative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993179"}
{"pmid": "20993180", "title": "Pectin adjuvant for oral penicillin.", "content": "Pectin adjuvant for oral penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993180"}
{"pmid": "20993181", "title": "Experiments on the lateral line system of anurans.", "content": "Experiments on the lateral line system of anurans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993181"}
{"pmid": "20993182", "title": "Infectivity of Hemophilus pertussis for the chick embryo.", "content": "Infectivity of Hemophilus pertussis for the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993182"}
{"pmid": "20993183", "title": "Prothrombin level and effect of vitamin K substitutes in thrombocytopenic purpura in rats.", "content": "Prothrombin level and effect of vitamin K substitutes in thrombocytopenic purpura in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993183"}
{"pmid": "20993184", "title": "Control of Salmonella infections in mice by streptomycin.", "content": "Control of Salmonella infections in mice by streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993184"}
{"pmid": "20993186", "title": "Effects of injections of equine gonadotrophin upon the gonads and adrenals of fetal rats.", "content": "Effects of injections of equine gonadotrophin upon the gonads and adrenals of fetal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993186"}
{"pmid": "20993185", "title": "The components of prothrombin.", "content": "The components of prothrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993185"}
{"pmid": "20993187", "title": "Urinary excretion of thiamine as a characteristic of the individual.", "content": "Urinary excretion of thiamine as a characteristic of the individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993187"}
{"pmid": "20993188", "title": "Persistence of elevated values for the thymol turbidity test following infectious hepatitis.", "content": "Persistence of elevated values for the thymol turbidity test following infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993188"}
{"pmid": "20993190", "title": "Reaction of the rat peritoneum to acid colloidal pigments.", "content": "Reaction of the rat peritoneum to acid colloidal pigments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993190"}
{"pmid": "20993189", "title": "A simplified clinical procedure for measurement of glomerular filtration rate and renal plasma flow.", "content": "A simplified clinical procedure for measurement of glomerular filtration rate and renal plasma flow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993189"}
{"pmid": "20993191", "title": "One stage functional hepatectomy in the rat.", "content": "One stage functional hepatectomy in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993191"}
{"pmid": "20993192", "title": "Viruses in activated by mustard (bis(chloroethyl) sulfide) as vaccines.", "content": "Viruses in activated by mustard (bis(chloroethyl) sulfide) as vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993192"}
{"pmid": "20993193", "title": "Experimental chronic hypertension in the rat; structural changes in blood vessels, heart and kidneys.", "content": "Experimental chronic hypertension in the rat; structural changes in blood vessels, heart and kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993193"}
{"pmid": "20993194", "title": "Effect of quick freezing at very low temperatures of donor tissue in corneal transplants.", "content": "Effect of quick freezing at very low temperatures of donor tissue in corneal transplants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993194"}
{"pmid": "20993195", "title": "Fibrinolytic activity in blood serum during pregnancy complicated by hypertensive toxemias.", "content": "Fibrinolytic activity in blood serum during pregnancy complicated by hypertensive toxemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993195"}
{"pmid": "20993196", "title": "Effect of minerals on susceptibility of Swiss mice to Theiler's virus.", "content": "Effect of minerals on susceptibility of Swiss mice to Theiler's virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993196"}
{"pmid": "20993197", "title": "Influence of various pharmacologic substances on the emetic effect of intravenous glutamic acid in dogs.", "content": "Influence of various pharmacologic substances on the emetic effect of intravenous glutamic acid in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993197"}
{"pmid": "20993198", "title": "Experimental acceleration of urine in fetal rats.", "content": "Experimental acceleration of urine in fetal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993198"}
{"pmid": "20993199", "title": "Isolation of a macromolecular constituent with properties of the Lansing strain of poliomyelitis virus.", "content": "Isolation of a macromolecular constituent with properties of the Lansing strain of poliomyelitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993199"}
{"pmid": "20993200", "title": "Electron microscopy of purified Lansing virus.", "content": "Electron microscopy of purified Lansing virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993200"}
{"pmid": "20993201", "title": "Rôle of bacteria in the production of tourniquet shock in rats.", "content": "Rôle of bacteria in the production of tourniquet shock in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993201"}
{"pmid": "20993202", "title": "Three new Salmonella types; S. richmond, S. daytona and S. tallahassee.", "content": "Three new Salmonella types; S. richmond, S. daytona and S. tallahassee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993202"}
{"pmid": "20993203", "title": "Flagella and flagellar antigens in nonmotile Salmonella cultures.", "content": "Flagella and flagellar antigens in nonmotile Salmonella cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993203"}
{"pmid": "20993204", "title": "Submerged growth of tubercle bacilli from pathologic material in Dubos' medium.", "content": "Submerged growth of tubercle bacilli from pathologic material in Dubos' medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993204"}
{"pmid": "20993205", "title": "Significance of thromboplastic activity of antigens used in complement fixation tests.", "content": "Significance of thromboplastic activity of antigens used in complement fixation tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993205"}
{"pmid": "20993206", "title": "A note on the relationship between the intermedius and minimus types of C. diphtheriae.", "content": "A note on the relationship between the intermedius and minimus types of C. diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993206"}
{"pmid": "20993207", "title": "Isolation of virus of lymphogranuloma venereum from blood and spinal fluid of a human being.", "content": "Isolation of virus of lymphogranuloma venereum from blood and spinal fluid of a human being.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993207"}
{"pmid": "20993208", "title": "Effect of diet on the response of chicks to folic acid.", "content": "Effect of diet on the response of chicks to folic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993208"}
{"pmid": "20993209", "title": "Effect of some of the B complex vitamins upon chick tissue cultures.", "content": "Effect of some of the B complex vitamins upon chick tissue cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993209"}
{"pmid": "20993210", "title": "Production of atheromatosis in the aorta of the chicken by administration of diethylstilbestrol.", "content": "Production of atheromatosis in the aorta of the chicken by administration of diethylstilbestrol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993210"}
{"pmid": "20993211", "title": "A transitory decrease in glucose tolerance following experimental lesions in the central nervous system.", "content": "A transitory decrease in glucose tolerance following experimental lesions in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993211"}
{"pmid": "20993212", "title": "Adaptation of Colorado tick fever virus to mouse and developing chick embryo.", "content": "Adaptation of Colorado tick fever virus to mouse and developing chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993212"}
{"pmid": "20993213", "title": "A toxic principle from progestational endometrium and placenta.", "content": "A toxic principle from progestational endometrium and placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993213"}
{"pmid": "20993214", "title": "Liver necrosis in mice following injection of toxic extracts of progestational endometrium and of placenta.", "content": "Liver necrosis in mice following injection of toxic extracts of progestational endometrium and of placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993214"}
{"pmid": "20993215", "title": "Influence of dietary iodine on susceptibility of rats to alpha naphthylthiourea poisoning.", "content": "Influence of dietary iodine on susceptibility of rats to alpha naphthylthiourea poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993215"}
{"pmid": "20993239", "title": "Penicillin in the treatment of acute osteomyelitis; with case reports.", "content": "Penicillin in the treatment of acute osteomyelitis; with case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993239"}
{"pmid": "20993240", "title": "Yaws; treatment with penicillin.", "content": "Yaws; treatment with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993240"}
{"pmid": "20993241", "title": "Coccidioidomycosis treated with penicillin; case report.", "content": "Coccidioidomycosis treated with penicillin; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993241"}
{"pmid": "20993242", "title": "Coccidioidomycosis.", "content": "Coccidioidomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993242"}
{"pmid": "20993243", "title": "Spontaneous pneumoperitoneum without peritonitis and without demonstrable cause.", "content": "Spontaneous pneumoperitoneum without peritonitis and without demonstrable cause.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993243"}
{"pmid": "20993244", "title": "Intermuscular lipoma of the thigh, with roentgenologic findings.", "content": "Intermuscular lipoma of the thigh, with roentgenologic findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993244"}
{"pmid": "20993245", "title": "Still's disease (atrophic arthritis, atrophic rheumatoid arthritis or infectious rheumatoid arthritis).", "content": "Still's disease (atrophic arthritis, atrophic rheumatoid arthritis or infectious rheumatoid arthritis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993245"}
{"pmid": "20993247", "title": "The activity of another L. casei factor in macrocytic anemia.", "content": "The activity of another L. casei factor in macrocytic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993247"}
{"pmid": "20993246", "title": "A comparison of quinine and quinacrine in the treatment of the clinical attacks of vivax malaria.", "content": "A comparison of quinine and quinacrine in the treatment of the clinical attacks of vivax malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993246"}
{"pmid": "20993248", "title": "Respiratory emergencies in infants and children.", "content": "Respiratory emergencies in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993248"}
{"pmid": "20993249", "title": "Intravenous anesthesia in anorectal surgery.", "content": "Intravenous anesthesia in anorectal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993249"}
{"pmid": "20993250", "title": "Review of spinal pentothal anesthesia.", "content": "Review of spinal pentothal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993250"}
{"pmid": "20993251", "title": "Penicillin in acute pelvic inflammatory diseases (non-venereal).", "content": "Penicillin in acute pelvic inflammatory diseases (non-venereal).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993251"}
{"pmid": "20993252", "title": "The effect of caffeine on gastric secretion.", "content": "The effect of caffeine on gastric secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993252"}
{"pmid": "20993253", "title": "Privine sensitivity; a report of eight cases.", "content": "Privine sensitivity; a report of eight cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993253"}
{"pmid": "20993254", "title": "A realistic approach to medical education in the Southwest.", "content": "A realistic approach to medical education in the Southwest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993254"}
{"pmid": "20993255", "title": "Tetanus.", "content": "Tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993255"}
{"pmid": "20993256", "title": "Peritonitis, and its treatment.", "content": "Peritonitis, and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993256"}
{"pmid": "20993264", "title": "Disfigurements of the face.", "content": "Disfigurements of the face.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993264"}
{"pmid": "20993263", "title": "The Rh factor; is it important.", "content": "The Rh factor; is it important.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993263"}
{"pmid": "20993265", "title": "Some precautions in the administration of sulfa drugs.", "content": "Some precautions in the administration of sulfa drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993265"}
{"pmid": "20993266", "title": "The importance of cerebrospinal fluid examination in syphilis.", "content": "The importance of cerebrospinal fluid examination in syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993266"}
{"pmid": "20993267", "title": "Pulmonary actinomycosis due to Actinomyces asteroides.", "content": "Pulmonary actinomycosis due to Actinomyces asteroides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993267"}
{"pmid": "20993268", "title": "Use of defibrinated human blood for culturing the tubercle bacillus.", "content": "Use of defibrinated human blood for culturing the tubercle bacillus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993268"}
{"pmid": "20993269", "title": "Surgical lesions of the greater omentum.", "content": "Surgical lesions of the greater omentum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993269"}
{"pmid": "20993270", "title": "Progress and increased activities of Virginia Cancer Foundation.", "content": "Progress and increased activities of Virginia Cancer Foundation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993270"}
{"pmid": "20993271", "title": "The doctor's wife.", "content": "The doctor's wife.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993271"}
{"pmid": "20993273", "title": "Die Zuckerkrankheit (diabetes mellitus).", "content": "Die Zuckerkrankheit (diabetes mellitus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993273"}
{"pmid": "20993272", "title": "Analysis of current legislative proposals to nationalize medicine in the United States.", "content": "Analysis of current legislative proposals to nationalize medicine in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993272"}
{"pmid": "20993275", "title": "The anemias associated with nutritional disorders.", "content": "The anemias associated with nutritional disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993275"}
{"pmid": "20993277", "title": "The role of the general practitioner in tuberculosis control.", "content": "The role of the general practitioner in tuberculosis control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993277"}
{"pmid": "20993276", "title": "Twins, one macerated, retained: the other, normal delivery at term; case report.", "content": "Twins, one macerated, retained: the other, normal delivery at term; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993276"}
{"pmid": "20993278", "title": "Surgical approach to the posterosuperior mediastinum.", "content": "Surgical approach to the posterosuperior mediastinum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993278"}
{"pmid": "20993279", "title": "HISTORY of the Association of Military Clinical Psychologists.", "content": "HISTORY of the Association of Military Clinical Psychologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993279"}
{"pmid": "20993280", "title": "Contribution of the clinical psychologist in the rehabilitation of general prisoners.", "content": "Contribution of the clinical psychologist in the rehabilitation of general prisoners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993280"}
{"pmid": "20993281", "title": "Functions of a clinical psychologist working with aphasic patients.", "content": "Functions of a clinical psychologist working with aphasic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993281"}
{"pmid": "20993282", "title": "Current activities of the Clinical Psychology Branch.", "content": "Current activities of the Clinical Psychology Branch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993282"}
{"pmid": "20993283", "title": "Current activities of psychologist in the Adjutant General's Office.", "content": "Current activities of psychologist in the Adjutant General's Office.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993283"}
{"pmid": "20993284", "title": "Planning for psychological services in the new Army.", "content": "Planning for psychological services in the new Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993284"}
{"pmid": "20993285", "title": "RESEARCH on personality testing.", "content": "RESEARCH on personality testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993285"}
{"pmid": "20993286", "title": "Some observations on clinical method in psychology.", "content": "Some observations on clinical method in psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993286"}
{"pmid": "20993287", "title": "On the meaning of intelligence.", "content": "On the meaning of intelligence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993287"}
{"pmid": "20993288", "title": "Contributions of the clinical psychologist to Army training programs.", "content": "Contributions of the clinical psychologist to Army training programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993288"}
{"pmid": "20993289", "title": "Visual aids in lectures on adjustment.", "content": "Visual aids in lectures on adjustment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993289"}
{"pmid": "20993290", "title": "Book of surgeon's stewards.", "content": "Book of surgeon's stewards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993290"}
{"pmid": "20993292", "title": "Notes on the military prisoner.", "content": "Notes on the military prisoner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993292"}
{"pmid": "20993291", "title": "Venereal disease control in a rural area in war time.", "content": "Venereal disease control in a rural area in war time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993291"}
{"pmid": "20993293", "title": "Temporary facial prostheses as an aid in the treatment of war injuries.", "content": "Temporary facial prostheses as an aid in the treatment of war injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993293"}
{"pmid": "20993294", "title": "Unexplained amblyopia as a military problem.", "content": "Unexplained amblyopia as a military problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993294"}
{"pmid": "20993295", "title": "Complications of scabies.", "content": "Complications of scabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993295"}
{"pmid": "20993296", "title": "Acute injuries of the first metacarpal in military personnel.", "content": "Acute injuries of the first metacarpal in military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993296"}
{"pmid": "20993297", "title": "An aid to the handling of patients in hip spica casts; report of a case.", "content": "An aid to the handling of patients in hip spica casts; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993297"}
{"pmid": "20993298", "title": "An improvised oxygen tent.", "content": "An improvised oxygen tent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993298"}
{"pmid": "20993299", "title": "Field construction of an improved slit lamp and chin rest.", "content": "Field construction of an improved slit lamp and chin rest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993299"}
{"pmid": "20993300", "title": "The first decade of the Bureau of Medicine and Surgery.", "content": "The first decade of the Bureau of Medicine and Surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993300"}
{"pmid": "20993301", "title": "FUNCTION of the Veterans' Administration.", "content": "FUNCTION of the Veterans' Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993301"}
{"pmid": "20993302", "title": "The Naval Medical School in 1946.", "content": "The Naval Medical School in 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993302"}
{"pmid": "20993303", "title": "A rapid method for determining methyl alcohol in the blood and body fluids.", "content": "A rapid method for determining methyl alcohol in the blood and body fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993303"}
{"pmid": "20993304", "title": "Injection of iodized oil as an aid to closure of draining sinuses.", "content": "Injection of iodized oil as an aid to closure of draining sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993304"}
{"pmid": "20993305", "title": "Tropical acne.", "content": "Tropical acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993305"}
{"pmid": "20993306", "title": "Artificial teeth in Navy dental prosthetics.", "content": "Artificial teeth in Navy dental prosthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993306"}
{"pmid": "20993307", "title": "Bronchiectasis; a clinical analysis of 39 cases.", "content": "Bronchiectasis; a clinical analysis of 39 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993307"}
{"pmid": "20993308", "title": "Giardiasis; question of pathogenicity.", "content": "Giardiasis; question of pathogenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993308"}
{"pmid": "20993309", "title": "Neuralgic reflex from impacted lower third molar.", "content": "Neuralgic reflex from impacted lower third molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993309"}
{"pmid": "20993310", "title": "The specific gravity of healthy men; a report of 835 cases.", "content": "The specific gravity of healthy men; a report of 835 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993310"}
{"pmid": "20993311", "title": "Pneumococcal vulvitis and vaginitis; report of a case.", "content": "Pneumococcal vulvitis and vaginitis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993311"}
{"pmid": "20993312", "title": "Prosthetic restoration following gunshot injury of maxilla.", "content": "Prosthetic restoration following gunshot injury of maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993312"}
{"pmid": "20993313", "title": "A suggested modification of the Bogen procedure for determination of alcohol in body fluids.", "content": "A suggested modification of the Bogen procedure for determination of alcohol in body fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993313"}
{"pmid": "20993314", "title": "Some problems encountered in dental prosthetics for recruits.", "content": "Some problems encountered in dental prosthetics for recruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993314"}
{"pmid": "20993315", "title": "External otitis in the tropics.", "content": "External otitis in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993315"}
{"pmid": "20993316", "title": "Efficacy of penicillin ointments.", "content": "Efficacy of penicillin ointments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993316"}
{"pmid": "20993317", "title": "Intradermal tests with dirofilaria immitis antigen as a diagnostic aid in human filariasis.", "content": "Intradermal tests with dirofilaria immitis antigen as a diagnostic aid in human filariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993317"}
{"pmid": "20993319", "title": "Underwater confinement; report of three cases.", "content": "Underwater confinement; report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993319"}
{"pmid": "20993318", "title": "Occlusal balance in full denture prosthesis.", "content": "Occlusal balance in full denture prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993318"}
{"pmid": "20993320", "title": "Massive fat embolism following fracture of the femur; report of four fatal cases with necropsy findings.", "content": "Massive fat embolism following fracture of the femur; report of four fatal cases with necropsy findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993320"}
{"pmid": "20993321", "title": "Danger of finger rings.", "content": "Danger of finger rings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993321"}
{"pmid": "20993322", "title": "The Marcus-Gunn syndrome; report of a case.", "content": "The Marcus-Gunn syndrome; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993322"}
{"pmid": "20993323", "title": "Secondary syphilis of the tonsils.", "content": "Secondary syphilis of the tonsils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993323"}
{"pmid": "20993324", "title": "Amelogenesis imperfecta; report of a case.", "content": "Amelogenesis imperfecta; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993324"}
{"pmid": "20993325", "title": "A pneumatic splint for the leg.", "content": "A pneumatic splint for the leg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993325"}
{"pmid": "20993326", "title": "Plasma, a nutrient dusting powder; used to nullify the rubber cement used in connection with the Padgett dermatome.", "content": "Plasma, a nutrient dusting powder; used to nullify the rubber cement used in connection with the Padgett dermatome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993326"}
{"pmid": "20993327", "title": "An improvised spray rig for the dispersal of DDT solutions by airplane.", "content": "An improvised spray rig for the dispersal of DDT solutions by airplane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993327"}
{"pmid": "20993328", "title": "Rodent control, U.S. Navy, Pacific Ocean areas, World War II.", "content": "Rodent control, U.S. Navy, Pacific Ocean areas, World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993328"}
{"pmid": "20993329", "title": "Teamwork in research.", "content": "Teamwork in research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993329"}
{"pmid": "20993330", "title": "Monochromatic light absorption by normal chicken erythrocytes.", "content": "Monochromatic light absorption by normal chicken erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993330"}
{"pmid": "20993331", "title": "The Johns Hopkins University and the atomic bomb.", "content": "The Johns Hopkins University and the atomic bomb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993331"}
{"pmid": "20993332", "title": "Nitroglycerine and guncotton, a double centenary.", "content": "Nitroglycerine and guncotton, a double centenary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993332"}
{"pmid": "20993333", "title": "Nutritive values of foods and condiments.", "content": "Nutritive values of foods and condiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993333"}
{"pmid": "20993334", "title": "Reactions of organic halides in solution.", "content": "Reactions of organic halides in solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993334"}
{"pmid": "20993335", "title": "Differentiation between glucose, galactose and mannose by a colour reaction.", "content": "Differentiation between glucose, galactose and mannose by a colour reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993335"}
{"pmid": "20993336", "title": "Use of synthetic resins in the estimation of trace elements.", "content": "Use of synthetic resins in the estimation of trace elements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993336"}
{"pmid": "20993337", "title": "Anti-oxygen stabilization of bilirubin in alkaline medium by ascorbic acid and cysteine.", "content": "Anti-oxygen stabilization of bilirubin in alkaline medium by ascorbic acid and cysteine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993337"}
{"pmid": "20993338", "title": "Carcinogenic substance from human cancer.", "content": "Carcinogenic substance from human cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993338"}
{"pmid": "20993339", "title": "Co-aminopherase, co-decarboxylase and pyridoxal.", "content": "Co-aminopherase, co-decarboxylase and pyridoxal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993339"}
{"pmid": "20993340", "title": "LIBRARIES and research needs.", "content": "LIBRARIES and research needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993340"}
{"pmid": "20993341", "title": "Civilization and the pursuit of knowledge.", "content": "Civilization and the pursuit of knowledge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993341"}
{"pmid": "20993342", "title": "Vaccinia haemagglutinin.", "content": "Vaccinia haemagglutinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993342"}
{"pmid": "20993343", "title": "Establishment of cytochemical techniques.", "content": "Establishment of cytochemical techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993343"}
{"pmid": "20993344", "title": "A new acarine parasite of bees.", "content": "A new acarine parasite of bees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993344"}
{"pmid": "20993345", "title": "A new method for the study of renal tubular excretion in birds.", "content": "A new method for the study of renal tubular excretion in birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993345"}
{"pmid": "20993346", "title": "An anti-tick salve for lambs.", "content": "An anti-tick salve for lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993346"}
{"pmid": "20993347", "title": "Effect of pH in the dye titration of vitamin C in certain plant materials.", "content": "Effect of pH in the dye titration of vitamin C in certain plant materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993347"}
{"pmid": "20993348", "title": "Molecular rotation in keratin.", "content": "Molecular rotation in keratin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993348"}
{"pmid": "20993349", "title": "Supersonic cries of bats.", "content": "Supersonic cries of bats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993349"}
{"pmid": "20993350", "title": "High mutant gene frequencies in a population of Drosophila immigrans.", "content": "High mutant gene frequencies in a population of Drosophila immigrans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993350"}
{"pmid": "20993351", "title": "Differential stains of insect tissues.", "content": "Differential stains of insect tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993351"}
{"pmid": "20993352", "title": "We get the insects or they get us.", "content": "We get the insects or they get us.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993352"}
{"pmid": "20993353", "title": "KEEP cool. [Refrigeration].", "content": "KEEP cool. [Refrigeration].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993353"}
{"pmid": "20993354", "title": "A BREAK for the drowning.", "content": "A BREAK for the drowning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993354"}
{"pmid": "20993355", "title": "MEAT-eating plants.", "content": "MEAT-eating plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993355"}
{"pmid": "20993356", "title": "GERM counter.", "content": "GERM counter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993356"}
{"pmid": "20993357", "title": "HEALING of broken bones in dog or man is speeded by a comfortable device.", "content": "HEALING of broken bones in dog or man is speeded by a comfortable device.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993357"}
{"pmid": "20993358", "title": "Science and incentives in Russia.", "content": "Science and incentives in Russia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993358"}
{"pmid": "20993359", "title": "The responsibilities of health-physics.", "content": "The responsibilities of health-physics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993359"}
{"pmid": "20993360", "title": "Does the sting ray strike and poison fishes?", "content": "Does the sting ray strike and poison fishes?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993360"}
{"pmid": "20993361", "title": "Riboflavin as a factor in the adequacy of the American food supply.", "content": "Riboflavin as a factor in the adequacy of the American food supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993361"}
{"pmid": "20993362", "title": "The action of insecticides.", "content": "The action of insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993362"}
{"pmid": "20993363", "title": "Observations in a case of muscular dystrophy with reference to diagnostic significance.", "content": "Observations in a case of muscular dystrophy with reference to diagnostic significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993363"}
{"pmid": "20993364", "title": "Effects of 1 (-) glutamic acid and other agents on experimental seizures.", "content": "Effects of 1 (-) glutamic acid and other agents on experimental seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993364"}
{"pmid": "20993365", "title": "Sensation of electric shock following head injury.", "content": "Sensation of electric shock following head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993365"}
{"pmid": "20993366", "title": "Neuropsychiatric observation on tsutsugamushi fever (scrub typhus).", "content": "Neuropsychiatric observation on tsutsugamushi fever (scrub typhus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993366"}
{"pmid": "20993367", "title": "Permeability of blood-spinal fluid barrier in infants and in normal and syphilitic adults.", "content": "Permeability of blood-spinal fluid barrier in infants and in normal and syphilitic adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993367"}
{"pmid": "20993368", "title": "Use of quantitative parasite inoculation doses in Plasmodium vivax malaria therapy.", "content": "Use of quantitative parasite inoculation doses in Plasmodium vivax malaria therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993368"}
{"pmid": "20993369", "title": "Resistance to insulin in mentally disturbed soldiers.", "content": "Resistance to insulin in mentally disturbed soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993369"}
{"pmid": "20993370", "title": "Histopathologic changes in cerebral malaria and their relation to psychotic sequels.", "content": "Histopathologic changes in cerebral malaria and their relation to psychotic sequels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993370"}
{"pmid": "20993371", "title": "Modern concepts of the convulsive state.", "content": "Modern concepts of the convulsive state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993371"}
{"pmid": "20993372", "title": "Utilization of a therapy group in teaching psychotherapy.", "content": "Utilization of a therapy group in teaching psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993372"}
{"pmid": "20993373", "title": "The mentally diseased patient as an individual.", "content": "The mentally diseased patient as an individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993373"}
{"pmid": "20993374", "title": "Narcosynthesis of the civilian neurosis.", "content": "Narcosynthesis of the civilian neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993374"}
{"pmid": "20993375", "title": "Penicillin therapy for spina bifida.", "content": "Penicillin therapy for spina bifida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993375"}
{"pmid": "20993376", "title": "Disseminated, diffuse and transitional demyelination of the central nervous system.", "content": "Disseminated, diffuse and transitional demyelination of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993376"}
{"pmid": "20993377", "title": "Cerebral vascular occlusions in young adults.", "content": "Cerebral vascular occlusions in young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993377"}
{"pmid": "20993378", "title": "A clinical study of postdiphtheritic polyneuritis.", "content": "A clinical study of postdiphtheritic polyneuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993378"}
{"pmid": "20993379", "title": "The enuretic soldier in an AAF basic training center; a study of 172 cases.", "content": "The enuretic soldier in an AAF basic training center; a study of 172 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993379"}
{"pmid": "20993380", "title": "Personality reaction to crime and disease.", "content": "Personality reaction to crime and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993380"}
{"pmid": "20993381", "title": "Huntington's chorea; report of a case.", "content": "Huntington's chorea; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993381"}
{"pmid": "20993382", "title": "Two cases of parenchymatous cerebellar degeneration.", "content": "Two cases of parenchymatous cerebellar degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993382"}
{"pmid": "20993383", "title": "A case of ophthalmoplegic migraine, and a theory for its production.", "content": "A case of ophthalmoplegic migraine, and a theory for its production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993383"}
{"pmid": "20993384", "title": "Case of progressive nuclear ophthlamoplegia, possibly on a vitamin deficiency basis.", "content": "Case of progressive nuclear ophthlamoplegia, possibly on a vitamin deficiency basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993384"}
{"pmid": "20993385", "title": "Two cases illustrating the treatment of torticollis.", "content": "Two cases illustrating the treatment of torticollis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993385"}
{"pmid": "20993386", "title": "Re-examination of the factors causing mass spasms after transection in the cord in man.", "content": "Re-examination of the factors causing mass spasms after transection in the cord in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993386"}
{"pmid": "20993387", "title": "Lymphocytosis after electrical convulsion.", "content": "Lymphocytosis after electrical convulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993387"}
{"pmid": "20993388", "title": "The relation between the electroencephalogram and muscle action potentials in certain convulsive states.", "content": "The relation between the electroencephalogram and muscle action potentials in certain convulsive states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993388"}
{"pmid": "20993389", "title": "The disorganization of behaviour in fatigue.", "content": "The disorganization of behaviour in fatigue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993389"}
{"pmid": "20993390", "title": "Some observations on the visual fields in hydrocephalus.", "content": "Some observations on the visual fields in hydrocephalus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993390"}
{"pmid": "20993391", "title": "Schizencephalies; a study of the congenital clefts in the cerebral mantle; clefts with hydrocephalus and lips separated.", "content": "Schizencephalies; a study of the congenital clefts in the cerebral mantle; clefts with hydrocephalus and lips separated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993391"}
{"pmid": "20993392", "title": "The motor cortex in amyotonia congenita.", "content": "The motor cortex in amyotonia congenita.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993392"}
{"pmid": "20993393", "title": "Subarachnoid and ventricular implants in ependymal and other gliomas.", "content": "Subarachnoid and ventricular implants in ependymal and other gliomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993393"}
{"pmid": "20993394", "title": "A cortical anomaly with some porencephalic features.", "content": "A cortical anomaly with some porencephalic features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993394"}
{"pmid": "20993396", "title": "Complete and permanent elimination of the hypothalamic thermogenic mechanism without affecting the adequacy of the heat loss mechanism.", "content": "Complete and permanent elimination of the hypothalamic thermogenic mechanism without affecting the adequacy of the heat loss mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993396"}
{"pmid": "20993395", "title": "Circumscribed arachnoidal sarcoma of cerebellum; report of a case.", "content": "Circumscribed arachnoidal sarcoma of cerebellum; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993395"}
{"pmid": "20993397", "title": "Porencephaly; a clinicopathologic study.", "content": "Porencephaly; a clinicopathologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993397"}
{"pmid": "20993398", "title": "The diary of Vaslav Nijinsky; a pathographical study of a case of schizophrenia.", "content": "The diary of Vaslav Nijinsky; a pathographical study of a case of schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993398"}
{"pmid": "20993399", "title": "The approach to reality.", "content": "The approach to reality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993399"}
{"pmid": "20993400", "title": "The extension of basic scientific laws to psychoanalysis and to psychology.", "content": "The extension of basic scientific laws to psychoanalysis and to psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993400"}
{"pmid": "20993401", "title": "Teiresias and other seers.", "content": "Teiresias and other seers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993401"}
{"pmid": "20993402", "title": "The analysis of a dream occurring during a migraine attack.", "content": "The analysis of a dream occurring during a migraine attack.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993402"}
{"pmid": "20993403", "title": "An ill bred child.", "content": "An ill bred child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993403"}
{"pmid": "20993404", "title": "Oedipus and beyond.", "content": "Oedipus and beyond.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993404"}
{"pmid": "20993405", "title": "On a particular form of resistance in the transference; a clinical communication.", "content": "On a particular form of resistance in the transference; a clinical communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993405"}
{"pmid": "20993406", "title": "Dental anxiety; fear of going to the dentist.", "content": "Dental anxiety; fear of going to the dentist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993406"}
{"pmid": "20993413", "title": "Technique of partial thyroidectomy.", "content": "Technique of partial thyroidectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993413"}
{"pmid": "20993414", "title": "Control of infectious diseases; isolation.", "content": "Control of infectious diseases; isolation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993414"}
{"pmid": "20993415", "title": "Failures in teaching.", "content": "Failures in teaching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993415"}
{"pmid": "20993416", "title": "Great mental hospital in Vienna.", "content": "Great mental hospital in Vienna.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993416"}
{"pmid": "20993417", "title": "Step by step application of a spica bandage to the hip.", "content": "Step by step application of a spica bandage to the hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993417"}
{"pmid": "20993418", "title": "Recent studies in fibrositis.", "content": "Recent studies in fibrositis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993418"}
{"pmid": "20993419", "title": "The relationship between relaxation and easy childbirth.", "content": "The relationship between relaxation and easy childbirth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993419"}
{"pmid": "20993420", "title": "Surgery of the sympathetic nervous system.", "content": "Surgery of the sympathetic nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993420"}
{"pmid": "20993421", "title": "CHEMICAL warfare; against tuberculosis.", "content": "CHEMICAL warfare; against tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993421"}
{"pmid": "20993422", "title": "Houses and housing.", "content": "Houses and housing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993422"}
{"pmid": "20993423", "title": "THE DEFECTIVE mind.", "content": "THE DEFECTIVE mind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993423"}
{"pmid": "20993424", "title": "Effects of tropical diseases on the ex-service man.", "content": "Effects of tropical diseases on the ex-service man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993424"}
{"pmid": "20993425", "title": "Curbing the clot that kills.", "content": "Curbing the clot that kills.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993425"}
{"pmid": "20993427", "title": "Painless childbirth.", "content": "Painless childbirth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993427"}
{"pmid": "20993428", "title": "Use of diisopropyl fluorophosphate (PFP) in treatment of glaucoma.", "content": "Use of diisopropyl fluorophosphate (PFP) in treatment of glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993428"}
{"pmid": "20993429", "title": "Effect of diisopropyl fluorophosphate (PFP) on the normal eye.", "content": "Effect of diisopropyl fluorophosphate (PFP) on the normal eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993429"}
{"pmid": "20993430", "title": "Visual disturbances associated with head injuries.", "content": "Visual disturbances associated with head injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993430"}
{"pmid": "20993431", "title": "Plastic repair of deformities of the socket and minor defects about the orbit.", "content": "Plastic repair of deformities of the socket and minor defects about the orbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993431"}
{"pmid": "20993432", "title": "Influence of local antiseptics on regeneration of corneal epithelium of rabbits.", "content": "Influence of local antiseptics on regeneration of corneal epithelium of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993432"}
{"pmid": "20993434", "title": "Conservation of vision [Book Review].", "content": "Conservation of vision [Book Review].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993434"}
{"pmid": "20993433", "title": "Hereditary disk-shaped (ring) cataract; report on a family, with microscopic examination of an eye.", "content": "Hereditary disk-shaped (ring) cataract; report on a family, with microscopic examination of an eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993433"}
{"pmid": "20993435", "title": "Amblyopia due to dietary deficiency; report of eight cases.", "content": "Amblyopia due to dietary deficiency; report of eight cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993435"}
{"pmid": "20993436", "title": "Method of closing the cataract incision by sliding a large conjunctival flap from above down over a corneoscleral suture.", "content": "Method of closing the cataract incision by sliding a large conjunctival flap from above down over a corneoscleral suture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993436"}
{"pmid": "20993437", "title": "Arterial hypertension.", "content": "Arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993437"}
{"pmid": "20993438", "title": "Sight development.", "content": "Sight development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993438"}
{"pmid": "20993439", "title": "Eye care increases earnings of electric solderers.", "content": "Eye care increases earnings of electric solderers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993439"}
{"pmid": "20993448", "title": "Physical education for low vision classes.", "content": "Physical education for low vision classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993448"}
{"pmid": "20993449", "title": "A brief review of rheumatic fever; the role of tonsillitis in its etiology.", "content": "A brief review of rheumatic fever; the role of tonsillitis in its etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993449"}
{"pmid": "20993450", "title": "Individual differences in hearing for speech.", "content": "Individual differences in hearing for speech.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993450"}
{"pmid": "20993451", "title": "Frontal sinus drainage.", "content": "Frontal sinus drainage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993451"}
{"pmid": "20993452", "title": "Development of the aquaeductus cochleae and its contained periotic duct and cochlear vein in human embryos.", "content": "Development of the aquaeductus cochleae and its contained periotic duct and cochlear vein in human embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993452"}
{"pmid": "20993453", "title": "The influence of the sulfonamides and anti-biotics on the future of otolaryngology.", "content": "The influence of the sulfonamides and anti-biotics on the future of otolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993453"}
{"pmid": "20993454", "title": "Nasal physiology in relation to the common cold.", "content": "Nasal physiology in relation to the common cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993454"}
{"pmid": "20993455", "title": "Malignant tumors of the maxillary sinus; an analysis of 47 fatalities.", "content": "Malignant tumors of the maxillary sinus; an analysis of 47 fatalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993455"}
{"pmid": "20993456", "title": "Adamantinoma of the maxillary sinus with a report of two cases.", "content": "Adamantinoma of the maxillary sinus with a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993456"}
{"pmid": "20993457", "title": "Schwannoma of the pharynx.", "content": "Schwannoma of the pharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993457"}
{"pmid": "20993458", "title": "Solitary extramedullary plasmocytoma.", "content": "Solitary extramedullary plasmocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993458"}
{"pmid": "20993459", "title": "Aerotitis media in submariners.", "content": "Aerotitis media in submariners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993459"}
{"pmid": "20993460", "title": "The problem of secondary frontal sinus surgery.", "content": "The problem of secondary frontal sinus surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993460"}
{"pmid": "20993461", "title": "Tinnitus aurium: observations on the effect of curare on loudness level.", "content": "Tinnitus aurium: observations on the effect of curare on loudness level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993461"}
{"pmid": "20993462", "title": "The external ear and drum membrane in otosclerosis.", "content": "The external ear and drum membrane in otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993462"}
{"pmid": "20993463", "title": "Tuning fork tests; a historical review.", "content": "Tuning fork tests; a historical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993463"}
{"pmid": "20993464", "title": "Contact ulcer of the larynx.", "content": "Contact ulcer of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993464"}
{"pmid": "20993465", "title": "Unilateral exophthalmos.", "content": "Unilateral exophthalmos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993465"}
{"pmid": "20993466", "title": "Neck infections.", "content": "Neck infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993466"}
{"pmid": "20993467", "title": "Sulfonamide toxicity; interpretation of laboratory findings.", "content": "Sulfonamide toxicity; interpretation of laboratory findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993467"}
{"pmid": "20993468", "title": "Surgical treatment of otosclerosis; a preliminary report on an improved fenestration technic.", "content": "Surgical treatment of otosclerosis; a preliminary report on an improved fenestration technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993468"}
{"pmid": "20993469", "title": "Late secondary tonsillar hemorrhage; studies of ascorbic acid.", "content": "Late secondary tonsillar hemorrhage; studies of ascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993469"}
{"pmid": "20993470", "title": "Treatment of tuberculosis of the larynx.", "content": "Treatment of tuberculosis of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993470"}
{"pmid": "20993471", "title": "Penicillin ear drops in the treatment of suppurative otitis media.", "content": "Penicillin ear drops in the treatment of suppurative otitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993471"}
{"pmid": "20993472", "title": "Hypertrophy of the masseter muscle.", "content": "Hypertrophy of the masseter muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993472"}
{"pmid": "20993473", "title": "Evaluation of benadryl as a therapeutic agent for vasomotor and allergic rhinitis.", "content": "Evaluation of benadryl as a therapeutic agent for vasomotor and allergic rhinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993473"}
{"pmid": "20993474", "title": "Treatment of chronic purulent otitis media with glycerite of hydrogen peroxide.", "content": "Treatment of chronic purulent otitis media with glycerite of hydrogen peroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993474"}
{"pmid": "20993475", "title": "Atresia of the external auditory canal occurring in military service; a report on the correction of this condition in ten cases.", "content": "Atresia of the external auditory canal occurring in military service; a report on the correction of this condition in ten cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993475"}
{"pmid": "20993476", "title": "Effect of zephiran chloride, tyrothricin, penicillin and streptomycin on ciliary action.", "content": "Effect of zephiran chloride, tyrothricin, penicillin and streptomycin on ciliary action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993476"}
{"pmid": "20993477", "title": "Removal of a tortilla from the esophagus.", "content": "Removal of a tortilla from the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993477"}
{"pmid": "20993478", "title": "Advances in the understanding of rhinologic and otologic conditions related to the nervous system; a critical survey of recent literature.", "content": "Advances in the understanding of rhinologic and otologic conditions related to the nervous system; a critical survey of recent literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993478"}
{"pmid": "20993479", "title": "The study of enzymes in tissue sections.", "content": "The study of enzymes in tissue sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993479"}
{"pmid": "20993480", "title": "Approaches to the study of edema and dehydration.", "content": "Approaches to the study of edema and dehydration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993480"}
{"pmid": "20993481", "title": "Metastatic cancer of the extrahepatic bile ducts producing jaundice.", "content": "Metastatic cancer of the extrahepatic bile ducts producing jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993481"}
{"pmid": "20993482", "title": "Investigations on the Rh property.", "content": "Investigations on the Rh property.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993482"}
{"pmid": "20993483", "title": "Improved egg yolk infusion for cultivation of Entamoeba histolytica and other intestinal protozoa.", "content": "Improved egg yolk infusion for cultivation of Entamoeba histolytica and other intestinal protozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993483"}
{"pmid": "20993484", "title": "Adenomyoepithelioma of sweat gland; report of a case.", "content": "Adenomyoepithelioma of sweat gland; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993484"}
{"pmid": "20993485", "title": "A note on the titration of Kline antigen.", "content": "A note on the titration of Kline antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993485"}
{"pmid": "20993486", "title": "Human necrobacillosis; with report of death in a sailor.", "content": "Human necrobacillosis; with report of death in a sailor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993486"}
{"pmid": "20993487", "title": "A note on genital fusospirochetosis.", "content": "A note on genital fusospirochetosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993487"}
{"pmid": "20993488", "title": "Confusion in typing of stored blood; an irregular isoagglutinogen.", "content": "Confusion in typing of stored blood; an irregular isoagglutinogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993488"}
{"pmid": "20993489", "title": "Local tissue reactivity (Shwartzman phenomenon) in the heart and the femoral artery of the rabbit.", "content": "Local tissue reactivity (Shwartzman phenomenon) in the heart and the femoral artery of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993489"}
{"pmid": "20993490", "title": "Chorionic gonadotropin in the diagnosis of testicular tumors.", "content": "Chorionic gonadotropin in the diagnosis of testicular tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993490"}
{"pmid": "20993491", "title": "Toxicity and detoxication of cinchophen; experimental studies.", "content": "Toxicity and detoxication of cinchophen; experimental studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993491"}
{"pmid": "20993492", "title": "Human strongyloidiasis with internal autoinfection.", "content": "Human strongyloidiasis with internal autoinfection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993492"}
{"pmid": "20993493", "title": "Tropical ulcer in Guatemala; pathologic, bacteriologic, mycologic and clinical aspects.", "content": "Tropical ulcer in Guatemala; pathologic, bacteriologic, mycologic and clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993493"}
{"pmid": "20993494", "title": "Ethylene glycol poisoning; with suggestions for its treatment as oxalate poisoning.", "content": "Ethylene glycol poisoning; with suggestions for its treatment as oxalate poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993494"}
{"pmid": "20993495", "title": "Etiologic concepts and pathologic aspects of ainhum.", "content": "Etiologic concepts and pathologic aspects of ainhum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993495"}
{"pmid": "20993496", "title": "Primary cystic tumor of the diaphragm.", "content": "Primary cystic tumor of the diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993496"}
{"pmid": "20993497", "title": "Development of sebaceous glands from intralobular ducts of the parotid gland.", "content": "Development of sebaceous glands from intralobular ducts of the parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993497"}
{"pmid": "20993498", "title": "Leiomyosarcoma involving the right ureter.", "content": "Leiomyosarcoma involving the right ureter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993498"}
{"pmid": "20993499", "title": "Parathyroid adenoma, with uremia due to calcification of the kidneys.", "content": "Parathyroid adenoma, with uremia due to calcification of the kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993499"}
{"pmid": "20993501", "title": "Laboratory methods and technical notes.", "content": "Laboratory methods and technical notes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993501"}
{"pmid": "20993500", "title": "Splenic hemangiosarcoma; a case with lymphatic and vascular metastases.", "content": "Splenic hemangiosarcoma; a case with lymphatic and vascular metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993500"}
{"pmid": "20993502", "title": "A hemoglobin stain for histologic use based on the cyanol-hemoglobin reaction.", "content": "A hemoglobin stain for histologic use based on the cyanol-hemoglobin reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993502"}
{"pmid": "20993521", "title": "Chondro-osteodystrophy, Morquio's disease; report of a case in a colored child.", "content": "Chondro-osteodystrophy, Morquio's disease; report of a case in a colored child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993521"}
{"pmid": "20993522", "title": "Air sterilization.", "content": "Air sterilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993522"}
{"pmid": "20993523", "title": "The immunizing effects of antitoxin.", "content": "The immunizing effects of antitoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993523"}
{"pmid": "20993524", "title": "Influence of venous congestion on spinal reflex centres.", "content": "Influence of venous congestion on spinal reflex centres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993524"}
{"pmid": "20993525", "title": "DIGITOXIN.", "content": "DIGITOXIN.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993525"}
{"pmid": "20993527", "title": "INDICATIONS for streptomycin.", "content": "INDICATIONS for streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993527"}
{"pmid": "20993526", "title": "Poultry medication and the pharmacist.", "content": "Poultry medication and the pharmacist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993526"}
{"pmid": "20993528", "title": "MEDICINE faces a crisis; socialisation plans in Great Britian and Australia.", "content": "MEDICINE faces a crisis; socialisation plans in Great Britian and Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993528"}
{"pmid": "20993529", "title": "Hemp.", "content": "Hemp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993529"}
{"pmid": "20993530", "title": "The horse radish.", "content": "The horse radish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993530"}
{"pmid": "20993531", "title": "MEDICINE in ancient Scandinavia; healing art in the Viking age.", "content": "MEDICINE in ancient Scandinavia; healing art in the Viking age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993531"}
{"pmid": "20993533", "title": "VICTORIAN College of Pharmacy.", "content": "VICTORIAN College of Pharmacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993533"}
{"pmid": "20993532", "title": "PHARMACEUTICAL service in New Guinea.", "content": "PHARMACEUTICAL service in New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993532"}
{"pmid": "20993535", "title": "The work of a hospital pharmacist.", "content": "The work of a hospital pharmacist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993535"}
{"pmid": "20993534", "title": "CURE for relapsing malaria?", "content": "CURE for relapsing malaria?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993534"}
{"pmid": "20993536", "title": "The mulberry in medicine and legend.", "content": "The mulberry in medicine and legend.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993536"}
{"pmid": "20993537", "title": "New methods for estimating the composition of fatty acid mixtures.", "content": "New methods for estimating the composition of fatty acid mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993537"}
{"pmid": "20993538", "title": "Synthetic resins and water softening.", "content": "Synthetic resins and water softening.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993538"}
{"pmid": "20993539", "title": "Hypochlorite mists for air disinfection.", "content": "Hypochlorite mists for air disinfection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993539"}
{"pmid": "20993545", "title": "Transposing Latin and English in the new U.S.P. and N.F.", "content": "Transposing Latin and English in the new U.S.P. and N.F.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993545"}
{"pmid": "20993547", "title": "Isolation of hexokinase from baker's yeast.", "content": "Isolation of hexokinase from baker's yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993547"}
{"pmid": "20993548", "title": "Crystalline hexokinase, heterophosphatase; method of isolation and properties.", "content": "Crystalline hexokinase, heterophosphatase; method of isolation and properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993548"}
{"pmid": "20993550", "title": "Culture conditions and the development of the photosynthetic mechanism; influence of light intensity on cellular characteristics of Chlorella.", "content": "Culture conditions and the development of the photosynthetic mechanism; influence of light intensity on cellular characteristics of Chlorella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993550"}
{"pmid": "20993551", "title": "Culture conditions and the development of the photosynthetic mechanism; influence of light intensity on photosynthetic characteristics of Chlorella.", "content": "Culture conditions and the development of the photosynthetic mechanism; influence of light intensity on photosynthetic characteristics of Chlorella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993551"}
{"pmid": "20993552", "title": "The penetration of vesicant vapors into human skin.", "content": "The penetration of vesicant vapors into human skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993552"}
{"pmid": "20993553", "title": "Chemotaxis in leukocytes.", "content": "Chemotaxis in leukocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993553"}
{"pmid": "20993554", "title": "The physiology of nervous systems of invertebrate animals.", "content": "The physiology of nervous systems of invertebrate animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993554"}
{"pmid": "20993555", "title": "The pharmacology of the veratrum alkaloids.", "content": "The pharmacology of the veratrum alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993555"}
{"pmid": "20993556", "title": "Arthropod nervous systems; a review of their structure and function.", "content": "Arthropod nervous systems; a review of their structure and function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993556"}
{"pmid": "20993557", "title": "A three-year experiment with combined diphtheria toxoid; pertussis vaccine.", "content": "A three-year experiment with combined diphtheria toxoid; pertussis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993557"}
{"pmid": "20993558", "title": "Future goals in public health nursing.", "content": "Future goals in public health nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993558"}
{"pmid": "20993559", "title": "Nutrition problems of preschool children.", "content": "Nutrition problems of preschool children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993559"}
{"pmid": "20993560", "title": "The efficiency of the red cell adsorption and elution method for the preparation of influenza vaccine.", "content": "The efficiency of the red cell adsorption and elution method for the preparation of influenza vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993560"}
{"pmid": "20993561", "title": "Public health nursing in the control of syphilis and gonorrhoea; cases which require special attention.", "content": "Public health nursing in the control of syphilis and gonorrhoea; cases which require special attention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993561"}
{"pmid": "20993562", "title": "Colorado selectees rejected because of tuberculosis.", "content": "Colorado selectees rejected because of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993562"}
{"pmid": "20993563", "title": "Seroresistance (Wassermann-fastness) in syphilis; a discussion for the patient.", "content": "Seroresistance (Wassermann-fastness) in syphilis; a discussion for the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993563"}
{"pmid": "20993564", "title": "How drinking water is made safe.", "content": "How drinking water is made safe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993564"}
{"pmid": "20993565", "title": "Heart disease.", "content": "Heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993565"}
{"pmid": "20993566", "title": "The spoiled child.", "content": "The spoiled child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993566"}
{"pmid": "20993567", "title": "Practical aspects of the Rh factor.", "content": "Practical aspects of the Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993567"}
{"pmid": "20993568", "title": "Tuberculosis and the veteran.", "content": "Tuberculosis and the veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993568"}
{"pmid": "20993569", "title": "Restaurant sanitation.", "content": "Restaurant sanitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993569"}
{"pmid": "20993570", "title": "EVOLUTION of the Rehabilitation Program in Massachusetts.", "content": "EVOLUTION of the Rehabilitation Program in Massachusetts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993570"}
{"pmid": "20993571", "title": "Looking backward and forward in tuberculosis control.", "content": "Looking backward and forward in tuberculosis control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993571"}
{"pmid": "20993572", "title": "Infant mortality in Chester.", "content": "Infant mortality in Chester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993572"}
{"pmid": "20993573", "title": "The Scottish Council for Health Education.", "content": "The Scottish Council for Health Education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993573"}
{"pmid": "20993574", "title": "Health centres and the National Health Service.", "content": "Health centres and the National Health Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993574"}
{"pmid": "20993575", "title": "Chemoprophylaxis in the control of bacterial infections.", "content": "Chemoprophylaxis in the control of bacterial infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993575"}
{"pmid": "20993576", "title": "The comparative mortality index.", "content": "The comparative mortality index.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993576"}
{"pmid": "20993577", "title": "The incidence of Weil's disease in Grimsby fish-workers.", "content": "The incidence of Weil's disease in Grimsby fish-workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993577"}
{"pmid": "20993578", "title": "A case of food poisoning in man probably caused by the consumption of a duck's egg (further report).", "content": "A case of food poisoning in man probably caused by the consumption of a duck's egg (further report).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993578"}
{"pmid": "20993579", "title": "A note on the preparation of tetrathionate broth.", "content": "A note on the preparation of tetrathionate broth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993579"}
{"pmid": "20993580", "title": "The organisation of medical work.", "content": "The organisation of medical work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993580"}
{"pmid": "20993581", "title": "From drainpipe to biological background [housing].", "content": "From drainpipe to biological background [housing].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993581"}
{"pmid": "20993586", "title": "The water supply in Frankfurt Germany, as found upon occupation by U.S. Forces and thereafter.", "content": "The water supply in Frankfurt Germany, as found upon occupation by U.S. Forces and thereafter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993586"}
{"pmid": "20993587", "title": "The determination of suspended solids with glass crucibles; a study comparing sintered glass crucibles and the standard Gooch filter.", "content": "The determination of suspended solids with glass crucibles; a study comparing sintered glass crucibles and the standard Gooch filter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993587"}
{"pmid": "20993589", "title": "Anomalous right subclavian artery originating on the left as the last branch of the aortic arch; report of a probable case diagnosed roentgenologically.", "content": "Anomalous right subclavian artery originating on the left as the last branch of the aortic arch; report of a probable case diagnosed roentgenologically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993589"}
{"pmid": "20993588", "title": "The roentgen diagnosis of double aortic arch and other anomalies of the great vessels.", "content": "The roentgen diagnosis of double aortic arch and other anomalies of the great vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993588"}
{"pmid": "20993590", "title": "Saccular aneurysm of the abdominal aorta; report of a case of eight years' duration.", "content": "Saccular aneurysm of the abdominal aorta; report of a case of eight years' duration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993590"}
{"pmid": "20993591", "title": "Hepatodiaphragmatic interposition of the colon with gastric hypertrophy; case report.", "content": "Hepatodiaphragmatic interposition of the colon with gastric hypertrophy; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993591"}
{"pmid": "20993592", "title": "Myelography in patients with ruptured cervical intervertebral discs.", "content": "Myelography in patients with ruptured cervical intervertebral discs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993592"}
{"pmid": "20993593", "title": "The phantom nucleus pulposus.", "content": "The phantom nucleus pulposus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993593"}
{"pmid": "20993584", "title": "Sanitation inspection with ultra-violet light.", "content": "Sanitation inspection with ultra-violet light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993584"}
{"pmid": "20993594", "title": "Roentgenographic preparations from gross anatomic sections.", "content": "Roentgenographic preparations from gross anatomic sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993594"}
{"pmid": "20993595", "title": "Aberrant pancreas.", "content": "Aberrant pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993595"}
{"pmid": "20993585", "title": "Sanitation in European displaced persons camps.", "content": "Sanitation in European displaced persons camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993585"}
{"pmid": "20993582", "title": "A demonstration in food and utensil sanitation at M. I. T.", "content": "A demonstration in food and utensil sanitation at M. I. T.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993582"}
{"pmid": "20993596", "title": "The pancreas and its relation to psoriasis, eczema and certain other diseases of the skin.", "content": "The pancreas and its relation to psoriasis, eczema and certain other diseases of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993596"}
{"pmid": "20993597", "title": "Tumor dosage and results in roentgen therapy of cancer of the breast.", "content": "Tumor dosage and results in roentgen therapy of cancer of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993597"}
{"pmid": "20993598", "title": "Primary malignant bone tumors; a review of cases seen in the Radiation Therapy Department of Bellevue Hospital.", "content": "Primary malignant bone tumors; a review of cases seen in the Radiation Therapy Department of Bellevue Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993598"}
{"pmid": "20993599", "title": "Recovery from radiation mutations of the genes.", "content": "Recovery from radiation mutations of the genes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993599"}
{"pmid": "20993583", "title": "Report on food handlers courses at Houston, Texas.", "content": "Report on food handlers courses at Houston, Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993583"}
{"pmid": "20993600", "title": "The medical use of radioactive iodine.", "content": "The medical use of radioactive iodine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993600"}
{"pmid": "20993602", "title": "The lateral projection in roentgenography of the sternoclavicular articulation.", "content": "The lateral projection in roentgenography of the sternoclavicular articulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993602"}
{"pmid": "20993601", "title": "The use of tannic acid in barium enemas.", "content": "The use of tannic acid in barium enemas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993601"}
{"pmid": "20993628", "title": "A letter; early postoperative ambulation.", "content": "A letter; early postoperative ambulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993628"}
{"pmid": "20993629", "title": "Conservative gynecology.", "content": "Conservative gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993629"}
{"pmid": "20993630", "title": "Boiled cartilage implants.", "content": "Boiled cartilage implants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993630"}
{"pmid": "20993631", "title": "Rupture of the lower lumbar intervertebral disks.", "content": "Rupture of the lower lumbar intervertebral disks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993631"}
{"pmid": "20993632", "title": "Advantages of the gridiron incision in the treatment of carbuncles.", "content": "Advantages of the gridiron incision in the treatment of carbuncles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993632"}
{"pmid": "20993633", "title": "Late repair of tendons in the hand.", "content": "Late repair of tendons in the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993633"}
{"pmid": "20993634", "title": "Splenectomy in familial hemolytic jaundice; study and cure of patient with normal erythrocyte fragility and other unusual features.", "content": "Splenectomy in familial hemolytic jaundice; study and cure of patient with normal erythrocyte fragility and other unusual features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993634"}
{"pmid": "20993635", "title": "Interstitial hernia.", "content": "Interstitial hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993635"}
{"pmid": "20993636", "title": "Incipient epiphyseolisthesis of the hip; its diagnosis and treatment.", "content": "Incipient epiphyseolisthesis of the hip; its diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993636"}
{"pmid": "20993637", "title": "Carcinoma of the stomach.", "content": "Carcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993637"}
{"pmid": "20993638", "title": "Skin dressings in the treatment of debrided wounds.", "content": "Skin dressings in the treatment of debrided wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993638"}
{"pmid": "20993639", "title": "Regional anesthesia; its advantages in emergency surgery of the extremities.", "content": "Regional anesthesia; its advantages in emergency surgery of the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993639"}
{"pmid": "20993640", "title": "Pilonidal cysts; treatment by marsupialization operation.", "content": "Pilonidal cysts; treatment by marsupialization operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993640"}
{"pmid": "20993641", "title": "Use of transversus abdominis in repair of indirect inguinal hernia.", "content": "Use of transversus abdominis in repair of indirect inguinal hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993641"}
{"pmid": "20993642", "title": "Ultraviolet blood irradiation in biliary disease; Knott method.", "content": "Ultraviolet blood irradiation in biliary disease; Knott method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993642"}
{"pmid": "20993643", "title": "Physiology of the nose and its relation to plastic surgery.", "content": "Physiology of the nose and its relation to plastic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993643"}
{"pmid": "20993644", "title": "Hemolytic streptococcus in wounds of rabbits; action of 5-nitro-2-furaldehyde semicarbazone.", "content": "Hemolytic streptococcus in wounds of rabbits; action of 5-nitro-2-furaldehyde semicarbazone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993644"}
{"pmid": "20993646", "title": "A method of pelvic measurement.", "content": "A method of pelvic measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993646"}
{"pmid": "20993645", "title": "New operation for dislocated septal cartilage.", "content": "New operation for dislocated septal cartilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993645"}
{"pmid": "20993647", "title": "Koroseal; a rubber substitute.", "content": "Koroseal; a rubber substitute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993647"}
{"pmid": "20993648", "title": "Indirect inguinal hernia; repair of the anatomically weak area.", "content": "Indirect inguinal hernia; repair of the anatomically weak area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993648"}
{"pmid": "20993649", "title": "Intra-abdominal placement of drugs; a simple method.", "content": "Intra-abdominal placement of drugs; a simple method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993649"}
{"pmid": "20993650", "title": "Abdominal type of ectopic pregnancy.", "content": "Abdominal type of ectopic pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993650"}
{"pmid": "20993651", "title": "Hernia pericardii.", "content": "Hernia pericardii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993651"}
{"pmid": "20993652", "title": "Spontaneous closure of rectourethral fistula following perineal prostatectomy.", "content": "Spontaneous closure of rectourethral fistula following perineal prostatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993652"}
{"pmid": "20993653", "title": "Retroperitoneal fibroma with calcification.", "content": "Retroperitoneal fibroma with calcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993653"}
{"pmid": "20993654", "title": "Arteriovenous aneurysm or fistula.", "content": "Arteriovenous aneurysm or fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993654"}
{"pmid": "20993655", "title": "Lymphosarcoma of the rectum; five-year cure following local removal.", "content": "Lymphosarcoma of the rectum; five-year cure following local removal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993655"}
{"pmid": "20993656", "title": "Total resection of the clavicle.", "content": "Total resection of the clavicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993656"}
{"pmid": "20993657", "title": "Aberrant pancreatic tissue in the gallbladder wall.", "content": "Aberrant pancreatic tissue in the gallbladder wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993657"}
{"pmid": "20993658", "title": "Trauma to the sesamoid bones of the thumb.", "content": "Trauma to the sesamoid bones of the thumb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993658"}
{"pmid": "20993659", "title": "Postpartum, bilateral cortical necrosis of the kidneys with recovery.", "content": "Postpartum, bilateral cortical necrosis of the kidneys with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993659"}
{"pmid": "20993660", "title": "Cholecystitis with perforation.", "content": "Cholecystitis with perforation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993660"}
{"pmid": "20993661", "title": "Removal of shell fragment from left ventricle of the heart; report of a case.", "content": "Removal of shell fragment from left ventricle of the heart; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993661"}
{"pmid": "20993662", "title": "Reconstructive otoplasty; further observations; utilization of tantalum wire mesh support.", "content": "Reconstructive otoplasty; further observations; utilization of tantalum wire mesh support.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993662"}
{"pmid": "20993663", "title": "Blocking of the splan chnic nerves and the first lumbar sympathetic ganglion; technic, accidents and clinical indications.", "content": "Blocking of the splan chnic nerves and the first lumbar sympathetic ganglion; technic, accidents and clinical indications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993663"}
{"pmid": "20993664", "title": "Pulmonary suck and blow as a respiratory analeptic; interdependence of cardiac massage and suck and blow resuscitation.", "content": "Pulmonary suck and blow as a respiratory analeptic; interdependence of cardiac massage and suck and blow resuscitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993664"}
{"pmid": "20993665", "title": "War wounds of arteries.", "content": "War wounds of arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993665"}
{"pmid": "20993666", "title": "Glomus tumors, angioneuromyomas; a clinical and pathologic report of an unusual case.", "content": "Glomus tumors, angioneuromyomas; a clinical and pathologic report of an unusual case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993666"}
{"pmid": "20993667", "title": "Migratory polyphlebitis.", "content": "Migratory polyphlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993667"}
{"pmid": "20993668", "title": "The fate of preserved heterogeneous grafts of fascia when transplanted into living human tissues.", "content": "The fate of preserved heterogeneous grafts of fascia when transplanted into living human tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993668"}
{"pmid": "20993669", "title": "Peritonitis of appendiceal origin treated with massive doses of penicillin; report of 50 cases.", "content": "Peritonitis of appendiceal origin treated with massive doses of penicillin; report of 50 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993669"}
{"pmid": "20993670", "title": "Torsion of the spermatic cord.", "content": "Torsion of the spermatic cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993670"}
{"pmid": "20993671", "title": "Experimental study on liver function tests.", "content": "Experimental study on liver function tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993671"}
{"pmid": "20993672", "title": "Surgical treatment of pancreatic cysts.", "content": "Surgical treatment of pancreatic cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993672"}
{"pmid": "20993673", "title": "Severe burns: clinical findings with a simplified plan of early treatment.", "content": "Severe burns: clinical findings with a simplified plan of early treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993673"}
{"pmid": "20993674", "title": "Technique for the repair of postoperative abdominal hernias.", "content": "Technique for the repair of postoperative abdominal hernias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993674"}
{"pmid": "20993675", "title": "One stage tubed abdominal flaps; single pedicle tubes.", "content": "One stage tubed abdominal flaps; single pedicle tubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993675"}
{"pmid": "20993676", "title": "The effects of certain drugs on the sphincter of Oddi.", "content": "The effects of certain drugs on the sphincter of Oddi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993676"}
{"pmid": "20993677", "title": "Liposarcoma of the female mammary gland.", "content": "Liposarcoma of the female mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993677"}
{"pmid": "20993678", "title": "Deformations of the skull in head injury studied by the stresscoat technique, quantitative determinations.", "content": "Deformations of the skull in head injury studied by the stresscoat technique, quantitative determinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993678"}
{"pmid": "20993679", "title": "Spontaneous rupture of the esophagus.", "content": "Spontaneous rupture of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993679"}
{"pmid": "20993680", "title": "Diagnosis and therapeusis of simple cysts of the breast.", "content": "Diagnosis and therapeusis of simple cysts of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993680"}
{"pmid": "20993681", "title": "Surgical aspects of trench foot.", "content": "Surgical aspects of trench foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993681"}
{"pmid": "20993682", "title": "Thiouracil will not replace thyroidectomy.", "content": "Thiouracil will not replace thyroidectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993682"}
{"pmid": "20993683", "title": "Feeding tube stenosis of the larynx.", "content": "Feeding tube stenosis of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993683"}
{"pmid": "20993684", "title": "The protein nutrition of surgical patients.", "content": "The protein nutrition of surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993684"}
{"pmid": "20993685", "title": "Congenital hypertrophic pyloric stenosis.", "content": "Congenital hypertrophic pyloric stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993685"}
{"pmid": "20993686", "title": "The treatment of ununited fractures of the neck of the femur.", "content": "The treatment of ununited fractures of the neck of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993686"}
{"pmid": "20993690", "title": "MAY act is made permanent.", "content": "MAY act is made permanent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993690"}
{"pmid": "20993689", "title": "IS COMMERCIALIZED prostitution returning?", "content": "IS COMMERCIALIZED prostitution returning?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993689"}
{"pmid": "20993691", "title": "Toxicity of certain salts of sodium and potassium for swine.", "content": "Toxicity of certain salts of sodium and potassium for swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993691"}
{"pmid": "20993692", "title": "Surgical repair of an incised teat wound.", "content": "Surgical repair of an incised teat wound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993692"}
{"pmid": "20993694", "title": "A 72 percent H2SO4 method for the determination of lignin and its use in animal nutrition studies.", "content": "A 72 percent H2SO4 method for the determination of lignin and its use in animal nutrition studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993694"}
{"pmid": "20993688", "title": "VITAMIN B complex therapy.", "content": "VITAMIN B complex therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993688"}
{"pmid": "20993695", "title": "Variation in determinations of digestive capacity of sheep.", "content": "Variation in determinations of digestive capacity of sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993695"}
{"pmid": "20993687", "title": "PROGRESS in antimalarial research.", "content": "PROGRESS in antimalarial research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993687"}
{"pmid": "20993696", "title": "A modified Norman-Jenkins method for the determination of cellulose and its use in the evaluation of feedstuffs.", "content": "A modified Norman-Jenkins method for the determination of cellulose and its use in the evaluation of feedstuffs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993696"}
{"pmid": "20993697", "title": "Induction of mating and lambing in anestrous ewes following pregnant mare serum administration.", "content": "Induction of mating and lambing in anestrous ewes following pregnant mare serum administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993697"}
{"pmid": "20993705", "title": "Association of Xanthomonas phaseoli and the common bean-mosaic virus, Marmor phaseoli; dissociation studies of X. phaseoli.", "content": "Association of Xanthomonas phaseoli and the common bean-mosaic virus, Marmor phaseoli; dissociation studies of X. phaseoli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993705"}
{"pmid": "20993707", "title": "Green dwarf, a virus disease of potato.", "content": "Green dwarf, a virus disease of potato.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993707"}
{"pmid": "20993706", "title": "Association of Xanthomonas phaseoli and the common bean-mosaic virus, Marmor phaseoli; the effect of varying amounts of nitrogen on pathogenicity.", "content": "Association of Xanthomonas phaseoli and the common bean-mosaic virus, Marmor phaseoli; the effect of varying amounts of nitrogen on pathogenicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993706"}
{"pmid": "20993708", "title": "The concentration of sulphonamide in bronchial or respiratory tract fluid following oral administration.", "content": "The concentration of sulphonamide in bronchial or respiratory tract fluid following oral administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993708"}
{"pmid": "20993709", "title": "The transamination enzyme of the rat kidney.", "content": "The transamination enzyme of the rat kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993709"}
{"pmid": "20993700", "title": "Yield genes, heterosis and combining ability.", "content": "Yield genes, heterosis and combining ability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993700"}
{"pmid": "20993711", "title": "Insulin; its chemistry and physiology.", "content": "Insulin; its chemistry and physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993711"}
{"pmid": "20993699", "title": "The chromosomes of polygyrid snails.", "content": "The chromosomes of polygyrid snails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993699"}
{"pmid": "20993698", "title": "Epidemic, primary virus infections of the central nervous system of man.", "content": "Epidemic, primary virus infections of the central nervous system of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993698"}
{"pmid": "20993712", "title": "Chloride, carbonic anhydrase, and catalase in the tissues of the perch, Perca flavescens (Mitchell).", "content": "Chloride, carbonic anhydrase, and catalase in the tissues of the perch, Perca flavescens (Mitchell).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993712"}
{"pmid": "20993713", "title": "Toxemia of pregnancy and experimental hypertension; the production and the measurement of experimental renal hypertension.", "content": "Toxemia of pregnancy and experimental hypertension; the production and the measurement of experimental renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993713"}
{"pmid": "20993702", "title": "Cinematography and the study of child development.", "content": "Cinematography and the study of child development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993702"}
{"pmid": "20993714", "title": "Toxemia of pregnancy and experimental hypertension; the etiology of experimental hypertension.", "content": "Toxemia of pregnancy and experimental hypertension; the etiology of experimental hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993714"}
{"pmid": "20993701", "title": "The presence of multiple strands in chromosomes of Romalea (Orthoptera).", "content": "The presence of multiple strands in chromosomes of Romalea (Orthoptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993701"}
{"pmid": "20993703", "title": "The results of selection against expression of the short upper beak mutation in fowl.", "content": "The results of selection against expression of the short upper beak mutation in fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993703"}
{"pmid": "20993716", "title": "Inhibition and stimulation of tumor homoiotransplants by prior injections of lyophilized tumor tissue.", "content": "Inhibition and stimulation of tumor homoiotransplants by prior injections of lyophilized tumor tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993716"}
{"pmid": "20993717", "title": "Note on the enzymatic activity of normal and neoplastic tissues of the rat.", "content": "Note on the enzymatic activity of normal and neoplastic tissues of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993717"}
{"pmid": "20993719", "title": "Liver necrosis and the induction of carbon tetrachloride hepatomas in strain A mice.", "content": "Liver necrosis and the induction of carbon tetrachloride hepatomas in strain A mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993719"}
{"pmid": "20993720", "title": "Quantitative histologic analysis of the effect of x-radiation of the interstitial tissue of the testes of LAF1 mice.", "content": "Quantitative histologic analysis of the effect of x-radiation of the interstitial tissue of the testes of LAF1 mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993720"}
{"pmid": "20993718", "title": "Reactions of bis (2-chloroethyl) sulfide (mustard gas) and some of its derivatives with proteins and amino acids.", "content": "Reactions of bis (2-chloroethyl) sulfide (mustard gas) and some of its derivatives with proteins and amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993718"}
{"pmid": "20993704", "title": "Notes on graphic biometric comparisons of samples.", "content": "Notes on graphic biometric comparisons of samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993704"}
{"pmid": "20993721", "title": "Increase in incidence of lung tumors in strain A mice following long-continued irradiation with gamma rays.", "content": "Increase in incidence of lung tumors in strain A mice following long-continued irradiation with gamma rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993721"}
{"pmid": "20993722", "title": "Sulfhydryl groups in the cathepsin of rat lymphosarcoma.", "content": "Sulfhydryl groups in the cathepsin of rat lymphosarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993722"}
{"pmid": "20993723", "title": "Effect of the level of dietary protein on vascular repair in wounds.", "content": "Effect of the level of dietary protein on vascular repair in wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993723"}
{"pmid": "20993724", "title": "Quantitative studies on the latent period of tumors induced with subcutaneous injections of the agent of chicken tumor I; estimation of the latent period.", "content": "Quantitative studies on the latent period of tumors induced with subcutaneous injections of the agent of chicken tumor I; estimation of the latent period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993724"}
{"pmid": "20993730", "title": "The application to civilian practice of some dental lessons of the last war.", "content": "The application to civilian practice of some dental lessons of the last war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993730"}
{"pmid": "20993731", "title": "More light on the pyorrhea problem.", "content": "More light on the pyorrhea problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993731"}
{"pmid": "20993732", "title": "A case of alveolectomy.", "content": "A case of alveolectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993732"}
{"pmid": "20993733", "title": "Two unusual cases of necrosis of the jaws.", "content": "Two unusual cases of necrosis of the jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993733"}
{"pmid": "20993741", "title": "Lithogenesis and hypovitaminosis.", "content": "Lithogenesis and hypovitaminosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993741"}
{"pmid": "20993742", "title": "Some technical procedures in the use of dental alloys.", "content": "Some technical procedures in the use of dental alloys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993742"}
{"pmid": "20993744", "title": "Progress in the standardization of stains; twenty-five years of cooperation with the U.S. Department of Agriculture.", "content": "Progress in the standardization of stains; twenty-five years of cooperation with the U.S. Department of Agriculture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993744"}
{"pmid": "20993745", "title": "Precooling combined with chrom-osmo-acetic fixation in studies of somatic chromosomes in plants.", "content": "Precooling combined with chrom-osmo-acetic fixation in studies of somatic chromosomes in plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993745"}
{"pmid": "20993746", "title": "A modified Feulgen technic for small and diffuse chromatin elements.", "content": "A modified Feulgen technic for small and diffuse chromatin elements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993746"}
{"pmid": "20993747", "title": "An oxidation and adsorption reaction for differentiating the endodermis and the collenchyma.", "content": "An oxidation and adsorption reaction for differentiating the endodermis and the collenchyma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993747"}
{"pmid": "20993748", "title": "A rapid freehand sectioning method for leaves.", "content": "A rapid freehand sectioning method for leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993748"}
{"pmid": "20993749", "title": "Some evidence for the specificity of the Feulgen reaction.", "content": "Some evidence for the specificity of the Feulgen reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993749"}
{"pmid": "20993750", "title": "Curtis' substitute for Van Gieson stain.", "content": "Curtis' substitute for Van Gieson stain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993750"}
{"pmid": "20993751", "title": "The use of enzymes in the preparation of root-tip smears.", "content": "The use of enzymes in the preparation of root-tip smears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993751"}
{"pmid": "20993752", "title": "Mold bran; newest biological tool of syrup and fermentation industries.", "content": "Mold bran; newest biological tool of syrup and fermentation industries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993752"}
{"pmid": "20993753", "title": "Food use traced in body by new heavy carbon tool.", "content": "Food use traced in body by new heavy carbon tool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993753"}
{"pmid": "20993754", "title": "A comparison of thiamine synthesis and excretion in human subjects on synthetic and natural diets.", "content": "A comparison of thiamine synthesis and excretion in human subjects on synthetic and natural diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993754"}
{"pmid": "20993755", "title": "A comparison of riboflavin synthesis and excretion in human subjects on synthetic and natural diets.", "content": "A comparison of riboflavin synthesis and excretion in human subjects on synthetic and natural diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993755"}
{"pmid": "20993756", "title": "The development and demonstration of corneal vascularization in rats deficient in vitamin A and in riboflavin.", "content": "The development and demonstration of corneal vascularization in rats deficient in vitamin A and in riboflavin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993756"}
{"pmid": "20993757", "title": "Attempts to produce a niacin deficiency in the rhesus monkey.", "content": "Attempts to produce a niacin deficiency in the rhesus monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993757"}
{"pmid": "20993758", "title": "Nutritional significance of inositol and biotin for the pig.", "content": "Nutritional significance of inositol and biotin for the pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993758"}
{"pmid": "20993759", "title": "Cobalt metabolism studies; partition of radioactive cobalt by a rumen fistula cow.", "content": "Cobalt metabolism studies; partition of radioactive cobalt by a rumen fistula cow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993759"}
{"pmid": "20993760", "title": "Studies on the comparative nutritive value of fats.", "content": "Studies on the comparative nutritive value of fats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993760"}
{"pmid": "20993761", "title": "The nicotinic acid, biotin, and pantothenic acid content of cows milk.", "content": "The nicotinic acid, biotin, and pantothenic acid content of cows milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993761"}
{"pmid": "20993762", "title": "The effect of liver extracts on the utilization of casein for growth.", "content": "The effect of liver extracts on the utilization of casein for growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993762"}
{"pmid": "20993763", "title": "The use of the dog for studies on iron availability.", "content": "The use of the dog for studies on iron availability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993763"}
{"pmid": "20993764", "title": "Self selection of diet; the effect of flavor.", "content": "Self selection of diet; the effect of flavor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993764"}
{"pmid": "20993765", "title": "Prevention and treatment of carcinoma of the vulva.", "content": "Prevention and treatment of carcinoma of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993765"}
{"pmid": "20993766", "title": "The aspiration of stomach contents into the lungs during obstetric anesthesia.", "content": "The aspiration of stomach contents into the lungs during obstetric anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993766"}
{"pmid": "20993767", "title": "The muscle of micturition; its role in the sphincter mechanism with reference to incontinence in the female.", "content": "The muscle of micturition; its role in the sphincter mechanism with reference to incontinence in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993767"}
{"pmid": "20993768", "title": "Total abdominal hysterectomy; a study of 500 cases.", "content": "Total abdominal hysterectomy; a study of 500 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993768"}
{"pmid": "20993769", "title": "The Manchester operation, with special reference to parturition and complete prolapse; a report of 206 cases.", "content": "The Manchester operation, with special reference to parturition and complete prolapse; a report of 206 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993769"}
{"pmid": "20993770", "title": "An evaluation of extraperitoneal cesarean section.", "content": "An evaluation of extraperitoneal cesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993770"}
{"pmid": "20993771", "title": "A discussion of pelvic variation and a report on the findings in 100 Negro women.", "content": "A discussion of pelvic variation and a report on the findings in 100 Negro women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993771"}
{"pmid": "20993772", "title": "The value and limitations of pelvioradiography in the management of dystocia, with special reference to midpelvic capacity.", "content": "The value and limitations of pelvioradiography in the management of dystocia, with special reference to midpelvic capacity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993772"}
{"pmid": "20993773", "title": "Heart disease in pregnancy.", "content": "Heart disease in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993773"}
{"pmid": "20993774", "title": "Veratrum viride in the treatment of the toxemias of pregnancy.", "content": "Veratrum viride in the treatment of the toxemias of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993774"}
{"pmid": "20993775", "title": "The treatment with massive arsenotherapy of early syphilis complicated by pregnancy.", "content": "The treatment with massive arsenotherapy of early syphilis complicated by pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993775"}
{"pmid": "20993776", "title": "Critical study of 390 major gynecologic surgical procedures.", "content": "Critical study of 390 major gynecologic surgical procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993776"}
{"pmid": "20993777", "title": "Successful treatment of hydramnios with ammonium chloride; a preliminary report.", "content": "Successful treatment of hydramnios with ammonium chloride; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993777"}
{"pmid": "20993778", "title": "Sarcoma of the vagina.", "content": "Sarcoma of the vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993778"}
{"pmid": "20993780", "title": "Extrauterine pregnancy.", "content": "Extrauterine pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993780"}
{"pmid": "20993779", "title": "Hydatidiform mole, with special reference to recurrence and associated eclampsia.", "content": "Hydatidiform mole, with special reference to recurrence and associated eclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993779"}
{"pmid": "20993781", "title": "Spontaneous rupture of the liver in eclampsia with fatal hemoperitoneum.", "content": "Spontaneous rupture of the liver in eclampsia with fatal hemoperitoneum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993781"}
{"pmid": "20993782", "title": "Umbilical accessory liver.", "content": "Umbilical accessory liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993782"}
{"pmid": "20993783", "title": "Sliding hernia of the Fallopian tube.", "content": "Sliding hernia of the Fallopian tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993783"}
{"pmid": "20993784", "title": "Supernaturalism in hospital work.", "content": "Supernaturalism in hospital work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993784"}
{"pmid": "20993785", "title": "The organization of hospitals for service to the community.", "content": "The organization of hospitals for service to the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993785"}
{"pmid": "20993786", "title": "Public service rendered by the voluntary hospital.", "content": "Public service rendered by the voluntary hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993786"}
{"pmid": "20993787", "title": "The education of record librarians.", "content": "The education of record librarians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993787"}
{"pmid": "20993792", "title": "Psychology in industry.", "content": "Psychology in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993792"}
{"pmid": "20993793", "title": "Crime, some social aspects; social factors and crime.", "content": "Crime, some social aspects; social factors and crime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993793"}
{"pmid": "20993794", "title": "State welfare work in the United Kingdom.", "content": "State welfare work in the United Kingdom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993794"}
{"pmid": "20993795", "title": "Mental disorder in India; a review and a prospect.", "content": "Mental disorder in India; a review and a prospect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993795"}
{"pmid": "20993796", "title": "[JUVENILE psychoneurosis].", "content": "[JUVENILE psychoneurosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993796"}
{"pmid": "20993797", "title": "Metabolic changes induced by synthetic 11-dehydrocorticosterone acetate; including comparative studies with synthetic desoxycorticosterone acetate, natural 17-hydroxycorticosterone and lipoadrenal cortex.", "content": "Metabolic changes induced by synthetic 11-dehydrocorticosterone acetate; including comparative studies with synthetic desoxycorticosterone acetate, natural 17-hydroxycorticosterone and lipoadrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993797"}
{"pmid": "20993798", "title": "11-Dehydrocorticosterone; its effects on hypoadrenalism in man.", "content": "11-Dehydrocorticosterone; its effects on hypoadrenalism in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993798"}
{"pmid": "20993799", "title": "Primary systemic amyloidosis.", "content": "Primary systemic amyloidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993799"}
{"pmid": "20993800", "title": "Relation of cardiac enlargement to hypertension in acute and chronic glomerulonephritis.", "content": "Relation of cardiac enlargement to hypertension in acute and chronic glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993800"}
{"pmid": "20993801", "title": "Bronchogenic carcinoma.", "content": "Bronchogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993801"}
{"pmid": "20993802", "title": "Experimental and clinical evaluation of synthetic anti-histaminic drugs.", "content": "Experimental and clinical evaluation of synthetic anti-histaminic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993802"}
{"pmid": "20993803", "title": "A comparative study of the treatment of tularemia with immune serum, hyperimmune serum and streptomycin.", "content": "A comparative study of the treatment of tularemia with immune serum, hyperimmune serum and streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993803"}
{"pmid": "20993804", "title": "Bronchial asthma.", "content": "Bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993804"}
{"pmid": "20993805", "title": "Suppurative complications of bland pulmonary infarcts accompanying congestive heart failure.", "content": "Suppurative complications of bland pulmonary infarcts accompanying congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993805"}
{"pmid": "20993833", "title": "Medicine in transition.", "content": "Medicine in transition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993833"}
{"pmid": "20993834", "title": "Problems arising from the use of penicillin in gonorrhoea.", "content": "Problems arising from the use of penicillin in gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993834"}
{"pmid": "20993835", "title": "Individual resistance to malignant disease; illustrated by a case in which a metastatic deposit from a carcinoma of the breast occurred in the appendix and led to perforation and peritonitis.", "content": "Individual resistance to malignant disease; illustrated by a case in which a metastatic deposit from a carcinoma of the breast occurred in the appendix and led to perforation and peritonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993835"}
{"pmid": "20993836", "title": "Biliary peritonitis without demonstrable perforation.", "content": "Biliary peritonitis without demonstrable perforation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993836"}
{"pmid": "20993837", "title": "Epidemic pleuritic pain; a review of 17 cases in a military camp, India command.", "content": "Epidemic pleuritic pain; a review of 17 cases in a military camp, India command.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993837"}
{"pmid": "20993838", "title": "A case of human rabies in Sierra Leone.", "content": "A case of human rabies in Sierra Leone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993838"}
{"pmid": "20993839", "title": "Amenorrhoea at Stanley Camp, Hong Kong, during internment.", "content": "Amenorrhoea at Stanley Camp, Hong Kong, during internment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993839"}
{"pmid": "20993841", "title": "A simple drip-feed type of anaesthetic apparatus.", "content": "A simple drip-feed type of anaesthetic apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993841"}
{"pmid": "20993840", "title": "Silent perforation of the gut wall.", "content": "Silent perforation of the gut wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993840"}
{"pmid": "20993842", "title": "Some aspects of military otolaryngology.", "content": "Some aspects of military otolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993842"}
{"pmid": "20993843", "title": "DOCTORS in the law courts in the 13th and 16th centuries.", "content": "DOCTORS in the law courts in the 13th and 16th centuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993843"}
{"pmid": "20993844", "title": "Industrial rehabilitation.", "content": "Industrial rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993844"}
{"pmid": "20993845", "title": "Book reviewing.", "content": "Book reviewing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993845"}
{"pmid": "20993846", "title": "HEALTH Service Bill.", "content": "HEALTH Service Bill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993846"}
{"pmid": "20993852", "title": "Infectious diarrhea of the newborn.", "content": "Infectious diarrhea of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993852"}
{"pmid": "20993853", "title": "Penicillin in the treatment of neurosyphilis; dementia paralytica.", "content": "Penicillin in the treatment of neurosyphilis; dementia paralytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993853"}
{"pmid": "20993854", "title": "Pheochromocytoma and chronic hypertension.", "content": "Pheochromocytoma and chronic hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993854"}
{"pmid": "20993855", "title": "Temporal arteritis.", "content": "Temporal arteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993855"}
{"pmid": "20993856", "title": "Billroth I (von Haberer) resection of the stomach.", "content": "Billroth I (von Haberer) resection of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993856"}
{"pmid": "20993857", "title": "Leptospiral nephritis.", "content": "Leptospiral nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993857"}
{"pmid": "20993858", "title": "A case of serum sickness treated with procaine intravenously.", "content": "A case of serum sickness treated with procaine intravenously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993858"}
{"pmid": "20993859", "title": "Localization by fluorescein of fiberglass in throat.", "content": "Localization by fluorescein of fiberglass in throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993859"}
{"pmid": "20993860", "title": "DEVELOPMENTS of the Army Institute and Registry of Pathology.", "content": "DEVELOPMENTS of the Army Institute and Registry of Pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993860"}
{"pmid": "20993861", "title": "Spontaneous rupture of a hydronephrotic kidney; report of a case.", "content": "Spontaneous rupture of a hydronephrotic kidney; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993861"}
{"pmid": "20993862", "title": "Serology and obstetrics.", "content": "Serology and obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993862"}
{"pmid": "20993863", "title": "Functional disorders of the digestive tract.", "content": "Functional disorders of the digestive tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993863"}
{"pmid": "20993864", "title": "Urologic studies in chronic abdominal pain.", "content": "Urologic studies in chronic abdominal pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993864"}
{"pmid": "20993865", "title": "Hemorrhage in pregnancy.", "content": "Hemorrhage in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993865"}
{"pmid": "20993866", "title": "Carcinoma of the body of the pancreas; a case report.", "content": "Carcinoma of the body of the pancreas; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993866"}
{"pmid": "20993875", "title": "The physician's cancer.", "content": "The physician's cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993875"}
{"pmid": "20993876", "title": "The use of folic acid and other compounds in the treatment of macrocytic anemias.", "content": "The use of folic acid and other compounds in the treatment of macrocytic anemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993876"}
{"pmid": "20993877", "title": "Geriatrics.", "content": "Geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993877"}
{"pmid": "20993878", "title": "The pathogenesis of pulmonary tuberculosis.", "content": "The pathogenesis of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993878"}
{"pmid": "20993879", "title": "The aging eye.", "content": "The aging eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993879"}
{"pmid": "20993880", "title": "Protein deficiency conditions observed in private practice.", "content": "Protein deficiency conditions observed in private practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993880"}
{"pmid": "20993881", "title": "Chancroid disease and its treatment.", "content": "Chancroid disease and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993881"}
{"pmid": "20993882", "title": "The use of penicillin aerosol in bronchopulmonary and sinus infections.", "content": "The use of penicillin aerosol in bronchopulmonary and sinus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993882"}
{"pmid": "20993883", "title": "Analysis of surgical failures and fatalities following thoracolumbar sympathectomy for essential hypertension.", "content": "Analysis of surgical failures and fatalities following thoracolumbar sympathectomy for essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993883"}
{"pmid": "20993884", "title": "The use of placebos in therapy.", "content": "The use of placebos in therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993884"}
{"pmid": "20993885", "title": "The malaria patient.", "content": "The malaria patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993885"}
{"pmid": "20993886", "title": "Amoebiasis.", "content": "Amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993886"}
{"pmid": "20993887", "title": "Surgery in the tropics.", "content": "Surgery in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993887"}
{"pmid": "20993888", "title": "Heatstroke and sunstroke.", "content": "Heatstroke and sunstroke.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993888"}
{"pmid": "20993889", "title": "Skin diseases in the tropics.", "content": "Skin diseases in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993889"}
{"pmid": "20993890", "title": "Social medicine in the tropics.", "content": "Social medicine in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993890"}
{"pmid": "20993891", "title": "Rheumatic symptoms in general medicine.", "content": "Rheumatic symptoms in general medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993891"}
{"pmid": "20993892", "title": "Mushroom poisoning.", "content": "Mushroom poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993892"}
{"pmid": "20993893", "title": "Early recognition of disease; non-specific arthritis in adults.", "content": "Early recognition of disease; non-specific arthritis in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993893"}
{"pmid": "20993894", "title": "Leucorrhoea.", "content": "Leucorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993894"}
{"pmid": "20993895", "title": "Toxaemia of pregnancy.", "content": "Toxaemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993895"}
{"pmid": "20993896", "title": "Orthoptics.", "content": "Orthoptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993896"}
{"pmid": "20993936", "title": "The action of insulin on the metabolism of phosphates.", "content": "The action of insulin on the metabolism of phosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993936"}
{"pmid": "20993935", "title": "Incidence of tuberculosis in persons of known tuberculin reactivity and its bearing on BCG vaccination against tuberculosis (with special reference to nurses and medical students).", "content": "Incidence of tuberculosis in persons of known tuberculin reactivity and its bearing on BCG vaccination against tuberculosis (with special reference to nurses and medical students).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993935"}
{"pmid": "20993937", "title": "The confusion of sex.", "content": "The confusion of sex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993937"}
{"pmid": "20993938", "title": "Carcinoma of the rectum.", "content": "Carcinoma of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993938"}
{"pmid": "20993939", "title": "The development and use of penicillin.", "content": "The development and use of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993939"}
{"pmid": "20993962", "title": "Report on malaria control in rural native areas by using D. D. T. insecticide.", "content": "Report on malaria control in rural native areas by using D. D. T. insecticide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993962"}
{"pmid": "20993964", "title": "Chemical thyroidectomy.", "content": "Chemical thyroidectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993964"}
{"pmid": "20993963", "title": "Unilateral dysmenorrhoea associated with uterine malformation.", "content": "Unilateral dysmenorrhoea associated with uterine malformation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993963"}
{"pmid": "20993965", "title": "A serial investigation on the effect of tubercle endotoxoid in pulmonary tuberculosis.", "content": "A serial investigation on the effect of tubercle endotoxoid in pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993965"}
{"pmid": "20993966", "title": "Tariff of fees for medical aid societies.", "content": "Tariff of fees for medical aid societies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993966"}
{"pmid": "20993967", "title": "MENTAL hospital services in the Union; an interview with the Minister of Health, Cape Town.", "content": "MENTAL hospital services in the Union; an interview with the Minister of Health, Cape Town.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993967"}
{"pmid": "20993968", "title": "Leukopenia; its classification, etiology and treatment.", "content": "Leukopenia; its classification, etiology and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993968"}
{"pmid": "20993969", "title": "Humoral factors in experimental carcinogenesis.", "content": "Humoral factors in experimental carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993969"}
{"pmid": "20993970", "title": "The combined injection of vitamins and vaccines, with a note on typhoid agglutination titres.", "content": "The combined injection of vitamins and vaccines, with a note on typhoid agglutination titres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993970"}
{"pmid": "20993971", "title": "Urinary tract pathology engendered by changes in the generative system.", "content": "Urinary tract pathology engendered by changes in the generative system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993971"}
{"pmid": "20993972", "title": "The history and growth of the Mütter Museum.", "content": "The history and growth of the Mütter Museum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993972"}
{"pmid": "20993973", "title": "Hydropneumothorax; comparative speed of fluid absorption of two sides of the chest.", "content": "Hydropneumothorax; comparative speed of fluid absorption of two sides of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993973"}
{"pmid": "20993974", "title": "Non-nephritic uremia; the renal effects of shock.", "content": "Non-nephritic uremia; the renal effects of shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993974"}
{"pmid": "20993975", "title": "Fat metabolism and ketone body formation as shown by heavy carbon.", "content": "Fat metabolism and ketone body formation as shown by heavy carbon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993975"}
{"pmid": "20993976", "title": "Malignant exophthalmos.", "content": "Malignant exophthalmos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993976"}
{"pmid": "20993977", "title": "Recent advances in peripheral vascular disease.", "content": "Recent advances in peripheral vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993977"}
{"pmid": "20993983", "title": "Central nervous system schistosomiasis.", "content": "Central nervous system schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993983"}
{"pmid": "20993984", "title": "Rapid laboratory diagnosis of diphtheria.", "content": "Rapid laboratory diagnosis of diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993984"}
{"pmid": "20993985", "title": "Pulmonary infarction.", "content": "Pulmonary infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993985"}
{"pmid": "20993986", "title": "Surgery in the field for wounds of abdomen.", "content": "Surgery in the field for wounds of abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993986"}
{"pmid": "20993987", "title": "Tropical acne.", "content": "Tropical acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993987"}
{"pmid": "20993988", "title": "A mobile laboratory in North Africa.", "content": "A mobile laboratory in North Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993988"}
{"pmid": "20993989", "title": "The administrative aspect of combat neurosis.", "content": "The administrative aspect of combat neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993989"}
{"pmid": "20993990", "title": "Convalescence from scrub typhus.", "content": "Convalescence from scrub typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993990"}
{"pmid": "20993991", "title": "Preventive medicine.", "content": "Preventive medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993991"}
{"pmid": "20993992", "title": "Trichomonad and haemoproteus infections.", "content": "Trichomonad and haemoproteus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993992"}
{"pmid": "20993993", "title": "TREATMENT of respiratory depression and asphyxia.", "content": "TREATMENT of respiratory depression and asphyxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993993"}
{"pmid": "20993995", "title": "YAWS (frambesia).", "content": "YAWS (frambesia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993995"}
{"pmid": "20993994", "title": "CORRECTIVE lenses in welder's goggles.", "content": "CORRECTIVE lenses in welder's goggles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993994"}
{"pmid": "20993996", "title": "Simplified chlorinator.", "content": "Simplified chlorinator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993996"}
{"pmid": "20993997", "title": "Extension cylinder for x-ray field unit.", "content": "Extension cylinder for x-ray field unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993997"}
{"pmid": "20993998", "title": "Malaria control demonstration area.", "content": "Malaria control demonstration area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993998"}
{"pmid": "20993999", "title": "Traction apparatus for fractures of femur.", "content": "Traction apparatus for fractures of femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20993999"}
{"pmid": "20994000", "title": "A machine for rolling plaster of paris bandage.", "content": "A machine for rolling plaster of paris bandage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994000"}
{"pmid": "20994001", "title": "Treatment of condylomata acuminata with podophyllin.", "content": "Treatment of condylomata acuminata with podophyllin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994001"}
{"pmid": "20994002", "title": "Some practical notes for field ambulance commanders on the medical considerations in planning, mounting and carrying out combined operations in South-East Asia Command.", "content": "Some practical notes for field ambulance commanders on the medical considerations in planning, mounting and carrying out combined operations in South-East Asia Command.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994002"}
{"pmid": "20994003", "title": "An investigation of feet in Trentham Military Camp with special reference to fungus infection.", "content": "An investigation of feet in Trentham Military Camp with special reference to fungus infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994003"}
{"pmid": "20994004", "title": "Treatment of typhoid fever with convalescent whole blood.", "content": "Treatment of typhoid fever with convalescent whole blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994004"}
{"pmid": "20994005", "title": "Divisional psychiatry; report to the War Office.", "content": "Divisional psychiatry; report to the War Office.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994005"}
{"pmid": "20994006", "title": "An improvised stretcher bed with attachments.", "content": "An improvised stretcher bed with attachments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994006"}
{"pmid": "20994007", "title": "The use of D. D. T. for domestic purposes.", "content": "The use of D. D. T. for domestic purposes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994007"}
{"pmid": "20994008", "title": "The symbiotic utilization of cellulose.", "content": "The symbiotic utilization of cellulose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994008"}
{"pmid": "20994009", "title": "Archeological disclimaxes.", "content": "Archeological disclimaxes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994009"}
{"pmid": "20994010", "title": "The wounding effects of small high-velocity fragments as revealed by high-speed radiography.", "content": "The wounding effects of small high-velocity fragments as revealed by high-speed radiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994010"}
{"pmid": "20994011", "title": "Plans and problems in nuclear research.", "content": "Plans and problems in nuclear research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994011"}
{"pmid": "20994012", "title": "On reporting the comparative values and the biological activities of chemotherapeutic agents.", "content": "On reporting the comparative values and the biological activities of chemotherapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994012"}
{"pmid": "20994013", "title": "4-Thio- and 2,4-dithiobarbituric acid derivatives.", "content": "4-Thio- and 2,4-dithiobarbituric acid derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994013"}
{"pmid": "20994014", "title": "Influence of streptomycin on Type b Haemophilus influenzae.", "content": "Influence of streptomycin on Type b Haemophilus influenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994014"}
{"pmid": "20994015", "title": "Urinary recovery of penicillin after oral administration with antacids and buffers.", "content": "Urinary recovery of penicillin after oral administration with antacids and buffers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994015"}
{"pmid": "20994016", "title": "Transmission of Salmonella enteritidis by Pulex irritans and Ctenocephalus canis.", "content": "Transmission of Salmonella enteritidis by Pulex irritans and Ctenocephalus canis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994016"}
{"pmid": "20994017", "title": "Iodine as a cytological stain.", "content": "Iodine as a cytological stain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994017"}
{"pmid": "20994018", "title": "Asphyxiate and anoxiate.", "content": "Asphyxiate and anoxiate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994018"}
{"pmid": "20994019", "title": "One hundred years of Smithsonian anthropology.", "content": "One hundred years of Smithsonian anthropology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994019"}
{"pmid": "20994020", "title": "The Smithsonian; pioneer in American geology.", "content": "The Smithsonian; pioneer in American geology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994020"}
{"pmid": "20994021", "title": "A century of progress in Smithsonian biology.", "content": "A century of progress in Smithsonian biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994021"}
{"pmid": "20994022", "title": "A century of Smithsonian publications.", "content": "A century of Smithsonian publications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994022"}
{"pmid": "20994023", "title": "The International Exchange Service.", "content": "The International Exchange Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994023"}
{"pmid": "20994024", "title": "The library of the Smithsonian Institution.", "content": "The library of the Smithsonian Institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994024"}
{"pmid": "20994025", "title": "The Smithsonian deposit in the Library of Congress.", "content": "The Smithsonian deposit in the Library of Congress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994025"}
{"pmid": "20994026", "title": "Prognosis in some mental disorders.", "content": "Prognosis in some mental disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994026"}
{"pmid": "20994027", "title": "Equilibrium neurosis.", "content": "Equilibrium neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994027"}
{"pmid": "20994028", "title": "The relief of specific psychiatric symptoms by convulsive shock therapy.", "content": "The relief of specific psychiatric symptoms by convulsive shock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994028"}
{"pmid": "20994029", "title": "Reflections of an amateur neuropathologist.", "content": "Reflections of an amateur neuropathologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994029"}
{"pmid": "20994030", "title": "[Infiltrating tumor, left occipital region].", "content": "[Infiltrating tumor, left occipital region].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994030"}
{"pmid": "20994031", "title": "Electric shock therapy.", "content": "Electric shock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994031"}
{"pmid": "20994032", "title": "Nursing care of the patient with peptic ulcer.", "content": "Nursing care of the patient with peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994032"}
{"pmid": "20994033", "title": "Peacetime use of war blood plasma.", "content": "Peacetime use of war blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994033"}
{"pmid": "20994035", "title": "Why don't men nurses----?", "content": "Why don't men nurses----?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994035"}
{"pmid": "20994034", "title": "Nursing in the U.S.S.R.", "content": "Nursing in the U.S.S.R.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994034"}
{"pmid": "20994036", "title": "Finding adequate proteins when meat is scarce.", "content": "Finding adequate proteins when meat is scarce.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994036"}
{"pmid": "20994037", "title": "Modern obstetric nursing.", "content": "Modern obstetric nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994037"}
{"pmid": "20994038", "title": "Fastening the Miller-Abbott tube at the nostrils.", "content": "Fastening the Miller-Abbott tube at the nostrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994038"}
{"pmid": "20994039", "title": "Medical nursing brought up to date; changes and progress during the past five years.", "content": "Medical nursing brought up to date; changes and progress during the past five years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994039"}
{"pmid": "20994040", "title": "The rapid treatment center program; medical treatment.", "content": "The rapid treatment center program; medical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994040"}
{"pmid": "20994041", "title": "The Rapid Treatment Center; nursing services.", "content": "The Rapid Treatment Center; nursing services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994041"}
{"pmid": "20994042", "title": "Nursing service in a teaching hospital.", "content": "Nursing service in a teaching hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994042"}
{"pmid": "20994043", "title": "DESIRABLE organization of public health nursing for family service.", "content": "DESIRABLE organization of public health nursing for family service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994043"}
{"pmid": "20994044", "title": "Development of a combination agency.", "content": "Development of a combination agency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994044"}
{"pmid": "20994046", "title": "What of tuberculosis?", "content": "What of tuberculosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994046"}
{"pmid": "20994045", "title": "The tuberculosis nursing consultant.", "content": "The tuberculosis nursing consultant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994045"}
{"pmid": "20994047", "title": "Lay workers assist in a rural tuberculosis survey.", "content": "Lay workers assist in a rural tuberculosis survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994047"}
{"pmid": "20994048", "title": "Normal posture in early childhood.", "content": "Normal posture in early childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994048"}
{"pmid": "20994049", "title": "ABC's of prepayment plans.", "content": "ABC's of prepayment plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994049"}
{"pmid": "20994050", "title": "The Greater Boston Nursing Council.", "content": "The Greater Boston Nursing Council.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994050"}
{"pmid": "20994051", "title": "Health education in the health department.", "content": "Health education in the health department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994051"}
{"pmid": "20994052", "title": "The war comes home to pediatrics.", "content": "The war comes home to pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994052"}
{"pmid": "20994053", "title": "Resistance of cotton rats to the virus of poliomyelitis as affected by intake of certain purified vitamins and by sex.", "content": "Resistance of cotton rats to the virus of poliomyelitis as affected by intake of certain purified vitamins and by sex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994053"}
{"pmid": "20994054", "title": "Celiac syndrome; chemotherapy in infections of the respiratory tract associated with cystic fibrosis of the pancreas; observations with penicillin and drugs of the sulfonamide group, with special reference to penicillin aerosol.", "content": "Celiac syndrome; chemotherapy in infections of the respiratory tract associated with cystic fibrosis of the pancreas; observations with penicillin and drugs of the sulfonamide group, with special reference to penicillin aerosol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994054"}
{"pmid": "20994055", "title": "Celiac syndrome; genetics of cystic fibrosis of the pancreas, with a consideration of etiology.", "content": "Celiac syndrome; genetics of cystic fibrosis of the pancreas, with a consideration of etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994055"}
{"pmid": "20994056", "title": "Congenital duodenal obstruction; roentgen diagnosis by insufflation of air.", "content": "Congenital duodenal obstruction; roentgen diagnosis by insufflation of air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994056"}
{"pmid": "20994057", "title": "Spontaneous chylothorax in infancy; prognosis and management.", "content": "Spontaneous chylothorax in infancy; prognosis and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994057"}
{"pmid": "20994058", "title": "Role of psychiatry in a children's hospital service; account of an experiment in integrating psychiatry and pediatrics in an inpatient service.", "content": "Role of psychiatry in a children's hospital service; account of an experiment in integrating psychiatry and pediatrics in an inpatient service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994058"}
{"pmid": "20994066", "title": "The partition of potassium between the isolated lung of the dog and its perfusate with particular reference to the action of adrenaline.", "content": "The partition of potassium between the isolated lung of the dog and its perfusate with particular reference to the action of adrenaline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994066"}
{"pmid": "20994067", "title": "The effect of dietary restriction upon the incisor teeth of rachitic rats.", "content": "The effect of dietary restriction upon the incisor teeth of rachitic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994067"}
{"pmid": "20994068", "title": "Rod and cone components in the electric response of the eye.", "content": "Rod and cone components in the electric response of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994068"}
{"pmid": "20994069", "title": "The presence of a sympathomimetic substance in extracts of mammalian heart.", "content": "The presence of a sympathomimetic substance in extracts of mammalian heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994069"}
{"pmid": "20994070", "title": "The distribution of excitation and inhibition in single-fibre responses from a polarized retina.", "content": "The distribution of excitation and inhibition in single-fibre responses from a polarized retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994070"}
{"pmid": "20994071", "title": "An investigation for the presence of a skin protease inhibitory factor in burned skin.", "content": "An investigation for the presence of a skin protease inhibitory factor in burned skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994071"}
{"pmid": "20994072", "title": "Chances in intestinal tone and motility associated with nausea and vomiting.", "content": "Chances in intestinal tone and motility associated with nausea and vomiting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994072"}
{"pmid": "20994073", "title": "On the occurrence in vitro of cells resembling osteoclasts.", "content": "On the occurrence in vitro of cells resembling osteoclasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994073"}
{"pmid": "20994074", "title": "Observations on plasma volume estimations with the dye T1824.", "content": "Observations on plasma volume estimations with the dye T1824.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994074"}
{"pmid": "20994075", "title": "Reflexes elicited by visceral stimulation in the acute spinal animal.", "content": "Reflexes elicited by visceral stimulation in the acute spinal animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994075"}
{"pmid": "20994076", "title": "Visual acuity of the eye using lights of different colour.", "content": "Visual acuity of the eye using lights of different colour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994076"}
{"pmid": "20994077", "title": "The repair of the retinal image.", "content": "The repair of the retinal image.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994077"}
{"pmid": "20994078", "title": "The colour vision obtained by micro-stimulation of the human retina.", "content": "The colour vision obtained by micro-stimulation of the human retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994078"}
{"pmid": "20994079", "title": "Cluster formation by the foveal cones.", "content": "Cluster formation by the foveal cones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994079"}
{"pmid": "20994080", "title": "Synthesis of acetylcholine by non-nervous tissue.", "content": "Synthesis of acetylcholine by non-nervous tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994080"}
{"pmid": "20994081", "title": "Smooth muscle of the inferior palpebra activated by adrenergic sympathetic nerves.", "content": "Smooth muscle of the inferior palpebra activated by adrenergic sympathetic nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994081"}
{"pmid": "20994082", "title": "Phosphocreatine and the synthesis of acetylcholine.", "content": "Phosphocreatine and the synthesis of acetylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994082"}
{"pmid": "20994083", "title": "A simple rocking tray for staining histological preparations.", "content": "A simple rocking tray for staining histological preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994083"}
{"pmid": "20994084", "title": "Simple demonstrations of the reaction of cysteine with chloropicrine and allylisosulphocyanide.", "content": "Simple demonstrations of the reaction of cysteine with chloropicrine and allylisosulphocyanide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994084"}
{"pmid": "20994085", "title": "Dietary protein and histological structure of liver tissue.", "content": "Dietary protein and histological structure of liver tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994085"}
{"pmid": "20994086", "title": "An improved nerve-muscle preparation stimulator for student use.", "content": "An improved nerve-muscle preparation stimulator for student use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994086"}
{"pmid": "20994088", "title": "Heparin and trauma effects in blood.", "content": "Heparin and trauma effects in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994088"}
{"pmid": "20994087", "title": "An index of renal tubular activity.", "content": "An index of renal tubular activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994087"}
{"pmid": "20994089", "title": "Diuretic action of cyanate.", "content": "Diuretic action of cyanate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994089"}
{"pmid": "20994090", "title": "Mechanical model of heart and circulation.", "content": "Mechanical model of heart and circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994090"}
{"pmid": "20994091", "title": "Differences in localization, by histochemical means, of alkaline phosphatase within the same organ of different experimental animals.", "content": "Differences in localization, by histochemical means, of alkaline phosphatase within the same organ of different experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994091"}
{"pmid": "20994092", "title": "A simple device for recording the action of drugs on motility of rats.", "content": "A simple device for recording the action of drugs on motility of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994092"}
{"pmid": "20994093", "title": "An experimental analysis of the human jugular pulse tracing.", "content": "An experimental analysis of the human jugular pulse tracing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994093"}
{"pmid": "20994094", "title": "The output of the heart of the foetal sheep.", "content": "The output of the heart of the foetal sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994094"}
{"pmid": "20994095", "title": "Effects of temperature and anaesthetics on spontaneous rhythmic contractions of body-wall muscle of the earthworm.", "content": "Effects of temperature and anaesthetics on spontaneous rhythmic contractions of body-wall muscle of the earthworm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994095"}
{"pmid": "20994096", "title": "Q FEVER, a foreword; introduction to a series of papers dealing with Q fever.", "content": "Q FEVER, a foreword; introduction to a series of papers dealing with Q fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994096"}
{"pmid": "20994097", "title": "Q fever in the Mediterranean area; report of its occurrence in Allied troops; clinical features of the disease.", "content": "Q fever in the Mediterranean area; report of its occurrence in Allied troops; clinical features of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994097"}
{"pmid": "20994098", "title": "Q fever in the Mediterranean area; report of its occurrence in Allied troops; epidemiology.", "content": "Q fever in the Mediterranean area; report of its occurrence in Allied troops; epidemiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994098"}
{"pmid": "20994099", "title": "Q fever in the Mediterranean area; report of its occurrence in Allied troops; the etiological agent.", "content": "Q fever in the Mediterranean area; report of its occurrence in Allied troops; the etiological agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994099"}
{"pmid": "20994100", "title": "Q fever in the Mediterranean area; report of its occurrence in Allied troops; a laboratory outbreak.", "content": "Q fever in the Mediterranean area; report of its occurrence in Allied troops; a laboratory outbreak.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994100"}
{"pmid": "20994101", "title": "Epidemics of Q fever among troops returning from Italy in the spring of 1945; clinical aspects of the epidemic at Camp Patrick Henry, Virginia.", "content": "Epidemics of Q fever among troops returning from Italy in the spring of 1945; clinical aspects of the epidemic at Camp Patrick Henry, Virginia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994101"}
{"pmid": "20994102", "title": "EPIDEMICS of Q fever among troops returning from Italy in the spring of 1945; epidemiological studies.", "content": "EPIDEMICS of Q fever among troops returning from Italy in the spring of 1945; epidemiological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994102"}
{"pmid": "20994103", "title": "EPIDEMICS of Q fever among troops returning from Italy in the spring of 1945; etiological studies.", "content": "EPIDEMICS of Q fever among troops returning from Italy in the spring of 1945; etiological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994103"}
{"pmid": "20994104", "title": "IDENTIFICATION and characteristics of the Balkan grippe strain of Rickettsia burneti.", "content": "IDENTIFICATION and characteristics of the Balkan grippe strain of Rickettsia burneti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994104"}
{"pmid": "20994105", "title": "LABORATORY outbreak of Q fever caused by the Balkan grippe strain of Rickettsia burneti.", "content": "LABORATORY outbreak of Q fever caused by the Balkan grippe strain of Rickettsia burneti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994105"}
{"pmid": "20994106", "title": "The identification of Q fever in Panama.", "content": "The identification of Q fever in Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994106"}
{"pmid": "20994111", "title": "A simple and accurate method for the localisation of intraocular foreign bodies.", "content": "A simple and accurate method for the localisation of intraocular foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994111"}
{"pmid": "20994107", "title": "Q fever; an immunological comparison of strains.", "content": "Q fever; an immunological comparison of strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994107"}
{"pmid": "20994109", "title": "The physicist in the radiodiagnostic department.", "content": "The physicist in the radiodiagnostic department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994109"}
{"pmid": "20994110", "title": "Calcium gluconate injection into muscle.", "content": "Calcium gluconate injection into muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994110"}
{"pmid": "20994112", "title": "Milk of calcium or limy bile.", "content": "Milk of calcium or limy bile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994112"}
{"pmid": "20994114", "title": "The effect of extra vitamin B feeding on rats exposed to weak gamma radiation.", "content": "The effect of extra vitamin B feeding on rats exposed to weak gamma radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994114"}
{"pmid": "20994115", "title": "The preparation of radiosulphur (S35) and its determination in biological tracer experiments.", "content": "The preparation of radiosulphur (S35) and its determination in biological tracer experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994115"}
{"pmid": "20994113", "title": "A note on radiography as an aid to beam direction in radiotherapy.", "content": "A note on radiography as an aid to beam direction in radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994113"}
{"pmid": "20994116", "title": "Assessment of dosage from linear radium sources.", "content": "Assessment of dosage from linear radium sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994116"}
{"pmid": "20994117", "title": "A computor for x-ray isodose curve production.", "content": "A computor for x-ray isodose curve production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994117"}
{"pmid": "20994119", "title": "Hemoptisis.", "content": "Hemoptisis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994119"}
{"pmid": "20994126", "title": "The hazards of parachuting.", "content": "The hazards of parachuting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994126"}
{"pmid": "20994127", "title": "Inguinal hernia; the unpredictable result.", "content": "Inguinal hernia; the unpredictable result.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994127"}
{"pmid": "20994128", "title": "The surgical treatment of carcinoma of the oesophagus; with special reference to a new operation for growths of the middle third.", "content": "The surgical treatment of carcinoma of the oesophagus; with special reference to a new operation for growths of the middle third.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994128"}
{"pmid": "20994129", "title": "Chronic osteomyelitis, the sequel to a gunsh ot wound.", "content": "Chronic osteomyelitis, the sequel to a gunsh ot wound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994129"}
{"pmid": "20994130", "title": "A study of the fate of nerve homografts in man.", "content": "A study of the fate of nerve homografts in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994130"}
{"pmid": "20994131", "title": "Analysis of a series of 454 inguinal herniae with special reference to morbidity and recurrence after the whole skin-graft method.", "content": "Analysis of a series of 454 inguinal herniae with special reference to morbidity and recurrence after the whole skin-graft method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994131"}
{"pmid": "20994132", "title": "A case of Albright's syndrome (osteitis fibrosa disseminata).", "content": "A case of Albright's syndrome (osteitis fibrosa disseminata).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994132"}
{"pmid": "20994133", "title": "Saccular diverticulosis of the jejunum due to reticulum-cell sarcoma.", "content": "Saccular diverticulosis of the jejunum due to reticulum-cell sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994133"}
{"pmid": "20994134", "title": "A further review of the interinnomino-abdominal operation, based on 21 personal cases.", "content": "A further review of the interinnomino-abdominal operation, based on 21 personal cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994134"}
{"pmid": "20994135", "title": "A discussion on the treatment of injuries to the hand.", "content": "A discussion on the treatment of injuries to the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994135"}
{"pmid": "20994136", "title": "Dislocation of the inferior radio-ulnar joint.", "content": "Dislocation of the inferior radio-ulnar joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994136"}
{"pmid": "20994137", "title": "Dislocation of the scaphoid.", "content": "Dislocation of the scaphoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994137"}
{"pmid": "20994138", "title": "A case of acute anaerobic streptococcal infection of the neck of denal origin.", "content": "A case of acute anaerobic streptococcal infection of the neck of denal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994138"}
{"pmid": "20994139", "title": "Derangement of midgut rotation producing volvulus; a report of two cases.", "content": "Derangement of midgut rotation producing volvulus; a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994139"}
{"pmid": "20994140", "title": "Resection of the head of the pancreas.", "content": "Resection of the head of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994140"}
{"pmid": "20994141", "title": "Brodie's disease of the breast.", "content": "Brodie's disease of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994141"}
{"pmid": "20994142", "title": "Complete torsion of a fibroid uterus with its adnexa.", "content": "Complete torsion of a fibroid uterus with its adnexa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994142"}
{"pmid": "20994145", "title": "A congenital melanoma of lip with cystic degeneration.", "content": "A congenital melanoma of lip with cystic degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994145"}
{"pmid": "20994143", "title": "Ileocolic intussusception associated with non-rotation of the midgut, congenital heart disease, and congenital hydrocele.", "content": "Ileocolic intussusception associated with non-rotation of the midgut, congenital heart disease, and congenital hydrocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994143"}
{"pmid": "20994144", "title": "Acute miliary actinomycosis following perforated gastric ulcer.", "content": "Acute miliary actinomycosis following perforated gastric ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994144"}
{"pmid": "20994146", "title": "Acute diaphragmatic hernia associated with intestinal obstruction.", "content": "Acute diaphragmatic hernia associated with intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994146"}
{"pmid": "20994147", "title": "Congenital fusion of lunate and triquetrum.", "content": "Congenital fusion of lunate and triquetrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994147"}
{"pmid": "20994148", "title": "A case of chronic bilateral subphrenic abscesses.", "content": "A case of chronic bilateral subphrenic abscesses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994148"}
{"pmid": "20994156", "title": "Salvaging medical education in the Philippines.", "content": "Salvaging medical education in the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994156"}
{"pmid": "20994149", "title": "Improvements in the single stage operation, without colostomy for cancer of the large bowel.", "content": "Improvements in the single stage operation, without colostomy for cancer of the large bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994149"}
{"pmid": "20994150", "title": "Carcinoma of the uterus; the question of treatment by surgery or irradiation.", "content": "Carcinoma of the uterus; the question of treatment by surgery or irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994150"}
{"pmid": "20994152", "title": "The choice of treatment for carcinoma of cervix uteri.", "content": "The choice of treatment for carcinoma of cervix uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994152"}
{"pmid": "20994155", "title": "Surgical lessons learned in the past war.", "content": "Surgical lessons learned in the past war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994155"}
{"pmid": "20994151", "title": "Exomphalos.", "content": "Exomphalos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994151"}
{"pmid": "20994153", "title": "Microscopically verified success of pinch homografting in a human case.", "content": "Microscopically verified success of pinch homografting in a human case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994153"}
{"pmid": "20994154", "title": "Gas gangrene; bacteremia and carbohydrogenic toxemia.", "content": "Gas gangrene; bacteremia and carbohydrogenic toxemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994154"}
{"pmid": "20994157", "title": "The diagnosis of thyrotoxicosis.", "content": "The diagnosis of thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994157"}
{"pmid": "20994158", "title": "Ainhum; report of a case.", "content": "Ainhum; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994158"}
{"pmid": "20994173", "title": "Reactions to penicillin.", "content": "Reactions to penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994173"}
{"pmid": "20994172", "title": "Penicillin dermatitis based on tuberculin-type sensitivity; report of a case with remarks on experimental sensitization to penicillin.", "content": "Penicillin dermatitis based on tuberculin-type sensitivity; report of a case with remarks on experimental sensitization to penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994172"}
{"pmid": "20994170", "title": "Blood studies in allergy; variations of total leukocytes following test feeding of foods; an appraisal of the individual food test.", "content": "Blood studies in allergy; variations of total leukocytes following test feeding of foods; an appraisal of the individual food test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994170"}
{"pmid": "20994175", "title": "Hydatid allergy.", "content": "Hydatid allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994175"}
{"pmid": "20994178", "title": "Sedimentation rate; a diagnostic aid in allergy.", "content": "Sedimentation rate; a diagnostic aid in allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994178"}
{"pmid": "20994181", "title": "Influence of the liver in anaphylactic shock.", "content": "Influence of the liver in anaphylactic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994181"}
{"pmid": "20994182", "title": "Mango dermatitis and its relationship to poison ivy hypersensitivity.", "content": "Mango dermatitis and its relationship to poison ivy hypersensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994182"}
{"pmid": "20994171", "title": "Ethylene disulphonate in chronic asthma.", "content": "Ethylene disulphonate in chronic asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994171"}
{"pmid": "20994179", "title": "The house dust antigen; a critical review of the literature.", "content": "The house dust antigen; a critical review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994179"}
{"pmid": "20994174", "title": "Combined penicillin and hydrogen peroxide aerosol therapy in lung infections.", "content": "Combined penicillin and hydrogen peroxide aerosol therapy in lung infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994174"}
{"pmid": "20994176", "title": "Asthma due to bee scent.", "content": "Asthma due to bee scent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994176"}
{"pmid": "20994177", "title": "Headaches.", "content": "Headaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994177"}
{"pmid": "20994180", "title": "Bronchial asthma in the young male adult; a study of 100 hospitalized patients in an Army general hospital, with special reference to nasal symptoms and findings.", "content": "Bronchial asthma in the young male adult; a study of 100 hospitalized patients in an Army general hospital, with special reference to nasal symptoms and findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994180"}
{"pmid": "20994196", "title": "The pathologic effects of an instantaneous dose of radiation.", "content": "The pathologic effects of an instantaneous dose of radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994196"}
{"pmid": "20994186", "title": "Malaria and urticaria.", "content": "Malaria and urticaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994186"}
{"pmid": "20994197", "title": "The carcinogenic activity of some new derivatives of aromatic hydrocarbons; compounds related to 1,2-benzanthracene.", "content": "The carcinogenic activity of some new derivatives of aromatic hydrocarbons; compounds related to 1,2-benzanthracene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994197"}
{"pmid": "20994190", "title": "Pharmacological and clinical studies of tridione with special reference to its analgesic action.", "content": "Pharmacological and clinical studies of tridione with special reference to its analgesic action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994190"}
{"pmid": "20994189", "title": "Intravenous procaine for obstetrical anesthesia.*", "content": "Intravenous procaine for obstetrical anesthesia.*", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994189"}
{"pmid": "20994187", "title": "Generalized chronic dermatitis due to tattoo.", "content": "Generalized chronic dermatitis due to tattoo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994187"}
{"pmid": "20994184", "title": "Benadryl in the treatment of erythema exudativum multiforme.", "content": "Benadryl in the treatment of erythema exudativum multiforme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994184"}
{"pmid": "20994185", "title": "Sensitivity to thiamine hydrochloride; a potential hazard in a common office procedure.", "content": "Sensitivity to thiamine hydrochloride; a potential hazard in a common office procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994185"}
{"pmid": "20994198", "title": "The effect of diets containing an abundance of milk, liver, riboflavin, and xanthine on methylcholanthrene carcinogenesis.", "content": "The effect of diets containing an abundance of milk, liver, riboflavin, and xanthine on methylcholanthrene carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994198"}
{"pmid": "20994199", "title": "The pathology of malignant histiocytoma (reticuloendothelioma) of the liver in mice.", "content": "The pathology of malignant histiocytoma (reticuloendothelioma) of the liver in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994199"}
{"pmid": "20994200", "title": "The betatron.", "content": "The betatron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994200"}
{"pmid": "20994195", "title": "Complications following anesthesia in a case of Lutembacher's syndrome.*", "content": "Complications following anesthesia in a case of Lutembacher's syndrome.*", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994195"}
{"pmid": "20994188", "title": "Bronchial asthma.", "content": "Bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994188"}
{"pmid": "20994201", "title": "Some experimental results obtained during the war in the Laboratoire Pasteur de l'Institut de radium de Paris.", "content": "Some experimental results obtained during the war in the Laboratoire Pasteur de l'Institut de radium de Paris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994201"}
{"pmid": "20994192", "title": "The use of curare and cyclopropane in one hundred surgical cases.", "content": "The use of curare and cyclopropane in one hundred surgical cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994192"}
{"pmid": "20994191", "title": "Seconal as a basal anesthetic agent in children: a preliminary report.", "content": "Seconal as a basal anesthetic agent in children: a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994191"}
{"pmid": "20994183", "title": "Some clinical observations on the use of benadryl for the symptomatic relief of allergic conditions.", "content": "Some clinical observations on the use of benadryl for the symptomatic relief of allergic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994183"}
{"pmid": "20994202", "title": "Carcinogenesis and cell adaptations.", "content": "Carcinogenesis and cell adaptations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994202"}
{"pmid": "20994203", "title": "The influence of a rest period on the carcinogenicity of ultraviolet irradiation applied in interrupted doses.", "content": "The influence of a rest period on the carcinogenicity of ultraviolet irradiation applied in interrupted doses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994203"}
{"pmid": "20994204", "title": "DETERMINATION of phenols in soaps.", "content": "DETERMINATION of phenols in soaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994204"}
{"pmid": "20994205", "title": "The determination of leptazol in solution.", "content": "The determination of leptazol in solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994205"}
{"pmid": "20994193", "title": "Clinical anesthesia in children.", "content": "Clinical anesthesia in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994193"}
{"pmid": "20994206", "title": "Colorimetric methods for the detection and determination of DDT.", "content": "Colorimetric methods for the detection and determination of DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994206"}
{"pmid": "20994194", "title": "Some clinical experiences with (oenethyl) 2-methyl-amino-heptane as a vasopressor substance.", "content": "Some clinical experiences with (oenethyl) 2-methyl-amino-heptane as a vasopressor substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994194"}
{"pmid": "20994208", "title": "The determination of phosphorus in steel containing titanium and arsenic.", "content": "The determination of phosphorus in steel containing titanium and arsenic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994208"}
{"pmid": "20994207", "title": "Rapid estimation of phosphoric acid in citric acid soil extracts.", "content": "Rapid estimation of phosphoric acid in citric acid soil extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994207"}
{"pmid": "20994209", "title": "The determination of small amounts of aluminium in steel.", "content": "The determination of small amounts of aluminium in steel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994209"}
{"pmid": "20994210", "title": "Some experiments on the electrolytic separation of lead, as dioxide, from manganese.", "content": "Some experiments on the electrolytic separation of lead, as dioxide, from manganese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994210"}
{"pmid": "20994211", "title": "Some useful microchemical apparatus.", "content": "Some useful microchemical apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994211"}
{"pmid": "20994213", "title": "Determination of fermate (ferric dimethyldithiocarbamate).", "content": "Determination of fermate (ferric dimethyldithiocarbamate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994213"}
{"pmid": "20994212", "title": "Note on the estimation of bilirubin in blood plasma and serum.", "content": "Note on the estimation of bilirubin in blood plasma and serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994212"}
{"pmid": "20994214", "title": "Determination of carbonate in solid materials.", "content": "Determination of carbonate in solid materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994214"}
{"pmid": "20994215", "title": "Denture relining and acrylic burns.", "content": "Denture relining and acrylic burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994215"}
{"pmid": "20994220", "title": "Frozen foods for institutional use.", "content": "Frozen foods for institutional use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994220"}
{"pmid": "20994221", "title": "Retention of nutrients in quick-frozen foods.", "content": "Retention of nutrients in quick-frozen foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994221"}
{"pmid": "20994223", "title": "The effect of fresh grapefruit juice and commercially canned tomato juice on calcium retention.", "content": "The effect of fresh grapefruit juice and commercially canned tomato juice on calcium retention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994223"}
{"pmid": "20994222", "title": "Stability of vitamins in stored ice cream.", "content": "Stability of vitamins in stored ice cream.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994222"}
{"pmid": "20994224", "title": "Effect of large-scale food preparation on vitamin retention; cabbage.", "content": "Effect of large-scale food preparation on vitamin retention; cabbage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994224"}
{"pmid": "20994225", "title": "Foof preparation and service equipment for hospitals.", "content": "Foof preparation and service equipment for hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994225"}
{"pmid": "20994226", "title": "Some effects of gum chewing on gastric acidity in healthy individuals.", "content": "Some effects of gum chewing on gastric acidity in healthy individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994226"}
{"pmid": "20994217", "title": "Recurrent aphthous ulceration of oral mucous membrane and genitals associated with recurrent hypopyon iritis (Behcet's syndrome).", "content": "Recurrent aphthous ulceration of oral mucous membrane and genitals associated with recurrent hypopyon iritis (Behcet's syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994217"}
{"pmid": "20994227", "title": "Tyrothricin in proctology.", "content": "Tyrothricin in proctology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994227"}
{"pmid": "20994228", "title": "Radiation therapy of the cancer of the esophagus.", "content": "Radiation therapy of the cancer of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994228"}
{"pmid": "20994218", "title": "Myxoedema circumscriptum thyrotoxicum.", "content": "Myxoedema circumscriptum thyrotoxicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994218"}
{"pmid": "20994216", "title": "Prospect and retrospect.", "content": "Prospect and retrospect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994216"}
{"pmid": "20994229", "title": "Brief psychotherapy in the treatment of gastro-intestinal disorders.", "content": "Brief psychotherapy in the treatment of gastro-intestinal disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994229"}
{"pmid": "20994230", "title": "Gastro-intestinal symptomatology in schizophrenia.", "content": "Gastro-intestinal symptomatology in schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994230"}
{"pmid": "20994231", "title": "Peptic ulcer; a roentgenological, laboratory, and clinical follow-up of 200 peptic ulcers.", "content": "Peptic ulcer; a roentgenological, laboratory, and clinical follow-up of 200 peptic ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994231"}
{"pmid": "20994232", "title": "Continuous drip treatment for chronic ulcerative colitis.", "content": "Continuous drip treatment for chronic ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994232"}
{"pmid": "20994219", "title": "Dermatology in B. L. A.", "content": "Dermatology in B. L. A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994219"}
{"pmid": "20994233", "title": "Results of hepatic tests in chronic hepatitis without jaundice; correlation with the clinical course and liver biopsy findings.", "content": "Results of hepatic tests in chronic hepatitis without jaundice; correlation with the clinical course and liver biopsy findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994233"}
{"pmid": "20994234", "title": "A study of the time of healing of peptic ulcer in a series of sixty-nine cases of duodenal and gastric craters.", "content": "A study of the time of healing of peptic ulcer in a series of sixty-nine cases of duodenal and gastric craters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994234"}
{"pmid": "20994235", "title": "Nocturnal gastric secretion; studies on normal subjects and patients with duodenal ulcer.", "content": "Nocturnal gastric secretion; studies on normal subjects and patients with duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994235"}
{"pmid": "20994236", "title": "Complications of chronic non-specific ulcerative colitis.", "content": "Complications of chronic non-specific ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994236"}
{"pmid": "20994237", "title": "The etiology of ulcerative colitis; an analytical review of the literature.", "content": "The etiology of ulcerative colitis; an analytical review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994237"}
{"pmid": "20994239", "title": "Clinical observations on the use of benadryl; its effect on histamine-induced gastric acidity in man.", "content": "Clinical observations on the use of benadryl; its effect on histamine-induced gastric acidity in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994239"}
{"pmid": "20994238", "title": "Some results of the gastric secretory response of patients having duodenal ulcer noted during the administration of benadryl.", "content": "Some results of the gastric secretory response of patients having duodenal ulcer noted during the administration of benadryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994238"}
{"pmid": "20994240", "title": "Separation and assay of secretin and cholecystokinin.", "content": "Separation and assay of secretin and cholecystokinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994240"}
{"pmid": "20994242", "title": "Hypernephroma, left kidney, with metastases to the peritoneum, liver and lung.", "content": "Hypernephroma, left kidney, with metastases to the peritoneum, liver and lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994242"}
{"pmid": "20994241", "title": "[Hodgkin's disease demonstrated microscopically in the lymph nodes, prostate, kidney, periadrenal tissue, lung, pancreas, liver, and spleen].", "content": "[Hodgkin's disease demonstrated microscopically in the lymph nodes, prostate, kidney, periadrenal tissue, lung, pancreas, liver, and spleen].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994241"}
{"pmid": "20994243", "title": "HISTAMINE and gastric secretion in relation to anti-histamine drugs.", "content": "HISTAMINE and gastric secretion in relation to anti-histamine drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994243"}
{"pmid": "20994252", "title": "Activation of the anterior hypophysis by electrical stimulation in the rabbit.", "content": "Activation of the anterior hypophysis by electrical stimulation in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994252"}
{"pmid": "20994251", "title": "The effect of thiouracil hypothyroidism on reproduction in the rat.", "content": "The effect of thiouracil hypothyroidism on reproduction in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994251"}
{"pmid": "20994253", "title": "Adenosine triphosphatase activity of lutein and ovarian tissues and weight of corpora lutea during the reproductive cycle of the rat.", "content": "Adenosine triphosphatase activity of lutein and ovarian tissues and weight of corpora lutea during the reproductive cycle of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994253"}
{"pmid": "20994254", "title": "Local inhibition of hair growth in dogs by percutaneous application of estrone.", "content": "Local inhibition of hair growth in dogs by percutaneous application of estrone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994254"}
{"pmid": "20994255", "title": "The chemical changes in rat adrenals after injection of betachloroethyl vesicants.", "content": "The chemical changes in rat adrenals after injection of betachloroethyl vesicants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994255"}
{"pmid": "20994245", "title": "Diverticulitis of the colon.", "content": "Diverticulitis of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994245"}
{"pmid": "20994256", "title": "The chemical cytology of the rat's adrenal cortex in pantothenic acid deficiency.", "content": "The chemical cytology of the rat's adrenal cortex in pantothenic acid deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994256"}
{"pmid": "20994257", "title": "Chemical structure and progesterone-like activity.", "content": "Chemical structure and progesterone-like activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994257"}
{"pmid": "20994258", "title": "The toxicity of the serum of adrenalectomized animals.", "content": "The toxicity of the serum of adrenalectomized animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994258"}
{"pmid": "20994244", "title": "Dietotherapy in gastrointestinal diseases; dietotherapy of hyperacidity, hypacidity, peptic ulcer (uncomplicated), chronic gastritis and gastric neurosis associated with hunger discomfort.", "content": "Dietotherapy in gastrointestinal diseases; dietotherapy of hyperacidity, hypacidity, peptic ulcer (uncomplicated), chronic gastritis and gastric neurosis associated with hunger discomfort.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994244"}
{"pmid": "20994246", "title": "Gastrointestinal disorders associated with or simulated by lesions of the genitourinary tract.", "content": "Gastrointestinal disorders associated with or simulated by lesions of the genitourinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994246"}
{"pmid": "20994247", "title": "Preoperative management of segmental enteritis.", "content": "Preoperative management of segmental enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994247"}
{"pmid": "20994248", "title": "The influence of hyperthyroidism in clinical and secretory functions of gastric juice.", "content": "The influence of hyperthyroidism in clinical and secretory functions of gastric juice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994248"}
{"pmid": "20994249", "title": "Proctoenterology.", "content": "Proctoenterology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994249"}
{"pmid": "20994250", "title": "Errors of credit priority.", "content": "Errors of credit priority.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994250"}
{"pmid": "20994266", "title": "The influence of the concept of monomania on French medico-legal psychiatry (from 1825 to 1840).", "content": "The influence of the concept of monomania on French medico-legal psychiatry (from 1825 to 1840).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994266"}
{"pmid": "20994267", "title": "Students of physic and astrology; a survey of astrological medicine in the age of science.", "content": "Students of physic and astrology; a survey of astrological medicine in the age of science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994267"}
{"pmid": "20994268", "title": "The Smithsonian Institution.", "content": "The Smithsonian Institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994268"}
{"pmid": "20994270", "title": "Case of cancer of left parotid.", "content": "Case of cancer of left parotid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994270"}
{"pmid": "20994269", "title": "Why homeopathy is the only science of healing.", "content": "Why homeopathy is the only science of healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994269"}
{"pmid": "20994264", "title": "What is old age?", "content": "What is old age?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994264"}
{"pmid": "20994263", "title": "The army of the aged; a sociomedical problem.", "content": "The army of the aged; a sociomedical problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994263"}
{"pmid": "20994271", "title": "The atomic energy principles in the treatment of the patient.", "content": "The atomic energy principles in the treatment of the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994271"}
{"pmid": "20994260", "title": "Tonsils and aging.", "content": "Tonsils and aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994260"}
{"pmid": "20994273", "title": "Osteopathic objectives.", "content": "Osteopathic objectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994273"}
{"pmid": "20994275", "title": "Similar effects of different lesions.", "content": "Similar effects of different lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994275"}
{"pmid": "20994274", "title": "The psychophysiological aspect of labor.", "content": "The psychophysiological aspect of labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994274"}
{"pmid": "20994261", "title": "Are geriatrics mortality and morbidity statistics reliable?", "content": "Are geriatrics mortality and morbidity statistics reliable?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994261"}
{"pmid": "20994259", "title": "The management of parenteral fluids in geriatrics.", "content": "The management of parenteral fluids in geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994259"}
{"pmid": "20994272", "title": "A way of escape from the Wagner-Truman federal health proposals.", "content": "A way of escape from the Wagner-Truman federal health proposals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994272"}
{"pmid": "20994262", "title": "Reported effects of antireticulo-cytotoxic serum developed in Russia.", "content": "Reported effects of antireticulo-cytotoxic serum developed in Russia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994262"}
{"pmid": "20994276", "title": "Predicting length of hospitalization of mental patients.", "content": "Predicting length of hospitalization of mental patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994276"}
{"pmid": "20994265", "title": "Are old men at the throttle the cause of railroad accidents?", "content": "Are old men at the throttle the cause of railroad accidents?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994265"}
{"pmid": "20994277", "title": "German reactions to Nazi atrocities.", "content": "German reactions to Nazi atrocities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994277"}
{"pmid": "20994278", "title": "Hood and booth types available to solve typical ventilation problems.", "content": "Hood and booth types available to solve typical ventilation problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994278"}
{"pmid": "20994279", "title": "Lead poisoning and compensation.", "content": "Lead poisoning and compensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994279"}
{"pmid": "20994280", "title": "Health protection in the production and use of atomic energy.", "content": "Health protection in the production and use of atomic energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994280"}
{"pmid": "20994281", "title": "Anthrax; its diagnosis and treatment.", "content": "Anthrax; its diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994281"}
{"pmid": "20994283", "title": "Surgery in industry.", "content": "Surgery in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994283"}
{"pmid": "20994282", "title": "Importance of researches on war gases to clinical medicine.", "content": "Importance of researches on war gases to clinical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994282"}
{"pmid": "20994284", "title": "A disease resulting from the use of pneumatic tools.", "content": "A disease resulting from the use of pneumatic tools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994284"}
{"pmid": "20994285", "title": "Practical benefits of industrial health service.", "content": "Practical benefits of industrial health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994285"}
{"pmid": "20994291", "title": "Repair of defects and fistulae in the urinary bladder.", "content": "Repair of defects and fistulae in the urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994291"}
{"pmid": "20994292", "title": "The use of cellophane in the treatment of wounds.", "content": "The use of cellophane in the treatment of wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994292"}
{"pmid": "20994293", "title": "Fermentation in pus.", "content": "Fermentation in pus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994293"}
{"pmid": "20994294", "title": "The physicochemical nature of antibiotic action.", "content": "The physicochemical nature of antibiotic action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994294"}
{"pmid": "20994295", "title": "Bacteriostatic substances of animal origin.", "content": "Bacteriostatic substances of animal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994295"}
{"pmid": "20994296", "title": "Vaccination against typhus.", "content": "Vaccination against typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994296"}
{"pmid": "20994297", "title": "Specific prophylaxis and the early diagnosis of typhus.", "content": "Specific prophylaxis and the early diagnosis of typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994297"}
{"pmid": "20994298", "title": "Significance of basic argyrophil substance in the pathogenesis of hypertension.", "content": "Significance of basic argyrophil substance in the pathogenesis of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994298"}
{"pmid": "20994299", "title": "Balneologic treatment of chronic osteomyelitis.", "content": "Balneologic treatment of chronic osteomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994299"}
{"pmid": "20994300", "title": "The problem of prolonged hepatitis with particular reference to the cholangiolitic type and to the development of cholangiolitic cirrhosis of the liver.", "content": "The problem of prolonged hepatitis with particular reference to the cholangiolitic type and to the development of cholangiolitic cirrhosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994300"}
{"pmid": "20994301", "title": "Medicine and education.", "content": "Medicine and education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994301"}
{"pmid": "20994302", "title": "The nutritional status of Japanese prisoners of war, Burma 1945.", "content": "The nutritional status of Japanese prisoners of war, Burma 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994302"}
{"pmid": "20994303", "title": "Beriberi in Japanese prison camp.", "content": "Beriberi in Japanese prison camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994303"}
{"pmid": "20994304", "title": "Sudden death in rheumatic fever.", "content": "Sudden death in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994304"}
{"pmid": "20994305", "title": "The malaria triad.", "content": "The malaria triad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994305"}
{"pmid": "20994306", "title": "The medical man and the Constitution.", "content": "The medical man and the Constitution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994306"}
{"pmid": "20994307", "title": "Pulmonary filariasis.", "content": "Pulmonary filariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994307"}
{"pmid": "20994308", "title": "Tropical eosinophilia.", "content": "Tropical eosinophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994308"}
{"pmid": "20994309", "title": "Penicillin in the treatment of histoplasmosis.", "content": "Penicillin in the treatment of histoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994309"}
{"pmid": "20994310", "title": "Death due to administration of typhus vaccine.", "content": "Death due to administration of typhus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994310"}
{"pmid": "20994311", "title": "Regional ileitis involving the ileum, cecum, ascending colon, and transverse colon.", "content": "Regional ileitis involving the ileum, cecum, ascending colon, and transverse colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994311"}
{"pmid": "20994312", "title": "Short P-R interval with prolongation of QRS complex and myocardial infarction.", "content": "Short P-R interval with prolongation of QRS complex and myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994312"}
{"pmid": "20994313", "title": "STREPTOMYCIN.", "content": "STREPTOMYCIN.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994313"}
{"pmid": "20994314", "title": "Gonococcic peritonitis of the upper part of abdomen in young women; (phrenic reaction, or subcostal syndrome of Stajano; Fitz-Hugh-Curtis syndrome); report of cases of three patients treated successfully with penicillin and a summary of the literature.", "content": "Gonococcic peritonitis of the upper part of abdomen in young women; (phrenic reaction, or subcostal syndrome of Stajano; Fitz-Hugh-Curtis syndrome); report of cases of three patients treated successfully with penicillin and a summary of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994314"}
{"pmid": "20994315", "title": "Myelofibrosis, splenomegaly and megakaryocytic myelosis.", "content": "Myelofibrosis, splenomegaly and megakaryocytic myelosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994315"}
{"pmid": "20994316", "title": "Effect of atropine on the Branham sign in arteriovenous fistula.", "content": "Effect of atropine on the Branham sign in arteriovenous fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994316"}
{"pmid": "20994317", "title": "Precordial leads in children.", "content": "Precordial leads in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994317"}
{"pmid": "20994319", "title": "Infectious mononucleosis; a consideration of the complications and preliminary report on the use of penicillin in this disease.", "content": "Infectious mononucleosis; a consideration of the complications and preliminary report on the use of penicillin in this disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994319"}
{"pmid": "20994318", "title": "Fatal mercurial poisoning following prolonged administration of mercurophylline.", "content": "Fatal mercurial poisoning following prolonged administration of mercurophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994318"}
{"pmid": "20994320", "title": "PLASMA quinacrine concentration as a function of dosage and environment.", "content": "PLASMA quinacrine concentration as a function of dosage and environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994320"}
{"pmid": "20994321", "title": "Male infertility.", "content": "Male infertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994321"}
{"pmid": "20994322", "title": "Treatment of carcinoma of the prostate by perurethral resection and stilboestrol.", "content": "Treatment of carcinoma of the prostate by perurethral resection and stilboestrol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994322"}
{"pmid": "20994323", "title": "The outbreak of smallpox in Middlesex, 1944.", "content": "The outbreak of smallpox in Middlesex, 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994323"}
{"pmid": "20994324", "title": "A case of mercurial poisoning and its treatment.", "content": "A case of mercurial poisoning and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994324"}
{"pmid": "20994325", "title": "Reiter's disease.", "content": "Reiter's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994325"}
{"pmid": "20994326", "title": "The effect of penicillin in experimental intestinal obstruction; studies on strangulated low ileal obstructions.", "content": "The effect of penicillin in experimental intestinal obstruction; studies on strangulated low ileal obstructions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994326"}
{"pmid": "20994327", "title": "Intestinal obstruction; a study of two hundred and four acute cases with reference to the possible efficacy of anti-bacterial therapy.", "content": "Intestinal obstruction; a study of two hundred and four acute cases with reference to the possible efficacy of anti-bacterial therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994327"}
{"pmid": "20994328", "title": "The location of the conscious center in the brain; the corpus striatum.", "content": "The location of the conscious center in the brain; the corpus striatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994328"}
{"pmid": "20994329", "title": "Studies on altitude tolerance; studies on normal rats; effect of repeated short exposures to reduced atmospheric pressure.", "content": "Studies on altitude tolerance; studies on normal rats; effect of repeated short exposures to reduced atmospheric pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994329"}
{"pmid": "20994330", "title": "Studies on altitude tolerance; studies on normal human subjects; effect of repeated short exposures to reduced atmospheric pressure.", "content": "Studies on altitude tolerance; studies on normal human subjects; effect of repeated short exposures to reduced atmospheric pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994330"}
{"pmid": "20994331", "title": "Combat exhaustion.", "content": "Combat exhaustion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994331"}
{"pmid": "20994332", "title": "Prostatitis.", "content": "Prostatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994332"}
{"pmid": "20994333", "title": "Ethyl-norepinephrine, a new drug for symptomatic relief of bronchial asthma.", "content": "Ethyl-norepinephrine, a new drug for symptomatic relief of bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994333"}
{"pmid": "20994334", "title": "OBSTETRIC case report.", "content": "OBSTETRIC case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994334"}
{"pmid": "20994335", "title": "DOCTOR as an artist.", "content": "DOCTOR as an artist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994335"}
{"pmid": "20994337", "title": "Modern concepts of intestinal infection.", "content": "Modern concepts of intestinal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994337"}
{"pmid": "20994336", "title": "The treatment of some gastro-intestinal disturbances.", "content": "The treatment of some gastro-intestinal disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994336"}
{"pmid": "20994338", "title": "Some adjuvant measures in intestinal surgery.", "content": "Some adjuvant measures in intestinal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994338"}
{"pmid": "20994339", "title": "Anterior resection for malignant lesions of the upper part of the rectum and lower part of the sigmoid.", "content": "Anterior resection for malignant lesions of the upper part of the rectum and lower part of the sigmoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994339"}
{"pmid": "20994340", "title": "Present conception of endometriosis and its treatment.", "content": "Present conception of endometriosis and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994340"}
{"pmid": "20994342", "title": "A warning concerning the use of curare in convulsive shock treatment of patients with psychiatric disorders who may have myasthenia gravis.", "content": "A warning concerning the use of curare in convulsive shock treatment of patients with psychiatric disorders who may have myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994342"}
{"pmid": "20994343", "title": "The late recurrences of malignant disease.", "content": "The late recurrences of malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994343"}
{"pmid": "20994341", "title": "The pathologic significance of the ductus arteriosus; its relation to the process of arteriosclerosis.", "content": "The pathologic significance of the ductus arteriosus; its relation to the process of arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994341"}
{"pmid": "20994344", "title": "Research in nutrition; importance to the public health.", "content": "Research in nutrition; importance to the public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994344"}
{"pmid": "20994345", "title": "The influence of dietary factors on the resistance of rats to carbon tetrachloride.", "content": "The influence of dietary factors on the resistance of rats to carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994345"}
{"pmid": "20994346", "title": "The migrainous personality; an essential feature of the disease.", "content": "The migrainous personality; an essential feature of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994346"}
{"pmid": "20994347", "title": "Rabies; a general consideration.", "content": "Rabies; a general consideration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994347"}
{"pmid": "20994348", "title": "The surgical pathology of peptic ulcer and gastric carcinoma.", "content": "The surgical pathology of peptic ulcer and gastric carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994348"}
{"pmid": "20994350", "title": "Some serological aspects of infectious mononucleosis with special reference to the use of agglutinin-absorption tests in diagnosis.", "content": "Some serological aspects of infectious mononucleosis with special reference to the use of agglutinin-absorption tests in diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994350"}
{"pmid": "20994349", "title": "The use of isotopes in biology.", "content": "The use of isotopes in biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994349"}
{"pmid": "20994351", "title": "Studies on phagocytosis.", "content": "Studies on phagocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994351"}
{"pmid": "20994352", "title": "Gastroscopy.", "content": "Gastroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994352"}
{"pmid": "20994353", "title": "Anterior rupture of a cervical intervertebral disc.", "content": "Anterior rupture of a cervical intervertebral disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994353"}
{"pmid": "20994354", "title": "Fatal case of burns associated with massive gastric haemorrhage.", "content": "Fatal case of burns associated with massive gastric haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994354"}
{"pmid": "20994355", "title": "Blood transfusion.", "content": "Blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994355"}
{"pmid": "20994356", "title": "Studies in the mechanics of synovial joints; displacements on articular surfaces and the significance of saddle joints.", "content": "Studies in the mechanics of synovial joints; displacements on articular surfaces and the significance of saddle joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994356"}
{"pmid": "20994357", "title": "An investigation of the human placenta for pressor substance.", "content": "An investigation of the human placenta for pressor substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994357"}
{"pmid": "20994358", "title": "Acute rickets.", "content": "Acute rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994358"}
{"pmid": "20994359", "title": "Osteitis deformans.", "content": "Osteitis deformans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994359"}
{"pmid": "20994360", "title": "Congenital aortic stenosis.", "content": "Congenital aortic stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994360"}
{"pmid": "20994361", "title": "Congenital pulmonary stenosis.", "content": "Congenital pulmonary stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994361"}
{"pmid": "20994362", "title": "Ophthalmology's postwar responsibilities and opportunities.", "content": "Ophthalmology's postwar responsibilities and opportunities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994362"}
{"pmid": "20994363", "title": "Dynamic posture.", "content": "Dynamic posture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994363"}
{"pmid": "20994364", "title": "Endometriosis in youth.", "content": "Endometriosis in youth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994364"}
{"pmid": "20994365", "title": "Multiple Perthes' test for segmental occlusion of the deep veins.", "content": "Multiple Perthes' test for segmental occlusion of the deep veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994365"}
{"pmid": "20994366", "title": "Herpes simplex encephalitis.", "content": "Herpes simplex encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994366"}
{"pmid": "20994367", "title": "INFANTILE paralysis, or acute poliomyelitis; a brief primer of the disease and its treatment.", "content": "INFANTILE paralysis, or acute poliomyelitis; a brief primer of the disease and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994367"}
{"pmid": "20994368", "title": "Renal damage due to ischemic muscle necrosis.", "content": "Renal damage due to ischemic muscle necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994368"}
{"pmid": "20994369", "title": "WORLD Health Organization Charter.", "content": "WORLD Health Organization Charter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994369"}
{"pmid": "20994370", "title": "Preventive psychiatry; an epidemiologic approach.", "content": "Preventive psychiatry; an epidemiologic approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994370"}
{"pmid": "20994371", "title": "Electrocardiography in hypertension; study of patients subjected to lunbodorsal splanchnicectomy.", "content": "Electrocardiography in hypertension; study of patients subjected to lunbodorsal splanchnicectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994371"}
{"pmid": "20994372", "title": "The adequate treatment of gonorrhea.", "content": "The adequate treatment of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994372"}
{"pmid": "20994374", "title": "Brucellosis; advances in diagnosis and treatment.", "content": "Brucellosis; advances in diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994374"}
{"pmid": "20994373", "title": "Bile physiology and therapy.", "content": "Bile physiology and therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994373"}
{"pmid": "20994375", "title": "Tularemia acquired from the pheasant.", "content": "Tularemia acquired from the pheasant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994375"}
{"pmid": "20994376", "title": "Hyperthyroidism in pregnancy treated with thiouracil.", "content": "Hyperthyroidism in pregnancy treated with thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994376"}
{"pmid": "20994377", "title": "Reactions of monkeys to experimentally induced influenza virus A infection; an analysis of the relative rôles of humoral and cellular immunity under conditions of optimal or deficient nutrition.", "content": "Reactions of monkeys to experimentally induced influenza virus A infection; an analysis of the relative rôles of humoral and cellular immunity under conditions of optimal or deficient nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994377"}
{"pmid": "20994378", "title": "Type-specific protection and immunity following intranasal inoculation of monkeys with group A hemolytic streptococci.", "content": "Type-specific protection and immunity following intranasal inoculation of monkeys with group A hemolytic streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994378"}
{"pmid": "20994379", "title": "Preparation and properties of Shiga toxin and toxoid.", "content": "Preparation and properties of Shiga toxin and toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994379"}
{"pmid": "20994380", "title": "The fate of injected particulate antigens in relation to the formation of antibodies.", "content": "The fate of injected particulate antigens in relation to the formation of antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994380"}
{"pmid": "20994381", "title": "The specificity of serological precipitation.", "content": "The specificity of serological precipitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994381"}
{"pmid": "20994382", "title": "Effect of in vitro cultivation on the pathogenicity of West Nile virus.", "content": "Effect of in vitro cultivation on the pathogenicity of West Nile virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994382"}
{"pmid": "20994383", "title": "Van Slyke's urea clearance test in Indians in health and disease.", "content": "Van Slyke's urea clearance test in Indians in health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994383"}
{"pmid": "20994384", "title": "Some observations on cases of ascites in Hyderabad-Deccan; ascites associated with cirrhosis of the liver.", "content": "Some observations on cases of ascites in Hyderabad-Deccan; ascites associated with cirrhosis of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994384"}
{"pmid": "20994385", "title": "Public health and post-war reconstruction; with special reference to the United Provinces.", "content": "Public health and post-war reconstruction; with special reference to the United Provinces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994385"}
{"pmid": "20994386", "title": "Snake-bite.", "content": "Snake-bite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994386"}
{"pmid": "20994387", "title": "Some advances in medical treatment.", "content": "Some advances in medical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994387"}
{"pmid": "20994388", "title": "Psychoneuroses and World War II.", "content": "Psychoneuroses and World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994388"}
{"pmid": "20994389", "title": "The development of the Army Medical Department.", "content": "The development of the Army Medical Department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994389"}
{"pmid": "20994390", "title": "Some common urologic complications following abdominal surgery.", "content": "Some common urologic complications following abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994390"}
{"pmid": "20994391", "title": "The tumult in medicine; a psychosomatic analysis.", "content": "The tumult in medicine; a psychosomatic analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994391"}
{"pmid": "20994392", "title": "Visualization of a traumatic popliteal aneurysm before and after operation.", "content": "Visualization of a traumatic popliteal aneurysm before and after operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994392"}
{"pmid": "20994393", "title": "The etiology of convulsions.", "content": "The etiology of convulsions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994393"}
{"pmid": "20994394", "title": "Treatment of epilepsy in children with sodium dilantin.", "content": "Treatment of epilepsy in children with sodium dilantin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994394"}
{"pmid": "20994395", "title": "Observations of electroencephalic patterns in convulsive disorders of suspected endocrine origin.", "content": "Observations of electroencephalic patterns in convulsive disorders of suspected endocrine origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994395"}
{"pmid": "20994396", "title": "Anti-histamine agents.", "content": "Anti-histamine agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994396"}
{"pmid": "20994397", "title": "Hot weather pediatrics.", "content": "Hot weather pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994397"}
{"pmid": "20994398", "title": "Amenorrhea, its causes and treatment.", "content": "Amenorrhea, its causes and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994398"}
{"pmid": "20994399", "title": "The influence of the mind in producing health and disease.", "content": "The influence of the mind in producing health and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994399"}
{"pmid": "20994400", "title": "Pruritus ani.", "content": "Pruritus ani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994400"}
{"pmid": "20994401", "title": "Surgery of sympathetic nervous system.", "content": "Surgery of sympathetic nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994401"}
{"pmid": "20994402", "title": "The neglected patient.", "content": "The neglected patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994402"}
{"pmid": "20994403", "title": "Practical points in the diagnosis and treatment of squint in children.", "content": "Practical points in the diagnosis and treatment of squint in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994403"}
{"pmid": "20994405", "title": "Contusion injuries of the globe.", "content": "Contusion injuries of the globe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994405"}
{"pmid": "20994404", "title": "The causes and distribution of blindness in Kentucky among recipients of aid to the needy blind.", "content": "The causes and distribution of blindness in Kentucky among recipients of aid to the needy blind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994404"}
{"pmid": "20994406", "title": "Recent developments in the use of penicillin and sulfonamides in the treatment of diseases of the ear, nose and throat.", "content": "Recent developments in the use of penicillin and sulfonamides in the treatment of diseases of the ear, nose and throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994406"}
{"pmid": "20994407", "title": "Treatment of dendritic keratitis.", "content": "Treatment of dendritic keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994407"}
{"pmid": "20994408", "title": "Catarrhal deafness.", "content": "Catarrhal deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994408"}
{"pmid": "20994409", "title": "Treatment in psychiatry.", "content": "Treatment in psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994409"}
{"pmid": "20994410", "title": "Recent trends in the therapy of liver disease.", "content": "Recent trends in the therapy of liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994410"}
{"pmid": "20994411", "title": "Recent advances in anesthesiology.", "content": "Recent advances in anesthesiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994411"}
{"pmid": "20994413", "title": "THE hospital library.", "content": "THE hospital library.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994413"}
{"pmid": "20994412", "title": "Virus pneumonia: differentiation from pulmonary tuberculosis.", "content": "Virus pneumonia: differentiation from pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994412"}
{"pmid": "20994414", "title": "The surgery of jaundice.", "content": "The surgery of jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994414"}
{"pmid": "20994415", "title": "Pages from a military psychiatric notebook.", "content": "Pages from a military psychiatric notebook.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994415"}
{"pmid": "20994416", "title": "Detachment of the retina.", "content": "Detachment of the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994416"}
{"pmid": "20994417", "title": "Psychology and some applications.", "content": "Psychology and some applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994417"}
{"pmid": "20994418", "title": "Psychology in the Australian Army.", "content": "Psychology in the Australian Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994418"}
{"pmid": "20994419", "title": "Quinine amaurosis.", "content": "Quinine amaurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994419"}
{"pmid": "20994420", "title": "Report of a case of true infective abacterial pyuria.", "content": "Report of a case of true infective abacterial pyuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994420"}
{"pmid": "20994421", "title": "Intracranial haemorrhage in the newborn.", "content": "Intracranial haemorrhage in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994421"}
{"pmid": "20994422", "title": "Spinal anaesthesia amd chloroform; a comparison of mortality.", "content": "Spinal anaesthesia amd chloroform; a comparison of mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994422"}
{"pmid": "20994424", "title": "The behaviour of New Guinea strains of Plasmodium falciparum and Plasmodium vivax when cultivated in vitro.", "content": "The behaviour of New Guinea strains of Plasmodium falciparum and Plasmodium vivax when cultivated in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994424"}
{"pmid": "20994423", "title": "Some complications and sequelae of the prophylactic inoculations.", "content": "Some complications and sequelae of the prophylactic inoculations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994423"}
{"pmid": "20994425", "title": "Genito-urinary disorders occurring in Singapore prisoner-of-war camp, with special reference to polyuria and non-specific inflammations.", "content": "Genito-urinary disorders occurring in Singapore prisoner-of-war camp, with special reference to polyuria and non-specific inflammations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994425"}
{"pmid": "20994426", "title": "Profuse or irregular menstrual periods in young women; a practical programme of treatment.", "content": "Profuse or irregular menstrual periods in young women; a practical programme of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994426"}
{"pmid": "20994427", "title": "Advances in the surgery of hand infections, with special reference to pad infections.", "content": "Advances in the surgery of hand infections, with special reference to pad infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994427"}
{"pmid": "20994428", "title": "The place of surgery in diseases of the chest.", "content": "The place of surgery in diseases of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994428"}
{"pmid": "20994429", "title": "The distribution of fluorine in potable waters in New South Wales and Tasmania.", "content": "The distribution of fluorine in potable waters in New South Wales and Tasmania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994429"}
{"pmid": "20994430", "title": "An acquired haemorrhagic disease in a female due to an inhibitor of blood coagulation.", "content": "An acquired haemorrhagic disease in a female due to an inhibitor of blood coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994430"}
{"pmid": "20994431", "title": "Report of a case of osteogenic fibroma of the skull.", "content": "Report of a case of osteogenic fibroma of the skull.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994431"}
{"pmid": "20994432", "title": "Serious infections of the hand and penicillin.", "content": "Serious infections of the hand and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994432"}
{"pmid": "20994433", "title": "A large myoma.", "content": "A large myoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994433"}
{"pmid": "20994434", "title": "RESULTS of war-time research.", "content": "RESULTS of war-time research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994434"}
{"pmid": "20994435", "title": "Xanthoma diabeticorum.", "content": "Xanthoma diabeticorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994435"}
{"pmid": "20994436", "title": "Newer concepts in child psychiatry.", "content": "Newer concepts in child psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994436"}
{"pmid": "20994437", "title": "The treatment of pyogenic infections of the central nervous system with intraspinal penicillin; apparent damage to cauda equina and spinal cord.", "content": "The treatment of pyogenic infections of the central nervous system with intraspinal penicillin; apparent damage to cauda equina and spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994437"}
{"pmid": "20994438", "title": "Myasthenia gravis; oto-laryngological aspects.", "content": "Myasthenia gravis; oto-laryngological aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994438"}
{"pmid": "20994439", "title": "Personality factors in compensation cases.", "content": "Personality factors in compensation cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994439"}
{"pmid": "20994440", "title": "The neuropsychiatric training program at the Medical Branch, University of Texas.", "content": "The neuropsychiatric training program at the Medical Branch, University of Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994440"}
{"pmid": "20994441", "title": "Chronic or latent malaria and its sequelae; hay fever and other allergic conditions.", "content": "Chronic or latent malaria and its sequelae; hay fever and other allergic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994441"}
{"pmid": "20994442", "title": "Lithogenesis and hypovitaminosis.", "content": "Lithogenesis and hypovitaminosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994442"}
{"pmid": "20994443", "title": "Disturbed personality due to sexual neurasthenia; its management and treatment.", "content": "Disturbed personality due to sexual neurasthenia; its management and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994443"}
{"pmid": "20994444", "title": "Roentgen therapy of the arthritides and ligamentous, tendinous and bursal inflammations.", "content": "Roentgen therapy of the arthritides and ligamentous, tendinous and bursal inflammations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994444"}
{"pmid": "20994445", "title": "Gold salts in the treatment of rheumatoid arthritis; a report on 150 additional cases.", "content": "Gold salts in the treatment of rheumatoid arthritis; a report on 150 additional cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994445"}
{"pmid": "20994446", "title": "The action of hormones on varicose veins in pregnancy.", "content": "The action of hormones on varicose veins in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994446"}
{"pmid": "20994447", "title": "The use of medicine in the behavior disorders.", "content": "The use of medicine in the behavior disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994447"}
{"pmid": "20994448", "title": "A case of ectopic pregnancy.", "content": "A case of ectopic pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994448"}
{"pmid": "20994449", "title": "The Women's Medical College of Chicago.", "content": "The Women's Medical College of Chicago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994449"}
{"pmid": "20994451", "title": "Experiences in the treatment of open cranial wounds.", "content": "Experiences in the treatment of open cranial wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994451"}
{"pmid": "20994450", "title": "Common minor surgical conditions of the ano-rectal region.", "content": "Common minor surgical conditions of the ano-rectal region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994450"}
{"pmid": "20994453", "title": "Influenzal meningitis.", "content": "Influenzal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994453"}
{"pmid": "20994452", "title": "Early symptoms and diagnosis of cancer of the colon.", "content": "Early symptoms and diagnosis of cancer of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994452"}
{"pmid": "20994454", "title": "Progressive exophthalmos probably due to pituitary hyperfunction.", "content": "Progressive exophthalmos probably due to pituitary hyperfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994454"}
{"pmid": "20994455", "title": "A case of band keratitis.", "content": "A case of band keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994455"}
{"pmid": "20994456", "title": "A case of traumatic occlusion of the central retinal artery.", "content": "A case of traumatic occlusion of the central retinal artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994456"}
{"pmid": "20994457", "title": "A case report of metastatic endophthalmitis.", "content": "A case report of metastatic endophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994457"}
{"pmid": "20994458", "title": "Acute labyrinthitis following radical mastoid operation.", "content": "Acute labyrinthitis following radical mastoid operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994458"}
{"pmid": "20994459", "title": "Pansinusitis with screw worm infestation.", "content": "Pansinusitis with screw worm infestation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994459"}
{"pmid": "20994460", "title": "The surgical treatment of hernia.", "content": "The surgical treatment of hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994460"}
{"pmid": "20994461", "title": "Pulmonary hypertension.", "content": "Pulmonary hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994461"}
{"pmid": "20994462", "title": "The relation of hypertension to vascular disease.", "content": "The relation of hypertension to vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994462"}
{"pmid": "20994463", "title": "Gastric polyposis.", "content": "Gastric polyposis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994463"}
{"pmid": "20994464", "title": "Clinical comparison of the cardiac glycosides.", "content": "Clinical comparison of the cardiac glycosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994464"}
{"pmid": "20994465", "title": "Primary atypical pneumonia.", "content": "Primary atypical pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994465"}
{"pmid": "20994466", "title": "Endocrine features and treatment of chronic cystic mastitis and their relation to infertility.", "content": "Endocrine features and treatment of chronic cystic mastitis and their relation to infertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994466"}
{"pmid": "20994467", "title": "Practical considerations in the conservative treatment of thrombophlebitis.", "content": "Practical considerations in the conservative treatment of thrombophlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994467"}
{"pmid": "20994468", "title": "Surgical management of thrombosis and thrombophlebitis with discussion of vein resection.", "content": "Surgical management of thrombosis and thrombophlebitis with discussion of vein resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994468"}
{"pmid": "20994469", "title": "Putrid lung abscess superimposed upon a pulmonary infarct in a noncardiac patient.", "content": "Putrid lung abscess superimposed upon a pulmonary infarct in a noncardiac patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994469"}
{"pmid": "20994470", "title": "Dried plasma and whole blood therapy.", "content": "Dried plasma and whole blood therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994470"}
{"pmid": "20994471", "title": "PAULUS VAN DER BEECK, Brooklyn's first surgeon.", "content": "PAULUS VAN DER BEECK, Brooklyn's first surgeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994471"}
{"pmid": "20994472", "title": "Four-dimensional medicine.", "content": "Four-dimensional medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994472"}
{"pmid": "20994473", "title": "Extracts of information on the basic science law.", "content": "Extracts of information on the basic science law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994473"}
{"pmid": "20994474", "title": "The surgical management of acute massive hemorrhage from peptic ulcer.", "content": "The surgical management of acute massive hemorrhage from peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994474"}
{"pmid": "20994476", "title": "Biochemic imbalance in surgery.", "content": "Biochemic imbalance in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994476"}
{"pmid": "20994475", "title": "Vascular complications; pulmonary embolism.", "content": "Vascular complications; pulmonary embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994475"}
{"pmid": "20994477", "title": "Psychiatric disease amenable to care in a general hospital.", "content": "Psychiatric disease amenable to care in a general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994477"}
{"pmid": "20994478", "title": "Meningitis (nontuberculous) in children.", "content": "Meningitis (nontuberculous) in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994478"}
{"pmid": "20994480", "title": "Clinical application of liver function tests.", "content": "Clinical application of liver function tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994480"}
{"pmid": "20994479", "title": "Tyrothricin, a review of selected literature on the subject.", "content": "Tyrothricin, a review of selected literature on the subject.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994479"}
{"pmid": "20994483", "title": "Surgical management of carcinoma of the colon and rectum.", "content": "Surgical management of carcinoma of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994483"}
{"pmid": "20994485", "title": "The conservation of pulmonary function in the treatment of chest casualties.", "content": "The conservation of pulmonary function in the treatment of chest casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994485"}
{"pmid": "20994484", "title": "Gastritis among Navy personnel.", "content": "Gastritis among Navy personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994484"}
{"pmid": "20994486", "title": "What we expect from the American Medical Association and its Council on Medical Service and Public Relations.", "content": "What we expect from the American Medical Association and its Council on Medical Service and Public Relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994486"}
{"pmid": "20994487", "title": "Amebiasis.", "content": "Amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994487"}
{"pmid": "20994488", "title": "Reconstruction of the shoulder.", "content": "Reconstruction of the shoulder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994488"}
{"pmid": "20994489", "title": "Delayed rupture of the spleen.", "content": "Delayed rupture of the spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994489"}
{"pmid": "20994490", "title": "Coccidioidal meningitis.", "content": "Coccidioidal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994490"}
{"pmid": "20994491", "title": "Some properties of experimental electroshock seizures.", "content": "Some properties of experimental electroshock seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994491"}
{"pmid": "20994493", "title": "Prefrontal lobotomy; factors influencing prognosis.", "content": "Prefrontal lobotomy; factors influencing prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994493"}
{"pmid": "20994492", "title": "The effect of stilbestrol on the testis and breast of patients treated for carcinoma of the prostate gland.", "content": "The effect of stilbestrol on the testis and breast of patients treated for carcinoma of the prostate gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994492"}
{"pmid": "20994494", "title": "Discussion on the stethoscope versus x-rays.", "content": "Discussion on the stethoscope versus x-rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994494"}
{"pmid": "20994496", "title": "Infectious hepatitis.", "content": "Infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994496"}
{"pmid": "20994495", "title": "Cholesterol levels in various diseases and the effects of decholesterizing agents.", "content": "Cholesterol levels in various diseases and the effects of decholesterizing agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994495"}
{"pmid": "20994497", "title": "War wounds of the liver.", "content": "War wounds of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994497"}
{"pmid": "20994498", "title": "Treatment of compound fractures of the long bones.", "content": "Treatment of compound fractures of the long bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994498"}
{"pmid": "20994499", "title": "The use of thromboplastin fixation in skin grafting and wound healing.", "content": "The use of thromboplastin fixation in skin grafting and wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994499"}
{"pmid": "20994500", "title": "Outlook for infants receiving anti-Rh agglutinins from isoimmunization of mothers.", "content": "Outlook for infants receiving anti-Rh agglutinins from isoimmunization of mothers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994500"}
{"pmid": "20994502", "title": "A simple technic for the closure of the cataract incision.", "content": "A simple technic for the closure of the cataract incision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994502"}
{"pmid": "20994501", "title": "The use of fine cotton sutures in episiotomy repairs.", "content": "The use of fine cotton sutures in episiotomy repairs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994501"}
{"pmid": "20994503", "title": "Ulcerative colitis with perforation in a newborn.", "content": "Ulcerative colitis with perforation in a newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994503"}
{"pmid": "20994504", "title": "Tin mining and silicosis in Cornwall.", "content": "Tin mining and silicosis in Cornwall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994504"}
{"pmid": "20994505", "title": "Residual iodized oil following bronchography.", "content": "Residual iodized oil following bronchography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994505"}
{"pmid": "20994506", "title": "Pulmonary tuberculosis in African native troops.", "content": "Pulmonary tuberculosis in African native troops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994506"}
{"pmid": "20994507", "title": "The examination of the sputum and pleural fluid in the diagnosis of malignant disease of the lung.", "content": "The examination of the sputum and pleural fluid in the diagnosis of malignant disease of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994507"}
{"pmid": "20994508", "title": "Anoxia and the central nervous system.", "content": "Anoxia and the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994508"}
{"pmid": "20994512", "title": "The possibility for post-graduate education in the small hospital.", "content": "The possibility for post-graduate education in the small hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994512"}
{"pmid": "20994513", "title": "Modern therapy of trigeminal neuralgia.", "content": "Modern therapy of trigeminal neuralgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994513"}
{"pmid": "20994514", "title": "Histoplasmosis; report of case with autopsy.", "content": "Histoplasmosis; report of case with autopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994514"}
{"pmid": "20994515", "title": "The early years of the Kjeldahl method to determine nitrogen.", "content": "The early years of the Kjeldahl method to determine nitrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994515"}
{"pmid": "20994516", "title": "Surface potentials and peripheral nerve injury, a clinical test.", "content": "Surface potentials and peripheral nerve injury, a clinical test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994516"}
{"pmid": "20994518", "title": "Psychology and the scientific fallacy.", "content": "Psychology and the scientific fallacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994518"}
{"pmid": "20994517", "title": "Thiourea and related compounds in the treatment of hyperthyroidism.", "content": "Thiourea and related compounds in the treatment of hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994517"}
{"pmid": "20994520", "title": "The relationship between the military loss resulting from a casualty and the days lost from active duty.", "content": "The relationship between the military loss resulting from a casualty and the days lost from active duty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994520"}
{"pmid": "20994519", "title": "Dermatoglyphics; significant patternings of the body surface.", "content": "Dermatoglyphics; significant patternings of the body surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994519"}
{"pmid": "20994521", "title": "A note on the incidence of diabetes mellitus in fractures of the hip.", "content": "A note on the incidence of diabetes mellitus in fractures of the hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994521"}
{"pmid": "20994523", "title": "The clinical aspects of evaluating analgesic agents; with notes on the safety of morphine.", "content": "The clinical aspects of evaluating analgesic agents; with notes on the safety of morphine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994523"}
{"pmid": "20994522", "title": "A necrotizing disease in rabbits affecting fatty and muscular tissues; analogies with the Weber-Christian disease of humans.", "content": "A necrotizing disease in rabbits affecting fatty and muscular tissues; analogies with the Weber-Christian disease of humans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994522"}
{"pmid": "20994524", "title": "Studies on resistance to antibiotics; the action of penicillin on some gram-positive and gram-negative organisms and its potentiation by various inhibitors.", "content": "Studies on resistance to antibiotics; the action of penicillin on some gram-positive and gram-negative organisms and its potentiation by various inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994524"}
{"pmid": "20994525", "title": "A history; United States Naval Hospital, Norman, Oklahoma.", "content": "A history; United States Naval Hospital, Norman, Oklahoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994525"}
{"pmid": "20994526", "title": "Nerve regeneration; observations on motor and sensory recovery in a case of injury to the radial nerve.", "content": "Nerve regeneration; observations on motor and sensory recovery in a case of injury to the radial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994526"}
{"pmid": "20994527", "title": "Some aspects of personnel research in North America.", "content": "Some aspects of personnel research in North America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994527"}
{"pmid": "20994528", "title": "The health of the Women's Royal Naval Service.", "content": "The health of the Women's Royal Naval Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994528"}
{"pmid": "20994529", "title": "The Maldive Islands and their inhabitants.", "content": "The Maldive Islands and their inhabitants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994529"}
{"pmid": "20994530", "title": "Some problems of epilepsy in the Royal Navy.", "content": "Some problems of epilepsy in the Royal Navy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994530"}
{"pmid": "20994532", "title": "Concomitant allergy and dolicho-megacolon in father and daughter.", "content": "Concomitant allergy and dolicho-megacolon in father and daughter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994532"}
{"pmid": "20994531", "title": "Psychiatry in the Levant.", "content": "Psychiatry in the Levant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994531"}
{"pmid": "20994534", "title": "Blackwater fever.", "content": "Blackwater fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994534"}
{"pmid": "20994533", "title": "Sulphonamide resistant pneumococcal loculated empyema treated with penicillin.", "content": "Sulphonamide resistant pneumococcal loculated empyema treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994533"}
{"pmid": "20994535", "title": "Shock.", "content": "Shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994535"}
{"pmid": "20994542", "title": "The utilisation of by-products of the shark liver oil industry.", "content": "The utilisation of by-products of the shark liver oil industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994542"}
{"pmid": "20994543", "title": "Chemistry of kurchi seeds; isolation of the bromide of a linoleo-dilinolenin from the fatty oil.", "content": "Chemistry of kurchi seeds; isolation of the bromide of a linoleo-dilinolenin from the fatty oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994543"}
{"pmid": "20994544", "title": "The chromosome number in Torula utilis.", "content": "The chromosome number in Torula utilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994544"}
{"pmid": "20994545", "title": "The micro-organisms in Melophagus ovinus.", "content": "The micro-organisms in Melophagus ovinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994545"}
{"pmid": "20994546", "title": "Tamarind seed pectin.", "content": "Tamarind seed pectin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994546"}
{"pmid": "20994547", "title": "Does potassium stimulate by releasing acetylcholine?", "content": "Does potassium stimulate by releasing acetylcholine?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994547"}
{"pmid": "20994549", "title": "Civilization and the pursuit of knowledge.", "content": "Civilization and the pursuit of knowledge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994549"}
{"pmid": "20994548", "title": "Some new hosts of Sclerotinia sclerotiorum (Lib.) de Bary.", "content": "Some new hosts of Sclerotinia sclerotiorum (Lib.) de Bary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994548"}
{"pmid": "20994550", "title": "Defence against the atomic bomb.", "content": "Defence against the atomic bomb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994550"}
{"pmid": "20994551", "title": "Life and the second law of thermodynamics.", "content": "Life and the second law of thermodynamics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994551"}
{"pmid": "20994552", "title": "Fission products of U235.", "content": "Fission products of U235.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994552"}
{"pmid": "20994553", "title": "Giant nerve fibre of Myxicola infundibulum (Grube).", "content": "Giant nerve fibre of Myxicola infundibulum (Grube).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994553"}
{"pmid": "20994554", "title": "A new route to 7-dehydrocholesterol, provitamin D3.", "content": "A new route to 7-dehydrocholesterol, provitamin D3.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994554"}
{"pmid": "20994555", "title": "Antimalarial drugs of the indigenous materia medica of China and India.", "content": "Antimalarial drugs of the indigenous materia medica of China and India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994555"}
{"pmid": "20994556", "title": "Inequalities in adult capacity; from military data.", "content": "Inequalities in adult capacity; from military data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994556"}
{"pmid": "20994557", "title": "The concentration of 39K and 41K by balanced ion migration in a counterflowing electrolyte.", "content": "The concentration of 39K and 41K by balanced ion migration in a counterflowing electrolyte.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994557"}
{"pmid": "20994558", "title": "Determination of total body water and solids with isotopes.", "content": "Determination of total body water and solids with isotopes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994558"}
{"pmid": "20994559", "title": "The growth response of Tetrahymena geleii W to folic acid and to the Streptococcus lactis R factor.", "content": "The growth response of Tetrahymena geleii W to folic acid and to the Streptococcus lactis R factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994559"}
{"pmid": "20994560", "title": "Coordination of cancer research.", "content": "Coordination of cancer research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994560"}
{"pmid": "20994561", "title": "Human breast cancer and the milk factor.", "content": "Human breast cancer and the milk factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994561"}
{"pmid": "20994563", "title": "A new classification system for chemical compounds.", "content": "A new classification system for chemical compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994563"}
{"pmid": "20994562", "title": "Scientific publication as affected by war and politics.", "content": "Scientific publication as affected by war and politics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994562"}
{"pmid": "20994564", "title": "On the preparation of extensive bibliographies.", "content": "On the preparation of extensive bibliographies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994564"}
{"pmid": "20994565", "title": "Punch cards for indexing scientific data.", "content": "Punch cards for indexing scientific data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994565"}
{"pmid": "20994566", "title": "A comment on discoveries in the vitamin A field.", "content": "A comment on discoveries in the vitamin A field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994566"}
{"pmid": "20994567", "title": "The incidence of feeblemindedness in the cerebral palsied.", "content": "The incidence of feeblemindedness in the cerebral palsied.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994567"}
{"pmid": "20994569", "title": "Practical implications of the endogenous-exogenous classification of mental defectives.", "content": "Practical implications of the endogenous-exogenous classification of mental defectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994569"}
{"pmid": "20994570", "title": "The medical concept of feeble-mindedness.", "content": "The medical concept of feeble-mindedness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994570"}
{"pmid": "20994568", "title": "Classroom observation for learning difficulties of high-grade mentally defective children with mental ages below six years.", "content": "Classroom observation for learning difficulties of high-grade mentally defective children with mental ages below six years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994568"}
{"pmid": "20994571", "title": "In-service training for employees of institutions for mental defectives.", "content": "In-service training for employees of institutions for mental defectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994571"}
{"pmid": "20994572", "title": "A music program in a residential school for higher grade mental defectives.", "content": "A music program in a residential school for higher grade mental defectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994572"}
{"pmid": "20994573", "title": "Recreational education and social integration in an institution for the mentally deficient.", "content": "Recreational education and social integration in an institution for the mentally deficient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994573"}
{"pmid": "20994574", "title": "Survey of a scouting program in a school for mental defectives.", "content": "Survey of a scouting program in a school for mental defectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994574"}
{"pmid": "20994575", "title": "The Cottage Activity Teaching Program at the Polk State School from October, 1944 to January, 1945.", "content": "The Cottage Activity Teaching Program at the Polk State School from October, 1944 to January, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994575"}
{"pmid": "20994576", "title": "A survey of the educational department of the Polk State School.", "content": "A survey of the educational department of the Polk State School.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994576"}
{"pmid": "20994577", "title": "The treatment of psychiatric disorders due to combat by means of a group therapy program and insulin in sub-shock doses.", "content": "The treatment of psychiatric disorders due to combat by means of a group therapy program and insulin in sub-shock doses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994577"}
{"pmid": "20994579", "title": "PSYCHIATRY nomenclature; psychiatric disorders and reactions: definitions and manner of recording.", "content": "PSYCHIATRY nomenclature; psychiatric disorders and reactions: definitions and manner of recording.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994579"}
{"pmid": "20994578", "title": "Use of the Bellevue-Wechsler scale in clinical psychiatry; with particular reference to cases with brain damage.", "content": "Use of the Bellevue-Wechsler scale in clinical psychiatry; with particular reference to cases with brain damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994578"}
{"pmid": "20994580", "title": "Syphilitic meningitis with negative blood and spinal fluid serology, report of a rare syndrome.", "content": "Syphilitic meningitis with negative blood and spinal fluid serology, report of a rare syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994580"}
{"pmid": "20994581", "title": "Two cases of brain tumor.", "content": "Two cases of brain tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994581"}
{"pmid": "20994582", "title": "A case of encephalomalacia of the cerebellum and temporosphenoidal lobe.", "content": "A case of encephalomalacia of the cerebellum and temporosphenoidal lobe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994582"}
{"pmid": "20994583", "title": "Traumatic hematomyelia with unusual features.", "content": "Traumatic hematomyelia with unusual features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994583"}
{"pmid": "20994585", "title": "The myelinization of the central nervous system of Natrix sipedon.", "content": "The myelinization of the central nervous system of Natrix sipedon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994585"}
{"pmid": "20994584", "title": "Penicillin in neurosyphilis.", "content": "Penicillin in neurosyphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994584"}
{"pmid": "20994586", "title": "Some lessons of wartime psychiatry.", "content": "Some lessons of wartime psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994586"}
{"pmid": "20994587", "title": "Pioneer work with cerebral palsy.", "content": "Pioneer work with cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994587"}
{"pmid": "20994588", "title": "Report on an evacuation hostel in Yorkshire.", "content": "Report on an evacuation hostel in Yorkshire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994588"}
{"pmid": "20994589", "title": "Civil resettlement of ex-prisoners of war.", "content": "Civil resettlement of ex-prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994589"}
{"pmid": "20994590", "title": "The necessity for speech therapy among children; some suggestions as to methods of treatment.", "content": "The necessity for speech therapy among children; some suggestions as to methods of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994590"}
{"pmid": "20994591", "title": "FREEDOM from coercion.", "content": "FREEDOM from coercion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994591"}
{"pmid": "20994592", "title": "The tradition of force and punishment.", "content": "The tradition of force and punishment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994592"}
{"pmid": "20994593", "title": "Coercion; pathogene or therapy.", "content": "Coercion; pathogene or therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994593"}
{"pmid": "20994595", "title": "Coercive education; a menace.", "content": "Coercive education; a menace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994595"}
{"pmid": "20994594", "title": "Some thoughts on the psychopathology of coercion in child training.", "content": "Some thoughts on the psychopathology of coercion in child training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994594"}
{"pmid": "20994596", "title": "Coercion in the nursery school.", "content": "Coercion in the nursery school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994596"}
{"pmid": "20994597", "title": "Coercion as a factor in siblings rivalry.", "content": "Coercion as a factor in siblings rivalry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994597"}
{"pmid": "20994598", "title": "Emancipation of the adolescent from parental control.", "content": "Emancipation of the adolescent from parental control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994598"}
{"pmid": "20994599", "title": "The emotional background of 30 children with reading disabilities with emphasis on its coercive elements.", "content": "The emotional background of 30 children with reading disabilities with emphasis on its coercive elements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994599"}
{"pmid": "20994629", "title": "Hurried living and heart disease.", "content": "Hurried living and heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994629"}
{"pmid": "20994630", "title": "TB in industry.", "content": "TB in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994630"}
{"pmid": "20994631", "title": "The physically disabled can help themselves.", "content": "The physically disabled can help themselves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994631"}
{"pmid": "20994632", "title": "Mustard-gas burns of human eyes in World War II.", "content": "Mustard-gas burns of human eyes in World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994632"}
{"pmid": "20994633", "title": "Early ocular manifestations in the Laurence-Moon-Biedl syndrome.", "content": "Early ocular manifestations in the Laurence-Moon-Biedl syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994633"}
{"pmid": "20994634", "title": "Plastic eye implant.", "content": "Plastic eye implant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994634"}
{"pmid": "20994635", "title": "The eye examination in the differential diagnosis of the disoriented patient.", "content": "The eye examination in the differential diagnosis of the disoriented patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994635"}
{"pmid": "20994636", "title": "Ophthalmopedics.", "content": "Ophthalmopedics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994636"}
{"pmid": "20994637", "title": "The therapeutic treatment of uveitis associated with toxoplasmosis.", "content": "The therapeutic treatment of uveitis associated with toxoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994637"}
{"pmid": "20994639", "title": "Plastic-artificial-eye program, U.S. Army.", "content": "Plastic-artificial-eye program, U.S. Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994639"}
{"pmid": "20994640", "title": "Methacrylic resin implant for sunken upper lid following enucleation.", "content": "Methacrylic resin implant for sunken upper lid following enucleation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994640"}
{"pmid": "20994638", "title": "Exopthalmos caused by eosinophilic granuloma of bone.", "content": "Exopthalmos caused by eosinophilic granuloma of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994638"}
{"pmid": "20994641", "title": "Charting diplopia and muscle action.", "content": "Charting diplopia and muscle action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994641"}
{"pmid": "20994642", "title": "Streptomycin treatment of a corneal abscess caused by Escherichia coli.", "content": "Streptomycin treatment of a corneal abscess caused by Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994642"}
{"pmid": "20994643", "title": "Reconstruction of the floor of the orbit.", "content": "Reconstruction of the floor of the orbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994643"}
{"pmid": "20994644", "title": "Essential xanthomatosis with hypercholesteremia.", "content": "Essential xanthomatosis with hypercholesteremia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994644"}
{"pmid": "20994645", "title": "Round-table discussion on nutrition.", "content": "Round-table discussion on nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994645"}
{"pmid": "20994646", "title": "Malignant bilateral exophthalmos.", "content": "Malignant bilateral exophthalmos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994646"}
{"pmid": "20994647", "title": "Early malignant exophthalmos.", "content": "Early malignant exophthalmos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994647"}
{"pmid": "20994648", "title": "Congenital cataracts and high myopia.", "content": "Congenital cataracts and high myopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994648"}
{"pmid": "20994649", "title": "Cataract, ectopia lentis.", "content": "Cataract, ectopia lentis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994649"}
{"pmid": "20994650", "title": "Right lateral-rectus paralysis improved by Gifford operation.", "content": "Right lateral-rectus paralysis improved by Gifford operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994650"}
{"pmid": "20994651", "title": "Hemorrhagic glaucoma and rubeosis iridis.", "content": "Hemorrhagic glaucoma and rubeosis iridis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994651"}
{"pmid": "20994652", "title": "Exophthalmos due to retrobulbar metastasis of pulmonary carcinoma.", "content": "Exophthalmos due to retrobulbar metastasis of pulmonary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994652"}
{"pmid": "20994653", "title": "Theories concerning myopia.", "content": "Theories concerning myopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994653"}
{"pmid": "20994654", "title": "The perioptic atrophic ring and its relationships.", "content": "The perioptic atrophic ring and its relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994654"}
{"pmid": "20994655", "title": "Arabian ophthalmology.", "content": "Arabian ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994655"}
{"pmid": "20994656", "title": "Occupational therapy in eye wards.", "content": "Occupational therapy in eye wards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994656"}
{"pmid": "20994657", "title": "The use of contact corneal rings in x-ray localisation of intra-ocular foreign bodies.", "content": "The use of contact corneal rings in x-ray localisation of intra-ocular foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994657"}
{"pmid": "20994658", "title": "A case of chondroma bulbi.", "content": "A case of chondroma bulbi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994658"}
{"pmid": "20994660", "title": "Report on a case of hydrophthalmia (buph thalmos).", "content": "Report on a case of hydrophthalmia (buph thalmos).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994660"}
{"pmid": "20994659", "title": "The diagnostic and clinical value of some forms of retinal angiospasm.", "content": "The diagnostic and clinical value of some forms of retinal angiospasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994659"}
{"pmid": "20994661", "title": "An electrolysis apparatus devised for retinal detachments.", "content": "An electrolysis apparatus devised for retinal detachments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994661"}
{"pmid": "20994662", "title": "The use of individual hearing aids in a residential school for the deaf with implications for acoustic training.", "content": "The use of individual hearing aids in a residential school for the deaf with implications for acoustic training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994662"}
{"pmid": "20994663", "title": "Trends and progress in the education of the deaf and of the hard of hearing in the Chicago Public Schools.", "content": "Trends and progress in the education of the deaf and of the hard of hearing in the Chicago Public Schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994663"}
{"pmid": "20994664", "title": "A review of the Little Paper Family for 1945-1946.", "content": "A review of the Little Paper Family for 1945-1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994664"}
{"pmid": "20994665", "title": "Compensation insurance for deaf workers.", "content": "Compensation insurance for deaf workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994665"}
{"pmid": "20994666", "title": "Summaries from appraisal of the silent reading abilities of acoustically handicapped children.", "content": "Summaries from appraisal of the silent reading abilities of acoustically handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994666"}
{"pmid": "20994667", "title": "Selection of hearing aids.", "content": "Selection of hearing aids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994667"}
{"pmid": "20994668", "title": "Office study of cilia.", "content": "Office study of cilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994668"}
{"pmid": "20994669", "title": "Nonexperimental pathologic nasal findings in laboratory rats.", "content": "Nonexperimental pathologic nasal findings in laboratory rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994669"}
{"pmid": "20994670", "title": "Thyroxin therapy in otosclerosis.", "content": "Thyroxin therapy in otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994670"}
{"pmid": "20994671", "title": "Odontoma of the nasopharynx.", "content": "Odontoma of the nasopharynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994671"}
{"pmid": "20994672", "title": "Effect of labyrinthine reflexes on the vegetative nervous system.", "content": "Effect of labyrinthine reflexes on the vegetative nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994672"}
{"pmid": "20994673", "title": "Complications in cataract surgery.", "content": "Complications in cataract surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994673"}
{"pmid": "20994674", "title": "Bismuth subsalicylate in oil; the treatment of choice in Vincent's angina.", "content": "Bismuth subsalicylate in oil; the treatment of choice in Vincent's angina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994674"}
{"pmid": "20994675", "title": "A new pharyngoscope; facilitating diagnosis and treatment of nasopharyngeal diseases.", "content": "A new pharyngoscope; facilitating diagnosis and treatment of nasopharyngeal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994675"}
{"pmid": "20994676", "title": "A physiological unit of accommodation.", "content": "A physiological unit of accommodation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994676"}
{"pmid": "20994677", "title": "Postoperative results in two cases of congenital choanal occlusion.", "content": "Postoperative results in two cases of congenital choanal occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994677"}
{"pmid": "20994678", "title": "Classification of strabismus.", "content": "Classification of strabismus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994678"}
{"pmid": "20994679", "title": "Use of nasal inhalers as a possible cause of otitis media.", "content": "Use of nasal inhalers as a possible cause of otitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994679"}
{"pmid": "20994680", "title": "Congenital choanal atresia.", "content": "Congenital choanal atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994680"}
{"pmid": "20994681", "title": "The repair of the depressed nasal bridge.", "content": "The repair of the depressed nasal bridge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994681"}
{"pmid": "20994682", "title": "Wounds of the mastoid process.", "content": "Wounds of the mastoid process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994682"}
{"pmid": "20994683", "title": "Labyrinthine dropsy.", "content": "Labyrinthine dropsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994683"}
{"pmid": "20994684", "title": "Use of antireticular cytotoxic serum in atrophic rhinitis (ozena).", "content": "Use of antireticular cytotoxic serum in atrophic rhinitis (ozena).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994684"}
{"pmid": "20994685", "title": "Oral penicillin in otolaryngology.", "content": "Oral penicillin in otolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994685"}
{"pmid": "20994686", "title": "A sound source for the otologist.", "content": "A sound source for the otologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994686"}
{"pmid": "20994687", "title": "Intrathoracic lesions of clinical and pathologic interest; ganglioneuroma of mediastinum; endobronchial adenoma; endobronchial and extrabronchial adenoma; total, permanent, benign, obstructive, unilateral atelectasis, cyst of mediastinum.", "content": "Intrathoracic lesions of clinical and pathologic interest; ganglioneuroma of mediastinum; endobronchial adenoma; endobronchial and extrabronchial adenoma; total, permanent, benign, obstructive, unilateral atelectasis, cyst of mediastinum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994687"}
{"pmid": "20994688", "title": "Pulmonary agenesis and hypoplasia.", "content": "Pulmonary agenesis and hypoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994688"}
{"pmid": "20994689", "title": "A fatal case of beriberi in a child in England.", "content": "A fatal case of beriberi in a child in England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994689"}
{"pmid": "20994690", "title": "Penicillin and sulphonamides in the treatment of infections in infancy.", "content": "Penicillin and sulphonamides in the treatment of infections in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994690"}
{"pmid": "20994691", "title": "The psychological aspect of allergic skin reactions in childhood.", "content": "The psychological aspect of allergic skin reactions in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994691"}
{"pmid": "20994692", "title": "The statistics of prematurity; a plea for standardization.", "content": "The statistics of prematurity; a plea for standardization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994692"}
{"pmid": "20994694", "title": "The incidence of congenital pyloric stenosis.", "content": "The incidence of congenital pyloric stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994694"}
{"pmid": "20994693", "title": "Malnutrition in children under 3 years of age in Ashanti, West Africa.", "content": "Malnutrition in children under 3 years of age in Ashanti, West Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994693"}
{"pmid": "20994695", "title": "Dental fluorosis.", "content": "Dental fluorosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994695"}
{"pmid": "20994696", "title": "Pyocolpos in infancy.", "content": "Pyocolpos in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994696"}
{"pmid": "20994697", "title": "Mesenteric bands producing intestinal obstruction in a three-day old infant with recovery.", "content": "Mesenteric bands producing intestinal obstruction in a three-day old infant with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994697"}
{"pmid": "20994698", "title": "The child in school.", "content": "The child in school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994698"}
{"pmid": "20994699", "title": "Food poisoning as the etiological factor in poliomyelitis.", "content": "Food poisoning as the etiological factor in poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994699"}
{"pmid": "20994700", "title": "Diphtheria; myocarditis.", "content": "Diphtheria; myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994700"}
{"pmid": "20994701", "title": "Diphtheria; myocardial failure.", "content": "Diphtheria; myocardial failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994701"}
{"pmid": "20994702", "title": "Post-varicella myelitis.", "content": "Post-varicella myelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994702"}
{"pmid": "20994703", "title": "Measles and pneumonia treated with gamma globulin.", "content": "Measles and pneumonia treated with gamma globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994703"}
{"pmid": "20994704", "title": "Mumps; techniques of laboratory diagnosis, tests for susceptibility, and experiments on specific prophylaxis.", "content": "Mumps; techniques of laboratory diagnosis, tests for susceptibility, and experiments on specific prophylaxis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994704"}
{"pmid": "20994705", "title": "Juvenile rheumatoid arthritis; a study of fifty-six cases with a note on skeletal changes.", "content": "Juvenile rheumatoid arthritis; a study of fifty-six cases with a note on skeletal changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994705"}
{"pmid": "20994706", "title": "Epidemiologic studies in dental caries; the pattern of dental caries in Iowa City children.", "content": "Epidemiologic studies in dental caries; the pattern of dental caries in Iowa City children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994706"}
{"pmid": "20994707", "title": "The influence of human serum albumin on edema in erythroblastosis fetalis.", "content": "The influence of human serum albumin on edema in erythroblastosis fetalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994707"}
{"pmid": "20994708", "title": "Diagnosis and management of severe infections in infants and children; a review of experiences since the introduction of sulfonamide therapy; acute iliac lymphadenitis.", "content": "Diagnosis and management of severe infections in infants and children; a review of experiences since the introduction of sulfonamide therapy; acute iliac lymphadenitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994708"}
{"pmid": "20994709", "title": "The treatment of scabies in children with a new sarcopticide.", "content": "The treatment of scabies in children with a new sarcopticide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994709"}
{"pmid": "20994710", "title": "Streptomycin in pediatrics.", "content": "Streptomycin in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994710"}
{"pmid": "20994711", "title": "Salmonella anatum infection.", "content": "Salmonella anatum infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994711"}
{"pmid": "20994712", "title": "Treatment of epidemic diarrhea of the newborn.", "content": "Treatment of epidemic diarrhea of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994712"}
{"pmid": "20994713", "title": "Behavior aspects of the care of the premature infant.", "content": "Behavior aspects of the care of the premature infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994713"}
{"pmid": "20994714", "title": "Congenital adrenal cortical insufficiency associated with macrogenitosomia; follow-up and terminal report.", "content": "Congenital adrenal cortical insufficiency associated with macrogenitosomia; follow-up and terminal report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994714"}
{"pmid": "20994715", "title": "Congenital aortic atresia.", "content": "Congenital aortic atresia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994715"}
{"pmid": "20994716", "title": "Foreign body in duodenum causing urinary disturbance.", "content": "Foreign body in duodenum causing urinary disturbance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994716"}
{"pmid": "20994717", "title": "Malignancy of the genitourinary tract in children; report of a case of sarcoma of the vulva.", "content": "Malignancy of the genitourinary tract in children; report of a case of sarcoma of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994717"}
{"pmid": "20994718", "title": "A modification of the Brecht feeder.", "content": "A modification of the Brecht feeder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994718"}
{"pmid": "20994719", "title": "Cooperative national planning for improving child health services.", "content": "Cooperative national planning for improving child health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994719"}
{"pmid": "20994720", "title": "The action of sodium salicylate and sulfadiazine on hyaluronidase.", "content": "The action of sodium salicylate and sulfadiazine on hyaluronidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994720"}
{"pmid": "20994721", "title": "Digitalis; a chemical evaluation of tablets of digitoxin.", "content": "Digitalis; a chemical evaluation of tablets of digitoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994721"}
{"pmid": "20994722", "title": "Chemotherapy of Plasmodium knowlesi infections in Macaca mulatta monkeys.", "content": "Chemotherapy of Plasmodium knowlesi infections in Macaca mulatta monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994722"}
{"pmid": "20994723", "title": "Aggregation as a factor influencing the toxicity of sympathomimetic amines in mice.", "content": "Aggregation as a factor influencing the toxicity of sympathomimetic amines in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994723"}
{"pmid": "20994724", "title": "The action of tetraethylammonium ion on the mammalian circulation.", "content": "The action of tetraethylammonium ion on the mammalian circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994724"}
{"pmid": "20994725", "title": "Studies on the pharmacology of salicylates.", "content": "Studies on the pharmacology of salicylates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994725"}
{"pmid": "20994726", "title": "Pharmacodynamic studies of a new antihistamine agent, N'-pyridyl-N benzyl-N-dimethylethylene diamine HCI, pyribenzamine HCI; effects on salivation, nictitating membrane, lachrymation, pupil and blood pressure.", "content": "Pharmacodynamic studies of a new antihistamine agent, N'-pyridyl-N benzyl-N-dimethylethylene diamine HCI, pyribenzamine HCI; effects on salivation, nictitating membrane, lachrymation, pupil and blood pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994726"}
{"pmid": "20994727", "title": "Barbiturate antagonism of isonipecaine convulsions and isonipecaine potentiation of barbiturate depression.", "content": "Barbiturate antagonism of isonipecaine convulsions and isonipecaine potentiation of barbiturate depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994727"}
{"pmid": "20994728", "title": "The blocking effect of tetraethylammonium ion on the superior cervical ganglion of the cat.", "content": "The blocking effect of tetraethylammonium ion on the superior cervical ganglion of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994728"}
{"pmid": "20994729", "title": "The pharmacology of di-isopropyl fluorophosphate in man.", "content": "The pharmacology of di-isopropyl fluorophosphate in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994729"}
{"pmid": "20994730", "title": "Studies with tetrazole derivatives; some pharmacologic properties of aliphatic substituted pentamethylene tetrazole derivatives.", "content": "Studies with tetrazole derivatives; some pharmacologic properties of aliphatic substituted pentamethylene tetrazole derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994730"}
{"pmid": "20994731", "title": "Studies with tetrazole derivatives; some pharmacologic properties of 1,5-disubstituted tetrazoles.", "content": "Studies with tetrazole derivatives; some pharmacologic properties of 1,5-disubstituted tetrazoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994731"}
{"pmid": "20994732", "title": "The specificity of sex hormones on the tissue aldehyde shift in the rat kidney and of fuchsin sulfurous acid reagent on aldehydes.", "content": "The specificity of sex hormones on the tissue aldehyde shift in the rat kidney and of fuchsin sulfurous acid reagent on aldehydes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994732"}
{"pmid": "20994733", "title": "On the chemotherapeutic properties of the sulfanilanilides.", "content": "On the chemotherapeutic properties of the sulfanilanilides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994733"}
{"pmid": "20994740", "title": "Mental-health work in occupied Holland.", "content": "Mental-health work in occupied Holland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994740"}
{"pmid": "20994741", "title": "The mental-hygiene unit in a W. A. C. training center.", "content": "The mental-hygiene unit in a W. A. C. training center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994741"}
{"pmid": "20994742", "title": "Psychiatric plans of the United States Public Health Service.", "content": "Psychiatric plans of the United States Public Health Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994742"}
{"pmid": "20994743", "title": "Rehabilitation and mental handicaps.", "content": "Rehabilitation and mental handicaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994743"}
{"pmid": "20994744", "title": "Creative occupation as a basis for rehabilitation; a personal experience.", "content": "Creative occupation as a basis for rehabilitation; a personal experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994744"}
{"pmid": "20994745", "title": "The psychiatrist talks to foremen and counselors.", "content": "The psychiatrist talks to foremen and counselors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994745"}
{"pmid": "20994746", "title": "The growing problem of old-age psychoses; an analysis of the trend in one state hospital from 1910 to 1944.", "content": "The growing problem of old-age psychoses; an analysis of the trend in one state hospital from 1910 to 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994746"}
{"pmid": "20994747", "title": "Effects of 4F classification on psychoneurotics under treatment.", "content": "Effects of 4F classification on psychoneurotics under treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994747"}
{"pmid": "20994748", "title": "REVISED psychiatric nomenclature adopted by the Army.", "content": "REVISED psychiatric nomenclature adopted by the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994748"}
{"pmid": "20994749", "title": "The Manitoba health plan.", "content": "The Manitoba health plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994749"}
{"pmid": "20994750", "title": "Plague control with DDT and 1080; results achieved in a plague epidemic at Tumbes, Peru, 1945.", "content": "Plague control with DDT and 1080; results achieved in a plague epidemic at Tumbes, Peru, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994750"}
{"pmid": "20994751", "title": "Education of medical students in preventive medicine.", "content": "Education of medical students in preventive medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994751"}
{"pmid": "20994752", "title": "Training for health education.", "content": "Training for health education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994752"}
{"pmid": "20994753", "title": "Problems of recruitment and training.", "content": "Problems of recruitment and training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994753"}
{"pmid": "20994754", "title": "Accident prevention.", "content": "Accident prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994754"}
{"pmid": "20994755", "title": "Practical aspects of communicable disease control in the schools.", "content": "Practical aspects of communicable disease control in the schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994755"}
{"pmid": "20994756", "title": "Developments in the science of nutrition during World War II.", "content": "Developments in the science of nutrition during World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994756"}
{"pmid": "20994757", "title": "A study of the nutritional status and food habits of Otomi Indians in the Mezquital Valley of Mexico.", "content": "A study of the nutritional status and food habits of Otomi Indians in the Mezquital Valley of Mexico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994757"}
{"pmid": "20994758", "title": "Proposed report on the educational qualifications of health officers.", "content": "Proposed report on the educational qualifications of health officers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994758"}
{"pmid": "20994759", "title": "Medical care in Maryland.", "content": "Medical care in Maryland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994759"}
{"pmid": "20994761", "title": "PANIC or reason in dealing with poliomyelitis?", "content": "PANIC or reason in dealing with poliomyelitis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994761"}
{"pmid": "20994760", "title": "Health Insurance Plan of Greater New York.", "content": "Health Insurance Plan of Greater New York.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994760"}
{"pmid": "20994763", "title": "Eye clinics in the Arctic.", "content": "Eye clinics in the Arctic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994763"}
{"pmid": "20994762", "title": "GUNN-PLATT report.", "content": "GUNN-PLATT report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994762"}
{"pmid": "20994764", "title": "Canada's fight against tuberculosis.", "content": "Canada's fight against tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994764"}
{"pmid": "20994765", "title": "Surgical approach to hypertension.", "content": "Surgical approach to hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994765"}
{"pmid": "20994766", "title": "Fractures of the carpal scaphoid bone.", "content": "Fractures of the carpal scaphoid bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994766"}
{"pmid": "20994767", "title": "Pericoronary neurectomy in abolishing anginal pain in coronary disease.", "content": "Pericoronary neurectomy in abolishing anginal pain in coronary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994767"}
{"pmid": "20994768", "title": "Intraperitoneal administration of succinylsulfathiazole and phthalylsulfathiazole; their use in the prophylaxis and treatment of peritonitis.", "content": "Intraperitoneal administration of succinylsulfathiazole and phthalylsulfathiazole; their use in the prophylaxis and treatment of peritonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994768"}
{"pmid": "20994769", "title": "Lymphadenoid goiter; its differentiation from chronic thyroiditis.", "content": "Lymphadenoid goiter; its differentiation from chronic thyroiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994769"}
{"pmid": "20994771", "title": "Review of urologic surgery.", "content": "Review of urologic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994771"}
{"pmid": "20994770", "title": "Anaphylaxis-like reactions produced by ascaris extracts; the role played by leukocytes and platelets in the genesis of the shock.", "content": "Anaphylaxis-like reactions produced by ascaris extracts; the role played by leukocytes and platelets in the genesis of the shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994770"}
{"pmid": "20994772", "title": "A technique for segmental pulmonary resection with particular reference to lingulectomy.", "content": "A technique for segmental pulmonary resection with particular reference to lingulectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994772"}
{"pmid": "20994773", "title": "Pneumothorax therapy for early bronchiectasis.", "content": "Pneumothorax therapy for early bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994773"}
{"pmid": "20994774", "title": "Solitary primary neurogenic tumor of the lung.", "content": "Solitary primary neurogenic tumor of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994774"}
{"pmid": "20994775", "title": "Report of a clinical trial of oxidized gauze in seven thoracoplasties.", "content": "Report of a clinical trial of oxidized gauze in seven thoracoplasties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994775"}
{"pmid": "20994777", "title": "Mucocellular papillary adenocarcinoma of the lung and lobectomy.", "content": "Mucocellular papillary adenocarcinoma of the lung and lobectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994777"}
{"pmid": "20994776", "title": "Partial claviculectomy as an adjunct to surgical collapse of the chest wall.", "content": "Partial claviculectomy as an adjunct to surgical collapse of the chest wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994776"}
{"pmid": "20994778", "title": "Fate of the distal esophageal segment following the indirect surgical treatment of a congenital tracheoesophageal fistula.", "content": "Fate of the distal esophageal segment following the indirect surgical treatment of a congenital tracheoesophageal fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994778"}
{"pmid": "20994779", "title": "Intrathoracic goiter; report of a patient operated upon through the thorax.", "content": "Intrathoracic goiter; report of a patient operated upon through the thorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994779"}
{"pmid": "20994780", "title": "Esophagotracheal fistula due to nonpenetrating crushing injury.", "content": "Esophagotracheal fistula due to nonpenetrating crushing injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994780"}
{"pmid": "20994781", "title": "An accessory instrument tray.", "content": "An accessory instrument tray.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994781"}
{"pmid": "20994782", "title": "The development of plastic surgery in the United States.", "content": "The development of plastic surgery in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994782"}
{"pmid": "20994783", "title": "Present evaluation of the merits of the Z-plastic operation.", "content": "Present evaluation of the merits of the Z-plastic operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994783"}
{"pmid": "20994784", "title": "Release of circular constricting scar by Z flaps.", "content": "Release of circular constricting scar by Z flaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994784"}
{"pmid": "20994785", "title": "Reconstruction of the contracted axilla.", "content": "Reconstruction of the contracted axilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994785"}
{"pmid": "20994786", "title": "Early covering of extensive traumatic deformities of the hand and foot.", "content": "Early covering of extensive traumatic deformities of the hand and foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994786"}
{"pmid": "20994787", "title": "Loss of coverage of the penis, scrotum and urethra.", "content": "Loss of coverage of the penis, scrotum and urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994787"}
{"pmid": "20994788", "title": "The closure of skull defects.", "content": "The closure of skull defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994788"}
{"pmid": "20994789", "title": "Elongation of the nasal columella; a new operative technique.", "content": "Elongation of the nasal columella; a new operative technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994789"}
{"pmid": "20994790", "title": "Surgical treatment of ichthyosis hystrix.", "content": "Surgical treatment of ichthyosis hystrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994790"}
{"pmid": "20994791", "title": "Dermatape; a new method for the management of split skin grafts.", "content": "Dermatape; a new method for the management of split skin grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994791"}
{"pmid": "20994792", "title": "Permanent pigment injection of capillary hemangiomata.", "content": "Permanent pigment injection of capillary hemangiomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994792"}
{"pmid": "20994793", "title": "Experimental observations on the growth of young human cartilage grafts.", "content": "Experimental observations on the growth of young human cartilage grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994793"}
{"pmid": "20994794", "title": "Training in plastic surgery; visual aids.", "content": "Training in plastic surgery; visual aids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994794"}
{"pmid": "20994795", "title": "The surgeon; an individualist.", "content": "The surgeon; an individualist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994795"}
{"pmid": "20994796", "title": "Massive organizing hemothorax; operative treatment, its technique, indications, and pitfalls.", "content": "Massive organizing hemothorax; operative treatment, its technique, indications, and pitfalls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994796"}
{"pmid": "20994797", "title": "Further experiences in the surgical treatment of congenital atresia of the esophagus with tracheoesophageal fistula.", "content": "Further experiences in the surgical treatment of congenital atresia of the esophagus with tracheoesophageal fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994797"}
{"pmid": "20994798", "title": "Postoperative pulmonary embolism; a review of cases from 1939 to 1944.", "content": "Postoperative pulmonary embolism; a review of cases from 1939 to 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994798"}
{"pmid": "20994799", "title": "Management of pulmonary abscess.", "content": "Management of pulmonary abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994799"}
{"pmid": "20994800", "title": "Acute secondary parotitis.", "content": "Acute secondary parotitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994800"}
{"pmid": "20994801", "title": "Curare; its rational use as an adjunct to anesthesia.", "content": "Curare; its rational use as an adjunct to anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994801"}
{"pmid": "20994802", "title": "The role of cancellous bone in plastic surgery.", "content": "The role of cancellous bone in plastic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994802"}
{"pmid": "20994804", "title": "Tardy median palsy; median neuritis; median thenar neuritis amenable to surgery.", "content": "Tardy median palsy; median neuritis; median thenar neuritis amenable to surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994804"}
{"pmid": "20994803", "title": "A method in the management of multiple facial fractures.", "content": "A method in the management of multiple facial fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994803"}
{"pmid": "20994805", "title": "Fundamentals of technique in the transverse abdominal incision.", "content": "Fundamentals of technique in the transverse abdominal incision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994805"}
{"pmid": "20994806", "title": "Resection of the duodenum and head of the pancreas for carcinoma; an analysis of thirty cases.", "content": "Resection of the duodenum and head of the pancreas for carcinoma; an analysis of thirty cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994806"}
{"pmid": "20994807", "title": "Value of the exclusion operation in the treatment of intestinal fistulas.", "content": "Value of the exclusion operation in the treatment of intestinal fistulas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994807"}
{"pmid": "20994808", "title": "Reconstruction of war wounds of colon and rectum.", "content": "Reconstruction of war wounds of colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994808"}
{"pmid": "20994809", "title": "Transverse colostomy.", "content": "Transverse colostomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994809"}
{"pmid": "20994810", "title": "Radical perineal prostatectomy for carcinoma of prostate.", "content": "Radical perineal prostatectomy for carcinoma of prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994810"}
{"pmid": "20994811", "title": "Prostatic carcinoma; a follow-up on 795 patients treated prior to the endocrine era and a comparison of survival rates between these and patients treated by endocrine therapy.", "content": "Prostatic carcinoma; a follow-up on 795 patients treated prior to the endocrine era and a comparison of survival rates between these and patients treated by endocrine therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994811"}
{"pmid": "20994812", "title": "Malignant testicular neoplasms; analysis of 80 cases.", "content": "Malignant testicular neoplasms; analysis of 80 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994812"}
{"pmid": "20994813", "title": "Novocain infiltration in the treatment of acute ankle injuries without fracture.", "content": "Novocain infiltration in the treatment of acute ankle injuries without fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994813"}
{"pmid": "20994814", "title": "Metabolic alterations following thermal burns; the effect of altering the nitrogen and caloric intake or of administering testosterone propionate on the nitrogen balance.", "content": "Metabolic alterations following thermal burns; the effect of altering the nitrogen and caloric intake or of administering testosterone propionate on the nitrogen balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994814"}
{"pmid": "20994817", "title": "Physiotherapy in rheumatic diseases; the choice of suitable methods at various stages.", "content": "Physiotherapy in rheumatic diseases; the choice of suitable methods at various stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994817"}
{"pmid": "20994816", "title": "Physical methods in the treatment of so-called psychosomatic states.", "content": "Physical methods in the treatment of so-called psychosomatic states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994816"}
{"pmid": "20994815", "title": "Acute arthritis in adults.", "content": "Acute arthritis in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994815"}
{"pmid": "20994828", "title": "Age changes in the vascular architecture and cell content in the spleens of 100 Wistar In stitute rats, including comparisons with human material.", "content": "Age changes in the vascular architecture and cell content in the spleens of 100 Wistar In stitute rats, including comparisons with human material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994828"}
{"pmid": "20994829", "title": "Cellular gigantism and pluripolar mitosis in human hematopoiesis.", "content": "Cellular gigantism and pluripolar mitosis in human hematopoiesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994829"}
{"pmid": "20994818", "title": "Medical certificates for women in industry.", "content": "Medical certificates for women in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994818"}
{"pmid": "20994830", "title": "A morphological and histochemical study of the rat's adrenal cortex after hypoph ysectomy, with comments on the liver.", "content": "A morphological and histochemical study of the rat's adrenal cortex after hypoph ysectomy, with comments on the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994830"}
{"pmid": "20994820", "title": "Fluorescence and ultraviolet radiation.", "content": "Fluorescence and ultraviolet radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994820"}
{"pmid": "20994819", "title": "The evaluation of actinotherapy.", "content": "The evaluation of actinotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994819"}
{"pmid": "20994831", "title": "The position and mobility of the duodenum in the living subject.", "content": "The position and mobility of the duodenum in the living subject.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994831"}
{"pmid": "20994823", "title": "The use of the sigmoidoscope in the diagnosis and prognosis of amoebic dysentery.", "content": "The use of the sigmoidoscope in the diagnosis and prognosis of amoebic dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994823"}
{"pmid": "20994824", "title": "The cephalin-cholesterol flocculation test in typhoid and typhus fevers.", "content": "The cephalin-cholesterol flocculation test in typhoid and typhus fevers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994824"}
{"pmid": "20994832", "title": "Situs inversus viscerum in conjoined twins of the brook trout.", "content": "Situs inversus viscerum in conjoined twins of the brook trout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994832"}
{"pmid": "20994833", "title": "Structure, motility and locomotion in isolated embryonic amphibian cells.", "content": "Structure, motility and locomotion in isolated embryonic amphibian cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994833"}
{"pmid": "20994834", "title": "Histology of gonadal changes in the bluegill, Lepomis macrochirus Rafinesque, and the largemouth bass, Huro salmoides (Lacépède).", "content": "Histology of gonadal changes in the bluegill, Lepomis macrochirus Rafinesque, and the largemouth bass, Huro salmoides (Lacépède).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994834"}
{"pmid": "20994821", "title": "Constipation and local ultra-violet irradiation.", "content": "Constipation and local ultra-violet irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994821"}
{"pmid": "20994836", "title": "Cytological studies on Acrididae; the structure of the x-chromosome in the meiosis of Phlaeoba infumata.", "content": "Cytological studies on Acrididae; the structure of the x-chromosome in the meiosis of Phlaeoba infumata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994836"}
{"pmid": "20994835", "title": "The gustatory papillae and the stomach of Hyracoidea, with a discussion of the evolution of the mammalian tongue papillae.", "content": "The gustatory papillae and the stomach of Hyracoidea, with a discussion of the evolution of the mammalian tongue papillae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994835"}
{"pmid": "20994822", "title": "The non-specific chemotherapy of malaria.", "content": "The non-specific chemotherapy of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994822"}
{"pmid": "20994826", "title": "Penicillin in Chaga's disease; with a note on Chaga's disease in Ecuador.", "content": "Penicillin in Chaga's disease; with a note on Chaga's disease in Ecuador.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994826"}
{"pmid": "20994837", "title": "Hermaphroditism in the largemouth bass.", "content": "Hermaphroditism in the largemouth bass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994837"}
{"pmid": "20994838", "title": "An analysis of 500 obstetrical cases with continuous caudal anesthesia using pontocaine.", "content": "An analysis of 500 obstetrical cases with continuous caudal anesthesia using pontocaine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994838"}
{"pmid": "20994839", "title": "A clinical study of carbon dioxide absorption during anesthesia.", "content": "A clinical study of carbon dioxide absorption during anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994839"}
{"pmid": "20994825", "title": "A case of snake-bite.", "content": "A case of snake-bite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994825"}
{"pmid": "20994840", "title": "Alveolar and arterial oxygen contents during oropharyngeal oxygen therapy.", "content": "Alveolar and arterial oxygen contents during oropharyngeal oxygen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994840"}
{"pmid": "20994842", "title": "Edema of the larynx, a rare complication of endotracheal anesthesia.", "content": "Edema of the larynx, a rare complication of endotracheal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994842"}
{"pmid": "20994841", "title": "Observations on the carbohydrate metabolism during prolonged pentothal anesthesia in dogs; the blood sugar and the liver glycogen.", "content": "Observations on the carbohydrate metabolism during prolonged pentothal anesthesia in dogs; the blood sugar and the liver glycogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994841"}
{"pmid": "20994827", "title": "Tropical pyomyositis and its relation to deficiency of the vitamin-B complex.", "content": "Tropical pyomyositis and its relation to deficiency of the vitamin-B complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994827"}
{"pmid": "20994843", "title": "Unusual incidents following spinal anesthesia.", "content": "Unusual incidents following spinal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994843"}
{"pmid": "20994844", "title": "Acute aseptic meningitis following paravertebral lumbar sympathetic blocks.", "content": "Acute aseptic meningitis following paravertebral lumbar sympathetic blocks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994844"}
{"pmid": "20994845", "title": "Nitrous oxide-cyclopropanecurare anesthesia.", "content": "Nitrous oxide-cyclopropanecurare anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994845"}
{"pmid": "20994846", "title": "An aid in placing endotracheal tubes a measured distance below the vocal cords.", "content": "An aid in placing endotracheal tubes a measured distance below the vocal cords.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994846"}
{"pmid": "20994847", "title": "Management of the airway in compression of the lower end of the trachea.", "content": "Management of the airway in compression of the lower end of the trachea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994847"}
{"pmid": "20994848", "title": "A modified catheter for oropharyngeal, nasopharyngeal and tracheobronchial aspiration, with a further modification for enterostomy drainage.", "content": "A modified catheter for oropharyngeal, nasopharyngeal and tracheobronchial aspiration, with a further modification for enterostomy drainage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994848"}
{"pmid": "20994849", "title": "Electrocardiograms of older pilots.", "content": "Electrocardiograms of older pilots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994849"}
{"pmid": "20994850", "title": "Fatal aviation accidents.", "content": "Fatal aviation accidents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994850"}
{"pmid": "20994851", "title": "Analysis of symptoms causing forced descents in the altitude chambers at the San Antonio Aviation Cadet Center.", "content": "Analysis of symptoms causing forced descents in the altitude chambers at the San Antonio Aviation Cadet Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994851"}
{"pmid": "20994852", "title": "Physical fatigue in single control military aircraft.", "content": "Physical fatigue in single control military aircraft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994852"}
{"pmid": "20994853", "title": "The incidence and relation of syncope to decompression sickness.", "content": "The incidence and relation of syncope to decompression sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994853"}
{"pmid": "20994854", "title": "Studies of the effects of morphine at simulated high altitudes and its use for the relief of pain of decompression sickness.", "content": "Studies of the effects of morphine at simulated high altitudes and its use for the relief of pain of decompression sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994854"}
{"pmid": "20994855", "title": "Psychological requirements in aviation equipment design.", "content": "Psychological requirements in aviation equipment design.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994855"}
{"pmid": "20994856", "title": "INSECTICIDES and disinfectants.", "content": "INSECTICIDES and disinfectants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994856"}
{"pmid": "20994857", "title": "Chemical evaluation of technical DDT by dehydrochlorination.", "content": "Chemical evaluation of technical DDT by dehydrochlorination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994857"}
{"pmid": "20994858", "title": "PEET-Grady method [insecticide testing].", "content": "PEET-Grady method [insecticide testing].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994858"}
{"pmid": "20994859", "title": "Use of Francis' glucose cystine blood agar in the isolation and cultivation of Sporotrichum schenckii.", "content": "Use of Francis' glucose cystine blood agar in the isolation and cultivation of Sporotrichum schenckii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994859"}
{"pmid": "20994860", "title": "The value of concentrated human whole blood and agar cultures for testing the coagulating power of staphylococci.", "content": "The value of concentrated human whole blood and agar cultures for testing the coagulating power of staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994860"}
{"pmid": "20994862", "title": "The influence of inorganic salts on penicillin production.", "content": "The influence of inorganic salts on penicillin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994862"}
{"pmid": "20994861", "title": "Problems in the estimation of niacin and riboflavin by microbiological methods.", "content": "Problems in the estimation of niacin and riboflavin by microbiological methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994861"}
{"pmid": "20994863", "title": "Experimental carditis.", "content": "Experimental carditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994863"}
{"pmid": "20994864", "title": "Botulinum toxin (type A); including a study of shaking with chloroform as a step in the isolation procedure.", "content": "Botulinum toxin (type A); including a study of shaking with chloroform as a step in the isolation procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994864"}
{"pmid": "20994865", "title": "The taxonomic position of Corynebacterium acnes.", "content": "The taxonomic position of Corynebacterium acnes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994865"}
{"pmid": "20994866", "title": "The separation of different strains of bacteriophage from a crude culture.", "content": "The separation of different strains of bacteriophage from a crude culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994866"}
{"pmid": "20994867", "title": "In vitro studies concerning the action of penicillin on the viridans streptococci, including observations on the so-called synergistic effect of sulfonamide drugs.", "content": "In vitro studies concerning the action of penicillin on the viridans streptococci, including observations on the so-called synergistic effect of sulfonamide drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994867"}
{"pmid": "20994868", "title": "Strain variation as a factor in the sporulating properties of the so-called Bacillus globigii.", "content": "Strain variation as a factor in the sporulating properties of the so-called Bacillus globigii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994868"}
{"pmid": "20994869", "title": "Sampling devices for air-borne bacteria.", "content": "Sampling devices for air-borne bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994869"}
{"pmid": "20994870", "title": "The effect of streptomycin on Proteus infections of the chick embryo.", "content": "The effect of streptomycin on Proteus infections of the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994870"}
{"pmid": "20994872", "title": "The relative activity of penicillins F, G, K, and X against spirochetes and streptococci in vitro.", "content": "The relative activity of penicillins F, G, K, and X against spirochetes and streptococci in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994872"}
{"pmid": "20994871", "title": "Studies on the death of bacteria at low temperatures; the comparative effects of crystallization, vitromelting, and devitrification on the mortality of Esche richia coli.", "content": "Studies on the death of bacteria at low temperatures; the comparative effects of crystallization, vitromelting, and devitrification on the mortality of Esche richia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994871"}
{"pmid": "20994873", "title": "The activity of penicillin in relation to bacterial spores and the preservation of milk.", "content": "The activity of penicillin in relation to bacterial spores and the preservation of milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994873"}
{"pmid": "20994874", "title": "The nature of the acid-fast stain.", "content": "The nature of the acid-fast stain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994874"}
{"pmid": "20994875", "title": "The influence of folic acid deficiency in Macaca mulatta on susceptibility to experimental poliomyelitis.", "content": "The influence of folic acid deficiency in Macaca mulatta on susceptibility to experimental poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994875"}
{"pmid": "20994876", "title": "Cetyl pyridinium chloride; germicidal properties.", "content": "Cetyl pyridinium chloride; germicidal properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994876"}
{"pmid": "20994877", "title": "The effect of environmental conditions on penicillin fermentations with Penicillium chrysogenum X-1612.", "content": "The effect of environmental conditions on penicillin fermentations with Penicillium chrysogenum X-1612.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994877"}
{"pmid": "20994878", "title": "A comparison of penicillin-producing strains of Penicillium notatum-chrysogenum.", "content": "A comparison of penicillin-producing strains of Penicillium notatum-chrysogenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994878"}
{"pmid": "20994879", "title": "The preparation of Loeffler's serum and similar coagulable mediums.", "content": "The preparation of Loeffler's serum and similar coagulable mediums.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994879"}
{"pmid": "20994880", "title": "The activity of streptomycin in relation to bacterial spores and the preservation of milk.", "content": "The activity of streptomycin in relation to bacterial spores and the preservation of milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994880"}
{"pmid": "20994881", "title": "Hydrogen sulfide formation by Shigella alkalescens.", "content": "Hydrogen sulfide formation by Shigella alkalescens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994881"}
{"pmid": "20994882", "title": "Trimethylamine oxide reduction and the Eijkman reaction in the genus Erwinia.", "content": "Trimethylamine oxide reduction and the Eijkman reaction in the genus Erwinia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994882"}
{"pmid": "20994884", "title": "The occurrence of Salmonella blegdam in the Philippines.", "content": "The occurrence of Salmonella blegdam in the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994884"}
{"pmid": "20994883", "title": "The antibiotic activity of violacein, prodigiosin, and phth iocol.", "content": "The antibiotic activity of violacein, prodigiosin, and phth iocol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994883"}
{"pmid": "20994885", "title": "A note of Salmonella abortus-equi infection in man.", "content": "A note of Salmonella abortus-equi infection in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994885"}
{"pmid": "20994887", "title": "Trial of volatile compounds as removable antiseptics.", "content": "Trial of volatile compounds as removable antiseptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994887"}
{"pmid": "20994886", "title": "Agglutinin responses to the 0 and 0H antigen of typhoid vaccine administered orally to rabbits.", "content": "Agglutinin responses to the 0 and 0H antigen of typhoid vaccine administered orally to rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994886"}
{"pmid": "20994888", "title": "The incidence of staphylococcal mastitis in the Northwest.", "content": "The incidence of staphylococcal mastitis in the Northwest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994888"}
{"pmid": "20994889", "title": "Siderocytes in mammalian blood.", "content": "Siderocytes in mammalian blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994889"}
{"pmid": "20994890", "title": "The reproduction of the house-mouse (Mus musculus) living in different environments.", "content": "The reproduction of the house-mouse (Mus musculus) living in different environments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994890"}
{"pmid": "20994891", "title": "Filtration of droplets in the nose of the rabbit.", "content": "Filtration of droplets in the nose of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994891"}
{"pmid": "20994892", "title": "The differential effect of synthetic plant growth substances and other compounds upon plant species; seed germination and early growth responses to alpha-naphthylacetic acid and compounds of the general formula aryl OCH2COOR.", "content": "The differential effect of synthetic plant growth substances and other compounds upon plant species; seed germination and early growth responses to alpha-naphthylacetic acid and compounds of the general formula aryl OCH2COOR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994892"}
{"pmid": "20994893", "title": "Control of nucleic acid charge on the x-chromosome of the hamster.", "content": "Control of nucleic acid charge on the x-chromosome of the hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994893"}
{"pmid": "20994894", "title": "A study of an insect cuticle; the larval cuticle of Sarcophaga falculata Pand. (Diptera).", "content": "A study of an insect cuticle; the larval cuticle of Sarcophaga falculata Pand. (Diptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994894"}
{"pmid": "20994895", "title": "Excitation of the nerve-muscle system in Crustacea.", "content": "Excitation of the nerve-muscle system in Crustacea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994895"}
{"pmid": "20994896", "title": "Sympatheticotonus and rheumatism.", "content": "Sympatheticotonus and rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994896"}
{"pmid": "20994897", "title": "Focal infection.", "content": "Focal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994897"}
{"pmid": "20994898", "title": "Prognosis of spondylitis in relation to treatment.", "content": "Prognosis of spondylitis in relation to treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994898"}
{"pmid": "20994909", "title": "The precordial electrocardiogram in high lateral myocardial infarction.", "content": "The precordial electrocardiogram in high lateral myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994909"}
{"pmid": "20994900", "title": "Sub-éltoid bursitis and a few other conditions causing pain in the shoulder.", "content": "Sub-éltoid bursitis and a few other conditions causing pain in the shoulder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994900"}
{"pmid": "20994910", "title": "The demonstration of ventricular septal defect by means of right heart catheterization.", "content": "The demonstration of ventricular septal defect by means of right heart catheterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994910"}
{"pmid": "20994911", "title": "A simplified and more standardized technique for recording multiple precordial electrocardiograms.", "content": "A simplified and more standardized technique for recording multiple precordial electrocardiograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994911"}
{"pmid": "20994899", "title": "Rheumatism in the Navy.", "content": "Rheumatism in the Navy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994899"}
{"pmid": "20994912", "title": "Influence of variations in atmospheric temperature and humidity on the rates of water and heat loss from the respiratory tract of patients with congestive heart failure living in a subtropical climate.", "content": "Influence of variations in atmospheric temperature and humidity on the rates of water and heat loss from the respiratory tract of patients with congestive heart failure living in a subtropical climate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994912"}
{"pmid": "20994901", "title": "Pre-rheumatoid.", "content": "Pre-rheumatoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994901"}
{"pmid": "20994903", "title": "Thorium X in spondylitis and chronic rheumatism.", "content": "Thorium X in spondylitis and chronic rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994903"}
{"pmid": "20994913", "title": "The effect of meals on the electrocardiogram in normal subjects.", "content": "The effect of meals on the electrocardiogram in normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994913"}
{"pmid": "20994902", "title": "Notes on the management of the rheumatic patient.", "content": "Notes on the management of the rheumatic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994902"}
{"pmid": "20994906", "title": "Some methods of treatment of rheumatism in the U.S.A.", "content": "Some methods of treatment of rheumatism in the U.S.A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994906"}
{"pmid": "20994914", "title": "The velocity of blood flow in normal pregnant women.", "content": "The velocity of blood flow in normal pregnant women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994914"}
{"pmid": "20994905", "title": "Infection of the cervix uteri and rheumatism.", "content": "Infection of the cervix uteri and rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994905"}
{"pmid": "20994915", "title": "Acute pericarditis in young adults.", "content": "Acute pericarditis in young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994915"}
{"pmid": "20994916", "title": "The incidence of rheumatic fever and heart disease in school children in Dublin, Georgia, with some epidemiological and sociological observations.", "content": "The incidence of rheumatic fever and heart disease in school children in Dublin, Georgia, with some epidemiological and sociological observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994916"}
{"pmid": "20994904", "title": "Focal sepsis; rhinological point of view.", "content": "Focal sepsis; rhinological point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994904"}
{"pmid": "20994917", "title": "Anomalous origin of the left coronary artery from the pulmonary artery; report of a case diagnosed clinically and confirmed by necropsy.", "content": "Anomalous origin of the left coronary artery from the pulmonary artery; report of a case diagnosed clinically and confirmed by necropsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994917"}
{"pmid": "20994918", "title": "Combined sulfonamide and diphtheritic myocarditis in cutaneous diphtheria.", "content": "Combined sulfonamide and diphtheritic myocarditis in cutaneous diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994918"}
{"pmid": "20994907", "title": "Chronic oral sepsis and its relation to rheumatism.", "content": "Chronic oral sepsis and its relation to rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994907"}
{"pmid": "20994919", "title": "Paroxysmal ventricular tachycardia followed by electrocardiographic syndrome.", "content": "Paroxysmal ventricular tachycardia followed by electrocardiographic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994919"}
{"pmid": "20994922", "title": "Studies in penicillin production by Penicillium notatum, in surface culture; a preliminary study of the metabolism of carbon, nitrogen, sulphur and phosphorus.", "content": "Studies in penicillin production by Penicillium notatum, in surface culture; a preliminary study of the metabolism of carbon, nitrogen, sulphur and phosphorus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994922"}
{"pmid": "20994924", "title": "A method for the determination of fat in faeces.", "content": "A method for the determination of fat in faeces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994924"}
{"pmid": "20994908", "title": "To move or not to move.", "content": "To move or not to move.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994908"}
{"pmid": "20994927", "title": "The influence of biotin upon the relative lipotropic effects of choline and inositol.", "content": "The influence of biotin upon the relative lipotropic effects of choline and inositol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994927"}
{"pmid": "20994937", "title": "The tryptophanase-tryptophan reaction; further evidence regarding the mechanism of the enzymic degradation of tryptophan to indole; criticism of the theory that beta-o-aminophenylacetaldehyde is the indole-forming intermediate.", "content": "The tryptophanase-tryptophan reaction; further evidence regarding the mechanism of the enzymic degradation of tryptophan to indole; criticism of the theory that beta-o-aminophenylacetaldehyde is the indole-forming intermediate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994937"}
{"pmid": "20994939", "title": "The sedimentation constant of insulin.", "content": "The sedimentation constant of insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994939"}
{"pmid": "20994940", "title": "The metabolism of aromatic amines.", "content": "The metabolism of aromatic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994940"}
{"pmid": "20994941", "title": "The formation of nicotinamide from nicotinic acid by rat tissues.", "content": "The formation of nicotinamide from nicotinic acid by rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994941"}
{"pmid": "20994942", "title": "The influence of changes in diet and of drugs on the urinary elimination of nicotinamide methochloride by rats.", "content": "The influence of changes in diet and of drugs on the urinary elimination of nicotinamide methochloride by rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994942"}
{"pmid": "20994943", "title": "Penicillin production of fractions from the pea (Pisum sativum).", "content": "Penicillin production of fractions from the pea (Pisum sativum).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994943"}
{"pmid": "20994944", "title": "HCl secretion in the isolated gastric mucosa.", "content": "HCl secretion in the isolated gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994944"}
{"pmid": "20994945", "title": "Relations between HCl secretion and electrical phenomena in frog gastric mucosa.", "content": "Relations between HCl secretion and electrical phenomena in frog gastric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994945"}
{"pmid": "20994946", "title": "The menstrual cycle and creatine-creatinine excretion.", "content": "The menstrual cycle and creatine-creatinine excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994946"}
{"pmid": "20994947", "title": "Creatinine formation in the isolated rabbit kidney.", "content": "Creatinine formation in the isolated rabbit kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994947"}
{"pmid": "20994948", "title": "Studies in the quinoline series; quinolyl mercaptans and sulfides.", "content": "Studies in the quinoline series; quinolyl mercaptans and sulfides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994948"}
{"pmid": "20994949", "title": "Arsenicals in the isoquinoline series.", "content": "Arsenicals in the isoquinoline series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994949"}
{"pmid": "20994950", "title": "4-Amino-4'-hydroxylaminodiphenyl sulfone, its acetyl and D-glucosyl derivatives.", "content": "4-Amino-4'-hydroxylaminodiphenyl sulfone, its acetyl and D-glucosyl derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994950"}
{"pmid": "20994951", "title": "Sugar interconversion under reducing conditions.", "content": "Sugar interconversion under reducing conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994951"}
{"pmid": "20994952", "title": "Chromatography of sugars and related polyhydroxy compounds.", "content": "Chromatography of sugars and related polyhydroxy compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994952"}
{"pmid": "20994953", "title": "d-Gluco-l-tagato-octose.", "content": "d-Gluco-l-tagato-octose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994953"}
{"pmid": "20994954", "title": "A new aldehyde synthesis.", "content": "A new aldehyde synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994954"}
{"pmid": "20994955", "title": "Streptomyces antibiotics; isolation of streptomycin.", "content": "Streptomyces antibiotics; isolation of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994955"}
{"pmid": "20994956", "title": "Resolution of racemic alpha-hydroxy-beta, beta-dimethyl-gamma-butyrolactone.", "content": "Resolution of racemic alpha-hydroxy-beta, beta-dimethyl-gamma-butyrolactone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994956"}
{"pmid": "20994957", "title": "Isolation and structure of an enzymatically synthesized crystalline disaccharide d-glucosido-d-ketoxyloside.", "content": "Isolation and structure of an enzymatically synthesized crystalline disaccharide d-glucosido-d-ketoxyloside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994957"}
{"pmid": "20994958", "title": "The preparation and properties of some beta-aminopropionic acid derivatives.", "content": "The preparation and properties of some beta-aminopropionic acid derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994958"}
{"pmid": "20994959", "title": "Esterification of galacturonic acid and polyuronides with methanol-hydrogen chloride.", "content": "Esterification of galacturonic acid and polyuronides with methanol-hydrogen chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994959"}
{"pmid": "20994960", "title": "The rate of oxidation of thiodiglycol and triethylamine by hydrogen peroxide.", "content": "The rate of oxidation of thiodiglycol and triethylamine by hydrogen peroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994960"}
{"pmid": "20994961", "title": "The binding of organic ions by proteins.", "content": "The binding of organic ions by proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994961"}
{"pmid": "20994962", "title": "Studies of sulfonates; some surface and interfacial tension measurements with aqueous solutions of certain alkanesulfonates.", "content": "Studies of sulfonates; some surface and interfacial tension measurements with aqueous solutions of certain alkanesulfonates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994962"}
{"pmid": "20994963", "title": "Hydroxylation and epoxidation of some l-olefins with per-acids.", "content": "Hydroxylation and epoxidation of some l-olefins with per-acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994963"}
{"pmid": "20994964", "title": "alpha-Isopropyl-5-methyl-2-oxo-4-imidazolidinepropionic acid, a structural isomer of desthiobiotin.", "content": "alpha-Isopropyl-5-methyl-2-oxo-4-imidazolidinepropionic acid, a structural isomer of desthiobiotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994964"}
{"pmid": "20994965", "title": "A study of plasmochin and the occurrence of rearrangements in the preparation of certain plasmo chin analogs.", "content": "A study of plasmochin and the occurrence of rearrangements in the preparation of certain plasmo chin analogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994965"}
{"pmid": "20994966", "title": "Alkylaminoalkyl derivatives of 8-aminoquinoline.", "content": "Alkylaminoalkyl derivatives of 8-aminoquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994966"}
{"pmid": "20994967", "title": "Synthetic antimalarials; 8-(5-isopropylaminoamylamino)-6-methoxyquinoline (SW-13,276) and some related compounds.", "content": "Synthetic antimalarials; 8-(5-isopropylaminoamylamino)-6-methoxyquinoline (SW-13,276) and some related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994967"}
{"pmid": "20994968", "title": "The synthesis of some 8-aminoquinolines.", "content": "The synthesis of some 8-aminoquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994968"}
{"pmid": "20994969", "title": "Synthetic antimalarials; some derivatives of 8-aminoquinoline.", "content": "Synthetic antimalarials; some derivatives of 8-aminoquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994969"}
{"pmid": "20994971", "title": "Some derivatives of 8-aminoquinoline.", "content": "Some derivatives of 8-aminoquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994971"}
{"pmid": "20994970", "title": "Synthesis of antimalarials; synthesis of certain 8-aminoquinolines.", "content": "Synthesis of antimalarials; synthesis of certain 8-aminoquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994970"}
{"pmid": "20994972", "title": "Synthesis of 6-phenoxy-8-(3'diethylaminopropylamino)-quinoline.", "content": "Synthesis of 6-phenoxy-8-(3'diethylaminopropylamino)-quinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994972"}
{"pmid": "20994973", "title": "Synthesis of 8-(3'diethylaminopropylamino)-6-methoxy-5-phenyl-quinoline.", "content": "Synthesis of 8-(3'diethylaminopropylamino)-6-methoxy-5-phenyl-quinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994973"}
{"pmid": "20994974", "title": "5-Methyl-6-methoxy-8-(2'-diethylaminoethylamino)-quinoline.", "content": "5-Methyl-6-methoxy-8-(2'-diethylaminoethylamino)-quinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994974"}
{"pmid": "20994976", "title": "The synthesis of potential antimalarials; some 2-substituted 8-(3-diethylaminopropylamino)-quinolines.", "content": "The synthesis of potential antimalarials; some 2-substituted 8-(3-diethylaminopropylamino)-quinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994976"}
{"pmid": "20994975", "title": "8-(3-Diethylamino-2-hydroxypropylamino)-5,6-dimethyoxyquinoline and some of its homologs.", "content": "8-(3-Diethylamino-2-hydroxypropylamino)-5,6-dimethyoxyquinoline and some of its homologs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994975"}
{"pmid": "20994977", "title": "Studies in the quinoline series; the preparation of some 8-(omega-alkylaminoalkylamino)-quinolines.", "content": "Studies in the quinoline series; the preparation of some 8-(omega-alkylaminoalkylamino)-quinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994977"}
{"pmid": "20994978", "title": "Studies in the quinoline series; the preparation of some 5-amino-8-(omega-dialkylaminoalkylamino)-quinolines.", "content": "Studies in the quinoline series; the preparation of some 5-amino-8-(omega-dialkylaminoalkylamino)-quinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994978"}
{"pmid": "20994979", "title": "Some N-substituted aminoquinolines.", "content": "Some N-substituted aminoquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994979"}
{"pmid": "20994980", "title": "8-[3-(3'-Aminopropylamino)-propylamino]-6-methoxyquinoline.", "content": "8-[3-(3'-Aminopropylamino)-propylamino]-6-methoxyquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994980"}
{"pmid": "20994981", "title": "Heterocyclic basic compounds; 8-[3-(3'-aminopropylamino)-propylamino]-6-methoxyquinoline.", "content": "Heterocyclic basic compounds; 8-[3-(3'-aminopropylamino)-propylamino]-6-methoxyquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994981"}
{"pmid": "20994982", "title": "Aminoalkylamino derivatives of 8-aminoquinoline.", "content": "Aminoalkylamino derivatives of 8-aminoquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994982"}
{"pmid": "20994983", "title": "Studies in the quinoline series; some 6-beta-hydroxyethoxy-8-(Omega-monoalkylaminoalkylamino)-quinolines.", "content": "Studies in the quinoline series; some 6-beta-hydroxyethoxy-8-(Omega-monoalkylaminoalkylamino)-quinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994983"}
{"pmid": "20994984", "title": "The synthesis of some substituted 8-aminoquinolines.", "content": "The synthesis of some substituted 8-aminoquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994984"}
{"pmid": "20994985", "title": "A sulfur analog of the plasmochin type: 8-(-diethylaminopropylamino)-6-quinolyl methyl sulfide.", "content": "A sulfur analog of the plasmochin type: 8-(-diethylaminopropylamino)-6-quinolyl methyl sulfide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994985"}
{"pmid": "20994986", "title": "Synthesis of l-alkylamino-4-bromopentane derivatives and of other amino halides.", "content": "Synthesis of l-alkylamino-4-bromopentane derivatives and of other amino halides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994986"}
{"pmid": "20994987", "title": "Synthesis of 5-substituted derivatives of 6-methoxy-8-aminoquinoline and of 5-chloro-6-methoxyquinoline.", "content": "Synthesis of 5-substituted derivatives of 6-methoxy-8-aminoquinoline and of 5-chloro-6-methoxyquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994987"}
{"pmid": "20994988", "title": "Syntheses of certain 8-nitroquinolines.", "content": "Syntheses of certain 8-nitroquinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994988"}
{"pmid": "20994989", "title": "Synthesis of simple 2-phenyl-8-aminoquinoline derivatives.", "content": "Synthesis of simple 2-phenyl-8-aminoquinoline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994989"}
{"pmid": "20994990", "title": "5- and 7-Chloro-8-aminoquinoline.", "content": "5- and 7-Chloro-8-aminoquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994990"}
{"pmid": "20994991", "title": "4-(6-Diethylaminohexylamino)-6-methoxy-benzothiazole (SN 15, 295).", "content": "4-(6-Diethylaminohexylamino)-6-methoxy-benzothiazole (SN 15, 295).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994991"}
{"pmid": "20994992", "title": "The Bucherer reaction on 5-hydroxybenzo (f) quinoline.", "content": "The Bucherer reaction on 5-hydroxybenzo (f) quinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994992"}
{"pmid": "20994993", "title": "Heterocyclic basic compounds; 3,6-dichloro-9-(1-methyl-4-diethylaminobuty)-aminoacridine.", "content": "Heterocyclic basic compounds; 3,6-dichloro-9-(1-methyl-4-diethylaminobuty)-aminoacridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994993"}
{"pmid": "20994994", "title": "Synthesis of substituted aminobenzacridines.", "content": "Synthesis of substituted aminobenzacridines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994994"}
{"pmid": "20994995", "title": "Synthetic antimalarials; the preparation of certain derivatives of sulfanilamide.", "content": "Synthetic antimalarials; the preparation of certain derivatives of sulfanilamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994995"}
{"pmid": "20994996", "title": "beta-Dimethylaminoethylamine and dimethylaminoacetonitrile.", "content": "beta-Dimethylaminoethylamine and dimethylaminoacetonitrile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994996"}
{"pmid": "20994997", "title": "Tropanone and its homologs.", "content": "Tropanone and its homologs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994997"}
{"pmid": "20994998", "title": "The preparation of DDT using hydrogen fluoride as the condensing agent.", "content": "The preparation of DDT using hydrogen fluoride as the condensing agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994998"}
{"pmid": "20994999", "title": "Studies in organic peroxides; molecular refractivity and the structure of organic peroxides.", "content": "Studies in organic peroxides; molecular refractivity and the structure of organic peroxides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20994999"}
{"pmid": "20995000", "title": "Periodate oxidation of certain active methylene groups.", "content": "Periodate oxidation of certain active methylene groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995000"}
{"pmid": "20995002", "title": "The heat of vaporization as a function of pressure and temperature.", "content": "The heat of vaporization as a function of pressure and temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995002"}
{"pmid": "20995001", "title": "Shape and size of pectinic acid molecules deduced from viscometric measurements.", "content": "Shape and size of pectinic acid molecules deduced from viscometric measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995001"}
{"pmid": "20995003", "title": "The effects of radioactivity on fatty acids.", "content": "The effects of radioactivity on fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995003"}
{"pmid": "20995004", "title": "Preparation of dihydropyran delta-hydroxyvaleraldehyde and 1,5-pentanediol from tetrahydrofurfuryl alcohol.", "content": "Preparation of dihydropyran delta-hydroxyvaleraldehyde and 1,5-pentanediol from tetrahydrofurfuryl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995004"}
{"pmid": "20995005", "title": "N-alkamine substituted phthalimides.", "content": "N-alkamine substituted phthalimides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995005"}
{"pmid": "20995006", "title": "The resistance to hydrogenation of beta-stenols in ethyl acetate with Adams platinum oxide catalyst.", "content": "The resistance to hydrogenation of beta-stenols in ethyl acetate with Adams platinum oxide catalyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995006"}
{"pmid": "20995008", "title": "Crystalline racemic calcium pantothenate.", "content": "Crystalline racemic calcium pantothenate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995008"}
{"pmid": "20995007", "title": "Specificity of the action of urease.", "content": "Specificity of the action of urease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995007"}
{"pmid": "20995009", "title": "Effect of phenylacetic acid derivatives on the types of penicillin produced by Penicillum chrysogenum Q176.", "content": "Effect of phenylacetic acid derivatives on the types of penicillin produced by Penicillum chrysogenum Q176.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995009"}
{"pmid": "20995010", "title": "The molecular size and shape of botulinus toxin.", "content": "The molecular size and shape of botulinus toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995010"}
{"pmid": "20995011", "title": "The toxicity of 3-fluoro-d(+)- and 1(-)-tyrosine.", "content": "The toxicity of 3-fluoro-d(+)- and 1(-)-tyrosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995011"}
{"pmid": "20995012", "title": "Synthesis of 2,4-dichloropropiophenone.", "content": "Synthesis of 2,4-dichloropropiophenone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995012"}
{"pmid": "20995013", "title": "Unsaturated alcohol esters of the 9,10-dihydroxystearic acids; preparation of elaidyl alcohol.", "content": "Unsaturated alcohol esters of the 9,10-dihydroxystearic acids; preparation of elaidyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995013"}
{"pmid": "20995015", "title": "Kostecka's operation for the correction of mandibular prognathism.", "content": "Kostecka's operation for the correction of mandibular prognathism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995015"}
{"pmid": "20995014", "title": "The application to civilian practice of some dental lessons of the last war.", "content": "The application to civilian practice of some dental lessons of the last war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995014"}
{"pmid": "20995016", "title": "Dentistry in a P. o. W. camp in the Far East.", "content": "Dentistry in a P. o. W. camp in the Far East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995016"}
{"pmid": "20995017", "title": "Treatment of fibrous ankylosis by condyle removal.", "content": "Treatment of fibrous ankylosis by condyle removal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995017"}
{"pmid": "20995018", "title": "Acrylics; techniques and uses.", "content": "Acrylics; techniques and uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995018"}
{"pmid": "20995019", "title": "Intraosseous metal implants for denture stabilization.", "content": "Intraosseous metal implants for denture stabilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995019"}
{"pmid": "20995020", "title": "Disharmony between centric relation and centric occlusion as a factor in producing improper tooth wear and trauma.", "content": "Disharmony between centric relation and centric occlusion as a factor in producing improper tooth wear and trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995020"}
{"pmid": "20995022", "title": "The dentist's responsibility in tumors of the oral cavity.", "content": "The dentist's responsibility in tumors of the oral cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995022"}
{"pmid": "20995023", "title": "An upper and lower full denture impression technique.", "content": "An upper and lower full denture impression technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995023"}
{"pmid": "20995024", "title": "Dental health in the Minnesota Department of Health.", "content": "Dental health in the Minnesota Department of Health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995024"}
{"pmid": "20995025", "title": "Supernumerary tooth bud which developed into a cyst.", "content": "Supernumerary tooth bud which developed into a cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995025"}
{"pmid": "20995026", "title": "One hundred and fifty years of dentistry.", "content": "One hundred and fifty years of dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995026"}
{"pmid": "20995021", "title": "Penicillin, its use and abuse.", "content": "Penicillin, its use and abuse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995021"}
{"pmid": "20995028", "title": "Treatment of juvenile patients.", "content": "Treatment of juvenile patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995028"}
{"pmid": "20995027", "title": "The future of dentistry as a health service.", "content": "The future of dentistry as a health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995027"}
{"pmid": "20995029", "title": "Preventive dentistry.", "content": "Preventive dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995029"}
{"pmid": "20995030", "title": "Orthodontics and the dental hygienist.", "content": "Orthodontics and the dental hygienist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995030"}
{"pmid": "20995032", "title": "Scleroderma of the face involving the gingiva.", "content": "Scleroderma of the face involving the gingiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995032"}
{"pmid": "20995031", "title": "Treatment of basal cell epithelioma by injection of tissue extracts.", "content": "Treatment of basal cell epithelioma by injection of tissue extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995031"}
{"pmid": "20995033", "title": "Uses and abuses of penicillin in dermatology.", "content": "Uses and abuses of penicillin in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995033"}
{"pmid": "20995034", "title": "Etiologic considerations of keratosis blennorrhagica; report of a case in which penicillin was used.", "content": "Etiologic considerations of keratosis blennorrhagica; report of a case in which penicillin was used.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995034"}
{"pmid": "20995035", "title": "Recurrent genito-oral aphthosis and uveitis with hypopyon (Behcet's syndrome).", "content": "Recurrent genito-oral aphthosis and uveitis with hypopyon (Behcet's syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995035"}
{"pmid": "20995036", "title": "Acute lupus erythematosus disseminatus treated with penicillin.", "content": "Acute lupus erythematosus disseminatus treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995036"}
{"pmid": "20995037", "title": "A device of value for roentgen ray epilation.", "content": "A device of value for roentgen ray epilation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995037"}
{"pmid": "20995038", "title": "Lymphangioma circumscriptum; successful results of treatment with solid carbon dioxide.", "content": "Lymphangioma circumscriptum; successful results of treatment with solid carbon dioxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995038"}
{"pmid": "20995039", "title": "A yaws clinic in New Georgia.", "content": "A yaws clinic in New Georgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995039"}
{"pmid": "20995041", "title": "Sporotrichosis.", "content": "Sporotrichosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995041"}
{"pmid": "20995040", "title": "Dermatitis due to preparation and administration of penicillin solution.", "content": "Dermatitis due to preparation and administration of penicillin solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995040"}
{"pmid": "20995042", "title": "A formula for cryotherapy for acne and postacne scarring.", "content": "A formula for cryotherapy for acne and postacne scarring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995042"}
{"pmid": "20995043", "title": "Epilation by electrodesiccation of hairs of the scalp infected by fungi.", "content": "Epilation by electrodesiccation of hairs of the scalp infected by fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995043"}
{"pmid": "20995044", "title": "A case for diagnosis (acanthosis nigricans?).", "content": "A case for diagnosis (acanthosis nigricans?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995044"}
{"pmid": "20995045", "title": "Glomus tumor.", "content": "Glomus tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995045"}
{"pmid": "20995046", "title": "A case for diagnosis (atrophic lichen planus?).", "content": "A case for diagnosis (atrophic lichen planus?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995046"}
{"pmid": "20995047", "title": "A case for diagnosis (lupus erythematosus?).", "content": "A case for diagnosis (lupus erythematosus?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995047"}
{"pmid": "20995048", "title": "Lymphatic metastasis of a cutaneous epithelioma.", "content": "Lymphatic metastasis of a cutaneous epithelioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995048"}
{"pmid": "20995049", "title": "A case for diagnosis (Vincent's infection?).", "content": "A case for diagnosis (Vincent's infection?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995049"}
{"pmid": "20995050", "title": "Fox-Fordyce disease.", "content": "Fox-Fordyce disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995050"}
{"pmid": "20995051", "title": "Melanoma of the heel.", "content": "Melanoma of the heel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995051"}
{"pmid": "20995052", "title": "Exudative dermatitis (?).", "content": "Exudative dermatitis (?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995052"}
{"pmid": "20995053", "title": "Severe stomatitis.", "content": "Severe stomatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995053"}
{"pmid": "20995054", "title": "Giant nevus pigmentosus and verrucosus of the thigh treated by complete excision and primary grafting.", "content": "Giant nevus pigmentosus and verrucosus of the thigh treated by complete excision and primary grafting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995054"}
{"pmid": "20995055", "title": "Rhinosporidiosis.", "content": "Rhinosporidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995055"}
{"pmid": "20995057", "title": "Idiopathic multiple pigmented sarcoma (Kaposi?).", "content": "Idiopathic multiple pigmented sarcoma (Kaposi?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995057"}
{"pmid": "20995056", "title": "A case for diagnosis (periarteritis nodosa?).", "content": "A case for diagnosis (periarteritis nodosa?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995056"}
{"pmid": "20995058", "title": "Pemphigus erythematosus (?).", "content": "Pemphigus erythematosus (?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995058"}
{"pmid": "20995059", "title": "Seborrheic dermatitis with a decided palpebral involvement.", "content": "Seborrheic dermatitis with a decided palpebral involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995059"}
{"pmid": "20995060", "title": "Ainhum.", "content": "Ainhum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995060"}
{"pmid": "20995061", "title": "A case for diagnosis [sarcoid].", "content": "A case for diagnosis [sarcoid].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995061"}
{"pmid": "20995062", "title": "Familial lentigines.", "content": "Familial lentigines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995062"}
{"pmid": "20995063", "title": "Nevus pigmentosus lateralis.", "content": "Nevus pigmentosus lateralis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995063"}
{"pmid": "20995064", "title": "Erythema annulare centrifugum.", "content": "Erythema annulare centrifugum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995064"}
{"pmid": "20995065", "title": "Cutis hyperelastica.", "content": "Cutis hyperelastica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995065"}
{"pmid": "20995066", "title": "Pityriasis rubra pilaris.", "content": "Pityriasis rubra pilaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995066"}
{"pmid": "20995067", "title": "Tinea capitis in an adult.", "content": "Tinea capitis in an adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995067"}
{"pmid": "20995068", "title": "Vesiculobullous eruption involving vitiliginous areas of the perivulval and perianal regions.", "content": "Vesiculobullous eruption involving vitiliginous areas of the perivulval and perianal regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995068"}
{"pmid": "20995069", "title": "Two cases for diagnosis (unguis incarnatus?) in a brother and sister.", "content": "Two cases for diagnosis (unguis incarnatus?) in a brother and sister.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995069"}
{"pmid": "20995070", "title": "Pyoderma faciale; unimproved by local and parenteral penicillin therapy.", "content": "Pyoderma faciale; unimproved by local and parenteral penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995070"}
{"pmid": "20995072", "title": "A case for diagnosis (dermatitis factitia; tuberculid?).", "content": "A case for diagnosis (dermatitis factitia; tuberculid?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995072"}
{"pmid": "20995071", "title": "Tinea capitis, without alopecia.", "content": "Tinea capitis, without alopecia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995071"}
{"pmid": "20995073", "title": "Mycosis fungoides.", "content": "Mycosis fungoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995073"}
{"pmid": "20995074", "title": "Lupus erythematosus of unusual type (morphea-like epithelioma?).", "content": "Lupus erythematosus of unusual type (morphea-like epithelioma?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995074"}
{"pmid": "20995075", "title": "Epidermolysis bullosa.", "content": "Epidermolysis bullosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995075"}
{"pmid": "20995077", "title": "Linkage studies of awn in cultivated rice (Oryza sativa L.).", "content": "Linkage studies of awn in cultivated rice (Oryza sativa L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995077"}
{"pmid": "20995076", "title": "Genetical and cytological studies of Musa; the formation of polyploid spores.", "content": "Genetical and cytological studies of Musa; the formation of polyploid spores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995076"}
{"pmid": "20995078", "title": "On the occurrence and significance of deleterious genes in cotton.", "content": "On the occurrence and significance of deleterious genes in cotton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995078"}
{"pmid": "20995079", "title": "Fat colour and fur colour in different varieties of rabbit.", "content": "Fat colour and fur colour in different varieties of rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995079"}
{"pmid": "20995080", "title": "The inheritance of brown lint in new world cottons.", "content": "The inheritance of brown lint in new world cottons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995080"}
{"pmid": "20995082", "title": "Twin studies on the psychopathology of suicide.", "content": "Twin studies on the psychopathology of suicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995082"}
{"pmid": "20995081", "title": "Yaks and yak-cattle hybrids in Asia.", "content": "Yaks and yak-cattle hybrids in Asia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995081"}
{"pmid": "20995084", "title": "The inheritance of flexed fingers.", "content": "The inheritance of flexed fingers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995084"}
{"pmid": "20995083", "title": "A recurrent mutation of dominant achondroplasia in cattle.", "content": "A recurrent mutation of dominant achondroplasia in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995083"}
{"pmid": "20995087", "title": "CARE of the dead; planning and equipping the hospital mortuary.", "content": "CARE of the dead; planning and equipping the hospital mortuary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995087"}
{"pmid": "20995088", "title": "Engineering in hospitals; mechanised signalling system.", "content": "Engineering in hospitals; mechanised signalling system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995088"}
{"pmid": "20995089", "title": "Mobile dental units; American Navy's new service.", "content": "Mobile dental units; American Navy's new service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995089"}
{"pmid": "20995096", "title": "The safe use of solvents for synthetic rubbers.", "content": "The safe use of solvents for synthetic rubbers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995096"}
{"pmid": "20995097", "title": "Some diagnostic problems in occupational diseases.", "content": "Some diagnostic problems in occupational diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995097"}
{"pmid": "20995101", "title": "The first two years of social insurance in Mexico.", "content": "The first two years of social insurance in Mexico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995101"}
{"pmid": "20995091", "title": "Treatment of alcoholism.", "content": "Treatment of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995091"}
{"pmid": "20995090", "title": "Social and medical aspects of alcoholism.", "content": "Social and medical aspects of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995090"}
{"pmid": "20995106", "title": "Further observations on the enhanced fragility of red cells in malaria patients.", "content": "Further observations on the enhanced fragility of red cells in malaria patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995106"}
{"pmid": "20995107", "title": "Penicillin through duodenal tube in gastric surgery.", "content": "Penicillin through duodenal tube in gastric surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995107"}
{"pmid": "20995108", "title": "The influence of buffer solutions on gastric acidity.", "content": "The influence of buffer solutions on gastric acidity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995108"}
{"pmid": "20995098", "title": "Legal developments of 1945 respecting industrial health.", "content": "Legal developments of 1945 respecting industrial health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995098"}
{"pmid": "20995109", "title": "A rare case of thrombangitis obliterans.", "content": "A rare case of thrombangitis obliterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995109"}
{"pmid": "20995110", "title": "Estimation of potassium.", "content": "Estimation of potassium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995110"}
{"pmid": "20995099", "title": "Canada and compensation.", "content": "Canada and compensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995099"}
{"pmid": "20995092", "title": "Alcoholic potentials.", "content": "Alcoholic potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995092"}
{"pmid": "20995100", "title": "Health insurance to compensate for wage loss.", "content": "Health insurance to compensate for wage loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995100"}
{"pmid": "20995111", "title": "To read, to weep and to ponder.", "content": "To read, to weep and to ponder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995111"}
{"pmid": "20995115", "title": "Development and metabolism of copper-deficient oat plants.", "content": "Development and metabolism of copper-deficient oat plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995115"}
{"pmid": "20995116", "title": "Alloxan diabetes in the sheep.", "content": "Alloxan diabetes in the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995116"}
{"pmid": "20995117", "title": "A herpes skin test reagent from amniotic fluid.", "content": "A herpes skin test reagent from amniotic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995117"}
{"pmid": "20995118", "title": "On some properties of cruoratin and its relationship to pseudo-haematin.", "content": "On some properties of cruoratin and its relationship to pseudo-haematin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995118"}
{"pmid": "20995119", "title": "The effects of mineral nutrients on the concentration of ascorbic acid in legumes and two leaf vegetables.", "content": "The effects of mineral nutrients on the concentration of ascorbic acid in legumes and two leaf vegetables.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995119"}
{"pmid": "20995120", "title": "The effect of storage on the riboflavin content of urine.", "content": "The effect of storage on the riboflavin content of urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995120"}
{"pmid": "20995121", "title": "The influence of food on the size of two strains of Calandra oryzae L.", "content": "The influence of food on the size of two strains of Calandra oryzae L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995121"}
{"pmid": "20995122", "title": "Mumps; virus haemagglutination and serological reactions.", "content": "Mumps; virus haemagglutination and serological reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995122"}
{"pmid": "20995123", "title": "The biological activity of a substance resembling gliotoxin produced by a strain of Aspergillus fumigatus.", "content": "The biological activity of a substance resembling gliotoxin produced by a strain of Aspergillus fumigatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995123"}
{"pmid": "20995124", "title": "Chemical analysis demonstrating the possible identity of aspergilin with gliotoxin.", "content": "Chemical analysis demonstrating the possible identity of aspergilin with gliotoxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995124"}
{"pmid": "20995125", "title": "Studies on the cultivation in vitro of normal and pathological guinea-pig bone marrow.", "content": "Studies on the cultivation in vitro of normal and pathological guinea-pig bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995125"}
{"pmid": "20995126", "title": "The effect of morphine on dye concentration curves for plasma volume determination in dogs.", "content": "The effect of morphine on dye concentration curves for plasma volume determination in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995126"}
{"pmid": "20995127", "title": "An electron microscope investigation of the cuticle of wool.", "content": "An electron microscope investigation of the cuticle of wool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995127"}
{"pmid": "20995129", "title": "The place of genetics in clinical medicine.", "content": "The place of genetics in clinical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995129"}
{"pmid": "20995128", "title": "CONGENITAL factors in disease.", "content": "CONGENITAL factors in disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995128"}
{"pmid": "20995130", "title": "Vital statistics of still-births and neonatal deaths.", "content": "Vital statistics of still-births and neonatal deaths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995130"}
{"pmid": "20995131", "title": "The pathology of still-birth and neonatal death; a review of 1053 cases.", "content": "The pathology of still-birth and neonatal death; a review of 1053 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995131"}
{"pmid": "20995132", "title": "The post-mortem examination of the newborn infant.", "content": "The post-mortem examination of the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995132"}
{"pmid": "20995133", "title": "A summary of present knowledge of human blood-groups, with special reference to serological incompatibility as a cause of congenital disease.", "content": "A summary of present knowledge of human blood-groups, with special reference to serological incompatibility as a cause of congenital disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995133"}
{"pmid": "20995134", "title": "Maternal rubella as a cause of congenital defects.", "content": "Maternal rubella as a cause of congenital defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995134"}
{"pmid": "20995136", "title": "Blindness and visual defect of congenital origin.", "content": "Blindness and visual defect of congenital origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995136"}
{"pmid": "20995137", "title": "The genetics of cancer, a short review of experimental findings.", "content": "The genetics of cancer, a short review of experimental findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995137"}
{"pmid": "20995135", "title": "Some applications of prenatal nutrition to infant development.", "content": "Some applications of prenatal nutrition to infant development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995135"}
{"pmid": "20995138", "title": "Mental defect; recent researches.", "content": "Mental defect; recent researches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995138"}
{"pmid": "20995140", "title": "Leiden and Edinburgh; a medical partnership.", "content": "Leiden and Edinburgh; a medical partnership.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995140"}
{"pmid": "20995141", "title": "Properties and uses of DDT.", "content": "Properties and uses of DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995141"}
{"pmid": "20995142", "title": "Curative properties of rare earths found in B. C. peloid deposits.", "content": "Curative properties of rare earths found in B. C. peloid deposits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995142"}
{"pmid": "20995143", "title": "Rheumatic fever.", "content": "Rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995143"}
{"pmid": "20995144", "title": "Infant welfare in Australia.", "content": "Infant welfare in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995144"}
{"pmid": "20995145", "title": "FIGHTING tropical diseases; mass treatment of population.", "content": "FIGHTING tropical diseases; mass treatment of population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995145"}
{"pmid": "20995146", "title": "Wartime invention helps deaf children.", "content": "Wartime invention helps deaf children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995146"}
{"pmid": "20995147", "title": "Health survey.", "content": "Health survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995147"}
{"pmid": "20995148", "title": "Irregularities of the heart.", "content": "Irregularities of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995148"}
{"pmid": "20995149", "title": "Collapse therapy in bilateral A. P.", "content": "Collapse therapy in bilateral A. P.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995149"}
{"pmid": "20995150", "title": "How Australia expanded drug production.", "content": "How Australia expanded drug production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995150"}
{"pmid": "20995151", "title": "The diarrheas and the general practitioner.", "content": "The diarrheas and the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995151"}
{"pmid": "20995152", "title": "A scale for determining heart rate in electrocardiograms.", "content": "A scale for determining heart rate in electrocardiograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995152"}
{"pmid": "20995153", "title": "Commonplace reminders to the general anesthetist.", "content": "Commonplace reminders to the general anesthetist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995153"}
{"pmid": "20995154", "title": "X-ray treatment of goiter.", "content": "X-ray treatment of goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995154"}
{"pmid": "20995155", "title": "Rheumatic fever; orthopedic conditions causing confusion in diagnosis.", "content": "Rheumatic fever; orthopedic conditions causing confusion in diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995155"}
{"pmid": "20995156", "title": "Early manifestations of mental disorder.", "content": "Early manifestations of mental disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995156"}
{"pmid": "20995157", "title": "The use of small general hospitals for communicable patients.", "content": "The use of small general hospitals for communicable patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995157"}
{"pmid": "20995158", "title": "Conditioned reflex treatment for alcohol addicts.", "content": "Conditioned reflex treatment for alcohol addicts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995158"}
{"pmid": "20995159", "title": "Intermittent proteinuria (albuminuria) of young adults; its benign nature.", "content": "Intermittent proteinuria (albuminuria) of young adults; its benign nature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995159"}
{"pmid": "20995160", "title": "Uses and untoward reactions of sulfonamides in dermatology.", "content": "Uses and untoward reactions of sulfonamides in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995160"}
{"pmid": "20995161", "title": "Antivivisectionists.", "content": "Antivivisectionists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995161"}
{"pmid": "20995162", "title": "Nutrition during pregnancy.", "content": "Nutrition during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995162"}
{"pmid": "20995163", "title": "Physiological basis of electric convulsive therapy.", "content": "Physiological basis of electric convulsive therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995163"}
{"pmid": "20995164", "title": "The use of curare in shock therapy in cases complicated by pathological skeletal conditions.", "content": "The use of curare in shock therapy in cases complicated by pathological skeletal conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995164"}
{"pmid": "20995165", "title": "Fluorine, a deterrent in dental caries.", "content": "Fluorine, a deterrent in dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995165"}
{"pmid": "20995166", "title": "Periarteritis nodosa (neuromuscular type).", "content": "Periarteritis nodosa (neuromuscular type).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995166"}
{"pmid": "20995167", "title": "The optic neuritides.", "content": "The optic neuritides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995167"}
{"pmid": "20995168", "title": "The tumor clinic in a small hospital.", "content": "The tumor clinic in a small hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995168"}
{"pmid": "20995169", "title": "The significance of comprehensive medical care.", "content": "The significance of comprehensive medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995169"}
{"pmid": "20995170", "title": "I transplanted hearts.", "content": "I transplanted hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995170"}
{"pmid": "20995171", "title": "Sex adjustment in marriage.", "content": "Sex adjustment in marriage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995171"}
{"pmid": "20995172", "title": "The effect on the anopheline fauna of cultivation of swamps in Kigezi district, Uganda.", "content": "The effect on the anopheline fauna of cultivation of swamps in Kigezi district, Uganda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995172"}
{"pmid": "20995173", "title": "Two cases of disseminated sclerosis in African natives.", "content": "Two cases of disseminated sclerosis in African natives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995173"}
{"pmid": "20995174", "title": "Acute primary encephalomyelitis of South Central Africa.", "content": "Acute primary encephalomyelitis of South Central Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995174"}
{"pmid": "20995175", "title": "Tuberculosis of the skin in East Africans; with a report of two cases.", "content": "Tuberculosis of the skin in East Africans; with a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995175"}
{"pmid": "20995176", "title": "A lithopaedion.", "content": "A lithopaedion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995176"}
{"pmid": "20995177", "title": "Laboratory tests of schistosomiasis.", "content": "Laboratory tests of schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995177"}
{"pmid": "20995199", "title": "Effect of solar eclipse upon the eye.", "content": "Effect of solar eclipse upon the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995199"}
{"pmid": "20995191", "title": "Electrocardiographic response to exercise in 100 normal subjects.", "content": "Electrocardiographic response to exercise in 100 normal subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995191"}
{"pmid": "20995200", "title": "Disorders of blood pressure.", "content": "Disorders of blood pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995200"}
{"pmid": "20995201", "title": "Inguinal hernia.", "content": "Inguinal hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995201"}
{"pmid": "20995202", "title": "Infant feeding.", "content": "Infant feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995202"}
{"pmid": "20995192", "title": "The Sulkowitch test in the diagnosis and management of hypocalcemic tetany of newborns and infants.", "content": "The Sulkowitch test in the diagnosis and management of hypocalcemic tetany of newborns and infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995192"}
{"pmid": "20995196", "title": "Plantation visiting nursing.", "content": "Plantation visiting nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995196"}
{"pmid": "20995203", "title": "Maternity and child welfare (in an industrial town).", "content": "Maternity and child welfare (in an industrial town).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995203"}
{"pmid": "20995194", "title": "Beef tapeworm in Filipinos.", "content": "Beef tapeworm in Filipinos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995194"}
{"pmid": "20995204", "title": "Tuberculoid leprosy.", "content": "Tuberculoid leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995204"}
{"pmid": "20995206", "title": "Observations on Bhore Committee's Report.", "content": "Observations on Bhore Committee's Report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995206"}
{"pmid": "20995193", "title": "Extra-uterine abdominal pregnancy review and case report.", "content": "Extra-uterine abdominal pregnancy review and case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995193"}
{"pmid": "20995205", "title": "Accidental poisoning by carbon monoxide (carbonic oxide gas).", "content": "Accidental poisoning by carbon monoxide (carbonic oxide gas).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995205"}
{"pmid": "20995197", "title": "School nursing.", "content": "School nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995197"}
{"pmid": "20995207", "title": "Presbyopia or old age sight.", "content": "Presbyopia or old age sight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995207"}
{"pmid": "20995198", "title": "Public Health Nursing Bureau.", "content": "Public Health Nursing Bureau.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995198"}
{"pmid": "20995208", "title": "The treatment of cholera and acute gastro-enteritis.", "content": "The treatment of cholera and acute gastro-enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995208"}
{"pmid": "20995209", "title": "Crime; its relation with climate, age etc., and a short note on the psychology of crime.", "content": "Crime; its relation with climate, age etc., and a short note on the psychology of crime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995209"}
{"pmid": "20995210", "title": "Perspiration.", "content": "Perspiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995210"}
{"pmid": "20995211", "title": "Will the family doctor survive?", "content": "Will the family doctor survive?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995211"}
{"pmid": "20995212", "title": "Streptomycin in the treatment of infections.", "content": "Streptomycin in the treatment of infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995212"}
{"pmid": "20995195", "title": "Industrial nursing.", "content": "Industrial nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995195"}
{"pmid": "20995213", "title": "Fatal aplastic anemia following use of tridione and a hydantoin.", "content": "Fatal aplastic anemia following use of tridione and a hydantoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995213"}
{"pmid": "20995214", "title": "Aplastic anemia and agranulocytosis following tridione.", "content": "Aplastic anemia and agranulocytosis following tridione.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995214"}
{"pmid": "20995215", "title": "Development of streptomycin resistance during treatment.", "content": "Development of streptomycin resistance during treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995215"}
{"pmid": "20995216", "title": "Streptomycin in tularemia.", "content": "Streptomycin in tularemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995216"}
{"pmid": "20995217", "title": "Aortectomy for thoracic aneurysm.", "content": "Aortectomy for thoracic aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995217"}
{"pmid": "20995218", "title": "Inhibition of phosphorylation of glucose in mouse brains by viruses and its prevention by preparations of diphosphopyridine nucleotide.", "content": "Inhibition of phosphorylation of glucose in mouse brains by viruses and its prevention by preparations of diphosphopyridine nucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995218"}
{"pmid": "20995219", "title": "Effect of in vitro cultivation on the pathogenicity of Venezuelan equine encephalomyelitis virus.", "content": "Effect of in vitro cultivation on the pathogenicity of Venezuelan equine encephalomyelitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995219"}
{"pmid": "20995220", "title": "The production of chronic glomerulonephritis in rats by the injection of rabbit anti-rat-placenta serum.", "content": "The production of chronic glomerulonephritis in rats by the injection of rabbit anti-rat-placenta serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995220"}
{"pmid": "20995221", "title": "Studies on the Flexner group of dysentery bacilli; the serological and toxic properties of the somatic antigens.", "content": "Studies on the Flexner group of dysentery bacilli; the serological and toxic properties of the somatic antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995221"}
{"pmid": "20995222", "title": "Studies on the Flexner group of dysentery bacilli; a quantitative study of the serological cross-reactions.", "content": "Studies on the Flexner group of dysentery bacilli; a quantitative study of the serological cross-reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995222"}
{"pmid": "20995223", "title": "Further studies on effects of tissue extracts on Staphylococcus aureus.", "content": "Further studies on effects of tissue extracts on Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995223"}
{"pmid": "20995224", "title": "Reactions of monkeys to experimentally induced Streptococcus hemolyticus, group C, infection; an analysis of the relative rôles of humoral and cellular immunity under conditions of optimal or deficient nutrition.", "content": "Reactions of monkeys to experimentally induced Streptococcus hemolyticus, group C, infection; an analysis of the relative rôles of humoral and cellular immunity under conditions of optimal or deficient nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995224"}
{"pmid": "20995225", "title": "Peripheral vascular disease.", "content": "Peripheral vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995225"}
{"pmid": "20995226", "title": "Origin and progress of the Florida Radiological Society.", "content": "Origin and progress of the Florida Radiological Society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995226"}
{"pmid": "20995227", "title": "Infectious (viral) hepatitis.", "content": "Infectious (viral) hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995227"}
{"pmid": "20995228", "title": "The treatment of burns.", "content": "The treatment of burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995228"}
{"pmid": "20995229", "title": "Papilledema.", "content": "Papilledema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995229"}
{"pmid": "20995230", "title": "Principles of military surgery applicable to civil practice with especial reference to acute traumatic lesions.", "content": "Principles of military surgery applicable to civil practice with especial reference to acute traumatic lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995230"}
{"pmid": "20995231", "title": "Eosinophilic granuloma of bone, with report of a case.", "content": "Eosinophilic granuloma of bone, with report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995231"}
{"pmid": "20995232", "title": "The elimination of human reaction-producing material from horse-derived antiserums: an electrical method.", "content": "The elimination of human reaction-producing material from horse-derived antiserums: an electrical method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995232"}
{"pmid": "20995233", "title": "A study of abnormal T waves in patients presenting no evidence of organic heart disease.", "content": "A study of abnormal T waves in patients presenting no evidence of organic heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995233"}
{"pmid": "20995234", "title": "Observations on the effect of theophylline aminoisobutanol in experimental heart failure.", "content": "Observations on the effect of theophylline aminoisobutanol in experimental heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995234"}
{"pmid": "20995236", "title": "Stimulation of the central nervous system by curare (intocostrin).", "content": "Stimulation of the central nervous system by curare (intocostrin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995236"}
{"pmid": "20995235", "title": "The effect of theophylline aminoisobutanol on the circulation in congestive heart failure.", "content": "The effect of theophylline aminoisobutanol on the circulation in congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995235"}
{"pmid": "20995238", "title": "Hematologic survey of repatriated American military personnel.", "content": "Hematologic survey of repatriated American military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995238"}
{"pmid": "20995237", "title": "Hemoglobin levels in specific race, age, and sex groups of a normal North Carolina population.", "content": "Hemoglobin levels in specific race, age, and sex groups of a normal North Carolina population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995237"}
{"pmid": "20995239", "title": "Absorption and excretion of sulfathiadiazole and sulfamethylthiadiazole after oral administration in human beings.", "content": "Absorption and excretion of sulfathiadiazole and sulfamethylthiadiazole after oral administration in human beings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995239"}
{"pmid": "20995240", "title": "The quantitative determination of the thymol turbidity reaction of serum.", "content": "The quantitative determination of the thymol turbidity reaction of serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995240"}
{"pmid": "20995241", "title": "Semiquantitative estimation of bilirubin in the urine by means of the barium-strip modification of Harrison's test.", "content": "Semiquantitative estimation of bilirubin in the urine by means of the barium-strip modification of Harrison's test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995241"}
{"pmid": "20995242", "title": "Applicability of the Biuret reaction to the determination of serum albumin by methanol precipitation.", "content": "Applicability of the Biuret reaction to the determination of serum albumin by methanol precipitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995242"}
{"pmid": "20995243", "title": "Oxygen consumption and drug action: a method for measurement of the respiration of aquatic animals.", "content": "Oxygen consumption and drug action: a method for measurement of the respiration of aquatic animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995243"}
{"pmid": "20995244", "title": "The methylene blue test for bilirubinuria: clinical and spectrophotometric observations.", "content": "The methylene blue test for bilirubinuria: clinical and spectrophotometric observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995244"}
{"pmid": "20995246", "title": "Water balance; normal mechanism, methods of administration, dangers.", "content": "Water balance; normal mechanism, methods of administration, dangers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995246"}
{"pmid": "20995245", "title": "A simple method of determining the specific gravity of small samples of urine.", "content": "A simple method of determining the specific gravity of small samples of urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995245"}
{"pmid": "20995247", "title": "Water and electrolyte balance in surgical patients.", "content": "Water and electrolyte balance in surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995247"}
{"pmid": "20995248", "title": "Medical problems of the acid-base balance.", "content": "Medical problems of the acid-base balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995248"}
{"pmid": "20995249", "title": "Thyroid dysfunction.", "content": "Thyroid dysfunction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995249"}
{"pmid": "20995250", "title": "Visual defects in prisoners-of-war, from the Far East.", "content": "Visual defects in prisoners-of-war, from the Far East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995250"}
{"pmid": "20995251", "title": "Intrathecal streptomycin in meningitis; clinical trial in tuberculous, coliform, and other infections.", "content": "Intrathecal streptomycin in meningitis; clinical trial in tuberculous, coliform, and other infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995251"}
{"pmid": "20995253", "title": "Benadryl in hay-fever; a note on its action.", "content": "Benadryl in hay-fever; a note on its action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995253"}
{"pmid": "20995252", "title": "Folic acid in the treatment of pernicious anaemia.", "content": "Folic acid in the treatment of pernicious anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995252"}
{"pmid": "20995254", "title": "Fat-digestion in sprue; studies by intestinal intubation.", "content": "Fat-digestion in sprue; studies by intestinal intubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995254"}
{"pmid": "20995255", "title": "Retractor for varicose vein surgery.", "content": "Retractor for varicose vein surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995255"}
{"pmid": "20995256", "title": "INDEX-CATALOGUE of the Army Medical Library.", "content": "INDEX-CATALOGUE of the Army Medical Library.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995256"}
{"pmid": "20995257", "title": "Epidemiology and the psychosomatic affections; a study in social medicine.", "content": "Epidemiology and the psychosomatic affections; a study in social medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995257"}
{"pmid": "20995258", "title": "Variation in the female pelvis.", "content": "Variation in the female pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995258"}
{"pmid": "20995259", "title": "Mass immunisation of a force in the field against diphtheria.", "content": "Mass immunisation of a force in the field against diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995259"}
{"pmid": "20995260", "title": "Erysipeloid.", "content": "Erysipeloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995260"}
{"pmid": "20995261", "title": "Direct test for blocking antibody in treated hay-fever.", "content": "Direct test for blocking antibody in treated hay-fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995261"}
{"pmid": "20995262", "title": "Grey hair in ill-nourished children.", "content": "Grey hair in ill-nourished children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995262"}
{"pmid": "20995263", "title": "Zygomatic traction for fracture of cervical spine.", "content": "Zygomatic traction for fracture of cervical spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995263"}
{"pmid": "20995264", "title": "PHYSIOLOGY OF convalescence.", "content": "PHYSIOLOGY OF convalescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995264"}
{"pmid": "20995265", "title": "Anoxia and renal function.", "content": "Anoxia and renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995265"}
{"pmid": "20995266", "title": "Urea-formaldehyde resins in orthopaedic surgery.", "content": "Urea-formaldehyde resins in orthopaedic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995266"}
{"pmid": "20995268", "title": "Inhaled penicillin in bronchial infections.", "content": "Inhaled penicillin in bronchial infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995268"}
{"pmid": "20995267", "title": "Penicillin inhalation in pulmonary disease.", "content": "Penicillin inhalation in pulmonary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995267"}
{"pmid": "20995269", "title": "Casein hydrolysate; a supplementary food for premature infants.", "content": "Casein hydrolysate; a supplementary food for premature infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995269"}
{"pmid": "20995270", "title": "Acute abdominal lymphadenitis in children.", "content": "Acute abdominal lymphadenitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995270"}
{"pmid": "20995271", "title": "Artificial pneumoperitoneum, as an emergency measure in severe haemoptysis.", "content": "Artificial pneumoperitoneum, as an emergency measure in severe haemoptysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995271"}
{"pmid": "20995272", "title": "Poisoning by D.D.T. emulsion.", "content": "Poisoning by D.D.T. emulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995272"}
{"pmid": "20995273", "title": "Tropical eosinophilia in Egypt.", "content": "Tropical eosinophilia in Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995273"}
{"pmid": "20995274", "title": "Renal pathology in the light of recent neurovascular studies.", "content": "Renal pathology in the light of recent neurovascular studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995274"}
{"pmid": "20995275", "title": "LESSER circulation of the kidney.", "content": "LESSER circulation of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995275"}
{"pmid": "20995276", "title": "Nutritional retrobulbar neuritis; nutritional optic neuropathy.", "content": "Nutritional retrobulbar neuritis; nutritional optic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995276"}
{"pmid": "20995277", "title": "MEDICAL education in Queensland.", "content": "MEDICAL education in Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995277"}
{"pmid": "20995278", "title": "TREATMENT of communicable diseases.", "content": "TREATMENT of communicable diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995278"}
{"pmid": "20995280", "title": "Painless treatment of ankylosed joints, a report of 19 years' study.", "content": "Painless treatment of ankylosed joints, a report of 19 years' study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995280"}
{"pmid": "20995279", "title": "Recent research on cholera.", "content": "Recent research on cholera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995279"}
{"pmid": "20995281", "title": "Felon.", "content": "Felon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995281"}
{"pmid": "20995282", "title": "JAPANESE activities in medical science.", "content": "JAPANESE activities in medical science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995282"}
{"pmid": "20995283", "title": "Domiciliary obstetrics.", "content": "Domiciliary obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995283"}
{"pmid": "20995284", "title": "Inhalation anesthesia.", "content": "Inhalation anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995284"}
{"pmid": "20995285", "title": "Intravenous anesthesia; from an orthopedic standpoint.", "content": "Intravenous anesthesia; from an orthopedic standpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995285"}
{"pmid": "20995286", "title": "Spinal analgesia.", "content": "Spinal analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995286"}
{"pmid": "20995287", "title": "Local and regional anesthesia.", "content": "Local and regional anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995287"}
{"pmid": "20995288", "title": "Removal of a polycystic kidney from a baby two months of age.", "content": "Removal of a polycystic kidney from a baby two months of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995288"}
{"pmid": "20995289", "title": "Myasthenia gravis of muscles of deglutition.", "content": "Myasthenia gravis of muscles of deglutition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995289"}
{"pmid": "20995290", "title": "Poliomyelitis; a review of its epidemiology with especial consideration of the autarcheological concept of immunity.", "content": "Poliomyelitis; a review of its epidemiology with especial consideration of the autarcheological concept of immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995290"}
{"pmid": "20995291", "title": "Leprosy.", "content": "Leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995291"}
{"pmid": "20995292", "title": "Surgical treatment of thrombophlebitis.", "content": "Surgical treatment of thrombophlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995292"}
{"pmid": "20995293", "title": "Anticoagulant therapy in post-operative thrombophlebitis and pulmonary embolism.", "content": "Anticoagulant therapy in post-operative thrombophlebitis and pulmonary embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995293"}
{"pmid": "20995294", "title": "Neonatal deaths following term deliveries, 1937-1945; cause and effect relationships.", "content": "Neonatal deaths following term deliveries, 1937-1945; cause and effect relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995294"}
{"pmid": "20995295", "title": "Subacute bacterial endocarditis with rupture of spleen.", "content": "Subacute bacterial endocarditis with rupture of spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995295"}
{"pmid": "20995296", "title": "Cholecystectomy; an analysis of 250 consecutive operations.", "content": "Cholecystectomy; an analysis of 250 consecutive operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995296"}
{"pmid": "20995297", "title": "Benign strictures of the extra-hepatic bile ducts at the University of Minnesota hospitals.", "content": "Benign strictures of the extra-hepatic bile ducts at the University of Minnesota hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995297"}
{"pmid": "20995298", "title": "Some findings in physical examinations.", "content": "Some findings in physical examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995298"}
{"pmid": "20995299", "title": "Varicose veins; evaluation and treatment.", "content": "Varicose veins; evaluation and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995299"}
{"pmid": "20995300", "title": "Diarrhea.", "content": "Diarrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995300"}
{"pmid": "20995301", "title": "The ophthalmoscope, an aid in diagnosis.", "content": "The ophthalmoscope, an aid in diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995301"}
{"pmid": "20995302", "title": "Surgery and allied methods in the treatment of cancer.", "content": "Surgery and allied methods in the treatment of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995302"}
{"pmid": "20995303", "title": "Saving the injured hand.", "content": "Saving the injured hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995303"}
{"pmid": "20995304", "title": "Present trends and future developments.", "content": "Present trends and future developments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995304"}
{"pmid": "20995305", "title": "Management of acute intestinal obstruction.", "content": "Management of acute intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995305"}
{"pmid": "20995306", "title": "Analytical survey of goiter management, University of Nebraska Hospital, 1935-1944.", "content": "Analytical survey of goiter management, University of Nebraska Hospital, 1935-1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995306"}
{"pmid": "20995307", "title": "Systemic causes of gastro-intestinal hemorrhages.", "content": "Systemic causes of gastro-intestinal hemorrhages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995307"}
{"pmid": "20995308", "title": "Esophageal and gastric hemorrhage.", "content": "Esophageal and gastric hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995308"}
{"pmid": "20995309", "title": "Hemorrhage from the small bowel.", "content": "Hemorrhage from the small bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995309"}
{"pmid": "20995310", "title": "Vincent's anginal infection of the throat.", "content": "Vincent's anginal infection of the throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995310"}
{"pmid": "20995311", "title": "The treatment of carcinoma of the bladder.", "content": "The treatment of carcinoma of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995311"}
{"pmid": "20995312", "title": "EMOTIONAL attitude greatest barrier to recovery from aphasia, SGO reports.", "content": "EMOTIONAL attitude greatest barrier to recovery from aphasia, SGO reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995312"}
{"pmid": "20995313", "title": "Medical adventures in Korea.", "content": "Medical adventures in Korea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995313"}
{"pmid": "20995314", "title": "Interlobar effusion associated with heart failure.", "content": "Interlobar effusion associated with heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995314"}
{"pmid": "20995315", "title": "Pregnancy in general paresis.", "content": "Pregnancy in general paresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995315"}
{"pmid": "20995317", "title": "Transurethral resection of the prostate; indications and contraindications.", "content": "Transurethral resection of the prostate; indications and contraindications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995317"}
{"pmid": "20995316", "title": "The principles of military surgery as applied to civilian practice.", "content": "The principles of military surgery as applied to civilian practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995316"}
{"pmid": "20995318", "title": "Thyrotoxicosis and its treatment with thiouracil.", "content": "Thyrotoxicosis and its treatment with thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995318"}
{"pmid": "20995319", "title": "PROMISCUITY; a psychiatric study.", "content": "PROMISCUITY; a psychiatric study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995319"}
{"pmid": "20995361", "title": "The surgical problem of intracranial aneurysm and related vascular lesions.", "content": "The surgical problem of intracranial aneurysm and related vascular lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995361"}
{"pmid": "20995362", "title": "Postoperative wound infections; an evaluation of factors concerned with the resistance of the tissues to infection.", "content": "Postoperative wound infections; an evaluation of factors concerned with the resistance of the tissues to infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995362"}
{"pmid": "20995363", "title": "Burns in children.", "content": "Burns in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995363"}
{"pmid": "20995364", "title": "An assessment of the value of the nitroprusside reaction for the determination of ketone bodies in urine.", "content": "An assessment of the value of the nitroprusside reaction for the determination of ketone bodies in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995364"}
{"pmid": "20995365", "title": "The effect of pavatrine (beta-diethylaminoethyl fluorene-9-carboxylate hydrochloride) on the sphincter of Oddi with studies on its toxicity.", "content": "The effect of pavatrine (beta-diethylaminoethyl fluorene-9-carboxylate hydrochloride) on the sphincter of Oddi with studies on its toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995365"}
{"pmid": "20995366", "title": "An unusual complication of pregnancy [colitis].", "content": "An unusual complication of pregnancy [colitis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995366"}
{"pmid": "20995367", "title": "Some observations on learning ability in the guinea pig.", "content": "Some observations on learning ability in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995367"}
{"pmid": "20995368", "title": "A study of 219 cases of peptic ulcer in a series of 2,301 consecutive necropsies.", "content": "A study of 219 cases of peptic ulcer in a series of 2,301 consecutive necropsies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995368"}
{"pmid": "20995369", "title": "Accessory tendinous (peroneal) origin of the first dorsal interosseous muscle; a study of 125 specimens of lower extremity.", "content": "Accessory tendinous (peroneal) origin of the first dorsal interosseous muscle; a study of 125 specimens of lower extremity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995369"}
{"pmid": "20995371", "title": "Pink disease.", "content": "Pink disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995371"}
{"pmid": "20995370", "title": "An artisan of living, Arthur Isaac Kendall.", "content": "An artisan of living, Arthur Isaac Kendall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995370"}
{"pmid": "20995372", "title": "An account of the foxglove.", "content": "An account of the foxglove.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995372"}
{"pmid": "20995373", "title": "A simple method of cure for flat foot.", "content": "A simple method of cure for flat foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995373"}
{"pmid": "20995374", "title": "Nitrous oxide for minor operations.", "content": "Nitrous oxide for minor operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995374"}
{"pmid": "20995375", "title": "Ovarian tumours associated with sex characteristics.", "content": "Ovarian tumours associated with sex characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995375"}
{"pmid": "20995376", "title": "Child life during Malta's siege.", "content": "Child life during Malta's siege.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995376"}
{"pmid": "20995377", "title": "The social background of ill-health.", "content": "The social background of ill-health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995377"}
{"pmid": "20995378", "title": "The absorption, transport and storage of iron.", "content": "The absorption, transport and storage of iron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995378"}
{"pmid": "20995379", "title": "Colonial medicine; extracts from strange places and strange peoples relating to medicine in the Fiji.", "content": "Colonial medicine; extracts from strange places and strange peoples relating to medicine in the Fiji.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995379"}
{"pmid": "20995380", "title": "The digestive tract in medical history.", "content": "The digestive tract in medical history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995380"}
{"pmid": "20995381", "title": "Thyrotoxicosis.", "content": "Thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995381"}
{"pmid": "20995382", "title": "The psychological approach to illness.", "content": "The psychological approach to illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995382"}
{"pmid": "20995383", "title": "The artificial feeding of infants.", "content": "The artificial feeding of infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995383"}
{"pmid": "20995384", "title": "[ANOPHELES] West African souvenirs.", "content": "[ANOPHELES] West African souvenirs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995384"}
{"pmid": "20995385", "title": "Asphyxia neonatorum; probable etiological factors and their statistical figures.", "content": "Asphyxia neonatorum; probable etiological factors and their statistical figures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995385"}
{"pmid": "20995386", "title": "Mass radiography; its evaluation as a contribution to preventive medicine, particularly as regards tuberculosis.", "content": "Mass radiography; its evaluation as a contribution to preventive medicine, particularly as regards tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995386"}
{"pmid": "20995387", "title": "Some factors concerning sleep and wakefulness.", "content": "Some factors concerning sleep and wakefulness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995387"}
{"pmid": "20995388", "title": "A simple method for the cure of certain types of pain by rapid rhythmic movements.", "content": "A simple method for the cure of certain types of pain by rapid rhythmic movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995388"}
{"pmid": "20995389", "title": "The voluntary hospital system.", "content": "The voluntary hospital system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995389"}
{"pmid": "20995390", "title": "Gas gangrene.", "content": "Gas gangrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995390"}
{"pmid": "20995391", "title": "The oesophagus; a review of surgical progress.", "content": "The oesophagus; a review of surgical progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995391"}
{"pmid": "20995392", "title": "The surgery of the mid-Victorian period.", "content": "The surgery of the mid-Victorian period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995392"}
{"pmid": "20995393", "title": "Personal experiences in the two wars.", "content": "Personal experiences in the two wars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995393"}
{"pmid": "20995394", "title": "From the diary of a consultant in Italy.", "content": "From the diary of a consultant in Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995394"}
{"pmid": "20995395", "title": "Cachexia of obscure origin.", "content": "Cachexia of obscure origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995395"}
{"pmid": "20995397", "title": "Odd aids to general practice.", "content": "Odd aids to general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995397"}
{"pmid": "20995396", "title": "Confinements at home or in hospital.", "content": "Confinements at home or in hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995396"}
{"pmid": "20995398", "title": "The results of lumbar sympathectomy for arteriosclerosis of the lower limbs.", "content": "The results of lumbar sympathectomy for arteriosclerosis of the lower limbs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995398"}
{"pmid": "20995399", "title": "Mitral stenosis and silicosis.", "content": "Mitral stenosis and silicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995399"}
{"pmid": "20995400", "title": "An outline of gingivectomy.", "content": "An outline of gingivectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995400"}
{"pmid": "20995401", "title": "Plexiform neuroma; with a general discussion on Von Recklinghausen's disease.", "content": "Plexiform neuroma; with a general discussion on Von Recklinghausen's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995401"}
{"pmid": "20995402", "title": "The life and works of Dr. W. S. Kirkes [1823-1864].", "content": "The life and works of Dr. W. S. Kirkes [1823-1864].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995402"}
{"pmid": "20995421", "title": "Surgery of war injuries of the eyelids.", "content": "Surgery of war injuries of the eyelids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995421"}
{"pmid": "20995422", "title": "A simple aid in difficult abdominal closures.", "content": "A simple aid in difficult abdominal closures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995422"}
{"pmid": "20995423", "title": "Guide for nailing fractures of the femoral neck.", "content": "Guide for nailing fractures of the femoral neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995423"}
{"pmid": "20995424", "title": "Heart complications in infectious mononucleosis; report of a case.", "content": "Heart complications in infectious mononucleosis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995424"}
{"pmid": "20995425", "title": "Primary atypical pneumonia.", "content": "Primary atypical pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995425"}
{"pmid": "20995426", "title": "Spinal fluid protein in the retrospective diagnosis of subclinical poliomyelitis.", "content": "Spinal fluid protein in the retrospective diagnosis of subclinical poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995426"}
{"pmid": "20995428", "title": "Effect of topical penicillin on infections of the upper respiratory tract.", "content": "Effect of topical penicillin on infections of the upper respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995428"}
{"pmid": "20995427", "title": "The treatment of early syphilis with penicillin.", "content": "The treatment of early syphilis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995427"}
{"pmid": "20995429", "title": "Delay in diagnosing malaria after sulfadiazine therapy; two case reports.", "content": "Delay in diagnosing malaria after sulfadiazine therapy; two case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995429"}
{"pmid": "20995431", "title": "The management of diabetes mellitus during pregnancy.", "content": "The management of diabetes mellitus during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995431"}
{"pmid": "20995430", "title": "Hydrogen ion concentration (pH) of Monilia albicans infection and treatment.", "content": "Hydrogen ion concentration (pH) of Monilia albicans infection and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995430"}
{"pmid": "20995433", "title": "Results of removal of ruptured intervertebral discs and combined disc-fusion operations; an analysis of 288 operations.", "content": "Results of removal of ruptured intervertebral discs and combined disc-fusion operations; an analysis of 288 operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995433"}
{"pmid": "20995432", "title": "Physical therapy in a general practice.", "content": "Physical therapy in a general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995432"}
{"pmid": "20995452", "title": "The place of penicillin in the treatment of syphilis.", "content": "The place of penicillin in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995452"}
{"pmid": "20995453", "title": "The evolution of the art of medicine.", "content": "The evolution of the art of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995453"}
{"pmid": "20995454", "title": "The abnormal physiology of congestive heart failure.", "content": "The abnormal physiology of congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995454"}
{"pmid": "20995455", "title": "The pattern of injuries produced by the atomic bombs at Hiroshima and Nagasaki.", "content": "The pattern of injuries produced by the atomic bombs at Hiroshima and Nagasaki.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995455"}
{"pmid": "20995456", "title": "Diagnosis and treatment of localized infections in the hand.", "content": "Diagnosis and treatment of localized infections in the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995456"}
{"pmid": "20995457", "title": "The role of the psychiatrist in the naval disciplinary barracks.", "content": "The role of the psychiatrist in the naval disciplinary barracks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995457"}
{"pmid": "20995458", "title": "Condition simulating appendicitis following cholera vaccine inoculation.", "content": "Condition simulating appendicitis following cholera vaccine inoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995458"}
{"pmid": "20995459", "title": "Eye injuries in amphibious warfare.", "content": "Eye injuries in amphibious warfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995459"}
{"pmid": "20995460", "title": "X-ray darkroom training as an adjunct to the rehabilitation of the blind.", "content": "X-ray darkroom training as an adjunct to the rehabilitation of the blind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995460"}
{"pmid": "20995461", "title": "A mobile surgical unit in a combat area.", "content": "A mobile surgical unit in a combat area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995461"}
{"pmid": "20995462", "title": "Isolation and identification of enteric pathogens at a naval base in North Africa.", "content": "Isolation and identification of enteric pathogens at a naval base in North Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995462"}
{"pmid": "20995463", "title": "The value of the social service history in the detection of those psychiatrically unsuited for military service.", "content": "The value of the social service history in the detection of those psychiatrically unsuited for military service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995463"}
{"pmid": "20995464", "title": "The cancer problem in the Navy.", "content": "The cancer problem in the Navy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995464"}
{"pmid": "20995465", "title": "Sulfadiazine and penicillin in the treatment of scarlet fever.", "content": "Sulfadiazine and penicillin in the treatment of scarlet fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995465"}
{"pmid": "20995466", "title": "Penicillin-sterile empyema.", "content": "Penicillin-sterile empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995466"}
{"pmid": "20995467", "title": "Treatment of impetigo at a tropical base.", "content": "Treatment of impetigo at a tropical base.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995467"}
{"pmid": "20995468", "title": "Pilot-staleness.", "content": "Pilot-staleness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995468"}
{"pmid": "20995469", "title": "Surgical technique for facial lacerations.", "content": "Surgical technique for facial lacerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995469"}
{"pmid": "20995470", "title": "Notes on biopsy with special reference to its use and misuse.", "content": "Notes on biopsy with special reference to its use and misuse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995470"}
{"pmid": "20995471", "title": "Bone felon.", "content": "Bone felon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995471"}
{"pmid": "20995472", "title": "Stevens and Johnson's disease.", "content": "Stevens and Johnson's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995472"}
{"pmid": "20995473", "title": "Orbital hemorrhages following pressure on neck.", "content": "Orbital hemorrhages following pressure on neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995473"}
{"pmid": "20995474", "title": "Huntington's chorea.", "content": "Huntington's chorea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995474"}
{"pmid": "20995475", "title": "Acute appendicitis treated with penicillin.", "content": "Acute appendicitis treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995475"}
{"pmid": "20995476", "title": "Photofluorographic examinations of the chest of all Navy and Marine Corps personnel, 1944-1945.", "content": "Photofluorographic examinations of the chest of all Navy and Marine Corps personnel, 1944-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995476"}
{"pmid": "20995477", "title": "Typhus in Egypt during World War II.", "content": "Typhus in Egypt during World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995477"}
{"pmid": "20995478", "title": "ANNUAL report of the Surgeon General, U.S. Navy concerning statistics of diseases and injuries in the United States Navy for the calendar year 1942. Washington, 1945.", "content": "ANNUAL report of the Surgeon General, U.S. Navy concerning statistics of diseases and injuries in the United States Navy for the calendar year 1942. Washington, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995478"}
{"pmid": "20995480", "title": "Solar and sidereal diurnal variations of cosmic rays.", "content": "Solar and sidereal diurnal variations of cosmic rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995480"}
{"pmid": "20995481", "title": "Radioactivity of samarium.", "content": "Radioactivity of samarium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995481"}
{"pmid": "20995482", "title": "A zonally corrected electron lens.", "content": "A zonally corrected electron lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995482"}
{"pmid": "20995483", "title": "X-ray fibre pattern of part of a single starch grain; powder photographs on potato, wheat and arrowroot (Maranta) starch.", "content": "X-ray fibre pattern of part of a single starch grain; powder photographs on potato, wheat and arrowroot (Maranta) starch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995483"}
{"pmid": "20995484", "title": "Photosynthesis, philosophy and Priestley.", "content": "Photosynthesis, philosophy and Priestley.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995484"}
{"pmid": "20995485", "title": "Isolation of the growth-promoting factor present in the fatty acids of summer-butter.", "content": "Isolation of the growth-promoting factor present in the fatty acids of summer-butter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995485"}
{"pmid": "20995486", "title": "Histological demonstration of mucin after periodic acid.", "content": "Histological demonstration of mucin after periodic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995486"}
{"pmid": "20995487", "title": "Cancer research in the United States.", "content": "Cancer research in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995487"}
{"pmid": "20995488", "title": "POLYMERS and polymerization.", "content": "POLYMERS and polymerization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995488"}
{"pmid": "20995489", "title": "Preis, 1846-1916.", "content": "Preis, 1846-1916.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995489"}
{"pmid": "20995490", "title": "Fluctuations in cosmic radiation at radio-frequencies.", "content": "Fluctuations in cosmic radiation at radio-frequencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995490"}
{"pmid": "20995491", "title": "Investigations of near infra-red radiations by means of image converters.", "content": "Investigations of near infra-red radiations by means of image converters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995491"}
{"pmid": "20995492", "title": "A new human blood group antigen of frequent occurrence.", "content": "A new human blood group antigen of frequent occurrence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995492"}
{"pmid": "20995493", "title": "Combined action upon muscle of adenosine triphosphate, acetylcholine and potassium, calcium and magnesium ions.", "content": "Combined action upon muscle of adenosine triphosphate, acetylcholine and potassium, calcium and magnesium ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995493"}
{"pmid": "20995494", "title": "Cyclic variations of the submicroscopic structure of the cortical layer of fertilized and parthenogenetic sea urchin eggs.", "content": "Cyclic variations of the submicroscopic structure of the cortical layer of fertilized and parthenogenetic sea urchin eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995494"}
{"pmid": "20995495", "title": "Relations between the source of nitrogen and antibiotic formation by Aspergillus fumigatus, Fresenius.", "content": "Relations between the source of nitrogen and antibiotic formation by Aspergillus fumigatus, Fresenius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995495"}
{"pmid": "20995496", "title": "Penicillin treatment of syphilis.", "content": "Penicillin treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995496"}
{"pmid": "20995497", "title": "The conversion of carotene into vitamin A.", "content": "The conversion of carotene into vitamin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995497"}
{"pmid": "20995498", "title": "Effect of x-rays on the rate of turnover of phosphatides.", "content": "Effect of x-rays on the rate of turnover of phosphatides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995498"}
{"pmid": "20995499", "title": "Demonstration of phosphatase in decalcified bone.", "content": "Demonstration of phosphatase in decalcified bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995499"}
{"pmid": "20995500", "title": "Application of the paper partition chromatogram to the qualitative analysis of reducing sugars.", "content": "Application of the paper partition chromatogram to the qualitative analysis of reducing sugars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995500"}
{"pmid": "20995501", "title": "Alginic acid-acetate.", "content": "Alginic acid-acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995501"}
{"pmid": "20995502", "title": "Ageing in man and other animals.", "content": "Ageing in man and other animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995502"}
{"pmid": "20995503", "title": "Mimetic polymorphism.", "content": "Mimetic polymorphism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995503"}
{"pmid": "20995504", "title": "Research in the social sciences.", "content": "Research in the social sciences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995504"}
{"pmid": "20995505", "title": "Mechanism of spontaneous cure in puberty of ringworm of the scalp.", "content": "Mechanism of spontaneous cure in puberty of ringworm of the scalp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995505"}
{"pmid": "20995506", "title": "Inhibition of the catalyzed thermal decomposition of DDT.", "content": "Inhibition of the catalyzed thermal decomposition of DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995506"}
{"pmid": "20995507", "title": "Effect of streptomycin on budwood infected with Phytomonas pruni.", "content": "Effect of streptomycin on budwood infected with Phytomonas pruni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995507"}
{"pmid": "20995508", "title": "On the term normality factor.", "content": "On the term normality factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995508"}
{"pmid": "20995509", "title": "Rediscovery in the vitamin C field.", "content": "Rediscovery in the vitamin C field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995509"}
{"pmid": "20995510", "title": "The occurrence of crystalline naringin on grapefruit rind.", "content": "The occurrence of crystalline naringin on grapefruit rind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995510"}
{"pmid": "20995511", "title": "Effect of some sulfhydryl-containing substances on the toxicity of an organic mercurial compound.", "content": "Effect of some sulfhydryl-containing substances on the toxicity of an organic mercurial compound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995511"}
{"pmid": "20995512", "title": "The mechanism of myotonic contraction.", "content": "The mechanism of myotonic contraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995512"}
{"pmid": "20995513", "title": "Biological incorporation of a choline homologue into liver phospholipids.", "content": "Biological incorporation of a choline homologue into liver phospholipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995513"}
{"pmid": "20995514", "title": "The effect of alloxan on the in vitro formation of glucose by the liver.", "content": "The effect of alloxan on the in vitro formation of glucose by the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995514"}
{"pmid": "20995515", "title": "Agar technique for arresting movement in Protozoa.", "content": "Agar technique for arresting movement in Protozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995515"}
{"pmid": "20995516", "title": "A spectrophotometric method for the determination of p,p'-DDT.", "content": "A spectrophotometric method for the determination of p,p'-DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995516"}
{"pmid": "20995517", "title": "The ascorbic acid content of some Malpighia fruits and jellies.", "content": "The ascorbic acid content of some Malpighia fruits and jellies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995517"}
{"pmid": "20995518", "title": "Notes on the results of Army intelligence testing in World War I.", "content": "Notes on the results of Army intelligence testing in World War I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995518"}
{"pmid": "20995519", "title": "Embryonic induction in regenerating mesenchyme.", "content": "Embryonic induction in regenerating mesenchyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995519"}
{"pmid": "20995521", "title": "Atomic energy.", "content": "Atomic energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995521"}
{"pmid": "20995520", "title": "Mustard gas mutations in Neurospora.", "content": "Mustard gas mutations in Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995520"}
{"pmid": "20995522", "title": "The variation in reproductive capacity of plants.", "content": "The variation in reproductive capacity of plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995522"}
{"pmid": "20995524", "title": "Some aspects of the geology of water supply.", "content": "Some aspects of the geology of water supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995524"}
{"pmid": "20995523", "title": "Physical states of aggregation.", "content": "Physical states of aggregation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995523"}
{"pmid": "20995525", "title": "Our first astronomer royal; the tercentenary of John Flamsteed.", "content": "Our first astronomer royal; the tercentenary of John Flamsteed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995525"}
{"pmid": "20995526", "title": "The Walden inversion.", "content": "The Walden inversion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995526"}
{"pmid": "20995527", "title": "The new optical glasses.", "content": "The new optical glasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995527"}
{"pmid": "20995529", "title": "Biochemistry.", "content": "Biochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995529"}
{"pmid": "20995528", "title": "Mimicry, protective resemblance and animal behaviour.", "content": "Mimicry, protective resemblance and animal behaviour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995528"}
{"pmid": "20995530", "title": "Zoology.", "content": "Zoology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995530"}
{"pmid": "20995531", "title": "Entomology.", "content": "Entomology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995531"}
{"pmid": "20995532", "title": "Course and rate of regeneration of motor fibers following lesions of the radial nerve.", "content": "Course and rate of regeneration of motor fibers following lesions of the radial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995532"}
{"pmid": "20995533", "title": "Electric shock therapy of elderly patients.", "content": "Electric shock therapy of elderly patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995533"}
{"pmid": "20995534", "title": "Pattern of metabolic depression induced with pentothal sodium.", "content": "Pattern of metabolic depression induced with pentothal sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995534"}
{"pmid": "20995535", "title": "Effects of antibiotic substances on the central nervous system.", "content": "Effects of antibiotic substances on the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995535"}
{"pmid": "20995536", "title": "Abnormal delay of visual perception.", "content": "Abnormal delay of visual perception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995536"}
{"pmid": "20995537", "title": "Dominant brain wave frequencies as measures of physicochemical processes in cerebral cortex.", "content": "Dominant brain wave frequencies as measures of physicochemical processes in cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995537"}
{"pmid": "20995538", "title": "Is restoration of inhibited conditioned reactions by insulin coma specific for Pavlovian inhibitions? Contribution to the theory of shock treatment.", "content": "Is restoration of inhibited conditioned reactions by insulin coma specific for Pavlovian inhibitions? Contribution to the theory of shock treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995538"}
{"pmid": "20995539", "title": "A power factor in general intelligence; effects of lesions of the brain.", "content": "A power factor in general intelligence; effects of lesions of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995539"}
{"pmid": "20995540", "title": "Group therapy in an extramural clinic.", "content": "Group therapy in an extramural clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995540"}
{"pmid": "20995541", "title": "Diastematomyelia.", "content": "Diastematomyelia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995541"}
{"pmid": "20995542", "title": "Connections of the cingulum.", "content": "Connections of the cingulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995542"}
{"pmid": "20995543", "title": "The mesodermal tissue in nerve lesions and repair.", "content": "The mesodermal tissue in nerve lesions and repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995543"}
{"pmid": "20995545", "title": "The prevention of maladjustment in an Army Service Forces Training Center.", "content": "The prevention of maladjustment in an Army Service Forces Training Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995545"}
{"pmid": "20995544", "title": "Friedreich's ataxia (a familial herditary study of three cases).", "content": "Friedreich's ataxia (a familial herditary study of three cases).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995544"}
{"pmid": "20995546", "title": "Plan of organization of an industrial health program.", "content": "Plan of organization of an industrial health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995546"}
{"pmid": "20995547", "title": "A near fatality from curare preceding electro-shock therapy.", "content": "A near fatality from curare preceding electro-shock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995547"}
{"pmid": "20995548", "title": "Hypertensive brain disease.", "content": "Hypertensive brain disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995548"}
{"pmid": "20995549", "title": "Control of grand mal epilepsy with electro-shock.", "content": "Control of grand mal epilepsy with electro-shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995549"}
{"pmid": "20995550", "title": "A comparison of social attitudes among American and German youth.", "content": "A comparison of social attitudes among American and German youth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995550"}
{"pmid": "20995553", "title": "CASE reports; letters from Jenny.", "content": "CASE reports; letters from Jenny.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995553"}
{"pmid": "20995551", "title": "Forming impressions of personality.", "content": "Forming impressions of personality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995551"}
{"pmid": "20995552", "title": "Performance of brain-damaged cases on a memory-for-designs test.", "content": "Performance of brain-damaged cases on a memory-for-designs test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995552"}
{"pmid": "20995554", "title": "Cultural-chronological strata in speech.", "content": "Cultural-chronological strata in speech.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995554"}
{"pmid": "20995555", "title": "Basic personality structure and the subgroup.", "content": "Basic personality structure and the subgroup.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995555"}
{"pmid": "20995556", "title": "Paroxysmal slow waves in the electroencephalograms of patients with epilepsy and with subcortical lesions.", "content": "Paroxysmal slow waves in the electroencephalograms of patients with epilepsy and with subcortical lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995556"}
{"pmid": "20995557", "title": "Lückenschädel in a patient with amnesia amenable to hypnotherapy: a personality study.", "content": "Lückenschädel in a patient with amnesia amenable to hypnotherapy: a personality study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995557"}
{"pmid": "20995559", "title": "Classification of types of behavior noted in general prisoners.", "content": "Classification of types of behavior noted in general prisoners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995559"}
{"pmid": "20995558", "title": "Preliminary report on the effect of glutamic acid administration in mentally retarded subjects.", "content": "Preliminary report on the effect of glutamic acid administration in mentally retarded subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995558"}
{"pmid": "20995560", "title": "Problems of military neuropsychiatry.", "content": "Problems of military neuropsychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995560"}
{"pmid": "20995562", "title": "The concept of induced insanity in family units.", "content": "The concept of induced insanity in family units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995562"}
{"pmid": "20995561", "title": "Electroshock and personality structure.", "content": "Electroshock and personality structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995561"}
{"pmid": "20995563", "title": "Bilateral and multiple ruptured discs as one cause of persistent symptoms following operation for a herniated disc.", "content": "Bilateral and multiple ruptured discs as one cause of persistent symptoms following operation for a herniated disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995563"}
{"pmid": "20995564", "title": "The results of hospital treatment, including electric shock of psychoneurotic patients.", "content": "The results of hospital treatment, including electric shock of psychoneurotic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995564"}
{"pmid": "20995565", "title": "Results of treatment of psychoneuroses by the general practitioner; a follow-up study of 500 cases.", "content": "Results of treatment of psychoneuroses by the general practitioner; a follow-up study of 500 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995565"}
{"pmid": "20995573", "title": "Migraine; etiology and treatment of the sick headache.", "content": "Migraine; etiology and treatment of the sick headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995573"}
{"pmid": "20995574", "title": "America looks at nursing.", "content": "America looks at nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995574"}
{"pmid": "20995575", "title": "The public health nurse on the hospital staff.", "content": "The public health nurse on the hospital staff.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995575"}
{"pmid": "20995566", "title": "Studies on headache; mechanisms of chronic post-traumatic headache.", "content": "Studies on headache; mechanisms of chronic post-traumatic headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995566"}
{"pmid": "20995576", "title": "Nursing in prepayment medical care plans.", "content": "Nursing in prepayment medical care plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995576"}
{"pmid": "20995567", "title": "A new psychiatric rating scale.", "content": "A new psychiatric rating scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995567"}
{"pmid": "20995577", "title": "Progress toward security for nurses.", "content": "Progress toward security for nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995577"}
{"pmid": "20995578", "title": "Diet and insulin in the care of the diabetic patient.", "content": "Diet and insulin in the care of the diabetic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995578"}
{"pmid": "20995579", "title": "The nurse and the diabetic patient.", "content": "The nurse and the diabetic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995579"}
{"pmid": "20995580", "title": "The philosophical aspects of cost accounting in nursing schools.", "content": "The philosophical aspects of cost accounting in nursing schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995580"}
{"pmid": "20995569", "title": "The concept of disease.", "content": "The concept of disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995569"}
{"pmid": "20995581", "title": "Haemoglobin estimations.", "content": "Haemoglobin estimations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995581"}
{"pmid": "20995568", "title": "Changes in the electroencephalogram and in the excretion of 17-ketosteroids accompanying electroshock therapy of agitated depression.", "content": "Changes in the electroencephalogram and in the excretion of 17-ketosteroids accompanying electroshock therapy of agitated depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995568"}
{"pmid": "20995582", "title": "DIPHTHERIA immunisation campaign.", "content": "DIPHTHERIA immunisation campaign.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995582"}
{"pmid": "20995570", "title": "Analysis of neuroses developing after combat in four individuals with outstanding combat records.", "content": "Analysis of neuroses developing after combat in four individuals with outstanding combat records.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995570"}
{"pmid": "20995572", "title": "The psychosomatic factors in ulcerative colitis.", "content": "The psychosomatic factors in ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995572"}
{"pmid": "20995571", "title": "Psychogenic peripheral vasospasm.", "content": "Psychogenic peripheral vasospasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995571"}
{"pmid": "20995587", "title": "Psychiatric treatment.", "content": "Psychiatric treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995587"}
{"pmid": "20995588", "title": "Fijian infant welfare; an outline of its history and organisation.", "content": "Fijian infant welfare; an outline of its history and organisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995588"}
{"pmid": "20995589", "title": "Social welfare in New Zealand.", "content": "Social welfare in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995589"}
{"pmid": "20995590", "title": "Hospital cleaning by outside contract.", "content": "Hospital cleaning by outside contract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995590"}
{"pmid": "20995591", "title": "Bone tuberculosis.", "content": "Bone tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995591"}
{"pmid": "20995592", "title": "SUGGESTED nursing technique for infectious diseases (including tuberculosis) in hospitals.", "content": "SUGGESTED nursing technique for infectious diseases (including tuberculosis) in hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995592"}
{"pmid": "20995593", "title": "Maintaining health under rationing.", "content": "Maintaining health under rationing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995593"}
{"pmid": "20995594", "title": "Some aspects of physiological midwifery.", "content": "Some aspects of physiological midwifery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995594"}
{"pmid": "20995595", "title": "Cancer, general pathology and principles of treatment.", "content": "Cancer, general pathology and principles of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995595"}
{"pmid": "20995596", "title": "An adequate supply of milk of good quality for human consumption.", "content": "An adequate supply of milk of good quality for human consumption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995596"}
{"pmid": "20995597", "title": "Psychiatry in the general practice of medicine.", "content": "Psychiatry in the general practice of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995597"}
{"pmid": "20995598", "title": "Plunket nursing.", "content": "Plunket nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995598"}
{"pmid": "20995599", "title": "Experimental investigation of cyclofusion.", "content": "Experimental investigation of cyclofusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995599"}
{"pmid": "20995600", "title": "Productive industrial visual efficiency.", "content": "Productive industrial visual efficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995600"}
{"pmid": "20995601", "title": "SHEARD Foundation for Education and Research in Vision.", "content": "SHEARD Foundation for Education and Research in Vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995601"}
{"pmid": "20995603", "title": "Near infra-red transmitting filters.", "content": "Near infra-red transmitting filters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995603"}
{"pmid": "20995602", "title": "Spectroscopy, past, present, and future.", "content": "Spectroscopy, past, present, and future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995602"}
{"pmid": "20995604", "title": "On two accessories of three-dimensional colorimentry; the probable error of colorimetric tensor components as derived from a number of color matchings.", "content": "On two accessories of three-dimensional colorimentry; the probable error of colorimetric tensor components as derived from a number of color matchings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995604"}
{"pmid": "20995605", "title": "On two accessories of three-dimensional colorimetry; the determination of the principal colorimetric axes at any point of the color threefold.", "content": "On two accessories of three-dimensional colorimetry; the determination of the principal colorimetric axes at any point of the color threefold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995605"}
{"pmid": "20995606", "title": "The basic sensation curves of the three-color theory.", "content": "The basic sensation curves of the three-color theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995606"}
{"pmid": "20995607", "title": "A plan to eradicate the common cold.", "content": "A plan to eradicate the common cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995607"}
{"pmid": "20995608", "title": "Incidence and significance of infected tonsil remnants.", "content": "Incidence and significance of infected tonsil remnants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995608"}
{"pmid": "20995609", "title": "The use of the Berman locator in removal of intra-ocular foreign bodies.", "content": "The use of the Berman locator in removal of intra-ocular foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995609"}
{"pmid": "20995610", "title": "Retinoscopy simplified.", "content": "Retinoscopy simplified.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995610"}
{"pmid": "20995611", "title": "Instillation penicillin therapy in ophthalmology.", "content": "Instillation penicillin therapy in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995611"}
{"pmid": "20995612", "title": "Rhinology in children, resume of and comments on the literature for 1945.", "content": "Rhinology in children, resume of and comments on the literature for 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995612"}
{"pmid": "20995613", "title": "In ventor of the laryngoscope; Benjamin Guy Babington.", "content": "In ventor of the laryngoscope; Benjamin Guy Babington.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995613"}
{"pmid": "20995615", "title": "Anti-fogging device, air jet; for use on laryngoscopes, bronchoscopes, mouth gags, etc.", "content": "Anti-fogging device, air jet; for use on laryngoscopes, bronchoscopes, mouth gags, etc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995615"}
{"pmid": "20995617", "title": "Liver function tests.", "content": "Liver function tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995617"}
{"pmid": "20995616", "title": "Relation of urea nitrogen of the blood; antemortem data on whole blood.", "content": "Relation of urea nitrogen of the blood; antemortem data on whole blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995616"}
{"pmid": "20995614", "title": "Round shadows in the maxillary sinuses.", "content": "Round shadows in the maxillary sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995614"}
{"pmid": "20995618", "title": "Simplified test for fragility of erythrocytes.", "content": "Simplified test for fragility of erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995618"}
{"pmid": "20995619", "title": "Composition of Seitz filter pads.", "content": "Composition of Seitz filter pads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995619"}
{"pmid": "20995620", "title": "Microtechnic of the pathologic eye; orientation and division of the eyeball.", "content": "Microtechnic of the pathologic eye; orientation and division of the eyeball.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995620"}
{"pmid": "20995622", "title": "Arteriovenous fistula involving aorta and superior vena cava.", "content": "Arteriovenous fistula involving aorta and superior vena cava.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995622"}
{"pmid": "20995621", "title": "Blood cell counts and hemoglobin value in normal and diabetic dogs.", "content": "Blood cell counts and hemoglobin value in normal and diabetic dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995621"}
{"pmid": "20995623", "title": "Sacral spina bifida, intrapelvic meningocele, and sacrococcygeal teratoma.", "content": "Sacral spina bifida, intrapelvic meningocele, and sacrococcygeal teratoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995623"}
{"pmid": "20995624", "title": "Staining of chromaffin tissue.", "content": "Staining of chromaffin tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995624"}
{"pmid": "20995625", "title": "Nomogram for calculating serum total base.", "content": "Nomogram for calculating serum total base.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995625"}
{"pmid": "20995626", "title": "A nomogram for photometric determinations.", "content": "A nomogram for photometric determinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995626"}
{"pmid": "20995627", "title": "Use of sodium azide in isolation of gram-positive cocci.", "content": "Use of sodium azide in isolation of gram-positive cocci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995627"}
{"pmid": "20995628", "title": "Micro cephalin-cholesterol flocculation test on blood from finger.", "content": "Micro cephalin-cholesterol flocculation test on blood from finger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995628"}
{"pmid": "20995629", "title": "Apparatus for determination of specific gravity of multiple specimens of urine.", "content": "Apparatus for determination of specific gravity of multiple specimens of urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995629"}
{"pmid": "20995630", "title": "Spectrophotometric method for determination of hemoglobin.", "content": "Spectrophotometric method for determination of hemoglobin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995630"}
{"pmid": "20995631", "title": "Tumor of tactile end organs.", "content": "Tumor of tactile end organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995631"}
{"pmid": "20995632", "title": "Pathologic aspects of atmospheric blast injuries in man.", "content": "Pathologic aspects of atmospheric blast injuries in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995632"}
{"pmid": "20995633", "title": "Structure of the testis in infancy and in childhood; with a discussion of the so-called underdeveloped testis.", "content": "Structure of the testis in infancy and in childhood; with a discussion of the so-called underdeveloped testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995633"}
{"pmid": "20995635", "title": "Angiomatoid formations in the genital organs with and without tumor formation.", "content": "Angiomatoid formations in the genital organs with and without tumor formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995635"}
{"pmid": "20995634", "title": "Renal changes associated with a chloride-deficient diet in the rat.", "content": "Renal changes associated with a chloride-deficient diet in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995634"}
{"pmid": "20995636", "title": "Hepar lobatum; clinical significance of the anatomic changes.", "content": "Hepar lobatum; clinical significance of the anatomic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995636"}
{"pmid": "20995637", "title": "Birefringence in tissues.", "content": "Birefringence in tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995637"}
{"pmid": "20995638", "title": "Experimental atherosclerosis; the effect of prolonged feeding of egg yolk powder in rats.", "content": "Experimental atherosclerosis; the effect of prolonged feeding of egg yolk powder in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995638"}
{"pmid": "20995639", "title": "Tumor of the thoracic inlet producing the Pancoast syndrome; a report of 17 cases and a review of the literature.", "content": "Tumor of the thoracic inlet producing the Pancoast syndrome; a report of 17 cases and a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995639"}
{"pmid": "20995640", "title": "Stem cell lymphoma of the newborn.", "content": "Stem cell lymphoma of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995640"}
{"pmid": "20995641", "title": "Comparison of the tumours produced by 2-acetyl-amino-fluorene in piebald and Wistar rats.", "content": "Comparison of the tumours produced by 2-acetyl-amino-fluorene in piebald and Wistar rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995641"}
{"pmid": "20995642", "title": "Investigation into the production of bacteriostatic substances by fungi; preliminary examination of the fifth 100 species, all basidiomycetes, mostly of the wood-destroying type.", "content": "Investigation into the production of bacteriostatic substances by fungi; preliminary examination of the fifth 100 species, all basidiomycetes, mostly of the wood-destroying type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995642"}
{"pmid": "20995643", "title": "Shope papilloma and sheep dermatitis in the rabbit; mutual interference, superinfection, and effects of chemical pre-treatment of the skin.", "content": "Shope papilloma and sheep dermatitis in the rabbit; mutual interference, superinfection, and effects of chemical pre-treatment of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995643"}
{"pmid": "20995644", "title": "The effect of feeding carcinogenic hydrocarbons dissolved in aqueous soap solution on the stomach of CBA mice.", "content": "The effect of feeding carcinogenic hydrocarbons dissolved in aqueous soap solution on the stomach of CBA mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995644"}
{"pmid": "20995645", "title": "Renal effects of protein-deficient vegetable diets; a functional and histological study.", "content": "Renal effects of protein-deficient vegetable diets; a functional and histological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995645"}
{"pmid": "20995647", "title": "The influence of methylation on carcinogenic activity; N-methyl-3 : 4 : 5 : 6-dibenzcarbazole.", "content": "The influence of methylation on carcinogenic activity; N-methyl-3 : 4 : 5 : 6-dibenzcarbazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995647"}
{"pmid": "20995646", "title": "Observations on the acidophil cell changes in the pituitary in thyroxine deficiency states; acidophil degranulation in relation to goitrogenic agents and extrathyroidal thyroxine synthesis.", "content": "Observations on the acidophil cell changes in the pituitary in thyroxine deficiency states; acidophil degranulation in relation to goitrogenic agents and extrathyroidal thyroxine synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995646"}
{"pmid": "20995649", "title": "Some observations on the blood-clotting mechanism; the role of fibrinogen and platelets, with reference to a case of congenital afibrinogenaemia.", "content": "Some observations on the blood-clotting mechanism; the role of fibrinogen and platelets, with reference to a case of congenital afibrinogenaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995649"}
{"pmid": "20995648", "title": "Faecal urobilinogen; clinical evaluation of a simplified method of estimation.", "content": "Faecal urobilinogen; clinical evaluation of a simplified method of estimation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995648"}
{"pmid": "20995658", "title": "Hospital victory.", "content": "Hospital victory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995658"}
{"pmid": "20995659", "title": "Blueprint for rehabilitation.", "content": "Blueprint for rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995659"}
{"pmid": "20995660", "title": "The pharmacy of penicillin.", "content": "The pharmacy of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995660"}
{"pmid": "20995663", "title": "HIPERTENSION.", "content": "HIPERTENSION.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995663"}
{"pmid": "20995664", "title": "Redoxon Roche.", "content": "Redoxon Roche.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995664"}
{"pmid": "20995667", "title": "FOOD for thought; vitamin B and mental activity.", "content": "FOOD for thought; vitamin B and mental activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995667"}
{"pmid": "20995668", "title": "LOCAL injection of penicillin.", "content": "LOCAL injection of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995668"}
{"pmid": "20995669", "title": "POOR man's Friedman test.", "content": "POOR man's Friedman test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995669"}
{"pmid": "20995670", "title": "ESTROGEN: vitamin B complex; cancer.", "content": "ESTROGEN: vitamin B complex; cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995670"}
{"pmid": "20995671", "title": "DISCOVERY of tridione.", "content": "DISCOVERY of tridione.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995671"}
{"pmid": "20995677", "title": "An unknown autobiographical fragment by Freud.", "content": "An unknown autobiographical fragment by Freud.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995677"}
{"pmid": "20995678", "title": "The legend of the unfathomable waters.", "content": "The legend of the unfathomable waters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995678"}
{"pmid": "20995679", "title": "The mother in the religious concepts of Judaism.", "content": "The mother in the religious concepts of Judaism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995679"}
{"pmid": "20995680", "title": "The effect of alcohol on the personality inventory.", "content": "The effect of alcohol on the personality inventory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995680"}
{"pmid": "20995681", "title": "Psychobiological screening procedures in the War Shipping Administration.", "content": "Psychobiological screening procedures in the War Shipping Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995681"}
{"pmid": "20995673", "title": "ESTROGEN and habitual abortion; a reversal of opinion on their relationship.", "content": "ESTROGEN and habitual abortion; a reversal of opinion on their relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995673"}
{"pmid": "20995672", "title": "STREPTOMYCIN; a brief review of recent applications.", "content": "STREPTOMYCIN; a brief review of recent applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995672"}
{"pmid": "20995682", "title": "The Cornell Indices and the Cornell Word Form; construction and standardization.", "content": "The Cornell Indices and the Cornell Word Form; construction and standardization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995682"}
{"pmid": "20995683", "title": "The Cornell Indices and the Cornell Word Form; results.", "content": "The Cornell Indices and the Cornell Word Form; results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995683"}
{"pmid": "20995684", "title": "The Cornell Indices and the Cornell Word Form; application.", "content": "The Cornell Indices and the Cornell Word Form; application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995684"}
{"pmid": "20995674", "title": "PENICILLIN and syphilis.", "content": "PENICILLIN and syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995674"}
{"pmid": "20995685", "title": "The Cornell Selectee Index; an aid in psychiatric diagnosis.", "content": "The Cornell Selectee Index; an aid in psychiatric diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995685"}
{"pmid": "20995687", "title": "Personality and diagnostic evaluation by means of non-projective techniques.", "content": "Personality and diagnostic evaluation by means of non-projective techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995687"}
{"pmid": "20995686", "title": "The expression of personality and maladjustment in intelligence test results.", "content": "The expression of personality and maladjustment in intelligence test results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995686"}
{"pmid": "20995688", "title": "Difference between cases giving valid and invalid personality inventory responses.", "content": "Difference between cases giving valid and invalid personality inventory responses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995688"}
{"pmid": "20995690", "title": "Problems of performance analysis in the study of personality.", "content": "Problems of performance analysis in the study of personality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995690"}
{"pmid": "20995689", "title": "Principles underlying nonprojective tests of personality.", "content": "Principles underlying nonprojective tests of personality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995689"}
{"pmid": "20995676", "title": "SOME pathological conditions of the eye.", "content": "SOME pathological conditions of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995676"}
{"pmid": "20995696", "title": "The effect of illumination on reading rate and comprehension of college students.", "content": "The effect of illumination on reading rate and comprehension of college students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995696"}
{"pmid": "20995698", "title": "Success and failure in serial learning; isolation and the Thorndike effect.", "content": "Success and failure in serial learning; isolation and the Thorndike effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995698"}
{"pmid": "20995697", "title": "Meaningful similarity and interference in learning.", "content": "Meaningful similarity and interference in learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995697"}
{"pmid": "20995699", "title": "Rehearsal and guessing habits as sources of the spread of effect.", "content": "Rehearsal and guessing habits as sources of the spread of effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995699"}
{"pmid": "20995700", "title": "The ability to judge pitch.", "content": "The ability to judge pitch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995700"}
{"pmid": "20995701", "title": "The rate of learning measured at a single synapse.", "content": "The rate of learning measured at a single synapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995701"}
{"pmid": "20995694", "title": "Time study and the fundamental nature of manual skill.", "content": "Time study and the fundamental nature of manual skill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995694"}
{"pmid": "20995702", "title": "Level of autonomic activity and electroencephalogram.", "content": "Level of autonomic activity and electroencephalogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995702"}
{"pmid": "20995703", "title": "A method for the maintenance of chronic spinal animals.", "content": "A method for the maintenance of chronic spinal animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995703"}
{"pmid": "20995693", "title": "A short method of scoring the Minnesota Multiphasic Personality Inventory.", "content": "A short method of scoring the Minnesota Multiphasic Personality Inventory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995693"}
{"pmid": "20995704", "title": "The bentonite electrode.", "content": "The bentonite electrode.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995704"}
{"pmid": "20995705", "title": "Relation between government and the status of women.", "content": "Relation between government and the status of women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995705"}
{"pmid": "20995691", "title": "Psychological services to business leaders.", "content": "Psychological services to business leaders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995691"}
{"pmid": "20995706", "title": "World reconstruction and the concept of distribution of mental abilities in races, nations, and social strata.", "content": "World reconstruction and the concept of distribution of mental abilities in races, nations, and social strata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995706"}
{"pmid": "20995695", "title": "Six years after; a study of predictions [probation of criminals].", "content": "Six years after; a study of predictions [probation of criminals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995695"}
{"pmid": "20995707", "title": "Students' reactions to their given-names.", "content": "Students' reactions to their given-names.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995707"}
{"pmid": "20995708", "title": "The sociological validity of primary social attitude scale No. 1: religionism.", "content": "The sociological validity of primary social attitude scale No. 1: religionism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995708"}
{"pmid": "20995709", "title": "A study of some physiological differences between musicians and non-musicians; blood-pressure.", "content": "A study of some physiological differences between musicians and non-musicians; blood-pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995709"}
{"pmid": "20995710", "title": "A correlation between age and antipathy.", "content": "A correlation between age and antipathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995710"}
{"pmid": "20995692", "title": "Some professional problems of the consulting psychologist.", "content": "Some professional problems of the consulting psychologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995692"}
{"pmid": "20995711", "title": "Is antipathy the antithesis of sympathy?", "content": "Is antipathy the antithesis of sympathy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995711"}
{"pmid": "20995712", "title": "A comparison of the new revised Stanford-Binet, the Bellevue Scale, and certain group tests of intelligence.", "content": "A comparison of the new revised Stanford-Binet, the Bellevue Scale, and certain group tests of intelligence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995712"}
{"pmid": "20995713", "title": "Unemployment and mental health.", "content": "Unemployment and mental health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995713"}
{"pmid": "20995714", "title": "Observation in children's homes.", "content": "Observation in children's homes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995714"}
{"pmid": "20995715", "title": "Child victims of the war.", "content": "Child victims of the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995715"}
{"pmid": "20995716", "title": "The validity of personality questionnaires.", "content": "The validity of personality questionnaires.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995716"}
{"pmid": "20995717", "title": "The present status of psychology in South America.", "content": "The present status of psychology in South America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995717"}
{"pmid": "20995718", "title": "Rabies.", "content": "Rabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995718"}
{"pmid": "20995719", "title": "Fulton County reviews syphilis clinic records.", "content": "Fulton County reviews syphilis clinic records.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995719"}
{"pmid": "20995728", "title": "Expanded chronic disease program needed.", "content": "Expanded chronic disease program needed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995728"}
{"pmid": "20995729", "title": "Ten years of premarital blood test law.", "content": "Ten years of premarital blood test law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995729"}
{"pmid": "20995730", "title": "Florida's public health problems and what is needed to combat them.", "content": "Florida's public health problems and what is needed to combat them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995730"}
{"pmid": "20995731", "title": "Teamwork in the eradication of tuberculosis.", "content": "Teamwork in the eradication of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995731"}
{"pmid": "20995732", "title": "Nursing and the public health.", "content": "Nursing and the public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995732"}
{"pmid": "20995733", "title": "Ophthalmia neonatorum.", "content": "Ophthalmia neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995733"}
{"pmid": "20995734", "title": "The midwifery services; retrospect and prospect.", "content": "The midwifery services; retrospect and prospect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995734"}
{"pmid": "20995736", "title": "OF the heights of water closets.", "content": "OF the heights of water closets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995736"}
{"pmid": "20995735", "title": "Heavy pollution of an inland reservoir by seagulls.", "content": "Heavy pollution of an inland reservoir by seagulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995735"}
{"pmid": "20995737", "title": "DIPHTHERIA immunisation campaign.", "content": "DIPHTHERIA immunisation campaign.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995737"}
{"pmid": "20995738", "title": "Bread.", "content": "Bread.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995738"}
{"pmid": "20995739", "title": "Nutrition of Liverpool school children.", "content": "Nutrition of Liverpool school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995739"}
{"pmid": "20995740", "title": "Epidemic jaundice.", "content": "Epidemic jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995740"}
{"pmid": "20995741", "title": "The public health aspect of industrial medicine.", "content": "The public health aspect of industrial medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995741"}
{"pmid": "20995742", "title": "Cases of poliomyelitis occurring in Philadelphia in 1945.", "content": "Cases of poliomyelitis occurring in Philadelphia in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995742"}
{"pmid": "20995743", "title": "The challenge of the rheumatic problem to public health.", "content": "The challenge of the rheumatic problem to public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995743"}
{"pmid": "20995744", "title": "The cleansing and sterilisation of mess tins in the field.", "content": "The cleansing and sterilisation of mess tins in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995744"}
{"pmid": "20995745", "title": "The present position of pertussis prophylaxis and control.", "content": "The present position of pertussis prophylaxis and control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995745"}
{"pmid": "20995746", "title": "Premature births in Warwickshire, 1945.", "content": "Premature births in Warwickshire, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995746"}
{"pmid": "20995747", "title": "Sickness absenteeism among industrial workers, third and fourth quarters of 1945.", "content": "Sickness absenteeism among industrial workers, third and fourth quarters of 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995747"}
{"pmid": "20995748", "title": "An epidemic of a severe pneumonitis in the Bayou region of Louisiana; histopathology in laboratory animals.", "content": "An epidemic of a severe pneumonitis in the Bayou region of Louisiana; histopathology in laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995748"}
{"pmid": "20995749", "title": "Some epidemiological aspects of sensitivity to histoplasmin and tuberculin.", "content": "Some epidemiological aspects of sensitivity to histoplasmin and tuberculin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995749"}
{"pmid": "20995750", "title": "Tuberculosis throughout the world; the prewar distribution of tuberculosis throughout the world.", "content": "Tuberculosis throughout the world; the prewar distribution of tuberculosis throughout the world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995750"}
{"pmid": "20995752", "title": "DDT in paradichlorobenzene as a larvicide.", "content": "DDT in paradichlorobenzene as a larvicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995752"}
{"pmid": "20995751", "title": "An analysis of the design and performance of airplane exhaust generators for the production of DDT aerosols in the control of Anopheles quadrimaculatus.", "content": "An analysis of the design and performance of airplane exhaust generators for the production of DDT aerosols in the control of Anopheles quadrimaculatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995751"}
{"pmid": "20995753", "title": "The United States Public Health Service Communicable Disease Center.", "content": "The United States Public Health Service Communicable Disease Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995753"}
{"pmid": "20995754", "title": "Time per service in a children's dental clinic.", "content": "Time per service in a children's dental clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995754"}
{"pmid": "20995755", "title": "Tularemic pneumonia; treatment with streptomycin.", "content": "Tularemic pneumonia; treatment with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995755"}
{"pmid": "20995756", "title": "Winter survival of Aedes aegypti in Houston, Texas.", "content": "Winter survival of Aedes aegypti in Houston, Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995756"}
{"pmid": "20995757", "title": "Precipitin technique for determining mosquito blood meals.", "content": "Precipitin technique for determining mosquito blood meals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995757"}
{"pmid": "20995759", "title": "Charter for world health.", "content": "Charter for world health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995759"}
{"pmid": "20995758", "title": "WORLD Health Organization.", "content": "WORLD Health Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995758"}
{"pmid": "20995760", "title": "CONSTITUTION of the World Health Organization.", "content": "CONSTITUTION of the World Health Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995760"}
{"pmid": "20995762", "title": "Interlobar empyema.", "content": "Interlobar empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995762"}
{"pmid": "20995761", "title": "Roentgenological manifestations of primary pulmonary coccidioidomycosis.", "content": "Roentgenological manifestations of primary pulmonary coccidioidomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995761"}
{"pmid": "20995763", "title": "Multiple fractures in the long bones of infants suffering from chronic subdural hematoma.", "content": "Multiple fractures in the long bones of infants suffering from chronic subdural hematoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995763"}
{"pmid": "20995764", "title": "Polyostotic fibrous dysplasia and osteopathia condensans disseminata.", "content": "Polyostotic fibrous dysplasia and osteopathia condensans disseminata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995764"}
{"pmid": "20995765", "title": "Traumatic pneumocephalus associated with cerebrospinal otorrhea.", "content": "Traumatic pneumocephalus associated with cerebrospinal otorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995765"}
{"pmid": "20995766", "title": "Congenital talonavicular synostosis associated with hereditary multiple ankylosing arthropathies.", "content": "Congenital talonavicular synostosis associated with hereditary multiple ankylosing arthropathies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995766"}
{"pmid": "20995767", "title": "The pathogenesis of Charcots joint.", "content": "The pathogenesis of Charcots joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995767"}
{"pmid": "20995768", "title": "A new series of radiopaque compounds; chemical structures, channels of excretion and roentgenographic uses.", "content": "A new series of radiopaque compounds; chemical structures, channels of excretion and roentgenographic uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995768"}
{"pmid": "20995769", "title": "Capsules and inserter for the use of radium cells in the treatment of cancer of the uterine fundus.", "content": "Capsules and inserter for the use of radium cells in the treatment of cancer of the uterine fundus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995769"}
{"pmid": "20995770", "title": "Irradiation sickness; histamine effect treated with benadryl.", "content": "Irradiation sickness; histamine effect treated with benadryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995770"}
{"pmid": "20995771", "title": "Some historical data relating to the discovery of the roentgen rays.", "content": "Some historical data relating to the discovery of the roentgen rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995771"}
{"pmid": "20995772", "title": "Rollin Howard Stevens, a pioneer in radiology and cancer.", "content": "Rollin Howard Stevens, a pioneer in radiology and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995772"}
{"pmid": "20995773", "title": "Gas formation in abdominal abscesses; a roentgen study.", "content": "Gas formation in abdominal abscesses; a roentgen study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995773"}
{"pmid": "20995774", "title": "Lymphoepithelioma.", "content": "Lymphoepithelioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995774"}
{"pmid": "20995776", "title": "Solitary cyst of the calcaneus.", "content": "Solitary cyst of the calcaneus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995776"}
{"pmid": "20995775", "title": "Significance of the sacroiliac findings in Marie-Strumpell's spondylitis.", "content": "Significance of the sacroiliac findings in Marie-Strumpell's spondylitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995775"}
{"pmid": "20995777", "title": "Pulmonary torulosis.", "content": "Pulmonary torulosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995777"}
{"pmid": "20995778", "title": "Congenital cystic disease of the lung.", "content": "Congenital cystic disease of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995778"}
{"pmid": "20995779", "title": "The normal lateral retrograde pyelogram.", "content": "The normal lateral retrograde pyelogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995779"}
{"pmid": "20995780", "title": "Measurement of resolving power of intensifying screens.", "content": "Measurement of resolving power of intensifying screens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995780"}
{"pmid": "20995781", "title": "Roentgen findings in erythema nodosum.", "content": "Roentgen findings in erythema nodosum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995781"}
{"pmid": "20995782", "title": "Versatile erect Bucky for private office radiography with description of horizontal Bucky table mounted on floor track.", "content": "Versatile erect Bucky for private office radiography with description of horizontal Bucky table mounted on floor track.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995782"}
{"pmid": "20995783", "title": "Unsuspected pneumoperitoneum.", "content": "Unsuspected pneumoperitoneum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995783"}
{"pmid": "20995784", "title": "Absorption of pantopaque following myelography.", "content": "Absorption of pantopaque following myelography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995784"}
{"pmid": "20995785", "title": "Experience with curare in anesthesia.", "content": "Experience with curare in anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995785"}
{"pmid": "20995787", "title": "Early postoperative ambulation.", "content": "Early postoperative ambulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995787"}
{"pmid": "20995786", "title": "Thiouracil in the treatment of thyrotoxicosis; experience of the Thyroid Clinic of the Columbia-Presbyterian Medical Center.", "content": "Thiouracil in the treatment of thyrotoxicosis; experience of the Thyroid Clinic of the Columbia-Presbyterian Medical Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995786"}
{"pmid": "20995788", "title": "The effect of evisceration upon traumatic abdominal wounds.", "content": "The effect of evisceration upon traumatic abdominal wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995788"}
{"pmid": "20995789", "title": "Orthopedic surgery in the European Theater of Operations.", "content": "Orthopedic surgery in the European Theater of Operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995789"}
{"pmid": "20995790", "title": "Laminectomy for Pott's paraplegia.", "content": "Laminectomy for Pott's paraplegia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995790"}
{"pmid": "20995791", "title": "Indications and results of surgery of the autonomic nervous system in Naval personnel.", "content": "Indications and results of surgery of the autonomic nervous system in Naval personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995791"}
{"pmid": "20995792", "title": "Granular cell myoblastoma of the mammary gland.", "content": "Granular cell myoblastoma of the mammary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995792"}
{"pmid": "20995793", "title": "Combined roentgen radiation and surgical treatment of large benign giant cell tumors of bone.", "content": "Combined roentgen radiation and surgical treatment of large benign giant cell tumors of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995793"}
{"pmid": "20995794", "title": "Epithelioma of the anus.", "content": "Epithelioma of the anus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995794"}
{"pmid": "20995795", "title": "Cushing's syndrome.", "content": "Cushing's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995795"}
{"pmid": "20995796", "title": "Acute intussusception in infants and children.", "content": "Acute intussusception in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995796"}
{"pmid": "20995798", "title": "A study in articular replacement.", "content": "A study in articular replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995798"}
{"pmid": "20995797", "title": "Prevention of wound infection by the injection of nontoxic antibacterial substances.", "content": "Prevention of wound infection by the injection of nontoxic antibacterial substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995797"}
{"pmid": "20995799", "title": "An approach to resections of the esophagus and gastric cardia.", "content": "An approach to resections of the esophagus and gastric cardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995799"}
{"pmid": "20995800", "title": "A report on trench foot and cold injuries in the European Theater of Operations, 1944-1945.", "content": "A report on trench foot and cold injuries in the European Theater of Operations, 1944-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995800"}
{"pmid": "20995801", "title": "War-time activities of the National Research Council and the Committee on Medical Research; with particular reference to team-work on studies of wounds and burns.", "content": "War-time activities of the National Research Council and the Committee on Medical Research; with particular reference to team-work on studies of wounds and burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995801"}
{"pmid": "20995802", "title": "The effect of pentothal sodium on mean arterial blood pressure in the presence of high spinal cord paralysis.", "content": "The effect of pentothal sodium on mean arterial blood pressure in the presence of high spinal cord paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995802"}
{"pmid": "20995803", "title": "The importance of whole blood transfusions in the management of severe burns.", "content": "The importance of whole blood transfusions in the management of severe burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995803"}
{"pmid": "20995805", "title": "Massive pancreatic hemorrhage.", "content": "Massive pancreatic hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995805"}
{"pmid": "20995804", "title": "Lesions of the musculotendinous cuff of the shoulder; observations on the pathology, course and treatment of calcific deposits.", "content": "Lesions of the musculotendinous cuff of the shoulder; observations on the pathology, course and treatment of calcific deposits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995804"}
{"pmid": "20995806", "title": "War injuries of the chest.", "content": "War injuries of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995806"}
{"pmid": "20995807", "title": "Notes on operative technic in neurosurgery.", "content": "Notes on operative technic in neurosurgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995807"}
{"pmid": "20995808", "title": "Posterior cordotomy for relief of phantom limb pain.", "content": "Posterior cordotomy for relief of phantom limb pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995808"}
{"pmid": "20995809", "title": "Streptomycin in surgical infections; infections of the genito-urinary tract.", "content": "Streptomycin in surgical infections; infections of the genito-urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995809"}
{"pmid": "20995810", "title": "Antral gastritis and spasm; their clinical and surgical significance.", "content": "Antral gastritis and spasm; their clinical and surgical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995810"}
{"pmid": "20995811", "title": "Displacement of medial epicondyle of humerus into the elbow joint.", "content": "Displacement of medial epicondyle of humerus into the elbow joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995811"}
{"pmid": "20995812", "title": "A technic for combined measurement of motility and electric action potentials in the human intestine.", "content": "A technic for combined measurement of motility and electric action potentials in the human intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995812"}
{"pmid": "20995813", "title": "The treatment of compound fractures in the Italian campaign.", "content": "The treatment of compound fractures in the Italian campaign.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995813"}
{"pmid": "20995814", "title": "Gunshot wounds of the abdomen.", "content": "Gunshot wounds of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995814"}
{"pmid": "20995815", "title": "Skingrafting the burned dorsum of the hand.", "content": "Skingrafting the burned dorsum of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995815"}
{"pmid": "20995816", "title": "The thoraco-abdominal casualty.", "content": "The thoraco-abdominal casualty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995816"}
{"pmid": "20995817", "title": "Unusual metastatic manifestations of breast carcinoma; metastasis to the mandible with a report of five cases.", "content": "Unusual metastatic manifestations of breast carcinoma; metastasis to the mandible with a report of five cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995817"}
{"pmid": "20995818", "title": "The pelvic floor in parturition.", "content": "The pelvic floor in parturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995818"}
{"pmid": "20995819", "title": "An evaluation of certain drugs used to maintain blood pressure during spinal anesthesia; comparison of ephedrine, paredrine, pitressin-ephedrine and methedrine in 2500 cases.", "content": "An evaluation of certain drugs used to maintain blood pressure during spinal anesthesia; comparison of ephedrine, paredrine, pitressin-ephedrine and methedrine in 2500 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995819"}
{"pmid": "20995820", "title": "The use of tyrothricin in surgical infections.", "content": "The use of tyrothricin in surgical infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995820"}
{"pmid": "20995822", "title": "Repair of vesicovaginal fistula caused by radiation.", "content": "Repair of vesicovaginal fistula caused by radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995822"}
{"pmid": "20995821", "title": "The identification of Clostridium welchii in mixed cultures and débrided tissue and determination of sensitivity of the organism to penicillin.", "content": "The identification of Clostridium welchii in mixed cultures and débrided tissue and determination of sensitivity of the organism to penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995821"}
{"pmid": "20995823", "title": "Mandibular tumors; a clinical, roentgenographic, and histopathologic study.", "content": "Mandibular tumors; a clinical, roentgenographic, and histopathologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995823"}
{"pmid": "20995824", "title": "The Cherney incision as applied to the surgery of the lower ureter and bladder.", "content": "The Cherney incision as applied to the surgery of the lower ureter and bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995824"}
{"pmid": "20995825", "title": "The exposure of high lesions of the sciatic nerve.", "content": "The exposure of high lesions of the sciatic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995825"}
{"pmid": "20995826", "title": "Cineplastic forearm amputations and prostheses.", "content": "Cineplastic forearm amputations and prostheses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995826"}
{"pmid": "20995827", "title": "The effect of pulmonary resuscitative procedures upon the circulation as demonstrated by the use of radioactive sodium.", "content": "The effect of pulmonary resuscitative procedures upon the circulation as demonstrated by the use of radioactive sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995827"}
{"pmid": "20995828", "title": "Cancellous bone grafts for infected bone defects; a single stage procedure.", "content": "Cancellous bone grafts for infected bone defects; a single stage procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995828"}
{"pmid": "20995829", "title": "Outlet pelvimetry; a commentary, and the presentation of a pelvimeter for measuring the symphysis and sacral biparietal distance.", "content": "Outlet pelvimetry; a commentary, and the presentation of a pelvimeter for measuring the symphysis and sacral biparietal distance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995829"}
{"pmid": "20995830", "title": "The absorbable hemostatic agents.", "content": "The absorbable hemostatic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995830"}
{"pmid": "20995831", "title": "Splenectomy, with special reference to its historical background; the indications and rationale, and a comparison of reported mortality.", "content": "Splenectomy, with special reference to its historical background; the indications and rationale, and a comparison of reported mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995831"}
{"pmid": "20995832", "title": "Infections of the foot.", "content": "Infections of the foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995832"}
{"pmid": "20995833", "title": "Senile enlargement of the prostate.", "content": "Senile enlargement of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995833"}
{"pmid": "20995834", "title": "The surgery of enlarged prostate.", "content": "The surgery of enlarged prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995834"}
{"pmid": "20995835", "title": "Volvulus of the stomach.", "content": "Volvulus of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995835"}
{"pmid": "20995836", "title": "Hydatid cyst-thyroid.", "content": "Hydatid cyst-thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995836"}
{"pmid": "20995837", "title": "Osteolytic sarcoma of the lower end of the radius.", "content": "Osteolytic sarcoma of the lower end of the radius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995837"}
{"pmid": "20995838", "title": "Progress in physical medicine during the past twenty-five years.", "content": "Progress in physical medicine during the past twenty-five years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995838"}
{"pmid": "20995839", "title": "Medical implications of convalescence.", "content": "Medical implications of convalescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995839"}
{"pmid": "20995840", "title": "Physical medicine as recognized specialty is brought out in demonstrations at the AMA Convention in San Francisco.", "content": "Physical medicine as recognized specialty is brought out in demonstrations at the AMA Convention in San Francisco.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995840"}
{"pmid": "20995841", "title": "Electroshock therapy with 200 milliamperes for ten seconds.", "content": "Electroshock therapy with 200 milliamperes for ten seconds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995841"}
{"pmid": "20995842", "title": "Rapid rehabilitation following hand injuries.", "content": "Rapid rehabilitation following hand injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995842"}
{"pmid": "20995843", "title": "The registry examination.", "content": "The registry examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995843"}
{"pmid": "20995852", "title": "The treatment of amoebiasis.", "content": "The treatment of amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995852"}
{"pmid": "20995853", "title": "Plague.", "content": "Plague.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995853"}
{"pmid": "20995854", "title": "Apical tuberculosis, a roentgenological technique for its early recognition with some pathogenetic applications.", "content": "Apical tuberculosis, a roentgenological technique for its early recognition with some pathogenetic applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995854"}
{"pmid": "20995855", "title": "Employment of ex-tuberculous patients.", "content": "Employment of ex-tuberculous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995855"}
{"pmid": "20995856", "title": "Patients' information about tuberculosis; a survey with a standardized questionnaire.", "content": "Patients' information about tuberculosis; a survey with a standardized questionnaire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995856"}
{"pmid": "20995857", "title": "Results of pneumonolysis.", "content": "Results of pneumonolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995857"}
{"pmid": "20995858", "title": "Vaccination with the vole bacillus (Wells); protective value of percutaneous and intracutaneous vaccination; observations on multiple puncture vaccination on man.", "content": "Vaccination with the vole bacillus (Wells); protective value of percutaneous and intracutaneous vaccination; observations on multiple puncture vaccination on man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995858"}
{"pmid": "20995859", "title": "R1 strain of tubercle bacillus; its dissociation and virulence of variants in normal and silicotic guinea pigs.", "content": "R1 strain of tubercle bacillus; its dissociation and virulence of variants in normal and silicotic guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995859"}
{"pmid": "20995860", "title": "History of H37 strain of tubercle bacillus.", "content": "History of H37 strain of tubercle bacillus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995860"}
{"pmid": "20995861", "title": "Cultures of pulmonary secretions; their accuracy in the evaluation of activity in pulmonary tuberculosis.", "content": "Cultures of pulmonary secretions; their accuracy in the evaluation of activity in pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995861"}
{"pmid": "20995862", "title": "Plasma and urinary ascorbic acid in tuberculous patients.", "content": "Plasma and urinary ascorbic acid in tuberculous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995862"}
{"pmid": "20995863", "title": "Effects of intranasal inoculation with tubercle bacilli on vitamin A stores and tissues of mice and rats.", "content": "Effects of intranasal inoculation with tubercle bacilli on vitamin A stores and tissues of mice and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995863"}
{"pmid": "20995864", "title": "Sanitation of the air.", "content": "Sanitation of the air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995864"}
{"pmid": "20995867", "title": "Embryoma of the kidney in the adult.", "content": "Embryoma of the kidney in the adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995867"}
{"pmid": "20995869", "title": "Infection of the urinary tract in the female due to Trichomonas vaginalis.", "content": "Infection of the urinary tract in the female due to Trichomonas vaginalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995869"}
{"pmid": "20995868", "title": "The retrograde movement of ureteric calculi.", "content": "The retrograde movement of ureteric calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995868"}
{"pmid": "20995870", "title": "Dislocation of the penis.", "content": "Dislocation of the penis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995870"}
{"pmid": "20995871", "title": "Solitary benign papilloma of the ureter.", "content": "Solitary benign papilloma of the ureter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995871"}
{"pmid": "20995872", "title": "Spontaneous rupture of a leiomyosarcoma of the bladder.", "content": "Spontaneous rupture of a leiomyosarcoma of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995872"}
{"pmid": "20995873", "title": "Benign enlargement of the prostate.", "content": "Benign enlargement of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995873"}
{"pmid": "20995874", "title": "The female urethra.", "content": "The female urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995874"}
{"pmid": "20995875", "title": "Stricture of the female urethra.", "content": "Stricture of the female urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995875"}
{"pmid": "20995876", "title": "The treatment of fibrosis of the corpora cavernosa.", "content": "The treatment of fibrosis of the corpora cavernosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995876"}
{"pmid": "20995877", "title": "A study of local anaesthesia in office urology.", "content": "A study of local anaesthesia in office urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995877"}
{"pmid": "20995878", "title": "The differential diagnosis between renal colic and acute appendicitis.", "content": "The differential diagnosis between renal colic and acute appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995878"}
{"pmid": "20995879", "title": "Syphilis of bone.", "content": "Syphilis of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995879"}
{"pmid": "20995880", "title": "An examination of some data on the relationship of blood donation to false positive serologic tests for syphilis.", "content": "An examination of some data on the relationship of blood donation to false positive serologic tests for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995880"}
{"pmid": "20995881", "title": "A case of herpes zoster with unusual distribution.", "content": "A case of herpes zoster with unusual distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995881"}
{"pmid": "20995882", "title": "Treatment of cutaneous disorders by means of a resin, polymer of hydroxybenzyl alcohol (S. B. S.).", "content": "Treatment of cutaneous disorders by means of a resin, polymer of hydroxybenzyl alcohol (S. B. S.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995882"}
{"pmid": "20995883", "title": "A treatment for the superficial fungus infections of the skin.", "content": "A treatment for the superficial fungus infections of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995883"}
{"pmid": "20995885", "title": "Folklore and more regarding nails.", "content": "Folklore and more regarding nails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995885"}
{"pmid": "20995884", "title": "[KIDNEY surgery].", "content": "[KIDNEY surgery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995884"}
{"pmid": "20995886", "title": "Report upon experiments conducted to establish the tolerance of turkeys to DDT.", "content": "Report upon experiments conducted to establish the tolerance of turkeys to DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995886"}
{"pmid": "20995887", "title": "A summary of the use of phenothiazine in the control of cecal worms and in the prevention of blackhead.", "content": "A summary of the use of phenothiazine in the control of cecal worms and in the prevention of blackhead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995887"}
{"pmid": "20995888", "title": "Flank ovariectomy in the mare.", "content": "Flank ovariectomy in the mare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995888"}
{"pmid": "20995889", "title": "Immunological differences between the Pasteur fixed-virus strains and the Venezuelan paralytic rabies strains.", "content": "Immunological differences between the Pasteur fixed-virus strains and the Venezuelan paralytic rabies strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995889"}
{"pmid": "20995890", "title": "An apparently new transmissible disease of cattle.", "content": "An apparently new transmissible disease of cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995890"}
{"pmid": "20995891", "title": "The antibacterial action of streptomycin.", "content": "The antibacterial action of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995891"}
{"pmid": "20995892", "title": "Teat surgery.", "content": "Teat surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995892"}
{"pmid": "20995893", "title": "The diagnosis of diseases of lambs.", "content": "The diagnosis of diseases of lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995893"}
{"pmid": "20995895", "title": "Constriction in cervical region of a palm civet.", "content": "Constriction in cervical region of a palm civet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995895"}
{"pmid": "20995894", "title": "Studies in cowpox; a note on the fungal flora of bovine teat and udder lesions.", "content": "Studies in cowpox; a note on the fungal flora of bovine teat and udder lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995894"}
{"pmid": "20995896", "title": "A successful equine laparotomy.", "content": "A successful equine laparotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995896"}
{"pmid": "20995898", "title": "An unusual structure associated with bovine necrotic mastitis.", "content": "An unusual structure associated with bovine necrotic mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995898"}
{"pmid": "20995897", "title": "Adamantinoma in the bovine.", "content": "Adamantinoma in the bovine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995897"}
{"pmid": "20995899", "title": "Colic due to intestinal calculi.", "content": "Colic due to intestinal calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995899"}
{"pmid": "20995900", "title": "Dystocia with emphysematous fetus delivered by caesarean section.", "content": "Dystocia with emphysematous fetus delivered by caesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995900"}
{"pmid": "20995901", "title": "Lymphocytoma in a cow's heart.", "content": "Lymphocytoma in a cow's heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995901"}
{"pmid": "20995902", "title": "Studies on vibrionic infection of sheep; the agglutination test as a means of diagnosis.", "content": "Studies on vibrionic infection of sheep; the agglutination test as a means of diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995902"}
{"pmid": "20995904", "title": "Louping-ill antiserum.", "content": "Louping-ill antiserum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995904"}
{"pmid": "20995903", "title": "Studies on vibrionic infection of sheep; some observations on the antigenic relation ship between strains of Vibrio foetus.", "content": "Studies on vibrionic infection of sheep; some observations on the antigenic relation ship between strains of Vibrio foetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995903"}
{"pmid": "20995905", "title": "Experimental infections in virgin heifers with Trichomonas foetus in vaccinated and unvaccinated animals.", "content": "Experimental infections in virgin heifers with Trichomonas foetus in vaccinated and unvaccinated animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995905"}
{"pmid": "20995906", "title": "Studies on the clinical and parasitological aspects of canine demodectic mange.", "content": "Studies on the clinical and parasitological aspects of canine demodectic mange.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995906"}
{"pmid": "20995907", "title": "The prophylaxis of bovine blackquarter.", "content": "The prophylaxis of bovine blackquarter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995907"}
{"pmid": "20995909", "title": "Newcastle disease in Pennsylvania.", "content": "Newcastle disease in Pennsylvania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995909"}
{"pmid": "20995908", "title": "Experimental Staphylococcus aureus mastitis in sheep; treatment trial with sulphonamides or staphylococcus toxoid.", "content": "Experimental Staphylococcus aureus mastitis in sheep; treatment trial with sulphonamides or staphylococcus toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995908"}
{"pmid": "20995910", "title": "Vaccine to save water buffalo for field work rushed to China.", "content": "Vaccine to save water buffalo for field work rushed to China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995910"}
{"pmid": "20995911", "title": "A case of duplicitas in a calf.", "content": "A case of duplicitas in a calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995911"}
{"pmid": "20995912", "title": "Insemination with gelatinised sperm in paraffined cellophane tubes.", "content": "Insemination with gelatinised sperm in paraffined cellophane tubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995912"}
{"pmid": "20995913", "title": "Clinical gas-gangrene in the neck of a black greyhound treated by oxygen infiltration.", "content": "Clinical gas-gangrene in the neck of a black greyhound treated by oxygen infiltration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995913"}
{"pmid": "20995914", "title": "The hormonal tests for equine pregnancy.", "content": "The hormonal tests for equine pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995914"}
{"pmid": "20995917", "title": "Notes on the shoeing of Ceylon bulls by itinerant farriers.", "content": "Notes on the shoeing of Ceylon bulls by itinerant farriers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995917"}
{"pmid": "20995915", "title": "A comparing-chamber for microscopic examination of undiluted bull semen.", "content": "A comparing-chamber for microscopic examination of undiluted bull semen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995915"}
{"pmid": "20995916", "title": "The treatment of purulent conjunctivitis in domesticated animals with a mixed sulphanilamide-sulphathiazole powder; a note on the experimental treatment of two cases.", "content": "The treatment of purulent conjunctivitis in domesticated animals with a mixed sulphanilamide-sulphathiazole powder; a note on the experimental treatment of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995916"}
{"pmid": "20995918", "title": "Case report; rabies in a heifer.", "content": "Case report; rabies in a heifer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995918"}
{"pmid": "20995919", "title": "The anatomy and function of the foreleg in salamander locomotion.", "content": "The anatomy and function of the foreleg in salamander locomotion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995919"}
{"pmid": "20995920", "title": "The relation of hydrostatic conditions in the uterus to the size and shape of the conceptus during pregnancy; a concept of uterine accommodation.", "content": "The relation of hydrostatic conditions in the uterus to the size and shape of the conceptus during pregnancy; a concept of uterine accommodation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995920"}
{"pmid": "20995922", "title": "Glass and steel containers for human anatomy.", "content": "Glass and steel containers for human anatomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995922"}
{"pmid": "20995921", "title": "A silvergelatin method for staining nerve fibers.", "content": "A silvergelatin method for staining nerve fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995921"}
{"pmid": "20995923", "title": "Fusion of notochord to neural tube in a human embryo of the sixth week.", "content": "Fusion of notochord to neural tube in a human embryo of the sixth week.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995923"}
{"pmid": "20995925", "title": "Form and behavior of adult mammalian skeletal muscle in vitro.", "content": "Form and behavior of adult mammalian skeletal muscle in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995925"}
{"pmid": "20995924", "title": "Response of prepuberal male mice to equine gonadotropin.", "content": "Response of prepuberal male mice to equine gonadotropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995924"}
{"pmid": "20995926", "title": "The time of ovulation in the monkey.", "content": "The time of ovulation in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995926"}
{"pmid": "20995928", "title": "The sequence of epiphysial union in the opossum.", "content": "The sequence of epiphysial union in the opossum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995928"}
{"pmid": "20995927", "title": "An anomalous middle meningeal artery.", "content": "An anomalous middle meningeal artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995927"}
{"pmid": "20995930", "title": "The potentiation of tetanus toxin by broth and serum.", "content": "The potentiation of tetanus toxin by broth and serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995930"}
{"pmid": "20995929", "title": "Antimalarial and antibacterial substances separated from higher plants.", "content": "Antimalarial and antibacterial substances separated from higher plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995929"}
{"pmid": "20995931", "title": "Electron microscopy of Bacterium tularense.", "content": "Electron microscopy of Bacterium tularense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995931"}
{"pmid": "20995932", "title": "The nutrition of phytopathogenic bacteria; the genus Agrobacterium.", "content": "The nutrition of phytopathogenic bacteria; the genus Agrobacterium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995932"}
{"pmid": "20995934", "title": "Studies on lyophiled cultures; lyophile storage of cultures of Rhizobium leguminosarum.", "content": "Studies on lyophiled cultures; lyophile storage of cultures of Rhizobium leguminosarum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995934"}
{"pmid": "20995933", "title": "The amino acid composition of microorganisms.", "content": "The amino acid composition of microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995933"}
{"pmid": "20995935", "title": "Organic growth essentials of the aerobic nonsulfur photosynthetic bacteria.", "content": "Organic growth essentials of the aerobic nonsulfur photosynthetic bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995935"}
{"pmid": "20995936", "title": "Studies on the nutritional requirements of Streptomyces griseus for the formation of streptomycin.", "content": "Studies on the nutritional requirements of Streptomyces griseus for the formation of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995936"}
{"pmid": "20995938", "title": "A new laboratory fermenter for yeast production investigations.", "content": "A new laboratory fermenter for yeast production investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995938"}
{"pmid": "20995937", "title": "Proteinase production by Bacillus subtilis.", "content": "Proteinase production by Bacillus subtilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995937"}
{"pmid": "20995940", "title": "A dilution plate counting method for certain strains of Bacterium tularense.", "content": "A dilution plate counting method for certain strains of Bacterium tularense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995940"}
{"pmid": "20995939", "title": "The isolation of Escherichia coliphage by means of cationic detergents.", "content": "The isolation of Escherichia coliphage by means of cationic detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995939"}
{"pmid": "20995941", "title": "The effect of serum upon dissociation in Brucella abortus; a demonstration of the role of selective environments in bacterial variation.", "content": "The effect of serum upon dissociation in Brucella abortus; a demonstration of the role of selective environments in bacterial variation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995941"}
{"pmid": "20995942", "title": "The reductase method for the determination of penicillin concentrations in body fluids.", "content": "The reductase method for the determination of penicillin concentrations in body fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995942"}
{"pmid": "20995943", "title": "The use of the rodent-adapted MEF1 strain of human poliomyelitis in neutralization tests with serum of apparently normal African natives.", "content": "The use of the rodent-adapted MEF1 strain of human poliomyelitis in neutralization tests with serum of apparently normal African natives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995943"}
{"pmid": "20995944", "title": "The tubercle bacillus as an indicator organism in quantitative studies of airborne infection; quantitative aerosol suspension of tubercle bacilli.", "content": "The tubercle bacillus as an indicator organism in quantitative studies of airborne infection; quantitative aerosol suspension of tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995944"}
{"pmid": "20995945", "title": "The tubercle bacillus as an indicator organism in quantitative studies of airborne infection; quantitative enumeration of tubercle bacilli in vivo.", "content": "The tubercle bacillus as an indicator organism in quantitative studies of airborne infection; quantitative enumeration of tubercle bacilli in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995945"}
{"pmid": "20995946", "title": "The nature of fibrositis; a study of the causation of myalgic lesion (rheumatic, traumatic, infective).", "content": "The nature of fibrositis; a study of the causation of myalgic lesion (rheumatic, traumatic, infective).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995946"}
{"pmid": "20995947", "title": "Weltmann coagulation reaction in rheumatoid arthritis.", "content": "Weltmann coagulation reaction in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995947"}
{"pmid": "20995948", "title": "The formol-gel test on plasma and serum in rheumatic cases; correlation studies and a suggestion that non-rouleaux-forming pathological globulins may be of significance in rheumatism.", "content": "The formol-gel test on plasma and serum in rheumatic cases; correlation studies and a suggestion that non-rouleaux-forming pathological globulins may be of significance in rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995948"}
{"pmid": "20995949", "title": "Necrobiotic nodules of rheumatoid arthritis type with lipoid deposition.", "content": "Necrobiotic nodules of rheumatoid arthritis type with lipoid deposition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995949"}
{"pmid": "20995950", "title": "Fibrositis and beta-diethylamino ethyl dehydrocholate.", "content": "Fibrositis and beta-diethylamino ethyl dehydrocholate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995950"}
{"pmid": "20995951", "title": "The cold-reaction test for peripheral vasomotor disturbances in rheumatism.", "content": "The cold-reaction test for peripheral vasomotor disturbances in rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995951"}
{"pmid": "20995952", "title": "Ankylosing spondylitis; review.", "content": "Ankylosing spondylitis; review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995952"}
{"pmid": "20995953", "title": "Vascular injuries due to cold with particular reference to the late phase of trench foot.", "content": "Vascular injuries due to cold with particular reference to the late phase of trench foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995953"}
{"pmid": "20995954", "title": "The contribution of the analytical chemist to protein chemistry.", "content": "The contribution of the analytical chemist to protein chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995954"}
{"pmid": "20995955", "title": "The use of specific precipitants in the amino acid analysis of proteins.", "content": "The use of specific precipitants in the amino acid analysis of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995955"}
{"pmid": "20995956", "title": "The isotope dilution method of amino acid analysis.", "content": "The isotope dilution method of amino acid analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995956"}
{"pmid": "20995957", "title": "Chromatographic and ion exchange methods of amino acid analysis.", "content": "Chromatographic and ion exchange methods of amino acid analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995957"}
{"pmid": "20995958", "title": "Microbiological methods in amino acid analysis.", "content": "Microbiological methods in amino acid analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995958"}
{"pmid": "20995960", "title": "Amino acid composition of simple proteins.", "content": "Amino acid composition of simple proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995960"}
{"pmid": "20995959", "title": "Enzymatic methods in amino acid analysis.", "content": "Enzymatic methods in amino acid analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995959"}
{"pmid": "20995961", "title": "SOME correlations between physico-chemical data and the amino acid composition of simple proteins.", "content": "SOME correlations between physico-chemical data and the amino acid composition of simple proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995961"}
{"pmid": "20995962", "title": "Biological oxidations and reductions.", "content": "Biological oxidations and reductions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995962"}
{"pmid": "20995963", "title": "Non-oxidative enzymes.", "content": "Non-oxidative enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995963"}
{"pmid": "20995964", "title": "Plant carbohydrates.", "content": "Plant carbohydrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995964"}
{"pmid": "20995965", "title": "The chemistry of the lipids.", "content": "The chemistry of the lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995965"}
{"pmid": "20995966", "title": "The chemistry of the proteins and amino acids.", "content": "The chemistry of the proteins and amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995966"}
{"pmid": "20995967", "title": "The chemistry of the steroids.", "content": "The chemistry of the steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995967"}
{"pmid": "20995968", "title": "Carbohydrate metabolism.", "content": "Carbohydrate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995968"}
{"pmid": "20995969", "title": "Fat metabolism.", "content": "Fat metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995969"}
{"pmid": "20995970", "title": "The metabolism of proteins and amino acids.", "content": "The metabolism of proteins and amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995970"}
{"pmid": "20995971", "title": "The vitamins.", "content": "The vitamins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995971"}
{"pmid": "20995972", "title": "The chemistry of the hormones.", "content": "The chemistry of the hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995972"}
{"pmid": "20995973", "title": "The biochemistry of teeth.", "content": "The biochemistry of teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995973"}
{"pmid": "20995974", "title": "Growth factors for micro-organisms.", "content": "Growth factors for micro-organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995974"}
{"pmid": "20995975", "title": "Photosynthesis.", "content": "Photosynthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995975"}
{"pmid": "20995976", "title": "The respiration of plants.", "content": "The respiration of plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995976"}
{"pmid": "20995977", "title": "The biochemistry of yeast.", "content": "The biochemistry of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995977"}
{"pmid": "20995978", "title": "Bacterial metabolism.", "content": "Bacterial metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995978"}
{"pmid": "20995980", "title": "Organic insecticides.", "content": "Organic insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995980"}
{"pmid": "20995979", "title": "Immunochemistry.", "content": "Immunochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995979"}
{"pmid": "20995981", "title": "The viruses.", "content": "The viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995981"}
{"pmid": "20995982", "title": "Inactivation and detoxication of pressor amines.", "content": "Inactivation and detoxication of pressor amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995982"}
{"pmid": "20995983", "title": "Stokes' law and the limiting conductance of organic ions.", "content": "Stokes' law and the limiting conductance of organic ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995983"}
{"pmid": "20995984", "title": "Studies in vapor-liquid equilibria; a new dynamic method for the determination of vapor pressures of liquids.", "content": "Studies in vapor-liquid equilibria; a new dynamic method for the determination of vapor pressures of liquids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995984"}
{"pmid": "20995985", "title": "Determination of the density of a fine powder.", "content": "Determination of the density of a fine powder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995985"}
{"pmid": "20995986", "title": "A correlation of structure with fastness to light of monoazo dyes.", "content": "A correlation of structure with fastness to light of monoazo dyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995986"}
{"pmid": "20995987", "title": "On the application and derivation of the new viscosity temperature relationship on liquids.", "content": "On the application and derivation of the new viscosity temperature relationship on liquids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995987"}
{"pmid": "20995988", "title": "Can a dental health card system succeed in high schools.", "content": "Can a dental health card system succeed in high schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995988"}
{"pmid": "20995991", "title": "DENTISTRY in wartime Germany.", "content": "DENTISTRY in wartime Germany.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995991"}
{"pmid": "20995992", "title": "Sears hydrocolloid impression technic in restorative dentistry.", "content": "Sears hydrocolloid impression technic in restorative dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995992"}
{"pmid": "20995993", "title": "A consideration of the possibility of hereditary diatheses in dental caries.", "content": "A consideration of the possibility of hereditary diatheses in dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995993"}
{"pmid": "20995989", "title": "The incidence of dental caries in Bombay.", "content": "The incidence of dental caries in Bombay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995989"}
{"pmid": "20995995", "title": "Normal functional occlusion; its importance in prevention and treatment of pyorrhea.", "content": "Normal functional occlusion; its importance in prevention and treatment of pyorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995995"}
{"pmid": "20995994", "title": "The porcelain-acrylic jacket crown.", "content": "The porcelain-acrylic jacket crown.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995994"}
{"pmid": "20995996", "title": "Psychologic problems associated with complete denture service.", "content": "Psychologic problems associated with complete denture service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995996"}
{"pmid": "20995997", "title": "Construction of immediate temporary bridge.", "content": "Construction of immediate temporary bridge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995997"}
{"pmid": "20995998", "title": "Fluorine and dental caries.", "content": "Fluorine and dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995998"}
{"pmid": "20995999", "title": "Further testimony from hearings on dental research and grants-in-aid-bills.", "content": "Further testimony from hearings on dental research and grants-in-aid-bills.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995999"}
{"pmid": "20996000", "title": "The biological production and therapeutic use of ammonia in the oral cavity in relation to dental caries prevention.", "content": "The biological production and therapeutic use of ammonia in the oral cavity in relation to dental caries prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996000"}
{"pmid": "20996001", "title": "A system of dental identification.", "content": "A system of dental identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996001"}
{"pmid": "20996002", "title": "A comparison of methods of treating Vincent's infection.", "content": "A comparison of methods of treating Vincent's infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996002"}
{"pmid": "20995990", "title": "Post-extraction hemorrhage.", "content": "Post-extraction hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20995990"}
{"pmid": "20996003", "title": "Comparative methods of using penicillin in the treatment of Vincent's infection and other oral lesions.", "content": "Comparative methods of using penicillin in the treatment of Vincent's infection and other oral lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996003"}
{"pmid": "20996005", "title": "The family and dental disease; dental disease (DMF) experience in parents and offspring.", "content": "The family and dental disease; dental disease (DMF) experience in parents and offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996005"}
{"pmid": "20996004", "title": "Fibrin foam and thrombin as used in the surgical removal of a large fibromyxoma of the mandible.", "content": "Fibrin foam and thrombin as used in the surgical removal of a large fibromyxoma of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996004"}
{"pmid": "20996006", "title": "TESTIMONY of the American Dental Association on Wagner-Murray-Dingell bill (S. 1606).", "content": "TESTIMONY of the American Dental Association on Wagner-Murray-Dingell bill (S. 1606).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996006"}
{"pmid": "20996007", "title": "The dentist and the dental laboratory.", "content": "The dentist and the dental laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996007"}
{"pmid": "20996008", "title": "Vincent's infection of the mouth.", "content": "Vincent's infection of the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996008"}
{"pmid": "20996009", "title": "Methods of Rh studies in a private hospital blood bank.", "content": "Methods of Rh studies in a private hospital blood bank.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996009"}
{"pmid": "20996010", "title": "The future of medical technology (as seen by a clinical pathologist).", "content": "The future of medical technology (as seen by a clinical pathologist).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996010"}
{"pmid": "20996011", "title": "Some applications of semi-micro chemistry to routine urinalysis.", "content": "Some applications of semi-micro chemistry to routine urinalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996011"}
{"pmid": "20996012", "title": "Canning drinking water.", "content": "Canning drinking water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996012"}
{"pmid": "20996013", "title": "Packing plant sanitation calls for good housekeeping.", "content": "Packing plant sanitation calls for good housekeeping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996013"}
{"pmid": "20996014", "title": "Quantitative effects of hypophysectomy on testis and prostate of dogs.", "content": "Quantitative effects of hypophysectomy on testis and prostate of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996014"}
{"pmid": "20996015", "title": "A method for locating radioactive elements in tissues by covering histological sections with a photographic emulsion.", "content": "A method for locating radioactive elements in tissues by covering histological sections with a photographic emulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996015"}
{"pmid": "20996016", "title": "Effect of thiouracil on the juvenile plumages of Brown Leghorn fowl.", "content": "Effect of thiouracil on the juvenile plumages of Brown Leghorn fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996016"}
{"pmid": "20996017", "title": "Pituitary-gonad interaction in immature female parabiotic rats.", "content": "Pituitary-gonad interaction in immature female parabiotic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996017"}
{"pmid": "20996018", "title": "The effect of adrenocorticotrophic hormone on the urinary excretion of sodium, chloride, potassium, nitrogen and glucose in normal rats.", "content": "The effect of adrenocorticotrophic hormone on the urinary excretion of sodium, chloride, potassium, nitrogen and glucose in normal rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996018"}
{"pmid": "20996019", "title": "The production of alimentary glycosuria by forced feeding in the rat.", "content": "The production of alimentary glycosuria by forced feeding in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996019"}
{"pmid": "20996020", "title": "A comparison of the acute effects of corticosterone and 17-hydroxycorticosterone on body weight and the urinary excretion of sodium, chloride, potassium, nitrogen and glucose in the normal rat.", "content": "A comparison of the acute effects of corticosterone and 17-hydroxycorticosterone on body weight and the urinary excretion of sodium, chloride, potassium, nitrogen and glucose in the normal rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996020"}
{"pmid": "20996021", "title": "Studies concerning the cause and purpose of menstruation.", "content": "Studies concerning the cause and purpose of menstruation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996021"}
{"pmid": "20996022", "title": "Chronic idiopathic hypoparathyroidism with superimposed Addison's disease in a child.", "content": "Chronic idiopathic hypoparathyroidism with superimposed Addison's disease in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996022"}
{"pmid": "20996023", "title": "Adrenocortical cancer with undulating fever in Addison's disease.", "content": "Adrenocortical cancer with undulating fever in Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996023"}
{"pmid": "20996024", "title": "A new sign on the climacteric.", "content": "A new sign on the climacteric.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996024"}
{"pmid": "20996025", "title": "A simple test for hormone deficiency in the male.", "content": "A simple test for hormone deficiency in the male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996025"}
{"pmid": "20996026", "title": "Early production of steroid hormone by trophoblast.", "content": "Early production of steroid hormone by trophoblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996026"}
{"pmid": "20996027", "title": "Education for marriage and family life.", "content": "Education for marriage and family life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996027"}
{"pmid": "20996028", "title": "The action of adrenaline on the excised human uterus; with a short additional note on the action of quinine.", "content": "The action of adrenaline on the excised human uterus; with a short additional note on the action of quinine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996028"}
{"pmid": "20996029", "title": "Moulding of the foetal head; a compensatory mechanism.", "content": "Moulding of the foetal head; a compensatory mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996029"}
{"pmid": "20996030", "title": "Acute inversion of the uterus.", "content": "Acute inversion of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996030"}
{"pmid": "20996031", "title": "Diabetes insipidus in association with postpartum pituitary necrosis.", "content": "Diabetes insipidus in association with postpartum pituitary necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996031"}
{"pmid": "20996032", "title": "A study of normal and abnormal menstrual function in the Auxiliary Territorial Service.", "content": "A study of normal and abnormal menstrual function in the Auxiliary Territorial Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996032"}
{"pmid": "20996033", "title": "Classification of the human pelvis, with a preliminary note on the evolution of the anthropoid or ultradolichopellic type of pelvis.", "content": "Classification of the human pelvis, with a preliminary note on the evolution of the anthropoid or ultradolichopellic type of pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996033"}
{"pmid": "20996034", "title": "A nutritional survey among pregnant women.", "content": "A nutritional survey among pregnant women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996034"}
{"pmid": "20996035", "title": "Haemoglobin values in female workers.", "content": "Haemoglobin values in female workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996035"}
{"pmid": "20996037", "title": "Residential rest during the antenatal period.", "content": "Residential rest during the antenatal period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996037"}
{"pmid": "20996038", "title": "Full-time secondary abdominal pregnancy with delivery of living child.", "content": "Full-time secondary abdominal pregnancy with delivery of living child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996038"}
{"pmid": "20996036", "title": "Calcium and phosphorus metabolism in pregnancy (a survey under war and post-war conditions).", "content": "Calcium and phosphorus metabolism in pregnancy (a survey under war and post-war conditions).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996036"}
{"pmid": "20996039", "title": "Some gynaecological aspects of referred pain.", "content": "Some gynaecological aspects of referred pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996039"}
{"pmid": "20996040", "title": "Investigation of the serum protein balance in normal and toxaemic pregnant women.", "content": "Investigation of the serum protein balance in normal and toxaemic pregnant women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996040"}
{"pmid": "20996041", "title": "Six cases of venous intravasation following intrauterine lipiodol injection.", "content": "Six cases of venous intravasation following intrauterine lipiodol injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996041"}
{"pmid": "20996044", "title": "Pulmonary tuberculosis and pregnancy.", "content": "Pulmonary tuberculosis and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996044"}
{"pmid": "20996043", "title": "Calcium and phosphorus metabolism in pregnancy (a survey under war and post-war conditions).", "content": "Calcium and phosphorus metabolism in pregnancy (a survey under war and post-war conditions).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996043"}
{"pmid": "20996045", "title": "The cause of prolapsus uteri in women in the light of perineal prolapse in mice.", "content": "The cause of prolapsus uteri in women in the light of perineal prolapse in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996045"}
{"pmid": "20996046", "title": "Planning a home; making a home; running a home.", "content": "Planning a home; making a home; running a home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996046"}
{"pmid": "20996042", "title": "Spinal analgesia for forceps delivery in abnormal labour.", "content": "Spinal analgesia for forceps delivery in abnormal labour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996042"}
{"pmid": "20996047", "title": "Marriage.", "content": "Marriage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996047"}
{"pmid": "20996048", "title": "Incidence of dental disease and the care of the teeth of expectant and nursing mothers and children under five years.", "content": "Incidence of dental disease and the care of the teeth of expectant and nursing mothers and children under five years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996048"}
{"pmid": "20996049", "title": "The care and treatment of the handicapped child.", "content": "The care and treatment of the handicapped child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996049"}
{"pmid": "20996051", "title": "Carcinoma of the esophagus.", "content": "Carcinoma of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996051"}
{"pmid": "20996050", "title": "Injuries of the chest.", "content": "Injuries of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996050"}
{"pmid": "20996052", "title": "Arterial hypertension.", "content": "Arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996052"}
{"pmid": "20996053", "title": "Observations on action of Myrica cerifera.", "content": "Observations on action of Myrica cerifera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996053"}
{"pmid": "20996054", "title": "Homeopathic philosophy.", "content": "Homeopathic philosophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996054"}
{"pmid": "20996055", "title": "Some ideas on the administrative organisation of the regional hospital boards.", "content": "Some ideas on the administrative organisation of the regional hospital boards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996055"}
{"pmid": "20996056", "title": "USE of activated DDT emulsion paints in the control of insect pests.", "content": "USE of activated DDT emulsion paints in the control of insect pests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996056"}
{"pmid": "20996057", "title": "Hospital planning; plan examples.", "content": "Hospital planning; plan examples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996057"}
{"pmid": "20996058", "title": "Hospital lifts.", "content": "Hospital lifts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996058"}
{"pmid": "20996059", "title": "Color and psychotherapy.", "content": "Color and psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996059"}
{"pmid": "20996062", "title": "Can doctors and hospitals get along?", "content": "Can doctors and hospitals get along?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996062"}
{"pmid": "20996061", "title": "Music is in tune with the art of healing.", "content": "Music is in tune with the art of healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996061"}
{"pmid": "20996060", "title": "Health centers under two roofs to serve the people of Cincinnati.", "content": "Health centers under two roofs to serve the people of Cincinnati.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996060"}
{"pmid": "20996064", "title": "Fire costs more than prevention.", "content": "Fire costs more than prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996064"}
{"pmid": "20996063", "title": "The case of dietitian versus hospital field.", "content": "The case of dietitian versus hospital field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996063"}
{"pmid": "20996065", "title": "The modern mental hospital must be planned around the patient and integrated with the community.", "content": "The modern mental hospital must be planned around the patient and integrated with the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996065"}
{"pmid": "20996066", "title": "Sample meals show dietary deficiencies in tuberculosis hospitals.", "content": "Sample meals show dietary deficiencies in tuberculosis hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996066"}
{"pmid": "20996067", "title": "Solving the incomplete records problem.", "content": "Solving the incomplete records problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996067"}
{"pmid": "20996068", "title": "General duty nursing in the hospital.", "content": "General duty nursing in the hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996068"}
{"pmid": "20996069", "title": "The care of the veteran.", "content": "The care of the veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996069"}
{"pmid": "20996070", "title": "Occupational medicine; retrospect and prospect.", "content": "Occupational medicine; retrospect and prospect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996070"}
{"pmid": "20996072", "title": "Perforating ocular injuries.", "content": "Perforating ocular injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996072"}
{"pmid": "20996071", "title": "The industrial environment.", "content": "The industrial environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996071"}
{"pmid": "20996073", "title": "SAFETY engineering unit of the State of Michigan Department of Labor and Industry.", "content": "SAFETY engineering unit of the State of Michigan Department of Labor and Industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996073"}
{"pmid": "20996074", "title": "WORKER and his job; symposium at the Annual Meeting of the Western Association of Industrial Physicians and Surgeons, San Francisco, June 30, 1946.", "content": "WORKER and his job; symposium at the Annual Meeting of the Western Association of Industrial Physicians and Surgeons, San Francisco, June 30, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996074"}
{"pmid": "20996076", "title": "The pneumoconioses.", "content": "The pneumoconioses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996076"}
{"pmid": "20996075", "title": "The utilization of aluminum in the prevention and treatment of silicosis.", "content": "The utilization of aluminum in the prevention and treatment of silicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996075"}
{"pmid": "20996077", "title": "Bernardini Ramazzini, his life, deeds and book.", "content": "Bernardini Ramazzini, his life, deeds and book.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996077"}
{"pmid": "20996078", "title": "Industrial Health Conference; highlights of proceedings of annual meetings of industrial physicians and surgeons, hygienists, nurses, and dentists, Chicago, April 7-14, 1946.", "content": "Industrial Health Conference; highlights of proceedings of annual meetings of industrial physicians and surgeons, hygienists, nurses, and dentists, Chicago, April 7-14, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996078"}
{"pmid": "20996079", "title": "Administrative aspects of mass radiography.", "content": "Administrative aspects of mass radiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996079"}
{"pmid": "20996080", "title": "Toxicology of newer metals.", "content": "Toxicology of newer metals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996080"}
{"pmid": "20996081", "title": "Decentralization of official industrial hygiene activities.", "content": "Decentralization of official industrial hygiene activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996081"}
{"pmid": "20996082", "title": "Determining the concentration of mercury in the air.", "content": "Determining the concentration of mercury in the air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996082"}
{"pmid": "20996083", "title": "New developments in commercial instruments of air analysis.", "content": "New developments in commercial instruments of air analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996083"}
{"pmid": "20996084", "title": "Mercury vapor hazards in certain chemical laboratories.", "content": "Mercury vapor hazards in certain chemical laboratories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996084"}
{"pmid": "20996085", "title": "The 31st annual meeting of the American Association of Industrial Physicians and Surgeons also marks its first peacetime conference after World War II.", "content": "The 31st annual meeting of the American Association of Industrial Physicians and Surgeons also marks its first peacetime conference after World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996085"}
{"pmid": "20996086", "title": "Presidential address of the American Industrial Hygiene Association.", "content": "Presidential address of the American Industrial Hygiene Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996086"}
{"pmid": "20996087", "title": "Industrial dermatoses.", "content": "Industrial dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996087"}
{"pmid": "20996088", "title": "Toxicity and potential dangers of ethylene dichloride.", "content": "Toxicity and potential dangers of ethylene dichloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996088"}
{"pmid": "20996089", "title": "A comparison of the physiological effects of monomethylaniline and xylidene.", "content": "A comparison of the physiological effects of monomethylaniline and xylidene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996089"}
{"pmid": "20996090", "title": "The dispersion and control of triethylene glycol vapors for aerial disinfection.", "content": "The dispersion and control of triethylene glycol vapors for aerial disinfection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996090"}
{"pmid": "20996091", "title": "Prophylaxis against mercury-induced ventricular fibrillation.", "content": "Prophylaxis against mercury-induced ventricular fibrillation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996091"}
{"pmid": "20996092", "title": "Health records in small plants.", "content": "Health records in small plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996092"}
{"pmid": "20996093", "title": "Pre-payment as a private enterprise.", "content": "Pre-payment as a private enterprise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996093"}
{"pmid": "20996094", "title": "Onycholysis in fur workers.", "content": "Onycholysis in fur workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996094"}
{"pmid": "20996096", "title": "Effects of total pancreatectomy in a patient with diabetes.", "content": "Effects of total pancreatectomy in a patient with diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996096"}
{"pmid": "20996095", "title": "The anticonvulsant properties of tridione.", "content": "The anticonvulsant properties of tridione.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996095"}
{"pmid": "20996097", "title": "Clearance of inulin, diodrast, chloride and phosphate under mercurial diuresis; intensive study of a patient in severe cardiac failure.", "content": "Clearance of inulin, diodrast, chloride and phosphate under mercurial diuresis; intensive study of a patient in severe cardiac failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996097"}
{"pmid": "20996098", "title": "Chrysotherapy in rheumatoid arthritis.", "content": "Chrysotherapy in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996098"}
{"pmid": "20996100", "title": "Penicillin aerosol and negative pressure in the treatment of sinusitis.", "content": "Penicillin aerosol and negative pressure in the treatment of sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996100"}
{"pmid": "20996099", "title": "The diagnosis and treatment of diseases of the anorectum.", "content": "The diagnosis and treatment of diseases of the anorectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996099"}
{"pmid": "20996101", "title": "Treatment of coronary artery disease.", "content": "Treatment of coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996101"}
{"pmid": "20996102", "title": "Isolation of virulent Treponema pallidum from human aorta thirty-two hours after death from cardiovascular syphilis.", "content": "Isolation of virulent Treponema pallidum from human aorta thirty-two hours after death from cardiovascular syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996102"}
{"pmid": "20996103", "title": "Acute monocytic leukemia.", "content": "Acute monocytic leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996103"}
{"pmid": "20996104", "title": "MECHANISMS of edema formation.", "content": "MECHANISMS of edema formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996104"}
{"pmid": "20996105", "title": "Sudden death in obstetrics.", "content": "Sudden death in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996105"}
{"pmid": "20996106", "title": "Evaluation of the changes in gangrene of the extremities.", "content": "Evaluation of the changes in gangrene of the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996106"}
{"pmid": "20996107", "title": "The scalenus anticus syndrome.", "content": "The scalenus anticus syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996107"}
{"pmid": "20996108", "title": "Pediatric parenteral fluids.", "content": "Pediatric parenteral fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996108"}
{"pmid": "20996109", "title": "The effect of tobacco smoke on Kahn and Hinton reactions.", "content": "The effect of tobacco smoke on Kahn and Hinton reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996109"}
{"pmid": "20996110", "title": "Selling medical plans to the doctors.", "content": "Selling medical plans to the doctors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996110"}
{"pmid": "20996111", "title": "HEALTH of children in wartime day nurseries.", "content": "HEALTH of children in wartime day nurseries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996111"}
{"pmid": "20996112", "title": "The aftermath of perforated peptic ulcer.", "content": "The aftermath of perforated peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996112"}
{"pmid": "20996113", "title": "Meningitis due to a penicillin-sensitive, sulphonamide-insensitive Pittman b strain of H. influenzae; recovery.", "content": "Meningitis due to a penicillin-sensitive, sulphonamide-insensitive Pittman b strain of H. influenzae; recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996113"}
{"pmid": "20996114", "title": "Acute enteritis in subtropical climates.", "content": "Acute enteritis in subtropical climates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996114"}
{"pmid": "20996115", "title": "Overdosage with bromides.", "content": "Overdosage with bromides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996115"}
{"pmid": "20996116", "title": "Laryngeal foreign body.", "content": "Laryngeal foreign body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996116"}
{"pmid": "20996117", "title": "Lingual-nerve block for calculi in Wharton's duct.", "content": "Lingual-nerve block for calculi in Wharton's duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996117"}
{"pmid": "20996118", "title": "Chemotherapy of tuberculosis.", "content": "Chemotherapy of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996118"}
{"pmid": "20996119", "title": "Amenorrhoea during internment.", "content": "Amenorrhoea during internment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996119"}
{"pmid": "20996120", "title": "Rheumatic fever.", "content": "Rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996120"}
{"pmid": "20996121", "title": "Tobacco and ulcer dyspepsia.", "content": "Tobacco and ulcer dyspepsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996121"}
{"pmid": "20996122", "title": "Electro-convulsion therapy in 301 patients in a general hospital, with special reference to selection of cases and response to treatment.", "content": "Electro-convulsion therapy in 301 patients in a general hospital, with special reference to selection of cases and response to treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996122"}
{"pmid": "20996123", "title": "Technique for the use of d-tubocurarine chloride with balanced anaesthesia.", "content": "Technique for the use of d-tubocurarine chloride with balanced anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996123"}
{"pmid": "20996124", "title": "Some uses of thrombin in the surgery of the ear, nose, and throat.", "content": "Some uses of thrombin in the surgery of the ear, nose, and throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996124"}
{"pmid": "20996125", "title": "Staphylococcal spinal osteomyelitis with acute extradural abscess.", "content": "Staphylococcal spinal osteomyelitis with acute extradural abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996125"}
{"pmid": "20996127", "title": "Reiter's disease.", "content": "Reiter's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996127"}
{"pmid": "20996126", "title": "Plant dermatitis in the Bahamas.", "content": "Plant dermatitis in the Bahamas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996126"}
{"pmid": "20996128", "title": "Maternal and infant care.", "content": "Maternal and infant care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996128"}
{"pmid": "20996129", "title": "Cleveland birth trends.", "content": "Cleveland birth trends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996129"}
{"pmid": "20996130", "title": "Vaccination study of junior high school pupils.", "content": "Vaccination study of junior high school pupils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996130"}
{"pmid": "20996132", "title": "The early recognition of uterine cancer.", "content": "The early recognition of uterine cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996132"}
{"pmid": "20996131", "title": "The present status of thiouracil.", "content": "The present status of thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996131"}
{"pmid": "20996133", "title": "Observations on the surgical relief of pain in cancer.", "content": "Observations on the surgical relief of pain in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996133"}
{"pmid": "20996135", "title": "Paraplegia following war.", "content": "Paraplegia following war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996135"}
{"pmid": "20996134", "title": "Penicillin in pyoderma.", "content": "Penicillin in pyoderma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996134"}
{"pmid": "20996136", "title": "Pruritus ani.", "content": "Pruritus ani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996136"}
{"pmid": "20996138", "title": "The nasal mechanisms; their maintenance and repair.", "content": "The nasal mechanisms; their maintenance and repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996138"}
{"pmid": "20996137", "title": "Ureteritis cystica and some renal anomalies.", "content": "Ureteritis cystica and some renal anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996137"}
{"pmid": "20996139", "title": "Pelvic pain.", "content": "Pelvic pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996139"}
{"pmid": "20996140", "title": "Chronic or recurrent diarrhoea.", "content": "Chronic or recurrent diarrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996140"}
{"pmid": "20996141", "title": "Amoebiasis.", "content": "Amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996141"}
{"pmid": "20996143", "title": "Foreign body in the oesophagus.", "content": "Foreign body in the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996143"}
{"pmid": "20996142", "title": "The significance of the sedimentation rate to the general practitioner.", "content": "The significance of the sedimentation rate to the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996142"}
{"pmid": "20996144", "title": "Calcaneoscaphoid bar.", "content": "Calcaneoscaphoid bar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996144"}
{"pmid": "20996145", "title": "Severe, delayed procaine poisoning.", "content": "Severe, delayed procaine poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996145"}
{"pmid": "20996146", "title": "Primary splenic neutropenia.", "content": "Primary splenic neutropenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996146"}
{"pmid": "20996147", "title": "Care of the unmarried mother and her child.", "content": "Care of the unmarried mother and her child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996147"}
{"pmid": "20996148", "title": "Artificial pneumoperitoneum for the diagnosis of subdiaphragmatic abscess.", "content": "Artificial pneumoperitoneum for the diagnosis of subdiaphragmatic abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996148"}
{"pmid": "20996149", "title": "Delta; a problem in authorship.", "content": "Delta; a problem in authorship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996149"}
{"pmid": "20996150", "title": "Persistent problems of pneumonia.", "content": "Persistent problems of pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996150"}
{"pmid": "20996151", "title": "Pollution factors in urban atmospheres.", "content": "Pollution factors in urban atmospheres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996151"}
{"pmid": "20996152", "title": "Mycotic aneurysm of the aorta, chronic suppurative osteomyelitis and pyarthrosis, psoas abscess and chronic suppurative cellulitis; organizing sero-fibrinous pericarditis; miliary abscesses of kidneys and spleen (Staphylococcus aureus septicemia).", "content": "Mycotic aneurysm of the aorta, chronic suppurative osteomyelitis and pyarthrosis, psoas abscess and chronic suppurative cellulitis; organizing sero-fibrinous pericarditis; miliary abscesses of kidneys and spleen (Staphylococcus aureus septicemia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996152"}
{"pmid": "20996153", "title": "Paraplegia following war.", "content": "Paraplegia following war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996153"}
{"pmid": "20996155", "title": "The steam locomotive and atmospheric pollution.", "content": "The steam locomotive and atmospheric pollution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996155"}
{"pmid": "20996154", "title": "The relationship of smoke to pneumonia and other infections of the respiratory system.", "content": "The relationship of smoke to pneumonia and other infections of the respiratory system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996154"}
{"pmid": "20996156", "title": "Rabies encephalitis.", "content": "Rabies encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996156"}
{"pmid": "20996161", "title": "Federal medicine and what it means to the patient.", "content": "Federal medicine and what it means to the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996161"}
{"pmid": "20996162", "title": "Federal medicine and the doctor.", "content": "Federal medicine and the doctor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996162"}
{"pmid": "20996163", "title": "Ligation of the ductus arteriosus.", "content": "Ligation of the ductus arteriosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996163"}
{"pmid": "20996165", "title": "Tuberculosis under a national health service.", "content": "Tuberculosis under a national health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996165"}
{"pmid": "20996164", "title": "Patent ductus arteriosus and its surgical treatment.", "content": "Patent ductus arteriosus and its surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996164"}
{"pmid": "20996157", "title": "The clinical application of the anatomy of the abdomen.", "content": "The clinical application of the anatomy of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996157"}
{"pmid": "20996166", "title": "The value of vitamin A estimation in blood.", "content": "The value of vitamin A estimation in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996166"}
{"pmid": "20996167", "title": "The effect of arteriovenous aneurysms on blood volume and blood picture.", "content": "The effect of arteriovenous aneurysms on blood volume and blood picture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996167"}
{"pmid": "20996168", "title": "Curare in anaesthesia.", "content": "Curare in anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996168"}
{"pmid": "20996169", "title": "Paroxysmal ventricular tachycardia.", "content": "Paroxysmal ventricular tachycardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996169"}
{"pmid": "20996170", "title": "[Osteoporosis in thyrotoxicosis].", "content": "[Osteoporosis in thyrotoxicosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996170"}
{"pmid": "20996160", "title": "A case of carcinoma of vulva secondary to a primary growth in the breast.", "content": "A case of carcinoma of vulva secondary to a primary growth in the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996160"}
{"pmid": "20996158", "title": "Congenital heart disease.", "content": "Congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996158"}
{"pmid": "20996159", "title": "The treatment of erythroblastosis foetalis.", "content": "The treatment of erythroblastosis foetalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996159"}
{"pmid": "20996171", "title": "A case of post-haemorrhagic blindness.", "content": "A case of post-haemorrhagic blindness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996171"}
{"pmid": "20996172", "title": "A tour of the United States plastic surgery centres.", "content": "A tour of the United States plastic surgery centres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996172"}
{"pmid": "20996173", "title": "Headache.", "content": "Headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996173"}
{"pmid": "20996174", "title": "Some impressions of Greek surgery.", "content": "Some impressions of Greek surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996174"}
{"pmid": "20996175", "title": "Constructive medicine and industry.", "content": "Constructive medicine and industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996175"}
{"pmid": "20996176", "title": "Control of ringworm of the scalp among school children.", "content": "Control of ringworm of the scalp among school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996176"}
{"pmid": "20996177", "title": "Ringworm of the scalp; clinical data on recent cases; experiences with local endocrine therapy.", "content": "Ringworm of the scalp; clinical data on recent cases; experiences with local endocrine therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996177"}
{"pmid": "20996178", "title": "Tinea capitis; its treatment with special iodine and dilute acetic acid.", "content": "Tinea capitis; its treatment with special iodine and dilute acetic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996178"}
{"pmid": "20996179", "title": "Local treatment of tinea capitis.", "content": "Local treatment of tinea capitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996179"}
{"pmid": "20996181", "title": "Generalized angioneurotic edema due to penicillin inhalations treated with benadryl.", "content": "Generalized angioneurotic edema due to penicillin inhalations treated with benadryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996181"}
{"pmid": "20996180", "title": "Agranulocytosis from thiouracil; occurring during prophylactic treatment with folic acid.", "content": "Agranulocytosis from thiouracil; occurring during prophylactic treatment with folic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996180"}
{"pmid": "20996182", "title": "The long-range care in cases of myocardial infarction and angina pectoris.", "content": "The long-range care in cases of myocardial infarction and angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996182"}
{"pmid": "20996183", "title": "Acute surgical infections of the kidney.", "content": "Acute surgical infections of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996183"}
{"pmid": "20996184", "title": "The use of the nasopharyngeal radium applicator.", "content": "The use of the nasopharyngeal radium applicator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996184"}
{"pmid": "20996185", "title": "Tumors of the nose and throat.", "content": "Tumors of the nose and throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996185"}
{"pmid": "20996186", "title": "Practical application of the Rh factor in congenital hemolytic anemia of the newborn (erythroblastosis fetalis), habitual abortion, and blood transfusions.", "content": "Practical application of the Rh factor in congenital hemolytic anemia of the newborn (erythroblastosis fetalis), habitual abortion, and blood transfusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996186"}
{"pmid": "20996187", "title": "Reconstructive surgery following treatment of osteomyelitis by saucerization and early skin grafting.", "content": "Reconstructive surgery following treatment of osteomyelitis by saucerization and early skin grafting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996187"}
{"pmid": "20996188", "title": "Anesthetic progress.", "content": "Anesthetic progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996188"}
{"pmid": "20996189", "title": "The ambulatory treatment of phlebitis.", "content": "The ambulatory treatment of phlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996189"}
{"pmid": "20996190", "title": "Thiourea and its derivative thiouracil as a goitrogen.", "content": "Thiourea and its derivative thiouracil as a goitrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996190"}
{"pmid": "20996191", "title": "Political medicine as viewed by one of Connecticut's psychiatrists.", "content": "Political medicine as viewed by one of Connecticut's psychiatrists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996191"}
{"pmid": "20996193", "title": "Anopheline mosquitoes in Montana.", "content": "Anopheline mosquitoes in Montana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996193"}
{"pmid": "20996192", "title": "Sulfonamides and antibiotics in the prevention and treatment of infectious diseases.", "content": "Sulfonamides and antibiotics in the prevention and treatment of infectious diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996192"}
{"pmid": "20996194", "title": "Regional enteritis; a report of a case complicating pregnancy with a review of the literature.", "content": "Regional enteritis; a report of a case complicating pregnancy with a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996194"}
{"pmid": "20996195", "title": "In tussusception.", "content": "In tussusception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996195"}
{"pmid": "20996197", "title": "Vitamin A and skin disease.", "content": "Vitamin A and skin disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996197"}
{"pmid": "20996196", "title": "Serious psychiatric disability among British officers in India.", "content": "Serious psychiatric disability among British officers in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996196"}
{"pmid": "20996198", "title": "Stabilisation of penicillin solutions with phosphate.", "content": "Stabilisation of penicillin solutions with phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996198"}
{"pmid": "20996199", "title": "A syndrome simulating acute abdominal disease.", "content": "A syndrome simulating acute abdominal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996199"}
{"pmid": "20996200", "title": "Sporotrichosis resembling diphtheria.", "content": "Sporotrichosis resembling diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996200"}
{"pmid": "20996201", "title": "Peptic ulcer treated with gastric and intestinal extracts.", "content": "Peptic ulcer treated with gastric and intestinal extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996201"}
{"pmid": "20996202", "title": "JOURNALS of the British Medical Association.", "content": "JOURNALS of the British Medical Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996202"}
{"pmid": "20996203", "title": "Advertising patent medicines.", "content": "Advertising patent medicines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996203"}
{"pmid": "20996204", "title": "Smallpox and vaccination.", "content": "Smallpox and vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996204"}
{"pmid": "20996205", "title": "Prospects in poliomyelitis.", "content": "Prospects in poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996205"}
{"pmid": "20996206", "title": "Myth and mumpsimus.", "content": "Myth and mumpsimus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996206"}
{"pmid": "20996207", "title": "Medical photography; a review.", "content": "Medical photography; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996207"}
{"pmid": "20996208", "title": "The hospital photographic department.", "content": "The hospital photographic department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996208"}
{"pmid": "20996210", "title": "TEACHING of anatomy.", "content": "TEACHING of anatomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996210"}
{"pmid": "20996209", "title": "Anatomical models in teaching.", "content": "Anatomical models in teaching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996209"}
{"pmid": "20996211", "title": "Strasbourg and Manchester, a proposed liaison.", "content": "Strasbourg and Manchester, a proposed liaison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996211"}
{"pmid": "20996212", "title": "Recent trends in infant feeding.", "content": "Recent trends in infant feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996212"}
{"pmid": "20996213", "title": "Thiouracil in the treatment of hyperthyroidism.", "content": "Thiouracil in the treatment of hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996213"}
{"pmid": "20996214", "title": "Treatment of carcinoma of the prostate.", "content": "Treatment of carcinoma of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996214"}
{"pmid": "20996215", "title": "An outline of the care of the paraplegic patient.", "content": "An outline of the care of the paraplegic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996215"}
{"pmid": "20996216", "title": "ESTABLISHMENT of a medical research division.", "content": "ESTABLISHMENT of a medical research division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996216"}
{"pmid": "20996217", "title": "Recognition of heart disease; differential diagnosis of left ventricular enlargement.", "content": "Recognition of heart disease; differential diagnosis of left ventricular enlargement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996217"}
{"pmid": "20996218", "title": "Factors in child personality development.", "content": "Factors in child personality development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996218"}
{"pmid": "20996219", "title": "Thrombocytopenia complicating rubella.", "content": "Thrombocytopenia complicating rubella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996219"}
{"pmid": "20996220", "title": "Treatment of purpura.", "content": "Treatment of purpura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996220"}
{"pmid": "20996221", "title": "Screening of cancer.", "content": "Screening of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996221"}
{"pmid": "20996222", "title": "Prognosis and treatment of influenzal meningitis.", "content": "Prognosis and treatment of influenzal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996222"}
{"pmid": "20996223", "title": "The reticulo-endothelial system.", "content": "The reticulo-endothelial system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996223"}
{"pmid": "20996224", "title": "Malaria in the South-West Pacific, with special reference to its chemo-therapeutic control.", "content": "Malaria in the South-West Pacific, with special reference to its chemo-therapeutic control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996224"}
{"pmid": "20996225", "title": "Deficiency diseases.", "content": "Deficiency diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996225"}
{"pmid": "20996226", "title": "Patent ductus arteriosus.", "content": "Patent ductus arteriosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996226"}
{"pmid": "20996227", "title": "Motor mechanisms in the central nervous system.", "content": "Motor mechanisms in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996227"}
{"pmid": "20996228", "title": "Seasonal variations in the ascorbic acid content of the Australian diet.", "content": "Seasonal variations in the ascorbic acid content of the Australian diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996228"}
{"pmid": "20996229", "title": "The basis of post-operative treatment in appendicitis and peritonitis; folklore or physiology?", "content": "The basis of post-operative treatment in appendicitis and peritonitis; folklore or physiology?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996229"}
{"pmid": "20996230", "title": "The use of gamma globulin in the prophylaxis of measles.", "content": "The use of gamma globulin in the prophylaxis of measles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996230"}
{"pmid": "20996231", "title": "The insertion of the transfusion needle made easy.", "content": "The insertion of the transfusion needle made easy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996231"}
{"pmid": "20996232", "title": "Diagnosis of anxiety neurosis.", "content": "Diagnosis of anxiety neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996232"}
{"pmid": "20996233", "title": "Studies of maternal and infantile blood factor relationships.", "content": "Studies of maternal and infantile blood factor relationships.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996233"}
{"pmid": "20996234", "title": "Tuberculosis in pregnancy.", "content": "Tuberculosis in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996234"}
{"pmid": "20996235", "title": "Pulmonary tuberculosis in pregnancy.", "content": "Pulmonary tuberculosis in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996235"}
{"pmid": "20996236", "title": "The burning feet syndrome; observations of cases among prisoners of war in Manchuria.", "content": "The burning feet syndrome; observations of cases among prisoners of war in Manchuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996236"}
{"pmid": "20996237", "title": "Dangerous blood donors.", "content": "Dangerous blood donors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996237"}
{"pmid": "20996238", "title": "Tuberculosis and pregnancy.", "content": "Tuberculosis and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996238"}
{"pmid": "20996239", "title": "Malaria in the South-West Pacific.", "content": "Malaria in the South-West Pacific.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996239"}
{"pmid": "20996241", "title": "North Queensland tick typhus; a comparative study of the rickettsia with that of murine typhus.", "content": "North Queensland tick typhus; a comparative study of the rickettsia with that of murine typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996241"}
{"pmid": "20996240", "title": "Tick typhus in North Queensland.", "content": "Tick typhus in North Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996240"}
{"pmid": "20996242", "title": "North Queensland tick typhus; studies of the aetiological agent and its relation to other rickettsial diseases.", "content": "North Queensland tick typhus; studies of the aetiological agent and its relation to other rickettsial diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996242"}
{"pmid": "20996243", "title": "Alcohol.", "content": "Alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996243"}
{"pmid": "20996244", "title": "Alcoholism.", "content": "Alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996244"}
{"pmid": "20996245", "title": "Reproductions of radiographs by solarization.", "content": "Reproductions of radiographs by solarization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996245"}
{"pmid": "20996246", "title": "Associated carcinoma and tuberculosis in one kidney.", "content": "Associated carcinoma and tuberculosis in one kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996246"}
{"pmid": "20996247", "title": "Malaria in the South-West Pacific; additional facts about malaria control in the Australian military forces.", "content": "Malaria in the South-West Pacific; additional facts about malaria control in the Australian military forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996247"}
{"pmid": "20996248", "title": "The need for continued supervision after operation for thyrotoxicosis.", "content": "The need for continued supervision after operation for thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996248"}
{"pmid": "20996249", "title": "Impulsive outbreaks in children.", "content": "Impulsive outbreaks in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996249"}
{"pmid": "20996250", "title": "A case of local reaction following the administration of penicillin in beeswax and oil.", "content": "A case of local reaction following the administration of penicillin in beeswax and oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996250"}
{"pmid": "20996252", "title": "Bone absorptive changes in leprosy.", "content": "Bone absorptive changes in leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996252"}
{"pmid": "20996251", "title": "Hypoparathyroidal changes of the teeth in adults.", "content": "Hypoparathyroidal changes of the teeth in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996251"}
{"pmid": "20996253", "title": "The common atomizer as an efficient agent for penicillin inhalation, in bacterial complications of nasal and bronchial allergy.", "content": "The common atomizer as an efficient agent for penicillin inhalation, in bacterial complications of nasal and bronchial allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996253"}
{"pmid": "20996254", "title": "Poetic justice and its unconscious background.", "content": "Poetic justice and its unconscious background.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996254"}
{"pmid": "20996255", "title": "The bacterium's point of view.", "content": "The bacterium's point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996255"}
{"pmid": "20996256", "title": "SPECIALIST versus the general practitioner of medicine.", "content": "SPECIALIST versus the general practitioner of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996256"}
{"pmid": "20996257", "title": "Acute generalized miliary tuberculosis in adults.", "content": "Acute generalized miliary tuberculosis in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996257"}
{"pmid": "20996258", "title": "The late results of femoral thrombophlebitis and their treatment.", "content": "The late results of femoral thrombophlebitis and their treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996258"}
{"pmid": "20996259", "title": "Dextrocardia and bronchiectasis, a review of the literature and a report of two cases.", "content": "Dextrocardia and bronchiectasis, a review of the literature and a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996259"}
{"pmid": "20996260", "title": "Tuberculosis of bronchus.", "content": "Tuberculosis of bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996260"}
{"pmid": "20996261", "title": "Abdominal pregnancy.", "content": "Abdominal pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996261"}
{"pmid": "20996262", "title": "Graduates of nonapproved medical schools.", "content": "Graduates of nonapproved medical schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996262"}
{"pmid": "20996263", "title": "The treatment of subacute bacterial endocarditis with penicillin in peanut oil and beeswax.", "content": "The treatment of subacute bacterial endocarditis with penicillin in peanut oil and beeswax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996263"}
{"pmid": "20996264", "title": "Statistics of diabetes.", "content": "Statistics of diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996264"}
{"pmid": "20996265", "title": "Anesthesia for radical mastectomy with intravenous pentothal sodium and intercostal nerve block.", "content": "Anesthesia for radical mastectomy with intravenous pentothal sodium and intercostal nerve block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996265"}
{"pmid": "20996266", "title": "Active immunization.", "content": "Active immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996266"}
{"pmid": "20996267", "title": "Acute and chronic cholecystitis, with hydrops, producing partial obstruction of cecum.", "content": "Acute and chronic cholecystitis, with hydrops, producing partial obstruction of cecum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996267"}
{"pmid": "20996269", "title": "SIGNING out of tuberculous patients.", "content": "SIGNING out of tuberculous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996269"}
{"pmid": "20996268", "title": "Strangulated small intestine due to an adhesive band.", "content": "Strangulated small intestine due to an adhesive band.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996268"}
{"pmid": "20996270", "title": "Cesarean section versus test of labor.", "content": "Cesarean section versus test of labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996270"}
{"pmid": "20996271", "title": "The surgical treatment of hypertension.", "content": "The surgical treatment of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996271"}
{"pmid": "20996272", "title": "Orthostatic hypotension; its occurrence in dermatology.", "content": "Orthostatic hypotension; its occurrence in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996272"}
{"pmid": "20996274", "title": "165 acute combined wounds of the thorax and abdomen.", "content": "165 acute combined wounds of the thorax and abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996274"}
{"pmid": "20996273", "title": "Simultaneous traumatic dislocation of both the right hip and the right knee joint; a case report.", "content": "Simultaneous traumatic dislocation of both the right hip and the right knee joint; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996273"}
{"pmid": "20996275", "title": "Demonstration of tubercle bacilli; survey of methods used in Ohio and recommended procedures.", "content": "Demonstration of tubercle bacilli; survey of methods used in Ohio and recommended procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996275"}
{"pmid": "20996277", "title": "Laryngeal stridor in children.", "content": "Laryngeal stridor in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996277"}
{"pmid": "20996278", "title": "An evaluation of oral penicillin with reference to the treatment of urinary tract infections.", "content": "An evaluation of oral penicillin with reference to the treatment of urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996278"}
{"pmid": "20996276", "title": "A report of 13,113 complete physical examinations of Philadelphia public school pupils, school years 1943 to 1945.", "content": "A report of 13,113 complete physical examinations of Philadelphia public school pupils, school years 1943 to 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996276"}
{"pmid": "20996279", "title": "Gastroduodenal ulcer.", "content": "Gastroduodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996279"}
{"pmid": "20996280", "title": "Why neurotics: veteran problem.", "content": "Why neurotics: veteran problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996280"}
{"pmid": "20996281", "title": "Frigidity in the female.", "content": "Frigidity in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996281"}
{"pmid": "20996283", "title": "Implementation of the medical profession's program at the State level.", "content": "Implementation of the medical profession's program at the State level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996283"}
{"pmid": "20996282", "title": "Excision of pilonidal cyst and sinus with primary union; using local infiltration and topical application of penicillin solution.", "content": "Excision of pilonidal cyst and sinus with primary union; using local infiltration and topical application of penicillin solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996282"}
{"pmid": "20996284", "title": "Present economic trends and the State Medical Society.", "content": "Present economic trends and the State Medical Society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996284"}
{"pmid": "20996285", "title": "Presidential address [group medicine].", "content": "Presidential address [group medicine].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996285"}
{"pmid": "20996286", "title": "Severe rheumatic heart disease in children.", "content": "Severe rheumatic heart disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996286"}
{"pmid": "20996287", "title": "Management of the neuropsychiatric patient; hospitalized or ambulatory.", "content": "Management of the neuropsychiatric patient; hospitalized or ambulatory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996287"}
{"pmid": "20996288", "title": "Intramuscular urography.", "content": "Intramuscular urography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996288"}
{"pmid": "20996289", "title": "A few factors in lid repair.", "content": "A few factors in lid repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996289"}
{"pmid": "20996290", "title": "Uretero-intestinal transplantation.", "content": "Uretero-intestinal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996290"}
{"pmid": "20996291", "title": "The significance of concordant inverted initial ventricular deflections in the electrocardiogram of patients with pulmonary tuberculosis.", "content": "The significance of concordant inverted initial ventricular deflections in the electrocardiogram of patients with pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996291"}
{"pmid": "20996292", "title": "Pulmonary mechanism for breath sounds.", "content": "Pulmonary mechanism for breath sounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996292"}
{"pmid": "20996293", "title": "Pathogenesis and prognosis of renal tuberculosis.", "content": "Pathogenesis and prognosis of renal tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996293"}
{"pmid": "20996294", "title": "Systematic reactions to the intravenous administration of congo red.", "content": "Systematic reactions to the intravenous administration of congo red.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996294"}
{"pmid": "20996295", "title": "The capacity of the lungs as conceived by John Hutchinson a century ago.", "content": "The capacity of the lungs as conceived by John Hutchinson a century ago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996295"}
{"pmid": "20996296", "title": "The primary infection of tuberculosis (a hazard).", "content": "The primary infection of tuberculosis (a hazard).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996296"}
{"pmid": "20996297", "title": "Extrapulmonary tuberculosis.", "content": "Extrapulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996297"}
{"pmid": "20996298", "title": "Theca-lutein cysts associated with hydatidiform mole.", "content": "Theca-lutein cysts associated with hydatidiform mole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996298"}
{"pmid": "20996299", "title": "Syphilitic stricture of the oesophagus.", "content": "Syphilitic stricture of the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996299"}
{"pmid": "20996300", "title": "The need for a new penological outlook in South Africa.", "content": "The need for a new penological outlook in South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996300"}
{"pmid": "20996301", "title": "An epidemiological survey of an outbreak of typhoid in the districts of Umtata, Mqanduli and Engcoba.", "content": "An epidemiological survey of an outbreak of typhoid in the districts of Umtata, Mqanduli and Engcoba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996301"}
{"pmid": "20996302", "title": "Fenestration and early hearing improvement.", "content": "Fenestration and early hearing improvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996302"}
{"pmid": "20996303", "title": "Thyrotoxicosis by myasthenia gravis.", "content": "Thyrotoxicosis by myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996303"}
{"pmid": "20996304", "title": "The restless infant.", "content": "The restless infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996304"}
{"pmid": "20996305", "title": "Manual acroparaesthesia.", "content": "Manual acroparaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996305"}
{"pmid": "20996307", "title": "A new arsenical in the treatment of syphilis.", "content": "A new arsenical in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996307"}
{"pmid": "20996306", "title": "Food yeast in the feeding of infants; its use in cases of mild diarrhoea.", "content": "Food yeast in the feeding of infants; its use in cases of mild diarrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996306"}
{"pmid": "20996308", "title": "Acroparaesthesia cruropedalis.", "content": "Acroparaesthesia cruropedalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996308"}
{"pmid": "20996309", "title": "Curare.", "content": "Curare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996309"}
{"pmid": "20996310", "title": "Intensive treatment of schistosomiasis.", "content": "Intensive treatment of schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996310"}
{"pmid": "20996312", "title": "PENICILLIN inhalation.", "content": "PENICILLIN inhalation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996312"}
{"pmid": "20996311", "title": "A case of recovery of a biliary pulmonary fistula.", "content": "A case of recovery of a biliary pulmonary fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996311"}
{"pmid": "20996313", "title": "Case of malignant bone tumour.", "content": "Case of malignant bone tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996313"}
{"pmid": "20996314", "title": "Case of transthoracic splenectomy.", "content": "Case of transthoracic splenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996314"}
{"pmid": "20996317", "title": "Indian fakirs.", "content": "Indian fakirs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996317"}
{"pmid": "20996318", "title": "Two cases of intravesical foreign bodies.", "content": "Two cases of intravesical foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996318"}
{"pmid": "20996319", "title": "A case of Hodgkin's disease with spinal cord involvement.", "content": "A case of Hodgkin's disease with spinal cord involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996319"}
{"pmid": "20996320", "title": "A county hospital; the relationships with rural and urban hospitals.", "content": "A county hospital; the relationships with rural and urban hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996320"}
{"pmid": "20996321", "title": "Medical problems of today.", "content": "Medical problems of today.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996321"}
{"pmid": "20996322", "title": "Hospital bed shortages.", "content": "Hospital bed shortages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996322"}
{"pmid": "20996323", "title": "NIGHT vision training and testing.", "content": "NIGHT vision training and testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996323"}
{"pmid": "20996324", "title": "BACTERIOSTATIC fabrics.", "content": "BACTERIOSTATIC fabrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996324"}
{"pmid": "20996325", "title": "FOOT problems in the Army.", "content": "FOOT problems in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996325"}
{"pmid": "20996326", "title": "MOTION sickness remedies.", "content": "MOTION sickness remedies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996326"}
{"pmid": "20996327", "title": "Prophylactic selection of Indian troops.", "content": "Prophylactic selection of Indian troops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996327"}
{"pmid": "20996328", "title": "The massacre of the Ardeatine Caves; identification of the dead.", "content": "The massacre of the Ardeatine Caves; identification of the dead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996328"}
{"pmid": "20996329", "title": "Military medicine in Italy; analysis of one year's work in a medical division.", "content": "Military medicine in Italy; analysis of one year's work in a medical division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996329"}
{"pmid": "20996330", "title": "A case of bilateral congenital hydro-ureter and hydronephrosis.", "content": "A case of bilateral congenital hydro-ureter and hydronephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996330"}
{"pmid": "20996331", "title": "Poliomyelitis in Singapore.", "content": "Poliomyelitis in Singapore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996331"}
{"pmid": "20996332", "title": "A case history of exfoliative dermatitis with complications.", "content": "A case history of exfoliative dermatitis with complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996332"}
{"pmid": "20996333", "title": "Development of the stretcher bed (Holman) and attachments.", "content": "Development of the stretcher bed (Holman) and attachments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996333"}
{"pmid": "20996335", "title": "Management of the shock ward.", "content": "Management of the shock ward.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996335"}
{"pmid": "20996336", "title": "Treatment of fracture-dislocations of the proximal interphalangeal joints of the fingers.", "content": "Treatment of fracture-dislocations of the proximal interphalangeal joints of the fingers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996336"}
{"pmid": "20996334", "title": "Acute myocardial infarction in men below forty.", "content": "Acute myocardial infarction in men below forty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996334"}
{"pmid": "20996337", "title": "Otomycosis; some remarks concerning its diagnosis and treatment.", "content": "Otomycosis; some remarks concerning its diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996337"}
{"pmid": "20996338", "title": "Bismuth gingivo stomatitis.", "content": "Bismuth gingivo stomatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996338"}
{"pmid": "20996339", "title": "Fractures of the clavicle in military trainees.", "content": "Fractures of the clavicle in military trainees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996339"}
{"pmid": "20996340", "title": "Immune serum globulin (gamma-globulin) in the prophylaxis of mumps orchitis.", "content": "Immune serum globulin (gamma-globulin) in the prophylaxis of mumps orchitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996340"}
{"pmid": "20996341", "title": "Sclerosing solution in treatment of pilonidal cysts.", "content": "Sclerosing solution in treatment of pilonidal cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996341"}
{"pmid": "20996342", "title": "Medical air evacuation in the Army Air Forces.", "content": "Medical air evacuation in the Army Air Forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996342"}
{"pmid": "20996343", "title": "Cervical murmurs with normal hearts.", "content": "Cervical murmurs with normal hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996343"}
{"pmid": "20996344", "title": "Voluntary nystagmus.", "content": "Voluntary nystagmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996344"}
{"pmid": "20996345", "title": "The responsibilities of an autopsy surgeon.", "content": "The responsibilities of an autopsy surgeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996345"}
{"pmid": "20996347", "title": "Veterans' education and training.", "content": "Veterans' education and training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996347"}
{"pmid": "20996346", "title": "Appraisal of rapid killing power of high velocity bullets.", "content": "Appraisal of rapid killing power of high velocity bullets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996346"}
{"pmid": "20996349", "title": "A high-temperature furnace for use under the microscope.", "content": "A high-temperature furnace for use under the microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996349"}
{"pmid": "20996348", "title": "Scientific method in the evolution of new drugs; the cell surface and drug action.", "content": "Scientific method in the evolution of new drugs; the cell surface and drug action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996348"}
{"pmid": "20996350", "title": "Action of iodine vapour on influenza virus in droplet suspension.", "content": "Action of iodine vapour on influenza virus in droplet suspension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996350"}
{"pmid": "20996351", "title": "A note on the interaction between heterosis and photoperiodic response.", "content": "A note on the interaction between heterosis and photoperiodic response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996351"}
{"pmid": "20996353", "title": "X-ray-induced depolymerization of thymonucleohistone and of sodium thymonucleate.", "content": "X-ray-induced depolymerization of thymonucleohistone and of sodium thymonucleate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996353"}
{"pmid": "20996352", "title": "The similarity of the effect of podophyllin and colchicine and their use in the treatment of condylomata acuminata.", "content": "The similarity of the effect of podophyllin and colchicine and their use in the treatment of condylomata acuminata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996352"}
{"pmid": "20996354", "title": "Effect of long ultraviolet radiation on the human eye.", "content": "Effect of long ultraviolet radiation on the human eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996354"}
{"pmid": "20996356", "title": "Saccharose-fermenting diphtheria bacilli.", "content": "Saccharose-fermenting diphtheria bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996356"}
{"pmid": "20996355", "title": "Maintenance of respiratory activity in stored peripheral nerve.", "content": "Maintenance of respiratory activity in stored peripheral nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996355"}
{"pmid": "20996357", "title": "A method for immunological and chemical investigations of body fluids by means of purified gelatin.", "content": "A method for immunological and chemical investigations of body fluids by means of purified gelatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996357"}
{"pmid": "20996359", "title": "Comparative digestibilities of plastic shortenings made from lard and from hydrogenated vegetable oils.", "content": "Comparative digestibilities of plastic shortenings made from lard and from hydrogenated vegetable oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996359"}
{"pmid": "20996360", "title": "On opinions of the International Commission on Zoological Nomenclature.", "content": "On opinions of the International Commission on Zoological Nomenclature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996360"}
{"pmid": "20996358", "title": "A method for obtaining standard suspension of tubercle bacilli in the form of single cells.", "content": "A method for obtaining standard suspension of tubercle bacilli in the form of single cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996358"}
{"pmid": "20996361", "title": "Presidential address.", "content": "Presidential address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996361"}
{"pmid": "20996362", "title": "Psychotherapeutic aspects of symptomatic treatment.", "content": "Psychotherapeutic aspects of symptomatic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996362"}
{"pmid": "20996363", "title": "The rôle of conditioned responses in emotional disturbances of war.", "content": "The rôle of conditioned responses in emotional disturbances of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996363"}
{"pmid": "20996364", "title": "A rapid personality evaluation; based on the Minnesota Multiphasic Personality Inventory and the Cornell Selectee Index.", "content": "A rapid personality evaluation; based on the Minnesota Multiphasic Personality Inventory and the Cornell Selectee Index.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996364"}
{"pmid": "20996365", "title": "Psychosomatic dermatological syndromes in military service.", "content": "Psychosomatic dermatological syndromes in military service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996365"}
{"pmid": "20996366", "title": "Why 2,276 American soldiers in the Mediterranean Theater of Operation were absent without leave, deserted, or misbehaved before the enemy.", "content": "Why 2,276 American soldiers in the Mediterranean Theater of Operation were absent without leave, deserted, or misbehaved before the enemy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996366"}
{"pmid": "20996367", "title": "Residuals of combat induced anxiety.", "content": "Residuals of combat induced anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996367"}
{"pmid": "20996368", "title": "On Oriental stoicism.", "content": "On Oriental stoicism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996368"}
{"pmid": "20996369", "title": "The psychologist's contribution to the psychiatric hospital.", "content": "The psychologist's contribution to the psychiatric hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996369"}
{"pmid": "20996370", "title": "Physical signs in schizophrenia.", "content": "Physical signs in schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996370"}
{"pmid": "20996371", "title": "Cerebral lesion resulting in spatial disorientation.", "content": "Cerebral lesion resulting in spatial disorientation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996371"}
{"pmid": "20996372", "title": "Conditioned response to fellatio.", "content": "Conditioned response to fellatio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996372"}
{"pmid": "20996374", "title": "Psychoneurotics in combat.", "content": "Psychoneurotics in combat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996374"}
{"pmid": "20996373", "title": "The selectee and his complaints.", "content": "The selectee and his complaints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996373"}
{"pmid": "20996375", "title": "A report on the use of the Wechsler-Bellevue scales in an overseas general hospital.", "content": "A report on the use of the Wechsler-Bellevue scales in an overseas general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996375"}
{"pmid": "20996376", "title": "Autofellatio.", "content": "Autofellatio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996376"}
{"pmid": "20996377", "title": "Personal problems related to Army rank.", "content": "Personal problems related to Army rank.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996377"}
{"pmid": "20996378", "title": "The psychopathic personality; the Rorschach patterns of 28 cases.", "content": "The psychopathic personality; the Rorschach patterns of 28 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996378"}
{"pmid": "20996379", "title": "VETERAN uses general semantics for rehabilitation.", "content": "VETERAN uses general semantics for rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996379"}
{"pmid": "20996380", "title": "Radical surgery and penicillin in brain abscess; a method of treatment in one stage with special reference to the cure of three thoracogenic cases.", "content": "Radical surgery and penicillin in brain abscess; a method of treatment in one stage with special reference to the cure of three thoracogenic cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996380"}
{"pmid": "20996381", "title": "Guides for nerve regeneration across gaps.", "content": "Guides for nerve regeneration across gaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996381"}
{"pmid": "20996382", "title": "Observations on encephalographic findings in cerebral trauma.", "content": "Observations on encephalographic findings in cerebral trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996382"}
{"pmid": "20996383", "title": "Separation at the suture site as a cause of failure in regeneration of peripheral nerves.", "content": "Separation at the suture site as a cause of failure in regeneration of peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996383"}
{"pmid": "20996384", "title": "Cortical localization by electroencephalography; the value of a quantitative and statistical analysis of homologous recordings obtained simultaneously.", "content": "Cortical localization by electroencephalography; the value of a quantitative and statistical analysis of homologous recordings obtained simultaneously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996384"}
{"pmid": "20996385", "title": "Anterior rhizotomy; the accurate identification of motor roots at the lower end of the spinal cord.", "content": "Anterior rhizotomy; the accurate identification of motor roots at the lower end of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996385"}
{"pmid": "20996386", "title": "Hydrocephalus; a contribution related to treatment.", "content": "Hydrocephalus; a contribution related to treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996386"}
{"pmid": "20996387", "title": "Mucocele of the sphenoid sinus; report of a case with autopsy findings.", "content": "Mucocele of the sphenoid sinus; report of a case with autopsy findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996387"}
{"pmid": "20996388", "title": "A technique for charting neurosurgical lesions.", "content": "A technique for charting neurosurgical lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996388"}
{"pmid": "20996390", "title": "Uterine cancer and precancerous diagnosis by cytology test.", "content": "Uterine cancer and precancerous diagnosis by cytology test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996390"}
{"pmid": "20996389", "title": "The posterior tibial reflex; a reflex of some value in the localization of the protruded intervertebral disc in the lumbar region.", "content": "The posterior tibial reflex; a reflex of some value in the localization of the protruded intervertebral disc in the lumbar region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996389"}
{"pmid": "20996391", "title": "When a nurse is the patient.", "content": "When a nurse is the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996391"}
{"pmid": "20996392", "title": "Rural immunization clinics.", "content": "Rural immunization clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996392"}
{"pmid": "20996393", "title": "Irradiation of nasopharyngeal lymphoid tissue; an evaluation.", "content": "Irradiation of nasopharyngeal lymphoid tissue; an evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996393"}
{"pmid": "20996394", "title": "Plastic repair of the deflected nasal septum.", "content": "Plastic repair of the deflected nasal septum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996394"}
{"pmid": "20996395", "title": "Modified radical mastoidectomy; the indications and the technic (semiradical mastoidectomy, modified tympanomastoidectomy, Heath mastoidectomy, Bondy mastoidectomy).", "content": "Modified radical mastoidectomy; the indications and the technic (semiradical mastoidectomy, modified tympanomastoidectomy, Heath mastoidectomy, Bondy mastoidectomy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996395"}
{"pmid": "20996396", "title": "Traumatic palatal fistula.", "content": "Traumatic palatal fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996396"}
{"pmid": "20996397", "title": "Absence or near absence of excitant effects from administration of tuamine.", "content": "Absence or near absence of excitant effects from administration of tuamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996397"}
{"pmid": "20996398", "title": "Penicillin in the field of otolaryngology; clinical and bacteriologic studies with special reference to topical applications.", "content": "Penicillin in the field of otolaryngology; clinical and bacteriologic studies with special reference to topical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996398"}
{"pmid": "20996399", "title": "Diplacusis and acuity of hearing.", "content": "Diplacusis and acuity of hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996399"}
{"pmid": "20996400", "title": "Laryngeal tuberculosis.", "content": "Laryngeal tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996400"}
{"pmid": "20996401", "title": "Nasopharynx in an epidemic of streptococcic infection.", "content": "Nasopharynx in an epidemic of streptococcic infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996401"}
{"pmid": "20996402", "title": "Cartilaginous septum in the reconstruction of the nose; a modified procedure.", "content": "Cartilaginous septum in the reconstruction of the nose; a modified procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996402"}
{"pmid": "20996403", "title": "Keloid formation in both ear lobes.", "content": "Keloid formation in both ear lobes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996403"}
{"pmid": "20996404", "title": "Leiomyoma of the larynx.", "content": "Leiomyoma of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996404"}
{"pmid": "20996405", "title": "Laryngocele.", "content": "Laryngocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996405"}
{"pmid": "20996406", "title": "Otitis media and complications.", "content": "Otitis media and complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996406"}
{"pmid": "20996407", "title": "Sulfonamide toxicity; interpretation of laboratory findings.", "content": "Sulfonamide toxicity; interpretation of laboratory findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996407"}
{"pmid": "20996409", "title": "Glaucoma with cataract.", "content": "Glaucoma with cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996409"}
{"pmid": "20996408", "title": "The external ear and drum membrane in otosclerosis.", "content": "The external ear and drum membrane in otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996408"}
{"pmid": "20996410", "title": "Irradiation of nasopharyngeal lymphoid tissue in prevention of conduction deafness.", "content": "Irradiation of nasopharyngeal lymphoid tissue in prevention of conduction deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996410"}
{"pmid": "20996411", "title": "Poliomyelitis and tonsillectomy; is there a relationship?", "content": "Poliomyelitis and tonsillectomy; is there a relationship?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996411"}
{"pmid": "20996412", "title": "Functional pathology of vertigo.", "content": "Functional pathology of vertigo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996412"}
{"pmid": "20996413", "title": "Gunshot wound of the right maxillary sinus.", "content": "Gunshot wound of the right maxillary sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996413"}
{"pmid": "20996415", "title": "The syndrome of leukanaemia.", "content": "The syndrome of leukanaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996415"}
{"pmid": "20996414", "title": "Growth hormones and atrophic rhinitis.", "content": "Growth hormones and atrophic rhinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996414"}
{"pmid": "20996416", "title": "The relative susceptibility to phagocytosis of gravis and mitis types of C. diphtheriae.", "content": "The relative susceptibility to phagocytosis of gravis and mitis types of C. diphtheriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996416"}
{"pmid": "20996417", "title": "Relapsing febrile nodular inflammation of adipose tissue (Weber-Christian syndrome); report of a case with autopsy.", "content": "Relapsing febrile nodular inflammation of adipose tissue (Weber-Christian syndrome); report of a case with autopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996417"}
{"pmid": "20996418", "title": "A substance in human serum inhibiting staphylocoagulase.", "content": "A substance in human serum inhibiting staphylocoagulase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996418"}
{"pmid": "20996420", "title": "Thrombosis as a factor in the pathogenesis of coronary atherosclerosis.", "content": "Thrombosis as a factor in the pathogenesis of coronary atherosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996420"}
{"pmid": "20996419", "title": "The lesions of sheep dermatitis virus infection in the rabbit and guinea-pig with particular reference to the tumour viruses.", "content": "The lesions of sheep dermatitis virus infection in the rabbit and guinea-pig with particular reference to the tumour viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996419"}
{"pmid": "20996421", "title": "An experimental study of some effects of acute anhydraemia.", "content": "An experimental study of some effects of acute anhydraemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996421"}
{"pmid": "20996422", "title": "The ABO blood groups in the United Kingdom; frequencies based on a very large sample.", "content": "The ABO blood groups in the United Kingdom; frequencies based on a very large sample.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996422"}
{"pmid": "20996423", "title": "The collagenase (kappa toxin) of Cl. welchii type A.", "content": "The collagenase (kappa toxin) of Cl. welchii type A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996423"}
{"pmid": "20996424", "title": "Laboratory findings in clinical dysentery in Middle East Force between August 1940 and June 1943.", "content": "Laboratory findings in clinical dysentery in Middle East Force between August 1940 and June 1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996424"}
{"pmid": "20996425", "title": "Two cases of multiple myeloma (plasmocytoma) with secondary deposits in the dura mater.", "content": "Two cases of multiple myeloma (plasmocytoma) with secondary deposits in the dura mater.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996425"}
{"pmid": "20996426", "title": "The effect of temperature on non-specific infections of fish.", "content": "The effect of temperature on non-specific infections of fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996426"}
{"pmid": "20996427", "title": "Skin and nose carriage of bacteriophage types of Staph. aureus.", "content": "Skin and nose carriage of bacteriophage types of Staph. aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996427"}
{"pmid": "20996428", "title": "The frequencies of bacterial sub-types in a carrier community and their significance.", "content": "The frequencies of bacterial sub-types in a carrier community and their significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996428"}
{"pmid": "20996429", "title": "Azotoluene bladder tumours in rats.", "content": "Azotoluene bladder tumours in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996429"}
{"pmid": "20996430", "title": "The influence of certain antagonistic organisms upon acid-fast bacteria.", "content": "The influence of certain antagonistic organisms upon acid-fast bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996430"}
{"pmid": "20996431", "title": "The incidence of sera containing agglutinins for Br. abortus among samples submitted for the Wassermann reaction and the Widal test.", "content": "The incidence of sera containing agglutinins for Br. abortus among samples submitted for the Wassermann reaction and the Widal test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996431"}
{"pmid": "20996432", "title": "An intrapericardial teratoma in an infant.", "content": "An intrapericardial teratoma in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996432"}
{"pmid": "20996433", "title": "Sarcoma of the diagphragm with an intra-aortic metastasis.", "content": "Sarcoma of the diagphragm with an intra-aortic metastasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996433"}
{"pmid": "20996434", "title": "Dissecting aneurysm of the aorta associated with intracranial aneurysm and cerebral haemorrhage.", "content": "Dissecting aneurysm of the aorta associated with intracranial aneurysm and cerebral haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996434"}
{"pmid": "20996435", "title": "A case of solitary mucus-secreting cystadenoma of the urinary bladder.", "content": "A case of solitary mucus-secreting cystadenoma of the urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996435"}
{"pmid": "20996436", "title": "Tuberculosis in an adenolymphoma of the parotid gland.", "content": "Tuberculosis in an adenolymphoma of the parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996436"}
{"pmid": "20996437", "title": "An intramural cardiac aneurysm.", "content": "An intramural cardiac aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996437"}
{"pmid": "20996438", "title": "Two new types of Shigella flexneri.", "content": "Two new types of Shigella flexneri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996438"}
{"pmid": "20996439", "title": "The metabolism of glutamine by micro-organisms in relation to the need by haemolytic streptococci for added glutamine in growth.", "content": "The metabolism of glutamine by micro-organisms in relation to the need by haemolytic streptococci for added glutamine in growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996439"}
{"pmid": "20996440", "title": "Chorionepithelioma testis.", "content": "Chorionepithelioma testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996440"}
{"pmid": "20996442", "title": "Clinical ascariasis.", "content": "Clinical ascariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996442"}
{"pmid": "20996441", "title": "Estivoautumnal (Plasmodium falciparum) malaria; a survey of four hundred and ninety-three cases of infection with Plasmodium falciparum in children.", "content": "Estivoautumnal (Plasmodium falciparum) malaria; a survey of four hundred and ninety-three cases of infection with Plasmodium falciparum in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996441"}
{"pmid": "20996443", "title": "Human infections with Salmonella panama.", "content": "Human infections with Salmonella panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996443"}
{"pmid": "20996444", "title": "Causes of prematurity; influence of infections, chronic disorders and accidents on the incidence of prematurity.", "content": "Causes of prematurity; influence of infections, chronic disorders and accidents on the incidence of prematurity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996444"}
{"pmid": "20996445", "title": "Acute lymphatic leukemia and pregnancy.", "content": "Acute lymphatic leukemia and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996445"}
{"pmid": "20996446", "title": "Spontaneous pneumothorax in the newborn.", "content": "Spontaneous pneumothorax in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996446"}
{"pmid": "20996448", "title": "Tonsils hypertrophy; pediatric aspects.", "content": "Tonsils hypertrophy; pediatric aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996448"}
{"pmid": "20996447", "title": "Primary tuberculosis of the conjunctiva.", "content": "Primary tuberculosis of the conjunctiva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996447"}
{"pmid": "20996449", "title": "Tonsils hypertrophy; rhinopharyngeal aspects.", "content": "Tonsils hypertrophy; rhinopharyngeal aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996449"}
{"pmid": "20996450", "title": "Tonsils hypertrophy; roentgen aspects.", "content": "Tonsils hypertrophy; roentgen aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996450"}
{"pmid": "20996451", "title": "Patent ductus arteriosus with superimposed Staphylococcus aureus endarteritis.", "content": "Patent ductus arteriosus with superimposed Staphylococcus aureus endarteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996451"}
{"pmid": "20996453", "title": "Micrognathia.", "content": "Micrognathia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996453"}
{"pmid": "20996452", "title": "Coarctation of the aorta, with superimposed bacterial endarteritis.", "content": "Coarctation of the aorta, with superimposed bacterial endarteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996452"}
{"pmid": "20996454", "title": "Thyrotoxicosis in a child managed with thiouracil.", "content": "Thyrotoxicosis in a child managed with thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996454"}
{"pmid": "20996455", "title": "Allergy in pediatrics.", "content": "Allergy in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996455"}
{"pmid": "20996456", "title": "Foreign body vaginitis.", "content": "Foreign body vaginitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996456"}
{"pmid": "20996458", "title": "Arachnodactyly.", "content": "Arachnodactyly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996458"}
{"pmid": "20996457", "title": "Thrombocytopenic purpura.", "content": "Thrombocytopenic purpura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996457"}
{"pmid": "20996459", "title": "Generalized vaccinia.", "content": "Generalized vaccinia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996459"}
{"pmid": "20996460", "title": "Peanut in the lung.", "content": "Peanut in the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996460"}
{"pmid": "20996461", "title": "Penicillin sensitivity.", "content": "Penicillin sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996461"}
{"pmid": "20996463", "title": "SURVEY of pharmaceutical education in the United States.", "content": "SURVEY of pharmaceutical education in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996463"}
{"pmid": "20996462", "title": "Hypoplasia of the adrenal glands.", "content": "Hypoplasia of the adrenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996462"}
{"pmid": "20996464", "title": "Historical research in pharmacy.", "content": "Historical research in pharmacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996464"}
{"pmid": "20996465", "title": "The interrelationship of pharmacy and medicine.", "content": "The interrelationship of pharmacy and medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996465"}
{"pmid": "20996466", "title": "What value animal experimentation.", "content": "What value animal experimentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996466"}
{"pmid": "20996468", "title": "Limitation of enrollment in colleges of pharmacy.", "content": "Limitation of enrollment in colleges of pharmacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996468"}
{"pmid": "20996467", "title": "Identification tests on pharmaceutical preparations.", "content": "Identification tests on pharmaceutical preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996467"}
{"pmid": "20996469", "title": "Is acceleration a suitable program for peacetime pharmaceutical education?", "content": "Is acceleration a suitable program for peacetime pharmaceutical education?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996469"}
{"pmid": "20996470", "title": "Surgical ligatures and sutures.", "content": "Surgical ligatures and sutures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996470"}
{"pmid": "20996471", "title": "Disintegration tests for tablets.", "content": "Disintegration tests for tablets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996471"}
{"pmid": "20996472", "title": "A study of the equilibria in solutions of neutral derivatives of sulphonamides.", "content": "A study of the equilibria in solutions of neutral derivatives of sulphonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996472"}
{"pmid": "20996474", "title": "The present status of haemorrhoidal preparations.", "content": "The present status of haemorrhoidal preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996474"}
{"pmid": "20996473", "title": "The stability of adrenaline solutions; storage of the proposed solution of adrenaline hydrochloride and injection of adrenaline tartrate.", "content": "The stability of adrenaline solutions; storage of the proposed solution of adrenaline hydrochloride and injection of adrenaline tartrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996473"}
{"pmid": "20996475", "title": "Symposium on penicillin.", "content": "Symposium on penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996475"}
{"pmid": "20996476", "title": "Some aspects of penicillin stability.", "content": "Some aspects of penicillin stability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996476"}
{"pmid": "20996477", "title": "Sex hormones.", "content": "Sex hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996477"}
{"pmid": "20996478", "title": "MUSHROOM poisoning; the danger of Amanita phalloides.", "content": "MUSHROOM poisoning; the danger of Amanita phalloides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996478"}
{"pmid": "20996479", "title": "CONTROL of proprietary medicines, an indictment.", "content": "CONTROL of proprietary medicines, an indictment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996479"}
{"pmid": "20996480", "title": "A note on pharmacy in Hungary.", "content": "A note on pharmacy in Hungary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996480"}
{"pmid": "20996481", "title": "The chemotherapy of malaria.", "content": "The chemotherapy of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996481"}
{"pmid": "20996482", "title": "Parenteral solutions of penicillin.", "content": "Parenteral solutions of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996482"}
{"pmid": "20996483", "title": "Developments in galenical production.", "content": "Developments in galenical production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996483"}
{"pmid": "20996484", "title": "The choice of drugs in diseases of the chest.", "content": "The choice of drugs in diseases of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996484"}
{"pmid": "20996486", "title": "A forgotten Russian pharmacist; the discoverer of ruthenium.", "content": "A forgotten Russian pharmacist; the discoverer of ruthenium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996486"}
{"pmid": "20996485", "title": "Improvised biochemical work of a prisoner of war.", "content": "Improvised biochemical work of a prisoner of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996485"}
{"pmid": "20996487", "title": "Radioactive indicators in biological tracer work.", "content": "Radioactive indicators in biological tracer work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996487"}
{"pmid": "20996488", "title": "A theoretical study of the composition of the alveolar air at altitude.", "content": "A theoretical study of the composition of the alveolar air at altitude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996488"}
{"pmid": "20996489", "title": "The effect of hemorrhage on the plasma amino nitrogen of the dog.", "content": "The effect of hemorrhage on the plasma amino nitrogen of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996489"}
{"pmid": "20996490", "title": "The effect of the infusion of renin on the flow and protein content of the lymph of anesthetized dogs.", "content": "The effect of the infusion of renin on the flow and protein content of the lymph of anesthetized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996490"}
{"pmid": "20996491", "title": "The influence of hepatectomy on the relative concentration of the protein components of dog plasma as determined by electrophoresis.", "content": "The influence of hepatectomy on the relative concentration of the protein components of dog plasma as determined by electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996491"}
{"pmid": "20996492", "title": "The effect of intra-arterially injected adrenalin on blood flow, sugar retention and lactate output of the leg tissues of anesthetized cats.", "content": "The effect of intra-arterially injected adrenalin on blood flow, sugar retention and lactate output of the leg tissues of anesthetized cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996492"}
{"pmid": "20996493", "title": "The dark adaptation of the color anomalous.", "content": "The dark adaptation of the color anomalous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996493"}
{"pmid": "20996494", "title": "The effect of para-aminopropiophenone-induced methemoglobinemia on oxygenation of working muscle in human subjects.", "content": "The effect of para-aminopropiophenone-induced methemoglobinemia on oxygenation of working muscle in human subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996494"}
{"pmid": "20996495", "title": "The respiratory metabolism of human subjects during prolonged exposures to simulated altitudes of 8000 and 10,000 feet.", "content": "The respiratory metabolism of human subjects during prolonged exposures to simulated altitudes of 8000 and 10,000 feet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996495"}
{"pmid": "20996496", "title": "Pyridoxine deficiency in dogs as affected by level of dietary protein.", "content": "Pyridoxine deficiency in dogs as affected by level of dietary protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996496"}
{"pmid": "20996497", "title": "Simultaneous determinations of blood volume by CO and dye (T-1824) under various conditions.", "content": "Simultaneous determinations of blood volume by CO and dye (T-1824) under various conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996497"}
{"pmid": "20996498", "title": "A systematic error in Kuhlmann-Anderson mental ages.", "content": "A systematic error in Kuhlmann-Anderson mental ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996498"}
{"pmid": "20996499", "title": "Adjustment of adolescent daughters of employed women to family life.", "content": "Adjustment of adolescent daughters of employed women to family life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996499"}
{"pmid": "20996500", "title": "Age and sex differences in the perception of incomplete pictures by adults.", "content": "Age and sex differences in the perception of incomplete pictures by adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996500"}
{"pmid": "20996501", "title": "Behavior notes on E. insularis Hentz; domestication, involution.", "content": "Behavior notes on E. insularis Hentz; domestication, involution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996501"}
{"pmid": "20996502", "title": "A preschool form of the symbols scale.", "content": "A preschool form of the symbols scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996502"}
{"pmid": "20996503", "title": "Emancipation status of college students.", "content": "Emancipation status of college students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996503"}
{"pmid": "20996504", "title": "Auditory changes in children from ages ten to eighteen.", "content": "Auditory changes in children from ages ten to eighteen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996504"}
{"pmid": "20996505", "title": "The invariability of certain coefficients of correlation during human development.", "content": "The invariability of certain coefficients of correlation during human development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996505"}
{"pmid": "20996506", "title": "A study of feeding mechanisms in premature infants.", "content": "A study of feeding mechanisms in premature infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996506"}
{"pmid": "20996507", "title": "A comparative study of some problems of social and emotional adjustment of crippled and non-crippled girls and boys.", "content": "A comparative study of some problems of social and emotional adjustment of crippled and non-crippled girls and boys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996507"}
{"pmid": "20996511", "title": "Hygeialogy; the art and science of personal health.", "content": "Hygeialogy; the art and science of personal health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996511"}
{"pmid": "20996512", "title": "The preparation of the public health nurse for service in rural health units.", "content": "The preparation of the public health nurse for service in rural health units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996512"}
{"pmid": "20996513", "title": "Meeting the challenge of school lunch programs for rural areas.", "content": "Meeting the challenge of school lunch programs for rural areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996513"}
{"pmid": "20996514", "title": "An outbreak of typhoid fever in Trenton, Nova Scotia.", "content": "An outbreak of typhoid fever in Trenton, Nova Scotia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996514"}
{"pmid": "20996515", "title": "Pertussis immunization in Edmonton.", "content": "Pertussis immunization in Edmonton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996515"}
{"pmid": "20996516", "title": "Public health nursing in the control of syphilis and gonorrhoea.", "content": "Public health nursing in the control of syphilis and gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996516"}
{"pmid": "20996517", "title": "The College Physical Education Association.", "content": "The College Physical Education Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996517"}
{"pmid": "20996518", "title": "The relationship between the health and physical education department and the medical center.", "content": "The relationship between the health and physical education department and the medical center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996518"}
{"pmid": "20996519", "title": "What is early tuberculosis?", "content": "What is early tuberculosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996519"}
{"pmid": "20996521", "title": "CONTROL of bovine tuberculosis in the United States.", "content": "CONTROL of bovine tuberculosis in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996521"}
{"pmid": "20996520", "title": "BCG vaccination in Denmark.", "content": "BCG vaccination in Denmark.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996520"}
{"pmid": "20996522", "title": "CHARACTERISTICS of commercial x-ray intensifying screens.", "content": "CHARACTERISTICS of commercial x-ray intensifying screens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996522"}
{"pmid": "20996523", "title": "The black fly, Simulium (Eusimulium) smarti, n. sp. (Diptera: Simuliidae) of the onchocercosis zone of the State of Chiapas, México.", "content": "The black fly, Simulium (Eusimulium) smarti, n. sp. (Diptera: Simuliidae) of the onchocercosis zone of the State of Chiapas, México.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996523"}
{"pmid": "20996525", "title": "The complement-fixation and Weil-Felix reactions in a study of typhus among wild rats.", "content": "The complement-fixation and Weil-Felix reactions in a study of typhus among wild rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996525"}
{"pmid": "20996524", "title": "Treatment of schistosomiasis mansoni with antimony lithium thiomalate (anthiomaline).", "content": "Treatment of schistosomiasis mansoni with antimony lithium thiomalate (anthiomaline).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996524"}
{"pmid": "20996526", "title": "Intestinal cestode infections in natives of Panama.", "content": "Intestinal cestode infections in natives of Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996526"}
{"pmid": "20996527", "title": "Incidence of intestinal protozoa among patients of the University Hospital at San Juan, Puerto Rico.", "content": "Incidence of intestinal protozoa among patients of the University Hospital at San Juan, Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996527"}
{"pmid": "20996528", "title": "The increase of bacteriophage in vivo during experimental infections with Shigella paradysenteriae Flexner in mice.", "content": "The increase of bacteriophage in vivo during experimental infections with Shigella paradysenteriae Flexner in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996528"}
{"pmid": "20996529", "title": "Isospora hominis Fantham, 1917, in Puerto Rico.", "content": "Isospora hominis Fantham, 1917, in Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996529"}
{"pmid": "20996530", "title": "Filtration of water through diatomaceous earth.", "content": "Filtration of water through diatomaceous earth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996530"}
{"pmid": "20996531", "title": "Radiographers and radiography.", "content": "Radiographers and radiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996531"}
{"pmid": "20996532", "title": "Wooden chest stand, for use with trolley patients.", "content": "Wooden chest stand, for use with trolley patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996532"}
{"pmid": "20996533", "title": "The essential features of a modern x-ray department.", "content": "The essential features of a modern x-ray department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996533"}
{"pmid": "20996534", "title": "The shock of battle wounds; a review of the treatment in 2,000 casualties.", "content": "The shock of battle wounds; a review of the treatment in 2,000 casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996534"}
{"pmid": "20996535", "title": "A review of the Blood Donor Service of the American Red Cross.", "content": "A review of the Blood Donor Service of the American Red Cross.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996535"}
{"pmid": "20996536", "title": "The use of blood and plasma in the treatment of battle casualties.", "content": "The use of blood and plasma in the treatment of battle casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996536"}
{"pmid": "20996537", "title": "Penicillin and its use in the war wounded.", "content": "Penicillin and its use in the war wounded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996537"}
{"pmid": "20996538", "title": "The function of thoracic surgery centers in World War II.", "content": "The function of thoracic surgery centers in World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996538"}
{"pmid": "20996540", "title": "Perforating wounds of the colon and rectum.", "content": "Perforating wounds of the colon and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996540"}
{"pmid": "20996539", "title": "Surgical management of war wounds of the abdomen.", "content": "Surgical management of war wounds of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996539"}
{"pmid": "20996541", "title": "Rehabilitation of the injured hand.", "content": "Rehabilitation of the injured hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996541"}
{"pmid": "20996543", "title": "Repair of avulsion wounds of the hands and feet by the flap graft technic.", "content": "Repair of avulsion wounds of the hands and feet by the flap graft technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996543"}
{"pmid": "20996542", "title": "Bone surgery of the hand.", "content": "Bone surgery of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996542"}
{"pmid": "20996544", "title": "Splints and casts in the treatment of war injuries.", "content": "Splints and casts in the treatment of war injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996544"}
{"pmid": "20996545", "title": "Fractures of the upper extremity; a review of experiences in World War II.", "content": "Fractures of the upper extremity; a review of experiences in World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996545"}
{"pmid": "20996546", "title": "Rehabilitation of the surgical patient in Army hospitals in World War II.", "content": "Rehabilitation of the surgical patient in Army hospitals in World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996546"}
{"pmid": "20996547", "title": "Fractures and dislocations of the spine in warfare.", "content": "Fractures and dislocations of the spine in warfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996547"}
{"pmid": "20996548", "title": "Acute war wounds of the spinal cord.", "content": "Acute war wounds of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996548"}
{"pmid": "20996549", "title": "Management of war wounds of the cranial cavity.", "content": "Management of war wounds of the cranial cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996549"}
{"pmid": "20996550", "title": "Penetrating wounds of the brain; management in an evacuation hospital.", "content": "Penetrating wounds of the brain; management in an evacuation hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996550"}
{"pmid": "20996551", "title": "Surgical problems in the late management of craniocerebral injuries with special reference to the repair of cranial defects with tantalum plate.", "content": "Surgical problems in the late management of craniocerebral injuries with special reference to the repair of cranial defects with tantalum plate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996551"}
{"pmid": "20996552", "title": "Painful injuries of nerves and their surgical treatment.", "content": "Painful injuries of nerves and their surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996552"}
{"pmid": "20996553", "title": "The repair of peripheral nerve lesions.", "content": "The repair of peripheral nerve lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996553"}
{"pmid": "20996554", "title": "Surgery in Japanese prison camps.", "content": "Surgery in Japanese prison camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996554"}
{"pmid": "20996555", "title": "Some aspects of the diagnosis and treatment of prolapsed intervertebral discs.", "content": "Some aspects of the diagnosis and treatment of prolapsed intervertebral discs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996555"}
{"pmid": "20996556", "title": "Surgery of the patent ductus arteriosus.", "content": "Surgery of the patent ductus arteriosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996556"}
{"pmid": "20996557", "title": "Notes on the treatment of penetrating head wounds in a base neurosurgical unit.", "content": "Notes on the treatment of penetrating head wounds in a base neurosurgical unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996557"}
{"pmid": "20996558", "title": "Carcinoma of the prostate; its treatment by modern methods.", "content": "Carcinoma of the prostate; its treatment by modern methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996558"}
{"pmid": "20996559", "title": "Acute regional entero-colitis with a report of three cases.", "content": "Acute regional entero-colitis with a report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996559"}
{"pmid": "20996560", "title": "The early treatment of battle casualties of soft tissues and bone.", "content": "The early treatment of battle casualties of soft tissues and bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996560"}
{"pmid": "20996561", "title": "Penicillin treatment of experimental osteomyelitis in rabbits.", "content": "Penicillin treatment of experimental osteomyelitis in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996561"}
{"pmid": "20996562", "title": "Resection of pulmonary tissue in tuberculosis.", "content": "Resection of pulmonary tissue in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996562"}
{"pmid": "20996563", "title": "Psoas abscess following acute appendicitis.", "content": "Psoas abscess following acute appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996563"}
{"pmid": "20996564", "title": "Advanced cardiospasm; report of a case treated by cardioplasty.", "content": "Advanced cardiospasm; report of a case treated by cardioplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996564"}
{"pmid": "20996565", "title": "Painful phantom limb treated by high cervical chordotomy.", "content": "Painful phantom limb treated by high cervical chordotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996565"}
{"pmid": "20996566", "title": "Vascular tumours of the spinal cord associated with skin haemangiomata.", "content": "Vascular tumours of the spinal cord associated with skin haemangiomata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996566"}
{"pmid": "20996567", "title": "The management and surgical resurfacing of serious burns.", "content": "The management and surgical resurfacing of serious burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996567"}
{"pmid": "20996568", "title": "Injuries to the pancreas and their surgical treatment.", "content": "Injuries to the pancreas and their surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996568"}
{"pmid": "20996569", "title": "Paroxysmal hyperinsulinism due to islet-cell tumour of the pancreas.", "content": "Paroxysmal hyperinsulinism due to islet-cell tumour of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996569"}
{"pmid": "20996570", "title": "The present position of surgery in the treatment of bleeding peptic ulcer.", "content": "The present position of surgery in the treatment of bleeding peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996570"}
{"pmid": "20996571", "title": "A micro-incineration study of the flat epithelial layer covering the alimentary tract.", "content": "A micro-incineration study of the flat epithelial layer covering the alimentary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996571"}
{"pmid": "20996572", "title": "Metastatic osteomyelitis secondary to tropical ulcer.", "content": "Metastatic osteomyelitis secondary to tropical ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996572"}
{"pmid": "20996573", "title": "Tendon transplantation for radial paralysis.", "content": "Tendon transplantation for radial paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996573"}
{"pmid": "20996574", "title": "A case of severe electric burns with an unusual sequence of complications.", "content": "A case of severe electric burns with an unusual sequence of complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996574"}
{"pmid": "20996575", "title": "Three cases of fracture-dislocation of the hip occurring simultaneously in one car accident.", "content": "Three cases of fracture-dislocation of the hip occurring simultaneously in one car accident.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996575"}
{"pmid": "20996576", "title": "Simultaneous carcinoma and tuberculosis of the colon; report of a case and review of the literature.", "content": "Simultaneous carcinoma and tuberculosis of the colon; report of a case and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996576"}
{"pmid": "20996577", "title": "Solid tumours of the epididymis.", "content": "Solid tumours of the epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996577"}
{"pmid": "20996578", "title": "Congenital atresia of the common bile-duct.", "content": "Congenital atresia of the common bile-duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996578"}
{"pmid": "20996580", "title": "Suture of the external and internal popliteal nerves.", "content": "Suture of the external and internal popliteal nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996580"}
{"pmid": "20996579", "title": "Osteochondritis dissecans and torn lateral meniscus.", "content": "Osteochondritis dissecans and torn lateral meniscus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996579"}
{"pmid": "20996581", "title": "Haematemesis from erosion of the splenic artery by peptic ulceration.", "content": "Haematemesis from erosion of the splenic artery by peptic ulceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996581"}
{"pmid": "20996582", "title": "The surgical treatment of severe epistaxis in relation to the ethmoidal arteries.", "content": "The surgical treatment of severe epistaxis in relation to the ethmoidal arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996582"}
{"pmid": "20996583", "title": "Retrograde intussusception of lesser curvature of stomach, pylorus, and first part of the duodenum into the oesophagus.", "content": "Retrograde intussusception of lesser curvature of stomach, pylorus, and first part of the duodenum into the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996583"}
{"pmid": "20996584", "title": "A case of bilateral pneumothorax and bilateral penetrating wounds of the diaphragm with recovery.", "content": "A case of bilateral pneumothorax and bilateral penetrating wounds of the diaphragm with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996584"}
{"pmid": "20996585", "title": "A case of filarial funiculitis.", "content": "A case of filarial funiculitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996585"}
{"pmid": "20996586", "title": "Bayonet wound of the transverse colon.", "content": "Bayonet wound of the transverse colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996586"}
{"pmid": "20996587", "title": "A case of carcinoma coli in a child.", "content": "A case of carcinoma coli in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996587"}
{"pmid": "20996588", "title": "Traumatic aneurysm of the common carotid artery associated with massive infarction of the brain.", "content": "Traumatic aneurysm of the common carotid artery associated with massive infarction of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996588"}
{"pmid": "20996589", "title": "The role of thoracic disease in the production of arm pain.", "content": "The role of thoracic disease in the production of arm pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996589"}
{"pmid": "20996590", "title": "Arm pain due to heart disease.", "content": "Arm pain due to heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996590"}
{"pmid": "20996591", "title": "Pain in the upper extremity caused by peripheral vascular disease.", "content": "Pain in the upper extremity caused by peripheral vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996591"}
{"pmid": "20996592", "title": "Neurologic causes of pain in the upper extremities; with particular reference to syndromes of protruded intervertebral disk in the cervical region and mechanical compression of the brachial plexus.", "content": "Neurologic causes of pain in the upper extremities; with particular reference to syndromes of protruded intervertebral disk in the cervical region and mechanical compression of the brachial plexus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996592"}
{"pmid": "20996593", "title": "Lesions of the brachial plexus; syndromes of mechanical compression of the brachial plexus.", "content": "Lesions of the brachial plexus; syndromes of mechanical compression of the brachial plexus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996593"}
{"pmid": "20996594", "title": "Orthopedic aspects of pain in the shoulder and arm.", "content": "Orthopedic aspects of pain in the shoulder and arm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996594"}
{"pmid": "20996595", "title": "Cranioplasty with tantalum plate in the postwar period.", "content": "Cranioplasty with tantalum plate in the postwar period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996595"}
{"pmid": "20996596", "title": "Problems of facial prosthesis.", "content": "Problems of facial prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996596"}
{"pmid": "20996597", "title": "Malignant tumors of the scalp.", "content": "Malignant tumors of the scalp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996597"}
{"pmid": "20996599", "title": "Selection of patients for the fenestration operation for otosclerosis.", "content": "Selection of patients for the fenestration operation for otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996599"}
{"pmid": "20996598", "title": "Malignant lymphocytic tumors of the orbit.", "content": "Malignant lymphocytic tumors of the orbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996598"}
{"pmid": "20996601", "title": "Some technical aspects of surgery of the thyroid gland.", "content": "Some technical aspects of surgery of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996601"}
{"pmid": "20996600", "title": "Skin grafting methods and their indications.", "content": "Skin grafting methods and their indications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996600"}
{"pmid": "20996602", "title": "Complications and treatment of bronchial adenomas.", "content": "Complications and treatment of bronchial adenomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996602"}
{"pmid": "20996603", "title": "Total gastrectomy; report of a patient surviving for 8 years.", "content": "Total gastrectomy; report of a patient surviving for 8 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996603"}
{"pmid": "20996604", "title": "Resection of the head of the pancreas and duodenum; operative technic.", "content": "Resection of the head of the pancreas and duodenum; operative technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996604"}
{"pmid": "20996605", "title": "Total and subtotal colectomy with review of 72 cases.", "content": "Total and subtotal colectomy with review of 72 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996605"}
{"pmid": "20996606", "title": "Remarks concerning malignant lesions, polypoid disease and diverticula of the terminal portion of the large intestine.", "content": "Remarks concerning malignant lesions, polypoid disease and diverticula of the terminal portion of the large intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996606"}
{"pmid": "20996607", "title": "Proctologic diagnosis.", "content": "Proctologic diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996607"}
{"pmid": "20996608", "title": "Protruded intervertebral disk.", "content": "Protruded intervertebral disk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996608"}
{"pmid": "20996610", "title": "Indications for complete abdominal hysterectomy.", "content": "Indications for complete abdominal hysterectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996610"}
{"pmid": "20996609", "title": "Further observations on the treatment of carcinoma of the prostate by bilateral orchectomy.", "content": "Further observations on the treatment of carcinoma of the prostate by bilateral orchectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996609"}
{"pmid": "20996611", "title": "Obstruction following gastrojejunostomy; its biochemical factors.", "content": "Obstruction following gastrojejunostomy; its biochemical factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996611"}
{"pmid": "20996612", "title": "Delayed healing of an abdominal wound due to food allergy.", "content": "Delayed healing of an abdominal wound due to food allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996612"}
{"pmid": "20996613", "title": "Thyrotoxicosis and pregnancy.", "content": "Thyrotoxicosis and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996613"}
{"pmid": "20996614", "title": "Pyogenic infection of the spinal epidural space.", "content": "Pyogenic infection of the spinal epidural space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996614"}
{"pmid": "20996615", "title": "Prophylactic treatment of congenital syphilis.", "content": "Prophylactic treatment of congenital syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996615"}
{"pmid": "20996616", "title": "Symposium on the use and abuse of bed-rest.", "content": "Symposium on the use and abuse of bed-rest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996616"}
{"pmid": "20996617", "title": "Symposium on the use and abuse of bed-rest; urology.", "content": "Symposium on the use and abuse of bed-rest; urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996617"}
{"pmid": "20996618", "title": "Symposium on the use and abuse of bed-rest; orthopedics.", "content": "Symposium on the use and abuse of bed-rest; orthopedics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996618"}
{"pmid": "20996619", "title": "Symposium on the use and abuse of bed-rest; medicine.", "content": "Symposium on the use and abuse of bed-rest; medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996619"}
{"pmid": "20996620", "title": "Therapy of lowback pain by manipulation and of referred pain in the lower extremity by procaine infiltration.", "content": "Therapy of lowback pain by manipulation and of referred pain in the lower extremity by procaine infiltration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996620"}
{"pmid": "20996622", "title": "A special knee brace.", "content": "A special knee brace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996622"}
{"pmid": "20996621", "title": "Physicopyrexia and the biologic healing of early and late syphilis of the rabbit.", "content": "Physicopyrexia and the biologic healing of early and late syphilis of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996621"}
{"pmid": "20996623", "title": "COMMUNITY hospitals as civilian rehabilitation centers.", "content": "COMMUNITY hospitals as civilian rehabilitation centers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996623"}
{"pmid": "20996624", "title": "An improvised whirlpool.", "content": "An improvised whirlpool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996624"}
{"pmid": "20996625", "title": "Experimental studies of Bullis fever and dengue fever.", "content": "Experimental studies of Bullis fever and dengue fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996625"}
{"pmid": "20996626", "title": "The residual spraying of dwellings with DDT in the control of malaria transmission in Panama, with special reference to Anopheles albimanus.", "content": "The residual spraying of dwellings with DDT in the control of malaria transmission in Panama, with special reference to Anopheles albimanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996626"}
{"pmid": "20996627", "title": "Epidemic encephalitis in the Far East, a review.", "content": "Epidemic encephalitis in the Far East, a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996627"}
{"pmid": "20996629", "title": "Studies on cyclic passage of yellow fever virus in South American mammals and mosquitoes; marmosets (Callithrix penicillata and Leontocebus chrysomelas) in combination with Aedes aegypti.", "content": "Studies on cyclic passage of yellow fever virus in South American mammals and mosquitoes; marmosets (Callithrix penicillata and Leontocebus chrysomelas) in combination with Aedes aegypti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996629"}
{"pmid": "20996628", "title": "Experiments with various Colombian marsupials and primates in laboratory cycles of yellow fever.", "content": "Experiments with various Colombian marsupials and primates in laboratory cycles of yellow fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996628"}
{"pmid": "20996630", "title": "The dispersal of Aedes albopictus in the territory of Hawaii.", "content": "The dispersal of Aedes albopictus in the territory of Hawaii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996630"}
{"pmid": "20996631", "title": "Studies on imported malarias; transmission of foreign Plasmodium vivax by Anopheles quadrimaculatus.", "content": "Studies on imported malarias; transmission of foreign Plasmodium vivax by Anopheles quadrimaculatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996631"}
{"pmid": "20996632", "title": "Penicillin therapy in relapsing fever.", "content": "Penicillin therapy in relapsing fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996632"}
{"pmid": "20996634", "title": "Intestinal helminthiasis; clinical survey of 618 cases of infection with common intestinal helminths in children.", "content": "Intestinal helminthiasis; clinical survey of 618 cases of infection with common intestinal helminths in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996634"}
{"pmid": "20996635", "title": "An efficient concentration method (AEX) for detecting helminthic ova in feces (modification of the Telemann technic).", "content": "An efficient concentration method (AEX) for detecting helminthic ova in feces (modification of the Telemann technic).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996635"}
{"pmid": "20996633", "title": "A mild exanthematous disease seen in the Schouten Islands.", "content": "A mild exanthematous disease seen in the Schouten Islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996633"}
{"pmid": "20996636", "title": "Opportunities for training and research in tropical medicine and public health in Mexico.", "content": "Opportunities for training and research in tropical medicine and public health in Mexico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996636"}
{"pmid": "20996637", "title": "Heat rash as a problem in the naval service.", "content": "Heat rash as a problem in the naval service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996637"}
{"pmid": "20996638", "title": "Indolent tuberculosis.", "content": "Indolent tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996638"}
{"pmid": "20996640", "title": "SURVEY of the cases of phthisis on a clinic register.", "content": "SURVEY of the cases of phthisis on a clinic register.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996640"}
{"pmid": "20996639", "title": "The management of pneumoperitoneum therapy and peritoneoscopy.", "content": "The management of pneumoperitoneum therapy and peritoneoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996639"}
{"pmid": "20996641", "title": "A national scheme for the rehabilitation of the tuberculous.", "content": "A national scheme for the rehabilitation of the tuberculous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996641"}
{"pmid": "20996642", "title": "The American Social Hygiene Association; some notes on the historical background, development and future opportunities of the national voluntary organization for social hygiene in the United States.", "content": "The American Social Hygiene Association; some notes on the historical background, development and future opportunities of the national voluntary organization for social hygiene in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996642"}
{"pmid": "20996643", "title": "PEACETIME relationships in venereal disease control; a working agreement between the Army, Navy, Coast Guard, the Federal Security Agency and the American Social Hygiene Association, 1946.", "content": "PEACETIME relationships in venereal disease control; a working agreement between the Army, Navy, Coast Guard, the Federal Security Agency and the American Social Hygiene Association, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996643"}
{"pmid": "20996644", "title": "The pathology of equine virus abortion.", "content": "The pathology of equine virus abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996644"}
{"pmid": "20996645", "title": "A concise investigation of fowl spirochetosis in Egypt.", "content": "A concise investigation of fowl spirochetosis in Egypt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996645"}
{"pmid": "20996646", "title": "The relation of animal diseases to public health.", "content": "The relation of animal diseases to public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996646"}
{"pmid": "20996647", "title": "Small animal surgery in a mixed practice.", "content": "Small animal surgery in a mixed practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996647"}
{"pmid": "20996648", "title": "Single injection specific treatment for foot rot in cattle.", "content": "Single injection specific treatment for foot rot in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996648"}
{"pmid": "20996649", "title": "Sodium iodide therapy in infectious equine encephalomyelitis.", "content": "Sodium iodide therapy in infectious equine encephalomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996649"}
{"pmid": "20996650", "title": "Observations regarding Salmonella choleraesuis (var. kunzendorf) septicemia in swine.", "content": "Observations regarding Salmonella choleraesuis (var. kunzendorf) septicemia in swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996650"}
{"pmid": "20996651", "title": "Lantana poisoning in cattle.", "content": "Lantana poisoning in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996651"}
{"pmid": "20996652", "title": "REPORT on infectious equine encephalomyelitis in the United States in 1945.", "content": "REPORT on infectious equine encephalomyelitis in the United States in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996652"}
{"pmid": "20996654", "title": "Pulmonary actinomycosis in swine.", "content": "Pulmonary actinomycosis in swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996654"}
{"pmid": "20996656", "title": "A case of histoplasmosis in a dog.", "content": "A case of histoplasmosis in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996656"}
{"pmid": "20996653", "title": "Primary splenic endothelial sarcoma in a dog.", "content": "Primary splenic endothelial sarcoma in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996653"}
{"pmid": "20996655", "title": "Trichomonas and hemoproteus infections and the experimental use of DDT in the control of ectoparasites in a flock of Signal Corps pigeons in the Territory of Hawaii.", "content": "Trichomonas and hemoproteus infections and the experimental use of DDT in the control of ectoparasites in a flock of Signal Corps pigeons in the Territory of Hawaii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996655"}
{"pmid": "20996658", "title": "An improved method of testing for botulinus toxin by the use of penicillin.", "content": "An improved method of testing for botulinus toxin by the use of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996658"}
{"pmid": "20996657", "title": "A case of bovine listerellosis in Pennsylvania.", "content": "A case of bovine listerellosis in Pennsylvania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996657"}
{"pmid": "20996659", "title": "Listerellosis in a Hereford cow.", "content": "Listerellosis in a Hereford cow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996659"}
{"pmid": "20996660", "title": "BIOTIN deficiency in pigs.", "content": "BIOTIN deficiency in pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996660"}
{"pmid": "20996661", "title": "CANNIBALISM in poultry; controlling cannibalism.", "content": "CANNIBALISM in poultry; controlling cannibalism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996661"}
{"pmid": "20996662", "title": "Registry of veterinary pathology.", "content": "Registry of veterinary pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996662"}
{"pmid": "20996663", "title": "Observations on the natural history of the Fresno kangaroo rat.", "content": "Observations on the natural history of the Fresno kangaroo rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996663"}
{"pmid": "20996664", "title": "Observations on the vampire bat with special reference to longevity in captivity.", "content": "Observations on the vampire bat with special reference to longevity in captivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996664"}
{"pmid": "20996665", "title": "Trapping the California ground squirrel.", "content": "Trapping the California ground squirrel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996665"}
{"pmid": "20996666", "title": "Notes on the comparative osteology of the bobcat and the house cat.", "content": "Notes on the comparative osteology of the bobcat and the house cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996666"}
{"pmid": "20996667", "title": "Plastic vials for storing small skulls.", "content": "Plastic vials for storing small skulls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996667"}
{"pmid": "20996668", "title": "A revision of the movements of the forearm in tetrapods.", "content": "A revision of the movements of the forearm in tetrapods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996668"}
{"pmid": "20996669", "title": "Sympathetic rami in man.", "content": "Sympathetic rami in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996669"}
{"pmid": "20996671", "title": "An experimental study of the regeneration of mammalian striped muscle.", "content": "An experimental study of the regeneration of mammalian striped muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996671"}
{"pmid": "20996670", "title": "The lymphatics of the synovial membrane.", "content": "The lymphatics of the synovial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996670"}
{"pmid": "20996672", "title": "Quantitative histology of Wallerian degeneration; nuclear population in rabbit sciatic nerve.", "content": "Quantitative histology of Wallerian degeneration; nuclear population in rabbit sciatic nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996672"}
{"pmid": "20996673", "title": "Quadricipital M. biceps brachii.", "content": "Quadricipital M. biceps brachii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996673"}
{"pmid": "20996674", "title": "Repair of fractures of the parietal bone in rats.", "content": "Repair of fractures of the parietal bone in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996674"}
{"pmid": "20996675", "title": "Migration processes during ontogeny with reference to the venous development in the dorsal body wall.", "content": "Migration processes during ontogeny with reference to the venous development in the dorsal body wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996675"}
{"pmid": "20996676", "title": "The early development of the sheep heart.", "content": "The early development of the sheep heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996676"}
{"pmid": "20996678", "title": "Movements of the first rib.", "content": "Movements of the first rib.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996678"}
{"pmid": "20996677", "title": "Correlated changes in nervous tissues in malformations of the central nervous system.", "content": "Correlated changes in nervous tissues in malformations of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996677"}
{"pmid": "20996679", "title": "Terminal degeneration in the frontal cortex of the rabbit following the interruption of afferent fibres.", "content": "Terminal degeneration in the frontal cortex of the rabbit following the interruption of afferent fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996679"}
{"pmid": "20996680", "title": "The prescapular lymph node of the ox and its relation to lymphatic drainage of the skin.", "content": "The prescapular lymph node of the ox and its relation to lymphatic drainage of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996680"}
{"pmid": "20996681", "title": "Bilateral anterior venae cavae in a lion cub.", "content": "Bilateral anterior venae cavae in a lion cub.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996681"}
{"pmid": "20996682", "title": "Movements of the tongue in swallowing.", "content": "Movements of the tongue in swallowing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996682"}
{"pmid": "20996683", "title": "Motor localization and the effects of nerve injury on the ventral horn cells of the spinal cord.", "content": "Motor localization and the effects of nerve injury on the ventral horn cells of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996683"}
{"pmid": "20996684", "title": "Some effects of pituitary adrenotropic hormone (PATH), extract of suprarenal cortex, and colchicine on the haemopoietic system.", "content": "Some effects of pituitary adrenotropic hormone (PATH), extract of suprarenal cortex, and colchicine on the haemopoietic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996684"}
{"pmid": "20996685", "title": "The growth cycle of the cells of the adrenal cortex in the adult rat.", "content": "The growth cycle of the cells of the adrenal cortex in the adult rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996685"}
{"pmid": "20996686", "title": "The blood supply and lymphatic drainage of tendons.", "content": "The blood supply and lymphatic drainage of tendons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996686"}
{"pmid": "20996687", "title": "The visual paths in a case of unilateral anophthalmia with special reference to the problem of crossed and uncrossed visual fibres.", "content": "The visual paths in a case of unilateral anophthalmia with special reference to the problem of crossed and uncrossed visual fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996687"}
{"pmid": "20996688", "title": "The early development of the corpus luteum in the mare.", "content": "The early development of the corpus luteum in the mare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996688"}
{"pmid": "20996689", "title": "Conjugation in Paramecium bursaria; nuclear phenomena in lethal conjugation between varieties.", "content": "Conjugation in Paramecium bursaria; nuclear phenomena in lethal conjugation between varieties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996689"}
{"pmid": "20996690", "title": "Oral breathing valves in fishes.", "content": "Oral breathing valves in fishes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996690"}
{"pmid": "20996691", "title": "The histology of anuran limb regeneration.", "content": "The histology of anuran limb regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996691"}
{"pmid": "20996692", "title": "Anesthesia in the surgical treatment of congenital pulmonic stenosis.", "content": "Anesthesia in the surgical treatment of congenital pulmonic stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996692"}
{"pmid": "20996693", "title": "Pontocaine-dextrose-ephedrine for spinal anesthesia.", "content": "Pontocaine-dextrose-ephedrine for spinal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996693"}
{"pmid": "20996695", "title": "Lethal hypothermia in dogs of various ages.", "content": "Lethal hypothermia in dogs of various ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996695"}
{"pmid": "20996694", "title": "The effect of pentothal alone and in combination with oxygen or nitrous oxide-oxygen on arterial blood gases.", "content": "The effect of pentothal alone and in combination with oxygen or nitrous oxide-oxygen on arterial blood gases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996694"}
{"pmid": "20996696", "title": "The use of curare for abdominal surgery in seriously injured patients.", "content": "The use of curare for abdominal surgery in seriously injured patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996696"}
{"pmid": "20996697", "title": "The question of cerium oxalate as a prophylactic against postoperative vomiting.", "content": "The question of cerium oxalate as a prophylactic against postoperative vomiting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996697"}
{"pmid": "20996699", "title": "The rotameter in anesthesia.", "content": "The rotameter in anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996699"}
{"pmid": "20996698", "title": "Stages and signs of pentothal anesthesia; physiologic basis.", "content": "Stages and signs of pentothal anesthesia; physiologic basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996698"}
{"pmid": "20996700", "title": "Regional anesthesia by the intravenous route (slight modification of Bier's method).", "content": "Regional anesthesia by the intravenous route (slight modification of Bier's method).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996700"}
{"pmid": "20996701", "title": "Atropine poisoning; a case report.", "content": "Atropine poisoning; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996701"}
{"pmid": "20996702", "title": "Concerning the action of prostigmine.", "content": "Concerning the action of prostigmine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996702"}
{"pmid": "20996703", "title": "Double tier arm support.", "content": "Double tier arm support.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996703"}
{"pmid": "20996707", "title": "A toxicological comparison of Derris and Lonchocarpus.", "content": "A toxicological comparison of Derris and Lonchocarpus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996707"}
{"pmid": "20996708", "title": "Effect of mineral composition and particle size in dispersants on toxicity of rotenone dusts.", "content": "Effect of mineral composition and particle size in dispersants on toxicity of rotenone dusts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996708"}
{"pmid": "20996709", "title": "Control of the sex ratio in Macrocentrus ancylivorus.", "content": "Control of the sex ratio in Macrocentrus ancylivorus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996709"}
{"pmid": "20996710", "title": "Insecticides applied to forest litter to control New Guinea chiggers.", "content": "Insecticides applied to forest litter to control New Guinea chiggers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996710"}
{"pmid": "20996711", "title": "DDT for insect control at Army installations in the Fourth Service Command.", "content": "DDT for insect control at Army installations in the Fourth Service Command.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996711"}
{"pmid": "20996705", "title": "An orientation with respect to members of the genus Bacillus pathogenic for insects.", "content": "An orientation with respect to members of the genus Bacillus pathogenic for insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996705"}
{"pmid": "20996704", "title": "Action of microörganisms on hydrocarbons.", "content": "Action of microörganisms on hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996704"}
{"pmid": "20996712", "title": "Effect of short contact with DDT residues on Anopheles gambiae.", "content": "Effect of short contact with DDT residues on Anopheles gambiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996712"}
{"pmid": "20996713", "title": "DDT to control insects affecting man.", "content": "DDT to control insects affecting man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996713"}
{"pmid": "20996714", "title": "DDT to control insect pests affecting livestock.", "content": "DDT to control insect pests affecting livestock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996714"}
{"pmid": "20996716", "title": "The mechanism of sex control in the honey bee.", "content": "The mechanism of sex control in the honey bee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996716"}
{"pmid": "20996715", "title": "Observations on tick repellents.", "content": "Observations on tick repellents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996715"}
{"pmid": "20996706", "title": "Chemical nature and biological specificity of the substance inducing transformation of pneumococcal types.", "content": "Chemical nature and biological specificity of the substance inducing transformation of pneumococcal types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996706"}
{"pmid": "20996717", "title": "DDT as a spot treatment for flies.", "content": "DDT as a spot treatment for flies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996717"}
{"pmid": "20996718", "title": "Normal offspring produced by moribund aphids treated with DDT.", "content": "Normal offspring produced by moribund aphids treated with DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996718"}
{"pmid": "20996719", "title": "Desiccators as constant humidity chambers.", "content": "Desiccators as constant humidity chambers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996719"}
{"pmid": "20996720", "title": "Distribution records for mosquitoes of the southeastern states in 1945.", "content": "Distribution records for mosquitoes of the southeastern states in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996720"}
{"pmid": "20996721", "title": "DDT to control the relapsing fever tick.", "content": "DDT to control the relapsing fever tick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996721"}
{"pmid": "20996722", "title": "Use of calcium cyanide solutions in HCN toxicity experiments with insects.", "content": "Use of calcium cyanide solutions in HCN toxicity experiments with insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996722"}
{"pmid": "20996723", "title": "DDT to control rat fleas.", "content": "DDT to control rat fleas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996723"}
{"pmid": "20996724", "title": "Effects of oral dosages of DDT on certain vertebrates.", "content": "Effects of oral dosages of DDT on certain vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996724"}
{"pmid": "20996725", "title": "Gynandromorphism in Culex nigripalpus.", "content": "Gynandromorphism in Culex nigripalpus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996725"}
{"pmid": "20996726", "title": "DDT to control cat and dog fleas and dog lice.", "content": "DDT to control cat and dog fleas and dog lice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996726"}
{"pmid": "20996727", "title": "DDT for the control of Triatoma.", "content": "DDT for the control of Triatoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996727"}
{"pmid": "20996728", "title": "A new record of Anopheles albimanus in Texas.", "content": "A new record of Anopheles albimanus in Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996728"}
{"pmid": "20996729", "title": "The antimalarial activity of metachloridine (2-meta-anilamido-5-chloropyrimidine) and other metanilamide derivatives in test infections with P1 asmodium gallinaceum.", "content": "The antimalarial activity of metachloridine (2-meta-anilamido-5-chloropyrimidine) and other metanilamide derivatives in test infections with P1 asmodium gallinaceum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996729"}
{"pmid": "20996730", "title": "The prevention of sporozoite-induced infections of Plasmodium cathemerium in the canary by metachloridine.", "content": "The prevention of sporozoite-induced infections of Plasmodium cathemerium in the canary by metachloridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996730"}
{"pmid": "20996731", "title": "Plasmodium circumflexum (Kikuth) in ruffed grouse in Ontario.", "content": "Plasmodium circumflexum (Kikuth) in ruffed grouse in Ontario.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996731"}
{"pmid": "20996732", "title": "Migration of Endamoeba histolytica on solid media.", "content": "Migration of Endamoeba histolytica on solid media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996732"}
{"pmid": "20996733", "title": "An exceptional case of oxyuriasis of the intestinal wall.", "content": "An exceptional case of oxyuriasis of the intestinal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996733"}
{"pmid": "20996734", "title": "Further studies on distribution of schistosomiasis japonica in Szechwan Province, China.", "content": "Further studies on distribution of schistosomiasis japonica in Szechwan Province, China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996734"}
{"pmid": "20996735", "title": "Studies in trypanosomiasis.", "content": "Studies in trypanosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996735"}
{"pmid": "20996736", "title": "Studies in trypanosomiasis; the serum potassium levels of rats during infection with Trypanosoma lewisi, Trypanosoma brucei, and Trypanosoma equiperdum.", "content": "Studies in trypanosomiasis; the serum potassium levels of rats during infection with Trypanosoma lewisi, Trypanosoma brucei, and Trypanosoma equiperdum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996736"}
{"pmid": "20996737", "title": "Studies in trypanosomiasis; the plasma, whole blood and erythrocyte potassium of rats during the course of infection with Trypanosoma brucei and Trypanosoma equiperdum.", "content": "Studies in trypanosomiasis; the plasma, whole blood and erythrocyte potassium of rats during the course of infection with Trypanosoma brucei and Trypanosoma equiperdum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996737"}
{"pmid": "20996738", "title": "Studies in trypanosomiasis; the fragility of the erythrocytes in rats during the course of infection with Trypanosoma lewisi, Trypanosoma brucei and Trypanosoma equiperdum.", "content": "Studies in trypanosomiasis; the fragility of the erythrocytes in rats during the course of infection with Trypanosoma lewisi, Trypanosoma brucei and Trypanosoma equiperdum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996738"}
{"pmid": "20996739", "title": "Studies on the life history and development of Macracanthorhynchus ingens Meyer, 1933, with a redescription of the adult worm.", "content": "Studies on the life history and development of Macracanthorhynchus ingens Meyer, 1933, with a redescription of the adult worm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996739"}
{"pmid": "20996740", "title": "Specific soluble antigen in the blood of filarial patients.", "content": "Specific soluble antigen in the blood of filarial patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996740"}
{"pmid": "20996741", "title": "A new species of Rhopalopsyllus Baker (Siphonaptera) from Texas.", "content": "A new species of Rhopalopsyllus Baker (Siphonaptera) from Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996741"}
{"pmid": "20996742", "title": "The endogenous phase of the life cycle of Eimeria bovis.", "content": "The endogenous phase of the life cycle of Eimeria bovis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996742"}
{"pmid": "20996743", "title": "Benedenia noblei, a new monogenetic trematode of the Pacific Coast rock fish.", "content": "Benedenia noblei, a new monogenetic trematode of the Pacific Coast rock fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996743"}
{"pmid": "20996744", "title": "A technique for xenodiagnosis of filariasis.", "content": "A technique for xenodiagnosis of filariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996744"}
{"pmid": "20996751", "title": "Transplantability and presence of virus in spontaneous sarcomas and fibromas of chickens in relation to the age of the tumor-bearing animal.", "content": "Transplantability and presence of virus in spontaneous sarcomas and fibromas of chickens in relation to the age of the tumor-bearing animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996751"}
{"pmid": "20996752", "title": "A study of five transplantable chicken sarcomas induced by viruses.", "content": "A study of five transplantable chicken sarcomas induced by viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996752"}
{"pmid": "20996753", "title": "On the transplantability of lymphoid tumors, embryonal nephromas and carcinomas of chickens.", "content": "On the transplantability of lymphoid tumors, embryonal nephromas and carcinomas of chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996753"}
{"pmid": "20996754", "title": "Some effects of aromatic hydrocarbons on sulfur metabolism and tumor induction in mice.", "content": "Some effects of aromatic hydrocarbons on sulfur metabolism and tumor induction in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996754"}
{"pmid": "20996745", "title": "Studies on the structure of Streptomyces griseus.", "content": "Studies on the structure of Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996745"}
{"pmid": "20996755", "title": "Stimulation and retardation of neoplastic growth by sulfhydryl compounds.", "content": "Stimulation and retardation of neoplastic growth by sulfhydryl compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996755"}
{"pmid": "20996756", "title": "Effect of fresh milk on the production of hepatic tumors in rats by dimethylaminoazobenzene.", "content": "Effect of fresh milk on the production of hepatic tumors in rats by dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996756"}
{"pmid": "20996746", "title": "Biologic strains of Streptomyces griseus.", "content": "Biologic strains of Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996746"}
{"pmid": "20996757", "title": "The water content in the epidermis of mice undergoing carcinogenesis by methylcholanthrene.", "content": "The water content in the epidermis of mice undergoing carcinogenesis by methylcholanthrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996757"}
{"pmid": "20996758", "title": "Tubular adenomas and testis-like tubules of the ovaries of aged rats.", "content": "Tubular adenomas and testis-like tubules of the ovaries of aged rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996758"}
{"pmid": "20996759", "title": "On Einthoven's triangle, the theory of unipolar electrocardiographic leads, and the interpretation of the precordial electrocardiogram.", "content": "On Einthoven's triangle, the theory of unipolar electrocardiographic leads, and the interpretation of the precordial electrocardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996759"}
{"pmid": "20996760", "title": "The effect of salicylates on acute rheumatic fever.", "content": "The effect of salicylates on acute rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996760"}
{"pmid": "20996761", "title": "A refractory case of subacute bacterial endocarditis due to Veillonella gazogenes clinically arrested by a combination of penicillin, sodium paraaminohippurate, and heparin.", "content": "A refractory case of subacute bacterial endocarditis due to Veillonella gazogenes clinically arrested by a combination of penicillin, sodium paraaminohippurate, and heparin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996761"}
{"pmid": "20996762", "title": "Cardiac output in heart failure.", "content": "Cardiac output in heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996762"}
{"pmid": "20996763", "title": "Renin in essential hypertension.", "content": "Renin in essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996763"}
{"pmid": "20996764", "title": "Parasternal leads in tricuspid insufficiency.", "content": "Parasternal leads in tricuspid insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996764"}
{"pmid": "20996765", "title": "Persistence of the juvenile pattern in the precordial leads of healthy adult Negroes, with report of electrocardiographic survey on three hundred Negro and two hundred white subjects.", "content": "Persistence of the juvenile pattern in the precordial leads of healthy adult Negroes, with report of electrocardiographic survey on three hundred Negro and two hundred white subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996765"}
{"pmid": "20996766", "title": "Electrocardiographic changes occurring during upper respiratory infections.", "content": "Electrocardiographic changes occurring during upper respiratory infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996766"}
{"pmid": "20996767", "title": "Cor biloculare.", "content": "Cor biloculare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996767"}
{"pmid": "20996769", "title": "Growth and transformation of the mandibular joint in the rat; hypophysectomized female rats.", "content": "Growth and transformation of the mandibular joint in the rat; hypophysectomized female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996769"}
{"pmid": "20996768", "title": "Growth and transformation of the mandibular joint in the rat.", "content": "Growth and transformation of the mandibular joint in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996768"}
{"pmid": "20996770", "title": "Growth and transformation of the mandibular joint in the rat; the effect of growth hormone and thyroxin injections in hypophysectomized female rats.", "content": "Growth and transformation of the mandibular joint in the rat; the effect of growth hormone and thyroxin injections in hypophysectomized female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996770"}
{"pmid": "20996771", "title": "The effects of a single massive dose of vitamin D2 (D-Stoss therapy) on oral and other tissues of young dogs.", "content": "The effects of a single massive dose of vitamin D2 (D-Stoss therapy) on oral and other tissues of young dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996771"}
{"pmid": "20996773", "title": "Oral prosthesis in the repair of war injuries.", "content": "Oral prosthesis in the repair of war injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996773"}
{"pmid": "20996772", "title": "Changes in oral structures of the dog persisting after chronic overdoses of vitamin D.", "content": "Changes in oral structures of the dog persisting after chronic overdoses of vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996772"}
{"pmid": "20996774", "title": "Classification and treatment of the rheumatic diseases with special emphasis on infectious and rheumatoid arthritis.", "content": "Classification and treatment of the rheumatic diseases with special emphasis on infectious and rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996774"}
{"pmid": "20996775", "title": "The physiology of water in health.", "content": "The physiology of water in health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996775"}
{"pmid": "20996776", "title": "The physiology of water in disease.", "content": "The physiology of water in disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996776"}
{"pmid": "20996777", "title": "The investigation of psychosomatic mechanisms in dental patients.", "content": "The investigation of psychosomatic mechanisms in dental patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996777"}
{"pmid": "20996778", "title": "The effect of heat-processed foods and metabolized vitamin D milk on the dentofacial structures of experimental animals.", "content": "The effect of heat-processed foods and metabolized vitamin D milk on the dentofacial structures of experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996778"}
{"pmid": "20996780", "title": "Growth of the child and the calcification pattern of the teeth.", "content": "Growth of the child and the calcification pattern of the teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996780"}
{"pmid": "20996779", "title": "Nutrition in action.", "content": "Nutrition in action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996779"}
{"pmid": "20996781", "title": "The treatment of malocclusion with and without the removal of dental units.", "content": "The treatment of malocclusion with and without the removal of dental units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996781"}
{"pmid": "20996782", "title": "The family and dental disease; age of parents and dental caries (DMF) experience in offspring.", "content": "The family and dental disease; age of parents and dental caries (DMF) experience in offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996782"}
{"pmid": "20996783", "title": "The family and dental disease; size of family and dental caries (DMF) experience in offspring.", "content": "The family and dental disease; size of family and dental caries (DMF) experience in offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996783"}
{"pmid": "20996784", "title": "The Army Institute of Pathology and the Registry of Dental and Oral Pathology.", "content": "The Army Institute of Pathology and the Registry of Dental and Oral Pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996784"}
{"pmid": "20996785", "title": "An evaluation of the biopsy as a diagnostic aid.", "content": "An evaluation of the biopsy as a diagnostic aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996785"}
{"pmid": "20996786", "title": "The histogenesis of the cementoma.", "content": "The histogenesis of the cementoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996786"}
{"pmid": "20996787", "title": "Invasion of paranasal sinuses by tumors of meningeal origin.", "content": "Invasion of paranasal sinuses by tumors of meningeal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996787"}
{"pmid": "20996788", "title": "Eosinophilic granuloma of bone with primary oral manifestations.", "content": "Eosinophilic granuloma of bone with primary oral manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996788"}
{"pmid": "20996789", "title": "Fibrous dysplasia (ossifying fibroma) of the maxilla and mandible.", "content": "Fibrous dysplasia (ossifying fibroma) of the maxilla and mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996789"}
{"pmid": "20996790", "title": "Intracranial epidermoids (cholesteatomas).", "content": "Intracranial epidermoids (cholesteatomas).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996790"}
{"pmid": "20996791", "title": "Caries of the enamel.", "content": "Caries of the enamel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996791"}
{"pmid": "20996792", "title": "Certification of specialists.", "content": "Certification of specialists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996792"}
{"pmid": "20996793", "title": "Why do we have dental journals?", "content": "Why do we have dental journals?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996793"}
{"pmid": "20996794", "title": "Dental journalism twenty-five years ago.", "content": "Dental journalism twenty-five years ago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996794"}
{"pmid": "20996795", "title": "The need of a current index to dental serial publications including allied fields.", "content": "The need of a current index to dental serial publications including allied fields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996795"}
{"pmid": "20996796", "title": "Fundamentals of graduate education.", "content": "Fundamentals of graduate education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996796"}
{"pmid": "20996797", "title": "Dental education and dental personnel.", "content": "Dental education and dental personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996797"}
{"pmid": "20996798", "title": "The need for clinical applications of anatomy in dentistry.", "content": "The need for clinical applications of anatomy in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996798"}
{"pmid": "20996799", "title": "The microbic flora of the dental plaque in relation to the beginning of caries.", "content": "The microbic flora of the dental plaque in relation to the beginning of caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996799"}
{"pmid": "20996800", "title": "Preliminary reports on the effect on dental caries of the use of sodium fluoride in a prophylactic cleaning mixture and in a mouthwash.", "content": "Preliminary reports on the effect on dental caries of the use of sodium fluoride in a prophylactic cleaning mixture and in a mouthwash.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996800"}
{"pmid": "20996801", "title": "The buffer capacity of saliva as a measure of dental caries activity.", "content": "The buffer capacity of saliva as a measure of dental caries activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996801"}
{"pmid": "20996803", "title": "Chemical studies in periodontal disease; putrefaction of salivary proteins.", "content": "Chemical studies in periodontal disease; putrefaction of salivary proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996803"}
{"pmid": "20996802", "title": "Studies of the effect of glycerite of hydrogen peroxide upon the numbers of oral microorganisms.", "content": "Studies of the effect of glycerite of hydrogen peroxide upon the numbers of oral microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996802"}
{"pmid": "20996805", "title": "Myoblastoma.", "content": "Myoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996805"}
{"pmid": "20996804", "title": "Blood studies in periodontoclasia.", "content": "Blood studies in periodontoclasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996804"}
{"pmid": "20996806", "title": "Eosinophilic granuloma.", "content": "Eosinophilic granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996806"}
{"pmid": "20996807", "title": "Human saliva; relationship of total calcium to inorganic phosphorus of resting saliva.", "content": "Human saliva; relationship of total calcium to inorganic phosphorus of resting saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996807"}
{"pmid": "20996808", "title": "Human saliva; relationship of total calcium and inorganic phosphorus to rate of flow of resting saliva.", "content": "Human saliva; relationship of total calcium and inorganic phosphorus to rate of flow of resting saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996808"}
{"pmid": "20996809", "title": "Human saliva; is there a seasonal influence on rate of flow and calcium and phosphorus content of resting saliva?", "content": "Human saliva; is there a seasonal influence on rate of flow and calcium and phosphorus content of resting saliva?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996809"}
{"pmid": "20996821", "title": "Chromoblastomycosis.", "content": "Chromoblastomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996821"}
{"pmid": "20996820", "title": "Use of penicillin in the treatment of syphilis in pregnancy.", "content": "Use of penicillin in the treatment of syphilis in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996820"}
{"pmid": "20996822", "title": "Rat mite dermatitis; acariasis caused by the tropical rat mite, Liponyssus bacoti Hirst.", "content": "Rat mite dermatitis; acariasis caused by the tropical rat mite, Liponyssus bacoti Hirst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996822"}
{"pmid": "20996823", "title": "Urinary excretion of porphyrin in dermatoses.", "content": "Urinary excretion of porphyrin in dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996823"}
{"pmid": "20996824", "title": "Allergic dermatoses complicating penicillin therapy.", "content": "Allergic dermatoses complicating penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996824"}
{"pmid": "20996825", "title": "In vitro fungistasis by a Bacterium (Bacillus subtilis var. XG and XY).", "content": "In vitro fungistasis by a Bacterium (Bacillus subtilis var. XG and XY).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996825"}
{"pmid": "20996826", "title": "Relation of quinacrine hydrochloride to lichenoid dermatitis (atypical lichen planus).", "content": "Relation of quinacrine hydrochloride to lichenoid dermatitis (atypical lichen planus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996826"}
{"pmid": "20996827", "title": "Complications of lichenoid dermatitis; glomerulonephritis and severe pigmentary changes in the exfoliative state of lichenoid dermatitis.", "content": "Complications of lichenoid dermatitis; glomerulonephritis and severe pigmentary changes in the exfoliative state of lichenoid dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996827"}
{"pmid": "20996828", "title": "Exfoliative dermatitis due to polyvalent arsenical sensitivity.", "content": "Exfoliative dermatitis due to polyvalent arsenical sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996828"}
{"pmid": "20996829", "title": "Cutaneous leishmaniasis (Oriental sore); report of autochthonous cases observed in Haifa.", "content": "Cutaneous leishmaniasis (Oriental sore); report of autochthonous cases observed in Haifa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996829"}
{"pmid": "20996830", "title": "Dermatitis due to quinacrine hydrochloride.", "content": "Dermatitis due to quinacrine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996830"}
{"pmid": "20996831", "title": "An illuminating magnifier for the reading of the rapid test for syphilis.", "content": "An illuminating magnifier for the reading of the rapid test for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996831"}
{"pmid": "20996832", "title": "A case for diagnosis (deep fungous infection?).", "content": "A case for diagnosis (deep fungous infection?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996832"}
{"pmid": "20996833", "title": "Dermatitis herpetiformis occurring in twins.", "content": "Dermatitis herpetiformis occurring in twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996833"}
{"pmid": "20996834", "title": "Hyperkeratosis follicularis and parafollicularis in cutem penetrans (Kyrle's disease).", "content": "Hyperkeratosis follicularis and parafollicularis in cutem penetrans (Kyrle's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996834"}
{"pmid": "20996835", "title": "Pityriasis lichenoides et varioliformis acuta.", "content": "Pityriasis lichenoides et varioliformis acuta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996835"}
{"pmid": "20996836", "title": "Scleroderma, circumscribed.", "content": "Scleroderma, circumscribed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996836"}
{"pmid": "20996837", "title": "Herpes gestationis.", "content": "Herpes gestationis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996837"}
{"pmid": "20996838", "title": "Neurodermatitis with the histologic picture of mycosis fungoides.", "content": "Neurodermatitis with the histologic picture of mycosis fungoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996838"}
{"pmid": "20996839", "title": "Multiple benign cystic epithelioma.", "content": "Multiple benign cystic epithelioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996839"}
{"pmid": "20996840", "title": "Infectious eczematoid dermatitis.", "content": "Infectious eczematoid dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996840"}
{"pmid": "20996842", "title": "Angiolupoid of Brocq and Pautrier.", "content": "Angiolupoid of Brocq and Pautrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996842"}
{"pmid": "20996841", "title": "Dermatitis medicamentosa (quinacrine?).", "content": "Dermatitis medicamentosa (quinacrine?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996841"}
{"pmid": "20996844", "title": "Cutaneous scopulariopsosis.", "content": "Cutaneous scopulariopsosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996844"}
{"pmid": "20996843", "title": "Leprosy, tuberculoid type.", "content": "Leprosy, tuberculoid type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996843"}
{"pmid": "20996845", "title": "Exudative discoid lichenoid chronic dermatitis.", "content": "Exudative discoid lichenoid chronic dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996845"}
{"pmid": "20996863", "title": "Differences in excretion of hippuric acid and glucuronates after ingestion of sodium benzoate and benzoic acid.", "content": "Differences in excretion of hippuric acid and glucuronates after ingestion of sodium benzoate and benzoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996863"}
{"pmid": "20996864", "title": "Roentgenological evidence of appendiceal abscesses.", "content": "Roentgenological evidence of appendiceal abscesses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996864"}
{"pmid": "20996865", "title": "The fasting gastric contents as an index of gastric functioning.", "content": "The fasting gastric contents as an index of gastric functioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996865"}
{"pmid": "20996866", "title": "Gastroscopy as an aid to diagnosis of gastric disorders.", "content": "Gastroscopy as an aid to diagnosis of gastric disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996866"}
{"pmid": "20996867", "title": "Observations on percussion of the liver in acute infectious hepatitis.", "content": "Observations on percussion of the liver in acute infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996867"}
{"pmid": "20996868", "title": "Idiopathic and psychogenic incontinentia recti.", "content": "Idiopathic and psychogenic incontinentia recti.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996868"}
{"pmid": "20996869", "title": "The causes and mechanisms of abdominal pain.", "content": "The causes and mechanisms of abdominal pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996869"}
{"pmid": "20996870", "title": "The president's address.", "content": "The president's address.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996870"}
{"pmid": "20996871", "title": "Military gastro-enterology; the summing up.", "content": "Military gastro-enterology; the summing up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996871"}
{"pmid": "20996872", "title": "The differential diagnosis of 207 hospitalized cases of peptic ulcer.", "content": "The differential diagnosis of 207 hospitalized cases of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996872"}
{"pmid": "20996873", "title": "Correlated gastroscopic and psychiatric studies of soldiers with chronic non-ulcerative dyspepsia.", "content": "Correlated gastroscopic and psychiatric studies of soldiers with chronic non-ulcerative dyspepsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996873"}
{"pmid": "20996874", "title": "Clinical findings in American soldiers released from a German prison camp.", "content": "Clinical findings in American soldiers released from a German prison camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996874"}
{"pmid": "20996875", "title": "Gastro-intestinal bleeding in hereditary hemorrhagic telangiectasia; historical review and case report with gastroscopic findings and rutin therapy.", "content": "Gastro-intestinal bleeding in hereditary hemorrhagic telangiectasia; historical review and case report with gastroscopic findings and rutin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996875"}
{"pmid": "20996876", "title": "The effects of beta-dimethylaminoethyl benzilate hydrochloride on intestinal activity.", "content": "The effects of beta-dimethylaminoethyl benzilate hydrochloride on intestinal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996876"}
{"pmid": "20996877", "title": "The effect of glucose on the motility of the stomach and small intestine.", "content": "The effect of glucose on the motility of the stomach and small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996877"}
{"pmid": "20996878", "title": "The effect of pilocarpine on mucus secretion by the pyloric mucosa.", "content": "The effect of pilocarpine on mucus secretion by the pyloric mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996878"}
{"pmid": "20996879", "title": "Hematemesis associated with gastric arteriosclerosis.", "content": "Hematemesis associated with gastric arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996879"}
{"pmid": "20996880", "title": "Puzzling nervous storms due to food allergy.", "content": "Puzzling nervous storms due to food allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996880"}
{"pmid": "20996881", "title": "[Thrombosis of the superior mesenteric vein; intestinal branches].", "content": "[Thrombosis of the superior mesenteric vein; intestinal branches].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996881"}
{"pmid": "20996884", "title": "Inhibitors of hyaluronidase in blood sera and their effect of follicle cell dispersal.", "content": "Inhibitors of hyaluronidase in blood sera and their effect of follicle cell dispersal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996884"}
{"pmid": "20996886", "title": "The experimental production of menstrual anomalies.", "content": "The experimental production of menstrual anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996886"}
{"pmid": "20996885", "title": "Effect of purified gonadotropes on the androgen-secreting ability of testes of hypophysectomized cocks.", "content": "Effect of purified gonadotropes on the androgen-secreting ability of testes of hypophysectomized cocks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996885"}
{"pmid": "20996887", "title": "The weaning guinea pig as test object for estrogen assays.", "content": "The weaning guinea pig as test object for estrogen assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996887"}
{"pmid": "20996888", "title": "Excretion of urinary corticoids and 17-ketosteroids in the normal individual.", "content": "Excretion of urinary corticoids and 17-ketosteroids in the normal individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996888"}
{"pmid": "20996889", "title": "The disturbance in iodine metabolism produced by thiocyanate; the mechanism of its goitrogenic action with radioactive iodine as indicator.", "content": "The disturbance in iodine metabolism produced by thiocyanate; the mechanism of its goitrogenic action with radioactive iodine as indicator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996889"}
{"pmid": "20996890", "title": "The influence of ingested estrogens on feed intake, metabolic rate and lipemia in male fowl.", "content": "The influence of ingested estrogens on feed intake, metabolic rate and lipemia in male fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996890"}
{"pmid": "20996891", "title": "Estrogens and the sex skin in the male chimpanzee.", "content": "Estrogens and the sex skin in the male chimpanzee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996891"}
{"pmid": "20996892", "title": "Effects of propylthiouracil and of potassium thiocyanate on the uptake of iodine by the thyroid gland of the rat.", "content": "Effects of propylthiouracil and of potassium thiocyanate on the uptake of iodine by the thyroid gland of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996892"}
{"pmid": "20996893", "title": "Clinical method for the chromatographic-colorimetric determination of urinary 17-ketosteroids.", "content": "Clinical method for the chromatographic-colorimetric determination of urinary 17-ketosteroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996893"}
{"pmid": "20996894", "title": "Testosterone propionate therapy in one hundred cases of angina pectoris.", "content": "Testosterone propionate therapy in one hundred cases of angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996894"}
{"pmid": "20996895", "title": "Addison's disease in an infant.", "content": "Addison's disease in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996895"}
{"pmid": "20996896", "title": "Metabolic studies in children fed milk from cows receiving synthetic thyroprotein.", "content": "Metabolic studies in children fed milk from cows receiving synthetic thyroprotein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996896"}
{"pmid": "20996897", "title": "Therapeutic use of testosterone in aqueous suspension.", "content": "Therapeutic use of testosterone in aqueous suspension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996897"}
{"pmid": "20996898", "title": "Hereditary exophthalmic goitre; report of eleven cases in one family.", "content": "Hereditary exophthalmic goitre; report of eleven cases in one family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996898"}
{"pmid": "20996899", "title": "Goiter.", "content": "Goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996899"}
{"pmid": "20996908", "title": "Organised medical care in Chile.", "content": "Organised medical care in Chile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996908"}
{"pmid": "20996909", "title": "What industry expects of medicine.", "content": "What industry expects of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996909"}
{"pmid": "20996910", "title": "Noxious vapors in aircraft cabins.", "content": "Noxious vapors in aircraft cabins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996910"}
{"pmid": "20996911", "title": "Personality components in employment problems.", "content": "Personality components in employment problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996911"}
{"pmid": "20996912", "title": "Controlled nuclear energy; its attendant hazards and benefits.", "content": "Controlled nuclear energy; its attendant hazards and benefits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996912"}
{"pmid": "20996913", "title": "Atomic disintegration.", "content": "Atomic disintegration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996913"}
{"pmid": "20996918", "title": "Alcohol problems dissected.", "content": "Alcohol problems dissected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996918"}
{"pmid": "20996919", "title": "DAKAR yellow fever vaccine.", "content": "DAKAR yellow fever vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996919"}
{"pmid": "20996921", "title": "WORLD Health Organization.", "content": "WORLD Health Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996921"}
{"pmid": "20996920", "title": "The typhus-relapsing fever association.", "content": "The typhus-relapsing fever association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996920"}
{"pmid": "20996933", "title": "The classification of leprosy.", "content": "The classification of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996933"}
{"pmid": "20996935", "title": "SOUTH American classification of leprosy.", "content": "SOUTH American classification of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996935"}
{"pmid": "20996937", "title": "Testosterone in angina pectoris.", "content": "Testosterone in angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996937"}
{"pmid": "20996936", "title": "The spermatogenic activity of delta 5-pregnenolone and of its esters.", "content": "The spermatogenic activity of delta 5-pregnenolone and of its esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996936"}
{"pmid": "20996938", "title": "Echinococcosis in Iceland.", "content": "Echinococcosis in Iceland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996938"}
{"pmid": "20996939", "title": "Traumatic streptococcic meningitis; report of a case with recovery and review of literature.", "content": "Traumatic streptococcic meningitis; report of a case with recovery and review of literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996939"}
{"pmid": "20996934", "title": "Some observations on the role of allergy in leprosy.", "content": "Some observations on the role of allergy in leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996934"}
{"pmid": "20996940", "title": "Pneumonitis ocurring in rheumatic fever.", "content": "Pneumonitis ocurring in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996940"}
{"pmid": "20996923", "title": "Studies with Coccidioides immitis.", "content": "Studies with Coccidioides immitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996923"}
{"pmid": "20996941", "title": "Selection of patients with arterial hypertension for treatment by repeated injections of pitressin.", "content": "Selection of patients with arterial hypertension for treatment by repeated injections of pitressin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996941"}
{"pmid": "20996924", "title": "Studies with Coccidioides immitis; in vitro effects of streptothricin and streptomycin.", "content": "Studies with Coccidioides immitis; in vitro effects of streptothricin and streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996924"}
{"pmid": "20996922", "title": "Infections with Plasmodium gallinaceum in chick embryos induced by exoerythrocytic and blood stages.", "content": "Infections with Plasmodium gallinaceum in chick embryos induced by exoerythrocytic and blood stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996922"}
{"pmid": "20996942", "title": "Reactions to intravenously administered amino acids (casein hydrolysates).", "content": "Reactions to intravenously administered amino acids (casein hydrolysates).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996942"}
{"pmid": "20996925", "title": "Storage of mouse-adapted strains of poliomyelitis virus and of Japanese B encephalitis virus at subfreezing temperatures.", "content": "Storage of mouse-adapted strains of poliomyelitis virus and of Japanese B encephalitis virus at subfreezing temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996925"}
{"pmid": "20996926", "title": "The problem of the dangerous carrier of hemolytic streptococci; observations upon the role of the hands, of blowing the nose, of sneezing, and of coughing in the dispersal of these microorganisms.", "content": "The problem of the dangerous carrier of hemolytic streptococci; observations upon the role of the hands, of blowing the nose, of sneezing, and of coughing in the dispersal of these microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996926"}
{"pmid": "20996927", "title": "The fungicidal action of triethylene glycol.", "content": "The fungicidal action of triethylene glycol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996927"}
{"pmid": "20996930", "title": "A hemolytic corynebacterium resembling Corynebacterium ovis and Corynebacterium pyogenes in man.", "content": "A hemolytic corynebacterium resembling Corynebacterium ovis and Corynebacterium pyogenes in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996930"}
{"pmid": "20996928", "title": "An outbreak of gastroenteritis presumably caused by Salmonella pullorum.", "content": "An outbreak of gastroenteritis presumably caused by Salmonella pullorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996928"}
{"pmid": "20996929", "title": "Effect of time of contact at 37 C and hydrogen ion concentration on the degree of neutralization of equine encephalomyelitis virus (Eastern type) by immune serum.", "content": "Effect of time of contact at 37 C and hydrogen ion concentration on the degree of neutralization of equine encephalomyelitis virus (Eastern type) by immune serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996929"}
{"pmid": "20996944", "title": "Purpura as a complication of malaria.", "content": "Purpura as a complication of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996944"}
{"pmid": "20996943", "title": "Malarial jaundice.", "content": "Malarial jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996943"}
{"pmid": "20996946", "title": "The urinary excretion of methionine in liver disorder.", "content": "The urinary excretion of methionine in liver disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996946"}
{"pmid": "20996931", "title": "Salmonella types of the Pacific area.", "content": "Salmonella types of the Pacific area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996931"}
{"pmid": "20996945", "title": "The blood protein tyrosine reaction in malaria, acute epidemic hepatitis, and certain other diseases.", "content": "The blood protein tyrosine reaction in malaria, acute epidemic hepatitis, and certain other diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996945"}
{"pmid": "20996947", "title": "The use of molybdenized ferrous sulfate in the treatment of true iron deficiency anemia of pregnancy.", "content": "The use of molybdenized ferrous sulfate in the treatment of true iron deficiency anemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996947"}
{"pmid": "20996932", "title": "Rapid agglutination test as a possible aid in the laboratory diagnosis of ornithosis.", "content": "Rapid agglutination test as a possible aid in the laboratory diagnosis of ornithosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996932"}
{"pmid": "20996948", "title": "The effect of methylxanthines on the prothrombin time and the coagulation of the blood.", "content": "The effect of methylxanthines on the prothrombin time and the coagulation of the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996948"}
{"pmid": "20996951", "title": "Schizophrenia.", "content": "Schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996951"}
{"pmid": "20996950", "title": "Infectious hepatitis.", "content": "Infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996950"}
{"pmid": "20996949", "title": "Blood levels of penicillin after various forms of oral administration.", "content": "Blood levels of penicillin after various forms of oral administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996949"}
{"pmid": "20996952", "title": "Direct measurement of coronary blood flow in the anesthetized dog.", "content": "Direct measurement of coronary blood flow in the anesthetized dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996952"}
{"pmid": "20996953", "title": "Phase-boundary potentials and the nerve impulse.", "content": "Phase-boundary potentials and the nerve impulse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996953"}
{"pmid": "20996954", "title": "The leukocytic response of patients with experimentally induced infectious hepatitis.", "content": "The leukocytic response of patients with experimentally induced infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996954"}
{"pmid": "20996955", "title": "Retroperitoneal splenomegaly; occurrence in a case of leukopenic plasma cell leukemia.", "content": "Retroperitoneal splenomegaly; occurrence in a case of leukopenic plasma cell leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996955"}
{"pmid": "20996956", "title": "A modified cephalin cholesterol test (Hanger) in the study of hepatic disease.", "content": "A modified cephalin cholesterol test (Hanger) in the study of hepatic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996956"}
{"pmid": "20996957", "title": "The effect of prostigmine (neostigmine) on the muscle spasm of rheumatoid arthritis.", "content": "The effect of prostigmine (neostigmine) on the muscle spasm of rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996957"}
{"pmid": "20996958", "title": "Melituria in healthy American men with special reference to transitory glycosuria.", "content": "Melituria in healthy American men with special reference to transitory glycosuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996958"}
{"pmid": "20996959", "title": "The reaction of the vessels of the mesentery and intestine to angiotonin and renin.", "content": "The reaction of the vessels of the mesentery and intestine to angiotonin and renin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996959"}
{"pmid": "20996960", "title": "Sulfapyrazine; its use in the prophylaxis of respiratory disease.", "content": "Sulfapyrazine; its use in the prophylaxis of respiratory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996960"}
{"pmid": "20996961", "title": "Vitamin levels in pernicious anemia.", "content": "Vitamin levels in pernicious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996961"}
{"pmid": "20996963", "title": "Capillary microscopy, with special reference to capillary petechiae.", "content": "Capillary microscopy, with special reference to capillary petechiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996963"}
{"pmid": "20996962", "title": "The use of a histamine antagonist, beta-dimethylaminethyl benzhydryl ether hydrochloride, in allergic disease.", "content": "The use of a histamine antagonist, beta-dimethylaminethyl benzhydryl ether hydrochloride, in allergic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996962"}
{"pmid": "20996964", "title": "Clinical and laboratory studies of liver function in therapeutic malaria.", "content": "Clinical and laboratory studies of liver function in therapeutic malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996964"}
{"pmid": "20996965", "title": "Effect of room temperature on sedimentation rate of red blood cells of man.", "content": "Effect of room temperature on sedimentation rate of red blood cells of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996965"}
{"pmid": "20996966", "title": "Aplastic anemia in soldiers treated with atabrine (quinacrine).", "content": "Aplastic anemia in soldiers treated with atabrine (quinacrine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996966"}
{"pmid": "20996967", "title": "Temporal arteritis and loss of vision.", "content": "Temporal arteritis and loss of vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996967"}
{"pmid": "20996969", "title": "Organizing hemothorax; a clinical entity.", "content": "Organizing hemothorax; a clinical entity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996969"}
{"pmid": "20996968", "title": "Pituitary-diabetes.", "content": "Pituitary-diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996968"}
{"pmid": "20996970", "title": "Folic acid (synthetic L. casei factor), an essential panhematopoietic stimulus.", "content": "Folic acid (synthetic L. casei factor), an essential panhematopoietic stimulus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996970"}
{"pmid": "20996971", "title": "Primary systemic amyloidosis; jaundice as a rare accompaniment.", "content": "Primary systemic amyloidosis; jaundice as a rare accompaniment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996971"}
{"pmid": "20996972", "title": "Positive reactions to the Kahn test for syphilis; their incidence and meaning in healthy American men.", "content": "Positive reactions to the Kahn test for syphilis; their incidence and meaning in healthy American men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996972"}
{"pmid": "20996973", "title": "Intestinal parasites diagnosed at an Army general hospital in the South Pacific.", "content": "Intestinal parasites diagnosed at an Army general hospital in the South Pacific.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996973"}
{"pmid": "20996974", "title": "Effect of graded doses of thyroxin on experimental goiters, induced by promizole.", "content": "Effect of graded doses of thyroxin on experimental goiters, induced by promizole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996974"}
{"pmid": "20996975", "title": "Note on hippuric acid synthesis in senility.", "content": "Note on hippuric acid synthesis in senility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996975"}
{"pmid": "20996977", "title": "Succinylsulfathiazole in the nutrition of the rat.", "content": "Succinylsulfathiazole in the nutrition of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996977"}
{"pmid": "20996976", "title": "The activity of penicillin in the intranasal pneumococcus infection of mice.", "content": "The activity of penicillin in the intranasal pneumococcus infection of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996976"}
{"pmid": "20996978", "title": "Effect of citrate on the reactions of lead with blood cells and plasma.", "content": "Effect of citrate on the reactions of lead with blood cells and plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996978"}
{"pmid": "20996979", "title": "Alteration of the electrocardiographic P waves in acute rheumatic fever.", "content": "Alteration of the electrocardiographic P waves in acute rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996979"}
{"pmid": "20996980", "title": "Evidence of maternal Rh sensitization without evidence of hemolytic disease in the newborn.", "content": "Evidence of maternal Rh sensitization without evidence of hemolytic disease in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996980"}
{"pmid": "20996981", "title": "Response to penicillin by a typhoid carrier; studies on penicillin sensitivity of strains of typhoid bacilli.", "content": "Response to penicillin by a typhoid carrier; studies on penicillin sensitivity of strains of typhoid bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996981"}
{"pmid": "20996982", "title": "Bacteriologic, clinical and pathologic experience with 86 sporadic cases of Salmonella infection.", "content": "Bacteriologic, clinical and pathologic experience with 86 sporadic cases of Salmonella infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996982"}
{"pmid": "20996983", "title": "Hookworm infections in troops returning from the Pacific.", "content": "Hookworm infections in troops returning from the Pacific.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996983"}
{"pmid": "20996984", "title": "Fibrocystic disease of the pancreas.", "content": "Fibrocystic disease of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996984"}
{"pmid": "20996985", "title": "Maternal disease as a principle in the epidemiology of congenital anomalies; with a review of rubella.", "content": "Maternal disease as a principle in the epidemiology of congenital anomalies; with a review of rubella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996985"}
{"pmid": "20996986", "title": "The problem of sterility today.", "content": "The problem of sterility today.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996986"}
{"pmid": "20996987", "title": "Testicular dysfunction; diagnosis and treatment.", "content": "Testicular dysfunction; diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996987"}
{"pmid": "20996988", "title": "The treatment of empyema with penicillin.", "content": "The treatment of empyema with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996988"}
{"pmid": "20996989", "title": "Clinical significance of hoarseness.", "content": "Clinical significance of hoarseness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996989"}
{"pmid": "20996990", "title": "Practical aspects of mammary disease in the female.", "content": "Practical aspects of mammary disease in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996990"}
{"pmid": "20996991", "title": "Child behavior problems and the physician in practice.", "content": "Child behavior problems and the physician in practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996991"}
{"pmid": "20996992", "title": "A community plan for the psychiatric treatment of veterans.", "content": "A community plan for the psychiatric treatment of veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996992"}
{"pmid": "20996993", "title": "Typhoid fever; a treatment failure with streptomycin.", "content": "Typhoid fever; a treatment failure with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996993"}
{"pmid": "20996994", "title": "Malignancy of the thyroid gland.", "content": "Malignancy of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996994"}
{"pmid": "20996995", "title": "Dental care for children.", "content": "Dental care for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996995"}
{"pmid": "20996998", "title": "Evaluation of the several methods for treating Graves' disease available today.", "content": "Evaluation of the several methods for treating Graves' disease available today.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996998"}
{"pmid": "20996999", "title": "Penicillin therapy alone in neurosyphilis; an analysis of clinical results.", "content": "Penicillin therapy alone in neurosyphilis; an analysis of clinical results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20996999"}
{"pmid": "20997000", "title": "An evaluation of sulfonamide mixtures and various adjuvants for control of sulfonamide crystalluria.", "content": "An evaluation of sulfonamide mixtures and various adjuvants for control of sulfonamide crystalluria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997000"}
{"pmid": "20997002", "title": "Hepatic insufficiency; pathophysiology and clinical aspects.", "content": "Hepatic insufficiency; pathophysiology and clinical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997002"}
{"pmid": "20997001", "title": "Immunization against influenza.", "content": "Immunization against influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997001"}
{"pmid": "20997003", "title": "Colorado tick fever.", "content": "Colorado tick fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997003"}
{"pmid": "20997004", "title": "COMMISSION ON ACUTE RESPIRATORY DISEASES. Association of acute pulmonary lesions with infections of the throat.", "content": "COMMISSION ON ACUTE RESPIRATORY DISEASES. Association of acute pulmonary lesions with infections of the throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997004"}
{"pmid": "20997005", "title": "Carbon tetrachloride poisoning; a report on one case with necropsy and one nonfatal case with clinical laboratory studies.", "content": "Carbon tetrachloride poisoning; a report on one case with necropsy and one nonfatal case with clinical laboratory studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997005"}
{"pmid": "20997006", "title": "Reiter's disease with prolonged auriculoventricular conduction.", "content": "Reiter's disease with prolonged auriculoventricular conduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997006"}
{"pmid": "20997008", "title": "Friedländer pneumonia treated with streptomycin; report of a case with prompt recovery.", "content": "Friedländer pneumonia treated with streptomycin; report of a case with prompt recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997008"}
{"pmid": "20997009", "title": "Hematoporphyrinuria; review of literature and report of a case of chronic type.", "content": "Hematoporphyrinuria; review of literature and report of a case of chronic type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997009"}
{"pmid": "20997007", "title": "Intoxication resulting from the administration of massive doses of vitamin D.", "content": "Intoxication resulting from the administration of massive doses of vitamin D.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997007"}
{"pmid": "20997010", "title": "Hodgkin's disease involving the pituitary gland with diabetes insipidus.", "content": "Hodgkin's disease involving the pituitary gland with diabetes insipidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997010"}
{"pmid": "20997013", "title": "Prognosis and treatment of leprosy.", "content": "Prognosis and treatment of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997013"}
{"pmid": "20997011", "title": "Magnesium sulfate in paroxysmal tachycardia.", "content": "Magnesium sulfate in paroxysmal tachycardia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997011"}
{"pmid": "20997012", "title": "FOLIC acid.", "content": "FOLIC acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997012"}
{"pmid": "20997015", "title": "Fevers of short duration.", "content": "Fevers of short duration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997015"}
{"pmid": "20997016", "title": "Causative factors and treatment in coronary thrombosis.", "content": "Causative factors and treatment in coronary thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997016"}
{"pmid": "20997017", "title": "Malaria; its various manifestations.", "content": "Malaria; its various manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997017"}
{"pmid": "20997014", "title": "The treatment of cholera and acute gastro-enteritis.", "content": "The treatment of cholera and acute gastro-enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997014"}
{"pmid": "20997018", "title": "Pediculosis.", "content": "Pediculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997018"}
{"pmid": "20997019", "title": "The origin of pulmonary tuberculosis and its prevention.", "content": "The origin of pulmonary tuberculosis and its prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997019"}
{"pmid": "20997021", "title": "Further light on the treatment of snake-bite.", "content": "Further light on the treatment of snake-bite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997021"}
{"pmid": "20997020", "title": "Giardiasis.", "content": "Giardiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997020"}
{"pmid": "20997022", "title": "Some clinical notes on the use of penicillin.", "content": "Some clinical notes on the use of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997022"}
{"pmid": "20997025", "title": "Chronic polyarthritis and trauma.", "content": "Chronic polyarthritis and trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997025"}
{"pmid": "20997023", "title": "Constipation; a key to its successful treatment.", "content": "Constipation; a key to its successful treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997023"}
{"pmid": "20997024", "title": "Anaemia.", "content": "Anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997024"}
{"pmid": "20997026", "title": "Pulmonary amoebiasis.", "content": "Pulmonary amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997026"}
{"pmid": "20997027", "title": "Infective hepatitis after anticholera inoculation.", "content": "Infective hepatitis after anticholera inoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997027"}
{"pmid": "20997028", "title": "Quinine idiosyncrasy.", "content": "Quinine idiosyncrasy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997028"}
{"pmid": "20997029", "title": "An interesting case of an accidental opium poisoning.", "content": "An interesting case of an accidental opium poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997029"}
{"pmid": "20997030", "title": "A rare case of ectopia cardica.", "content": "A rare case of ectopia cardica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997030"}
{"pmid": "20997031", "title": "A case of malaria with severe glossitis.", "content": "A case of malaria with severe glossitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997031"}
{"pmid": "20997032", "title": "An interesting case of foreign body in nose.", "content": "An interesting case of foreign body in nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997032"}
{"pmid": "20997033", "title": "A case of pyelitis.", "content": "A case of pyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997033"}
{"pmid": "20997034", "title": "A case of cerebral malaria.", "content": "A case of cerebral malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997034"}
{"pmid": "20997035", "title": "Discussion on the cases of adenomyosis and endometriosis.", "content": "Discussion on the cases of adenomyosis and endometriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997035"}
{"pmid": "20997037", "title": "Cataract.", "content": "Cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997037"}
{"pmid": "20997038", "title": "Sulpha drug in small-pox.", "content": "Sulpha drug in small-pox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997038"}
{"pmid": "20997039", "title": "Unfamiliar smallpox.", "content": "Unfamiliar smallpox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997039"}
{"pmid": "20997040", "title": "Cinchonine in the treatment of malaria.", "content": "Cinchonine in the treatment of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997040"}
{"pmid": "20997041", "title": "Hormone therapy; in the treatment of enlarged prostate.", "content": "Hormone therapy; in the treatment of enlarged prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997041"}
{"pmid": "20997036", "title": "Hysteria; its various clinical aspects and treatment with a case-note.", "content": "Hysteria; its various clinical aspects and treatment with a case-note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997036"}
{"pmid": "20997044", "title": "Penicillin in gonoarthritis.", "content": "Penicillin in gonoarthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997044"}
{"pmid": "20997043", "title": "A case of complicated duodenal ulcer.", "content": "A case of complicated duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997043"}
{"pmid": "20997042", "title": "Spontaneous recovery in a case of mental depression (schizophrenic); after ammonium chloride shock therapy.", "content": "Spontaneous recovery in a case of mental depression (schizophrenic); after ammonium chloride shock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997042"}
{"pmid": "20997045", "title": "A case of Naga sore.", "content": "A case of Naga sore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997045"}
{"pmid": "20997046", "title": "Coronary arteriosclerosis, coronary anastomoses and myocardial infarction; a clinicopathologic study based on an injection method.", "content": "Coronary arteriosclerosis, coronary anastomoses and myocardial infarction; a clinicopathologic study based on an injection method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997046"}
{"pmid": "20997047", "title": "Fulminating meningococcic septicemia associated with adrenal lesions.", "content": "Fulminating meningococcic septicemia associated with adrenal lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997047"}
{"pmid": "20997048", "title": "Rheumatic fever in naval enlisted personnel; effectiveness of intensive salicylate therapy in cases of acute infection.", "content": "Rheumatic fever in naval enlisted personnel; effectiveness of intensive salicylate therapy in cases of acute infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997048"}
{"pmid": "20997050", "title": "Congenital dilatation of the pulmonary arterial tree; relation to Ayerza's disease and primary pulmonary arteriosclerosis.", "content": "Congenital dilatation of the pulmonary arterial tree; relation to Ayerza's disease and primary pulmonary arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997050"}
{"pmid": "20997049", "title": "Changes in hemoglobin and total plasma protein after injection of mercurophylline.", "content": "Changes in hemoglobin and total plasma protein after injection of mercurophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997049"}
{"pmid": "20997051", "title": "Gastroenterology; a review of the literature from July 1944 to June 1945.", "content": "Gastroenterology; a review of the literature from July 1944 to June 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997051"}
{"pmid": "20997061", "title": "Migraine and the sympathetic nervous pathways.", "content": "Migraine and the sympathetic nervous pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997061"}
{"pmid": "20997062", "title": "Crash helmets.", "content": "Crash helmets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997062"}
{"pmid": "20997063", "title": "Penicillin in treatment of common external eye infections.", "content": "Penicillin in treatment of common external eye infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997063"}
{"pmid": "20997064", "title": "Hypersomnia associated with abnormal hunger; the Kleine-Levin syndrome.", "content": "Hypersomnia associated with abnormal hunger; the Kleine-Levin syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997064"}
{"pmid": "20997065", "title": "The xenopus pregnancy test.", "content": "The xenopus pregnancy test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997065"}
{"pmid": "20997066", "title": "Surgical treatment of deformities of the hallux by skin-grafting.", "content": "Surgical treatment of deformities of the hallux by skin-grafting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997066"}
{"pmid": "20997052", "title": "BLOOD transfusion.", "content": "BLOOD transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997052"}
{"pmid": "20997067", "title": "Rat scratch causing Weil's disease.", "content": "Rat scratch causing Weil's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997067"}
{"pmid": "20997068", "title": "A resistance type skin thermometer.", "content": "A resistance type skin thermometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997068"}
{"pmid": "20997069", "title": "Pleural shock or cerebral air embolism.", "content": "Pleural shock or cerebral air embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997069"}
{"pmid": "20997070", "title": "The incidence, incubation period, and symptomatology of homologous serum jaundice.", "content": "The incidence, incubation period, and symptomatology of homologous serum jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997070"}
{"pmid": "20997071", "title": "Post-operative activity and resumption of normal movement; their influence on embolism and thrombosis.", "content": "Post-operative activity and resumption of normal movement; their influence on embolism and thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997071"}
{"pmid": "20997072", "title": "Inability to work in a tropical climate.", "content": "Inability to work in a tropical climate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997072"}
{"pmid": "20997073", "title": "The faeces in sprue.", "content": "The faeces in sprue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997073"}
{"pmid": "20997074", "title": "Unilateral micromastia associated with abnormalities of musculature of chest wall on same side.", "content": "Unilateral micromastia associated with abnormalities of musculature of chest wall on same side.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997074"}
{"pmid": "20997075", "title": "A new penicillin inhaler.", "content": "A new penicillin inhaler.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997075"}
{"pmid": "20997076", "title": "The World Health Organization.", "content": "The World Health Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997076"}
{"pmid": "20997078", "title": "ARTIFICIAL leg for women.", "content": "ARTIFICIAL leg for women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997078"}
{"pmid": "20997077", "title": "Placing the tuberculous in industry.", "content": "Placing the tuberculous in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997077"}
{"pmid": "20997079", "title": "Pronunciation of medical words.", "content": "Pronunciation of medical words.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997079"}
{"pmid": "20997080", "title": "Postgraduate education and the National Health Service.", "content": "Postgraduate education and the National Health Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997080"}
{"pmid": "20997081", "title": "Some principles in the selection of medical students.", "content": "Some principles in the selection of medical students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997081"}
{"pmid": "20997082", "title": "Analysis of results of a test given at University College, London, for the selection of women medical students for the session 1945-6.", "content": "Analysis of results of a test given at University College, London, for the selection of women medical students for the session 1945-6.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997082"}
{"pmid": "20997083", "title": "The Medical Council of India.", "content": "The Medical Council of India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997083"}
{"pmid": "20997084", "title": "Post-operative occurrence of exophthalmic goitre.", "content": "Post-operative occurrence of exophthalmic goitre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997084"}
{"pmid": "20997086", "title": "MEDICAL schools.", "content": "MEDICAL schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997086"}
{"pmid": "20997085", "title": "Examinations; meditations on a painful theme.", "content": "Examinations; meditations on a painful theme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997085"}
{"pmid": "20997087", "title": "Substitution of an ankle for the knee joint of a prosthesis.", "content": "Substitution of an ankle for the knee joint of a prosthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997087"}
{"pmid": "20997088", "title": "Endocrine disorders of pregnancy.", "content": "Endocrine disorders of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997088"}
{"pmid": "20997089", "title": "Anesthesia.", "content": "Anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997089"}
{"pmid": "20997090", "title": "The diagnosis and management of rheumatoid spondylitis.", "content": "The diagnosis and management of rheumatoid spondylitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997090"}
{"pmid": "20997091", "title": "Some remarks on the nature and treatment of arterial hypertension.", "content": "Some remarks on the nature and treatment of arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997091"}
{"pmid": "20997092", "title": "Coronary death.", "content": "Coronary death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997092"}
{"pmid": "20997093", "title": "Coronary disease.", "content": "Coronary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997093"}
{"pmid": "20997094", "title": "Coordination of the activities of the industrial physician and the private practitioner.", "content": "Coordination of the activities of the industrial physician and the private practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997094"}
{"pmid": "20997096", "title": "Practical points in the dressing and nutrition of patients with burns.", "content": "Practical points in the dressing and nutrition of patients with burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997096"}
{"pmid": "20997095", "title": "Antibiotics.", "content": "Antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997095"}
{"pmid": "20997097", "title": "Endocrine regulation of menstruation and menstrual irregularities.", "content": "Endocrine regulation of menstruation and menstrual irregularities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997097"}
{"pmid": "20997098", "title": "Shock.", "content": "Shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997098"}
{"pmid": "20997099", "title": "Kidney and ureteral stones.", "content": "Kidney and ureteral stones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997099"}
{"pmid": "20997100", "title": "Anuria; differential diagnosis and treatment.", "content": "Anuria; differential diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997100"}
{"pmid": "20997101", "title": "Treatment of pain involving the face and associated regions.", "content": "Treatment of pain involving the face and associated regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997101"}
{"pmid": "20997104", "title": "The clinical correlation of in-vitro penicillin sensitivity tests.", "content": "The clinical correlation of in-vitro penicillin sensitivity tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997104"}
{"pmid": "20997108", "title": "The clinical evolution of vascular damage in diabetes mellitus.", "content": "The clinical evolution of vascular damage in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997108"}
{"pmid": "20997106", "title": "The etiologic agent of pemphigus vulgaris.", "content": "The etiologic agent of pemphigus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997106"}
{"pmid": "20997105", "title": "Repository injection of penicillin in water-in-oil emulsion.", "content": "Repository injection of penicillin in water-in-oil emulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997105"}
{"pmid": "20997107", "title": "Some pharmacological and clinical experiences with dimethylaminoethyl benzhydryl ether hydrochloride (benadryl).", "content": "Some pharmacological and clinical experiences with dimethylaminoethyl benzhydryl ether hydrochloride (benadryl).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997107"}
{"pmid": "20997109", "title": "Insulin resistance.", "content": "Insulin resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997109"}
{"pmid": "20997110", "title": "A study of histochemically demonstrable liver phosphatase in experimental obstructive jaundice and in human postmortem material.", "content": "A study of histochemically demonstrable liver phosphatase in experimental obstructive jaundice and in human postmortem material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997110"}
{"pmid": "20997111", "title": "The hernia congenita and an account of the controversy it provoked between William Hunter and Percivall Pott.", "content": "The hernia congenita and an account of the controversy it provoked between William Hunter and Percivall Pott.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997111"}
{"pmid": "20997123", "title": "Typhoid fever; specific treatment; serum therapy.", "content": "Typhoid fever; specific treatment; serum therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997123"}
{"pmid": "20997124", "title": "Pernicious anaemia.", "content": "Pernicious anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997124"}
{"pmid": "20997125", "title": "Treatment of malaria in India.", "content": "Treatment of malaria in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997125"}
{"pmid": "20997126", "title": "Corneal ulcer.", "content": "Corneal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997126"}
{"pmid": "20997127", "title": "Iron lungs save lives; cure for infantile paralysis.", "content": "Iron lungs save lives; cure for infantile paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997127"}
{"pmid": "20997128", "title": "NEW drug triumphs over malaria.", "content": "NEW drug triumphs over malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997128"}
{"pmid": "20997129", "title": "The effects of oestrogens and of mild chronic starvation on the white rat.", "content": "The effects of oestrogens and of mild chronic starvation on the white rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997129"}
{"pmid": "20997130", "title": "Effect of reducing agents on the viability of equine encephalomyelitis virus (Eastern type).", "content": "Effect of reducing agents on the viability of equine encephalomyelitis virus (Eastern type).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997130"}
{"pmid": "20997133", "title": "Actions of yatanoside; a principle of a Chinese drug ya tan tzu.", "content": "Actions of yatanoside; a principle of a Chinese drug ya tan tzu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997133"}
{"pmid": "20997132", "title": "The pharmacology of chia chu tao, a Chinese oleander.", "content": "The pharmacology of chia chu tao, a Chinese oleander.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997132"}
{"pmid": "20997134", "title": "A new specific for malaria; Caesalpinia sepiaria Roxb.", "content": "A new specific for malaria; Caesalpinia sepiaria Roxb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997134"}
{"pmid": "20997136", "title": "Inflammatory pseudotumor of the orbit.", "content": "Inflammatory pseudotumor of the orbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997136"}
{"pmid": "20997135", "title": "The non-ligation and inversion method for the appendical stump.", "content": "The non-ligation and inversion method for the appendical stump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997135"}
{"pmid": "20997137", "title": "On the occurrence of malignant malaria in villages near Peiping.", "content": "On the occurrence of malignant malaria in villages near Peiping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997137"}
{"pmid": "20997138", "title": "The anatomic distribution of the lesions in pulmonary tuberculosis.", "content": "The anatomic distribution of the lesions in pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997138"}
{"pmid": "20997139", "title": "A simple method of destroying bedbugs.", "content": "A simple method of destroying bedbugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997139"}
{"pmid": "20997140", "title": "Studies on the biology and control of bedbugs.", "content": "Studies on the biology and control of bedbugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997140"}
{"pmid": "20997142", "title": "Neuroblastoma of the adrenal with multiple metastases.", "content": "Neuroblastoma of the adrenal with multiple metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997142"}
{"pmid": "20997141", "title": "Preparation of DDT emulsions using locally available solvents, and their insecticidal action against body lice.", "content": "Preparation of DDT emulsions using locally available solvents, and their insecticidal action against body lice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997141"}
{"pmid": "20997143", "title": "Incipient pannus as a sign of the primary corneal infection of trachoma and as an important criterion for the early diagnosis of the disease.", "content": "Incipient pannus as a sign of the primary corneal infection of trachoma and as an important criterion for the early diagnosis of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997143"}
{"pmid": "20997145", "title": "The treatment of congestive cardiac failure with special reference to the prolonged use of mercurial diuretics.", "content": "The treatment of congestive cardiac failure with special reference to the prolonged use of mercurial diuretics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997145"}
{"pmid": "20997144", "title": "Conjunctival myiasis; caused by Lucilia sericata, green bottle fly.", "content": "Conjunctival myiasis; caused by Lucilia sericata, green bottle fly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997144"}
{"pmid": "20997131", "title": "Difference in responses of Leishmania canis and Leishmania donovani toward ureastibamine.", "content": "Difference in responses of Leishmania canis and Leishmania donovani toward ureastibamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997131"}
{"pmid": "20997146", "title": "The diagnosis and treatment of congenital cardiovascular anomalies.", "content": "The diagnosis and treatment of congenital cardiovascular anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997146"}
{"pmid": "20997147", "title": "Treatment of acute rheumatic carditis.", "content": "Treatment of acute rheumatic carditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997147"}
{"pmid": "20997148", "title": "Convalescent care in rheumatic fever.", "content": "Convalescent care in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997148"}
{"pmid": "20997149", "title": "The treatment of subacute bacterial endocarditis.", "content": "The treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997149"}
{"pmid": "20997153", "title": "Comments on chronic coronary disease.", "content": "Comments on chronic coronary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997153"}
{"pmid": "20997152", "title": "The treatment of acute myocardial infarction.", "content": "The treatment of acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997152"}
{"pmid": "20997151", "title": "The diagnosis and treatment of acute pericarditis.", "content": "The diagnosis and treatment of acute pericarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997151"}
{"pmid": "20997150", "title": "The medical treatment of hypertension.", "content": "The medical treatment of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997150"}
{"pmid": "20997155", "title": "Some thoughts on the diagnosis and treatment of pulmonary heart disease (cor pulmonale).", "content": "Some thoughts on the diagnosis and treatment of pulmonary heart disease (cor pulmonale).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997155"}
{"pmid": "20997154", "title": "The diagnosis and treatment of cardiovascular syphilis.", "content": "The diagnosis and treatment of cardiovascular syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997154"}
{"pmid": "20997156", "title": "Primary sarcoma of the pulmonary artery.", "content": "Primary sarcoma of the pulmonary artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997156"}
{"pmid": "20997159", "title": "Review of surgery of the heart.", "content": "Review of surgery of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997159"}
{"pmid": "20997158", "title": "The meaning of the electrocardiogram and its value to the general practitioner.", "content": "The meaning of the electrocardiogram and its value to the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997158"}
{"pmid": "20997161", "title": "Recent trends in the diagnosis and treatment of peripheral vascular disease.", "content": "Recent trends in the diagnosis and treatment of peripheral vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997161"}
{"pmid": "20997160", "title": "Psychosomatic aspects of cardiovascular disease.", "content": "Psychosomatic aspects of cardiovascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997160"}
{"pmid": "20997157", "title": "Clinical disorders of the heart beat.", "content": "Clinical disorders of the heart beat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997157"}
{"pmid": "20997162", "title": "The treatment of poliomyelitis under orthodox, Kenny, and prostigmine methods.", "content": "The treatment of poliomyelitis under orthodox, Kenny, and prostigmine methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997162"}
{"pmid": "20997163", "title": "Evaluation of spinal fluid examination of patients with poliomyelitis.", "content": "Evaluation of spinal fluid examination of patients with poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997163"}
{"pmid": "20997164", "title": "Interpretation of semen studies.", "content": "Interpretation of semen studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997164"}
{"pmid": "20997167", "title": "Dissecting aneurysm of right colic artery.", "content": "Dissecting aneurysm of right colic artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997167"}
{"pmid": "20997165", "title": "Urologic observations in the European Theatre of Operations.", "content": "Urologic observations in the European Theatre of Operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997165"}
{"pmid": "20997169", "title": "Lobectomy and pneumonectomy in pulmonary tuberculosis.", "content": "Lobectomy and pneumonectomy in pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997169"}
{"pmid": "20997166", "title": "Fetal blackout.", "content": "Fetal blackout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997166"}
{"pmid": "20997183", "title": "The gallbladder and duct problem.", "content": "The gallbladder and duct problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997183"}
{"pmid": "20997168", "title": "Pulmonary coccidioidomycosis.", "content": "Pulmonary coccidioidomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997168"}
{"pmid": "20997184", "title": "Corrective surgery of the external nasal pyramid and the nasal septum for restoration of normal physiology.", "content": "Corrective surgery of the external nasal pyramid and the nasal septum for restoration of normal physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997184"}
{"pmid": "20997171", "title": "Pulmonary actinomycosis (report of the first case observed in the Isthmus of Panama).", "content": "Pulmonary actinomycosis (report of the first case observed in the Isthmus of Panama).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997171"}
{"pmid": "20997185", "title": "Carcinoma of the male breast.", "content": "Carcinoma of the male breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997185"}
{"pmid": "20997173", "title": "Obstructing tuberculosis of the main bronchi; a syndrome.", "content": "Obstructing tuberculosis of the main bronchi; a syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997173"}
{"pmid": "20997170", "title": "Spontaneous hemothorax.", "content": "Spontaneous hemothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997170"}
{"pmid": "20997177", "title": "Non-coagulating intrapleural hemorrhage following damage to intercostal vessels.", "content": "Non-coagulating intrapleural hemorrhage following damage to intercostal vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997177"}
{"pmid": "20997186", "title": "Suicide and homicide in relation to sexual difficulties.", "content": "Suicide and homicide in relation to sexual difficulties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997186"}
{"pmid": "20997174", "title": "Pulmonary cavitation, difficulty in differential diagnosis by x-ray.", "content": "Pulmonary cavitation, difficulty in differential diagnosis by x-ray.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997174"}
{"pmid": "20997187", "title": "Hypertension; high arterial pressure (arterio-sclerosis and cardio-renal conditions).", "content": "Hypertension; high arterial pressure (arterio-sclerosis and cardio-renal conditions).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997187"}
{"pmid": "20997178", "title": "Role of the tuberculosis sanatorium in the community.", "content": "Role of the tuberculosis sanatorium in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997178"}
{"pmid": "20997189", "title": "Rehabilitation of the tuberculous in industry.", "content": "Rehabilitation of the tuberculous in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997189"}
{"pmid": "20997188", "title": "The nature and treatment of cholecystitis.", "content": "The nature and treatment of cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997188"}
{"pmid": "20997172", "title": "Vitamin D; its bactericidal action.", "content": "Vitamin D; its bactericidal action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997172"}
{"pmid": "20997190", "title": "Streptomycin in the treatment of subacute bacterial endocarditis.", "content": "Streptomycin in the treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997190"}
{"pmid": "20997191", "title": "Nitrogen mustard therapy; use of methyl-bis (beta-chloroethyl) amine hydrochloride and tris (beta-chloroethyl) amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders.", "content": "Nitrogen mustard therapy; use of methyl-bis (beta-chloroethyl) amine hydrochloride and tris (beta-chloroethyl) amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997191"}
{"pmid": "20997176", "title": "Concurrence of superior pulmonary sulcus tumor and pulmonary tuberculosis.", "content": "Concurrence of superior pulmonary sulcus tumor and pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997176"}
{"pmid": "20997192", "title": "Recurrent hiatus hernia.", "content": "Recurrent hiatus hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997192"}
{"pmid": "20997175", "title": "Results of thoracoplasty (933 cases, 1,868 operations).", "content": "Results of thoracoplasty (933 cases, 1,868 operations).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997175"}
{"pmid": "20997179", "title": "GENERAL code relating to the control of tuberculosis by modern means.", "content": "GENERAL code relating to the control of tuberculosis by modern means.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997179"}
{"pmid": "20997193", "title": "Treatment of typhoid fever with type specific bacteriophage.", "content": "Treatment of typhoid fever with type specific bacteriophage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997193"}
{"pmid": "20997194", "title": "The use of residual hearing.", "content": "The use of residual hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997194"}
{"pmid": "20997195", "title": "Serious air embolism during blood donation.", "content": "Serious air embolism during blood donation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997195"}
{"pmid": "20997196", "title": "Oxidized cellulose gauze packing for nasal bleeding.", "content": "Oxidized cellulose gauze packing for nasal bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997196"}
{"pmid": "20997197", "title": "Habitual hyperthermia; premenstrual fever.", "content": "Habitual hyperthermia; premenstrual fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997197"}
{"pmid": "20997199", "title": "The male climacteric.", "content": "The male climacteric.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997199"}
{"pmid": "20997198", "title": "Uses and abuses of the male sex hormone.", "content": "Uses and abuses of the male sex hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997198"}
{"pmid": "20997200", "title": "Streptomycin treatment in tularemia.", "content": "Streptomycin treatment in tularemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997200"}
{"pmid": "20997201", "title": "Streptomycin; its clinical uses and limitations.", "content": "Streptomycin; its clinical uses and limitations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997201"}
{"pmid": "20997202", "title": "Present status of the study of child health services.", "content": "Present status of the study of child health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997202"}
{"pmid": "20997203", "title": "Subacute bacterial endocarditis due to gram negative organisms.", "content": "Subacute bacterial endocarditis due to gram negative organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997203"}
{"pmid": "20997204", "title": "Pressure dressings for the prevention and treatment of thromboembolism.", "content": "Pressure dressings for the prevention and treatment of thromboembolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997204"}
{"pmid": "20997205", "title": "Benadryl, a contributing cause of an accident.", "content": "Benadryl, a contributing cause of an accident.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997205"}
{"pmid": "20997206", "title": "Penicillin by iontophoresis.", "content": "Penicillin by iontophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997206"}
{"pmid": "20997207", "title": "Laboratory tests in general practice.", "content": "Laboratory tests in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997207"}
{"pmid": "20997208", "title": "Results of rapid treatment of early syphilis.", "content": "Results of rapid treatment of early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997208"}
{"pmid": "20997209", "title": "Nitrogen mustard therapy; studies on the effect of methyl-bis (beta-chloroethyl) amine hydrochloride on neoplastic diseases and allied disorders of the hemopoietic system.", "content": "Nitrogen mustard therapy; studies on the effect of methyl-bis (beta-chloroethyl) amine hydrochloride on neoplastic diseases and allied disorders of the hemopoietic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997209"}
{"pmid": "20997210", "title": "Penicillin spray by bulb atomizer in respiratory infections.", "content": "Penicillin spray by bulb atomizer in respiratory infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997210"}
{"pmid": "20997211", "title": "Enuresis, a psychologic problem of childhood.", "content": "Enuresis, a psychologic problem of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997211"}
{"pmid": "20997212", "title": "Neurosyphilitic patients treated with penicillin; probable Herxheimer reactions.", "content": "Neurosyphilitic patients treated with penicillin; probable Herxheimer reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997212"}
{"pmid": "20997213", "title": "Modern concepts of intestinal function.", "content": "Modern concepts of intestinal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997213"}
{"pmid": "20997214", "title": "Acute conditions in abdomen as they concern the general practitioner.", "content": "Acute conditions in abdomen as they concern the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997214"}
{"pmid": "20997216", "title": "Peripheral neuritis as a complication of penicillin therapy.", "content": "Peripheral neuritis as a complication of penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997216"}
{"pmid": "20997215", "title": "Activity of a new antimalarial agent, pentaquine (SN 13,276).", "content": "Activity of a new antimalarial agent, pentaquine (SN 13,276).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997215"}
{"pmid": "20997217", "title": "Medical care in Maryland.", "content": "Medical care in Maryland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997217"}
{"pmid": "20997218", "title": "The use of gelatin sponge in neurosurgery.", "content": "The use of gelatin sponge in neurosurgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997218"}
{"pmid": "20997219", "title": "Poisoning due to oil of chenopodium.", "content": "Poisoning due to oil of chenopodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997219"}
{"pmid": "20997220", "title": "Traumatic intracranial hemorrhage following closed head injury.", "content": "Traumatic intracranial hemorrhage following closed head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997220"}
{"pmid": "20997221", "title": "Poliomyelitis; clinical and epidemiological considerations.", "content": "Poliomyelitis; clinical and epidemiological considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997221"}
{"pmid": "20997222", "title": "Treatment of poliomyelitis.", "content": "Treatment of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997222"}
{"pmid": "20997223", "title": "The clinical importance of congenital anomalies of the urinary tract.", "content": "The clinical importance of congenital anomalies of the urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997223"}
{"pmid": "20997224", "title": "Headaches associated with injuries of the cervical spine.", "content": "Headaches associated with injuries of the cervical spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997224"}
{"pmid": "20997225", "title": "Pediatric problems in general practice.", "content": "Pediatric problems in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997225"}
{"pmid": "20997226", "title": "Congenital venereal diseases.", "content": "Congenital venereal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997226"}
{"pmid": "20997227", "title": "Psychosomatic gynecology.", "content": "Psychosomatic gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997227"}
{"pmid": "20997228", "title": "Psychosomatic aspects of problem cases in medicine and surgery.", "content": "Psychosomatic aspects of problem cases in medicine and surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997228"}
{"pmid": "20997229", "title": "Man versus the amoeba.", "content": "Man versus the amoeba.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997229"}
{"pmid": "20997237", "title": "An experiment in free chlorination of public water supplies.", "content": "An experiment in free chlorination of public water supplies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997237"}
{"pmid": "20997236", "title": "New anti-histamine drugs in allergic diseases.", "content": "New anti-histamine drugs in allergic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997236"}
{"pmid": "20997238", "title": "Imported tropical disease; a community problem.", "content": "Imported tropical disease; a community problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997238"}
{"pmid": "20997239", "title": "Medicine and industrial research.", "content": "Medicine and industrial research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997239"}
{"pmid": "20997240", "title": "The diagnosis and treatment of pernicious anemia.", "content": "The diagnosis and treatment of pernicious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997240"}
{"pmid": "20997241", "title": "A survey of the pneumonias.", "content": "A survey of the pneumonias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997241"}
{"pmid": "20997242", "title": "Myasthenia gravis.", "content": "Myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997242"}
{"pmid": "20997243", "title": "Sympathetic nerve interruption in the treatment of organic obstructive vascular disease.", "content": "Sympathetic nerve interruption in the treatment of organic obstructive vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997243"}
{"pmid": "20997244", "title": "Pyelocystostomy in an infant.", "content": "Pyelocystostomy in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997244"}
{"pmid": "20997245", "title": "Some technical considerations in thyroidectomy.", "content": "Some technical considerations in thyroidectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997245"}
{"pmid": "20997246", "title": "Relief of sulfadiazine anuria by spinal anesthesia.", "content": "Relief of sulfadiazine anuria by spinal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997246"}
{"pmid": "20997247", "title": "Demerol analgesia in labor combined with spinal anesthesia for vaginal delivery.", "content": "Demerol analgesia in labor combined with spinal anesthesia for vaginal delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997247"}
{"pmid": "20997248", "title": "Para-amino-benzoic acid in the prevention of sunburn.", "content": "Para-amino-benzoic acid in the prevention of sunburn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997248"}
{"pmid": "20997249", "title": "Epidemic thrombophlebitis in the East Africa command.", "content": "Epidemic thrombophlebitis in the East Africa command.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997249"}
{"pmid": "20997250", "title": "Nausea and vomiting of pregnancy; a study in psychosomatic and social medicine.", "content": "Nausea and vomiting of pregnancy; a study in psychosomatic and social medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997250"}
{"pmid": "20997251", "title": "Calf plasma or serum for transfusion.", "content": "Calf plasma or serum for transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997251"}
{"pmid": "20997252", "title": "Typhoid carriers; treated with penicillin and sulphathiazole.", "content": "Typhoid carriers; treated with penicillin and sulphathiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997252"}
{"pmid": "20997253", "title": "Pyridoxine (vitamin B6) in epilepsy; a clinical trial.", "content": "Pyridoxine (vitamin B6) in epilepsy; a clinical trial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997253"}
{"pmid": "20997254", "title": "Peritoneal nodules of unknown aetiology.", "content": "Peritoneal nodules of unknown aetiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997254"}
{"pmid": "20997255", "title": "Simple apparatus for micro-sublimation.", "content": "Simple apparatus for micro-sublimation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997255"}
{"pmid": "20997256", "title": "Fractional test-meals on students awaiting examination results.", "content": "Fractional test-meals on students awaiting examination results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997256"}
{"pmid": "20997257", "title": "The World Health Organisation and its interim commission.", "content": "The World Health Organisation and its interim commission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997257"}
{"pmid": "20997258", "title": "Painful feet in prisoners-of-war in the Far East.", "content": "Painful feet in prisoners-of-war in the Far East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997258"}
{"pmid": "20997259", "title": "Folic acid in the treatment of megaloblastic anaemia.", "content": "Folic acid in the treatment of megaloblastic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997259"}
{"pmid": "20997260", "title": "Confusion of amoeboma with carcinoma.", "content": "Confusion of amoeboma with carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997260"}
{"pmid": "20997261", "title": "Gout in leukaemia.", "content": "Gout in leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997261"}
{"pmid": "20997262", "title": "Tuberculous abscess following intramuscular penicillin.", "content": "Tuberculous abscess following intramuscular penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997262"}
{"pmid": "20997263", "title": "Light-weight oxygen mask of plastic material.", "content": "Light-weight oxygen mask of plastic material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997263"}
{"pmid": "20997264", "title": "Picrotoxin in barbiturate overdosage.", "content": "Picrotoxin in barbiturate overdosage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997264"}
{"pmid": "20997265", "title": "Length of stay in hospital.", "content": "Length of stay in hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997265"}
{"pmid": "20997266", "title": "Nutritional optic neuropathy.", "content": "Nutritional optic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997266"}
{"pmid": "20997267", "title": "Recent developments in neurology and psychiatry.", "content": "Recent developments in neurology and psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997267"}
{"pmid": "20997268", "title": "Penicillin therapy in the practice of internal medicine and pediatrics.", "content": "Penicillin therapy in the practice of internal medicine and pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997268"}
{"pmid": "20997269", "title": "Papillary cystadenocarcinoma of the ovary.", "content": "Papillary cystadenocarcinoma of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997269"}
{"pmid": "20997270", "title": "The expert medical witness.", "content": "The expert medical witness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997270"}
{"pmid": "20997271", "title": "Physicians favor Taft Health Bill.", "content": "Physicians favor Taft Health Bill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997271"}
{"pmid": "20997272", "title": "The Duluth Clinic.", "content": "The Duluth Clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997272"}
{"pmid": "20997273", "title": "Doctors face complex advisory role as adoptions boom.", "content": "Doctors face complex advisory role as adoptions boom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997273"}
{"pmid": "20997274", "title": "Industrial medicine comes of age.", "content": "Industrial medicine comes of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997274"}
{"pmid": "20997275", "title": "The salary system: handcuffs for the anesthesiologist.", "content": "The salary system: handcuffs for the anesthesiologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997275"}
{"pmid": "20997276", "title": "The child welfare services and the general practitioner.", "content": "The child welfare services and the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997276"}
{"pmid": "20997277", "title": "The modern treatment of syphilis.", "content": "The modern treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997277"}
{"pmid": "20997278", "title": "The treatment of myasthenia gravis.", "content": "The treatment of myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997278"}
{"pmid": "20997279", "title": "National aspect of deafness.", "content": "National aspect of deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997279"}
{"pmid": "20997280", "title": "The modern treatment of epilepsy in general practice.", "content": "The modern treatment of epilepsy in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997280"}
{"pmid": "20997281", "title": "Injuries of the knee-joint.", "content": "Injuries of the knee-joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997281"}
{"pmid": "20997282", "title": "Gold therapy in dermatology.", "content": "Gold therapy in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997282"}
{"pmid": "20997283", "title": "The history of deafness and its treatment.", "content": "The history of deafness and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997283"}
{"pmid": "20997284", "title": "The school medical service.", "content": "The school medical service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997284"}
{"pmid": "20997285", "title": "The modern treatment of acne.", "content": "The modern treatment of acne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997285"}
{"pmid": "20997286", "title": "Some common fractures of the arm.", "content": "Some common fractures of the arm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997286"}
{"pmid": "20997287", "title": "Pathology of deafness.", "content": "Pathology of deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997287"}
{"pmid": "20997288", "title": "Strangulation of the appendix through a window in the mesentery causing intestinal obstruction.", "content": "Strangulation of the appendix through a window in the mesentery causing intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997288"}
{"pmid": "20997289", "title": "Treatment and prognosis in urinary lithiasis.", "content": "Treatment and prognosis in urinary lithiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997289"}
{"pmid": "20997290", "title": "The diagnosis of diphtheria and the immunisation of children of school age.", "content": "The diagnosis of diphtheria and the immunisation of children of school age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997290"}
{"pmid": "20997291", "title": "Diagnosis of deafness.", "content": "Diagnosis of deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997291"}
{"pmid": "20997292", "title": "Aseptic surgical photography; a simple method for recording operative procedure.", "content": "Aseptic surgical photography; a simple method for recording operative procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997292"}
{"pmid": "20997293", "title": "Sexual inversion and the English law.", "content": "Sexual inversion and the English law.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997293"}
{"pmid": "20997294", "title": "The child guidance service.", "content": "The child guidance service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997294"}
{"pmid": "20997296", "title": "The anxiety syndrome.", "content": "The anxiety syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997296"}
{"pmid": "20997295", "title": "The modern treatment of metrorrhagia.", "content": "The modern treatment of metrorrhagia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997295"}
{"pmid": "20997297", "title": "The staff of life.", "content": "The staff of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997297"}
{"pmid": "20997298", "title": "Prevention of deafness.", "content": "Prevention of deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997298"}
{"pmid": "20997299", "title": "CAR for the disabled.", "content": "CAR for the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997299"}
{"pmid": "20997300", "title": "The modern treatment of obsessional neurosis.", "content": "The modern treatment of obsessional neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997300"}
{"pmid": "20997301", "title": "Post-operative complications.", "content": "Post-operative complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997301"}
{"pmid": "20997302", "title": "The infant who fails to thrive.", "content": "The infant who fails to thrive.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997302"}
{"pmid": "20997303", "title": "The place of the brain in hearing.", "content": "The place of the brain in hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997303"}
{"pmid": "20997304", "title": "Public orthopaedic services.", "content": "Public orthopaedic services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997304"}
{"pmid": "20997305", "title": "The treatment of ulcerative colitis.", "content": "The treatment of ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997305"}
{"pmid": "20997306", "title": "Inhalations of penicillin.", "content": "Inhalations of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997306"}
{"pmid": "20997307", "title": "Treatment of deafness.", "content": "Treatment of deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997307"}
{"pmid": "20997308", "title": "The use of a new vasoconstrictor-penicillin combination in the treatment of upper respiratory infections.", "content": "The use of a new vasoconstrictor-penicillin combination in the treatment of upper respiratory infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997308"}
{"pmid": "20997309", "title": "Treatment of thrombophlebitis.", "content": "Treatment of thrombophlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997309"}
{"pmid": "20997310", "title": "Medical therapy in sudden arterial occlusion.", "content": "Medical therapy in sudden arterial occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997310"}
{"pmid": "20997311", "title": "Review of five years' cesarean sections at Nassau Hospital.", "content": "Review of five years' cesarean sections at Nassau Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997311"}
{"pmid": "20997312", "title": "Report of a case of Aspergillus fumigatus infection of the tracheobronchial tree.", "content": "Report of a case of Aspergillus fumigatus infection of the tracheobronchial tree.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997312"}
{"pmid": "20997313", "title": "Lymphosarcoma of the stomach.", "content": "Lymphosarcoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997313"}
{"pmid": "20997314", "title": "Search and research.", "content": "Search and research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997314"}
{"pmid": "20997315", "title": "The collection center for microbic types at the School of Medicine of Lausanne.", "content": "The collection center for microbic types at the School of Medicine of Lausanne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997315"}
{"pmid": "20997316", "title": "The laboratory in general practice.", "content": "The laboratory in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997316"}
{"pmid": "20997317", "title": "Devices in management and treatment of essential hypertension.", "content": "Devices in management and treatment of essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997317"}
{"pmid": "20997318", "title": "Report of peripheral nerve crushing for pain in vascular disease.", "content": "Report of peripheral nerve crushing for pain in vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997318"}
{"pmid": "20997319", "title": "Pathological relationship of inspissated blood to fibrous tissue formation.", "content": "Pathological relationship of inspissated blood to fibrous tissue formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997319"}
{"pmid": "20997321", "title": "Clinical and therapeutic aspects of the conflagration injuries to the respiratory tract sustained by victims of the Cocoanut Grove disaster.", "content": "Clinical and therapeutic aspects of the conflagration injuries to the respiratory tract sustained by victims of the Cocoanut Grove disaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997321"}
{"pmid": "20997322", "title": "The coronary circulation.", "content": "The coronary circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997322"}
{"pmid": "20997323", "title": "Coronary heart disease; the occupational disease of doctors.", "content": "Coronary heart disease; the occupational disease of doctors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997323"}
{"pmid": "20997324", "title": "Coronary heart disease; prognosis and life adaptation.", "content": "Coronary heart disease; prognosis and life adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997324"}
{"pmid": "20997325", "title": "The treatment of the coronary emergency.", "content": "The treatment of the coronary emergency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997325"}
{"pmid": "20997326", "title": "The outlook for postwar medicine as seen by a radiologist.", "content": "The outlook for postwar medicine as seen by a radiologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997326"}
{"pmid": "20997327", "title": "Surgical treatment of bronchiectasis.", "content": "Surgical treatment of bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997327"}
{"pmid": "20997328", "title": "The value of the X-ray examination in the diagnosis of ruptured intervertebral disc.", "content": "The value of the X-ray examination in the diagnosis of ruptured intervertebral disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997328"}
{"pmid": "20997329", "title": "Diagnostic case report [polyarteriitis nodosa].", "content": "Diagnostic case report [polyarteriitis nodosa].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997329"}
{"pmid": "20997330", "title": "Intra-arterial penicillin therapy for infections of the extremities.", "content": "Intra-arterial penicillin therapy for infections of the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997330"}
{"pmid": "20997331", "title": "A new type of walking iron; historical review of the ambulatory treatment of leg fractures.", "content": "A new type of walking iron; historical review of the ambulatory treatment of leg fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997331"}
{"pmid": "20997332", "title": "Acute non-malignant perforations of the colon.", "content": "Acute non-malignant perforations of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997332"}
{"pmid": "20997333", "title": "Problems in tropical medicine and parasitology among returnees from World War II.", "content": "Problems in tropical medicine and parasitology among returnees from World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997333"}
{"pmid": "20997334", "title": "Evaluation of heart before surgery.", "content": "Evaluation of heart before surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997334"}
{"pmid": "20997335", "title": "Pulmonary tuberculosis in Harvard medical students.", "content": "Pulmonary tuberculosis in Harvard medical students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997335"}
{"pmid": "20997336", "title": "Dyspepsia, ulcer and gastric cancer.", "content": "Dyspepsia, ulcer and gastric cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997336"}
{"pmid": "20997337", "title": "Vaginal ureteral orifices.", "content": "Vaginal ureteral orifices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997337"}
{"pmid": "20997338", "title": "The use of streptomycin in colon-bacillus peritonitis.", "content": "The use of streptomycin in colon-bacillus peritonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997338"}
{"pmid": "20997339", "title": "Papillary carcinoma of ureter, right.", "content": "Papillary carcinoma of ureter, right.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997339"}
{"pmid": "20997341", "title": "An unusual foreign body.", "content": "An unusual foreign body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997341"}
{"pmid": "20997340", "title": "Dermoid cyst of ovary, with torsion and infarction.", "content": "Dermoid cyst of ovary, with torsion and infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997340"}
{"pmid": "20997342", "title": "Twelve years' experience in roentgenotherapy for chronic arthritis.", "content": "Twelve years' experience in roentgenotherapy for chronic arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997342"}
{"pmid": "20997343", "title": "The delayed primary attack of vivax malaria.", "content": "The delayed primary attack of vivax malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997343"}
{"pmid": "20997344", "title": "Quartan malaria occurring subsequent to a blood transfusion.", "content": "Quartan malaria occurring subsequent to a blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997344"}
{"pmid": "20997345", "title": "Pelvic inflammatory disease.", "content": "Pelvic inflammatory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997345"}
{"pmid": "20997346", "title": "Occupational dermatoses.", "content": "Occupational dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997346"}
{"pmid": "20997347", "title": "Periarteritis nodosa.", "content": "Periarteritis nodosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997347"}
{"pmid": "20997348", "title": "Perinephric abscess secondary to renal-cell carcinoma.", "content": "Perinephric abscess secondary to renal-cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997348"}
{"pmid": "20997349", "title": "Mixed tumors of the parotid gland.", "content": "Mixed tumors of the parotid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997349"}
{"pmid": "20997350", "title": "Some common errors in fracture treatment.", "content": "Some common errors in fracture treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997350"}
{"pmid": "20997351", "title": "A symposium on sodium and water balance; distribution of potassium and sodium in body.", "content": "A symposium on sodium and water balance; distribution of potassium and sodium in body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997351"}
{"pmid": "20997352", "title": "Bound water.", "content": "Bound water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997352"}
{"pmid": "20997353", "title": "Sodium and potassium in relation to the action of diuretics.", "content": "Sodium and potassium in relation to the action of diuretics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997353"}
{"pmid": "20997354", "title": "The role of the adrenal gland in sodium and water exchange.", "content": "The role of the adrenal gland in sodium and water exchange.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997354"}
{"pmid": "20997355", "title": "The antidiuretic hormone.", "content": "The antidiuretic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997355"}
{"pmid": "20997356", "title": "The diuretic hormone.", "content": "The diuretic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997356"}
{"pmid": "20997357", "title": "Turnover of water and salt.", "content": "Turnover of water and salt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997357"}
{"pmid": "20997359", "title": "Recent progress in dermatology.", "content": "Recent progress in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997359"}
{"pmid": "20997358", "title": "Water and sodium balance in congestive heart failure.", "content": "Water and sodium balance in congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997358"}
{"pmid": "20997360", "title": "Five ten year possibilities.", "content": "Five ten year possibilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997360"}
{"pmid": "20997361", "title": "Evaluation of cardiac patients for surgery.", "content": "Evaluation of cardiac patients for surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997361"}
{"pmid": "20997362", "title": "Pentothal-time quotient: an instructional aid.", "content": "Pentothal-time quotient: an instructional aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997362"}
{"pmid": "20997363", "title": "Factors involved in the choice of premedication for anesthesia.", "content": "Factors involved in the choice of premedication for anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997363"}
{"pmid": "20997364", "title": "An analysis of maternal deaths for 12 years in Monroe County including Rochester.", "content": "An analysis of maternal deaths for 12 years in Monroe County including Rochester.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997364"}
{"pmid": "20997365", "title": "Unexpected sudden death after virus pneumonia in a patient with unusual constitutional abnormalities.", "content": "Unexpected sudden death after virus pneumonia in a patient with unusual constitutional abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997365"}
{"pmid": "20997366", "title": "Streptomycin in typhoid fever; review of current literature and usage.", "content": "Streptomycin in typhoid fever; review of current literature and usage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997366"}
{"pmid": "20997367", "title": "Rupture of the jejunum without evident external trauma.", "content": "Rupture of the jejunum without evident external trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997367"}
{"pmid": "20997368", "title": "The route of percutaneously applied antigen transported through the body by electrophoresis.", "content": "The route of percutaneously applied antigen transported through the body by electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997368"}
{"pmid": "20997369", "title": "Penicillin ointment in the treatment of diseases of the skin.", "content": "Penicillin ointment in the treatment of diseases of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997369"}
{"pmid": "20997370", "title": "Resistant dermatophytosis and its treatment.", "content": "Resistant dermatophytosis and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997370"}
{"pmid": "20997371", "title": "Syphilis in Army separatees.", "content": "Syphilis in Army separatees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997371"}
{"pmid": "20997372", "title": "Amebiasis in diagnostic dilemmas.", "content": "Amebiasis in diagnostic dilemmas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997372"}
{"pmid": "20997373", "title": "Lymphoblastoma of the terminal ileum.", "content": "Lymphoblastoma of the terminal ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997373"}
{"pmid": "20997385", "title": "The soul of medicine.", "content": "The soul of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997385"}
{"pmid": "20997386", "title": "Complications of Colles' fractures.", "content": "Complications of Colles' fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997386"}
{"pmid": "20997388", "title": "The present status of penicillin in the treatment of syphilis.", "content": "The present status of penicillin in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997388"}
{"pmid": "20997387", "title": "The role of guanidine in the therapy of myasthenia gravis.", "content": "The role of guanidine in the therapy of myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997387"}
{"pmid": "20997389", "title": "Meningitis due to Hemophilus influenzae; report of two cases successfully treated with penicillin and sulfadiazine.", "content": "Meningitis due to Hemophilus influenzae; report of two cases successfully treated with penicillin and sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997389"}
{"pmid": "20997390", "title": "Treatment of subacute bacterial endodarditis with penicillin.", "content": "Treatment of subacute bacterial endodarditis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997390"}
{"pmid": "20997391", "title": "Penicillin in hordeolosis.", "content": "Penicillin in hordeolosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997391"}
{"pmid": "20997392", "title": "Salmonella fever; report of five cases, one complicated by cholecystitis, perforation and peritonitis with autopsy findings.", "content": "Salmonella fever; report of five cases, one complicated by cholecystitis, perforation and peritonitis with autopsy findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997392"}
{"pmid": "20997393", "title": "Thrombus in femoral vein from great saphenous vein.", "content": "Thrombus in femoral vein from great saphenous vein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997393"}
{"pmid": "20997394", "title": "Rabies in Washington state.", "content": "Rabies in Washington state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997394"}
{"pmid": "20997395", "title": "Practical evaluation of the newer hepatic function tests.", "content": "Practical evaluation of the newer hepatic function tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997395"}
{"pmid": "20997396", "title": "Treatment of acute bone infections with penicillin and sulfonamides.", "content": "Treatment of acute bone infections with penicillin and sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997396"}
{"pmid": "20997397", "title": "Standardization of hemoglobin determinations in industry.", "content": "Standardization of hemoglobin determinations in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997397"}
{"pmid": "20997398", "title": "Post wartime nutrition.", "content": "Post wartime nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997398"}
{"pmid": "20997399", "title": "Laboratory examinations in relation to penicillin and streptomycin therapy.", "content": "Laboratory examinations in relation to penicillin and streptomycin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997399"}
{"pmid": "20997405", "title": "Common cases seen in the V.D. Department.", "content": "Common cases seen in the V.D. Department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997405"}
{"pmid": "20997404", "title": "Benzedrine sulphate in clinical medicine; a survey of the literature.", "content": "Benzedrine sulphate in clinical medicine; a survey of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997404"}
{"pmid": "20997406", "title": "Some danger signals in midwifery.", "content": "Some danger signals in midwifery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997406"}
{"pmid": "20997407", "title": "Recent trends in the incidence of infective fevers.", "content": "Recent trends in the incidence of infective fevers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997407"}
{"pmid": "20997408", "title": "Prophylaxis in some common fevers.", "content": "Prophylaxis in some common fevers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997408"}
{"pmid": "20997409", "title": "The treatment of the infective diseases.", "content": "The treatment of the infective diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997409"}
{"pmid": "20997410", "title": "Prognosis in the infective fevers.", "content": "Prognosis in the infective fevers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997410"}
{"pmid": "20997411", "title": "Small pox in the vaccinated.", "content": "Small pox in the vaccinated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997411"}
{"pmid": "20997412", "title": "Evaluation of the negative radiological report.", "content": "Evaluation of the negative radiological report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997412"}
{"pmid": "20997413", "title": "Ophthalmic problems in industry.", "content": "Ophthalmic problems in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997413"}
{"pmid": "20997414", "title": "Some dermatological fallacies.", "content": "Some dermatological fallacies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997414"}
{"pmid": "20997415", "title": "The early recognition of disease; the complications of pregnancy.", "content": "The early recognition of disease; the complications of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997415"}
{"pmid": "20997417", "title": "Asthma.", "content": "Asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997417"}
{"pmid": "20997416", "title": "Dysphagia.", "content": "Dysphagia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997416"}
{"pmid": "20997418", "title": "The choice of barbiturates.", "content": "The choice of barbiturates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997418"}
{"pmid": "20997428", "title": "Uremia", "content": "Uremia", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997428"}
{"pmid": "20997447", "title": "Condritis costal.", "content": "Condritis costal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997447"}
{"pmid": "20997474", "title": "Malaria following blood transfusion.", "content": "Malaria following blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997474"}
{"pmid": "20997476", "title": "Experimental purpura and pancreatic necrosis produced by Forssman heterophil antibody.", "content": "Experimental purpura and pancreatic necrosis produced by Forssman heterophil antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997476"}
{"pmid": "20997475", "title": "Evaluation of beta-dimethylaminoethyl benzhydryl ether hydrochloride (benadryl) in the treatment of urticaria, scleroderma and allied disturbances.", "content": "Evaluation of beta-dimethylaminoethyl benzhydryl ether hydrochloride (benadryl) in the treatment of urticaria, scleroderma and allied disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997475"}
{"pmid": "20997477", "title": "Annual report for 1945 of the section on anesthesiology; including data and remarks concerning blood transfusion and the use of blood substitutes.", "content": "Annual report for 1945 of the section on anesthesiology; including data and remarks concerning blood transfusion and the use of blood substitutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997477"}
{"pmid": "20997478", "title": "Treatment of allergy to insulin with benadryl.", "content": "Treatment of allergy to insulin with benadryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997478"}
{"pmid": "20997479", "title": "The fenestration operation for the restoration of hearing to conversational levels in loss of hearing due to clinical otosclerosis.", "content": "The fenestration operation for the restoration of hearing to conversational levels in loss of hearing due to clinical otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997479"}
{"pmid": "20997481", "title": "Roentgen therapy for myelogenous leukemia.", "content": "Roentgen therapy for myelogenous leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997481"}
{"pmid": "20997480", "title": "Microscopic renal calculi.", "content": "Microscopic renal calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997480"}
{"pmid": "20997483", "title": "Toxic reaction of streptomycin on the eighth nerve apparatus.", "content": "Toxic reaction of streptomycin on the eighth nerve apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997483"}
{"pmid": "20997482", "title": "Ulcer of the leg due to arteriolosclerosis and ischemia, occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers).", "content": "Ulcer of the leg due to arteriolosclerosis and ischemia, occurring in the presence of hypertensive disease (hypertensive-ischemic ulcers).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997482"}
{"pmid": "20997484", "title": "Transurethral surgery in 1945.", "content": "Transurethral surgery in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997484"}
{"pmid": "20997485", "title": "Circumcaval ureter; report of case in which diagnosis was made preoperatively.", "content": "Circumcaval ureter; report of case in which diagnosis was made preoperatively.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997485"}
{"pmid": "20997486", "title": "The treatment of major fractures.", "content": "The treatment of major fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997486"}
{"pmid": "20997487", "title": "Three fractures treated by stainless steel pins crossed at the seat of the fracture.", "content": "Three fractures treated by stainless steel pins crossed at the seat of the fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997487"}
{"pmid": "20997488", "title": "Naval medical occasions.", "content": "Naval medical occasions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997488"}
{"pmid": "20997493", "title": "Seven years experience in the convalescent care of rheumatic fever.", "content": "Seven years experience in the convalescent care of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997493"}
{"pmid": "20997494", "title": "Hemangiomas; should treatment be expectant or active?", "content": "Hemangiomas; should treatment be expectant or active?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997494"}
{"pmid": "20997495", "title": "Diethylstilbestrol in the prevention of orchitis following mumps.", "content": "Diethylstilbestrol in the prevention of orchitis following mumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997495"}
{"pmid": "20997496", "title": "Waterhouse-Friderichsen syndrome.", "content": "Waterhouse-Friderichsen syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997496"}
{"pmid": "20997497", "title": "Presidential address [health education].", "content": "Presidential address [health education].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997497"}
{"pmid": "20997498", "title": "Surgical treatment of pituitary adenoma.", "content": "Surgical treatment of pituitary adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997498"}
{"pmid": "20997500", "title": "Treatment of herpes zoster with contramine.", "content": "Treatment of herpes zoster with contramine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997500"}
{"pmid": "20997499", "title": "A plague survey of Ngamiland, Bechuanaland Protectorate, during the epidemic of 1944-45.", "content": "A plague survey of Ngamiland, Bechuanaland Protectorate, during the epidemic of 1944-45.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997499"}
{"pmid": "20997501", "title": "Induction of labour by puncture of membranes.", "content": "Induction of labour by puncture of membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997501"}
{"pmid": "20997503", "title": "The treatment of pink disease (erythroedema).", "content": "The treatment of pink disease (erythroedema).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997503"}
{"pmid": "20997502", "title": "A case of severe septic wound of the left lower leg treated with small deep grafts.", "content": "A case of severe septic wound of the left lower leg treated with small deep grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997502"}
{"pmid": "20997504", "title": "Cooley's (Mediterranean) anaemia in a South African-born European adolescent.", "content": "Cooley's (Mediterranean) anaemia in a South African-born European adolescent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997504"}
{"pmid": "20997505", "title": "Fenestration for otosclerosis.", "content": "Fenestration for otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997505"}
{"pmid": "20997506", "title": "STRANGE drop in efficacy of penicillin; factors responsible under study.", "content": "STRANGE drop in efficacy of penicillin; factors responsible under study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997506"}
{"pmid": "20997507", "title": "Hypertension of renal origin.", "content": "Hypertension of renal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997507"}
{"pmid": "20997508", "title": "Bacterial endocarditis of the tricuspid valve.", "content": "Bacterial endocarditis of the tricuspid valve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997508"}
{"pmid": "20997509", "title": "Tularemia; treatment of a case with streptomycin.", "content": "Tularemia; treatment of a case with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997509"}
{"pmid": "20997510", "title": "The treatment of herpes zoster.", "content": "The treatment of herpes zoster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997510"}
{"pmid": "20997511", "title": "Spontaneous rupture of the kidney.", "content": "Spontaneous rupture of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997511"}
{"pmid": "20997513", "title": "A psychosomatic evaluation of the psychiatric and endocrinological factors in the menopause.", "content": "A psychosomatic evaluation of the psychiatric and endocrinological factors in the menopause.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997513"}
{"pmid": "20997512", "title": "Volvulus of the stomach.", "content": "Volvulus of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997512"}
{"pmid": "20997514", "title": "A comparison of the effectiveness of radiation therapy and estrogenic substances in the management of hyperthyroidism.", "content": "A comparison of the effectiveness of radiation therapy and estrogenic substances in the management of hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997514"}
{"pmid": "20997515", "title": "Vein ligation in thrombophlebitis.", "content": "Vein ligation in thrombophlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997515"}
{"pmid": "20997516", "title": "The value of influenza virus vaccine, types A and B.", "content": "The value of influenza virus vaccine, types A and B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997516"}
{"pmid": "20997517", "title": "Effect of vitamin A administration upon defective color vision.", "content": "Effect of vitamin A administration upon defective color vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997517"}
{"pmid": "20997518", "title": "Report of a case of aortic aneurysm rupturing into the superior vena cava.", "content": "Report of a case of aortic aneurysm rupturing into the superior vena cava.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997518"}
{"pmid": "20997519", "title": "Surgical relief of post-traumatic pain.", "content": "Surgical relief of post-traumatic pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997519"}
{"pmid": "20997520", "title": "Relations between immediate and delayed skin reactions.", "content": "Relations between immediate and delayed skin reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997520"}
{"pmid": "20997521", "title": "Diagnosis of liver abscess by means of thorotrast hepatosplenography.", "content": "Diagnosis of liver abscess by means of thorotrast hepatosplenography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997521"}
{"pmid": "20997522", "title": "Para-amino-benzoic acid in the treatment of endemic typhus fever.", "content": "Para-amino-benzoic acid in the treatment of endemic typhus fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997522"}
{"pmid": "20997523", "title": "Prostigmine usage in pediatrics.", "content": "Prostigmine usage in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997523"}
{"pmid": "20997524", "title": "Water in relation to health problems in children in Texas.", "content": "Water in relation to health problems in children in Texas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997524"}
{"pmid": "20997525", "title": "Cleaning traumatic wounds by multiple fine-stream pressure irrigation; an improved method.", "content": "Cleaning traumatic wounds by multiple fine-stream pressure irrigation; an improved method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997525"}
{"pmid": "20997526", "title": "Management of prostatic surgery in the aged.", "content": "Management of prostatic surgery in the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997526"}
{"pmid": "20997527", "title": "Primary carcinoma of the gallbladder.", "content": "Primary carcinoma of the gallbladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997527"}
{"pmid": "20997528", "title": "Fungus infections of the cornea; case report of keratomycosis due to monilia.", "content": "Fungus infections of the cornea; case report of keratomycosis due to monilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997528"}
{"pmid": "20997529", "title": "An epidemiological investigation of typhus fever in Texas, 1943-1945.", "content": "An epidemiological investigation of typhus fever in Texas, 1943-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997529"}
{"pmid": "20997530", "title": "Teamwork in cancer control.", "content": "Teamwork in cancer control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997530"}
{"pmid": "20997535", "title": "Brain modelling.", "content": "Brain modelling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997535"}
{"pmid": "20997536", "title": "Pharmacological action of aminophylline.", "content": "Pharmacological action of aminophylline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997536"}
{"pmid": "20997537", "title": "Aminophylline in relation to heart pain.", "content": "Aminophylline in relation to heart pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997537"}
{"pmid": "20997538", "title": "The pharmacology of penicillin.", "content": "The pharmacology of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997538"}
{"pmid": "20997540", "title": "Pulmonary actinomycosis.", "content": "Pulmonary actinomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997540"}
{"pmid": "20997539", "title": "Possible Waterhouse-Friderichsen syndrome with recovery.", "content": "Possible Waterhouse-Friderichsen syndrome with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997539"}
{"pmid": "20997532", "title": "Cancer of the cervix.", "content": "Cancer of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997532"}
{"pmid": "20997531", "title": "Injuries to the chest wall and intrathoracic structures.", "content": "Injuries to the chest wall and intrathoracic structures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997531"}
{"pmid": "20997541", "title": "NOBEL Prize winners in physiology and medicine.", "content": "NOBEL Prize winners in physiology and medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997541"}
{"pmid": "20997533", "title": "Sudden death.", "content": "Sudden death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997533"}
{"pmid": "20997542", "title": "A glimpse at the development of immunology and allergy in the light of the contribution of six Nobel Prize winners; von Behring, Richet, Bordet, Metchnikoff, Landsteiner, Koch.", "content": "A glimpse at the development of immunology and allergy in the light of the contribution of six Nobel Prize winners; von Behring, Richet, Bordet, Metchnikoff, Landsteiner, Koch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997542"}
{"pmid": "20997545", "title": "A review of one hundred and twenty-nine consecutive cases of tuberculosis treated with pneumothorax over a ten year period.", "content": "A review of one hundred and twenty-nine consecutive cases of tuberculosis treated with pneumothorax over a ten year period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997545"}
{"pmid": "20997543", "title": "Historical aspects of infectious diseases.", "content": "Historical aspects of infectious diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997543"}
{"pmid": "20997544", "title": "Making a correct diagnosis; its importance and problems.", "content": "Making a correct diagnosis; its importance and problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997544"}
{"pmid": "20997546", "title": "Needed; a state health council for voluntary health agencies.", "content": "Needed; a state health council for voluntary health agencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997546"}
{"pmid": "20997534", "title": "Carcinoma of the rectum.", "content": "Carcinoma of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997534"}
{"pmid": "20997547", "title": "HEMORRHAGE and obstetric mortality.", "content": "HEMORRHAGE and obstetric mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997547"}
{"pmid": "20997548", "title": "True infective abacterial pyuria.", "content": "True infective abacterial pyuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997548"}
{"pmid": "20997549", "title": "Brucellosis at the State of Wisconsin General Hospital.", "content": "Brucellosis at the State of Wisconsin General Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997549"}
{"pmid": "20997550", "title": "The interpretation of the agglutination test.", "content": "The interpretation of the agglutination test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997550"}
{"pmid": "20997551", "title": "Further studies on the use of tantalum for cranioplasties.", "content": "Further studies on the use of tantalum for cranioplasties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997551"}
{"pmid": "20997552", "title": "A simplified technique for the fabrication of tantalum skull plates.", "content": "A simplified technique for the fabrication of tantalum skull plates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997552"}
{"pmid": "20997553", "title": "Studies on new insect repellents.", "content": "Studies on new insect repellents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997553"}
{"pmid": "20997554", "title": "An achievement of Navy peacetime medicine.", "content": "An achievement of Navy peacetime medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997554"}
{"pmid": "20997555", "title": "The prevention and treatment of aerotitis media.", "content": "The prevention and treatment of aerotitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997555"}
{"pmid": "20997556", "title": "Radium therapy in aerotitis media.", "content": "Radium therapy in aerotitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997556"}
{"pmid": "20997558", "title": "Neurosurgery on board an attack transport (hospital).", "content": "Neurosurgery on board an attack transport (hospital).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997558"}
{"pmid": "20997557", "title": "The significance of Hanger's test (cephalin-cholesterol flocculation test) in disorders of the stomach and colon.", "content": "The significance of Hanger's test (cephalin-cholesterol flocculation test) in disorders of the stomach and colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997557"}
{"pmid": "20997559", "title": "Influenza aboard an attack transport.", "content": "Influenza aboard an attack transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997559"}
{"pmid": "20997560", "title": "Diet aboard an auxiliary ship.", "content": "Diet aboard an auxiliary ship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997560"}
{"pmid": "20997561", "title": "The usefulness of the Cornell Selectee Index at the neuropsychiatric unit of a naval training center.", "content": "The usefulness of the Cornell Selectee Index at the neuropsychiatric unit of a naval training center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997561"}
{"pmid": "20997562", "title": "Intestinal parasitism; a statistical study on 1,000 patients recently returned from Pacific area duty.", "content": "Intestinal parasitism; a statistical study on 1,000 patients recently returned from Pacific area duty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997562"}
{"pmid": "20997563", "title": "Spontaneous pneumothorax.", "content": "Spontaneous pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997563"}
{"pmid": "20997564", "title": "Secondary infection of dermatophytosis.", "content": "Secondary infection of dermatophytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997564"}
{"pmid": "20997565", "title": "Syphilitic reinfection after treatment with penicillin.", "content": "Syphilitic reinfection after treatment with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997565"}
{"pmid": "20997566", "title": "Localized amyloidosis of the urinary bladder.", "content": "Localized amyloidosis of the urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997566"}
{"pmid": "20997567", "title": "Traumatic arteriovenous fistula of the superficial temporal artery and vein.", "content": "Traumatic arteriovenous fistula of the superficial temporal artery and vein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997567"}
{"pmid": "20997568", "title": "The ectopic kidney with a presentation of five case reports.", "content": "The ectopic kidney with a presentation of five case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997568"}
{"pmid": "20997569", "title": "Construction and use of bed gymnasium.", "content": "Construction and use of bed gymnasium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997569"}
{"pmid": "20997570", "title": "The rat population of a newly established military base in the Solomon Islands.", "content": "The rat population of a newly established military base in the Solomon Islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997570"}
{"pmid": "20997573", "title": "Position effect and the theory of the corpuscular gene.", "content": "Position effect and the theory of the corpuscular gene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997573"}
{"pmid": "20997578", "title": "The biology of Cynaeus angustus Lec., a new stored grain pest.", "content": "The biology of Cynaeus angustus Lec., a new stored grain pest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997578"}
{"pmid": "20997579", "title": "A combined field and laboratory process for the estimation of plasma atabrine levels in field troops from single samples of urine.", "content": "A combined field and laboratory process for the estimation of plasma atabrine levels in field troops from single samples of urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997579"}
{"pmid": "20997580", "title": "Antibiotics in a polyporus (Polystictus sanguineus).", "content": "Antibiotics in a polyporus (Polystictus sanguineus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997580"}
{"pmid": "20997581", "title": "The velocity of sound; a molecular property.", "content": "The velocity of sound; a molecular property.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997581"}
{"pmid": "20997582", "title": "Fixation area in the human eye.", "content": "Fixation area in the human eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997582"}
{"pmid": "20997583", "title": "Ageing of nerve cells.", "content": "Ageing of nerve cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997583"}
{"pmid": "20997584", "title": "Urease in the gastric mucosa and its increase after a meat diet, soya bean flour diet or urogastrone infections.", "content": "Urease in the gastric mucosa and its increase after a meat diet, soya bean flour diet or urogastrone infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997584"}
{"pmid": "20997585", "title": "Conditioned pyridoxine deficiency in rats on diets containing flours of different extraction-rates.", "content": "Conditioned pyridoxine deficiency in rats on diets containing flours of different extraction-rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997585"}
{"pmid": "20997586", "title": "Electrolytic detection of small amounts of lead in brass or zinc.", "content": "Electrolytic detection of small amounts of lead in brass or zinc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997586"}
{"pmid": "20997587", "title": "Occurrence in human serum of yellow substances different from bilirubin.", "content": "Occurrence in human serum of yellow substances different from bilirubin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997587"}
{"pmid": "20997588", "title": "ERADICATION of tuberculosis in cattle.", "content": "ERADICATION of tuberculosis in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997588"}
{"pmid": "20997589", "title": "Ultra-micro methods in nuclear chemistry.", "content": "Ultra-micro methods in nuclear chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997589"}
{"pmid": "20997591", "title": "Anthocyanins of gladiolus.", "content": "Anthocyanins of gladiolus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997591"}
{"pmid": "20997590", "title": "CENTENARY of the Smithsonian Institution.", "content": "CENTENARY of the Smithsonian Institution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997590"}
{"pmid": "20997592", "title": "Demonstration of an agglutinin to Trichomonas foetus in vaginal mucus.", "content": "Demonstration of an agglutinin to Trichomonas foetus in vaginal mucus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997592"}
{"pmid": "20997593", "title": "Electrocardiogram of the embryo at the beginning of the contractile function of the heart and of explants cultivated in vitro.", "content": "Electrocardiogram of the embryo at the beginning of the contractile function of the heart and of explants cultivated in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997593"}
{"pmid": "20997594", "title": "Industrial spectroscopy.", "content": "Industrial spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997594"}
{"pmid": "20997595", "title": "Deterioration on storage of dried skim milk.", "content": "Deterioration on storage of dried skim milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997595"}
{"pmid": "20997596", "title": "VITAMIN B and fat anabolism.", "content": "VITAMIN B and fat anabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997596"}
{"pmid": "20997597", "title": "Purification and adsorption of diphtheria toxoid.", "content": "Purification and adsorption of diphtheria toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997597"}
{"pmid": "20997598", "title": "SCIENTIFIC information services.", "content": "SCIENTIFIC information services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997598"}
{"pmid": "20997599", "title": "Heredity and variation in micro-organisms.", "content": "Heredity and variation in micro-organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997599"}
{"pmid": "20997600", "title": "Russian work on chemical induction in adult animals.", "content": "Russian work on chemical induction in adult animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997600"}
{"pmid": "20997601", "title": "Specific inhibition of esterase in ester-hydrolysing enzyme systems.", "content": "Specific inhibition of esterase in ester-hydrolysing enzyme systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997601"}
{"pmid": "20997602", "title": "Crystallization of arginase.", "content": "Crystallization of arginase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997602"}
{"pmid": "20997603", "title": "Transformations of the retinal ganglionic cells in tissue cultures.", "content": "Transformations of the retinal ganglionic cells in tissue cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997603"}
{"pmid": "20997604", "title": "Lethal effects of D.D.T. on young fish.", "content": "Lethal effects of D.D.T. on young fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997604"}
{"pmid": "20997605", "title": "The perfect state of Botrytis squamosa Walker.", "content": "The perfect state of Botrytis squamosa Walker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997605"}
{"pmid": "20997606", "title": "Glycol splitting by hydroxyl radicals.", "content": "Glycol splitting by hydroxyl radicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997606"}
{"pmid": "20997607", "title": "Hydrolysis of chloral in heavy hydrogen water.", "content": "Hydrolysis of chloral in heavy hydrogen water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997607"}
{"pmid": "20997608", "title": "Influences on dental defects in naval personnel.", "content": "Influences on dental defects in naval personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997608"}
{"pmid": "20997609", "title": "Interactions between proteins and azosulfonamides.", "content": "Interactions between proteins and azosulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997609"}
{"pmid": "20997610", "title": "Two new effective insect repellents, NMRI-201 and NMRI-448.", "content": "Two new effective insect repellents, NMRI-201 and NMRI-448.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997610"}
{"pmid": "20997611", "title": "ARMY Institute of Pathology and American Registry of Pathology.", "content": "ARMY Institute of Pathology and American Registry of Pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997611"}
{"pmid": "20997612", "title": "The composition of streptomycin Reineckate.", "content": "The composition of streptomycin Reineckate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997612"}
{"pmid": "20997613", "title": "Infrared emission spectra of liquids.", "content": "Infrared emission spectra of liquids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997613"}
{"pmid": "20997614", "title": "Dropping device for cylinder plate assay of penicillin.", "content": "Dropping device for cylinder plate assay of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997614"}
{"pmid": "20997615", "title": "Prior use of the Rutherford Unit.", "content": "Prior use of the Rutherford Unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997615"}
{"pmid": "20997616", "title": "The Rh system in the chimpanzee.", "content": "The Rh system in the chimpanzee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997616"}
{"pmid": "20997617", "title": "Inhibition of surface growth.", "content": "Inhibition of surface growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997617"}
{"pmid": "20997618", "title": "Presence and action of acetylcholine in experimental brain trauma.", "content": "Presence and action of acetylcholine in experimental brain trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997618"}
{"pmid": "20997619", "title": "The relation of electric potential changes to contracture in skeletal muscle.", "content": "The relation of electric potential changes to contracture in skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997619"}
{"pmid": "20997620", "title": "Righting and other postural activity in low-decerebrate and in spinal cats after d-amphetamine.", "content": "Righting and other postural activity in low-decerebrate and in spinal cats after d-amphetamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997620"}
{"pmid": "20997621", "title": "Stimulation with minimum power.", "content": "Stimulation with minimum power.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997621"}
{"pmid": "20997622", "title": "Responses of single human motor units to electrical stimulation.", "content": "Responses of single human motor units to electrical stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997622"}
{"pmid": "20997623", "title": "Natural and artificial activation of motor units; a comparison.", "content": "Natural and artificial activation of motor units; a comparison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997623"}
{"pmid": "20997624", "title": "Competitive reinnervation of rat muscles by their own and foreign nerves.", "content": "Competitive reinnervation of rat muscles by their own and foreign nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997624"}
{"pmid": "20997625", "title": "A method of resolving acute catatonic excitement.", "content": "A method of resolving acute catatonic excitement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997625"}
{"pmid": "20997626", "title": "Carl Gustav Jung; defender of Freud and the Jews; a chapter of European psychiatric history under the Nazi yoke.", "content": "Carl Gustav Jung; defender of Freud and the Jews; a chapter of European psychiatric history under the Nazi yoke.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997626"}
{"pmid": "20997627", "title": "Benign intracranial space-occupying masses simulating mental disorders.", "content": "Benign intracranial space-occupying masses simulating mental disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997627"}
{"pmid": "20997628", "title": "The lure of the supernatural.", "content": "The lure of the supernatural.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997628"}
{"pmid": "20997629", "title": "Fear.", "content": "Fear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997629"}
{"pmid": "20997630", "title": "Management of psychiatric patients in the combat area.", "content": "Management of psychiatric patients in the combat area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997630"}
{"pmid": "20997631", "title": "Psychopathology of compulsive smoking.", "content": "Psychopathology of compulsive smoking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997631"}
{"pmid": "20997633", "title": "ROOT of our evils; a sensitive, intelligent patient views a state hospital.", "content": "ROOT of our evils; a sensitive, intelligent patient views a state hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997633"}
{"pmid": "20997632", "title": "Group therapy in an extramural clinic.", "content": "Group therapy in an extramural clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997632"}
{"pmid": "20997634", "title": "The regression of psychiatry in the Army.", "content": "The regression of psychiatry in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997634"}
{"pmid": "20997635", "title": "Something about a soldier.", "content": "Something about a soldier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997635"}
{"pmid": "20997636", "title": "Psychiatric casualties from Guadalcanal, a study of reactions to extreme stress.", "content": "Psychiatric casualties from Guadalcanal, a study of reactions to extreme stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997636"}
{"pmid": "20997637", "title": "Some observations on character structure in the Orient; the Chinese.", "content": "Some observations on character structure in the Orient; the Chinese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997637"}
{"pmid": "20997640", "title": "The psychiatrist's job in war and peace.", "content": "The psychiatrist's job in war and peace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997640"}
{"pmid": "20997639", "title": "Determinism, freedom and psychotherapy.", "content": "Determinism, freedom and psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997639"}
{"pmid": "20997638", "title": "Ormsby village; an experiment with forced psychotherapy in the rehabilitation of the delinquent adolescent.", "content": "Ormsby village; an experiment with forced psychotherapy in the rehabilitation of the delinquent adolescent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997638"}
{"pmid": "20997646", "title": "Treatment of glaucoma with di-isopropyl fluorophosphate.", "content": "Treatment of glaucoma with di-isopropyl fluorophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997646"}
{"pmid": "20997647", "title": "Indications and contraindications for keratoplasty and keratectomies.", "content": "Indications and contraindications for keratoplasty and keratectomies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997647"}
{"pmid": "20997648", "title": "Arsenical eye burns.", "content": "Arsenical eye burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997648"}
{"pmid": "20997649", "title": "A device for group demonstration of astigmatism tests.", "content": "A device for group demonstration of astigmatism tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997649"}
{"pmid": "20997650", "title": "Cultivation of human tumor in the anterior chamber of the guinea-pig's eye.", "content": "Cultivation of human tumor in the anterior chamber of the guinea-pig's eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997650"}
{"pmid": "20997651", "title": "Corneal ulcer treated with streptomycin.", "content": "Corneal ulcer treated with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997651"}
{"pmid": "20997652", "title": "Legal ophthalmology.", "content": "Legal ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997652"}
{"pmid": "20997653", "title": "General anesthesia in ophthalmic surgery.", "content": "General anesthesia in ophthalmic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997653"}
{"pmid": "20997654", "title": "Keratoconjunctivitis sicca; a sequela to purulent erythema exudativum multiforme (Stevens-Johnson's disease).", "content": "Keratoconjunctivitis sicca; a sequela to purulent erythema exudativum multiforme (Stevens-Johnson's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997654"}
{"pmid": "20997656", "title": "Infections and reflex disorders of the eye from dental affections.", "content": "Infections and reflex disorders of the eye from dental affections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997656"}
{"pmid": "20997655", "title": "A comparative study of sutures employed in surgery of the extraocular muscles.", "content": "A comparative study of sutures employed in surgery of the extraocular muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997655"}
{"pmid": "20997657", "title": "Conjunctivitis associated with erythema multiforme bullosa.", "content": "Conjunctivitis associated with erythema multiforme bullosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997657"}
{"pmid": "20997658", "title": "Retinal venous sheathing in multiple sclerosis.", "content": "Retinal venous sheathing in multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997658"}
{"pmid": "20997659", "title": "Tantalum enucleation implant.", "content": "Tantalum enucleation implant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997659"}
{"pmid": "20997660", "title": "Penetrating wounds of the cornea with hypopyon treated with penicillin.", "content": "Penetrating wounds of the cornea with hypopyon treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997660"}
{"pmid": "20997662", "title": "Glaucoma; some suggested etiologic factors.", "content": "Glaucoma; some suggested etiologic factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997662"}
{"pmid": "20997661", "title": "The role of glasses, amblyopia, orthoptics, and surgery in the treatment of strabismus.", "content": "The role of glasses, amblyopia, orthoptics, and surgery in the treatment of strabismus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997661"}
{"pmid": "20997663", "title": "Experiences in scleral resection.", "content": "Experiences in scleral resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997663"}
{"pmid": "20997664", "title": "Ocular drainage.", "content": "Ocular drainage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997664"}
{"pmid": "20997665", "title": "Pupillography in the early diagnosis of chronic simple glaucoma.", "content": "Pupillography in the early diagnosis of chronic simple glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997665"}
{"pmid": "20997666", "title": "Tenonitis complicating mumps.", "content": "Tenonitis complicating mumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997666"}
{"pmid": "20997667", "title": "Changes in lens of embryo after rubella; microscopic examination of eight week old embryo.", "content": "Changes in lens of embryo after rubella; microscopic examination of eight week old embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997667"}
{"pmid": "20997668", "title": "Night vision; a comparison of the scotopic visual ratings of young Japanese and Caucasian adults living in Hawaii.", "content": "Night vision; a comparison of the scotopic visual ratings of young Japanese and Caucasian adults living in Hawaii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997668"}
{"pmid": "20997669", "title": "Depth perception and flying ability.", "content": "Depth perception and flying ability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997669"}
{"pmid": "20997670", "title": "Clinical aspects of stereopsis.", "content": "Clinical aspects of stereopsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997670"}
{"pmid": "20997671", "title": "Alkali burns of the eye; clinical and pathologic course.", "content": "Alkali burns of the eye; clinical and pathologic course.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997671"}
{"pmid": "20997672", "title": "Animal operating equipment for experimental ocular surgery.", "content": "Animal operating equipment for experimental ocular surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997672"}
{"pmid": "20997673", "title": "Scotoma as a complication of decompression sickness.", "content": "Scotoma as a complication of decompression sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997673"}
{"pmid": "20997674", "title": "Instrument for locating retinal ruptures during operation.", "content": "Instrument for locating retinal ruptures during operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997674"}
{"pmid": "20997675", "title": "Clostridium welchii panophthalmitis.", "content": "Clostridium welchii panophthalmitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997675"}
{"pmid": "20997676", "title": "Thiamine (vitamin B1) in ophthalmology.", "content": "Thiamine (vitamin B1) in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997676"}
{"pmid": "20997677", "title": "Management of vertical deviation.", "content": "Management of vertical deviation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997677"}
{"pmid": "20997678", "title": "Operation for oxycephaly with exophthalmos.", "content": "Operation for oxycephaly with exophthalmos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997678"}
{"pmid": "20997679", "title": "Tendon transplantation for paralysis of the external rectus muscle.", "content": "Tendon transplantation for paralysis of the external rectus muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997679"}
{"pmid": "20997680", "title": "Nineteenth century provincial eye hospitals (with special reference to those no longer extant).", "content": "Nineteenth century provincial eye hospitals (with special reference to those no longer extant).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997680"}
{"pmid": "20997681", "title": "Notes on eye (or eye and ear) institutions no longer extant.", "content": "Notes on eye (or eye and ear) institutions no longer extant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997681"}
{"pmid": "20997682", "title": "Biographical notes on ophthalmologists.", "content": "Biographical notes on ophthalmologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997682"}
{"pmid": "20997683", "title": "Bilateral symmetrical cystic detachment of the retina.", "content": "Bilateral symmetrical cystic detachment of the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997683"}
{"pmid": "20997684", "title": "Pterygium; its nature and a new line of treatment.", "content": "Pterygium; its nature and a new line of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997684"}
{"pmid": "20997685", "title": "Speech after laryngectomy.", "content": "Speech after laryngectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997685"}
{"pmid": "20997686", "title": "Infant speech equations for consonant-vowel ratios.", "content": "Infant speech equations for consonant-vowel ratios.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997686"}
{"pmid": "20997687", "title": "Malingering and psychogenic deafness.", "content": "Malingering and psychogenic deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997687"}
{"pmid": "20997688", "title": "Myasthenia laryngis.", "content": "Myasthenia laryngis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997688"}
{"pmid": "20997689", "title": "Psychogenesis in interdental sigmatism.", "content": "Psychogenesis in interdental sigmatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997689"}
{"pmid": "20997690", "title": "French-English speech terminology.", "content": "French-English speech terminology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997690"}
{"pmid": "20997691", "title": "Differential diagnosis of aphasia in children.", "content": "Differential diagnosis of aphasia in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997691"}
{"pmid": "20997692", "title": "A speech pathologist's professional code.", "content": "A speech pathologist's professional code.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997692"}
{"pmid": "20997693", "title": "Speech disorders in World War II; organization of a speech clinic in an Army general hospital.", "content": "Speech disorders in World War II; organization of a speech clinic in an Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997693"}
{"pmid": "20997695", "title": "What is Nystagmusbereitschaft?", "content": "What is Nystagmusbereitschaft?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997695"}
{"pmid": "20997696", "title": "Loss of hearing and tuba-stenosis in children.", "content": "Loss of hearing and tuba-stenosis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997696"}
{"pmid": "20997699", "title": "Periosteal reaction, fever and irritability in young infants; a new syndrome?", "content": "Periosteal reaction, fever and irritability in young infants; a new syndrome?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997699"}
{"pmid": "20997700", "title": "Causes of death of children on the Isthmus of Panama.", "content": "Causes of death of children on the Isthmus of Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997700"}
{"pmid": "20997701", "title": "Angles of clearance; a method for measuring the cardiac size of children with rheumatic heart disease.", "content": "Angles of clearance; a method for measuring the cardiac size of children with rheumatic heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997701"}
{"pmid": "20997702", "title": "Meckel's diverticulum; a consideration of the anomaly, with a review of sixty-one cases.", "content": "Meckel's diverticulum; a consideration of the anomaly, with a review of sixty-one cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997702"}
{"pmid": "20997704", "title": "Acute suppurative parotitis in a newborn premature infant.", "content": "Acute suppurative parotitis in a newborn premature infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997704"}
{"pmid": "20997703", "title": "Causes of prematurity; influence of toxemia on the incidence of prematurity.", "content": "Causes of prematurity; influence of toxemia on the incidence of prematurity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997703"}
{"pmid": "20997705", "title": "Gastric phase of milk digestion in childhood.", "content": "Gastric phase of milk digestion in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997705"}
{"pmid": "20997706", "title": "Cystic fibrosis of the pancreas in twins.", "content": "Cystic fibrosis of the pancreas in twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997706"}
{"pmid": "20997707", "title": "Methionine in the control of bleeding and restoration of normal clot retraction in purpura following scarlet fever.", "content": "Methionine in the control of bleeding and restoration of normal clot retraction in purpura following scarlet fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997707"}
{"pmid": "20997708", "title": "Two cases of Waterhouse-Friderichsen syndrome in the same family, one with recovery under penicillin therapy.", "content": "Two cases of Waterhouse-Friderichsen syndrome in the same family, one with recovery under penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997708"}
{"pmid": "20997709", "title": "The evolution of intubation.", "content": "The evolution of intubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997709"}
{"pmid": "20997710", "title": "Lupus erythematosus.", "content": "Lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997710"}
{"pmid": "20997711", "title": "Mumps; pretracheal edema.", "content": "Mumps; pretracheal edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997711"}
{"pmid": "20997746", "title": "The porphyrin requirements of Haemophilus influenzae and some functions of the vinyl and propionic acid side chains of heme.", "content": "The porphyrin requirements of Haemophilus influenzae and some functions of the vinyl and propionic acid side chains of heme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997746"}
{"pmid": "20997747", "title": "Hemolytic systems containing anionic detergents.", "content": "Hemolytic systems containing anionic detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997747"}
{"pmid": "20997748", "title": "Further observations on the mechanism of phage action.", "content": "Further observations on the mechanism of phage action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997748"}
{"pmid": "20997749", "title": "Fractionation of the eye pigments of Drosophila melanogaster.", "content": "Fractionation of the eye pigments of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997749"}
{"pmid": "20997750", "title": "Nature of the action current in Nitella; simple and complex action patterns.", "content": "Nature of the action current in Nitella; simple and complex action patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997750"}
{"pmid": "20997751", "title": "Effects of certain limiting conditions on the synthesis of B vitamins by yeast.", "content": "Effects of certain limiting conditions on the synthesis of B vitamins by yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997751"}
{"pmid": "20997752", "title": "The pyruvate metabolism of sea urchin eggs during the process of cell division.", "content": "The pyruvate metabolism of sea urchin eggs during the process of cell division.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997752"}
{"pmid": "20997753", "title": "Optochiasmatic arachnoiditis.", "content": "Optochiasmatic arachnoiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997753"}
{"pmid": "20997754", "title": "Some observations concerning the hypophysial fossa.", "content": "Some observations concerning the hypophysial fossa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997754"}
{"pmid": "20997755", "title": "The roentgenographic appearance of the falx cerebri.", "content": "The roentgenographic appearance of the falx cerebri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997755"}
{"pmid": "20997756", "title": "Primary atypical pneumonia; a disease of segmental distribution.", "content": "Primary atypical pneumonia; a disease of segmental distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997756"}
{"pmid": "20997757", "title": "Roentgenologic studies on the effect of synthetic folic acid on the gastrointestinal tract of patients with tropical sprue.", "content": "Roentgenologic studies on the effect of synthetic folic acid on the gastrointestinal tract of patients with tropical sprue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997757"}
{"pmid": "20997758", "title": "Reticulo-endotheliosis.", "content": "Reticulo-endotheliosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997758"}
{"pmid": "20997759", "title": "Roentgenological examination of the power of resistance of the tracheal wall; an important sign in treatment of tracheal stenosis.", "content": "Roentgenological examination of the power of resistance of the tracheal wall; an important sign in treatment of tracheal stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997759"}
{"pmid": "20997760", "title": "A new medium for cystourethrography.", "content": "A new medium for cystourethrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997760"}
{"pmid": "20997761", "title": "Treatment of peritendinitis calcarea of the shoulder joint by roentgen irradiation.", "content": "Treatment of peritendinitis calcarea of the shoulder joint by roentgen irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997761"}
{"pmid": "20997762", "title": "Simplification of tissue dose estimation in roentgen therapy.", "content": "Simplification of tissue dose estimation in roentgen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997762"}
{"pmid": "20997763", "title": "The genetic effects of radiations.", "content": "The genetic effects of radiations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997763"}
{"pmid": "20997770", "title": "External therapeutic use of radioactive phosphorus; erythema studies.", "content": "External therapeutic use of radioactive phosphorus; erythema studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997770"}
{"pmid": "20997771", "title": "The bone changes of leukemia in children.", "content": "The bone changes of leukemia in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997771"}
{"pmid": "20997772", "title": "A radiographic chest survey of patients from the Dachau Concentration Camp.", "content": "A radiographic chest survey of patients from the Dachau Concentration Camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997772"}
{"pmid": "20997773", "title": "A new roentgen sign in extrahepatic biliary tract disease.", "content": "A new roentgen sign in extrahepatic biliary tract disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997773"}
{"pmid": "20997774", "title": "A radiographic study of spondylolisthesis with special reference to stability determination.", "content": "A radiographic study of spondylolisthesis with special reference to stability determination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997774"}
{"pmid": "20997775", "title": "Energy absorption and integral dose in x-ray and radium therapy; a review.", "content": "Energy absorption and integral dose in x-ray and radium therapy; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997775"}
{"pmid": "20997776", "title": "Osteopoikilosis; report of two cases.", "content": "Osteopoikilosis; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997776"}
{"pmid": "20997777", "title": "Roentgen diagnosis of ascariasis in the alimentary tract.", "content": "Roentgen diagnosis of ascariasis in the alimentary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997777"}
{"pmid": "20997778", "title": "Symmetrical renal rotation about the vertical axis.", "content": "Symmetrical renal rotation about the vertical axis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997778"}
{"pmid": "20997779", "title": "The dose of radiation.", "content": "The dose of radiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997779"}
{"pmid": "20997780", "title": "Importance of sulfhydryl in the treatment of corneal and X-ray burns.", "content": "Importance of sulfhydryl in the treatment of corneal and X-ray burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997780"}
{"pmid": "20997781", "title": "Total excision of the patella for fracture.", "content": "Total excision of the patella for fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997781"}
{"pmid": "20997782", "title": "Anorectal abscesses.", "content": "Anorectal abscesses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997782"}
{"pmid": "20997783", "title": "Distal ectopic pregnancy; implantation of the ovum in the cervical mucosa.", "content": "Distal ectopic pregnancy; implantation of the ovum in the cervical mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997783"}
{"pmid": "20997784", "title": "A comparison of silk and nylon as suture material.", "content": "A comparison of silk and nylon as suture material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997784"}
{"pmid": "20997785", "title": "Management of sharp pointed foreign bodies in the gastrointestinal tract.", "content": "Management of sharp pointed foreign bodies in the gastrointestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997785"}
{"pmid": "20997786", "title": "Why hernias recur.", "content": "Why hernias recur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997786"}
{"pmid": "20997787", "title": "Vascular trauma.", "content": "Vascular trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997787"}
{"pmid": "20997788", "title": "Traumatic hemothorax.", "content": "Traumatic hemothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997788"}
{"pmid": "20997789", "title": "The transverse incision in abdominal surgery; a 5-year study.", "content": "The transverse incision in abdominal surgery; a 5-year study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997789"}
{"pmid": "20997791", "title": "Blood cell jel for chronic surface ulcers.", "content": "Blood cell jel for chronic surface ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997791"}
{"pmid": "20997790", "title": "Non-infectious iliopectineal bursitis.", "content": "Non-infectious iliopectineal bursitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997790"}
{"pmid": "20997792", "title": "Diagnosis of thenar space abscess.", "content": "Diagnosis of thenar space abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997792"}
{"pmid": "20997793", "title": "Carcinoma of the cecum in association with acute appendicitis.", "content": "Carcinoma of the cecum in association with acute appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997793"}
{"pmid": "20997794", "title": "Embryonal tumors of kidney in infancy and childhood.", "content": "Embryonal tumors of kidney in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997794"}
{"pmid": "20997795", "title": "A modified Whipple operation for carcinoma at the ampulla of Vater.", "content": "A modified Whipple operation for carcinoma at the ampulla of Vater.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997795"}
{"pmid": "20997796", "title": "Congenital hernia in a male containing a rudimentary uterus.", "content": "Congenital hernia in a male containing a rudimentary uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997796"}
{"pmid": "20997798", "title": "Perforated gastroduodenal ulcers.", "content": "Perforated gastroduodenal ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997798"}
{"pmid": "20997797", "title": "Traumatic rupture of a hydrocele sac.", "content": "Traumatic rupture of a hydrocele sac.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997797"}
{"pmid": "20997800", "title": "Familial diverticulosis of the colon; report of seven cases in one family of nine persons.", "content": "Familial diverticulosis of the colon; report of seven cases in one family of nine persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997800"}
{"pmid": "20997799", "title": "Congenital stenosis of small intestine; with retention of nonpenetrating foreign bodies.", "content": "Congenital stenosis of small intestine; with retention of nonpenetrating foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997799"}
{"pmid": "20997801", "title": "Carcinoma of Meckel's diverticulum.", "content": "Carcinoma of Meckel's diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997801"}
{"pmid": "20997802", "title": "Enterogenous cysts; report of case involving the rectum.", "content": "Enterogenous cysts; report of case involving the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997802"}
{"pmid": "20997803", "title": "Liposarcoma of the mesentery.", "content": "Liposarcoma of the mesentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997803"}
{"pmid": "20997805", "title": "Surgical treatment for dysphagia lusoria.", "content": "Surgical treatment for dysphagia lusoria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997805"}
{"pmid": "20997804", "title": "Splenectomy; removal of a spleen weighing 5,450 grams.", "content": "Splenectomy; removal of a spleen weighing 5,450 grams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997804"}
{"pmid": "20997806", "title": "Pulmonary actinomycosis; its treatment by pulmonary resection in conjunction with chemotherapy.", "content": "Pulmonary actinomycosis; its treatment by pulmonary resection in conjunction with chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997806"}
{"pmid": "20997807", "title": "Management of injuries to Stensen's duct.", "content": "Management of injuries to Stensen's duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997807"}
{"pmid": "20997808", "title": "Mastectomy for gynecomastia through a semicircular intra-areolar incision.", "content": "Mastectomy for gynecomastia through a semicircular intra-areolar incision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997808"}
{"pmid": "20997809", "title": "Subtrochanteric osteotomy for ununited fracture neck of the femur.", "content": "Subtrochanteric osteotomy for ununited fracture neck of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997809"}
{"pmid": "20997810", "title": "Incisions in surgery of aneurysms; with special reference to exploration in the anticubital and popliteal fossae.", "content": "Incisions in surgery of aneurysms; with special reference to exploration in the anticubital and popliteal fossae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997810"}
{"pmid": "20997811", "title": "Cross nerve anastomosis in man.", "content": "Cross nerve anastomosis in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997811"}
{"pmid": "20997812", "title": "Foreign body in the colon.", "content": "Foreign body in the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997812"}
{"pmid": "20997813", "title": "Pathologic intervertebral disk and its consequences; a contribution to the cause and treatment of chronic pain low in the back and to the subject of herniating intervertebral disk.", "content": "Pathologic intervertebral disk and its consequences; a contribution to the cause and treatment of chronic pain low in the back and to the subject of herniating intervertebral disk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997813"}
{"pmid": "20997814", "title": "Acute superior mesenteric artery thrombosis; recovery following extensive resection of small and large intestines.", "content": "Acute superior mesenteric artery thrombosis; recovery following extensive resection of small and large intestines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997814"}
{"pmid": "20997815", "title": "Zephiran chloride for the preoperative preparation of the hands.", "content": "Zephiran chloride for the preoperative preparation of the hands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997815"}
{"pmid": "20997816", "title": "Repair of defects of the skull; with special reference to the periorbital structures and frontal sinus.", "content": "Repair of defects of the skull; with special reference to the periorbital structures and frontal sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997816"}
{"pmid": "20997817", "title": "Chemosurgical treatment of cancer of the nose; a microscopically controlled method.", "content": "Chemosurgical treatment of cancer of the nose; a microscopically controlled method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997817"}
{"pmid": "20997818", "title": "New method of leg exercises.", "content": "New method of leg exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997818"}
{"pmid": "20997820", "title": "Non-traumatic spontaneous rupture of the spleen.", "content": "Non-traumatic spontaneous rupture of the spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997820"}
{"pmid": "20997819", "title": "Reaction of tissue to and the fate of oxidized cellulose in the peritoneal cavity of the dog.", "content": "Reaction of tissue to and the fate of oxidized cellulose in the peritoneal cavity of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997819"}
{"pmid": "20997822", "title": "Omentovolvulus", "content": "Omentovolvulus", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997822"}
{"pmid": "20997845", "title": "An evaluation of sympathetic nerve interruption in a variety of surgical conditions.", "content": "An evaluation of sympathetic nerve interruption in a variety of surgical conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997845"}
{"pmid": "20997849", "title": "The early clinical and radiologic manifestations of small bowel obstruction.", "content": "The early clinical and radiologic manifestations of small bowel obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997849"}
{"pmid": "20997848", "title": "X-ray therapy an aid to surgery in conditions other than tumor.", "content": "X-ray therapy an aid to surgery in conditions other than tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997848"}
{"pmid": "20997846", "title": "The surgical treatment of bronchiectasis.", "content": "The surgical treatment of bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997846"}
{"pmid": "20997850", "title": "Prolapse of the rectum.", "content": "Prolapse of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997850"}
{"pmid": "20997847", "title": "Use of routine bed exercises following major surgery.", "content": "Use of routine bed exercises following major surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997847"}
{"pmid": "20997851", "title": "Recent developments in surgery.", "content": "Recent developments in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997851"}
{"pmid": "20997852", "title": "Indications for splenectomy.", "content": "Indications for splenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997852"}
{"pmid": "20997853", "title": "Parathyroid cyst.", "content": "Parathyroid cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997853"}
{"pmid": "20997854", "title": "The management of common duct stone missed at operation.", "content": "The management of common duct stone missed at operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997854"}
{"pmid": "20997855", "title": "Eclamptogenic toxemia.", "content": "Eclamptogenic toxemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997855"}
{"pmid": "20997856", "title": "Subtotal esophagectomy with high intrathoracic esophagogastric anastomosis in the treatment of extensive cicatricial obliteration of the esophagus.", "content": "Subtotal esophagectomy with high intrathoracic esophagogastric anastomosis in the treatment of extensive cicatricial obliteration of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997856"}
{"pmid": "20997857", "title": "Suppurative cholangitis complicating sidetracking operations of the biliary tract.", "content": "Suppurative cholangitis complicating sidetracking operations of the biliary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997857"}
{"pmid": "20997858", "title": "The surgical significance of aortic arch anomalies.", "content": "The surgical significance of aortic arch anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997858"}
{"pmid": "20997859", "title": "Thrombophlebitis of the deep veins in thromboangiitis obliterans.", "content": "Thrombophlebitis of the deep veins in thromboangiitis obliterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997859"}
{"pmid": "20997860", "title": "Relative surgical curability of certain gross types of gastric carcinoma.", "content": "Relative surgical curability of certain gross types of gastric carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997860"}
{"pmid": "20997861", "title": "Management of plastic maxillofacial wounds in an evacuation hospital.", "content": "Management of plastic maxillofacial wounds in an evacuation hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997861"}
{"pmid": "20997862", "title": "Transverse presentation.", "content": "Transverse presentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997862"}
{"pmid": "20997863", "title": "Gastric cancer; laparotomy, resectability, and mortality.", "content": "Gastric cancer; laparotomy, resectability, and mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997863"}
{"pmid": "20997864", "title": "Bilateral and multiple ruptured discs as one cause of persistent symptoms following operation for herniated disc.", "content": "Bilateral and multiple ruptured discs as one cause of persistent symptoms following operation for herniated disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997864"}
{"pmid": "20997865", "title": "Metastatic hypernephroma of the thyroid gland.", "content": "Metastatic hypernephroma of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997865"}
{"pmid": "20997866", "title": "Malformation of the anus and rectum.", "content": "Malformation of the anus and rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997866"}
{"pmid": "20997867", "title": "The management of osteomyelitis secondary to war wounds.", "content": "The management of osteomyelitis secondary to war wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997867"}
{"pmid": "20997868", "title": "The surgical treatment of gangrene in trench foot.", "content": "The surgical treatment of gangrene in trench foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997868"}
{"pmid": "20997869", "title": "A study of the absorption characteristics of surgical catgut.", "content": "A study of the absorption characteristics of surgical catgut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997869"}
{"pmid": "20997870", "title": "The effect of the anticoagulants on postpartum bleeding.", "content": "The effect of the anticoagulants on postpartum bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997870"}
{"pmid": "20997871", "title": "Talc granuloma.", "content": "Talc granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997871"}
{"pmid": "20997872", "title": "Section of the vagus nerves to the stomach in the treatment of peptic ulcer.", "content": "Section of the vagus nerves to the stomach in the treatment of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997872"}
{"pmid": "20997873", "title": "The treatment of hyperthyroidism with thiouracil, with particular reference to toxic reactions.", "content": "The treatment of hyperthyroidism with thiouracil, with particular reference to toxic reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997873"}
{"pmid": "20997874", "title": "Treatment of extremities following sudden failure of circulation.", "content": "Treatment of extremities following sudden failure of circulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997874"}
{"pmid": "20997875", "title": "Gangrene following fracture treated with heparin; papaverine, and intermittent venous occlusion; report of a case; reasons for using heparin.", "content": "Gangrene following fracture treated with heparin; papaverine, and intermittent venous occlusion; report of a case; reasons for using heparin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997875"}
{"pmid": "20997876", "title": "Hydronephrosis; the surgical treatment.", "content": "Hydronephrosis; the surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997876"}
{"pmid": "20997877", "title": "A method for the chemical production of a prolonged sympathetic paralysis; report of its use in two patients with causalgia.", "content": "A method for the chemical production of a prolonged sympathetic paralysis; report of its use in two patients with causalgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997877"}
{"pmid": "20997878", "title": "Tenon and mortise grafts for bridging metacarpal defects due to gunshot wounds.", "content": "Tenon and mortise grafts for bridging metacarpal defects due to gunshot wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997878"}
{"pmid": "20997879", "title": "Two unusual cases of war wounds of the heart.", "content": "Two unusual cases of war wounds of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997879"}
{"pmid": "20997880", "title": "The effect of atropine on the gastric secretion following thermal trauma.", "content": "The effect of atropine on the gastric secretion following thermal trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997880"}
{"pmid": "20997881", "title": "Bilateral popliteal hernia.", "content": "Bilateral popliteal hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997881"}
{"pmid": "20997882", "title": "Closure of the colostomy stoma, a simplified plan of management.", "content": "Closure of the colostomy stoma, a simplified plan of management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997882"}
{"pmid": "20997883", "title": "Experiments in ulcerative enteritis; failure to produce it by mesenteric lymphatic obstruction.", "content": "Experiments in ulcerative enteritis; failure to produce it by mesenteric lymphatic obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997883"}
{"pmid": "20997884", "title": "The split-thickness skin graft as a covering following removal of a fingernail.", "content": "The split-thickness skin graft as a covering following removal of a fingernail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997884"}
{"pmid": "20997885", "title": "Actinomycosis.", "content": "Actinomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997885"}
{"pmid": "20997886", "title": "Professional observations from Shanghai.", "content": "Professional observations from Shanghai.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997886"}
{"pmid": "20997887", "title": "Gastrojejunal ulcer following gastric resection.", "content": "Gastrojejunal ulcer following gastric resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997887"}
{"pmid": "20997888", "title": "Spinal anesthesia in vaginal deliveries.", "content": "Spinal anesthesia in vaginal deliveries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997888"}
{"pmid": "20997889", "title": "Transthoracic operation for megesophagus.", "content": "Transthoracic operation for megesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997889"}
{"pmid": "20997890", "title": "The current literature in obstetrics and gynecology; an informal analysis.", "content": "The current literature in obstetrics and gynecology; an informal analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997890"}
{"pmid": "20997891", "title": "Malignant adenoma of bronchus.", "content": "Malignant adenoma of bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997891"}
{"pmid": "20997892", "title": "ROLE of roentgen therapy in carcinoma of the breast.", "content": "ROLE of roentgen therapy in carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997892"}
{"pmid": "20997893", "title": "LIGATION of the inferior vena cava.", "content": "LIGATION of the inferior vena cava.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997893"}
{"pmid": "20997894", "title": "Taxonomy of the Ethiopian sandflies (Phlebotomus); keys for the identification of the Ethiopian species.", "content": "Taxonomy of the Ethiopian sandflies (Phlebotomus); keys for the identification of the Ethiopian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997894"}
{"pmid": "20997895", "title": "The experimental infection of rats with Entamoeba histolytica; with a method for evaluating the anti-amoebic properties of new compounds.", "content": "The experimental infection of rats with Entamoeba histolytica; with a method for evaluating the anti-amoebic properties of new compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997895"}
{"pmid": "20997896", "title": "Salivation by Glossina morsitans on to glass slides; a technique for isolating infected flies.", "content": "Salivation by Glossina morsitans on to glass slides; a technique for isolating infected flies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997896"}
{"pmid": "20997897", "title": "Studies on synthetic antimalarial drugs; the absorption, distribution and excretion of 2-p-chlorophenylguanidino-4 beta-diethylaminoethylamino-6-methylpyrimidine (3349) in experimental animals.", "content": "Studies on synthetic antimalarial drugs; the absorption, distribution and excretion of 2-p-chlorophenylguanidino-4 beta-diethylaminoethylamino-6-methylpyrimidine (3349) in experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997897"}
{"pmid": "20997898", "title": "Studies on synthetic antimalarial drugs; the absorption, distribution and excretion of N1-p-chlorophenyl-N5-methyl-N5-isopropylbiguanide (4430) in experimental animals and man.", "content": "Studies on synthetic antimalarial drugs; the absorption, distribution and excretion of N1-p-chlorophenyl-N5-methyl-N5-isopropylbiguanide (4430) in experimental animals and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997898"}
{"pmid": "20997899", "title": "Some notes on the maintenance and breeding of schistosome vectors in Great Britain, with special reference to Planorbis guadaloupensis Sowerby.", "content": "Some notes on the maintenance and breeding of schistosome vectors in Great Britain, with special reference to Planorbis guadaloupensis Sowerby.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997899"}
{"pmid": "20997900", "title": "A further note on the nomenclature and identity of the frog filaria Foleyella leiperi (Railliet, 1916).", "content": "A further note on the nomenclature and identity of the frog filaria Foleyella leiperi (Railliet, 1916).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997900"}
{"pmid": "20997901", "title": "Mepacrine in animal tissues.", "content": "Mepacrine in animal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997901"}
{"pmid": "20997903", "title": "Suppression of benign tertian malaria with mepacrine; an investigation of 247 cases of apparent failure.", "content": "Suppression of benign tertian malaria with mepacrine; an investigation of 247 cases of apparent failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997903"}
{"pmid": "20997902", "title": "Distribution of mepacrine in blood.", "content": "Distribution of mepacrine in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997902"}
{"pmid": "20997904", "title": "Carbohydrate metabolism in bovine trypanosomiasis.", "content": "Carbohydrate metabolism in bovine trypanosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997904"}
{"pmid": "20997905", "title": "An apparatus for collecting blood-sucking mites.", "content": "An apparatus for collecting blood-sucking mites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997905"}
{"pmid": "20997906", "title": "Prolonged oral administration of mepacrine; the clinical effects in women.", "content": "Prolonged oral administration of mepacrine; the clinical effects in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997906"}
{"pmid": "20997907", "title": "The maintenance of a colony of Phlebotomus papatasii in Great Britain.", "content": "The maintenance of a colony of Phlebotomus papatasii in Great Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997907"}
{"pmid": "20997908", "title": "The biology and maintenance of Liponyssus bacoti Hirst, 1913, and an investigation into its role as a vector of Litomosoides carinii to cotton rats and white rats, together with some observations on the infection in the white rats.", "content": "The biology and maintenance of Liponyssus bacoti Hirst, 1913, and an investigation into its role as a vector of Litomosoides carinii to cotton rats and white rats, together with some observations on the infection in the white rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997908"}
{"pmid": "20997909", "title": "Interference with the trypanocidal action of gamma-(p-arsenosophenyl) butyric acid by p-aminobenzoic acid.", "content": "Interference with the trypanocidal action of gamma-(p-arsenosophenyl) butyric acid by p-aminobenzoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997909"}
{"pmid": "20997910", "title": "BRONCHIAL asthma.", "content": "BRONCHIAL asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997910"}
{"pmid": "20997911", "title": "Symposium on infectious asthma.", "content": "Symposium on infectious asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997911"}
{"pmid": "20997912", "title": "Surgical management of infectious asthma.", "content": "Surgical management of infectious asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997912"}
{"pmid": "20997913", "title": "Use of oral penicillin in treatment of bacterial asthma.", "content": "Use of oral penicillin in treatment of bacterial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997913"}
{"pmid": "20997914", "title": "Chronic toxicity of N'pyridyl, N'benzyl, dimethyl-ethylenediamine monohydrochloride (pyribenzamine).", "content": "Chronic toxicity of N'pyridyl, N'benzyl, dimethyl-ethylenediamine monohydrochloride (pyribenzamine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997914"}
{"pmid": "20997915", "title": "Clinical studies with N'pyridyl, N'benzyl, dimethyl-ethylenediamine monohydrochloride (pyribenzamine).", "content": "Clinical studies with N'pyridyl, N'benzyl, dimethyl-ethylenediamine monohydrochloride (pyribenzamine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997915"}
{"pmid": "20997916", "title": "Studies to determine the ability of tyrothricin to sensitize the skin.", "content": "Studies to determine the ability of tyrothricin to sensitize the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997916"}
{"pmid": "20997917", "title": "A report of the clinical studies on the use of pyribenzamine in allergic diseases by the Committee on Pharmaceuticals and Medicaments of the American Academy of Allergy.", "content": "A report of the clinical studies on the use of pyribenzamine in allergic diseases by the Committee on Pharmaceuticals and Medicaments of the American Academy of Allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997917"}
{"pmid": "20997919", "title": "Pulmonary complications following regional analgesia for abdominal operations.", "content": "Pulmonary complications following regional analgesia for abdominal operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997919"}
{"pmid": "20997918", "title": "Experiments in electrical anaesthesia and barbiturate basal narcosis.", "content": "Experiments in electrical anaesthesia and barbiturate basal narcosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997918"}
{"pmid": "20997920", "title": "The management of subarachnoid analgesia by the continuous drop method.", "content": "The management of subarachnoid analgesia by the continuous drop method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997920"}
{"pmid": "20997921", "title": "The future of research in aviation medicine.", "content": "The future of research in aviation medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997921"}
{"pmid": "20997922", "title": "Studies on positive pressure respiration; general aspects and types of pressure breathing; effects on respiration and circulation at sea level.", "content": "Studies on positive pressure respiration; general aspects and types of pressure breathing; effects on respiration and circulation at sea level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997922"}
{"pmid": "20997923", "title": "Civilian aviation and medical education.", "content": "Civilian aviation and medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997923"}
{"pmid": "20997924", "title": "Studies on altitude decompression sickness; symptomatology.", "content": "Studies on altitude decompression sickness; symptomatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997924"}
{"pmid": "20997925", "title": "The effectiveness of some motion sickness remedies in preventing air sickness in Air Force Navigation students.", "content": "The effectiveness of some motion sickness remedies in preventing air sickness in Air Force Navigation students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997925"}
{"pmid": "20997926", "title": "Use of hyoscine hydrobromide for the prevention of airsickness in flexible gunnery students.", "content": "Use of hyoscine hydrobromide for the prevention of airsickness in flexible gunnery students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997926"}
{"pmid": "20997927", "title": "A device for demonstrating the effects of anoxia on vision.", "content": "A device for demonstrating the effects of anoxia on vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997927"}
{"pmid": "20997928", "title": "Effect of pressure breathing on circulation at high altitude as measured by the ballistocardiograph.", "content": "Effect of pressure breathing on circulation at high altitude as measured by the ballistocardiograph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997928"}
{"pmid": "20997929", "title": "An automatic rip cord for high altitude bail-out.", "content": "An automatic rip cord for high altitude bail-out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997929"}
{"pmid": "20997930", "title": "The nature and distribution of various forms of nitrogen in the potato.", "content": "The nature and distribution of various forms of nitrogen in the potato.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997930"}
{"pmid": "20997931", "title": "Some causes of chlorosis and necrosis of sugar-beet foliage.", "content": "Some causes of chlorosis and necrosis of sugar-beet foliage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997931"}
{"pmid": "20997932", "title": "Verticillium wilt of sainfoin.", "content": "Verticillium wilt of sainfoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997932"}
{"pmid": "20997933", "title": "Eyespot of wheat and barley in Scotland in 1944.", "content": "Eyespot of wheat and barley in Scotland in 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997933"}
{"pmid": "20997934", "title": "The control of narcissus leaf diseases; Sclerotinia polyblastis Greg. on Narcissus tazetta var. Soleil d'Or.", "content": "The control of narcissus leaf diseases; Sclerotinia polyblastis Greg. on Narcissus tazetta var. Soleil d'Or.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997934"}
{"pmid": "20997935", "title": "Varietal differences in susceptibility to potato virus Y.", "content": "Varietal differences in susceptibility to potato virus Y.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997935"}
{"pmid": "20997938", "title": "The cereals root eelworm, Heterodera major (O. Schmidt) Franklin, in North Wales.", "content": "The cereals root eelworm, Heterodera major (O. Schmidt) Franklin, in North Wales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997938"}
{"pmid": "20997937", "title": "Field trials of copper fungicides for the control of potato blight; spray retention.", "content": "Field trials of copper fungicides for the control of potato blight; spray retention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997937"}
{"pmid": "20997936", "title": "Resolution of strawberry virus complexes by means of the aphis vector Capitophorus fragariae Theob.", "content": "Resolution of strawberry virus complexes by means of the aphis vector Capitophorus fragariae Theob.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997936"}
{"pmid": "20997941", "title": "A study of the distribution of the swede smudge Contarinia nasturtii Kieffer in Devon and symptoms of its attack on various host plants.", "content": "A study of the distribution of the swede smudge Contarinia nasturtii Kieffer in Devon and symptoms of its attack on various host plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997941"}
{"pmid": "20997939", "title": "The shallot aphis, Myzus ascalonicus Doncaster, and its behaviour as a vector of plant viruses.", "content": "The shallot aphis, Myzus ascalonicus Doncaster, and its behaviour as a vector of plant viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997939"}
{"pmid": "20997940", "title": "Bionomics of the carrot fly Psila rosae F.; the infestation and sampling of carrot crops.", "content": "Bionomics of the carrot fly Psila rosae F.; the infestation and sampling of carrot crops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997940"}
{"pmid": "20997942", "title": "Tyroglyphid mites in stored products; ecological studies.", "content": "Tyroglyphid mites in stored products; ecological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997942"}
{"pmid": "20997945", "title": "A method of estimating the numbers of soil protozoa, especially amoebae, based on their differential feeding on bacteria.", "content": "A method of estimating the numbers of soil protozoa, especially amoebae, based on their differential feeding on bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997945"}
{"pmid": "20997946", "title": "RECRUITMENT and training of plant pathologists in Great Britain.", "content": "RECRUITMENT and training of plant pathologists in Great Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997946"}
{"pmid": "20997944", "title": "Toxicity to rainbow trout and minnows of some substances known to be present in waste water discharged to rivers.", "content": "Toxicity to rainbow trout and minnows of some substances known to be present in waste water discharged to rivers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997944"}
{"pmid": "20997943", "title": "The toxicity of certain aliphatic chlorinated hydrocarbons to Calandra granaria L. and other insects infesting grain.", "content": "The toxicity of certain aliphatic chlorinated hydrocarbons to Calandra granaria L. and other insects infesting grain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997943"}
{"pmid": "20997948", "title": "Experiments with D.D.T. smokes.", "content": "Experiments with D.D.T. smokes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997948"}
{"pmid": "20997947", "title": "Apple blossom weevil and its control by D. D. T.", "content": "Apple blossom weevil and its control by D. D. T.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997947"}
{"pmid": "20997949", "title": "The control of flies in farm buildings by D. D. T.", "content": "The control of flies in farm buildings by D. D. T.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997949"}
{"pmid": "20997951", "title": "The quantity and distribution of spray collected by insects flying through insecticidal mists.", "content": "The quantity and distribution of spray collected by insects flying through insecticidal mists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997951"}
{"pmid": "20997950", "title": "The control of sheep blowflies by D. D. T. dips.", "content": "The control of sheep blowflies by D. D. T. dips.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997950"}
{"pmid": "20997952", "title": "Effects of atmospheric environment, before and after treatment, on the toxicity to insects of contact poisons.", "content": "Effects of atmospheric environment, before and after treatment, on the toxicity to insects of contact poisons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997952"}
{"pmid": "20997953", "title": "The analysis of a factorial series of insecticide tests.", "content": "The analysis of a factorial series of insecticide tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997953"}
{"pmid": "20997954", "title": "Note on the effect of wireworms of the genera Agriotes and Corymbites on crop yields.", "content": "Note on the effect of wireworms of the genera Agriotes and Corymbites on crop yields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997954"}
{"pmid": "20997955", "title": "Simple laboratory and field apparatus for the production of accurate line drawings to scale.", "content": "Simple laboratory and field apparatus for the production of accurate line drawings to scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997955"}
{"pmid": "20997956", "title": "A note on results from spectrographic analysis of coffee material.", "content": "A note on results from spectrographic analysis of coffee material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997956"}
{"pmid": "20997957", "title": "The ecology of the larger fungi; an investigation into the influence of rainfall and temperature on the seasonal production of fungi in a beechwood and a pinewood.", "content": "The ecology of the larger fungi; an investigation into the influence of rainfall and temperature on the seasonal production of fungi in a beechwood and a pinewood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997957"}
{"pmid": "20997958", "title": "Investigation into the production of bacteriostatic substances by fungi; preliminary examination of more of the larger Basidiomycetes and some of the larger Ascomycetes.", "content": "Investigation into the production of bacteriostatic substances by fungi; preliminary examination of more of the larger Basidiomycetes and some of the larger Ascomycetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997958"}
{"pmid": "20997960", "title": "Diseases of the gladiolus; Botrytis rot of corms and its control.", "content": "Diseases of the gladiolus; Botrytis rot of corms and its control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997960"}
{"pmid": "20997961", "title": "Diseases of the gladiolus; note on the incidence and control of scab disease Bacterium marginatum McCull.", "content": "Diseases of the gladiolus; note on the incidence and control of scab disease Bacterium marginatum McCull.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997961"}
{"pmid": "20997959", "title": "The production of viridin by pigment-forming strains of Trichoderma viride.", "content": "The production of viridin by pigment-forming strains of Trichoderma viride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997959"}
{"pmid": "20997962", "title": "Further studies on the effect of disinfecting and bruising seed potatoes on the incidence of dry rot Fusarium caeruleum (Lib.) Sacc.", "content": "Further studies on the effect of disinfecting and bruising seed potatoes on the incidence of dry rot Fusarium caeruleum (Lib.) Sacc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997962"}
{"pmid": "20997963", "title": "Dry rot of potato Fusarium caeruleum (Lib.) Sacc.; effect of planting infected and contaminated sets on plant establishment.", "content": "Dry rot of potato Fusarium caeruleum (Lib.) Sacc.; effect of planting infected and contaminated sets on plant establishment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997963"}
{"pmid": "20997964", "title": "Seed-borne diseases.", "content": "Seed-borne diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997964"}
{"pmid": "20997965", "title": "A scheme for the official approval of proprietary insecticides and fungicides.", "content": "A scheme for the official approval of proprietary insecticides and fungicides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997965"}
{"pmid": "20997971", "title": "The microflora of the alimentary canal.", "content": "The microflora of the alimentary canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997971"}
{"pmid": "20997973", "title": "The problem of chromosome re-arrangements in somatic cells of Drosophila melanogaster.", "content": "The problem of chromosome re-arrangements in somatic cells of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997973"}
{"pmid": "20997972", "title": "Ectopic pairing and the distribution of heterochromatin in the X-chromosome of salivary gland nuclei of Drosophila melanogaster.", "content": "Ectopic pairing and the distribution of heterochromatin in the X-chromosome of salivary gland nuclei of Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997972"}
{"pmid": "20997975", "title": "Histochemical studies of keratin fibres.", "content": "Histochemical studies of keratin fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997975"}
{"pmid": "20997974", "title": "Quantitative evolution; the diatoms.", "content": "Quantitative evolution; the diatoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997974"}
{"pmid": "20997976", "title": "A comparative study of the cytoplasmic components of the male germ-cells of certain mammals.", "content": "A comparative study of the cytoplasmic components of the male germ-cells of certain mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997976"}
{"pmid": "20997977", "title": "Inheritance of resistance to blight (Phytophthora infestans) in potatoes; unbalanced segregations.", "content": "Inheritance of resistance to blight (Phytophthora infestans) in potatoes; unbalanced segregations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997977"}
{"pmid": "20997978", "title": "Degenerative and regenerative changes at the site of trauma after experimental crush injury of peripheral nerves.", "content": "Degenerative and regenerative changes at the site of trauma after experimental crush injury of peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997978"}
{"pmid": "20997979", "title": "Placental fusion in mice.", "content": "Placental fusion in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997979"}
{"pmid": "20997980", "title": "Infertility and embryonic mortality in the domestic fowl.", "content": "Infertility and embryonic mortality in the domestic fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997980"}
{"pmid": "20997981", "title": "The use of rats for pressor assays of pituitary extracts, with a note on response to histamine and adrenaline.", "content": "The use of rats for pressor assays of pituitary extracts, with a note on response to histamine and adrenaline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997981"}
{"pmid": "20997982", "title": "Chemically induced mosaicism in Drosophila melanogaster.", "content": "Chemically induced mosaicism in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997982"}
{"pmid": "20997983", "title": "Situs inversus viscerum in a white rat (Mus norvegicus).", "content": "Situs inversus viscerum in a white rat (Mus norvegicus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997983"}
{"pmid": "20997984", "title": "Rate of gain of heat-tolerance in goldfish (Carassius auratus).", "content": "Rate of gain of heat-tolerance in goldfish (Carassius auratus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997984"}
{"pmid": "20997985", "title": "Parasites of fish of Algonquin Park lakes.", "content": "Parasites of fish of Algonquin Park lakes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997985"}
{"pmid": "20997986", "title": "LARYNGOSCOPE bronchoscope, and esophagoscope as aids in the early diagnosis of cancer.", "content": "LARYNGOSCOPE bronchoscope, and esophagoscope as aids in the early diagnosis of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997986"}
{"pmid": "20997999", "title": "Adenosine deaminase from Aspergillus oryzae.", "content": "Adenosine deaminase from Aspergillus oryzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997999"}
{"pmid": "20997998", "title": "A spectrophotometric measurement of adenosine deamination.", "content": "A spectrophotometric measurement of adenosine deamination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20997998"}
{"pmid": "20998000", "title": "The amino acid composition of cow and human milk proteins.", "content": "The amino acid composition of cow and human milk proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998000"}
{"pmid": "20998001", "title": "Some factors affecting the production of itaconic acid by Aspergillus terreus in agitated cultures.", "content": "Some factors affecting the production of itaconic acid by Aspergillus terreus in agitated cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998001"}
{"pmid": "20998002", "title": "The influence of ascorbic acid on the anaerobic respiration of sweet-potato slices.", "content": "The influence of ascorbic acid on the anaerobic respiration of sweet-potato slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998002"}
{"pmid": "20998003", "title": "Reversal of sodium propionate inhibition of Escherichia coli with beta-alanine.", "content": "Reversal of sodium propionate inhibition of Escherichia coli with beta-alanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998003"}
{"pmid": "20998004", "title": "The effect of the level of casein, cystine and methionine intake on riboflavin retention and protein utilization by the rat.", "content": "The effect of the level of casein, cystine and methionine intake on riboflavin retention and protein utilization by the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998004"}
{"pmid": "20998005", "title": "The biochemistry of the malaria parasite; in vitro studies on the distribution of quinine between blood cells and their suspending medium.", "content": "The biochemistry of the malaria parasite; in vitro studies on the distribution of quinine between blood cells and their suspending medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998005"}
{"pmid": "20998006", "title": "The ultraviolet absorption of the plasma proteins.", "content": "The ultraviolet absorption of the plasma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998006"}
{"pmid": "20998007", "title": "Note on the use of hydrogen peroxide-treated peptone in media for the microbiological determination of amino acids.", "content": "Note on the use of hydrogen peroxide-treated peptone in media for the microbiological determination of amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998007"}
{"pmid": "20998008", "title": "Nutrition of rainbow trout; studies with purified rations.", "content": "Nutrition of rainbow trout; studies with purified rations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998008"}
{"pmid": "20998009", "title": "Enzymatic oxidation of glutathione; studies on the addition of several cofactors.", "content": "Enzymatic oxidation of glutathione; studies on the addition of several cofactors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998009"}
{"pmid": "20998010", "title": "Glutamic acid decarboxylase of higher plants; distribution; preparation of clear solutions; nature of prosthetic group.", "content": "Glutamic acid decarboxylase of higher plants; distribution; preparation of clear solutions; nature of prosthetic group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998010"}
{"pmid": "20998011", "title": "Physical and chemical studies on Southern bean mosaic virus; size, shape, hydration and elementary composition.", "content": "Physical and chemical studies on Southern bean mosaic virus; size, shape, hydration and elementary composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998011"}
{"pmid": "20998012", "title": "Pectic enzymes; the preparation of tomato pectin-methylesterase.", "content": "Pectic enzymes; the preparation of tomato pectin-methylesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998012"}
{"pmid": "20998013", "title": "Effect of bulk, casein and fat in the ration on the utilization of carotenes by white rats.", "content": "Effect of bulk, casein and fat in the ration on the utilization of carotenes by white rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998013"}
{"pmid": "20998014", "title": "Stereochemical configuration and provitamin A activity; neocryptoxanthin A.", "content": "Stereochemical configuration and provitamin A activity; neocryptoxanthin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998014"}
{"pmid": "20998015", "title": "Enzymatic mechanisms in the respiration of spinach leaves.", "content": "Enzymatic mechanisms in the respiration of spinach leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998015"}
{"pmid": "20998016", "title": "Spectrophotometric studies of the oxidation of fats; oxygen absorption and chromophore production in lipoxidase-oxidized fatty esters.", "content": "Spectrophotometric studies of the oxidation of fats; oxygen absorption and chromophore production in lipoxidase-oxidized fatty esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998016"}
{"pmid": "20998017", "title": "The inhibiting effect of thiourea and its derivatives, and of sulfur-containing amino acids on the formation of iodocasein.", "content": "The inhibiting effect of thiourea and its derivatives, and of sulfur-containing amino acids on the formation of iodocasein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998017"}
{"pmid": "20998018", "title": "Carotenes of Lycopersicon species and strains.", "content": "Carotenes of Lycopersicon species and strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998018"}
{"pmid": "20998019", "title": "Naturally occurring colorless polyenes.", "content": "Naturally occurring colorless polyenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998019"}
{"pmid": "20998020", "title": "Isolation of a new lipoprotein, lipovitellenin, from egg yolk.", "content": "Isolation of a new lipoprotein, lipovitellenin, from egg yolk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998020"}
{"pmid": "20998021", "title": "Identification of the bacteria-inhibiting iron-binding protein of egg white as conalbumin.", "content": "Identification of the bacteria-inhibiting iron-binding protein of egg white as conalbumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998021"}
{"pmid": "20998022", "title": "Hydrolysis of soybean oil meal proteins by some proteolytic enzymes.", "content": "Hydrolysis of soybean oil meal proteins by some proteolytic enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998022"}
{"pmid": "20998023", "title": "The mechanism of the antibacterial action of quinones and hydroquinones.", "content": "The mechanism of the antibacterial action of quinones and hydroquinones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998023"}
{"pmid": "20998024", "title": "Further studies on in vivo tooth decalcification by acid beverages.", "content": "Further studies on in vivo tooth decalcification by acid beverages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998024"}
{"pmid": "20998025", "title": "Studies on thymonucleodepolymerase.", "content": "Studies on thymonucleodepolymerase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998025"}
{"pmid": "20998026", "title": "The production of riboflavin by Mycobacterium smegmatis.", "content": "The production of riboflavin by Mycobacterium smegmatis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998026"}
{"pmid": "20998027", "title": "Studies in histochemistry; localization of phosphatases in the wheat grain and in the epicotyl and roots of the germinated grain.", "content": "Studies in histochemistry; localization of phosphatases in the wheat grain and in the epicotyl and roots of the germinated grain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998027"}
{"pmid": "20998028", "title": "Studies in histochemistry; localization of arginine in the wheat grain and in the epicotyl and roots of the germinated grain.", "content": "Studies in histochemistry; localization of arginine in the wheat grain and in the epicotyl and roots of the germinated grain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998028"}
{"pmid": "20998029", "title": "Investigations of amino acids, peptides and proteins; the histidine content of casein.", "content": "Investigations of amino acids, peptides and proteins; the histidine content of casein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998029"}
{"pmid": "20998030", "title": "The excretion of B-complex vitamins by normal adults on a restricted intake.", "content": "The excretion of B-complex vitamins by normal adults on a restricted intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998030"}
{"pmid": "20998031", "title": "Note on the ability of rat liver slices to perform certain reactions after different times of incubation.", "content": "Note on the ability of rat liver slices to perform certain reactions after different times of incubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998031"}
{"pmid": "20998032", "title": "Production of citric acid from cane molasses.", "content": "Production of citric acid from cane molasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998032"}
{"pmid": "20998033", "title": "Effect of metallic ions on the production of citric acid by Aspergillus niger.", "content": "Effect of metallic ions on the production of citric acid by Aspergillus niger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998033"}
{"pmid": "20998034", "title": "Lipolytic activities of anaerobic bacteria.", "content": "Lipolytic activities of anaerobic bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998034"}
{"pmid": "20998035", "title": "Glutamic acid decarboxylase of higher plants; pH-activity curve, reaction kinetics, inhibition by hydroxylamine.", "content": "Glutamic acid decarboxylase of higher plants; pH-activity curve, reaction kinetics, inhibition by hydroxylamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998035"}
{"pmid": "20998036", "title": "The comparative effect of the fatty acids of butterfat and corn oil on the growth and metabolism of microorganisms.", "content": "The comparative effect of the fatty acids of butterfat and corn oil on the growth and metabolism of microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998036"}
{"pmid": "20998037", "title": "Thermal destruction of influenza. A virus hemagglutinin; the effect of urea.", "content": "Thermal destruction of influenza. A virus hemagglutinin; the effect of urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998037"}
{"pmid": "20998038", "title": "Thermal destruction of influenza A virus hemagglutinin; the effect of initial virus concentration.", "content": "Thermal destruction of influenza A virus hemagglutinin; the effect of initial virus concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998038"}
{"pmid": "20998039", "title": "Molecular weight by solubility measurements.", "content": "Molecular weight by solubility measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998039"}
{"pmid": "20998040", "title": "Secondary radiation from x-ray filters; the design of efficient multimetal filters.", "content": "Secondary radiation from x-ray filters; the design of efficient multimetal filters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998040"}
{"pmid": "20998041", "title": "alpha-Cyano-beta-phenylglyceric acid.", "content": "alpha-Cyano-beta-phenylglyceric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998041"}
{"pmid": "20998042", "title": "The pore structure and adsorptive properties of some activated charcoals.", "content": "The pore structure and adsorptive properties of some activated charcoals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998042"}
{"pmid": "20998043", "title": "The pore structure and adsorptive properties of some activated charcoals; the apparent density of charcoal in liquid media.", "content": "The pore structure and adsorptive properties of some activated charcoals; the apparent density of charcoal in liquid media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998043"}
{"pmid": "20998044", "title": "The pore structure and adsorptive properties of some activated charcoals; the apparent density of water adsorbed on active charcoal.", "content": "The pore structure and adsorptive properties of some activated charcoals; the apparent density of water adsorbed on active charcoal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998044"}
{"pmid": "20998045", "title": "The influence of membrane preparation on the osmotic pressure of polyvinyl acetate in acetone.", "content": "The influence of membrane preparation on the osmotic pressure of polyvinyl acetate in acetone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998045"}
{"pmid": "20998046", "title": "The flow of gases and vapours through porus media.", "content": "The flow of gases and vapours through porus media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998046"}
{"pmid": "20998047", "title": "Chlorination by aqueous sodium hypochlorite.", "content": "Chlorination by aqueous sodium hypochlorite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998047"}
{"pmid": "20998048", "title": "The fatty acids of hare's-ear mustard seed oil.", "content": "The fatty acids of hare's-ear mustard seed oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998048"}
{"pmid": "20998049", "title": "Studies on reactions relating to carbohydrates and polysaccharides; stabilizing action of ethanol on starch nitrates.", "content": "Studies on reactions relating to carbohydrates and polysaccharides; stabilizing action of ethanol on starch nitrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998049"}
{"pmid": "20998050", "title": "Studies on reactions relating to carbohydrates and polysaccharides; properties of the fractionated nitrates of two fractions of corn starch.", "content": "Studies on reactions relating to carbohydrates and polysaccharides; properties of the fractionated nitrates of two fractions of corn starch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998050"}
{"pmid": "20998089", "title": "The in vitro rate of acid production from saliva-carbohydrate mixtures.", "content": "The in vitro rate of acid production from saliva-carbohydrate mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998089"}
{"pmid": "20998090", "title": "Increasing dental man-power; some factors relating to educational development to meet this problem.", "content": "Increasing dental man-power; some factors relating to educational development to meet this problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998090"}
{"pmid": "20998091", "title": "A case of Costen's syndrome.", "content": "A case of Costen's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998091"}
{"pmid": "20998084", "title": "New drugs and treatments evolved during the war.", "content": "New drugs and treatments evolved during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998084"}
{"pmid": "20998092", "title": "The relations between orthodontics and general dental practice.", "content": "The relations between orthodontics and general dental practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998092"}
{"pmid": "20998093", "title": "Some observations on trismus in relation to maxillo-facial surgery.", "content": "Some observations on trismus in relation to maxillo-facial surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998093"}
{"pmid": "20998081", "title": "The role of teeth with exposed pulps in the aetiology of anterior poliomyelitis.", "content": "The role of teeth with exposed pulps in the aetiology of anterior poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998081"}
{"pmid": "20998082", "title": "Radiograms and their interpretation.", "content": "Radiograms and their interpretation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998082"}
{"pmid": "20998083", "title": "Surgical principles and technique in the removal of retained roots, cysts, etc.", "content": "Surgical principles and technique in the removal of retained roots, cysts, etc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998083"}
{"pmid": "20998085", "title": "Pedodontia.", "content": "Pedodontia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998085"}
{"pmid": "20998094", "title": "Absence of premolars.", "content": "Absence of premolars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998094"}
{"pmid": "20998086", "title": "Retained tooth roots.", "content": "Retained tooth roots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998086"}
{"pmid": "20998087", "title": "Chemotherapy.", "content": "Chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998087"}
{"pmid": "20998088", "title": "Local anodontia.", "content": "Local anodontia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998088"}
{"pmid": "20998098", "title": "Accurate bite registration and the adaptable articulator; fundamentals of full denture construction.", "content": "Accurate bite registration and the adaptable articulator; fundamentals of full denture construction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998098"}
{"pmid": "20998099", "title": "The camera in dentistry; its use in building a visual education file.", "content": "The camera in dentistry; its use in building a visual education file.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998099"}
{"pmid": "20998102", "title": "The application of drug therapy in dental practice.", "content": "The application of drug therapy in dental practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998102"}
{"pmid": "20998100", "title": "Practical psychology in dentistry for children; a prime essential for success.", "content": "Practical psychology in dentistry for children; a prime essential for success.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998100"}
{"pmid": "20998101", "title": "Problems in doing dental work for children.", "content": "Problems in doing dental work for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998101"}
{"pmid": "20998105", "title": "Nutrition and the child.", "content": "Nutrition and the child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998105"}
{"pmid": "20998104", "title": "Some aspects of caries pathology and their clinical application.", "content": "Some aspects of caries pathology and their clinical application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998104"}
{"pmid": "20998106", "title": "Women in dentistry.", "content": "Women in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998106"}
{"pmid": "20998108", "title": "The nutritional and systemic background in some cases of periodontoclasia.", "content": "The nutritional and systemic background in some cases of periodontoclasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998108"}
{"pmid": "20998095", "title": "Pericoronitis; a review of the literature.", "content": "Pericoronitis; a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998095"}
{"pmid": "20998110", "title": "NEW home of Temple University School of Dentistry.", "content": "NEW home of Temple University School of Dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998110"}
{"pmid": "20998109", "title": "The dental hygienist's part in a health program.", "content": "The dental hygienist's part in a health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998109"}
{"pmid": "20998107", "title": "Atomic versus molecular oxygen.", "content": "Atomic versus molecular oxygen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998107"}
{"pmid": "20998111", "title": "LABILE methyl groups in nutrition; new findings.", "content": "LABILE methyl groups in nutrition; new findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998111"}
{"pmid": "20998112", "title": "Australia's agar industry.", "content": "Australia's agar industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998112"}
{"pmid": "20998096", "title": "Caries etiology in the past; a historical review.", "content": "Caries etiology in the past; a historical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998096"}
{"pmid": "20998113", "title": "The dietitian's program for food service modernization.", "content": "The dietitian's program for food service modernization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998113"}
{"pmid": "20998097", "title": "The movement for health insurance; a discussion of various health plans throughout the world.", "content": "The movement for health insurance; a discussion of various health plans throughout the world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998097"}
{"pmid": "20998114", "title": "Thiamin content of typical general and soft hospital diets.", "content": "Thiamin content of typical general and soft hospital diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998114"}
{"pmid": "20998115", "title": "Nutritional status of women students.", "content": "Nutritional status of women students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998115"}
{"pmid": "20998117", "title": "The change in thiamin content of breakfast cereals during cooking.", "content": "The change in thiamin content of breakfast cereals during cooking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998117"}
{"pmid": "20998116", "title": "Dietary requirements for fertility and lactation; brewers' and cultured food yeasts as sources of proteins and the vitamin B complex for growth, reproduction and lactation.", "content": "Dietary requirements for fertility and lactation; brewers' and cultured food yeasts as sources of proteins and the vitamin B complex for growth, reproduction and lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998116"}
{"pmid": "20998118", "title": "The vitamin content of canned and cooked fresh mushrooms.", "content": "The vitamin content of canned and cooked fresh mushrooms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998118"}
{"pmid": "20998119", "title": "Body adaptation to change in diet.", "content": "Body adaptation to change in diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998119"}
{"pmid": "20998120", "title": "Weight reduction of obese women of college age; clinical results and basal metabolism.", "content": "Weight reduction of obese women of college age; clinical results and basal metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998120"}
{"pmid": "20998121", "title": "Weight reduction of obese women of college age; nitrogen, calcium, and phosphorus retentions of young women during weight reduction.", "content": "Weight reduction of obese women of college age; nitrogen, calcium, and phosphorus retentions of young women during weight reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998121"}
{"pmid": "20998123", "title": "Prewar nutrition in rural China.", "content": "Prewar nutrition in rural China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998123"}
{"pmid": "20998122", "title": "Sodium restriction as a dietary measure in hypertension.", "content": "Sodium restriction as a dietary measure in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998122"}
{"pmid": "20998124", "title": "Sanitation for food departments.", "content": "Sanitation for food departments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998124"}
{"pmid": "20998125", "title": "Distribution of calcium in various parts of endive and celery.", "content": "Distribution of calcium in various parts of endive and celery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998125"}
{"pmid": "20998126", "title": "The retention of thiamin and riboflavin in beef cuts during braising, frying, and broiling.", "content": "The retention of thiamin and riboflavin in beef cuts during braising, frying, and broiling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998126"}
{"pmid": "20998127", "title": "Garnering edible mushrooms for vitamins and minerals.", "content": "Garnering edible mushrooms for vitamins and minerals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998127"}
{"pmid": "20998128", "title": "Population trends in Palestine.", "content": "Population trends in Palestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998128"}
{"pmid": "20998129", "title": "Education for family life.", "content": "Education for family life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998129"}
{"pmid": "20998130", "title": "Positive eugenics; a proposal.", "content": "Positive eugenics; a proposal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998130"}
{"pmid": "20998131", "title": "Assortative mating.", "content": "Assortative mating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998131"}
{"pmid": "20998132", "title": "Is Britain overpopulated?", "content": "Is Britain overpopulated?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998132"}
{"pmid": "20998134", "title": "Modification of the frequency of chromosomal rearrangements induced by x-rays in Drosophila; effect of supplementary treatment at the time of chromosome recombination.", "content": "Modification of the frequency of chromosomal rearrangements induced by x-rays in Drosophila; effect of supplementary treatment at the time of chromosome recombination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998134"}
{"pmid": "20998135", "title": "On the effects of the gene alpha on the chemical composition of Ephestia künniella Zeller.", "content": "On the effects of the gene alpha on the chemical composition of Ephestia künniella Zeller.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998135"}
{"pmid": "20998136", "title": "Cytological studies in the Musae; meiosis in some diploid clones.", "content": "Cytological studies in the Musae; meiosis in some diploid clones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998136"}
{"pmid": "20998137", "title": "Cytological studies in the Musae; meiosis in some seedling clones.", "content": "Cytological studies in the Musae; meiosis in some seedling clones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998137"}
{"pmid": "20998138", "title": "Genetic and nongenetic sources of variation in the weight response of the immature rat ovary to a gonadotrophic hormone.", "content": "Genetic and nongenetic sources of variation in the weight response of the immature rat ovary to a gonadotrophic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998138"}
{"pmid": "20998139", "title": "Chromosome variation in Drosophila athabasca.", "content": "Chromosome variation in Drosophila athabasca.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998139"}
{"pmid": "20998140", "title": "Genetical studies on the chlorophyll apparatus in oats and wheat.", "content": "Genetical studies on the chlorophyll apparatus in oats and wheat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998140"}
{"pmid": "20998141", "title": "Influence of temperature on the nucleolus and its coacervate nature.", "content": "Influence of temperature on the nucleolus and its coacervate nature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998141"}
{"pmid": "20998142", "title": "Aberrant Y chromosomes and sex expression in Melandrium album.", "content": "Aberrant Y chromosomes and sex expression in Melandrium album.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998142"}
{"pmid": "20998143", "title": "The plant species in relation to polyploidy and apomixis.", "content": "The plant species in relation to polyploidy and apomixis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998143"}
{"pmid": "20998144", "title": "Heterochromaty in chromosomes during their contraction phase.", "content": "Heterochromaty in chromosomes during their contraction phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998144"}
{"pmid": "20998145", "title": "Chromosome numbers of twin plants of Quercus robur and Fagus silvatica.", "content": "Chromosome numbers of twin plants of Quercus robur and Fagus silvatica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998145"}
{"pmid": "20998146", "title": "Behaviour on the spindle of the actively mobile chromosome ends of rye.", "content": "Behaviour on the spindle of the actively mobile chromosome ends of rye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998146"}
{"pmid": "20998147", "title": "Meiosis in hybrid nullisomics and certain other forms of Godetia Whitneyi.", "content": "Meiosis in hybrid nullisomics and certain other forms of Godetia Whitneyi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998147"}
{"pmid": "20998148", "title": "Chromosome numbers in Anemone nemorosa and A. ranunculoides.", "content": "Chromosome numbers in Anemone nemorosa and A. ranunculoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998148"}
{"pmid": "20998149", "title": "Sterility in rye populations.", "content": "Sterility in rye populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998149"}
{"pmid": "20998150", "title": "Fetal mortality in breech delivery.", "content": "Fetal mortality in breech delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998150"}
{"pmid": "20998151", "title": "The fetal risk in breech delivery.", "content": "The fetal risk in breech delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998151"}
{"pmid": "20998152", "title": "Maternal obstetric paralysis.", "content": "Maternal obstetric paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998152"}
{"pmid": "20998153", "title": "The anatomic peculiarities of the human umbilical cord and their clinical significance.", "content": "The anatomic peculiarities of the human umbilical cord and their clinical significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998153"}
{"pmid": "20998154", "title": "Composition of the human placenta; proximate composition.", "content": "Composition of the human placenta; proximate composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998154"}
{"pmid": "20998155", "title": "The treatment of psychogynecic disorders by hypnoanalysis.", "content": "The treatment of psychogynecic disorders by hypnoanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998155"}
{"pmid": "20998156", "title": "Abnormal presentations among malformed infants; with suggestions concerning the etiology.", "content": "Abnormal presentations among malformed infants; with suggestions concerning the etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998156"}
{"pmid": "20998157", "title": "High protein, low caloric diet for the prevention of toxemia of pregnancy.", "content": "High protein, low caloric diet for the prevention of toxemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998157"}
{"pmid": "20998158", "title": "A review of one hundred cases of ovarian cancer.", "content": "A review of one hundred cases of ovarian cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998158"}
{"pmid": "20998160", "title": "Hemolytic disease associated with the Rh factor in twin pregnancies.", "content": "Hemolytic disease associated with the Rh factor in twin pregnancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998160"}
{"pmid": "20998159", "title": "Some observations upon the Rh factor in pregnancy.", "content": "Some observations upon the Rh factor in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998159"}
{"pmid": "20998161", "title": "A seven-year history in early cervical cancer.", "content": "A seven-year history in early cervical cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998161"}
{"pmid": "20998163", "title": "Torsion of adnexal tumors and its relation to surgical emergency.", "content": "Torsion of adnexal tumors and its relation to surgical emergency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998163"}
{"pmid": "20998162", "title": "Retroperitoneal tumors simulating genital tract neoplasms.", "content": "Retroperitoneal tumors simulating genital tract neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998162"}
{"pmid": "20998164", "title": "Sickle-cell anemia in pregnancy.", "content": "Sickle-cell anemia in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998164"}
{"pmid": "20998165", "title": "Multiple primary carcinomas.", "content": "Multiple primary carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998165"}
{"pmid": "20998166", "title": "Mesenteric lymphangioma with intestinal obstruction complicating uterine carcinoma and fibromyoma.", "content": "Mesenteric lymphangioma with intestinal obstruction complicating uterine carcinoma and fibromyoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998166"}
{"pmid": "20998167", "title": "Chorionephithelioma in an 8-year-old primigravida.", "content": "Chorionephithelioma in an 8-year-old primigravida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998167"}
{"pmid": "20998169", "title": "Bilateral simultaneous tubal pregnancy.", "content": "Bilateral simultaneous tubal pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998169"}
{"pmid": "20998168", "title": "Cerebrovascular complications of pregnancy.", "content": "Cerebrovascular complications of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998168"}
{"pmid": "20998170", "title": "Absorbable (oxidized) gauze as a hemostatic agent in gynecologic surgery.", "content": "Absorbable (oxidized) gauze as a hemostatic agent in gynecologic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998170"}
{"pmid": "20998171", "title": "Rupture of the posterior vagina during normal coitus.", "content": "Rupture of the posterior vagina during normal coitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998171"}
{"pmid": "20998172", "title": "Simplified apparatus for insufflation of the tubes with carbon dioxide.", "content": "Simplified apparatus for insufflation of the tubes with carbon dioxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998172"}
{"pmid": "20998173", "title": "A new introducer and cannula for obstetric and surgical cases suitable for caudal analgesia.", "content": "A new introducer and cannula for obstetric and surgical cases suitable for caudal analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998173"}
{"pmid": "20998174", "title": "Air cystoscope with a universal handle and external light.", "content": "Air cystoscope with a universal handle and external light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998174"}
{"pmid": "20998175", "title": "Retention catheter.", "content": "Retention catheter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998175"}
{"pmid": "20998176", "title": "See-saw resuscitator for the treatment of asphyxia in the newborn.", "content": "See-saw resuscitator for the treatment of asphyxia in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998176"}
{"pmid": "20998177", "title": "Government sponsorship of a maternity program in wartime; can it be successfully perpetuated in peacetime?", "content": "Government sponsorship of a maternity program in wartime; can it be successfully perpetuated in peacetime?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998177"}
{"pmid": "20998178", "title": "Bibliography of the modern South Arabic languages.", "content": "Bibliography of the modern South Arabic languages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998178"}
{"pmid": "20998179", "title": "The dance of death.", "content": "The dance of death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998179"}
{"pmid": "20998182", "title": "High fluid intake in cardiac edema and in dehydrated states in congestive failure.", "content": "High fluid intake in cardiac edema and in dehydrated states in congestive failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998182"}
{"pmid": "20998183", "title": "Rheumatic valvular disease in soldiers.", "content": "Rheumatic valvular disease in soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998183"}
{"pmid": "20998185", "title": "Notes on the diabetic patient as a surgical risk.", "content": "Notes on the diabetic patient as a surgical risk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998185"}
{"pmid": "20998184", "title": "The diagnosis and treatment of meningococcus septicemia.", "content": "The diagnosis and treatment of meningococcus septicemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998184"}
{"pmid": "20998186", "title": "Cures with myristica.", "content": "Cures with myristica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998186"}
{"pmid": "20998187", "title": "History taking for the general practitioner.", "content": "History taking for the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998187"}
{"pmid": "20998190", "title": "MATERNITY welfare in Norway.", "content": "MATERNITY welfare in Norway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998190"}
{"pmid": "20998191", "title": "Present day concept of tuberculosis care.", "content": "Present day concept of tuberculosis care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998191"}
{"pmid": "20998192", "title": "COMPETITIVE designs for 12-bed hospital-health centre.", "content": "COMPETITIVE designs for 12-bed hospital-health centre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998192"}
{"pmid": "20998180", "title": "Bibliotherapy and the librarian.", "content": "Bibliotherapy and the librarian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998180"}
{"pmid": "20998194", "title": "NEW Medical Centre, Basle.", "content": "NEW Medical Centre, Basle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998194"}
{"pmid": "20998193", "title": "UNIT of rheumatology.", "content": "UNIT of rheumatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998193"}
{"pmid": "20998181", "title": "The approach of the librarian to the neuropsychiatric patient in an Army general hospital.", "content": "The approach of the librarian to the neuropsychiatric patient in an Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998181"}
{"pmid": "20998195", "title": "Engineering in hospitals; vocal signalling systems.", "content": "Engineering in hospitals; vocal signalling systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998195"}
{"pmid": "20998196", "title": "Changing concepts in the functions of hospitals; vital considerations in design.", "content": "Changing concepts in the functions of hospitals; vital considerations in design.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998196"}
{"pmid": "20998197", "title": "DIABETIC children.", "content": "DIABETIC children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998197"}
{"pmid": "20998199", "title": "How much should the hospital cost; where can money be saved?", "content": "How much should the hospital cost; where can money be saved?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998199"}
{"pmid": "20998198", "title": "Pennsylvania Hospital, 195 years young, awaits Convention visitors.", "content": "Pennsylvania Hospital, 195 years young, awaits Convention visitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998198"}
{"pmid": "20998200", "title": "HUMAN Milk Bank; administration at Queen Charlotte's Hospital, London.", "content": "HUMAN Milk Bank; administration at Queen Charlotte's Hospital, London.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998200"}
{"pmid": "20998201", "title": "Patients' wills.", "content": "Patients' wills.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998201"}
{"pmid": "20998202", "title": "Survey indicates patients pay $1 a day below costs.", "content": "Survey indicates patients pay $1 a day below costs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998202"}
{"pmid": "20998203", "title": "Normal occupancy rate in the general hospital.", "content": "Normal occupancy rate in the general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998203"}
{"pmid": "20998204", "title": "Rural hospital and nursing school.", "content": "Rural hospital and nursing school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998204"}
{"pmid": "20998205", "title": "Medications for outpatients; operating a successful dispensary.", "content": "Medications for outpatients; operating a successful dispensary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998205"}
{"pmid": "20998206", "title": "Medicine is practiced in and not by hospitals.", "content": "Medicine is practiced in and not by hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998206"}
{"pmid": "20998207", "title": "A study of bed distribution according to length of stay.", "content": "A study of bed distribution according to length of stay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998207"}
{"pmid": "20998208", "title": "Hospitals, morticians and pathologists develop a working agreement.", "content": "Hospitals, morticians and pathologists develop a working agreement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998208"}
{"pmid": "20998209", "title": "The nurse and hospital maintenance.", "content": "The nurse and hospital maintenance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998209"}
{"pmid": "20998210", "title": "Care and upkeep of fine instruments.", "content": "Care and upkeep of fine instruments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998210"}
{"pmid": "20998212", "title": "OCCURRENCE of Aedes aegypti in British Guiana.", "content": "OCCURRENCE of Aedes aegypti in British Guiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998212"}
{"pmid": "20998211", "title": "The practical nurse vocation.", "content": "The practical nurse vocation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998211"}
{"pmid": "20998213", "title": "PRESENT status of A. aegypti control.", "content": "PRESENT status of A. aegypti control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998213"}
{"pmid": "20998214", "title": "EXPERIMENTAL control of mosquitoes on trains by spraying with pyrethrum aerosols and DDT solutions.", "content": "EXPERIMENTAL control of mosquitoes on trains by spraying with pyrethrum aerosols and DDT solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998214"}
{"pmid": "20998215", "title": "MEMORANDUM on yellow fever in British Guiana.", "content": "MEMORANDUM on yellow fever in British Guiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998215"}
{"pmid": "20998216", "title": "The influence of the respiration on the circulation in man; with special reference to pressures in the right auricle, right ventricle, femoral artery and peripheral veins.", "content": "The influence of the respiration on the circulation in man; with special reference to pressures in the right auricle, right ventricle, femoral artery and peripheral veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998216"}
{"pmid": "20998217", "title": "Clinical syndrome of potassium intoxication.", "content": "Clinical syndrome of potassium intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998217"}
{"pmid": "20998218", "title": "The clinical manifestations of subacute bacterial endocarditis caused by streptococcus s. b. e.", "content": "The clinical manifestations of subacute bacterial endocarditis caused by streptococcus s. b. e.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998218"}
{"pmid": "20998219", "title": "Radiophosphorus as the treatment of choice in primary polycythemia.", "content": "Radiophosphorus as the treatment of choice in primary polycythemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998219"}
{"pmid": "20998220", "title": "Reciprocal influences of bronchial asthma and pregnancy.", "content": "Reciprocal influences of bronchial asthma and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998220"}
{"pmid": "20998221", "title": "The diagnosis and management of rheumatic fever.", "content": "The diagnosis and management of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998221"}
{"pmid": "20998222", "title": "Industrial exposures to chlorinated hydrocarbons.", "content": "Industrial exposures to chlorinated hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998222"}
{"pmid": "20998223", "title": "The current status of calcium penicillin in beeswax and peanut oil; data from a study of 600 cases and clinical observation of 4,000 patients given 60,000 injections.", "content": "The current status of calcium penicillin in beeswax and peanut oil; data from a study of 600 cases and clinical observation of 4,000 patients given 60,000 injections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998223"}
{"pmid": "20998224", "title": "Hypoglycemia.", "content": "Hypoglycemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998224"}
{"pmid": "20998225", "title": "Fever of unknown origin.", "content": "Fever of unknown origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998225"}
{"pmid": "20998226", "title": "Cranial arteritis; a review of the literature with report of a case with total blindness.", "content": "Cranial arteritis; a review of the literature with report of a case with total blindness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998226"}
{"pmid": "20998227", "title": "Tropical ulcers and cutaneous diphtheria.", "content": "Tropical ulcers and cutaneous diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998227"}
{"pmid": "20998228", "title": "Methemoglobinemia; treatment with ascorbic acid.", "content": "Methemoglobinemia; treatment with ascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998228"}
{"pmid": "20998230", "title": "Treatment of gummatous hepatic syphilis with penicillin.", "content": "Treatment of gummatous hepatic syphilis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998230"}
{"pmid": "20998229", "title": "Löffler's syndrome associated with creeping eruption (cutaneous helminthiasis).", "content": "Löffler's syndrome associated with creeping eruption (cutaneous helminthiasis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998229"}
{"pmid": "20998231", "title": "Gastroenterology; a review of the literature from July 1944 to June 1945.", "content": "Gastroenterology; a review of the literature from July 1944 to June 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998231"}
{"pmid": "20998244", "title": "CITY of Buffalo vs. tuberculosis death rate.", "content": "CITY of Buffalo vs. tuberculosis death rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998244"}
{"pmid": "20998249", "title": "General pathology of tumors of endocrine glands.", "content": "General pathology of tumors of endocrine glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998249"}
{"pmid": "20998250", "title": "Recent advances in the use of curare in clinical practice.", "content": "Recent advances in the use of curare in clinical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998250"}
{"pmid": "20998251", "title": "Summary of the present status of our knowledge of the factors controlling blood pressure.", "content": "Summary of the present status of our knowledge of the factors controlling blood pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998251"}
{"pmid": "20998252", "title": "Apical systolic murmurs in incipient rheumatic heart disease.", "content": "Apical systolic murmurs in incipient rheumatic heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998252"}
{"pmid": "20998253", "title": "SUMMARY and recommendations of report on planned parenthood clinics by the Committee on Public Health Relations of the New York Academy of Medicine.", "content": "SUMMARY and recommendations of report on planned parenthood clinics by the Committee on Public Health Relations of the New York Academy of Medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998253"}
{"pmid": "20998254", "title": "The effect of ante-natal conditions on the new-born child.", "content": "The effect of ante-natal conditions on the new-born child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998254"}
{"pmid": "20998255", "title": "Is amoebiasis a medical problem in Canada?", "content": "Is amoebiasis a medical problem in Canada?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998255"}
{"pmid": "20998256", "title": "The treatment of some surgical complications in amoebiasis.", "content": "The treatment of some surgical complications in amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998256"}
{"pmid": "20998257", "title": "The role of the emotions in the production of cardiovascular disturbances.", "content": "The role of the emotions in the production of cardiovascular disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998257"}
{"pmid": "20998258", "title": "Carcinoma of the bladder.", "content": "Carcinoma of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998258"}
{"pmid": "20998259", "title": "Combined use of sodium pentothal, intocostrin (curare), nitrous oxide.", "content": "Combined use of sodium pentothal, intocostrin (curare), nitrous oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998259"}
{"pmid": "20998261", "title": "The role of the general practitioner in the diagnosis of glaucoma.", "content": "The role of the general practitioner in the diagnosis of glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998261"}
{"pmid": "20998260", "title": "The use of anthallan in dermatology.", "content": "The use of anthallan in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998260"}
{"pmid": "20998262", "title": "Surgical treatment of cancer of the larynx.", "content": "Surgical treatment of cancer of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998262"}
{"pmid": "20998264", "title": "Enuresis.", "content": "Enuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998264"}
{"pmid": "20998263", "title": "Tuberculosis in the naval service from 1930 to 1945 (inclusive).", "content": "Tuberculosis in the naval service from 1930 to 1945 (inclusive).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998263"}
{"pmid": "20998265", "title": "Chronic non-specific thyroiditis.", "content": "Chronic non-specific thyroiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998265"}
{"pmid": "20998267", "title": "Solid teratoma of the ovary.", "content": "Solid teratoma of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998267"}
{"pmid": "20998268", "title": "Case of lymphogranuloma venereum (poradenolymphitis) in a white female.", "content": "Case of lymphogranuloma venereum (poradenolymphitis) in a white female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998268"}
{"pmid": "20998269", "title": "Generalized oedema associated with hypoproteinaemia.", "content": "Generalized oedema associated with hypoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998269"}
{"pmid": "20998266", "title": "Primitive reticulo-sarcoma of the kidney.", "content": "Primitive reticulo-sarcoma of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998266"}
{"pmid": "20998271", "title": "Mobilizing the quadriceps to increase active movement in stiff knees.", "content": "Mobilizing the quadriceps to increase active movement in stiff knees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998271"}
{"pmid": "20998270", "title": "The World Health Organization.", "content": "The World Health Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998270"}
{"pmid": "20998272", "title": "Early medicine of Vancouver Island.", "content": "Early medicine of Vancouver Island.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998272"}
{"pmid": "20998274", "title": "Clinical uses of the products of human plasma fractionation.", "content": "Clinical uses of the products of human plasma fractionation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998274"}
{"pmid": "20998273", "title": "Some reflections upon the health and mortality of cotton textile workers.", "content": "Some reflections upon the health and mortality of cotton textile workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998273"}
{"pmid": "20998275", "title": "Respiratory tract cancer deaths in relation to atmospheric pollution in Cincinnati.", "content": "Respiratory tract cancer deaths in relation to atmospheric pollution in Cincinnati.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998275"}
{"pmid": "20998276", "title": "Blood levels and urinary excretion of penicillin after oral administration.", "content": "Blood levels and urinary excretion of penicillin after oral administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998276"}
{"pmid": "20998278", "title": "Syphilitic aneurysm of the ascending arch of the aorta.", "content": "Syphilitic aneurysm of the ascending arch of the aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998278"}
{"pmid": "20998277", "title": "Folic acid (Lactobacillus casei factor, liver vitamin Bc).", "content": "Folic acid (Lactobacillus casei factor, liver vitamin Bc).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998277"}
{"pmid": "20998279", "title": "President's inaugural address [social medicine].", "content": "President's inaugural address [social medicine].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998279"}
{"pmid": "20998280", "title": "The health needs of the people.", "content": "The health needs of the people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998280"}
{"pmid": "20998281", "title": "Connecticut's rank among the states with respect to various health factors.", "content": "Connecticut's rank among the states with respect to various health factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998281"}
{"pmid": "20998282", "title": "Probable echinococcus disease of the heart.", "content": "Probable echinococcus disease of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998282"}
{"pmid": "20998284", "title": "On community cooperation for health.", "content": "On community cooperation for health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998284"}
{"pmid": "20998283", "title": "Health legislation beneficial to the people.", "content": "Health legislation beneficial to the people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998283"}
{"pmid": "20998285", "title": "The chest lead diagram of the normal heart.", "content": "The chest lead diagram of the normal heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998285"}
{"pmid": "20998286", "title": "Ethylenediamine dihydrochloride or chlor-ethamine.", "content": "Ethylenediamine dihydrochloride or chlor-ethamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998286"}
{"pmid": "20998287", "title": "Ethylenediamine dihydrochloride or chlor-ethamine; untoward and toxic reactions.", "content": "Ethylenediamine dihydrochloride or chlor-ethamine; untoward and toxic reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998287"}
{"pmid": "20998288", "title": "Ethylenediamine dihydrochloride or chlor-ethamine; as a diuretic.", "content": "Ethylenediamine dihydrochloride or chlor-ethamine; as a diuretic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998288"}
{"pmid": "20998289", "title": "The cannon sound and other intensified single heart sounds.", "content": "The cannon sound and other intensified single heart sounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998289"}
{"pmid": "20998290", "title": "Carbohydrate content of serum proteins in normal and toxemic pregnancy.", "content": "Carbohydrate content of serum proteins in normal and toxemic pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998290"}
{"pmid": "20998291", "title": "Coagulation defect in the shocks produced by trypsin, peptone and ascaris extracts.", "content": "Coagulation defect in the shocks produced by trypsin, peptone and ascaris extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998291"}
{"pmid": "20998292", "title": "The influence of wheat germ oil on the production of tumors in rats by methylcholanthrene.", "content": "The influence of wheat germ oil on the production of tumors in rats by methylcholanthrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998292"}
{"pmid": "20998293", "title": "The surgery of divided digital tendons.", "content": "The surgery of divided digital tendons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998293"}
{"pmid": "20998297", "title": "One thousand cases of bubonic plague treated in an emergency plague hospital.", "content": "One thousand cases of bubonic plague treated in an emergency plague hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998297"}
{"pmid": "20998295", "title": "An analytical study of intestinal protozoal infection with special reference to amoebiasis.", "content": "An analytical study of intestinal protozoal infection with special reference to amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998295"}
{"pmid": "20998294", "title": "Some not well-known manifestations of riboflavin deficiency.", "content": "Some not well-known manifestations of riboflavin deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998294"}
{"pmid": "20998296", "title": "The effect of sulphadiazine and penicillin on experimental animal plague.", "content": "The effect of sulphadiazine and penicillin on experimental animal plague.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998296"}
{"pmid": "20998298", "title": "A case of quinine amblyopia.", "content": "A case of quinine amblyopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998298"}
{"pmid": "20998310", "title": "Optimism in medicine.", "content": "Optimism in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998310"}
{"pmid": "20998301", "title": "A presumptive case of erythroblastosis foetalis due to Rh incompatibility.", "content": "A presumptive case of erythroblastosis foetalis due to Rh incompatibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998301"}
{"pmid": "20998299", "title": "A case of juvenile disciform macular degeneration.", "content": "A case of juvenile disciform macular degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998299"}
{"pmid": "20998311", "title": "Experimental human bacillary dysentery; polyvalent dysentery vaccine in its prevention.", "content": "Experimental human bacillary dysentery; polyvalent dysentery vaccine in its prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998311"}
{"pmid": "20998312", "title": "Penicillin in the treatment of syphilis in children.", "content": "Penicillin in the treatment of syphilis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998312"}
{"pmid": "20998300", "title": "Pedunculine (for treatment of Bengal splenomegaly).", "content": "Pedunculine (for treatment of Bengal splenomegaly).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998300"}
{"pmid": "20998313", "title": "Diverticulosis and diverticulitis of the colon in young people.", "content": "Diverticulosis and diverticulitis of the colon in young people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998313"}
{"pmid": "20998303", "title": "Curative treatment of lathyrism, a disease of the nervous system.", "content": "Curative treatment of lathyrism, a disease of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998303"}
{"pmid": "20998314", "title": "The endocrine regulation of carbohydrate metabolism.", "content": "The endocrine regulation of carbohydrate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998314"}
{"pmid": "20998315", "title": "Tuberculous meningitis treated with streptomycin.", "content": "Tuberculous meningitis treated with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998315"}
{"pmid": "20998302", "title": "Prothrombin time in normal Indians.", "content": "Prothrombin time in normal Indians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998302"}
{"pmid": "20998316", "title": "Clinical applications of chick embryo cultures; adaptation for use by the general practitioner in bacteriologic diagnosis of clinical problems.", "content": "Clinical applications of chick embryo cultures; adaptation for use by the general practitioner in bacteriologic diagnosis of clinical problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998316"}
{"pmid": "20998317", "title": "Sources of ultraviolet and infra-red radiation used in therapy; physical characteristics.", "content": "Sources of ultraviolet and infra-red radiation used in therapy; physical characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998317"}
{"pmid": "20998304", "title": "The electron microscope and its use in biology.", "content": "The electron microscope and its use in biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998304"}
{"pmid": "20998306", "title": "Treatment of Oriental sore by x-rays.", "content": "Treatment of Oriental sore by x-rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998306"}
{"pmid": "20998307", "title": "A case of gonorrhoeal pyelonephritis.", "content": "A case of gonorrhoeal pyelonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998307"}
{"pmid": "20998308", "title": "Tellural hospitals in India for non-tropical diseases; a post-war proposition.", "content": "Tellural hospitals in India for non-tropical diseases; a post-war proposition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998308"}
{"pmid": "20998318", "title": "What is wrong with the dyspeptic whose findings are all negative?", "content": "What is wrong with the dyspeptic whose findings are all negative?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998318"}
{"pmid": "20998319", "title": "Treatment of subacute bacterial endocarditis.", "content": "Treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998319"}
{"pmid": "20998305", "title": "Diabetes insipidus treated with pitressin, atropine, esidrone and tincture belladonna.", "content": "Diabetes insipidus treated with pitressin, atropine, esidrone and tincture belladonna.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998305"}
{"pmid": "20998320", "title": "The problem of certain animal diseases prevalent in Iowa as related to human medicine.", "content": "The problem of certain animal diseases prevalent in Iowa as related to human medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998320"}
{"pmid": "20998321", "title": "Congenital cystic malformation of the lung; differential diagnosis and pathologic characteristics in twenty-one cases.", "content": "Congenital cystic malformation of the lung; differential diagnosis and pathologic characteristics in twenty-one cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998321"}
{"pmid": "20998322", "title": "Reflections on medical education.", "content": "Reflections on medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998322"}
{"pmid": "20998323", "title": "A review of studies on immunity to vivax malaria.", "content": "A review of studies on immunity to vivax malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998323"}
{"pmid": "20998325", "title": "Carcinoma of the lung with intracranial and skeletal metastases.", "content": "Carcinoma of the lung with intracranial and skeletal metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998325"}
{"pmid": "20998324", "title": "The doctor treats the patient.", "content": "The doctor treats the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998324"}
{"pmid": "20998326", "title": "The Iowa doctor one hundred years ago.", "content": "The Iowa doctor one hundred years ago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998326"}
{"pmid": "20998309", "title": "The teaching of epidemiology in India.", "content": "The teaching of epidemiology in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998309"}
{"pmid": "20998328", "title": "The significance of recently developed tests of renal function.", "content": "The significance of recently developed tests of renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998328"}
{"pmid": "20998329", "title": "Clinical correlations between renal disease and hypertension.", "content": "Clinical correlations between renal disease and hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998329"}
{"pmid": "20998330", "title": "Renal lithiasis; recent advances in treatment.", "content": "Renal lithiasis; recent advances in treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998330"}
{"pmid": "20998331", "title": "Renal insufficiency in diseases other than those of the kidneys and urinary tract.", "content": "Renal insufficiency in diseases other than those of the kidneys and urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998331"}
{"pmid": "20998332", "title": "Spontaneous rupture of the spleen in benign tertian malaria.", "content": "Spontaneous rupture of the spleen in benign tertian malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998332"}
{"pmid": "20998333", "title": "A graphic approach to a compleat anatomy.", "content": "A graphic approach to a compleat anatomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998333"}
{"pmid": "20998334", "title": "Vibration sense.", "content": "Vibration sense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998334"}
{"pmid": "20998335", "title": "Recent advances in the therapy of glaucoma.", "content": "Recent advances in the therapy of glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998335"}
{"pmid": "20998336", "title": "The histologic and clinical response of human cancer to irradiation.", "content": "The histologic and clinical response of human cancer to irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998336"}
{"pmid": "20998342", "title": "A clinical adaptation of the psychopathologies.", "content": "A clinical adaptation of the psychopathologies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998342"}
{"pmid": "20998343", "title": "A rational approach to endocrine therapy in gynecology.", "content": "A rational approach to endocrine therapy in gynecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998343"}
{"pmid": "20998344", "title": "Problems in abdominal surgery.", "content": "Problems in abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998344"}
{"pmid": "20998346", "title": "Recent advances in surgical technic and management of surgical cases.", "content": "Recent advances in surgical technic and management of surgical cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998346"}
{"pmid": "20998345", "title": "Diagnosis of lesions of the terminal portion of the colon.", "content": "Diagnosis of lesions of the terminal portion of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998345"}
{"pmid": "20998347", "title": "DDT in medical practice.", "content": "DDT in medical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998347"}
{"pmid": "20998349", "title": "Arteriosclerosis; present status of concepts.", "content": "Arteriosclerosis; present status of concepts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998349"}
{"pmid": "20998350", "title": "The Laura Memorial Woman's Medical College.", "content": "The Laura Memorial Woman's Medical College.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998350"}
{"pmid": "20998348", "title": "Penicillin for pleural effusion.", "content": "Penicillin for pleural effusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998348"}
{"pmid": "20998358", "title": "Tuberculosis del epididimo.", "content": "Tuberculosis del epididimo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998358"}
{"pmid": "20998375", "title": "Congenital heart disease.", "content": "Congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998375"}
{"pmid": "20998376", "title": "Physiologic therapy of respiratory disease; with special reference to the management of pulmonary emphysema.", "content": "Physiologic therapy of respiratory disease; with special reference to the management of pulmonary emphysema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998376"}
{"pmid": "20998377", "title": "The influence of clinical training on the medicine of tomorrow.", "content": "The influence of clinical training on the medicine of tomorrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998377"}
{"pmid": "20998378", "title": "Urological complications of pregnancy and labor.", "content": "Urological complications of pregnancy and labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998378"}
{"pmid": "20998379", "title": "Syphilis and penicillin therapy.", "content": "Syphilis and penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998379"}
{"pmid": "20998381", "title": "The cancer control program.", "content": "The cancer control program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998381"}
{"pmid": "20998380", "title": "Progress in the elimination of permanent colostomies in carcinoma of the rectum and rectosigmoid.", "content": "Progress in the elimination of permanent colostomies in carcinoma of the rectum and rectosigmoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998380"}
{"pmid": "20998382", "title": "Congenital atresia of the bile ducts.", "content": "Congenital atresia of the bile ducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998382"}
{"pmid": "20998383", "title": "Pathological aspects of carcinoma of the stomach.", "content": "Pathological aspects of carcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998383"}
{"pmid": "20998384", "title": "Penicillin in the treatment of tetanus.", "content": "Penicillin in the treatment of tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998384"}
{"pmid": "20998393", "title": "ROENTGEN studies of spastic phenomena of the gastrointestinal tract.", "content": "ROENTGEN studies of spastic phenomena of the gastrointestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998393"}
{"pmid": "20998394", "title": "INNERVATION of the stomach.", "content": "INNERVATION of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998394"}
{"pmid": "20998395", "title": "PHARMACOLOGY of pavatrine.", "content": "PHARMACOLOGY of pavatrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998395"}
{"pmid": "20998401", "title": "A plan for improving hospital treatment of psychiatric patients.", "content": "A plan for improving hospital treatment of psychiatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998401"}
{"pmid": "20998402", "title": "A consideration of the urological care of paraplegics.", "content": "A consideration of the urological care of paraplegics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998402"}
{"pmid": "20998403", "title": "Cataract surgery, recent developments.", "content": "Cataract surgery, recent developments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998403"}
{"pmid": "20998404", "title": "Medical care; whose responsibility?", "content": "Medical care; whose responsibility?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998404"}
{"pmid": "20998405", "title": "Prostatic obstruction and the mental patient.", "content": "Prostatic obstruction and the mental patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998405"}
{"pmid": "20998406", "title": "Spontaneous rupture of the normal and abnormal spleen.", "content": "Spontaneous rupture of the normal and abnormal spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998406"}
{"pmid": "20998407", "title": "Hernia.", "content": "Hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998407"}
{"pmid": "20998411", "title": "Thermal burns.", "content": "Thermal burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998411"}
{"pmid": "20998412", "title": "Thrombophlebitis, phlebothrombosis and pulmonary embolism.", "content": "Thrombophlebitis, phlebothrombosis and pulmonary embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998412"}
{"pmid": "20998413", "title": "Coliform contamination of eggs.", "content": "Coliform contamination of eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998413"}
{"pmid": "20998414", "title": "Precision of assessment of palatability of foodstuffs by laboratory panels.", "content": "Precision of assessment of palatability of foodstuffs by laboratory panels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998414"}
{"pmid": "20998415", "title": "The effect of grade of eggs, locality and month of production, and climatic conditions on the solids content of liquid egg and on the quality of the powder produced.", "content": "The effect of grade of eggs, locality and month of production, and climatic conditions on the solids content of liquid egg and on the quality of the powder produced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998415"}
{"pmid": "20998416", "title": "An air-base stereoscope.", "content": "An air-base stereoscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998416"}
{"pmid": "20998417", "title": "Production and properties of 2,3-butanediol; the occurrence of acetone as a product of the Aerobacillus polymyxa fermentation.", "content": "Production and properties of 2,3-butanediol; the occurrence of acetone as a product of the Aerobacillus polymyxa fermentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998417"}
{"pmid": "20998418", "title": "Pasteurization of liquid egg and its effect on quality of the powder.", "content": "Pasteurization of liquid egg and its effect on quality of the powder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998418"}
{"pmid": "20998419", "title": "Two accessories for the electron microscope laboratory; (A) specimen stage, (B) plate reader.", "content": "Two accessories for the electron microscope laboratory; (A) specimen stage, (B) plate reader.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998419"}
{"pmid": "20998420", "title": "The eternal glory of Ayurveda.", "content": "The eternal glory of Ayurveda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998420"}
{"pmid": "20998421", "title": "Nutritional improvement of rice.", "content": "Nutritional improvement of rice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998421"}
{"pmid": "20998422", "title": "A home-made infra-red spectrometer.", "content": "A home-made infra-red spectrometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998422"}
{"pmid": "20998423", "title": "Chemistry of kurchi seeds; a new and simple method of analysis of bromoglycerides.", "content": "Chemistry of kurchi seeds; a new and simple method of analysis of bromoglycerides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998423"}
{"pmid": "20998424", "title": "An unusual mode of egg-laying in Schistocerca gregaria Forsk; and its causes.", "content": "An unusual mode of egg-laying in Schistocerca gregaria Forsk; and its causes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998424"}
{"pmid": "20998425", "title": "D. D. T. and ox warble control.", "content": "D. D. T. and ox warble control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998425"}
{"pmid": "20998431", "title": "More filed Indian teeth from the United States.", "content": "More filed Indian teeth from the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998431"}
{"pmid": "20998432", "title": "The Aedes (Finlaya) niveus subgroup of Oriental mosquitoes.", "content": "The Aedes (Finlaya) niveus subgroup of Oriental mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998432"}
{"pmid": "20998434", "title": "Descriptions of three new species of mosquitoes of the genus Aedes, subgenus Finlaya, from New Guinea.", "content": "Descriptions of three new species of mosquitoes of the genus Aedes, subgenus Finlaya, from New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998434"}
{"pmid": "20998435", "title": "Notes on some Ashmeadian genotypes in the hymenopterous super-family Chalcidoidea.", "content": "Notes on some Ashmeadian genotypes in the hymenopterous super-family Chalcidoidea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998435"}
{"pmid": "20998436", "title": "Ethnoherpetology of the Catawl and Cherokee Indians.", "content": "Ethnoherpetology of the Catawl and Cherokee Indians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998436"}
{"pmid": "20998445", "title": "The World Health Organization.", "content": "The World Health Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998445"}
{"pmid": "20998446", "title": "The metabolism of a very small mammal.", "content": "The metabolism of a very small mammal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998446"}
{"pmid": "20998447", "title": "The milk factor in blood.", "content": "The milk factor in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998447"}
{"pmid": "20998448", "title": "An indwelling arterial needle for use in the radial artery.", "content": "An indwelling arterial needle for use in the radial artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998448"}
{"pmid": "20998449", "title": "Successful use of oxidized cellulose in surgery of the uterus.", "content": "Successful use of oxidized cellulose in surgery of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998449"}
{"pmid": "20998450", "title": "Trophoblast elements in cancer.", "content": "Trophoblast elements in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998450"}
{"pmid": "20998451", "title": "Two kinds of neutrons?", "content": "Two kinds of neutrons?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998451"}
{"pmid": "20998452", "title": "Growth and aging problems in agriculture.", "content": "Growth and aging problems in agriculture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998452"}
{"pmid": "20998453", "title": "Cardiac failure in cattle on vitamin E-free rations as revealed by electrocardiograms.", "content": "Cardiac failure in cattle on vitamin E-free rations as revealed by electrocardiograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998453"}
{"pmid": "20998454", "title": "Influence of purified lignin on nitrification in soil.", "content": "Influence of purified lignin on nitrification in soil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998454"}
{"pmid": "20998455", "title": "Administration of streptomycin in peanut oil and beeswax and in solvecillin.", "content": "Administration of streptomycin in peanut oil and beeswax and in solvecillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998455"}
{"pmid": "20998456", "title": "Effect of di-isopropyl fluorophosphate on the action potential of muscle.", "content": "Effect of di-isopropyl fluorophosphate on the action potential of muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998456"}
{"pmid": "20998457", "title": "A collapsible metal stirrer.", "content": "A collapsible metal stirrer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998457"}
{"pmid": "20998458", "title": "Penicillin blood-level determinations with a Streptococcus dysgalactiae resistant to normal blood inhibitors.", "content": "Penicillin blood-level determinations with a Streptococcus dysgalactiae resistant to normal blood inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998458"}
{"pmid": "20998459", "title": "Aseptic cultivation of excised plant embryos.", "content": "Aseptic cultivation of excised plant embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998459"}
{"pmid": "20998461", "title": "Iron concentrations in cholinesterase preparations.", "content": "Iron concentrations in cholinesterase preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998461"}
{"pmid": "20998460", "title": "Potentiation of the antibiotic activity of aspergillic acid by bismuth.", "content": "Potentiation of the antibiotic activity of aspergillic acid by bismuth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998460"}
{"pmid": "20998463", "title": "An iron-binding component in human blood plasma.", "content": "An iron-binding component in human blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998463"}
{"pmid": "20998462", "title": "The cultural understanding and appreciation of the scientific approach.", "content": "The cultural understanding and appreciation of the scientific approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998462"}
{"pmid": "20998464", "title": "The intestinal absorption of penicillin G.", "content": "The intestinal absorption of penicillin G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998464"}
{"pmid": "20998465", "title": "Toxicity of DDT isomers to some insects affecting man.", "content": "Toxicity of DDT isomers to some insects affecting man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998465"}
{"pmid": "20998466", "title": "Blood sugar level following intravenous glucose in rheumatoid arthritis.", "content": "Blood sugar level following intravenous glucose in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998466"}
{"pmid": "20998467", "title": "Use of perchloric acid as an oxidizing agent.", "content": "Use of perchloric acid as an oxidizing agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998467"}
{"pmid": "20998468", "title": "Binocular vision as affected by relations between uniocular stimulus-patterns in commonplace environments.", "content": "Binocular vision as affected by relations between uniocular stimulus-patterns in commonplace environments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998468"}
{"pmid": "20998469", "title": "Intellectual functions with restricted intakes of B-complex vitamins.", "content": "Intellectual functions with restricted intakes of B-complex vitamins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998469"}
{"pmid": "20998470", "title": "Life with and without institutional guidance.", "content": "Life with and without institutional guidance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998470"}
{"pmid": "20998472", "title": "Transfer of decrement in ocular tasks.", "content": "Transfer of decrement in ocular tasks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998472"}
{"pmid": "20998471", "title": "Some determinants of the circulation of information.", "content": "Some determinants of the circulation of information.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998471"}
{"pmid": "20998473", "title": "Retroactive inhibition as a function of the time of interpolation of the inhibitor between learning and recall.", "content": "Retroactive inhibition as a function of the time of interpolation of the inhibitor between learning and recall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998473"}
{"pmid": "20998475", "title": "Studies in object-preferences; the effect of temporal proximity upon adults' preferences.", "content": "Studies in object-preferences; the effect of temporal proximity upon adults' preferences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998475"}
{"pmid": "20998474", "title": "Visual reaction-time as a function of variations in the stimulus-figure.", "content": "Visual reaction-time as a function of variations in the stimulus-figure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998474"}
{"pmid": "20998476", "title": "TOOLS and terms in recent researches.", "content": "TOOLS and terms in recent researches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998476"}
{"pmid": "20998477", "title": "Some common features of concrete and abstract thinking.", "content": "Some common features of concrete and abstract thinking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998477"}
{"pmid": "20998478", "title": "Psychical research and the mind-body relation.", "content": "Psychical research and the mind-body relation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998478"}
{"pmid": "20998479", "title": "Rhine's Telepathy and clairvoyance reconsidered; a summary, with a digest of comments by six English investigators.", "content": "Rhine's Telepathy and clairvoyance reconsidered; a summary, with a digest of comments by six English investigators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998479"}
{"pmid": "20998480", "title": "Perspective psychical research.", "content": "Perspective psychical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998480"}
{"pmid": "20998481", "title": "The Psychological Corporation's index of public opinion.", "content": "The Psychological Corporation's index of public opinion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998481"}
{"pmid": "20998482", "title": "Studies in job evaluation; analysis of another point rating scale for hourly-paid jobs and the adequacy of an abbreviated scale.", "content": "Studies in job evaluation; analysis of another point rating scale for hourly-paid jobs and the adequacy of an abbreviated scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998482"}
{"pmid": "20998483", "title": "Test validation on remote criteria.", "content": "Test validation on remote criteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998483"}
{"pmid": "20998484", "title": "The development and standardization of a new type test of peripheral vision.", "content": "The development and standardization of a new type test of peripheral vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998484"}
{"pmid": "20998485", "title": "Statistical laboratory for vision tests at Purdue University.", "content": "Statistical laboratory for vision tests at Purdue University.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998485"}
{"pmid": "20998486", "title": "Motor performance of normal young men maintained on restricted intakes of vitamin B complex.", "content": "Motor performance of normal young men maintained on restricted intakes of vitamin B complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998486"}
{"pmid": "20998488", "title": "The time appreciation test.", "content": "The time appreciation test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998488"}
{"pmid": "20998487", "title": "Standardization of a test of hand strength.", "content": "Standardization of a test of hand strength.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998487"}
{"pmid": "20998489", "title": "The effect of retention of varying degrees of motivation during learning in rats.", "content": "The effect of retention of varying degrees of motivation during learning in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998489"}
{"pmid": "20998490", "title": "Note on gnawing in the gray Norway rat and its coat-character derivative strains.", "content": "Note on gnawing in the gray Norway rat and its coat-character derivative strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998490"}
{"pmid": "20998491", "title": "Experimentally induced convulsive reactions of laboratory rats; a comparative study of the immediate reactions.", "content": "Experimentally induced convulsive reactions of laboratory rats; a comparative study of the immediate reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998491"}
{"pmid": "20998493", "title": "The significance of tonal memory for musicality.", "content": "The significance of tonal memory for musicality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998493"}
{"pmid": "20998492", "title": "Sensory pre-conditioning and the convulsions associated with magnesium deficiency in the rat.", "content": "Sensory pre-conditioning and the convulsions associated with magnesium deficiency in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998492"}
{"pmid": "20998494", "title": "Studies in nervous movements; the effect of mechanical inhibition of movements in one category of the frequency and patterning of movements in other categories.", "content": "Studies in nervous movements; the effect of mechanical inhibition of movements in one category of the frequency and patterning of movements in other categories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998494"}
{"pmid": "20998495", "title": "The validity of the Multiple Choice Group Rorschach test in the screening of naval personnel.", "content": "The validity of the Multiple Choice Group Rorschach test in the screening of naval personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998495"}
{"pmid": "20998496", "title": "Significant incidental factors in the measurement of auditory sensitivity.", "content": "Significant incidental factors in the measurement of auditory sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998496"}
{"pmid": "20998498", "title": "An experimental study of the reactions of neurotics to experiences of success and failure.", "content": "An experimental study of the reactions of neurotics to experiences of success and failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998498"}
{"pmid": "20998497", "title": "The psychology of art appreciation.", "content": "The psychology of art appreciation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998497"}
{"pmid": "20998500", "title": "The inclusion of both physiological and acquired needs in a behavioristic system.", "content": "The inclusion of both physiological and acquired needs in a behavioristic system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998500"}
{"pmid": "20998499", "title": "Spatial effects in human visual resolution.", "content": "Spatial effects in human visual resolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998499"}
{"pmid": "20998501", "title": "Expectancy versus performance in hypnosis.", "content": "Expectancy versus performance in hypnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998501"}
{"pmid": "20998502", "title": "Psychiatric plans of the United States Public Health Service.", "content": "Psychiatric plans of the United States Public Health Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998502"}
{"pmid": "20998504", "title": "A prospectus for mental hygiene.", "content": "A prospectus for mental hygiene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998504"}
{"pmid": "20998503", "title": "The rehabilitation of delinquents in the Army.", "content": "The rehabilitation of delinquents in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998503"}
{"pmid": "20998505", "title": "Paired comparisons and the logic of measurement.", "content": "Paired comparisons and the logic of measurement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998505"}
{"pmid": "20998506", "title": "Repetition and learning; memory and thought.", "content": "Repetition and learning; memory and thought.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998506"}
{"pmid": "20998507", "title": "The history of dream theory.", "content": "The history of dream theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998507"}
{"pmid": "20998508", "title": "Age as a factor in the recall of interrupted tasks.", "content": "Age as a factor in the recall of interrupted tasks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998508"}
{"pmid": "20998509", "title": "The meaning of explanation.", "content": "The meaning of explanation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998509"}
{"pmid": "20998510", "title": "Operationism and psychological theory; a note.", "content": "Operationism and psychological theory; a note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998510"}
{"pmid": "20998512", "title": "Preventive medicine.", "content": "Preventive medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998512"}
{"pmid": "20998511", "title": "Inaugural address to the Health Congress at Blackpool, June 3, 1946.", "content": "Inaugural address to the Health Congress at Blackpool, June 3, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998511"}
{"pmid": "20998513", "title": "The social pathology of rheumatic fever.", "content": "The social pathology of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998513"}
{"pmid": "20998514", "title": "The future of the special hospital.", "content": "The future of the special hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998514"}
{"pmid": "20998515", "title": "Heating and the community.", "content": "Heating and the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998515"}
{"pmid": "20998516", "title": "Prefabrication from an architectural point of view.", "content": "Prefabrication from an architectural point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998516"}
{"pmid": "20998517", "title": "Presidential address on the care of children away from their parents.", "content": "Presidential address on the care of children away from their parents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998517"}
{"pmid": "20998518", "title": "Are nurseries necessary to-day?", "content": "Are nurseries necessary to-day?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998518"}
{"pmid": "20998519", "title": "Nurseries and the welfare of children.", "content": "Nurseries and the welfare of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998519"}
{"pmid": "20998520", "title": "The problem of the children deprived of a normal home life.", "content": "The problem of the children deprived of a normal home life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998520"}
{"pmid": "20998521", "title": "Rehabilitation of problem families.", "content": "Rehabilitation of problem families.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998521"}
{"pmid": "20998523", "title": "Pathology in its relation to meat inspection.", "content": "Pathology in its relation to meat inspection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998523"}
{"pmid": "20998522", "title": "Presidential address on the future utilization of veterinary services in agriculture and public health.", "content": "Presidential address on the future utilization of veterinary services in agriculture and public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998522"}
{"pmid": "20998524", "title": "The tuberculin test and the control of bovine tuberculosis.", "content": "The tuberculin test and the control of bovine tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998524"}
{"pmid": "20998525", "title": "Presidential address on food and nutrition.", "content": "Presidential address on food and nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998525"}
{"pmid": "20998527", "title": "The nutritive value of processed animal foods.", "content": "The nutritive value of processed animal foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998527"}
{"pmid": "20998526", "title": "The nutritive value of vegetable products.", "content": "The nutritive value of vegetable products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998526"}
{"pmid": "20998528", "title": "Presidential address on housing and town planning.", "content": "Presidential address on housing and town planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998528"}
{"pmid": "20998529", "title": "Some aspects of heat, light and sound in relation to town planning.", "content": "Some aspects of heat, light and sound in relation to town planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998529"}
{"pmid": "20998531", "title": "Presidential address on local authorities and a national health service.", "content": "Presidential address on local authorities and a national health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998531"}
{"pmid": "20998530", "title": "Form and colour in landscape.", "content": "Form and colour in landscape.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998530"}
{"pmid": "20998532", "title": "The future of paediatrics; the point of view of a consultant and director of a university department of child health.", "content": "The future of paediatrics; the point of view of a consultant and director of a university department of child health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998532"}
{"pmid": "20998533", "title": "The future of paediatrics; the point of view of a maternity and child welfare officer.", "content": "The future of paediatrics; the point of view of a maternity and child welfare officer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998533"}
{"pmid": "20998534", "title": "The future of paediatrics; the point of view of the general practitioner.", "content": "The future of paediatrics; the point of view of the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998534"}
{"pmid": "20998535", "title": "The care of the aged in health and sickness.", "content": "The care of the aged in health and sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998535"}
{"pmid": "20998536", "title": "Presidential address to the Conference of Engineers and Surveyors, Health Congress at Blackpool.", "content": "Presidential address to the Conference of Engineers and Surveyors, Health Congress at Blackpool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998536"}
{"pmid": "20998537", "title": "Roads and traffic problems; the engineer's contribution to road safety.", "content": "Roads and traffic problems; the engineer's contribution to road safety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998537"}
{"pmid": "20998538", "title": "The comparative values of certain sewer sections.", "content": "The comparative values of certain sewer sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998538"}
{"pmid": "20998539", "title": "Presidential address to conference of sanitary inspectors, Health Congress at Blackpool.", "content": "Presidential address to conference of sanitary inspectors, Health Congress at Blackpool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998539"}
{"pmid": "20998540", "title": "Housing and slum clearance; a new approach.", "content": "Housing and slum clearance; a new approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998540"}
{"pmid": "20998541", "title": "Hygiene of food premises.", "content": "Hygiene of food premises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998541"}
{"pmid": "20998542", "title": "Presidential address on the future of the health visitor.", "content": "Presidential address on the future of the health visitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998542"}
{"pmid": "20998543", "title": "Allocation of duties in the Public Health Nursing Service.", "content": "Allocation of duties in the Public Health Nursing Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998543"}
{"pmid": "20998545", "title": "Health education and the health visitor.", "content": "Health education and the health visitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998545"}
{"pmid": "20998544", "title": "Allocation of duties in the Public Health Nursing Service.", "content": "Allocation of duties in the Public Health Nursing Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998544"}
{"pmid": "20998548", "title": "Occupational therapy; can doses be exact?", "content": "Occupational therapy; can doses be exact?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998548"}
{"pmid": "20998549", "title": "Some psychiatric observations on patients with hearing defect.", "content": "Some psychiatric observations on patients with hearing defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998549"}
{"pmid": "20998550", "title": "The responses of patients in a naval hospital to occupational outlets.", "content": "The responses of patients in a naval hospital to occupational outlets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998550"}
{"pmid": "20998551", "title": "Arts and crafts teaching films for occupational therapy with neuropsychiatric patients.", "content": "Arts and crafts teaching films for occupational therapy with neuropsychiatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998551"}
{"pmid": "20998552", "title": "Training amputees in Britain.", "content": "Training amputees in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998552"}
{"pmid": "20998553", "title": "An analysis of the role and function of educational reconditioning; with particular reference to the program at Welch Convalescent Hospital.", "content": "An analysis of the role and function of educational reconditioning; with particular reference to the program at Welch Convalescent Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998553"}
{"pmid": "20998554", "title": "Physical medicine and rehabilitation; organization of the physical medicine program and its development in relation to occupational therapy.", "content": "Physical medicine and rehabilitation; organization of the physical medicine program and its development in relation to occupational therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998554"}
{"pmid": "20998556", "title": "The medical rehabilitation program in the Veterans Administration.", "content": "The medical rehabilitation program in the Veterans Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998556"}
{"pmid": "20998555", "title": "Coordinating occupational therapy and physical medicine in the Veterans Administration hospitals.", "content": "Coordinating occupational therapy and physical medicine in the Veterans Administration hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998555"}
{"pmid": "20998546", "title": "REHABILITATION to-day and to-morrow.", "content": "REHABILITATION to-day and to-morrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998546"}
{"pmid": "20998557", "title": "Electric shock therapy with reference to occupational therapy.", "content": "Electric shock therapy with reference to occupational therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998557"}
{"pmid": "20998558", "title": "Remedial occupational therapy in an Army general hospital.", "content": "Remedial occupational therapy in an Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998558"}
{"pmid": "20998559", "title": "Occupational therapy; where, how, why?", "content": "Occupational therapy; where, how, why?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998559"}
{"pmid": "20998560", "title": "Psychological foundations of occupational therapy.", "content": "Psychological foundations of occupational therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998560"}
{"pmid": "20998547", "title": "Treatment of septic conditions which result in abscess.", "content": "Treatment of septic conditions which result in abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998547"}
{"pmid": "20998561", "title": "Occupational therapy in the New York City Home for Dependents.", "content": "Occupational therapy in the New York City Home for Dependents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998561"}
{"pmid": "20998562", "title": "Developments in treatment of the mentally ill.", "content": "Developments in treatment of the mentally ill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998562"}
{"pmid": "20998563", "title": "Occupational therapy for the psychotic patient.", "content": "Occupational therapy for the psychotic patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998563"}
{"pmid": "20998564", "title": "CLINICAL use of thrombin topical.", "content": "CLINICAL use of thrombin topical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998564"}
{"pmid": "20998565", "title": "PROTECTION against influenza.", "content": "PROTECTION against influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998565"}
{"pmid": "20998566", "title": "Antibiotic substances as therapeutic agents.", "content": "Antibiotic substances as therapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998566"}
{"pmid": "20998567", "title": "LIST of known antibiotic substances.", "content": "LIST of known antibiotic substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998567"}
{"pmid": "20998568", "title": "PENICILLIN-CHART.", "content": "PENICILLIN-CHART.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998568"}
{"pmid": "20998569", "title": "METHOD of preparing penicillin for treatment.", "content": "METHOD of preparing penicillin for treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998569"}
{"pmid": "20998570", "title": "LOCAL application of sulfonamide compounds.", "content": "LOCAL application of sulfonamide compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998570"}
{"pmid": "20998571", "title": "INHIBITOR of sulfanilamides.", "content": "INHIBITOR of sulfanilamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998571"}
{"pmid": "20998572", "title": "The significance of the free resp. substituted para amino group in the sulfanilamide molecule.", "content": "The significance of the free resp. substituted para amino group in the sulfanilamide molecule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998572"}
{"pmid": "20998573", "title": "Peptic ulcer and angina pectoris.", "content": "Peptic ulcer and angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998573"}
{"pmid": "20998574", "title": "Recent developments in cardiac glucoside research.", "content": "Recent developments in cardiac glucoside research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998574"}
{"pmid": "20998575", "title": "INTESTINAL synthesis of vitamins.", "content": "INTESTINAL synthesis of vitamins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998575"}
{"pmid": "20998576", "title": "B-vitamins and resistance to infection.", "content": "B-vitamins and resistance to infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998576"}
{"pmid": "20998577", "title": "Natural and synthetic female hormones in therapeutic use.", "content": "Natural and synthetic female hormones in therapeutic use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998577"}
{"pmid": "20998578", "title": "CLINICAL observations on enterosept made at the Government Hospital, Haifa.", "content": "CLINICAL observations on enterosept made at the Government Hospital, Haifa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998578"}
{"pmid": "20998579", "title": "DIFFERENTIAL characteristics of amoebae living in man.", "content": "DIFFERENTIAL characteristics of amoebae living in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998579"}
{"pmid": "20998580", "title": "PULMONARY anoebiasis.", "content": "PULMONARY anoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998580"}
{"pmid": "20998605", "title": "A simplified medium for cultivation of leishmania; longevity of cultures.", "content": "A simplified medium for cultivation of leishmania; longevity of cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998605"}
{"pmid": "20998604", "title": "Treatment of B. T. and M. T. malaria with paludrine; temperature charts and diagrams illustrating plasma and urinary concentration of paludrine.", "content": "Treatment of B. T. and M. T. malaria with paludrine; temperature charts and diagrams illustrating plasma and urinary concentration of paludrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998604"}
{"pmid": "20998606", "title": "The life-cycle and habits of British culicoides.", "content": "The life-cycle and habits of British culicoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998606"}
{"pmid": "20998607", "title": "A technique for maintaining Phlebotomus papatasil in this country.", "content": "A technique for maintaining Phlebotomus papatasil in this country.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998607"}
{"pmid": "20998608", "title": "Investigations on Liponyssus bacoti as a vector of Litomosoides carinii in cotton rats.", "content": "Investigations on Liponyssus bacoti as a vector of Litomosoides carinii in cotton rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998608"}
{"pmid": "20998609", "title": "Technique employed for obtaining bacteria-free suspensions of sporozoites of Plasmodium galliaceum.", "content": "Technique employed for obtaining bacteria-free suspensions of sporozoites of Plasmodium galliaceum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998609"}
{"pmid": "20998610", "title": "Observations on tsutsugamushi disease (scrub typhus) in Assam and Burma.", "content": "Observations on tsutsugamushi disease (scrub typhus) in Assam and Burma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998610"}
{"pmid": "20998611", "title": "The distribution of immunity to yellow fever in Central and East Africa.", "content": "The distribution of immunity to yellow fever in Central and East Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998611"}
{"pmid": "20998612", "title": "The incidence of sicklemia in West Africa.", "content": "The incidence of sicklemia in West Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998612"}
{"pmid": "20998613", "title": "Cooley's anaemia; notes on 6 adult cases.", "content": "Cooley's anaemia; notes on 6 adult cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998613"}
{"pmid": "20998614", "title": "Penicillin in the treatment of experimental relapsing fever in rats.", "content": "Penicillin in the treatment of experimental relapsing fever in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998614"}
{"pmid": "20998615", "title": "Collapse of the lung and porocephalosis.", "content": "Collapse of the lung and porocephalosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998615"}
{"pmid": "20998616", "title": "Minimal tuberculosis in the Negro; a study of Negro patients discharged from Robert Koch Hospital with minimal tuberculosis between 1927 and 1942.", "content": "Minimal tuberculosis in the Negro; a study of Negro patients discharged from Robert Koch Hospital with minimal tuberculosis between 1927 and 1942.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998616"}
{"pmid": "20998617", "title": "A simple and practical method of obtaining complete bronchograms.", "content": "A simple and practical method of obtaining complete bronchograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998617"}
{"pmid": "20998618", "title": "Bronchography in tuberculosis.", "content": "Bronchography in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998618"}
{"pmid": "20998619", "title": "Oleothorax; a reevaluation, with a final report of 101 cases.", "content": "Oleothorax; a reevaluation, with a final report of 101 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998619"}
{"pmid": "20998620", "title": "Dietaries in tuberculosis sanatoria; report of the approximate nutritional evaluation of 34 County tuberculosis hospital dietaries during 1943 and 1944.", "content": "Dietaries in tuberculosis sanatoria; report of the approximate nutritional evaluation of 34 County tuberculosis hospital dietaries during 1943 and 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998620"}
{"pmid": "20998622", "title": "Tuberculosis as an occupational hazard during medical training.", "content": "Tuberculosis as an occupational hazard during medical training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998622"}
{"pmid": "20998621", "title": "Tuberculous pleurisy with effusion.", "content": "Tuberculous pleurisy with effusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998621"}
{"pmid": "20998623", "title": "Tuberculin reactors; an interpretation and evaluation of certain data.", "content": "Tuberculin reactors; an interpretation and evaluation of certain data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998623"}
{"pmid": "20998624", "title": "Sarcoidosis.", "content": "Sarcoidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998624"}
{"pmid": "20998625", "title": "Retardants to the growth of tubercle bacilli; the effect of caramelization of growth.", "content": "Retardants to the growth of tubercle bacilli; the effect of caramelization of growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998625"}
{"pmid": "20998626", "title": "Tubercle endotoxoid (Grasset) in experimental tuberculosis in guinea pigs.", "content": "Tubercle endotoxoid (Grasset) in experimental tuberculosis in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998626"}
{"pmid": "20998631", "title": "Early and late results of extrapleural pneumothorax.", "content": "Early and late results of extrapleural pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998631"}
{"pmid": "20998632", "title": "The morbidity of pulmonary tuberculosis; statistical aspects.", "content": "The morbidity of pulmonary tuberculosis; statistical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998632"}
{"pmid": "20998633", "title": "SARCOIDOSIS.", "content": "SARCOIDOSIS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998633"}
{"pmid": "20998634", "title": "Epizoötiology of Newcastle disease of poultry.", "content": "Epizoötiology of Newcastle disease of poultry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998634"}
{"pmid": "20998635", "title": "The comparative pathology of fowl plague and Newcastle disease.", "content": "The comparative pathology of fowl plague and Newcastle disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998635"}
{"pmid": "20998641", "title": "Control of enterotoxemia (pulpy kidney disease) in lambs by the use of alum precipitated toxoid.", "content": "Control of enterotoxemia (pulpy kidney disease) in lambs by the use of alum precipitated toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998641"}
{"pmid": "20998637", "title": "Immunization of chickens against Newcastle disease.", "content": "Immunization of chickens against Newcastle disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998637"}
{"pmid": "20998638", "title": "Transmission of antiviral activity via the egg and the rôle of congenital passive immunity to Newcastle disease in chickens.", "content": "Transmission of antiviral activity via the egg and the rôle of congenital passive immunity to Newcastle disease in chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998638"}
{"pmid": "20998636", "title": "The isolation and identification of Newcastle disease virus.", "content": "The isolation and identification of Newcastle disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998636"}
{"pmid": "20998640", "title": "Treatment of filarial dermatosis of sheep with antimony compounds.", "content": "Treatment of filarial dermatosis of sheep with antimony compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998640"}
{"pmid": "20998643", "title": "The relative activity of sulfanilamides and other compounds in avian coccidiosis (Eimeria tenella).", "content": "The relative activity of sulfanilamides and other compounds in avian coccidiosis (Eimeria tenella).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998643"}
{"pmid": "20998642", "title": "Hexachlorethane-bentonite suspension for the removal of the common liver fluke, Fasciola hepatica, from sheep.", "content": "Hexachlorethane-bentonite suspension for the removal of the common liver fluke, Fasciola hepatica, from sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998642"}
{"pmid": "20998644", "title": "Studies on the toxicity of DDT for domestic and laboratory animals.", "content": "Studies on the toxicity of DDT for domestic and laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998644"}
{"pmid": "20998639", "title": "The tonsils of the horse.", "content": "The tonsils of the horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998639"}
{"pmid": "20998645", "title": "The effect of sunlight on the initiation of sexual activity in ranch mink.", "content": "The effect of sunlight on the initiation of sexual activity in ranch mink.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998645"}
{"pmid": "20998646", "title": "Studies on pullorum disease using various rapid antigens.", "content": "Studies on pullorum disease using various rapid antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998646"}
{"pmid": "20998647", "title": "Lentin in veterinary medicine; a review.", "content": "Lentin in veterinary medicine; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998647"}
{"pmid": "20998648", "title": "Urinary calculi.", "content": "Urinary calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998648"}
{"pmid": "20998649", "title": "Systemic blastomycosis in dogs.", "content": "Systemic blastomycosis in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998649"}
{"pmid": "20998650", "title": "Quick protection and therapeutic effect of distemperoid virus.", "content": "Quick protection and therapeutic effect of distemperoid virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998650"}
{"pmid": "20998651", "title": "Reports on the use of DDT in the form of deenols in canine practice.", "content": "Reports on the use of DDT in the form of deenols in canine practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998651"}
{"pmid": "20998652", "title": "Salmonella bareilly in quail.", "content": "Salmonella bareilly in quail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998652"}
{"pmid": "20998653", "title": "Ethics in the practice of veterinary medicine.", "content": "Ethics in the practice of veterinary medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998653"}
{"pmid": "20998654", "title": "Some aspects of the pharmacology of the sulfonamides and penicillin.", "content": "Some aspects of the pharmacology of the sulfonamides and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998654"}
{"pmid": "20998655", "title": "Mastitis and the practitioner.", "content": "Mastitis and the practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998655"}
{"pmid": "20998657", "title": "INFECTIOUS equine encephalomyelitis in the United States in 1945.", "content": "INFECTIOUS equine encephalomyelitis in the United States in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998657"}
{"pmid": "20998656", "title": "Ectasia of the esophagus.", "content": "Ectasia of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998656"}
{"pmid": "20998658", "title": "Reconversion planning, with special emphasis on personnel.", "content": "Reconversion planning, with special emphasis on personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998658"}
{"pmid": "20998662", "title": "Bleeding cattle for brucellosis testing.", "content": "Bleeding cattle for brucellosis testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998662"}
{"pmid": "20998663", "title": "Cystic hemangiofibroma of the spleen with accessory spleen.", "content": "Cystic hemangiofibroma of the spleen with accessory spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998663"}
{"pmid": "20998664", "title": "Bartonella infection in a dog.", "content": "Bartonella infection in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998664"}
{"pmid": "20998660", "title": "Artificial insemination.", "content": "Artificial insemination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998660"}
{"pmid": "20998659", "title": "Some aspects of the pharmacology of DDT.", "content": "Some aspects of the pharmacology of DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998659"}
{"pmid": "20998661", "title": "Bovine mastitis caused by Pasteurellae.", "content": "Bovine mastitis caused by Pasteurellae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998661"}
{"pmid": "20998665", "title": "Vesical calculi in a puppy.", "content": "Vesical calculi in a puppy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998665"}
{"pmid": "20998681", "title": "Toxicity of alpha naphthyl thiourea for chickens and pigs.", "content": "Toxicity of alpha naphthyl thiourea for chickens and pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998681"}
{"pmid": "20998682", "title": "SWINE brucellosis control program.", "content": "SWINE brucellosis control program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998682"}
{"pmid": "20998683", "title": "Lead arsenate relieves scouring in lambs due to tapeworm infestation.", "content": "Lead arsenate relieves scouring in lambs due to tapeworm infestation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998683"}
{"pmid": "20998684", "title": "The incidence of setariasis in Colombia.", "content": "The incidence of setariasis in Colombia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998684"}
{"pmid": "20998685", "title": "Parasites and parasitic diseases of swine.", "content": "Parasites and parasitic diseases of swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998685"}
{"pmid": "20998686", "title": "Common diseases of the domestic rabbit.", "content": "Common diseases of the domestic rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998686"}
{"pmid": "20998687", "title": "Abscess and furunculosis in a dog.", "content": "Abscess and furunculosis in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998687"}
{"pmid": "20998688", "title": "Hordeum pusillum heads injure dog.", "content": "Hordeum pusillum heads injure dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998688"}
{"pmid": "20998689", "title": "Milk in the treatment of keratitis.", "content": "Milk in the treatment of keratitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998689"}
{"pmid": "20998690", "title": "Diaphragmatic hernia.", "content": "Diaphragmatic hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998690"}
{"pmid": "20998691", "title": "Research on dog foods and dog feeding.", "content": "Research on dog foods and dog feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998691"}
{"pmid": "20998692", "title": "Preliminary report on the propagation of hog cholera virus in vitro.", "content": "Preliminary report on the propagation of hog cholera virus in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998692"}
{"pmid": "20998693", "title": "Army food inspection in the China-Burma-India Theater.", "content": "Army food inspection in the China-Burma-India Theater.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998693"}
{"pmid": "20998694", "title": "The use of DDT in medicine; a review.", "content": "The use of DDT in medicine; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998694"}
{"pmid": "20998695", "title": "Toxicity of sodium chloride solution for baby chicks.", "content": "Toxicity of sodium chloride solution for baby chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998695"}
{"pmid": "20998696", "title": "Internal parasites in five-week old Great Dane pups.", "content": "Internal parasites in five-week old Great Dane pups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998696"}
{"pmid": "20998697", "title": "Vicious union of a fractured tibia in a deer.", "content": "Vicious union of a fractured tibia in a deer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998697"}
{"pmid": "20998698", "title": "Lipoma in a pig.", "content": "Lipoma in a pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998698"}
{"pmid": "20998699", "title": "Bovine auto-amputation.", "content": "Bovine auto-amputation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998699"}
{"pmid": "20998700", "title": "Breeding efficiency lowered following anaplasmosis.", "content": "Breeding efficiency lowered following anaplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998700"}
{"pmid": "20998701", "title": "The diagnostic value of the blood leucocyte picture in traumatic reticulitis and pericarditis of bovines.", "content": "The diagnostic value of the blood leucocyte picture in traumatic reticulitis and pericarditis of bovines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998701"}
{"pmid": "20998702", "title": "The control of enterotoxaemia in fattening sheep by a single inoculation with C1. welchii, Type D, anaculture.", "content": "The control of enterotoxaemia in fattening sheep by a single inoculation with C1. welchii, Type D, anaculture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998702"}
{"pmid": "20998703", "title": "A charter for milk production.", "content": "A charter for milk production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998703"}
{"pmid": "20998704", "title": "Equine castration; two unusual occurrences.", "content": "Equine castration; two unusual occurrences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998704"}
{"pmid": "20998706", "title": "Tuberculosis of the supramammary glands.", "content": "Tuberculosis of the supramammary glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998706"}
{"pmid": "20998705", "title": "Reminiscences of the courts.", "content": "Reminiscences of the courts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998705"}
{"pmid": "20998707", "title": "The clinical laboratory and the practitioner.", "content": "The clinical laboratory and the practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998707"}
{"pmid": "20998708", "title": "A note on the toxicity of phenanthridinium 1553 for cattle.", "content": "A note on the toxicity of phenanthridinium 1553 for cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998708"}
{"pmid": "20998709", "title": "Wound treatment in small-animal practice.", "content": "Wound treatment in small-animal practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998709"}
{"pmid": "20998710", "title": "Flock idiosyncrasy to carbon tetrachloride.", "content": "Flock idiosyncrasy to carbon tetrachloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998710"}
{"pmid": "20998712", "title": "The tegumental glands in the land Isopoda; the rosette glands.", "content": "The tegumental glands in the land Isopoda; the rosette glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998712"}
{"pmid": "20998711", "title": "Cytochemical differentiation between the pentose and desoxypentose nucleic acids in tissue sections.", "content": "Cytochemical differentiation between the pentose and desoxypentose nucleic acids in tissue sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998711"}
{"pmid": "20998713", "title": "The chondrocranium of Calotes versicolor (Daud.) with a description of the osteocranium of a just-hatched young.", "content": "The chondrocranium of Calotes versicolor (Daud.) with a description of the osteocranium of a just-hatched young.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998713"}
{"pmid": "20998714", "title": "The development of the olfactory organ of Kaloula borealis (Barbour) as compared with that of Rana nigromaculata Hallowell.", "content": "The development of the olfactory organ of Kaloula borealis (Barbour) as compared with that of Rana nigromaculata Hallowell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998714"}
{"pmid": "20998715", "title": "Brucella suis in aerated broth culture; preliminary studies on growth assays, inoculum, and growth characteristics in an improved medium.", "content": "Brucella suis in aerated broth culture; preliminary studies on growth assays, inoculum, and growth characteristics in an improved medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998715"}
{"pmid": "20998716", "title": "Brucella suis in aerated broth culture; aeration studies.", "content": "Brucella suis in aerated broth culture; aeration studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998716"}
{"pmid": "20998717", "title": "Brucella suis in aerated broth culture; continuous culture studies.", "content": "Brucella suis in aerated broth culture; continuous culture studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998717"}
{"pmid": "20998718", "title": "A critical evaluation of the nitrogen assimilation tests commonly used in the classification of yeasts.", "content": "A critical evaluation of the nitrogen assimilation tests commonly used in the classification of yeasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998718"}
{"pmid": "20998719", "title": "A new medium for the detection of urea-splitting organisms.", "content": "A new medium for the detection of urea-splitting organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998719"}
{"pmid": "20998720", "title": "False positive hemoagglutination by allantoic fluids of embryonated eggs inoculated with unfiltered throat washings.", "content": "False positive hemoagglutination by allantoic fluids of embryonated eggs inoculated with unfiltered throat washings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998720"}
{"pmid": "20998721", "title": "Decomposition of tartrates by the coliform bacteria.", "content": "Decomposition of tartrates by the coliform bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998721"}
{"pmid": "20998722", "title": "Methods of study of antiphage agents produced by microorganisms.", "content": "Methods of study of antiphage agents produced by microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998722"}
{"pmid": "20998723", "title": "Temperature relations in phagocytosis.", "content": "Temperature relations in phagocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998723"}
{"pmid": "20998724", "title": "Salmonella senegal, a new type isolated from a green mamba snake.", "content": "Salmonella senegal, a new type isolated from a green mamba snake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998724"}
{"pmid": "20998725", "title": "The effect of aeration of amylase production by Bacillus macerans.", "content": "The effect of aeration of amylase production by Bacillus macerans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998725"}
{"pmid": "20998726", "title": "Acetic acid inhibition of gram-negative bacilli in culture media.", "content": "Acetic acid inhibition of gram-negative bacilli in culture media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998726"}
{"pmid": "20998727", "title": "Studies on the production of antibiotics by actinomycetes and molds.", "content": "Studies on the production of antibiotics by actinomycetes and molds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998727"}
{"pmid": "20998728", "title": "The use of soluble starch medium in the preparation of smooth 0 Salmonella antigens.", "content": "The use of soluble starch medium in the preparation of smooth 0 Salmonella antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998728"}
{"pmid": "20998729", "title": "A method for the aseptic handling of highly viscous materials.", "content": "A method for the aseptic handling of highly viscous materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998729"}
{"pmid": "20998732", "title": "Isolation of streptomycin-producing strains of Streptomyces griseus.", "content": "Isolation of streptomycin-producing strains of Streptomyces griseus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998732"}
{"pmid": "20998731", "title": "The fragmentation of the mycelium of Penicillium notatum and Penicillium chrysogenum by a high-speed blender and the evaluation of blended seed.", "content": "The fragmentation of the mycelium of Penicillium notatum and Penicillium chrysogenum by a high-speed blender and the evaluation of blended seed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998731"}
{"pmid": "20998730", "title": "Bacterial lysis by lysozyme.", "content": "Bacterial lysis by lysozyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998730"}
{"pmid": "20998733", "title": "Limits of effectiveness of streptomycin in arthritis of rats.", "content": "Limits of effectiveness of streptomycin in arthritis of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998733"}
{"pmid": "20998734", "title": "The air wave surrounding an expanding sphere.", "content": "The air wave surrounding an expanding sphere.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998734"}
{"pmid": "20998735", "title": "Explosion waves and shock waves; the disturbance produced by bursting diaphragms with compressed air.", "content": "Explosion waves and shock waves; the disturbance produced by bursting diaphragms with compressed air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998735"}
{"pmid": "20998736", "title": "The diffraction of sound pulses; diffraction by a semi-infinite plane.", "content": "The diffraction of sound pulses; diffraction by a semi-infinite plane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998736"}
{"pmid": "20998737", "title": "The diffraction of sound pulses; diffraction by an infinite wedge.", "content": "The diffraction of sound pulses; diffraction by an infinite wedge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998737"}
{"pmid": "20998738", "title": "The diffraction of sound pulses; note on an integral occurring in the theory of diffraction by a semi-infinite screen.", "content": "The diffraction of sound pulses; note on an integral occurring in the theory of diffraction by a semi-infinite screen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998738"}
{"pmid": "20998739", "title": "The diffraction of sound pulses; on a paradox in the theory of reflexion.", "content": "The diffraction of sound pulses; on a paradox in the theory of reflexion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998739"}
{"pmid": "20998740", "title": "The rate of evaporation of droplets; evaporation and diffusion coefficients, and vapour pressures of dibutyl phthalate and butyl stearate.", "content": "The rate of evaporation of droplets; evaporation and diffusion coefficients, and vapour pressures of dibutyl phthalate and butyl stearate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998740"}
{"pmid": "20998741", "title": "An invariant form for the prior probability in estimation problems.", "content": "An invariant form for the prior probability in estimation problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998741"}
{"pmid": "20998742", "title": "The mechanism of the hydrogen-oxygen reaction; the activation energy of the initiating process.", "content": "The mechanism of the hydrogen-oxygen reaction; the activation energy of the initiating process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998742"}
{"pmid": "20998743", "title": "The mechanism of the hydrogen-oxygen reaction; the reaction in vessels coated with alkali iodides.", "content": "The mechanism of the hydrogen-oxygen reaction; the reaction in vessels coated with alkali iodides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998743"}
{"pmid": "20998744", "title": "Sclerosing treatment for subluxation of the temporomandibular joint.", "content": "Sclerosing treatment for subluxation of the temporomandibular joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998744"}
{"pmid": "20998745", "title": "The efficiency of the Russell attachment.", "content": "The efficiency of the Russell attachment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998745"}
{"pmid": "20998746", "title": "The value of model experiments on tooth movement.", "content": "The value of model experiments on tooth movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998746"}
{"pmid": "20998747", "title": "Simplified technique for soldering intermaxillary hooks or stops on small chrome alloy arches without reducing temper of the arch.", "content": "Simplified technique for soldering intermaxillary hooks or stops on small chrome alloy arches without reducing temper of the arch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998747"}
{"pmid": "20998748", "title": "The 6th General Hospital (Massachusetts General Hospital Unit).", "content": "The 6th General Hospital (Massachusetts General Hospital Unit).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998748"}
{"pmid": "20998750", "title": "Surgical correction of mandibular prognathism in two edentulous patients.", "content": "Surgical correction of mandibular prognathism in two edentulous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998750"}
{"pmid": "20998749", "title": "Observations on 200 jaw fracture cases admitted to the 6th General Hospital.", "content": "Observations on 200 jaw fracture cases admitted to the 6th General Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998749"}
{"pmid": "20998751", "title": "Case report of adenoadamantoblastoma.", "content": "Case report of adenoadamantoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998751"}
{"pmid": "20998752", "title": "Case report of reconstruction of lip, chin, and mandibular symphysis.", "content": "Case report of reconstruction of lip, chin, and mandibular symphysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998752"}
{"pmid": "20998753", "title": "Impressions with alginate materials.", "content": "Impressions with alginate materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998753"}
{"pmid": "20998754", "title": "Health and posture of the dentist.", "content": "Health and posture of the dentist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998754"}
{"pmid": "20998755", "title": "Rationale of treatment in maxillofacial injuries with report of four cases.", "content": "Rationale of treatment in maxillofacial injuries with report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998755"}
{"pmid": "20998756", "title": "Use of penicillin in the treatment of Vincent's infection and its subsequent oral disturbances.", "content": "Use of penicillin in the treatment of Vincent's infection and its subsequent oral disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998756"}
{"pmid": "20998757", "title": "Recent review and discussion of penicillin.", "content": "Recent review and discussion of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998757"}
{"pmid": "20998758", "title": "Compound composite odontoma of the mandible.", "content": "Compound composite odontoma of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998758"}
{"pmid": "20998761", "title": "Ranula.", "content": "Ranula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998761"}
{"pmid": "20998760", "title": "Stabilization of fragments of an edentulous mandible showing extensive loss of bone.", "content": "Stabilization of fragments of an edentulous mandible showing extensive loss of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998760"}
{"pmid": "20998759", "title": "Intra-oral surgical reduction of the mandible after failure to correct the displacement by elastic traction.", "content": "Intra-oral surgical reduction of the mandible after failure to correct the displacement by elastic traction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998759"}
{"pmid": "20998762", "title": "Presence of glycosuria in deep post-operative submandibular cellulitis.", "content": "Presence of glycosuria in deep post-operative submandibular cellulitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998762"}
{"pmid": "20998763", "title": "Fatal tetanus associated with acute maxillary sinusitis.", "content": "Fatal tetanus associated with acute maxillary sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998763"}
{"pmid": "20998764", "title": "Bilateral osteotomy for retrusion of the mandible.", "content": "Bilateral osteotomy for retrusion of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998764"}
{"pmid": "20998766", "title": "Reduction and immobilization of fracture of the maxilla by internal wire suspension.", "content": "Reduction and immobilization of fracture of the maxilla by internal wire suspension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998766"}
{"pmid": "20998765", "title": "Osteomyelitis of the mandible.", "content": "Osteomyelitis of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998765"}
{"pmid": "20998767", "title": "Open reduction of fracture of the mandible.", "content": "Open reduction of fracture of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998767"}
{"pmid": "20998768", "title": "Hemiresection of the mandible for ossifying fibroma.", "content": "Hemiresection of the mandible for ossifying fibroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998768"}
{"pmid": "20998769", "title": "Preparation of a screw lock sectional splint with mechanical retention.", "content": "Preparation of a screw lock sectional splint with mechanical retention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998769"}
{"pmid": "20998780", "title": "STORY of blood plasma in the U.S.A.", "content": "STORY of blood plasma in the U.S.A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998780"}
{"pmid": "20998779", "title": "CHILD gives blood to baby brother.", "content": "CHILD gives blood to baby brother.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998779"}
{"pmid": "20998783", "title": "Medical practice in Illinois before hard roads.", "content": "Medical practice in Illinois before hard roads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998783"}
{"pmid": "20998782", "title": "A prelude to medical history.", "content": "A prelude to medical history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998782"}
{"pmid": "20998784", "title": "Medical zoology in America's fir century.", "content": "Medical zoology in America's fir century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998784"}
{"pmid": "20998781", "title": "Hippocrates and the Isle of Cos.", "content": "Hippocrates and the Isle of Cos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998781"}
{"pmid": "20998785", "title": "Shoe wedging.", "content": "Shoe wedging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998785"}
{"pmid": "20998786", "title": "Early pathogenesis following vertebral strain.", "content": "Early pathogenesis following vertebral strain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998786"}
{"pmid": "20998787", "title": "Osteopathic education looks ahead.", "content": "Osteopathic education looks ahead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998787"}
{"pmid": "20998788", "title": "New York's war on disease.", "content": "New York's war on disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998788"}
{"pmid": "20998789", "title": "Recent advances in medicine.", "content": "Recent advances in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998789"}
{"pmid": "20998790", "title": "Osteopathy and the war on human suffering.", "content": "Osteopathy and the war on human suffering.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998790"}
{"pmid": "20998791", "title": "Osteopathy; a youthful profession.", "content": "Osteopathy; a youthful profession.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998791"}
{"pmid": "20998793", "title": "HOME accidents; tragedies that can be prevented.", "content": "HOME accidents; tragedies that can be prevented.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998793"}
{"pmid": "20998792", "title": "American Surgical Centre, Queen Victoria Hospital, East Grinstead; the most specialised and up to date in the United Kingdom.", "content": "American Surgical Centre, Queen Victoria Hospital, East Grinstead; the most specialised and up to date in the United Kingdom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998792"}
{"pmid": "20998794", "title": "The hospital administrator and the X-ray department; how to avoid inefficiency and waste.", "content": "The hospital administrator and the X-ray department; how to avoid inefficiency and waste.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998794"}
{"pmid": "20998795", "title": "The medical and hospital activities of the Veterans Administration.", "content": "The medical and hospital activities of the Veterans Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998795"}
{"pmid": "20998796", "title": "The voluntary hospital and the care of veterans.", "content": "The voluntary hospital and the care of veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998796"}
{"pmid": "20998797", "title": "The adaptation of nursing education to the nursing needs of the nation.", "content": "The adaptation of nursing education to the nursing needs of the nation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998797"}
{"pmid": "20998798", "title": "The personnel policy for general duty nurses.", "content": "The personnel policy for general duty nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998798"}
{"pmid": "20998799", "title": "Education for the health professions.", "content": "Education for the health professions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998799"}
{"pmid": "20998800", "title": "Procedures for the intern recruitment programs as devised by the Association of American Medical Colleges.", "content": "Procedures for the intern recruitment programs as devised by the Association of American Medical Colleges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998800"}
{"pmid": "20998801", "title": "The relation between the growth of nutrition and the science of dietetics.", "content": "The relation between the growth of nutrition and the science of dietetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998801"}
{"pmid": "20998802", "title": "High protein diet.", "content": "High protein diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998802"}
{"pmid": "20998803", "title": "The neutral diet.", "content": "The neutral diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998803"}
{"pmid": "20998804", "title": "A pension program and its relation to hospital personnel.", "content": "A pension program and its relation to hospital personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998804"}
{"pmid": "20998805", "title": "The hospital survey as an aid in institutional education and planning.", "content": "The hospital survey as an aid in institutional education and planning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998805"}
{"pmid": "20998806", "title": "The collection and centralization of statistics.", "content": "The collection and centralization of statistics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998806"}
{"pmid": "20998807", "title": "Principles of organization and administration.", "content": "Principles of organization and administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998807"}
{"pmid": "20998808", "title": "Cotton's future in the hospital.", "content": "Cotton's future in the hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998808"}
{"pmid": "20998809", "title": "Accounting in the development of hospital rates.", "content": "Accounting in the development of hospital rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998809"}
{"pmid": "20998810", "title": "The nursing care of psychiatric patients.", "content": "The nursing care of psychiatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998810"}
{"pmid": "20998812", "title": "Preparation of parenteral medications.", "content": "Preparation of parenteral medications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998812"}
{"pmid": "20998811", "title": "The teaching responsibilities of the dietitian.", "content": "The teaching responsibilities of the dietitian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998811"}
{"pmid": "20998813", "title": "The need of psychiatric nursing in a general hospital.", "content": "The need of psychiatric nursing in a general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998813"}
{"pmid": "20998814", "title": "On increasing the yield and potency of typhus vaccine prepared from infected yolk sacs.", "content": "On increasing the yield and potency of typhus vaccine prepared from infected yolk sacs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998814"}
{"pmid": "20998815", "title": "Allergenic and anaphylactogenic properties of vaccines prepared from embryonic tissues of developing chicks.", "content": "Allergenic and anaphylactogenic properties of vaccines prepared from embryonic tissues of developing chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998815"}
{"pmid": "20998817", "title": "Allergenic and anaphylactogenic properties of vaccines prepared from embryonic tissues of developing chicks; a study to determine whether chick-embryo yolk-sac vaccines contain sufficient egg proteins to cause severe systemic reactions if given to egg-sensitive individuals.", "content": "Allergenic and anaphylactogenic properties of vaccines prepared from embryonic tissues of developing chicks; a study to determine whether chick-embryo yolk-sac vaccines contain sufficient egg proteins to cause severe systemic reactions if given to egg-sensitive individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998817"}
{"pmid": "20998820", "title": "Chemotherapy of experimental anthrax infections.", "content": "Chemotherapy of experimental anthrax infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998820"}
{"pmid": "20998816", "title": "Allergenic and anaphylactogenic properties of vaccines prepared from embryonic tissues of developing chicks; anaphylactogenic properties of typhus fever vaccines and equine encephalomyelitic vaccines.", "content": "Allergenic and anaphylactogenic properties of vaccines prepared from embryonic tissues of developing chicks; anaphylactogenic properties of typhus fever vaccines and equine encephalomyelitic vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998816"}
{"pmid": "20998819", "title": "Endotoxic factors of Rickettsia prowazeki and their immunological relationship to the endotoxins of other gram-negative microorganisms.", "content": "Endotoxic factors of Rickettsia prowazeki and their immunological relationship to the endotoxins of other gram-negative microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998819"}
{"pmid": "20998818", "title": "Studies on the physiology of anaphylactic shock; the reactivity of the isolated rat intestine to antigen, to histamine, and to acetylcholine.", "content": "Studies on the physiology of anaphylactic shock; the reactivity of the isolated rat intestine to antigen, to histamine, and to acetylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998818"}
{"pmid": "20998821", "title": "Immunologic studies in rheumatic fever; antistreptolysin patterns in rheumatic children.", "content": "Immunologic studies in rheumatic fever; antistreptolysin patterns in rheumatic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998821"}
{"pmid": "20998823", "title": "Studies on the chemotherapy of viruses in the psittacosislymphogranuloma group.", "content": "Studies on the chemotherapy of viruses in the psittacosislymphogranuloma group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998823"}
{"pmid": "20998822", "title": "Studies on ragweed pollen sensitization in rabbits and guinea pigs.", "content": "Studies on ragweed pollen sensitization in rabbits and guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998822"}
{"pmid": "20998825", "title": "A heterologous principle in human cancerous liver; its effect upon the Brown-Pearce tumor.", "content": "A heterologous principle in human cancerous liver; its effect upon the Brown-Pearce tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998825"}
{"pmid": "20998824", "title": "Studies on the chemotherapy of viruses in the psittacosis-lymphogranuloma group; effect of penicillin and sulfadiazine on seven strains in mice.", "content": "Studies on the chemotherapy of viruses in the psittacosis-lymphogranuloma group; effect of penicillin and sulfadiazine on seven strains in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998824"}
{"pmid": "20998826", "title": "Psittacosis vaccines prepared from chick embryo tissues.", "content": "Psittacosis vaccines prepared from chick embryo tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998826"}
{"pmid": "20998827", "title": "The role of antibodies in experimental drug resistance of Trypanosoma equiperdum.", "content": "The role of antibodies in experimental drug resistance of Trypanosoma equiperdum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998827"}
{"pmid": "20998828", "title": "Isolation of the virus of lymphogranuloma venereum from twenty-eight patients; relative value of the use of chick embryos and mice.", "content": "Isolation of the virus of lymphogranuloma venereum from twenty-eight patients; relative value of the use of chick embryos and mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998828"}
{"pmid": "20998829", "title": "The applicability of skin tests for sulfonamide hypersensitivity in children.", "content": "The applicability of skin tests for sulfonamide hypersensitivity in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998829"}
{"pmid": "20998830", "title": "Salmonella infections in the U.S.A.; a second series of 2,000 human infections recorded by the N.Y. Salmonella Center.", "content": "Salmonella infections in the U.S.A.; a second series of 2,000 human infections recorded by the N.Y. Salmonella Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998830"}
{"pmid": "20998831", "title": "Studies in human malaria; complement-fixation reactions.", "content": "Studies in human malaria; complement-fixation reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998831"}
{"pmid": "20998834", "title": "Coarctation of aorta.", "content": "Coarctation of aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998834"}
{"pmid": "20998833", "title": "The management of pyogenic meningitis in infants and children.", "content": "The management of pyogenic meningitis in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998833"}
{"pmid": "20998832", "title": "Use of yolk sac antigens for skin tests in rabbits infected with the virus of meningopneumonitis.", "content": "Use of yolk sac antigens for skin tests in rabbits infected with the virus of meningopneumonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998832"}
{"pmid": "20998835", "title": "Studies on the effect of diluting fluids on serological titres; a comparison of normal saline, 2.5% saline and pooled negative sera as diluting agents.", "content": "Studies on the effect of diluting fluids on serological titres; a comparison of normal saline, 2.5% saline and pooled negative sera as diluting agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998835"}
{"pmid": "20998836", "title": "D.H.E. 45 (dihydroergotamine) a new drug in the treatment of migraine.", "content": "D.H.E. 45 (dihydroergotamine) a new drug in the treatment of migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998836"}
{"pmid": "20998837", "title": "Some vulgar errors in regard to goitre.", "content": "Some vulgar errors in regard to goitre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998837"}
{"pmid": "20998839", "title": "Perforation of the ileum in enteric fever.", "content": "Perforation of the ileum in enteric fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998839"}
{"pmid": "20998838", "title": "Asthma in childhood.", "content": "Asthma in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998838"}
{"pmid": "20998840", "title": "Amoebiasis in Italy.", "content": "Amoebiasis in Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998840"}
{"pmid": "20998841", "title": "A case of hydatidiform mole at age 52.", "content": "A case of hydatidiform mole at age 52.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998841"}
{"pmid": "20998842", "title": "An unusual complication of thiouracil therapy.", "content": "An unusual complication of thiouracil therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998842"}
{"pmid": "20998843", "title": "A container for the culture of gonococci in carbon dioxide.", "content": "A container for the culture of gonococci in carbon dioxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998843"}
{"pmid": "20998844", "title": "Conditions desirable for the rapid progress of gerontological research.", "content": "Conditions desirable for the rapid progress of gerontological research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998844"}
{"pmid": "20998845", "title": "Highlights of the official public health history of Cleveland.", "content": "Highlights of the official public health history of Cleveland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998845"}
{"pmid": "20998846", "title": "Assessment of the working capacity of the physically disabled person.", "content": "Assessment of the working capacity of the physically disabled person.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998846"}
{"pmid": "20998847", "title": "Anaesthesia in the plastic surgery unit Canadian Army overseas.", "content": "Anaesthesia in the plastic surgery unit Canadian Army overseas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998847"}
{"pmid": "20998848", "title": "Anaesthetic experiences in 504 urological operations.", "content": "Anaesthetic experiences in 504 urological operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998848"}
{"pmid": "20998849", "title": "The contributions of Chinese medicine.", "content": "The contributions of Chinese medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998849"}
{"pmid": "20998850", "title": "Anaesthesia in upper abdominal surgery.", "content": "Anaesthesia in upper abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998850"}
{"pmid": "20998851", "title": "Anaesthesia in obstetrics.", "content": "Anaesthesia in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998851"}
{"pmid": "20998852", "title": "Increase in age group in tuberculosis.", "content": "Increase in age group in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998852"}
{"pmid": "20998856", "title": "Nursing activities.", "content": "Nursing activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998856"}
{"pmid": "20998853", "title": "An integrated approach to cerebral palsy.", "content": "An integrated approach to cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998853"}
{"pmid": "20998855", "title": "Child health; the brightest chapter.", "content": "Child health; the brightest chapter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998855"}
{"pmid": "20998859", "title": "MEDICAL education in Glasgow.", "content": "MEDICAL education in Glasgow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998859"}
{"pmid": "20998860", "title": "UNIVERSITY of Glasgow.", "content": "UNIVERSITY of Glasgow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998860"}
{"pmid": "20998854", "title": "Rehabilitation of speech for crippled children.", "content": "Rehabilitation of speech for crippled children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998854"}
{"pmid": "20998861", "title": "ROYAL Faculty of Physicians and Surgeons.", "content": "ROYAL Faculty of Physicians and Surgeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998861"}
{"pmid": "20998862", "title": "POST-GRADUATE medical education in Scotland.", "content": "POST-GRADUATE medical education in Scotland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998862"}
{"pmid": "20998863", "title": "GLASGOW Post-Graduate Medical Association.", "content": "GLASGOW Post-Graduate Medical Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998863"}
{"pmid": "20998864", "title": "GLASGOW Royal Infirmary.", "content": "GLASGOW Royal Infirmary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998864"}
{"pmid": "20998865", "title": "VICTORIA Infirmary.", "content": "VICTORIA Infirmary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998865"}
{"pmid": "20998867", "title": "SOUTHERN General Hospital.", "content": "SOUTHERN General Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998867"}
{"pmid": "20998866", "title": "STOBHILL Hospital.", "content": "STOBHILL Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998866"}
{"pmid": "20998868", "title": "War and disease.", "content": "War and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998868"}
{"pmid": "20998872", "title": "Recovery from primary Friedlander pneumonia (type B) on therapy with sulfadiazine and penicillin.", "content": "Recovery from primary Friedlander pneumonia (type B) on therapy with sulfadiazine and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998872"}
{"pmid": "20998869", "title": "Vitallium plates used in repair of large hernias.", "content": "Vitallium plates used in repair of large hernias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998869"}
{"pmid": "20998870", "title": "Recent developments in the treatment of hypertension.", "content": "Recent developments in the treatment of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998870"}
{"pmid": "20998871", "title": "Treatment of fractures of superior and inferior maxilla.", "content": "Treatment of fractures of superior and inferior maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998871"}
{"pmid": "20998873", "title": "A Rorschach study of symptomatic schizophrenia following brain trauma.", "content": "A Rorschach study of symptomatic schizophrenia following brain trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998873"}
{"pmid": "20998857", "title": "A sanitary needs survey of Delaware.", "content": "A sanitary needs survey of Delaware.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998857"}
{"pmid": "20998874", "title": "Human ornithosis.", "content": "Human ornithosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998874"}
{"pmid": "20998875", "title": "Report of the Rotunda Hospital.", "content": "Report of the Rotunda Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998875"}
{"pmid": "20998876", "title": "Clinical report of the Coombe Lying-in Hospital.", "content": "Clinical report of the Coombe Lying-in Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998876"}
{"pmid": "20998877", "title": "Clinical report of the National Maternity Hospital.", "content": "Clinical report of the National Maternity Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998877"}
{"pmid": "20998878", "title": "Treatment of sacroiliac sprain by manipulation.", "content": "Treatment of sacroiliac sprain by manipulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998878"}
{"pmid": "20998858", "title": "Medical treatment of high blood pressure.", "content": "Medical treatment of high blood pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998858"}
{"pmid": "20998879", "title": "A history of medicine in Duval County.", "content": "A history of medicine in Duval County.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998879"}
{"pmid": "20998880", "title": "Litigation of the inferior vena cava as a therapeutic procedure.", "content": "Litigation of the inferior vena cava as a therapeutic procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998880"}
{"pmid": "20998886", "title": "A rare case of collective food poisoning.", "content": "A rare case of collective food poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998886"}
{"pmid": "20998896", "title": "He looked in the liver [President's address].", "content": "He looked in the liver [President's address].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998896"}
{"pmid": "20998897", "title": "Agranulocytosis following thiouracil therapy.", "content": "Agranulocytosis following thiouracil therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998897"}
{"pmid": "20998898", "title": "Endometriosis.", "content": "Endometriosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998898"}
{"pmid": "20998899", "title": "Occupational skin diseases in the steel industry.", "content": "Occupational skin diseases in the steel industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998899"}
{"pmid": "20998900", "title": "Streptomycin in Hemophilus influenzae meningitis.", "content": "Streptomycin in Hemophilus influenzae meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998900"}
{"pmid": "20998902", "title": "Penicillin in wound exudates.", "content": "Penicillin in wound exudates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998902"}
{"pmid": "20998901", "title": "Tropical skin diseases with practical references to civilian application.", "content": "Tropical skin diseases with practical references to civilian application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998901"}
{"pmid": "20998903", "title": "Coronary occlusion in young adults; review of 50 cases in the services.", "content": "Coronary occlusion in young adults; review of 50 cases in the services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998903"}
{"pmid": "20998904", "title": "Deficiency diseases in prisoners of war at Changi, Singapore, February 1942 to August 1945.", "content": "Deficiency diseases in prisoners of war at Changi, Singapore, February 1942 to August 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998904"}
{"pmid": "20998905", "title": "Blood-groups in bone marrow.", "content": "Blood-groups in bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998905"}
{"pmid": "20998906", "title": "Pneumoperitoneum-refill needle.", "content": "Pneumoperitoneum-refill needle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998906"}
{"pmid": "20998907", "title": "Health education; its problems and methods.", "content": "Health education; its problems and methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998907"}
{"pmid": "20998908", "title": "A visit to Finland.", "content": "A visit to Finland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998908"}
{"pmid": "20998909", "title": "B.C.G.; the next phase.", "content": "B.C.G.; the next phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998909"}
{"pmid": "20998910", "title": "Circulation in the kidney.", "content": "Circulation in the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998910"}
{"pmid": "20998911", "title": "Latent period in kala-azar.", "content": "Latent period in kala-azar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998911"}
{"pmid": "20998912", "title": "Perforated peptic ulcer; treated without operation.", "content": "Perforated peptic ulcer; treated without operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998912"}
{"pmid": "20998913", "title": "Sensitivity to penicillin; anaphylaxis and desensitisation.", "content": "Sensitivity to penicillin; anaphylaxis and desensitisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998913"}
{"pmid": "20998914", "title": "Treatment of infantile pellagra; assessment of the value of protein hydrolysates.", "content": "Treatment of infantile pellagra; assessment of the value of protein hydrolysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998914"}
{"pmid": "20998916", "title": "Empirical tests of liver function.", "content": "Empirical tests of liver function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998916"}
{"pmid": "20998915", "title": "Early ovulation.", "content": "Early ovulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998915"}
{"pmid": "20998917", "title": "Perforation of the aorta; by swallowed bones.", "content": "Perforation of the aorta; by swallowed bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998917"}
{"pmid": "20998918", "title": "WORLD problems of nutrition.", "content": "WORLD problems of nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998918"}
{"pmid": "20998919", "title": "Pernicious anemia and carcinoma of the oesophagus.", "content": "Pernicious anemia and carcinoma of the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998919"}
{"pmid": "20998920", "title": "Conducing to the cure; social psychiatry in the treatment of neurosyphilis by induced malaria.", "content": "Conducing to the cure; social psychiatry in the treatment of neurosyphilis by induced malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998920"}
{"pmid": "20998921", "title": "The use of reassurance.", "content": "The use of reassurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998921"}
{"pmid": "20998922", "title": "The post-hepatitis syndrome.", "content": "The post-hepatitis syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998922"}
{"pmid": "20998923", "title": "Pathology of postanal pilonidal sinus; its bearing on treatment.", "content": "Pathology of postanal pilonidal sinus; its bearing on treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998923"}
{"pmid": "20998924", "title": "Nicotinamide methochloride estimations in sprue and amoebiasis.", "content": "Nicotinamide methochloride estimations in sprue and amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998924"}
{"pmid": "20998925", "title": "Relations of steroid hormones and anhydro-hydroxy-progesterone to fibromatosis.", "content": "Relations of steroid hormones and anhydro-hydroxy-progesterone to fibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998925"}
{"pmid": "20998926", "title": "Remedial correction of valgus foot strain by foot pronation exercise.", "content": "Remedial correction of valgus foot strain by foot pronation exercise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998926"}
{"pmid": "20998927", "title": "Pellagragenic activity of indole-3-acetic acid in the rat.", "content": "Pellagragenic activity of indole-3-acetic acid in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998927"}
{"pmid": "20998928", "title": "Children in day nurseries; with special reference to the child under two years old.", "content": "Children in day nurseries; with special reference to the child under two years old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998928"}
{"pmid": "20998929", "title": "The diagnosis and treatment of functional menstrual disorders.", "content": "The diagnosis and treatment of functional menstrual disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998929"}
{"pmid": "20998930", "title": "Diagnosis, a living art.", "content": "Diagnosis, a living art.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998930"}
{"pmid": "20998931", "title": "The alternative method of treatment for fractures of the neck of the femur.", "content": "The alternative method of treatment for fractures of the neck of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998931"}
{"pmid": "20998932", "title": "Use and misuse of aids to hearing.", "content": "Use and misuse of aids to hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998932"}
{"pmid": "20998933", "title": "Double transmesenteric strangulation.", "content": "Double transmesenteric strangulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998933"}
{"pmid": "20998934", "title": "Operation for the removal of the forequarter.", "content": "Operation for the removal of the forequarter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998934"}
{"pmid": "20998935", "title": "The use of plastic materials in surgery.", "content": "The use of plastic materials in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998935"}
{"pmid": "20998936", "title": "The future of medical education.", "content": "The future of medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998936"}
{"pmid": "20998937", "title": "Some thoughts on the pre-clinical period of the medical curriculum.", "content": "Some thoughts on the pre-clinical period of the medical curriculum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998937"}
{"pmid": "20998938", "title": "This examination business.", "content": "This examination business.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998938"}
{"pmid": "20998939", "title": "The Royal College of Surgeons and post-graduate education.", "content": "The Royal College of Surgeons and post-graduate education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998939"}
{"pmid": "20998940", "title": "Visual education.", "content": "Visual education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998940"}
{"pmid": "20998941", "title": "Psychosomatic medicine.", "content": "Psychosomatic medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998941"}
{"pmid": "20998942", "title": "Electrocardiographic changes following tonsillitis.", "content": "Electrocardiographic changes following tonsillitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998942"}
{"pmid": "20998943", "title": "Proteins in obstetrics and gynaecology.", "content": "Proteins in obstetrics and gynaecology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998943"}
{"pmid": "20998944", "title": "Dicumarol therapy.", "content": "Dicumarol therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998944"}
{"pmid": "20998945", "title": "Pharmacology among ancient Hebrews.", "content": "Pharmacology among ancient Hebrews.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998945"}
{"pmid": "20998946", "title": "Psychosomatic problems in gastroenterology.", "content": "Psychosomatic problems in gastroenterology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998946"}
{"pmid": "20998947", "title": "Secondary malignant disease in bone.", "content": "Secondary malignant disease in bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998947"}
{"pmid": "20998948", "title": "Rheumatism.", "content": "Rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998948"}
{"pmid": "20998949", "title": "The treatment of burn injuries in general practice.", "content": "The treatment of burn injuries in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998949"}
{"pmid": "20998950", "title": "Inoculation against bubonic plague.", "content": "Inoculation against bubonic plague.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998950"}
{"pmid": "20998951", "title": "Mal-descent of the testicle.", "content": "Mal-descent of the testicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998951"}
{"pmid": "20998952", "title": "Amenorrhoea.", "content": "Amenorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998952"}
{"pmid": "20998953", "title": "Medical study in 1880.", "content": "Medical study in 1880.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998953"}
{"pmid": "20998954", "title": "Lesions of the facial nerve.", "content": "Lesions of the facial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998954"}
{"pmid": "20998955", "title": "Marriage difficulties and the practitioner.", "content": "Marriage difficulties and the practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998955"}
{"pmid": "20998956", "title": "Recent advances in psychiatry.", "content": "Recent advances in psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998956"}
{"pmid": "20998957", "title": "Fractures of the ribs and sternum.", "content": "Fractures of the ribs and sternum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998957"}
{"pmid": "20998958", "title": "Acute myocardial infarction.", "content": "Acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998958"}
{"pmid": "20998959", "title": "Use of sulfadiazine in presence of hematuria.", "content": "Use of sulfadiazine in presence of hematuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998959"}
{"pmid": "20998960", "title": "The use of ether in the narcoanalysis of patients with war neuroses.", "content": "The use of ether in the narcoanalysis of patients with war neuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998960"}
{"pmid": "20998961", "title": "Enhancing the riboflavin content of mare's milk.", "content": "Enhancing the riboflavin content of mare's milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998961"}
{"pmid": "20998962", "title": "Gold therapy in rheumatoid arthritis.", "content": "Gold therapy in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998962"}
{"pmid": "20998963", "title": "Adenoma of bronchus.", "content": "Adenoma of bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998963"}
{"pmid": "20998964", "title": "Double intussusception and volvulus of ileum, led by adenomatous polyp.", "content": "Double intussusception and volvulus of ileum, led by adenomatous polyp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998964"}
{"pmid": "20998966", "title": "Chiari's syndrome.", "content": "Chiari's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998966"}
{"pmid": "20998965", "title": "A therapeutic score card for rheumatoid arthritis; a standardized method of appraising results of treatment.", "content": "A therapeutic score card for rheumatoid arthritis; a standardized method of appraising results of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998965"}
{"pmid": "20998967", "title": "Recurrent spontaneous emphysema of the mediastinum with concomitant pneumothorax.", "content": "Recurrent spontaneous emphysema of the mediastinum with concomitant pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998967"}
{"pmid": "20998968", "title": "Unilateral tremor of the lower extremity; its association with internal derangement of the ipsilateral knee.", "content": "Unilateral tremor of the lower extremity; its association with internal derangement of the ipsilateral knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998968"}
{"pmid": "20998969", "title": "Present concepts of benign breast disease.", "content": "Present concepts of benign breast disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998969"}
{"pmid": "20998970", "title": "Carcinoma of pancreas, with metastases to regional lymph nodes, liver, lungs and pleura.", "content": "Carcinoma of pancreas, with metastases to regional lymph nodes, liver, lungs and pleura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998970"}
{"pmid": "20998971", "title": "Cirsoid aneurysm of left gastric artery, with secondary peptic erosion.", "content": "Cirsoid aneurysm of left gastric artery, with secondary peptic erosion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998971"}
{"pmid": "20998973", "title": "Nontraumatic spontaneous pneumothorax among military personnel.", "content": "Nontraumatic spontaneous pneumothorax among military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998973"}
{"pmid": "20998972", "title": "Clinical malnutrition in Italy in 1945; nutritional status of selected population groups.", "content": "Clinical malnutrition in Italy in 1945; nutritional status of selected population groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998972"}
{"pmid": "20998974", "title": "Plasma alpha amino nitrogen levels in patients with thermal burns.", "content": "Plasma alpha amino nitrogen levels in patients with thermal burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998974"}
{"pmid": "20998975", "title": "Occupational dermatoses.", "content": "Occupational dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998975"}
{"pmid": "20998976", "title": "Aleukemic leukemia (monocytic or lymphatic), with massive liver involvement?", "content": "Aleukemic leukemia (monocytic or lymphatic), with massive liver involvement?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998976"}
{"pmid": "20998977", "title": "Tuberculous salpingo-oophoritis.", "content": "Tuberculous salpingo-oophoritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998977"}
{"pmid": "20998978", "title": "Socialized medicine; the phantom approaches.", "content": "Socialized medicine; the phantom approaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998978"}
{"pmid": "20998979", "title": "Five years' experience with electric sleep (electric shock) treatment.", "content": "Five years' experience with electric sleep (electric shock) treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998979"}
{"pmid": "20998980", "title": "The use of biopsies in the diagnosis of cancer.", "content": "The use of biopsies in the diagnosis of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998980"}
{"pmid": "20998981", "title": "Carcinoid of the appendix with metastasis.", "content": "Carcinoid of the appendix with metastasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998981"}
{"pmid": "20998982", "title": "Otolaryngology in general practice.", "content": "Otolaryngology in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998982"}
{"pmid": "20998983", "title": "The management of common eye injuries in general practice.", "content": "The management of common eye injuries in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998983"}
{"pmid": "20998984", "title": "Rh factor and erythroblastosis fetalis.", "content": "Rh factor and erythroblastosis fetalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998984"}
{"pmid": "20998985", "title": "Penicillin in acute bacterial endocarditis.", "content": "Penicillin in acute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998985"}
{"pmid": "20998986", "title": "Paroxysmal auricular fibrillation.", "content": "Paroxysmal auricular fibrillation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998986"}
{"pmid": "20999000", "title": "Psychosomatic aspects of arterial hypertension.", "content": "Psychosomatic aspects of arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999000"}
{"pmid": "20999001", "title": "An operation for chronic dacryocystitis (plastic dacryocystorhinostomy).", "content": "An operation for chronic dacryocystitis (plastic dacryocystorhinostomy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999001"}
{"pmid": "20999002", "title": "Evaluation of blood protein and factors in atopic eczema.", "content": "Evaluation of blood protein and factors in atopic eczema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999002"}
{"pmid": "20999003", "title": "Treatment of epidemic diarrhea of the newborn.", "content": "Treatment of epidemic diarrhea of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999003"}
{"pmid": "20999004", "title": "Jewish hygiene and longevity.", "content": "Jewish hygiene and longevity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999004"}
{"pmid": "20999005", "title": "Factors in blood grouping; blood types play vital role in medicine and marriage.", "content": "Factors in blood grouping; blood types play vital role in medicine and marriage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999005"}
{"pmid": "20999006", "title": "Advances in medicine.", "content": "Advances in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999006"}
{"pmid": "20999007", "title": "Advances in surgery.", "content": "Advances in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999007"}
{"pmid": "20999008", "title": "Advances in midwifery.", "content": "Advances in midwifery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999008"}
{"pmid": "20999009", "title": "Advances in paediatrics.", "content": "Advances in paediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999009"}
{"pmid": "20999010", "title": "Advances in endocrinology.", "content": "Advances in endocrinology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999010"}
{"pmid": "20999011", "title": "Advances in dermatology.", "content": "Advances in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999011"}
{"pmid": "20999012", "title": "Advances in the treatment of virus diseases; with particular reference to influenza and the common cold.", "content": "Advances in the treatment of virus diseases; with particular reference to influenza and the common cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999012"}
{"pmid": "20999013", "title": "Advances in urology.", "content": "Advances in urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999013"}
{"pmid": "20998999", "title": "Over diphtherie-psychoses.", "content": "Over diphtherie-psychoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20998999"}
{"pmid": "20999014", "title": "Advances in ophthalmology.", "content": "Advances in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999014"}
{"pmid": "20999015", "title": "Advances in oto-rhino-laryngology.", "content": "Advances in oto-rhino-laryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999015"}
{"pmid": "20999016", "title": "Recent advances in anaesthetics.", "content": "Recent advances in anaesthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999016"}
{"pmid": "20999017", "title": "The early recognition of disease; endocrine disease.", "content": "The early recognition of disease; endocrine disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999017"}
{"pmid": "20999018", "title": "The male sex hormone.", "content": "The male sex hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999018"}
{"pmid": "20999019", "title": "Enlargement of the lymph nodes.", "content": "Enlargement of the lymph nodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999019"}
{"pmid": "20999020", "title": "Migraine.", "content": "Migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999020"}
{"pmid": "20999024", "title": "Shigellosis.", "content": "Shigellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999024"}
{"pmid": "20999029", "title": "Arteritis.", "content": "Arteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999029"}
{"pmid": "20999045", "title": "Spirochaetal jaundice (Weil's disease) does it occur in South Africa?", "content": "Spirochaetal jaundice (Weil's disease) does it occur in South Africa?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999045"}
{"pmid": "20999046", "title": "Some suggestions in the clinical examination of the heart.", "content": "Some suggestions in the clinical examination of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999046"}
{"pmid": "20999047", "title": "Arsenical poisoning of humans resulting from cattle-dipping tanks.", "content": "Arsenical poisoning of humans resulting from cattle-dipping tanks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999047"}
{"pmid": "20999048", "title": "The use of Southey tubes in the treatment of edema.", "content": "The use of Southey tubes in the treatment of edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999048"}
{"pmid": "20999049", "title": "Alloxan diabetes cellular changes, and inhibitory actions of colchicine.", "content": "Alloxan diabetes cellular changes, and inhibitory actions of colchicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999049"}
{"pmid": "20999050", "title": "Orbital tumors.", "content": "Orbital tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999050"}
{"pmid": "20999051", "title": "Testicular tumors and gonadotrophic hormones.", "content": "Testicular tumors and gonadotrophic hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999051"}
{"pmid": "20999052", "title": "The pathological results in cases of bacterial endocarditis treated with penicillin.", "content": "The pathological results in cases of bacterial endocarditis treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999052"}
{"pmid": "20999053", "title": "Some physiological aspects of adolescence.", "content": "Some physiological aspects of adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999053"}
{"pmid": "20999054", "title": "The thymus gland.", "content": "The thymus gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999054"}
{"pmid": "20999055", "title": "Pharmacology of obstetrical analgesia.", "content": "Pharmacology of obstetrical analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999055"}
{"pmid": "20999056", "title": "Gastroscopic findings in chronic duodenal ulcer.", "content": "Gastroscopic findings in chronic duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999056"}
{"pmid": "20999057", "title": "Antirickettsial activity of para-amino-benzoic acid; evaluation and significance of PABA blood levels in guinea pigs with reference to spotted fever treatment.", "content": "Antirickettsial activity of para-amino-benzoic acid; evaluation and significance of PABA blood levels in guinea pigs with reference to spotted fever treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999057"}
{"pmid": "20999058", "title": "Pathogenicity of the aspergilli of otomycosis.", "content": "Pathogenicity of the aspergilli of otomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999058"}
{"pmid": "20999060", "title": "Physiological responses of adolescents to exercise.", "content": "Physiological responses of adolescents to exercise.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999060"}
{"pmid": "20999059", "title": "Coexistence of the antibodies of yellow fever and Weil's disease in human serum.", "content": "Coexistence of the antibodies of yellow fever and Weil's disease in human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999059"}
{"pmid": "20999061", "title": "Neuroectodermal tumors containing neoplastic neuronal elements; ganglioneuroma, spongioneuroblastoma and glioneuroma; with a clinicopathologic report of 11 cases and a discussion of their origin and classification.", "content": "Neuroectodermal tumors containing neoplastic neuronal elements; ganglioneuroma, spongioneuroblastoma and glioneuroma; with a clinicopathologic report of 11 cases and a discussion of their origin and classification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999061"}
{"pmid": "20999062", "title": "Naval and Marine Corps casualties in the wars of the United States.", "content": "Naval and Marine Corps casualties in the wars of the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999062"}
{"pmid": "20999063", "title": "Intractable amebiasis; a warning.", "content": "Intractable amebiasis; a warning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999063"}
{"pmid": "20999064", "title": "A bacteriologic study of the resistance of organisms isolated from cases of non-specific urethritis to three chemotherapeutic agents.", "content": "A bacteriologic study of the resistance of organisms isolated from cases of non-specific urethritis to three chemotherapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999064"}
{"pmid": "20999065", "title": "[Alexander, Rose, transl.] Relation, historical and surgical, of the expedition of the Army of the Orient, in Egypt and in Syria.", "content": "[Alexander, Rose, transl.] Relation, historical and surgical, of the expedition of the Army of the Orient, in Egypt and in Syria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999065"}
{"pmid": "20999066", "title": "Baron Larrey, surgeon to the Emperor.", "content": "Baron Larrey, surgeon to the Emperor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999066"}
{"pmid": "20999067", "title": "TRANSVERSE Myelitis Conference held at Hammond General Hospital, Modesto, California, June 24-25, 1945. Modesto, California, U.S. Army Service Forces Ninth Service Command, 1945.", "content": "TRANSVERSE Myelitis Conference held at Hammond General Hospital, Modesto, California, June 24-25, 1945. Modesto, California, U.S. Army Service Forces Ninth Service Command, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999067"}
{"pmid": "20999068", "title": "Urological complications of cases of transverse myelitis.", "content": "Urological complications of cases of transverse myelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999068"}
{"pmid": "20999069", "title": "Treatment of the bladder.", "content": "Treatment of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999069"}
{"pmid": "20999070", "title": "Treatment of decubitus ulcers.", "content": "Treatment of decubitus ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999070"}
{"pmid": "20999071", "title": "Methods of regulating bowel function.", "content": "Methods of regulating bowel function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999071"}
{"pmid": "20999072", "title": "Methods of improving function of the lower extremities by mechanical aids.", "content": "Methods of improving function of the lower extremities by mechanical aids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999072"}
{"pmid": "20999073", "title": "Problems involved in the mental and physical readjustment to restricted life.", "content": "Problems involved in the mental and physical readjustment to restricted life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999073"}
{"pmid": "20999074", "title": "Neurosurgical problems.", "content": "Neurosurgical problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999074"}
{"pmid": "20999075", "title": "Nutrition.", "content": "Nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999075"}
{"pmid": "20999076", "title": "Administrative and medical program for the best care of transverse myelitis cases.", "content": "Administrative and medical program for the best care of transverse myelitis cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999076"}
{"pmid": "20999077", "title": "A cytological study of yeast (Saccharomyces cerevisiae).", "content": "A cytological study of yeast (Saccharomyces cerevisiae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999077"}
{"pmid": "20999078", "title": "Significance of human individuality in world affairs.", "content": "Significance of human individuality in world affairs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999078"}
{"pmid": "20999079", "title": "The concept of vestigial organs and the vascular cryptogams.", "content": "The concept of vestigial organs and the vascular cryptogams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999079"}
{"pmid": "20999080", "title": "An instance of the occurrence of Monilia albicans (Candida albicans) in dental caries.", "content": "An instance of the occurrence of Monilia albicans (Candida albicans) in dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999080"}
{"pmid": "20999081", "title": "Chemistry of kurchi seeds; isolation of galactose from the picric acid hydrolysis of the glyco-alkaloid.", "content": "Chemistry of kurchi seeds; isolation of galactose from the picric acid hydrolysis of the glyco-alkaloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999081"}
{"pmid": "20999082", "title": "Refractive index of milk.", "content": "Refractive index of milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999082"}
{"pmid": "20999083", "title": "The cytology of yeast.", "content": "The cytology of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999083"}
{"pmid": "20999084", "title": "Chromosome numbers in Bambuseae.", "content": "Chromosome numbers in Bambuseae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999084"}
{"pmid": "20999085", "title": "Another probable origin of the word chemistry from the Chinese.", "content": "Another probable origin of the word chemistry from the Chinese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999085"}
{"pmid": "20999086", "title": "Constitution of oroxylin-A.", "content": "Constitution of oroxylin-A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999086"}
{"pmid": "20999087", "title": "Preliminary description and analysis of the first spectrum of uranium.", "content": "Preliminary description and analysis of the first spectrum of uranium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999087"}
{"pmid": "20999088", "title": "An arrangement with small solid angle for measurement of beta rays.", "content": "An arrangement with small solid angle for measurement of beta rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999088"}
{"pmid": "20999089", "title": "Purification, purity, and freezing points of 31 hydrocarbons of the API-NBS series.", "content": "Purification, purity, and freezing points of 31 hydrocarbons of the API-NBS series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999089"}
{"pmid": "20999090", "title": "Absorption measurements for broad beams of 1- and 2-million-volt X-rays.", "content": "Absorption measurements for broad beams of 1- and 2-million-volt X-rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999090"}
{"pmid": "20999091", "title": "Effect of reaction between mercury and oxygen upon polarographic waves of certain metals at small concentrations.", "content": "Effect of reaction between mercury and oxygen upon polarographic waves of certain metals at small concentrations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999091"}
{"pmid": "20999092", "title": "Electrode function (pH response) of potash-silica glasses.", "content": "Electrode function (pH response) of potash-silica glasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999092"}
{"pmid": "20999094", "title": "New developments in relativistic quantum theory.", "content": "New developments in relativistic quantum theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999094"}
{"pmid": "20999095", "title": "HETEROGENESIS and the origin of viruses.", "content": "HETEROGENESIS and the origin of viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999095"}
{"pmid": "20999093", "title": "FUTURE organisation of scientific research.", "content": "FUTURE organisation of scientific research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999093"}
{"pmid": "20999096", "title": "MORBID anatomy in the University of London. [Dorothy Russell].", "content": "MORBID anatomy in the University of London. [Dorothy Russell].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999096"}
{"pmid": "20999097", "title": "Viscosity of associated liquids.", "content": "Viscosity of associated liquids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999097"}
{"pmid": "20999098", "title": "Production of metabolic benzpyrene derivatives in vitro.", "content": "Production of metabolic benzpyrene derivatives in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999098"}
{"pmid": "20999099", "title": "Transmission of L. carinii to laboratory animals.", "content": "Transmission of L. carinii to laboratory animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999099"}
{"pmid": "20999101", "title": "Moulds producing penicillin-like antibiotics.", "content": "Moulds producing penicillin-like antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999101"}
{"pmid": "20999100", "title": "Biochemical research on chemical warfare agents.", "content": "Biochemical research on chemical warfare agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999100"}
{"pmid": "20999102", "title": "Use of normal human plasma fractions in haemophilia.", "content": "Use of normal human plasma fractions in haemophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999102"}
{"pmid": "20999103", "title": "Kinetics of aromatic nitration; the nitronium ion.", "content": "Kinetics of aromatic nitration; the nitronium ion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999103"}
{"pmid": "20999104", "title": "Thermal migration of macromolecules.", "content": "Thermal migration of macromolecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999104"}
{"pmid": "20999105", "title": "Spectroscopic arguments for isomeric structures in alpha-chloro-acids.", "content": "Spectroscopic arguments for isomeric structures in alpha-chloro-acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999105"}
{"pmid": "20999106", "title": "BIOLOGICAL Institute of Tihany, Hungary.", "content": "BIOLOGICAL Institute of Tihany, Hungary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999106"}
{"pmid": "20999107", "title": "Tropic proofing of optical instruments by a fungicide.", "content": "Tropic proofing of optical instruments by a fungicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999107"}
{"pmid": "20999108", "title": "Fibrous proteins.", "content": "Fibrous proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999108"}
{"pmid": "20999109", "title": "Cryoscopic proof of the formation of nitronium ion.", "content": "Cryoscopic proof of the formation of nitronium ion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999109"}
{"pmid": "20999110", "title": "Short-lived radioactivity from lithium bombarded with neutrons.", "content": "Short-lived radioactivity from lithium bombarded with neutrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999110"}
{"pmid": "20999111", "title": "Symbiotic aspects of nitrification.", "content": "Symbiotic aspects of nitrification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999111"}
{"pmid": "20999112", "title": "Formation of hydrogen peroxide by spermatozoa and its inhibitory effect of respiration.", "content": "Formation of hydrogen peroxide by spermatozoa and its inhibitory effect of respiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999112"}
{"pmid": "20999113", "title": "Enamel formation in the rat's incisor tooth.", "content": "Enamel formation in the rat's incisor tooth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999113"}
{"pmid": "20999114", "title": "The incomplete antibody; a quantitative aspect.", "content": "The incomplete antibody; a quantitative aspect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999114"}
{"pmid": "20999115", "title": "Jubilee of the Marine Biological Station, Millport.", "content": "Jubilee of the Marine Biological Station, Millport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999115"}
{"pmid": "20999116", "title": "Composition of the antimalarial drug R.63 and the Ing and Manske hydrazine hydrolysis of N-substituted phthalimides.", "content": "Composition of the antimalarial drug R.63 and the Ing and Manske hydrazine hydrolysis of N-substituted phthalimides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999116"}
{"pmid": "20999117", "title": "Organic nitrogen compounds as nitrogen nutrition for higher plants.", "content": "Organic nitrogen compounds as nitrogen nutrition for higher plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999117"}
{"pmid": "20999118", "title": "Molybdenumthiocyanate complex.", "content": "Molybdenumthiocyanate complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999118"}
{"pmid": "20999119", "title": "Useful X-ray mutations in plants.", "content": "Useful X-ray mutations in plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999119"}
{"pmid": "20999120", "title": "Cytological basis of high fertility in autotetraploid buckwheat.", "content": "Cytological basis of high fertility in autotetraploid buckwheat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999120"}
{"pmid": "20999121", "title": "Development of milk recording in Great Britain.", "content": "Development of milk recording in Great Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999121"}
{"pmid": "20999122", "title": "Sub-shock insulin therapy in anxiety states and anxiety depressions.", "content": "Sub-shock insulin therapy in anxiety states and anxiety depressions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999122"}
{"pmid": "20999123", "title": "Prediction of the immediate outcome of shock therapy in dementia praecox.", "content": "Prediction of the immediate outcome of shock therapy in dementia praecox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999123"}
{"pmid": "20999124", "title": "The role of psychiatry in industry.", "content": "The role of psychiatry in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999124"}
{"pmid": "20999125", "title": "The 96th General Hospital; the story of an Army neuropsychiatric hospital.", "content": "The 96th General Hospital; the story of an Army neuropsychiatric hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999125"}
{"pmid": "20999126", "title": "Amyotrophic lateral sclerosis.", "content": "Amyotrophic lateral sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999126"}
{"pmid": "20999127", "title": "The occurrence and function of nerves in the growing antlers of deer.", "content": "The occurrence and function of nerves in the growing antlers of deer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999127"}
{"pmid": "20999128", "title": "Components and distribution of the nerves of the parotid and submandibular glands.", "content": "Components and distribution of the nerves of the parotid and submandibular glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999128"}
{"pmid": "20999129", "title": "Components and distribution of the spermatic nerves and the nerves of the vas deferens.", "content": "Components and distribution of the spermatic nerves and the nerves of the vas deferens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999129"}
{"pmid": "20999130", "title": "The pyramidal tract; speed of degeneration in axons following ablation of cells of origin in the monkey.", "content": "The pyramidal tract; speed of degeneration in axons following ablation of cells of origin in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999130"}
{"pmid": "20999131", "title": "Observations on the central nervous system of Leptoplana acticola.", "content": "Observations on the central nervous system of Leptoplana acticola.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999131"}
{"pmid": "20999132", "title": "The mammalian midbrain and isthmus regions; the fiber connections; the relations of the tegmentum of the midbrain with the basal ganglia in Macaca mulatta.", "content": "The mammalian midbrain and isthmus regions; the fiber connections; the relations of the tegmentum of the midbrain with the basal ganglia in Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999132"}
{"pmid": "20999133", "title": "Metrical and non-metrical features of the muscular branches of the radial nerve.", "content": "Metrical and non-metrical features of the muscular branches of the radial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999133"}
{"pmid": "20999134", "title": "Metrical and non-metrical features of the muscular branches of the ulnar nerve.", "content": "Metrical and non-metrical features of the muscular branches of the ulnar nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999134"}
{"pmid": "20999135", "title": "The distributions of axons from the motor cell groups in the spinal cord of the fetal sheep.", "content": "The distributions of axons from the motor cell groups in the spinal cord of the fetal sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999135"}
{"pmid": "20999136", "title": "The ratio of nerve fibers to nerve cells in the geniculate ganglion.", "content": "The ratio of nerve fibers to nerve cells in the geniculate ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999136"}
{"pmid": "20999137", "title": "The influence of emotion on the human electro-encephalogran.", "content": "The influence of emotion on the human electro-encephalogran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999137"}
{"pmid": "20999138", "title": "Combat exhaustion.", "content": "Combat exhaustion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999138"}
{"pmid": "20999139", "title": "The closed head injury syndrome due to blast.", "content": "The closed head injury syndrome due to blast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999139"}
{"pmid": "20999140", "title": "Criteria for the stages of pentothal anesthesia.", "content": "Criteria for the stages of pentothal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999140"}
{"pmid": "20999141", "title": "An evaluation of the therapeutic role of narco-analysis in mental disorders.", "content": "An evaluation of the therapeutic role of narco-analysis in mental disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999141"}
{"pmid": "20999142", "title": "Schistosomiasis of the central nervous system.", "content": "Schistosomiasis of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999142"}
{"pmid": "20999143", "title": "Porphyria; neuropsychiatric aspects in the case of a Negro.", "content": "Porphyria; neuropsychiatric aspects in the case of a Negro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999143"}
{"pmid": "20999144", "title": "Clinical implications of the Bellevue-Wechsler test (with particular reference to brain damage cases).", "content": "Clinical implications of the Bellevue-Wechsler test (with particular reference to brain damage cases).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999144"}
{"pmid": "20999145", "title": "Fatigue and the adrenal cortex.", "content": "Fatigue and the adrenal cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999145"}
{"pmid": "20999153", "title": "The dental health education approach in Tennessee.", "content": "The dental health education approach in Tennessee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999153"}
{"pmid": "20999147", "title": "Hormonal modification of social behavior; the effects of sex-hormone administration on the social dominance status of the female-castrate chimpanzee.", "content": "Hormonal modification of social behavior; the effects of sex-hormone administration on the social dominance status of the female-castrate chimpanzee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999147"}
{"pmid": "20999146", "title": "Studies on the nature of certain symptoms associated with cardiovascular disorders.", "content": "Studies on the nature of certain symptoms associated with cardiovascular disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999146"}
{"pmid": "20999156", "title": "Malaria.", "content": "Malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999156"}
{"pmid": "20999155", "title": "Silicosis.", "content": "Silicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999155"}
{"pmid": "20999154", "title": "Korea; a challenge to western nursing.", "content": "Korea; a challenge to western nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999154"}
{"pmid": "20999157", "title": "Nursing care in malaria.", "content": "Nursing care in malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999157"}
{"pmid": "20999158", "title": "Depression, then suicide.", "content": "Depression, then suicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999158"}
{"pmid": "20999148", "title": "An electrocardiographic study of psychoneurotic patients.", "content": "An electrocardiographic study of psychoneurotic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999148"}
{"pmid": "20999159", "title": "The high-fluid régime for edema.", "content": "The high-fluid régime for edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999159"}
{"pmid": "20999160", "title": "The nurse's rôle in the high-fluid régime for edema.", "content": "The nurse's rôle in the high-fluid régime for edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999160"}
{"pmid": "20999161", "title": "Hypospadias; nursing care in surgical repair.", "content": "Hypospadias; nursing care in surgical repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999161"}
{"pmid": "20999162", "title": "Poliomyelitis problems; the Alabama epidemic.", "content": "Poliomyelitis problems; the Alabama epidemic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999162"}
{"pmid": "20999149", "title": "Inguinal hernia in psychiatric patients.", "content": "Inguinal hernia in psychiatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999149"}
{"pmid": "20999163", "title": "Audiovisual materials for nursing education.", "content": "Audiovisual materials for nursing education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999163"}
{"pmid": "20999164", "title": "The paraplegia patient; a nursing care study.", "content": "The paraplegia patient; a nursing care study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999164"}
{"pmid": "20999166", "title": "Orthopaedic nursing.", "content": "Orthopaedic nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999166"}
{"pmid": "20999167", "title": "Tuberculosis and nurses.", "content": "Tuberculosis and nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999167"}
{"pmid": "20999168", "title": "Some recent shifts in humanitarian feelings.", "content": "Some recent shifts in humanitarian feelings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999168"}
{"pmid": "20999169", "title": "Nursing service in relation to community needs.", "content": "Nursing service in relation to community needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999169"}
{"pmid": "20999170", "title": "Nursing education in a state of flux.", "content": "Nursing education in a state of flux.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999170"}
{"pmid": "20999171", "title": "Development of medicine and nursing service; in a silver-lead ore-producing mine.", "content": "Development of medicine and nursing service; in a silver-lead ore-producing mine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999171"}
{"pmid": "20999172", "title": "The evaluation of the graduate professional nurse, in industry.", "content": "The evaluation of the graduate professional nurse, in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999172"}
{"pmid": "20999173", "title": "What have Canadian nurses to offer industry?", "content": "What have Canadian nurses to offer industry?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999173"}
{"pmid": "20999165", "title": "Observations on the control of hospital infection.", "content": "Observations on the control of hospital infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999165"}
{"pmid": "20999174", "title": "Industrial nursing, and industrial morale.", "content": "Industrial nursing, and industrial morale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999174"}
{"pmid": "20999175", "title": "Some elementary precautions in nursing tuberculosis patients.", "content": "Some elementary precautions in nursing tuberculosis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999175"}
{"pmid": "20999177", "title": "Pyogenic granuloma.", "content": "Pyogenic granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999177"}
{"pmid": "20999176", "title": "Domiciliary midwifery in Calcutta.", "content": "Domiciliary midwifery in Calcutta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999176"}
{"pmid": "20999178", "title": "Step by step application of a pressure bandage to the knee.", "content": "Step by step application of a pressure bandage to the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999178"}
{"pmid": "20999179", "title": "Midwifery training in Vienna.", "content": "Midwifery training in Vienna.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999179"}
{"pmid": "20999180", "title": "Relaxation and easy childbirth; how the midwife can help.", "content": "Relaxation and easy childbirth; how the midwife can help.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999180"}
{"pmid": "20999181", "title": "Control of infectious diseases; notification.", "content": "Control of infectious diseases; notification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999181"}
{"pmid": "20999182", "title": "Treatment of arterial injuries.", "content": "Treatment of arterial injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999182"}
{"pmid": "20999183", "title": "Laxatives and diuretics; prescriptions for constipation and diarrhoea.", "content": "Laxatives and diuretics; prescriptions for constipation and diarrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999183"}
{"pmid": "20999184", "title": "Carcinoma of the stomach; treated with transthoracic total gastrectomy.", "content": "Carcinoma of the stomach; treated with transthoracic total gastrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999184"}
{"pmid": "20999185", "title": "Relaxation and easy childbirth; the midwife's part in the labour stages.", "content": "Relaxation and easy childbirth; the midwife's part in the labour stages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999185"}
{"pmid": "20999187", "title": "Treatment of obstructed labour.", "content": "Treatment of obstructed labour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999187"}
{"pmid": "20999186", "title": "Hypertension and its treatment.", "content": "Hypertension and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999186"}
{"pmid": "20999188", "title": "Typhoid fever and its treatment.", "content": "Typhoid fever and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999188"}
{"pmid": "20999189", "title": "Mental aspect of hospital rehabilitation.", "content": "Mental aspect of hospital rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999189"}
{"pmid": "20999190", "title": "Rheumatism in industry.", "content": "Rheumatism in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999190"}
{"pmid": "20999191", "title": "General nursing by the district nurse.", "content": "General nursing by the district nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999191"}
{"pmid": "20999192", "title": "Extra-uterine pregnancy.", "content": "Extra-uterine pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999192"}
{"pmid": "20999193", "title": "Some instruments and accessories used in genito-urinary surgery.", "content": "Some instruments and accessories used in genito-urinary surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999193"}
{"pmid": "20999194", "title": "Experiment in teaching for health visitors.", "content": "Experiment in teaching for health visitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999194"}
{"pmid": "20999195", "title": "Mental health of the nurse.", "content": "Mental health of the nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999195"}
{"pmid": "20999196", "title": "[Monocular vision] treatment needed to fit him for industry.", "content": "[Monocular vision] treatment needed to fit him for industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999196"}
{"pmid": "20999197", "title": "A round of Copenhagen hospitals.", "content": "A round of Copenhagen hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999197"}
{"pmid": "20999199", "title": "Care and sterilisation of direct vision resectoscopes and cystoscopes.", "content": "Care and sterilisation of direct vision resectoscopes and cystoscopes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999199"}
{"pmid": "20999198", "title": "Correlation of physical and emotional phenomena of natural labour.", "content": "Correlation of physical and emotional phenomena of natural labour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999198"}
{"pmid": "20999200", "title": "Industrial nurse's equipment.", "content": "Industrial nurse's equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999200"}
{"pmid": "20999201", "title": "Paralysis agitans.", "content": "Paralysis agitans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999201"}
{"pmid": "20999202", "title": "Three phases of natural labour.", "content": "Three phases of natural labour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999202"}
{"pmid": "20999203", "title": "Treatment of minor industrial injuries; three main types of injury.", "content": "Treatment of minor industrial injuries; three main types of injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999203"}
{"pmid": "20999204", "title": "Role of the midwife in preventive medicine.", "content": "Role of the midwife in preventive medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999204"}
{"pmid": "20999206", "title": "Functional paralysis treated by hypnosis.", "content": "Functional paralysis treated by hypnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999206"}
{"pmid": "20999205", "title": "Smallest baby known to live.", "content": "Smallest baby known to live.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999205"}
{"pmid": "20999207", "title": "The progress of nursing.", "content": "The progress of nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999207"}
{"pmid": "20999208", "title": "Stockholm, the city of many islands.", "content": "Stockholm, the city of many islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999208"}
{"pmid": "20999209", "title": "Social medicine; social aspects of physical defects and tuberculosis.", "content": "Social medicine; social aspects of physical defects and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999209"}
{"pmid": "20999210", "title": "AFRICAN midwife, good progress in Nairobi.", "content": "AFRICAN midwife, good progress in Nairobi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999210"}
{"pmid": "20999211", "title": "The psychological aspects in tuberculosis.", "content": "The psychological aspects in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999211"}
{"pmid": "20999215", "title": "Fracture of shaft of the femur treated with Küntscher intramedullary nail.", "content": "Fracture of shaft of the femur treated with Küntscher intramedullary nail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999215"}
{"pmid": "20999216", "title": "The nursing staff and present day anaesthetic procedure.", "content": "The nursing staff and present day anaesthetic procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999216"}
{"pmid": "20999217", "title": "Development and aims of antenatal care.", "content": "Development and aims of antenatal care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999217"}
{"pmid": "20999218", "title": "A child welfare team in Berlin.", "content": "A child welfare team in Berlin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999218"}
{"pmid": "20999213", "title": "Social medicine; industry.", "content": "Social medicine; industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999213"}
{"pmid": "20999212", "title": "Penicillin in infectious diseases.", "content": "Penicillin in infectious diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999212"}
{"pmid": "20999226", "title": "Public Health Nursing's first week.", "content": "Public Health Nursing's first week.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999226"}
{"pmid": "20999227", "title": "School health institutes in California.", "content": "School health institutes in California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999227"}
{"pmid": "20999214", "title": "The new social insurance scheme.", "content": "The new social insurance scheme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999214"}
{"pmid": "20999229", "title": "Public health nursing in Changchow.", "content": "Public health nursing in Changchow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999229"}
{"pmid": "20999228", "title": "The Health Institute of the UAW-CIO.", "content": "The Health Institute of the UAW-CIO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999228"}
{"pmid": "20999219", "title": "Penicillin; its history and uses.", "content": "Penicillin; its history and uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999219"}
{"pmid": "20999230", "title": "A day with a rural public health nurse.", "content": "A day with a rural public health nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999230"}
{"pmid": "20999231", "title": "Sociological implications of a rat control program.", "content": "Sociological implications of a rat control program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999231"}
{"pmid": "20999232", "title": "RADIOLOGY, the application of x-rays to medicine, industry and physics.", "content": "RADIOLOGY, the application of x-rays to medicine, industry and physics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999232"}
{"pmid": "20999233", "title": "The modern treatment of pneumonia in infants.", "content": "The modern treatment of pneumonia in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999233"}
{"pmid": "20999234", "title": "APPETITE problem in infancy and childhood.", "content": "APPETITE problem in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999234"}
{"pmid": "20999220", "title": "Some common skin diseases in children.", "content": "Some common skin diseases in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999220"}
{"pmid": "20999235", "title": "Selection of color vision tests for the Army Air Forces; a summary of studies made at the Army Air Forces School of Aviation Medicine.", "content": "Selection of color vision tests for the Army Air Forces; a summary of studies made at the Army Air Forces School of Aviation Medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999235"}
{"pmid": "20999236", "title": "Opthalmic penicillin ointments.", "content": "Opthalmic penicillin ointments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999236"}
{"pmid": "20999237", "title": "Effects of atropine sulfate, methylatropine nitrate (metropine) and homatropine hydrobromide on adult human eyes.", "content": "Effects of atropine sulfate, methylatropine nitrate (metropine) and homatropine hydrobromide on adult human eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999237"}
{"pmid": "20999222", "title": "Science in wartime.", "content": "Science in wartime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999222"}
{"pmid": "20999221", "title": "Lupus vulgaris.", "content": "Lupus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999221"}
{"pmid": "20999238", "title": "Night vision; a comparison and critique of various procedures used for night vision testing.", "content": "Night vision; a comparison and critique of various procedures used for night vision testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999238"}
{"pmid": "20999223", "title": "Sanatorium regime.", "content": "Sanatorium regime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999223"}
{"pmid": "20999224", "title": "Ligation of ductus arteriosus.", "content": "Ligation of ductus arteriosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999224"}
{"pmid": "20999239", "title": "Reduction of reflections.", "content": "Reduction of reflections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999239"}
{"pmid": "20999240", "title": "Preservation of corneal tissue for transplantation.", "content": "Preservation of corneal tissue for transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999240"}
{"pmid": "20999225", "title": "The modern approach to ophthalmology.", "content": "The modern approach to ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999225"}
{"pmid": "20999241", "title": "Metabolism of the retina.", "content": "Metabolism of the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999241"}
{"pmid": "20999242", "title": "Retrolental fibroplasia in premature infants; Terry's syndrome.", "content": "Retrolental fibroplasia in premature infants; Terry's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999242"}
{"pmid": "20999243", "title": "Construction of lacrimal passage; report of a case and discussion of experience with the procedure.", "content": "Construction of lacrimal passage; report of a case and discussion of experience with the procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999243"}
{"pmid": "20999244", "title": "Retrolental fibroplasia.", "content": "Retrolental fibroplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999244"}
{"pmid": "20999245", "title": "The incidence of trachoma in the southern highlands province of Tanganyika.", "content": "The incidence of trachoma in the southern highlands province of Tanganyika.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999245"}
{"pmid": "20999246", "title": "Corneal vascularisation in chronic disease.", "content": "Corneal vascularisation in chronic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999246"}
{"pmid": "20999247", "title": "Iridencleisis; a modification.", "content": "Iridencleisis; a modification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999247"}
{"pmid": "20999248", "title": "Sulphonamides and penicillin in the treatment of trachoma.", "content": "Sulphonamides and penicillin in the treatment of trachoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999248"}
{"pmid": "20999249", "title": "Bilateral detachment of the choroid of unusual duration following corneo-scleral trephine.", "content": "Bilateral detachment of the choroid of unusual duration following corneo-scleral trephine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999249"}
{"pmid": "20999250", "title": "Ophthalmic experiences in the Royal Air Force.", "content": "Ophthalmic experiences in the Royal Air Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999250"}
{"pmid": "20999251", "title": "Sattler's veil.", "content": "Sattler's veil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999251"}
{"pmid": "20999252", "title": "Conjunctival findings in cases of cold haemagglutination.", "content": "Conjunctival findings in cases of cold haemagglutination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999252"}
{"pmid": "20999253", "title": "Egypt's contribution during the war to protection against disease through care of eyes of babies.", "content": "Egypt's contribution during the war to protection against disease through care of eyes of babies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999253"}
{"pmid": "20999254", "title": "Proptosis; differential diagnosis.", "content": "Proptosis; differential diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999254"}
{"pmid": "20999255", "title": "Discussion on blindness in prisoners of war.", "content": "Discussion on blindness in prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999255"}
{"pmid": "20999281", "title": "Neurinoma of the facial nerve.", "content": "Neurinoma of the facial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999281"}
{"pmid": "20999282", "title": "Stenosis of the nasopharynx and its correction.", "content": "Stenosis of the nasopharynx and its correction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999282"}
{"pmid": "20999283", "title": "Concussion deafness.", "content": "Concussion deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999283"}
{"pmid": "20999284", "title": "Tuberculosis of the tonsils.", "content": "Tuberculosis of the tonsils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999284"}
{"pmid": "20999285", "title": "Penicillin administered locally in treatment of disease of nasal accessory sinus; evaluation of bacterial sensitivity.", "content": "Penicillin administered locally in treatment of disease of nasal accessory sinus; evaluation of bacterial sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999285"}
{"pmid": "20999286", "title": "Auditory acuity of artillerymen and of rifle coaches.", "content": "Auditory acuity of artillerymen and of rifle coaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999286"}
{"pmid": "20999287", "title": "Gradenigo's syndrome.", "content": "Gradenigo's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999287"}
{"pmid": "20999288", "title": "Diseases and defects in aircrew trainees; ear, nose, throat and oral cavity.", "content": "Diseases and defects in aircrew trainees; ear, nose, throat and oral cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999288"}
{"pmid": "20999289", "title": "Obstruction of the nasopharynx secondary to choanal polyp of antral origin.", "content": "Obstruction of the nasopharynx secondary to choanal polyp of antral origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999289"}
{"pmid": "20999290", "title": "Fatigue test and its significance.", "content": "Fatigue test and its significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999290"}
{"pmid": "20999291", "title": "Peroral endoscopy.", "content": "Peroral endoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999291"}
{"pmid": "20999292", "title": "Penicillin in otorhinolaryngology.", "content": "Penicillin in otorhinolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999292"}
{"pmid": "20999293", "title": "Congenital sinuses of the external ear.", "content": "Congenital sinuses of the external ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999293"}
{"pmid": "20999295", "title": "Perforation of the aorta by a foreign body in the oesophagus.", "content": "Perforation of the aorta by a foreign body in the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999295"}
{"pmid": "20999294", "title": "Fenestration of the labyrinth; the transtympanic route.", "content": "Fenestration of the labyrinth; the transtympanic route.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999294"}
{"pmid": "20999296", "title": "Presidential address [deafness].", "content": "Presidential address [deafness].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999296"}
{"pmid": "20999298", "title": "Volume control adjustment in hearing aid selection.", "content": "Volume control adjustment in hearing aid selection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999298"}
{"pmid": "20999297", "title": "Stiffness lesions of the conducting mechanism.", "content": "Stiffness lesions of the conducting mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999297"}
{"pmid": "20999299", "title": "Reinnervation of a paralyzed vocal cord.", "content": "Reinnervation of a paralyzed vocal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999299"}
{"pmid": "20999300", "title": "Diagnosis and evaluation of fenestration.", "content": "Diagnosis and evaluation of fenestration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999300"}
{"pmid": "20999301", "title": "The use of glycerite of hydrogen peroxide in inflammatory aural conditions.", "content": "The use of glycerite of hydrogen peroxide in inflammatory aural conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999301"}
{"pmid": "20999307", "title": "The fulminant form of epidemic hepatitis.", "content": "The fulminant form of epidemic hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999307"}
{"pmid": "20999308", "title": "Bone infarcts.", "content": "Bone infarcts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999308"}
{"pmid": "20999309", "title": "The pathology of Japanese B encephalitis.", "content": "The pathology of Japanese B encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999309"}
{"pmid": "20999310", "title": "Human salmonellosis due to Salmonella senftenberg.", "content": "Human salmonellosis due to Salmonella senftenberg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999310"}
{"pmid": "20999311", "title": "Arterial calcification in infancy with special reference to the coronary arteries.", "content": "Arterial calcification in infancy with special reference to the coronary arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999311"}
{"pmid": "20999312", "title": "Skeletal changes caused by the combined administration of thyroxin and estrogen.", "content": "Skeletal changes caused by the combined administration of thyroxin and estrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999312"}
{"pmid": "20999314", "title": "The occurrence of neoplasms in the liver, lungs, and other tissues of rats as a result of prolonged choline deficiency.", "content": "The occurrence of neoplasms in the liver, lungs, and other tissues of rats as a result of prolonged choline deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999314"}
{"pmid": "20999313", "title": "Leiomyoma of the ventral ligament of the oviduct of the chicken.", "content": "Leiomyoma of the ventral ligament of the oviduct of the chicken.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999313"}
{"pmid": "20999315", "title": "Some observations on a disease of zebu cattle associated with infestation by the hookworm, Bunostomum phlebotomum.", "content": "Some observations on a disease of zebu cattle associated with infestation by the hookworm, Bunostomum phlebotomum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999315"}
{"pmid": "20999316", "title": "Immunisation against fowl plague with crystal-violet vaccine.", "content": "Immunisation against fowl plague with crystal-violet vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999316"}
{"pmid": "20999318", "title": "Trials with phenothiazine-salt mixtures for the prevention of parasitic gastritis in lambs.", "content": "Trials with phenothiazine-salt mixtures for the prevention of parasitic gastritis in lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999318"}
{"pmid": "20999317", "title": "The estimation of penicillin in blood serum and milk of bovines after intramuscular injection.", "content": "The estimation of penicillin in blood serum and milk of bovines after intramuscular injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999317"}
{"pmid": "20999319", "title": "Studies on Corynebacterium renale; a systematic study of a number of strains.", "content": "Studies on Corynebacterium renale; a systematic study of a number of strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999319"}
{"pmid": "20999320", "title": "Studies on Corynebacterium renale; the experimental pathogenicity for mice.", "content": "Studies on Corynebacterium renale; the experimental pathogenicity for mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999320"}
{"pmid": "20999321", "title": "Blood amino nitrogen levels; changes in blood amino nitrogen levels following ingestion of proteins and of a protein hydrolysate in infants with normal and with deficient pancreatic function.", "content": "Blood amino nitrogen levels; changes in blood amino nitrogen levels following ingestion of proteins and of a protein hydrolysate in infants with normal and with deficient pancreatic function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999321"}
{"pmid": "20999323", "title": "Treatment of impetigo neonatorum with minimal doses of penicillin.", "content": "Treatment of impetigo neonatorum with minimal doses of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999323"}
{"pmid": "20999322", "title": "Criteria for recognition of neuroses in children.", "content": "Criteria for recognition of neuroses in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999322"}
{"pmid": "20999324", "title": "Clinical applications of chick embryo cultures; primary diagnosis of meningitis and study of spinal fluid in meningococcemia with meningitis; in vivo streptomycin sensitivity test.", "content": "Clinical applications of chick embryo cultures; primary diagnosis of meningitis and study of spinal fluid in meningococcemia with meningitis; in vivo streptomycin sensitivity test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999324"}
{"pmid": "20999325", "title": "Adenomas of the large intestine in children.", "content": "Adenomas of the large intestine in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999325"}
{"pmid": "20999326", "title": "Bronchiectasis following primary tuberculosis.", "content": "Bronchiectasis following primary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999326"}
{"pmid": "20999327", "title": "Periarteritis nodosa complicating scarlet fever.", "content": "Periarteritis nodosa complicating scarlet fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999327"}
{"pmid": "20999328", "title": "Hemolytic disease of the newborn (erythroblastosis fetalis); treatment by a single massive transfusion, with complete recovery.", "content": "Hemolytic disease of the newborn (erythroblastosis fetalis); treatment by a single massive transfusion, with complete recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999328"}
{"pmid": "20999329", "title": "Acute hemolytic anemia associated with autoagglutination with a thermal amplitude of 0 to 37 C.", "content": "Acute hemolytic anemia associated with autoagglutination with a thermal amplitude of 0 to 37 C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999329"}
{"pmid": "20999330", "title": "Treatment of cryptococcic meningitis with penicillin.", "content": "Treatment of cryptococcic meningitis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999330"}
{"pmid": "20999331", "title": "Analgesic action of pethidine derivatives and related compounds.", "content": "Analgesic action of pethidine derivatives and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999331"}
{"pmid": "20999332", "title": "Chemotherapeutic action of dyes in typhus infection of mice.", "content": "Chemotherapeutic action of dyes in typhus infection of mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999332"}
{"pmid": "20999333", "title": "Amidines, guanidines and adrenaline inactivation in the liver.", "content": "Amidines, guanidines and adrenaline inactivation in the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999333"}
{"pmid": "20999334", "title": "Observations on the isolated phrenic nerve diaphragm preparation of the rat.", "content": "Observations on the isolated phrenic nerve diaphragm preparation of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999334"}
{"pmid": "20999335", "title": "The effect of ethanol, methanol, paraldehyde and acetone on the pressure of the cerebrospinal fluid of the dog.", "content": "The effect of ethanol, methanol, paraldehyde and acetone on the pressure of the cerebrospinal fluid of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999335"}
{"pmid": "20999336", "title": "Chemotherapeutic action of amidine and phenanthridinium compounds in T. congolense infections.", "content": "Chemotherapeutic action of amidine and phenanthridinium compounds in T. congolense infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999336"}
{"pmid": "20999337", "title": "The variation in the toxicity of phosgene for small animals with the duration of exposure.", "content": "The variation in the toxicity of phosgene for small animals with the duration of exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999337"}
{"pmid": "20999338", "title": "Synthetic substitutes for quinidine.", "content": "Synthetic substitutes for quinidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999338"}
{"pmid": "20999339", "title": "The assessment of analgesic activity in new synthetic drugs.", "content": "The assessment of analgesic activity in new synthetic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999339"}
{"pmid": "20999340", "title": "Methyl-thiouracil and thiouracil as antithyroid drugs.", "content": "Methyl-thiouracil and thiouracil as antithyroid drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999340"}
{"pmid": "20999341", "title": "Automatic apparatus for pharmacological assays on isolated preparations.", "content": "Automatic apparatus for pharmacological assays on isolated preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999341"}
{"pmid": "20999342", "title": "Sulphonamides in the treatment of caecal coccidiosis of chickens.", "content": "Sulphonamides in the treatment of caecal coccidiosis of chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999342"}
{"pmid": "20999345", "title": "The chemistry of some antibiotics.", "content": "The chemistry of some antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999345"}
{"pmid": "20999352", "title": "Synthetic detergents vs soap.", "content": "Synthetic detergents vs soap.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999352"}
{"pmid": "20999353", "title": "Chlorine dioxide for fat bleaching.", "content": "Chlorine dioxide for fat bleaching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999353"}
{"pmid": "20999354", "title": "Toxicity of DDT sprays to livestock.", "content": "Toxicity of DDT sprays to livestock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999354"}
{"pmid": "20999355", "title": "Toxicity of aerosols; rate of movement through and height of suspension in a toxic aerosol influences mortality of caged house flies.", "content": "Toxicity of aerosols; rate of movement through and height of suspension in a toxic aerosol influences mortality of caged house flies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999355"}
{"pmid": "20999356", "title": "Testing the germicidal activity of quaternary ammonium compounds.", "content": "Testing the germicidal activity of quaternary ammonium compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999356"}
{"pmid": "20999357", "title": "Sabadilla insecticide development.", "content": "Sabadilla insecticide development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999357"}
{"pmid": "20999365", "title": "Illumination standards.", "content": "Illumination standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999365"}
{"pmid": "20999367", "title": "Race relations in community health organization.", "content": "Race relations in community health organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999367"}
{"pmid": "20999366", "title": "Recent developments in murine typhus fever control.", "content": "Recent developments in murine typhus fever control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999366"}
{"pmid": "20999368", "title": "Health education program in Puerto Rico.", "content": "Health education program in Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999368"}
{"pmid": "20999369", "title": "Modern treatment of syphilis.", "content": "Modern treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999369"}
{"pmid": "20999370", "title": "Refrigeration in a food control program.", "content": "Refrigeration in a food control program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999370"}
{"pmid": "20999371", "title": "What good are health museums?", "content": "What good are health museums?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999371"}
{"pmid": "20999372", "title": "Gonococcus examinations; a comparison of slides, mailed slants and immediate plates.", "content": "Gonococcus examinations; a comparison of slides, mailed slants and immediate plates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999372"}
{"pmid": "20999373", "title": "Dangers associated with the use of living attenuated typhus vaccine.", "content": "Dangers associated with the use of living attenuated typhus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999373"}
{"pmid": "20999374", "title": "Place of the entomologist in public health.", "content": "Place of the entomologist in public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999374"}
{"pmid": "20999375", "title": "The use of chlorine dioxide in water treatment.", "content": "The use of chlorine dioxide in water treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999375"}
{"pmid": "20999427", "title": "Plan for encephalitis study.", "content": "Plan for encephalitis study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999427"}
{"pmid": "20999428", "title": "Public health aspects of industrial waste disposal.", "content": "Public health aspects of industrial waste disposal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999428"}
{"pmid": "20999429", "title": "STATE action to repress prostitution.", "content": "STATE action to repress prostitution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999429"}
{"pmid": "20999431", "title": "Health education in schools.", "content": "Health education in schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999431"}
{"pmid": "20999432", "title": "DIAGNOSIS of tuberculosis.", "content": "DIAGNOSIS of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999432"}
{"pmid": "20999433", "title": "Ringworm of the scalp.", "content": "Ringworm of the scalp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999433"}
{"pmid": "20999434", "title": "Allergy.", "content": "Allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999434"}
{"pmid": "20999435", "title": "Bronchial asthma.", "content": "Bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999435"}
{"pmid": "20999436", "title": "Tremendous increase in cancer of the lung; is tobacco a cause?", "content": "Tremendous increase in cancer of the lung; is tobacco a cause?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999436"}
{"pmid": "20999430", "title": "Flies, mosquitoes and DDT.", "content": "Flies, mosquitoes and DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999430"}
{"pmid": "20999437", "title": "Observations of a school nurse on the school health program.", "content": "Observations of a school nurse on the school health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999437"}
{"pmid": "20999438", "title": "A serious eye disease; glaucoma.", "content": "A serious eye disease; glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999438"}
{"pmid": "20999439", "title": "Hearing and hearing aids; the sense of hearing.", "content": "Hearing and hearing aids; the sense of hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999439"}
{"pmid": "20999440", "title": "Poliomyelitis.", "content": "Poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999440"}
{"pmid": "20999441", "title": "Cataract.", "content": "Cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999441"}
{"pmid": "20999442", "title": "CEREBRAL palsy cases getting more attention.", "content": "CEREBRAL palsy cases getting more attention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999442"}
{"pmid": "20999443", "title": "Opportunities for research in the School Health Service.", "content": "Opportunities for research in the School Health Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999443"}
{"pmid": "20999444", "title": "School meals and milk.", "content": "School meals and milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999444"}
{"pmid": "20999445", "title": "Syphilis in pregnancy: preliminary report on a Tyneside investigation.", "content": "Syphilis in pregnancy: preliminary report on a Tyneside investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999445"}
{"pmid": "20999447", "title": "Chemoprophylaxis of experimental influenza infections in eggs.", "content": "Chemoprophylaxis of experimental influenza infections in eggs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999447"}
{"pmid": "20999446", "title": "Typical structures on replicas of apparently intact tooth surfaces.", "content": "Typical structures on replicas of apparently intact tooth surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999446"}
{"pmid": "20999448", "title": "Separation of the complement-fixing agent from suspensions of yolk sac of chick embryo infected with the Karp strain of tsutsugamushi disease (scrub typhus).", "content": "Separation of the complement-fixing agent from suspensions of yolk sac of chick embryo infected with the Karp strain of tsutsugamushi disease (scrub typhus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999448"}
{"pmid": "20999449", "title": "A study of roder ectoparasites in Mobile, Ala.", "content": "A study of roder ectoparasites in Mobile, Ala.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999449"}
{"pmid": "20999450", "title": "CHANGES in regulations pertaining to tetraethyl lead gasoline.", "content": "CHANGES in regulations pertaining to tetraethyl lead gasoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999450"}
{"pmid": "20999451", "title": "Progress report on sulfide control research.", "content": "Progress report on sulfide control research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999451"}
{"pmid": "20999452", "title": "Fundamentals of biological oxidation clarification.", "content": "Fundamentals of biological oxidation clarification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999452"}
{"pmid": "20999453", "title": "Trickling filter treatment of sulfite waste liquor.", "content": "Trickling filter treatment of sulfite waste liquor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999453"}
{"pmid": "20999454", "title": "Stream pollution problems of the electroplating industry.", "content": "Stream pollution problems of the electroplating industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999454"}
{"pmid": "20999455", "title": "A method for accelerated equalization of industrial wastes.", "content": "A method for accelerated equalization of industrial wastes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999455"}
{"pmid": "20999456", "title": "SEWAGE treatment at military installations.", "content": "SEWAGE treatment at military installations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999456"}
{"pmid": "20999457", "title": "Endometrial vascular reactions and the mechanism of nidation.", "content": "Endometrial vascular reactions and the mechanism of nidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999457"}
{"pmid": "20999460", "title": "The effects of iron, copper, and thyroxine on the anemia induced by hypophysectomy in the adult female rat.", "content": "The effects of iron, copper, and thyroxine on the anemia induced by hypophysectomy in the adult female rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999460"}
{"pmid": "20999459", "title": "The effects of lactation on the postpartum involution of the uterus of the cat.", "content": "The effects of lactation on the postpartum involution of the uterus of the cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999459"}
{"pmid": "20999458", "title": "Effects of progesterone on the cells of the anterior hypophysis of the rat.", "content": "Effects of progesterone on the cells of the anterior hypophysis of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999458"}
{"pmid": "20999461", "title": "Testosterone-induced modifications of sex development in female hamsters.", "content": "Testosterone-induced modifications of sex development in female hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999461"}
{"pmid": "20999462", "title": "The action of thiourea on the intracellular colloid of the thyroid gland.", "content": "The action of thiourea on the intracellular colloid of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999462"}
{"pmid": "20999463", "title": "On the conical openings in the wall of venous sinusoids and their relations to the so-called erythrogenic capillaries in the bone marrow of man.", "content": "On the conical openings in the wall of venous sinusoids and their relations to the so-called erythrogenic capillaries in the bone marrow of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999463"}
{"pmid": "20999464", "title": "Embryonic and postnatal development of the adrenal cortex, particularly the zona glomerulosa and accessory nodules.", "content": "Embryonic and postnatal development of the adrenal cortex, particularly the zona glomerulosa and accessory nodules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999464"}
{"pmid": "20999465", "title": "A simian, deeply cleft, bilobed gall bladder with a Phrygian cap.", "content": "A simian, deeply cleft, bilobed gall bladder with a Phrygian cap.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999465"}
{"pmid": "20999466", "title": "Old and new concepts on the structure of dentin.", "content": "Old and new concepts on the structure of dentin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999466"}
{"pmid": "20999467", "title": "The arterial supply of the vermiform appendix.", "content": "The arterial supply of the vermiform appendix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999467"}
{"pmid": "20999468", "title": "Atrophy of the thyroid and hypertrophy of the adrenal in rats with alloxan diabetes.", "content": "Atrophy of the thyroid and hypertrophy of the adrenal in rats with alloxan diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999468"}
{"pmid": "20999469", "title": "The effect of alloxan diabetes on the Golgi apparatus and mitochondria of the thyroid gland in the rat.", "content": "The effect of alloxan diabetes on the Golgi apparatus and mitochondria of the thyroid gland in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999469"}
{"pmid": "20999470", "title": "A case of anomalous skeletal development in the foot.", "content": "A case of anomalous skeletal development in the foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999470"}
{"pmid": "20999471", "title": "Shadow casting; a technique to show surface texture in microscopical material.", "content": "Shadow casting; a technique to show surface texture in microscopical material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999471"}
{"pmid": "20999472", "title": "The histology of the preputial gland of the rat.", "content": "The histology of the preputial gland of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999472"}
{"pmid": "20999473", "title": "Protection against diabetes and production of hepatic necrosis by use of cysteine and alloxan in the rat.", "content": "Protection against diabetes and production of hepatic necrosis by use of cysteine and alloxan in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999473"}
{"pmid": "20999474", "title": "The cellular picture in the anterior pituitary of normal fowls from embryo to old age.", "content": "The cellular picture in the anterior pituitary of normal fowls from embryo to old age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999474"}
{"pmid": "20999475", "title": "Symposium on physiological contributions to war problems.", "content": "Symposium on physiological contributions to war problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999475"}
{"pmid": "20999476", "title": "High altitude problems in aviation.", "content": "High altitude problems in aviation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999476"}
{"pmid": "20999478", "title": "Clothing and heat exchanges.", "content": "Clothing and heat exchanges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999478"}
{"pmid": "20999477", "title": "Effects of acceleration in relation to aviation.", "content": "Effects of acceleration in relation to aviation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999477"}
{"pmid": "20999479", "title": "Problems of visual physiology during the war.", "content": "Problems of visual physiology during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999479"}
{"pmid": "20999480", "title": "Physiological contributions to the problem of shock.", "content": "Physiological contributions to the problem of shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999480"}
{"pmid": "20999482", "title": "Neurospora as a biochemical tool.", "content": "Neurospora as a biochemical tool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999482"}
{"pmid": "20999481", "title": "Symposium on some recent trends in Neurospora biochemistry.", "content": "Symposium on some recent trends in Neurospora biochemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999481"}
{"pmid": "20999483", "title": "The application of Neurospora to bioassay.", "content": "The application of Neurospora to bioassay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999483"}
{"pmid": "20999484", "title": "Adenine-requiring mutants of Neurospora crassa.", "content": "Adenine-requiring mutants of Neurospora crassa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999484"}
{"pmid": "20999485", "title": "Enzyme studies on a temperature-sensitive mutant of Neurospora.", "content": "Enzyme studies on a temperature-sensitive mutant of Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999485"}
{"pmid": "20999486", "title": "Altered sulfonamide antagonism in Neurospora.", "content": "Altered sulfonamide antagonism in Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999486"}
{"pmid": "20999487", "title": "Symposium on biochemistry of malarial parasites.", "content": "Symposium on biochemistry of malarial parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999487"}
{"pmid": "20999488", "title": "Chemical and nutritional observations on malarial parasites grown in vitro.", "content": "Chemical and nutritional observations on malarial parasites grown in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999488"}
{"pmid": "20999489", "title": "Metabolism of the malarial parasite; action of antimalarial agents upon separated Plasmodium lophurae and upon certain isolated enzyme systems.", "content": "Metabolism of the malarial parasite; action of antimalarial agents upon separated Plasmodium lophurae and upon certain isolated enzyme systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999489"}
{"pmid": "20999490", "title": "The influence of napthoquinones upon the respiratory and carbohydrate metabolism of malarial parasites.", "content": "The influence of napthoquinones upon the respiratory and carbohydrate metabolism of malarial parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999490"}
{"pmid": "20999492", "title": "Purposes and methods of the study.", "content": "Purposes and methods of the study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999492"}
{"pmid": "20999491", "title": "Survey of physiology in North America, 1945.", "content": "Survey of physiology in North America, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999491"}
{"pmid": "20999493", "title": "The identification and analysis of the North American population of physiologists.", "content": "The identification and analysis of the North American population of physiologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999493"}
{"pmid": "20999494", "title": "Economics.", "content": "Economics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999494"}
{"pmid": "20999495", "title": "The careers and incentives of physiologists.", "content": "The careers and incentives of physiologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999495"}
{"pmid": "20999496", "title": "Future physiology.", "content": "Future physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999496"}
{"pmid": "20999497", "title": "The action of magnesium on the heart.", "content": "The action of magnesium on the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999497"}
{"pmid": "20999498", "title": "Ruptured congenital aneurysm of the posterior sinus of Valsalva.", "content": "Ruptured congenital aneurysm of the posterior sinus of Valsalva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999498"}
{"pmid": "20999499", "title": "Healed dissecting aneurysm.", "content": "Healed dissecting aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999499"}
{"pmid": "20999500", "title": "Silent dissection of the aorta.", "content": "Silent dissection of the aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999500"}
{"pmid": "20999501", "title": "The genesis of the normal electrocardiogram.", "content": "The genesis of the normal electrocardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999501"}
{"pmid": "20999502", "title": "Heart-vector and leads.", "content": "Heart-vector and leads.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999502"}
{"pmid": "20999503", "title": "The heart in sternal depression.", "content": "The heart in sternal depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999503"}
{"pmid": "20999509", "title": "The collateral circulation of the human heart.", "content": "The collateral circulation of the human heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999509"}
{"pmid": "20999552", "title": "Penicillin in dental and oral surgery.", "content": "Penicillin in dental and oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999552"}
{"pmid": "20999553", "title": "The early diagnosis of cancer of the mouth.", "content": "The early diagnosis of cancer of the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999553"}
{"pmid": "20999554", "title": "A large dental cyst of the mandible.", "content": "A large dental cyst of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999554"}
{"pmid": "20999555", "title": "Orthodontic treatment by the public dental officer.", "content": "Orthodontic treatment by the public dental officer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999555"}
{"pmid": "20999556", "title": "The Kingsley splint; an obsolete piece of maxillo-facial equipment.", "content": "The Kingsley splint; an obsolete piece of maxillo-facial equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999556"}
{"pmid": "20999557", "title": "Building the amalgam restoration.", "content": "Building the amalgam restoration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999557"}
{"pmid": "20999558", "title": "The dentist looks at cancer of the lip.", "content": "The dentist looks at cancer of the lip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999558"}
{"pmid": "20999562", "title": "Some effects of dietary oxalate on the teeth of white rats.", "content": "Some effects of dietary oxalate on the teeth of white rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999562"}
{"pmid": "20999563", "title": "Depletion of hepatic reserves of vitamin A and carotene in cattle.", "content": "Depletion of hepatic reserves of vitamin A and carotene in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999563"}
{"pmid": "20999564", "title": "Riboflavin excretions of young women on diets containing varying levels of the B vitamins.", "content": "Riboflavin excretions of young women on diets containing varying levels of the B vitamins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999564"}
{"pmid": "20999566", "title": "The isoleucine, leucine and valine requirements of the chick.", "content": "The isoleucine, leucine and valine requirements of the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999566"}
{"pmid": "20999565", "title": "Thiamine excretions and blood levels of young women on diets containing varying levels of the B vitamins, with some observations on niacin and pantothenic acid.", "content": "Thiamine excretions and blood levels of young women on diets containing varying levels of the B vitamins, with some observations on niacin and pantothenic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999565"}
{"pmid": "20999567", "title": "The pantothenic acid content of the blood and tissues of the chicken as influenced by the level in the diet.", "content": "The pantothenic acid content of the blood and tissues of the chicken as influenced by the level in the diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999567"}
{"pmid": "20999568", "title": "The effects of a high fat diet in a temperate environment.", "content": "The effects of a high fat diet in a temperate environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999568"}
{"pmid": "20999559", "title": "A clinical study of sulphonamide dermatitis.", "content": "A clinical study of sulphonamide dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999559"}
{"pmid": "20999569", "title": "The effects of excess dietary calcium on longevity and tissue calcium in the albino rat.", "content": "The effects of excess dietary calcium on longevity and tissue calcium in the albino rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999569"}
{"pmid": "20999560", "title": "Inquiry into the social background of convicted women at Holloway Prison infected with venereal diseases.", "content": "Inquiry into the social background of convicted women at Holloway Prison infected with venereal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999560"}
{"pmid": "20999570", "title": "The retention of nutrients in cheese making; thiamine in Cheddar cheese made from raw and pasteurized milk.", "content": "The retention of nutrients in cheese making; thiamine in Cheddar cheese made from raw and pasteurized milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999570"}
{"pmid": "20999571", "title": "Reproductivity and growth of albino rats on a prolonged daily intake of caffeine.", "content": "Reproductivity and growth of albino rats on a prolonged daily intake of caffeine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999571"}
{"pmid": "20999572", "title": "Metabolism of women during the reproductive cycle; the utilization of thiamine during lactation.", "content": "Metabolism of women during the reproductive cycle; the utilization of thiamine during lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999572"}
{"pmid": "20999573", "title": "Metabolism of women during the reproductive cycle; the utilization of riboflavin during lactation.", "content": "Metabolism of women during the reproductive cycle; the utilization of riboflavin during lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999573"}
{"pmid": "20999561", "title": "A case of allergy to phenylhydrazine.", "content": "A case of allergy to phenylhydrazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999561"}
{"pmid": "20999574", "title": "Self selection of diet; appetite for B vitamins.", "content": "Self selection of diet; appetite for B vitamins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999574"}
{"pmid": "20999575", "title": "Self selection of diet; appetite for protein.", "content": "Self selection of diet; appetite for protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999575"}
{"pmid": "20999577", "title": "The nutritive value of the protein of varieties of legumes and the effect of methionine supplementation.", "content": "The nutritive value of the protein of varieties of legumes and the effect of methionine supplementation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999577"}
{"pmid": "20999576", "title": "Protein concentrates as amino acid sources for the chick; corn gluten meal, cottonseed meal and peanut meal.", "content": "Protein concentrates as amino acid sources for the chick; corn gluten meal, cottonseed meal and peanut meal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999576"}
{"pmid": "20999579", "title": "Evidence of citric acid synthesis in human subjects.", "content": "Evidence of citric acid synthesis in human subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999579"}
{"pmid": "20999578", "title": "Influence of a single dose of alpha tocopherol, administered to vitamin E deficient rats on the fifteenth day, upon subsequent growth.", "content": "Influence of a single dose of alpha tocopherol, administered to vitamin E deficient rats on the fifteenth day, upon subsequent growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999578"}
{"pmid": "20999580", "title": "The control of muscle spasm and arthritic pain through sympathetic block at the nasal ganglion and the use of the adenylic nucleotide.", "content": "The control of muscle spasm and arthritic pain through sympathetic block at the nasal ganglion and the use of the adenylic nucleotide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999580"}
{"pmid": "20999581", "title": "Physiological derangements in organic disease of the intestinal tract.", "content": "Physiological derangements in organic disease of the intestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999581"}
{"pmid": "20999582", "title": "Proctalgias and allied non-inflammatory perianal dyscrasias; coccygodynia proctalgia fugax, neurogenic pruritus ani.", "content": "Proctalgias and allied non-inflammatory perianal dyscrasias; coccygodynia proctalgia fugax, neurogenic pruritus ani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999582"}
{"pmid": "20999583", "title": "Pyrosis; an analysis of its clinical significance and pathogenesis.", "content": "Pyrosis; an analysis of its clinical significance and pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999583"}
{"pmid": "20999588", "title": "The hang-over in relation to the theory and treatment of alcohol addiction.", "content": "The hang-over in relation to the theory and treatment of alcohol addiction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999588"}
{"pmid": "20999589", "title": "Psychology and treatment of alcoholism.", "content": "Psychology and treatment of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999589"}
{"pmid": "20999590", "title": "Some practical observations of the treatment of problem drinkers.", "content": "Some practical observations of the treatment of problem drinkers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999590"}
{"pmid": "20999591", "title": "The medical profession and the problem of alcoholism.", "content": "The medical profession and the problem of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999591"}
{"pmid": "20999592", "title": "MONTAIGNE'S essay on drunkenness.", "content": "MONTAIGNE'S essay on drunkenness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999592"}
{"pmid": "20999584", "title": "Oral therapy in anogenital pruritus.", "content": "Oral therapy in anogenital pruritus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999584"}
{"pmid": "20999594", "title": "International action toward social security for seamen.", "content": "International action toward social security for seamen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999594"}
{"pmid": "20999595", "title": "Schistosomiasis japonica; its clinical development and recognition.", "content": "Schistosomiasis japonica; its clinical development and recognition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999595"}
{"pmid": "20999587", "title": "Intelligence, race, and age as selective factors in crime.", "content": "Intelligence, race, and age as selective factors in crime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999587"}
{"pmid": "20999596", "title": "Amebiasis of the liver; classification, diagnosis and treatment.", "content": "Amebiasis of the liver; classification, diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999596"}
{"pmid": "20999585", "title": "Hemorrhoids.", "content": "Hemorrhoids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999585"}
{"pmid": "20999597", "title": "Some common conditions, not due to primary heart disease, that may be associated with changes in the electrocardiogram.", "content": "Some common conditions, not due to primary heart disease, that may be associated with changes in the electrocardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999597"}
{"pmid": "20999598", "title": "Renal changes in secondary shock.", "content": "Renal changes in secondary shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999598"}
{"pmid": "20999599", "title": "Acute mediastinal emphysema.", "content": "Acute mediastinal emphysema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999599"}
{"pmid": "20999600", "title": "Studies on two sporadic cretinous brothers with goiter, together with some remarks on the relation of hyperplasia to neoplasia.", "content": "Studies on two sporadic cretinous brothers with goiter, together with some remarks on the relation of hyperplasia to neoplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999600"}
{"pmid": "20999601", "title": "An inquiry into the incidence of hyperhidrosis in convalescent trench foot.", "content": "An inquiry into the incidence of hyperhidrosis in convalescent trench foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999601"}
{"pmid": "20999586", "title": "Service in the armed forces and criminality.", "content": "Service in the armed forces and criminality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999586"}
{"pmid": "20999602", "title": "On the toxicity of the mercurial diuretics; observations on eighteen cases with suggestions for the prevention of toxic reactions.", "content": "On the toxicity of the mercurial diuretics; observations on eighteen cases with suggestions for the prevention of toxic reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999602"}
{"pmid": "20999603", "title": "Exfoliative dermatitis following penicillin therapy.", "content": "Exfoliative dermatitis following penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999603"}
{"pmid": "20999604", "title": "Acute syphilitic nephrosis.", "content": "Acute syphilitic nephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999604"}
{"pmid": "20999605", "title": "A case of agranulocytosis occurring during the course of penicillin therapy.", "content": "A case of agranulocytosis occurring during the course of penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999605"}
{"pmid": "20999606", "title": "Hypertension and the kidney.", "content": "Hypertension and the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999606"}
{"pmid": "20999607", "title": "RADIOACTIVE phosphorus as a therapeutic agent.", "content": "RADIOACTIVE phosphorus as a therapeutic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999607"}
{"pmid": "20999609", "title": "COMMISSION ON RESPIRATORY DISEASES. The transmission of primary atypical pneumonia to human volunteers; results of inoculation.", "content": "COMMISSION ON RESPIRATORY DISEASES. The transmission of primary atypical pneumonia to human volunteers; results of inoculation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999609"}
{"pmid": "20999608", "title": "COMMISSION ON RESPIRATORY DISEASES. The transmission of primary atypical pneumonia to human volunteers; experimental methods.", "content": "COMMISSION ON RESPIRATORY DISEASES. The transmission of primary atypical pneumonia to human volunteers; experimental methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999608"}
{"pmid": "20999610", "title": "COMMISSION ON RESPIRATORY DISEASES. The transmission of primary atypical pneumonia to human volunteers; clinical features.", "content": "COMMISSION ON RESPIRATORY DISEASES. The transmission of primary atypical pneumonia to human volunteers; clinical features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999610"}
{"pmid": "20999593", "title": "Characteristics of unit dust collectors.", "content": "Characteristics of unit dust collectors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999593"}
{"pmid": "20999611", "title": "COMMISSION ON RESPIRATORY DISEASES. The transmission of primary atypical pneumonia to human volunteers; laboratory studies.", "content": "COMMISSION ON RESPIRATORY DISEASES. The transmission of primary atypical pneumonia to human volunteers; laboratory studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999611"}
{"pmid": "20999612", "title": "The effect of the method of administration on the therapeutic efficacy of sodium penicillin in experimental syphilis.", "content": "The effect of the method of administration on the therapeutic efficacy of sodium penicillin in experimental syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999612"}
{"pmid": "20999613", "title": "Perfectionism in medicine.", "content": "Perfectionism in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999613"}
{"pmid": "20999614", "title": "[Electrocardiogram] a letter to the Editor.", "content": "[Electrocardiogram] a letter to the Editor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999614"}
{"pmid": "20999615", "title": "Coronaries; coronary arteriosclerosis with special reference to its etiology and pathogenesis.", "content": "Coronaries; coronary arteriosclerosis with special reference to its etiology and pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999615"}
{"pmid": "20999617", "title": "Technique and interpretation of lower extremity venograms.", "content": "Technique and interpretation of lower extremity venograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999617"}
{"pmid": "20999616", "title": "Clubbing of fingers in a case of ascites.", "content": "Clubbing of fingers in a case of ascites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999616"}
{"pmid": "20999618", "title": "Hypoparathyroidism.", "content": "Hypoparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999618"}
{"pmid": "20999619", "title": "Use of the anti-coagulants, heparin and dicumarol.", "content": "Use of the anti-coagulants, heparin and dicumarol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999619"}
{"pmid": "20999620", "title": "Prepayment and the future of American medicine.", "content": "Prepayment and the future of American medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999620"}
{"pmid": "20999621", "title": "What the war taught about amputations.", "content": "What the war taught about amputations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999621"}
{"pmid": "20999622", "title": "Maternal, fetal and neonatal mortality.", "content": "Maternal, fetal and neonatal mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999622"}
{"pmid": "20999623", "title": "Pyelitis of pregnancy.", "content": "Pyelitis of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999623"}
{"pmid": "20999624", "title": "[Histoplasmosis].", "content": "[Histoplasmosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999624"}
{"pmid": "20999625", "title": "Anesthesia for emergency surgical procedures.", "content": "Anesthesia for emergency surgical procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999625"}
{"pmid": "20999626", "title": "Treatment of bladder tumors.", "content": "Treatment of bladder tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999626"}
{"pmid": "20999627", "title": "The onset of ovulation during the puerperium.", "content": "The onset of ovulation during the puerperium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999627"}
{"pmid": "20999628", "title": "The use of penicillin in non-gonococcal infections of the urogenital tract.", "content": "The use of penicillin in non-gonococcal infections of the urogenital tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999628"}
{"pmid": "20999629", "title": "The trend of medicine and its relationship to the prevention of disease.", "content": "The trend of medicine and its relationship to the prevention of disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999629"}
{"pmid": "20999630", "title": "The clotting mechanism and tests for its efficiency.", "content": "The clotting mechanism and tests for its efficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999630"}
{"pmid": "20999632", "title": "The Rh factor in clinical obstetrics.", "content": "The Rh factor in clinical obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999632"}
{"pmid": "20999631", "title": "Delayed reactions following penicillin therapy.", "content": "Delayed reactions following penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999631"}
{"pmid": "20999633", "title": "Court holds C. P. S. not subject to insurance laws.", "content": "Court holds C. P. S. not subject to insurance laws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999633"}
{"pmid": "20999634", "title": "The sensitivity of bacteria to the action of penicillin.", "content": "The sensitivity of bacteria to the action of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999634"}
{"pmid": "20999635", "title": "Wartime advances in medicine which might be translated into civil practice.", "content": "Wartime advances in medicine which might be translated into civil practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999635"}
{"pmid": "20999636", "title": "The problem of bacterial variability and the origin of infectious disease.", "content": "The problem of bacterial variability and the origin of infectious disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999636"}
{"pmid": "20999637", "title": "Rheumatic encephalopathy.", "content": "Rheumatic encephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999637"}
{"pmid": "20999638", "title": "A case of blackwater fever observed in Britain.", "content": "A case of blackwater fever observed in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999638"}
{"pmid": "20999644", "title": "The preparation of an antigen from Kedrowsky's bacillus for the complement-fixation test for kalaazar.", "content": "The preparation of an antigen from Kedrowsky's bacillus for the complement-fixation test for kalaazar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999644"}
{"pmid": "20999647", "title": "The rate of absorption of different fats and oils.", "content": "The rate of absorption of different fats and oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999647"}
{"pmid": "20999645", "title": "Vitamin A and carotene content of ghee (clarified butter) and fortified margarine.", "content": "Vitamin A and carotene content of ghee (clarified butter) and fortified margarine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999645"}
{"pmid": "20999646", "title": "The digestibility of certain vegetable oils and fats determined by metabolic experiments on human beings.", "content": "The digestibility of certain vegetable oils and fats determined by metabolic experiments on human beings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999646"}
{"pmid": "20999649", "title": "Destruction of vitamin B1 of some vegetables during cooking and the effect of cooking on free and combined vitamin B1 of some foodstuffs.", "content": "Destruction of vitamin B1 of some vegetables during cooking and the effect of cooking on free and combined vitamin B1 of some foodstuffs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999649"}
{"pmid": "20999648", "title": "The effect of different fats on calcium utilization in human beings.", "content": "The effect of different fats on calcium utilization in human beings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999648"}
{"pmid": "20999650", "title": "Comparative value of butter-fats and vegetable oils for growth.", "content": "Comparative value of butter-fats and vegetable oils for growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999650"}
{"pmid": "20999652", "title": "The absorption of fats from the human intestine.", "content": "The absorption of fats from the human intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999652"}
{"pmid": "20999651", "title": "The effects on growth in rats of butter and ragi (Eleusine coracana), separately and combined, as supplements to the poor rice diet of South India.", "content": "The effects on growth in rats of butter and ragi (Eleusine coracana), separately and combined, as supplements to the poor rice diet of South India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999651"}
{"pmid": "20999653", "title": "Observations on the carotenoid pigments of local varieties of yellow maize.", "content": "Observations on the carotenoid pigments of local varieties of yellow maize.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999653"}
{"pmid": "20999639", "title": "General principles of pharmacology.", "content": "General principles of pharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999639"}
{"pmid": "20999654", "title": "Observations on the carotenoid pigments of the mango fruit.", "content": "Observations on the carotenoid pigments of the mango fruit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999654"}
{"pmid": "20999643", "title": "Functions of a psychiatric social worker.", "content": "Functions of a psychiatric social worker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999643"}
{"pmid": "20999655", "title": "Observations on the vitamin A content of buffalo butter-fat (ghee); effect of the method of preparation, storage and cooking.", "content": "Observations on the vitamin A content of buffalo butter-fat (ghee); effect of the method of preparation, storage and cooking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999655"}
{"pmid": "20999640", "title": "Aversion treatment of alcoholism.", "content": "Aversion treatment of alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999640"}
{"pmid": "20999641", "title": "An analysis of the Queen's Hospital Diabetic Clinic.", "content": "An analysis of the Queen's Hospital Diabetic Clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999641"}
{"pmid": "20999656", "title": "The effect of herperidin and a factor in Bengal gram (Cicer arietinum) on the growth of guinea-pigs.", "content": "The effect of herperidin and a factor in Bengal gram (Cicer arietinum) on the growth of guinea-pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999656"}
{"pmid": "20999657", "title": "Studies on the destruction of vitamin A in shark-liver oil; some factors affecting the stability.", "content": "Studies on the destruction of vitamin A in shark-liver oil; some factors affecting the stability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999657"}
{"pmid": "20999658", "title": "Fluorine and dental caries in India.", "content": "Fluorine and dental caries in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999658"}
{"pmid": "20999642", "title": "Erythroblastosis fetalis and icterus praecox.", "content": "Erythroblastosis fetalis and icterus praecox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999642"}
{"pmid": "20999659", "title": "Eruption age of the teeth in India.", "content": "Eruption age of the teeth in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999659"}
{"pmid": "20999660", "title": "Anaemia and malnutrition in Indian Army recruits.", "content": "Anaemia and malnutrition in Indian Army recruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999660"}
{"pmid": "20999661", "title": "A feeding experiment among Indian Army recruits.", "content": "A feeding experiment among Indian Army recruits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999661"}
{"pmid": "20999662", "title": "A preliminary study of the biochemical changes in starvation cases.", "content": "A preliminary study of the biochemical changes in starvation cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999662"}
{"pmid": "20999663", "title": "Studies on the biochemistry of the cholera-red reaction.", "content": "Studies on the biochemistry of the cholera-red reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999663"}
{"pmid": "20999664", "title": "Studies on carbohydrate metabolism.", "content": "Studies on carbohydrate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999664"}
{"pmid": "20999665", "title": "Statistical studies in glucose tolerance; blood glucose of normal male subjects.", "content": "Statistical studies in glucose tolerance; blood glucose of normal male subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999665"}
{"pmid": "20999666", "title": "Pharmacological action of an active constituent isolated from Daemia estensa Linn. (Syn. Pergularia extensa).", "content": "Pharmacological action of an active constituent isolated from Daemia estensa Linn. (Syn. Pergularia extensa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999666"}
{"pmid": "20999667", "title": "Section of the hypothalamus to remove the hyperglycaemic effect of urethane.", "content": "Section of the hypothalamus to remove the hyperglycaemic effect of urethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999667"}
{"pmid": "20999668", "title": "The comparative action of some alkyl hydrocupreidines.", "content": "The comparative action of some alkyl hydrocupreidines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999668"}
{"pmid": "20999669", "title": "Studies on coagulation of blood.", "content": "Studies on coagulation of blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999669"}
{"pmid": "20999670", "title": "Exposure of blood vessels.", "content": "Exposure of blood vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999670"}
{"pmid": "20999671", "title": "Orthopaedia MCMXLVI.", "content": "Orthopaedia MCMXLVI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999671"}
{"pmid": "20999672", "title": "Virus diseases of the nervous system.", "content": "Virus diseases of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999672"}
{"pmid": "20999673", "title": "Today's treatment of syphilis.", "content": "Today's treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999673"}
{"pmid": "20999674", "title": "Hemophilus influenzae meningitis treated with streptomycin.", "content": "Hemophilus influenzae meningitis treated with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999674"}
{"pmid": "20999675", "title": "Dislocations.", "content": "Dislocations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999675"}
{"pmid": "20999676", "title": "Ectopic endometrial tissue in the thigh.", "content": "Ectopic endometrial tissue in the thigh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999676"}
{"pmid": "20999677", "title": "Pancreatic calculi with associated diabetes mellitus.", "content": "Pancreatic calculi with associated diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999677"}
{"pmid": "20999678", "title": "Chronic brucellosis as a public health problem.", "content": "Chronic brucellosis as a public health problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999678"}
{"pmid": "20999679", "title": "Chronic brucellosis.", "content": "Chronic brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999679"}
{"pmid": "20999681", "title": "The practice of medicine in rural areas.", "content": "The practice of medicine in rural areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999681"}
{"pmid": "20999680", "title": "Symptomatology and diagnosis of chronic brucellosis.", "content": "Symptomatology and diagnosis of chronic brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999680"}
{"pmid": "20999682", "title": "The general practitioner in a public health program.", "content": "The general practitioner in a public health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999682"}
{"pmid": "20999683", "title": "Treatment of peptic ulcer in the diabetic.", "content": "Treatment of peptic ulcer in the diabetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999683"}
{"pmid": "20999684", "title": "The office practice of the general practitioner.", "content": "The office practice of the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999684"}
{"pmid": "20999685", "title": "Family physician: a reminiscence.", "content": "Family physician: a reminiscence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999685"}
{"pmid": "20999686", "title": "Hazards in the utilization of metallic external skeletal fixation in the treatment of fractures.", "content": "Hazards in the utilization of metallic external skeletal fixation in the treatment of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999686"}
{"pmid": "20999687", "title": "Pancreatic lithiasis.", "content": "Pancreatic lithiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999687"}
{"pmid": "20999688", "title": "Pre- and post-operative parenteral therapy.", "content": "Pre- and post-operative parenteral therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999688"}
{"pmid": "20999690", "title": "Paracolon bacilli and their relation to urinary tract infections.", "content": "Paracolon bacilli and their relation to urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999690"}
{"pmid": "20999689", "title": "The experimental production of generalized arteritis and periarteritis (periarteritis nodosa).", "content": "The experimental production of generalized arteritis and periarteritis (periarteritis nodosa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999689"}
{"pmid": "20999691", "title": "Conjoined action of penicillin and bacteriophages.", "content": "Conjoined action of penicillin and bacteriophages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999691"}
{"pmid": "20999692", "title": "The interpretation of the Weil-Felix agglutination test in Rocky Mountain spotted fever.", "content": "The interpretation of the Weil-Felix agglutination test in Rocky Mountain spotted fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999692"}
{"pmid": "20999693", "title": "Sulfonamides and dark adaptation.", "content": "Sulfonamides and dark adaptation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999693"}
{"pmid": "20999694", "title": "Liver function tests in neurosyphilitic patients with induced vivax malaria of Pacific and Mediterranean origin.", "content": "Liver function tests in neurosyphilitic patients with induced vivax malaria of Pacific and Mediterranean origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999694"}
{"pmid": "20999696", "title": "The production and course of alloxan diabetes in the rat.", "content": "The production and course of alloxan diabetes in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999696"}
{"pmid": "20999695", "title": "Studies of pancreatic function; the effect of ligation of the pancreatic ducts upon the amylase and lipidase content of the blood.", "content": "Studies of pancreatic function; the effect of ligation of the pancreatic ducts upon the amylase and lipidase content of the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999695"}
{"pmid": "20999697", "title": "The use of heparin when performing exchange blood transfusions in newborn infants.", "content": "The use of heparin when performing exchange blood transfusions in newborn infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999697"}
{"pmid": "20999698", "title": "Permeability of the human placenta to isoantibodies.", "content": "Permeability of the human placenta to isoantibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999698"}
{"pmid": "20999699", "title": "The quantitative determination of a pepsin-like substance in the urine of normal individuals and of patients with pernicious anemia.", "content": "The quantitative determination of a pepsin-like substance in the urine of normal individuals and of patients with pernicious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999699"}
{"pmid": "20999700", "title": "Hemochromatosis; review of literature and presentation of a case without pigmentation or diabetes.", "content": "Hemochromatosis; review of literature and presentation of a case without pigmentation or diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999700"}
{"pmid": "20999701", "title": "A simple method for performing a Wassermann test on anticomplementary serum.", "content": "A simple method for performing a Wassermann test on anticomplementary serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999701"}
{"pmid": "20999702", "title": "A mechanical device to facilitate electrocardiographic reading.", "content": "A mechanical device to facilitate electrocardiographic reading.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999702"}
{"pmid": "20999703", "title": "An electrocardiographic caliper calculator.", "content": "An electrocardiographic caliper calculator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999703"}
{"pmid": "20999704", "title": "The determination of urine urobilinogen; the interpretation of the rate of color development of the Ehrlich reaction.", "content": "The determination of urine urobilinogen; the interpretation of the rate of color development of the Ehrlich reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999704"}
{"pmid": "20999705", "title": "Early diagnosis of brain tumors.", "content": "Early diagnosis of brain tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999705"}
{"pmid": "20999707", "title": "The treatment of whooping cough.", "content": "The treatment of whooping cough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999707"}
{"pmid": "20999706", "title": "Rheumatic heart disease in children.", "content": "Rheumatic heart disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999706"}
{"pmid": "20999708", "title": "Congenital cardiovascular malformations; discussion of some of the more common types.", "content": "Congenital cardiovascular malformations; discussion of some of the more common types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999708"}
{"pmid": "20999709", "title": "The practical diagnosis of congenital heart lesions amenable to treatment.", "content": "The practical diagnosis of congenital heart lesions amenable to treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999709"}
{"pmid": "20999710", "title": "Simplified management of relative sterility.", "content": "Simplified management of relative sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999710"}
{"pmid": "20999711", "title": "Early rising after major surgery.", "content": "Early rising after major surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999711"}
{"pmid": "20999712", "title": "ROCKY MOUNTAIN spotted fever in Georgia.", "content": "ROCKY MOUNTAIN spotted fever in Georgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999712"}
{"pmid": "20999713", "title": "The new field for nurses.", "content": "The new field for nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999713"}
{"pmid": "20999721", "title": "The clinical and pathological features of the dysenteries.", "content": "The clinical and pathological features of the dysenteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999721"}
{"pmid": "20999722", "title": "Interstitial neuritis and the pressure theory of pain; a critical review and a reflex hypothesis.", "content": "Interstitial neuritis and the pressure theory of pain; a critical review and a reflex hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999722"}
{"pmid": "20999724", "title": "A report on the psychopathic states of the Australian Imperial Force in the Malayan Campaign.", "content": "A report on the psychopathic states of the Australian Imperial Force in the Malayan Campaign.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999724"}
{"pmid": "20999723", "title": "The influence of anaesthetics on the content of deaminating enzyme in human plasma.", "content": "The influence of anaesthetics on the content of deaminating enzyme in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999723"}
{"pmid": "20999714", "title": "On the influence of stilbamidine upon multiple myeloma.", "content": "On the influence of stilbamidine upon multiple myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999714"}
{"pmid": "20999725", "title": "Some problems of backache and sciatica.", "content": "Some problems of backache and sciatica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999725"}
{"pmid": "20999717", "title": "Spontaneous pneumothorax.", "content": "Spontaneous pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999717"}
{"pmid": "20999727", "title": "Renal dwarfism.", "content": "Renal dwarfism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999727"}
{"pmid": "20999726", "title": "A mixed tumour of the palate with sarcomatous changes.", "content": "A mixed tumour of the palate with sarcomatous changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999726"}
{"pmid": "20999715", "title": "Primary pulmonary carcinoma.", "content": "Primary pulmonary carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999715"}
{"pmid": "20999716", "title": "Cervico-mediastinal infection.", "content": "Cervico-mediastinal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999716"}
{"pmid": "20999719", "title": "Spontaneous recovery from subacute bacterial endocarditis in interventricular septal defect.", "content": "Spontaneous recovery from subacute bacterial endocarditis in interventricular septal defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999719"}
{"pmid": "20999728", "title": "Bilateral compound fracture of the tibia and fibula.", "content": "Bilateral compound fracture of the tibia and fibula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999728"}
{"pmid": "20999729", "title": "Junctional disorder sequent to organic disease.", "content": "Junctional disorder sequent to organic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999729"}
{"pmid": "20999730", "title": "The typing of Bacterium typhosum.", "content": "The typing of Bacterium typhosum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999730"}
{"pmid": "20999731", "title": "A quarter-century of paediatrics; gastro-enteritis.", "content": "A quarter-century of paediatrics; gastro-enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999731"}
{"pmid": "20999732", "title": "A quarter-century of paediatrics; juvenile lead poisoning.", "content": "A quarter-century of paediatrics; juvenile lead poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999732"}
{"pmid": "20999718", "title": "Liver abscess with perforation into lung.", "content": "Liver abscess with perforation into lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999718"}
{"pmid": "20999720", "title": "Essays on the biology of disease; Libman-Sacks disease.", "content": "Essays on the biology of disease; Libman-Sacks disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999720"}
{"pmid": "20999735", "title": "The sex life of the adolescent.", "content": "The sex life of the adolescent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999735"}
{"pmid": "20999734", "title": "Sexual problems of childhood and adolescence.", "content": "Sexual problems of childhood and adolescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999734"}
{"pmid": "20999733", "title": "A quarter-century of paediatrics; acute osteomyelitis.", "content": "A quarter-century of paediatrics; acute osteomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999733"}
{"pmid": "20999736", "title": "Adenocarcinoma of the colon with obstruction.", "content": "Adenocarcinoma of the colon with obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999736"}
{"pmid": "20999737", "title": "Present concepts of the etiology of rheumatic fever.", "content": "Present concepts of the etiology of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999737"}
{"pmid": "20999739", "title": "Plan adopted by cancer clinic for treatment of tumors of the breast.", "content": "Plan adopted by cancer clinic for treatment of tumors of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999739"}
{"pmid": "20999738", "title": "Skeletal manifestations of Gaucher's disease.", "content": "Skeletal manifestations of Gaucher's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999738"}
{"pmid": "20999740", "title": "Cancer of the bladder and urinary tract.", "content": "Cancer of the bladder and urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999740"}
{"pmid": "20999741", "title": "Tularemia treated with streptomycin sulfate.", "content": "Tularemia treated with streptomycin sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999741"}
{"pmid": "20999742", "title": "Acute trachoma treated with sulfanilamide.", "content": "Acute trachoma treated with sulfanilamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999742"}
{"pmid": "20999743", "title": "Anesthesia for sympathectomy in hypertension.", "content": "Anesthesia for sympathectomy in hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999743"}
{"pmid": "20999744", "title": "Aids in thoracic surgery.", "content": "Aids in thoracic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999744"}
{"pmid": "20999745", "title": "The use of ozonides in dermatology.", "content": "The use of ozonides in dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999745"}
{"pmid": "20999746", "title": "The treatment of experimental syphilis with penicillin.", "content": "The treatment of experimental syphilis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999746"}
{"pmid": "20999747", "title": "Pigmentary changes in the skin in the Negro.", "content": "Pigmentary changes in the skin in the Negro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999747"}
{"pmid": "20999748", "title": "Report on an outbreak of endemic febrile illness, not yet identified, occurring in New York City.", "content": "Report on an outbreak of endemic febrile illness, not yet identified, occurring in New York City.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999748"}
{"pmid": "20999749", "title": "Neurodermatitis and occupational dermatitis.", "content": "Neurodermatitis and occupational dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999749"}
{"pmid": "20999750", "title": "Results of treatment of psychoneuroses by the general practitioner.", "content": "Results of treatment of psychoneuroses by the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999750"}
{"pmid": "20999751", "title": "Multiple platelet thrombi.", "content": "Multiple platelet thrombi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999751"}
{"pmid": "20999752", "title": "Synergistic action of digitalis and quinidine.", "content": "Synergistic action of digitalis and quinidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999752"}
{"pmid": "20999753", "title": "Streptomycin treatment of intractable ulcerative colitis.", "content": "Streptomycin treatment of intractable ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999753"}
{"pmid": "20999754", "title": "INCOMES of general practitioners in the United Kingdom.", "content": "INCOMES of general practitioners in the United Kingdom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999754"}
{"pmid": "20999755", "title": "Some observations on nonspecific abdominal lymphadenitis.", "content": "Some observations on nonspecific abdominal lymphadenitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999755"}
{"pmid": "20999756", "title": "Who owns the x-ray film?", "content": "Who owns the x-ray film?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999756"}
{"pmid": "20999757", "title": "Interstitial cystitis.", "content": "Interstitial cystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999757"}
{"pmid": "20999758", "title": "A review of cases since August, 1940, with special reference to certain atresias of the new-born.", "content": "A review of cases since August, 1940, with special reference to certain atresias of the new-born.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999758"}
{"pmid": "20999759", "title": "Carbon tetrachloride poisoning.", "content": "Carbon tetrachloride poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999759"}
{"pmid": "20999760", "title": "Vitamin B deficiency in ex-prisoners of war from Japan.", "content": "Vitamin B deficiency in ex-prisoners of war from Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999760"}
{"pmid": "20999761", "title": "Tetanus with pentothal as narcotic.", "content": "Tetanus with pentothal as narcotic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999761"}
{"pmid": "20999762", "title": "Human coccidiosis.", "content": "Human coccidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999762"}
{"pmid": "20999764", "title": "The thyroid gland and recent research.", "content": "The thyroid gland and recent research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999764"}
{"pmid": "20999763", "title": "Tetanus neonatorum in New Zealand.", "content": "Tetanus neonatorum in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999763"}
{"pmid": "20999765", "title": "The electrocardiogram in coronary disease.", "content": "The electrocardiogram in coronary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999765"}
{"pmid": "20999766", "title": "The recognition of pituitary tumours in general practice, with some remarks on treatment.", "content": "The recognition of pituitary tumours in general practice, with some remarks on treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999766"}
{"pmid": "20999767", "title": "Blood transfusion in the Army; its application to civil practice.", "content": "Blood transfusion in the Army; its application to civil practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999767"}
{"pmid": "20999768", "title": "Stilboestrol in the management of carcinoma of the prostate.", "content": "Stilboestrol in the management of carcinoma of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999768"}
{"pmid": "20999769", "title": "Pilonidal sinus.", "content": "Pilonidal sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999769"}
{"pmid": "20999770", "title": "Pitfalls in diagnosis and treatment of cancer.", "content": "Pitfalls in diagnosis and treatment of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999770"}
{"pmid": "20999771", "title": "Pitfalls in cancer management.", "content": "Pitfalls in cancer management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999771"}
{"pmid": "20999772", "title": "Pitfalls in cancer diagnosis and treatment.", "content": "Pitfalls in cancer diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999772"}
{"pmid": "20999773", "title": "Pelvimetry.", "content": "Pelvimetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999773"}
{"pmid": "20999774", "title": "The roentgen examination of the male urethra.", "content": "The roentgen examination of the male urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999774"}
{"pmid": "20999775", "title": "The physical service to radiology in New Zealand.", "content": "The physical service to radiology in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999775"}
{"pmid": "20999776", "title": "The obstetrical causes of still-births and neonatal deaths.", "content": "The obstetrical causes of still-births and neonatal deaths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999776"}
{"pmid": "20999778", "title": "Group practice.", "content": "Group practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999778"}
{"pmid": "20999777", "title": "The treatment of toxaemia of pregnancy.", "content": "The treatment of toxaemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999777"}
{"pmid": "20999779", "title": "The hysterogram in uterine bleeding.", "content": "The hysterogram in uterine bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999779"}
{"pmid": "20999780", "title": "Habit training in infancy.", "content": "Habit training in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999780"}
{"pmid": "20999781", "title": "Changes in the Parkinsonian syndrome in the Twentieth Century.", "content": "Changes in the Parkinsonian syndrome in the Twentieth Century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999781"}
{"pmid": "20999783", "title": "The epidemiology of the 1945 outbreak of poliomyelitis in Mauritius.", "content": "The epidemiology of the 1945 outbreak of poliomyelitis in Mauritius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999783"}
{"pmid": "20999784", "title": "The ocular manifestations of tuberose sclerosis.", "content": "The ocular manifestations of tuberose sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999784"}
{"pmid": "20999785", "title": "The estimation of prostatic phosphatase in serum and its use in the diagnosis of prostatic carcinoma.", "content": "The estimation of prostatic phosphatase in serum and its use in the diagnosis of prostatic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999785"}
{"pmid": "20999782", "title": "Craniofacial dysostosis; the significance of ocular hypertelorism.", "content": "Craniofacial dysostosis; the significance of ocular hypertelorism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999782"}
{"pmid": "20999800", "title": "Neuropsychiatric problems of returning servicemen.", "content": "Neuropsychiatric problems of returning servicemen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999800"}
{"pmid": "20999801", "title": "Primary atypical pneumonia with a report of sixty cases.", "content": "Primary atypical pneumonia with a report of sixty cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999801"}
{"pmid": "20999802", "title": "Jaundice in the newborn infant.", "content": "Jaundice in the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999802"}
{"pmid": "20999803", "title": "The prevention of syphilis in the newborn.", "content": "The prevention of syphilis in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999803"}
{"pmid": "20999804", "title": "Frog test (Xenopus laevis) for pregnancy.", "content": "Frog test (Xenopus laevis) for pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999804"}
{"pmid": "20999805", "title": "Interstitial irradiation therapy in carcinoma originating at the limbus; report of two cases treated with radium element seeds.", "content": "Interstitial irradiation therapy in carcinoma originating at the limbus; report of two cases treated with radium element seeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999805"}
{"pmid": "20999806", "title": "Etiology of otomycosis.", "content": "Etiology of otomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999806"}
{"pmid": "20999807", "title": "External otitis.", "content": "External otitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999807"}
{"pmid": "20999808", "title": "Malaria control in China.", "content": "Malaria control in China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999808"}
{"pmid": "20999809", "title": "Relapsing and recurring meningitis.", "content": "Relapsing and recurring meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999809"}
{"pmid": "20999811", "title": "The relation of the medical staff to the hospital.", "content": "The relation of the medical staff to the hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999811"}
{"pmid": "20999810", "title": "A case of Morton's metatarsalgia (Morton's toe) treated by operation.", "content": "A case of Morton's metatarsalgia (Morton's toe) treated by operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999810"}
{"pmid": "20999813", "title": "A series of B. L. A. eye casualties.", "content": "A series of B. L. A. eye casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999813"}
{"pmid": "20999812", "title": "The treatment of early syphilis in the Army.", "content": "The treatment of early syphilis in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999812"}
{"pmid": "20999814", "title": "Malnutrition and chronic sepsis.", "content": "Malnutrition and chronic sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999814"}
{"pmid": "20999815", "title": "The scope of morbid anatomy in the Army Medical Services.", "content": "The scope of morbid anatomy in the Army Medical Services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999815"}
{"pmid": "20999816", "title": "Glandular fever, B. A. O. R., 1945.", "content": "Glandular fever, B. A. O. R., 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999816"}
{"pmid": "20999817", "title": "Endemic diarrhoea.", "content": "Endemic diarrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999817"}
{"pmid": "20999818", "title": "A remarkable case of mediastinal neoplasm.", "content": "A remarkable case of mediastinal neoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999818"}
{"pmid": "20999819", "title": "A penicillin injector.", "content": "A penicillin injector.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999819"}
{"pmid": "20999820", "title": "Effect of dilution on fertilizing capacity of rabbit spermatozoa.", "content": "Effect of dilution on fertilizing capacity of rabbit spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999820"}
{"pmid": "20999821", "title": "Rapid production of acute disseminated encephalomyelitis in rhesus monkeys by injection of brain tissue with adjuvants.", "content": "Rapid production of acute disseminated encephalomyelitis in rhesus monkeys by injection of brain tissue with adjuvants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999821"}
{"pmid": "20999822", "title": "Plant carbonic anhydrase.", "content": "Plant carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999822"}
{"pmid": "20999823", "title": "The differentiation of penicillins G and K by an assay method in vivo.", "content": "The differentiation of penicillins G and K by an assay method in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999823"}
{"pmid": "20999825", "title": "A high-capacity sensitive relay.", "content": "A high-capacity sensitive relay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999825"}
{"pmid": "20999824", "title": "Apparatus for the prolonged sterile culture in vitro of whole plants or excised plant tissues.", "content": "Apparatus for the prolonged sterile culture in vitro of whole plants or excised plant tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999824"}
{"pmid": "20999826", "title": "A punched-card technique for computing means, standard deviations, and the product-moment correlation coefficient and for listing scattergrams.", "content": "A punched-card technique for computing means, standard deviations, and the product-moment correlation coefficient and for listing scattergrams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999826"}
{"pmid": "20999827", "title": "Plastic cages for insects.", "content": "Plastic cages for insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999827"}
{"pmid": "20999828", "title": "On tobacco smoke.", "content": "On tobacco smoke.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999828"}
{"pmid": "20999829", "title": "Properties of a virus inactivator from yeast.", "content": "Properties of a virus inactivator from yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999829"}
{"pmid": "20999830", "title": "Pretraumatic personality and psychiatric sequelae of head injury; correlation multiple, specific factors in the pretraumatic personality and psychiatric reaction to head injury, based on analysis of one hundred and one cases.", "content": "Pretraumatic personality and psychiatric sequelae of head injury; correlation multiple, specific factors in the pretraumatic personality and psychiatric reaction to head injury, based on analysis of one hundred and one cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999830"}
{"pmid": "20999831", "title": "Effects of denervation on fasciculations in human muscle; relation of fibrillations to fasciculations.", "content": "Effects of denervation on fasciculations in human muscle; relation of fibrillations to fasciculations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999831"}
{"pmid": "20999832", "title": "Toxicity of quinacrine (atabrine) for the central nervous system; an experimental study on human subjects.", "content": "Toxicity of quinacrine (atabrine) for the central nervous system; an experimental study on human subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999832"}
{"pmid": "20999833", "title": "Ring scotoma and tubular fields; their significance in cases of head injury.", "content": "Ring scotoma and tubular fields; their significance in cases of head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999833"}
{"pmid": "20999834", "title": "Camptocormia.", "content": "Camptocormia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999834"}
{"pmid": "20999835", "title": "Neurinoma of the twelfth nerve.", "content": "Neurinoma of the twelfth nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999835"}
{"pmid": "20999836", "title": "Cerebral thromboangitis obliterans.", "content": "Cerebral thromboangitis obliterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999836"}
{"pmid": "20999837", "title": "Contractures following experimentally produced lesions of the peripheral nerves.", "content": "Contractures following experimentally produced lesions of the peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999837"}
{"pmid": "20999838", "title": "The brain after intermittent exposure to simulated high altitude.", "content": "The brain after intermittent exposure to simulated high altitude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999838"}
{"pmid": "20999839", "title": "Acute myelitis; clinicopathologic study of a case.", "content": "Acute myelitis; clinicopathologic study of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999839"}
{"pmid": "20999840", "title": "Evaluation of results of electric shock treatment of the psychoneuroses.", "content": "Evaluation of results of electric shock treatment of the psychoneuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999840"}
{"pmid": "20999841", "title": "Reevaluation of contraindications to electric shock therapy.", "content": "Reevaluation of contraindications to electric shock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999841"}
{"pmid": "20999842", "title": "Histopathologic study of an early case of schizophrenia in which electric shock therapy had previously been employed.", "content": "Histopathologic study of an early case of schizophrenia in which electric shock therapy had previously been employed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999842"}
{"pmid": "20999843", "title": "Intravenous administration of histamine in treatment of migraine.", "content": "Intravenous administration of histamine in treatment of migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999843"}
{"pmid": "20999845", "title": "Primary behavior disorders and psychopathic personality; correlations of the electroencephalogram with family history and antecedent illness or injury.", "content": "Primary behavior disorders and psychopathic personality; correlations of the electroencephalogram with family history and antecedent illness or injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999845"}
{"pmid": "20999844", "title": "Electrical skin resistance test in evaluation of peripheral nerve injuries.", "content": "Electrical skin resistance test in evaluation of peripheral nerve injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999844"}
{"pmid": "20999846", "title": "Cleidocranial dysostosis with psychosis.", "content": "Cleidocranial dysostosis with psychosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999846"}
{"pmid": "20999847", "title": "Electrical paresthesias in the extremities following injury to the central nervous system.", "content": "Electrical paresthesias in the extremities following injury to the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999847"}
{"pmid": "20999848", "title": "Histologic study of the brain in experimentally induced acidosis.", "content": "Histologic study of the brain in experimentally induced acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999848"}
{"pmid": "20999849", "title": "Meningoencephalitis complicating herpes zoster ophthalmicus after treatment by vaccination.", "content": "Meningoencephalitis complicating herpes zoster ophthalmicus after treatment by vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999849"}
{"pmid": "20999850", "title": "Surgical treatment of syringobulbia and syringopontia.", "content": "Surgical treatment of syringobulbia and syringopontia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999850"}
{"pmid": "20999852", "title": "Group psychotherapy with private patients.", "content": "Group psychotherapy with private patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999852"}
{"pmid": "20999851", "title": "A warning concerning the use of curare in convulsive shock treatment of patients with psychiatric disorders who may have myasthenia gravis.", "content": "A warning concerning the use of curare in convulsive shock treatment of patients with psychiatric disorders who may have myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999851"}
{"pmid": "20999853", "title": "Suprasellar calcified lesion of unusual size.", "content": "Suprasellar calcified lesion of unusual size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999853"}
{"pmid": "20999854", "title": "Paroxysmal attacks of unilateral sweating associated with a pontile lesion.", "content": "Paroxysmal attacks of unilateral sweating associated with a pontile lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999854"}
{"pmid": "20999855", "title": "Oneirophrenia, a clinicophysiologic syndrome.", "content": "Oneirophrenia, a clinicophysiologic syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999855"}
{"pmid": "20999856", "title": "Electronic devices for use in modern neuropsychiatry.", "content": "Electronic devices for use in modern neuropsychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999856"}
{"pmid": "20999857", "title": "Winter General Hospital.", "content": "Winter General Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999857"}
{"pmid": "20999858", "title": "Some recent observations on the use of hypnosis in psychotherapy.", "content": "Some recent observations on the use of hypnosis in psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999858"}
{"pmid": "20999860", "title": "Re-education as a therapeutic and preventive technique.", "content": "Re-education as a therapeutic and preventive technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999860"}
{"pmid": "20999859", "title": "Techniques of hypnoanalysis illustrated in a case report.", "content": "Techniques of hypnoanalysis illustrated in a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999859"}
{"pmid": "20999861", "title": "The Veterans Clinic of Detroit.", "content": "The Veterans Clinic of Detroit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999861"}
{"pmid": "20999862", "title": "The sense of well being and its relation to clinical improvement.", "content": "The sense of well being and its relation to clinical improvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999862"}
{"pmid": "20999863", "title": "Psychotherapy of a phobia in a pilot.", "content": "Psychotherapy of a phobia in a pilot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999863"}
{"pmid": "20999865", "title": "Some problems in narcolepsy.", "content": "Some problems in narcolepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999865"}
{"pmid": "20999864", "title": "Amnesia with spontaneous recovery.", "content": "Amnesia with spontaneous recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999864"}
{"pmid": "20999866", "title": "Lear's nonsense.", "content": "Lear's nonsense.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999866"}
{"pmid": "20999867", "title": "Psychiatry and the social crisis.", "content": "Psychiatry and the social crisis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999867"}
{"pmid": "20999868", "title": "The management of the maladjusted soldier at the basic training center.", "content": "The management of the maladjusted soldier at the basic training center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999868"}
{"pmid": "20999869", "title": "The psychology of shock therapies and of leucotomy.", "content": "The psychology of shock therapies and of leucotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999869"}
{"pmid": "20999870", "title": "Ethnological attitudes toward death; a psychoanalytic evaluation.", "content": "Ethnological attitudes toward death; a psychoanalytic evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999870"}
{"pmid": "20999872", "title": "Marihuana; a factor in personality evaluation and Army maladjustment.", "content": "Marihuana; a factor in personality evaluation and Army maladjustment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999872"}
{"pmid": "20999871", "title": "Ceremonial prostitution in Duau (Normanby Island).", "content": "Ceremonial prostitution in Duau (Normanby Island).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999871"}
{"pmid": "20999873", "title": "Drama and the evocation of unconscious images.", "content": "Drama and the evocation of unconscious images.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999873"}
{"pmid": "20999874", "title": "A psychological view of the causes of criminal behavior.", "content": "A psychological view of the causes of criminal behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999874"}
{"pmid": "20999875", "title": "Employment of neurotics.", "content": "Employment of neurotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999875"}
{"pmid": "20999876", "title": "A case of of fatal air embolism through an unusual sexual act (medical and legal implications).", "content": "A case of of fatal air embolism through an unusual sexual act (medical and legal implications).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999876"}
{"pmid": "20999877", "title": "The post-analytic migratory symptom.", "content": "The post-analytic migratory symptom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999877"}
{"pmid": "20999878", "title": "A peculiar intermediary state between waking and sleep.", "content": "A peculiar intermediary state between waking and sleep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999878"}
{"pmid": "20999879", "title": "Heart disease in children.", "content": "Heart disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999879"}
{"pmid": "20999880", "title": "Nursing care of children with heart disease.", "content": "Nursing care of children with heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999880"}
{"pmid": "20999881", "title": "The public health nurse and the cardiac child.", "content": "The public health nurse and the cardiac child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999881"}
{"pmid": "20999882", "title": "The nursing profession and the evolution of public social services.", "content": "The nursing profession and the evolution of public social services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999882"}
{"pmid": "20999883", "title": "The treatment of infantile paralysis based on the Kenny conception.", "content": "The treatment of infantile paralysis based on the Kenny conception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999883"}
{"pmid": "20999884", "title": "Preparing the nurse for present day responsibilities.", "content": "Preparing the nurse for present day responsibilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999884"}
{"pmid": "20999885", "title": "The 1946 census of public health nurses.", "content": "The 1946 census of public health nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999885"}
{"pmid": "20999886", "title": "Rehabilitation on the job.", "content": "Rehabilitation on the job.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999886"}
{"pmid": "20999887", "title": "Early diagnosis and treatment of cancer.", "content": "Early diagnosis and treatment of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999887"}
{"pmid": "20999888", "title": "School nurse, school physician, and teacher health.", "content": "School nurse, school physician, and teacher health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999888"}
{"pmid": "20999889", "title": "Keeping your patient cool.", "content": "Keeping your patient cool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999889"}
{"pmid": "20999890", "title": "Why nutrition belongs in nursing.", "content": "Why nutrition belongs in nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999890"}
{"pmid": "20999891", "title": "Nursing the polio patient at home.", "content": "Nursing the polio patient at home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999891"}
{"pmid": "20999892", "title": "The yellow flag flies again.", "content": "The yellow flag flies again.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999892"}
{"pmid": "20999893", "title": "GLASS plastic; aid to orthopedic surgery.", "content": "GLASS plastic; aid to orthopedic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999893"}
{"pmid": "20999894", "title": "A brief summary of corneal transplantation.", "content": "A brief summary of corneal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999894"}
{"pmid": "20999895", "title": "Some legal aspects of professional nursing.", "content": "Some legal aspects of professional nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999895"}
{"pmid": "20999896", "title": "YALE Clinic of Child Development investigates vision in infancy and childhood.", "content": "YALE Clinic of Child Development investigates vision in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999896"}
{"pmid": "20999897", "title": "NEW A-O plastic implant closely matches movement of normal eye.", "content": "NEW A-O plastic implant closely matches movement of normal eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999897"}
{"pmid": "20999898", "title": "Perimetry and accessory tests.", "content": "Perimetry and accessory tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999898"}
{"pmid": "20999899", "title": "Bifocals in anisometropia.", "content": "Bifocals in anisometropia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999899"}
{"pmid": "20999900", "title": "Arguments of the antispectacle cults.", "content": "Arguments of the antispectacle cults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999900"}
{"pmid": "20999901", "title": "Ocular functions in subclinical intoxication.", "content": "Ocular functions in subclinical intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999901"}
{"pmid": "20999906", "title": "Foreign bodies in the eye.", "content": "Foreign bodies in the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999906"}
{"pmid": "20999907", "title": "Some aspects of a local prevention of blindness program.", "content": "Some aspects of a local prevention of blindness program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999907"}
{"pmid": "20999908", "title": "Do you make the most of your eyes?", "content": "Do you make the most of your eyes?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999908"}
{"pmid": "20999909", "title": "Dealing with visual problems in the classroom.", "content": "Dealing with visual problems in the classroom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999909"}
{"pmid": "20999902", "title": "Space perception in its normal and abnormal aspects.", "content": "Space perception in its normal and abnormal aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999902"}
{"pmid": "20999910", "title": "Clinical notes on progressive congenital deafness.", "content": "Clinical notes on progressive congenital deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999910"}
{"pmid": "20999911", "title": "Temporary deafness due to gunfire.", "content": "Temporary deafness due to gunfire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999911"}
{"pmid": "20999912", "title": "Herpes zoster oticus.", "content": "Herpes zoster oticus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999912"}
{"pmid": "20999904", "title": "Screening visual defects in school children.", "content": "Screening visual defects in school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999904"}
{"pmid": "20999903", "title": "Mirror technique of vision training.", "content": "Mirror technique of vision training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999903"}
{"pmid": "20999913", "title": "Radiate formation on pathogenic fungi in human tissue.", "content": "Radiate formation on pathogenic fungi in human tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999913"}
{"pmid": "20999914", "title": "The leukopenic factor of exudates; the mechanism concerned in the leukopenia induced by it.", "content": "The leukopenic factor of exudates; the mechanism concerned in the leukopenia induced by it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999914"}
{"pmid": "20999915", "title": "Experimental endocarditis of dogs.", "content": "Experimental endocarditis of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999915"}
{"pmid": "20999916", "title": "In vitro studies on the physiology of cells; interactions of thymic cells and an oxidation-reduction indicator, 2,6-dichlorophenolindophenol.", "content": "In vitro studies on the physiology of cells; interactions of thymic cells and an oxidation-reduction indicator, 2,6-dichlorophenolindophenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999916"}
{"pmid": "20999918", "title": "Experimental medionecrosis of the aorta.", "content": "Experimental medionecrosis of the aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999918"}
{"pmid": "20999917", "title": "Cerebral concussion; histochemical demonstration of nucleases in the cerebrospinal fluid.", "content": "Cerebral concussion; histochemical demonstration of nucleases in the cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999917"}
{"pmid": "20999919", "title": "Course of wound healing in the skin of mice under the influence of carcinogens.", "content": "Course of wound healing in the skin of mice under the influence of carcinogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999919"}
{"pmid": "20999920", "title": "Disseminated reticuloendothelial tumor of the bone marrow with nodular osteosclerosis.", "content": "Disseminated reticuloendothelial tumor of the bone marrow with nodular osteosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999920"}
{"pmid": "20999921", "title": "Alloxantin; an investigation of the substance as used in experimental production of diabetes.", "content": "Alloxantin; an investigation of the substance as used in experimental production of diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999921"}
{"pmid": "20999922", "title": "Reaction of rats following injection of anti-rat-heart immune serum.", "content": "Reaction of rats following injection of anti-rat-heart immune serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999922"}
{"pmid": "20999923", "title": "Duodenitis with diverticulum and ectopic pancreatic tissue.", "content": "Duodenitis with diverticulum and ectopic pancreatic tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999923"}
{"pmid": "20999924", "title": "Complete absence of the left lobe of the liver.", "content": "Complete absence of the left lobe of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999924"}
{"pmid": "20999925", "title": "Epidemic poliomyelitis; some pathologic observations on human material.", "content": "Epidemic poliomyelitis; some pathologic observations on human material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999925"}
{"pmid": "20999926", "title": "Primary hyperparathyroidism; a report of five cases that exemplify special features of this disease (infarction of a parathyroid adenoma; oxyphil adenoma).", "content": "Primary hyperparathyroidism; a report of five cases that exemplify special features of this disease (infarction of a parathyroid adenoma; oxyphil adenoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999926"}
{"pmid": "20999927", "title": "Functioning of the fetal kidney as reflected by stillborn infants with hydroureter and hydronephrosis.", "content": "Functioning of the fetal kidney as reflected by stillborn infants with hydroureter and hydronephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999927"}
{"pmid": "20999928", "title": "Experimental cholesterol arteriosclerosis; changes produced in skeletal muscle.", "content": "Experimental cholesterol arteriosclerosis; changes produced in skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999928"}
{"pmid": "20999929", "title": "Atherosclerotic valvular disease of the heart.", "content": "Atherosclerotic valvular disease of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999929"}
{"pmid": "20999930", "title": "Reaction of the reticulo endothelial cells to subcutaneous injections of cholesterol; experimental animals; mice.", "content": "Reaction of the reticulo endothelial cells to subcutaneous injections of cholesterol; experimental animals; mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999930"}
{"pmid": "20999931", "title": "Systemic multicentric lipoblastosis.", "content": "Systemic multicentric lipoblastosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999931"}
{"pmid": "20999932", "title": "Primary Hodgkin's sarcoma of the brain.", "content": "Primary Hodgkin's sarcoma of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999932"}
{"pmid": "20999933", "title": "Primary melanoma of the adrenal gland.", "content": "Primary melanoma of the adrenal gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999933"}
{"pmid": "20999934", "title": "A centrifuge method of determining blood proteins.", "content": "A centrifuge method of determining blood proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999934"}
{"pmid": "20999935", "title": "Hyperpnoea induced by forced breathing.", "content": "Hyperpnoea induced by forced breathing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999935"}
{"pmid": "20999936", "title": "The site of pressor action of the base A, closely allied to l-nicotine, present in urine.", "content": "The site of pressor action of the base A, closely allied to l-nicotine, present in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999936"}
{"pmid": "20999937", "title": "The appearance of a base, detected by a colour test, in the urine of bitches having renal ischaemia.", "content": "The appearance of a base, detected by a colour test, in the urine of bitches having renal ischaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999937"}
{"pmid": "20999938", "title": "The properties and pharmacological action of a base liberated by alkaline hydrolysis of normal urine, compared with those of a similar base found free in the urine of dogs with renal ischaemia.", "content": "The properties and pharmacological action of a base liberated by alkaline hydrolysis of normal urine, compared with those of a similar base found free in the urine of dogs with renal ischaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999938"}
{"pmid": "20999939", "title": "Conduction velocity and myelin thickness in regenerating nerve fibres.", "content": "Conduction velocity and myelin thickness in regenerating nerve fibres.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999939"}
{"pmid": "20999940", "title": "The production and removal of oedema fluid in the lung after exposure to carbonyl chloride (phosgene).", "content": "The production and removal of oedema fluid in the lung after exposure to carbonyl chloride (phosgene).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999940"}
{"pmid": "20999941", "title": "The absorption of fluids from the lungs.", "content": "The absorption of fluids from the lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999941"}
{"pmid": "20999942", "title": "The nucleoproteins of the liver cell demonstrated by ultra-violet microscopy.", "content": "The nucleoproteins of the liver cell demonstrated by ultra-violet microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999942"}
{"pmid": "20999943", "title": "The oxygen consumption of the sheep foetus.", "content": "The oxygen consumption of the sheep foetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999943"}
{"pmid": "20999944", "title": "A histamine dilatation abolished by atropine.", "content": "A histamine dilatation abolished by atropine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999944"}
{"pmid": "20999945", "title": "Radiomicrography; a preliminary communication.", "content": "Radiomicrography; a preliminary communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999945"}
{"pmid": "20999946", "title": "The World Health Organization.", "content": "The World Health Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999946"}
{"pmid": "20999947", "title": "School health in Ecuador.", "content": "School health in Ecuador.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999947"}
{"pmid": "20999948", "title": "Mapping the field of contamination over an ocean sewer outfall.", "content": "Mapping the field of contamination over an ocean sewer outfall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999948"}
{"pmid": "20999949", "title": "Dose measurement in beta-ray therapy.", "content": "Dose measurement in beta-ray therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999949"}
{"pmid": "20999950", "title": "Dose measurements with radium beta-ray applicators.", "content": "Dose measurements with radium beta-ray applicators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999950"}
{"pmid": "20999951", "title": "New units for the measurement of radioactivity.", "content": "New units for the measurement of radioactivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999951"}
{"pmid": "20999952", "title": "Pyridoxine in treatment of radiation sickness.", "content": "Pyridoxine in treatment of radiation sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999952"}
{"pmid": "20999953", "title": "Moscow's x-ray services.", "content": "Moscow's x-ray services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999953"}
{"pmid": "20999954", "title": "Radiological demonstration of regression of retro-peritoneal Hodgkin's disease.", "content": "Radiological demonstration of regression of retro-peritoneal Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999954"}
{"pmid": "20999955", "title": "Subacute ileo-ileal intussusception in the adult.", "content": "Subacute ileo-ileal intussusception in the adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999955"}
{"pmid": "20999956", "title": "Wrist injuries in service patients.", "content": "Wrist injuries in service patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999956"}
{"pmid": "20999957", "title": "The x-ray appearances of pharyngeal palsy.", "content": "The x-ray appearances of pharyngeal palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999957"}
{"pmid": "20999958", "title": "Leontiasis ossea.", "content": "Leontiasis ossea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999958"}
{"pmid": "20999959", "title": "The response of Tradescantia pollen grains to radiation at different dosage-rates.", "content": "The response of Tradescantia pollen grains to radiation at different dosage-rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999959"}
{"pmid": "20999960", "title": "X-ray therapy with a continuously rotating beam; apparatus and associated physical problems.", "content": "X-ray therapy with a continuously rotating beam; apparatus and associated physical problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999960"}
{"pmid": "20999962", "title": "A case of intersigmoid hernia with illustrations of x-ray appearances.", "content": "A case of intersigmoid hernia with illustrations of x-ray appearances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999962"}
{"pmid": "20999961", "title": "Radiological diagnosis of lumbar intervertebral disc lesions.", "content": "Radiological diagnosis of lumbar intervertebral disc lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999961"}
{"pmid": "20999963", "title": "Radiological investigation of a case of pedal hyperphalangism and supernumerary phalangeal epiphysis.", "content": "Radiological investigation of a case of pedal hyperphalangism and supernumerary phalangeal epiphysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999963"}
{"pmid": "20999964", "title": "A survey of radiographical techniques employed in obstetrical and gynaecological practice.", "content": "A survey of radiographical techniques employed in obstetrical and gynaecological practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999964"}
{"pmid": "20999965", "title": "Approach to radiotherapy.", "content": "Approach to radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999965"}
{"pmid": "20999966", "title": "Improving an x-ray room for children.", "content": "Improving an x-ray room for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999966"}
{"pmid": "20999968", "title": "A simple and accurate technique for finding the position of the anode.", "content": "A simple and accurate technique for finding the position of the anode.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999968"}
{"pmid": "20999967", "title": "The radiographer and his equipment.", "content": "The radiographer and his equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999967"}
{"pmid": "20999969", "title": "A technique for teleradiography of a lateral cervical spine.", "content": "A technique for teleradiography of a lateral cervical spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999969"}
{"pmid": "20999970", "title": "Treatment of fractures.", "content": "Treatment of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999970"}
{"pmid": "20999971", "title": "Pharyngo-esophageal diverticulum; its management and complications.", "content": "Pharyngo-esophageal diverticulum; its management and complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999971"}
{"pmid": "20999972", "title": "Diverticula of the lower thoracic esophagus; report of six, four of which were operated upon.", "content": "Diverticula of the lower thoracic esophagus; report of six, four of which were operated upon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999972"}
{"pmid": "20999973", "title": "Carcinoma of the midthoracic esophagus; its treatment by radical resection and high intrathoracic esophagogastric anastomosis.", "content": "Carcinoma of the midthoracic esophagus; its treatment by radical resection and high intrathoracic esophagogastric anastomosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999973"}
{"pmid": "20999974", "title": "Bronchiogenic carcinoma.", "content": "Bronchiogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999974"}
{"pmid": "20999975", "title": "Palliative gastrectomy in selected cases of gastric ulcer.", "content": "Palliative gastrectomy in selected cases of gastric ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999975"}
{"pmid": "20999976", "title": "Subtotal gastrectomy for duodenal ulcer.", "content": "Subtotal gastrectomy for duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999976"}
{"pmid": "20999977", "title": "Congenital hypertrophic pyloric stenosis.", "content": "Congenital hypertrophic pyloric stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999977"}
{"pmid": "20999978", "title": "Late results in the treatment of ulcerative colitis.", "content": "Late results in the treatment of ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999978"}
{"pmid": "20999979", "title": "Diverticulitis of the colon.", "content": "Diverticulitis of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999979"}
{"pmid": "20999980", "title": "Resection of abdominal carcinomas involving the liver and spleen secondarily.", "content": "Resection of abdominal carcinomas involving the liver and spleen secondarily.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999980"}
{"pmid": "20999981", "title": "Definitive surgery of the large intestine following war wounds.", "content": "Definitive surgery of the large intestine following war wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999981"}
{"pmid": "20999982", "title": "Early ambulation in abdominal surgery.", "content": "Early ambulation in abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999982"}
{"pmid": "20999983", "title": "Tests for collateral circulation in the extremities.", "content": "Tests for collateral circulation in the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999983"}
{"pmid": "20999984", "title": "Effect of penicillin in experimental intestinal obstruction; cure of strangulated ileal obstructions treated with penicillin prior to late resection.", "content": "Effect of penicillin in experimental intestinal obstruction; cure of strangulated ileal obstructions treated with penicillin prior to late resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999984"}
{"pmid": "20999985", "title": "Air force battle casualties; an experience with acute injuries of eight hundred and thirty-nine battle casualties from the Eight Air Force.", "content": "Air force battle casualties; an experience with acute injuries of eight hundred and thirty-nine battle casualties from the Eight Air Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999985"}
{"pmid": "20999986", "title": "Orbicularis oris muscle in double harelip.", "content": "Orbicularis oris muscle in double harelip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999986"}
{"pmid": "20999987", "title": "Fatalities following war wounds of the abdomen.", "content": "Fatalities following war wounds of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999987"}
{"pmid": "20999988", "title": "Production of experimental portal hypertension in the dog; anatomy of the hepatic veins in the dog.", "content": "Production of experimental portal hypertension in the dog; anatomy of the hepatic veins in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999988"}
{"pmid": "20999989", "title": "Carcinoma of pancreas still local at autopsy four years after palliative operation.", "content": "Carcinoma of pancreas still local at autopsy four years after palliative operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999989"}
{"pmid": "20999990", "title": "Para-articular ossification of the soft parts of the ankle; complication of sprain with or without fracture of the shaft of the ipsilateral fibula.", "content": "Para-articular ossification of the soft parts of the ankle; complication of sprain with or without fracture of the shaft of the ipsilateral fibula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999990"}
{"pmid": "20999991", "title": "Injuries of the thoracic duct; report of a case of chylothorax in which the patient recovered after ligation of the thoracic duct.", "content": "Injuries of the thoracic duct; report of a case of chylothorax in which the patient recovered after ligation of the thoracic duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999991"}
{"pmid": "20999992", "title": "Arteriosclerosis obliterans of the abdominal aorta.", "content": "Arteriosclerosis obliterans of the abdominal aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999992"}
{"pmid": "20999993", "title": "Acute fulminating ulcerative colitis with massive perforation and peritonitis.", "content": "Acute fulminating ulcerative colitis with massive perforation and peritonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999993"}
{"pmid": "20999994", "title": "Primary peritonitis caused by Friedländer's bacillus report of a case with recovery following sulfadia zine therapy.", "content": "Primary peritonitis caused by Friedländer's bacillus report of a case with recovery following sulfadia zine therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999994"}
{"pmid": "20999995", "title": "Blood level of phenol in uremia.", "content": "Blood level of phenol in uremia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20999995"}
{"pmid": "21000002", "title": "The surgical treatment of cancer of the rectum and pelvic colon without colostomy and with preservation of sphincter muscles.", "content": "The surgical treatment of cancer of the rectum and pelvic colon without colostomy and with preservation of sphincter muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000002"}
{"pmid": "21000003", "title": "Transplantation of the ureters to the bowel.", "content": "Transplantation of the ureters to the bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000003"}
{"pmid": "21000016", "title": "The direct approach to cardiovascular diseases.", "content": "The direct approach to cardiovascular diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000016"}
{"pmid": "21000004", "title": "Experiments with cuto-omentopexy and skin homotransplantation.", "content": "Experiments with cuto-omentopexy and skin homotransplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000004"}
{"pmid": "21000007", "title": "Intra-abdominal plastic repair.", "content": "Intra-abdominal plastic repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000007"}
{"pmid": "21000005", "title": "A simple, thorough operative technic for excochleation of disc herniation.", "content": "A simple, thorough operative technic for excochleation of disc herniation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000005"}
{"pmid": "21000017", "title": "Surgically removed foreign body embolus in the pulmonary artery.", "content": "Surgically removed foreign body embolus in the pulmonary artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000017"}
{"pmid": "21000018", "title": "Peptic ulcer of the esophagus.", "content": "Peptic ulcer of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000018"}
{"pmid": "21000008", "title": "Phlebitis, embolism and thrombosis.", "content": "Phlebitis, embolism and thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000008"}
{"pmid": "21000019", "title": "Intrathoracic gastric cyst.", "content": "Intrathoracic gastric cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000019"}
{"pmid": "21000020", "title": "Crushing injuries of the chest.", "content": "Crushing injuries of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000020"}
{"pmid": "21000006", "title": "Carcinoma of the breast.", "content": "Carcinoma of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000006"}
{"pmid": "21000021", "title": "Acute suppurative mediastinitis.", "content": "Acute suppurative mediastinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000021"}
{"pmid": "21000010", "title": "Surgical plagiarism; its etiology, manifestations, prophylaxis and cure.", "content": "Surgical plagiarism; its etiology, manifestations, prophylaxis and cure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000010"}
{"pmid": "21000009", "title": "Some items on the treatment of urethral strictures; a simplified operative method for impassable strictures.", "content": "Some items on the treatment of urethral strictures; a simplified operative method for impassable strictures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000009"}
{"pmid": "21000022", "title": "Open pneumonolysis; an adjunct to pneumothorax and closed pneumonolysis.", "content": "Open pneumonolysis; an adjunct to pneumothorax and closed pneumonolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000022"}
{"pmid": "21000023", "title": "The initial surgery of thoracoabdominal war injuries.", "content": "The initial surgery of thoracoabdominal war injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000023"}
{"pmid": "21000024", "title": "Arterial injuries of the thorax.", "content": "Arterial injuries of the thorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000024"}
{"pmid": "21000025", "title": "Benign tumor formations of the large bowel.", "content": "Benign tumor formations of the large bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000025"}
{"pmid": "21000026", "title": "Scalp lesions causing headache; surgical treatment.", "content": "Scalp lesions causing headache; surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000026"}
{"pmid": "21000027", "title": "The treatment of penetrating wounds of the brain produced by missiles of warfare.", "content": "The treatment of penetrating wounds of the brain produced by missiles of warfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000027"}
{"pmid": "21000012", "title": "The treatment of chronic osteomyelitis.", "content": "The treatment of chronic osteomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000012"}
{"pmid": "21000028", "title": "The small community hospital.", "content": "The small community hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000028"}
{"pmid": "21000013", "title": "Management of cholecystitis.", "content": "Management of cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000013"}
{"pmid": "21000014", "title": "Surgical treatment of varicose veins.", "content": "Surgical treatment of varicose veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000014"}
{"pmid": "21000011", "title": "A late effect of radiotherapy upon the intestine.", "content": "A late effect of radiotherapy upon the intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000011"}
{"pmid": "21000029", "title": "Graft substitution of long bone shaft defects.", "content": "Graft substitution of long bone shaft defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000029"}
{"pmid": "21000030", "title": "Continuous spinal analgesia and anesthesia in surgery, obstetrics and therapeutics.", "content": "Continuous spinal analgesia and anesthesia in surgery, obstetrics and therapeutics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000030"}
{"pmid": "21000031", "title": "Radicular pain due to ruptured cervical disk.", "content": "Radicular pain due to ruptured cervical disk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000031"}
{"pmid": "21000032", "title": "The surgical treatment of acute cholecystitis.", "content": "The surgical treatment of acute cholecystitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000032"}
{"pmid": "21000033", "title": "Meckel's diverticulum.", "content": "Meckel's diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000033"}
{"pmid": "21000034", "title": "Personal experiences in the surgical treatment of gastric and duodenal ulcer.", "content": "Personal experiences in the surgical treatment of gastric and duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000034"}
{"pmid": "21000035", "title": "Partial hepatectomy in certain primary tumors of the liver.", "content": "Partial hepatectomy in certain primary tumors of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000035"}
{"pmid": "21000036", "title": "The management of the ruptured appendix.", "content": "The management of the ruptured appendix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000036"}
{"pmid": "21000037", "title": "Physical medicine facing forward.", "content": "Physical medicine facing forward.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000037"}
{"pmid": "21000038", "title": "Effect of elevated body temperature on the plasma ascorbic acid.", "content": "Effect of elevated body temperature on the plasma ascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000038"}
{"pmid": "21000039", "title": "Heavy resistance exercises.", "content": "Heavy resistance exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000039"}
{"pmid": "21000040", "title": "Address [on reconditioning].", "content": "Address [on reconditioning].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000040"}
{"pmid": "21000041", "title": "Address [on reconditioning].", "content": "Address [on reconditioning].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000041"}
{"pmid": "21000042", "title": "Address [on reconditioning].", "content": "Address [on reconditioning].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000042"}
{"pmid": "21000044", "title": "Aspiration type of congenital tuberculosis.", "content": "Aspiration type of congenital tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000044"}
{"pmid": "21000045", "title": "Morbidity of tuberculosis; statistical aspects.", "content": "Morbidity of tuberculosis; statistical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000045"}
{"pmid": "21000047", "title": "The use of a fibrinogen coagulum in pyelolithotomy.", "content": "The use of a fibrinogen coagulum in pyelolithotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000047"}
{"pmid": "21000046", "title": "Dicoumarol prophylaxis in thoracic surgery.", "content": "Dicoumarol prophylaxis in thoracic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000046"}
{"pmid": "21000049", "title": "Hydronephrosis in soldiers due to obstruction at the uretero-pelvic junction.", "content": "Hydronephrosis in soldiers due to obstruction at the uretero-pelvic junction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000049"}
{"pmid": "21000048", "title": "Intravenous urography in acute renal colic.", "content": "Intravenous urography in acute renal colic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000048"}
{"pmid": "21000051", "title": "A unique case of submucosal epithelial nests in the ureter and renal pelvis.", "content": "A unique case of submucosal epithelial nests in the ureter and renal pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000051"}
{"pmid": "21000050", "title": "The association of hypernephroma with amyloidosis of the kidney.", "content": "The association of hypernephroma with amyloidosis of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000050"}
{"pmid": "21000052", "title": "Instrumental perforation of the ureter.", "content": "Instrumental perforation of the ureter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000052"}
{"pmid": "21000053", "title": "Ectopic ureter draining into the seminal vesicle.", "content": "Ectopic ureter draining into the seminal vesicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000053"}
{"pmid": "21000054", "title": "The bladder biopsy; an evaluation of the cystoscopic procedure.", "content": "The bladder biopsy; an evaluation of the cystoscopic procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000054"}
{"pmid": "21000055", "title": "A new bladder evacuator.", "content": "A new bladder evacuator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000055"}
{"pmid": "21000057", "title": "Neoplasms of the testis.", "content": "Neoplasms of the testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000057"}
{"pmid": "21000056", "title": "Diverticula of the prostate.", "content": "Diverticula of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000056"}
{"pmid": "21000058", "title": "Oxidized cellulose (absorbable hemostatic gauze; cellulosic acid); its use in genito-urinary surgery.", "content": "Oxidized cellulose (absorbable hemostatic gauze; cellulosic acid); its use in genito-urinary surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000058"}
{"pmid": "21000059", "title": "Cyst of the accessory genital tract; a case report with a review of the literature.", "content": "Cyst of the accessory genital tract; a case report with a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000059"}
{"pmid": "21000060", "title": "Urinary extravasation; a study of sixty cases.", "content": "Urinary extravasation; a study of sixty cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000060"}
{"pmid": "21000061", "title": "Ditopax; a new excretory urographic medium; a clinical report on 1280 injections.", "content": "Ditopax; a new excretory urographic medium; a clinical report on 1280 injections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000061"}
{"pmid": "21000062", "title": "Pathogenesis of the cardiovascular and renal changes which usually accompany malignant hypertension.", "content": "Pathogenesis of the cardiovascular and renal changes which usually accompany malignant hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000062"}
{"pmid": "21000063", "title": "Thrush of the urinary bladder.", "content": "Thrush of the urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000063"}
{"pmid": "21000064", "title": "Cancer in diverticulum of the bladder; a pitfall to the resectionist.", "content": "Cancer in diverticulum of the bladder; a pitfall to the resectionist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000064"}
{"pmid": "21000065", "title": "Sulfathiazole suppositories in treatment of vulvovaginitis in children.", "content": "Sulfathiazole suppositories in treatment of vulvovaginitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000065"}
{"pmid": "21000066", "title": "Multiple fibromata of tunica vaginalis testis or a proliferative type of chronic periorchitis; a report of two cases.", "content": "Multiple fibromata of tunica vaginalis testis or a proliferative type of chronic periorchitis; a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000066"}
{"pmid": "21000067", "title": "Multiple, benign, fibrous tumors of tunica vaginalis testis.", "content": "Multiple, benign, fibrous tumors of tunica vaginalis testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000067"}
{"pmid": "21000068", "title": "Adenomatoid tumors of the epididymis.", "content": "Adenomatoid tumors of the epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000068"}
{"pmid": "21000069", "title": "Cholesteatoma of the epididymis.", "content": "Cholesteatoma of the epididymis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000069"}
{"pmid": "21000070", "title": "Carcinoma of the penis.", "content": "Carcinoma of the penis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000070"}
{"pmid": "21000071", "title": "Repair of war wounds of the bulbous and membranous urethra using split thickness skin grafts and penicillin.", "content": "Repair of war wounds of the bulbous and membranous urethra using split thickness skin grafts and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000071"}
{"pmid": "21000072", "title": "Injuries to the genito-urinary tract in the European Theater of Operation.", "content": "Injuries to the genito-urinary tract in the European Theater of Operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000072"}
{"pmid": "21000073", "title": "A report on the status of urology in Europe.", "content": "A report on the status of urology in Europe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000073"}
{"pmid": "21000074", "title": "A debris scraping cystoscopic fulgurating device.", "content": "A debris scraping cystoscopic fulgurating device.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000074"}
{"pmid": "21000075", "title": "Coincident pararenal tuberculoma and tumor of the renal pelvis.", "content": "Coincident pararenal tuberculoma and tumor of the renal pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000075"}
{"pmid": "21000076", "title": "Fibroma of the tunica albuginea.", "content": "Fibroma of the tunica albuginea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000076"}
{"pmid": "21000077", "title": "Chromidrosis.", "content": "Chromidrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000077"}
{"pmid": "21000079", "title": "Pachyonychia congenita.", "content": "Pachyonychia congenita.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000079"}
{"pmid": "21000078", "title": "Ambulatory intensive treatment of syphilis with calcium penicillin in oil and wax.", "content": "Ambulatory intensive treatment of syphilis with calcium penicillin in oil and wax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000078"}
{"pmid": "21000080", "title": "Pompholyx; its etiology, pathogenesis and vaccine therapy, with particular reference to its military importance and post-war significance.", "content": "Pompholyx; its etiology, pathogenesis and vaccine therapy, with particular reference to its military importance and post-war significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000080"}
{"pmid": "21000082", "title": "PROSTITUTION in early Greece.", "content": "PROSTITUTION in early Greece.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000082"}
{"pmid": "21000081", "title": "Syphilis.", "content": "Syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000081"}
{"pmid": "21000083", "title": "The causes of the French pox.", "content": "The causes of the French pox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000083"}
{"pmid": "21000084", "title": "Penicillin in the treatment of neurosyphilis.", "content": "Penicillin in the treatment of neurosyphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000084"}
{"pmid": "21000085", "title": "The systematic treatment of 227 cases of arsenic poisoning (encephalitis, dermatitis, blood dyscrasias, jaundice, fever) with 2,3-demercaptopropanol (BAL).", "content": "The systematic treatment of 227 cases of arsenic poisoning (encephalitis, dermatitis, blood dyscrasias, jaundice, fever) with 2,3-demercaptopropanol (BAL).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000085"}
{"pmid": "21000086", "title": "Studies on the biologic relationship between the causative agents of syphilis, yaws and venereal spirochetosis of rabbits.", "content": "Studies on the biologic relationship between the causative agents of syphilis, yaws and venereal spirochetosis of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000086"}
{"pmid": "21000087", "title": "Studies on the biologic relationship between the causative agents of syphilis, yaws, and venereal spirochetosis of rabbits; comparison of the experimental disease produced in rabbits.", "content": "Studies on the biologic relationship between the causative agents of syphilis, yaws, and venereal spirochetosis of rabbits; comparison of the experimental disease produced in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000087"}
{"pmid": "21000088", "title": "Syphilitic nephrosis as a manifestation of a renal Herxheimer reaction following penicillin therapy for early syphilis.", "content": "Syphilitic nephrosis as a manifestation of a renal Herxheimer reaction following penicillin therapy for early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000088"}
{"pmid": "21000089", "title": "The therapeutic effectiveness of relatively crude commercial penicillin in early and late rabbit syphilis.", "content": "The therapeutic effectiveness of relatively crude commercial penicillin in early and late rabbit syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000089"}
{"pmid": "21000090", "title": "The rapid treatment of early syphilis with the combined use of penicillin and mapharsen.", "content": "The rapid treatment of early syphilis with the combined use of penicillin and mapharsen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000090"}
{"pmid": "21000091", "title": "Penicillin by mouth in the treatment of late cutaneous syphilis.", "content": "Penicillin by mouth in the treatment of late cutaneous syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000091"}
{"pmid": "21000092", "title": "Oral penicillin treatment of gonorrhea.", "content": "Oral penicillin treatment of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000092"}
{"pmid": "21000094", "title": "Surgical treatment of inguinal lymphogranuloma venereum; an analysis of 613 consecutive cases in the male.", "content": "Surgical treatment of inguinal lymphogranuloma venereum; an analysis of 613 consecutive cases in the male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000094"}
{"pmid": "21000093", "title": "The value of the quantitatively standardized complement fixation test in the diagnosis and treatment of early syphilis.", "content": "The value of the quantitatively standardized complement fixation test in the diagnosis and treatment of early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000093"}
{"pmid": "21000095", "title": "BRONCHIAL asthma.", "content": "BRONCHIAL asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000095"}
{"pmid": "21000096", "title": "RELATION of allergy to chronic diseases of the nose and paranasal sinuses.", "content": "RELATION of allergy to chronic diseases of the nose and paranasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000096"}
{"pmid": "21000098", "title": "ALLERGIC contact dermatitis.", "content": "ALLERGIC contact dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000098"}
{"pmid": "21000099", "title": "FOOD allergy.", "content": "FOOD allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000099"}
{"pmid": "21000097", "title": "ALLERGY to fungi.", "content": "ALLERGY to fungi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000097"}
{"pmid": "21000111", "title": "Introduction to the conference on experimental hypertension.", "content": "Introduction to the conference on experimental hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000111"}
{"pmid": "21000112", "title": "Introductory lecture on the production and pathogenesis of experimental hypertension.", "content": "Introductory lecture on the production and pathogenesis of experimental hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000112"}
{"pmid": "21000100", "title": "Substance or system; the riddle of morphogenesis.", "content": "Substance or system; the riddle of morphogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000100"}
{"pmid": "21000101", "title": "On the mechanism of heterosis; the chromosomal or cytoplasmic basis for heterosis in Drosophila melanogaster.", "content": "On the mechanism of heterosis; the chromosomal or cytoplasmic basis for heterosis in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000101"}
{"pmid": "21000113", "title": "Mechanism of renal hypertension.", "content": "Mechanism of renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000113"}
{"pmid": "21000102", "title": "Production of female offspring by virgin females in the greenhouse whitefly, Trialeurodes vaporariorum, under the influence of high temperatures.", "content": "Production of female offspring by virgin females in the greenhouse whitefly, Trialeurodes vaporariorum, under the influence of high temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000102"}
{"pmid": "21000103", "title": "Stability of the sex alleles of Habrobracon.", "content": "Stability of the sex alleles of Habrobracon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000103"}
{"pmid": "21000116", "title": "Experimental chronic hypertension; its mechanism and amelioration by use of various blood-pressure-reducing substances.", "content": "Experimental chronic hypertension; its mechanism and amelioration by use of various blood-pressure-reducing substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000116"}
{"pmid": "21000114", "title": "The metabolism of the kidneys in experimental renal hypertension.", "content": "The metabolism of the kidneys in experimental renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000114"}
{"pmid": "21000115", "title": "Renin and renal hypertension.", "content": "Renin and renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000115"}
{"pmid": "21000105", "title": "A system of scoring linkage data, with special reference to the pied factors in mice.", "content": "A system of scoring linkage data, with special reference to the pied factors in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000105"}
{"pmid": "21000117", "title": "Treatment and prophylaxis of experimental renal hypertension with renal extracts and marine oils.", "content": "Treatment and prophylaxis of experimental renal hypertension with renal extracts and marine oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000117"}
{"pmid": "21000118", "title": "Some physiological aspects of the blood-pressure-lowering effect of tissue extracts in the hypertensive animal.", "content": "Some physiological aspects of the blood-pressure-lowering effect of tissue extracts in the hypertensive animal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000118"}
{"pmid": "21000119", "title": "A change of mechanism in the course of hypertension of renal origin.", "content": "A change of mechanism in the course of hypertension of renal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000119"}
{"pmid": "21000120", "title": "Experimental renal hypertension and amino acid metabolism in the kidney.", "content": "Experimental renal hypertension and amino acid metabolism in the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000120"}
{"pmid": "21000104", "title": "The viroid theory in relation to plasmagenes, viruses, cancer and plastids.", "content": "The viroid theory in relation to plasmagenes, viruses, cancer and plastids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000104"}
{"pmid": "21000106", "title": "The relationship of x-ray induced recessive lethals to chromosomal breakage.", "content": "The relationship of x-ray induced recessive lethals to chromosomal breakage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000106"}
{"pmid": "21000121", "title": "The effect of varying the conditions of hydrolyzing casein with sulfuric acid upon the optical rotation and the amino and ammonia nitrogen content of the hydrolyzates.", "content": "The effect of varying the conditions of hydrolyzing casein with sulfuric acid upon the optical rotation and the amino and ammonia nitrogen content of the hydrolyzates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000121"}
{"pmid": "21000122", "title": "The effect of varying the conditions of heating casein with sulfuric acid upon the yields and optical rotations of the basic amino acids.", "content": "The effect of varying the conditions of heating casein with sulfuric acid upon the yields and optical rotations of the basic amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000122"}
{"pmid": "21000123", "title": "Amino acids in turtle egg.", "content": "Amino acids in turtle egg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000123"}
{"pmid": "21000124", "title": "Rapid photocolorimetric micro procedure for blood sugar using copper reduction with perchloric acid deproteinized filtrates.", "content": "Rapid photocolorimetric micro procedure for blood sugar using copper reduction with perchloric acid deproteinized filtrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000124"}
{"pmid": "21000125", "title": "A new method for the preparation of basic amino acid concentrates from protein hydrolyzates.", "content": "A new method for the preparation of basic amino acid concentrates from protein hydrolyzates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000125"}
{"pmid": "21000126", "title": "The estimation of glycogen in whole blood and white blood cells.", "content": "The estimation of glycogen in whole blood and white blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000126"}
{"pmid": "21000127", "title": "Precipitation of riboflavin from aqueous solution by bacteriological reduction.", "content": "Precipitation of riboflavin from aqueous solution by bacteriological reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000127"}
{"pmid": "21000128", "title": "Determination of pentose in the presence of large quantities of glucose.", "content": "Determination of pentose in the presence of large quantities of glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000128"}
{"pmid": "21000129", "title": "Oxalacetic and pyruvic carboxylases in some dicotyledonous plants.", "content": "Oxalacetic and pyruvic carboxylases in some dicotyledonous plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000129"}
{"pmid": "21000130", "title": "The enzymatic desamination, dephosphorylation and degradation of nucleic acids to dialyzable substances.", "content": "The enzymatic desamination, dephosphorylation and degradation of nucleic acids to dialyzable substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000130"}
{"pmid": "21000131", "title": "Mutant strains of Neurospora requiring nicotinamide or related compounds for growth.", "content": "Mutant strains of Neurospora requiring nicotinamide or related compounds for growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000131"}
{"pmid": "21000132", "title": "Physical and chemical studies on Southern bean mosaic virus; crystallization by dialysis.", "content": "Physical and chemical studies on Southern bean mosaic virus; crystallization by dialysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000132"}
{"pmid": "21000133", "title": "Physical and chemical studies on Southern bean mosaic virus; electrophoretic and nucleic acid studies.", "content": "Physical and chemical studies on Southern bean mosaic virus; electrophoretic and nucleic acid studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000133"}
{"pmid": "21000134", "title": "The effect of the variation of ionic strength on the electrophoretic analysis of bovine plasma.", "content": "The effect of the variation of ionic strength on the electrophoretic analysis of bovine plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000134"}
{"pmid": "21000135", "title": "Relation of synthetic folic acid to niacin deficiency in dogs.", "content": "Relation of synthetic folic acid to niacin deficiency in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000135"}
{"pmid": "21000136", "title": "Failure to demonstrate wrist stiffness in guinea pigs receiving skim milk diets.", "content": "Failure to demonstrate wrist stiffness in guinea pigs receiving skim milk diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000136"}
{"pmid": "21000137", "title": "Behavior of phytofluene in the animal body.", "content": "Behavior of phytofluene in the animal body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000137"}
{"pmid": "21000138", "title": "On the identity of oxybiotin with O-heterobiotin.", "content": "On the identity of oxybiotin with O-heterobiotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000138"}
{"pmid": "21000139", "title": "Deethylation of N,N-diethyl-p-aminoazobenzene in the rat.", "content": "Deethylation of N,N-diethyl-p-aminoazobenzene in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000139"}
{"pmid": "21000140", "title": "Thiones and thials.", "content": "Thiones and thials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000140"}
{"pmid": "21000141", "title": "Fundamental principles of condensation polymerization.", "content": "Fundamental principles of condensation polymerization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000141"}
{"pmid": "21000142", "title": "The status of plant-growth substances and herbicides.", "content": "The status of plant-growth substances and herbicides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000142"}
{"pmid": "21000143", "title": "The sulfurization of unsaturated compounds.", "content": "The sulfurization of unsaturated compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000143"}
{"pmid": "21000144", "title": "The adsorption wave.", "content": "The adsorption wave.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000144"}
{"pmid": "21000145", "title": "The sulfenic acids and their derivatives.", "content": "The sulfenic acids and their derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000145"}
{"pmid": "21000146", "title": "The dissociation of strong electrolytes.", "content": "The dissociation of strong electrolytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000146"}
{"pmid": "21000148", "title": "Outline of the history of dental articulators and related development of engineered artificial teeth.", "content": "Outline of the history of dental articulators and related development of engineered artificial teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000148"}
{"pmid": "21000147", "title": "Methods of prescribing penicillin for oral infection.", "content": "Methods of prescribing penicillin for oral infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000147"}
{"pmid": "21000149", "title": "Nitrous oxide analgesia.", "content": "Nitrous oxide analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000149"}
{"pmid": "21000150", "title": "Periodontal disease.", "content": "Periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000150"}
{"pmid": "21000151", "title": "From diagnosis to cure; actual case.", "content": "From diagnosis to cure; actual case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000151"}
{"pmid": "21000152", "title": "NEW miniature magnifier. Mini-Mag.", "content": "NEW miniature magnifier. Mini-Mag.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000152"}
{"pmid": "21000153", "title": "The roofless denture.", "content": "The roofless denture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000153"}
{"pmid": "21000155", "title": "BINOCULAR eye loupes.", "content": "BINOCULAR eye loupes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000155"}
{"pmid": "21000154", "title": "Studies of wear, arrangement and occlusion of the dentitions of humans and animals and their relationship to orthodontia, periodontia and prosthodontia.", "content": "Studies of wear, arrangement and occlusion of the dentitions of humans and animals and their relationship to orthodontia, periodontia and prosthodontia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000154"}
{"pmid": "21000156", "title": "Practice management and post problems.", "content": "Practice management and post problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000156"}
{"pmid": "21000157", "title": "Balanced anaesthesia in oral and facio-maxillary surgery.", "content": "Balanced anaesthesia in oral and facio-maxillary surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000157"}
{"pmid": "21000158", "title": "Cure of an old depressed malar with trismus present.", "content": "Cure of an old depressed malar with trismus present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000158"}
{"pmid": "21000159", "title": "Mouth rehabilitation and bite raising.", "content": "Mouth rehabilitation and bite raising.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000159"}
{"pmid": "21000160", "title": "Penicillin in dental and oral surgery.", "content": "Penicillin in dental and oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000160"}
{"pmid": "21000161", "title": "Maxillary block anesthesia.", "content": "Maxillary block anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000161"}
{"pmid": "21000162", "title": "Clinical efficacy of powder and paste dentifrices.", "content": "Clinical efficacy of powder and paste dentifrices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000162"}
{"pmid": "21000163", "title": "Methods of payment for dental care.", "content": "Methods of payment for dental care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000163"}
{"pmid": "21000164", "title": "Chemical changes in the teeth after eruption.", "content": "Chemical changes in the teeth after eruption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000164"}
{"pmid": "21000166", "title": "Further studies of exposed pulps as portal of entry for poliomyelitis virus.", "content": "Further studies of exposed pulps as portal of entry for poliomyelitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000166"}
{"pmid": "21000165", "title": "Focal infection in relation to rheumatic diseases; a critical appraisal.", "content": "Focal infection in relation to rheumatic diseases; a critical appraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000165"}
{"pmid": "21000167", "title": "Toothbrushing habits of 405 persons.", "content": "Toothbrushing habits of 405 persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000167"}
{"pmid": "21000168", "title": "Thermal control apparatus for dental drilling.", "content": "Thermal control apparatus for dental drilling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000168"}
{"pmid": "21000169", "title": "Absenteeism in Tennessee industrial plants caused by diseases of the teeth and gums.", "content": "Absenteeism in Tennessee industrial plants caused by diseases of the teeth and gums.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000169"}
{"pmid": "21000170", "title": "The cold slab in silicate ceramic restorations.", "content": "The cold slab in silicate ceramic restorations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000170"}
{"pmid": "21000171", "title": "Dental caries (DMF) experienced by relocated children exposed to water containing fluorine.", "content": "Dental caries (DMF) experienced by relocated children exposed to water containing fluorine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000171"}
{"pmid": "21000172", "title": "Dental status of 71,015 naval personnel at first examination in 1942.", "content": "Dental status of 71,015 naval personnel at first examination in 1942.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000172"}
{"pmid": "21000174", "title": "The reaction of dental pulps to silicate cements.", "content": "The reaction of dental pulps to silicate cements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000174"}
{"pmid": "21000173", "title": "Isopropyl alcohol.", "content": "Isopropyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000173"}
{"pmid": "21000175", "title": "The use of acrylic resins in restorative dentistry.", "content": "The use of acrylic resins in restorative dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000175"}
{"pmid": "21000176", "title": "Inlay impressions; using a closed-bite technic.", "content": "Inlay impressions; using a closed-bite technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000176"}
{"pmid": "21000177", "title": "Dimensional stability of alginate impression materials.", "content": "Dimensional stability of alginate impression materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000177"}
{"pmid": "21000179", "title": "Dentistry at Cabanatuan War Prison Camp No. 1, in the Philippine Islands.", "content": "Dentistry at Cabanatuan War Prison Camp No. 1, in the Philippine Islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000179"}
{"pmid": "21000178", "title": "The temporomandibular joint; theory of reflex controlled nonlever action of the mandible.", "content": "The temporomandibular joint; theory of reflex controlled nonlever action of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000178"}
{"pmid": "21000180", "title": "The prognosis of marginal gingival atrophy.", "content": "The prognosis of marginal gingival atrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000180"}
{"pmid": "21000181", "title": "Preliminary report on penicillin in root therapy.", "content": "Preliminary report on penicillin in root therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000181"}
{"pmid": "21000182", "title": "Products of human blood fractionation and their uses in dentistry.", "content": "Products of human blood fractionation and their uses in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000182"}
{"pmid": "21000183", "title": "Idiosyncrasy to sulfanilamide.", "content": "Idiosyncrasy to sulfanilamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000183"}
{"pmid": "21000184", "title": "Use of female sex hormone in the treatment of chronic desquamative gingivitis.", "content": "Use of female sex hormone in the treatment of chronic desquamative gingivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000184"}
{"pmid": "21000185", "title": "The effects of various numbers of topical applications of sodium fluoride.", "content": "The effects of various numbers of topical applications of sodium fluoride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000185"}
{"pmid": "21000186", "title": "Shrinkage during casting of gold and gold alloys.", "content": "Shrinkage during casting of gold and gold alloys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000186"}
{"pmid": "21000188", "title": "Time required to treat dental defects in 71,015 naval personnel, with regional and age variations.", "content": "Time required to treat dental defects in 71,015 naval personnel, with regional and age variations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000188"}
{"pmid": "21000187", "title": "Pain and its significance in oral surgery.", "content": "Pain and its significance in oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000187"}
{"pmid": "21000189", "title": "Fibrin foam as a clinical aid in dental surgery.", "content": "Fibrin foam as a clinical aid in dental surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000189"}
{"pmid": "21000190", "title": "Glossodynia; a study of idiopathic orolingual pain.", "content": "Glossodynia; a study of idiopathic orolingual pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000190"}
{"pmid": "21000191", "title": "Trifacial neuralgia or tic douloureux.", "content": "Trifacial neuralgia or tic douloureux.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000191"}
{"pmid": "21000194", "title": "A comparison between grinding of occlusion of natural teeth and artificial dentures.", "content": "A comparison between grinding of occlusion of natural teeth and artificial dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000194"}
{"pmid": "21000192", "title": "The normal mouth; some non-pathologic variations.", "content": "The normal mouth; some non-pathologic variations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000192"}
{"pmid": "21000193", "title": "Teeth, guinea pigs and dentistry.", "content": "Teeth, guinea pigs and dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000193"}
{"pmid": "21000196", "title": "An experimental survey on the relation of sodium fluoride to enamel decalcification.", "content": "An experimental survey on the relation of sodium fluoride to enamel decalcification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000196"}
{"pmid": "21000195", "title": "The dental problem in New Zealand in relation to the modern conception of health services.", "content": "The dental problem in New Zealand in relation to the modern conception of health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000195"}
{"pmid": "21000197", "title": "Penicillin cream for the treatment of Vincent's stomatitis.", "content": "Penicillin cream for the treatment of Vincent's stomatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000197"}
{"pmid": "21000198", "title": "A labial bar partial denture.", "content": "A labial bar partial denture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000198"}
{"pmid": "21000199", "title": "Eczematous and pigmentary lichenoid dermatitis; atypical lichen planus; preliminary report.", "content": "Eczematous and pigmentary lichenoid dermatitis; atypical lichen planus; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000199"}
{"pmid": "21000200", "title": "Neurodermatitic reaction.", "content": "Neurodermatitic reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000200"}
{"pmid": "21000201", "title": "A study on ulcus phagedenicum cutis.", "content": "A study on ulcus phagedenicum cutis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000201"}
{"pmid": "21000202", "title": "Vitamin B complex in the treatment of lichenoid dermatitis.", "content": "Vitamin B complex in the treatment of lichenoid dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000202"}
{"pmid": "21000203", "title": "Progressive recurrent dermatofibroma (Darier-Ferrand); anatomoclinical study.", "content": "Progressive recurrent dermatofibroma (Darier-Ferrand); anatomoclinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000203"}
{"pmid": "21000204", "title": "Keratosis blenorrhagica.", "content": "Keratosis blenorrhagica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000204"}
{"pmid": "21000205", "title": "The use of vioform in local dermatologic therapy.", "content": "The use of vioform in local dermatologic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000205"}
{"pmid": "21000206", "title": "Discoid and disseminated lupus erythematosus.", "content": "Discoid and disseminated lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000206"}
{"pmid": "21000207", "title": "A case for diagnosis (leukemoid; contact dermatitis?).", "content": "A case for diagnosis (leukemoid; contact dermatitis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000207"}
{"pmid": "21000208", "title": "A case for diagnosis (superficial epitheliomatosis?).", "content": "A case for diagnosis (superficial epitheliomatosis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000208"}
{"pmid": "21000209", "title": "A case for diagnosis (lupus pernio; sarcoid?).", "content": "A case for diagnosis (lupus pernio; sarcoid?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000209"}
{"pmid": "21000211", "title": "Blastomycosis.", "content": "Blastomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000211"}
{"pmid": "21000210", "title": "Lymphoblastoma.", "content": "Lymphoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000210"}
{"pmid": "21000213", "title": "Epidermolysis bullosa with formation of scars and milia.", "content": "Epidermolysis bullosa with formation of scars and milia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000213"}
{"pmid": "21000212", "title": "Lichen ruber moniliformis Kaposi.", "content": "Lichen ruber moniliformis Kaposi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000212"}
{"pmid": "21000214", "title": "Chronic lymphangitis.", "content": "Chronic lymphangitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000214"}
{"pmid": "21000215", "title": "Urticaria due to cold.", "content": "Urticaria due to cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000215"}
{"pmid": "21000216", "title": "Dermatitis medicamentosa (fixed eruption due to arsenic).", "content": "Dermatitis medicamentosa (fixed eruption due to arsenic).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000216"}
{"pmid": "21000217", "title": "Urticaria pigmentosa.", "content": "Urticaria pigmentosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000217"}
{"pmid": "21000218", "title": "Dermatitis lichenoides chronica atrophicans (Csillag).", "content": "Dermatitis lichenoides chronica atrophicans (Csillag).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000218"}
{"pmid": "21000219", "title": "Dermatitis medicamentosa (iodide).", "content": "Dermatitis medicamentosa (iodide).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000219"}
{"pmid": "21000220", "title": "Moniliasis.", "content": "Moniliasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000220"}
{"pmid": "21000221", "title": "A case for diagnosis (Moeller's glossitis? glossitis due to vitamin B deficiency; glossitis due to phenobarbital?).", "content": "A case for diagnosis (Moeller's glossitis? glossitis due to vitamin B deficiency; glossitis due to phenobarbital?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000221"}
{"pmid": "21000222", "title": "Urticaria due to cold (improved with histamine injections).", "content": "Urticaria due to cold (improved with histamine injections).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000222"}
{"pmid": "21000223", "title": "Ainhum.", "content": "Ainhum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000223"}
{"pmid": "21000224", "title": "Sarcoid (healed) of skin, lungs, bones, larynx and kidneys?", "content": "Sarcoid (healed) of skin, lungs, bones, larynx and kidneys?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000224"}
{"pmid": "21000225", "title": "Miliary lupoid of the face; generalized lichenoid and eczematoid dermatitis resembling mycosis fungoides.", "content": "Miliary lupoid of the face; generalized lichenoid and eczematoid dermatitis resembling mycosis fungoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000225"}
{"pmid": "21000226", "title": "Chronic lymphangitis and chronic recurrent angioneurotic edema of the face.", "content": "Chronic lymphangitis and chronic recurrent angioneurotic edema of the face.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000226"}
{"pmid": "21000227", "title": "A case for diagnosis (lipoidosis?).", "content": "A case for diagnosis (lipoidosis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000227"}
{"pmid": "21000228", "title": "A case for diagnosis (nevus?).", "content": "A case for diagnosis (nevus?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000228"}
{"pmid": "21000229", "title": "Unilateral acrodermatitis chronica atrophicans.", "content": "Unilateral acrodermatitis chronica atrophicans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000229"}
{"pmid": "21000230", "title": "A case for diagnosis (rosacea; rosacea-like tuberculid?).", "content": "A case for diagnosis (rosacea; rosacea-like tuberculid?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000230"}
{"pmid": "21000231", "title": "Subcutaneous recurrent effusion.", "content": "Subcutaneous recurrent effusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000231"}
{"pmid": "21000232", "title": "The application of the principles of statistical analysis to the biological assay of hormones.", "content": "The application of the principles of statistical analysis to the biological assay of hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000232"}
{"pmid": "21000233", "title": "Estrogen in late pregnancy mare serum and ovarian inhibition.", "content": "Estrogen in late pregnancy mare serum and ovarian inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000233"}
{"pmid": "21000234", "title": "The nature of circulating estrogen; lipoprotein-bound estrogen in human plasma.", "content": "The nature of circulating estrogen; lipoprotein-bound estrogen in human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000234"}
{"pmid": "21000236", "title": "The effect of steroids related to the cortical hormones and of stilbestrol on the adrenalectomized guinea pig.", "content": "The effect of steroids related to the cortical hormones and of stilbestrol on the adrenalectomized guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000236"}
{"pmid": "21000235", "title": "Fluctuations in weight, hematocrit and plasma protein with the menstrual cycle.", "content": "Fluctuations in weight, hematocrit and plasma protein with the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000235"}
{"pmid": "21000237", "title": "Adrenal function in pregnancy.", "content": "Adrenal function in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000237"}
{"pmid": "21000238", "title": "Stimulating the sex drive of bovine males in artificial insemination.", "content": "Stimulating the sex drive of bovine males in artificial insemination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000238"}
{"pmid": "21000239", "title": "Special problems of poor surgical risks among the aged.", "content": "Special problems of poor surgical risks among the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000239"}
{"pmid": "21000240", "title": "Diet in older people.", "content": "Diet in older people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000240"}
{"pmid": "21000241", "title": "Ambulatory illness in older persons.", "content": "Ambulatory illness in older persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000241"}
{"pmid": "21000242", "title": "The mental hygiene of aging.", "content": "The mental hygiene of aging.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000242"}
{"pmid": "21000244", "title": "Mortality and life expectancy in the United States since 1900.", "content": "Mortality and life expectancy in the United States since 1900.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000244"}
{"pmid": "21000243", "title": "Dermatitis in the aged.", "content": "Dermatitis in the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000243"}
{"pmid": "21000256", "title": "Further observations on the effect of benzene on a strain of myeloid chloroleukemia in mice and on changes produced in the leukemic cells by the chemical.", "content": "Further observations on the effect of benzene on a strain of myeloid chloroleukemia in mice and on changes produced in the leukemic cells by the chemical.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000256"}
{"pmid": "21000257", "title": "Cellular changes produced by extracts of human organs.", "content": "Cellular changes produced by extracts of human organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000257"}
{"pmid": "21000258", "title": "Monocytic leukemia and tuberculosis.", "content": "Monocytic leukemia and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000258"}
{"pmid": "21000259", "title": "Plasma cell leukemia.", "content": "Plasma cell leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000259"}
{"pmid": "21000260", "title": "Morphological examination of the blood and sternal marrow on nine patients treated with thiouracil.", "content": "Morphological examination of the blood and sternal marrow on nine patients treated with thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000260"}
{"pmid": "21000261", "title": "Sternal marrow studies in thyrotoxicosis treated with thiouracil and review of literature regarding thiouracil effects on blood.", "content": "Sternal marrow studies in thyrotoxicosis treated with thiouracil and review of literature regarding thiouracil effects on blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000261"}
{"pmid": "21000262", "title": "The effect of thiouracil on leukemia.", "content": "The effect of thiouracil on leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000262"}
{"pmid": "21000263", "title": "Chemotherapy of leukemia and related diseases.", "content": "Chemotherapy of leukemia and related diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000263"}
{"pmid": "21000264", "title": "Postgraduate instruction in the future of homeopathy.", "content": "Postgraduate instruction in the future of homeopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000264"}
{"pmid": "21000265", "title": "The relationship of geriatrics, pre-clinical medicine and homeopathy.", "content": "The relationship of geriatrics, pre-clinical medicine and homeopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000265"}
{"pmid": "21000266", "title": "A few little-used valuable remedies.", "content": "A few little-used valuable remedies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000266"}
{"pmid": "21000267", "title": "Two congenital deformities. [persistent cloaca].", "content": "Two congenital deformities. [persistent cloaca].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000267"}
{"pmid": "21000269", "title": "Chronic and migraine headache.", "content": "Chronic and migraine headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000269"}
{"pmid": "21000270", "title": "Glandular dystrophy.", "content": "Glandular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000270"}
{"pmid": "21000268", "title": "Can homeopathy help in psychosomatic sickness?", "content": "Can homeopathy help in psychosomatic sickness?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000268"}
{"pmid": "21000271", "title": "Toxemia of pregnancy.", "content": "Toxemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000271"}
{"pmid": "21000272", "title": "Intradermal spread of vital dye in anaphylaxis and bacterial allergy.", "content": "Intradermal spread of vital dye in anaphylaxis and bacterial allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000272"}
{"pmid": "21000273", "title": "The action of urea and some of its derivatives on bacteria; bacteriostatic and bactericidal effects of urea and urethane.", "content": "The action of urea and some of its derivatives on bacteria; bacteriostatic and bactericidal effects of urea and urethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000273"}
{"pmid": "21000274", "title": "The action of urea and some of its derivatives on bacteria; the antibacterial activity of combinations of urea and urethane with sulfonamides and the effect of the carbamates on para-amino-benzoic acid and on the solubility of sulfonamides.", "content": "The action of urea and some of its derivatives on bacteria; the antibacterial activity of combinations of urea and urethane with sulfonamides and the effect of the carbamates on para-amino-benzoic acid and on the solubility of sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000274"}
{"pmid": "21000275", "title": "The action of urea and some of its derivatives on bacteria; the effect of combining urea or urethane with penicillin on mixed cultures of gram-positive and gram-negative bacteria.", "content": "The action of urea and some of its derivatives on bacteria; the effect of combining urea or urethane with penicillin on mixed cultures of gram-positive and gram-negative bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000275"}
{"pmid": "21000276", "title": "Studies on antireticular cytotoxic serum; introduction and review of the literature.", "content": "Studies on antireticular cytotoxic serum; introduction and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000276"}
{"pmid": "21000277", "title": "Studies on antireticular cytotoxic serum; preparation and titration of the serum and study of its serological properties.", "content": "Studies on antireticular cytotoxic serum; preparation and titration of the serum and study of its serological properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000277"}
{"pmid": "21000278", "title": "Studies on antireticular cytotoxic serum; effect of ACS on the healing of experimentally produced fractures in rabbits.", "content": "Studies on antireticular cytotoxic serum; effect of ACS on the healing of experimentally produced fractures in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000278"}
{"pmid": "21000279", "title": "Passive protection of the central nervous system of mice against viruses that pursue the pathway of the olfactory nerves after intranasal instillation; vesicular stomatitis and St. Louis encephalitis.", "content": "Passive protection of the central nervous system of mice against viruses that pursue the pathway of the olfactory nerves after intranasal instillation; vesicular stomatitis and St. Louis encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000279"}
{"pmid": "21000280", "title": "Missed cases and contact carriers among nasal carriers of beta hemolytic streptococci.", "content": "Missed cases and contact carriers among nasal carriers of beta hemolytic streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000280"}
{"pmid": "21000281", "title": "Quantitative studies on the neutralization of pathogenic agents in tissues by circulating antibodies; quantitative determination of the effect of the substances modifying capillary permeability with the aid of indirect test.", "content": "Quantitative studies on the neutralization of pathogenic agents in tissues by circulating antibodies; quantitative determination of the effect of the substances modifying capillary permeability with the aid of indirect test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000281"}
{"pmid": "21000282", "title": "Production of types a, b, c, d, e and f, H. influenzae antibody, for diagnostic and therapeutic purposes.", "content": "Production of types a, b, c, d, e and f, H. influenzae antibody, for diagnostic and therapeutic purposes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000282"}
{"pmid": "21000283", "title": "Volatile hydrides of toxicological importance.", "content": "Volatile hydrides of toxicological importance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000283"}
{"pmid": "21000284", "title": "Respiratory air flow characteristics and their relation to certain lung conditions occurring in industry.", "content": "Respiratory air flow characteristics and their relation to certain lung conditions occurring in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000284"}
{"pmid": "21000285", "title": "Delayed chemical pneumonitis occurring in workers exposed to beryllium compounds.", "content": "Delayed chemical pneumonitis occurring in workers exposed to beryllium compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000285"}
{"pmid": "21000286", "title": "Radium dial painting; medical status of workers.", "content": "Radium dial painting; medical status of workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000286"}
{"pmid": "21000287", "title": "The determination of free silica in industrial dust.", "content": "The determination of free silica in industrial dust.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000287"}
{"pmid": "21000288", "title": "Tellurium; the toxicity of ingested elementary tellurium for rats and rat tissues.", "content": "Tellurium; the toxicity of ingested elementary tellurium for rats and rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000288"}
{"pmid": "21000289", "title": "Lobar pneumonia in the shipbuilding industry; a review of five hundred and forty-four cases over a one-year period.", "content": "Lobar pneumonia in the shipbuilding industry; a review of five hundred and forty-four cases over a one-year period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000289"}
{"pmid": "21000290", "title": "Determination of chlorinated hydrocarbon vapors in air.", "content": "Determination of chlorinated hydrocarbon vapors in air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000290"}
{"pmid": "21000291", "title": "Psychoneurosis and industry.", "content": "Psychoneurosis and industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000291"}
{"pmid": "21000292", "title": "Significance of industrial cancer in the problem of cancer.", "content": "Significance of industrial cancer in the problem of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000292"}
{"pmid": "21000293", "title": "Rehabilitation of the sick and injured.", "content": "Rehabilitation of the sick and injured.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000293"}
{"pmid": "21000294", "title": "Tuberculosis control in industry; results from 1941 to 1945.", "content": "Tuberculosis control in industry; results from 1941 to 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000294"}
{"pmid": "21000295", "title": "Sprain or momentary dislocation of the talus?", "content": "Sprain or momentary dislocation of the talus?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000295"}
{"pmid": "21000296", "title": "Treatment of wounds.", "content": "Treatment of wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000296"}
{"pmid": "21000298", "title": "Nature and science.", "content": "Nature and science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000298"}
{"pmid": "21000299", "title": "The diagnosis and treatment of rheumatoid arthritis.", "content": "The diagnosis and treatment of rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000299"}
{"pmid": "21000297", "title": "Values and problems in industrial recreation.", "content": "Values and problems in industrial recreation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000297"}
{"pmid": "21000300", "title": "The management of peptic ulcer.", "content": "The management of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000300"}
{"pmid": "21000301", "title": "The British Red Cross in North-West Europe.", "content": "The British Red Cross in North-West Europe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000301"}
{"pmid": "21000302", "title": "Craniopharyngioma.", "content": "Craniopharyngioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000302"}
{"pmid": "21000303", "title": "Uses and abuses of penicillin.", "content": "Uses and abuses of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000303"}
{"pmid": "21000304", "title": "DISCUSSION of the plan for the integration of provincial health services.", "content": "DISCUSSION of the plan for the integration of provincial health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000304"}
{"pmid": "21000305", "title": "The pathology of chronic thyroiditis.", "content": "The pathology of chronic thyroiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000305"}
{"pmid": "21000306", "title": "Acute pelvic peritonitis.", "content": "Acute pelvic peritonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000306"}
{"pmid": "21000307", "title": "The medical future of tuberculosis control.", "content": "The medical future of tuberculosis control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000307"}
{"pmid": "21000309", "title": "A study of the relationship of resistance, allergy, antibody and tissue reactivity in tuberculosis to the components of the tubercle bacillus.", "content": "A study of the relationship of resistance, allergy, antibody and tissue reactivity in tuberculosis to the components of the tubercle bacillus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000309"}
{"pmid": "21000308", "title": "Air borne infection in tuberculosis.", "content": "Air borne infection in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000308"}
{"pmid": "21000310", "title": "Chemotherapy of tuberculosis.", "content": "Chemotherapy of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000310"}
{"pmid": "21000311", "title": "Social and economic hindrances to program for prevention of tuberculosis.", "content": "Social and economic hindrances to program for prevention of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000311"}
{"pmid": "21000312", "title": "A review of certain principles in management of thoracic war wounds.", "content": "A review of certain principles in management of thoracic war wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000312"}
{"pmid": "21000313", "title": "Plombage in the treatment of pulmonary tuberculosis; a preliminary report of use following unsuccessful thoraco-plasty.", "content": "Plombage in the treatment of pulmonary tuberculosis; a preliminary report of use following unsuccessful thoraco-plasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000313"}
{"pmid": "21000314", "title": "Putting miniature films to work; follow-up by health department.", "content": "Putting miniature films to work; follow-up by health department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000314"}
{"pmid": "21000315", "title": "Planning and organization of a case-finding program.", "content": "Planning and organization of a case-finding program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000315"}
{"pmid": "21000316", "title": "Modern concepts of rehabilitation.", "content": "Modern concepts of rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000316"}
{"pmid": "21000319", "title": "The coccidioidin skin test in the Panama Canal Zone; results of a brief survey in tuberculous and non-tuberculous patients.", "content": "The coccidioidin skin test in the Panama Canal Zone; results of a brief survey in tuberculous and non-tuberculous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000319"}
{"pmid": "21000322", "title": "Practical application of newer methods in control of rodent and insect pests.", "content": "Practical application of newer methods in control of rodent and insect pests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000322"}
{"pmid": "21000321", "title": "California public health laboratories and their services to physicians.", "content": "California public health laboratories and their services to physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000321"}
{"pmid": "21000324", "title": "Current methods for the study and treatment of sterility.", "content": "Current methods for the study and treatment of sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000324"}
{"pmid": "21000325", "title": "Program of the Cancer Commission.", "content": "Program of the Cancer Commission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000325"}
{"pmid": "21000326", "title": "The physician and medical legal phases in the adoption of children.", "content": "The physician and medical legal phases in the adoption of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000326"}
{"pmid": "21000327", "title": "Hypotension (hypopiesia).", "content": "Hypotension (hypopiesia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000327"}
{"pmid": "21000328", "title": "Colles' fracture.", "content": "Colles' fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000328"}
{"pmid": "21000329", "title": "Use of the life chart in psychiatric consultation.", "content": "Use of the life chart in psychiatric consultation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000329"}
{"pmid": "21000330", "title": "Some common errors of the general physician in dealing with foreign body injuries of the eye.", "content": "Some common errors of the general physician in dealing with foreign body injuries of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000330"}
{"pmid": "21000331", "title": "Common intestinal parasites and their treatment.", "content": "Common intestinal parasites and their treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000331"}
{"pmid": "21000332", "title": "The treatment of subacute bacterial endocarditis.", "content": "The treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000332"}
{"pmid": "21000333", "title": "GONORRHEA in women.", "content": "GONORRHEA in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000333"}
{"pmid": "21000334", "title": "HEMORRHOIDECTOMY by incision and dissection.", "content": "HEMORRHOIDECTOMY by incision and dissection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000334"}
{"pmid": "21000335", "title": "Recurrent appendicitis and lesions of the urogenital tract; differential diagnosis.", "content": "Recurrent appendicitis and lesions of the urogenital tract; differential diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000335"}
{"pmid": "21000336", "title": "Recent developments in bronchial asthma therapy.", "content": "Recent developments in bronchial asthma therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000336"}
{"pmid": "21000337", "title": "The private practitioner and the school health program.", "content": "The private practitioner and the school health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000337"}
{"pmid": "21000338", "title": "The treatment of diabetic coma (severe ketosis).", "content": "The treatment of diabetic coma (severe ketosis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000338"}
{"pmid": "21000339", "title": "An unusual type of metatarsal osteoporosis.", "content": "An unusual type of metatarsal osteoporosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000339"}
{"pmid": "21000341", "title": "SHOCK.", "content": "SHOCK.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000341"}
{"pmid": "21000340", "title": "Surgical gastro-intestinal tuberculosis in cases of pulmonary tuberculosis.", "content": "Surgical gastro-intestinal tuberculosis in cases of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000340"}
{"pmid": "21000342", "title": "[TUBERCULOSIS pericarditis].", "content": "[TUBERCULOSIS pericarditis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000342"}
{"pmid": "21000343", "title": "[Angina pectoris].", "content": "[Angina pectoris].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000343"}
{"pmid": "21000344", "title": "[Epidermoid tumour].", "content": "[Epidermoid tumour].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000344"}
{"pmid": "21000345", "title": "Kwashiorkor.", "content": "Kwashiorkor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000345"}
{"pmid": "21000346", "title": "An islet method of wiring fracture of the mandible.", "content": "An islet method of wiring fracture of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000346"}
{"pmid": "21000347", "title": "Penicillin in syphilis.", "content": "Penicillin in syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000347"}
{"pmid": "21000348", "title": "[Carcinoma of the fundus of the stomach].", "content": "[Carcinoma of the fundus of the stomach].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000348"}
{"pmid": "21000349", "title": "Stenosis of the left primary bronchus following disseminated tuberculous infiltration of the left lung.", "content": "Stenosis of the left primary bronchus following disseminated tuberculous infiltration of the left lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000349"}
{"pmid": "21000350", "title": "[Carotid sinus syndrome].", "content": "[Carotid sinus syndrome].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000350"}
{"pmid": "21000351", "title": "Cardiovascular catheterization as an aid in diagnosis of abnormal cardiovascular communications.", "content": "Cardiovascular catheterization as an aid in diagnosis of abnormal cardiovascular communications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000351"}
{"pmid": "21000352", "title": "Psychiatric reactions to aerial combat and their sequelae.", "content": "Psychiatric reactions to aerial combat and their sequelae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000352"}
{"pmid": "21000353", "title": "Present status of electric shock therapy.", "content": "Present status of electric shock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000353"}
{"pmid": "21000354", "title": "Psychogenic deafness.", "content": "Psychogenic deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000354"}
{"pmid": "21000355", "title": "Problems of prepayment for medical service.", "content": "Problems of prepayment for medical service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000355"}
{"pmid": "21000356", "title": "Problems related to the medical care of veterans.", "content": "Problems related to the medical care of veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000356"}
{"pmid": "21000357", "title": "Tuberculosis in the African; the problem and its solution.", "content": "Tuberculosis in the African; the problem and its solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000357"}
{"pmid": "21000358", "title": "Studies in pigmentation.", "content": "Studies in pigmentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000358"}
{"pmid": "21000359", "title": "A discussion of measures likely to diminish the risk of food-borne infection.", "content": "A discussion of measures likely to diminish the risk of food-borne infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000359"}
{"pmid": "21000360", "title": "Some aspects of the sociology of the medical profession.", "content": "Some aspects of the sociology of the medical profession.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000360"}
{"pmid": "21000361", "title": "Anaesthetic convulsions.", "content": "Anaesthetic convulsions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000361"}
{"pmid": "21000362", "title": "The recent epidemiology of typhoid in Ireland.", "content": "The recent epidemiology of typhoid in Ireland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000362"}
{"pmid": "21000363", "title": "The epidemiology of enteritis of infants.", "content": "The epidemiology of enteritis of infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000363"}
{"pmid": "21000364", "title": "The incidence of rickets in Dublin.", "content": "The incidence of rickets in Dublin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000364"}
{"pmid": "21000368", "title": "Pulmonary sarcoidosis.", "content": "Pulmonary sarcoidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000368"}
{"pmid": "21000371", "title": "[Gonorrhea.].", "content": "[Gonorrhea.].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000371"}
{"pmid": "21000369", "title": "The Rh blood factors.", "content": "The Rh blood factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000369"}
{"pmid": "21000370", "title": "X-ray in evacuation hospitals.", "content": "X-ray in evacuation hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000370"}
{"pmid": "21000372", "title": "Recent advances in ophthalmology.", "content": "Recent advances in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000372"}
{"pmid": "21000373", "title": "Benadryl; a preliminary report on its use in 39 patients.", "content": "Benadryl; a preliminary report on its use in 39 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000373"}
{"pmid": "21000374", "title": "Available antibiotic preparations and their toxicity.", "content": "Available antibiotic preparations and their toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000374"}
{"pmid": "21000375", "title": "Penicillin therapy in neurology and psychiatry.", "content": "Penicillin therapy in neurology and psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000375"}
{"pmid": "21000376", "title": "The University of Texas Medical Branch hospital service.", "content": "The University of Texas Medical Branch hospital service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000376"}
{"pmid": "21000377", "title": "An incision for exposure of the proximal one-third of the humerus.", "content": "An incision for exposure of the proximal one-third of the humerus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000377"}
{"pmid": "21000378", "title": "Parenteral feeding of the patient with cancer of the colon.", "content": "Parenteral feeding of the patient with cancer of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000378"}
{"pmid": "21000367", "title": "A new concept of proctology.", "content": "A new concept of proctology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000367"}
{"pmid": "21000365", "title": "Homeopathic application in pediatrics.", "content": "Homeopathic application in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000365"}
{"pmid": "21000366", "title": "Homeopathy and tumors; cases.", "content": "Homeopathy and tumors; cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000366"}
{"pmid": "21000379", "title": "Problems in the surgery of traumatic aneurysm with report of an instructive case.", "content": "Problems in the surgery of traumatic aneurysm with report of an instructive case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000379"}
{"pmid": "21000380", "title": "The physiological basis of asthma.", "content": "The physiological basis of asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000380"}
{"pmid": "21000381", "title": "Some extrinsic factors in tumor formation.", "content": "Some extrinsic factors in tumor formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000381"}
{"pmid": "21000382", "title": "Penicillin in the treatment of actinomycosis.", "content": "Penicillin in the treatment of actinomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000382"}
{"pmid": "21000383", "title": "Heat sickness.", "content": "Heat sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000383"}
{"pmid": "21000385", "title": "Toothpowder as a cause of cigarette cough.", "content": "Toothpowder as a cause of cigarette cough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000385"}
{"pmid": "21000384", "title": "Sprue.", "content": "Sprue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000384"}
{"pmid": "21000386", "title": "Scarlet fever; an epidemiologic and bacteriologic study of cases occurring in a small community.", "content": "Scarlet fever; an epidemiologic and bacteriologic study of cases occurring in a small community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000386"}
{"pmid": "21000387", "title": "Acute salpingitis due to Friedländer's bacillus.", "content": "Acute salpingitis due to Friedländer's bacillus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000387"}
{"pmid": "21000388", "title": "The cause, relief and prevention of headaches arising from contact with dynamite.", "content": "The cause, relief and prevention of headaches arising from contact with dynamite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000388"}
{"pmid": "21000389", "title": "Terminal ileitis with obstruction and abscess complicating pregnancy.", "content": "Terminal ileitis with obstruction and abscess complicating pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000389"}
{"pmid": "21000390", "title": "Acute rheumatic myocarditis.", "content": "Acute rheumatic myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000390"}
{"pmid": "21000391", "title": "Hepatoma, with portal vein invasion and thrombosis; cirrhosis of liver, alcoholic type; esophageal varices, with massive hemorrhage.", "content": "Hepatoma, with portal vein invasion and thrombosis; cirrhosis of liver, alcoholic type; esophageal varices, with massive hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000391"}
{"pmid": "21000392", "title": "Enteric infections and their sequelae.", "content": "Enteric infections and their sequelae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000392"}
{"pmid": "21000393", "title": "Surgical treatment of ascites.", "content": "Surgical treatment of ascites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000393"}
{"pmid": "21000394", "title": "Tuberculosis of the genitourinary tract among soldiers in World War II.", "content": "Tuberculosis of the genitourinary tract among soldiers in World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000394"}
{"pmid": "21000395", "title": "Acute pulmonary edema, with special reference to experimental studies.", "content": "Acute pulmonary edema, with special reference to experimental studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000395"}
{"pmid": "21000396", "title": "Embolism, superior mesenteric artery; arteriosclerosis, generalized, severe.", "content": "Embolism, superior mesenteric artery; arteriosclerosis, generalized, severe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000396"}
{"pmid": "21000397", "title": "Papillary carcinoma (Grade II A), involving upper half of bifid pelvis.", "content": "Papillary carcinoma (Grade II A), involving upper half of bifid pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000397"}
{"pmid": "21000398", "title": "Subacute bacterial endocarditis; a report of two cases successfully treated with penicillin.", "content": "Subacute bacterial endocarditis; a report of two cases successfully treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000398"}
{"pmid": "21000399", "title": "Hemostasis by thrombin and fibrin foam in suprapubic prostatectomy.", "content": "Hemostasis by thrombin and fibrin foam in suprapubic prostatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000399"}
{"pmid": "21000401", "title": "The significance of mediastinal emphysema.", "content": "The significance of mediastinal emphysema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000401"}
{"pmid": "21000400", "title": "Treatment of mental illness at home by small doses of insulin; an appraisal of results in twelve cases.", "content": "Treatment of mental illness at home by small doses of insulin; an appraisal of results in twelve cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000400"}
{"pmid": "21000403", "title": "Ewing tumor of clavicle.", "content": "Ewing tumor of clavicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000403"}
{"pmid": "21000405", "title": "Submucous lipoma of the colon.", "content": "Submucous lipoma of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000405"}
{"pmid": "21000402", "title": "Strangulation of bowel by adhesive band.", "content": "Strangulation of bowel by adhesive band.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000402"}
{"pmid": "21000404", "title": "Appendicostomy in chronic ulcerative colitis.", "content": "Appendicostomy in chronic ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000404"}
{"pmid": "21000406", "title": "Carcinoma of the colon; resection and immediate primary anastomosis.", "content": "Carcinoma of the colon; resection and immediate primary anastomosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000406"}
{"pmid": "21000407", "title": "Infectious hepatitis.", "content": "Infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000407"}
{"pmid": "21000408", "title": "The management of uncomplicated peptic ulcer.", "content": "The management of uncomplicated peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000408"}
{"pmid": "21000410", "title": "Method for the evaluation of calcium therapy by roentgenographic technic.", "content": "Method for the evaluation of calcium therapy by roentgenographic technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000410"}
{"pmid": "21000409", "title": "Complications of amebiasis.", "content": "Complications of amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000409"}
{"pmid": "21000411", "title": "Hemorrhagic vesicles and bullae of the mucous membranes of U.S. and British war prisoners in Japan, subsisting on a deficient diet.", "content": "Hemorrhagic vesicles and bullae of the mucous membranes of U.S. and British war prisoners in Japan, subsisting on a deficient diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000411"}
{"pmid": "21000412", "title": "The management of gallbladder disease.", "content": "The management of gallbladder disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000412"}
{"pmid": "21000413", "title": "Aplastic anaemia.", "content": "Aplastic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000413"}
{"pmid": "21000414", "title": "Sickle cell anemia complicated by pregnancy.", "content": "Sickle cell anemia complicated by pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000414"}
{"pmid": "21000427", "title": "Some aspects of sex endocrinology in general practice.", "content": "Some aspects of sex endocrinology in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000427"}
{"pmid": "21000428", "title": "The increase in diphtheria incidence in 1945.", "content": "The increase in diphtheria incidence in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000428"}
{"pmid": "21000429", "title": "The Rh factor.", "content": "The Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000429"}
{"pmid": "21000430", "title": "The rationale for the treatment of angina pectoris by irradiation of the adrenal glands.", "content": "The rationale for the treatment of angina pectoris by irradiation of the adrenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000430"}
{"pmid": "21000431", "title": "The treatment of angina pectoris by irradiation of the adrenal glands; clinical experience.", "content": "The treatment of angina pectoris by irradiation of the adrenal glands; clinical experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000431"}
{"pmid": "21000432", "title": "The effect of immunization on epidemic influenza.", "content": "The effect of immunization on epidemic influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000432"}
{"pmid": "21000433", "title": "Exfoliative dermatitis caused by sulfonamides and its reproduction by simple patch testing.", "content": "Exfoliative dermatitis caused by sulfonamides and its reproduction by simple patch testing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000433"}
{"pmid": "21000434", "title": "Meningococcemia with acute leptomeningitis and acute myocarditis.", "content": "Meningococcemia with acute leptomeningitis and acute myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000434"}
{"pmid": "21000435", "title": "Private hospitals have a right to exclude licensed physicians from use of the hospital.", "content": "Private hospitals have a right to exclude licensed physicians from use of the hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000435"}
{"pmid": "21000436", "title": "Hypoproteinaemia.", "content": "Hypoproteinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000436"}
{"pmid": "21000437", "title": "Fibrocystic disease of the pancreas.", "content": "Fibrocystic disease of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000437"}
{"pmid": "21000439", "title": "Infantilism of renal origin.", "content": "Infantilism of renal origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000439"}
{"pmid": "21000438", "title": "Fibrocystic disease of the pancreas.", "content": "Fibrocystic disease of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000438"}
{"pmid": "21000440", "title": "Influenzal meningitis.", "content": "Influenzal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000440"}
{"pmid": "21000441", "title": "Thymoma.", "content": "Thymoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000441"}
{"pmid": "21000442", "title": "Bronchiectasis involving all lobes of both lungs treated by lobectomy and multiple segmental resections.", "content": "Bronchiectasis involving all lobes of both lungs treated by lobectomy and multiple segmental resections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000442"}
{"pmid": "21000443", "title": "Multiple cysts of the right lung and the right bronchus.", "content": "Multiple cysts of the right lung and the right bronchus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000443"}
{"pmid": "21000444", "title": "Epileptiform attacks of sensations of taste and smell; unilateral Parkinsonian tremor (undiagnosed).", "content": "Epileptiform attacks of sensations of taste and smell; unilateral Parkinsonian tremor (undiagnosed).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000444"}
{"pmid": "21000445", "title": "Functional recovery following common peroneal nerve suture.", "content": "Functional recovery following common peroneal nerve suture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000445"}
{"pmid": "21000446", "title": "Disseminated sclerosis in one of uniovular twins, the other twin being similarly affected.", "content": "Disseminated sclerosis in one of uniovular twins, the other twin being similarly affected.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000446"}
{"pmid": "21000447", "title": "Symposium on the surgical treatment of myasthenia gravis.", "content": "Symposium on the surgical treatment of myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000447"}
{"pmid": "21000448", "title": "Notes on the pathology of the thymus glands removed in the surgical treatment of myasthenia gravis.", "content": "Notes on the pathology of the thymus glands removed in the surgical treatment of myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000448"}
{"pmid": "21000455", "title": "Discussion on dental structure and dental caries.", "content": "Discussion on dental structure and dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000455"}
{"pmid": "21000456", "title": "The structure of enamel and dentine from the chemical and physical aspect.", "content": "The structure of enamel and dentine from the chemical and physical aspect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000456"}
{"pmid": "21000463", "title": "British- Swiss Medical Conference, Basle, September 16-21, 1946.", "content": "British- Swiss Medical Conference, Basle, September 16-21, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000463"}
{"pmid": "21000464", "title": "Oestrogens in cancer.", "content": "Oestrogens in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000464"}
{"pmid": "21000465", "title": "Acoustic trauma; its origin and prevention.", "content": "Acoustic trauma; its origin and prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000465"}
{"pmid": "21000466", "title": "Circulatory failure.", "content": "Circulatory failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000466"}
{"pmid": "21000467", "title": "The physiology of the kidney in infancy and its importance in paediatrics.", "content": "The physiology of the kidney in infancy and its importance in paediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000467"}
{"pmid": "21000468", "title": "The differentiation of sympathicotropic drug action.", "content": "The differentiation of sympathicotropic drug action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000468"}
{"pmid": "21000469", "title": "Investigations on head injuries in Britain during the Second World War.", "content": "Investigations on head injuries in Britain during the Second World War.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000469"}
{"pmid": "21000470", "title": "High altitude in the treatment of tuberculosis.", "content": "High altitude in the treatment of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000470"}
{"pmid": "21000471", "title": "Amputations.", "content": "Amputations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000471"}
{"pmid": "21000472", "title": "Twenty years of research in typhus fever.", "content": "Twenty years of research in typhus fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000472"}
{"pmid": "21000473", "title": "Experimental radiotherapeutics.", "content": "Experimental radiotherapeutics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000473"}
{"pmid": "21000474", "title": "Nutrition in Switzerland during the war.", "content": "Nutrition in Switzerland during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000474"}
{"pmid": "21000475", "title": "Experimental diabetes mellitus.", "content": "Experimental diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000475"}
{"pmid": "21000477", "title": "Normal and defective fat absorption in man.", "content": "Normal and defective fat absorption in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000477"}
{"pmid": "21000476", "title": "The adaptation of the cell to effort, altitude and to pathological oxygen deficiency.", "content": "The adaptation of the cell to effort, altitude and to pathological oxygen deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000476"}
{"pmid": "21000478", "title": "Immediate and late results of carotid ligature in intracranial aneurysms.", "content": "Immediate and late results of carotid ligature in intracranial aneurysms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000478"}
{"pmid": "21000479", "title": "Primitive tuberculosis, primary infection and premunition.", "content": "Primitive tuberculosis, primary infection and premunition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000479"}
{"pmid": "21000480", "title": "Industrial medicine.", "content": "Industrial medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000480"}
{"pmid": "21000481", "title": "The Rh blood groups.", "content": "The Rh blood groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000481"}
{"pmid": "21000482", "title": "The chemotherapeutic control of malaria.", "content": "The chemotherapeutic control of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000482"}
{"pmid": "21000483", "title": "The regulation of the lung volume and its disturbances.", "content": "The regulation of the lung volume and its disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000483"}
{"pmid": "21000484", "title": "Arterial injuries.", "content": "Arterial injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000484"}
{"pmid": "21000485", "title": "Child life and health.", "content": "Child life and health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000485"}
{"pmid": "21000486", "title": "The heart's localizations of the thrombo-angiitis obliterans.", "content": "The heart's localizations of the thrombo-angiitis obliterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000486"}
{"pmid": "21000487", "title": "The University of Basle and its relations with England.", "content": "The University of Basle and its relations with England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000487"}
{"pmid": "21000490", "title": "Medical Faculty of Basle.", "content": "Medical Faculty of Basle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000490"}
{"pmid": "21000491", "title": "Medical education in Berne.", "content": "Medical education in Berne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000491"}
{"pmid": "21000492", "title": "Medical School of Geneva.", "content": "Medical School of Geneva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000492"}
{"pmid": "21000493", "title": "Zurich's relations with Britain.", "content": "Zurich's relations with Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000493"}
{"pmid": "21000501", "title": "A shorter psychotherapy.", "content": "A shorter psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000501"}
{"pmid": "21000502", "title": "Dicumarol; its use in acute coronary thrombosis.", "content": "Dicumarol; its use in acute coronary thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000502"}
{"pmid": "21000503", "title": "Enteric-coated medication ineffective.", "content": "Enteric-coated medication ineffective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000503"}
{"pmid": "21000504", "title": "Studies on infectious (epidemic) hepatitis and serum hepatitis.", "content": "Studies on infectious (epidemic) hepatitis and serum hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000504"}
{"pmid": "21000505", "title": "Recent studies in arsenical chemotherapy.", "content": "Recent studies in arsenical chemotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000505"}
{"pmid": "21000506", "title": "The cellular mechanism of recovery after treatment with penicillin.", "content": "The cellular mechanism of recovery after treatment with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000506"}
{"pmid": "21000507", "title": "Atomic energy and cancer.", "content": "Atomic energy and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000507"}
{"pmid": "21000508", "title": "Chronic osteomyelitis as depicted in a suit for a medical fee in Massachusetts in 1660.", "content": "Chronic osteomyelitis as depicted in a suit for a medical fee in Massachusetts in 1660.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000508"}
{"pmid": "21000509", "title": "A method of approach to psychosomatic problems in allergy.", "content": "A method of approach to psychosomatic problems in allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000509"}
{"pmid": "21000510", "title": "Medical care of veterans.", "content": "Medical care of veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000510"}
{"pmid": "21000511", "title": "Tuberculosis problems in West Virginia.", "content": "Tuberculosis problems in West Virginia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000511"}
{"pmid": "21000512", "title": "Care of the mentally ill at Weston State Hospital.", "content": "Care of the mentally ill at Weston State Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000512"}
{"pmid": "21000513", "title": "Congestive failure and cerebral accident.", "content": "Congestive failure and cerebral accident.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000513"}
{"pmid": "21000514", "title": "Some hematologic standards of women college students.", "content": "Some hematologic standards of women college students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000514"}
{"pmid": "21000515", "title": "Laboratory methods in the teaching of biology.", "content": "Laboratory methods in the teaching of biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000515"}
{"pmid": "21000516", "title": "Human biology as an approach to biological principles.", "content": "Human biology as an approach to biological principles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000516"}
{"pmid": "21000517", "title": "The use of visual aids in the teaching of biology.", "content": "The use of visual aids in the teaching of biology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000517"}
{"pmid": "21000518", "title": "The mosquitoes of Tennessee.", "content": "The mosquitoes of Tennessee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000518"}
{"pmid": "21000519", "title": "Integration in premedical and prenursing classes.", "content": "Integration in premedical and prenursing classes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000519"}
{"pmid": "21000520", "title": "The estimation of total alkaloids in rye-grass (Lolium perenne L.).", "content": "The estimation of total alkaloids in rye-grass (Lolium perenne L.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000520"}
{"pmid": "21000521", "title": "Studies on perloline perloline derivatives.", "content": "Studies on perloline perloline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000521"}
{"pmid": "21000522", "title": "Casein mucilage.", "content": "Casein mucilage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000522"}
{"pmid": "21000523", "title": "Biology of Anobium punctatum.", "content": "Biology of Anobium punctatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000523"}
{"pmid": "21000525", "title": "Stress analysis by photoelastic method; two-dimensional principles and practice.", "content": "Stress analysis by photoelastic method; two-dimensional principles and practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000525"}
{"pmid": "21000524", "title": "A metal thermoregulator.", "content": "A metal thermoregulator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000524"}
{"pmid": "21000526", "title": "Rot-proofing of canvas; preliminary report on experiments carried out in 1944-45.", "content": "Rot-proofing of canvas; preliminary report on experiments carried out in 1944-45.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000526"}
{"pmid": "21000527", "title": "Radon micro determination by the Curtiss-Davis particle counting method.", "content": "Radon micro determination by the Curtiss-Davis particle counting method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000527"}
{"pmid": "21000528", "title": "A useful laboratory vacuum-tube volt-meter.", "content": "A useful laboratory vacuum-tube volt-meter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000528"}
{"pmid": "21000530", "title": "Note on Bironella (Brugella) hollandi Taylor.", "content": "Note on Bironella (Brugella) hollandi Taylor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000530"}
{"pmid": "21000529", "title": "Studies on perloline; perlolidine and some fluorescent derivatives of perloline.", "content": "Studies on perloline; perlolidine and some fluorescent derivatives of perloline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000529"}
{"pmid": "21000531", "title": "An alpha-ray ionisation chamber for radioactivity measurements.", "content": "An alpha-ray ionisation chamber for radioactivity measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000531"}
{"pmid": "21000532", "title": "The transuranium elements.", "content": "The transuranium elements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000532"}
{"pmid": "21000533", "title": "Unequal distribution of diffusible nonelectrolytes across a membrane.", "content": "Unequal distribution of diffusible nonelectrolytes across a membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000533"}
{"pmid": "21000534", "title": "The use of cytochrome C in combating tissue anoxia.", "content": "The use of cytochrome C in combating tissue anoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000534"}
{"pmid": "21000535", "title": "An improved helmet for breathing oxygen or other gases.", "content": "An improved helmet for breathing oxygen or other gases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000535"}
{"pmid": "21000536", "title": "Reciprocal sensitivities of Staphylococcus aureus to streptomycin, streptothricin, and penicillin.", "content": "Reciprocal sensitivities of Staphylococcus aureus to streptomycin, streptothricin, and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000536"}
{"pmid": "21000537", "title": "Surface measurements of radioactive phosphorus in breast tumors as a possible diagnostic method.", "content": "Surface measurements of radioactive phosphorus in breast tumors as a possible diagnostic method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000537"}
{"pmid": "21000538", "title": "Correction on the nomenclature of human Plasmodium.", "content": "Correction on the nomenclature of human Plasmodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000538"}
{"pmid": "21000539", "title": "Radioactive hydrocarbons.", "content": "Radioactive hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000539"}
{"pmid": "21000540", "title": "Aging of tissues; the necessity for research.", "content": "Aging of tissues; the necessity for research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000540"}
{"pmid": "21000541", "title": "Studies of vitamin deficiency.", "content": "Studies of vitamin deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000541"}
{"pmid": "21000542", "title": "Distribution of sodium and water in muscle following severe cold injury.", "content": "Distribution of sodium and water in muscle following severe cold injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000542"}
{"pmid": "21000544", "title": "Grafts of free muscle transplants upon the myocardium.", "content": "Grafts of free muscle transplants upon the myocardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000544"}
{"pmid": "21000543", "title": "Mechanism of hyaluronidase action in skin.", "content": "Mechanism of hyaluronidase action in skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000543"}
{"pmid": "21000545", "title": "Effect of penicillin on seed germination.", "content": "Effect of penicillin on seed germination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000545"}
{"pmid": "21000546", "title": "A new Helminthosporium blight of oats.", "content": "A new Helminthosporium blight of oats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000546"}
{"pmid": "21000547", "title": "Maintenance of penicillin blood levels after a single intramuscular injection of penicillin in various oils.", "content": "Maintenance of penicillin blood levels after a single intramuscular injection of penicillin in various oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000547"}
{"pmid": "21000548", "title": "The chloride content of conifers.", "content": "The chloride content of conifers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000548"}
{"pmid": "21000549", "title": "Bone marrow of horses and cattle.", "content": "Bone marrow of horses and cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000549"}
{"pmid": "21000550", "title": "Fine-tapered silver electrodes for physiological work.", "content": "Fine-tapered silver electrodes for physiological work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000550"}
{"pmid": "21000551", "title": "Use of sulfuric acid-dichromate mixture in cleaning glassware.", "content": "Use of sulfuric acid-dichromate mixture in cleaning glassware.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000551"}
{"pmid": "21000552", "title": "The effect of urethane on lymphatic leukemia in rats.", "content": "The effect of urethane on lymphatic leukemia in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000552"}
{"pmid": "21000553", "title": "A nutritional concept of cancer.", "content": "A nutritional concept of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000553"}
{"pmid": "21000554", "title": "On methods of food appraisal.", "content": "On methods of food appraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000554"}
{"pmid": "21000555", "title": "The distribution of the pathologic lesions of the central nervous system in scrub typhus (tsutsugamushi disease).", "content": "The distribution of the pathologic lesions of the central nervous system in scrub typhus (tsutsugamushi disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000555"}
{"pmid": "21000556", "title": "Morphologic changes in the brain of monkeys following convulsions electrically induced.", "content": "Morphologic changes in the brain of monkeys following convulsions electrically induced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000556"}
{"pmid": "21000557", "title": "Spina bifida and the cerebrospinal fluid.", "content": "Spina bifida and the cerebrospinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000557"}
{"pmid": "21000558", "title": "Syphilitic amyotrophy; clinical-pathological report of a case complicating tabes dorsalis.", "content": "Syphilitic amyotrophy; clinical-pathological report of a case complicating tabes dorsalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000558"}
{"pmid": "21000559", "title": "Experimental arteriosclerosis in the nervous system.", "content": "Experimental arteriosclerosis in the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000559"}
{"pmid": "21000560", "title": "Atresia and stenosis of the aqueduct of Sylvius.", "content": "Atresia and stenosis of the aqueduct of Sylvius.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000560"}
{"pmid": "21000561", "title": "Acetylcholine induced depression of cerebral cortical activity.", "content": "Acetylcholine induced depression of cerebral cortical activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000561"}
{"pmid": "21000562", "title": "The pyramidal tract; the relation of axonal diameters to the rate of degeneration as revealed by the acid phosphatase method in the monkey.", "content": "The pyramidal tract; the relation of axonal diameters to the rate of degeneration as revealed by the acid phosphatase method in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000562"}
{"pmid": "21000606", "title": "Masochism in paranoia.", "content": "Masochism in paranoia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000606"}
{"pmid": "21000607", "title": "Psychoanalytic study of ulcerative colitis in children.", "content": "Psychoanalytic study of ulcerative colitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000607"}
{"pmid": "21000608", "title": "A case of sterility.", "content": "A case of sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000608"}
{"pmid": "21000609", "title": "A depression which recurred annually.", "content": "A depression which recurred annually.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000609"}
{"pmid": "21000610", "title": "A study of lewisite lesions of the eyes of rabbits.", "content": "A study of lewisite lesions of the eyes of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000610"}
{"pmid": "21000611", "title": "Macular edema.", "content": "Macular edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000611"}
{"pmid": "21000612", "title": "The relation between maternal vitamin-A intake, blood level, and ocular abnormalities in the offspring of the rat.", "content": "The relation between maternal vitamin-A intake, blood level, and ocular abnormalities in the offspring of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000612"}
{"pmid": "21000613", "title": "Intraocular manifestations on acute disseminated lupus erythematosus.", "content": "Intraocular manifestations on acute disseminated lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000613"}
{"pmid": "21000614", "title": "Nutritional amblyopia in American prisoners of war liberated from the Japanese.", "content": "Nutritional amblyopia in American prisoners of war liberated from the Japanese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000614"}
{"pmid": "21000615", "title": "Changes in the angioscotomas associated with the oral administration of evipal.", "content": "Changes in the angioscotomas associated with the oral administration of evipal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000615"}
{"pmid": "21000616", "title": "The role of lens substance in experimental gonorrheal iritis.", "content": "The role of lens substance in experimental gonorrheal iritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000616"}
{"pmid": "21000617", "title": "Spontaneous rupture of the lens capsule in anterior lenticonus.", "content": "Spontaneous rupture of the lens capsule in anterior lenticonus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000617"}
{"pmid": "21000618", "title": "Contusion cataract of the anterior lens capsule.", "content": "Contusion cataract of the anterior lens capsule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000618"}
{"pmid": "21000619", "title": "A statistical review of 367 blinded service men, World War II.", "content": "A statistical review of 367 blinded service men, World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000619"}
{"pmid": "21000620", "title": "Operative procedure for subluxated lens.", "content": "Operative procedure for subluxated lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000620"}
{"pmid": "21000621", "title": "Unusual complication of sphenopalatine block.", "content": "Unusual complication of sphenopalatine block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000621"}
{"pmid": "21000622", "title": "Recurrent detachment of the choroid following trephining operation.", "content": "Recurrent detachment of the choroid following trephining operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000622"}
{"pmid": "21000623", "title": "Neurofibromatosis in three consecutive generations.", "content": "Neurofibromatosis in three consecutive generations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000623"}
{"pmid": "21000624", "title": "A possible early case of ocular pemphigus.", "content": "A possible early case of ocular pemphigus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000624"}
{"pmid": "21000625", "title": "Herpes zoster ophthalmicus appearing after trauma.", "content": "Herpes zoster ophthalmicus appearing after trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000625"}
{"pmid": "21000626", "title": "Surgical methods of treating paralysis of the superior oblique muscle.", "content": "Surgical methods of treating paralysis of the superior oblique muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000626"}
{"pmid": "21000627", "title": "Choroiditis treated by penicillin.", "content": "Choroiditis treated by penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000627"}
{"pmid": "21000628", "title": "Retinal detachment, multiple operations, posterior sclerotomy.", "content": "Retinal detachment, multiple operations, posterior sclerotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000628"}
{"pmid": "21000629", "title": "Microphthalmos, harelip, and cleft palate.", "content": "Microphthalmos, harelip, and cleft palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000629"}
{"pmid": "21000630", "title": "Malignant melanoma of iris and ciliary body.", "content": "Malignant melanoma of iris and ciliary body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000630"}
{"pmid": "21000631", "title": "Clinical aspects and treatment of exophthalmos from the experimental viewpoint.", "content": "Clinical aspects and treatment of exophthalmos from the experimental viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000631"}
{"pmid": "21000632", "title": "Wetting agents and detergents.", "content": "Wetting agents and detergents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000632"}
{"pmid": "21000633", "title": "The technique of fitting scleraform contact lenses; determination of the shape of the human eye by insertion of spherical contact lenses.", "content": "The technique of fitting scleraform contact lenses; determination of the shape of the human eye by insertion of spherical contact lenses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000633"}
{"pmid": "21000634", "title": "Modern visual development.", "content": "Modern visual development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000634"}
{"pmid": "21000635", "title": "Physical aspects of aniseikonia.", "content": "Physical aspects of aniseikonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000635"}
{"pmid": "21000636", "title": "The technique of fitting scleraform contact lenses; measurement of the scleral radii of the eye and duplication thereof on the scleral section of the contact lens.", "content": "The technique of fitting scleraform contact lenses; measurement of the scleral radii of the eye and duplication thereof on the scleral section of the contact lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000636"}
{"pmid": "21000641", "title": "Recent developments in the knowledge of the Rh-Hr blood types; tests for Rh sensitization.", "content": "Recent developments in the knowledge of the Rh-Hr blood types; tests for Rh sensitization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000641"}
{"pmid": "21000642", "title": "The Rh factor as applied to the operation of blood banks.", "content": "The Rh factor as applied to the operation of blood banks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000642"}
{"pmid": "21000644", "title": "A physiologic study of hematopoiesis in the duck with malaria.", "content": "A physiologic study of hematopoiesis in the duck with malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000644"}
{"pmid": "21000643", "title": "Alloxan in experimental hemochromatosis.", "content": "Alloxan in experimental hemochromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000643"}
{"pmid": "21000645", "title": "Development of resistance to streptomycin by Aerobacter cloacae.", "content": "Development of resistance to streptomycin by Aerobacter cloacae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000645"}
{"pmid": "21000646", "title": "Absorption of vitamin A following enteral use of prostigmine in cystic fibrosis of pancreas.", "content": "Absorption of vitamin A following enteral use of prostigmine in cystic fibrosis of pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000646"}
{"pmid": "21000637", "title": "OTOLOGIST'S role in the fitting of hearing aids.", "content": "OTOLOGIST'S role in the fitting of hearing aids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000637"}
{"pmid": "21000647", "title": "Observations on response of macrocytic anemias to folic acid therapy.", "content": "Observations on response of macrocytic anemias to folic acid therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000647"}
{"pmid": "21000639", "title": "Eye conservation and increased production.", "content": "Eye conservation and increased production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000639"}
{"pmid": "21000648", "title": "Malignant lymphoma; analysis of 202 cases.", "content": "Malignant lymphoma; analysis of 202 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000648"}
{"pmid": "21000638", "title": "How ophthalmic eye-care can prevent many industrial accidents.", "content": "How ophthalmic eye-care can prevent many industrial accidents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000638"}
{"pmid": "21000650", "title": "Observations on human malnutrition.", "content": "Observations on human malnutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000650"}
{"pmid": "21000649", "title": "Rh incompatibility in heterospecific pregnancy.", "content": "Rh incompatibility in heterospecific pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000649"}
{"pmid": "21000640", "title": "Ocular effects of radiant energy.", "content": "Ocular effects of radiant energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000640"}
{"pmid": "21000651", "title": "Radiation effects of the atomic bomb among the natives of Nagasaki, Kyushu.", "content": "Radiation effects of the atomic bomb among the natives of Nagasaki, Kyushu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000651"}
{"pmid": "21000652", "title": "A simple flocculation slide test for the diagnosis of schistosomiasis.", "content": "A simple flocculation slide test for the diagnosis of schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000652"}
{"pmid": "21000654", "title": "Microscopic examination of urinary calculi.", "content": "Microscopic examination of urinary calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000654"}
{"pmid": "21000653", "title": "Photoelectric determination of sulfonamides in blood filtrates.", "content": "Photoelectric determination of sulfonamides in blood filtrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000653"}
{"pmid": "21000655", "title": "A rapid system for routine urine analysis.", "content": "A rapid system for routine urine analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000655"}
{"pmid": "21000656", "title": "Single sample of blood for multiple tests.", "content": "Single sample of blood for multiple tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000656"}
{"pmid": "21000657", "title": "Vacutainer for collection of citrated blood; with a note on determination of presumptive sedimentation rates.", "content": "Vacutainer for collection of citrated blood; with a note on determination of presumptive sedimentation rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000657"}
{"pmid": "21000659", "title": "Trends in modern medicinals.", "content": "Trends in modern medicinals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000659"}
{"pmid": "21000658", "title": "Vacutainer for collection of citrated blood in tests for syphilis; recalcification of plasma by gypsum; inactivation of serum with clots.", "content": "Vacutainer for collection of citrated blood in tests for syphilis; recalcification of plasma by gypsum; inactivation of serum with clots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000658"}
{"pmid": "21000660", "title": "The synergistic action of detergents and sulfaguanidine and succinylsulfathiazole.", "content": "The synergistic action of detergents and sulfaguanidine and succinylsulfathiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000660"}
{"pmid": "21000661", "title": "The uses and limitations of de-ionized water for pharmaceutical purposes.", "content": "The uses and limitations of de-ionized water for pharmaceutical purposes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000661"}
{"pmid": "21000662", "title": "SITUATION in Switzerland with regard to pharmaceutical specialties.", "content": "SITUATION in Switzerland with regard to pharmaceutical specialties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000662"}
{"pmid": "21000663", "title": "The effect of acetone on the surface tension and the bactericidal efficiency of aerosol OT.", "content": "The effect of acetone on the surface tension and the bactericidal efficiency of aerosol OT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000663"}
{"pmid": "21000664", "title": "Medical problems of today.", "content": "Medical problems of today.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000664"}
{"pmid": "21000665", "title": "Mechanism vs. vitalism.", "content": "Mechanism vs. vitalism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000665"}
{"pmid": "21000666", "title": "Nucleonics pharmacology.", "content": "Nucleonics pharmacology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000666"}
{"pmid": "21000667", "title": "HEALTH insurance on a voluntary basis.", "content": "HEALTH insurance on a voluntary basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000667"}
{"pmid": "21000668", "title": "Orris root, its oil and its resinoid.", "content": "Orris root, its oil and its resinoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000668"}
{"pmid": "21000669", "title": "Atomic energy in medicine.", "content": "Atomic energy in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000669"}
{"pmid": "21000670", "title": "[Basic problems in the Soviet search for new medicinals].", "content": "[Basic problems in the Soviet search for new medicinals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000670"}
{"pmid": "21000671", "title": "[Chemico-pharmaceutical industry in the war- and postwar-period].", "content": "[Chemico-pharmaceutical industry in the war- and postwar-period].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000671"}
{"pmid": "21000672", "title": "[Pharmacotherapy].", "content": "[Pharmacotherapy].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000672"}
{"pmid": "21000673", "title": "[The search for biologically active substances].", "content": "[The search for biologically active substances].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000673"}
{"pmid": "21000674", "title": "[Some results of experimental anti-endotoxin chemotherapy].", "content": "[Some results of experimental anti-endotoxin chemotherapy].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000674"}
{"pmid": "21000675", "title": "[Search for new medicinals in USSR].", "content": "[Search for new medicinals in USSR].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000675"}
{"pmid": "21000676", "title": "[Detoxication of snake venom with thiosulfate sodium].", "content": "[Detoxication of snake venom with thiosulfate sodium].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000676"}
{"pmid": "21000677", "title": "[Evaluation of preparations of medical charcoal in the supply of the German Army].", "content": "[Evaluation of preparations of medical charcoal in the supply of the German Army].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000677"}
{"pmid": "21000678", "title": "[Desensitizing action of some medicinal remedies] [pyramidon, antipyrin and salicylate in asthma].", "content": "[Desensitizing action of some medicinal remedies] [pyramidon, antipyrin and salicylate in asthma].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000678"}
{"pmid": "21000680", "title": "[Toxicity of fir oil].", "content": "[Toxicity of fir oil].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000680"}
{"pmid": "21000679", "title": "[Pharmacology of 4-azophenyl-sulfanilamido-o-butylphenol].", "content": "[Pharmacology of 4-azophenyl-sulfanilamido-o-butylphenol].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000679"}
{"pmid": "21000681", "title": "[Analysis of the mechanism of histamine intoxication at various age levels].", "content": "[Analysis of the mechanism of histamine intoxication at various age levels].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000681"}
{"pmid": "21000682", "title": "[Adrenaline shock and the mechanism of adrenaline bradycardia in the young; experiments on dogs and rabbits].", "content": "[Adrenaline shock and the mechanism of adrenaline bradycardia in the young; experiments on dogs and rabbits].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000682"}
{"pmid": "21000683", "title": "[Types of reactions of animals to adrenaline].", "content": "[Types of reactions of animals to adrenaline].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000683"}
{"pmid": "21000684", "title": "[The effect of caffeine on the secretory reactions of the intestines].", "content": "[The effect of caffeine on the secretory reactions of the intestines].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000684"}
{"pmid": "21000685", "title": "[Spasm of sphincter muscles provoked by morphine].", "content": "[Spasm of sphincter muscles provoked by morphine].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000685"}
{"pmid": "21000686", "title": "[Local anesthetizing properties of diethylamino butylinic ether of p-aminobenzoic acid].", "content": "[Local anesthetizing properties of diethylamino butylinic ether of p-aminobenzoic acid].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000686"}
{"pmid": "21000687", "title": "[Use of drugs affecting the liver function].", "content": "[Use of drugs affecting the liver function].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000687"}
{"pmid": "21000688", "title": "[Siberian plants; a substitute for Strophanthus] [Erysimum].", "content": "[Siberian plants; a substitute for Strophanthus] [Erysimum].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000688"}
{"pmid": "21000689", "title": "[Action of Thermopsis dolichocarpa in comparison with Thermopsis lanceolata].", "content": "[Action of Thermopsis dolichocarpa in comparison with Thermopsis lanceolata].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000689"}
{"pmid": "21000690", "title": "[Effect of benzol and benzene on the organism under reduced barometric pressure].", "content": "[Effect of benzol and benzene on the organism under reduced barometric pressure].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000690"}
{"pmid": "21000691", "title": "[Poisoning with glyzantine and antifreeze].", "content": "[Poisoning with glyzantine and antifreeze].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000691"}
{"pmid": "21000692", "title": "[Toxicology of bromethyl].", "content": "[Toxicology of bromethyl].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000692"}
{"pmid": "21000693", "title": "[Use of local raw materials in the manufacture of medical supplies for wide distribution].", "content": "[Use of local raw materials in the manufacture of medical supplies for wide distribution].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000693"}
{"pmid": "21000694", "title": "[Pharmacal economics].", "content": "[Pharmacal economics].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000694"}
{"pmid": "21000695", "title": "[Medical supplies must be better serviced].", "content": "[Medical supplies must be better serviced].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000695"}
{"pmid": "21000696", "title": "[New trends in production of pharmaceutical preparations from vegetable raw materials].", "content": "[New trends in production of pharmaceutical preparations from vegetable raw materials].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000696"}
{"pmid": "21000697", "title": "[Qualitative determination of atophan and cinchonine].", "content": "[Qualitative determination of atophan and cinchonine].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000697"}
{"pmid": "21000698", "title": "[Phytosterine base for ointments].", "content": "[Phytosterine base for ointments].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000698"}
{"pmid": "21000699", "title": "[Calorimetric determination of small quantities of radix ipecacauanhae].", "content": "[Calorimetric determination of small quantities of radix ipecacauanhae].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000699"}
{"pmid": "21000700", "title": "[Dry concentrates of medical pastes].", "content": "[Dry concentrates of medical pastes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000700"}
{"pmid": "21000701", "title": "[Wound closing preparation from the leaves of Plantago major L.].", "content": "[Wound closing preparation from the leaves of Plantago major L.].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000701"}
{"pmid": "21000702", "title": "[White and yellow waterlilies].", "content": "[White and yellow waterlilies].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000702"}
{"pmid": "21000704", "title": "[Bistalbin, a new astringent protein preparation].", "content": "[Bistalbin, a new astringent protein preparation].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000704"}
{"pmid": "21000705", "title": "[Method of obtaining good distilled water].", "content": "[Method of obtaining good distilled water].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000705"}
{"pmid": "21000703", "title": "[Third All-Union Vitamin Conference].", "content": "[Third All-Union Vitamin Conference].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000703"}
{"pmid": "21000706", "title": "[Nomenclature of drugs].", "content": "[Nomenclature of drugs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000706"}
{"pmid": "21000717", "title": "Palmar skin resistance as a measure of physical fitness.", "content": "Palmar skin resistance as a measure of physical fitness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000717"}
{"pmid": "21000718", "title": "Studies on the nutritive value of lactose and galactose with the single-food choice method.", "content": "Studies on the nutritive value of lactose and galactose with the single-food choice method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000718"}
{"pmid": "21000719", "title": "Relation of gas tension and hydrostatic pressure to intravascular bubble formation.", "content": "Relation of gas tension and hydrostatic pressure to intravascular bubble formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000719"}
{"pmid": "21000720", "title": "The oxygen consumption and mechanical efficiency of the heart before and during heart failure.", "content": "The oxygen consumption and mechanical efficiency of the heart before and during heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000720"}
{"pmid": "21000721", "title": "Absence of rapid deterioration in moderately active young men on a restricted intake of B-complex vitamins and animal protein.", "content": "Absence of rapid deterioration in moderately active young men on a restricted intake of B-complex vitamins and animal protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000721"}
{"pmid": "21000722", "title": "The distribution of water and fat in the skin and muscle of the dog during chronic and acute dehydration.", "content": "The distribution of water and fat in the skin and muscle of the dog during chronic and acute dehydration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000722"}
{"pmid": "21000723", "title": "Arterial oxygen pressure during pure O2 breathing.", "content": "Arterial oxygen pressure during pure O2 breathing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000723"}
{"pmid": "21000724", "title": "Biochemical changes in the blood of rats after reapplication of limb tourniquets.", "content": "Biochemical changes in the blood of rats after reapplication of limb tourniquets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000724"}
{"pmid": "21000725", "title": "Evidence that the major portion of the gastric potential originates between the submucosa and mucosa.", "content": "Evidence that the major portion of the gastric potential originates between the submucosa and mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000725"}
{"pmid": "21000707", "title": "The possibility of using pigeons in toxicity determinations of organic antimony compounds.", "content": "The possibility of using pigeons in toxicity determinations of organic antimony compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000707"}
{"pmid": "21000726", "title": "A comparative study of the effects of oxygen lack on peripheral nerve.", "content": "A comparative study of the effects of oxygen lack on peripheral nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000726"}
{"pmid": "21000713", "title": "The significance of stomatal index as a differential character; studies in the genera Atropa, Datura, Digitalis, Phytolacca and in polyploid leaves.", "content": "The significance of stomatal index as a differential character; studies in the genera Atropa, Datura, Digitalis, Phytolacca and in polyploid leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000713"}
{"pmid": "21000708", "title": "Whole blood or other clotting systems in assaying heparin.", "content": "Whole blood or other clotting systems in assaying heparin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000708"}
{"pmid": "21000710", "title": "The design and statistical analysis of microbiological assays.", "content": "The design and statistical analysis of microbiological assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000710"}
{"pmid": "21000711", "title": "A polarographic study of alkaloids.", "content": "A polarographic study of alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000711"}
{"pmid": "21000709", "title": "The pharmacological assessment of antibacterial creams.", "content": "The pharmacological assessment of antibacterial creams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000709"}
{"pmid": "21000727", "title": "Excitation and inhibition of phrenic motoneurones by inflation of the lungs.", "content": "Excitation and inhibition of phrenic motoneurones by inflation of the lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000727"}
{"pmid": "21000729", "title": "The metabolic reduction and nephrotoxic action of tetrathionate in relation to a possible interaction with sulfhydryl compounds.", "content": "The metabolic reduction and nephrotoxic action of tetrathionate in relation to a possible interaction with sulfhydryl compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000729"}
{"pmid": "21000715", "title": "The assay of crystalline preparations of aneurine by means of the ultra-violet absorption spectrum.", "content": "The assay of crystalline preparations of aneurine by means of the ultra-violet absorption spectrum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000715"}
{"pmid": "21000728", "title": "A unitary analysis of pulmonary volume receptors.", "content": "A unitary analysis of pulmonary volume receptors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000728"}
{"pmid": "21000712", "title": "A note on khellinin as a coronary dilator.", "content": "A note on khellinin as a coronary dilator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000712"}
{"pmid": "21000716", "title": "Investigations on the autoxidation of diethyl ether; the pharmaceutical problems of ether.", "content": "Investigations on the autoxidation of diethyl ether; the pharmaceutical problems of ether.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000716"}
{"pmid": "21000714", "title": "The palisade ratio values of Atropa belladonna and Atropa acuminata.", "content": "The palisade ratio values of Atropa belladonna and Atropa acuminata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000714"}
{"pmid": "21000730", "title": "Electrical manifestations of the cerebellum and cerebral cortex following DDT administration in cats and monkeys.", "content": "Electrical manifestations of the cerebellum and cerebral cortex following DDT administration in cats and monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000730"}
{"pmid": "21000731", "title": "Bicarbonate and the renal regulation of acid base balance.", "content": "Bicarbonate and the renal regulation of acid base balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000731"}
{"pmid": "21000732", "title": "The standardization of hemorrhagic shock in the rat; observations on the effects of transfusions of whole blood and some blood substitutes.", "content": "The standardization of hemorrhagic shock in the rat; observations on the effects of transfusions of whole blood and some blood substitutes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000732"}
{"pmid": "21000733", "title": "Urea synthesis from amino acids during hemorrhagic shock in the nephrectomized rat.", "content": "Urea synthesis from amino acids during hemorrhagic shock in the nephrectomized rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000733"}
{"pmid": "21000734", "title": "Amino nitrogen in liver and muscle of rats in shock after hemorrhage.", "content": "Amino nitrogen in liver and muscle of rats in shock after hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000734"}
{"pmid": "21000735", "title": "The influence of feeding on the effects of hepatic anoxia on the respiration of liver slices in vitro.", "content": "The influence of feeding on the effects of hepatic anoxia on the respiration of liver slices in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000735"}
{"pmid": "21000736", "title": "On the determination of the physiologically effective pressures of oxygen and carbon dioxide in alveolar air.", "content": "On the determination of the physiologically effective pressures of oxygen and carbon dioxide in alveolar air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000736"}
{"pmid": "21000737", "title": "An experimental analysis in man of the oxygen pressure gradient from alveolar air to arterial blood during rest and exercise at sea level and at altitude.", "content": "An experimental analysis in man of the oxygen pressure gradient from alveolar air to arterial blood during rest and exercise at sea level and at altitude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000737"}
{"pmid": "21000739", "title": "The effect of adrenalectomy in rats on urinary non-protein nitrogen during forced-feeding and during fasting.", "content": "The effect of adrenalectomy in rats on urinary non-protein nitrogen during forced-feeding and during fasting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000739"}
{"pmid": "21000738", "title": "Carbon dioxide production of humans at sea level and at low barometric pressures.", "content": "Carbon dioxide production of humans at sea level and at low barometric pressures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000738"}
{"pmid": "21000740", "title": "The effect of fasting upon the tolerance of normal rats to a high carbohydrate diet administered by stomach tube.", "content": "The effect of fasting upon the tolerance of normal rats to a high carbohydrate diet administered by stomach tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000740"}
{"pmid": "21000741", "title": "The influence of thiamine on the action of acetylcholine on muscle.", "content": "The influence of thiamine on the action of acetylcholine on muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000741"}
{"pmid": "21000742", "title": "The permeability of blood capillary sprouts and newly formed blood capillaries as compared to that of older blood capillaries.", "content": "The permeability of blood capillary sprouts and newly formed blood capillaries as compared to that of older blood capillaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000742"}
{"pmid": "21000743", "title": "The nature of intraperitoneal and intrarectal pressures.", "content": "The nature of intraperitoneal and intrarectal pressures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000743"}
{"pmid": "21000744", "title": "Desensitization of mice to placental toxin.", "content": "Desensitization of mice to placental toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000744"}
{"pmid": "21000745", "title": "Placental toxin; inactivation and tolerance during pregnancy.", "content": "Placental toxin; inactivation and tolerance during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000745"}
{"pmid": "21000746", "title": "Changes in arterial and venous blood pressure and flow distal to a cuff inflated on the human arm.", "content": "Changes in arterial and venous blood pressure and flow distal to a cuff inflated on the human arm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000746"}
{"pmid": "21000747", "title": "Studies of right and left ventricular activity during hemorrhagic hypotension and shock.", "content": "Studies of right and left ventricular activity during hemorrhagic hypotension and shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000747"}
{"pmid": "21000748", "title": "Studies on the biological effect of high frequency radio waves (radar).", "content": "Studies on the biological effect of high frequency radio waves (radar).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000748"}
{"pmid": "21000749", "title": "The effect of time of day on the metabolic rate of albino mice; a manometric method.", "content": "The effect of time of day on the metabolic rate of albino mice; a manometric method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000749"}
{"pmid": "21000750", "title": "The general tolerance and cardiovascular responses of animals to explosive decompression.", "content": "The general tolerance and cardiovascular responses of animals to explosive decompression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000750"}
{"pmid": "21000751", "title": "The assay of nephrosclerosis producing anterior pituitary preparations.", "content": "The assay of nephrosclerosis producing anterior pituitary preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000751"}
{"pmid": "21000753", "title": "A study on the pathway from the medial geniculate body to the acoustic cortex in the dog.", "content": "A study on the pathway from the medial geniculate body to the acoustic cortex in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000753"}
{"pmid": "21000752", "title": "Movements of body water in response to acute blood loss.", "content": "Movements of body water in response to acute blood loss.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000752"}
{"pmid": "21000754", "title": "The relation of temperature and the thyroid to mammalian reproductive physiology.", "content": "The relation of temperature and the thyroid to mammalian reproductive physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000754"}
{"pmid": "21000755", "title": "Hemodynamics in pulmonary irritant poisoning.", "content": "Hemodynamics in pulmonary irritant poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000755"}
{"pmid": "21000756", "title": "Sodium chloride as an adjunct to a diet of whole wheat and whole milk.", "content": "Sodium chloride as an adjunct to a diet of whole wheat and whole milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000756"}
{"pmid": "21000757", "title": "Effect of pentothal anesthesia on canine cerebral cortex.", "content": "Effect of pentothal anesthesia on canine cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000757"}
{"pmid": "21000758", "title": "Lipotropic action of lipocaic; a study of the effect of oral and parenteral lipocaic and oral inositol on the dietary fatty liver of the white rat.", "content": "Lipotropic action of lipocaic; a study of the effect of oral and parenteral lipocaic and oral inositol on the dietary fatty liver of the white rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000758"}
{"pmid": "21000759", "title": "Formulation of the principal factors affecting the rate of uptake of carbon monoxide by man.", "content": "Formulation of the principal factors affecting the rate of uptake of carbon monoxide by man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000759"}
{"pmid": "21000760", "title": "Permeability of the placenta of the guinea pig to inorganic phosphate and its relation to fetal growth.", "content": "Permeability of the placenta of the guinea pig to inorganic phosphate and its relation to fetal growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000760"}
{"pmid": "21000762", "title": "The effect of necrosin on the blood sugar level.", "content": "The effect of necrosin on the blood sugar level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000762"}
{"pmid": "21000761", "title": "Decline in the rates of sweating of men working in severe heat.", "content": "Decline in the rates of sweating of men working in severe heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000761"}
{"pmid": "21000763", "title": "Apparent curare effect of substances that decrease acetylcholine synthesis.", "content": "Apparent curare effect of substances that decrease acetylcholine synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000763"}
{"pmid": "21000764", "title": "Sweat gland activity and changing patterns of sweat secretion on the skin surface.", "content": "Sweat gland activity and changing patterns of sweat secretion on the skin surface.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000764"}
{"pmid": "21000765", "title": "Water and salt exchange during chronic and acute dehydration in the dog.", "content": "Water and salt exchange during chronic and acute dehydration in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000765"}
{"pmid": "21000766", "title": "Hyperchromic anemia produced by choline or acetyl choline and the induced remission of both by folic acid or liver injection; the probable mechanism of action of liver and folic acid in treatment of anemia.", "content": "Hyperchromic anemia produced by choline or acetyl choline and the induced remission of both by folic acid or liver injection; the probable mechanism of action of liver and folic acid in treatment of anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000766"}
{"pmid": "21000767", "title": "The recovery of injected dye and the yield of blood cells by perfusion of the cardiovascular system in barbitalized dogs.", "content": "The recovery of injected dye and the yield of blood cells by perfusion of the cardiovascular system in barbitalized dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000767"}
{"pmid": "21000768", "title": "The influence of caloric restriction of plasma protein, hemoglobin and hematocrit values in the rat.", "content": "The influence of caloric restriction of plasma protein, hemoglobin and hematocrit values in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000768"}
{"pmid": "21000769", "title": "The effect of methyl xanthines on the formation of urea in rabbits.", "content": "The effect of methyl xanthines on the formation of urea in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000769"}
{"pmid": "21000770", "title": "The role of secondary reinforcement in a partial reinforcement learning situation.", "content": "The role of secondary reinforcement in a partial reinforcement learning situation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000770"}
{"pmid": "21000771", "title": "Dark adaptation as a factor in the sensitization of the beta response of the eyelid to light.", "content": "Dark adaptation as a factor in the sensitization of the beta response of the eyelid to light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000771"}
{"pmid": "21000772", "title": "Level of aspiration; ambition or defense?", "content": "Level of aspiration; ambition or defense?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000772"}
{"pmid": "21000773", "title": "The effect of context upon judgments of pitch differences.", "content": "The effect of context upon judgments of pitch differences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000773"}
{"pmid": "21000774", "title": "Development of speech during infancy; curve of phonemic types.", "content": "Development of speech during infancy; curve of phonemic types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000774"}
{"pmid": "21000775", "title": "Adaptation in energy mobilization: changes in general level of palmar skin conductance.", "content": "Adaptation in energy mobilization: changes in general level of palmar skin conductance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000775"}
{"pmid": "21000776", "title": "Validity of frequency of blinking as a criterion of readability.", "content": "Validity of frequency of blinking as a criterion of readability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000776"}
{"pmid": "21000777", "title": "The effects of certain pre-training procedures upon maze performance and their significance for the concept of latent learning.", "content": "The effects of certain pre-training procedures upon maze performance and their significance for the concept of latent learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000777"}
{"pmid": "21000778", "title": "Mental hygiene in the atomic age.", "content": "Mental hygiene in the atomic age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000778"}
{"pmid": "21000779", "title": "Women and modern stress.", "content": "Women and modern stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000779"}
{"pmid": "21000780", "title": "Group psychotherapy with veterans.", "content": "Group psychotherapy with veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000780"}
{"pmid": "21000781", "title": "Lessons from military psychiatry for civilian psychiatry.", "content": "Lessons from military psychiatry for civilian psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000781"}
{"pmid": "21000782", "title": "High lights on the psychology of infancy.", "content": "High lights on the psychology of infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000782"}
{"pmid": "21000783", "title": "Youth in search of a standard.", "content": "Youth in search of a standard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000783"}
{"pmid": "21000784", "title": "Help bolster those war marriages.", "content": "Help bolster those war marriages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000784"}
{"pmid": "21000786", "title": "Handling Africa.", "content": "Handling Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000786"}
{"pmid": "21000785", "title": "The veteran and his neuropsychiatric diagnosis.", "content": "The veteran and his neuropsychiatric diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000785"}
{"pmid": "21000787", "title": "Village planning in West Africa.", "content": "Village planning in West Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000787"}
{"pmid": "21000788", "title": "PALUDRINE, the new drug for malaria.", "content": "PALUDRINE, the new drug for malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000788"}
{"pmid": "21000789", "title": "Arabian medicine.", "content": "Arabian medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000789"}
{"pmid": "21000790", "title": "Twentieth century quarantine.", "content": "Twentieth century quarantine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000790"}
{"pmid": "21000791", "title": "Plans in the air [air ambulances].", "content": "Plans in the air [air ambulances].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000791"}
{"pmid": "21000792", "title": "Experiences of a battle-casualty.", "content": "Experiences of a battle-casualty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000792"}
{"pmid": "21000793", "title": "Highland home.", "content": "Highland home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000793"}
{"pmid": "21000794", "title": "The Livingstone method.", "content": "The Livingstone method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000794"}
{"pmid": "21000795", "title": "New Zealand's attack on tuberculosis.", "content": "New Zealand's attack on tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000795"}
{"pmid": "21000796", "title": "The veterinary inspection of dairy cattle in connection with diseases in human beings.", "content": "The veterinary inspection of dairy cattle in connection with diseases in human beings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000796"}
{"pmid": "21000797", "title": "The laboratory control of milk-borne disease.", "content": "The laboratory control of milk-borne disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000797"}
{"pmid": "21000798", "title": "Health hazards in the North Staffordshire pottery industry, 1688-1945.", "content": "Health hazards in the North Staffordshire pottery industry, 1688-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000798"}
{"pmid": "21000799", "title": "The management of municipal housing estates.", "content": "The management of municipal housing estates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000799"}
{"pmid": "21000800", "title": "The tuberculosis problem in state institutions in Ohio.", "content": "The tuberculosis problem in state institutions in Ohio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000800"}
{"pmid": "21000801", "title": "Tuberculosis in mental schools and hospitals in Ohio.", "content": "Tuberculosis in mental schools and hospitals in Ohio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000801"}
{"pmid": "21000802", "title": "The health of the American people, an historical survey.", "content": "The health of the American people, an historical survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000802"}
{"pmid": "21000803", "title": "Mental hygiene.", "content": "Mental hygiene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000803"}
{"pmid": "21000804", "title": "Role of governmental agencies in a national health program.", "content": "Role of governmental agencies in a national health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000804"}
{"pmid": "21000805", "title": "Convalescence and rehabilitation.", "content": "Convalescence and rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000805"}
{"pmid": "21000806", "title": "The place of the physician in modern society.", "content": "The place of the physician in modern society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000806"}
{"pmid": "21000807", "title": "The relationships between governmental and private responsibilities for national health.", "content": "The relationships between governmental and private responsibilities for national health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000807"}
{"pmid": "21000808", "title": "Public health experiences in the European Theatre of Operations.", "content": "Public health experiences in the European Theatre of Operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000808"}
{"pmid": "21000809", "title": "The background and antecedents of UNESCO.", "content": "The background and antecedents of UNESCO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000809"}
{"pmid": "21000810", "title": "The role of government in UNESCO.", "content": "The role of government in UNESCO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000810"}
{"pmid": "21000811", "title": "International relations among scientists.", "content": "International relations among scientists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000811"}
{"pmid": "21000812", "title": "Problems of international understanding.", "content": "Problems of international understanding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000812"}
{"pmid": "21000813", "title": "Brucella melitensis infections in Iowa.", "content": "Brucella melitensis infections in Iowa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000813"}
{"pmid": "21000814", "title": "Water samples for examination.", "content": "Water samples for examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000814"}
{"pmid": "21000815", "title": "Surplus property available from Federal Government.", "content": "Surplus property available from Federal Government.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000815"}
{"pmid": "21000816", "title": "The dynamic concept of thoracic topography; a critical review of present day teaching of visceral anatomy.", "content": "The dynamic concept of thoracic topography; a critical review of present day teaching of visceral anatomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000816"}
{"pmid": "21000817", "title": "Porencephaly.", "content": "Porencephaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000817"}
{"pmid": "21000818", "title": "Pneumatosis intestinalis; its roentgenologic diagnosis.", "content": "Pneumatosis intestinalis; its roentgenologic diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000818"}
{"pmid": "21000820", "title": "The roentgen diagnosis of volvulus of the sigmoid with intestinal obstruction.", "content": "The roentgen diagnosis of volvulus of the sigmoid with intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000820"}
{"pmid": "21000819", "title": "Secondary myelofibrosis with progressive generalized osseous eburnation.", "content": "Secondary myelofibrosis with progressive generalized osseous eburnation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000819"}
{"pmid": "21000821", "title": "Roentgen diagnosis of diseases of the neck of the bladder.", "content": "Roentgen diagnosis of diseases of the neck of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000821"}
{"pmid": "21000822", "title": "How exact is the roentgen diagnosis of heart valve calcifications?", "content": "How exact is the roentgen diagnosis of heart valve calcifications?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000822"}
{"pmid": "21000823", "title": "The effects of beta irradiation on the rabbit's eye.", "content": "The effects of beta irradiation on the rabbit's eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000823"}
{"pmid": "21000824", "title": "Cancer of the cervix; a study of the effect of interstitial radon needles as compared with roentgen therapy given through intravaginal cones.", "content": "Cancer of the cervix; a study of the effect of interstitial radon needles as compared with roentgen therapy given through intravaginal cones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000824"}
{"pmid": "21000826", "title": "Roentgenograms in relief.", "content": "Roentgenograms in relief.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000826"}
{"pmid": "21000825", "title": "Treatment of cutaneous hemangioma with radium.", "content": "Treatment of cutaneous hemangioma with radium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000825"}
{"pmid": "21000827", "title": "History of the American Society of X-Ray Technicians, 1920-1940.", "content": "History of the American Society of X-Ray Technicians, 1920-1940.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000827"}
{"pmid": "21000828", "title": "Medical benefits from atomic energy.", "content": "Medical benefits from atomic energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000828"}
{"pmid": "21000829", "title": "Temporomandibular joint.", "content": "Temporomandibular joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000829"}
{"pmid": "21000830", "title": "Radiography of the mastoid portion of the temporal bone in infants and children.", "content": "Radiography of the mastoid portion of the temporal bone in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000830"}
{"pmid": "21000832", "title": "Medical roentgen technology; the selection and training of the x-ray student.", "content": "Medical roentgen technology; the selection and training of the x-ray student.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000832"}
{"pmid": "21000831", "title": "The Potter-Bucky diaphragm.", "content": "The Potter-Bucky diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000831"}
{"pmid": "21000833", "title": "Featuring films.", "content": "Featuring films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000833"}
{"pmid": "21000834", "title": "Technique for locating areas on the scout roentgenogram by means of co-ordinating charts.", "content": "Technique for locating areas on the scout roentgenogram by means of co-ordinating charts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000834"}
{"pmid": "21000835", "title": "How to save time for the surgical staff during the hip-pinning procedure.", "content": "How to save time for the surgical staff during the hip-pinning procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000835"}
{"pmid": "21000836", "title": "Tube tilt projection in cholecystography.", "content": "Tube tilt projection in cholecystography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000836"}
{"pmid": "21000837", "title": "History of the American Society of X-ray Technicians. 1920-1940.", "content": "History of the American Society of X-ray Technicians. 1920-1940.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000837"}
{"pmid": "21000838", "title": "Contributions of some of Roentgen's predecessors; an historical sketch.", "content": "Contributions of some of Roentgen's predecessors; an historical sketch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000838"}
{"pmid": "21000839", "title": "Radiography of the gall bladder.", "content": "Radiography of the gall bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000839"}
{"pmid": "21000840", "title": "The roentgenographic examination of the carpus.", "content": "The roentgenographic examination of the carpus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000840"}
{"pmid": "21000841", "title": "Big jobs for little electrons.", "content": "Big jobs for little electrons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000841"}
{"pmid": "21000842", "title": "Radiographic examination of the sternum, postero-anterior position.", "content": "Radiographic examination of the sternum, postero-anterior position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000842"}
{"pmid": "21000843", "title": "Medical radiography in industry.", "content": "Medical radiography in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000843"}
{"pmid": "21000844", "title": "A simple method for radiography of chests which present marked variations in density.", "content": "A simple method for radiography of chests which present marked variations in density.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000844"}
{"pmid": "21000845", "title": "The use and abuse of x-ray tubes.", "content": "The use and abuse of x-ray tubes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000845"}
{"pmid": "21000846", "title": "A simple method of making direct negative copy from an x-ray film.", "content": "A simple method of making direct negative copy from an x-ray film.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000846"}
{"pmid": "21000847", "title": "Myelography.", "content": "Myelography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000847"}
{"pmid": "21000848", "title": "Intramuscular urography in children as carried out at the Children's Hospital of Pittsburgh.", "content": "Intramuscular urography in children as carried out at the Children's Hospital of Pittsburgh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000848"}
{"pmid": "21000849", "title": "The pyruvic acid method in deep clinical burns.", "content": "The pyruvic acid method in deep clinical burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000849"}
{"pmid": "21000850", "title": "The anemia of thermal burns.", "content": "The anemia of thermal burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000850"}
{"pmid": "21000851", "title": "Ascorbic acid, riboflavin, thiamin, and nicotinic acid in relation to severe injury, hemorrhage, and infection in the human.", "content": "Ascorbic acid, riboflavin, thiamin, and nicotinic acid in relation to severe injury, hemorrhage, and infection in the human.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000851"}
{"pmid": "21000852", "title": "The treatment of acute renal failure by peritoneal irrigation.", "content": "The treatment of acute renal failure by peritoneal irrigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000852"}
{"pmid": "21000853", "title": "The surgical treatment of congenital pulmonic stenosis.", "content": "The surgical treatment of congenital pulmonic stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000853"}
{"pmid": "21000854", "title": "Arterial repair in the treatment of aneurysms and arteriovenous fistulae; a report of 18 successful restorations.", "content": "Arterial repair in the treatment of aneurysms and arteriovenous fistulae; a report of 18 successful restorations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000854"}
{"pmid": "21000855", "title": "Roentgenologic kymographic studies of the heart in the presence of an arteriovenous fistula and their interpretation.", "content": "Roentgenologic kymographic studies of the heart in the presence of an arteriovenous fistula and their interpretation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000855"}
{"pmid": "21000856", "title": "Arteriovenous aneurysm of the vertebral vessels.", "content": "Arteriovenous aneurysm of the vertebral vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000856"}
{"pmid": "21000857", "title": "Studies on the use of gelatin sponge or foam as an hemostatic agent in experimental liver resections and injuries to large veins.", "content": "Studies on the use of gelatin sponge or foam as an hemostatic agent in experimental liver resections and injuries to large veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000857"}
{"pmid": "21000859", "title": "The clinicians' responsibility in the teaching of surgery.", "content": "The clinicians' responsibility in the teaching of surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000859"}
{"pmid": "21000858", "title": "Penicillin in the treatment of established surgical infections; a systematic study of 744 including 82 septicemias.", "content": "Penicillin in the treatment of established surgical infections; a systematic study of 744 including 82 septicemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000858"}
{"pmid": "21000860", "title": "The surgical lessons of the last five years of war and their application to postwar surgical practice.", "content": "The surgical lessons of the last five years of war and their application to postwar surgical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000860"}
{"pmid": "21000861", "title": "Some observations on head injuries and their complications.", "content": "Some observations on head injuries and their complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000861"}
{"pmid": "21000862", "title": "Abdominal injuries in the Second New Zealand Expeditionary Force during the Italian Campaign.", "content": "Abdominal injuries in the Second New Zealand Expeditionary Force during the Italian Campaign.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000862"}
{"pmid": "21000863", "title": "Anticoagulant effect of spleen.", "content": "Anticoagulant effect of spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000863"}
{"pmid": "21000865", "title": "Pulmonary hydatid disease; the sign of the camelote.", "content": "Pulmonary hydatid disease; the sign of the camelote.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000865"}
{"pmid": "21000866", "title": "Resection of the bladder neck in the female.", "content": "Resection of the bladder neck in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000866"}
{"pmid": "21000864", "title": "The influence of the hindlegs and pelvis on blood coagulation.", "content": "The influence of the hindlegs and pelvis on blood coagulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000864"}
{"pmid": "21000867", "title": "Empyema of intrahepatic gallbladder.", "content": "Empyema of intrahepatic gallbladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000867"}
{"pmid": "21000868", "title": "Chylous ascites, with report of a case treated by venous-peritoneal anastomosis.", "content": "Chylous ascites, with report of a case treated by venous-peritoneal anastomosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000868"}
{"pmid": "21000869", "title": "Repair of facial defects by low-neck pedicle flaps.", "content": "Repair of facial defects by low-neck pedicle flaps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000869"}
{"pmid": "21000870", "title": "Reconstruction for partial loss of ear.", "content": "Reconstruction for partial loss of ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000870"}
{"pmid": "21000871", "title": "Further reports on the use of composite free grafts of skin and cartilage from the ear.", "content": "Further reports on the use of composite free grafts of skin and cartilage from the ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000871"}
{"pmid": "21000872", "title": "Free ear lobe grafts of skin and fat; their value in reconstructions about the nostrils.", "content": "Free ear lobe grafts of skin and fat; their value in reconstructions about the nostrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000872"}
{"pmid": "21000873", "title": "The push-back operation for repair of cleft palate.", "content": "The push-back operation for repair of cleft palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000873"}
{"pmid": "21000874", "title": "Multiple excision and Z plastics in surface reconstruction.", "content": "Multiple excision and Z plastics in surface reconstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000874"}
{"pmid": "21000875", "title": "Report of a case of progressive facial hemiatrophy with pathological changes and surgical treatment.", "content": "Report of a case of progressive facial hemiatrophy with pathological changes and surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000875"}
{"pmid": "21000878", "title": "Congenital bands about the shoulder girdle.", "content": "Congenital bands about the shoulder girdle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000878"}
{"pmid": "21000879", "title": "The use of the masseter, temporalis and frontalis muscles in the correction of facial paralysis.", "content": "The use of the masseter, temporalis and frontalis muscles in the correction of facial paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000879"}
{"pmid": "21000877", "title": "The modified Dieffenbach operation for closure of large defects of lower lip and chin.", "content": "The modified Dieffenbach operation for closure of large defects of lower lip and chin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000877"}
{"pmid": "21000881", "title": "Subperiosteal mandibular resection with internal bar fixation.", "content": "Subperiosteal mandibular resection with internal bar fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000881"}
{"pmid": "21000880", "title": "Motion pictures as a teaching aid in plastic surgery.", "content": "Motion pictures as a teaching aid in plastic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000880"}
{"pmid": "21000882", "title": "The importance of the premaxilla and the philtrum in bilateral cleft lip.", "content": "The importance of the premaxilla and the philtrum in bilateral cleft lip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000882"}
{"pmid": "21000883", "title": "The rehabilitation program : plastic surgery.", "content": "The rehabilitation program : plastic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000883"}
{"pmid": "21000884", "title": "The use of streptomycin in experimental peritotis.", "content": "The use of streptomycin in experimental peritotis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000884"}
{"pmid": "21000876", "title": "Marked sensitivity to scarlet red ointment; loss of skin grafts and destruction of donor areas.", "content": "Marked sensitivity to scarlet red ointment; loss of skin grafts and destruction of donor areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000876"}
{"pmid": "21000885", "title": "Traumatic aneurysms; a study of forty-three cases an overseas general hospital.", "content": "Traumatic aneurysms; a study of forty-three cases an overseas general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000885"}
{"pmid": "21000886", "title": "A case of costoclavicular compression of the subclavian artery simulating arterial aneurysm.", "content": "A case of costoclavicular compression of the subclavian artery simulating arterial aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000886"}
{"pmid": "21000888", "title": "Air blast effect in a cave.", "content": "Air blast effect in a cave.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000888"}
{"pmid": "21000887", "title": "Battle casualties from the Philippine Islands; summary of experience with four thousand and forty cases.", "content": "Battle casualties from the Philippine Islands; summary of experience with four thousand and forty cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000887"}
{"pmid": "21000890", "title": "Malignant granular cell myoblastoma of the gluteal region.", "content": "Malignant granular cell myoblastoma of the gluteal region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000890"}
{"pmid": "21000889", "title": "Clinical manifestations of local shock and the treatment.", "content": "Clinical manifestations of local shock and the treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000889"}
{"pmid": "21000891", "title": "Dysgerminoma of the ovary.", "content": "Dysgerminoma of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000891"}
{"pmid": "21000893", "title": "Treatment of nonunion of the carpal navicular bone.", "content": "Treatment of nonunion of the carpal navicular bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000893"}
{"pmid": "21000894", "title": "A new method of bone plating.", "content": "A new method of bone plating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000894"}
{"pmid": "21000892", "title": "The use of tetraethylammonium in peripheral vascular disease and causalgic states; a new method for producing blockade of the autonomic ganglion.", "content": "The use of tetraethylammonium in peripheral vascular disease and causalgic states; a new method for producing blockade of the autonomic ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000892"}
{"pmid": "21000895", "title": "Congenital esophageal atresia with tracheoesophageal tula; a case report of successful end-to-end anatomosis.", "content": "Congenital esophageal atresia with tracheoesophageal tula; a case report of successful end-to-end anatomosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000895"}
{"pmid": "21000896", "title": "Treatment of esophageal achalasia or cardiospasm; report of four patients treated surgically.", "content": "Treatment of esophageal achalasia or cardiospasm; report of four patients treated surgically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000896"}
{"pmid": "21000897", "title": "Surgical removal of large retroperitoneal lumbar lioneuroma.", "content": "Surgical removal of large retroperitoneal lumbar lioneuroma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000897"}
{"pmid": "21000898", "title": "Hypoxemia of the fetus.", "content": "Hypoxemia of the fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000898"}
{"pmid": "21000899", "title": "Duodenal septum.", "content": "Duodenal septum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000899"}
{"pmid": "21000900", "title": "Meralgia paresthetica; new causal observations.", "content": "Meralgia paresthetica; new causal observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000900"}
{"pmid": "21000904", "title": "ROENTGEN therapy of pituitary adenomas.", "content": "ROENTGEN therapy of pituitary adenomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000904"}
{"pmid": "21000901", "title": "Protein depletion in pregnancy toxemia.", "content": "Protein depletion in pregnancy toxemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000901"}
{"pmid": "21000902", "title": "Electrotherapy of the levator muscle of the anus (levator ani) during the postpartum period and in some gynecologic conditions.", "content": "Electrotherapy of the levator muscle of the anus (levator ani) during the postpartum period and in some gynecologic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000902"}
{"pmid": "21000903", "title": "Further observations on prostigmine in delayed menstruation and pregnancy.", "content": "Further observations on prostigmine in delayed menstruation and pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000903"}
{"pmid": "21000905", "title": "Arsenical encephalopathy.", "content": "Arsenical encephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000905"}
{"pmid": "21000906", "title": "Current trends in the treatment of venereal disease in the United States of America.", "content": "Current trends in the treatment of venereal disease in the United States of America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000906"}
{"pmid": "21000907", "title": "Treatment of neurosyphilis; a comparison between malaria plus tryparsamide and malaria therapy.", "content": "Treatment of neurosyphilis; a comparison between malaria plus tryparsamide and malaria therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000907"}
{"pmid": "21000908", "title": "Changes in the cerebrospinal fluid in neurosyphilis after malaria therapy.", "content": "Changes in the cerebrospinal fluid in neurosyphilis after malaria therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000908"}
{"pmid": "21000909", "title": "Penicillin in the treatment of lymphogranuloma inguinale.", "content": "Penicillin in the treatment of lymphogranuloma inguinale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000909"}
{"pmid": "21000919", "title": "Salmonella typhimurium; a case of acute fatal enteritis among cattle.", "content": "Salmonella typhimurium; a case of acute fatal enteritis among cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000919"}
{"pmid": "21000920", "title": "Equine infectious anaemia; attempted cross immunity experiments.", "content": "Equine infectious anaemia; attempted cross immunity experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000920"}
{"pmid": "21000921", "title": "Studies in pullorum disease; bacteriological examination of tissues from fowls exposed to infection with Salmonella pullorum.", "content": "Studies in pullorum disease; bacteriological examination of tissues from fowls exposed to infection with Salmonella pullorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000921"}
{"pmid": "21000923", "title": "Veterinarians and artificial insemination.", "content": "Veterinarians and artificial insemination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000923"}
{"pmid": "21000922", "title": "Studies in pullorum disease; the effect of sulfamerazine on artificially and naturally infected chicks.", "content": "Studies in pullorum disease; the effect of sulfamerazine on artificially and naturally infected chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000922"}
{"pmid": "21000924", "title": "The virus of spontaneous encephalomyelitis of mice (Theiler's virus) in Venezuela.", "content": "The virus of spontaneous encephalomyelitis of mice (Theiler's virus) in Venezuela.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000924"}
{"pmid": "21000925", "title": "Historical sketches and memoirs; the general practitioner.", "content": "Historical sketches and memoirs; the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000925"}
{"pmid": "21000926", "title": "Effect of mucus volume on conception.", "content": "Effect of mucus volume on conception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000926"}
{"pmid": "21000927", "title": "Esophageal diverticulum.", "content": "Esophageal diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000927"}
{"pmid": "21000928", "title": "Sulfamerazine in paratyphoid disease of poults and chicks.", "content": "Sulfamerazine in paratyphoid disease of poults and chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000928"}
{"pmid": "21000929", "title": "Attempts to reproduce enteritis in swine.", "content": "Attempts to reproduce enteritis in swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000929"}
{"pmid": "21000930", "title": "Penicillin in the treatment of enzootic pneumonia of calves.", "content": "Penicillin in the treatment of enzootic pneumonia of calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000930"}
{"pmid": "21000931", "title": "MANGANESE deficiency.", "content": "MANGANESE deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000931"}
{"pmid": "21000932", "title": "The Army Veterinary Service.", "content": "The Army Veterinary Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000932"}
{"pmid": "21000933", "title": "PNEUMOENCEPHALITIS.", "content": "PNEUMOENCEPHALITIS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000933"}
{"pmid": "21000934", "title": "Equine gonadotropin in the functional sterility of dairy cattle.", "content": "Equine gonadotropin in the functional sterility of dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000934"}
{"pmid": "21000935", "title": "The infection of cattle with gastrointestinal parasites of sheep.", "content": "The infection of cattle with gastrointestinal parasites of sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000935"}
{"pmid": "21000936", "title": "Brucella abortus vaccine (strain 19) desiccated by lyophilization.", "content": "Brucella abortus vaccine (strain 19) desiccated by lyophilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000936"}
{"pmid": "21000937", "title": "The use of anthelmintics with wild species of sheep and goats.", "content": "The use of anthelmintics with wild species of sheep and goats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000937"}
{"pmid": "21000939", "title": "DANGER from moldy feed?", "content": "DANGER from moldy feed?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000939"}
{"pmid": "21000938", "title": "A case of pasteurella endocarditis in a pig.", "content": "A case of pasteurella endocarditis in a pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000938"}
{"pmid": "21000940", "title": "Some of the problems confronting the veterinary practitioner.", "content": "Some of the problems confronting the veterinary practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000940"}
{"pmid": "21000941", "title": "Allergic contact dermatitis in the horse.", "content": "Allergic contact dermatitis in the horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000941"}
{"pmid": "21000942", "title": "Further observations on the use of sulfathalidine phthalylsulfathiazole in the treatment of enteritis in suckling pigs.", "content": "Further observations on the use of sulfathalidine phthalylsulfathiazole in the treatment of enteritis in suckling pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000942"}
{"pmid": "21000943", "title": "SEEING eye.", "content": "SEEING eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000943"}
{"pmid": "21000944", "title": "The possibilities and dangers of artificial insemination.", "content": "The possibilities and dangers of artificial insemination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000944"}
{"pmid": "21000946", "title": "PENICILLIN preparations of the British Pharmacopoeia.", "content": "PENICILLIN preparations of the British Pharmacopoeia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000946"}
{"pmid": "21000945", "title": "Comparison between intracervical and intrauterine methods of artificial insemination.", "content": "Comparison between intracervical and intrauterine methods of artificial insemination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000945"}
{"pmid": "21000947", "title": "Hermaphrodism.", "content": "Hermaphrodism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000947"}
{"pmid": "21000948", "title": "Dislocated temporo-mandibular joint (cat).", "content": "Dislocated temporo-mandibular joint (cat).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000948"}
{"pmid": "21000949", "title": "Diseases of racing greyhounds.", "content": "Diseases of racing greyhounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000949"}
{"pmid": "21000950", "title": "Phenanthridinium compound 1553 in the treatment of T. congolense infection in grade cattle.", "content": "Phenanthridinium compound 1553 in the treatment of T. congolense infection in grade cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000950"}
{"pmid": "21000951", "title": "Penicillin in the treatment of mastitis.", "content": "Penicillin in the treatment of mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000951"}
{"pmid": "21000953", "title": "Therapeutic treatment of bovine mastitis.", "content": "Therapeutic treatment of bovine mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000953"}
{"pmid": "21000952", "title": "The use of electrical appliances in shrapnel detection.", "content": "The use of electrical appliances in shrapnel detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000952"}
{"pmid": "21000954", "title": "Foal mortality; retention of meconium.", "content": "Foal mortality; retention of meconium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000954"}
{"pmid": "21000955", "title": "The need for a national policy for the control of diseases of animals.", "content": "The need for a national policy for the control of diseases of animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000955"}
{"pmid": "21000957", "title": "The cat-influenza and cat-distemper group.", "content": "The cat-influenza and cat-distemper group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000957"}
{"pmid": "21000956", "title": "Leptospirosis with special reference to its occurrence in the dog.", "content": "Leptospirosis with special reference to its occurrence in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000956"}
{"pmid": "21000958", "title": "Strychnine poisoning.", "content": "Strychnine poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000958"}
{"pmid": "21000959", "title": "Disease of dogs following distemper.", "content": "Disease of dogs following distemper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000959"}
{"pmid": "21000960", "title": "Observations on the yellow teamite Hemitarsonemus latus (Banks) Ewing.", "content": "Observations on the yellow teamite Hemitarsonemus latus (Banks) Ewing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000960"}
{"pmid": "21000961", "title": "Repellency of pyrethrum and lethane sprays to mosquitos.", "content": "Repellency of pyrethrum and lethane sprays to mosquitos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000961"}
{"pmid": "21000962", "title": "The use of adhesive agents in DDT sprays.", "content": "The use of adhesive agents in DDT sprays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000962"}
{"pmid": "21000963", "title": "Factors influencing the interaction of insecticidal mists on flying insects; biological factors.", "content": "Factors influencing the interaction of insecticidal mists on flying insects; biological factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000963"}
{"pmid": "21000964", "title": "Notes on the bionomics of Anopheles sacharovi in Persia and Iraq.", "content": "Notes on the bionomics of Anopheles sacharovi in Persia and Iraq.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000964"}
{"pmid": "21000965", "title": "The control of trypanosomiasis by entomological means.", "content": "The control of trypanosomiasis by entomological means.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000965"}
{"pmid": "21000966", "title": "An artificially isolated generation of tsetse flies (Diptera).", "content": "An artificially isolated generation of tsetse flies (Diptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000966"}
{"pmid": "21000967", "title": "Common names of insects approved by the American Association of Economic Entomologists.", "content": "Common names of insects approved by the American Association of Economic Entomologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000967"}
{"pmid": "21000968", "title": "The insecticide situation.", "content": "The insecticide situation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000968"}
{"pmid": "21000969", "title": "Organic compounds effective against larvae of Anopheles quadrimaculatus; laboratory tests.", "content": "Organic compounds effective against larvae of Anopheles quadrimaculatus; laboratory tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000969"}
{"pmid": "21000970", "title": "DDT applied from the ground for control of mosquitoes.", "content": "DDT applied from the ground for control of mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000970"}
{"pmid": "21000971", "title": "Time required for Aedes vexans and A. lateralis larvae to obtain a lethal dose of several larvicides.", "content": "Time required for Aedes vexans and A. lateralis larvae to obtain a lethal dose of several larvicides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000971"}
{"pmid": "21000972", "title": "Factors influencing the rearing and maintenance of a laboratory colony of the body louse.", "content": "Factors influencing the rearing and maintenance of a laboratory colony of the body louse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000972"}
{"pmid": "21000973", "title": "High-frequency electric fields as lethal agents for insects.", "content": "High-frequency electric fields as lethal agents for insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000973"}
{"pmid": "21000975", "title": "Aerosols and their application.", "content": "Aerosols and their application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000975"}
{"pmid": "21000974", "title": "Observations on the airplane for application of sprays and dusts.", "content": "Observations on the airplane for application of sprays and dusts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000974"}
{"pmid": "21000976", "title": "Insect damage and germination of seed treated with DDT.", "content": "Insect damage and germination of seed treated with DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000976"}
{"pmid": "21000977", "title": "Toxicity of nitriles to stored-grain insects.", "content": "Toxicity of nitriles to stored-grain insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000977"}
{"pmid": "21000978", "title": "DDT in colloidal-type suspensions.", "content": "DDT in colloidal-type suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000978"}
{"pmid": "21000980", "title": "Gross infestations of the domestic rat with ectoparasites.", "content": "Gross infestations of the domestic rat with ectoparasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000980"}
{"pmid": "21000979", "title": "Effects of DDT on certain microbiological processes in the soil.", "content": "Effects of DDT on certain microbiological processes in the soil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000979"}
{"pmid": "21000981", "title": "Benzene hexachloride for animal parasites.", "content": "Benzene hexachloride for animal parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000981"}
{"pmid": "21000982", "title": "DDT used in control of latrine flies.", "content": "DDT used in control of latrine flies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000982"}
{"pmid": "21000983", "title": "The abundance and control of flies on a college campus.", "content": "The abundance and control of flies on a college campus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000983"}
{"pmid": "21000984", "title": "A laboratory method of flea culture.", "content": "A laboratory method of flea culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000984"}
{"pmid": "21000985", "title": "DDT for control of the biting sheep louse.", "content": "DDT for control of the biting sheep louse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000985"}
{"pmid": "21000986", "title": "[Principles of comparative parasitology as applied to the blood-sucking arthropoda].", "content": "[Principles of comparative parasitology as applied to the blood-sucking arthropoda].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000986"}
{"pmid": "21000987", "title": "[On certain groupings within the genus Haemaphysalis C. L. Koch and their taxonomic significance].", "content": "[On certain groupings within the genus Haemaphysalis C. L. Koch and their taxonomic significance].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000987"}
{"pmid": "21000988", "title": "[The encephalitides caused by viruses; experimental transmission of the virus of Japanese encephalitis to different strains of ticks].", "content": "[The encephalitides caused by viruses; experimental transmission of the virus of Japanese encephalitis to different strains of ticks].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000988"}
{"pmid": "21000989", "title": "[On tick-borne relapsing fever].", "content": "[On tick-borne relapsing fever].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000989"}
{"pmid": "21000990", "title": "[Treatment of scabies with sodium thiosulfate].", "content": "[Treatment of scabies with sodium thiosulfate].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000990"}
{"pmid": "21000991", "title": "[Mosquitoes of the barrage lakes].", "content": "[Mosquitoes of the barrage lakes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000991"}
{"pmid": "21000992", "title": "[Intermittent irrigation of the rice plantations as a preventive agrotechnical means of malaria control in Armenian SSR].", "content": "[Intermittent irrigation of the rice plantations as a preventive agrotechnical means of malaria control in Armenian SSR].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000992"}
{"pmid": "21000993", "title": "[Parasite-carrying and continuance of malaria tropica under conditions of Middle Asia].", "content": "[Parasite-carrying and continuance of malaria tropica under conditions of Middle Asia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000993"}
{"pmid": "21000994", "title": "[Further observations of gamostatic action of plasmocide in the combined treatment of malaria].", "content": "[Further observations of gamostatic action of plasmocide in the combined treatment of malaria].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000994"}
{"pmid": "21000995", "title": "[Action of acridine no. 8 and acriquin on the infection of A. maculipennis sacharovi with parasites of malaria tropica].", "content": "[Action of acridine no. 8 and acriquin on the infection of A. maculipennis sacharovi with parasites of malaria tropica].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000995"}
{"pmid": "21000996", "title": "[Differential diagnosis of plasmodial oocysts].", "content": "[Differential diagnosis of plasmodial oocysts].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000996"}
{"pmid": "21000997", "title": "[Results of malaria therapy with acriquine and plasmoquine].", "content": "[Results of malaria therapy with acriquine and plasmoquine].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000997"}
{"pmid": "21000998", "title": "[A case of two oncospheres in the egg of Hymenolepis nana].", "content": "[A case of two oncospheres in the egg of Hymenolepis nana].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000998"}
{"pmid": "21000999", "title": "[Microbiology in the Russian academy of sciences].", "content": "[Microbiology in the Russian academy of sciences].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21000999"}
{"pmid": "21001000", "title": "[Chemical aspect of the fixation of nitrogen by Azotobacter; influence of surface active substances.].", "content": "[Chemical aspect of the fixation of nitrogen by Azotobacter; influence of surface active substances.].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001000"}
{"pmid": "21001001", "title": "[\"Respiration\" of lactic acid bacteria].", "content": "[\"Respiration\" of lactic acid bacteria].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001001"}
{"pmid": "21001002", "title": "[Classification of Actinomycetales].", "content": "[Classification of Actinomycetales].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001002"}
{"pmid": "21001003", "title": "[Electron microscope studies on the structure of Actinomycetes].", "content": "[Electron microscope studies on the structure of Actinomycetes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001003"}
{"pmid": "21001004", "title": "[The nitrifying bacteria and Myxobacteria].", "content": "[The nitrifying bacteria and Myxobacteria].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001004"}
{"pmid": "21001005", "title": "[The growth factors and their influence on structure and life processes of yeasts].", "content": "[The growth factors and their influence on structure and life processes of yeasts].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001005"}
{"pmid": "21001006", "title": "[Morphology of polyhedra in silkworm disease].", "content": "[Morphology of polyhedra in silkworm disease].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001006"}
{"pmid": "21001007", "title": "[Concept of species in its application to the lower plants].", "content": "[Concept of species in its application to the lower plants].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001007"}
{"pmid": "21001008", "title": "[Aerial nutrition of soil bacteria].", "content": "[Aerial nutrition of soil bacteria].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001008"}
{"pmid": "21001009", "title": "[Imperfect forms of myxobacteria].", "content": "[Imperfect forms of myxobacteria].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001009"}
{"pmid": "21001010", "title": "[Engrafting of new virulence characters on nodule and some other bacteria].", "content": "[Engrafting of new virulence characters on nodule and some other bacteria].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001010"}
{"pmid": "21001011", "title": "[Thermophilic soil bacteria and their manner of spreading].", "content": "[Thermophilic soil bacteria and their manner of spreading].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001011"}
{"pmid": "21001012", "title": "[The chondriosome apparatus in cells of lower plants].", "content": "[The chondriosome apparatus in cells of lower plants].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001012"}
{"pmid": "21001013", "title": "[Biological method for the evaluation of biogenic elements in water reservoirs].", "content": "[Biological method for the evaluation of biogenic elements in water reservoirs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001013"}
{"pmid": "21001014", "title": "[Production of hydrocarbons from fats by microorganisms].", "content": "[Production of hydrocarbons from fats by microorganisms].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001014"}
{"pmid": "21001015", "title": "[The distribution of microorganisms in freshwater mud deposits].", "content": "[The distribution of microorganisms in freshwater mud deposits].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001015"}
{"pmid": "21001016", "title": "[Preservation of the light-producing ability of a bacterium for 23 years under laboratory conditions].", "content": "[Preservation of the light-producing ability of a bacterium for 23 years under laboratory conditions].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001016"}
{"pmid": "21001017", "title": "[Microorganisms of the eastern part of the Arctic Ocean].", "content": "[Microorganisms of the eastern part of the Arctic Ocean].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001017"}
{"pmid": "21001018", "title": "[Bacteria found in the Japan Sea].", "content": "[Bacteria found in the Japan Sea].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001018"}
{"pmid": "21001019", "title": "[Microbiological investigations of the lakes of northern Kazakhstan].", "content": "[Microbiological investigations of the lakes of northern Kazakhstan].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001019"}
{"pmid": "21001020", "title": "[Microbiological investigations of flood-plains lakes].", "content": "[Microbiological investigations of flood-plains lakes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001020"}
{"pmid": "21001021", "title": "[A new ferrobacterium from Yenisei River].", "content": "[A new ferrobacterium from Yenisei River].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001021"}
{"pmid": "21001022", "title": "Fungistatic action of diphenyl on some fruit and vegetable pathogens.", "content": "Fungistatic action of diphenyl on some fruit and vegetable pathogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001022"}
{"pmid": "21001023", "title": "Missing-plot techniques.", "content": "Missing-plot techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001023"}
{"pmid": "21001024", "title": "Limitations of the application of fourfold table analysis to hospital data.", "content": "Limitations of the application of fourfold table analysis to hospital data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001024"}
{"pmid": "21001025", "title": "Statistical methods for an incomplete experiment on a perennial crop.", "content": "Statistical methods for an incomplete experiment on a perennial crop.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001025"}
{"pmid": "21001026", "title": "[The Russian academy of sciences and faunal investigations in Russia].", "content": "[The Russian academy of sciences and faunal investigations in Russia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001026"}
{"pmid": "21001027", "title": "[Metabolism of nitrogen in plants].", "content": "[Metabolism of nitrogen in plants].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001027"}
{"pmid": "21001028", "title": "[Progress of comparative pathology and its significance for biology and medicine].", "content": "[Progress of comparative pathology and its significance for biology and medicine].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001028"}
{"pmid": "21001029", "title": "[Phosphoric acid and cell physiology].", "content": "[Phosphoric acid and cell physiology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001029"}
{"pmid": "21001030", "title": "[Variations in activity of enzymes as a means of regulation of functions in the animal body].", "content": "[Variations in activity of enzymes as a means of regulation of functions in the animal body].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001030"}
{"pmid": "21001031", "title": "[Sensory and subsensory reactions to external stimuli acting upon the human sense organs].", "content": "[Sensory and subsensory reactions to external stimuli acting upon the human sense organs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001031"}
{"pmid": "21001032", "title": "[Outline of the history of microbiology].", "content": "[Outline of the history of microbiology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001032"}
{"pmid": "21001033", "title": "[History of the microscope in the earliest period of the Academy of Sciences of St. Petersburg].", "content": "[History of the microscope in the earliest period of the Academy of Sciences of St. Petersburg].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001033"}
{"pmid": "21001034", "title": "[The problem of stability of organic forms (ontogeneses) in the process of evolution].", "content": "[The problem of stability of organic forms (ontogeneses) in the process of evolution].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001034"}
{"pmid": "21001035", "title": "[Influence of the character of dispersal on the ontogenesis of insects].", "content": "[Influence of the character of dispersal on the ontogenesis of insects].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001035"}
{"pmid": "21001036", "title": "[Geographical variability of fluctuations in numbers and evolution].", "content": "[Geographical variability of fluctuations in numbers and evolution].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001036"}
{"pmid": "21001037", "title": "[On the biology of feeding of some bottom fishes of the Black Sea].", "content": "[On the biology of feeding of some bottom fishes of the Black Sea].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001037"}
{"pmid": "21001042", "title": "The effect of nitrogen mustards on the viscosity of thymonucleate.", "content": "The effect of nitrogen mustards on the viscosity of thymonucleate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001042"}
{"pmid": "21001043", "title": "The effect of nitrogen mustards upon the ultraviolet absorption spectrum of thymonucleate, uracil and purines.", "content": "The effect of nitrogen mustards upon the ultraviolet absorption spectrum of thymonucleate, uracil and purines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001043"}
{"pmid": "21001044", "title": "Induction of neoplasia in vitro with a virus; experiments with rabbit skin grown in tissue culture and treated with Shope papilloma virus.", "content": "Induction of neoplasia in vitro with a virus; experiments with rabbit skin grown in tissue culture and treated with Shope papilloma virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001044"}
{"pmid": "21001045", "title": "Effect of progesterone on the development of mammary cancer in C3H mice.", "content": "Effect of progesterone on the development of mammary cancer in C3H mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001045"}
{"pmid": "21001038", "title": "Somatic and psychic factors in the causation of fibrositis.", "content": "Somatic and psychic factors in the causation of fibrositis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001038"}
{"pmid": "21001046", "title": "The influence of sex hormones upon the hepatic lesions produced by 2-acetaminofluorene.", "content": "The influence of sex hormones upon the hepatic lesions produced by 2-acetaminofluorene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001046"}
{"pmid": "21001047", "title": "Tumors of the salivary and parathyroid glands in rats fed with 2-acetylaminofluorene.", "content": "Tumors of the salivary and parathyroid glands in rats fed with 2-acetylaminofluorene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001047"}
{"pmid": "21001039", "title": "X-ray diagnosis of gout.", "content": "X-ray diagnosis of gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001039"}
{"pmid": "21001041", "title": "Gout, biochemical aspects.", "content": "Gout, biochemical aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001041"}
{"pmid": "21001049", "title": "Further studies of specific precipitin antiserums for the protein of cancer tissue; relation of the proteins of different malignant tissues to each other.", "content": "Further studies of specific precipitin antiserums for the protein of cancer tissue; relation of the proteins of different malignant tissues to each other.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001049"}
{"pmid": "21001048", "title": "Localization of stratum of maxium mitotic frequency in epidermal methylcholanthrene carcinogenesis in mice.", "content": "Localization of stratum of maxium mitotic frequency in epidermal methylcholanthrene carcinogenesis in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001048"}
{"pmid": "21001050", "title": "A transplantable 9,10-dimethyl-1,2-benzathracene sarcoma in the Syrian hamster.", "content": "A transplantable 9,10-dimethyl-1,2-benzathracene sarcoma in the Syrian hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001050"}
{"pmid": "21001052", "title": "The heart in primary systemic amyloidosis.", "content": "The heart in primary systemic amyloidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001052"}
{"pmid": "21001051", "title": "The relation between circulation time and the amount of the residual blood of the heart.", "content": "The relation between circulation time and the amount of the residual blood of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001051"}
{"pmid": "21001040", "title": "Clinical aspects of gout.", "content": "Clinical aspects of gout.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001040"}
{"pmid": "21001053", "title": "Some observations on the pathogenesis of edema in cardiac failure.", "content": "Some observations on the pathogenesis of edema in cardiac failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001053"}
{"pmid": "21001054", "title": "Coronary sinus rhythm.", "content": "Coronary sinus rhythm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001054"}
{"pmid": "21001055", "title": "Abnormalities of the respiratory pattern in patients with cardiac dyspnea.", "content": "Abnormalities of the respiratory pattern in patients with cardiac dyspnea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001055"}
{"pmid": "21001056", "title": "The influence of age on blood pressure; a study of 5,331 white male subjects.", "content": "The influence of age on blood pressure; a study of 5,331 white male subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001056"}
{"pmid": "21001058", "title": "Disadvantages of thiouracil treatment of angina pectoris.", "content": "Disadvantages of thiouracil treatment of angina pectoris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001058"}
{"pmid": "21001057", "title": "The T-wave of the precordial electrocardiogram at different age levels.", "content": "The T-wave of the precordial electrocardiogram at different age levels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001057"}
{"pmid": "21001059", "title": "Cardiovascular defects in Selective Service registrants.", "content": "Cardiovascular defects in Selective Service registrants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001059"}
{"pmid": "21001060", "title": "Acute pericarditis simulating coronary artery occlusion.", "content": "Acute pericarditis simulating coronary artery occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001060"}
{"pmid": "21001061", "title": "Bilateral pulmonary infarction and pneumothorax complicating hypertensive, coronary heart disease with myocardial infarction; report of a case.", "content": "Bilateral pulmonary infarction and pneumothorax complicating hypertensive, coronary heart disease with myocardial infarction; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001061"}
{"pmid": "21001062", "title": "Purpuric manifestations of rheumatic fever and acute glomerulonephritis.", "content": "Purpuric manifestations of rheumatic fever and acute glomerulonephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001062"}
{"pmid": "21001063", "title": "Photoelectric spectrophotometry applied to the analysis of mixtures, and vitamin A oils.", "content": "Photoelectric spectrophotometry applied to the analysis of mixtures, and vitamin A oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001063"}
{"pmid": "21001064", "title": "Some modern aids to spectrochemical analysis.", "content": "Some modern aids to spectrochemical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001064"}
{"pmid": "21001065", "title": "Applications of spectrographic analysis to soil investigations.", "content": "Applications of spectrographic analysis to soil investigations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001065"}
{"pmid": "21001066", "title": "Spectrographic analysis of rare and high purity materials.", "content": "Spectrographic analysis of rare and high purity materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001066"}
{"pmid": "21001067", "title": "A micro filter stick for use in spectrographic analysis.", "content": "A micro filter stick for use in spectrographic analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001067"}
{"pmid": "21001068", "title": "The transformation of biological responses with special reference to vitamin-D assays.", "content": "The transformation of biological responses with special reference to vitamin-D assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001068"}
{"pmid": "21001069", "title": "An absorptiometric method for magnesium in zinc-base die-casting alloys.", "content": "An absorptiometric method for magnesium in zinc-base die-casting alloys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001069"}
{"pmid": "21001070", "title": "Report on the microbiological assay of riboflavine and nicotinic acid.", "content": "Report on the microbiological assay of riboflavine and nicotinic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001070"}
{"pmid": "21001071", "title": "The genetical requirements of bio-assays with higher organisms.", "content": "The genetical requirements of bio-assays with higher organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001071"}
{"pmid": "21001072", "title": "The genetical aspects of bio-assays with microorganisms.", "content": "The genetical aspects of bio-assays with microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001072"}
{"pmid": "21001073", "title": "The determination of small amounts of arsenic.", "content": "The determination of small amounts of arsenic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001073"}
{"pmid": "21001074", "title": "The determination of lead in creta praeparata.", "content": "The determination of lead in creta praeparata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001074"}
{"pmid": "21001075", "title": "The determination of the pyridine content of technical pyridine.", "content": "The determination of the pyridine content of technical pyridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001075"}
{"pmid": "21001076", "title": "The determination of nickel by precipitation with dimethylglyoxime.", "content": "The determination of nickel by precipitation with dimethylglyoxime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001076"}
{"pmid": "21001077", "title": "The determination of silicon in nickel alloys.", "content": "The determination of silicon in nickel alloys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001077"}
{"pmid": "21001078", "title": "The direct photometric determination of aluminium with 8-hydroxyquinoline.", "content": "The direct photometric determination of aluminium with 8-hydroxyquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001078"}
{"pmid": "21001079", "title": "The structure of urea-formaldehyde resins.", "content": "The structure of urea-formaldehyde resins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001079"}
{"pmid": "21001080", "title": "The mechanism of the hydrolysis of chlorine.", "content": "The mechanism of the hydrolysis of chlorine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001080"}
{"pmid": "21001081", "title": "The preparation and partial aromatization of 1,4-cholestadienone-3 by the dienonephenol rearrangement.", "content": "The preparation and partial aromatization of 1,4-cholestadienone-3 by the dienonephenol rearrangement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001081"}
{"pmid": "21001082", "title": "The dienonephenol rearrangement applied to chrysene derivatives; the synthesis of 3-hydroxy-1-methylchrysene and related compounds.", "content": "The dienonephenol rearrangement applied to chrysene derivatives; the synthesis of 3-hydroxy-1-methylchrysene and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001082"}
{"pmid": "21001083", "title": "Antitubercular studies; 1,1,1,-trichloro-2,2-bis (para-aminophenyl)-ethane.", "content": "Antitubercular studies; 1,1,1,-trichloro-2,2-bis (para-aminophenyl)-ethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001083"}
{"pmid": "21001084", "title": "The nature of the variable hydration of precipitated barium sulfate.", "content": "The nature of the variable hydration of precipitated barium sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001084"}
{"pmid": "21001085", "title": "The measurement and calculation of hydrogen ion concentrations in saline acetate and phosphate buffers.", "content": "The measurement and calculation of hydrogen ion concentrations in saline acetate and phosphate buffers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001085"}
{"pmid": "21001086", "title": "Heats of dilution of aqueous solutions of alpha- and beta-alanine at 250.", "content": "Heats of dilution of aqueous solutions of alpha- and beta-alanine at 250.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001086"}
{"pmid": "21001087", "title": "Thermal data; the heat capacity, entropy and free energy of urea.", "content": "Thermal data; the heat capacity, entropy and free energy of urea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001087"}
{"pmid": "21001088", "title": "The action of copper sulfate on the phenylosazones of the sugars; the D-,L- and D,L-arabinose phenylosotriazoles.", "content": "The action of copper sulfate on the phenylosazones of the sugars; the D-,L- and D,L-arabinose phenylosotriazoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001088"}
{"pmid": "21001089", "title": "The 3,5-benzylidene and 3,5-methylene acetals of gluco-gulo-hepitol.", "content": "The 3,5-benzylidene and 3,5-methylene acetals of gluco-gulo-hepitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001089"}
{"pmid": "21001090", "title": "The preparation of some monoalkyl- and symmetrical dialkylethylenediamines.", "content": "The preparation of some monoalkyl- and symmetrical dialkylethylenediamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001090"}
{"pmid": "21001091", "title": "A simplified synthesis of N-aryl-glycamines.", "content": "A simplified synthesis of N-aryl-glycamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001091"}
{"pmid": "21001092", "title": "Structure and activity of sulfanilamides.", "content": "Structure and activity of sulfanilamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001092"}
{"pmid": "21001093", "title": "Copolymerization; the composition distribution curve.", "content": "Copolymerization; the composition distribution curve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001093"}
{"pmid": "21001094", "title": "Multilayer adsorption equations.", "content": "Multilayer adsorption equations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001094"}
{"pmid": "21001095", "title": "Arsenicals containing the 1,2,5-triazole nucleus.", "content": "Arsenicals containing the 1,2,5-triazole nucleus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001095"}
{"pmid": "21001096", "title": "A study of alternate methods for the alkylation of aceto-acetic esters.", "content": "A study of alternate methods for the alkylation of aceto-acetic esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001096"}
{"pmid": "21001097", "title": "Pyridinium analogs of the pressor amines; the benzene series.", "content": "Pyridinium analogs of the pressor amines; the benzene series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001097"}
{"pmid": "21001098", "title": "Some 4-amino-7-chloroquinoline derivatives.", "content": "Some 4-amino-7-chloroquinoline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001098"}
{"pmid": "21001099", "title": "Antimalarials; 7-chloro-4-hydroxy- and 4,7-dichloro-1-methylcarbostyrils.", "content": "Antimalarials; 7-chloro-4-hydroxy- and 4,7-dichloro-1-methylcarbostyrils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001099"}
{"pmid": "21001100", "title": "Antimalarials; alpha-alkyl and dialkylaminomethyl-2-phenyl-4-quinolinemethanols.", "content": "Antimalarials; alpha-alkyl and dialkylaminomethyl-2-phenyl-4-quinolinemethanols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001100"}
{"pmid": "21001101", "title": "alpha-Dialkylaminomethyl-4-quinolinemethanols substituted in the 2-position.", "content": "alpha-Dialkylaminomethyl-4-quinolinemethanols substituted in the 2-position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001101"}
{"pmid": "21001102", "title": "Studies in the quinoline series; the preparation of some dialkylaminomethyl-4-quinoline methanols.", "content": "Studies in the quinoline series; the preparation of some dialkylaminomethyl-4-quinoline methanols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001102"}
{"pmid": "21001103", "title": "Studies in the quinoline series; the preparation of some alpha-dialkylaminomethyl-2-quinoline methanols.", "content": "Studies in the quinoline series; the preparation of some alpha-dialkylaminomethyl-2-quinoline methanols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001103"}
{"pmid": "21001104", "title": "Studies in the quinoline series; the preparation of some alpha-dialkylamino-methyl-8-quinoline methanols.", "content": "Studies in the quinoline series; the preparation of some alpha-dialkylamino-methyl-8-quinoline methanols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001104"}
{"pmid": "21001105", "title": "alpha-(3-Dialkylaminopropy)-2-phenyl-6-methoxy-4-quinolinemethanols.", "content": "alpha-(3-Dialkylaminopropy)-2-phenyl-6-methoxy-4-quinolinemethanols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001105"}
{"pmid": "21001106", "title": "Studies in the quinoline series; the preparation of some substituted lepidylamines.", "content": "Studies in the quinoline series; the preparation of some substituted lepidylamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001106"}
{"pmid": "21001107", "title": "3-Keto-6(beta)-hydroxycholanic acid and 3 (alpha)-hydroxy-6-ketocholanic acid.", "content": "3-Keto-6(beta)-hydroxycholanic acid and 3 (alpha)-hydroxy-6-ketocholanic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001107"}
{"pmid": "21001108", "title": "Degradation of hyodesoxycholic acid.", "content": "Degradation of hyodesoxycholic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001108"}
{"pmid": "21001109", "title": "The pressure-volume relations of the gaseous methylamines at 0 degrees and reduced pressures.", "content": "The pressure-volume relations of the gaseous methylamines at 0 degrees and reduced pressures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001109"}
{"pmid": "21001110", "title": "The nature of the N-H bond in the porphyrins.", "content": "The nature of the N-H bond in the porphyrins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001110"}
{"pmid": "21001111", "title": "Syntheses of certain derivatives of phenylalanine and of auramine in studies of antimalarial action.", "content": "Syntheses of certain derivatives of phenylalanine and of auramine in studies of antimalarial action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001111"}
{"pmid": "21001112", "title": "Aminoalkylphenols as antimalarials; simple substituted alpha-aminocresols.", "content": "Aminoalkylphenols as antimalarials; simple substituted alpha-aminocresols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001112"}
{"pmid": "21001113", "title": "Some basically substituted quinazolines.", "content": "Some basically substituted quinazolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001113"}
{"pmid": "21001114", "title": "Some derivatives of 3-amino-4-(1-diethylamino-4-pentylamino)-chlorobenzene.", "content": "Some derivatives of 3-amino-4-(1-diethylamino-4-pentylamino)-chlorobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001114"}
{"pmid": "21001116", "title": "2-Methoxy-6-chloro-9-(N-substituted-amino)-acridines; compounds derived from cyclic secondary amines.", "content": "2-Methoxy-6-chloro-9-(N-substituted-amino)-acridines; compounds derived from cyclic secondary amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001116"}
{"pmid": "21001115", "title": "N-substituted 2-methoxy-6-chloro-9-aminoacridines derived from unsymmetrical aliphatic amines.", "content": "N-substituted 2-methoxy-6-chloro-9-aminoacridines derived from unsymmetrical aliphatic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001115"}
{"pmid": "21001117", "title": "Pyridinium analogs of the pressor amines; the guaiacol series.", "content": "Pyridinium analogs of the pressor amines; the guaiacol series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001117"}
{"pmid": "21001118", "title": "Antispasmodics, VIII.", "content": "Antispasmodics, VIII.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001118"}
{"pmid": "21001119", "title": "X-ray investigation of glycerides; diffraction analysis of 1-monoarachidin (1-monoeicosanoate).", "content": "X-ray investigation of glycerides; diffraction analysis of 1-monoarachidin (1-monoeicosanoate).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001119"}
{"pmid": "21001120", "title": "The preparation of stibonic acids by the Scheller reaction.", "content": "The preparation of stibonic acids by the Scheller reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001120"}
{"pmid": "21001121", "title": "Some reactions of arylstibonic acids.", "content": "Some reactions of arylstibonic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001121"}
{"pmid": "21001122", "title": "The structure of arylstibonic acids.", "content": "The structure of arylstibonic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001122"}
{"pmid": "21001123", "title": "Pyrimido [4,5-beta] pyrazines; synthesis of 6,7-symmetrically substituted derivatives.", "content": "Pyrimido [4,5-beta] pyrazines; synthesis of 6,7-symmetrically substituted derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001123"}
{"pmid": "21001124", "title": "Heterocyclic amines with antithistaminic activity.", "content": "Heterocyclic amines with antithistaminic activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001124"}
{"pmid": "21001125", "title": "Some methylquinolines patterned as open models of atebrin.", "content": "Some methylquinolines patterned as open models of atebrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001125"}
{"pmid": "21001126", "title": "Chemical interactions of amino compounds and sugars, I.", "content": "Chemical interactions of amino compounds and sugars, I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001126"}
{"pmid": "21001127", "title": "The dielectric properties of liquid mixtures.", "content": "The dielectric properties of liquid mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001127"}
{"pmid": "21001128", "title": "The standard electrode potentials of the mercury-mercurous sulfate electrode in methanol at 20, 25, 30 and 35 degrees.", "content": "The standard electrode potentials of the mercury-mercurous sulfate electrode in methanol at 20, 25, 30 and 35 degrees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001128"}
{"pmid": "21001129", "title": "Polarographic reduction of carbon dioxide; polymerization and adsorption at the dropping mercury cathode.", "content": "Polarographic reduction of carbon dioxide; polymerization and adsorption at the dropping mercury cathode.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001129"}
{"pmid": "21001130", "title": "Polarographic reduction of carbon dioxide; description and interpretation of the waves.", "content": "Polarographic reduction of carbon dioxide; description and interpretation of the waves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001130"}
{"pmid": "21001131", "title": "Regulator theory in emulsion polymerization; chain transfer of low molecular weight mercaptans in emulsion and oil-phase.", "content": "Regulator theory in emulsion polymerization; chain transfer of low molecular weight mercaptans in emulsion and oil-phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001131"}
{"pmid": "21001132", "title": "Regulator theory in emulsion polymerization; control of reaction rate by diffusion for high molecular weight mercaptans.", "content": "Regulator theory in emulsion polymerization; control of reaction rate by diffusion for high molecular weight mercaptans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001132"}
{"pmid": "21001133", "title": "Regulator theory in emulsion polymerization; regulator reaction in copolymerizing systems.", "content": "Regulator theory in emulsion polymerization; regulator reaction in copolymerizing systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001133"}
{"pmid": "21001134", "title": "Synthetic preparation of 2-chloro-2'-hydroxydiethyl sulfide, reaction with cysteine and valine, and measurement of reaction rate in aqueous media.", "content": "Synthetic preparation of 2-chloro-2'-hydroxydiethyl sulfide, reaction with cysteine and valine, and measurement of reaction rate in aqueous media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001134"}
{"pmid": "21001135", "title": "Dialkylaminoalkyl diarylthiolacetates.", "content": "Dialkylaminoalkyl diarylthiolacetates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001135"}
{"pmid": "21001136", "title": "Branched-chain fatty acids; a further study of the preparation of ketones and keto esters by means of organocadmium reagents.", "content": "Branched-chain fatty acids; a further study of the preparation of ketones and keto esters by means of organocadmium reagents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001136"}
{"pmid": "21001137", "title": "Streptomyces antibiotics; the degradation of streptomycin and dihydrostreptomycin with ethyl mercaptan.", "content": "Streptomyces antibiotics; the degradation of streptomycin and dihydrostreptomycin with ethyl mercaptan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001137"}
{"pmid": "21001138", "title": "Dehydration of cholic acid.", "content": "Dehydration of cholic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001138"}
{"pmid": "21001140", "title": "Some heterocyclic acetic acids in plant hormone tests.", "content": "Some heterocyclic acetic acids in plant hormone tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001140"}
{"pmid": "21001139", "title": "N-derivatives of para-arsanilic acid.", "content": "N-derivatives of para-arsanilic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001139"}
{"pmid": "21001141", "title": "A convenient synthesis of 5-methyltryptophan.", "content": "A convenient synthesis of 5-methyltryptophan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001141"}
{"pmid": "21001142", "title": "The purification of hesperidin with formamide.", "content": "The purification of hesperidin with formamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001142"}
{"pmid": "21001143", "title": "Acetylation of d-mannose phenylhydrazone.", "content": "Acetylation of d-mannose phenylhydrazone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001143"}
{"pmid": "21001144", "title": "A new derivative of kojic acid.", "content": "A new derivative of kojic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001144"}
{"pmid": "21001145", "title": "Degradative studies on streptomycin.", "content": "Degradative studies on streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001145"}
{"pmid": "21001146", "title": "Protein-phytic acid relationship in peanuts and cottonseed.", "content": "Protein-phytic acid relationship in peanuts and cottonseed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001146"}
{"pmid": "21001147", "title": "Distribution of intravenously injected fructose and glucose between blood and brain.", "content": "Distribution of intravenously injected fructose and glucose between blood and brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001147"}
{"pmid": "21001148", "title": "Phosphoric esters of biological importance; the synthesis of glucose-6-phosphate.", "content": "Phosphoric esters of biological importance; the synthesis of glucose-6-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001148"}
{"pmid": "21001149", "title": "Reaction of thiol compounds with peroxidase and hydrogen peroxide.", "content": "Reaction of thiol compounds with peroxidase and hydrogen peroxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001149"}
{"pmid": "21001150", "title": "The dissociation constants of organic calcium complexes.", "content": "The dissociation constants of organic calcium complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001150"}
{"pmid": "21001151", "title": "Factors affecting the enzymic destruction of carotene in alfalfa.", "content": "Factors affecting the enzymic destruction of carotene in alfalfa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001151"}
{"pmid": "21001152", "title": "Tryptophane studies; the effect of niacin on the utilization of tryptophane.", "content": "Tryptophane studies; the effect of niacin on the utilization of tryptophane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001152"}
{"pmid": "21001153", "title": "A spectrophotometric method for the measurement of ribonuclease activity.", "content": "A spectrophotometric method for the measurement of ribonuclease activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001153"}
{"pmid": "21001155", "title": "A dietary factor essential for guinea pigs; the isolation of the antistiffness factor from cane juice.", "content": "A dietary factor essential for guinea pigs; the isolation of the antistiffness factor from cane juice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001155"}
{"pmid": "21001154", "title": "Steroids derived from bile acids; 3,9-epoxy-delta 11-cholenic acid and closely related compounds.", "content": "Steroids derived from bile acids; 3,9-epoxy-delta 11-cholenic acid and closely related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001154"}
{"pmid": "21001156", "title": "The rôle of dimethyl- and monomethylaminoethanol in transmethylation reactions in vivo.", "content": "The rôle of dimethyl- and monomethylaminoethanol in transmethylation reactions in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001156"}
{"pmid": "21001157", "title": "Gamma-methylproline.", "content": "Gamma-methylproline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001157"}
{"pmid": "21001158", "title": "Infra-red absorption spectra of steroids; estrogens.", "content": "Infra-red absorption spectra of steroids; estrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001158"}
{"pmid": "21001159", "title": "The antiscorbutic properties of 3-methylascorbic acid.", "content": "The antiscorbutic properties of 3-methylascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001159"}
{"pmid": "21001160", "title": "Urinary excretion of alpha-amino nitrogen following intravenous administration of amino acid mixtures.", "content": "Urinary excretion of alpha-amino nitrogen following intravenous administration of amino acid mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001160"}
{"pmid": "21001161", "title": "Studies on the mercapturic acid synthesis in animals; on the synthesis of mercapturic acids in man.", "content": "Studies on the mercapturic acid synthesis in animals; on the synthesis of mercapturic acids in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001161"}
{"pmid": "21001162", "title": "Photometric determination of total cholesterol in plasma of serum by a modified Liebermann-Burchard reaction.", "content": "Photometric determination of total cholesterol in plasma of serum by a modified Liebermann-Burchard reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001162"}
{"pmid": "21001163", "title": "The effects of insulin in fluoride-poisoned rats.", "content": "The effects of insulin in fluoride-poisoned rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001163"}
{"pmid": "21001164", "title": "The carboxylase activity of jack beans (Canavalia ensiformis) and soy beans (Glycine hispida).", "content": "The carboxylase activity of jack beans (Canavalia ensiformis) and soy beans (Glycine hispida).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001164"}
{"pmid": "21001165", "title": "Isolation of a peptide of para-aminobenzoic acid from yeast.", "content": "Isolation of a peptide of para-aminobenzoic acid from yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001165"}
{"pmid": "21001166", "title": "Spectrophotometric studies; the crystallographic and optical properties of the hemoglobin of man in comparison with those of other species.", "content": "Spectrophotometric studies; the crystallographic and optical properties of the hemoglobin of man in comparison with those of other species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001166"}
{"pmid": "21001167", "title": "A spectrophotometric method for the determination of penicillin.", "content": "A spectrophotometric method for the determination of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001167"}
{"pmid": "21001168", "title": "Ferritin; increase of the protein apoferritin in the gastrointestinal mucosa as a direct response to iron feeding; the function of ferritin in the regulation of iron absorption.", "content": "Ferritin; increase of the protein apoferritin in the gastrointestinal mucosa as a direct response to iron feeding; the function of ferritin in the regulation of iron absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001168"}
{"pmid": "21001170", "title": "The specificity of carboxypeptidase.", "content": "The specificity of carboxypeptidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001170"}
{"pmid": "21001169", "title": "Phosphorus compounds in animal tissues; a comparison of methods for the estimation of nucleic acids.", "content": "Phosphorus compounds in animal tissues; a comparison of methods for the estimation of nucleic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001169"}
{"pmid": "21001171", "title": "The effect of amino acids on the microbial growth inhibition produced by thienylalanine.", "content": "The effect of amino acids on the microbial growth inhibition produced by thienylalanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001171"}
{"pmid": "21001172", "title": "The oxidation of ascorbic acid by oxidized adrenalin and cytochrome c.", "content": "The oxidation of ascorbic acid by oxidized adrenalin and cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001172"}
{"pmid": "21001173", "title": "The lipotropic action of manganese.", "content": "The lipotropic action of manganese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001173"}
{"pmid": "21001174", "title": "The partial synthesis of urinary delta 5-androstene-3 (beta),- 16,17-triol.", "content": "The partial synthesis of urinary delta 5-androstene-3 (beta),- 16,17-triol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001174"}
{"pmid": "21001175", "title": "Ineffective utilization of conjugated pteroylglutamic (folic) acid in pernicious anemia.", "content": "Ineffective utilization of conjugated pteroylglutamic (folic) acid in pernicious anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001175"}
{"pmid": "21001176", "title": "The replacement of para-aminobenzoic acid in the growth of a mutant strain of Escherichia coli.", "content": "The replacement of para-aminobenzoic acid in the growth of a mutant strain of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001176"}
{"pmid": "21001178", "title": "The microdetermination of serine and ethanolamine in phospholipide hydrolysates.", "content": "The microdetermination of serine and ethanolamine in phospholipide hydrolysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001178"}
{"pmid": "21001179", "title": "On the activation of catalase.", "content": "On the activation of catalase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001179"}
{"pmid": "21001177", "title": "Partial synthesis of compounds related to adrenal cortical hormones; preparation of an 11-keto bile acid.", "content": "Partial synthesis of compounds related to adrenal cortical hormones; preparation of an 11-keto bile acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001177"}
{"pmid": "21001180", "title": "The cytochrome c-cyanide complex.", "content": "The cytochrome c-cyanide complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001180"}
{"pmid": "21001181", "title": "Biophysical studies of blood plasma proteins; separation and purification of a new globulin from normal human plasma.", "content": "Biophysical studies of blood plasma proteins; separation and purification of a new globulin from normal human plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001181"}
{"pmid": "21001182", "title": "Paired feeding in the study of the counteraction by nicotinic acid and tryptophane of the growth-depressing effect of corn in rats.", "content": "Paired feeding in the study of the counteraction by nicotinic acid and tryptophane of the growth-depressing effect of corn in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001182"}
{"pmid": "21001183", "title": "The oxidation of catechol by tyrosinase.", "content": "The oxidation of catechol by tyrosinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001183"}
{"pmid": "21001184", "title": "The vitamin B6 group; biological assay of pyridoxal, pyridoxamine, and pyridoxine.", "content": "The vitamin B6 group; biological assay of pyridoxal, pyridoxamine, and pyridoxine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001184"}
{"pmid": "21001186", "title": "The utilization of a color correction equation with the Kober reagent for the estimation of the estrogens in human urine with low estrogen content.", "content": "The utilization of a color correction equation with the Kober reagent for the estimation of the estrogens in human urine with low estrogen content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001186"}
{"pmid": "21001185", "title": "Chemical determination of riboflavin.", "content": "Chemical determination of riboflavin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001185"}
{"pmid": "21001187", "title": "Studies on the inhibition of enzyme systems involving cytochrome c.", "content": "Studies on the inhibition of enzyme systems involving cytochrome c.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001187"}
{"pmid": "21001188", "title": "Fluorometric studies of the riboflavin contents of muscle and liver.", "content": "Fluorometric studies of the riboflavin contents of muscle and liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001188"}
{"pmid": "21001189", "title": "A note on the conversion in vivo of the S-benzyl-N-methyl derivatives of cysteine and homocysteine to the N-acetyl-S-benzyl derivatives of cysteine and homocysteine.", "content": "A note on the conversion in vivo of the S-benzyl-N-methyl derivatives of cysteine and homocysteine to the N-acetyl-S-benzyl derivatives of cysteine and homocysteine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001189"}
{"pmid": "21001190", "title": "Phosphoglycocyamine.", "content": "Phosphoglycocyamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001190"}
{"pmid": "21001191", "title": "A method for the determination of alloxan.", "content": "A method for the determination of alloxan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001191"}
{"pmid": "21001192", "title": "The metabolism of sulfur; the distribution of urinary sulfur and the excretion of keto acids after the oral administration of some derivatives of cystine and methionine to the rabbit.", "content": "The metabolism of sulfur; the distribution of urinary sulfur and the excretion of keto acids after the oral administration of some derivatives of cystine and methionine to the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001192"}
{"pmid": "21001193", "title": "The development of the cytochrome oxidase and succinoxidase systems in the chick embryo.", "content": "The development of the cytochrome oxidase and succinoxidase systems in the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001193"}
{"pmid": "21001194", "title": "The oxidation of higher fatty acids in heart muscle suspensions.", "content": "The oxidation of higher fatty acids in heart muscle suspensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001194"}
{"pmid": "21001195", "title": "Studies in carbohydrate metabolism; the distribution of deuterium in a sample of deuterio glucose excreted by a diabetic rabbit.", "content": "Studies in carbohydrate metabolism; the distribution of deuterium in a sample of deuterio glucose excreted by a diabetic rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001195"}
{"pmid": "21001196", "title": "Studies in carbohydrate metabolism; the origin of the stable hydrogen in glycogen formed from various precursors.", "content": "Studies in carbohydrate metabolism; the origin of the stable hydrogen in glycogen formed from various precursors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001196"}
{"pmid": "21001197", "title": "Dietary protein and protoporphyrin formation in the rat.", "content": "Dietary protein and protoporphyrin formation in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001197"}
{"pmid": "21001198", "title": "Colorimetric determination of canavanine.", "content": "Colorimetric determination of canavanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001198"}
{"pmid": "21001199", "title": "Observations on sulfur amino acid deficiencies in rats; chemical and morphological changes in the blood.", "content": "Observations on sulfur amino acid deficiencies in rats; chemical and morphological changes in the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001199"}
{"pmid": "21001200", "title": "Dietary protein and the vitamin B6 content of mouse tissue.", "content": "Dietary protein and the vitamin B6 content of mouse tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001200"}
{"pmid": "21001201", "title": "Partial synthesis of compounds related to adrenal cortical hormones; stepwise degradation of the side chain of 3 (alpha), 11 (alpha)-dihydroxycholanic acid.", "content": "Partial synthesis of compounds related to adrenal cortical hormones; stepwise degradation of the side chain of 3 (alpha), 11 (alpha)-dihydroxycholanic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001201"}
{"pmid": "21001202", "title": "Partial synthesis of compounds related to adrenal cortical hormones; preparation of 3 (alpha), 11 (alpha)-dihydroxyetiocholanic acid from etiodesoxycholic acid.", "content": "Partial synthesis of compounds related to adrenal cortical hormones; preparation of 3 (alpha), 11 (alpha)-dihydroxyetiocholanic acid from etiodesoxycholic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001202"}
{"pmid": "21001203", "title": "The relation of the thyroxine content of the thyroid gland and of the level of protein-bound iodine of plasma to iodine intake.", "content": "The relation of the thyroxine content of the thyroid gland and of the level of protein-bound iodine of plasma to iodine intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001203"}
{"pmid": "21001204", "title": "On the energy source of the action potential in the electric organ of Electrophorus electricus.", "content": "On the energy source of the action potential in the electric organ of Electrophorus electricus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001204"}
{"pmid": "21001205", "title": "The isolation of pectic substances from softwoods.", "content": "The isolation of pectic substances from softwoods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001205"}
{"pmid": "21001206", "title": "Isolation and characterization of the T2 bacteriophage of Escherichia coli.", "content": "Isolation and characterization of the T2 bacteriophage of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001206"}
{"pmid": "21001207", "title": "Sedimentation characters and pH stability of the T2 bacteriophage of Escherichia coli.", "content": "Sedimentation characters and pH stability of the T2 bacteriophage of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001207"}
{"pmid": "21001208", "title": "Chemical analysis of the T2 bacteriophage and its host, Escherichia coli (strain B).", "content": "Chemical analysis of the T2 bacteriophage and its host, Escherichia coli (strain B).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001208"}
{"pmid": "21001209", "title": "The effect of formaldehyde on the acidic and basic properties of wool.", "content": "The effect of formaldehyde on the acidic and basic properties of wool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001209"}
{"pmid": "21001210", "title": "Gasometric and photometric measurement of arginase activity.", "content": "Gasometric and photometric measurement of arginase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001210"}
{"pmid": "21001211", "title": "The assay of animal tissues for respiratory enzymes; the malic dehydrogenas system.", "content": "The assay of animal tissues for respiratory enzymes; the malic dehydrogenas system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001211"}
{"pmid": "21001212", "title": "Hydrolysis procedures for the determination of tryptophane in proteins and food stuffs by the microbiological procedure.", "content": "Hydrolysis procedures for the determination of tryptophane in proteins and food stuffs by the microbiological procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001212"}
{"pmid": "21001213", "title": "A synthesis of 1(+)-glutamine.", "content": "A synthesis of 1(+)-glutamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001213"}
{"pmid": "21001214", "title": "The metabolism of sulfur; isocysteine.", "content": "The metabolism of sulfur; isocysteine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001214"}
{"pmid": "21001215", "title": "Microbiological determination of methionine in proteins and foodstuffs.", "content": "Microbiological determination of methionine in proteins and foodstuffs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001215"}
{"pmid": "21001216", "title": "The chromatographic separation of bile acids the separation of cholic and desoxycholic acid.", "content": "The chromatographic separation of bile acids the separation of cholic and desoxycholic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001216"}
{"pmid": "21001217", "title": "Partial oxidation of hyodesoxycholic acid.", "content": "Partial oxidation of hyodesoxycholic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001217"}
{"pmid": "21001218", "title": "The effect of the synthetic pteroylglutamic acid on the feathering of chickens.", "content": "The effect of the synthetic pteroylglutamic acid on the feathering of chickens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001218"}
{"pmid": "21001219", "title": "The determination of ascorbic acid; a simplification of the Roe method.", "content": "The determination of ascorbic acid; a simplification of the Roe method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001219"}
{"pmid": "21001220", "title": "Oxidation of stereoisomers of the inositol group by Acetobacter suboxydans.", "content": "Oxidation of stereoisomers of the inositol group by Acetobacter suboxydans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001220"}
{"pmid": "21001221", "title": "Detection of biochemical mutants of microorganisms.", "content": "Detection of biochemical mutants of microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001221"}
{"pmid": "21001222", "title": "Biotin and avidin intake and liver cholesterol.", "content": "Biotin and avidin intake and liver cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001222"}
{"pmid": "21001223", "title": "The oxidation of octanoate by normal and leucemic mouse liver homogenates.", "content": "The oxidation of octanoate by normal and leucemic mouse liver homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001223"}
{"pmid": "21001224", "title": "The growth-stimulating effect of a heat-labile factor in liver extract on rats fed a natural diet.", "content": "The growth-stimulating effect of a heat-labile factor in liver extract on rats fed a natural diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001224"}
{"pmid": "21001225", "title": "A substance in incubated rat heart augmenting the cholinesterase activity of heart muscle.", "content": "A substance in incubated rat heart augmenting the cholinesterase activity of heart muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001225"}
{"pmid": "21001226", "title": "The influence of a strepogenin concentrate on the metabolism of glutamic acid by Streptococcus faecalis.", "content": "The influence of a strepogenin concentrate on the metabolism of glutamic acid by Streptococcus faecalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001226"}
{"pmid": "21001227", "title": "Action of choline and fat on the formation of phospholipides in the intestine.", "content": "Action of choline and fat on the formation of phospholipides in the intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001227"}
{"pmid": "21001228", "title": "The adenosinetriphosphatase activity in the presence of creatine.", "content": "The adenosinetriphosphatase activity in the presence of creatine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001228"}
{"pmid": "21001229", "title": "A labile iron pool.", "content": "A labile iron pool.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001229"}
{"pmid": "21001230", "title": "Clinical and histologic study of an impacted third molar causing referred pain.", "content": "Clinical and histologic study of an impacted third molar causing referred pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001230"}
{"pmid": "21001231", "title": "Experimental study of pulp changes produced in the decompression chamber.", "content": "Experimental study of pulp changes produced in the decompression chamber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001231"}
{"pmid": "21001232", "title": "Comparative studies of the feeding of fluorides as they occur in purified bone meal powder, defluorinated phosphate and sodium fluoride, in dogs.", "content": "Comparative studies of the feeding of fluorides as they occur in purified bone meal powder, defluorinated phosphate and sodium fluoride, in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001232"}
{"pmid": "21001233", "title": "The effect of sodium fluoride on the teeth and blood calcium and inorganic phosphorus levels of rachitic rats.", "content": "The effect of sodium fluoride on the teeth and blood calcium and inorganic phosphorus levels of rachitic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001233"}
{"pmid": "21001234", "title": "The effect of cadmium on the production of caries in the rat.", "content": "The effect of cadmium on the production of caries in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001234"}
{"pmid": "21001235", "title": "Dental caries in the Syrian hamster; the character and distribution of lesions.", "content": "Dental caries in the Syrian hamster; the character and distribution of lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001235"}
{"pmid": "21001236", "title": "Serial sections of undecalcified enamel.", "content": "Serial sections of undecalcified enamel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001236"}
{"pmid": "21001237", "title": "A technic for observing minute changes on tooth surfaces.", "content": "A technic for observing minute changes on tooth surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001237"}
{"pmid": "21001238", "title": "Bands of Schreger.", "content": "Bands of Schreger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001238"}
{"pmid": "21001239", "title": "Odontoblasts and dentinogenesis (a histochemical study).", "content": "Odontoblasts and dentinogenesis (a histochemical study).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001239"}
{"pmid": "21001241", "title": "A demonstrable line on extracted teeth indicating the location of the outer border of the epithelial attachment.", "content": "A demonstrable line on extracted teeth indicating the location of the outer border of the epithelial attachment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001241"}
{"pmid": "21001240", "title": "Further observations on vital staining of dentin and enamel.", "content": "Further observations on vital staining of dentin and enamel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001240"}
{"pmid": "21001243", "title": "Vulcanite moulds for making acrylic teeth.", "content": "Vulcanite moulds for making acrylic teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001243"}
{"pmid": "21001242", "title": "Bilateral fibro-osteoma of the maxillae in a monkey.", "content": "Bilateral fibro-osteoma of the maxillae in a monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001242"}
{"pmid": "21001244", "title": "Deplorable dental conditions of South Africans.", "content": "Deplorable dental conditions of South Africans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001244"}
{"pmid": "21001245", "title": "Acrylic teeth.", "content": "Acrylic teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001245"}
{"pmid": "21001246", "title": "The choice of a general anaesthetic.", "content": "The choice of a general anaesthetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001246"}
{"pmid": "21001247", "title": "Penicillin and the dental surgeon.", "content": "Penicillin and the dental surgeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001247"}
{"pmid": "21001248", "title": "Notes on dentures, jackets, crowns and bridges.", "content": "Notes on dentures, jackets, crowns and bridges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001248"}
{"pmid": "21001252", "title": "Vehicles in topical dermatologic therapy; their functions and physicochemical characteristics.", "content": "Vehicles in topical dermatologic therapy; their functions and physicochemical characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001252"}
{"pmid": "21001253", "title": "Dermatitis from a large dose of penicillin taken orally; report of a case.", "content": "Dermatitis from a large dose of penicillin taken orally; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001253"}
{"pmid": "21001254", "title": "Contact dermatitis from penicillin; the source of the antigen.", "content": "Contact dermatitis from penicillin; the source of the antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001254"}
{"pmid": "21001255", "title": "Observations on the cause and transmission of granuloma inguinale.", "content": "Observations on the cause and transmission of granuloma inguinale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001255"}
{"pmid": "21001256", "title": "Rhinoscleroma; observations based on a study of two hundred cases.", "content": "Rhinoscleroma; observations based on a study of two hundred cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001256"}
{"pmid": "21001257", "title": "Mammalian pigmentation; the problem of the pigmentary mechanism studied by means of the respiration of tissues.", "content": "Mammalian pigmentation; the problem of the pigmentary mechanism studied by means of the respiration of tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001257"}
{"pmid": "21001258", "title": "Diagnostic significance of the culture method in cutaneous leishmaniasis (Oriental sore).", "content": "Diagnostic significance of the culture method in cutaneous leishmaniasis (Oriental sore).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001258"}
{"pmid": "21001259", "title": "Aspergillus infection of the nails.", "content": "Aspergillus infection of the nails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001259"}
{"pmid": "21001260", "title": "Dermatophytosis due to combined infection with trichophyton interdigitale and trichophyton purpureum; report of a case.", "content": "Dermatophytosis due to combined infection with trichophyton interdigitale and trichophyton purpureum; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001260"}
{"pmid": "21001261", "title": "Erythema multiforme and erythema nodosum; a comparative study of fifty-four patients.", "content": "Erythema multiforme and erythema nodosum; a comparative study of fifty-four patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001261"}
{"pmid": "21001262", "title": "Progressive syphilitic optic atrophy benefited by combined penicillin and fever therapy; report of a case.", "content": "Progressive syphilitic optic atrophy benefited by combined penicillin and fever therapy; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001262"}
{"pmid": "21001263", "title": "Biopsy guide.", "content": "Biopsy guide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001263"}
{"pmid": "21001264", "title": "Chronic lupus erythematosus of the face and the tongue.", "content": "Chronic lupus erythematosus of the face and the tongue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001264"}
{"pmid": "21001265", "title": "Lichen planus of the mucous membrane and the eyelid.", "content": "Lichen planus of the mucous membrane and the eyelid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001265"}
{"pmid": "21001266", "title": "Abortive von Recklinghausen's disease.", "content": "Abortive von Recklinghausen's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001266"}
{"pmid": "21001268", "title": "Bullous lichen planus.", "content": "Bullous lichen planus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001268"}
{"pmid": "21001269", "title": "Atrophoderma hypoestrogenicum.", "content": "Atrophoderma hypoestrogenicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001269"}
{"pmid": "21001270", "title": "Dermatitis medicamentosa.", "content": "Dermatitis medicamentosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001270"}
{"pmid": "21001271", "title": "Keratosis blennorrhagica.", "content": "Keratosis blennorrhagica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001271"}
{"pmid": "21001272", "title": "Macular atrophy.", "content": "Macular atrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001272"}
{"pmid": "21001273", "title": "Keratosis follicularis.", "content": "Keratosis follicularis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001273"}
{"pmid": "21001274", "title": "Synovial lesion of the finger.", "content": "Synovial lesion of the finger.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001274"}
{"pmid": "21001276", "title": "Granuloma annulare disseminated type.", "content": "Granuloma annulare disseminated type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001276"}
{"pmid": "21001275", "title": "A case for diagnosis (sporotrichosis?).", "content": "A case for diagnosis (sporotrichosis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001275"}
{"pmid": "21001277", "title": "Liquefying nodular panniculitis.", "content": "Liquefying nodular panniculitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001277"}
{"pmid": "21001278", "title": "Anetoderma erythematosum of Jadassohn (dermatitis maculosa atrophicans).", "content": "Anetoderma erythematosum of Jadassohn (dermatitis maculosa atrophicans).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001278"}
{"pmid": "21001279", "title": "A case for diagnosis (maculosquamous eruption resembling lupus erythematosus?).", "content": "A case for diagnosis (maculosquamous eruption resembling lupus erythematosus?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001279"}
{"pmid": "21001280", "title": "A case for diagnosis (contact dermatitis?).", "content": "A case for diagnosis (contact dermatitis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001280"}
{"pmid": "21001281", "title": "Urticaria pigmentosa of bullous type.", "content": "Urticaria pigmentosa of bullous type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001281"}
{"pmid": "21001282", "title": "Neural leprosy (maculoanesthetic form?).", "content": "Neural leprosy (maculoanesthetic form?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001282"}
{"pmid": "21001283", "title": "Localized hyperhidrosis.", "content": "Localized hyperhidrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001283"}
{"pmid": "21001284", "title": "A case for diagnosis (eruption of chest and back, aggravated by sunlight).", "content": "A case for diagnosis (eruption of chest and back, aggravated by sunlight).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001284"}
{"pmid": "21001285", "title": "Koilonychia.", "content": "Koilonychia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001285"}
{"pmid": "21001286", "title": "A case for diagnosis (toxic erythema; lupus erythematosus?).", "content": "A case for diagnosis (toxic erythema; lupus erythematosus?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001286"}
{"pmid": "21001287", "title": "A case for diagnosis (trichokryptomania?).", "content": "A case for diagnosis (trichokryptomania?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001287"}
{"pmid": "21001288", "title": "Leiomyoma.", "content": "Leiomyoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001288"}
{"pmid": "21001291", "title": "A case for diagnosis (parapsoriasis?).", "content": "A case for diagnosis (parapsoriasis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001291"}
{"pmid": "21001290", "title": "Lichen planus hypertrophicus.", "content": "Lichen planus hypertrophicus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001290"}
{"pmid": "21001289", "title": "Pyoderma treated with penicillin ointment.", "content": "Pyoderma treated with penicillin ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001289"}
{"pmid": "21001292", "title": "A case for diagnosis (panniculitis, nodular, nonsuppurative?).", "content": "A case for diagnosis (panniculitis, nodular, nonsuppurative?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001292"}
{"pmid": "21001293", "title": "A case for diagnosis (psoriasis of the palms and soles; syphilis?).", "content": "A case for diagnosis (psoriasis of the palms and soles; syphilis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001293"}
{"pmid": "21001294", "title": "A case for diagnosis (psoriasis; lichen planus; erythroplasia of Queyrat?).", "content": "A case for diagnosis (psoriasis; lichen planus; erythroplasia of Queyrat?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001294"}
{"pmid": "21001295", "title": "A case for diagnosis (sarcoid; leprosy; lupus erythematosus?).", "content": "A case for diagnosis (sarcoid; leprosy; lupus erythematosus?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001295"}
{"pmid": "21001297", "title": "Lupus vulgaris.", "content": "Lupus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001297"}
{"pmid": "21001296", "title": "A case for diagnosis (sycosis vulgaris and folliculitis of the scalp?).", "content": "A case for diagnosis (sycosis vulgaris and folliculitis of the scalp?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001296"}
{"pmid": "21001298", "title": "A case for diagnosis (cutaneous leishmaniasis?).", "content": "A case for diagnosis (cutaneous leishmaniasis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001298"}
{"pmid": "21001299", "title": "A case for diagnosis (purpura annularis telangiectodes?).", "content": "A case for diagnosis (purpura annularis telangiectodes?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001299"}
{"pmid": "21001300", "title": "Parapsoriasis guttata (pityriasis lichenoides chronica).", "content": "Parapsoriasis guttata (pityriasis lichenoides chronica).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001300"}
{"pmid": "21001301", "title": "A case for diagnosis (fat necrosis?).", "content": "A case for diagnosis (fat necrosis?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001301"}
{"pmid": "21001302", "title": "Acanthosis nigricans juvenilis?", "content": "Acanthosis nigricans juvenilis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001302"}
{"pmid": "21001303", "title": "Epidermolysis bullosa (acquisita).", "content": "Epidermolysis bullosa (acquisita).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001303"}
{"pmid": "21001304", "title": "Mycosis fungoides.", "content": "Mycosis fungoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001304"}
{"pmid": "21001305", "title": "Symmetric melanosis (of genetic origin?).", "content": "Symmetric melanosis (of genetic origin?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001305"}
{"pmid": "21001306", "title": "Subacute disseminated lupus erythematosus.", "content": "Subacute disseminated lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001306"}
{"pmid": "21001307", "title": "Lupus erythematosus.", "content": "Lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001307"}
{"pmid": "21001308", "title": "Hairy and pigmented nevus.", "content": "Hairy and pigmented nevus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001308"}
{"pmid": "21001309", "title": "Fixed eruption due to a drug (sulfathiazole).", "content": "Fixed eruption due to a drug (sulfathiazole).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001309"}
{"pmid": "21001310", "title": "Ainhum.", "content": "Ainhum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001310"}
{"pmid": "21001312", "title": "Lupus vulgaris.", "content": "Lupus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001312"}
{"pmid": "21001313", "title": "Sarcoidosis with ulceration.", "content": "Sarcoidosis with ulceration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001313"}
{"pmid": "21001314", "title": "Sarcoidosis.", "content": "Sarcoidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001314"}
{"pmid": "21001315", "title": "Amyloidosis of skin.", "content": "Amyloidosis of skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001315"}
{"pmid": "21001316", "title": "Trophic ulcers following nerve resection.", "content": "Trophic ulcers following nerve resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001316"}
{"pmid": "21001317", "title": "Methods for determining the erythrocyte count on the photoelectric colorimeter.", "content": "Methods for determining the erythrocyte count on the photoelectric colorimeter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001317"}
{"pmid": "21001318", "title": "Ovalocytosis; an anomaly of the red blood cells.", "content": "Ovalocytosis; an anomaly of the red blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001318"}
{"pmid": "21001319", "title": "Laboratory survey of malaria inoculata.", "content": "Laboratory survey of malaria inoculata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001319"}
{"pmid": "21001320", "title": "The dawn of medical technology.", "content": "The dawn of medical technology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001320"}
{"pmid": "21001321", "title": "A C.S.L.T. in the Eastern Arctic; a blood survey of the Eskimos.", "content": "A C.S.L.T. in the Eastern Arctic; a blood survey of the Eskimos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001321"}
{"pmid": "21001322", "title": "Laboratory tests with antibiotic substances.", "content": "Laboratory tests with antibiotic substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001322"}
{"pmid": "21001323", "title": "Some technical and physiological aspects of anaemia.", "content": "Some technical and physiological aspects of anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001323"}
{"pmid": "21001324", "title": "Blood smears and the halometer.", "content": "Blood smears and the halometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001324"}
{"pmid": "21001325", "title": "The role of intestinal bacteria in nutrition.", "content": "The role of intestinal bacteria in nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001325"}
{"pmid": "21001326", "title": "Nutrition research in China.", "content": "Nutrition research in China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001326"}
{"pmid": "21001327", "title": "Constructing a congee kitchen for relief feeding in China.", "content": "Constructing a congee kitchen for relief feeding in China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001327"}
{"pmid": "21001328", "title": "The nutrition problem of Mexico.", "content": "The nutrition problem of Mexico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001328"}
{"pmid": "21001329", "title": "A recent dietary study of a rural community in Greece.", "content": "A recent dietary study of a rural community in Greece.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001329"}
{"pmid": "21001330", "title": "Wartime food rationing in the Netherlands.", "content": "Wartime food rationing in the Netherlands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001330"}
{"pmid": "21001331", "title": "The effect of a relief vegetable protein diet on normal human subjects.", "content": "The effect of a relief vegetable protein diet on normal human subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001331"}
{"pmid": "21001332", "title": "Nutritional observations in pediatric practice.", "content": "Nutritional observations in pediatric practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001332"}
{"pmid": "21001333", "title": "Observations of dietary intake in two children's homes.", "content": "Observations of dietary intake in two children's homes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001333"}
{"pmid": "21001334", "title": "Gastroscopy and its relationship to roentgenology in the diagnosis of carcinoma of the stomach.", "content": "Gastroscopy and its relationship to roentgenology in the diagnosis of carcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001334"}
{"pmid": "21001335", "title": "Backache due to intra-abdominal disease.", "content": "Backache due to intra-abdominal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001335"}
{"pmid": "21001336", "title": "A note on bacteriological and parasitic studies of the intestinal contents of patients with sprue.", "content": "A note on bacteriological and parasitic studies of the intestinal contents of patients with sprue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001336"}
{"pmid": "21001337", "title": "Peptic ulcer of the esophagus; report of a patient with 10-yr. follow-up.", "content": "Peptic ulcer of the esophagus; report of a patient with 10-yr. follow-up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001337"}
{"pmid": "21001338", "title": "Hematemesis; a study of underlying causes.", "content": "Hematemesis; a study of underlying causes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001338"}
{"pmid": "21001339", "title": "Gastric secretion in duodenal ulcer in remission; response to the caffeine test meal.", "content": "Gastric secretion in duodenal ulcer in remission; response to the caffeine test meal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001339"}
{"pmid": "21001340", "title": "Vascular changes in the mucosa in experimental nutritional gastritis.", "content": "Vascular changes in the mucosa in experimental nutritional gastritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001340"}
{"pmid": "21001341", "title": "A case of lung tumor with prominent abdominal changes.", "content": "A case of lung tumor with prominent abdominal changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001341"}
{"pmid": "21001342", "title": "Acute enterocolitis and death resulting from a markedly hypertonic enema.", "content": "Acute enterocolitis and death resulting from a markedly hypertonic enema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001342"}
{"pmid": "21001343", "title": "In memoriam; the carbonic anhydrase theory of gastric acid secretion.", "content": "In memoriam; the carbonic anhydrase theory of gastric acid secretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001343"}
{"pmid": "21001344", "title": "Concerning the carbonic anhydrase theory of HCl formation.", "content": "Concerning the carbonic anhydrase theory of HCl formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001344"}
{"pmid": "21001345", "title": "The anoxia test as an aid in the diagnosis of coronary insufficiency.", "content": "The anoxia test as an aid in the diagnosis of coronary insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001345"}
{"pmid": "21001346", "title": "Laboratory aids in the diagnosis and management of infectious (epidemic) hepatitis; analysis of results obtained by studies on 34 volunteers during the early and convalescent stages of induced hepatitis.", "content": "Laboratory aids in the diagnosis and management of infectious (epidemic) hepatitis; analysis of results obtained by studies on 34 volunteers during the early and convalescent stages of induced hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001346"}
{"pmid": "21001347", "title": "The treatment of postoperative biliary dyskinesia; a report of eight cases of endocholedochal sphincterotomy.", "content": "The treatment of postoperative biliary dyskinesia; a report of eight cases of endocholedochal sphincterotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001347"}
{"pmid": "21001348", "title": "Nutritional deficiency as a probable cause of hepatic damage in repatriated prisoners of war.", "content": "Nutritional deficiency as a probable cause of hepatic damage in repatriated prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001348"}
{"pmid": "21001349", "title": "Amino acid alimentation in gastro-intestinal diseases.", "content": "Amino acid alimentation in gastro-intestinal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001349"}
{"pmid": "21001350", "title": "The history of hemorrhage in peptic ulcer.", "content": "The history of hemorrhage in peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001350"}
{"pmid": "21001351", "title": "The relationship of trauma to the perforation of peptic ulcer.", "content": "The relationship of trauma to the perforation of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001351"}
{"pmid": "21001352", "title": "Hypertrophic pyloric stenosis in the adult.", "content": "Hypertrophic pyloric stenosis in the adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001352"}
{"pmid": "21001353", "title": "The effect of B vitamins on intestinal absorption and food utilization; studies in rats and diets deficient in certain B vitamins and during recovery from such diets.", "content": "The effect of B vitamins on intestinal absorption and food utilization; studies in rats and diets deficient in certain B vitamins and during recovery from such diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001353"}
{"pmid": "21001354", "title": "Primary amyloidosis of liver, spleen, kidneys, suprarenals, bone marrow, pancreas, lymph nodes, and blood vessels in lungs.", "content": "Primary amyloidosis of liver, spleen, kidneys, suprarenals, bone marrow, pancreas, lymph nodes, and blood vessels in lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001354"}
{"pmid": "21001355", "title": "Unusual initial onset of ulcerative colitis with exsanguinating bowel hemorrhage.", "content": "Unusual initial onset of ulcerative colitis with exsanguinating bowel hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001355"}
{"pmid": "21001357", "title": "The specificity of the water test as a diagnostic procedure in Addison's disease.", "content": "The specificity of the water test as a diagnostic procedure in Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001357"}
{"pmid": "21001356", "title": "Animal experiments relating to water diuresis tests for adrenal insufficiency.", "content": "Animal experiments relating to water diuresis tests for adrenal insufficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001356"}
{"pmid": "21001358", "title": "Changes in the prominence of the eyes in various thyroid states.", "content": "Changes in the prominence of the eyes in various thyroid states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001358"}
{"pmid": "21001359", "title": "The nature of benadryl activity: glucose tolerance curves.", "content": "The nature of benadryl activity: glucose tolerance curves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001359"}
{"pmid": "21001360", "title": "Fundamental principles of the law of damages in medico-legal cases.", "content": "Fundamental principles of the law of damages in medico-legal cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001360"}
{"pmid": "21001361", "title": "Can judgements recovered as a result of automobile accidents be discharged by the subsequent bankruptcy proceedings of the defendant?", "content": "Can judgements recovered as a result of automobile accidents be discharged by the subsequent bankruptcy proceedings of the defendant?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001361"}
{"pmid": "21001362", "title": "ADMISSIBILITY of hospital records as business entries.", "content": "ADMISSIBILITY of hospital records as business entries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001362"}
{"pmid": "21001364", "title": "Blood-group frequencies in New Zealand and Maori soldiers.", "content": "Blood-group frequencies in New Zealand and Maori soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001364"}
{"pmid": "21001363", "title": "Familial data on 144 cases of anencephaly, spina bifida and congenital hydrocephaly.", "content": "Familial data on 144 cases of anencephaly, spina bifida and congenital hydrocephaly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001363"}
{"pmid": "21001365", "title": "A serological and genetical study of multiple antibodies formed in response to blood transfusion by a patient with lupus erythematosus diffusus.", "content": "A serological and genetical study of multiple antibodies formed in response to blood transfusion by a patient with lupus erythematosus diffusus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001365"}
{"pmid": "21001366", "title": "Scores for ranked data in school examination practice.", "content": "Scores for ranked data in school examination practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001366"}
{"pmid": "21001367", "title": "The cumulants of the distribution of Fisher's mu 11 and mu 31 scores used in the detection and estimation of linkage in man.", "content": "The cumulants of the distribution of Fisher's mu 11 and mu 31 scores used in the detection and estimation of linkage in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001367"}
{"pmid": "21001368", "title": "Pedigree of nystagmus, myopia and congenital eye defects with mental deficiency.", "content": "Pedigree of nystagmus, myopia and congenital eye defects with mental deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001368"}
{"pmid": "21001369", "title": "On the familial appearances of maternal and foetal incompatibility.", "content": "On the familial appearances of maternal and foetal incompatibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001369"}
{"pmid": "21001370", "title": "Genetical antigenic incompatibility as a possible cause of the toxaemias occuring late in pregnancy.", "content": "Genetical antigenic incompatibility as a possible cause of the toxaemias occuring late in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001370"}
{"pmid": "21001371", "title": "The fitting of gene frequencies to data on rhesus reactions.", "content": "The fitting of gene frequencies to data on rhesus reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001371"}
{"pmid": "21001372", "title": "Microspermia in an individual from a family of unusually high sex ratio and low fertility.", "content": "Microspermia in an individual from a family of unusually high sex ratio and low fertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001372"}
{"pmid": "21001373", "title": "[Some necessary supplements to the modern notion of the mechanism of labor].", "content": "[Some necessary supplements to the modern notion of the mechanism of labor].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001373"}
{"pmid": "21001374", "title": "[Contribution to the etiology of spontaneous abortion].", "content": "[Contribution to the etiology of spontaneous abortion].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001374"}
{"pmid": "21001375", "title": "[Subfebrile states in pregnancy].", "content": "[Subfebrile states in pregnancy].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001375"}
{"pmid": "21001376", "title": "[Experimental and clinical data on the effect of thymophysin on the uterus].", "content": "[Experimental and clinical data on the effect of thymophysin on the uterus].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001376"}
{"pmid": "21001377", "title": "[Effect of ephedrine on the uterus].", "content": "[Effect of ephedrine on the uterus].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001377"}
{"pmid": "21001378", "title": "[Vitamin C metabolism in the second half of complicated pregnancy].", "content": "[Vitamin C metabolism in the second half of complicated pregnancy].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001378"}
{"pmid": "21001379", "title": "[Vitamin C in the placenta and fetal organs in malaria].", "content": "[Vitamin C in the placenta and fetal organs in malaria].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001379"}
{"pmid": "21001381", "title": "[Clinical course and therapy of genital prolapse in dystrophic women].", "content": "[Clinical course and therapy of genital prolapse in dystrophic women].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001381"}
{"pmid": "21001380", "title": "[Vitamin C content of the ovary and uterus].", "content": "[Vitamin C content of the ovary and uterus].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001380"}
{"pmid": "21001382", "title": "[Retroplacental plasma in uterine hemorrhage].", "content": "[Retroplacental plasma in uterine hemorrhage].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001382"}
{"pmid": "21001383", "title": "[Etiology of galactorrhea].", "content": "[Etiology of galactorrhea].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001383"}
{"pmid": "21001384", "title": "[Paraffinotherapy of chronic and subacute disease of the female genitals].", "content": "[Paraffinotherapy of chronic and subacute disease of the female genitals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001384"}
{"pmid": "21001385", "title": "[Use of \"cold\" mercury quartz lamp in gynecology].", "content": "[Use of \"cold\" mercury quartz lamp in gynecology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001385"}
{"pmid": "21001386", "title": "[Experience with the use of Soviet viscum album in hypertonia].", "content": "[Experience with the use of Soviet viscum album in hypertonia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001386"}
{"pmid": "21001387", "title": "[Use of penicillin in obstetrics and gynecology].", "content": "[Use of penicillin in obstetrics and gynecology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001387"}
{"pmid": "21001388", "title": "[Activities of the Moscow obstetrical-gynecological association during the war].", "content": "[Activities of the Moscow obstetrical-gynecological association during the war].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001388"}
{"pmid": "21001389", "title": "Controversial factors in the management of fundal carcinoma.", "content": "Controversial factors in the management of fundal carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001389"}
{"pmid": "21001390", "title": "A clinical evaluation of ectopic pregnancy.", "content": "A clinical evaluation of ectopic pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001390"}
{"pmid": "21001391", "title": "Endometriosis in association with pregnancy.", "content": "Endometriosis in association with pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001391"}
{"pmid": "21001392", "title": "Manual removal of the placenta; a benign procedure.", "content": "Manual removal of the placenta; a benign procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001392"}
{"pmid": "21001393", "title": "The relationship of maternal weight gain to the weight of the newborn infant.", "content": "The relationship of maternal weight gain to the weight of the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001393"}
{"pmid": "21001394", "title": "Adenomyosis of the uterus; a study of 52 reported cases and a review of the literature.", "content": "Adenomyosis of the uterus; a study of 52 reported cases and a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001394"}
{"pmid": "21001395", "title": "Complications and fetal mortality in 136 cases of multiple pregnancy.", "content": "Complications and fetal mortality in 136 cases of multiple pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001395"}
{"pmid": "21001396", "title": "A report on 2,798 vaginal hysterectomies.", "content": "A report on 2,798 vaginal hysterectomies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001396"}
{"pmid": "21001397", "title": "Arrhenoblastoma of the ovary, with a report of two cases.", "content": "Arrhenoblastoma of the ovary, with a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001397"}
{"pmid": "21001398", "title": "A study of 500 vaginal hysterectomies.", "content": "A study of 500 vaginal hysterectomies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001398"}
{"pmid": "21001399", "title": "An analysis of 257 cases of sterility.", "content": "An analysis of 257 cases of sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001399"}
{"pmid": "21001400", "title": "Saddle block anesthesia with nupercaine in obstetrics.", "content": "Saddle block anesthesia with nupercaine in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001400"}
{"pmid": "21001402", "title": "Psychoneurotic symptoms following hysterectomy.", "content": "Psychoneurotic symptoms following hysterectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001402"}
{"pmid": "21001403", "title": "Respiration during the first hour of life.", "content": "Respiration during the first hour of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001403"}
{"pmid": "21001404", "title": "Early puerperal rising.", "content": "Early puerperal rising.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001404"}
{"pmid": "21001401", "title": "Addition of penicillin sodium to anesthetic agent for local infiltration anesthesia; preliminary report.", "content": "Addition of penicillin sodium to anesthetic agent for local infiltration anesthesia; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001401"}
{"pmid": "21001407", "title": "An unusual case of holoacephalus.", "content": "An unusual case of holoacephalus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001407"}
{"pmid": "21001405", "title": "Relation of early rising to morbidity in cesarean section.", "content": "Relation of early rising to morbidity in cesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001405"}
{"pmid": "21001406", "title": "Composition of the human placenta; lipid content.", "content": "Composition of the human placenta; lipid content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001406"}
{"pmid": "21001408", "title": "The effect of essential hypertension on pregnancy.", "content": "The effect of essential hypertension on pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001408"}
{"pmid": "21001409", "title": "Granulosa-cell tumor of the ovary.", "content": "Granulosa-cell tumor of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001409"}
{"pmid": "21001410", "title": "Lipomas of the broad ligament extending beyond the confines of the pelvis.", "content": "Lipomas of the broad ligament extending beyond the confines of the pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001410"}
{"pmid": "21001411", "title": "Adult Mediterranean anemia complicated by pregnancy.", "content": "Adult Mediterranean anemia complicated by pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001411"}
{"pmid": "21001412", "title": "Pelvic endometriosis as a cause of hydronephrosis.", "content": "Pelvic endometriosis as a cause of hydronephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001412"}
{"pmid": "21001413", "title": "Functional uterine bleeding; a summarizing review.", "content": "Functional uterine bleeding; a summarizing review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001413"}
{"pmid": "21001416", "title": "Machine accounting as a means to better hospital management.", "content": "Machine accounting as a means to better hospital management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001416"}
{"pmid": "21001417", "title": "Could the general hospital use artificial sunshine solarium?", "content": "Could the general hospital use artificial sunshine solarium?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001417"}
{"pmid": "21001418", "title": "A single accrediting body in nursing in relation to the Catholic schools of nursing.", "content": "A single accrediting body in nursing in relation to the Catholic schools of nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001418"}
{"pmid": "21001420", "title": "Recollections of the international health conference.", "content": "Recollections of the international health conference.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001420"}
{"pmid": "21001419", "title": "A guide for the night nurse.", "content": "A guide for the night nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001419"}
{"pmid": "21001422", "title": "Why blame hospitals for the personnel shortage?", "content": "Why blame hospitals for the personnel shortage?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001422"}
{"pmid": "21001421", "title": "When higher pay fails, what else may be done to maintain nursing service?", "content": "When higher pay fails, what else may be done to maintain nursing service?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001421"}
{"pmid": "21001423", "title": "Offices for doctors; Pennsylvania Hospital's modern facilities.", "content": "Offices for doctors; Pennsylvania Hospital's modern facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001423"}
{"pmid": "21001424", "title": "Even the medium-sized hospital should have a fulltime chief of staff.", "content": "Even the medium-sized hospital should have a fulltime chief of staff.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001424"}
{"pmid": "21001425", "title": "Medical social service; the secret is liaison.", "content": "Medical social service; the secret is liaison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001425"}
{"pmid": "21001428", "title": "The intern's welfare; whose responsibility?", "content": "The intern's welfare; whose responsibility?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001428"}
{"pmid": "21001430", "title": "The fund sources change in hospital construction.", "content": "The fund sources change in hospital construction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001430"}
{"pmid": "21001426", "title": "Medical social service criteria for evaluation.", "content": "Medical social service criteria for evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001426"}
{"pmid": "21001427", "title": "An expanded program for better accounting.", "content": "An expanded program for better accounting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001427"}
{"pmid": "21001429", "title": "Narcotics; hospitals' legal and moral responsibilities.", "content": "Narcotics; hospitals' legal and moral responsibilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001429"}
{"pmid": "21001431", "title": "U.N.R.R.A. brings health and hope to the victims of total war.", "content": "U.N.R.R.A. brings health and hope to the victims of total war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001431"}
{"pmid": "21001432", "title": "Anesthesia centennial, or is it?", "content": "Anesthesia centennial, or is it?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001432"}
{"pmid": "21001433", "title": "On the financial side of physical therapy.", "content": "On the financial side of physical therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001433"}
{"pmid": "21001434", "title": "100 beds for tuberculosis.", "content": "100 beds for tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001434"}
{"pmid": "21001435", "title": "Watch dog of the records.", "content": "Watch dog of the records.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001435"}
{"pmid": "21001437", "title": "Equal rights in group practice.", "content": "Equal rights in group practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001437"}
{"pmid": "21001436", "title": "Advice to administrative interns.", "content": "Advice to administrative interns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001436"}
{"pmid": "21001438", "title": "The immunochemistry of toxins and toxoids; the preparation and immunologic evaluation of purified tetanol toxoid.", "content": "The immunochemistry of toxins and toxoids; the preparation and immunologic evaluation of purified tetanol toxoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001438"}
{"pmid": "21001439", "title": "An influenza index on periodic determination of average antibody titers of population samples.", "content": "An influenza index on periodic determination of average antibody titers of population samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001439"}
{"pmid": "21001440", "title": "Reactivation of overneutralized mixtures of influenza virus and antibody.", "content": "Reactivation of overneutralized mixtures of influenza virus and antibody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001440"}
{"pmid": "21001441", "title": "The antigenicity of alkali-treated bovine serum protein.", "content": "The antigenicity of alkali-treated bovine serum protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001441"}
{"pmid": "21001443", "title": "Studies of antipneumococcal serum; changes in complement-fixing activity of rabbit sera during periods of immunization, rest, and reimmunization.", "content": "Studies of antipneumococcal serum; changes in complement-fixing activity of rabbit sera during periods of immunization, rest, and reimmunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001443"}
{"pmid": "21001442", "title": "Standardization of the cardiolipin-lecithin-cholesterol antigen in the complement-fixation test with cerebro-spinal fluid.", "content": "Standardization of the cardiolipin-lecithin-cholesterol antigen in the complement-fixation test with cerebro-spinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001442"}
{"pmid": "21001444", "title": "Studies of anti-pneumococcal serum; complement-fixing activity of fractionated rabbit serum.", "content": "Studies of anti-pneumococcal serum; complement-fixing activity of fractionated rabbit serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001444"}
{"pmid": "21001445", "title": "A coliform bacterium with the complete antigens of Salmonella newington.", "content": "A coliform bacterium with the complete antigens of Salmonella newington.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001445"}
{"pmid": "21001447", "title": "Alterations in pathogenesis of experimental lymphocytic choriomeningitis caused by prepassage of the virus through heterologous host.", "content": "Alterations in pathogenesis of experimental lymphocytic choriomeningitis caused by prepassage of the virus through heterologous host.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001447"}
{"pmid": "21001446", "title": "Attenuation of virulence with retention of antigenicity of mumps virus after passage in the embryonated egg.", "content": "Attenuation of virulence with retention of antigenicity of mumps virus after passage in the embryonated egg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001446"}
{"pmid": "21001448", "title": "Preparation and evaluation of an irradiated toxoid from the toxin of Shigella dysenteriae.", "content": "Preparation and evaluation of an irradiated toxoid from the toxin of Shigella dysenteriae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001448"}
{"pmid": "21001449", "title": "Studies on the reversibility of the antigen-antibody reaction; the disaggregation of agglutinated pneumococci exposed to homologous polysaccharide.", "content": "Studies on the reversibility of the antigen-antibody reaction; the disaggregation of agglutinated pneumococci exposed to homologous polysaccharide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001449"}
{"pmid": "21001450", "title": "A national program for the amputee.", "content": "A national program for the amputee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001450"}
{"pmid": "21001451", "title": "Rehabilitation of the disabled Negro.", "content": "Rehabilitation of the disabled Negro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001451"}
{"pmid": "21001452", "title": "Coordinating our services in vocational rehabilitation; problems and procedures of case findings.", "content": "Coordinating our services in vocational rehabilitation; problems and procedures of case findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001452"}
{"pmid": "21001453", "title": "The approach to providing service to the epileptic.", "content": "The approach to providing service to the epileptic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001453"}
{"pmid": "21001454", "title": "The Grand Rapids Rehabilitation League.", "content": "The Grand Rapids Rehabilitation League.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001454"}
{"pmid": "21001455", "title": "Application of psychiatry to vocational rehabilitation.", "content": "Application of psychiatry to vocational rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001455"}
{"pmid": "21001456", "title": "Rehabilitation of British industry's neurosis cases.", "content": "Rehabilitation of British industry's neurosis cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001456"}
{"pmid": "21001457", "title": "Financing international institutions.", "content": "Financing international institutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001457"}
{"pmid": "21001458", "title": "Levels of blood pressure in both arms and legs in normal subjects and patients suffering from certain diseases.", "content": "Levels of blood pressure in both arms and legs in normal subjects and patients suffering from certain diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001458"}
{"pmid": "21001459", "title": "Relative importance of certain variables in the clinical determination of blood pressure.", "content": "Relative importance of certain variables in the clinical determination of blood pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001459"}
{"pmid": "21001460", "title": "Concentration of renin in renal venous blood in patients with chronic heart failure.", "content": "Concentration of renin in renal venous blood in patients with chronic heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001460"}
{"pmid": "21001461", "title": "Relief of pellagrous glossitis with synthetic folic acid.", "content": "Relief of pellagrous glossitis with synthetic folic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001461"}
{"pmid": "21001462", "title": "Results from subtotal gastric resection in peptic ulcer; the internist's viewpoint.", "content": "Results from subtotal gastric resection in peptic ulcer; the internist's viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001462"}
{"pmid": "21001463", "title": "The nisulfazole treatment of chronic ulcerative colitis.", "content": "The nisulfazole treatment of chronic ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001463"}
{"pmid": "21001464", "title": "Rôle of hyaluronidase in human infertility.", "content": "Rôle of hyaluronidase in human infertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001464"}
{"pmid": "21001465", "title": "Pneumonia; etiology, diagnosis and specific treatment.", "content": "Pneumonia; etiology, diagnosis and specific treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001465"}
{"pmid": "21001466", "title": "Curare; a review of it therapeutic effects and their physiological basis.", "content": "Curare; a review of it therapeutic effects and their physiological basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001466"}
{"pmid": "21001467", "title": "Chemotherapy and antibiotics in the treatment of meningitis.", "content": "Chemotherapy and antibiotics in the treatment of meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001467"}
{"pmid": "21001468", "title": "Treatment of coronary artery disease.", "content": "Treatment of coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001468"}
{"pmid": "21001469", "title": "Purpura, arthritis, hepatomegaly and hepatic failure.", "content": "Purpura, arthritis, hepatomegaly and hepatic failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001469"}
{"pmid": "21001470", "title": "Agranulocytosis occurring after exposure to a D.D.T. pyrethrum aerosol bomb.", "content": "Agranulocytosis occurring after exposure to a D.D.T. pyrethrum aerosol bomb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001470"}
{"pmid": "21001471", "title": "Lupus erythematosus disseminatus in a male.", "content": "Lupus erythematosus disseminatus in a male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001471"}
{"pmid": "21001472", "title": "Purulent pericardial effusion.", "content": "Purulent pericardial effusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001472"}
{"pmid": "21001473", "title": "Direct electrocardiography of the heart during restoration.", "content": "Direct electrocardiography of the heart during restoration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001473"}
{"pmid": "21001474", "title": "A special form of virus neuroinfection in children.", "content": "A special form of virus neuroinfection in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001474"}
{"pmid": "21001475", "title": "Sleep in the treatment of pain.", "content": "Sleep in the treatment of pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001475"}
{"pmid": "21001476", "title": "Causalgia and its treatment.", "content": "Causalgia and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001476"}
{"pmid": "21001477", "title": "Posttraumatic contractures.", "content": "Posttraumatic contractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001477"}
{"pmid": "21001478", "title": "Autonomic disturbances in brain injuries.", "content": "Autonomic disturbances in brain injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001478"}
{"pmid": "21001479", "title": "The pyramidal syndrome.", "content": "The pyramidal syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001479"}
{"pmid": "21001480", "title": "Histology of a nerve graft four months after operation.", "content": "Histology of a nerve graft four months after operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001480"}
{"pmid": "21001481", "title": "Motor chronaxie during blindfolding in nerve trauma.", "content": "Motor chronaxie during blindfolding in nerve trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001481"}
{"pmid": "21001482", "title": "Nervous stimulation and cell chemistry.", "content": "Nervous stimulation and cell chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001482"}
{"pmid": "21001483", "title": "Combined therapy in schizophrenia.", "content": "Combined therapy in schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001483"}
{"pmid": "21001484", "title": "Progress of Russian psychiatry.", "content": "Progress of Russian psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001484"}
{"pmid": "21001485", "title": "Medical aspects of semistravation in Leningrad (siege 1941-1942).", "content": "Medical aspects of semistravation in Leningrad (siege 1941-1942).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001485"}
{"pmid": "21001486", "title": "Chronic abdominal pain.", "content": "Chronic abdominal pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001486"}
{"pmid": "21001488", "title": "Marasmus.", "content": "Marasmus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001488"}
{"pmid": "21001487", "title": "Problem of prolonged pyrexia.", "content": "Problem of prolonged pyrexia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001487"}
{"pmid": "21001489", "title": "Poor eye sight.", "content": "Poor eye sight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001489"}
{"pmid": "21001490", "title": "Health and its relative adjustment to laws of nature.", "content": "Health and its relative adjustment to laws of nature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001490"}
{"pmid": "21001491", "title": "An interesting case of foreign body in the nose.", "content": "An interesting case of foreign body in the nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001491"}
{"pmid": "21001492", "title": "A case note on malignant malaria.", "content": "A case note on malignant malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001492"}
{"pmid": "21001493", "title": "Clinical malaria; a case report.", "content": "Clinical malaria; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001493"}
{"pmid": "21001494", "title": "An unusual persistent secondary port-partum haemostatic viper venom.", "content": "An unusual persistent secondary port-partum haemostatic viper venom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001494"}
{"pmid": "21001495", "title": "Serum-level of penicillin.", "content": "Serum-level of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001495"}
{"pmid": "21001496", "title": "Haemoglobinuria and vitex pedunculosis; a case report.", "content": "Haemoglobinuria and vitex pedunculosis; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001496"}
{"pmid": "21001497", "title": "A man without mouth.", "content": "A man without mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001497"}
{"pmid": "21001498", "title": "A case of cerebrospinal meningitis with lumbar puncture.", "content": "A case of cerebrospinal meningitis with lumbar puncture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001498"}
{"pmid": "21001499", "title": "Medical treatment in acute intestinal obstruction.", "content": "Medical treatment in acute intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001499"}
{"pmid": "21001500", "title": "Leptazol (cardiazol) in psychoneurosis.", "content": "Leptazol (cardiazol) in psychoneurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001500"}
{"pmid": "21001501", "title": "A study of peptic ulcer.", "content": "A study of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001501"}
{"pmid": "21001502", "title": "Breast milk bank in maternity units.", "content": "Breast milk bank in maternity units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001502"}
{"pmid": "21001504", "title": "Facial palsy accompanying acute suppurative otitis media.", "content": "Facial palsy accompanying acute suppurative otitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001504"}
{"pmid": "21001503", "title": "Painful-feet syndrome among prisoners of war in the Far East.", "content": "Painful-feet syndrome among prisoners of war in the Far East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001503"}
{"pmid": "21001505", "title": "Criterion for conservation of the bowel in strangulation.", "content": "Criterion for conservation of the bowel in strangulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001505"}
{"pmid": "21001508", "title": "Medical experiences in Japanese captivity.", "content": "Medical experiences in Japanese captivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001508"}
{"pmid": "21001506", "title": "Vesical calculus complicating procidentia.", "content": "Vesical calculus complicating procidentia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001506"}
{"pmid": "21001509", "title": "Haemoglobin and protein levels and spleen indices in N. Greece; their relation to diet.", "content": "Haemoglobin and protein levels and spleen indices in N. Greece; their relation to diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001509"}
{"pmid": "21001512", "title": "Abacterial pyuria presenting as urethritis.", "content": "Abacterial pyuria presenting as urethritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001512"}
{"pmid": "21001507", "title": "Lice in hospital.", "content": "Lice in hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001507"}
{"pmid": "21001511", "title": "Battle exhaustion.", "content": "Battle exhaustion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001511"}
{"pmid": "21001510", "title": "An investigation into certain tongue changes in British troops.", "content": "An investigation into certain tongue changes in British troops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001510"}
{"pmid": "21001513", "title": "BURGERSPITAL of Basle; a landmark in municipal hospital building.", "content": "BURGERSPITAL of Basle; a landmark in municipal hospital building.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001513"}
{"pmid": "21001514", "title": "JOHANN CHRISTIAN GOTTFRIED JORG [1779-1856] and his experimenting society.", "content": "JOHANN CHRISTIAN GOTTFRIED JORG [1779-1856] and his experimenting society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001514"}
{"pmid": "21001515", "title": "Before and after Morton; historical survey of anesthesia.", "content": "Before and after Morton; historical survey of anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001515"}
{"pmid": "21001516", "title": "Recent advances in anesthesia.", "content": "Recent advances in anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001516"}
{"pmid": "21001517", "title": "Theories of anaesthetic action.", "content": "Theories of anaesthetic action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001517"}
{"pmid": "21001518", "title": "JOHN SNOW, anesthetist and epidemiologist.", "content": "JOHN SNOW, anesthetist and epidemiologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001518"}
{"pmid": "21001519", "title": "The history and development of anaesthetic apparatus.", "content": "The history and development of anaesthetic apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001519"}
{"pmid": "21001520", "title": "Anaesthesia through the eyes of a poet.", "content": "Anaesthesia through the eyes of a poet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001520"}
{"pmid": "21001521", "title": "Insanity with epilepsy following infestation by Cysticercus cellulosae.", "content": "Insanity with epilepsy following infestation by Cysticercus cellulosae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001521"}
{"pmid": "21001522", "title": "Replacing the Irving box; a new suggestion.", "content": "Replacing the Irving box; a new suggestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001522"}
{"pmid": "21001523", "title": "Epidemic gastroenteritis successfully treated with mepacrine.", "content": "Epidemic gastroenteritis successfully treated with mepacrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001523"}
{"pmid": "21001525", "title": "The lymphomatous diseases; functional and pathologic lymph node alterations other than malignant lymphomas.", "content": "The lymphomatous diseases; functional and pathologic lymph node alterations other than malignant lymphomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001525"}
{"pmid": "21001524", "title": "History of the Hogben test.", "content": "History of the Hogben test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001524"}
{"pmid": "21001526", "title": "Tetraethylammonium bromide in peripheral vascular disease and allied disorders; a new method of blocking the autonomic ganglia.", "content": "Tetraethylammonium bromide in peripheral vascular disease and allied disorders; a new method of blocking the autonomic ganglia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001526"}
{"pmid": "21001527", "title": "Carcinoma of the male breast.", "content": "Carcinoma of the male breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001527"}
{"pmid": "21001528", "title": "Embolism of central retinal artery.", "content": "Embolism of central retinal artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001528"}
{"pmid": "21001529", "title": "Great Lakes pioneers in medicine.", "content": "Great Lakes pioneers in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001529"}
{"pmid": "21001530", "title": "Human reactions to experimentally induced impact forces [plane-crash stresses on the human body].", "content": "Human reactions to experimentally induced impact forces [plane-crash stresses on the human body].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001530"}
{"pmid": "21001531", "title": "Dermatologic aspects of dermatitis due to atabrine.", "content": "Dermatologic aspects of dermatitis due to atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001531"}
{"pmid": "21001532", "title": "Atabrine dermatitis and associated aplastic anemia.", "content": "Atabrine dermatitis and associated aplastic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001532"}
{"pmid": "21001533", "title": "Untoward effects of atabrine.", "content": "Untoward effects of atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001533"}
{"pmid": "21001534", "title": "Observations on the function of the clavicle.", "content": "Observations on the function of the clavicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001534"}
{"pmid": "21001535", "title": "Two team abdominoperineal resection.", "content": "Two team abdominoperineal resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001535"}
{"pmid": "21001536", "title": "The responsibility of the pediatrician in the orthodontic problem.", "content": "The responsibility of the pediatrician in the orthodontic problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001536"}
{"pmid": "21001538", "title": "[CASE history: polyarteritis nodosa with massive involvement of the kidney masqueraded as acute glomerular nephritis].", "content": "[CASE history: polyarteritis nodosa with massive involvement of the kidney masqueraded as acute glomerular nephritis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001538"}
{"pmid": "21001537", "title": "Present concepts of the clinical significance of unipolar precordial electrocardiograms.", "content": "Present concepts of the clinical significance of unipolar precordial electrocardiograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001537"}
{"pmid": "21001539", "title": "The treatment of subacute bacterial endocarditis.", "content": "The treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001539"}
{"pmid": "21001540", "title": "The physician and adoption.", "content": "The physician and adoption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001540"}
{"pmid": "21001541", "title": "Ascorbic acid metabolism after trauma in man.", "content": "Ascorbic acid metabolism after trauma in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001541"}
{"pmid": "21001545", "title": "Observations on the sprue syndrome.", "content": "Observations on the sprue syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001545"}
{"pmid": "21001542", "title": "Bilateral frontal lobe leucotomy in the treatment of mental disease.", "content": "Bilateral frontal lobe leucotomy in the treatment of mental disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001542"}
{"pmid": "21001547", "title": "Further studies on ultraviolet radiation in surgery.", "content": "Further studies on ultraviolet radiation in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001547"}
{"pmid": "21001548", "title": "The prognosis in cancer.", "content": "The prognosis in cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001548"}
{"pmid": "21001549", "title": "The role of the emotions in the production of gastro-intestinal disturbances.", "content": "The role of the emotions in the production of gastro-intestinal disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001549"}
{"pmid": "21001550", "title": "The effect of benzedrine on mental or physical fatigue in soldiers.", "content": "The effect of benzedrine on mental or physical fatigue in soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001550"}
{"pmid": "21001551", "title": "Clinical observations on the use of benadryl, a new anti-histamine compound.", "content": "Clinical observations on the use of benadryl, a new anti-histamine compound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001551"}
{"pmid": "21001552", "title": "Vein ligation in the prevention of pulmonary embolus.", "content": "Vein ligation in the prevention of pulmonary embolus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001552"}
{"pmid": "21001553", "title": "The management of emergencies in diabetes mellitus.", "content": "The management of emergencies in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001553"}
{"pmid": "21001558", "title": "Situs inversus.", "content": "Situs inversus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001558"}
{"pmid": "21001557", "title": "Progress report on a case of auricular fibrillation demonstrated in an infant of three months.", "content": "Progress report on a case of auricular fibrillation demonstrated in an infant of three months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001557"}
{"pmid": "21001559", "title": "Physiological considerations of the etiology and treatment of obesity.", "content": "Physiological considerations of the etiology and treatment of obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001559"}
{"pmid": "21001560", "title": "A medical grading code.", "content": "A medical grading code.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001560"}
{"pmid": "21001561", "title": "Trepanation among the early Indians of British Columbia.", "content": "Trepanation among the early Indians of British Columbia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001561"}
{"pmid": "21001562", "title": "The nature and treatment of peptic ulcer.", "content": "The nature and treatment of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001562"}
{"pmid": "21001563", "title": "Allergy associated with asthma dermatitis cataract and optic atrophy treated with urinary proteose; report of a case.", "content": "Allergy associated with asthma dermatitis cataract and optic atrophy treated with urinary proteose; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001563"}
{"pmid": "21001564", "title": "The surgical treatment of gallbladder disease.", "content": "The surgical treatment of gallbladder disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001564"}
{"pmid": "21001565", "title": "[Myocardial and endocardial fibrosis with cardiac failure].", "content": "[Myocardial and endocardial fibrosis with cardiac failure].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001565"}
{"pmid": "21001566", "title": "Birth in relation to foetal development.", "content": "Birth in relation to foetal development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001566"}
{"pmid": "21001567", "title": "Bacteriological investigation of an outbreak of food poisoning.", "content": "Bacteriological investigation of an outbreak of food poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001567"}
{"pmid": "21001568", "title": "Studies in the mechanics of synovial joints; hinge-joints and the nature of intra-articular displacements.", "content": "Studies in the mechanics of synovial joints; hinge-joints and the nature of intra-articular displacements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001568"}
{"pmid": "21001569", "title": "Blood transfusion; blood grouping.", "content": "Blood transfusion; blood grouping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001569"}
{"pmid": "21001570", "title": "Supernumerary pollex.", "content": "Supernumerary pollex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001570"}
{"pmid": "21001572", "title": "Surgical anaesthesia.", "content": "Surgical anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001572"}
{"pmid": "21001571", "title": "A pressure bottle for use in celloidin-corrosion and other injection work.", "content": "A pressure bottle for use in celloidin-corrosion and other injection work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001571"}
{"pmid": "21001573", "title": "The introduction of ether and chloroform to Dublin.", "content": "The introduction of ether and chloroform to Dublin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001573"}
{"pmid": "21001574", "title": "Anaesthetic fatalities.", "content": "Anaesthetic fatalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001574"}
{"pmid": "21001575", "title": "The status of the anaesthetist.", "content": "The status of the anaesthetist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001575"}
{"pmid": "21001576", "title": "Anaesthesia in abdominal surgery.", "content": "Anaesthesia in abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001576"}
{"pmid": "21001577", "title": "Anaesthesia in thoracic surgery.", "content": "Anaesthesia in thoracic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001577"}
{"pmid": "21001578", "title": "Anaesthesia in neurosurgery.", "content": "Anaesthesia in neurosurgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001578"}
{"pmid": "21001579", "title": "Anaesthesia in goitre operations.", "content": "Anaesthesia in goitre operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001579"}
{"pmid": "21001580", "title": "Anaesthesia in childhood.", "content": "Anaesthesia in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001580"}
{"pmid": "21001581", "title": "Intravenous anaesthesia.", "content": "Intravenous anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001581"}
{"pmid": "21001582", "title": "Spinal anaesthesia with hypobaric percaine.", "content": "Spinal anaesthesia with hypobaric percaine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001582"}
{"pmid": "21001583", "title": "Cyclopropane anaesthesia.", "content": "Cyclopropane anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001583"}
{"pmid": "21001584", "title": "Trichlorethylene anaesthesia.", "content": "Trichlorethylene anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001584"}
{"pmid": "21001585", "title": "Viral infections of respiratory tract; their treatment and prevention.", "content": "Viral infections of respiratory tract; their treatment and prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001585"}
{"pmid": "21001586", "title": "Leukoplakia (leukokeratosis) of the palate, papular form; its relation to the use of tobacco.", "content": "Leukoplakia (leukokeratosis) of the palate, papular form; its relation to the use of tobacco.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001586"}
{"pmid": "21001587", "title": "Management of patients with chronic headache.", "content": "Management of patients with chronic headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001587"}
{"pmid": "21001588", "title": "Insulin in the treatment of diabetes mellitus.", "content": "Insulin in the treatment of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001588"}
{"pmid": "21001589", "title": "The role of DDT in controlling insect-borne diseases of man.", "content": "The role of DDT in controlling insect-borne diseases of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001589"}
{"pmid": "21001590", "title": "Porphyria with epidermolysis bullosa; report of a case of the tardive congenital type with demonstration of latent porphyria in a sister of the patient.", "content": "Porphyria with epidermolysis bullosa; report of a case of the tardive congenital type with demonstration of latent porphyria in a sister of the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001590"}
{"pmid": "21001591", "title": "Meningitis due to Escherichia coli; streptomycin therapy.", "content": "Meningitis due to Escherichia coli; streptomycin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001591"}
{"pmid": "21001592", "title": "DENTAL practice acts; validity of restrictions on advertising [Washington, D. C.].", "content": "DENTAL practice acts; validity of restrictions on advertising [Washington, D. C.].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001592"}
{"pmid": "21001593", "title": "Pharmacologic basis of cardiac therapy.", "content": "Pharmacologic basis of cardiac therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001593"}
{"pmid": "21001594", "title": "Modern concept of the neuroses.", "content": "Modern concept of the neuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001594"}
{"pmid": "21001595", "title": "Recognition and treatment of early vitamin deficiency states.", "content": "Recognition and treatment of early vitamin deficiency states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001595"}
{"pmid": "21001596", "title": "Complications of intrathecal use of penicillin.", "content": "Complications of intrathecal use of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001596"}
{"pmid": "21001597", "title": "The relationship of physical medicine to general practice.", "content": "The relationship of physical medicine to general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001597"}
{"pmid": "21001598", "title": "Canities and alopecia in children associated with avitaminosis; preliminary report.", "content": "Canities and alopecia in children associated with avitaminosis; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001598"}
{"pmid": "21001600", "title": "Diffuse calcification of the pancreas.", "content": "Diffuse calcification of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001600"}
{"pmid": "21001599", "title": "The control of bleeding during operation by induced hypotension.", "content": "The control of bleeding during operation by induced hypotension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001599"}
{"pmid": "21001601", "title": "Cylindroma; report of an unusually extensive case.", "content": "Cylindroma; report of an unusually extensive case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001601"}
{"pmid": "21001602", "title": "Maternal welfare and the Negro.", "content": "Maternal welfare and the Negro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001602"}
{"pmid": "21001603", "title": "Present status of gelatin sponge for the control of hemorrhage; with experimental data on its use for wounds of the great vessels and the heart.", "content": "Present status of gelatin sponge for the control of hemorrhage; with experimental data on its use for wounds of the great vessels and the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001603"}
{"pmid": "21001604", "title": "Sympathectomy for reflex sympathetic dystrophy; report of twenty-nine cases.", "content": "Sympathectomy for reflex sympathetic dystrophy; report of twenty-nine cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001604"}
{"pmid": "21001605", "title": "The malaria problem today; influence of wartime experience and research.", "content": "The malaria problem today; influence of wartime experience and research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001605"}
{"pmid": "21001606", "title": "Anastomosis of the aorta to a pulmonary artery; certain types in congenital heart disease.", "content": "Anastomosis of the aorta to a pulmonary artery; certain types in congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001606"}
{"pmid": "21001608", "title": "Streptomycin therapy in infection of urinary tract; failure because of development of resistance.", "content": "Streptomycin therapy in infection of urinary tract; failure because of development of resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001608"}
{"pmid": "21001607", "title": "Cerebrospinal cryptococcosis.", "content": "Cerebrospinal cryptococcosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001607"}
{"pmid": "21001609", "title": "History of the American Medical Association.", "content": "History of the American Medical Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001609"}
{"pmid": "21001610", "title": "Acute infectious lymphocytosis in an adult; review of literature and report of case.", "content": "Acute infectious lymphocytosis in an adult; review of literature and report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001610"}
{"pmid": "21001611", "title": "Progeria with nanism and congenital cataracts in a five year old child.", "content": "Progeria with nanism and congenital cataracts in a five year old child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001611"}
{"pmid": "21001612", "title": "The use of paying patients in clinical research and teaching.", "content": "The use of paying patients in clinical research and teaching.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001612"}
{"pmid": "21001613", "title": "The National Institute for Medical Research.", "content": "The National Institute for Medical Research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001613"}
{"pmid": "21001614", "title": "A method of displaying anatomical pictures.", "content": "A method of displaying anatomical pictures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001614"}
{"pmid": "21001615", "title": "Undergraduate education in allergy; report of the Subcommittee on Undergraduate Education in Allergy of the American Academy of Allergy.", "content": "Undergraduate education in allergy; report of the Subcommittee on Undergraduate Education in Allergy of the American Academy of Allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001615"}
{"pmid": "21001616", "title": "Has Alpha Omega Alpha a function?", "content": "Has Alpha Omega Alpha a function?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001616"}
{"pmid": "21001617", "title": "A practitioner's reaction to trends in medical education.", "content": "A practitioner's reaction to trends in medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001617"}
{"pmid": "21001618", "title": "The practice of neurology in the United States of America.", "content": "The practice of neurology in the United States of America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001618"}
{"pmid": "21001619", "title": "The doctrine of mutual aid.", "content": "The doctrine of mutual aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001619"}
{"pmid": "21001620", "title": "Clinical uses of 2,2-dimercaptopropanol (BAL); the systemic treatment of experimental arsenic poisoning (mapharsen, lewisite, phenyl arsenoxide) with BAL.", "content": "Clinical uses of 2,2-dimercaptopropanol (BAL); the systemic treatment of experimental arsenic poisoning (mapharsen, lewisite, phenyl arsenoxide) with BAL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001620"}
{"pmid": "21001621", "title": "Clinical uses of 2,3-dimercaptropropanol (BAL); the effect of BAL on the excretion of arsenic in normal subjects and after minimal exposure to arsenical smoke.", "content": "Clinical uses of 2,3-dimercaptropropanol (BAL); the effect of BAL on the excretion of arsenic in normal subjects and after minimal exposure to arsenical smoke.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001621"}
{"pmid": "21001622", "title": "Clinical uses of 2,3-dimercaptopropanol (BAL); studies on the toxicity of BAL on percutaneous and parenteral administration.", "content": "Clinical uses of 2,3-dimercaptopropanol (BAL); studies on the toxicity of BAL on percutaneous and parenteral administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001622"}
{"pmid": "21001623", "title": "Clinical uses of 2,3-dimercaptopropanol (BAL); pharmacologic observations on BAL by intramuscular injection in man.", "content": "Clinical uses of 2,3-dimercaptopropanol (BAL); pharmacologic observations on BAL by intramuscular injection in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001623"}
{"pmid": "21001624", "title": "Clinical uses of 2,3-dimercaptopropanol (BAL); skin sensitization to BAL.", "content": "Clinical uses of 2,3-dimercaptopropanol (BAL); skin sensitization to BAL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001624"}
{"pmid": "21001625", "title": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of complications of arseno-therapy with BAL (British anti-lewisite).", "content": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of complications of arseno-therapy with BAL (British anti-lewisite).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001625"}
{"pmid": "21001626", "title": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of arsenical dermatitis with preparations of BAL.", "content": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of arsenical dermatitis with preparations of BAL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001626"}
{"pmid": "21001627", "title": "Clinical uses of 2,3-dimercaptopropanol (BAL); the effect of BAL on the excretion of arsenic in arsenical intoxication.", "content": "Clinical uses of 2,3-dimercaptopropanol (BAL); the effect of BAL on the excretion of arsenic in arsenical intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001627"}
{"pmid": "21001628", "title": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of lewisite burns of the eye with BAL.", "content": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of lewisite burns of the eye with BAL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001628"}
{"pmid": "21001629", "title": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of acute systemic mercury poisoning in experimental animals with BAL, thiosorbitol and BAL glucoside.", "content": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of acute systemic mercury poisoning in experimental animals with BAL, thiosorbitol and BAL glucoside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001629"}
{"pmid": "21001630", "title": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of acute mercury poisoning by BAL.", "content": "Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of acute mercury poisoning by BAL.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001630"}
{"pmid": "21001633", "title": "Changes in blood coagulation following coronary thrombosis measured by the heparin retarded clotting test (Waugh and Ruddick test).", "content": "Changes in blood coagulation following coronary thrombosis measured by the heparin retarded clotting test (Waugh and Ruddick test).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001633"}
{"pmid": "21001635", "title": "The use of two radioactive isotopes of iron in tracer studies of erythrocytes.", "content": "The use of two radioactive isotopes of iron in tracer studies of erythrocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001635"}
{"pmid": "21001636", "title": "The measurement of the circulating red cell volume by means of two radioactive isotopes of iron.", "content": "The measurement of the circulating red cell volume by means of two radioactive isotopes of iron.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001636"}
{"pmid": "21001638", "title": "Recording of right heart pressures in normal subjects and in patients with chronic pulmonary disease and various types of cardio-circulatory disease.", "content": "Recording of right heart pressures in normal subjects and in patients with chronic pulmonary disease and various types of cardio-circulatory disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001638"}
{"pmid": "21001639", "title": "War wounds of the abdomen.", "content": "War wounds of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001639"}
{"pmid": "21001640", "title": "Gelsemium in the preparalytic stage of poliomyelitis.", "content": "Gelsemium in the preparalytic stage of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001640"}
{"pmid": "21001641", "title": "Streptococcic pneumonia.", "content": "Streptococcic pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001641"}
{"pmid": "21001642", "title": "Primary atypical pneumonia.", "content": "Primary atypical pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001642"}
{"pmid": "21001643", "title": "Roentgenological aspects of primary atypical pneumonia.", "content": "Roentgenological aspects of primary atypical pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001643"}
{"pmid": "21001644", "title": "BOTULISM in Iowa and United States.", "content": "BOTULISM in Iowa and United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001644"}
{"pmid": "21001645", "title": "Medical history of Dickinson County.", "content": "Medical history of Dickinson County.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001645"}
{"pmid": "21001646", "title": "Demonstration of Rh antibodies in the newborn and further evidence of the pathogenesis of erythroblastosis.", "content": "Demonstration of Rh antibodies in the newborn and further evidence of the pathogenesis of erythroblastosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001646"}
{"pmid": "21001647", "title": "Blood transfusion studies; the differentiation of hemolytic and nonhemolytic transfusion reactions.", "content": "Blood transfusion studies; the differentiation of hemolytic and nonhemolytic transfusion reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001647"}
{"pmid": "21001648", "title": "Blood transfusi studies; the survival of fresh and stored transfused erythrocytes as determined by urobilinogen excretion.", "content": "Blood transfusi studies; the survival of fresh and stored transfused erythrocytes as determined by urobilinogen excretion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001648"}
{"pmid": "21001649", "title": "Blood and bone marrow in infectious mononucleosis; a review of the literature and a report of twenty-five cases.", "content": "Blood and bone marrow in infectious mononucleosis; a review of the literature and a report of twenty-five cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001649"}
{"pmid": "21001651", "title": "Secondary Bacilus pyocyaneus infection in meningitis following intrathecal penicillin therapy.", "content": "Secondary Bacilus pyocyaneus infection in meningitis following intrathecal penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001651"}
{"pmid": "21001650", "title": "Preservatives for syphilis serum with special reference to the use of merthiolate.", "content": "Preservatives for syphilis serum with special reference to the use of merthiolate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001650"}
{"pmid": "21001652", "title": "The two dose dextrose tolerance test in the diagnosis of diabetes mellitus.", "content": "The two dose dextrose tolerance test in the diagnosis of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001652"}
{"pmid": "21001653", "title": "A detailed report on the weights and weight losses of twenty-four men in Santo Tomas Internment Camp.", "content": "A detailed report on the weights and weight losses of twenty-four men in Santo Tomas Internment Camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001653"}
{"pmid": "21001654", "title": "The comparative efficiency of various liver function tests in detecting hepatic damage produced in dogs by xylidine.", "content": "The comparative efficiency of various liver function tests in detecting hepatic damage produced in dogs by xylidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001654"}
{"pmid": "21001655", "title": "Study of absorption from crystalline insulin pellets and solutions at various sites in rabbits.", "content": "Study of absorption from crystalline insulin pellets and solutions at various sites in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001655"}
{"pmid": "21001656", "title": "The nature of the action of dimethylaminoethyl benzhydryl ether hydrochloride (benadryl); effects upon the human eye.", "content": "The nature of the action of dimethylaminoethyl benzhydryl ether hydrochloride (benadryl); effects upon the human eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001656"}
{"pmid": "21001657", "title": "Constant flow gassing chambers; principles influencing design and operation.", "content": "Constant flow gassing chambers; principles influencing design and operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001657"}
{"pmid": "21001658", "title": "The simple estimation of blood ketones in diabetic acidosis.", "content": "The simple estimation of blood ketones in diabetic acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001658"}
{"pmid": "21001659", "title": "War psychiatry and its influence upon postwar psychiatry and upon civilization.", "content": "War psychiatry and its influence upon postwar psychiatry and upon civilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001659"}
{"pmid": "21001660", "title": "What do we know of multiple sclerosis?", "content": "What do we know of multiple sclerosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001660"}
{"pmid": "21001661", "title": "The brain changes associated with electrical shock treatment; a critical review.", "content": "The brain changes associated with electrical shock treatment; a critical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001661"}
{"pmid": "21001662", "title": "A note on the development of speech patterns.", "content": "A note on the development of speech patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001662"}
{"pmid": "21001663", "title": "Neuritis ossificans with osteogenic sarcoma in brachial plexus following trauma; report of case.", "content": "Neuritis ossificans with osteogenic sarcoma in brachial plexus following trauma; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001663"}
{"pmid": "21001664", "title": "The psychiatrist looks at family life.", "content": "The psychiatrist looks at family life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001664"}
{"pmid": "21001665", "title": "Endogenous toxic encephalitis.", "content": "Endogenous toxic encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001665"}
{"pmid": "21001666", "title": "Occlusions of arteries supplying the brain-stem and cerebellum.", "content": "Occlusions of arteries supplying the brain-stem and cerebellum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001666"}
{"pmid": "21001667", "title": "Psychiatric care in hospitals.", "content": "Psychiatric care in hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001667"}
{"pmid": "21001668", "title": "Huntington's chorea in relation to the heredity of personality disorders.", "content": "Huntington's chorea in relation to the heredity of personality disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001668"}
{"pmid": "21001669", "title": "Alabama postwar planning; volunteer prepayment insurance.", "content": "Alabama postwar planning; volunteer prepayment insurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001669"}
{"pmid": "21001670", "title": "Alabama postwar planning; Alabama hospitals.", "content": "Alabama postwar planning; Alabama hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001670"}
{"pmid": "21001671", "title": "The role of the Medical College of Alabama in Alabama medicine.", "content": "The role of the Medical College of Alabama in Alabama medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001671"}
{"pmid": "21001672", "title": "The application of the Rh factor in general practice.", "content": "The application of the Rh factor in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001672"}
{"pmid": "21001673", "title": "CANCER program in New Jersey.", "content": "CANCER program in New Jersey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001673"}
{"pmid": "21001675", "title": "Newer knowledge of malaria.", "content": "Newer knowledge of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001675"}
{"pmid": "21001674", "title": "Diabetes in children.", "content": "Diabetes in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001674"}
{"pmid": "21001676", "title": "The occlusion dressing in the treatment of dermatoses.", "content": "The occlusion dressing in the treatment of dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001676"}
{"pmid": "21001677", "title": "Premature labor.", "content": "Premature labor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001677"}
{"pmid": "21001678", "title": "Protein hydrolysate ointment.", "content": "Protein hydrolysate ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001678"}
{"pmid": "21001680", "title": "The use of oxygen by the general practitioner.", "content": "The use of oxygen by the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001680"}
{"pmid": "21001679", "title": "Progress in reorganization of medical services in the Veterans Administration.", "content": "Progress in reorganization of medical services in the Veterans Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001679"}
{"pmid": "21001681", "title": "Esophageal hiatus hernia.", "content": "Esophageal hiatus hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001681"}
{"pmid": "21001682", "title": "Group practice; an answer to state medicine.", "content": "Group practice; an answer to state medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001682"}
{"pmid": "21001683", "title": "Treatment of carcinoma of the rectum.", "content": "Treatment of carcinoma of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001683"}
{"pmid": "21001684", "title": "Case reports of dissecting aneurysm.", "content": "Case reports of dissecting aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001684"}
{"pmid": "21001685", "title": "The treatment of subacute bacterial endocarditis with penicillin; with emphasis on present-day conclusions; a case report of the disease successfully arrested by massive doses of penicillin.", "content": "The treatment of subacute bacterial endocarditis with penicillin; with emphasis on present-day conclusions; a case report of the disease successfully arrested by massive doses of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001685"}
{"pmid": "21001686", "title": "Protecting the people of Michigan from tuberculosis.", "content": "Protecting the people of Michigan from tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001686"}
{"pmid": "21001687", "title": "Hansen's disease.", "content": "Hansen's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001687"}
{"pmid": "21001688", "title": "Experiences in blood banking in Europe and their application to civilian practice.", "content": "Experiences in blood banking in Europe and their application to civilian practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001688"}
{"pmid": "21001689", "title": "The clinical significance of the Rh factor.", "content": "The clinical significance of the Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001689"}
{"pmid": "21001690", "title": "Recent observations on anemia in scurvy.", "content": "Recent observations on anemia in scurvy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001690"}
{"pmid": "21001691", "title": "Auditory impairment in returned service personnel.", "content": "Auditory impairment in returned service personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001691"}
{"pmid": "21001692", "title": "Rehabilitation of the tuberculous.", "content": "Rehabilitation of the tuberculous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001692"}
{"pmid": "21001693", "title": "Some common proctologic conditions of childhood.", "content": "Some common proctologic conditions of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001693"}
{"pmid": "21001694", "title": "The medical treatment of gall bladder disease.", "content": "The medical treatment of gall bladder disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001694"}
{"pmid": "21001695", "title": "The public health, the politician, and the doctor.", "content": "The public health, the politician, and the doctor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001695"}
{"pmid": "21001696", "title": "Carcinoma of the rectum and rectosigmoid.", "content": "Carcinoma of the rectum and rectosigmoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001696"}
{"pmid": "21001697", "title": "Bronchoscopy; its indications and value; review of 425 consecutive cases.", "content": "Bronchoscopy; its indications and value; review of 425 consecutive cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001697"}
{"pmid": "21001698", "title": "Sympathetic control of blood-vessels of human skeletal muscle.", "content": "Sympathetic control of blood-vessels of human skeletal muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001698"}
{"pmid": "21001699", "title": "Psychoneuroses treated with electrical convulsions; the intensive method.", "content": "Psychoneuroses treated with electrical convulsions; the intensive method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001699"}
{"pmid": "21001700", "title": "Effect of temperature on sedimentation-rate.", "content": "Effect of temperature on sedimentation-rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001700"}
{"pmid": "21001702", "title": "The uses of plastics in surgery.", "content": "The uses of plastics in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001702"}
{"pmid": "21001701", "title": "Treatment of yaws with penicillin.", "content": "Treatment of yaws with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001701"}
{"pmid": "21001703", "title": "Needle and cannula for chest exploration.", "content": "Needle and cannula for chest exploration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001703"}
{"pmid": "21001704", "title": "Tuberculosis in Poland.", "content": "Tuberculosis in Poland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001704"}
{"pmid": "21001705", "title": "INSANITY moral or legal [Heath case].", "content": "INSANITY moral or legal [Heath case].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001705"}
{"pmid": "21001706", "title": "Carcinoma of prostate treated with oestrogens.", "content": "Carcinoma of prostate treated with oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001706"}
{"pmid": "21001707", "title": "Diagnosis of schistosomiasis; intradermal test using a cercarial antigen.", "content": "Diagnosis of schistosomiasis; intradermal test using a cercarial antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001707"}
{"pmid": "21001708", "title": "Penicillin in infancy and childhood.", "content": "Penicillin in infancy and childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001708"}
{"pmid": "21001709", "title": "Observations on fibrinolysis; plasminogen, plasmin, and antiplasmin content of human blood.", "content": "Observations on fibrinolysis; plasminogen, plasmin, and antiplasmin content of human blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001709"}
{"pmid": "21001710", "title": "Exercise and cardiac hypertrophy.", "content": "Exercise and cardiac hypertrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001710"}
{"pmid": "21001711", "title": "ALLEGED cruelty to cats [trial of Dr. E. G. Liddell].", "content": "ALLEGED cruelty to cats [trial of Dr. E. G. Liddell].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001711"}
{"pmid": "21001712", "title": "Clinical experience with streptomycin.", "content": "Clinical experience with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001712"}
{"pmid": "21001713", "title": "Postwar tropical diseases in the United States.", "content": "Postwar tropical diseases in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001713"}
{"pmid": "21001714", "title": "Virus disease from the clinical point of view.", "content": "Virus disease from the clinical point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001714"}
{"pmid": "21001715", "title": "The treatment of infectious hepatitis (catarrhal jaundice).", "content": "The treatment of infectious hepatitis (catarrhal jaundice).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001715"}
{"pmid": "21001716", "title": "The emergency treatment of myasthenia gravis.", "content": "The emergency treatment of myasthenia gravis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001716"}
{"pmid": "21001717", "title": "The diagnosis and treatment of anemia.", "content": "The diagnosis and treatment of anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001717"}
{"pmid": "21001718", "title": "Coronary occlusion.", "content": "Coronary occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001718"}
{"pmid": "21001719", "title": "Diagnosis and treatment of thrombo-embolic disease.", "content": "Diagnosis and treatment of thrombo-embolic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001719"}
{"pmid": "21001720", "title": "Essential hypertension; present status of the problem.", "content": "Essential hypertension; present status of the problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001720"}
{"pmid": "21001721", "title": "Medical aspects of renal insufficiency in urologic practice.", "content": "Medical aspects of renal insufficiency in urologic practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001721"}
{"pmid": "21001722", "title": "Psychogenic or hypothalamic amenorrhea.", "content": "Psychogenic or hypothalamic amenorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001722"}
{"pmid": "21001723", "title": "Diabetic coma and hyperglycemic stupor compared.", "content": "Diabetic coma and hyperglycemic stupor compared.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001723"}
{"pmid": "21001724", "title": "Common sense in allergy; relation to specific treatment.", "content": "Common sense in allergy; relation to specific treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001724"}
{"pmid": "21001725", "title": "Clinical appraisal of demerol, benadryl and pyribenzamine.", "content": "Clinical appraisal of demerol, benadryl and pyribenzamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001725"}
{"pmid": "21001726", "title": "Chemotherapy in diseases of ear, nose and throat.", "content": "Chemotherapy in diseases of ear, nose and throat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001726"}
{"pmid": "21001727", "title": "Diseases of the lungs; differential diagnosis and treatment.", "content": "Diseases of the lungs; differential diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001727"}
{"pmid": "21001728", "title": "Office laboratory tests; technic and interpretation.", "content": "Office laboratory tests; technic and interpretation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001728"}
{"pmid": "21001729", "title": "Pulmonary tuberculosis, bilateral, with cavitation of the right upper lobe, and bronchostenosis.", "content": "Pulmonary tuberculosis, bilateral, with cavitation of the right upper lobe, and bronchostenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001729"}
{"pmid": "21001730", "title": "Obesity as a manifestation of neurosis.", "content": "Obesity as a manifestation of neurosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001730"}
{"pmid": "21001731", "title": "Cardiovascular and respiratory manifestations of neurocirculatory asthenia; pathogenesis and therapy.", "content": "Cardiovascular and respiratory manifestations of neurocirculatory asthenia; pathogenesis and therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001731"}
{"pmid": "21001732", "title": "Singapore and after; a brief historical survey of the activities of the Australian Army Medical Corps in Malaya.", "content": "Singapore and after; a brief historical survey of the activities of the Australian Army Medical Corps in Malaya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001732"}
{"pmid": "21001733", "title": "Administrative and clinical problems in Australian and British prisoner-of-war camps in Singapore, 1942-1945.", "content": "Administrative and clinical problems in Australian and British prisoner-of-war camps in Singapore, 1942-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001733"}
{"pmid": "21001734", "title": "Prisoner-of-war camps in Borneo.", "content": "Prisoner-of-war camps in Borneo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001734"}
{"pmid": "21001735", "title": "Some aspects of protein metabolism in infants and children.", "content": "Some aspects of protein metabolism in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001735"}
{"pmid": "21001736", "title": "The constitution and policies of the Federal Council.", "content": "The constitution and policies of the Federal Council.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001736"}
{"pmid": "21001737", "title": "A case of hydatid disease of the thyroid gland.", "content": "A case of hydatid disease of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001737"}
{"pmid": "21001738", "title": "Spontaneous rupture of the spleen during a malarial rigor.", "content": "Spontaneous rupture of the spleen during a malarial rigor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001738"}
{"pmid": "21001739", "title": "Hypoglycaemic coma due to accidental intravenous administration of protamine zinc insulin.", "content": "Hypoglycaemic coma due to accidental intravenous administration of protamine zinc insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001739"}
{"pmid": "21001740", "title": "Placenta praevia.", "content": "Placenta praevia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001740"}
{"pmid": "21001741", "title": "The use of x rays in obstetrics; plus a presentation of some medicolegal aspects.", "content": "The use of x rays in obstetrics; plus a presentation of some medicolegal aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001741"}
{"pmid": "21001742", "title": "Notes on cancer.", "content": "Notes on cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001742"}
{"pmid": "21001743", "title": "Importance of case history in allergic diseases.", "content": "Importance of case history in allergic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001743"}
{"pmid": "21001744", "title": "Leucorrhea; a diagnostic aid.", "content": "Leucorrhea; a diagnostic aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001744"}
{"pmid": "21001745", "title": "Cancer education.", "content": "Cancer education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001745"}
{"pmid": "21001746", "title": "The gift of speech and the brain.", "content": "The gift of speech and the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001746"}
{"pmid": "21001747", "title": "A placenta acreta.", "content": "A placenta acreta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001747"}
{"pmid": "21001748", "title": "The centenary of the demonstration of ether anesthesia.", "content": "The centenary of the demonstration of ether anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001748"}
{"pmid": "21001749", "title": "A brief survey of prostatic surgery.", "content": "A brief survey of prostatic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001749"}
{"pmid": "21001750", "title": "Double and accessory urethra.", "content": "Double and accessory urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001750"}
{"pmid": "21001751", "title": "Some experiences in the treatment of chronic suppurative otitis media.", "content": "Some experiences in the treatment of chronic suppurative otitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001751"}
{"pmid": "21001753", "title": "Intrapleural penicillin therapy in tuberculosis and mixed infection empyema.", "content": "Intrapleural penicillin therapy in tuberculosis and mixed infection empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001753"}
{"pmid": "21001752", "title": "Intra-ocular malignant melanomas of the choroid; report of three cases.", "content": "Intra-ocular malignant melanomas of the choroid; report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001752"}
{"pmid": "21001754", "title": "Development of a program of health service in industry.", "content": "Development of a program of health service in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001754"}
{"pmid": "21001755", "title": "Diffuse myxoma of lower extremity with elephantiasis.", "content": "Diffuse myxoma of lower extremity with elephantiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001755"}
{"pmid": "21001756", "title": "Normal appendices in 1,000 appendectomies.", "content": "Normal appendices in 1,000 appendectomies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001756"}
{"pmid": "21001757", "title": "Appendicitis; personal experiences.", "content": "Appendicitis; personal experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001757"}
{"pmid": "21001758", "title": "An artificial sphincter; a new operation and device for control of urinary incontinence and nocturnal enuresis.", "content": "An artificial sphincter; a new operation and device for control of urinary incontinence and nocturnal enuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001758"}
{"pmid": "21001759", "title": "Fibroma of the stomach; case report.", "content": "Fibroma of the stomach; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001759"}
{"pmid": "21001760", "title": "Surgical treatment of gallbladder disease; report of 561 consecutive cases at Fairview Hospital.", "content": "Surgical treatment of gallbladder disease; report of 561 consecutive cases at Fairview Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001760"}
{"pmid": "21001761", "title": "Acute hemorrhagic pancreatitis; report of a case.", "content": "Acute hemorrhagic pancreatitis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001761"}
{"pmid": "21001762", "title": "Volvulus of the stomach; report of a case.", "content": "Volvulus of the stomach; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001762"}
{"pmid": "21001763", "title": "A modified Halsted bulkhead rectal anastomosis for use in resection of cancers of the rectosigmoid and upper rectum; inaugural thesis.", "content": "A modified Halsted bulkhead rectal anastomosis for use in resection of cancers of the rectosigmoid and upper rectum; inaugural thesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001763"}
{"pmid": "21001764", "title": "Diabetes mellitus, the neglected disease.", "content": "Diabetes mellitus, the neglected disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001764"}
{"pmid": "21001765", "title": "A consideration of the toxemias of late pregnancy and nutrition.", "content": "A consideration of the toxemias of late pregnancy and nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001765"}
{"pmid": "21001766", "title": "Evisceration following the use of cotton.", "content": "Evisceration following the use of cotton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001766"}
{"pmid": "21001767", "title": "A postwar program for the control of venereal disease.", "content": "A postwar program for the control of venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001767"}
{"pmid": "21001768", "title": "Recent public health trends in dentistry.", "content": "Recent public health trends in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001768"}
{"pmid": "21001769", "title": "Scleredema: a systemic disease.", "content": "Scleredema: a systemic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001769"}
{"pmid": "21001770", "title": "Some unusual findings in an epidemic of anterior poliomyelitis.", "content": "Some unusual findings in an epidemic of anterior poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001770"}
{"pmid": "21001771", "title": "Tetanus, with death due to aseptic dural sinus thrombosis; report of a case.", "content": "Tetanus, with death due to aseptic dural sinus thrombosis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001771"}
{"pmid": "21001772", "title": "Pulmonary tuberculosis.", "content": "Pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001772"}
{"pmid": "21001773", "title": "Epidermoid carcinoma of bronchus (Grade III).", "content": "Epidermoid carcinoma of bronchus (Grade III).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001773"}
{"pmid": "21001774", "title": "Bronchiectasis of left lower lobe.", "content": "Bronchiectasis of left lower lobe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001774"}
{"pmid": "21001775", "title": "Islet-cell tumor of the pancreas with hyperinsulinism; a report of six cases.", "content": "Islet-cell tumor of the pancreas with hyperinsulinism; a report of six cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001775"}
{"pmid": "21001776", "title": "Unrecognized vesical-neck obstruction in women.", "content": "Unrecognized vesical-neck obstruction in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001776"}
{"pmid": "21001777", "title": "Retroperitoneal hemorrhage complicating pregnancy; report of a case.", "content": "Retroperitoneal hemorrhage complicating pregnancy; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001777"}
{"pmid": "21001778", "title": "The effect of age on the clinical effectiveness of nitroglycerin tablets.", "content": "The effect of age on the clinical effectiveness of nitroglycerin tablets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001778"}
{"pmid": "21001779", "title": "The diagnosis of cancer of the pancreas.", "content": "The diagnosis of cancer of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001779"}
{"pmid": "21001780", "title": "[Syphilitic aortitis, with aortic insufficiency].", "content": "[Syphilitic aortitis, with aortic insufficiency].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001780"}
{"pmid": "21001781", "title": "[Chondroma of eighth costal cartilage].", "content": "[Chondroma of eighth costal cartilage].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001781"}
{"pmid": "21001782", "title": "Endometriosis; two hundred cases considered from the viewpoint of the practitioner.", "content": "Endometriosis; two hundred cases considered from the viewpoint of the practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001782"}
{"pmid": "21001783", "title": "Bright's disease; clinical manifestations in relation to etiology and prognosis.", "content": "Bright's disease; clinical manifestations in relation to etiology and prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001783"}
{"pmid": "21001784", "title": "Hepatic complications of amebiasis.", "content": "Hepatic complications of amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001784"}
{"pmid": "21001785", "title": "Friedländer-bacillus meningitis treated with streptomycin.", "content": "Friedländer-bacillus meningitis treated with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001785"}
{"pmid": "21001786", "title": "Otolaryngology.", "content": "Otolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001786"}
{"pmid": "21001787", "title": "Colloid carcinoma of gall bladder, with widespread metastases.", "content": "Colloid carcinoma of gall bladder, with widespread metastases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001787"}
{"pmid": "21001788", "title": "Fibrous dysplasia of rib.", "content": "Fibrous dysplasia of rib.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001788"}
{"pmid": "21001789", "title": "Acute hepatitis in civilian practice.", "content": "Acute hepatitis in civilian practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001789"}
{"pmid": "21001790", "title": "Experiences with late trench foot and frost-bite.", "content": "Experiences with late trench foot and frost-bite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001790"}
{"pmid": "21001791", "title": "Medical management of Graves' disease.", "content": "Medical management of Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001791"}
{"pmid": "21001792", "title": "Gastro-intestinal allergy.", "content": "Gastro-intestinal allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001792"}
{"pmid": "21001793", "title": "Venereal disease control in a rural area.", "content": "Venereal disease control in a rural area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001793"}
{"pmid": "21001794", "title": "Useful procedures in ambulant surgery.", "content": "Useful procedures in ambulant surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001794"}
{"pmid": "21001795", "title": "PROCUREMENT and use of biologicals in immunization and testing programs.", "content": "PROCUREMENT and use of biologicals in immunization and testing programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001795"}
{"pmid": "21001807", "title": "The management of acute intestinal obstruction.", "content": "The management of acute intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001807"}
{"pmid": "21001808", "title": "Anesthesia and analgesia in obstetrics.", "content": "Anesthesia and analgesia in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001808"}
{"pmid": "21001809", "title": "Continuous spinal anesthesia in obstetrics.", "content": "Continuous spinal anesthesia in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001809"}
{"pmid": "21001810", "title": "Caudal analgesia for obstetrics in private hospital.", "content": "Caudal analgesia for obstetrics in private hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001810"}
{"pmid": "21001811", "title": "The management of malaria.", "content": "The management of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001811"}
{"pmid": "21001812", "title": "The etiologic approach to chronic urticaria and angionerotic edema.", "content": "The etiologic approach to chronic urticaria and angionerotic edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001812"}
{"pmid": "21001813", "title": "Cyclopropane anesthesia; an evaluation of ten years of experience.", "content": "Cyclopropane anesthesia; an evaluation of ten years of experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001813"}
{"pmid": "21001814", "title": "The use of a pessary as an adjunct to early rising in the puerperium.", "content": "The use of a pessary as an adjunct to early rising in the puerperium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001814"}
{"pmid": "21001815", "title": "Volvulus of ileum with intertwining loops and knot formation.", "content": "Volvulus of ileum with intertwining loops and knot formation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001815"}
{"pmid": "21001816", "title": "American democracy and American medicine.", "content": "American democracy and American medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001816"}
{"pmid": "21001817", "title": "Advances in electro-coma therapy of psychoses.", "content": "Advances in electro-coma therapy of psychoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001817"}
{"pmid": "21001818", "title": "Coronary heart disease.", "content": "Coronary heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001818"}
{"pmid": "21001819", "title": "Diagnosis of non-traumatic intracranial lesions.", "content": "Diagnosis of non-traumatic intracranial lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001819"}
{"pmid": "21001820", "title": "War advances anesthesia.", "content": "War advances anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001820"}
{"pmid": "21001821", "title": "Pharmacology and therapeutic aspects of goiter; thiourea and thiouracil.", "content": "Pharmacology and therapeutic aspects of goiter; thiourea and thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001821"}
{"pmid": "21001822", "title": "Value and use of vital statistics in public health administration.", "content": "Value and use of vital statistics in public health administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001822"}
{"pmid": "21001823", "title": "The treatment of congestive heart failure.", "content": "The treatment of congestive heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001823"}
{"pmid": "21001824", "title": "Resection and bone transplantation in the treatment of bone sarcoma.", "content": "Resection and bone transplantation in the treatment of bone sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001824"}
{"pmid": "21001825", "title": "Pyruvic acid paste for removal of tissue slough.", "content": "Pyruvic acid paste for removal of tissue slough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001825"}
{"pmid": "21001826", "title": "Data concerning dietary disturbances following resection of the head of the pancreas for carcinoma.", "content": "Data concerning dietary disturbances following resection of the head of the pancreas for carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001826"}
{"pmid": "21001827", "title": "Penicillin therapy in pylephlebitis.", "content": "Penicillin therapy in pylephlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001827"}
{"pmid": "21001828", "title": "Principles involved in surgical therapy of encapsulated connective tissue malignancies.", "content": "Principles involved in surgical therapy of encapsulated connective tissue malignancies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001828"}
{"pmid": "21001829", "title": "Strangulation and perforation of a hernia caused by a foreign body.", "content": "Strangulation and perforation of a hernia caused by a foreign body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001829"}
{"pmid": "21001830", "title": "Congenital hypertrophic pyloric stenosis.", "content": "Congenital hypertrophic pyloric stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001830"}
{"pmid": "21001831", "title": "Fibrinogenopenia associated with multiple vitamin deficiencies and liver damage.", "content": "Fibrinogenopenia associated with multiple vitamin deficiencies and liver damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001831"}
{"pmid": "21001832", "title": "Clinical and hematological findings in multiple myeloma.", "content": "Clinical and hematological findings in multiple myeloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001832"}
{"pmid": "21001834", "title": "Folliculitis decalvans.", "content": "Folliculitis decalvans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001834"}
{"pmid": "21001833", "title": "Analysis of 1,400 consecutive gastroscopic examinations.", "content": "Analysis of 1,400 consecutive gastroscopic examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001833"}
{"pmid": "21001835", "title": "Eosinophilic granuloma.", "content": "Eosinophilic granuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001835"}
{"pmid": "21001836", "title": "Linear naevus treated by thorium X.", "content": "Linear naevus treated by thorium X.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001836"}
{"pmid": "21001837", "title": "Lichen sclerosus.", "content": "Lichen sclerosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001837"}
{"pmid": "21001838", "title": "Telangiectasia macularis eruptiva perstans.", "content": "Telangiectasia macularis eruptiva perstans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001838"}
{"pmid": "21001839", "title": "Bowen's disease associated with anaplastic carcinomatous tumour.", "content": "Bowen's disease associated with anaplastic carcinomatous tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001839"}
{"pmid": "21001840", "title": "Parapsoriasis.", "content": "Parapsoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001840"}
{"pmid": "21001841", "title": "Multiple achalasia, vertebral defects and retarded growth.", "content": "Multiple achalasia, vertebral defects and retarded growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001841"}
{"pmid": "21001842", "title": "Hypertensive retinopathy in a girl aged 10 years 11 months.", "content": "Hypertensive retinopathy in a girl aged 10 years 11 months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001842"}
{"pmid": "21001843", "title": "Exophthalmic goitre in a child aged 11 years.", "content": "Exophthalmic goitre in a child aged 11 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001843"}
{"pmid": "21001844", "title": "Primary hyperplasia of the parathyroids in a boy aged 8 years.", "content": "Primary hyperplasia of the parathyroids in a boy aged 8 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001844"}
{"pmid": "21001845", "title": "Tumour of the optic chiasm and nerve sheaths in a girl aged 2 years 9 months, showing some manifestations of neurofibromatosis.", "content": "Tumour of the optic chiasm and nerve sheaths in a girl aged 2 years 9 months, showing some manifestations of neurofibromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001845"}
{"pmid": "21001846", "title": "Familial haemolytic anaemia.", "content": "Familial haemolytic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001846"}
{"pmid": "21001847", "title": "Osteomyelitis and nephritis.", "content": "Osteomyelitis and nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001847"}
{"pmid": "21001848", "title": "Suppurative arthritis following bronchopneumonia.", "content": "Suppurative arthritis following bronchopneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001848"}
{"pmid": "21001850", "title": "Sarcoidosis.", "content": "Sarcoidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001850"}
{"pmid": "21001851", "title": "Lipodystrophy.", "content": "Lipodystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001851"}
{"pmid": "21001852", "title": "Case for diagnosis (congenital heart disease with atrial septal defect); mitral stenosis?", "content": "Case for diagnosis (congenital heart disease with atrial septal defect); mitral stenosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001852"}
{"pmid": "21001853", "title": "Pellagra.", "content": "Pellagra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001853"}
{"pmid": "21001854", "title": "Hypertension treated by arteriovenous anastomosis.", "content": "Hypertension treated by arteriovenous anastomosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001854"}
{"pmid": "21001855", "title": "Jejuno-gastric intussusception.", "content": "Jejuno-gastric intussusception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001855"}
{"pmid": "21001864", "title": "Avian leukaemia.", "content": "Avian leukaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001864"}
{"pmid": "21001865", "title": "Leukaemia in the dog.", "content": "Leukaemia in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001865"}
{"pmid": "21001869", "title": "[Anemia].", "content": "[Anemia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001869"}
{"pmid": "21001870", "title": "The disappearance of sulphaemoglobin from circulating blood in relation to red cell destruction.", "content": "The disappearance of sulphaemoglobin from circulating blood in relation to red cell destruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001870"}
{"pmid": "21001871", "title": "Background and highlights of the Rhode Island Hospital unit in the China-Burma-India Theatre of war.", "content": "Background and highlights of the Rhode Island Hospital unit in the China-Burma-India Theatre of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001871"}
{"pmid": "21001872", "title": "Overseas experiences with the medical service of the 48th Evacuation Hospital.", "content": "Overseas experiences with the medical service of the 48th Evacuation Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001872"}
{"pmid": "21001873", "title": "Overseas experiences with the surgical service of the 48th Evacuation Hospital.", "content": "Overseas experiences with the surgical service of the 48th Evacuation Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001873"}
{"pmid": "21001874", "title": "Experiences with sympathectomy.", "content": "Experiences with sympathectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001874"}
{"pmid": "21001875", "title": "Prolonged endotracheal oxygen; a case report.", "content": "Prolonged endotracheal oxygen; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001875"}
{"pmid": "21001876", "title": "The importance of the x-ray department.", "content": "The importance of the x-ray department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001876"}
{"pmid": "21001877", "title": "The doctor's answer to socialized medicine.", "content": "The doctor's answer to socialized medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001877"}
{"pmid": "21001878", "title": "On the use of electro-convulsive therapy as office procedure in certain mental disorders.", "content": "On the use of electro-convulsive therapy as office procedure in certain mental disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001878"}
{"pmid": "21001879", "title": "The use of penicillin in the treatment of syphilis.", "content": "The use of penicillin in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001879"}
{"pmid": "21001880", "title": "Scientific findings on death and coroner's inquest.", "content": "Scientific findings on death and coroner's inquest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001880"}
{"pmid": "21001881", "title": "Laboratory technics for the identification and evaluation of potentially antiepileptic drugs.", "content": "Laboratory technics for the identification and evaluation of potentially antiepileptic drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001881"}
{"pmid": "21001882", "title": "Relationships between acute rheumatic endocarditis and subacute bacterial endocarditis.", "content": "Relationships between acute rheumatic endocarditis and subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001882"}
{"pmid": "21001883", "title": "Pilonidal disease.", "content": "Pilonidal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001883"}
{"pmid": "21001884", "title": "Small bowel obstruction.", "content": "Small bowel obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001884"}
{"pmid": "21001885", "title": "Present trends in psychiatry.", "content": "Present trends in psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001885"}
{"pmid": "21001886", "title": "Advances in otology.", "content": "Advances in otology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001886"}
{"pmid": "21001914", "title": "The physician's responsibility to his community.", "content": "The physician's responsibility to his community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001914"}
{"pmid": "21001915", "title": "Choice of anesthetic and avoiding complications.", "content": "Choice of anesthetic and avoiding complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001915"}
{"pmid": "21001916", "title": "The treatment of Vincent's angina with penicillin.", "content": "The treatment of Vincent's angina with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001916"}
{"pmid": "21001917", "title": "Traumatic perforation of the ear drums.", "content": "Traumatic perforation of the ear drums.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001917"}
{"pmid": "21001918", "title": "Poliomyelitis.", "content": "Poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001918"}
{"pmid": "21001919", "title": "Critical review of fifty cases of urticaria.", "content": "Critical review of fifty cases of urticaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001919"}
{"pmid": "21001920", "title": "Blast concussion; observations re: handling.", "content": "Blast concussion; observations re: handling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001920"}
{"pmid": "21001921", "title": "IMMEDIATE postpartum repair of perineal lacerations.", "content": "IMMEDIATE postpartum repair of perineal lacerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001921"}
{"pmid": "21001922", "title": "Acute gastro-duodenal perforations.", "content": "Acute gastro-duodenal perforations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001922"}
{"pmid": "21001923", "title": "Tumors of the parotid.", "content": "Tumors of the parotid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001923"}
{"pmid": "21001924", "title": "Bronchiogenic carcinoma.", "content": "Bronchiogenic carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001924"}
{"pmid": "21001925", "title": "Bronchiectasis.", "content": "Bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001925"}
{"pmid": "21001926", "title": "Protein in surgery.", "content": "Protein in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001926"}
{"pmid": "21001927", "title": "Relative growth in a phylogenetic series and in an ontogenetic series of one of its members.", "content": "Relative growth in a phylogenetic series and in an ontogenetic series of one of its members.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001927"}
{"pmid": "21001928", "title": "Antibody production in the light of recent genetic theory.", "content": "Antibody production in the light of recent genetic theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001928"}
{"pmid": "21001929", "title": "Scientific method in the evolution of new drugs; the chemotherapy of tuberculosis.", "content": "Scientific method in the evolution of new drugs; the chemotherapy of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001929"}
{"pmid": "21001930", "title": "The surface area of fine powders.", "content": "The surface area of fine powders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001930"}
{"pmid": "21001931", "title": "Records of Anopheles (Diptera, Culicidae) from high altitudes in New Guinea.", "content": "Records of Anopheles (Diptera, Culicidae) from high altitudes in New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001931"}
{"pmid": "21001932", "title": "Recent advances in plant protectant fungicides.", "content": "Recent advances in plant protectant fungicides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001932"}
{"pmid": "21001933", "title": "The red blood cell and the mode of action of some haemolysins and haemagglutinins.", "content": "The red blood cell and the mode of action of some haemolysins and haemagglutinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001933"}
{"pmid": "21001934", "title": "Restoring international cooperation in science.", "content": "Restoring international cooperation in science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001934"}
{"pmid": "21001935", "title": "Hydrogenase.", "content": "Hydrogenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001935"}
{"pmid": "21001936", "title": "Application of interferometry to biological surfaces.", "content": "Application of interferometry to biological surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001936"}
{"pmid": "21001937", "title": "Effect of molybdenum on nitrogen fixation by Clostridium butyricum.", "content": "Effect of molybdenum on nitrogen fixation by Clostridium butyricum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001937"}
{"pmid": "21001938", "title": "BALANCE of scientific man-power in Britain.", "content": "BALANCE of scientific man-power in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001938"}
{"pmid": "21001939", "title": "Analysis of the electrical response of the human cortex to photic stimulation.", "content": "Analysis of the electrical response of the human cortex to photic stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001939"}
{"pmid": "21001940", "title": "An electronic method of tracing the movements of beetles in the field.", "content": "An electronic method of tracing the movements of beetles in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001940"}
{"pmid": "21001941", "title": "Man's reaction to mosquito bites.", "content": "Man's reaction to mosquito bites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001941"}
{"pmid": "21001942", "title": "Penicillin as a plant hormone.", "content": "Penicillin as a plant hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001942"}
{"pmid": "21001943", "title": "Adrenal cortical hormone and pigmentation.", "content": "Adrenal cortical hormone and pigmentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001943"}
{"pmid": "21001944", "title": "Sulphonamides and the thyroid gland.", "content": "Sulphonamides and the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001944"}
{"pmid": "21001945", "title": "Gene recombination in Escherichia coli.", "content": "Gene recombination in Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001945"}
{"pmid": "21001946", "title": "Dental condition of five-year-old elementary school children.", "content": "Dental condition of five-year-old elementary school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001946"}
{"pmid": "21001947", "title": "Limits of effective human power.", "content": "Limits of effective human power.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001947"}
{"pmid": "21001949", "title": "Phase microscopy, its development and utility.", "content": "Phase microscopy, its development and utility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001949"}
{"pmid": "21001948", "title": "The deterioration of materiel in the tropics.", "content": "The deterioration of materiel in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001948"}
{"pmid": "21001950", "title": "Relative cooling requirements for American homes.", "content": "Relative cooling requirements for American homes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001950"}
{"pmid": "21001952", "title": "Climate as a natural resource.", "content": "Climate as a natural resource.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001952"}
{"pmid": "21001951", "title": "Ira Remsen and Roger Adams, a chemical centennial.", "content": "Ira Remsen and Roger Adams, a chemical centennial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001951"}
{"pmid": "21001953", "title": "Do you know a dyslexiac?", "content": "Do you know a dyslexiac?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001953"}
{"pmid": "21001954", "title": "Synthetic penicillin.", "content": "Synthetic penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001954"}
{"pmid": "21001955", "title": "The influence of liver L. casei factor on spontaneous breast cancer in mice.", "content": "The influence of liver L. casei factor on spontaneous breast cancer in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001955"}
{"pmid": "21001956", "title": "Stability of carotene in dehydrated carrots impregnated with antioxidants.", "content": "Stability of carotene in dehydrated carrots impregnated with antioxidants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001956"}
{"pmid": "21001958", "title": "EXHIBIT of books, prints, and manuscripts on the development of anesthesia, to commemorate with the Army Medical Library the 100th anniversary of the first public demonstration of ether anesthesia, opened in the Library of Congress on 16 October 1946.", "content": "EXHIBIT of books, prints, and manuscripts on the development of anesthesia, to commemorate with the Army Medical Library the 100th anniversary of the first public demonstration of ether anesthesia, opened in the Library of Congress on 16 October 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001958"}
{"pmid": "21001959", "title": "Synthetic media for penicillin production.", "content": "Synthetic media for penicillin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001959"}
{"pmid": "21001961", "title": "Wholeblood cholinesterase determinations in some hematologic dyscrasias; low cholinesterase values in the leucoses.", "content": "Wholeblood cholinesterase determinations in some hematologic dyscrasias; low cholinesterase values in the leucoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001961"}
{"pmid": "21001962", "title": "The entomology of stored products.", "content": "The entomology of stored products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001962"}
{"pmid": "21001963", "title": "Recent progress in industrial mycology.", "content": "Recent progress in industrial mycology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001963"}
{"pmid": "21001964", "title": "Colour.", "content": "Colour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001964"}
{"pmid": "21001965", "title": "The geochemistry of uranium.", "content": "The geochemistry of uranium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001965"}
{"pmid": "21001966", "title": "Gaps in the scientific evidence for the prosecution.", "content": "Gaps in the scientific evidence for the prosecution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001966"}
{"pmid": "21001967", "title": "Starch and glycogen.", "content": "Starch and glycogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001967"}
{"pmid": "21001968", "title": "Plant physiology.", "content": "Plant physiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001968"}
{"pmid": "21001969", "title": "The encephalopathy (kernicterus) of erythroblastosis fetalis, its serologic diagnosis and pathogenesis.", "content": "The encephalopathy (kernicterus) of erythroblastosis fetalis, its serologic diagnosis and pathogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001969"}
{"pmid": "21001970", "title": "The contribution of projective techniques to the understanding and treatment of children psychometrically diagnosed as feeble-minded; with sample case studies.", "content": "The contribution of projective techniques to the understanding and treatment of children psychometrically diagnosed as feeble-minded; with sample case studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001970"}
{"pmid": "21001971", "title": "Retest results on the Stanford L with mental defectives.", "content": "Retest results on the Stanford L with mental defectives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001971"}
{"pmid": "21001972", "title": "Study of three boys whose birth and early years were in a psychopathic hospital.", "content": "Study of three boys whose birth and early years were in a psychopathic hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001972"}
{"pmid": "21001973", "title": "The readjustment of the mentally deficient soldier in the community.", "content": "The readjustment of the mentally deficient soldier in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001973"}
{"pmid": "21001974", "title": "A program for dealing with mental deficiency in children up to six years of age.", "content": "A program for dealing with mental deficiency in children up to six years of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001974"}
{"pmid": "21001975", "title": "A study of psychopathic delinquency.", "content": "A study of psychopathic delinquency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001975"}
{"pmid": "21001976", "title": "Levels of intelligence of prison inmates.", "content": "Levels of intelligence of prison inmates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001976"}
{"pmid": "21001977", "title": "Illinois plans for its educable mentally handicapped children.", "content": "Illinois plans for its educable mentally handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001977"}
{"pmid": "21001979", "title": "What the state school should mean to the community.", "content": "What the state school should mean to the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001979"}
{"pmid": "21001978", "title": "The organization of a rehabilitation program for the mentally deficient.", "content": "The organization of a rehabilitation program for the mentally deficient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001978"}
{"pmid": "21001980", "title": "A complete social program for the mentally retarded.", "content": "A complete social program for the mentally retarded.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001980"}
{"pmid": "21001981", "title": "Psychiatry in industry.", "content": "Psychiatry in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001981"}
{"pmid": "21001982", "title": "Current trends in industrial psychiatry.", "content": "Current trends in industrial psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001982"}
{"pmid": "21001983", "title": "Epilepsy; treatment with new drug; 3-methyl 5,5-phenyl-ethyl-hydantoin (phenantoin).", "content": "Epilepsy; treatment with new drug; 3-methyl 5,5-phenyl-ethyl-hydantoin (phenantoin).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001983"}
{"pmid": "21001984", "title": "Two new drugs in epilepsy therapy.", "content": "Two new drugs in epilepsy therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001984"}
{"pmid": "21001985", "title": "Further observations on the use of tridione in the control of psychomotor attacks.", "content": "Further observations on the use of tridione in the control of psychomotor attacks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001985"}
{"pmid": "21001986", "title": "Incidence of neuropsychiatric disease in the demobilized veteran; a study of 10,000 Army separates.", "content": "Incidence of neuropsychiatric disease in the demobilized veteran; a study of 10,000 Army separates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001986"}
{"pmid": "21001987", "title": "Rehabilitation of military offenders at the Ninth Service Command Rehabilitation Center.", "content": "Rehabilitation of military offenders at the Ninth Service Command Rehabilitation Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001987"}
{"pmid": "21001988", "title": "A study of the modification of mental illness by intercurrent physical disorders in one hundred patients.", "content": "A study of the modification of mental illness by intercurrent physical disorders in one hundred patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001988"}
{"pmid": "21001989", "title": "Nail biting; incidence, allied personality traits and military significance.", "content": "Nail biting; incidence, allied personality traits and military significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001989"}
{"pmid": "21001990", "title": "A psychosomatic approach to the problem of stuttering in psychotics.", "content": "A psychosomatic approach to the problem of stuttering in psychotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001990"}
{"pmid": "21001991", "title": "Comparative incidence of neuropsychiatric casualties in World War I and World War II.", "content": "Comparative incidence of neuropsychiatric casualties in World War I and World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001991"}
{"pmid": "21001992", "title": "Psychiatry in Hanford.", "content": "Psychiatry in Hanford.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001992"}
{"pmid": "21001993", "title": "Men with brain damage.", "content": "Men with brain damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001993"}
{"pmid": "21001994", "title": "Japanese military psychiatry in Korea.", "content": "Japanese military psychiatry in Korea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001994"}
{"pmid": "21001995", "title": "Prefrontal lobotomy; a preliminary appraisal of the behavioral results.", "content": "Prefrontal lobotomy; a preliminary appraisal of the behavioral results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001995"}
{"pmid": "21001996", "title": "Transitory schizophrenias produced by bromide intoxication.", "content": "Transitory schizophrenias produced by bromide intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001996"}
{"pmid": "21001997", "title": "Orbital cortex syndrome following leucotomy.", "content": "Orbital cortex syndrome following leucotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001997"}
{"pmid": "21001998", "title": "Irrelevant and metaphorical language in early infantile autism.", "content": "Irrelevant and metaphorical language in early infantile autism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001998"}
{"pmid": "21001999", "title": "Glucose tolerance in chronic alcoholism.", "content": "Glucose tolerance in chronic alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21001999"}
{"pmid": "21002000", "title": "Reconditioning the neurosurgical patient.", "content": "Reconditioning the neurosurgical patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002000"}
{"pmid": "21002001", "title": "Paranoia and paranoiac reaction types (a summary of eight case histories).", "content": "Paranoia and paranoiac reaction types (a summary of eight case histories).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002001"}
{"pmid": "21002002", "title": "[Softening, right midbrain, and bilaterally in the superior portion of the cerebellar hemispheres on the basis of vasothrombosis].", "content": "[Softening, right midbrain, and bilaterally in the superior portion of the cerebellar hemispheres on the basis of vasothrombosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002002"}
{"pmid": "21002003", "title": "Comment on a near fatality from curare.", "content": "Comment on a near fatality from curare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002003"}
{"pmid": "21002004", "title": "Standard treatment of epilepsy.", "content": "Standard treatment of epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002004"}
{"pmid": "21002005", "title": "Remarks on the predictability factor in psychosomatic relations.", "content": "Remarks on the predictability factor in psychosomatic relations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002005"}
{"pmid": "21002006", "title": "Some psychosomatic aspects of childhood.", "content": "Some psychosomatic aspects of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002006"}
{"pmid": "21002007", "title": "A contribution to the study of the genesis of psychosomatic disorders.", "content": "A contribution to the study of the genesis of psychosomatic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002007"}
{"pmid": "21002008", "title": "The psychic effect of pertussis; report of a case.", "content": "The psychic effect of pertussis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002008"}
{"pmid": "21002009", "title": "Bronchial asthma in children.", "content": "Bronchial asthma in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002009"}
{"pmid": "21002010", "title": "The relations to the mother as seen in cases of allergy.", "content": "The relations to the mother as seen in cases of allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002010"}
{"pmid": "21002011", "title": "Psychosomatic aspects of dermatology with special consideration of allergic phenomena.", "content": "Psychosomatic aspects of dermatology with special consideration of allergic phenomena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002011"}
{"pmid": "21002012", "title": "Tic convulsif as a psychosomatic problem.", "content": "Tic convulsif as a psychosomatic problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002012"}
{"pmid": "21002013", "title": "Allergic reaction in a case treated with curare-electric shock, followed by recrudescence of the psychosis.", "content": "Allergic reaction in a case treated with curare-electric shock, followed by recrudescence of the psychosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002013"}
{"pmid": "21002014", "title": "From VJ; mental disorder following service discharge.", "content": "From VJ; mental disorder following service discharge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002014"}
{"pmid": "21002015", "title": "A statistical investigation of the incidence of mental disorder in Norway.", "content": "A statistical investigation of the incidence of mental disorder in Norway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002015"}
{"pmid": "21002016", "title": "Obesity and neurosis; a case report.", "content": "Obesity and neurosis; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002016"}
{"pmid": "21002017", "title": "Further studies in the use of adrenalin in the treatment of persistent anxiety states.", "content": "Further studies in the use of adrenalin in the treatment of persistent anxiety states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002017"}
{"pmid": "21002018", "title": "Psychiatric reactions to wartime stress as seen in members of the armed services, referred to a private mental hospital.", "content": "Psychiatric reactions to wartime stress as seen in members of the armed services, referred to a private mental hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002018"}
{"pmid": "21002019", "title": "Pathological lesions disclosed at autopsy in cases of amebic dysentery.", "content": "Pathological lesions disclosed at autopsy in cases of amebic dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002019"}
{"pmid": "21002020", "title": "The management of the emotionally maladjusted soldier at a staging camp.", "content": "The management of the emotionally maladjusted soldier at a staging camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002020"}
{"pmid": "21002021", "title": "Group psychotherapy as developed in a military setting; its application to civilian therapy.", "content": "Group psychotherapy as developed in a military setting; its application to civilian therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002021"}
{"pmid": "21002022", "title": "Homosexuality; with special reference to military prisoners.", "content": "Homosexuality; with special reference to military prisoners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002022"}
{"pmid": "21002023", "title": "The measurement and correction of hyperphorias in refractive cases.", "content": "The measurement and correction of hyperphorias in refractive cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002023"}
{"pmid": "21002024", "title": "Some principles of nomenclature.", "content": "Some principles of nomenclature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002024"}
{"pmid": "21002025", "title": "A report on two unusual contact lens cases.", "content": "A report on two unusual contact lens cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002025"}
{"pmid": "21002026", "title": "The nurse in an industrial vision program.", "content": "The nurse in an industrial vision program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002026"}
{"pmid": "21002027", "title": "Accommodative convergence in squinters.", "content": "Accommodative convergence in squinters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002027"}
{"pmid": "21002028", "title": "The after effect of lateral duction testing on subsequent phoria measurements.", "content": "The after effect of lateral duction testing on subsequent phoria measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002028"}
{"pmid": "21002029", "title": "The present situation and the prospects for the immediate future of the Los Angeles School of Optometry with some personal comment on optometric education in its larger aspects.", "content": "The present situation and the prospects for the immediate future of the Los Angeles School of Optometry with some personal comment on optometric education in its larger aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002029"}
{"pmid": "21002030", "title": "The Cantonnet system from the viewpoint of general psychology.", "content": "The Cantonnet system from the viewpoint of general psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002030"}
{"pmid": "21002031", "title": "Congenital encephalo-ophthalmic dysplasia.", "content": "Congenital encephalo-ophthalmic dysplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002031"}
{"pmid": "21002032", "title": "Etiology and treatment of blepharitis; a study in military personnel.", "content": "Etiology and treatment of blepharitis; a study in military personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002032"}
{"pmid": "21002033", "title": "Retrobulbar neuritis and complete heart block caused by digitalis poisoning; report of case.", "content": "Retrobulbar neuritis and complete heart block caused by digitalis poisoning; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002033"}
{"pmid": "21002034", "title": "Exposure and fixation of the eye in the early days of cataract extraction.", "content": "Exposure and fixation of the eye in the early days of cataract extraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002034"}
{"pmid": "21002035", "title": "Clinical-pathologic correlations in cases of enucleation of the globe.", "content": "Clinical-pathologic correlations in cases of enucleation of the globe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002035"}
{"pmid": "21002036", "title": "Removal of a foreign body from the orbit with aid of the Berman localizer.", "content": "Removal of a foreign body from the orbit with aid of the Berman localizer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002036"}
{"pmid": "21002037", "title": "Opthalmoscopic changes associated with essential hypertension as a guide to sympathectomy [discussion of a paper by M. Cohen not yet published].", "content": "Opthalmoscopic changes associated with essential hypertension as a guide to sympathectomy [discussion of a paper by M. Cohen not yet published].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002037"}
{"pmid": "21002038", "title": "The fluorescence of phosphors in rare gases.", "content": "The fluorescence of phosphors in rare gases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002038"}
{"pmid": "21002039", "title": "A method of quantitative spectrochemical analysis based on line widths.", "content": "A method of quantitative spectrochemical analysis based on line widths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002039"}
{"pmid": "21002040", "title": "A theory of the Stiles and Crawford effect.", "content": "A theory of the Stiles and Crawford effect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002040"}
{"pmid": "21002041", "title": "A reflectance measuring attachment for the Beckman spectrophotometer.", "content": "A reflectance measuring attachment for the Beckman spectrophotometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002041"}
{"pmid": "21002042", "title": "A fast superconducting bolometer.", "content": "A fast superconducting bolometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002042"}
{"pmid": "21002043", "title": "Radiation in a diffusing medium.", "content": "Radiation in a diffusing medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002043"}
{"pmid": "21002044", "title": "[Preparation of ophthalmological cadres].", "content": "[Preparation of ophthalmological cadres].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002044"}
{"pmid": "21002045", "title": "[Work of the rear ophthalmological evacuation hospitals under new conditions].", "content": "[Work of the rear ophthalmological evacuation hospitals under new conditions].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002045"}
{"pmid": "21002046", "title": "[Optic operations in sub-atrophy of the eye].", "content": "[Optic operations in sub-atrophy of the eye].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002046"}
{"pmid": "21002047", "title": "[Plastic restoration of the eyelids using the round pedicle].", "content": "[Plastic restoration of the eyelids using the round pedicle].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002047"}
{"pmid": "21002048", "title": "[Wound processes in the eye].", "content": "[Wound processes in the eye].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002048"}
{"pmid": "21002049", "title": "[Use of conjunctiva in plastic repair of the cornea according to the method of Kuhnt].", "content": "[Use of conjunctiva in plastic repair of the cornea according to the method of Kuhnt].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002049"}
{"pmid": "21002050", "title": "[Comparative evaluation of treatment of fresh wounds of the eyeball by Kuhnt's method and by the use of sutures].", "content": "[Comparative evaluation of treatment of fresh wounds of the eyeball by Kuhnt's method and by the use of sutures].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002050"}
{"pmid": "21002051", "title": "[Conjunctival plastic by Kuhnt's method in war injuries of the cornea].", "content": "[Conjunctival plastic by Kuhnt's method in war injuries of the cornea].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002051"}
{"pmid": "21002052", "title": "[Focal infection and the eye].", "content": "[Focal infection and the eye].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002052"}
{"pmid": "21002053", "title": "[Choice of substitutes in protein therapy in war conditions].", "content": "[Choice of substitutes in protein therapy in war conditions].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002053"}
{"pmid": "21002054", "title": "[Experience in treatment of war wounds of the eyes in the division of restorative ophthalmological surgery].", "content": "[Experience in treatment of war wounds of the eyes in the division of restorative ophthalmological surgery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002054"}
{"pmid": "21002056", "title": "Osteomyelitis of the maxilla secondary to suppurative maxillary sinusitis.", "content": "Osteomyelitis of the maxilla secondary to suppurative maxillary sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002056"}
{"pmid": "21002055", "title": "The development of the auditory ossicles and associated structures in man.", "content": "The development of the auditory ossicles and associated structures in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002055"}
{"pmid": "21002057", "title": "The danger of unrecognized anoxia in laryngology.", "content": "The danger of unrecognized anoxia in laryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002057"}
{"pmid": "21002058", "title": "Intranasal medication; an investigation into the relative merits of certain methods of introducing fluids into the nose.", "content": "Intranasal medication; an investigation into the relative merits of certain methods of introducing fluids into the nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002058"}
{"pmid": "21002059", "title": "Aphonia.", "content": "Aphonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002059"}
{"pmid": "21002060", "title": "Intralaryngeal operation for cancer of the vocal cord.", "content": "Intralaryngeal operation for cancer of the vocal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002060"}
{"pmid": "21002061", "title": "Some causes of hoarseness in children.", "content": "Some causes of hoarseness in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002061"}
{"pmid": "21002062", "title": "Endaural approach to the mastoid for complete mastoidectomy, with report of 43 operations.", "content": "Endaural approach to the mastoid for complete mastoidectomy, with report of 43 operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002062"}
{"pmid": "21002063", "title": "Associated paralyses of the larynx.", "content": "Associated paralyses of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002063"}
{"pmid": "21002064", "title": "Aids in rhinoplastic procedures.", "content": "Aids in rhinoplastic procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002064"}
{"pmid": "21002065", "title": "Cleft palate.", "content": "Cleft palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002065"}
{"pmid": "21002066", "title": "Rhinosporidiosis.", "content": "Rhinosporidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002066"}
{"pmid": "21002067", "title": "Tonsillectomy and poliomyelitis.", "content": "Tonsillectomy and poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002067"}
{"pmid": "21002068", "title": "Tonsillectomy and poliomyelitis.", "content": "Tonsillectomy and poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002068"}
{"pmid": "21002069", "title": "Catheterizing bronchoscope and angulated bronchial forceps.", "content": "Catheterizing bronchoscope and angulated bronchial forceps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002069"}
{"pmid": "21002070", "title": "Magnets for the extraction of foreign bodies from the air and food passages.", "content": "Magnets for the extraction of foreign bodies from the air and food passages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002070"}
{"pmid": "21002071", "title": "Aplasia of the lung.", "content": "Aplasia of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002071"}
{"pmid": "21002072", "title": "Agenesis of the right lung; with death following aspiration of foreign bodies into the left lung.", "content": "Agenesis of the right lung; with death following aspiration of foreign bodies into the left lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002072"}
{"pmid": "21002073", "title": "Penicillin therapy in the trachea and bronchi.", "content": "Penicillin therapy in the trachea and bronchi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002073"}
{"pmid": "21002075", "title": "Points of mutual interest in bronchology and anesthesiology.", "content": "Points of mutual interest in bronchology and anesthesiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002075"}
{"pmid": "21002074", "title": "Boeck's sarcoid; a brief review and report of a case in which diagnosis was made by bronchoscopic examination and biopsy.", "content": "Boeck's sarcoid; a brief review and report of a case in which diagnosis was made by bronchoscopic examination and biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002074"}
{"pmid": "21002076", "title": "Diagnosis of bronchogenic carcinoma by examination of bronchial secretions.", "content": "Diagnosis of bronchogenic carcinoma by examination of bronchial secretions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002076"}
{"pmid": "21002077", "title": "Injuries to the trachea and the esophagus incurred in combat.", "content": "Injuries to the trachea and the esophagus incurred in combat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002077"}
{"pmid": "21002078", "title": "Perforation of the esophagus not caused by instrumentation; review of eight cases.", "content": "Perforation of the esophagus not caused by instrumentation; review of eight cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002078"}
{"pmid": "21002079", "title": "Endolaryngeal surgery combined with radiation in late laryngeal cancer.", "content": "Endolaryngeal surgery combined with radiation in late laryngeal cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002079"}
{"pmid": "21002080", "title": "Congenital cyst of the mediastinum producing compression of the lower trachea and esophagus.", "content": "Congenital cyst of the mediastinum producing compression of the lower trachea and esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002080"}
{"pmid": "21002081", "title": "The normal and the pathologic structure of the fissular region of the temporal bone.", "content": "The normal and the pathologic structure of the fissular region of the temporal bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002081"}
{"pmid": "21002083", "title": "Osteomyelitis of the lower jaw and the rational use of chemotherapeutic agents.", "content": "Osteomyelitis of the lower jaw and the rational use of chemotherapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002083"}
{"pmid": "21002082", "title": "Factors influencing osteogenesis following the fenestration operation; observations on the monkey.", "content": "Factors influencing osteogenesis following the fenestration operation; observations on the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002082"}
{"pmid": "21002084", "title": "Ménière's syndrome; the basic fault?", "content": "Ménière's syndrome; the basic fault?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002084"}
{"pmid": "21002085", "title": "War injuries to the mastoid and the facial nerve.", "content": "War injuries to the mastoid and the facial nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002085"}
{"pmid": "21002086", "title": "Abnormal course of the facial nerve in the Fallopian canal.", "content": "Abnormal course of the facial nerve in the Fallopian canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002086"}
{"pmid": "21002087", "title": "Penicillin in the oral therapy of Vincent's angina and acute follicular tonsillitis.", "content": "Penicillin in the oral therapy of Vincent's angina and acute follicular tonsillitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002087"}
{"pmid": "21002088", "title": "Rhinitis and eustachian salpingitis.", "content": "Rhinitis and eustachian salpingitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002088"}
{"pmid": "21002089", "title": "Neuralgic syndromes of the head: anatomy and physiology of sensory nerves to the head.", "content": "Neuralgic syndromes of the head: anatomy and physiology of sensory nerves to the head.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002089"}
{"pmid": "21002090", "title": "Fractures of the malar-zygomatic compound; treatment by improved methods and myoplasty.", "content": "Fractures of the malar-zygomatic compound; treatment by improved methods and myoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002090"}
{"pmid": "21002091", "title": "Free voice and pure tone audiometer for routine testing of auditory acuity; studies on comparative efficiency.", "content": "Free voice and pure tone audiometer for routine testing of auditory acuity; studies on comparative efficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002091"}
{"pmid": "21002092", "title": "Local use of penicillin and of sulfathiazole for acute and chronic sinusitis.", "content": "Local use of penicillin and of sulfathiazole for acute and chronic sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002092"}
{"pmid": "21002093", "title": "Effect of sulfonamide drugs on mucous membranes; an experimental study of the action of the newer sulfonamide drugs on the mucous membranes of rabbits.", "content": "Effect of sulfonamide drugs on mucous membranes; an experimental study of the action of the newer sulfonamide drugs on the mucous membranes of rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002093"}
{"pmid": "21002094", "title": "Bifid nose associated with midline cleft of the upper lip.", "content": "Bifid nose associated with midline cleft of the upper lip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002094"}
{"pmid": "21002095", "title": "Functional examination of hearing.", "content": "Functional examination of hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002095"}
{"pmid": "21002096", "title": "[Experience in treatment of certain ear nose and throat diseases with reversible emulsion of sulfonamide].", "content": "[Experience in treatment of certain ear nose and throat diseases with reversible emulsion of sulfonamide].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002096"}
{"pmid": "21002097", "title": "[Clinics and therapy of barotraumatic otitis].", "content": "[Clinics and therapy of barotraumatic otitis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002097"}
{"pmid": "21002098", "title": "[Phenamine and its effect on function of the hearing organ].", "content": "[Phenamine and its effect on function of the hearing organ].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002098"}
{"pmid": "21002099", "title": "[Treatment of external otitis with staphylococcic anatoxin].", "content": "[Treatment of external otitis with staphylococcic anatoxin].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002099"}
{"pmid": "21002100", "title": "[Experience with use of Bogomolets's ACS in treatment of slow-healing wounds following trepanations of the mastoid process].", "content": "[Experience with use of Bogomolets's ACS in treatment of slow-healing wounds following trepanations of the mastoid process].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002100"}
{"pmid": "21002101", "title": "[Experience with the use of Bogomolets's ACS in acute inflammatory processes in the pharynx and larynx].", "content": "[Experience with the use of Bogomolets's ACS in acute inflammatory processes in the pharynx and larynx].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002101"}
{"pmid": "21002102", "title": "[Experience with the use of Bogomolets's ACS in ozena].", "content": "[Experience with the use of Bogomolets's ACS in ozena].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002102"}
{"pmid": "21002103", "title": "[Use of bacteriophage in treatment of wounds in oto-rhino-laryngology].", "content": "[Use of bacteriophage in treatment of wounds in oto-rhino-laryngology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002103"}
{"pmid": "21002104", "title": "[Treatment of trepanations of the temporal bone with white streptocide].", "content": "[Treatment of trepanations of the temporal bone with white streptocide].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002104"}
{"pmid": "21002105", "title": "[Use of Vishnievski's ointment in treatment of wounds of the postaural region].", "content": "[Use of Vishnievski's ointment in treatment of wounds of the postaural region].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002105"}
{"pmid": "21002106", "title": "[A pelote for fixation of the palate].", "content": "[A pelote for fixation of the palate].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002106"}
{"pmid": "21002107", "title": "[Methods of removal of intranasal synechiae].", "content": "[Methods of removal of intranasal synechiae].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002107"}
{"pmid": "21002108", "title": "[Intubation under visual control].", "content": "[Intubation under visual control].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002108"}
{"pmid": "21002109", "title": "[A method of intubation under visual control].", "content": "[A method of intubation under visual control].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002109"}
{"pmid": "21002111", "title": "[Diagnosis and treatment of the so-called latent otitis and antritis of infants].", "content": "[Diagnosis and treatment of the so-called latent otitis and antritis of infants].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002111"}
{"pmid": "21002110", "title": "[A new incision of the soft tissues in antrotomy in infants].", "content": "[A new incision of the soft tissues in antrotomy in infants].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002110"}
{"pmid": "21002112", "title": "[Characteristics of cholesteatoma of the ear in children].", "content": "[Characteristics of cholesteatoma of the ear in children].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002112"}
{"pmid": "21002113", "title": "[Measles otitis in Moscow during the second half of 1941].", "content": "[Measles otitis in Moscow during the second half of 1941].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002113"}
{"pmid": "21002114", "title": "[Military oto-rhino-laryngology].", "content": "[Military oto-rhino-laryngology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002114"}
{"pmid": "21002115", "title": "[Treatment of gunshot wounds of the LOR-organs and of the neck; experience in work of a LOR-department of a military hospital].", "content": "[Treatment of gunshot wounds of the LOR-organs and of the neck; experience in work of a LOR-department of a military hospital].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002115"}
{"pmid": "21002116", "title": "[Oto-laryngological service at the front].", "content": "[Oto-laryngological service at the front].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002116"}
{"pmid": "21002117", "title": "[Gunshot injuries of the sublingual nerve].", "content": "[Gunshot injuries of the sublingual nerve].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002117"}
{"pmid": "21002118", "title": "[Experience with the use of colloid hen's glair-ovoprotein in the LOR-clinic].", "content": "[Experience with the use of colloid hen's glair-ovoprotein in the LOR-clinic].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002118"}
{"pmid": "21002119", "title": "[History of St. Petersburg LOR-schools].", "content": "[History of St. Petersburg LOR-schools].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002119"}
{"pmid": "21002120", "title": "The present status of the Rh factor.", "content": "The present status of the Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002120"}
{"pmid": "21002121", "title": "Contrast coloring of media by dyes in growing tubercle bacilli; effect of dyes on growth of tubercle bacilli.", "content": "Contrast coloring of media by dyes in growing tubercle bacilli; effect of dyes on growth of tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002121"}
{"pmid": "21002122", "title": "The reactions of tissue to cold; the pathology of frostbite, high altitude frostbite, trench foot and immersion foot.", "content": "The reactions of tissue to cold; the pathology of frostbite, high altitude frostbite, trench foot and immersion foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002122"}
{"pmid": "21002123", "title": "Cirrhosis of the liver and diabetes as related to hemochromatosis.", "content": "Cirrhosis of the liver and diabetes as related to hemochromatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002123"}
{"pmid": "21002124", "title": "Glycogen-storage disease of the heart.", "content": "Glycogen-storage disease of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002124"}
{"pmid": "21002125", "title": "The effect of the administration of p-dimethyl-p-aminoazobenzene on the ovarian functions of rats.", "content": "The effect of the administration of p-dimethyl-p-aminoazobenzene on the ovarian functions of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002125"}
{"pmid": "21002126", "title": "Studies on the detoxication of the labile rickettsia toxin.", "content": "Studies on the detoxication of the labile rickettsia toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002126"}
{"pmid": "21002127", "title": "Spontaneous crystallization of a protein from pathological human serum.", "content": "Spontaneous crystallization of a protein from pathological human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002127"}
{"pmid": "21002128", "title": "Modification of human red cells by virus action; the receptor gradient for virus action in human red cells.", "content": "Modification of human red cells by virus action; the receptor gradient for virus action in human red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002128"}
{"pmid": "21002129", "title": "Modification of human red cells by virus action; agglutination of modified human red cells by sera from cases of infectious mononucleosis.", "content": "Modification of human red cells by virus action; agglutination of modified human red cells by sera from cases of infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002129"}
{"pmid": "21002130", "title": "Modification of human red cells by virus action; a sensitive test for mumps antibody in human serum by the agglutination of human red cells coated with a virus antigen.", "content": "Modification of human red cells by virus action; a sensitive test for mumps antibody in human serum by the agglutination of human red cells coated with a virus antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002130"}
{"pmid": "21002131", "title": "The thyrotrophic hormone and thiourea in reference to the problem of antihormones.", "content": "The thyrotrophic hormone and thiourea in reference to the problem of antihormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002131"}
{"pmid": "21002132", "title": "An electron microscope study of the contents of hair cells from leaves diseased with tobacco mosaic virus.", "content": "An electron microscope study of the contents of hair cells from leaves diseased with tobacco mosaic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002132"}
{"pmid": "21002133", "title": "Cardiac enlargement in infancy; report of case.", "content": "Cardiac enlargement in infancy; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002133"}
{"pmid": "21002134", "title": "The toxic diseases of the newborn; preliminary report.", "content": "The toxic diseases of the newborn; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002134"}
{"pmid": "21002135", "title": "Amaurotic family idiocy (Tay-Sach's disease); the infantile type.", "content": "Amaurotic family idiocy (Tay-Sach's disease); the infantile type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002135"}
{"pmid": "21002141", "title": "Oral manifestations of congenital heart disease.", "content": "Oral manifestations of congenital heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002141"}
{"pmid": "21002142", "title": "The use of a sulfadiazine-sulfathiazole mixture in the treatment of children.", "content": "The use of a sulfadiazine-sulfathiazole mixture in the treatment of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002142"}
{"pmid": "21002143", "title": "To what extent does fluorine ingestion lessen tooth decay?", "content": "To what extent does fluorine ingestion lessen tooth decay?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002143"}
{"pmid": "21002144", "title": "Wilms' tumor.", "content": "Wilms' tumor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002144"}
{"pmid": "21002145", "title": "A developmental graph for the first year of life.", "content": "A developmental graph for the first year of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002145"}
{"pmid": "21002136", "title": "Physical growth from birth to two years; head circumference; a review and synthesis of North American research on groups of infants.", "content": "Physical growth from birth to two years; head circumference; a review and synthesis of North American research on groups of infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002136"}
{"pmid": "21002138", "title": "Biological and medical studies at the Samuel S. Fels Research Institute.", "content": "Biological and medical studies at the Samuel S. Fels Research Institute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002138"}
{"pmid": "21002146", "title": "Virus pneumonia.", "content": "Virus pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002146"}
{"pmid": "21002137", "title": "Father-fantasies and father-typing in father-separated children.", "content": "Father-fantasies and father-typing in father-separated children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002137"}
{"pmid": "21002147", "title": "Growth of children with diabetes mellitus in relationship to level of control of the disease.", "content": "Growth of children with diabetes mellitus in relationship to level of control of the disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002147"}
{"pmid": "21002148", "title": "The hypoxia tolerance test of the heart in children.", "content": "The hypoxia tolerance test of the heart in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002148"}
{"pmid": "21002149", "title": "Stramonium poisoning; a diagnostic problem with psychiatric implications.", "content": "Stramonium poisoning; a diagnostic problem with psychiatric implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002149"}
{"pmid": "21002140", "title": "Parents' attitudes on child behavior; a report of three studies.", "content": "Parents' attitudes on child behavior; a report of three studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002140"}
{"pmid": "21002139", "title": "Child development in relation to community social structure.", "content": "Child development in relation to community social structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002139"}
{"pmid": "21002151", "title": "Newer agents in the treatment of epilepsy.", "content": "Newer agents in the treatment of epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002151"}
{"pmid": "21002150", "title": "Attempts to adapt murine poliomyelitis virus to the chick.", "content": "Attempts to adapt murine poliomyelitis virus to the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002150"}
{"pmid": "21002152", "title": "Immunization against whooping cough.", "content": "Immunization against whooping cough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002152"}
{"pmid": "21002153", "title": "Idiopathic lipemia.", "content": "Idiopathic lipemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002153"}
{"pmid": "21002154", "title": "A practical device to hold the nursing bottle during bottle feeding.", "content": "A practical device to hold the nursing bottle during bottle feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002154"}
{"pmid": "21002155", "title": "Russian public health and Soviet medicine.", "content": "Russian public health and Soviet medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002155"}
{"pmid": "21002156", "title": "Histoplasmin sensitivity.", "content": "Histoplasmin sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002156"}
{"pmid": "21002157", "title": "Electrophoretic patterns of blood sera in poliomyelitis and Guillain-Barré's disease (encephalomyeloradiculitis).", "content": "Electrophoretic patterns of blood sera in poliomyelitis and Guillain-Barré's disease (encephalomyeloradiculitis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002157"}
{"pmid": "21002158", "title": "The baby grid; an application of the grid technique to growth and development in infants.", "content": "The baby grid; an application of the grid technique to growth and development in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002158"}
{"pmid": "21002159", "title": "The effect of diabetic and prediabetic pregnancies on the fetus and newborn infant.", "content": "The effect of diabetic and prediabetic pregnancies on the fetus and newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002159"}
{"pmid": "21002160", "title": "Kernicterus in erythroblastosis fetalis.", "content": "Kernicterus in erythroblastosis fetalis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002160"}
{"pmid": "21002161", "title": "The importance of chronologic records in the management of allergic children.", "content": "The importance of chronologic records in the management of allergic children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002161"}
{"pmid": "21002162", "title": "Nonrachitic bowlegs in childhood; osteochondrosis deformans tibiae.", "content": "Nonrachitic bowlegs in childhood; osteochondrosis deformans tibiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002162"}
{"pmid": "21002163", "title": "Influenza virus vaccine; local and systemic reactions in children.", "content": "Influenza virus vaccine; local and systemic reactions in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002163"}
{"pmid": "21002164", "title": "Immune response to early administration of pertussis vaccine.", "content": "Immune response to early administration of pertussis vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002164"}
{"pmid": "21002165", "title": "Parapertussis pneumonia.", "content": "Parapertussis pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002165"}
{"pmid": "21002167", "title": "Erythroblastic anemia of Cooley; observations on the effect of splenectomy performed on identical twins.", "content": "Erythroblastic anemia of Cooley; observations on the effect of splenectomy performed on identical twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002167"}
{"pmid": "21002166", "title": "Mistreatment of congenital hemolytic disease (erythroblastosis fetalis) by transfusions of Rh-positive blood and maternal serum; a case report.", "content": "Mistreatment of congenital hemolytic disease (erythroblastosis fetalis) by transfusions of Rh-positive blood and maternal serum; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002166"}
{"pmid": "21002168", "title": "Erythema multiforme; with special emphasis on postvaccinal erythema.", "content": "Erythema multiforme; with special emphasis on postvaccinal erythema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002168"}
{"pmid": "21002169", "title": "A case of erythroblastosis fetalis caused by isoimmunization with the agglutinogen B.", "content": "A case of erythroblastosis fetalis caused by isoimmunization with the agglutinogen B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002169"}
{"pmid": "21002170", "title": "Transfusion of very small infants utilizing pneumatic pressure.", "content": "Transfusion of very small infants utilizing pneumatic pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002170"}
{"pmid": "21002171", "title": "The Academy Study of Child Health Services; the second year of the study begins with two campaigns ahead.", "content": "The Academy Study of Child Health Services; the second year of the study begins with two campaigns ahead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002171"}
{"pmid": "21002172", "title": "Compulsory prepaid medical care.", "content": "Compulsory prepaid medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002172"}
{"pmid": "21002173", "title": "Giant hydronephrosis as a cause of pyonephrosis in the opposite kidney: report of a case.", "content": "Giant hydronephrosis as a cause of pyonephrosis in the opposite kidney: report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002173"}
{"pmid": "21002174", "title": "Wilms's tumor in a horseshoe kidney.", "content": "Wilms's tumor in a horseshoe kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002174"}
{"pmid": "21002176", "title": "Hypoplasia of the ureter with renal agenesis.", "content": "Hypoplasia of the ureter with renal agenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002176"}
{"pmid": "21002175", "title": "Postcaval ureter; report of surgical case.", "content": "Postcaval ureter; report of surgical case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002175"}
{"pmid": "21002177", "title": "Acute interstitial cystitis; a clinical entity.", "content": "Acute interstitial cystitis; a clinical entity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002177"}
{"pmid": "21002178", "title": "Priapism complicating sickle cell anemia; a case report.", "content": "Priapism complicating sickle cell anemia; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002178"}
{"pmid": "21002179", "title": "Actinomycosis of the testicle.", "content": "Actinomycosis of the testicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002179"}
{"pmid": "21002180", "title": "Mumps orchitis; surgical treatment.", "content": "Mumps orchitis; surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002180"}
{"pmid": "21002181", "title": "Late effects of battle wounds in the genito-urinary tract.", "content": "Late effects of battle wounds in the genito-urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002181"}
{"pmid": "21002182", "title": "Study of fifty cases of enuresis.", "content": "Study of fifty cases of enuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002182"}
{"pmid": "21002183", "title": "Grain mite infestation of the urinary tract; report of three cases.", "content": "Grain mite infestation of the urinary tract; report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002183"}
{"pmid": "21002184", "title": "Oral penicillin in the treatment of neisserian infections.", "content": "Oral penicillin in the treatment of neisserian infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002184"}
{"pmid": "21002185", "title": "Sulfathiazole anuria with recovery following renal decapsulation.", "content": "Sulfathiazole anuria with recovery following renal decapsulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002185"}
{"pmid": "21002186", "title": "The advantages of cotton as a suture material in urological surgery.", "content": "The advantages of cotton as a suture material in urological surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002186"}
{"pmid": "21002187", "title": "The proven ineffectiveness of the compression bag in intravenous pyelography.", "content": "The proven ineffectiveness of the compression bag in intravenous pyelography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002187"}
{"pmid": "21002188", "title": "Urinary extravasation.", "content": "Urinary extravasation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002188"}
{"pmid": "21002189", "title": "Lymphogranuloma venereum; report of a case in a child.", "content": "Lymphogranuloma venereum; report of a case in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002189"}
{"pmid": "21002190", "title": "Ectopic pelvic kidney; report of a case with a huge hydronephrosis.", "content": "Ectopic pelvic kidney; report of a case with a huge hydronephrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002190"}
{"pmid": "21002191", "title": "Unusual renal obstruction following trauma.", "content": "Unusual renal obstruction following trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002191"}
{"pmid": "21002192", "title": "Thromboangitis, phlebitis and lymphangitis of the spermatic cord in relation to lymphogranuloma venereum.", "content": "Thromboangitis, phlebitis and lymphangitis of the spermatic cord in relation to lymphogranuloma venereum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002192"}
{"pmid": "21002193", "title": "Male infertility.", "content": "Male infertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002193"}
{"pmid": "21002194", "title": "Malignancies of the urinary tract; a five year survey with a report of an unusual case.", "content": "Malignancies of the urinary tract; a five year survey with a report of an unusual case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002194"}
{"pmid": "21002195", "title": "What part does posture play in ischemia and statis of the pelvic organs? description of fatigue by tests, and report of cases.", "content": "What part does posture play in ischemia and statis of the pelvic organs? description of fatigue by tests, and report of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002195"}
{"pmid": "21002196", "title": "Treatment of the dermatophytid.", "content": "Treatment of the dermatophytid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002196"}
{"pmid": "21002197", "title": "Epidermolysis bullosa hereditaria.", "content": "Epidermolysis bullosa hereditaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002197"}
{"pmid": "21002198", "title": "Metaplasia in the sex organs of castrated male sheep maintained on early subterranean clover pastures.", "content": "Metaplasia in the sex organs of castrated male sheep maintained on early subterranean clover pastures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002198"}
{"pmid": "21002199", "title": "Experimental observations on the efficiency and economics of rations for drought feeding of sheep.", "content": "Experimental observations on the efficiency and economics of rations for drought feeding of sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002199"}
{"pmid": "21002200", "title": "A survey of Victorian canine and vulpine parasites; Nematoda.", "content": "A survey of Victorian canine and vulpine parasites; Nematoda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002200"}
{"pmid": "21002201", "title": "Studies on the etiology of phalaris staggers in sheep; a preliminary report.", "content": "Studies on the etiology of phalaris staggers in sheep; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002201"}
{"pmid": "21002202", "title": "Protein substitutes for ruminants.", "content": "Protein substitutes for ruminants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002202"}
{"pmid": "21002203", "title": "The recent outbreak of swine fever in N. S. W.", "content": "The recent outbreak of swine fever in N. S. W.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002203"}
{"pmid": "21002204", "title": "The part played by animal transport in crossing the Gothic Line.", "content": "The part played by animal transport in crossing the Gothic Line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002204"}
{"pmid": "21002205", "title": "The surgical treatment of chronic scarred backs in pack animals.", "content": "The surgical treatment of chronic scarred backs in pack animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002205"}
{"pmid": "21002206", "title": "A newly developed anaesthetic for horses.", "content": "A newly developed anaesthetic for horses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002206"}
{"pmid": "21002207", "title": "Racing and breeding.", "content": "Racing and breeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002207"}
{"pmid": "21002208", "title": "Acute piroplasmosis.", "content": "Acute piroplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002208"}
{"pmid": "21002209", "title": "Shoeing in the field.", "content": "Shoeing in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002209"}
{"pmid": "21002210", "title": "The synthesis of estradiol and l-methylestradiol from cholesterol.", "content": "The synthesis of estradiol and l-methylestradiol from cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002210"}
{"pmid": "21002211", "title": "Anomalous orientation in a Friedel-Crafts ketone synthesis.", "content": "Anomalous orientation in a Friedel-Crafts ketone synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002211"}
{"pmid": "21002212", "title": "Synthesis of maltose-l-phosphate and d-xylose-l-phosphate.", "content": "Synthesis of maltose-l-phosphate and d-xylose-l-phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002212"}
{"pmid": "21002213", "title": "The ultraviolet absorption spectra of thiouracils.", "content": "The ultraviolet absorption spectra of thiouracils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002213"}
{"pmid": "21002214", "title": "A new type of precision capillarimeter.", "content": "A new type of precision capillarimeter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002214"}
{"pmid": "21002215", "title": "Derivatives of 2-amino-4-methylthiazole.", "content": "Derivatives of 2-amino-4-methylthiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002215"}
{"pmid": "21002216", "title": "5-R-thiomethyl- and 5-R-sulfonylmethyl-5-phenylhydantoins.", "content": "5-R-thiomethyl- and 5-R-sulfonylmethyl-5-phenylhydantoins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002216"}
{"pmid": "21002217", "title": "Cis and trans di-equilenane.", "content": "Cis and trans di-equilenane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002217"}
{"pmid": "21002218", "title": "Dihydrostreptomycin.", "content": "Dihydrostreptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002218"}
{"pmid": "21002219", "title": "Synthetic analogs of the adrenal cortical hormones.", "content": "Synthetic analogs of the adrenal cortical hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002219"}
{"pmid": "21002221", "title": "Isosucrose synthesis.", "content": "Isosucrose synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002221"}
{"pmid": "21002220", "title": "Chromatography of sugars and their derivatives.", "content": "Chromatography of sugars and their derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002220"}
{"pmid": "21002222", "title": "Analgesics; n-alkylated-1,2-diphenylethylamines prepared by the Leuckart reaction.", "content": "Analgesics; n-alkylated-1,2-diphenylethylamines prepared by the Leuckart reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002222"}
{"pmid": "21002223", "title": "Steric effect of methylene groups.", "content": "Steric effect of methylene groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002223"}
{"pmid": "21002225", "title": "Absorption spectra of heterocyclic compounds; quinolinols and isoquinolinols.", "content": "Absorption spectra of heterocyclic compounds; quinolinols and isoquinolinols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002225"}
{"pmid": "21002224", "title": "The Browning (Maillard) reaction in heated solutions of uronic acids.", "content": "The Browning (Maillard) reaction in heated solutions of uronic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002224"}
{"pmid": "21002226", "title": "8-Aminoquinolines with allylamine substituents.", "content": "8-Aminoquinolines with allylamine substituents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002226"}
{"pmid": "21002227", "title": "Tetrahydrothiophene (thiophane) derivatives.", "content": "Tetrahydrothiophene (thiophane) derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002227"}
{"pmid": "21002228", "title": "The preparation of some 9-diethylaminoalkylphenazines.", "content": "The preparation of some 9-diethylaminoalkylphenazines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002228"}
{"pmid": "21002229", "title": "A further study of the porphine-like products of the reaction of benzaldehyde and pyrrole.", "content": "A further study of the porphine-like products of the reaction of benzaldehyde and pyrrole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002229"}
{"pmid": "21002230", "title": "Spectrophotometric investigations of the interactions of proteins with organic anions.", "content": "Spectrophotometric investigations of the interactions of proteins with organic anions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002230"}
{"pmid": "21002231", "title": "Physical chemistry of protein solutions; derivation of the equations for the osmotic pressure.", "content": "Physical chemistry of protein solutions; derivation of the equations for the osmotic pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002231"}
{"pmid": "21002232", "title": "Preparation and properties of serum and plasma proteins; osmotic equilibria in solutions of serum albumin and sodium chloride.", "content": "Preparation and properties of serum and plasma proteins; osmotic equilibria in solutions of serum albumin and sodium chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002232"}
{"pmid": "21002233", "title": "alpha-Methylene butyrolactone from Erythronium americanum.", "content": "alpha-Methylene butyrolactone from Erythronium americanum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002233"}
{"pmid": "21002234", "title": "Studies on the Wilgerodt reaction; the preparation of nuclear-substituted phenylacetic acids and some further extensions of the reaction.", "content": "Studies on the Wilgerodt reaction; the preparation of nuclear-substituted phenylacetic acids and some further extensions of the reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002234"}
{"pmid": "21002235", "title": "Sugar interconversion under reducing conditions; d,1-glucitol.", "content": "Sugar interconversion under reducing conditions; d,1-glucitol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002235"}
{"pmid": "21002236", "title": "N-methyl-1-glucosaminic acid.", "content": "N-methyl-1-glucosaminic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002236"}
{"pmid": "21002237", "title": "Antispasmodics; derivatives of 1-phenylcycloparaffin-carboxylic acids.", "content": "Antispasmodics; derivatives of 1-phenylcycloparaffin-carboxylic acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002237"}
{"pmid": "21002238", "title": "Studies in the imidazolone series; the synthesis of a lower and a higher homolog of desthiobiotin and of related substances.", "content": "Studies in the imidazolone series; the synthesis of a lower and a higher homolog of desthiobiotin and of related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002238"}
{"pmid": "21002239", "title": "Analogs of pyridoxine; some hydroxymethylpyrimidine derivatives.", "content": "Analogs of pyridoxine; some hydroxymethylpyrimidine derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002239"}
{"pmid": "21002240", "title": "Analogs of pyridoxine; synthesis of a pyrimidine analog.", "content": "Analogs of pyridoxine; synthesis of a pyrimidine analog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002240"}
{"pmid": "21002241", "title": "Some 4-amino-quinoline and 9-aminoacridine derivatives.", "content": "Some 4-amino-quinoline and 9-aminoacridine derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002241"}
{"pmid": "21002242", "title": "Catalytic decomposition of DDT.", "content": "Catalytic decomposition of DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002242"}
{"pmid": "21002243", "title": "Antitubercular studies; bis-(p-aminophenyl) derivatives of ethyl ether and trichloroethane.", "content": "Antitubercular studies; bis-(p-aminophenyl) derivatives of ethyl ether and trichloroethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002243"}
{"pmid": "21002244", "title": "The conjugation of peptides with 1,2-benzanthryl-10-isocyanate.", "content": "The conjugation of peptides with 1,2-benzanthryl-10-isocyanate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002244"}
{"pmid": "21002245", "title": "Ultraviolet absorption spectra of mescaline sulfate and betaphenylethylamine sulfate.", "content": "Ultraviolet absorption spectra of mescaline sulfate and betaphenylethylamine sulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002245"}
{"pmid": "21002246", "title": "The antitubercular action of 1,1,1-trichloro-2,2-bis-(p-aminophenyl)-ethane.", "content": "The antitubercular action of 1,1,1-trichloro-2,2-bis-(p-aminophenyl)-ethane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002246"}
{"pmid": "21002247", "title": "A chemical assay method for penicillin G.", "content": "A chemical assay method for penicillin G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002247"}
{"pmid": "21002248", "title": "Gnathostatic diagnosis.", "content": "Gnathostatic diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002248"}
{"pmid": "21002249", "title": "Management of class II, division 2 (Angle) malocclusions.", "content": "Management of class II, division 2 (Angle) malocclusions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002249"}
{"pmid": "21002250", "title": "A method for recording the key ridge.", "content": "A method for recording the key ridge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002250"}
{"pmid": "21002251", "title": "The face and its development; anomalies of occlusion and the trend to beautify the features.", "content": "The face and its development; anomalies of occlusion and the trend to beautify the features.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002251"}
{"pmid": "21002252", "title": "School dental health service in Tel-Aviv.", "content": "School dental health service in Tel-Aviv.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002252"}
{"pmid": "21002253", "title": "The responsibility of public health agencies to cleft palate patients.", "content": "The responsibility of public health agencies to cleft palate patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002253"}
{"pmid": "21002254", "title": "The responsibility of the surgeon in treating palatal and related defects.", "content": "The responsibility of the surgeon in treating palatal and related defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002254"}
{"pmid": "21002255", "title": "Present status of surgical treatment of cleft hard palate.", "content": "Present status of surgical treatment of cleft hard palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002255"}
{"pmid": "21002256", "title": "Surgical treatment of vicious cicatrices involving the cheek, lip, and alveolar process in cleft lip and palate cases.", "content": "Surgical treatment of vicious cicatrices involving the cheek, lip, and alveolar process in cleft lip and palate cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002256"}
{"pmid": "21002257", "title": "The responsibility of the orthodontist in the cleft palate problem.", "content": "The responsibility of the orthodontist in the cleft palate problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002257"}
{"pmid": "21002258", "title": "The responsibility of the prosthodontist in the treatment of the cleft palate patient.", "content": "The responsibility of the prosthodontist in the treatment of the cleft palate patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002258"}
{"pmid": "21002259", "title": "Obturator of choice for congenital cleft palate.", "content": "Obturator of choice for congenital cleft palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002259"}
{"pmid": "21002260", "title": "The responsibility of the speech correctionist in the treatment of the cleft palate patient who has received surgical or prosthetic treatment.", "content": "The responsibility of the speech correctionist in the treatment of the cleft palate patient who has received surgical or prosthetic treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002260"}
{"pmid": "21002261", "title": "Present status of speech training of patients who wear speech correction appliances.", "content": "Present status of speech training of patients who wear speech correction appliances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002261"}
{"pmid": "21002262", "title": "A technique to split teeth.", "content": "A technique to split teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002262"}
{"pmid": "21002263", "title": "Attempted suicide with gunshot through the mouth; unexpected location of the projectile.", "content": "Attempted suicide with gunshot through the mouth; unexpected location of the projectile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002263"}
{"pmid": "21002265", "title": "Correlation of active and passive eruption.", "content": "Correlation of active and passive eruption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002265"}
{"pmid": "21002266", "title": "Face pain.", "content": "Face pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002266"}
{"pmid": "21002264", "title": "The biology of dentin.", "content": "The biology of dentin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002264"}
{"pmid": "21002267", "title": "Osteomyelitis of the jaws.", "content": "Osteomyelitis of the jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002267"}
{"pmid": "21002268", "title": "Nitrous oxide-oxygen anesthesia.", "content": "Nitrous oxide-oxygen anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002268"}
{"pmid": "21002269", "title": "Case report of a fracture reduction by vitallium screws.", "content": "Case report of a fracture reduction by vitallium screws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002269"}
{"pmid": "21002270", "title": "Local anesthesia armamentarium and its care.", "content": "Local anesthesia armamentarium and its care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002270"}
{"pmid": "21002271", "title": "Home-made celluloid crown forms.", "content": "Home-made celluloid crown forms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002271"}
{"pmid": "21002272", "title": "Selection of treatment for periodontal disease.", "content": "Selection of treatment for periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002272"}
{"pmid": "21002273", "title": "Acquired maxillary protrusion; case reports.", "content": "Acquired maxillary protrusion; case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002273"}
{"pmid": "21002274", "title": "Constructing acrylic resin jacket crowns.", "content": "Constructing acrylic resin jacket crowns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002274"}
{"pmid": "21002275", "title": "The spread of infections in the floor of the mouth.", "content": "The spread of infections in the floor of the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002275"}
{"pmid": "21002276", "title": "Construction of palateless full upper dentures.", "content": "Construction of palateless full upper dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002276"}
{"pmid": "21002277", "title": "Pemphigus vulgaris; a systemic disease; early symptoms of importance to the dentist.", "content": "Pemphigus vulgaris; a systemic disease; early symptoms of importance to the dentist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002277"}
{"pmid": "21002278", "title": "Preoperative considerations in dental surgery for the chronically ill; a physician's viewpoint.", "content": "Preoperative considerations in dental surgery for the chronically ill; a physician's viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002278"}
{"pmid": "21002279", "title": "Responsibility of general practitioner and oral surgeon in the care of their patients.", "content": "Responsibility of general practitioner and oral surgeon in the care of their patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002279"}
{"pmid": "21002280", "title": "Hematological problems in dental and oral surgery.", "content": "Hematological problems in dental and oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002280"}
{"pmid": "21002281", "title": "Penicillin and its use in dentistry.", "content": "Penicillin and its use in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002281"}
{"pmid": "21002282", "title": "BASIC standards of hospital dental service required of approved hospitals by Committee on Hospital Dental Service of the American Dental Association.", "content": "BASIC standards of hospital dental service required of approved hospitals by Committee on Hospital Dental Service of the American Dental Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002282"}
{"pmid": "21002283", "title": "The effect of hard candy and carbonated beverages on tooth structure.", "content": "The effect of hard candy and carbonated beverages on tooth structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002283"}
{"pmid": "21002284", "title": "Penicillin in dentistry.", "content": "Penicillin in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002284"}
{"pmid": "21002285", "title": "Nutritional factors affecting wound healing.", "content": "Nutritional factors affecting wound healing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002285"}
{"pmid": "21002286", "title": "Some histological effects of partial deficiency of vitamin C on healing processes; the influence on phosphatase formation in experimental skin wounds.", "content": "Some histological effects of partial deficiency of vitamin C on healing processes; the influence on phosphatase formation in experimental skin wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002286"}
{"pmid": "21002287", "title": "Some histological effects of partial deficiency of vitamin C on healing processes; the influence on bone repair.", "content": "Some histological effects of partial deficiency of vitamin C on healing processes; the influence on bone repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002287"}
{"pmid": "21002288", "title": "The effect of vitamin C on the healing of wounds.", "content": "The effect of vitamin C on the healing of wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002288"}
{"pmid": "21002289", "title": "The quality of proteins.", "content": "The quality of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002289"}
{"pmid": "21002290", "title": "The essential amino-acids.", "content": "The essential amino-acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002290"}
{"pmid": "21002291", "title": "The therapeutic use of protein hydrolysates.", "content": "The therapeutic use of protein hydrolysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002291"}
{"pmid": "21002292", "title": "Use of isotopic tracers in the study of protein metabolism.", "content": "Use of isotopic tracers in the study of protein metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002292"}
{"pmid": "21002293", "title": "Modern methods of studying protein metabolism.", "content": "Modern methods of studying protein metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002293"}
{"pmid": "21002294", "title": "The training of dieticians; the current position.", "content": "The training of dieticians; the current position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002294"}
{"pmid": "21002295", "title": "The function of dieticians and their role in the future.", "content": "The function of dieticians and their role in the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002295"}
{"pmid": "21002296", "title": "The function of dieticians and their role in the future with special reference to the United States and Canada.", "content": "The function of dieticians and their role in the future with special reference to the United States and Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002296"}
{"pmid": "21002297", "title": "The dietician in the public health service.", "content": "The dietician in the public health service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002297"}
{"pmid": "21002298", "title": "The dietician in schools.", "content": "The dietician in schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002298"}
{"pmid": "21002299", "title": "The dietician in industry.", "content": "The dietician in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002299"}
{"pmid": "21002300", "title": "The dietician in hospitals.", "content": "The dietician in hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002300"}
{"pmid": "21002304", "title": "The relationship of medical practice to gerontology.", "content": "The relationship of medical practice to gerontology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002304"}
{"pmid": "21002305", "title": "Splenectomy for patients past sixty.", "content": "Splenectomy for patients past sixty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002305"}
{"pmid": "21002306", "title": "Selective placement of older workers.", "content": "Selective placement of older workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002306"}
{"pmid": "21002307", "title": "The effects of androsterone, oestradiol, and thyroid hormone on the artificial premature climacteric of pure gonadal origin produced by ovariectomy in rats; effects on weights of organs.", "content": "The effects of androsterone, oestradiol, and thyroid hormone on the artificial premature climacteric of pure gonadal origin produced by ovariectomy in rats; effects on weights of organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002307"}
{"pmid": "21002309", "title": "Histochemical changes associated with aging; liver, brain, and kidney in the rat.", "content": "Histochemical changes associated with aging; liver, brain, and kidney in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002309"}
{"pmid": "21002308", "title": "The effects of androsterone, oestradiol, and thyroid hormone on the artificial premature climacteric of pure gonadal origin produced by ovariectomy in rats; effects on histologic structure of liver and kidneys.", "content": "The effects of androsterone, oestradiol, and thyroid hormone on the artificial premature climacteric of pure gonadal origin produced by ovariectomy in rats; effects on histologic structure of liver and kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002308"}
{"pmid": "21002310", "title": "Age and infection; a review.", "content": "Age and infection; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002310"}
{"pmid": "21002311", "title": "British national health insurance; the workers' pride.", "content": "British national health insurance; the workers' pride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002311"}
{"pmid": "21002312", "title": "The superiority of the South African Negro or Bantu as a parturient.", "content": "The superiority of the South African Negro or Bantu as a parturient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002312"}
{"pmid": "21002301", "title": "Society and the criminal.", "content": "Society and the criminal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002301"}
{"pmid": "21002313", "title": "The blood in pregnancy; the haemoglobin level.", "content": "The blood in pregnancy; the haemoglobin level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002313"}
{"pmid": "21002315", "title": "Primary carcinoma of the Fallopian tube; a report of four cases.", "content": "Primary carcinoma of the Fallopian tube; a report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002315"}
{"pmid": "21002314", "title": "Stillbirth and neonatal death; a clinico-pathological study.", "content": "Stillbirth and neonatal death; a clinico-pathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002314"}
{"pmid": "21002303", "title": "Early days of the Medico-legal Society.", "content": "Early days of the Medico-legal Society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002303"}
{"pmid": "21002302", "title": "Individuality and identity.", "content": "Individuality and identity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002302"}
{"pmid": "21002316", "title": "Weather changes and eclampsia.", "content": "Weather changes and eclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002316"}
{"pmid": "21002317", "title": "Preservation of normal human plasma in the liquid state; clinical, chemical, and physicochemical studies during three years of storage at room temperature.", "content": "Preservation of normal human plasma in the liquid state; clinical, chemical, and physicochemical studies during three years of storage at room temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002317"}
{"pmid": "21002318", "title": "Platelet counts and platelet function.", "content": "Platelet counts and platelet function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002318"}
{"pmid": "21002319", "title": "Pseudohemophilia; case study.", "content": "Pseudohemophilia; case study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002319"}
{"pmid": "21002320", "title": "Pseudohemophilia.", "content": "Pseudohemophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002320"}
{"pmid": "21002321", "title": "On the influence of stilbamidine upon myeloma cells.", "content": "On the influence of stilbamidine upon myeloma cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002321"}
{"pmid": "21002322", "title": "Hematological changes following the administration of large doses of quinacrine hydrochloride.", "content": "Hematological changes following the administration of large doses of quinacrine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002322"}
{"pmid": "21002323", "title": "Specificity of isoagglutinin response following injection of group substances into group O individuals.", "content": "Specificity of isoagglutinin response following injection of group substances into group O individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002323"}
{"pmid": "21002324", "title": "The blood groups, subgroups, and Rh factor of the Mapuche Indians of the Province of Cautin, Chile.", "content": "The blood groups, subgroups, and Rh factor of the Mapuche Indians of the Province of Cautin, Chile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002324"}
{"pmid": "21002325", "title": "Sacroiliac syndrome.", "content": "Sacroiliac syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002325"}
{"pmid": "21002326", "title": "A report on the use of the African clawed frog (Xenopus laevis Daudin) for early diagnosis of pregnancy.", "content": "A report on the use of the African clawed frog (Xenopus laevis Daudin) for early diagnosis of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002326"}
{"pmid": "21002327", "title": "An evaluation of routine cephalopelvimetry of sixty white primiparas.", "content": "An evaluation of routine cephalopelvimetry of sixty white primiparas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002327"}
{"pmid": "21002328", "title": "Undulant fever and the public health.", "content": "Undulant fever and the public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002328"}
{"pmid": "21002329", "title": "The treatment of subacute bacterial endocarditis.", "content": "The treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002329"}
{"pmid": "21002330", "title": "Posture and its relation to anorectal disease.", "content": "Posture and its relation to anorectal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002330"}
{"pmid": "21002331", "title": "Adenomata of the rectosigmoid region.", "content": "Adenomata of the rectosigmoid region.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002331"}
{"pmid": "21002332", "title": "Proctology, a modern concept.", "content": "Proctology, a modern concept.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002332"}
{"pmid": "21002333", "title": "Evaluating cryptitis as fundamental rectal pathology.", "content": "Evaluating cryptitis as fundamental rectal pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002333"}
{"pmid": "21002334", "title": "Control of pain in proctologic surgery.", "content": "Control of pain in proctologic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002334"}
{"pmid": "21002337", "title": "Importance of the pectinate line.", "content": "Importance of the pectinate line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002337"}
{"pmid": "21002335", "title": "Postoperative hemorrhage in proctology.", "content": "Postoperative hemorrhage in proctology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002335"}
{"pmid": "21002336", "title": "A method of anal anesthesia.", "content": "A method of anal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002336"}
{"pmid": "21002340", "title": "Establishing a psychiatric department in a general hospital; how it began, how it developed, personnel, treatment and a look into the future.", "content": "Establishing a psychiatric department in a general hospital; how it began, how it developed, personnel, treatment and a look into the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002340"}
{"pmid": "21002341", "title": "NEW 150-bed, four-story hospital incorporates new features; air conditioning, radiant floor heat, germicidal lamps, oxygen pipes at St. Benedict's, Ogden, Utah.", "content": "NEW 150-bed, four-story hospital incorporates new features; air conditioning, radiant floor heat, germicidal lamps, oxygen pipes at St. Benedict's, Ogden, Utah.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002341"}
{"pmid": "21002342", "title": "How to cut building, operating costs; employ hospital consultant; proper planning can head off overbuilding; proper design can bring permanent economies.", "content": "How to cut building, operating costs; employ hospital consultant; proper planning can head off overbuilding; proper design can bring permanent economies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002342"}
{"pmid": "21002343", "title": "Compulsion; the key to collectivism; a guidebook to W-M-D guile; how sponsors of compulsory health sought verdict with packed panel.", "content": "Compulsion; the key to collectivism; a guidebook to W-M-D guile; how sponsors of compulsory health sought verdict with packed panel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002343"}
{"pmid": "21002347", "title": "The value of plant inspections when made by the plant physician with the safety director.", "content": "The value of plant inspections when made by the plant physician with the safety director.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002347"}
{"pmid": "21002345", "title": "The newer uses of topical penicillin; in the treatment of dermatologic infections.", "content": "The newer uses of topical penicillin; in the treatment of dermatologic infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002345"}
{"pmid": "21002344", "title": "The necessity for having a definite schedule for periodic re-examination of all employees including salaried group and management group.", "content": "The necessity for having a definite schedule for periodic re-examination of all employees including salaried group and management group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002344"}
{"pmid": "21002346", "title": "Trauma and disease.", "content": "Trauma and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002346"}
{"pmid": "21002348", "title": "Wound healing and early ambulation.", "content": "Wound healing and early ambulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002348"}
{"pmid": "21002349", "title": "Medicine and research.", "content": "Medicine and research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002349"}
{"pmid": "21002350", "title": "Placing the handicapped; a positive, individual and specific approach.", "content": "Placing the handicapped; a positive, individual and specific approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002350"}
{"pmid": "21002351", "title": "Better use of laboratory procedures; for more accurate diagnosis in industrial medicine.", "content": "Better use of laboratory procedures; for more accurate diagnosis in industrial medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002351"}
{"pmid": "21002352", "title": "Principles of acknowledging compensation claims for arthritis.", "content": "Principles of acknowledging compensation claims for arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002352"}
{"pmid": "21002353", "title": "The role of the laboratory; in an industrial hygiene program.", "content": "The role of the laboratory; in an industrial hygiene program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002353"}
{"pmid": "21002354", "title": "Dysmenorrhea in industry; treatment with a new antispasmodic.", "content": "Dysmenorrhea in industry; treatment with a new antispasmodic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002354"}
{"pmid": "21002355", "title": "A case of byssinosis.", "content": "A case of byssinosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002355"}
{"pmid": "21002356", "title": "Edema.", "content": "Edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002356"}
{"pmid": "21002357", "title": "The silent values in industrial health.", "content": "The silent values in industrial health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002357"}
{"pmid": "21002358", "title": "Physical capacities appraisal; of the industrial back.", "content": "Physical capacities appraisal; of the industrial back.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002358"}
{"pmid": "21002359", "title": "TREATMENT of respiratory depression and asphyxia.", "content": "TREATMENT of respiratory depression and asphyxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002359"}
{"pmid": "21002360", "title": "Backache.", "content": "Backache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002360"}
{"pmid": "21002362", "title": "Evaluation of the beta and gamma radiation due to extended linear sources of radium.", "content": "Evaluation of the beta and gamma radiation due to extended linear sources of radium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002362"}
{"pmid": "21002363", "title": "The determination of mercury in air.", "content": "The determination of mercury in air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002363"}
{"pmid": "21002364", "title": "Further studies on sensory response to certain industrial solvent vapors.", "content": "Further studies on sensory response to certain industrial solvent vapors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002364"}
{"pmid": "21002365", "title": "A case of fatal poisoning from 2-methoxy-ethanol.", "content": "A case of fatal poisoning from 2-methoxy-ethanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002365"}
{"pmid": "21002366", "title": "A modified cascade impactor; a device for sampling and sizing aerosols of particles below one micron in diameter.", "content": "A modified cascade impactor; a device for sampling and sizing aerosols of particles below one micron in diameter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002366"}
{"pmid": "21002367", "title": "An apparatus for dispersing finely divided dusts.", "content": "An apparatus for dispersing finely divided dusts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002367"}
{"pmid": "21002368", "title": "Estimation of sulfur compounds in air.", "content": "Estimation of sulfur compounds in air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002368"}
{"pmid": "21002370", "title": "The hospital survey and construction act.", "content": "The hospital survey and construction act.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002370"}
{"pmid": "21002369", "title": "An industrial hygiene survey of an onion dehydrating plant.", "content": "An industrial hygiene survey of an onion dehydrating plant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002369"}
{"pmid": "21002361", "title": "The medical rehabilitation of the disabled.", "content": "The medical rehabilitation of the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002361"}
{"pmid": "21002371", "title": "WORLD Health Organization.", "content": "WORLD Health Organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002371"}
{"pmid": "21002377", "title": "Far Eastern tick-borne spring-summer (spring) encephalitis.", "content": "Far Eastern tick-borne spring-summer (spring) encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002377"}
{"pmid": "21002393", "title": "Climacteric, male and female.", "content": "Climacteric, male and female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002393"}
{"pmid": "21002394", "title": "Pregnancy complicating diabetes.", "content": "Pregnancy complicating diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002394"}
{"pmid": "21002395", "title": "Tropical diseases.", "content": "Tropical diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002395"}
{"pmid": "21002396", "title": "The extension of radical surgery in the treatment of cancer.", "content": "The extension of radical surgery in the treatment of cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002396"}
{"pmid": "21002397", "title": "Nazi war crimes of a medical nature.", "content": "Nazi war crimes of a medical nature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002397"}
{"pmid": "21002398", "title": "Acute pancreatitis; diagnosis and treatment with brief review of cases at the Vancouver General Hospital in the last 7 years.", "content": "Acute pancreatitis; diagnosis and treatment with brief review of cases at the Vancouver General Hospital in the last 7 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002398"}
{"pmid": "21002399", "title": "Case of unusual mesenteric tumour.", "content": "Case of unusual mesenteric tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002399"}
{"pmid": "21002400", "title": "The evolution of our knowledge of the allergic diseases.", "content": "The evolution of our knowledge of the allergic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002400"}
{"pmid": "21002401", "title": "Allergy in relation to medical education.", "content": "Allergy in relation to medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002401"}
{"pmid": "21002402", "title": "Fundamental considerations of allergic reactions.", "content": "Fundamental considerations of allergic reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002402"}
{"pmid": "21002403", "title": "The pathology of asthma.", "content": "The pathology of asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002403"}
{"pmid": "21002404", "title": "Hay fever.", "content": "Hay fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002404"}
{"pmid": "21002405", "title": "Foods and their relation to allergy.", "content": "Foods and their relation to allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002405"}
{"pmid": "21002406", "title": "Allergic contact dermatitis.", "content": "Allergic contact dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002406"}
{"pmid": "21002407", "title": "Urticaria and angioneurotic edema.", "content": "Urticaria and angioneurotic edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002407"}
{"pmid": "21002408", "title": "Allergic rhinitis.", "content": "Allergic rhinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002408"}
{"pmid": "21002409", "title": "Vascular allergy.", "content": "Vascular allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002409"}
{"pmid": "21002410", "title": "Periodic vascular head pain; a discussion of the mechanism, clinical types and the roles of vasoconstricting and vasodilating drugs in the diagnosis and treatment.", "content": "Periodic vascular head pain; a discussion of the mechanism, clinical types and the roles of vasoconstricting and vasodilating drugs in the diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002410"}
{"pmid": "21002411", "title": "Drug allergy.", "content": "Drug allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002411"}
{"pmid": "21002412", "title": "Mold allergy.", "content": "Mold allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002412"}
{"pmid": "21002413", "title": "The determination of the total 17-ketosteroids in urine; a simplification of the method for routine use in a hospital biochemical laboratory.", "content": "The determination of the total 17-ketosteroids in urine; a simplification of the method for routine use in a hospital biochemical laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002413"}
{"pmid": "21002414", "title": "Intussusception of the appendix.", "content": "Intussusception of the appendix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002414"}
{"pmid": "21002415", "title": "Multiple carcinoid tumours of the bowel; report of a case.", "content": "Multiple carcinoid tumours of the bowel; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002415"}
{"pmid": "21002416", "title": "The concept of the general practitioner in the dental treatment of fractures of the jaw.", "content": "The concept of the general practitioner in the dental treatment of fractures of the jaw.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002416"}
{"pmid": "21002417", "title": "Physiological adaptations.", "content": "Physiological adaptations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002417"}
{"pmid": "21002418", "title": "An unusual uterine developmental defect.", "content": "An unusual uterine developmental defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002418"}
{"pmid": "21002419", "title": "Pathognomy at the bedside.", "content": "Pathognomy at the bedside.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002419"}
{"pmid": "21002420", "title": "Medical learning and medical language.", "content": "Medical learning and medical language.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002420"}
{"pmid": "21002421", "title": "Reconstructive surgery to the hand.", "content": "Reconstructive surgery to the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002421"}
{"pmid": "21002422", "title": "MUSHROOM poisoning in a diabetic.", "content": "MUSHROOM poisoning in a diabetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002422"}
{"pmid": "21002423", "title": "The management of persistent occiput posterior; with a note on the technic of forceps rotation by the Stillman procedure.", "content": "The management of persistent occiput posterior; with a note on the technic of forceps rotation by the Stillman procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002423"}
{"pmid": "21002424", "title": "Indications for antibiotics (penicillin and streptomycin) in urinary tract infections.", "content": "Indications for antibiotics (penicillin and streptomycin) in urinary tract infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002424"}
{"pmid": "21002425", "title": "Vocational rehabilitation in Illinois.", "content": "Vocational rehabilitation in Illinois.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002425"}
{"pmid": "21002426", "title": "Hazards in the use of sedatives; bromide intoxication.", "content": "Hazards in the use of sedatives; bromide intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002426"}
{"pmid": "21002427", "title": "Newer aspects in the treatment of liver diseases.", "content": "Newer aspects in the treatment of liver diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002427"}
{"pmid": "21002428", "title": "Establishing a modern plant medical program.", "content": "Establishing a modern plant medical program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002428"}
{"pmid": "21002429", "title": "A plea for a more conservative attitude in renal surgery.", "content": "A plea for a more conservative attitude in renal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002429"}
{"pmid": "21002430", "title": "Neurologic complications of spinal anesthesia.", "content": "Neurologic complications of spinal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002430"}
{"pmid": "21002431", "title": "Subdural hematoma.", "content": "Subdural hematoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002431"}
{"pmid": "21002432", "title": "The management of bacterial infections of the skin.", "content": "The management of bacterial infections of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002432"}
{"pmid": "21002433", "title": "New treatment for incompetent valves in varicose veins.", "content": "New treatment for incompetent valves in varicose veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002433"}
{"pmid": "21002434", "title": "Histamine and antihistaminic agents; their experimental and therapeutic status.", "content": "Histamine and antihistaminic agents; their experimental and therapeutic status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002434"}
{"pmid": "21002435", "title": "BRUTALITIES of Nazi physicians.", "content": "BRUTALITIES of Nazi physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002435"}
{"pmid": "21002436", "title": "New horizons in industrial health and welfare; progress in industrial health.", "content": "New horizons in industrial health and welfare; progress in industrial health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002436"}
{"pmid": "21002437", "title": "New horizons in industrial health and welfare; role of management in medical plans.", "content": "New horizons in industrial health and welfare; role of management in medical plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002437"}
{"pmid": "21002438", "title": "Horizons in industrial health and welfare; labor and management at the conference table.", "content": "Horizons in industrial health and welfare; labor and management at the conference table.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002438"}
{"pmid": "21002439", "title": "Blast injury.", "content": "Blast injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002439"}
{"pmid": "21002440", "title": "Accidents on the farm.", "content": "Accidents on the farm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002440"}
{"pmid": "21002441", "title": "Industrial ophthalmology as of 1946.", "content": "Industrial ophthalmology as of 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002441"}
{"pmid": "21002442", "title": "Treatment of tuberculosis with streptomycin; a summary of observations on one hundred cases.", "content": "Treatment of tuberculosis with streptomycin; a summary of observations on one hundred cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002442"}
{"pmid": "21002443", "title": "The principles of medical ethics.", "content": "The principles of medical ethics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002443"}
{"pmid": "21002444", "title": "Apparent sensitivity to amigen.", "content": "Apparent sensitivity to amigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002444"}
{"pmid": "21002445", "title": "RECOGNITION and treatment of carbon tetrachloride poisoning.", "content": "RECOGNITION and treatment of carbon tetrachloride poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002445"}
{"pmid": "21002446", "title": "The physician's responsibility in venereal disease control.", "content": "The physician's responsibility in venereal disease control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002446"}
{"pmid": "21002447", "title": "Vascular injuries due to cold with particular reference to the late phase of trench foot.", "content": "Vascular injuries due to cold with particular reference to the late phase of trench foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002447"}
{"pmid": "21002448", "title": "Powder penicillin; its surgical uses and advantages.", "content": "Powder penicillin; its surgical uses and advantages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002448"}
{"pmid": "21002449", "title": "The significance of soft tissue injuries.", "content": "The significance of soft tissue injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002449"}
{"pmid": "21002450", "title": "Infantile scurvy.", "content": "Infantile scurvy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002450"}
{"pmid": "21002451", "title": "Maternal mortality in Florida.", "content": "Maternal mortality in Florida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002451"}
{"pmid": "21002452", "title": "Indiana State Medical Association.", "content": "Indiana State Medical Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002452"}
{"pmid": "21002453", "title": "General reflections on geriatics.", "content": "General reflections on geriatics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002453"}
{"pmid": "21002454", "title": "Health guidance in advancing years.", "content": "Health guidance in advancing years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002454"}
{"pmid": "21002455", "title": "Certain aspects of geriatric medicine.", "content": "Certain aspects of geriatric medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002455"}
{"pmid": "21002456", "title": "Mental hygiene in geriatrics.", "content": "Mental hygiene in geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002456"}
{"pmid": "21002457", "title": "Arthritis.", "content": "Arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002457"}
{"pmid": "21002458", "title": "Cancer.", "content": "Cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002458"}
{"pmid": "21002459", "title": "Cardiovascular-renal diseases.", "content": "Cardiovascular-renal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002459"}
{"pmid": "21002460", "title": "Medical responsibility in industrial health.", "content": "Medical responsibility in industrial health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002460"}
{"pmid": "21002461", "title": "Management's responsibility in industrial health.", "content": "Management's responsibility in industrial health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002461"}
{"pmid": "21002462", "title": "Medical implications of atomic energy.", "content": "Medical implications of atomic energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002462"}
{"pmid": "21002463", "title": "Refrigeration in surgery.", "content": "Refrigeration in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002463"}
{"pmid": "21002464", "title": "The diagnosis and treatment of hyperparathyroidism.", "content": "The diagnosis and treatment of hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002464"}
{"pmid": "21002465", "title": "Problems of trauma.", "content": "Problems of trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002465"}
{"pmid": "21002466", "title": "General consideration of hysterectomy.", "content": "General consideration of hysterectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002466"}
{"pmid": "21002467", "title": "Erythema multiforme, with unusual manifestations.", "content": "Erythema multiforme, with unusual manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002467"}
{"pmid": "21002468", "title": "The value of the anteroposterior lordotic film of the chest.", "content": "The value of the anteroposterior lordotic film of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002468"}
{"pmid": "21002469", "title": "Fatigue states associated with endocrine disorders.", "content": "Fatigue states associated with endocrine disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002469"}
{"pmid": "21002470", "title": "Pioneer users of x-rays in Oklahoma.", "content": "Pioneer users of x-rays in Oklahoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002470"}
{"pmid": "21002471", "title": "[Heart ventricle, thrombus].", "content": "[Heart ventricle, thrombus].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002471"}
{"pmid": "21002472", "title": "MEDICAL school and commencement.", "content": "MEDICAL school and commencement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002472"}
{"pmid": "21002473", "title": "Intestinal obstruction.", "content": "Intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002473"}
{"pmid": "21002474", "title": "Practical suggestions for the care of obstetrical patients.", "content": "Practical suggestions for the care of obstetrical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002474"}
{"pmid": "21002475", "title": "A commentator's view of the medical dilemma.", "content": "A commentator's view of the medical dilemma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002475"}
{"pmid": "21002476", "title": "A comparative study of the metazoan parasites of man.", "content": "A comparative study of the metazoan parasites of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002476"}
{"pmid": "21002477", "title": "Some comments on the lipoprotein micelle theory of drug action.", "content": "Some comments on the lipoprotein micelle theory of drug action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002477"}
{"pmid": "21002479", "title": "Serum-protein level of Indian soldiers.", "content": "Serum-protein level of Indian soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002479"}
{"pmid": "21002478", "title": "Coronary disease; the Harveian oration of 1946.", "content": "Coronary disease; the Harveian oration of 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002478"}
{"pmid": "21002480", "title": "Leptospirosis canicola; a case treated with penicillin.", "content": "Leptospirosis canicola; a case treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002480"}
{"pmid": "21002481", "title": "Malignant granuloma of the nose.", "content": "Malignant granuloma of the nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002481"}
{"pmid": "21002482", "title": "Psychiatry at the Corps Exhaustion Centre; technique of rapid psychiatric assessment.", "content": "Psychiatry at the Corps Exhaustion Centre; technique of rapid psychiatric assessment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002482"}
{"pmid": "21002483", "title": "Malted foods for babies; trials with young rats.", "content": "Malted foods for babies; trials with young rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002483"}
{"pmid": "21002484", "title": "The spirit in which we work.", "content": "The spirit in which we work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002484"}
{"pmid": "21002485", "title": "Influenza B in 1945-46.", "content": "Influenza B in 1945-46.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002485"}
{"pmid": "21002486", "title": "Influenza B among West Indians; outbreaks in the Bahamas and in England.", "content": "Influenza B among West Indians; outbreaks in the Bahamas and in England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002486"}
{"pmid": "21002487", "title": "Icterus gravis neonatorum; end-results of treatment by blood-transfusion.", "content": "Icterus gravis neonatorum; end-results of treatment by blood-transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002487"}
{"pmid": "21002488", "title": "Detection of amino-acids in urine and other fluids.", "content": "Detection of amino-acids in urine and other fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002488"}
{"pmid": "21002490", "title": "Chilblains in servicewomen.", "content": "Chilblains in servicewomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002490"}
{"pmid": "21002489", "title": "Leucotomy technique.", "content": "Leucotomy technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002489"}
{"pmid": "21002491", "title": "Traumatic pulmonary oedema; treated with concentrated plasma.", "content": "Traumatic pulmonary oedema; treated with concentrated plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002491"}
{"pmid": "21002492", "title": "Acute phosgene poisoning; effects of plasma replacement.", "content": "Acute phosgene poisoning; effects of plasma replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002492"}
{"pmid": "21002493", "title": "Salt deficiency in sprue.", "content": "Salt deficiency in sprue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002493"}
{"pmid": "21002494", "title": "Myocardial fibrosis following arsenical therapy.", "content": "Myocardial fibrosis following arsenical therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002494"}
{"pmid": "21002495", "title": "Childlessness and the small family; a fertility survey in Luton.", "content": "Childlessness and the small family; a fertility survey in Luton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002495"}
{"pmid": "21002497", "title": "Surgery in peptic ulcer.", "content": "Surgery in peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002497"}
{"pmid": "21002498", "title": "Ophthalmic indications of systemic disease.", "content": "Ophthalmic indications of systemic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002498"}
{"pmid": "21002499", "title": "Plasma proteins.", "content": "Plasma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002499"}
{"pmid": "21002500", "title": "Medical Council in India.", "content": "Medical Council in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002500"}
{"pmid": "21002501", "title": "Diagnosis and treatment of eczema.", "content": "Diagnosis and treatment of eczema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002501"}
{"pmid": "21002502", "title": "Mepacrine intoxication and mental excitement and temporary insanity.", "content": "Mepacrine intoxication and mental excitement and temporary insanity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002502"}
{"pmid": "21002503", "title": "Transverse presentation.", "content": "Transverse presentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002503"}
{"pmid": "21002504", "title": "Costen's syndrome; a hitherto unrecognized cause of vague head pain.", "content": "Costen's syndrome; a hitherto unrecognized cause of vague head pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002504"}
{"pmid": "21002496", "title": "The treatment of syphilis; a survey.", "content": "The treatment of syphilis; a survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002496"}
{"pmid": "21002505", "title": "Generalized lymphatic carcinomatosis (cancerous lymphangitis) of the lungs, with special reference to miliary carcinomatosis and the syndrome of granulie froide.", "content": "Generalized lymphatic carcinomatosis (cancerous lymphangitis) of the lungs, with special reference to miliary carcinomatosis and the syndrome of granulie froide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002505"}
{"pmid": "21002507", "title": "Toxoplasmic encephalomyelitis, with the report of two cases.", "content": "Toxoplasmic encephalomyelitis, with the report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002507"}
{"pmid": "21002506", "title": "The Klinefelter-Reifenstein-Albright syndrome.", "content": "The Klinefelter-Reifenstein-Albright syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002506"}
{"pmid": "21002508", "title": "Nesidioblastoma; report of two cases responding to surgical removal.", "content": "Nesidioblastoma; report of two cases responding to surgical removal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002508"}
{"pmid": "21002509", "title": "Stricture of the oesophagus.", "content": "Stricture of the oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002509"}
{"pmid": "21002510", "title": "Juvenile rheumatism; a survey from the Children's Hospital, Melbourne, with an addendum on the follow-up system of the almoners of the hospital.", "content": "Juvenile rheumatism; a survey from the Children's Hospital, Melbourne, with an addendum on the follow-up system of the almoners of the hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002510"}
{"pmid": "21002511", "title": "Fibrositis and the common pains of daily practice.", "content": "Fibrositis and the common pains of daily practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002511"}
{"pmid": "21002512", "title": "Lumbago.", "content": "Lumbago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002512"}
{"pmid": "21002513", "title": "Spinal anaesthesia and the pregnant woman.", "content": "Spinal anaesthesia and the pregnant woman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002513"}
{"pmid": "21002514", "title": "A case of exomphalos successfully treated by early operation.", "content": "A case of exomphalos successfully treated by early operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002514"}
{"pmid": "21002515", "title": "Fibromyoma of the small intestine causing intussusception.", "content": "Fibromyoma of the small intestine causing intussusception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002515"}
{"pmid": "21002516", "title": "Some aspects of paramyotonia congenita.", "content": "Some aspects of paramyotonia congenita.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002516"}
{"pmid": "21002517", "title": "A diamond jubilee, 1886-1946; the Queensland Medical Society.", "content": "A diamond jubilee, 1886-1946; the Queensland Medical Society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002517"}
{"pmid": "21002518", "title": "The disorders of micturition.", "content": "The disorders of micturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002518"}
{"pmid": "21002519", "title": "Disorders of micturition in the female.", "content": "Disorders of micturition in the female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002519"}
{"pmid": "21002520", "title": "Toxic goitre in the middle-aged and elderly.", "content": "Toxic goitre in the middle-aged and elderly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002520"}
{"pmid": "21002521", "title": "The renal glomerular lesions in eclamptic toxaemia.", "content": "The renal glomerular lesions in eclamptic toxaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002521"}
{"pmid": "21002522", "title": "Repeated intraventricular injection of penicillin in severe intracranial infection; purulent meningitis and ventriculitis so treated, with clinical cure.", "content": "Repeated intraventricular injection of penicillin in severe intracranial infection; purulent meningitis and ventriculitis so treated, with clinical cure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002522"}
{"pmid": "21002523", "title": "Severe liver damage in infective hepatitis, with massive effusions and oedema; recovery.", "content": "Severe liver damage in infective hepatitis, with massive effusions and oedema; recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002523"}
{"pmid": "21002524", "title": "Disorders of micturition.", "content": "Disorders of micturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002524"}
{"pmid": "21002526", "title": "A case of tuberculous ulcer of the vulva.", "content": "A case of tuberculous ulcer of the vulva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002526"}
{"pmid": "21002525", "title": "The reaction of iodine with preparations of the thyreotrophic hormone.", "content": "The reaction of iodine with preparations of the thyreotrophic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002525"}
{"pmid": "21002527", "title": "Rickettsial diseases and their vectors with special reference to scrub typhus and trombidiosis.", "content": "Rickettsial diseases and their vectors with special reference to scrub typhus and trombidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002527"}
{"pmid": "21002528", "title": "The increase in white-aboriginal mixed bloods.", "content": "The increase in white-aboriginal mixed bloods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002528"}
{"pmid": "21002529", "title": "The zoological position of man and the data of physical anthropology.", "content": "The zoological position of man and the data of physical anthropology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002529"}
{"pmid": "21002531", "title": "Studies in the salmonellas.", "content": "Studies in the salmonellas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002531"}
{"pmid": "21002530", "title": "Ten years of diphtheria prophylaxis in the metropolitan area of South Australia.", "content": "Ten years of diphtheria prophylaxis in the metropolitan area of South Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002530"}
{"pmid": "21002532", "title": "Haemoglobinometry.", "content": "Haemoglobinometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002532"}
{"pmid": "21002533", "title": "The biochemistry of prothrombin.", "content": "The biochemistry of prothrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002533"}
{"pmid": "21002534", "title": "The care of the paralyses of poliomyelitis.", "content": "The care of the paralyses of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002534"}
{"pmid": "21002535", "title": "Special characteristics and requirements of orthopaedic surgery in industrial patients.", "content": "Special characteristics and requirements of orthopaedic surgery in industrial patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002535"}
{"pmid": "21002536", "title": "Sudeck's atrophy.", "content": "Sudeck's atrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002536"}
{"pmid": "21002537", "title": "Perthes's disease and its occurrence as a familial condition.", "content": "Perthes's disease and its occurrence as a familial condition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002537"}
{"pmid": "21002538", "title": "Hallux valgus and hallux rigidus.", "content": "Hallux valgus and hallux rigidus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002538"}
{"pmid": "21002539", "title": "Amputations.", "content": "Amputations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002539"}
{"pmid": "21002540", "title": "Lesions of the musculo-tendinous cuff of the shoulder.", "content": "Lesions of the musculo-tendinous cuff of the shoulder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002540"}
{"pmid": "21002541", "title": "Gramophone recordings of cardio-vascular and respiratory sounds.", "content": "Gramophone recordings of cardio-vascular and respiratory sounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002541"}
{"pmid": "21002542", "title": "Fracture-dislocation of the spine with locked articular processes.", "content": "Fracture-dislocation of the spine with locked articular processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002542"}
{"pmid": "21002543", "title": "A case of juvenile essential hypertension with encephalopathy.", "content": "A case of juvenile essential hypertension with encephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002543"}
{"pmid": "21002544", "title": "War surgery.", "content": "War surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002544"}
{"pmid": "21002545", "title": "Desert sores and cutaneous leishmaniasis.", "content": "Desert sores and cutaneous leishmaniasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002545"}
{"pmid": "21002546", "title": "War injuries in an evacuation hospital.", "content": "War injuries in an evacuation hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002546"}
{"pmid": "21002547", "title": "Neuropsychiatric aspects of war medicine.", "content": "Neuropsychiatric aspects of war medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002547"}
{"pmid": "21002548", "title": "Aviation medicine.", "content": "Aviation medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002548"}
{"pmid": "21002549", "title": "The problem of peptic ulcer in the military service.", "content": "The problem of peptic ulcer in the military service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002549"}
{"pmid": "21002550", "title": "Diverticulosis of the alimentary canal.", "content": "Diverticulosis of the alimentary canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002550"}
{"pmid": "21002551", "title": "The prevention of conduction deafness.", "content": "The prevention of conduction deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002551"}
{"pmid": "21002552", "title": "Schistosomiasis japonicum, a case report.", "content": "Schistosomiasis japonicum, a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002552"}
{"pmid": "21002553", "title": "Acute intestinal obstruction; a statement of fundamental principles.", "content": "Acute intestinal obstruction; a statement of fundamental principles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002553"}
{"pmid": "21002554", "title": "The acute abdomen in infancy and childhood; a case report of acute gonorrheal tubo-ovarian abscess in an infant of two months.", "content": "The acute abdomen in infancy and childhood; a case report of acute gonorrheal tubo-ovarian abscess in an infant of two months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002554"}
{"pmid": "21002555", "title": "Schistosomiasis japonica; diagnosis and treatment in American soldiers.", "content": "Schistosomiasis japonica; diagnosis and treatment in American soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002555"}
{"pmid": "21002556", "title": "Wartime activities of the Army Medical Department.", "content": "Wartime activities of the Army Medical Department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002556"}
{"pmid": "21002557", "title": "Scurvy; a survey of two hundred and forty-one cases.", "content": "Scurvy; a survey of two hundred and forty-one cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002557"}
{"pmid": "21002558", "title": "The tonic effects of insulin in acute alcoholism.", "content": "The tonic effects of insulin in acute alcoholism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002558"}
{"pmid": "21002559", "title": "Endometrosis of sigmoid, rectum, bladder and left ovary.", "content": "Endometrosis of sigmoid, rectum, bladder and left ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002559"}
{"pmid": "21002560", "title": "Benign gastric ulcer, with penetration into pancreas.", "content": "Benign gastric ulcer, with penetration into pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002560"}
{"pmid": "21002561", "title": "The effect of anticoagulants on the penicillin therapy and the pathologic lesion of subacute bacterial endocarditis.", "content": "The effect of anticoagulants on the penicillin therapy and the pathologic lesion of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002561"}
{"pmid": "21002562", "title": "Foreign bodies in the respiratory tract.", "content": "Foreign bodies in the respiratory tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002562"}
{"pmid": "21002563", "title": "Boston Medical Library; report of the President.", "content": "Boston Medical Library; report of the President.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002563"}
{"pmid": "21002564", "title": "Boston Medical Library; report of the Librarian.", "content": "Boston Medical Library; report of the Librarian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002564"}
{"pmid": "21002565", "title": "Diseases of the thyroid gland.", "content": "Diseases of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002565"}
{"pmid": "21002566", "title": "Dermoid cyst of left ovary, with twisted pedicle.", "content": "Dermoid cyst of left ovary, with twisted pedicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002566"}
{"pmid": "21002567", "title": "Syphilitic aortitis, with multiple fusiform and saccular aneurysms of thoracic aorta.", "content": "Syphilitic aortitis, with multiple fusiform and saccular aneurysms of thoracic aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002567"}
{"pmid": "21002568", "title": "The management of ambulatory peptic ulcer patients with protein hydrolysates.", "content": "The management of ambulatory peptic ulcer patients with protein hydrolysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002568"}
{"pmid": "21002569", "title": "Medical surveillance after malarial exposure.", "content": "Medical surveillance after malarial exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002569"}
{"pmid": "21002570", "title": "Surgical treatment of painful phantom limb; a preliminary report.", "content": "Surgical treatment of painful phantom limb; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002570"}
{"pmid": "21002571", "title": "The traumatic abdomen.", "content": "The traumatic abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002571"}
{"pmid": "21002572", "title": "Clinical experiences with chemical hazards in industry.", "content": "Clinical experiences with chemical hazards in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002572"}
{"pmid": "21002573", "title": "The evaluation of disabilities.", "content": "The evaluation of disabilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002573"}
{"pmid": "21002574", "title": "Diphtheria in upstate New York, 1908-1946.", "content": "Diphtheria in upstate New York, 1908-1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002574"}
{"pmid": "21002575", "title": "Reconditioning; the management of convalescence.", "content": "Reconditioning; the management of convalescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002575"}
{"pmid": "21002576", "title": "Veterans Medical Service Plan.", "content": "Veterans Medical Service Plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002576"}
{"pmid": "21002577", "title": "The isolation of Cl. tetani from infected talc.", "content": "The isolation of Cl. tetani from infected talc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002577"}
{"pmid": "21002578", "title": "Tetanus neonatorum; a report of three cases.", "content": "Tetanus neonatorum; a report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002578"}
{"pmid": "21002579", "title": "Tetanus; two cases treated with penicillin.", "content": "Tetanus; two cases treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002579"}
{"pmid": "21002580", "title": "Report on the incidence of rickets in New Zealand.", "content": "Report on the incidence of rickets in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002580"}
{"pmid": "21002581", "title": "Facial paresis of supranuclear type simulating that of peripheral origin.", "content": "Facial paresis of supranuclear type simulating that of peripheral origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002581"}
{"pmid": "21002583", "title": "Resuscitation by cardiac massage.", "content": "Resuscitation by cardiac massage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002583"}
{"pmid": "21002582", "title": "Arthritis in poliomyelitis; report of a case.", "content": "Arthritis in poliomyelitis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002582"}
{"pmid": "21002584", "title": "Lumbar paravertebral sympathetic block.", "content": "Lumbar paravertebral sympathetic block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002584"}
{"pmid": "21002585", "title": "The treatment of urethral stricture.", "content": "The treatment of urethral stricture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002585"}
{"pmid": "21002586", "title": "Thyroid deficiency following thyroidectomy.", "content": "Thyroid deficiency following thyroidectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002586"}
{"pmid": "21002587", "title": "Confluent smallpox; report of a case.", "content": "Confluent smallpox; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002587"}
{"pmid": "21002588", "title": "HEART disease and worker's compensation.", "content": "HEART disease and worker's compensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002588"}
{"pmid": "21002589", "title": "Post-partum necrosis of the anterior pituitary.", "content": "Post-partum necrosis of the anterior pituitary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002589"}
{"pmid": "21002590", "title": "Anterior mediastinal tumor with superior vena caval obstruction.", "content": "Anterior mediastinal tumor with superior vena caval obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002590"}
{"pmid": "21002591", "title": "Anaesthesia in intrathoracic surgery.", "content": "Anaesthesia in intrathoracic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002591"}
{"pmid": "21002592", "title": "Clinical features of the psychoneuroses in World War II veterans.", "content": "Clinical features of the psychoneuroses in World War II veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002592"}
{"pmid": "21002593", "title": "The use of intravenous iodine in preparing the patient with toxic diffuse goiter for operation.", "content": "The use of intravenous iodine in preparing the patient with toxic diffuse goiter for operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002593"}
{"pmid": "21002594", "title": "False-positive serologic tests for syphilis.", "content": "False-positive serologic tests for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002594"}
{"pmid": "21002595", "title": "Abdominal cesarean section in Asheville.", "content": "Abdominal cesarean section in Asheville.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002595"}
{"pmid": "21002596", "title": "Diagnosis and early management of inhaled and ingested foreign bodies.", "content": "Diagnosis and early management of inhaled and ingested foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002596"}
{"pmid": "21002597", "title": "Syncope as a diagnostic problem.", "content": "Syncope as a diagnostic problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002597"}
{"pmid": "21002598", "title": "The clinical importance of the Rh blood type.", "content": "The clinical importance of the Rh blood type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002598"}
{"pmid": "21002599", "title": "Spontaneous mediastinal emphysema; a case report.", "content": "Spontaneous mediastinal emphysema; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002599"}
{"pmid": "21002600", "title": "Agranulocytosis (hypogranulocytosis), of unknown cause.", "content": "Agranulocytosis (hypogranulocytosis), of unknown cause.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002600"}
{"pmid": "21002601", "title": "Disability evaluation.", "content": "Disability evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002601"}
{"pmid": "21002602", "title": "Chylous cyst of mesentery in a four year old.", "content": "Chylous cyst of mesentery in a four year old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002602"}
{"pmid": "21002604", "title": "Internal perforation of urachal abscess.", "content": "Internal perforation of urachal abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002604"}
{"pmid": "21002603", "title": "Differential diagnosis in right renal disease.", "content": "Differential diagnosis in right renal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002603"}
{"pmid": "21002605", "title": "Use of curare in abdominal surgery.", "content": "Use of curare in abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002605"}
{"pmid": "21002606", "title": "Cellophane wrapping and ligation of the patent ductus arteriosus.", "content": "Cellophane wrapping and ligation of the patent ductus arteriosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002606"}
{"pmid": "21002607", "title": "Early decortication in clotted hemothorax and empyema.", "content": "Early decortication in clotted hemothorax and empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002607"}
{"pmid": "21002608", "title": "Benadryl; b-dimethylaminoethyl benzhydryl ether hydrochloride.", "content": "Benadryl; b-dimethylaminoethyl benzhydryl ether hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002608"}
{"pmid": "21002609", "title": "Pulmonary tuberculosis and other thoracic diseases among Army separatees.", "content": "Pulmonary tuberculosis and other thoracic diseases among Army separatees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002609"}
{"pmid": "21002610", "title": "Delayed allergic reaction to penicillin in oil and wax treated with procaine intravenously.", "content": "Delayed allergic reaction to penicillin in oil and wax treated with procaine intravenously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002610"}
{"pmid": "21002611", "title": "Pneumonia.", "content": "Pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002611"}
{"pmid": "21002612", "title": "Influenza.", "content": "Influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002612"}
{"pmid": "21002614", "title": "Chilblains.", "content": "Chilblains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002614"}
{"pmid": "21002613", "title": "Sore throats and tonsilitis.", "content": "Sore throats and tonsilitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002613"}
{"pmid": "21002615", "title": "Winter ailments of the old.", "content": "Winter ailments of the old.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002615"}
{"pmid": "21002616", "title": "Winter ailments in infancy.", "content": "Winter ailments in infancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002616"}
{"pmid": "21002617", "title": "Low back pain and sciatica.", "content": "Low back pain and sciatica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002617"}
{"pmid": "21002618", "title": "Anaesthetics in obstetric practice.", "content": "Anaesthetics in obstetric practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002618"}
{"pmid": "21002619", "title": "Acne vulgaris and its treatment.", "content": "Acne vulgaris and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002619"}
{"pmid": "21002620", "title": "Geriatrics; a medical, social and economic problem.", "content": "Geriatrics; a medical, social and economic problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002620"}
{"pmid": "21002621", "title": "Vitamin K in general practice.", "content": "Vitamin K in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002621"}
{"pmid": "21002622", "title": "The early recognition of disease; malignant disease.", "content": "The early recognition of disease; malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002622"}
{"pmid": "21002623", "title": "The treatment of toxic goitre (thyrotoxicosis).", "content": "The treatment of toxic goitre (thyrotoxicosis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002623"}
{"pmid": "21002624", "title": "The Rh factor.", "content": "The Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002624"}
{"pmid": "21002626", "title": "TUBERCOLUSIS in Kashmir.", "content": "TUBERCOLUSIS in Kashmir.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002626"}
{"pmid": "21002625", "title": "Indications for electro-convulsive therapy.", "content": "Indications for electro-convulsive therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002625"}
{"pmid": "21002627", "title": "Venous surgery.", "content": "Venous surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002627"}
{"pmid": "21002628", "title": "The flowing characteristics of blood; hypothetical consequences of departures from the normal condition.", "content": "The flowing characteristics of blood; hypothetical consequences of departures from the normal condition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002628"}
{"pmid": "21002629", "title": "Radio-humeral synovitis.", "content": "Radio-humeral synovitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002629"}
{"pmid": "21002630", "title": "Allergy; its status and needs.", "content": "Allergy; its status and needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002630"}
{"pmid": "21002631", "title": "Pilonidal disease; a plea for simplification of its surgical management.", "content": "Pilonidal disease; a plea for simplification of its surgical management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002631"}
{"pmid": "21002632", "title": "Physical medicine in industrial injuries.", "content": "Physical medicine in industrial injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002632"}
{"pmid": "21002633", "title": "The administration of penicillin by the sublingual route.", "content": "The administration of penicillin by the sublingual route.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002633"}
{"pmid": "21002634", "title": "The effect of para-amino-salicylic acid in vitro and in vivo on virulent human type tubercle bacilli.", "content": "The effect of para-amino-salicylic acid in vitro and in vivo on virulent human type tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002634"}
{"pmid": "21002635", "title": "Saccular diverticula in the membranous labyrinth of mammalian embryos.", "content": "Saccular diverticula in the membranous labyrinth of mammalian embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002635"}
{"pmid": "21002636", "title": "Tobacco smoking and coronary artery disease; an analytical review of the literature.", "content": "Tobacco smoking and coronary artery disease; an analytical review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002636"}
{"pmid": "21002637", "title": "Orthopedics.", "content": "Orthopedics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002637"}
{"pmid": "21002639", "title": "Management of the convulsive child.", "content": "Management of the convulsive child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002639"}
{"pmid": "21002638", "title": "History of surgical anaesthesia; an exhibit commemorating the one hundredth anniversary of William Thomas Green Morton's first public demonstration of ether anaesthesia.", "content": "History of surgical anaesthesia; an exhibit commemorating the one hundredth anniversary of William Thomas Green Morton's first public demonstration of ether anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002638"}
{"pmid": "21002640", "title": "Neuro-psychiatric disorders, office and hospital treatment.", "content": "Neuro-psychiatric disorders, office and hospital treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002640"}
{"pmid": "21002641", "title": "Present problems and procedures in neuro-psychiatric out-patient service.", "content": "Present problems and procedures in neuro-psychiatric out-patient service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002641"}
{"pmid": "21002642", "title": "ORDINANCE to consolidate and amend the law relating to the establishment, control and maintenance of hospitals, to provide for the free treatment of patients, and to provide for matters incidental thereto.", "content": "ORDINANCE to consolidate and amend the law relating to the establishment, control and maintenance of hospitals, to provide for the free treatment of patients, and to provide for matters incidental thereto.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002642"}
{"pmid": "21002643", "title": "DRAFT ordinance to amend the law relating to hospitals in order to provide free hospital services and for matters incidental thereto.", "content": "DRAFT ordinance to amend the law relating to hospitals in order to provide free hospital services and for matters incidental thereto.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002643"}
{"pmid": "21002644", "title": "Public hospitals ordinance, 1946; an address to a combined meeting of the Northern and Southern Transvaal Branches of the Medical Association of South Africa on 10th July, 1946.", "content": "Public hospitals ordinance, 1946; an address to a combined meeting of the Northern and Southern Transvaal Branches of the Medical Association of South Africa on 10th July, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002644"}
{"pmid": "21002645", "title": "Family doctor and the state.", "content": "Family doctor and the state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002645"}
{"pmid": "21002646", "title": "Comments on the Transvaal Public Hospitals Ordinance, 1946.", "content": "Comments on the Transvaal Public Hospitals Ordinance, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002646"}
{"pmid": "21002647", "title": "Some aspects of amoebiasis in Africans.", "content": "Some aspects of amoebiasis in Africans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002647"}
{"pmid": "21002648", "title": "Prostatectomy in the 10th decade; report on two cases.", "content": "Prostatectomy in the 10th decade; report on two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002648"}
{"pmid": "21002649", "title": "South Africa's food requirements.", "content": "South Africa's food requirements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002649"}
{"pmid": "21002650", "title": "Some practical points in anaesthesia.", "content": "Some practical points in anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002650"}
{"pmid": "21002651", "title": "Age of the menarche on the Witwatersrand, South Africa.", "content": "Age of the menarche on the Witwatersrand, South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002651"}
{"pmid": "21002653", "title": "Surgery of the peripheral nerves.", "content": "Surgery of the peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002653"}
{"pmid": "21002654", "title": "After gastrectomy.", "content": "After gastrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002654"}
{"pmid": "21002652", "title": "The theory of intra-cellular energy production and its practical application in cardiovascular conditions.", "content": "The theory of intra-cellular energy production and its practical application in cardiovascular conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002652"}
{"pmid": "21002655", "title": "Rooiwater (bilharziasis).", "content": "Rooiwater (bilharziasis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002655"}
{"pmid": "21002656", "title": "CURE for relapsing malaria? lifting the curtain of secrecy.", "content": "CURE for relapsing malaria? lifting the curtain of secrecy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002656"}
{"pmid": "21002658", "title": "Cervical erosion.", "content": "Cervical erosion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002658"}
{"pmid": "21002657", "title": "Social medicine in the U. D. F.", "content": "Social medicine in the U. D. F.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002657"}
{"pmid": "21002659", "title": "The Manitoba Health Plan.", "content": "The Manitoba Health Plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002659"}
{"pmid": "21002660", "title": "A portable oxygen unit.", "content": "A portable oxygen unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002660"}
{"pmid": "21002661", "title": "Vaginal cell examination as a routine in diagnosis; a study of vaginal and cervical cytology as related to abnormal growths.", "content": "Vaginal cell examination as a routine in diagnosis; a study of vaginal and cervical cytology as related to abnormal growths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002661"}
{"pmid": "21002662", "title": "Histopathology of the common primary swellings of the peripheral lymph nodes.", "content": "Histopathology of the common primary swellings of the peripheral lymph nodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002662"}
{"pmid": "21002663", "title": "Primary tularemia pneumonia treated with streptomycin; report of two cases.", "content": "Primary tularemia pneumonia treated with streptomycin; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002663"}
{"pmid": "21002664", "title": "A pharmacological and radiological study of hemophilia.", "content": "A pharmacological and radiological study of hemophilia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002664"}
{"pmid": "21002665", "title": "Examination of the back; a diagnostic outline for standardized routine.", "content": "Examination of the back; a diagnostic outline for standardized routine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002665"}
{"pmid": "21002666", "title": "Amebiasis.", "content": "Amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002666"}
{"pmid": "21002667", "title": "Coexistent hookworm and tuberculosis.", "content": "Coexistent hookworm and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002667"}
{"pmid": "21002668", "title": "Chronic infestation with intestinal parasites in an engineer battalion with particular reference to Schistosoma japonicum.", "content": "Chronic infestation with intestinal parasites in an engineer battalion with particular reference to Schistosoma japonicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002668"}
{"pmid": "21002669", "title": "Infections of the neck following tooth extractions.", "content": "Infections of the neck following tooth extractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002669"}
{"pmid": "21002670", "title": "Thiouracil; clinical evaluation following two and one-half years' experience.", "content": "Thiouracil; clinical evaluation following two and one-half years' experience.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002670"}
{"pmid": "21002671", "title": "Diverticula of the digestive tract; a review of the literature with observations based on a survey of 1,000 consecutive office cases.", "content": "Diverticula of the digestive tract; a review of the literature with observations based on a survey of 1,000 consecutive office cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002671"}
{"pmid": "21002672", "title": "Appendicitis; a clinico-pathological study.", "content": "Appendicitis; a clinico-pathological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002672"}
{"pmid": "21002673", "title": "Hydrogen ion concentration of the senile vaginal mucosa before and after estrogenic therapy.", "content": "Hydrogen ion concentration of the senile vaginal mucosa before and after estrogenic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002673"}
{"pmid": "21002674", "title": "The incidence of pulmonary consolidations in the mild asthmatic.", "content": "The incidence of pulmonary consolidations in the mild asthmatic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002674"}
{"pmid": "21002675", "title": "Experiences with 412 successive abdominal wounds.", "content": "Experiences with 412 successive abdominal wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002675"}
{"pmid": "21002676", "title": "Diagnosis and treatment of office gynecological patients.", "content": "Diagnosis and treatment of office gynecological patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002676"}
{"pmid": "21002677", "title": "Gunshot wound of the sacrum with hypoproteinemia resulting from secondary hemorrhage and infection.", "content": "Gunshot wound of the sacrum with hypoproteinemia resulting from secondary hemorrhage and infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002677"}
{"pmid": "21002679", "title": "Essentials to adequate gynecologic patient study.", "content": "Essentials to adequate gynecologic patient study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002679"}
{"pmid": "21002678", "title": "Reducing the morbidity and mortality in surgery of the colon.", "content": "Reducing the morbidity and mortality in surgery of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002678"}
{"pmid": "21002680", "title": "The use of thiouracil in the treatment of thyrotoxicosis.", "content": "The use of thiouracil in the treatment of thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002680"}
{"pmid": "21002681", "title": "Acute cardiac emergencies.", "content": "Acute cardiac emergencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002681"}
{"pmid": "21002682", "title": "Acute rheumatic fever in young adults.", "content": "Acute rheumatic fever in young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002682"}
{"pmid": "21002683", "title": "Major surgery of the suppurative paranasal sinuses.", "content": "Major surgery of the suppurative paranasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002683"}
{"pmid": "21002684", "title": "Is overspecialization a threat?", "content": "Is overspecialization a threat?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002684"}
{"pmid": "21002685", "title": "Trends and progress in neuropsychiatry.", "content": "Trends and progress in neuropsychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002685"}
{"pmid": "21002686", "title": "Antibiotics.", "content": "Antibiotics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002686"}
{"pmid": "21002687", "title": "Erysipeloid.", "content": "Erysipeloid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002687"}
{"pmid": "21002688", "title": "Tests of biliary function.", "content": "Tests of biliary function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002688"}
{"pmid": "21002689", "title": "Nerve regeneration: observations on motor and sensory recovery in a case of injury to the radial nerve; summary of sensory phenomena observed between December 11, 1942 and December 11, 1943.", "content": "Nerve regeneration: observations on motor and sensory recovery in a case of injury to the radial nerve; summary of sensory phenomena observed between December 11, 1942 and December 11, 1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002689"}
{"pmid": "21002690", "title": "Congenital radio-ulnar synostosis.", "content": "Congenital radio-ulnar synostosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002690"}
{"pmid": "21002691", "title": "Loose bodies in the shoulder-joint.", "content": "Loose bodies in the shoulder-joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002691"}
{"pmid": "21002692", "title": "A case of lipodystrophia progressiva of the Laignel-Lavastine-Viard type.", "content": "A case of lipodystrophia progressiva of the Laignel-Lavastine-Viard type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002692"}
{"pmid": "21002693", "title": "Blood transfusion as a naval problem.", "content": "Blood transfusion as a naval problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002693"}
{"pmid": "21002694", "title": "Insulin therapy in acne vulgaris in tropics.", "content": "Insulin therapy in acne vulgaris in tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002694"}
{"pmid": "21002695", "title": "Racial and geographical variations in the frequencies of the blood groups.", "content": "Racial and geographical variations in the frequencies of the blood groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002695"}
{"pmid": "21002696", "title": "The leucocyte count in dengue.", "content": "The leucocyte count in dengue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002696"}
{"pmid": "21002697", "title": "Primary tuberculosis in young adults.", "content": "Primary tuberculosis in young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002697"}
{"pmid": "21002698", "title": "Cleido-cranial dysostosis.", "content": "Cleido-cranial dysostosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002698"}
{"pmid": "21002699", "title": "Sciatica.", "content": "Sciatica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002699"}
{"pmid": "21002700", "title": "The wartime log of a United States Navy hospital ship to 30 June 1943.", "content": "The wartime log of a United States Navy hospital ship to 30 June 1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002700"}
{"pmid": "21002701", "title": "The use of tantalum in tendon reconstruction of the hand.", "content": "The use of tantalum in tendon reconstruction of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002701"}
{"pmid": "21002702", "title": "Redundant duodenum; a radiographic study.", "content": "Redundant duodenum; a radiographic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002702"}
{"pmid": "21002703", "title": "Proctology in the U.S. Naval Hospital.", "content": "Proctology in the U.S. Naval Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002703"}
{"pmid": "21002704", "title": "Tsutsugamushi disease on Samar, Philippine Islands.", "content": "Tsutsugamushi disease on Samar, Philippine Islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002704"}
{"pmid": "21002705", "title": "Evaluation of therapeutic agents in plague; a review of the literature.", "content": "Evaluation of therapeutic agents in plague; a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002705"}
{"pmid": "21002706", "title": "Alcohol as a factor in naval delinquencies.", "content": "Alcohol as a factor in naval delinquencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002706"}
{"pmid": "21002707", "title": "A treatment for otitis externa in the tropics.", "content": "A treatment for otitis externa in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002707"}
{"pmid": "21002708", "title": "Colloid mucostatic impression technique for full lower dentures.", "content": "Colloid mucostatic impression technique for full lower dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002708"}
{"pmid": "21002709", "title": "Endogenous versus exogenous origin of reinfection type pulmonary tuberculosis; with case report.", "content": "Endogenous versus exogenous origin of reinfection type pulmonary tuberculosis; with case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002709"}
{"pmid": "21002710", "title": "Capillary fragility in rheumatic fever.", "content": "Capillary fragility in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002710"}
{"pmid": "21002711", "title": "Penicillin prophylaxis against acute otitis media in scarlet fever.", "content": "Penicillin prophylaxis against acute otitis media in scarlet fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002711"}
{"pmid": "21002712", "title": "The influence of combat on the incidence of intestinal parasites.", "content": "The influence of combat on the incidence of intestinal parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002712"}
{"pmid": "21002713", "title": "Penicillin in the treatment of louse-borne relapsing fever.", "content": "Penicillin in the treatment of louse-borne relapsing fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002713"}
{"pmid": "21002714", "title": "Diagnosis and surgical management of thoracoabdominal wounds aboard an assault transport.", "content": "Diagnosis and surgical management of thoracoabdominal wounds aboard an assault transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002714"}
{"pmid": "21002715", "title": "EARLIEST recorded instance of the use of biological warfare.", "content": "EARLIEST recorded instance of the use of biological warfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002715"}
{"pmid": "21002717", "title": "Healing of a fracture after delayed treatment.", "content": "Healing of a fracture after delayed treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002717"}
{"pmid": "21002716", "title": "Prosthetic restoration following shrapnel injury of mandible.", "content": "Prosthetic restoration following shrapnel injury of mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002716"}
{"pmid": "21002718", "title": "Leukemia aboard a destroyer.", "content": "Leukemia aboard a destroyer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002718"}
{"pmid": "21002719", "title": "A clinical note on the use of desoxycorticosterone acetate in the treatment of duodenal ulcer.", "content": "A clinical note on the use of desoxycorticosterone acetate in the treatment of duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002719"}
{"pmid": "21002721", "title": "Primary liposarcoma of bone; report of a case.", "content": "Primary liposarcoma of bone; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002721"}
{"pmid": "21002720", "title": "Treatment of uremia with continuous perutoneal irrigation.", "content": "Treatment of uremia with continuous perutoneal irrigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002720"}
{"pmid": "21002722", "title": "Gonorrheal endocarditis; report of a case.", "content": "Gonorrheal endocarditis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002722"}
{"pmid": "21002723", "title": "An apparatus for the reduction of fractures of the wrist and forearm.", "content": "An apparatus for the reduction of fractures of the wrist and forearm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002723"}
{"pmid": "21002724", "title": "Toxic effects of arsenical compounds, as administered in the United States Navy in 1945, with special reference to arsenical dermatitis.", "content": "Toxic effects of arsenical compounds, as administered in the United States Navy in 1945, with special reference to arsenical dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002724"}
{"pmid": "21002725", "title": "The curve of absolute photopic sensitivity of the eye in the region from 300 to 950 m-mu.", "content": "The curve of absolute photopic sensitivity of the eye in the region from 300 to 950 m-mu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002725"}
{"pmid": "21002726", "title": "Explanation of neural crests in Amphibia.", "content": "Explanation of neural crests in Amphibia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002726"}
{"pmid": "21002727", "title": "On the rearrangement of nematodes of the order Ascaridata Skrjabin, 1915.", "content": "On the rearrangement of nematodes of the order Ascaridata Skrjabin, 1915.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002727"}
{"pmid": "21002728", "title": "The influence of mechanical treatment of milk and cream on the size distribution of the fat globules.", "content": "The influence of mechanical treatment of milk and cream on the size distribution of the fat globules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002728"}
{"pmid": "21002729", "title": "The feeding value of seaweeds.", "content": "The feeding value of seaweeds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002729"}
{"pmid": "21002730", "title": "Insecticidal properties of the indigobush (Amorpha fruticosa).", "content": "Insecticidal properties of the indigobush (Amorpha fruticosa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002730"}
{"pmid": "21002731", "title": "Environmental modification of fiber properties as a source of error in cotton experiments.", "content": "Environmental modification of fiber properties as a source of error in cotton experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002731"}
{"pmid": "21002732", "title": "The moon and plant growth.", "content": "The moon and plant growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002732"}
{"pmid": "21002733", "title": "The course of the controversy on freedom in science.", "content": "The course of the controversy on freedom in science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002733"}
{"pmid": "21002734", "title": "Occurrence of foot louse of sheep in the British Isles.", "content": "Occurrence of foot louse of sheep in the British Isles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002734"}
{"pmid": "21002735", "title": "Glycogen phosphorylysis in alloxan-diabetic rats.", "content": "Glycogen phosphorylysis in alloxan-diabetic rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002735"}
{"pmid": "21002736", "title": "Alloxan diabetes and kidney function.", "content": "Alloxan diabetes and kidney function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002736"}
{"pmid": "21002737", "title": "The thyroid and tuberculosis.", "content": "The thyroid and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002737"}
{"pmid": "21002738", "title": "Infra-red recording with the cathode ray oscilloscope.", "content": "Infra-red recording with the cathode ray oscilloscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002738"}
{"pmid": "21002739", "title": "Bond-energies and isomerization.", "content": "Bond-energies and isomerization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002739"}
{"pmid": "21002740", "title": "Carbon sources in the photosynthesis of aquatic plants.", "content": "Carbon sources in the photosynthesis of aquatic plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002740"}
{"pmid": "21002741", "title": "Devastation.", "content": "Devastation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002741"}
{"pmid": "21002742", "title": "The rumen process as a functional field; an attempt at synthesis.", "content": "The rumen process as a functional field; an attempt at synthesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002742"}
{"pmid": "21002743", "title": "Public health in Great Britain during the war.", "content": "Public health in Great Britain during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002743"}
{"pmid": "21002745", "title": "Use of water purified by synthetic resin ion-exchange methods for the study of mineral deficiencies in plants.", "content": "Use of water purified by synthetic resin ion-exchange methods for the study of mineral deficiencies in plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002745"}
{"pmid": "21002744", "title": "Activity of vitamin A-acid in the rat.", "content": "Activity of vitamin A-acid in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002744"}
{"pmid": "21002746", "title": "Adenosine triphosphate in mammalian spermatozoa.", "content": "Adenosine triphosphate in mammalian spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002746"}
{"pmid": "21002747", "title": "Inhibiting action of fluorophosphonates on cholinesterase.", "content": "Inhibiting action of fluorophosphonates on cholinesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002747"}
{"pmid": "21002748", "title": "Mitotic disturbances induced in yeast by chemicals, and their significance for the interpretation of the normal chromosome conditions of yeast.", "content": "Mitotic disturbances induced in yeast by chemicals, and their significance for the interpretation of the normal chromosome conditions of yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002748"}
{"pmid": "21002749", "title": "Reticulocytosis following the administration of thymine to splenectomized rabbits.", "content": "Reticulocytosis following the administration of thymine to splenectomized rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002749"}
{"pmid": "21002750", "title": "Segmentation of the spinal cord in the human embryo.", "content": "Segmentation of the spinal cord in the human embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002750"}
{"pmid": "21002751", "title": "Blood groups of Burmese.", "content": "Blood groups of Burmese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002751"}
{"pmid": "21002752", "title": "Rheological properties of high-viscosity solutions of lung molecules.", "content": "Rheological properties of high-viscosity solutions of lung molecules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002752"}
{"pmid": "21002753", "title": "Application of gammexane to arthropods of veterinary importance.", "content": "Application of gammexane to arthropods of veterinary importance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002753"}
{"pmid": "21002755", "title": "Ergosterol from the mycelium of Penicillium notatum (submerged culture).", "content": "Ergosterol from the mycelium of Penicillium notatum (submerged culture).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002755"}
{"pmid": "21002756", "title": "The effect on the chick embryo of the simultaneous inoculation of stool, streptomycin, and penicillin.", "content": "The effect on the chick embryo of the simultaneous inoculation of stool, streptomycin, and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002756"}
{"pmid": "21002757", "title": "Prothrombin and fibrinolysin.", "content": "Prothrombin and fibrinolysin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002757"}
{"pmid": "21002758", "title": "Minimal electroencephalographic response to metrazol as a method for measuring the convulsive threshold for use in human beings.", "content": "Minimal electroencephalographic response to metrazol as a method for measuring the convulsive threshold for use in human beings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002758"}
{"pmid": "21002759", "title": "Utility of sulfa drugs for the inhibition of mold respiration in grain.", "content": "Utility of sulfa drugs for the inhibition of mold respiration in grain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002759"}
{"pmid": "21002761", "title": "The science training group in the Washington area.", "content": "The science training group in the Washington area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002761"}
{"pmid": "21002764", "title": "A color reaction given by streptomycin.", "content": "A color reaction given by streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002764"}
{"pmid": "21002767", "title": "Method for making filters transmitting the near ultraviolet and absorbing visual light.", "content": "Method for making filters transmitting the near ultraviolet and absorbing visual light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002767"}
{"pmid": "21002765", "title": "Relation of vapor-pressure deficit to evaporation from a spherical atmometer in an air-conditioned room.", "content": "Relation of vapor-pressure deficit to evaporation from a spherical atmometer in an air-conditioned room.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002765"}
{"pmid": "21002768", "title": "Some notes on the cancer problem.", "content": "Some notes on the cancer problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002768"}
{"pmid": "21002770", "title": "The future of diagnostic testing in clinical psychology.", "content": "The future of diagnostic testing in clinical psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002770"}
{"pmid": "21002771", "title": "The personal inventory; its derivation and validation.", "content": "The personal inventory; its derivation and validation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002771"}
{"pmid": "21002772", "title": "A clinical approach to reporting psychological test data.", "content": "A clinical approach to reporting psychological test data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002772"}
{"pmid": "21002773", "title": "Auroratone films for the treatment of psychotic depressions in an Army general hospital.", "content": "Auroratone films for the treatment of psychotic depressions in an Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002773"}
{"pmid": "21002774", "title": "A practical program of inservice training for military clinical psychologists.", "content": "A practical program of inservice training for military clinical psychologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002774"}
{"pmid": "21002775", "title": "The Wechsler-Bellevue scale as an aid in psychiatric diagnosis.", "content": "The Wechsler-Bellevue scale as an aid in psychiatric diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002775"}
{"pmid": "21002776", "title": "Detection of anxiety by use of the Wechsler scale.", "content": "Detection of anxiety by use of the Wechsler scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002776"}
{"pmid": "21002777", "title": "The use of personal experience in thematic apperception test story plots.", "content": "The use of personal experience in thematic apperception test story plots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002777"}
{"pmid": "21002778", "title": "Non-structured approach to the study of children's fears.", "content": "Non-structured approach to the study of children's fears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002778"}
{"pmid": "21002779", "title": "Are nondirective techniques sometimes too directive?", "content": "Are nondirective techniques sometimes too directive?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002779"}
{"pmid": "21002780", "title": "Directive psychotherapy; personality integration and self-regulation.", "content": "Directive psychotherapy; personality integration and self-regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002780"}
{"pmid": "21002781", "title": "Situational impotence.", "content": "Situational impotence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002781"}
{"pmid": "21002782", "title": "The hypno-analytic location of a lost object.", "content": "The hypno-analytic location of a lost object.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002782"}
{"pmid": "21002783", "title": "The American Association on Mental Deficiency; brief history and purposes.", "content": "The American Association on Mental Deficiency; brief history and purposes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002783"}
{"pmid": "21002784", "title": "Observations on the early differentiation of the motor neuroblasts in the spinal cord of the chick.", "content": "Observations on the early differentiation of the motor neuroblasts in the spinal cord of the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002784"}
{"pmid": "21002785", "title": "An aberrant trigemino-cerebellar tract in the human brain.", "content": "An aberrant trigemino-cerebellar tract in the human brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002785"}
{"pmid": "21002786", "title": "Afferent nerve endings in the ganglia of the intermuscular plexus of the dog's oesophagus.", "content": "Afferent nerve endings in the ganglia of the intermuscular plexus of the dog's oesophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002786"}
{"pmid": "21002787", "title": "Metrical and non-metrical features of the muscular branches of the median nerve.", "content": "Metrical and non-metrical features of the muscular branches of the median nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002787"}
{"pmid": "21002788", "title": "Metrical and non-metrical features of the muscular branches of the sciatic nerve and its medial and lateral popliteal divisions.", "content": "Metrical and non-metrical features of the muscular branches of the sciatic nerve and its medial and lateral popliteal divisions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002788"}
{"pmid": "21002789", "title": "The cytoarchitecture of the cerebral cortex of Ateles; a critical examination of architectonic studies.", "content": "The cytoarchitecture of the cerebral cortex of Ateles; a critical examination of architectonic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002789"}
{"pmid": "21002790", "title": "Analysis of one hundred cases of epilepsy.", "content": "Analysis of one hundred cases of epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002790"}
{"pmid": "21002791", "title": "Ataxia of the legs and loss of vibration; an isolated spinal syndrome.", "content": "Ataxia of the legs and loss of vibration; an isolated spinal syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002791"}
{"pmid": "21002792", "title": "The relationship of the vegetative nervous system to anginal anxiety.", "content": "The relationship of the vegetative nervous system to anginal anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002792"}
{"pmid": "21002793", "title": "Results of repetition of electroencephalography in adult epileptics.", "content": "Results of repetition of electroencephalography in adult epileptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002793"}
{"pmid": "21002794", "title": "The emotionally unfit soldier; psychiatric study of 12,000 soldiers in an infantry Replacement Training Center.", "content": "The emotionally unfit soldier; psychiatric study of 12,000 soldiers in an infantry Replacement Training Center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002794"}
{"pmid": "21002795", "title": "Sketches of neuropsychiatry in war and peace.", "content": "Sketches of neuropsychiatry in war and peace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002795"}
{"pmid": "21002796", "title": "The significance of non-conforming behavior in the military service.", "content": "The significance of non-conforming behavior in the military service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002796"}
{"pmid": "21002797", "title": "PERSONALITY diseases.", "content": "PERSONALITY diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002797"}
{"pmid": "21002798", "title": "SIMPLICITY versus complexity in combating fears; an interview in a group psychotherapy class with private patients.", "content": "SIMPLICITY versus complexity in combating fears; an interview in a group psychotherapy class with private patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002798"}
{"pmid": "21002799", "title": "SENTIMENTALISM OF exceptionality and realism of averageness; physician's comment on a panel discussion.", "content": "SENTIMENTALISM OF exceptionality and realism of averageness; physician's comment on a panel discussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002799"}
{"pmid": "21002800", "title": "Continuous caudal analgesia requires expert nursing care.", "content": "Continuous caudal analgesia requires expert nursing care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002800"}
{"pmid": "21002801", "title": "New ways in personnel administration.", "content": "New ways in personnel administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002801"}
{"pmid": "21002802", "title": "A social and economic poll of nurses.", "content": "A social and economic poll of nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002802"}
{"pmid": "21002803", "title": "Artificial aids to hearing.", "content": "Artificial aids to hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002803"}
{"pmid": "21002804", "title": "The care and education of the tuberculous patient.", "content": "The care and education of the tuberculous patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002804"}
{"pmid": "21002805", "title": "Self-demand feeding for babies.", "content": "Self-demand feeding for babies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002805"}
{"pmid": "21002806", "title": "Nursing care in hyperthyroidism.", "content": "Nursing care in hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002806"}
{"pmid": "21002807", "title": "TUBERCULOSIS case-finding programs in schools of nursing.", "content": "TUBERCULOSIS case-finding programs in schools of nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002807"}
{"pmid": "21002808", "title": "Changing attitudes in scarlet fever control.", "content": "Changing attitudes in scarlet fever control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002808"}
{"pmid": "21002809", "title": "Personnel practices in the nursing profession.", "content": "Personnel practices in the nursing profession.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002809"}
{"pmid": "21002810", "title": "Some complications in obstetrics.", "content": "Some complications in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002810"}
{"pmid": "21002811", "title": "The flying squad, an emergency obstetrical service in Oxfordshire.", "content": "The flying squad, an emergency obstetrical service in Oxfordshire.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002811"}
{"pmid": "21002813", "title": "The anaemias, a study of age incidence.", "content": "The anaemias, a study of age incidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002813"}
{"pmid": "21002812", "title": "Atomic energy and its application in medicine.", "content": "Atomic energy and its application in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002812"}
{"pmid": "21002814", "title": "Nursing problems in the rehabilitation of spinal cord injuries.", "content": "Nursing problems in the rehabilitation of spinal cord injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002814"}
{"pmid": "21002815", "title": "Selection tests given to nursing applicants.", "content": "Selection tests given to nursing applicants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002815"}
{"pmid": "21002816", "title": "Recent advances in disease of the new born.", "content": "Recent advances in disease of the new born.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002816"}
{"pmid": "21002817", "title": "The health visitor and the after-care of tuberculosis patients.", "content": "The health visitor and the after-care of tuberculosis patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002817"}
{"pmid": "21002818", "title": "Cardiac catheterisation.", "content": "Cardiac catheterisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002818"}
{"pmid": "21002819", "title": "Nursing care during penicillin inhalation therapy.", "content": "Nursing care during penicillin inhalation therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002819"}
{"pmid": "21002820", "title": "The use of health records in industry.", "content": "The use of health records in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002820"}
{"pmid": "21002821", "title": "Oxygen therapy.", "content": "Oxygen therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002821"}
{"pmid": "21002822", "title": "Skin grafts in war and peace.", "content": "Skin grafts in war and peace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002822"}
{"pmid": "21002823", "title": "Notes on the organization of student nurses' theoretical and practical training.", "content": "Notes on the organization of student nurses' theoretical and practical training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002823"}
{"pmid": "21002824", "title": "Education in the United States and Canada.", "content": "Education in the United States and Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002824"}
{"pmid": "21002826", "title": "The principles of teaching; the teacher's art.", "content": "The principles of teaching; the teacher's art.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002826"}
{"pmid": "21002825", "title": "The care of wounds in the ward and the problem of hospital infection.", "content": "The care of wounds in the ward and the problem of hospital infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002825"}
{"pmid": "21002827", "title": "The war record of a Victorian woman.", "content": "The war record of a Victorian woman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002827"}
{"pmid": "21002828", "title": "Visual standards and job requirements.", "content": "Visual standards and job requirements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002828"}
{"pmid": "21002829", "title": "Visual training.", "content": "Visual training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002829"}
{"pmid": "21002830", "title": "Comments on orthoptics.", "content": "Comments on orthoptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002830"}
{"pmid": "21002832", "title": "A multi-step sector photometer.", "content": "A multi-step sector photometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002832"}
{"pmid": "21002834", "title": "Radioactive light sources.", "content": "Radioactive light sources.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002834"}
{"pmid": "21002833", "title": "Plastic filters for the visible and near infra-red regions.", "content": "Plastic filters for the visible and near infra-red regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002833"}
{"pmid": "21002835", "title": "Color vision and color blindness; a mechanism in terms of modern evidence.", "content": "Color vision and color blindness; a mechanism in terms of modern evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002835"}
{"pmid": "21002836", "title": "A screening test for defective red-green vision.", "content": "A screening test for defective red-green vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002836"}
{"pmid": "21002838", "title": "Trifocals; a brief for universal acceptance.", "content": "Trifocals; a brief for universal acceptance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002838"}
{"pmid": "21002837", "title": "A simple cell for spectroscopic examination of volatile liquids.", "content": "A simple cell for spectroscopic examination of volatile liquids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002837"}
{"pmid": "21002839", "title": "The technique of fitting scleraform contact lenses; the mechanical optical and physical characteristics of an ideal contact lens.", "content": "The technique of fitting scleraform contact lenses; the mechanical optical and physical characteristics of an ideal contact lens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002839"}
{"pmid": "21002840", "title": "Development of the auditory ossicles.", "content": "Development of the auditory ossicles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002840"}
{"pmid": "21002841", "title": "Studies on the inheritance of deafness in the pupils of the Clarke School for the Deaf.", "content": "Studies on the inheritance of deafness in the pupils of the Clarke School for the Deaf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002841"}
{"pmid": "21002842", "title": "Studies on the inheritance of deafness in the pupils of the Clarke School for the Deaf; genetic analysis of data and pedigrees.", "content": "Studies on the inheritance of deafness in the pupils of the Clarke School for the Deaf; genetic analysis of data and pedigrees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002842"}
{"pmid": "21002843", "title": "The use of x-ray in chronic mastoid condition.", "content": "The use of x-ray in chronic mastoid condition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002843"}
{"pmid": "21002844", "title": "The use of x-ray in chronic mastoid condition; x-ray aspects.", "content": "The use of x-ray in chronic mastoid condition; x-ray aspects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002844"}
{"pmid": "21002845", "title": "Hemostasis after adenoid operations.", "content": "Hemostasis after adenoid operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002845"}
{"pmid": "21002846", "title": "Necropsies on Okinawans; anatomic and pathologic observations.", "content": "Necropsies on Okinawans; anatomic and pathologic observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002846"}
{"pmid": "21002847", "title": "Bilateral ovarian aplasia.", "content": "Bilateral ovarian aplasia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002847"}
{"pmid": "21002848", "title": "Eclampsia; report of a case in which there was extensive destruction of the brain.", "content": "Eclampsia; report of a case in which there was extensive destruction of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002848"}
{"pmid": "21002849", "title": "Temporal arteritis; report of a case and a comparison with respect to periarteritis nodosa.", "content": "Temporal arteritis; report of a case and a comparison with respect to periarteritis nodosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002849"}
{"pmid": "21002850", "title": "Lesions of reticuloendothelial cells in anaphylactic shock.", "content": "Lesions of reticuloendothelial cells in anaphylactic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002850"}
{"pmid": "21002851", "title": "Carotid-cavernous fistula.", "content": "Carotid-cavernous fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002851"}
{"pmid": "21002852", "title": "Truncus arteriosus communis persistens.", "content": "Truncus arteriosus communis persistens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002852"}
{"pmid": "21002853", "title": "Atherosclerosis and arteriosclerosis in dogs following ingestion of cholesterol and thiouracil.", "content": "Atherosclerosis and arteriosclerosis in dogs following ingestion of cholesterol and thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002853"}
{"pmid": "21002854", "title": "Further evidence for successive stages in the formation of neoplasms.", "content": "Further evidence for successive stages in the formation of neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002854"}
{"pmid": "21002859", "title": "Infantile cortical hyperostoses.", "content": "Infantile cortical hyperostoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002859"}
{"pmid": "21002860", "title": "The use of penicillin in the treatment of subacute bacterial endocarditis in children.", "content": "The use of penicillin in the treatment of subacute bacterial endocarditis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002860"}
{"pmid": "21002861", "title": "Penicillin in the treatment of the syphilitic infant; a progress report.", "content": "Penicillin in the treatment of the syphilitic infant; a progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002861"}
{"pmid": "21002862", "title": "Methemoglobinemia; two cases in newborn infants caused by nitrates in well water.", "content": "Methemoglobinemia; two cases in newborn infants caused by nitrates in well water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002862"}
{"pmid": "21002863", "title": "Methemoglobinemia occurring in infants fed milk diluted with well water of high nitrate content.", "content": "Methemoglobinemia occurring in infants fed milk diluted with well water of high nitrate content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002863"}
{"pmid": "21002864", "title": "The diagnosis of abortive poliomyelitis; a study of illnesses occurring in 1,123 contacts of patients with poliomyelitis.", "content": "The diagnosis of abortive poliomyelitis; a study of illnesses occurring in 1,123 contacts of patients with poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002864"}
{"pmid": "21002865", "title": "The effects of active immunization of the mother upon the offspring.", "content": "The effects of active immunization of the mother upon the offspring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002865"}
{"pmid": "21002866", "title": "An epidemic of diarrhea in the newborn nursery caused by a milk-borne epidemic in the community.", "content": "An epidemic of diarrhea in the newborn nursery caused by a milk-borne epidemic in the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002866"}
{"pmid": "21002867", "title": "The effect of salicylate administration on the prothrombin time.", "content": "The effect of salicylate administration on the prothrombin time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002867"}
{"pmid": "21002868", "title": "Acid-enzyme converted corn syrup in infant feeding.", "content": "Acid-enzyme converted corn syrup in infant feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002868"}
{"pmid": "21002869", "title": "Squint in children.", "content": "Squint in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002869"}
{"pmid": "21002870", "title": "Heart disease in children in a rural Iowa County; particularly in relation to rheumatic fever.", "content": "Heart disease in children in a rural Iowa County; particularly in relation to rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002870"}
{"pmid": "21002871", "title": "The pediatric intern.", "content": "The pediatric intern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002871"}
{"pmid": "21002872", "title": "The Permanente Health Plan.", "content": "The Permanente Health Plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002872"}
{"pmid": "21002873", "title": "Atomic energy.", "content": "Atomic energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002873"}
{"pmid": "21002874", "title": "Mandrake.", "content": "Mandrake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002874"}
{"pmid": "21002875", "title": "Pharmaceutical education in Poland.", "content": "Pharmaceutical education in Poland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002875"}
{"pmid": "21002876", "title": "The quantitative assay of specific alkaloid constituents of some vegetable drugs.", "content": "The quantitative assay of specific alkaloid constituents of some vegetable drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002876"}
{"pmid": "21002877", "title": "The investigation of some Western Australian plants of possible medicinal value.", "content": "The investigation of some Western Australian plants of possible medicinal value.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002877"}
{"pmid": "21002878", "title": "Bases for skin therapy, 1946.", "content": "Bases for skin therapy, 1946.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002878"}
{"pmid": "21002879", "title": "Organic arsenical drugs.", "content": "Organic arsenical drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002879"}
{"pmid": "21002880", "title": "Observations on pharmaceutical hypochlorite solutions.", "content": "Observations on pharmaceutical hypochlorite solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002880"}
{"pmid": "21002881", "title": "Australian shark liver oil.", "content": "Australian shark liver oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002881"}
{"pmid": "21002882", "title": "The teaching pharmacy.", "content": "The teaching pharmacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002882"}
{"pmid": "21002883", "title": "The work of Pharmaceutical Defence Limited.", "content": "The work of Pharmaceutical Defence Limited.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002883"}
{"pmid": "21002884", "title": "Pharmaceutical education in Canada.", "content": "Pharmaceutical education in Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002884"}
{"pmid": "21002885", "title": "Care in the use and storage of drugs and poisons in the home.", "content": "Care in the use and storage of drugs and poisons in the home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002885"}
{"pmid": "21002886", "title": "The post-war pharmacy.", "content": "The post-war pharmacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002886"}
{"pmid": "21002887", "title": "PHARMACY in occupied Europe.", "content": "PHARMACY in occupied Europe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002887"}
{"pmid": "21002888", "title": "Shakespeare's herbs; British simples for British bodies.", "content": "Shakespeare's herbs; British simples for British bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002888"}
{"pmid": "21002892", "title": "Actions of cyanate.", "content": "Actions of cyanate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002892"}
{"pmid": "21002894", "title": "Method for the estimation of barbituric and thiobarbituric acids in biological materials.", "content": "Method for the estimation of barbituric and thiobarbituric acids in biological materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002894"}
{"pmid": "21002895", "title": "Kemithal; a new intravenous anaesthetic.", "content": "Kemithal; a new intravenous anaesthetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002895"}
{"pmid": "21002896", "title": "Folic acid, a new anti-anaemia factor.", "content": "Folic acid, a new anti-anaemia factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002896"}
{"pmid": "21002897", "title": "Up-to-date on vitamin C.", "content": "Up-to-date on vitamin C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002897"}
{"pmid": "21002898", "title": "Pharmacological and toxicological studies on salicylamide.", "content": "Pharmacological and toxicological studies on salicylamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002898"}
{"pmid": "21002900", "title": "The influence of physiologically active compounds and their inactive homologs on phase boundary potentials.", "content": "The influence of physiologically active compounds and their inactive homologs on phase boundary potentials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002900"}
{"pmid": "21002899", "title": "The anesthetic effects and toxicities of some new barbituric acid derivatives administered to mice and rats.", "content": "The anesthetic effects and toxicities of some new barbituric acid derivatives administered to mice and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002899"}
{"pmid": "21002901", "title": "A study of the microbiological assay of riboflavin.", "content": "A study of the microbiological assay of riboflavin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002901"}
{"pmid": "21002902", "title": "The evaluation of antipyretics against pyrogen-induced fever.", "content": "The evaluation of antipyretics against pyrogen-induced fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002902"}
{"pmid": "21002903", "title": "Digitalis; the collaborative study of the assay of digitalis and its preparations by the chemical and cat methods.", "content": "Digitalis; the collaborative study of the assay of digitalis and its preparations by the chemical and cat methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002903"}
{"pmid": "21002904", "title": "Pentobarbital sodium anesthesia in the Syrian hamster.", "content": "Pentobarbital sodium anesthesia in the Syrian hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002904"}
{"pmid": "21002905", "title": "Dihydroxypropyl theophylline; its preparation and pharmacological and clinical study.", "content": "Dihydroxypropyl theophylline; its preparation and pharmacological and clinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002905"}
{"pmid": "21002906", "title": "A chemical investigation of Celastrus paniculata Willd.", "content": "A chemical investigation of Celastrus paniculata Willd.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002906"}
{"pmid": "21002907", "title": "A chemical investigation of Sphaeranthus indicus Linn.", "content": "A chemical investigation of Sphaeranthus indicus Linn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002907"}
{"pmid": "21002908", "title": "Hydrophilic acid ointments for the debridement of burns.", "content": "Hydrophilic acid ointments for the debridement of burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002908"}
{"pmid": "21002909", "title": "The gastrointestinal absorption and destruction of penicillin.", "content": "The gastrointestinal absorption and destruction of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002909"}
{"pmid": "21002910", "title": "Apparatus, for tablet disintegration, and for shaking-out extractions.", "content": "Apparatus, for tablet disintegration, and for shaking-out extractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002910"}
{"pmid": "21002911", "title": "A survey of the present status of red squill as a rodenticide.", "content": "A survey of the present status of red squill as a rodenticide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002911"}
{"pmid": "21002912", "title": "The toxicity of sodium 3,12-dihydroxy-7-cholanate and its influence on bile flow in rats.", "content": "The toxicity of sodium 3,12-dihydroxy-7-cholanate and its influence on bile flow in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002912"}
{"pmid": "21002913", "title": "A study to determine the toxicity of fumaric acid.", "content": "A study to determine the toxicity of fumaric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002913"}
{"pmid": "21002914", "title": "The stability of solutions of urea peroxide in glycerol, isopropanol, and ethylene glycol.", "content": "The stability of solutions of urea peroxide in glycerol, isopropanol, and ethylene glycol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002914"}
{"pmid": "21002915", "title": "Amino alcohols; arylethanolamines.", "content": "Amino alcohols; arylethanolamines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002915"}
{"pmid": "21002916", "title": "Pyrethrum culture investigations in Nebraska.", "content": "Pyrethrum culture investigations in Nebraska.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002916"}
{"pmid": "21002917", "title": "An assay for choline chloride in pharmaceutical products.", "content": "An assay for choline chloride in pharmaceutical products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002917"}
{"pmid": "21002918", "title": "The extraction of caffeine from pharmaceutical preparations.", "content": "The extraction of caffeine from pharmaceutical preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002918"}
{"pmid": "21002919", "title": "The identification of an acid in the root bark of Viburnum prunifolium.", "content": "The identification of an acid in the root bark of Viburnum prunifolium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002919"}
{"pmid": "21002921", "title": "A new surgical suture.", "content": "A new surgical suture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002921"}
{"pmid": "21002920", "title": "The effect of agar upon the germicidal efficiency of the quaternary ammonium salts.", "content": "The effect of agar upon the germicidal efficiency of the quaternary ammonium salts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002920"}
{"pmid": "21002922", "title": "A critical survey of the antacids.", "content": "A critical survey of the antacids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002922"}
{"pmid": "21002923", "title": "Stability of penicillin cream B. P. and sterilised penicillin cream B. P.", "content": "Stability of penicillin cream B. P. and sterilised penicillin cream B. P.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002923"}
{"pmid": "21002924", "title": "Protein hydrolysates.", "content": "Protein hydrolysates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002924"}
{"pmid": "21002925", "title": "STREPTOMYCIN production.", "content": "STREPTOMYCIN production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002925"}
{"pmid": "21002926", "title": "Coughs and cough mixtures.", "content": "Coughs and cough mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002926"}
{"pmid": "21002927", "title": "The therapy of the menopause.", "content": "The therapy of the menopause.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002927"}
{"pmid": "21002928", "title": "Atropine and lachesine.", "content": "Atropine and lachesine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002928"}
{"pmid": "21002929", "title": "THE present position in Britain.", "content": "THE present position in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002929"}
{"pmid": "21002930", "title": "The importance of international biological standards in pharmacy.", "content": "The importance of international biological standards in pharmacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002930"}
{"pmid": "21002931", "title": "NEW B. Pharm. degree.", "content": "NEW B. Pharm. degree.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002931"}
{"pmid": "21002932", "title": "Improvised pharmaceutical work in Malaya.", "content": "Improvised pharmaceutical work in Malaya.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002932"}
{"pmid": "21002933", "title": "Penicillin; its properties, uses and preparations.", "content": "Penicillin; its properties, uses and preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002933"}
{"pmid": "21002934", "title": "A simple all-glass water still.", "content": "A simple all-glass water still.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002934"}
{"pmid": "21002935", "title": "CONTROL of insects in stored products.", "content": "CONTROL of insects in stored products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002935"}
{"pmid": "21002936", "title": "Changes in blood acid-base balance during asphyxia and resuscitation.", "content": "Changes in blood acid-base balance during asphyxia and resuscitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002936"}
{"pmid": "21002937", "title": "The effects of hemorrhage on tissue metabolites.", "content": "The effects of hemorrhage on tissue metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002937"}
{"pmid": "21002938", "title": "Effect of bilateral destruction of three lateral cerebral cortical areas on current conditioned differential responses from general cutaneous stimulation.", "content": "Effect of bilateral destruction of three lateral cerebral cortical areas on current conditioned differential responses from general cutaneous stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002938"}
{"pmid": "21002939", "title": "The metabolism of histamine and adenylic compounds in the embryo.", "content": "The metabolism of histamine and adenylic compounds in the embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002939"}
{"pmid": "21002940", "title": "The influence of steroids on the restoration of hypertension in hypophysectomized rats.", "content": "The influence of steroids on the restoration of hypertension in hypophysectomized rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002940"}
{"pmid": "21002941", "title": "The electrocardiogram of rats on vitamin E deficiency.", "content": "The electrocardiogram of rats on vitamin E deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002941"}
{"pmid": "21002942", "title": "Factors governing the rate of excretion of titratable acid in the dog.", "content": "Factors governing the rate of excretion of titratable acid in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002942"}
{"pmid": "21002943", "title": "The simultaneous transport of T-1824 and radioactive red cells through the heart and lungs.", "content": "The simultaneous transport of T-1824 and radioactive red cells through the heart and lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002943"}
{"pmid": "21002944", "title": "Further observations on the distribution at the level of the pons of descending nerve fibers subserving heat regulating functions.", "content": "Further observations on the distribution at the level of the pons of descending nerve fibers subserving heat regulating functions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002944"}
{"pmid": "21002945", "title": "The effect of various ions on the anaerobic glycolysis of rat liver in vitro.", "content": "The effect of various ions on the anaerobic glycolysis of rat liver in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002945"}
{"pmid": "21002947", "title": "The relationship of the parathyroid glands to the action of estrogen on bone.", "content": "The relationship of the parathyroid glands to the action of estrogen on bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002947"}
{"pmid": "21002946", "title": "The validity of internal jugular venous blood in studies of cerebral metabolism and blood flow in man.", "content": "The validity of internal jugular venous blood in studies of cerebral metabolism and blood flow in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002946"}
{"pmid": "21002948", "title": "The effect of dinitrophenol on the oxygen consumption of albino mice at graded levels of environmental temperature.", "content": "The effect of dinitrophenol on the oxygen consumption of albino mice at graded levels of environmental temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002948"}
{"pmid": "21002949", "title": "Tolerance of adult chickens to hypothermia.", "content": "Tolerance of adult chickens to hypothermia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002949"}
{"pmid": "21002950", "title": "The relation of renal blood flow to effective arterial pressure in the intact kidney of the dog.", "content": "The relation of renal blood flow to effective arterial pressure in the intact kidney of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002950"}
{"pmid": "21002951", "title": "A study of nerve degeneration and regeneration.", "content": "A study of nerve degeneration and regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002951"}
{"pmid": "21002952", "title": "Relative potency of certain synthetic estrogens when administered orally to chicks.", "content": "Relative potency of certain synthetic estrogens when administered orally to chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002952"}
{"pmid": "21002953", "title": "Standardized hemorrhagic shock in the guinea pig.", "content": "Standardized hemorrhagic shock in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002953"}
{"pmid": "21002954", "title": "The effect of ascorbic acid on hemorrhagic shock in the guinea pig.", "content": "The effect of ascorbic acid on hemorrhagic shock in the guinea pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002954"}
{"pmid": "21002955", "title": "The action of quinine on dehydrogenases of E. coli.", "content": "The action of quinine on dehydrogenases of E. coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002955"}
{"pmid": "21002956", "title": "The disinfection of E. coli in relation to temperature, hydrostatic pressure and quinine.", "content": "The disinfection of E. coli in relation to temperature, hydrostatic pressure and quinine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002956"}
{"pmid": "21002962", "title": "The absorption of estriol by the plasma proteins.", "content": "The absorption of estriol by the plasma proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002962"}
{"pmid": "21002957", "title": "The growth rate of E. coli in relation to temperature, quinine and coenzyme.", "content": "The growth rate of E. coli in relation to temperature, quinine and coenzyme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002957"}
{"pmid": "21002970", "title": "Biotin and the avidin-biotin complex.", "content": "Biotin and the avidin-biotin complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002970"}
{"pmid": "21002959", "title": "Membrane potentials and excitation of impaled single muscle fibers.", "content": "Membrane potentials and excitation of impaled single muscle fibers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002959"}
{"pmid": "21002971", "title": "The metabolism and permeability of normal skin.", "content": "The metabolism and permeability of normal skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002971"}
{"pmid": "21002961", "title": "The histochemical localization of glycogen in the developing tooth.", "content": "The histochemical localization of glycogen in the developing tooth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002961"}
{"pmid": "21002972", "title": "Mechanism of the development of obesity in animals with hypothalamic lesions.", "content": "Mechanism of the development of obesity in animals with hypothalamic lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002972"}
{"pmid": "21002960", "title": "An intracellular photodynamic sensitizer in blepharisma.", "content": "An intracellular photodynamic sensitizer in blepharisma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002960"}
{"pmid": "21002973", "title": "Carbonic anhydrase in tissues other than blood.", "content": "Carbonic anhydrase in tissues other than blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002973"}
{"pmid": "21002974", "title": "Preparation and chemistry of anterior pituitary hormones.", "content": "Preparation and chemistry of anterior pituitary hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002974"}
{"pmid": "21002958", "title": "The influence of pressure, temperature, and quinine on the rates of growth and disinfection of E. coli in the logarithmic growth phase.", "content": "The influence of pressure, temperature, and quinine on the rates of growth and disinfection of E. coli in the logarithmic growth phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002958"}
{"pmid": "21002975", "title": "Organization of the respiratory center.", "content": "Organization of the respiratory center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002975"}
{"pmid": "21002976", "title": "Studies of abnormal behavior in the rat; water spray as a means of inducing seizures.", "content": "Studies of abnormal behavior in the rat; water spray as a means of inducing seizures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002976"}
{"pmid": "21002964", "title": "Acetylcholine and related substances in the cockroach, fly and crayfish and the effect of DDT.", "content": "Acetylcholine and related substances in the cockroach, fly and crayfish and the effect of DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002964"}
{"pmid": "21002963", "title": "A histochemical test for arginine-rich proteins.", "content": "A histochemical test for arginine-rich proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002963"}
{"pmid": "21002977", "title": "Retroactive inhibition or facilitation from interpolated learning as a function of time.", "content": "Retroactive inhibition or facilitation from interpolated learning as a function of time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002977"}
{"pmid": "21002978", "title": "Purposive avoidance reaction to electric shock.", "content": "Purposive avoidance reaction to electric shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002978"}
{"pmid": "21002965", "title": "A study of the enzymatic and other properties of the crystalline style of clams; evidence for the presence of a cellulase.", "content": "A study of the enzymatic and other properties of the crystalline style of clams; evidence for the presence of a cellulase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002965"}
{"pmid": "21002968", "title": "Phosphorylation in living yeast cells.", "content": "Phosphorylation in living yeast cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002968"}
{"pmid": "21002969", "title": "The relationship of potassium to carbohydrate metabolism in baker's yeast.", "content": "The relationship of potassium to carbohydrate metabolism in baker's yeast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002969"}
{"pmid": "21002967", "title": "Localization of acid and alkaline phosphomonesterases in cytoplasmic granules.", "content": "Localization of acid and alkaline phosphomonesterases in cytoplasmic granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002967"}
{"pmid": "21002966", "title": "Alkaline and acid phosphomonoesterase activity in chick embryos.", "content": "Alkaline and acid phosphomonoesterase activity in chick embryos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002966"}
{"pmid": "21002989", "title": "Factors influencing performance on group and individual tests of intelligence; social facilitation.", "content": "Factors influencing performance on group and individual tests of intelligence; social facilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002989"}
{"pmid": "21002990", "title": "A study of the sociometric process among sixth-grade children.", "content": "A study of the sociometric process among sixth-grade children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002990"}
{"pmid": "21002991", "title": "The relationship between perceptual span and rate of reading.", "content": "The relationship between perceptual span and rate of reading.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002991"}
{"pmid": "21002979", "title": "The development of psychological internship training.", "content": "The development of psychological internship training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002979"}
{"pmid": "21002992", "title": "A study comparing art abilities and general intelligence of college students.", "content": "A study comparing art abilities and general intelligence of college students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002992"}
{"pmid": "21002980", "title": "Internship program at the Vineland Laboratory.", "content": "Internship program at the Vineland Laboratory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002980"}
{"pmid": "21002993", "title": "An analytic study of the multiple choice analogies test item.", "content": "An analytic study of the multiple choice analogies test item.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002993"}
{"pmid": "21002994", "title": "Further evidence on the unexpected large size of recognition vocabularies among college students.", "content": "Further evidence on the unexpected large size of recognition vocabularies among college students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002994"}
{"pmid": "21002981", "title": "The Worcester internship program.", "content": "The Worcester internship program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002981"}
{"pmid": "21002985", "title": "A state-wide program for a practicum course in clinical psychology.", "content": "A state-wide program for a practicum course in clinical psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002985"}
{"pmid": "21002995", "title": "A sequence concept of attitude.", "content": "A sequence concept of attitude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002995"}
{"pmid": "21002996", "title": "Quantification of electroencephalography.", "content": "Quantification of electroencephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002996"}
{"pmid": "21002986", "title": "Graduate internships in psychology at the Western State Psychiatric Institute and Clinic.", "content": "Graduate internships in psychology at the Western State Psychiatric Institute and Clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002986"}
{"pmid": "21002987", "title": "The clinical training of fellows-in-psychology.", "content": "The clinical training of fellows-in-psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002987"}
{"pmid": "21002997", "title": "Electroencephalographic studies of mental fatigue.", "content": "Electroencephalographic studies of mental fatigue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002997"}
{"pmid": "21002983", "title": "Psychological externships at the Michael Reese Hospital.", "content": "Psychological externships at the Michael Reese Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002983"}
{"pmid": "21002998", "title": "Effects of electro-convulsive shocks on reasoning ability in albino rats.", "content": "Effects of electro-convulsive shocks on reasoning ability in albino rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002998"}
{"pmid": "21002982", "title": "The New York State Psychological Intern Training Program; development of a rotating internship in psychology.", "content": "The New York State Psychological Intern Training Program; development of a rotating internship in psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002982"}
{"pmid": "21002999", "title": "An alternate form of the Wechsler Memory Scale.", "content": "An alternate form of the Wechsler Memory Scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002999"}
{"pmid": "21002984", "title": "The psychological internship training program of the Menninger Clinic.", "content": "The psychological internship training program of the Menninger Clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002984"}
{"pmid": "21003000", "title": "Psychological determinants of optimism regarding consequences of the war.", "content": "Psychological determinants of optimism regarding consequences of the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003000"}
{"pmid": "21003001", "title": "The relationship between intelligence and motor learning ability, as measured by a high relief finger maze.", "content": "The relationship between intelligence and motor learning ability, as measured by a high relief finger maze.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003001"}
{"pmid": "21002988", "title": "Supervised training in a college counseling bureau.", "content": "Supervised training in a college counseling bureau.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21002988"}
{"pmid": "21003002", "title": "Measurement of neurotic tendency in Negro students of music.", "content": "Measurement of neurotic tendency in Negro students of music.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003002"}
{"pmid": "21003003", "title": "Estimation of Rorschach scoring categories by means of an objective inventory.", "content": "Estimation of Rorschach scoring categories by means of an objective inventory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003003"}
{"pmid": "21003004", "title": "Origen; his contribution to the study of imagination.", "content": "Origen; his contribution to the study of imagination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003004"}
{"pmid": "21003005", "title": "Two kinds of learning.", "content": "Two kinds of learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003005"}
{"pmid": "21003006", "title": "The relationship of Bernreuter scores to parent behavior, child behavior, urban-rural residence, and other background factors in 100 normal adult parents.", "content": "The relationship of Bernreuter scores to parent behavior, child behavior, urban-rural residence, and other background factors in 100 normal adult parents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003006"}
{"pmid": "21003007", "title": "What is intelligence?", "content": "What is intelligence?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003007"}
{"pmid": "21003008", "title": "Are Jewish or Gentile children more clannish?", "content": "Are Jewish or Gentile children more clannish?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003008"}
{"pmid": "21003009", "title": "Identifiability of nationality characteristics.", "content": "Identifiability of nationality characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003009"}
{"pmid": "21003010", "title": "Toward an occupational social psychology.", "content": "Toward an occupational social psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003010"}
{"pmid": "21003011", "title": "A study of the factors in the identification of handwriting.", "content": "A study of the factors in the identification of handwriting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003011"}
{"pmid": "21003012", "title": "Health indices in relation to age, sex, race and socio-economic status.", "content": "Health indices in relation to age, sex, race and socio-economic status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003012"}
{"pmid": "21003013", "title": "Some aspects in the occupational adjustment of the blind.", "content": "Some aspects in the occupational adjustment of the blind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003013"}
{"pmid": "21003014", "title": "Simplified factor analysis.", "content": "Simplified factor analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003014"}
{"pmid": "21003015", "title": "Epidemic pneumococcal pneumonia; description of the epidemic.", "content": "Epidemic pneumococcal pneumonia; description of the epidemic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003015"}
{"pmid": "21003016", "title": "Epidemic pneumococcal pneumonia; the influence of population characteristics and environment.", "content": "Epidemic pneumococcal pneumonia; the influence of population characteristics and environment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003016"}
{"pmid": "21003017", "title": "Epidemic pneumococcal pneumonia; pneumococcal carrier studies.", "content": "Epidemic pneumococcal pneumonia; pneumococcal carrier studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003017"}
{"pmid": "21003018", "title": "Epidemic pneumococcal pneumonia; the relationship of nonbacterial respiratory disease to pneumococcal pneumonia.", "content": "Epidemic pneumococcal pneumonia; the relationship of nonbacterial respiratory disease to pneumococcal pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003018"}
{"pmid": "21003019", "title": "Epidemic pneumococcal pneumonia; final consideration of the factors underlying the epidemic.", "content": "Epidemic pneumococcal pneumonia; final consideration of the factors underlying the epidemic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003019"}
{"pmid": "21003020", "title": "The serological detection of murine typhus in flea feces.", "content": "The serological detection of murine typhus in flea feces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003020"}
{"pmid": "21003021", "title": "The effect of dietary carbohydrates on the dental flora of the rat.", "content": "The effect of dietary carbohydrates on the dental flora of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003021"}
{"pmid": "21003023", "title": "Plasmodium elongatum in the Pekin duck.", "content": "Plasmodium elongatum in the Pekin duck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003023"}
{"pmid": "21003022", "title": "The epidemiology of acute respiratory infections conditioned by sulfonamides; effects of sulfadiazine on groups A and G hemolytic streptococci.", "content": "The epidemiology of acute respiratory infections conditioned by sulfonamides; effects of sulfadiazine on groups A and G hemolytic streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003022"}
{"pmid": "21003024", "title": "Studies of Plasmodium cynomolgi in the rhesus monkey, Macaca mulatta.", "content": "Studies of Plasmodium cynomolgi in the rhesus monkey, Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003024"}
{"pmid": "21003025", "title": "Relationship between the number of parasites and parasitized erythrocytes in avian and simian malaria.", "content": "Relationship between the number of parasites and parasitized erythrocytes in avian and simian malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003025"}
{"pmid": "21003030", "title": "Treatment of pediculus capitis in school children with DDT powder.", "content": "Treatment of pediculus capitis in school children with DDT powder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003030"}
{"pmid": "21003041", "title": "An analysis of the effect of fat in the diet on recovery in infectious hepatitis.", "content": "An analysis of the effect of fat in the diet on recovery in infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003041"}
{"pmid": "21003043", "title": "Work of the Interstate Sanitation Commission.", "content": "Work of the Interstate Sanitation Commission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003043"}
{"pmid": "21003045", "title": "A reverse approach to the fluorine-dental caries hypothesis.", "content": "A reverse approach to the fluorine-dental caries hypothesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003045"}
{"pmid": "21003050", "title": "Supervision of health in small plants.", "content": "Supervision of health in small plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003050"}
{"pmid": "21003051", "title": "Nutritional aspects of the Hartman Jones Memorial School health study.", "content": "Nutritional aspects of the Hartman Jones Memorial School health study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003051"}
{"pmid": "21003052", "title": "Treatment of personnel of the Merchant Marine during the war.", "content": "Treatment of personnel of the Merchant Marine during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003052"}
{"pmid": "21003053", "title": "REPORT of the committee on the Form and Content of Annual Vital Statistics Reports.", "content": "REPORT of the committee on the Form and Content of Annual Vital Statistics Reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003053"}
{"pmid": "21003055", "title": "TWENTY-FIFTH anniversary of the discovery of insulin.", "content": "TWENTY-FIFTH anniversary of the discovery of insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003055"}
{"pmid": "21003054", "title": "Studies of the serology of typhus fever; complement-fixing antigens of Rickettsia Prowazeki and their relationship to Proteus 0X19.", "content": "Studies of the serology of typhus fever; complement-fixing antigens of Rickettsia Prowazeki and their relationship to Proteus 0X19.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003054"}
{"pmid": "21003056", "title": "The diphtheria situation in Cape Breton Island, Nova Scotia, over a two-year period.", "content": "The diphtheria situation in Cape Breton Island, Nova Scotia, over a two-year period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003056"}
{"pmid": "21003057", "title": "Nutritional aspects of a school health study in Marysville, New Brunswick.", "content": "Nutritional aspects of a school health study in Marysville, New Brunswick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003057"}
{"pmid": "21003058", "title": "Mortality reductions in Ontario, 1900-42; scarlet fever.", "content": "Mortality reductions in Ontario, 1900-42; scarlet fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003058"}
{"pmid": "21003059", "title": "Studies of the serology of typhus fever; complement-fixing antibody response to vaccination and to infection.", "content": "Studies of the serology of typhus fever; complement-fixing antibody response to vaccination and to infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003059"}
{"pmid": "21003060", "title": "Studies in the dynamics of disinfection; the reaction between phenol and Bact. coli; the effect of temperature on the usually accepted concentration exponent and the calculation of a more satisfactory exponent based on theoretical considerations.", "content": "Studies in the dynamics of disinfection; the reaction between phenol and Bact. coli; the effect of temperature on the usually accepted concentration exponent and the calculation of a more satisfactory exponent based on theoretical considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003060"}
{"pmid": "21003068", "title": "Feeding and breeding of laboratory animals; rat and mouse cubes, and cube containers.", "content": "Feeding and breeding of laboratory animals; rat and mouse cubes, and cube containers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003068"}
{"pmid": "21003069", "title": "Feeding and breeding of laboratory animals; growth and maintenance of rabbits without fresh green food.", "content": "Feeding and breeding of laboratory animals; growth and maintenance of rabbits without fresh green food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003069"}
{"pmid": "21003071", "title": "Endemic pellagra in northern Portugal.", "content": "Endemic pellagra in northern Portugal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003071"}
{"pmid": "21003072", "title": "Memorandum on B. C. G.", "content": "Memorandum on B. C. G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003072"}
{"pmid": "21003073", "title": "Hygiene of crew quarters.", "content": "Hygiene of crew quarters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003073"}
{"pmid": "21003075", "title": "PUBLIC health during six years of war.", "content": "PUBLIC health during six years of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003075"}
{"pmid": "21003074", "title": "The present status of vaccination against influenza.", "content": "The present status of vaccination against influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003074"}
{"pmid": "21003076", "title": "Nation and family; the Swedish experiment in democratic family and population policy.", "content": "Nation and family; the Swedish experiment in democratic family and population policy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003076"}
{"pmid": "21003078", "title": "DEGREES and diplomas in public health.", "content": "DEGREES and diplomas in public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003078"}
{"pmid": "21003077", "title": "The public health service as a career.", "content": "The public health service as a career.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003077"}
{"pmid": "21003079", "title": "War conditions and tuberculosis in Birmingham.", "content": "War conditions and tuberculosis in Birmingham.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003079"}
{"pmid": "21003080", "title": "An enquiry into the problem of the arrest in the decline in mortality from tuberculosis in the 15-25 age group during the early part of the present century.", "content": "An enquiry into the problem of the arrest in the decline in mortality from tuberculosis in the 15-25 age group during the early part of the present century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003080"}
{"pmid": "21003081", "title": "The World Health Organisation of the future.", "content": "The World Health Organisation of the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003081"}
{"pmid": "21003082", "title": "Some results of anisometropia.", "content": "Some results of anisometropia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003082"}
{"pmid": "21003083", "title": "Isolation hospital accommodation in Bristol from 1921 to 1945.", "content": "Isolation hospital accommodation in Bristol from 1921 to 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003083"}
{"pmid": "21003084", "title": "Physical training and the posture of the Norwegian child.", "content": "Physical training and the posture of the Norwegian child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003084"}
{"pmid": "21003085", "title": "Civil defence measures in Westminister, 1939-1945.", "content": "Civil defence measures in Westminister, 1939-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003085"}
{"pmid": "21003086", "title": "INFANTILE paralysis, or acute poliomyelitis; a brief primer of the disease and its treatment.", "content": "INFANTILE paralysis, or acute poliomyelitis; a brief primer of the disease and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003086"}
{"pmid": "21003087", "title": "Contributory factors in the national health outlook.", "content": "Contributory factors in the national health outlook.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003087"}
{"pmid": "21003088", "title": "The future of nursing services.", "content": "The future of nursing services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003088"}
{"pmid": "21003089", "title": "Observations on venereal disease.", "content": "Observations on venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003089"}
{"pmid": "21003090", "title": "Housing problems in a rural area.", "content": "Housing problems in a rural area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003090"}
{"pmid": "21003091", "title": "Drainage and sewerage for rural housing.", "content": "Drainage and sewerage for rural housing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003091"}
{"pmid": "21003092", "title": "The effects of enemy occupation on the dental condition of children in the Channel Islands.", "content": "The effects of enemy occupation on the dental condition of children in the Channel Islands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003092"}
{"pmid": "21003093", "title": "Cancer mortality in England and Wales.", "content": "Cancer mortality in England and Wales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003093"}
{"pmid": "21003094", "title": "Meningitis due to Salm. paratyphi C.", "content": "Meningitis due to Salm. paratyphi C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003094"}
{"pmid": "21003095", "title": "A post-nasal swab suitable for culturing Haemophilus pertussis.", "content": "A post-nasal swab suitable for culturing Haemophilus pertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003095"}
{"pmid": "21003097", "title": "War and the nutritional state.", "content": "War and the nutritional state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003097"}
{"pmid": "21003096", "title": "The evaluation of infant health services.", "content": "The evaluation of infant health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003096"}
{"pmid": "21003098", "title": "The planning of hostels for unmarried mothers.", "content": "The planning of hostels for unmarried mothers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003098"}
{"pmid": "21003099", "title": "An outbreak of typhoid fever in the East Midlands.", "content": "An outbreak of typhoid fever in the East Midlands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003099"}
{"pmid": "21003100", "title": "Burns and scalds in the home.", "content": "Burns and scalds in the home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003100"}
{"pmid": "21003101", "title": "The control of ice-cream.", "content": "The control of ice-cream.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003101"}
{"pmid": "21003102", "title": "The decline of mortality from rheumatic fever.", "content": "The decline of mortality from rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003102"}
{"pmid": "21003103", "title": "Staphylococcus aureus in cows' milk; the results of phage-typing.", "content": "Staphylococcus aureus in cows' milk; the results of phage-typing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003103"}
{"pmid": "21003104", "title": "Notes on H. parapertussis.", "content": "Notes on H. parapertussis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003104"}
{"pmid": "21003105", "title": "What is early tuberculosis?", "content": "What is early tuberculosis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003105"}
{"pmid": "21003106", "title": "Physical fitness of men entering the Army Air Forces.", "content": "Physical fitness of men entering the Army Air Forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003106"}
{"pmid": "21003107", "title": "The relationship of recreational participation to industrial efficiency.", "content": "The relationship of recreational participation to industrial efficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003107"}
{"pmid": "21003108", "title": "A study of some relationships between performance tests and certain physiological measures associated with maximal and submaximal work.", "content": "A study of some relationships between performance tests and certain physiological measures associated with maximal and submaximal work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003108"}
{"pmid": "21003109", "title": "Proeven over zelfreiniging van stroom end water.", "content": "Proeven over zelfreiniging van stroom end water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003109"}
{"pmid": "21003110", "title": "Angiographic diagnosis of expanding intracranial lesions by vascular displacement.", "content": "Angiographic diagnosis of expanding intracranial lesions by vascular displacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003110"}
{"pmid": "21003111", "title": "Pulmonary adenomatosis.", "content": "Pulmonary adenomatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003111"}
{"pmid": "21003112", "title": "Retrograde abdominal aortography; a contribution to the study of the abdominal aorta and iliac arteries.", "content": "Retrograde abdominal aortography; a contribution to the study of the abdominal aorta and iliac arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003112"}
{"pmid": "21003113", "title": "Bilateral osteochondritis dissecans of the knee.", "content": "Bilateral osteochondritis dissecans of the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003113"}
{"pmid": "21003114", "title": "Heart size from routine chest films.", "content": "Heart size from routine chest films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003114"}
{"pmid": "21003115", "title": "Determination of frontal plane area from the product of the long and short diameters of the cardiac silhouette.", "content": "Determination of frontal plane area from the product of the long and short diameters of the cardiac silhouette.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003115"}
{"pmid": "21003116", "title": "Esophagopleural fistula complicating empyema.", "content": "Esophagopleural fistula complicating empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003116"}
{"pmid": "21003117", "title": "The use of pyridoxine hydrochloride in radiation sickness.", "content": "The use of pyridoxine hydrochloride in radiation sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003117"}
{"pmid": "21003118", "title": "Peroral administration of vitamin B6 (pyridoxine hydrochloride) in the treatment of radiation sickness.", "content": "Peroral administration of vitamin B6 (pyridoxine hydrochloride) in the treatment of radiation sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003118"}
{"pmid": "21003119", "title": "Pyridoxine hydrochloride (vitamin B6) in the control of radiation sickness; preliminary report.", "content": "Pyridoxine hydrochloride (vitamin B6) in the control of radiation sickness; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003119"}
{"pmid": "21003120", "title": "Treatment of radiation sickness with trasentine and trasentine-phenobarbital; preliminary report.", "content": "Treatment of radiation sickness with trasentine and trasentine-phenobarbital; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003120"}
{"pmid": "21003121", "title": "A simple accurate fluoroscopic method of foreign body localization.", "content": "A simple accurate fluoroscopic method of foreign body localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003121"}
{"pmid": "21003122", "title": "Medical and hospital insurance problems.", "content": "Medical and hospital insurance problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003122"}
{"pmid": "21003123", "title": "Evaluation of common procedures in mammaplasty and a new technic.", "content": "Evaluation of common procedures in mammaplasty and a new technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003123"}
{"pmid": "21003124", "title": "War wounds of the abdomen; a review of 131 cases.", "content": "War wounds of the abdomen; a review of 131 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003124"}
{"pmid": "21003125", "title": "The foot problem as seen in soldiers.", "content": "The foot problem as seen in soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003125"}
{"pmid": "21003126", "title": "Surgical aspects of carcinoma of the stomach.", "content": "Surgical aspects of carcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003126"}
{"pmid": "21003127", "title": "Indications for determination of the thickness of split skin grafts.", "content": "Indications for determination of the thickness of split skin grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003127"}
{"pmid": "21003128", "title": "Refrigeration in surgery.", "content": "Refrigeration in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003128"}
{"pmid": "21003129", "title": "Source of nerve autografts in clinical surgery; technic for their suture.", "content": "Source of nerve autografts in clinical surgery; technic for their suture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003129"}
{"pmid": "21003130", "title": "The local use of ice after orthopedic procedures.", "content": "The local use of ice after orthopedic procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003130"}
{"pmid": "21003131", "title": "Transscrotal orchidopexy in adults.", "content": "Transscrotal orchidopexy in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003131"}
{"pmid": "21003132", "title": "A comparison of intravenous aminophyllin with the common drugs in biliary colic.", "content": "A comparison of intravenous aminophyllin with the common drugs in biliary colic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003132"}
{"pmid": "21003133", "title": "External skeletal fixation of fractures.", "content": "External skeletal fixation of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003133"}
{"pmid": "21003134", "title": "Conservative treatment of thyrotoxicosis with thiouracil.", "content": "Conservative treatment of thyrotoxicosis with thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003134"}
{"pmid": "21003135", "title": "The management of carcinoma of the colon in a small general hospital.", "content": "The management of carcinoma of the colon in a small general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003135"}
{"pmid": "21003136", "title": "Vaginoplasty.", "content": "Vaginoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003136"}
{"pmid": "21003138", "title": "Surgical removal of leiomyomas of the esophagus.", "content": "Surgical removal of leiomyomas of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003138"}
{"pmid": "21003137", "title": "Intradermal sensitivity test for amino acids.", "content": "Intradermal sensitivity test for amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003137"}
{"pmid": "21003139", "title": "Pneumococcal arthritis.", "content": "Pneumococcal arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003139"}
{"pmid": "21003140", "title": "Abdominal skeletonized fetus with uteroperitoneal fistula secondary to criminal abortion.", "content": "Abdominal skeletonized fetus with uteroperitoneal fistula secondary to criminal abortion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003140"}
{"pmid": "21003141", "title": "Skeletal traction in the treatment of multiple fractures of the thoracic cage.", "content": "Skeletal traction in the treatment of multiple fractures of the thoracic cage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003141"}
{"pmid": "21003142", "title": "Barium as a factor in intestinal obstruction.", "content": "Barium as a factor in intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003142"}
{"pmid": "21003144", "title": "A simple uterine sound marker.", "content": "A simple uterine sound marker.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003144"}
{"pmid": "21003143", "title": "Metacarpal fractures; a new instrument for the maintenance of position after reduction.", "content": "Metacarpal fractures; a new instrument for the maintenance of position after reduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003143"}
{"pmid": "21003145", "title": "Cassette holder for the Hawley table.", "content": "Cassette holder for the Hawley table.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003145"}
{"pmid": "21003152", "title": "Ureterointestinal anastomosis.", "content": "Ureterointestinal anastomosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003152"}
{"pmid": "21003176", "title": "The management of penetrating wounds and suppurative arthritis of the knee joint in the Mediterranean Theater of Operations.", "content": "The management of penetrating wounds and suppurative arthritis of the knee joint in the Mediterranean Theater of Operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003176"}
{"pmid": "21003177", "title": "Skin-grafting in the treatment of osteomyelitic war wounds.", "content": "Skin-grafting in the treatment of osteomyelitic war wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003177"}
{"pmid": "21003178", "title": "Restoration of bone strength with reinforcement bone grafts.", "content": "Restoration of bone strength with reinforcement bone grafts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003178"}
{"pmid": "21003179", "title": "The surgical principles of split-thickness-skin grafting.", "content": "The surgical principles of split-thickness-skin grafting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003179"}
{"pmid": "21003180", "title": "Neurectomy to produce atrophy of the amputation stump.", "content": "Neurectomy to produce atrophy of the amputation stump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003180"}
{"pmid": "21003181", "title": "The multiple innervation of limb muscles in man.", "content": "The multiple innervation of limb muscles in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003181"}
{"pmid": "21003182", "title": "Active splinting of the hand.", "content": "Active splinting of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003182"}
{"pmid": "21003183", "title": "A study of supination and pronation, with especial reference to the treatment of forearm fractures.", "content": "A study of supination and pronation, with especial reference to the treatment of forearm fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003183"}
{"pmid": "21003184", "title": "End results of bone-grafting for non-union of the carpal navicular.", "content": "End results of bone-grafting for non-union of the carpal navicular.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003184"}
{"pmid": "21003185", "title": "An operation for non-union of fractures of the carpal navicular.", "content": "An operation for non-union of fractures of the carpal navicular.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003185"}
{"pmid": "21003186", "title": "The conservative treatment of congenital talipes equinovarus.", "content": "The conservative treatment of congenital talipes equinovarus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003186"}
{"pmid": "21003187", "title": "A splint for treatment of recurrent club-foot.", "content": "A splint for treatment of recurrent club-foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003187"}
{"pmid": "21003188", "title": "The treatment of paralytic calcaneus.", "content": "The treatment of paralytic calcaneus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003188"}
{"pmid": "21003189", "title": "Treatment of congenital flat-foot.", "content": "Treatment of congenital flat-foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003189"}
{"pmid": "21003190", "title": "Internal fixation of trochanteric fractures of the femur; report of 103 consecutive cases.", "content": "Internal fixation of trochanteric fractures of the femur; report of 103 consecutive cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003190"}
{"pmid": "21003191", "title": "Paget's disease; a statistica study of eighty-two cases.", "content": "Paget's disease; a statistica study of eighty-two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003191"}
{"pmid": "21003192", "title": "Posterior approach to the superolateral region of the tibia.", "content": "Posterior approach to the superolateral region of the tibia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003192"}
{"pmid": "21003193", "title": "A surgical procedure for repair of recurrent dislocation of the shoulder joint; a preliminary report.", "content": "A surgical procedure for repair of recurrent dislocation of the shoulder joint; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003193"}
{"pmid": "21003194", "title": "Complete dislocations of the acromiclavicular joint; the nature of the traumatic lesion and effective methods of treatment with an analysis of forty-one cases.", "content": "Complete dislocations of the acromiclavicular joint; the nature of the traumatic lesion and effective methods of treatment with an analysis of forty-one cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003194"}
{"pmid": "21003195", "title": "Obstetrical dislocation of the hip associated with fracture of the femur.", "content": "Obstetrical dislocation of the hip associated with fracture of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003195"}
{"pmid": "21003196", "title": "Panner's metatarsal disease; a condition of aseptic necrosis simulating march fracture.", "content": "Panner's metatarsal disease; a condition of aseptic necrosis simulating march fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003196"}
{"pmid": "21003197", "title": "The supra condyloid process of the humerus.", "content": "The supra condyloid process of the humerus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003197"}
{"pmid": "21003198", "title": "Osteotomy of the lumbar spine for correction of kyphosis in a case of ankylosing spondylarthritis.", "content": "Osteotomy of the lumbar spine for correction of kyphosis in a case of ankylosing spondylarthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003198"}
{"pmid": "21003199", "title": "Recurrent dislocation of the first carpometacarpal joint repaired by functional tenodesis.", "content": "Recurrent dislocation of the first carpometacarpal joint repaired by functional tenodesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003199"}
{"pmid": "21003200", "title": "Non-union of the ischial tuberosity associated with epiphysitis vertebrae; report of a case.", "content": "Non-union of the ischial tuberosity associated with epiphysitis vertebrae; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003200"}
{"pmid": "21003201", "title": "Transpleural rupture of a tuberculous spinal abscess treated successfully by streptomycin.", "content": "Transpleural rupture of a tuberculous spinal abscess treated successfully by streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003201"}
{"pmid": "21003202", "title": "Epiphyse coxa valga; report of two cases.", "content": "Epiphyse coxa valga; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003202"}
{"pmid": "21003203", "title": "Unusual regeneration of bone in a child.", "content": "Unusual regeneration of bone in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003203"}
{"pmid": "21003204", "title": "March foot in a seven-year-old child.", "content": "March foot in a seven-year-old child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003204"}
{"pmid": "21003205", "title": "Carcinoma the colon; analysis of 113 cases.", "content": "Carcinoma the colon; analysis of 113 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003205"}
{"pmid": "21003206", "title": "Practical aspects of the Rh factor.", "content": "Practical aspects of the Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003206"}
{"pmid": "21003207", "title": "The differential diagnosis of intervertebral cartilage ruptures and intraspinal tumors within the lumbar sacral canal.", "content": "The differential diagnosis of intervertebral cartilage ruptures and intraspinal tumors within the lumbar sacral canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003207"}
{"pmid": "21003208", "title": "Treatment of acute hematogenous osteomyelitis.", "content": "Treatment of acute hematogenous osteomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003208"}
{"pmid": "21003209", "title": "Cholelithiasis; modern principles of therapy.", "content": "Cholelithiasis; modern principles of therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003209"}
{"pmid": "21003210", "title": "Charles Jefferson Miller, his teachings in the therapy of puerperal sepsis.", "content": "Charles Jefferson Miller, his teachings in the therapy of puerperal sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003210"}
{"pmid": "21003211", "title": "Historical aspects of aseptic surgical technic.", "content": "Historical aspects of aseptic surgical technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003211"}
{"pmid": "21003212", "title": "Preoperative skin preparation with reference to surface bacteria contaminants and resident flora.", "content": "Preoperative skin preparation with reference to surface bacteria contaminants and resident flora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003212"}
{"pmid": "21003213", "title": "The use of methyl methacrylate plombage in the surgical treatment of pulmonary tuberculosis.", "content": "The use of methyl methacrylate plombage in the surgical treatment of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003213"}
{"pmid": "21003214", "title": "Control of so-called unexplained infections in surgical wounds, with particular reference to thoracic surgery.", "content": "Control of so-called unexplained infections in surgical wounds, with particular reference to thoracic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003214"}
{"pmid": "21003215", "title": "Chest injuries; application of military experience to civilian practice.", "content": "Chest injuries; application of military experience to civilian practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003215"}
{"pmid": "21003216", "title": "Plastic surgery of the breast.", "content": "Plastic surgery of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003216"}
{"pmid": "21003217", "title": "Complications of thoracotomy observed during operations upon the sympathetic and vagus nerves.", "content": "Complications of thoracotomy observed during operations upon the sympathetic and vagus nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003217"}
{"pmid": "21003219", "title": "The surgical treatment of bleeding peptic ulcer.", "content": "The surgical treatment of bleeding peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003219"}
{"pmid": "21003218", "title": "Eosophagogastrostomy for lesions of the upper end of the stomach and lower end of the esophagus.", "content": "Eosophagogastrostomy for lesions of the upper end of the stomach and lower end of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003218"}
{"pmid": "21003220", "title": "The treatment of penetrating wounds of the abdomen in civilian practice.", "content": "The treatment of penetrating wounds of the abdomen in civilian practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003220"}
{"pmid": "21003221", "title": "The management of megacolon (Hirschsprung's disease).", "content": "The management of megacolon (Hirschsprung's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003221"}
{"pmid": "21003222", "title": "Technic of anastomosis of the colon following resection.", "content": "Technic of anastomosis of the colon following resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003222"}
{"pmid": "21003223", "title": "The management of bladder tumors.", "content": "The management of bladder tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003223"}
{"pmid": "21003224", "title": "Cotton sutures in vaginal plastic operations about the bladder and urethra.", "content": "Cotton sutures in vaginal plastic operations about the bladder and urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003224"}
{"pmid": "21003225", "title": "Clearance and saturation tests of renal function.", "content": "Clearance and saturation tests of renal function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003225"}
{"pmid": "21003226", "title": "Unnecessary abdominal operations for pathologic lesions of the genitourinary tract.", "content": "Unnecessary abdominal operations for pathologic lesions of the genitourinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003226"}
{"pmid": "21003227", "title": "The pathology of genitourinary neoplasms.", "content": "The pathology of genitourinary neoplasms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003227"}
{"pmid": "21003228", "title": "The management of bladder neck obstruction.", "content": "The management of bladder neck obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003228"}
{"pmid": "21003229", "title": "Radiosurgery; foreign bodies in the neck removed under fluoroscopic control.", "content": "Radiosurgery; foreign bodies in the neck removed under fluoroscopic control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003229"}
{"pmid": "21003230", "title": "Nutrition in pregnancy; the effects of dietary deficiency in pregnancy and the detection and treatment of nutritional deficiency diseases.", "content": "Nutrition in pregnancy; the effects of dietary deficiency in pregnancy and the detection and treatment of nutritional deficiency diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003230"}
{"pmid": "21003231", "title": "Gastric carcinoma; incidence and diagnostic procedures.", "content": "Gastric carcinoma; incidence and diagnostic procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003231"}
{"pmid": "21003232", "title": "Continuity of the fasciae lining the abdomen, pelvis, and spermatic cord.", "content": "Continuity of the fasciae lining the abdomen, pelvis, and spermatic cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003232"}
{"pmid": "21003233", "title": "Transurethral resection in the surgical management of cord bladder.", "content": "Transurethral resection in the surgical management of cord bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003233"}
{"pmid": "21003234", "title": "Appendicitis in Cleveland; final report.", "content": "Appendicitis in Cleveland; final report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003234"}
{"pmid": "21003235", "title": "Arteriovenous fistulas of the cervical portion of the vertebral vessels.", "content": "Arteriovenous fistulas of the cervical portion of the vertebral vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003235"}
{"pmid": "21003236", "title": "Tendon transplantation in the hand.", "content": "Tendon transplantation in the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003236"}
{"pmid": "21003237", "title": "Further experiences with panlaryngectomy for advanced carcinoma of the larynx.", "content": "Further experiences with panlaryngectomy for advanced carcinoma of the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003237"}
{"pmid": "21003238", "title": "Operative technique of thoracolumbar sympathectomy.", "content": "Operative technique of thoracolumbar sympathectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003238"}
{"pmid": "21003239", "title": "Clinical evaluation of sotradecol, a sodium alkyl sulfate solution, in the injection therapy of varicose veins.", "content": "Clinical evaluation of sotradecol, a sodium alkyl sulfate solution, in the injection therapy of varicose veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003239"}
{"pmid": "21003240", "title": "Therapy for soft tissue sarcomas; an experimental study.", "content": "Therapy for soft tissue sarcomas; an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003240"}
{"pmid": "21003241", "title": "Transthoracic operations for neoplasms of the esophagus and stomach.", "content": "Transthoracic operations for neoplasms of the esophagus and stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003241"}
{"pmid": "21003242", "title": "Vascular injuries in war.", "content": "Vascular injuries in war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003242"}
{"pmid": "21003243", "title": "The development of the graduate training program in surgery.", "content": "The development of the graduate training program in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003243"}
{"pmid": "21003244", "title": "Experiences with cortical excisions for the relief of intractable pain in the extremities.", "content": "Experiences with cortical excisions for the relief of intractable pain in the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003244"}
{"pmid": "21003245", "title": "Megacolon, mechanisms and choice of treatment.", "content": "Megacolon, mechanisms and choice of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003245"}
{"pmid": "21003246", "title": "Arthrodesis of subtalus and midtarsal joints of the foot; historical review, preoperative determinations, and operative procedure.", "content": "Arthrodesis of subtalus and midtarsal joints of the foot; historical review, preoperative determinations, and operative procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003246"}
{"pmid": "21003247", "title": "Adamantinoma of the maxillary sinus.", "content": "Adamantinoma of the maxillary sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003247"}
{"pmid": "21003248", "title": "An operative procedure for the repair of the urethrodiverticulovaginal fistula; report of two cases.", "content": "An operative procedure for the repair of the urethrodiverticulovaginal fistula; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003248"}
{"pmid": "21003249", "title": "Observations on changes in states of mental depression and tension following surgical section of certain frontal lobe pathways.", "content": "Observations on changes in states of mental depression and tension following surgical section of certain frontal lobe pathways.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003249"}
{"pmid": "21003250", "title": "Should we standardize the reconstruction after pancreaticoduodenectomy?", "content": "Should we standardize the reconstruction after pancreaticoduodenectomy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003250"}
{"pmid": "21003251", "title": "The repair of nasal losses.", "content": "The repair of nasal losses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003251"}
{"pmid": "21003252", "title": "The problem of cancer of the breast.", "content": "The problem of cancer of the breast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003252"}
{"pmid": "21003253", "title": "Pilonidal cyst and sinus; a new method of excision with primary closure.", "content": "Pilonidal cyst and sinus; a new method of excision with primary closure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003253"}
{"pmid": "21003254", "title": "Cholecystoduodenocolic membranes.", "content": "Cholecystoduodenocolic membranes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003254"}
{"pmid": "21003255", "title": "Clinical manifestations of lumbar spinal arachnoiditis.", "content": "Clinical manifestations of lumbar spinal arachnoiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003255"}
{"pmid": "21003257", "title": "Multiple invasive carcinomas of the large intestine.", "content": "Multiple invasive carcinomas of the large intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003257"}
{"pmid": "21003256", "title": "Perforation of a duodenal ulcer during roentgen examination.", "content": "Perforation of a duodenal ulcer during roentgen examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003256"}
{"pmid": "21003258", "title": "Exophthalmos and tissue changes in the guinea pig following administration of the thyroid stimulating hormone of the pituitary gland.", "content": "Exophthalmos and tissue changes in the guinea pig following administration of the thyroid stimulating hormone of the pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003258"}
{"pmid": "21003259", "title": "Accessory thyroids in litter-mate pups and in man; their relationship to the development of so-called lateral aberrant thyroid tumors in man.", "content": "Accessory thyroids in litter-mate pups and in man; their relationship to the development of so-called lateral aberrant thyroid tumors in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003259"}
{"pmid": "21003260", "title": "A more optimistic approach to cancer of the thyroid.", "content": "A more optimistic approach to cancer of the thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003260"}
{"pmid": "21003261", "title": "The end results of thyroidectomy in exophthalmic goiter; a 20 years' postoperative study of 100 cases of exophthalmic goiter.", "content": "The end results of thyroidectomy in exophthalmic goiter; a 20 years' postoperative study of 100 cases of exophthalmic goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003261"}
{"pmid": "21003262", "title": "Occupational therapy in cerebral palsy clinics.", "content": "Occupational therapy in cerebral palsy clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003262"}
{"pmid": "21003263", "title": "New hope for the disabled.", "content": "New hope for the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003263"}
{"pmid": "21003264", "title": "Remedial games at the Workmen's Compensation Board Clinic, Toronto.", "content": "Remedial games at the Workmen's Compensation Board Clinic, Toronto.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003264"}
{"pmid": "21003265", "title": "Military amebiasis; observations on the complete courses of forty cases, with results of treatment.", "content": "Military amebiasis; observations on the complete courses of forty cases, with results of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003265"}
{"pmid": "21003266", "title": "The diagnosis of schistosomiasis japonica; technics for the recovery of the eggs of Schistosoma japonicum.", "content": "The diagnosis of schistosomiasis japonica; technics for the recovery of the eggs of Schistosoma japonicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003266"}
{"pmid": "21003267", "title": "The development of the virus of yellow fever in haemagogus mosquitoes.", "content": "The development of the virus of yellow fever in haemagogus mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003267"}
{"pmid": "21003268", "title": "An experiment with neurotropic yellow fever virus in saimiri monkeys and haemagogus mosquitoes.", "content": "An experiment with neurotropic yellow fever virus in saimiri monkeys and haemagogus mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003268"}
{"pmid": "21003270", "title": "The distribution of murine typhus in rats and in humans in San Antonio.", "content": "The distribution of murine typhus in rats and in humans in San Antonio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003270"}
{"pmid": "21003269", "title": "The laboratory transmission of yellow fever virus by Haemagogus splendens.", "content": "The laboratory transmission of yellow fever virus by Haemagogus splendens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003269"}
{"pmid": "21003271", "title": "Pathologic study of natural amebic infection in macaques.", "content": "Pathologic study of natural amebic infection in macaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003271"}
{"pmid": "21003272", "title": "Asiatic cholera; clinical study and experimental therapy with streptomycin.", "content": "Asiatic cholera; clinical study and experimental therapy with streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003272"}
{"pmid": "21003273", "title": "Studies on atabrine (quinacrine) suppression of malaria.", "content": "Studies on atabrine (quinacrine) suppression of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003273"}
{"pmid": "21003274", "title": "Longevity of killing effect of DDT for mosquitoes contacting screen wire painted with DDT solutions.", "content": "Longevity of killing effect of DDT for mosquitoes contacting screen wire painted with DDT solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003274"}
{"pmid": "21003275", "title": "A study of hookworm infection in Navy and Marine personnel on Guam.", "content": "A study of hookworm infection in Navy and Marine personnel on Guam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003275"}
{"pmid": "21003276", "title": "Experiments to determine potential mosquito vectors of Wuchereria bancrofti in the continental United States, Part 2.", "content": "Experiments to determine potential mosquito vectors of Wuchereria bancrofti in the continental United States, Part 2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003276"}
{"pmid": "21003277", "title": "Studies of filariasis; development of Wuchereria bancrofti in Culex quinquefasciatus of Oahu.", "content": "Studies of filariasis; development of Wuchereria bancrofti in Culex quinquefasciatus of Oahu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003277"}
{"pmid": "21003278", "title": "Laboratory studies on the snail host of Schistosoma mansoni.", "content": "Laboratory studies on the snail host of Schistosoma mansoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003278"}
{"pmid": "21003279", "title": "Tolerance of fowl for moderate infections of intestinal helminths.", "content": "Tolerance of fowl for moderate infections of intestinal helminths.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003279"}
{"pmid": "21003280", "title": "Emergency sterilization of drinking water with heteropolar cationic antiseptics; persistence of germicidal action within intestinal tract and removal of excess drug with adsorbing agents.", "content": "Emergency sterilization of drinking water with heteropolar cationic antiseptics; persistence of germicidal action within intestinal tract and removal of excess drug with adsorbing agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003280"}
{"pmid": "21003281", "title": "The causes of death on the Isthmus of Panama; based on 14,304 autopsies performed at the Board of Health Laboratory, Gorgas Hospital, Ancon, Canal Zone, during the forty year period 1904-1944.", "content": "The causes of death on the Isthmus of Panama; based on 14,304 autopsies performed at the Board of Health Laboratory, Gorgas Hospital, Ancon, Canal Zone, during the forty year period 1904-1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003281"}
{"pmid": "21003282", "title": "Human trypanosomiasis and tsetse-flies in Liberia.", "content": "Human trypanosomiasis and tsetse-flies in Liberia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003282"}
{"pmid": "21003283", "title": "Human trypanosomiasis in Liberia, 1941-1944.", "content": "Human trypanosomiasis in Liberia, 1941-1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003283"}
{"pmid": "21003284", "title": "Tsetse-flies in Liberia; distribution and ecology; possibilities of control.", "content": "Tsetse-flies in Liberia; distribution and ecology; possibilities of control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003284"}
{"pmid": "21003285", "title": "The treatment of African sleeping sickness with two new trivalent arsenical preparations (melarsen oxide and 70A).", "content": "The treatment of African sleeping sickness with two new trivalent arsenical preparations (melarsen oxide and 70A).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003285"}
{"pmid": "21003289", "title": "Blackwater fever; modern theories; a critical review.", "content": "Blackwater fever; modern theories; a critical review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003289"}
{"pmid": "21003290", "title": "Helminthiasis; nematodes.", "content": "Helminthiasis; nematodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003290"}
{"pmid": "21003291", "title": "The relationship between primary and adult tuberculosis.", "content": "The relationship between primary and adult tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003291"}
{"pmid": "21003292", "title": "The relationship between primary and adult pulmonary tuberculosis.", "content": "The relationship between primary and adult pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003292"}
{"pmid": "21003293", "title": "Detection of tubercle bacilli by the fluorescence technique.", "content": "Detection of tubercle bacilli by the fluorescence technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003293"}
{"pmid": "21003294", "title": "An experiment in cooperative community organization; from the official viewpoint.", "content": "An experiment in cooperative community organization; from the official viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003294"}
{"pmid": "21003295", "title": "An experiment in cooperative community organization; from the viewpoint of the voluntary agency.", "content": "An experiment in cooperative community organization; from the viewpoint of the voluntary agency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003295"}
{"pmid": "21003296", "title": "Rhode Island serves her youth; a report on the first year's work of the Rhode Island Social Hygiene Association.", "content": "Rhode Island serves her youth; a report on the first year's work of the Rhode Island Social Hygiene Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003296"}
{"pmid": "21003297", "title": "Education for responsible parenthood in Mississippi; a state program to train childre  and young people for emotional and social maturity, as being carried out by the Mississippi Social Hygiene Association.", "content": "Education for responsible parenthood in Mississippi; a state program to train childre  and young people for emotional and social maturity, as being carried out by the Mississippi Social Hygiene Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003297"}
{"pmid": "21003298", "title": "A microflocculation test for syphilis using cardiolipin antigen.", "content": "A microflocculation test for syphilis using cardiolipin antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003298"}
{"pmid": "21003299", "title": "Masking of early syphilis by penicillin therapy in gonorrhea.", "content": "Masking of early syphilis by penicillin therapy in gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003299"}
{"pmid": "21003300", "title": "The effect of the sodium salts of crystalline penicillin G, crystalline penicillin X, and commercial penicillins on darkfield positive lesions of syphilis.", "content": "The effect of the sodium salts of crystalline penicillin G, crystalline penicillin X, and commercial penicillins on darkfield positive lesions of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003300"}
{"pmid": "21003301", "title": "P. B. O. oven.", "content": "P. B. O. oven.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003301"}
{"pmid": "21003302", "title": "Preliminary report on the San Antonio blood test campaign.", "content": "Preliminary report on the San Antonio blood test campaign.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003302"}
{"pmid": "21003303", "title": "A study of syphilis in a Negro high school in the city of Baltimore 1939-1943.", "content": "A study of syphilis in a Negro high school in the city of Baltimore 1939-1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003303"}
{"pmid": "21003304", "title": "Results of rapid treatment of early syphilis.", "content": "Results of rapid treatment of early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003304"}
{"pmid": "21003306", "title": "Self-interview forms in private physician contact reporting; a new technic in case finding.", "content": "Self-interview forms in private physician contact reporting; a new technic in case finding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003306"}
{"pmid": "21003305", "title": "The adequate treatment of gonorrhea.", "content": "The adequate treatment of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003305"}
{"pmid": "21003309", "title": "Experiences with registered letter follow-up in the New York City Health Department.", "content": "Experiences with registered letter follow-up in the New York City Health Department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003309"}
{"pmid": "21003308", "title": "Use of telegrams in venereal disease case holding.", "content": "Use of telegrams in venereal disease case holding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003308"}
{"pmid": "21003307", "title": "Evaluative study of three types of epidemiologic activity on 360 syphilis contacts.", "content": "Evaluative study of three types of epidemiologic activity on 360 syphilis contacts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003307"}
{"pmid": "21003310", "title": "Postgraduate instruction in venereal disease.", "content": "Postgraduate instruction in venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003310"}
{"pmid": "21003311", "title": "The nurse as a case finder in venereal disease.", "content": "The nurse as a case finder in venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003311"}
{"pmid": "21003312", "title": "Venereal disease nursing within industry.", "content": "Venereal disease nursing within industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003312"}
{"pmid": "21003313", "title": "The clinic nurse in venereal disease.", "content": "The clinic nurse in venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003313"}
{"pmid": "21003314", "title": "The public health nurse in the rapid treatment center.", "content": "The public health nurse in the rapid treatment center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003314"}
{"pmid": "21003315", "title": "Should histological terms be included in a revision of the BNA.", "content": "Should histological terms be included in a revision of the BNA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003315"}
{"pmid": "21003316", "title": "Variations of the interosseous muscles of the human foot.", "content": "Variations of the interosseous muscles of the human foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003316"}
{"pmid": "21003317", "title": "The structural response of the parathyroid glands to ureteral ligation or bilateral nephrectomy.", "content": "The structural response of the parathyroid glands to ureteral ligation or bilateral nephrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003317"}
{"pmid": "21003318", "title": "Tensile strength of tissues as influenced by male sex hormone.", "content": "Tensile strength of tissues as influenced by male sex hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003318"}
{"pmid": "21003319", "title": "The functional significance of the declination of the axis of the subtalar joint.", "content": "The functional significance of the declination of the axis of the subtalar joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003319"}
{"pmid": "21003320", "title": "The normal stages in the development of the South African clawed toad, Xenopus laevis.", "content": "The normal stages in the development of the South African clawed toad, Xenopus laevis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003320"}
{"pmid": "21003321", "title": "The effects of lactogenic hormone on post parturient unsuckled mammary glands of the mouse.", "content": "The effects of lactogenic hormone on post parturient unsuckled mammary glands of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003321"}
{"pmid": "21003322", "title": "The influence of the eyes on the melanophores in amphibians.", "content": "The influence of the eyes on the melanophores in amphibians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003322"}
{"pmid": "21003323", "title": "Disappearance of nerve cells after concussion.", "content": "Disappearance of nerve cells after concussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003323"}
{"pmid": "21003324", "title": "A rapid field method for assessing the spreading power of anti-malarial oils.", "content": "A rapid field method for assessing the spreading power of anti-malarial oils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003324"}
{"pmid": "21003325", "title": "The residual toxicity of DDT to bed-bugs.", "content": "The residual toxicity of DDT to bed-bugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003325"}
{"pmid": "21003326", "title": "The mosquitoes of Bwamba County, Uganda; the vertical distribution of mosquitoes in a banana plantation and the biting cycle of Aedes (Stegomyia) simpsoni, Theo.", "content": "The mosquitoes of Bwamba County, Uganda; the vertical distribution of mosquitoes in a banana plantation and the biting cycle of Aedes (Stegomyia) simpsoni, Theo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003326"}
{"pmid": "21003328", "title": "Biochemical differences between the solitary and gregarious phases of locusts and noctuids.", "content": "Biochemical differences between the solitary and gregarious phases of locusts and noctuids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003328"}
{"pmid": "21003327", "title": "The use of DDT as a mosquito larvicide on still waters.", "content": "The use of DDT as a mosquito larvicide on still waters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003327"}
{"pmid": "21003331", "title": "Comparative study of the vacuome and of related systems in plants and animals.", "content": "Comparative study of the vacuome and of related systems in plants and animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003331"}
{"pmid": "21003329", "title": "The origin of electricity in the nervous system.", "content": "The origin of electricity in the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003329"}
{"pmid": "21003330", "title": "The existence of a three-generation cycle in several groups of lower plants and animals.", "content": "The existence of a three-generation cycle in several groups of lower plants and animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003330"}
{"pmid": "21003332", "title": "The anaerobic metabolism of invertebrates.", "content": "The anaerobic metabolism of invertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003332"}
{"pmid": "21003381", "title": "Studies on the contractile vacuole of Amoeba dubia.", "content": "Studies on the contractile vacuole of Amoeba dubia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003381"}
{"pmid": "21003382", "title": "Additional data on phenocopies and genic action.", "content": "Additional data on phenocopies and genic action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003382"}
{"pmid": "21003383", "title": "Heteroplastic transplantation of the sinus venosus between 2 species of Amblystoma.", "content": "Heteroplastic transplantation of the sinus venosus between 2 species of Amblystoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003383"}
{"pmid": "21003384", "title": "Return of vision in eyes exchanged between adult salamanders of different species.", "content": "Return of vision in eyes exchanged between adult salamanders of different species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003384"}
{"pmid": "21003385", "title": "Implantation of the rat egg; experimental alteration of uterine polarity.", "content": "Implantation of the rat egg; experimental alteration of uterine polarity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003385"}
{"pmid": "21003386", "title": "Depletions and abnormalities in the cervical sympathetic system of the chick following extirpation of neural crest.", "content": "Depletions and abnormalities in the cervical sympathetic system of the chick following extirpation of neural crest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003386"}
{"pmid": "21003387", "title": "Blastulation, its role in pregastrular organization in Amblystoma punctatum.", "content": "Blastulation, its role in pregastrular organization in Amblystoma punctatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003387"}
{"pmid": "21003388", "title": "Morphogenetic studies of the rabbit; regional specificity of hereditary factors affecting homoeotic variations in the axial skeleton.", "content": "Morphogenetic studies of the rabbit; regional specificity of hereditary factors affecting homoeotic variations in the axial skeleton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003388"}
{"pmid": "21003389", "title": "Functional differentiation in embryonic development; respiration and cytochrome oxidase activity in Amblystoma punctatum.", "content": "Functional differentiation in embryonic development; respiration and cytochrome oxidase activity in Amblystoma punctatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003389"}
{"pmid": "21003390", "title": "Macravestibulum kepneri n. sp.; a morphological and cytological study of a pronocephalid trematode.", "content": "Macravestibulum kepneri n. sp.; a morphological and cytological study of a pronocephalid trematode.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003390"}
{"pmid": "21003391", "title": "The genital vestibule and its significance in the morphology and taxonomy of the Acanthocephala, with particular reference to the genus Corynosoma.", "content": "The genital vestibule and its significance in the morphology and taxonomy of the Acanthocephala, with particular reference to the genus Corynosoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003391"}
{"pmid": "21003392", "title": "The cyclic changes of epithelial cords in the dog ovary.", "content": "The cyclic changes of epithelial cords in the dog ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003392"}
{"pmid": "21003393", "title": "The ovarian cycle of the ring dove Streptopelia risoria.", "content": "The ovarian cycle of the ring dove Streptopelia risoria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003393"}
{"pmid": "21003394", "title": "Studies in carcinogenesis with azo compounds; the action of four azo dyes in mixed and pure strain mice.", "content": "Studies in carcinogenesis with azo compounds; the action of four azo dyes in mixed and pure strain mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003394"}
{"pmid": "21003395", "title": "Studies in carcinogenesis with azo compounds; the action of azo compounds in mice, and the bearing thereof on theories of azo dye carcinogenesis.", "content": "Studies in carcinogenesis with azo compounds; the action of azo compounds in mice, and the bearing thereof on theories of azo dye carcinogenesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003395"}
{"pmid": "21003396", "title": "The deterrent effect of light upon the incidence of spontaneous mammary cancer in mice.", "content": "The deterrent effect of light upon the incidence of spontaneous mammary cancer in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003396"}
{"pmid": "21003397", "title": "The relationship of caloric intake and of blood sugar to sarcogenesis in mice.", "content": "The relationship of caloric intake and of blood sugar to sarcogenesis in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003397"}
{"pmid": "21003398", "title": "Certain effects of dietery pyridoxine and casein on the carcinogenicity of P-dime-thylaminoazobenzene.", "content": "Certain effects of dietery pyridoxine and casein on the carcinogenicity of P-dime-thylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003398"}
{"pmid": "21003399", "title": "Phosphorus compounds in animal tissues; the nucleic acid content of homologous normal and cancer tissues.", "content": "Phosphorus compounds in animal tissues; the nucleic acid content of homologous normal and cancer tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003399"}
{"pmid": "21003400", "title": "Attempts to localize tumor metastases in long bones by mechanical trauma.", "content": "Attempts to localize tumor metastases in long bones by mechanical trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003400"}
{"pmid": "21003401", "title": "Reticuloendothelial immune serum; the effect of strong concentrations on the growth of Walker rat sarcoma 319 in vitro.", "content": "Reticuloendothelial immune serum; the effect of strong concentrations on the growth of Walker rat sarcoma 319 in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003401"}
{"pmid": "21003403", "title": "Peripheral vascular changes in dermatomyositis.", "content": "Peripheral vascular changes in dermatomyositis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003403"}
{"pmid": "21003402", "title": "The syndrome of Bernheim.", "content": "The syndrome of Bernheim.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003402"}
{"pmid": "21003404", "title": "The recruit's heart; reduplication of the first sound; heart strain and a new method of calibration.", "content": "The recruit's heart; reduplication of the first sound; heart strain and a new method of calibration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003404"}
{"pmid": "21003405", "title": "Traumatic injury of the heart; incidence of its occurrence in 42 cases of severe accidental bodily injury.", "content": "Traumatic injury of the heart; incidence of its occurrence in 42 cases of severe accidental bodily injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003405"}
{"pmid": "21003406", "title": "Studies concerning the etiology and pathogenesis of neurocirculatory asthenia; the cardiovascular manifestations of neurocirculatory asthenia.", "content": "Studies concerning the etiology and pathogenesis of neurocirculatory asthenia; the cardiovascular manifestations of neurocirculatory asthenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003406"}
{"pmid": "21003407", "title": "Pulmonary stenosis with intact interventricular septum; report of 11 cases.", "content": "Pulmonary stenosis with intact interventricular septum; report of 11 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003407"}
{"pmid": "21003408", "title": "A note on the serologic classification of streptococci isolated from subacute bacterial endocarditis.", "content": "A note on the serologic classification of streptococci isolated from subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003408"}
{"pmid": "21003409", "title": "Aortic hypoplasia with associated vascular and genitourinary anomalies; report of a case with autopsy.", "content": "Aortic hypoplasia with associated vascular and genitourinary anomalies; report of a case with autopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003409"}
{"pmid": "21003410", "title": "Traumatic rupture of both ventricles of the heart; case report.", "content": "Traumatic rupture of both ventricles of the heart; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003410"}
{"pmid": "21003411", "title": "Isolated myocarditis probably of sulfonamide origin.", "content": "Isolated myocarditis probably of sulfonamide origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003411"}
{"pmid": "21003412", "title": "Myocardial infarction superimposed on short P-R, prolonged QRS complex; a case report.", "content": "Myocardial infarction superimposed on short P-R, prolonged QRS complex; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003412"}
{"pmid": "21003413", "title": "The chemical composition of wheat and rye and of flours derived therefrom.", "content": "The chemical composition of wheat and rye and of flours derived therefrom.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003413"}
{"pmid": "21003415", "title": "Influence of halides on the oxidation of ascorbic acid; action of C1- on the cupric-cuprous system.", "content": "Influence of halides on the oxidation of ascorbic acid; action of C1- on the cupric-cuprous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003415"}
{"pmid": "21003416", "title": "Oxalate content of some leafy green vegetables and its relation to oxaluria and calcium utilization.", "content": "Oxalate content of some leafy green vegetables and its relation to oxaluria and calcium utilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003416"}
{"pmid": "21003418", "title": "A sodium carbonate-bicarbonate buffer for alkaline phosphatases.", "content": "A sodium carbonate-bicarbonate buffer for alkaline phosphatases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003418"}
{"pmid": "21003420", "title": "The non-identity of Thudichum's glycoleucine and norleucine.", "content": "The non-identity of Thudichum's glycoleucine and norleucine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003420"}
{"pmid": "21003422", "title": "The thermal destruction of vitamin B1; the influence of buffer salts on the rate of destruction of co-carboxylase at 100 degrees C.", "content": "The thermal destruction of vitamin B1; the influence of buffer salts on the rate of destruction of co-carboxylase at 100 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003422"}
{"pmid": "21003426", "title": "Biochemical characterization of the actions of chemotherapeutic agents; time-relationships between metabolic and growth inhibitions by pantoyltaurine.", "content": "Biochemical characterization of the actions of chemotherapeutic agents; time-relationships between metabolic and growth inhibitions by pantoyltaurine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003426"}
{"pmid": "21003427", "title": "The effect of various solvents on the rate of elimination and carcinogenic activity of 3;4-benzypyrene.", "content": "The effect of various solvents on the rate of elimination and carcinogenic activity of 3;4-benzypyrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003427"}
{"pmid": "21003428", "title": "The metabolism of sulphanilamide; metanilamide and orthanilamide.", "content": "The metabolism of sulphanilamide; metanilamide and orthanilamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003428"}
{"pmid": "21003429", "title": "Enzymic and antigenic responses of Esch. coli to growth in glucose-containing media.", "content": "Enzymic and antigenic responses of Esch. coli to growth in glucose-containing media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003429"}
{"pmid": "21003430", "title": "The effect of pH on the solubility of sulphonamides.", "content": "The effect of pH on the solubility of sulphonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003430"}
{"pmid": "21003454", "title": "Evolution of orthodontic theory and practice.", "content": "Evolution of orthodontic theory and practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003454"}
{"pmid": "21003455", "title": "Focal infection.", "content": "Focal infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003455"}
{"pmid": "21003456", "title": "Factors in the etiology of wastings.", "content": "Factors in the etiology of wastings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003456"}
{"pmid": "21003457", "title": "The evaluation of the different types of treatment for some periodontal disturbances.", "content": "The evaluation of the different types of treatment for some periodontal disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003457"}
{"pmid": "21003458", "title": "A case of multiple exostoses of the mandible and sclerosis of the facial bones.", "content": "A case of multiple exostoses of the mandible and sclerosis of the facial bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003458"}
{"pmid": "21003460", "title": "Wetting agents in metal casting processes.", "content": "Wetting agents in metal casting processes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003460"}
{"pmid": "21003459", "title": "Regional anaesthesia of the maxillary nerve by the palatal method.", "content": "Regional anaesthesia of the maxillary nerve by the palatal method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003459"}
{"pmid": "21003461", "title": "A note on dry socket.", "content": "A note on dry socket.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003461"}
{"pmid": "21003462", "title": "Notes on prosthetic procedures.", "content": "Notes on prosthetic procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003462"}
{"pmid": "21003463", "title": "Traumatic oedema of larynx.", "content": "Traumatic oedema of larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003463"}
{"pmid": "21003464", "title": "The importance of the over-jet in full denture construction.", "content": "The importance of the over-jet in full denture construction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003464"}
{"pmid": "21003465", "title": "A modification of the pinledge inlay technique.", "content": "A modification of the pinledge inlay technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003465"}
{"pmid": "21003466", "title": "A new retractor for oral surgical procedures.", "content": "A new retractor for oral surgical procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003466"}
{"pmid": "21003467", "title": "Restoration of the plane of occlusion and the vertical dimension.", "content": "Restoration of the plane of occlusion and the vertical dimension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003467"}
{"pmid": "21003468", "title": "Partial denture prosthesis (resiliency in articulation).", "content": "Partial denture prosthesis (resiliency in articulation).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003468"}
{"pmid": "21003469", "title": "Extra-oral retention splints.", "content": "Extra-oral retention splints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003469"}
{"pmid": "21003470", "title": "Surgical treatment of oral lesions resulting from prostheses.", "content": "Surgical treatment of oral lesions resulting from prostheses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003470"}
{"pmid": "21003472", "title": "Some cases from practice.", "content": "Some cases from practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003472"}
{"pmid": "21003471", "title": "Plastic facial restorations.", "content": "Plastic facial restorations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003471"}
{"pmid": "21003473", "title": "A possibility for physiologic orthodontic movement.", "content": "A possibility for physiologic orthodontic movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003473"}
{"pmid": "21003477", "title": "A study of plate waste as a directive measure in food conservation.", "content": "A study of plate waste as a directive measure in food conservation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003477"}
{"pmid": "21003478", "title": "Some pictures of food consumption in the United States, 1860-1941.", "content": "Some pictures of food consumption in the United States, 1860-1941.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003478"}
{"pmid": "21003480", "title": "Soybeans and soybean products in the menu.", "content": "Soybeans and soybean products in the menu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003480"}
{"pmid": "21003479", "title": "Effect of freezing preservation and cooking on vitamin content of green soybeans and soybean sprouts.", "content": "Effect of freezing preservation and cooking on vitamin content of green soybeans and soybean sprouts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003479"}
{"pmid": "21003481", "title": "Effect of quantity preparation procedures on vitamin retention; canned peas.", "content": "Effect of quantity preparation procedures on vitamin retention; canned peas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003481"}
{"pmid": "21003482", "title": "The biochemical effects of injections of sex hormones into castrated rats.", "content": "The biochemical effects of injections of sex hormones into castrated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003482"}
{"pmid": "21003483", "title": "Optimal mating time for pregnancy in the monkey.", "content": "Optimal mating time for pregnancy in the monkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003483"}
{"pmid": "21003484", "title": "Glucose tolerance in rats following repeated small doses of alloxan.", "content": "Glucose tolerance in rats following repeated small doses of alloxan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003484"}
{"pmid": "21003485", "title": "Metabolism of the steroid hormones; the isolation of Delta 5-androstenediol-3 (beta), 17 (alpha) and Delta 5-pregnenediol-3 (beta), 20 (alpha).", "content": "Metabolism of the steroid hormones; the isolation of Delta 5-androstenediol-3 (beta), 17 (alpha) and Delta 5-pregnenediol-3 (beta), 20 (alpha).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003485"}
{"pmid": "21003486", "title": "Endocrine function of the spleen and its participation in the pituitary-adrenal response to stress.", "content": "Endocrine function of the spleen and its participation in the pituitary-adrenal response to stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003486"}
{"pmid": "21003487", "title": "A comparison of adrenal steroid diabetes and pancreatic diabetes in the rat.", "content": "A comparison of adrenal steroid diabetes and pancreatic diabetes in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003487"}
{"pmid": "21003488", "title": "Induction of estrus in the ovariectomized golden hamster.", "content": "Induction of estrus in the ovariectomized golden hamster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003488"}
{"pmid": "21003490", "title": "Activity of synthetic estrogens on oral administration in the domestic fowl and turkey.", "content": "Activity of synthetic estrogens on oral administration in the domestic fowl and turkey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003490"}
{"pmid": "21003491", "title": "The effect of insulin on the survival times of eviscerated rats.", "content": "The effect of insulin on the survival times of eviscerated rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003491"}
{"pmid": "21003489", "title": "The influence of goitrogenic compounds (sulfonamides and their derivatives, thiourea and its derivatives) on respiration of thyroid tissue.", "content": "The influence of goitrogenic compounds (sulfonamides and their derivatives, thiourea and its derivatives) on respiration of thyroid tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003489"}
{"pmid": "21003492", "title": "Testosterone propionate induces secretion of mammary glands of suckling female rats.", "content": "Testosterone propionate induces secretion of mammary glands of suckling female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003492"}
{"pmid": "21003493", "title": "The effect of feeding thiouracil to hens upon the thyroid gland of chicks.", "content": "The effect of feeding thiouracil to hens upon the thyroid gland of chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003493"}
{"pmid": "21003474", "title": "Space maintainers.", "content": "Space maintainers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003474"}
{"pmid": "21003495", "title": "Analysis of a mutator.", "content": "Analysis of a mutator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003495"}
{"pmid": "21003498", "title": "Heterosis resulting from degenerative changes.", "content": "Heterosis resulting from degenerative changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003498"}
{"pmid": "21003496", "title": "Evidence of genes for female sterility in dairy cows.", "content": "Evidence of genes for female sterility in dairy cows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003496"}
{"pmid": "21003494", "title": "Evidence for normal segregation of species-specific antigens in the backcross of species hybrids in doves.", "content": "Evidence for normal segregation of species-specific antigens in the backcross of species hybrids in doves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003494"}
{"pmid": "21003499", "title": "A case of neighboring loci with similar effects.", "content": "A case of neighboring loci with similar effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003499"}
{"pmid": "21003497", "title": "Location of the centromeres on the linkage maps of maize.", "content": "Location of the centromeres on the linkage maps of maize.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003497"}
{"pmid": "21003500", "title": "The behaviour of the foetus in utero with special reference to the incidence of breech presentation at term.", "content": "The behaviour of the foetus in utero with special reference to the incidence of breech presentation at term.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003500"}
{"pmid": "21003501", "title": "Body temperature; a diagnostic aid in menstrual disorders and sterility.", "content": "Body temperature; a diagnostic aid in menstrual disorders and sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003501"}
{"pmid": "21003475", "title": "Management of the child patient.", "content": "Management of the child patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003475"}
{"pmid": "21003502", "title": "The association of erythroblastosis foetalis and accidental antepartum haemorrhage.", "content": "The association of erythroblastosis foetalis and accidental antepartum haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003502"}
{"pmid": "21003476", "title": "Pulp management in deciduous teeth.", "content": "Pulp management in deciduous teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003476"}
{"pmid": "21003503", "title": "A morphological study on chorioepithelial proliferations.", "content": "A morphological study on chorioepithelial proliferations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003503"}
{"pmid": "21003504", "title": "The effect of postoperative exercises and massage on the incidence of pulmonary embolism at Chelsea Hospital for Women.", "content": "The effect of postoperative exercises and massage on the incidence of pulmonary embolism at Chelsea Hospital for Women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003504"}
{"pmid": "21003505", "title": "A short study of histaminase activity during pregnancy.", "content": "A short study of histaminase activity during pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003505"}
{"pmid": "21003506", "title": "Acute hydramnios; a brief survey of the recent literature, with report of a case simulating concealed accidental haemorrhage.", "content": "Acute hydramnios; a brief survey of the recent literature, with report of a case simulating concealed accidental haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003506"}
{"pmid": "21003507", "title": "Treatment with penicillin of some obstetric cases.", "content": "Treatment with penicillin of some obstetric cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003507"}
{"pmid": "21003508", "title": "A case of Meigs's syndrome.", "content": "A case of Meigs's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003508"}
{"pmid": "21003509", "title": "Carcinoma of the female urethra; review of the literature and report of 3 cases.", "content": "Carcinoma of the female urethra; review of the literature and report of 3 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003509"}
{"pmid": "21003510", "title": "Fused twin monster.", "content": "Fused twin monster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003510"}
{"pmid": "21003511", "title": "A case of sympus dipus.", "content": "A case of sympus dipus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003511"}
{"pmid": "21003512", "title": "Tuberculosis and genius; Ralph Waldo Emerson.", "content": "Tuberculosis and genius; Ralph Waldo Emerson.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003512"}
{"pmid": "21003513", "title": "Hippocratic writings in the Middle Ages.", "content": "Hippocratic writings in the Middle Ages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003513"}
{"pmid": "21003514", "title": "The Hebrew-Aramaic element in Vesalius' Tabulae anatomicae sex, a critical analysis.", "content": "The Hebrew-Aramaic element in Vesalius' Tabulae anatomicae sex, a critical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003514"}
{"pmid": "21003515", "title": "Medical consultation on the case of Daniel Vanslyke.", "content": "Medical consultation on the case of Daniel Vanslyke.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003515"}
{"pmid": "21003516", "title": "A note on the centenary of John Goodsir's Anatomical and Pathological Observations.", "content": "A note on the centenary of John Goodsir's Anatomical and Pathological Observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003516"}
{"pmid": "21003517", "title": "Notes on Dr. John Morgan and his relations with Italian men and women of science.", "content": "Notes on Dr. John Morgan and his relations with Italian men and women of science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003517"}
{"pmid": "21003518", "title": "History of science in Sweden.", "content": "History of science in Sweden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003518"}
{"pmid": "21003519", "title": "The Wright Field libraries at Dayton, Ohio.", "content": "The Wright Field libraries at Dayton, Ohio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003519"}
{"pmid": "21003520", "title": "The Aero Medical Library.", "content": "The Aero Medical Library.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003520"}
{"pmid": "21003521", "title": "Tinea unguis (onychomycosis, ringworm of the nail).", "content": "Tinea unguis (onychomycosis, ringworm of the nail).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003521"}
{"pmid": "21003522", "title": "Therapy for pronated feet in childhood.", "content": "Therapy for pronated feet in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003522"}
{"pmid": "21003523", "title": "Pruritus ani.", "content": "Pruritus ani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003523"}
{"pmid": "21003524", "title": "Painless proctology.", "content": "Painless proctology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003524"}
{"pmid": "21003525", "title": "Non-specific colitis.", "content": "Non-specific colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003525"}
{"pmid": "21003526", "title": "Group medicine; social significance.", "content": "Group medicine; social significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003526"}
{"pmid": "21003527", "title": "War secrets that saved lives.", "content": "War secrets that saved lives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003527"}
{"pmid": "21003528", "title": "Hospital treatment of psychiatric patients.", "content": "Hospital treatment of psychiatric patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003528"}
{"pmid": "21003529", "title": "Medical records.", "content": "Medical records.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003529"}
{"pmid": "21003530", "title": "The nurse; link between patient and doctor.", "content": "The nurse; link between patient and doctor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003530"}
{"pmid": "21003531", "title": "Iron and anemia.", "content": "Iron and anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003531"}
{"pmid": "21003532", "title": "Integrating of nursing and hospital facilities.", "content": "Integrating of nursing and hospital facilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003532"}
{"pmid": "21003534", "title": "Spontaneous loss of specificity of absorbed immune hemagglutinating sera.", "content": "Spontaneous loss of specificity of absorbed immune hemagglutinating sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003534"}
{"pmid": "21003535", "title": "The standardization of the cardiolipin-lecithin-cholesterol antigen in the complement fixation test for syphilis.", "content": "The standardization of the cardiolipin-lecithin-cholesterol antigen in the complement fixation test for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003535"}
{"pmid": "21003536", "title": "Studies on the A-antigenic polysaccharide from the abomasus of cattle.", "content": "Studies on the A-antigenic polysaccharide from the abomasus of cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003536"}
{"pmid": "21003537", "title": "On the inhomogeneity of the urinary human A-substance.", "content": "On the inhomogeneity of the urinary human A-substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003537"}
{"pmid": "21003538", "title": "Distribution of the blood-groups, subgroups, and Rh blood-types in Japanese.", "content": "Distribution of the blood-groups, subgroups, and Rh blood-types in Japanese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003538"}
{"pmid": "21003539", "title": "Immunological studies on scorpions.", "content": "Immunological studies on scorpions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003539"}
{"pmid": "21003540", "title": "Methods for the production of the alpha and theta toxins of Clostridium welchii.", "content": "Methods for the production of the alpha and theta toxins of Clostridium welchii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003540"}
{"pmid": "21003541", "title": "Antigens of Shigella sonnei.", "content": "Antigens of Shigella sonnei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003541"}
{"pmid": "21003542", "title": "p-Aminobenzoic acid synthesis by Neisseria gonorrhoeae in relation to clinical and cultural sulfonamide resistance.", "content": "p-Aminobenzoic acid synthesis by Neisseria gonorrhoeae in relation to clinical and cultural sulfonamide resistance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003542"}
{"pmid": "21003543", "title": "A specific antigen recovered from tissue infected with M. paratuberculosis (Johne's bacillus).", "content": "A specific antigen recovered from tissue infected with M. paratuberculosis (Johne's bacillus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003543"}
{"pmid": "21003544", "title": "The effect of environmental temperature on experimental influenza in mice.", "content": "The effect of environmental temperature on experimental influenza in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003544"}
{"pmid": "21003545", "title": "The type-specificity of immune protection against Shigella paradysenteriae (Flexner).", "content": "The type-specificity of immune protection against Shigella paradysenteriae (Flexner).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003545"}
{"pmid": "21003546", "title": "The relation between illumination and vision.", "content": "The relation between illumination and vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003546"}
{"pmid": "21003547", "title": "New procedure to measure accurately illumination, at large angles of incidence, with a barrier-layer cell.", "content": "New procedure to measure accurately illumination, at large angles of incidence, with a barrier-layer cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003547"}
{"pmid": "21003548", "title": "The relation of hypersensitiveness to poison ivy and to the pure ingredients in cashew nut shell liquid and related substances.", "content": "The relation of hypersensitiveness to poison ivy and to the pure ingredients in cashew nut shell liquid and related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003548"}
{"pmid": "21003549", "title": "Physical medicine in industrial injuries.", "content": "Physical medicine in industrial injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003549"}
{"pmid": "21003550", "title": "The consultant in relation to the plant physician.", "content": "The consultant in relation to the plant physician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003550"}
{"pmid": "21003551", "title": "The thymol-barbitone test in clinical practice.", "content": "The thymol-barbitone test in clinical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003551"}
{"pmid": "21003552", "title": "Illness in industry.", "content": "Illness in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003552"}
{"pmid": "21003553", "title": "Army industrial medical program at a port of embarkation.", "content": "Army industrial medical program at a port of embarkation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003553"}
{"pmid": "21003554", "title": "Health aspects of aluminum ponton work.", "content": "Health aspects of aluminum ponton work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003554"}
{"pmid": "21003555", "title": "Establishing an industrial psychiatric program.", "content": "Establishing an industrial psychiatric program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003555"}
{"pmid": "21003556", "title": "The war's impact and influence on industrial medicine.", "content": "The war's impact and influence on industrial medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003556"}
{"pmid": "21003557", "title": "Social service and the Selective Service medical survey program.", "content": "Social service and the Selective Service medical survey program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003557"}
{"pmid": "21003558", "title": "OLD AGE assistance in Minnesota; physical condition of OAA recipients.", "content": "OLD AGE assistance in Minnesota; physical condition of OAA recipients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003558"}
{"pmid": "21003566", "title": "The skin carcinoma of xeroderma pigmentosum, seamen's skin, and x-ray dermatitis.", "content": "The skin carcinoma of xeroderma pigmentosum, seamen's skin, and x-ray dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003566"}
{"pmid": "21003567", "title": "Thyrotoxicosis with exophthalmos in the rabbit produced by stimulation of the anterior hypophysis with oestrogenic hormone.", "content": "Thyrotoxicosis with exophthalmos in the rabbit produced by stimulation of the anterior hypophysis with oestrogenic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003567"}
{"pmid": "21003559", "title": "Irradiation effects on genetic resistance of mice to mouse typhoid.", "content": "Irradiation effects on genetic resistance of mice to mouse typhoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003559"}
{"pmid": "21003568", "title": "A study in the toxicology of emetine.", "content": "A study in the toxicology of emetine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003568"}
{"pmid": "21003570", "title": "The incubation period in experimental cutaneous leishmaniasis.", "content": "The incubation period in experimental cutaneous leishmaniasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003570"}
{"pmid": "21003569", "title": "The malignant phase of hypertension.", "content": "The malignant phase of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003569"}
{"pmid": "21003571", "title": "Sympathetic surgery in ophthalmology.", "content": "Sympathetic surgery in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003571"}
{"pmid": "21003564", "title": "Toxoplasmosis in the monkey; acute fatal infection experimentally produced in a young Macaca mulatta.", "content": "Toxoplasmosis in the monkey; acute fatal infection experimentally produced in a young Macaca mulatta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003564"}
{"pmid": "21003560", "title": "Common antigens among filarial and other nematode parasites of man.", "content": "Common antigens among filarial and other nematode parasites of man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003560"}
{"pmid": "21003572", "title": "The operative treatment of stricture of the anus.", "content": "The operative treatment of stricture of the anus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003572"}
{"pmid": "21003561", "title": "The problem of the dangerous carrier of hemolytic streptococci; spread of infection by individuals with strongly positive nose cultures who expelled large numbers of hemolytic streptococci.", "content": "The problem of the dangerous carrier of hemolytic streptococci; spread of infection by individuals with strongly positive nose cultures who expelled large numbers of hemolytic streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003561"}
{"pmid": "21003565", "title": "Increased parasitemia in chicken malaria (Plasmodium gallinaceum and Plasmodium lophurae) following x-irradiation.", "content": "Increased parasitemia in chicken malaria (Plasmodium gallinaceum and Plasmodium lophurae) following x-irradiation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003565"}
{"pmid": "21003573", "title": "Typhoid bacilli in spinal fluid.", "content": "Typhoid bacilli in spinal fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003573"}
{"pmid": "21003574", "title": "A case of cardiac aneurysm.", "content": "A case of cardiac aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003574"}
{"pmid": "21003575", "title": "A case of leukaemoid myeloid reaction in a girl aged 9 months.", "content": "A case of leukaemoid myeloid reaction in a girl aged 9 months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003575"}
{"pmid": "21003576", "title": "A new clinical sign in cholelithiasis.", "content": "A new clinical sign in cholelithiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003576"}
{"pmid": "21003562", "title": "Inflammatory reactions in the skin of normal and immune canaries and monkeys after the local injection of malarial blood.", "content": "Inflammatory reactions in the skin of normal and immune canaries and monkeys after the local injection of malarial blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003562"}
{"pmid": "21003563", "title": "The determination of antitrypanosome effect of antimonials in vitro.", "content": "The determination of antitrypanosome effect of antimonials in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003563"}
{"pmid": "21003577", "title": "Observations on the capillaries of the nailfold in psychoneurotic patients.", "content": "Observations on the capillaries of the nailfold in psychoneurotic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003577"}
{"pmid": "21003579", "title": "Cryptorchidism.", "content": "Cryptorchidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003579"}
{"pmid": "21003578", "title": "The inverted Gunn phenomenon; a further contribution to the problem of an innervation complex of lid and jaw.", "content": "The inverted Gunn phenomenon; a further contribution to the problem of an innervation complex of lid and jaw.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003578"}
{"pmid": "21003580", "title": "Toxic symptoms due to the use of boric acid.", "content": "Toxic symptoms due to the use of boric acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003580"}
{"pmid": "21003581", "title": "Azotemia in typhus fever.", "content": "Azotemia in typhus fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003581"}
{"pmid": "21003583", "title": "Hyperophthalmopathic Graves' disease.", "content": "Hyperophthalmopathic Graves' disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003583"}
{"pmid": "21003582", "title": "Observations on the treatment of Graves' disease with thiouracil.", "content": "Observations on the treatment of Graves' disease with thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003582"}
{"pmid": "21003584", "title": "The effects of thiouracil on the thyroid gland.", "content": "The effects of thiouracil on the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003584"}
{"pmid": "21003585", "title": "Treatment of postpneumonic thoracic empyema with sulfonamides; penicillin and repeated thoracenteses.", "content": "Treatment of postpneumonic thoracic empyema with sulfonamides; penicillin and repeated thoracenteses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003585"}
{"pmid": "21003586", "title": "The early diagnosis of filariasis and certain suggestions relative to cause of symptoms.", "content": "The early diagnosis of filariasis and certain suggestions relative to cause of symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003586"}
{"pmid": "21003587", "title": "Studies of filariasis in soldiers evacuated from the South Pacific.", "content": "Studies of filariasis in soldiers evacuated from the South Pacific.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003587"}
{"pmid": "21003588", "title": "The unusual in gastrointestinal roentgenology.", "content": "The unusual in gastrointestinal roentgenology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003588"}
{"pmid": "21003589", "title": "Acute infectious polyneuritis (Guillain-Barre type).", "content": "Acute infectious polyneuritis (Guillain-Barre type).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003589"}
{"pmid": "21003590", "title": "Isolated (Fiedler's) myocarditis; report of case first manifested by arterial emboli in extremities and terminally by mural thrombi in three of the heart chambers.", "content": "Isolated (Fiedler's) myocarditis; report of case first manifested by arterial emboli in extremities and terminally by mural thrombi in three of the heart chambers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003590"}
{"pmid": "21003591", "title": "The combination of hyperthyroidism and pernicious anemia; report of a case with a review of the literature.", "content": "The combination of hyperthyroidism and pernicious anemia; report of a case with a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003591"}
{"pmid": "21003592", "title": "Hemolytic anemia, hyperglobulinemia and Boeck's sarcoid.", "content": "Hemolytic anemia, hyperglobulinemia and Boeck's sarcoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003592"}
{"pmid": "21003593", "title": "Post-war medical education.", "content": "Post-war medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003593"}
{"pmid": "21003600", "title": "On military dermatology.", "content": "On military dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003600"}
{"pmid": "21003601", "title": "Self-disinfection of the skin; a short review and some original observations.", "content": "Self-disinfection of the skin; a short review and some original observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003601"}
{"pmid": "21003602", "title": "Mycology of the skin.", "content": "Mycology of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003602"}
{"pmid": "21003603", "title": "The anatomy of cutaneous sensibility.", "content": "The anatomy of cutaneous sensibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003603"}
{"pmid": "21003604", "title": "The skin and the reticular tissue.", "content": "The skin and the reticular tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003604"}
{"pmid": "21003605", "title": "Thermal sweating.", "content": "Thermal sweating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003605"}
{"pmid": "21003606", "title": "Notes on some cutaneous manifestations of dietary deficiency.", "content": "Notes on some cutaneous manifestations of dietary deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003606"}
{"pmid": "21003607", "title": "Scientific principles in the design and choice of ointment bases.", "content": "Scientific principles in the design and choice of ointment bases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003607"}
{"pmid": "21003608", "title": "Psychological factors in cutaneous affections; a note on some recent publications.", "content": "Psychological factors in cutaneous affections; a note on some recent publications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003608"}
{"pmid": "21003609", "title": "A human experiment on the relationship of jaws and syphilis.", "content": "A human experiment on the relationship of jaws and syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003609"}
{"pmid": "21003610", "title": "Therapeutic effect of induced jaundice in rheumatoid arthritis.", "content": "Therapeutic effect of induced jaundice in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003610"}
{"pmid": "21003611", "title": "Acute non-specific mesenteric lymphadenitis.", "content": "Acute non-specific mesenteric lymphadenitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003611"}
{"pmid": "21003612", "title": "The diets of school-children in two industrial towns.", "content": "The diets of school-children in two industrial towns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003612"}
{"pmid": "21003613", "title": "Report on nearthrosis of the shaft of the humerus for amputations round the elbow-joint.", "content": "Report on nearthrosis of the shaft of the humerus for amputations round the elbow-joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003613"}
{"pmid": "21003614", "title": "Agranulocytosis after sulphonamide sensitization; penicillin therapy; death from Ps. pyocyanea septicaemia.", "content": "Agranulocytosis after sulphonamide sensitization; penicillin therapy; death from Ps. pyocyanea septicaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003614"}
{"pmid": "21003615", "title": "Acute yellow necrosis of the liver following trilene anaesthesia.", "content": "Acute yellow necrosis of the liver following trilene anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003615"}
{"pmid": "21003616", "title": "Strangulation of foetal intestine before term.", "content": "Strangulation of foetal intestine before term.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003616"}
{"pmid": "21003617", "title": "An aid to transfusion.", "content": "An aid to transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003617"}
{"pmid": "21003618", "title": "A study of neurosis among repatriated prisoners of war.", "content": "A study of neurosis among repatriated prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003618"}
{"pmid": "21003619", "title": "MEDICAL poets.", "content": "MEDICAL poets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003619"}
{"pmid": "21003620", "title": "DISCOVERY of x-rays.", "content": "DISCOVERY of x-rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003620"}
{"pmid": "21003621", "title": "A psychiatric case treatment at Scarboro Hall.", "content": "A psychiatric case treatment at Scarboro Hall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003621"}
{"pmid": "21003622", "title": "Simple ulcer of caecum.", "content": "Simple ulcer of caecum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003622"}
{"pmid": "21003623", "title": "Topical application of cod liver oil in the treatment of burns.", "content": "Topical application of cod liver oil in the treatment of burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003623"}
{"pmid": "21003624", "title": "The alnico magnet, an aid to bronchoscopy and esophagoscopy.", "content": "The alnico magnet, an aid to bronchoscopy and esophagoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003624"}
{"pmid": "21003625", "title": "A study of a food-borne epidemic of tonsilitis and pharyngitis due to beta-hemolytic streptococcus, type 5.", "content": "A study of a food-borne epidemic of tonsilitis and pharyngitis due to beta-hemolytic streptococcus, type 5.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003625"}
{"pmid": "21003627", "title": "A study of spasticity and paralysis.", "content": "A study of spasticity and paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003627"}
{"pmid": "21003626", "title": "Suppression as an adjunct to the therapy of malaria in non-malaria areas.", "content": "Suppression as an adjunct to the therapy of malaria in non-malaria areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003626"}
{"pmid": "21003628", "title": "Two cases of periarteritis nodosa occurring in the first month of life.", "content": "Two cases of periarteritis nodosa occurring in the first month of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003628"}
{"pmid": "21003629", "title": "Urinary infections, calculi and prostate conditions.", "content": "Urinary infections, calculi and prostate conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003629"}
{"pmid": "21003630", "title": "Diuresis in congestive failure.", "content": "Diuresis in congestive failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003630"}
{"pmid": "21003631", "title": "On the classification of asthma.", "content": "On the classification of asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003631"}
{"pmid": "21003632", "title": "Treatment of the dermatoses by local applications.", "content": "Treatment of the dermatoses by local applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003632"}
{"pmid": "21003633", "title": "Rupture of intervertebral disk or protrusion of nucleus pulposus.", "content": "Rupture of intervertebral disk or protrusion of nucleus pulposus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003633"}
{"pmid": "21003634", "title": "Newer methods of treating late visceral syphilis.", "content": "Newer methods of treating late visceral syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003634"}
{"pmid": "21003635", "title": "The eosinophil count in acute infections.", "content": "The eosinophil count in acute infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003635"}
{"pmid": "21003636", "title": "The evaluation of a new antiseptic solution.", "content": "The evaluation of a new antiseptic solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003636"}
{"pmid": "21003637", "title": "Penicillin aerosol in the management of lobar pneumonia, bronchiectasis, lung abscess, and infective bronchial asthma.", "content": "Penicillin aerosol in the management of lobar pneumonia, bronchiectasis, lung abscess, and infective bronchial asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003637"}
{"pmid": "21003638", "title": "The value of protein and its chemical components (amino acids) in surgical repair.", "content": "The value of protein and its chemical components (amino acids) in surgical repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003638"}
{"pmid": "21003639", "title": "Factors determining the dosage of penicillin in the treatment of infections.", "content": "Factors determining the dosage of penicillin in the treatment of infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003639"}
{"pmid": "21003640", "title": "Shock therapy of psychosis; evidences for and against damage.", "content": "Shock therapy of psychosis; evidences for and against damage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003640"}
{"pmid": "21003641", "title": "Hodgkin's disease and allied conditions.", "content": "Hodgkin's disease and allied conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003641"}
{"pmid": "21003642", "title": "The repair of deformities of the hand.", "content": "The repair of deformities of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003642"}
{"pmid": "21003643", "title": "Mandibular fractures.", "content": "Mandibular fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003643"}
{"pmid": "21003644", "title": "Treatment of thermal burns.", "content": "Treatment of thermal burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003644"}
{"pmid": "21003645", "title": "Thiourecil toxicity.", "content": "Thiourecil toxicity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003645"}
{"pmid": "21003646", "title": "Vectors of Tsutsugamushi disease (scrub typhus).", "content": "Vectors of Tsutsugamushi disease (scrub typhus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003646"}
{"pmid": "21003647", "title": "Public health and preventive aspects of streptococcal infections.", "content": "Public health and preventive aspects of streptococcal infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003647"}
{"pmid": "21003648", "title": "Carcinoma of the rectum.", "content": "Carcinoma of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003648"}
{"pmid": "21003649", "title": "Survey of over 13,000 fractures in the employees of the Richmond Shipyards.", "content": "Survey of over 13,000 fractures in the employees of the Richmond Shipyards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003649"}
{"pmid": "21003650", "title": "Cardiac pathology as related to anesthesia.", "content": "Cardiac pathology as related to anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003650"}
{"pmid": "21003651", "title": "Filariasis.", "content": "Filariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003651"}
{"pmid": "21003652", "title": "Atelectasis of the newborn.", "content": "Atelectasis of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003652"}
{"pmid": "21003653", "title": "Staphylococcus aureus endocarditis; treatment with penicillin; report of a case.", "content": "Staphylococcus aureus endocarditis; treatment with penicillin; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003653"}
{"pmid": "21003654", "title": "Blood transfusions at the San Francisco Hospital.", "content": "Blood transfusions at the San Francisco Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003654"}
{"pmid": "21003655", "title": "The human requirements of thiamine.", "content": "The human requirements of thiamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003655"}
{"pmid": "21003656", "title": "Air-borne fungus spores in Manitoba (a six-year survey, 1939-1944).", "content": "Air-borne fungus spores in Manitoba (a six-year survey, 1939-1944).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003656"}
{"pmid": "21003657", "title": "Psychiatry in industry.", "content": "Psychiatry in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003657"}
{"pmid": "21003659", "title": "Indications for and end results of the fenestration operation.", "content": "Indications for and end results of the fenestration operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003659"}
{"pmid": "21003658", "title": "Medical care in the coal mining and steel industries of Nova Scotia.", "content": "Medical care in the coal mining and steel industries of Nova Scotia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003658"}
{"pmid": "21003660", "title": "Corneal transplantation.", "content": "Corneal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003660"}
{"pmid": "21003661", "title": "A case of funnel chest.", "content": "A case of funnel chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003661"}
{"pmid": "21003662", "title": "A source of danger in thoracentesis and its prevention.", "content": "A source of danger in thoracentesis and its prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003662"}
{"pmid": "21003663", "title": "Anaemias of the new-born.", "content": "Anaemias of the new-born.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003663"}
{"pmid": "21003664", "title": "An epidemic of acute laryngotracheo-bronchitis.", "content": "An epidemic of acute laryngotracheo-bronchitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003664"}
{"pmid": "21003665", "title": "Nasal medication in sinusitis.", "content": "Nasal medication in sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003665"}
{"pmid": "21003666", "title": "Three problems of the amputee.", "content": "Three problems of the amputee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003666"}
{"pmid": "21003667", "title": "Tietze's syndrome.", "content": "Tietze's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003667"}
{"pmid": "21003668", "title": "Infective hepatitis.", "content": "Infective hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003668"}
{"pmid": "21003669", "title": "The diagnosis of occupational eczema.", "content": "The diagnosis of occupational eczema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003669"}
{"pmid": "21003670", "title": "The scope of anaesthesiology.", "content": "The scope of anaesthesiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003670"}
{"pmid": "21003671", "title": "Self-inflicted wound of brain with four-inch spike.", "content": "Self-inflicted wound of brain with four-inch spike.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003671"}
{"pmid": "21003672", "title": "Chronic disseminated tuberculosis.", "content": "Chronic disseminated tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003672"}
{"pmid": "21003673", "title": "Caesarean section; report of a case.", "content": "Caesarean section; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003673"}
{"pmid": "21003674", "title": "Nutrition survey of McGill University students.", "content": "Nutrition survey of McGill University students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003674"}
{"pmid": "21003679", "title": "The use of desiccated red blood cells in treatment of ulcers of the skin.", "content": "The use of desiccated red blood cells in treatment of ulcers of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003679"}
{"pmid": "21003680", "title": "Two important post-war problems in neurological surgery.", "content": "Two important post-war problems in neurological surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003680"}
{"pmid": "21003684", "title": "On superficial epitheliomata and chronic arsenical poisoning.", "content": "On superficial epitheliomata and chronic arsenical poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003684"}
{"pmid": "21003708", "title": "An outbreak of enteric fever.", "content": "An outbreak of enteric fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003708"}
{"pmid": "21003707", "title": "Hydatid cysts; a clinical study of a short series.", "content": "Hydatid cysts; a clinical study of a short series.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003707"}
{"pmid": "21003709", "title": "Studies in ringworm; therapy of tinea capitis by gonadotropic hormones.", "content": "Studies in ringworm; therapy of tinea capitis by gonadotropic hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003709"}
{"pmid": "21003710", "title": "The treatment of plague with sulphathiazole.", "content": "The treatment of plague with sulphathiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003710"}
{"pmid": "21003712", "title": "Fatty diarrhoea; a report on 26 cases.", "content": "Fatty diarrhoea; a report on 26 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003712"}
{"pmid": "21003711", "title": "Sulpha drugs in bacillary dysentery.", "content": "Sulpha drugs in bacillary dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003711"}
{"pmid": "21003714", "title": "Pulmonary eosionophilosis.", "content": "Pulmonary eosionophilosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003714"}
{"pmid": "21003713", "title": "Viability of dysentery, enteric and cholera organisms in milk curd (dahi).", "content": "Viability of dysentery, enteric and cholera organisms in milk curd (dahi).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003713"}
{"pmid": "21003715", "title": "Complement-fixation test with Witebsky, Klingenstein, Kuhn or similar antigens; a modified technique.", "content": "Complement-fixation test with Witebsky, Klingenstein, Kuhn or similar antigens; a modified technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003715"}
{"pmid": "21003717", "title": "Glass-blowers' cataract.", "content": "Glass-blowers' cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003717"}
{"pmid": "21003716", "title": "A culture medium from ground-nut meal.", "content": "A culture medium from ground-nut meal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003716"}
{"pmid": "21003718", "title": "Allergic reaction due to malarial infection.", "content": "Allergic reaction due to malarial infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003718"}
{"pmid": "21003719", "title": "The treatment of amoebic dysentery.", "content": "The treatment of amoebic dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003719"}
{"pmid": "21003720", "title": "Cross infection in hospitals.", "content": "Cross infection in hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003720"}
{"pmid": "21003721", "title": "Caesarean section.", "content": "Caesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003721"}
{"pmid": "21003722", "title": "The problem of endemicity of cholera in Bengal; a plea for further investigation.", "content": "The problem of endemicity of cholera in Bengal; a plea for further investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003722"}
{"pmid": "21003723", "title": "New symbols for new ideas.", "content": "New symbols for new ideas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003723"}
{"pmid": "21003724", "title": "The Vi agglutination test and its significance.", "content": "The Vi agglutination test and its significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003724"}
{"pmid": "21003725", "title": "Visceral sensation.", "content": "Visceral sensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003725"}
{"pmid": "21003726", "title": "Biochemistry yesterday and tomorrow.", "content": "Biochemistry yesterday and tomorrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003726"}
{"pmid": "21003727", "title": "The aetiology of trachoma in Ireland.", "content": "The aetiology of trachoma in Ireland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003727"}
{"pmid": "21003728", "title": "Lymphangioma of the great omentum.", "content": "Lymphangioma of the great omentum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003728"}
{"pmid": "21003729", "title": "Sulfadiazine resistant strains of beta hemolytic streptococci; appearance during the course of sulfadiazine prophylaxis at a large naval training center.", "content": "Sulfadiazine resistant strains of beta hemolytic streptococci; appearance during the course of sulfadiazine prophylaxis at a large naval training center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003729"}
{"pmid": "21003731", "title": "Use of thiobarbital in the treatment of hyperthyroidism.", "content": "Use of thiobarbital in the treatment of hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003731"}
{"pmid": "21003730", "title": "The development and use of alpha-naphthyl thiourea (ANTU) as a rat poison.", "content": "The development and use of alpha-naphthyl thiourea (ANTU) as a rat poison.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003730"}
{"pmid": "21003733", "title": "Electroencephalographic findings in central nervous system syphilis before and after treatment with penicillin.", "content": "Electroencephalographic findings in central nervous system syphilis before and after treatment with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003733"}
{"pmid": "21003732", "title": "Diagnosis of chancroid; the relative efficiency of biopsies, cultures, smears, autoinoculations and skin tests.", "content": "Diagnosis of chancroid; the relative efficiency of biopsies, cultures, smears, autoinoculations and skin tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003732"}
{"pmid": "21003734", "title": "Intramuscular and subcutaneous administration of penicillin in beeswax-peanut oil.", "content": "Intramuscular and subcutaneous administration of penicillin in beeswax-peanut oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003734"}
{"pmid": "21003735", "title": "Medical care for the American people.", "content": "Medical care for the American people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003735"}
{"pmid": "21003736", "title": "Subcutaneous or extraperitoneal gallbladder (a report of an unusual case).", "content": "Subcutaneous or extraperitoneal gallbladder (a report of an unusual case).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003736"}
{"pmid": "21003737", "title": "PRESIDENT'S National Health Program and the new Wagner bill.", "content": "PRESIDENT'S National Health Program and the new Wagner bill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003737"}
{"pmid": "21003738", "title": "NATIONAL Health Act of 1945.", "content": "NATIONAL Health Act of 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003738"}
{"pmid": "21003739", "title": "SOCIALIZATION of medicine.", "content": "SOCIALIZATION of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003739"}
{"pmid": "21003740", "title": "What is adequate medical care?", "content": "What is adequate medical care?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003740"}
{"pmid": "21003741", "title": "Post-transfusion hepatitis in battle casualties and a study of its prophylaxis by means of human immune serum globulin.", "content": "Post-transfusion hepatitis in battle casualties and a study of its prophylaxis by means of human immune serum globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003741"}
{"pmid": "21003742", "title": "The recognition of primary hyperparathyroidism; an analysis of 24 cases.", "content": "The recognition of primary hyperparathyroidism; an analysis of 24 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003742"}
{"pmid": "21003743", "title": "Relapsing fever; report of a sporadic outbreak, including treatment with penicillin.", "content": "Relapsing fever; report of a sporadic outbreak, including treatment with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003743"}
{"pmid": "21003745", "title": "Peripheral nerve injuries in European theater of operations.", "content": "Peripheral nerve injuries in European theater of operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003745"}
{"pmid": "21003744", "title": "The treatment of lung abscesses with penicillin; report of 4 cases.", "content": "The treatment of lung abscesses with penicillin; report of 4 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003744"}
{"pmid": "21003746", "title": "Pantopaque meningitis disclosed at operation.", "content": "Pantopaque meningitis disclosed at operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003746"}
{"pmid": "21003747", "title": "Neostigmine methylsulfate an apparent specific for arachnidism (black widow spider bite).", "content": "Neostigmine methylsulfate an apparent specific for arachnidism (black widow spider bite).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003747"}
{"pmid": "21003748", "title": "An experiment in teaching freshman medical students.", "content": "An experiment in teaching freshman medical students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003748"}
{"pmid": "21003749", "title": "The teaching of psychopathology.", "content": "The teaching of psychopathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003749"}
{"pmid": "21003750", "title": "Some suggested improvements for postwar medical schools.", "content": "Some suggested improvements for postwar medical schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003750"}
{"pmid": "21003752", "title": "Medical literature and its relation to scientific method.", "content": "Medical literature and its relation to scientific method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003752"}
{"pmid": "21003755", "title": "The effect of hyperthyroidism on diabetes mellitus and carbohydrate metabolism; the role of the liver.", "content": "The effect of hyperthyroidism on diabetes mellitus and carbohydrate metabolism; the role of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003755"}
{"pmid": "21003753", "title": "Effects of the war program on the progress of medical students.", "content": "Effects of the war program on the progress of medical students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003753"}
{"pmid": "21003754", "title": "Chemistry versus tuberculosis; a progress report.", "content": "Chemistry versus tuberculosis; a progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003754"}
{"pmid": "21003751", "title": "The neurological training required by the psychiatrist.", "content": "The neurological training required by the psychiatrist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003751"}
{"pmid": "21003757", "title": "Therapy of chronic diarrhea in adults.", "content": "Therapy of chronic diarrhea in adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003757"}
{"pmid": "21003756", "title": "Rupture of the uterus.", "content": "Rupture of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003756"}
{"pmid": "21003758", "title": "Bilateral cortical necrosis of the kidneys.", "content": "Bilateral cortical necrosis of the kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003758"}
{"pmid": "21003759", "title": "The oral glucose tolerance test.", "content": "The oral glucose tolerance test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003759"}
{"pmid": "21003760", "title": "Biliary cirrhosis of the liver in India with special reference to its treatment.", "content": "Biliary cirrhosis of the liver in India with special reference to its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003760"}
{"pmid": "21003761", "title": "Skin grafting.", "content": "Skin grafting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003761"}
{"pmid": "21003762", "title": "The role of propaganda in the control of leprosy.", "content": "The role of propaganda in the control of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003762"}
{"pmid": "21003763", "title": "The sulphonamide drugs; a short review of their use at the present time.", "content": "The sulphonamide drugs; a short review of their use at the present time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003763"}
{"pmid": "21003764", "title": "Anthiomaline in filariasis.", "content": "Anthiomaline in filariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003764"}
{"pmid": "21003765", "title": "Takata-Ara reaction in the diagnosis of hepatic cirrhosis; further observation on 111 cases.", "content": "Takata-Ara reaction in the diagnosis of hepatic cirrhosis; further observation on 111 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003765"}
{"pmid": "21003766", "title": "Chemical determination of vitamin C sufficiency in India; a comparative study of the different methods.", "content": "Chemical determination of vitamin C sufficiency in India; a comparative study of the different methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003766"}
{"pmid": "21003767", "title": "Observations on renal function in anaemias.", "content": "Observations on renal function in anaemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003767"}
{"pmid": "21003768", "title": "A new sodium antimony gluconate for the treatment of kala-azar.", "content": "A new sodium antimony gluconate for the treatment of kala-azar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003768"}
{"pmid": "21003770", "title": "Whole blood therapy; its past and present.", "content": "Whole blood therapy; its past and present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003770"}
{"pmid": "21003769", "title": "Sulphonamide chemotherapy for intestinal antisepsis.", "content": "Sulphonamide chemotherapy for intestinal antisepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003769"}
{"pmid": "21003772", "title": "Problems of filariasis with reference to post-war planning in India.", "content": "Problems of filariasis with reference to post-war planning in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003772"}
{"pmid": "21003773", "title": "Scabies.", "content": "Scabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003773"}
{"pmid": "21003775", "title": "MEDICAL education in Ireland.", "content": "MEDICAL education in Ireland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003775"}
{"pmid": "21003771", "title": "Tuberculosis; a disease of society.", "content": "Tuberculosis; a disease of society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003771"}
{"pmid": "21003774", "title": "NUTRITIONAL factor in cirrhosis of liver.", "content": "NUTRITIONAL factor in cirrhosis of liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003774"}
{"pmid": "21003776", "title": "The incidence of rickets in Dublin.", "content": "The incidence of rickets in Dublin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003776"}
{"pmid": "21003777", "title": "Medicine and education.", "content": "Medicine and education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003777"}
{"pmid": "21003778", "title": "The primary tuberculosis complex.", "content": "The primary tuberculosis complex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003778"}
{"pmid": "21003779", "title": "Clinical science and methods.", "content": "Clinical science and methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003779"}
{"pmid": "21003825", "title": "Backache.", "content": "Backache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003825"}
{"pmid": "21003826", "title": "Penicillin in the treatment of syphilis.", "content": "Penicillin in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003826"}
{"pmid": "21003827", "title": "The abuse of bed rest in surgery.", "content": "The abuse of bed rest in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003827"}
{"pmid": "21003828", "title": "Pre-sacral nerve resection.", "content": "Pre-sacral nerve resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003828"}
{"pmid": "21003829", "title": "Some examples of vitamin deficiencies seen in Sector 9 hospitals.", "content": "Some examples of vitamin deficiencies seen in Sector 9 hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003829"}
{"pmid": "21003830", "title": "Pitfalls of tropical surgery.", "content": "Pitfalls of tropical surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003830"}
{"pmid": "21003831", "title": "Psychiatric experiences of a general physician in Malta 1941-1943.", "content": "Psychiatric experiences of a general physician in Malta 1941-1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003831"}
{"pmid": "21003832", "title": "Sore nipples; causes and prevention.", "content": "Sore nipples; causes and prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003832"}
{"pmid": "21003833", "title": "Infective hepatitis; transmission by faeces and urine.", "content": "Infective hepatitis; transmission by faeces and urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003833"}
{"pmid": "21003834", "title": "Trichlorethylene as a general anaesthetic in dental surgery; a report based on 2000 cases.", "content": "Trichlorethylene as a general anaesthetic in dental surgery; a report based on 2000 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003834"}
{"pmid": "21003835", "title": "Postscarlatinal encephalitis; report of a case.", "content": "Postscarlatinal encephalitis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003835"}
{"pmid": "21003836", "title": "REST from industry.", "content": "REST from industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003836"}
{"pmid": "21003837", "title": "ADVANCES in disinfestation; DDT.", "content": "ADVANCES in disinfestation; DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003837"}
{"pmid": "21003838", "title": "Gall-stone ileus.", "content": "Gall-stone ileus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003838"}
{"pmid": "21003839", "title": "Tuberculosis in childhood.", "content": "Tuberculosis in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003839"}
{"pmid": "21003840", "title": "Primary tuberculosis in children, causing long illness.", "content": "Primary tuberculosis in children, causing long illness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003840"}
{"pmid": "21003841", "title": "Pre-icteric stage of infective hepatitis; value of biochemical findings in diagnosis.", "content": "Pre-icteric stage of infective hepatitis; value of biochemical findings in diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003841"}
{"pmid": "21003842", "title": "Relapsing fever with nephritis and subarachnoid haemorrhage.", "content": "Relapsing fever with nephritis and subarachnoid haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003842"}
{"pmid": "21003843", "title": "Early treatment of wounds of the knee joint.", "content": "Early treatment of wounds of the knee joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003843"}
{"pmid": "21003844", "title": "Staphylococcal leptoneningitis treated with intracisternal penicillin.", "content": "Staphylococcal leptoneningitis treated with intracisternal penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003844"}
{"pmid": "21003845", "title": "Carbohydrate absorption in sprue.", "content": "Carbohydrate absorption in sprue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003845"}
{"pmid": "21003846", "title": "History of surgical anesthesia.", "content": "History of surgical anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003846"}
{"pmid": "21003847", "title": "The place of orthopaedics in medical education and in the regional hospital service.", "content": "The place of orthopaedics in medical education and in the regional hospital service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003847"}
{"pmid": "21003848", "title": "Trichlorethylene in dental surgery.", "content": "Trichlorethylene in dental surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003848"}
{"pmid": "21003849", "title": "Cultivation of Rickettsia tsutsugamushi in lungs of rodents; preparation of a scrub-typhus vaccine.", "content": "Cultivation of Rickettsia tsutsugamushi in lungs of rodents; preparation of a scrub-typhus vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003849"}
{"pmid": "21003851", "title": "Poisoning by radium carbonate.", "content": "Poisoning by radium carbonate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003851"}
{"pmid": "21003850", "title": "Scrubtyphus vaccine; large-scale production.", "content": "Scrubtyphus vaccine; large-scale production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003850"}
{"pmid": "21003852", "title": "Thiouracil in pregnancy; effect on foetal thyroid.", "content": "Thiouracil in pregnancy; effect on foetal thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003852"}
{"pmid": "21003853", "title": "Direct laryngoscopy and tracheal intubation; a simple method.", "content": "Direct laryngoscopy and tracheal intubation; a simple method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003853"}
{"pmid": "21003854", "title": "Placenta praevia.", "content": "Placenta praevia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003854"}
{"pmid": "21003855", "title": "A new type of enterotome.", "content": "A new type of enterotome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003855"}
{"pmid": "21003856", "title": "Prophylactic use of sulphonamides in rheumatic fever.", "content": "Prophylactic use of sulphonamides in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003856"}
{"pmid": "21003858", "title": "Gynecologic examination; premarital counsel.", "content": "Gynecologic examination; premarital counsel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003858"}
{"pmid": "21003857", "title": "CHILD's death in hospital.", "content": "CHILD's death in hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003857"}
{"pmid": "21003859", "title": "Advances in the treatment of vaginitis.", "content": "Advances in the treatment of vaginitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003859"}
{"pmid": "21003860", "title": "Diseases of the vulva and the problem of sexual dissatisfaction.", "content": "Diseases of the vulva and the problem of sexual dissatisfaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003860"}
{"pmid": "21003861", "title": "Functional menstrual disorders; investigation and endocrine therapy.", "content": "Functional menstrual disorders; investigation and endocrine therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003861"}
{"pmid": "21003862", "title": "Endocrine factors concerned in abnormal and subnormal genital development.", "content": "Endocrine factors concerned in abnormal and subnormal genital development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003862"}
{"pmid": "21003863", "title": "Uses and abuses of endocrine therapy.", "content": "Uses and abuses of endocrine therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003863"}
{"pmid": "21003864", "title": "Dysmenorrhea.", "content": "Dysmenorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003864"}
{"pmid": "21003865", "title": "The menopause.", "content": "The menopause.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003865"}
{"pmid": "21003867", "title": "Toxemias of pregnancy.", "content": "Toxemias of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003867"}
{"pmid": "21003866", "title": "The timing of ovulation by basal temperature graphs.", "content": "The timing of ovulation by basal temperature graphs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003866"}
{"pmid": "21003868", "title": "The management of the pregnant cardiac patient.", "content": "The management of the pregnant cardiac patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003868"}
{"pmid": "21003869", "title": "Pregnancy and tuberculosis.", "content": "Pregnancy and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003869"}
{"pmid": "21003870", "title": "Recent advances in the management of the syphilitic pregnant woman.", "content": "Recent advances in the management of the syphilitic pregnant woman.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003870"}
{"pmid": "21003871", "title": "Pregnancy in diabetes.", "content": "Pregnancy in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003871"}
{"pmid": "21003872", "title": "Puerperal infection, its prevention and treatment.", "content": "Puerperal infection, its prevention and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003872"}
{"pmid": "21003873", "title": "Vaccination during pregnancy as a prophylaxis against puerperal infections.", "content": "Vaccination during pregnancy as a prophylaxis against puerperal infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003873"}
{"pmid": "21003874", "title": "Some psychiatric problems in obstetrics and gynecology; diagnosis and treatment.", "content": "Some psychiatric problems in obstetrics and gynecology; diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003874"}
{"pmid": "21003875", "title": "Management of home deliveries.", "content": "Management of home deliveries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003875"}
{"pmid": "21003876", "title": "Single dose and continuous spinal anesthesia for labor and vaginal delivery.", "content": "Single dose and continuous spinal anesthesia for labor and vaginal delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003876"}
{"pmid": "21003877", "title": "Rh test; vaginal smears for ovarian function and uterine cancer; new tests for pregnancy.", "content": "Rh test; vaginal smears for ovarian function and uterine cancer; new tests for pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003877"}
{"pmid": "21003878", "title": "TREATMENT of infantile paralysis in Australia.", "content": "TREATMENT of infantile paralysis in Australia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003878"}
{"pmid": "21003889", "title": "The value of spa treatment for certain types of war injuries.", "content": "The value of spa treatment for certain types of war injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003889"}
{"pmid": "21003890", "title": "Hearing aids.", "content": "Hearing aids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003890"}
{"pmid": "21003891", "title": "Burns in the Royal Air Force.", "content": "Burns in the Royal Air Force.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003891"}
{"pmid": "21003892", "title": "The protein fractions of blood plasma.", "content": "The protein fractions of blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003892"}
{"pmid": "21003893", "title": "Plastic surgery.", "content": "Plastic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003893"}
{"pmid": "21003895", "title": "The colloidal concept of disease.", "content": "The colloidal concept of disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003895"}
{"pmid": "21003894", "title": "Cutaneous amoebiasis in surgical practice.", "content": "Cutaneous amoebiasis in surgical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003894"}
{"pmid": "21003896", "title": "Orthopaedic surgery in the R.A.F.", "content": "Orthopaedic surgery in the R.A.F.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003896"}
{"pmid": "21003897", "title": "The boundaries of the living.", "content": "The boundaries of the living.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003897"}
{"pmid": "21003898", "title": "The research progress and the common cold.", "content": "The research progress and the common cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003898"}
{"pmid": "21003899", "title": "The management of middle ear disease in younger children.", "content": "The management of middle ear disease in younger children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003899"}
{"pmid": "21003900", "title": "Abdominal tuberculosis.", "content": "Abdominal tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003900"}
{"pmid": "21003901", "title": "The possible dangers of liquid paraffin.", "content": "The possible dangers of liquid paraffin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003901"}
{"pmid": "21003902", "title": "Some observations on rheumatism.", "content": "Some observations on rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003902"}
{"pmid": "21003903", "title": "Malaria in general practice.", "content": "Malaria in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003903"}
{"pmid": "21003904", "title": "The old and infirm in industry.", "content": "The old and infirm in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003904"}
{"pmid": "21003905", "title": "Endocrinopathies in childhood.", "content": "Endocrinopathies in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003905"}
{"pmid": "21003906", "title": "Acute carcinoma.", "content": "Acute carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003906"}
{"pmid": "21003907", "title": "Colles's fracture.", "content": "Colles's fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003907"}
{"pmid": "21003909", "title": "Industrial medicine.", "content": "Industrial medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003909"}
{"pmid": "21003908", "title": "Urinary infections.", "content": "Urinary infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003908"}
{"pmid": "21003910", "title": "Observations on continuous caudal analgesia in obstetrics, based on 202 cases.", "content": "Observations on continuous caudal analgesia in obstetrics, based on 202 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003910"}
{"pmid": "21003911", "title": "Medical treatment of uncomplicated hypertensive vascular disease.", "content": "Medical treatment of uncomplicated hypertensive vascular disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003911"}
{"pmid": "21003912", "title": "Cholecystectomy with an unusual complication; case report.", "content": "Cholecystectomy with an unusual complication; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003912"}
{"pmid": "21003913", "title": "Large multilocular pseudomucinous cystadenoma of the ovary complicating pregnancy; case report.", "content": "Large multilocular pseudomucinous cystadenoma of the ovary complicating pregnancy; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003913"}
{"pmid": "21003914", "title": "Tenonitis complicating mumps.", "content": "Tenonitis complicating mumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003914"}
{"pmid": "21003915", "title": "Chronic suppurative otitis media with fistula of the labyrinth.", "content": "Chronic suppurative otitis media with fistula of the labyrinth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003915"}
{"pmid": "21003916", "title": "Pathologic conditions in the bronchi and the esophagus; a roentgenologic and endoscopic study.", "content": "Pathologic conditions in the bronchi and the esophagus; a roentgenologic and endoscopic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003916"}
{"pmid": "21003917", "title": "Laboratory aids in the early recognition of liver disease.", "content": "Laboratory aids in the early recognition of liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003917"}
{"pmid": "21003918", "title": "Complications of pneumonia.", "content": "Complications of pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003918"}
{"pmid": "21003919", "title": "Total excision of the patella for arthritis of the knee.", "content": "Total excision of the patella for arthritis of the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003919"}
{"pmid": "21003920", "title": "A summary of the neuro-surgical cases treated in a U.S. Army general hospital.", "content": "A summary of the neuro-surgical cases treated in a U.S. Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003920"}
{"pmid": "21003921", "title": "Diagnostic case report.", "content": "Diagnostic case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003921"}
{"pmid": "21003922", "title": "Recent trends in neuropsychiatric thinking and practice.", "content": "Recent trends in neuropsychiatric thinking and practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003922"}
{"pmid": "21003923", "title": "Mental hygiene needs in Nebraska.", "content": "Mental hygiene needs in Nebraska.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003923"}
{"pmid": "21003924", "title": "Thiouracil in the treatment of hyperthyroidism.", "content": "Thiouracil in the treatment of hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003924"}
{"pmid": "21003925", "title": "Malignant lymphoma with meningeal and polyradicular infiltration.", "content": "Malignant lymphoma with meningeal and polyradicular infiltration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003925"}
{"pmid": "21003926", "title": "Penicillin blood levels for 24 hours following a single intramuscular injection of calcium penicillin in beeswax and peanut oil.", "content": "Penicillin blood levels for 24 hours following a single intramuscular injection of calcium penicillin in beeswax and peanut oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003926"}
{"pmid": "21003927", "title": "The treatment of gonococcal urethritis with single injections of penicillin-beeswax-peanut oil mixtures.", "content": "The treatment of gonococcal urethritis with single injections of penicillin-beeswax-peanut oil mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003927"}
{"pmid": "21003928", "title": "Surgical relief for tracheal obstruction from a vascular ring.", "content": "Surgical relief for tracheal obstruction from a vascular ring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003928"}
{"pmid": "21003929", "title": "Death following the intravenous administration of papaverine hydrochloride; a report of 2 cases.", "content": "Death following the intravenous administration of papaverine hydrochloride; a report of 2 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003929"}
{"pmid": "21003930", "title": "Rheumatoid arthritis; its varied clinical manifestations.", "content": "Rheumatoid arthritis; its varied clinical manifestations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003930"}
{"pmid": "21003931", "title": "Radiation pneumonitis; clinicopathological exercises.", "content": "Radiation pneumonitis; clinicopathological exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003931"}
{"pmid": "21003932", "title": "Osteoid osteoma of terminal phalanx of right fifth toe.", "content": "Osteoid osteoma of terminal phalanx of right fifth toe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003932"}
{"pmid": "21003933", "title": "The nutritional status of civilians rescued from Japanese prison camps.", "content": "The nutritional status of civilians rescued from Japanese prison camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003933"}
{"pmid": "21003934", "title": "Therapeutic measures in rheumatic fever; a comparative study of 150 cases.", "content": "Therapeutic measures in rheumatic fever; a comparative study of 150 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003934"}
{"pmid": "21003935", "title": "Coronary-artery disease among physicians.", "content": "Coronary-artery disease among physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003935"}
{"pmid": "21003936", "title": "Surgical emergencies of the alimentary tract of the newborn.", "content": "Surgical emergencies of the alimentary tract of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003936"}
{"pmid": "21003937", "title": "Thrombosis of mesenteric veins.", "content": "Thrombosis of mesenteric veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003937"}
{"pmid": "21003938", "title": "Leiomyoma of terminal ileum.", "content": "Leiomyoma of terminal ileum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003938"}
{"pmid": "21003939", "title": "LIABILITY for malpractice.", "content": "LIABILITY for malpractice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003939"}
{"pmid": "21003940", "title": "The role of sympathectomy in the treatment of immersion foot and frostbite.", "content": "The role of sympathectomy in the treatment of immersion foot and frostbite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003940"}
{"pmid": "21003941", "title": "Penicillin in the treatment of tetanus; report of two cases.", "content": "Penicillin in the treatment of tetanus; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003941"}
{"pmid": "21003942", "title": "Diabetic neuropathy.", "content": "Diabetic neuropathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003942"}
{"pmid": "21003944", "title": "Hemoglobinemia and the hemoglobinurias.", "content": "Hemoglobinemia and the hemoglobinurias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003944"}
{"pmid": "21003943", "title": "Pneumococcal pericarditis treated with intrapericardial penicillin; report of a case.", "content": "Pneumococcal pericarditis treated with intrapericardial penicillin; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003943"}
{"pmid": "21003945", "title": "Oat-cell carcinoma of lung.", "content": "Oat-cell carcinoma of lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003945"}
{"pmid": "21003946", "title": "Embolism of middle cerebral artery, right; cerebral infarction.", "content": "Embolism of middle cerebral artery, right; cerebral infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003946"}
{"pmid": "21003947", "title": "Tropical diseases with special reference to filariasis (Wuchereria bancrofti).", "content": "Tropical diseases with special reference to filariasis (Wuchereria bancrofti).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003947"}
{"pmid": "21003948", "title": "Uremia; diagnostic pitfalls and therapeutic problems.", "content": "Uremia; diagnostic pitfalls and therapeutic problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003948"}
{"pmid": "21003949", "title": "Umbilical changes during pregnancy; a factor in disproving fetal respiration and transmission of fetal heart pulsations to the abdomen.", "content": "Umbilical changes during pregnancy; a factor in disproving fetal respiration and transmission of fetal heart pulsations to the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003949"}
{"pmid": "21003950", "title": "Trends in medical-care insurance in New York State.", "content": "Trends in medical-care insurance in New York State.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003950"}
{"pmid": "21003951", "title": "The role of trauma in acute coronary thrombosis; a clinical study of 200 cases.", "content": "The role of trauma in acute coronary thrombosis; a clinical study of 200 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003951"}
{"pmid": "21003952", "title": "Lead poisoning in a furrier.", "content": "Lead poisoning in a furrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003952"}
{"pmid": "21003953", "title": "Malaria due to Plasmodium falciparum in New York.", "content": "Malaria due to Plasmodium falciparum in New York.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003953"}
{"pmid": "21003954", "title": "Psittacosis as a cause of atypical pneumonia; penicillin therapy.", "content": "Psittacosis as a cause of atypical pneumonia; penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003954"}
{"pmid": "21003955", "title": "Dihydroergotamine in the treatment of migraine; preliminary clinical observations.", "content": "Dihydroergotamine in the treatment of migraine; preliminary clinical observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003955"}
{"pmid": "21003956", "title": "The allergenic effect of silica and its relation to dyspnea in silicosis.", "content": "The allergenic effect of silica and its relation to dyspnea in silicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003956"}
{"pmid": "21003957", "title": "Preliminary report: low-calcium treatment of poliomyelitis.", "content": "Preliminary report: low-calcium treatment of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003957"}
{"pmid": "21003958", "title": "A modification of the syncope syndrome in coramine premedicated blood donors and the relationship of this syndrome to circulatory shock.", "content": "A modification of the syncope syndrome in coramine premedicated blood donors and the relationship of this syndrome to circulatory shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003958"}
{"pmid": "21003959", "title": "Surgical treatment of gastric and duodenal ulcer.", "content": "Surgical treatment of gastric and duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003959"}
{"pmid": "21003960", "title": "Perforation of the sigmoid colon by an ingested toothpick.", "content": "Perforation of the sigmoid colon by an ingested toothpick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003960"}
{"pmid": "21003961", "title": "The immunological aspects of poliomyelitis.", "content": "The immunological aspects of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003961"}
{"pmid": "21003962", "title": "Oral administration of penicillin; with a preliminary report of its clinical application in the treatment of pneumococcic pneumonia.", "content": "Oral administration of penicillin; with a preliminary report of its clinical application in the treatment of pneumococcic pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003962"}
{"pmid": "21003963", "title": "Study of gastric function with the caffeine test meal.", "content": "Study of gastric function with the caffeine test meal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003963"}
{"pmid": "21003965", "title": "Acute suppurative cholangitis; a report of three cases.", "content": "Acute suppurative cholangitis; a report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003965"}
{"pmid": "21003964", "title": "The treatment of alkalosis with intravenous ammonium chloride solution.", "content": "The treatment of alkalosis with intravenous ammonium chloride solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003964"}
{"pmid": "21003966", "title": "Pneumococcal pneumonia, a review of 440 cases.", "content": "Pneumococcal pneumonia, a review of 440 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003966"}
{"pmid": "21003967", "title": "Perforation of the bowel following non-penetrating abdominal trauma.", "content": "Perforation of the bowel following non-penetrating abdominal trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003967"}
{"pmid": "21003969", "title": "Fractures of the spine and pelvis.", "content": "Fractures of the spine and pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003969"}
{"pmid": "21003970", "title": "Closure of colostomies.", "content": "Closure of colostomies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003970"}
{"pmid": "21003968", "title": "The aetiology of essential hypertension.", "content": "The aetiology of essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003968"}
{"pmid": "21003983", "title": "Penicillin.", "content": "Penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003983"}
{"pmid": "21003984", "title": "Caustic strictures of the esophagus.", "content": "Caustic strictures of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003984"}
{"pmid": "21003985", "title": "Omphalocele.", "content": "Omphalocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003985"}
{"pmid": "21003986", "title": "Pneumococcic meningitis.", "content": "Pneumococcic meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003986"}
{"pmid": "21003987", "title": "Recurrent or suppurative parotitis.", "content": "Recurrent or suppurative parotitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003987"}
{"pmid": "21003988", "title": "Posttraumatic ossification of joint capsule.", "content": "Posttraumatic ossification of joint capsule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003988"}
{"pmid": "21003989", "title": "Clinical observations on the use of benadryl; a new antihistamine substance.", "content": "Clinical observations on the use of benadryl; a new antihistamine substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003989"}
{"pmid": "21003990", "title": "Benadryl in the treatment of urticaria.", "content": "Benadryl in the treatment of urticaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003990"}
{"pmid": "21003991", "title": "The symptomatic treatment of bronchial asthma and hay fever with benadryl.", "content": "The symptomatic treatment of bronchial asthma and hay fever with benadryl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003991"}
{"pmid": "21003992", "title": "Use of benadryl in the syndrome of physical allergy of the head; a preliminary report.", "content": "Use of benadryl in the syndrome of physical allergy of the head; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003992"}
{"pmid": "21003993", "title": "The use of benadryl in treating some of the allergic diseases of childhood.", "content": "The use of benadryl in treating some of the allergic diseases of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003993"}
{"pmid": "21003994", "title": "A discussion of benadryl as an antihistamine substance.", "content": "A discussion of benadryl as an antihistamine substance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003994"}
{"pmid": "21003995", "title": "Perforated gastric carcinoma treated by resection; report of case.", "content": "Perforated gastric carcinoma treated by resection; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21003995"}
{"pmid": "21004000", "title": "The hippuric acid excretion test in schizophrenia.", "content": "The hippuric acid excretion test in schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004000"}
{"pmid": "21004001", "title": "Biochemical aspects of anxiety.", "content": "Biochemical aspects of anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004001"}
{"pmid": "21004002", "title": "The relation of some vitamin deficiencies to certain types of mental disorder.", "content": "The relation of some vitamin deficiencies to certain types of mental disorder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004002"}
{"pmid": "21004012", "title": "Influence of induced changes in blood plasma osmotic activity on intestinal absorption.", "content": "Influence of induced changes in blood plasma osmotic activity on intestinal absorption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004012"}
{"pmid": "21004013", "title": "Effect of feeding glucoascorbic acid to white rats, chicks and guinea pigs.", "content": "Effect of feeding glucoascorbic acid to white rats, chicks and guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004013"}
{"pmid": "21004014", "title": "Influence of relaxin on mammary development in sexually immature female rats.", "content": "Influence of relaxin on mammary development in sexually immature female rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004014"}
{"pmid": "21004015", "title": "Heteroplastic lens grafts related to factors inhibiting lens regeneration in Triturus.", "content": "Heteroplastic lens grafts related to factors inhibiting lens regeneration in Triturus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004015"}
{"pmid": "21004016", "title": "A characteristic of human temperature regulation.", "content": "A characteristic of human temperature regulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004016"}
{"pmid": "21004017", "title": "Tolerance curve of vitamin C.", "content": "Tolerance curve of vitamin C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004017"}
{"pmid": "21004018", "title": "Effect of protein depletion on plasma proteins in the dog measured by electrophoretic analysis.", "content": "Effect of protein depletion on plasma proteins in the dog measured by electrophoretic analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004018"}
{"pmid": "21004019", "title": "The antigenicity of Shigella paradysenteriae (Flexner) in saline-in-mineral-oil emulsion.", "content": "The antigenicity of Shigella paradysenteriae (Flexner) in saline-in-mineral-oil emulsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004019"}
{"pmid": "21004020", "title": "Elevation of plasma amino nitrogen as an index of the gravity of hemorrhagic shock.", "content": "Elevation of plasma amino nitrogen as an index of the gravity of hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004020"}
{"pmid": "21004021", "title": "Effect of penicillin on bacterial contamination of eggs and tissue cultures inoculated with unfiltered sputums.", "content": "Effect of penicillin on bacterial contamination of eggs and tissue cultures inoculated with unfiltered sputums.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004021"}
{"pmid": "21004022", "title": "Effects of temperature on the excised frog heart.", "content": "Effects of temperature on the excised frog heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004022"}
{"pmid": "21004023", "title": "Observations on the antigenicity of viridans streptococci isolated from the air.", "content": "Observations on the antigenicity of viridans streptococci isolated from the air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004023"}
{"pmid": "21004024", "title": "Complement fixation antigen in Entamoeba histolytica infection.", "content": "Complement fixation antigen in Entamoeba histolytica infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004024"}
{"pmid": "21004025", "title": "Protection of animals against Cl. welchii (type A) toxin by injection of certain purified lipids.", "content": "Protection of animals against Cl. welchii (type A) toxin by injection of certain purified lipids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004025"}
{"pmid": "21004026", "title": "Influence of dosage and volume on the circulation time.", "content": "Influence of dosage and volume on the circulation time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004026"}
{"pmid": "21004027", "title": "Certain affections of the liver that arise spontaneously in so-called normal stock albino mice.", "content": "Certain affections of the liver that arise spontaneously in so-called normal stock albino mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004027"}
{"pmid": "21004029", "title": "Penicillin resistant staphylococci.", "content": "Penicillin resistant staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004029"}
{"pmid": "21004028", "title": "Effect of rigid sodium restriction on blood pressure and survival of hypertensive rats.", "content": "Effect of rigid sodium restriction on blood pressure and survival of hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004028"}
{"pmid": "21004030", "title": "Relationship between precipitative and protective anti-bodies of type III Shigella paradysenteriae (Flexner) immune serum.", "content": "Relationship between precipitative and protective anti-bodies of type III Shigella paradysenteriae (Flexner) immune serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004030"}
{"pmid": "21004031", "title": "Subtilin, an antibiotic produced by Bacillus subtilis; action on various organisms.", "content": "Subtilin, an antibiotic produced by Bacillus subtilis; action on various organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004031"}
{"pmid": "21004032", "title": "Action of atropine on the turtle heart.", "content": "Action of atropine on the turtle heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004032"}
{"pmid": "21004033", "title": "Response to tissue injury of lymphoid tissue previously altered by castration, thyroidectomy and thyroid feeding.", "content": "Response to tissue injury of lymphoid tissue previously altered by castration, thyroidectomy and thyroid feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004033"}
{"pmid": "21004034", "title": "Studies on the absorption and excretion of streptomycin in animals.", "content": "Studies on the absorption and excretion of streptomycin in animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004034"}
{"pmid": "21004035", "title": "Double lumen catheter for intravenous and intracardiac blood sampling and pressure recording.", "content": "Double lumen catheter for intravenous and intracardiac blood sampling and pressure recording.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004035"}
{"pmid": "21004036", "title": "Simultaneous registration of intrathoracic, right intracardiac and systemic pressure in man.", "content": "Simultaneous registration of intrathoracic, right intracardiac and systemic pressure in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004036"}
{"pmid": "21004037", "title": "Horizontal intracortical organization in the cerebral control of limb movement.", "content": "Horizontal intracortical organization in the cerebral control of limb movement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004037"}
{"pmid": "21004038", "title": "Further report on effect of para-amino-benzoic acid in experimental Tsutsugamushi disease (scrub typhus).", "content": "Further report on effect of para-amino-benzoic acid in experimental Tsutsugamushi disease (scrub typhus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004038"}
{"pmid": "21004039", "title": "Certain bacteriostatic agents added to sera used in diagnostic tests for neurotropic virus infections.", "content": "Certain bacteriostatic agents added to sera used in diagnostic tests for neurotropic virus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004039"}
{"pmid": "21004040", "title": "Propagation of Theiler's GD-VII mouse virus in tissue culture.", "content": "Propagation of Theiler's GD-VII mouse virus in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004040"}
{"pmid": "21004041", "title": "Propagation of rabies virus in tissue culture.", "content": "Propagation of rabies virus in tissue culture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004041"}
{"pmid": "21004042", "title": "Age and autonomic balance.", "content": "Age and autonomic balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004042"}
{"pmid": "21004043", "title": "Effect of glucose injections on fasting ketonemia after low protein diets.", "content": "Effect of glucose injections on fasting ketonemia after low protein diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004043"}
{"pmid": "21004044", "title": "Failure to transmit infectious hepatitis to chimpanzees.", "content": "Failure to transmit infectious hepatitis to chimpanzees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004044"}
{"pmid": "21004045", "title": "Effect of H ion concentration on eluting poliomyelitis virus from cotton fiber.", "content": "Effect of H ion concentration on eluting poliomyelitis virus from cotton fiber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004045"}
{"pmid": "21004046", "title": "Transmission of streptomycin from maternal blood to the fetal circulation and the amniotic fluid.", "content": "Transmission of streptomycin from maternal blood to the fetal circulation and the amniotic fluid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004046"}
{"pmid": "21004047", "title": "Intrasplenic implantation of multiple pellets of estrogenic steroids.", "content": "Intrasplenic implantation of multiple pellets of estrogenic steroids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004047"}
{"pmid": "21004048", "title": "Serologic distinctness of Eastern, Western, and Venezuelan equine encephalomyelitis viruses.", "content": "Serologic distinctness of Eastern, Western, and Venezuelan equine encephalomyelitis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004048"}
{"pmid": "21004049", "title": "Effects of para-aminobenzoic acid in experimental Tsutsugamushi disease (scrub typhus).", "content": "Effects of para-aminobenzoic acid in experimental Tsutsugamushi disease (scrub typhus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004049"}
{"pmid": "21004050", "title": "Experimental hyperplasia of the stomach mucosa.", "content": "Experimental hyperplasia of the stomach mucosa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004050"}
{"pmid": "21004051", "title": "Effect of digitalis on cholinesterase.", "content": "Effect of digitalis on cholinesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004051"}
{"pmid": "21004052", "title": "Exaggerated discharge of neurosomes into spastic muscle by heat reflex.", "content": "Exaggerated discharge of neurosomes into spastic muscle by heat reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004052"}
{"pmid": "21004053", "title": "Studies on mode of action of streptomycin; effect of culture media.", "content": "Studies on mode of action of streptomycin; effect of culture media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004053"}
{"pmid": "21004054", "title": "Studies on antidromic vasodilatation; synaptic connections in the dorsal root ganglion.", "content": "Studies on antidromic vasodilatation; synaptic connections in the dorsal root ganglion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004054"}
{"pmid": "21004055", "title": "Effect of embryo extract on growth of fibroblasts previously irradiated with x-rays.", "content": "Effect of embryo extract on growth of fibroblasts previously irradiated with x-rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004055"}
{"pmid": "21004056", "title": "Effect of temperature on the notion of penicillin in vitro.", "content": "Effect of temperature on the notion of penicillin in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004056"}
{"pmid": "21004057", "title": "Use of beta beta' dithiocyano diethyl ether (RID-O) to control mite infestations in mice.", "content": "Use of beta beta' dithiocyano diethyl ether (RID-O) to control mite infestations in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004057"}
{"pmid": "21004058", "title": "Absence of alteration in the E.E.G. with stilbesterol and progesterone.", "content": "Absence of alteration in the E.E.G. with stilbesterol and progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004058"}
{"pmid": "21004059", "title": "The cephalincholesterol flocculation test in malaria.", "content": "The cephalincholesterol flocculation test in malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004059"}
{"pmid": "21004060", "title": "Further observations on red cell agglutinating agent present in lungs of virus-infected mice.", "content": "Further observations on red cell agglutinating agent present in lungs of virus-infected mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004060"}
{"pmid": "21004061", "title": "Artificial induction of subcutaneous nodules in rheumatic fever.", "content": "Artificial induction of subcutaneous nodules in rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004061"}
{"pmid": "21004063", "title": "Inhibition of cytochrome oxidase (paraphenylendiamine oxidase) of the thyroid gland by thiouracil and other compounds.", "content": "Inhibition of cytochrome oxidase (paraphenylendiamine oxidase) of the thyroid gland by thiouracil and other compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004063"}
{"pmid": "21004062", "title": "Effect of vitamin K deficiency on liver lipids in the chick.", "content": "Effect of vitamin K deficiency on liver lipids in the chick.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004062"}
{"pmid": "21004064", "title": "Antibody response of swine to repeated vaccination with formalin-inactivated, purified swine influenza virus.", "content": "Antibody response of swine to repeated vaccination with formalin-inactivated, purified swine influenza virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004064"}
{"pmid": "21004065", "title": "Absorption of penicillin from the nose and alimentary canal.", "content": "Absorption of penicillin from the nose and alimentary canal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004065"}
{"pmid": "21004066", "title": "Regulatory effect of adrenal cortical extract on elaboration of pituitary adrenotropic hormone.", "content": "Regulatory effect of adrenal cortical extract on elaboration of pituitary adrenotropic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004066"}
{"pmid": "21004067", "title": "Combined anesthesia and hyperimmune serum therapy in the treatment of experimental Western equine encephalomyelitis.", "content": "Combined anesthesia and hyperimmune serum therapy in the treatment of experimental Western equine encephalomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004067"}
{"pmid": "21004068", "title": "Production of extracellular penicillin-inactivating substances associated with penicillin resistance in Staphylococcus aureus.", "content": "Production of extracellular penicillin-inactivating substances associated with penicillin resistance in Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004068"}
{"pmid": "21004070", "title": "Preparation for surgery of patients with colon lesions.", "content": "Preparation for surgery of patients with colon lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004070"}
{"pmid": "21004069", "title": "Adaptability of gonococcus to four bacteriostatic agents, sodium sulfathiazole, rivanol lactate, promin, and penicillin.", "content": "Adaptability of gonococcus to four bacteriostatic agents, sodium sulfathiazole, rivanol lactate, promin, and penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004069"}
{"pmid": "21004071", "title": "Fenestration operation; a clinical study of the permanence of its results.", "content": "Fenestration operation; a clinical study of the permanence of its results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004071"}
{"pmid": "21004072", "title": "Injuries of the hand.", "content": "Injuries of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004072"}
{"pmid": "21004073", "title": "Experimental nephropathies; a summary of experiments on dogs.", "content": "Experimental nephropathies; a summary of experiments on dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004073"}
{"pmid": "21004074", "title": "Ineffectiveness of penicillin in some cases of bacterial endocarditis.", "content": "Ineffectiveness of penicillin in some cases of bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004074"}
{"pmid": "21004075", "title": "Urethrograms of the male urethra.", "content": "Urethrograms of the male urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004075"}
{"pmid": "21004076", "title": "The role of histamine in various pathological conditions and the methods of controlling its effects.", "content": "The role of histamine in various pathological conditions and the methods of controlling its effects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004076"}
{"pmid": "21004077", "title": "The teaching of physical medicine in a medical school.", "content": "The teaching of physical medicine in a medical school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004077"}
{"pmid": "21004106", "title": "The pathology of coronary artery sclerosis and thrombosis.", "content": "The pathology of coronary artery sclerosis and thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004106"}
{"pmid": "21004107", "title": "Recent advances in the treatment of acute myocardial infarction.", "content": "Recent advances in the treatment of acute myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004107"}
{"pmid": "21004108", "title": "The neuro-psychiatric aspects of coronary artery disease.", "content": "The neuro-psychiatric aspects of coronary artery disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004108"}
{"pmid": "21004109", "title": "The clinical aspects of acute coronary thrombosis.", "content": "The clinical aspects of acute coronary thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004109"}
{"pmid": "21004110", "title": "Treatment of Colles' fracture.", "content": "Treatment of Colles' fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004110"}
{"pmid": "21004111", "title": "Nasal hemorrhage in daily practice.", "content": "Nasal hemorrhage in daily practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004111"}
{"pmid": "21004112", "title": "Recovery from cavernous sinus thrombosis and staphylococcic pneumonia by combined use of penicillin, sulfadiazine and antistaphylococcus serum; a case report.", "content": "Recovery from cavernous sinus thrombosis and staphylococcic pneumonia by combined use of penicillin, sulfadiazine and antistaphylococcus serum; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004112"}
{"pmid": "21004113", "title": "Closure of a defect of the skull with tantalum.", "content": "Closure of a defect of the skull with tantalum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004113"}
{"pmid": "21004114", "title": "Lung resection for chronic pulmonary infection.", "content": "Lung resection for chronic pulmonary infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004114"}
{"pmid": "21004115", "title": "Effects of oxygen on auriculoventricular nodal rhythm following acute coronary occlusion.", "content": "Effects of oxygen on auriculoventricular nodal rhythm following acute coronary occlusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004115"}
{"pmid": "21004116", "title": "Office procedure, penicillin treatment for gonorrhea in four hours, male or female.", "content": "Office procedure, penicillin treatment for gonorrhea in four hours, male or female.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004116"}
{"pmid": "21004117", "title": "The Belle Bonfils Memorial Blood Bank.", "content": "The Belle Bonfils Memorial Blood Bank.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004117"}
{"pmid": "21004118", "title": "Vitamin A and porphyrin-like fluorescence in the livers of pellagrins, with special reference to the effects of a high carbohydrate diet and methionine.", "content": "Vitamin A and porphyrin-like fluorescence in the livers of pellagrins, with special reference to the effects of a high carbohydrate diet and methionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004118"}
{"pmid": "21004119", "title": "A survey of vitamins in African foodstuffs; the thiamin content of beans and other legumes.", "content": "A survey of vitamins in African foodstuffs; the thiamin content of beans and other legumes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004119"}
{"pmid": "21004121", "title": "A simple qualitative test for erythrocyte fragility.", "content": "A simple qualitative test for erythrocyte fragility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004121"}
{"pmid": "21004120", "title": "The importance of standardising the oxygen content of the blood in haematocrit determinations.", "content": "The importance of standardising the oxygen content of the blood in haematocrit determinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004120"}
{"pmid": "21004122", "title": "Growth patterns as secondary sex characteristics.", "content": "Growth patterns as secondary sex characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004122"}
{"pmid": "21004124", "title": "Some of the problems of leprosy.", "content": "Some of the problems of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004124"}
{"pmid": "21004123", "title": "The part-time district surgeon in the Transkeian Territories.", "content": "The part-time district surgeon in the Transkeian Territories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004123"}
{"pmid": "21004125", "title": "Transkeian memories.", "content": "Transkeian memories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004125"}
{"pmid": "21004126", "title": "EDUCATIONAL aspects of the national feeding scheme.", "content": "EDUCATIONAL aspects of the national feeding scheme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004126"}
{"pmid": "21004127", "title": "Medicine and radioactive isotopes.", "content": "Medicine and radioactive isotopes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004127"}
{"pmid": "21004128", "title": "Concerning premedical education.", "content": "Concerning premedical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004128"}
{"pmid": "21004147", "title": "Pneumococcal meningitis; a survey of 20 cases.", "content": "Pneumococcal meningitis; a survey of 20 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004147"}
{"pmid": "21004148", "title": "Penicillin and heparin in the treatment of pneumococcal meningitis; case report.", "content": "Penicillin and heparin in the treatment of pneumococcal meningitis; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004148"}
{"pmid": "21004149", "title": "Penicillin therapy for Vincent's ulcers of the tonsils.", "content": "Penicillin therapy for Vincent's ulcers of the tonsils.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004149"}
{"pmid": "21004150", "title": "Further studies on folic acid in the treatment of macrocytic anemia.", "content": "Further studies on folic acid in the treatment of macrocytic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004150"}
{"pmid": "21004151", "title": "Cotton as a suture material.", "content": "Cotton as a suture material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004151"}
{"pmid": "21004152", "title": "Simultaneous ruptured tubal pregnancy and intra-uterine pregnancy with subsequent delivery of a normal infant.", "content": "Simultaneous ruptured tubal pregnancy and intra-uterine pregnancy with subsequent delivery of a normal infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004152"}
{"pmid": "21004153", "title": "The use of sodium vinbarbital in obstetrics.", "content": "The use of sodium vinbarbital in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004153"}
{"pmid": "21004154", "title": "Fat necrosis studies; the effect of soybean and peanut feeding on the blood and urine lipase of rabbits and in the production of fat necrosis.", "content": "Fat necrosis studies; the effect of soybean and peanut feeding on the blood and urine lipase of rabbits and in the production of fat necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004154"}
{"pmid": "21004155", "title": "The psychiatric salvaging of industrial manpower in wartime.", "content": "The psychiatric salvaging of industrial manpower in wartime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004155"}
{"pmid": "21004156", "title": "Oral manifestations and systemic sequences of endodontal and periodontal disease.", "content": "Oral manifestations and systemic sequences of endodontal and periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004156"}
{"pmid": "21004157", "title": "Leptospirosis; report of a case from South Florida.", "content": "Leptospirosis; report of a case from South Florida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004157"}
{"pmid": "21004158", "title": "Waterhouse-Friderichsen syndrome; report of case with recovery.", "content": "Waterhouse-Friderichsen syndrome; report of case with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004158"}
{"pmid": "21004159", "title": "Hereditary deforming chondrodysplasis.", "content": "Hereditary deforming chondrodysplasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004159"}
{"pmid": "21004160", "title": "Report of 2 cases of paresis treated with penicillin.", "content": "Report of 2 cases of paresis treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004160"}
{"pmid": "21004161", "title": "Burns defined or visualized.", "content": "Burns defined or visualized.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004161"}
{"pmid": "21004162", "title": "A critique of the free skin graft.", "content": "A critique of the free skin graft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004162"}
{"pmid": "21004163", "title": "Intervertebral disc lesions; general discussion and consideration of treatment in military service.", "content": "Intervertebral disc lesions; general discussion and consideration of treatment in military service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004163"}
{"pmid": "21004164", "title": "Unusual glandular manifestation of mumps; extra-salivary localization.", "content": "Unusual glandular manifestation of mumps; extra-salivary localization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004164"}
{"pmid": "21004165", "title": "Narcolepsy.", "content": "Narcolepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004165"}
{"pmid": "21004166", "title": "Some endocrinological aspects of testicular tumours.", "content": "Some endocrinological aspects of testicular tumours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004166"}
{"pmid": "21004167", "title": "Romanticism in pathological science.", "content": "Romanticism in pathological science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004167"}
{"pmid": "21004168", "title": "Belsen concentration camp.", "content": "Belsen concentration camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004168"}
{"pmid": "21004169", "title": "DEVICE to improve the care of patients in double hip spica casts.", "content": "DEVICE to improve the care of patients in double hip spica casts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004169"}
{"pmid": "21004171", "title": "AVOIDANCE of trematode infections in the Orient.", "content": "AVOIDANCE of trematode infections in the Orient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004171"}
{"pmid": "21004170", "title": "QUANTITATIVE methods for the evaluation of hookworm infections.", "content": "QUANTITATIVE methods for the evaluation of hookworm infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004170"}
{"pmid": "21004172", "title": "EXERCISE machine for amputations below the knee.", "content": "EXERCISE machine for amputations below the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004172"}
{"pmid": "21004173", "title": "TYPING sera for the genus Shigella.", "content": "TYPING sera for the genus Shigella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004173"}
{"pmid": "21004174", "title": "VIRUS of poliomyelitis.", "content": "VIRUS of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004174"}
{"pmid": "21004175", "title": "USE of DDT in plague control at Casablanca.", "content": "USE of DDT in plague control at Casablanca.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004175"}
{"pmid": "21004176", "title": "NEW spring drop foot brace.", "content": "NEW spring drop foot brace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004176"}
{"pmid": "21004177", "title": "VALUE of anterior-oblique roentgenograms in diagnosis of primary atypical pneumonia.", "content": "VALUE of anterior-oblique roentgenograms in diagnosis of primary atypical pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004177"}
{"pmid": "21004178", "title": "EVALUATION of the untoward reactions attributable to atabrine.", "content": "EVALUATION of the untoward reactions attributable to atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004178"}
{"pmid": "21004179", "title": "MANAGEMENT of hookworm infection.", "content": "MANAGEMENT of hookworm infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004179"}
{"pmid": "21004180", "title": "The treatment of infectious hepatitis by diet and rest.", "content": "The treatment of infectious hepatitis by diet and rest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004180"}
{"pmid": "21004181", "title": "Anesthesia for abdominal surgery following trauma.", "content": "Anesthesia for abdominal surgery following trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004181"}
{"pmid": "21004182", "title": "The successful neurotic soldier.", "content": "The successful neurotic soldier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004182"}
{"pmid": "21004183", "title": "Work furloughs for patients with peripheral nerve injuries.", "content": "Work furloughs for patients with peripheral nerve injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004183"}
{"pmid": "21004184", "title": "The lichen planus-eczematoid dermatitis complex of the Southwest Pacific; a study of 65 cases.", "content": "The lichen planus-eczematoid dermatitis complex of the Southwest Pacific; a study of 65 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004184"}
{"pmid": "21004185", "title": "Reactions to penicillin.", "content": "Reactions to penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004185"}
{"pmid": "21004186", "title": "Mobile medical and dental dispensaries.", "content": "Mobile medical and dental dispensaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004186"}
{"pmid": "21004187", "title": "A mental hygiene unit.", "content": "A mental hygiene unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004187"}
{"pmid": "21004188", "title": "Vitamin C status of troops in the tropics.", "content": "Vitamin C status of troops in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004188"}
{"pmid": "21004189", "title": "The Army Institute of Pathology.", "content": "The Army Institute of Pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004189"}
{"pmid": "21004190", "title": "Skin sensitivity due to atabrine.", "content": "Skin sensitivity due to atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004190"}
{"pmid": "21004191", "title": "Dermatitis from atabrine.", "content": "Dermatitis from atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004191"}
{"pmid": "21004192", "title": "Temporary acrylic ocular prostheses.", "content": "Temporary acrylic ocular prostheses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004192"}
{"pmid": "21004193", "title": "Direct duplication of roentgenograms by artificial solarization.", "content": "Direct duplication of roentgenograms by artificial solarization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004193"}
{"pmid": "21004194", "title": "Simple method of tomography with the standard Army field x-ray unit.", "content": "Simple method of tomography with the standard Army field x-ray unit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004194"}
{"pmid": "21004195", "title": "Useful procedures in the diagnosis of syphilis.", "content": "Useful procedures in the diagnosis of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004195"}
{"pmid": "21004196", "title": "A simple method of air agitation for photoroentgen film washing.", "content": "A simple method of air agitation for photoroentgen film washing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004196"}
{"pmid": "21004197", "title": "Some observations on mumps with special amphasis upon blood and urinary amylase.", "content": "Some observations on mumps with special amphasis upon blood and urinary amylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004197"}
{"pmid": "21004198", "title": "Psychoneurosis and psychopathic states.", "content": "Psychoneurosis and psychopathic states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004198"}
{"pmid": "21004199", "title": "Guide to the laboratory diagnosis of Entamoeba histolytica.", "content": "Guide to the laboratory diagnosis of Entamoeba histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004199"}
{"pmid": "21004200", "title": "Field method for direct estimation of mepacrine in plasma and blood.", "content": "Field method for direct estimation of mepacrine in plasma and blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004200"}
{"pmid": "21004201", "title": "Dupuytren's contracture; a report of 64 cases among the Veterans Guard of Canada.", "content": "Dupuytren's contracture; a report of 64 cases among the Veterans Guard of Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004201"}
{"pmid": "21004202", "title": "Cerebral thrombosis following ligation of internal carotid A-V fistula; treatment with heparin.", "content": "Cerebral thrombosis following ligation of internal carotid A-V fistula; treatment with heparin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004202"}
{"pmid": "21004203", "title": "The treatment of intrathoracic wounds.", "content": "The treatment of intrathoracic wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004203"}
{"pmid": "21004204", "title": "Infectious polyneuritis, diagnostic criteria and military implications; report of 15 cases.", "content": "Infectious polyneuritis, diagnostic criteria and military implications; report of 15 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004204"}
{"pmid": "21004205", "title": "Anaerobic spore-bearing flora of gas gangrene, Italy.", "content": "Anaerobic spore-bearing flora of gas gangrene, Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004205"}
{"pmid": "21004206", "title": "Mobilizing splints in the treatment of motor nerve injuries.", "content": "Mobilizing splints in the treatment of motor nerve injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004206"}
{"pmid": "21004207", "title": "New type of hand dressing to improve function.", "content": "New type of hand dressing to improve function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004207"}
{"pmid": "21004208", "title": "African horse sickness.", "content": "African horse sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004208"}
{"pmid": "21004209", "title": "Vaccination of equines for the prevention of African horse sickness.", "content": "Vaccination of equines for the prevention of African horse sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004209"}
{"pmid": "21004211", "title": "Studies on louse-borne relapsing fever in Tunisia.", "content": "Studies on louse-borne relapsing fever in Tunisia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004211"}
{"pmid": "21004212", "title": "REPORT on cholera studies in Calcutta; value of chemotherapy in the treatment of cholera and use of blood plasma in cholera collapse.", "content": "REPORT on cholera studies in Calcutta; value of chemotherapy in the treatment of cholera and use of blood plasma in cholera collapse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004212"}
{"pmid": "21004213", "title": "Cardiovascular disturbances in Tsutsugamushi disease.", "content": "Cardiovascular disturbances in Tsutsugamushi disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004213"}
{"pmid": "21004214", "title": "Transportation of Japanese prisoners of war.", "content": "Transportation of Japanese prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004214"}
{"pmid": "21004215", "title": "Management of injuries of major blood vessels.", "content": "Management of injuries of major blood vessels.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004215"}
{"pmid": "21004216", "title": "Perinephric abscess; report of 3 cases simulating acute appendicitis.", "content": "Perinephric abscess; report of 3 cases simulating acute appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004216"}
{"pmid": "21004217", "title": "Recurrent indirect hernia.", "content": "Recurrent indirect hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004217"}
{"pmid": "21004218", "title": "Intrabronchial instillation of penicillin or sulfonamide solutions, with bronchial lavage, in treatment of severe bronchiectasis.", "content": "Intrabronchial instillation of penicillin or sulfonamide solutions, with bronchial lavage, in treatment of severe bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004218"}
{"pmid": "21004219", "title": "Anaphylactoid (Sanarelli-Shwartzman) reaction following therapeutic antityphoid injections.", "content": "Anaphylactoid (Sanarelli-Shwartzman) reaction following therapeutic antityphoid injections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004219"}
{"pmid": "21004220", "title": "Roentgen diagnosis of deformities of the cardiac end of the stomach.", "content": "Roentgen diagnosis of deformities of the cardiac end of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004220"}
{"pmid": "21004221", "title": "Occurrence of psychoneurotic symptoms on the various services of a naval hospital.", "content": "Occurrence of psychoneurotic symptoms on the various services of a naval hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004221"}
{"pmid": "21004222", "title": "Disciplinary problems among men with combat fatigue.", "content": "Disciplinary problems among men with combat fatigue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004222"}
{"pmid": "21004223", "title": "Bacteriology of war wounds in the Pacific area.", "content": "Bacteriology of war wounds in the Pacific area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004223"}
{"pmid": "21004224", "title": "Endocrinologic aspects of recruiting.", "content": "Endocrinologic aspects of recruiting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004224"}
{"pmid": "21004225", "title": "Prothrombin liver function test.", "content": "Prothrombin liver function test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004225"}
{"pmid": "21004226", "title": "Allergic reactions to penicillin therapy; report of cases.", "content": "Allergic reactions to penicillin therapy; report of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004226"}
{"pmid": "21004227", "title": "Hypertrophic gingivitis of mouth breathing.", "content": "Hypertrophic gingivitis of mouth breathing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004227"}
{"pmid": "21004228", "title": "Fracture of the zygoma.", "content": "Fracture of the zygoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004228"}
{"pmid": "21004229", "title": "Large infected radicular cyst of mandible; report of a case.", "content": "Large infected radicular cyst of mandible; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004229"}
{"pmid": "21004230", "title": "Case of keratodermia blennorrhagicum (gonorrheal dermatitis).", "content": "Case of keratodermia blennorrhagicum (gonorrheal dermatitis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004230"}
{"pmid": "21004231", "title": "Pylethrombophlebitis and hepatitis following appendectomy; report of a case with recovery.", "content": "Pylethrombophlebitis and hepatitis following appendectomy; report of a case with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004231"}
{"pmid": "21004232", "title": "Universal vascular compressor for the development of collateral blood circulation in arterial and arteriovenous aneurysms.", "content": "Universal vascular compressor for the development of collateral blood circulation in arterial and arteriovenous aneurysms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004232"}
{"pmid": "21004233", "title": "A wire ladder-splint skin-traction device for thigh amputations.", "content": "A wire ladder-splint skin-traction device for thigh amputations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004233"}
{"pmid": "21004234", "title": "Additional operating-room lighting aboard ship.", "content": "Additional operating-room lighting aboard ship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004234"}
{"pmid": "21004236", "title": "Five years of photofluorography in the Navy.", "content": "Five years of photofluorography in the Navy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004236"}
{"pmid": "21004235", "title": "Infection of wild rats on Leyte with Schistoma japonicum.", "content": "Infection of wild rats on Leyte with Schistoma japonicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004235"}
{"pmid": "21004237", "title": "Dysentery epidemic; report of 184 cases.", "content": "Dysentery epidemic; report of 184 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004237"}
{"pmid": "21004239", "title": "Neotypes.", "content": "Neotypes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004239"}
{"pmid": "21004238", "title": "The chalicotheres as a biological type.", "content": "The chalicotheres as a biological type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004238"}
{"pmid": "21004240", "title": "Effect of air temperature on the concentration of certain viruses in cabbage.", "content": "Effect of air temperature on the concentration of certain viruses in cabbage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004240"}
{"pmid": "21004241", "title": "Physiological internal necrosis of potato tubers in Wisconsin.", "content": "Physiological internal necrosis of potato tubers in Wisconsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004241"}
{"pmid": "21004242", "title": "Urinary 17-ketosteroid excretion by boars.", "content": "Urinary 17-ketosteroid excretion by boars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004242"}
{"pmid": "21004243", "title": "Coated lenses for biological photography.", "content": "Coated lenses for biological photography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004243"}
{"pmid": "21004244", "title": "Film slides and movie titles.", "content": "Film slides and movie titles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004244"}
{"pmid": "21004245", "title": "Early photomicrography.", "content": "Early photomicrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004245"}
{"pmid": "21004246", "title": "Half a century of roentgen rays.", "content": "Half a century of roentgen rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004246"}
{"pmid": "21004247", "title": "Circulation in sanitary ventilation by bactericidal irradiation of air.", "content": "Circulation in sanitary ventilation by bactericidal irradiation of air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004247"}
{"pmid": "21004248", "title": "Studies on the chemotherapy of experimental virus infections; the effect of certain organic arsenicals on the course of experimental murine poliomyelitis.", "content": "Studies on the chemotherapy of experimental virus infections; the effect of certain organic arsenicals on the course of experimental murine poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004248"}
{"pmid": "21004249", "title": "On the eyes and reactions to light of Proteus anguinus.", "content": "On the eyes and reactions to light of Proteus anguinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004249"}
{"pmid": "21004250", "title": "The anatomical organization of the nervous system of Enteropneusta.", "content": "The anatomical organization of the nervous system of Enteropneusta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004250"}
{"pmid": "21004251", "title": "The design of a microdensitometer.", "content": "The design of a microdensitometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004251"}
{"pmid": "21004252", "title": "An automatic recorder for resistance thermometry.", "content": "An automatic recorder for resistance thermometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004252"}
{"pmid": "21004253", "title": "ELECTRONIC A.C. galvanometer.", "content": "ELECTRONIC A.C. galvanometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004253"}
{"pmid": "21004254", "title": "Organization and support of science in the United States.", "content": "Organization and support of science in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004254"}
{"pmid": "21004255", "title": "RELATION between epidemics of acute bacterial pneumonia and influenza.", "content": "RELATION between epidemics of acute bacterial pneumonia and influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004255"}
{"pmid": "21004256", "title": "On the in vitro proteolysis of egg white.", "content": "On the in vitro proteolysis of egg white.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004256"}
{"pmid": "21004257", "title": "Effect of concentrated urea solution on the precipitating power of antiovalbumin; significance of formation of protein complexes.", "content": "Effect of concentrated urea solution on the precipitating power of antiovalbumin; significance of formation of protein complexes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004257"}
{"pmid": "21004258", "title": "A box trap for cotton rats.", "content": "A box trap for cotton rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004258"}
{"pmid": "21004259", "title": "The organization of biologists.", "content": "The organization of biologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004259"}
{"pmid": "21004260", "title": "Studies on cerebral edema; reaction of the brain to air exposure; pathologic changes.", "content": "Studies on cerebral edema; reaction of the brain to air exposure; pathologic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004260"}
{"pmid": "21004261", "title": "Tremors of combat neuroses; comparison with tremors of paralysis agitans, delirium tremens and the psychoneuroses of civilian life; electromyographic studies.", "content": "Tremors of combat neuroses; comparison with tremors of paralysis agitans, delirium tremens and the psychoneuroses of civilian life; electromyographic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004261"}
{"pmid": "21004262", "title": "Arteriovenous aneurysm of great cerebral vein and arteries of circle of Willis; formation by junction of the great cerebral vein and the straight sinus and by the choroidal arteries and anomalous branches of the posterior cerebral arteries.", "content": "Arteriovenous aneurysm of great cerebral vein and arteries of circle of Willis; formation by junction of the great cerebral vein and the straight sinus and by the choroidal arteries and anomalous branches of the posterior cerebral arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004262"}
{"pmid": "21004264", "title": "Ménière's syndrome; comparison of results of medical and surgical treatment.", "content": "Ménière's syndrome; comparison of results of medical and surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004264"}
{"pmid": "21004263", "title": "Incidence of advanced maternal age in mothers of 1,000 state hospital patients.", "content": "Incidence of advanced maternal age in mothers of 1,000 state hospital patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004263"}
{"pmid": "21004265", "title": "Electroencephalographic localization and differentiation of lesions of frontal lobes; pathologic confirmation.", "content": "Electroencephalographic localization and differentiation of lesions of frontal lobes; pathologic confirmation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004265"}
{"pmid": "21004266", "title": "Schizophrenic reaction syndrome in course of acute demyelination of central nervous system; clinicopathologic report of a case, with brief review of the literature.", "content": "Schizophrenic reaction syndrome in course of acute demyelination of central nervous system; clinicopathologic report of a case, with brief review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004266"}
{"pmid": "21004267", "title": "A visual retention test for clinical use.", "content": "A visual retention test for clinical use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004267"}
{"pmid": "21004268", "title": "Capillaries of the finger nail folds in cases of neurosis, epilepsy and migraine.", "content": "Capillaries of the finger nail folds in cases of neurosis, epilepsy and migraine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004268"}
{"pmid": "21004269", "title": "Curious lesions of the spinal cord; report of 2 cases.", "content": "Curious lesions of the spinal cord; report of 2 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004269"}
{"pmid": "21004270", "title": "Function of the anterior cerebellar lobe.", "content": "Function of the anterior cerebellar lobe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004270"}
{"pmid": "21004271", "title": "Studies on flying personnel with operational fatigue; modification of pentothal therapy.", "content": "Studies on flying personnel with operational fatigue; modification of pentothal therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004271"}
{"pmid": "21004272", "title": "Anoxia and compounds causing mental disorders in man.", "content": "Anoxia and compounds causing mental disorders in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004272"}
{"pmid": "21004273", "title": "Hypnoanalysis as psychotherapy.", "content": "Hypnoanalysis as psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004273"}
{"pmid": "21004274", "title": "Education, re-education and psychotherapy.", "content": "Education, re-education and psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004274"}
{"pmid": "21004275", "title": "TUBERCULOMA of right pons (rostral).", "content": "TUBERCULOMA of right pons (rostral).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004275"}
{"pmid": "21004276", "title": "Industrial psychiatry; a new field for the psychiatrist.", "content": "Industrial psychiatry; a new field for the psychiatrist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004276"}
{"pmid": "21004277", "title": "Electromyographic studies in poliomyelitis.", "content": "Electromyographic studies in poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004277"}
{"pmid": "21004278", "title": "Psychiatric cross section perspectives viewed through juvenile court cases.", "content": "Psychiatric cross section perspectives viewed through juvenile court cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004278"}
{"pmid": "21004279", "title": "Character and the psychopath.", "content": "Character and the psychopath.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004279"}
{"pmid": "21004280", "title": "Science and awareness.", "content": "Science and awareness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004280"}
{"pmid": "21004281", "title": "Central nervous system in acute disseminate lupus erythematosus.", "content": "Central nervous system in acute disseminate lupus erythematosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004281"}
{"pmid": "21004282", "title": "Studies regarding glutamine and ammonia in the cerebrospinal fluid of patients with nervous and mental diseases (with some observations on insulin hypoglycemic shock and oligophrenia phenylpyruvica).", "content": "Studies regarding glutamine and ammonia in the cerebrospinal fluid of patients with nervous and mental diseases (with some observations on insulin hypoglycemic shock and oligophrenia phenylpyruvica).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004282"}
{"pmid": "21004283", "title": "Foster homes for adults; a note on a practitioner's improvisation.", "content": "Foster homes for adults; a note on a practitioner's improvisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004283"}
{"pmid": "21004284", "title": "A fatality incident to electroshock treatment; review of the subject and autopsy report.", "content": "A fatality incident to electroshock treatment; review of the subject and autopsy report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004284"}
{"pmid": "21004285", "title": "Electroconvulsive therapy in the prone position.", "content": "Electroconvulsive therapy in the prone position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004285"}
{"pmid": "21004286", "title": "Electroconvulsive therapy of acute hysteria.", "content": "Electroconvulsive therapy of acute hysteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004286"}
{"pmid": "21004287", "title": "Asthma and solitude; a study of the asthmatic incarcerate.", "content": "Asthma and solitude; a study of the asthmatic incarcerate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004287"}
{"pmid": "21004288", "title": "Amnesic states in war neuroses; the psychogenesis of fugues.", "content": "Amnesic states in war neuroses; the psychogenesis of fugues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004288"}
{"pmid": "21004289", "title": "Repression in prefreudian American psychiatry.", "content": "Repression in prefreudian American psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004289"}
{"pmid": "21004290", "title": "Psychological and psychodynamic aspects of disturbances in the sleep mechanism.", "content": "Psychological and psychodynamic aspects of disturbances in the sleep mechanism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004290"}
{"pmid": "21004291", "title": "Psychoanalytic observations on dreams and psychosomatic reactions in response to hypnotics and anaesthetics.", "content": "Psychoanalytic observations on dreams and psychosomatic reactions in response to hypnotics and anaesthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004291"}
{"pmid": "21004292", "title": "Interpretation of a typical and stereotyped dream met with only during psychoanalysis.", "content": "Interpretation of a typical and stereotyped dream met with only during psychoanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004292"}
{"pmid": "21004293", "title": "The negative in dreams.", "content": "The negative in dreams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004293"}
{"pmid": "21004294", "title": "A mechanism of hysteria elucidated during hypnoanalysis.", "content": "A mechanism of hysteria elucidated during hypnoanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004294"}
{"pmid": "21004295", "title": "Psychoanalysis of a case of paranoia.", "content": "Psychoanalysis of a case of paranoia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004295"}
{"pmid": "21004296", "title": "On the psychology of detective stories and related problems.", "content": "On the psychology of detective stories and related problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004296"}
{"pmid": "21004297", "title": "Some aspects of a psychoanalytic interpretation of music.", "content": "Some aspects of a psychoanalytic interpretation of music.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004297"}
{"pmid": "21004298", "title": "Neurotic pessimism.", "content": "Neurotic pessimism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004298"}
{"pmid": "21004299", "title": "Working through in psychoanalysis.", "content": "Working through in psychoanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004299"}
{"pmid": "21004300", "title": "The hero's rebirth.", "content": "The hero's rebirth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004300"}
{"pmid": "21004301", "title": "The genetic approach in psychoanalysis.", "content": "The genetic approach in psychoanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004301"}
{"pmid": "21004302", "title": "The biological economy of birth.", "content": "The biological economy of birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004302"}
{"pmid": "21004303", "title": "Hospitalism; an inquiry into the genesis of psychiatric conditions in early childhood.", "content": "Hospitalism; an inquiry into the genesis of psychiatric conditions in early childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004303"}
{"pmid": "21004304", "title": "Examination of the Klein system of child psychology.", "content": "Examination of the Klein system of child psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004304"}
{"pmid": "21004305", "title": "Notes on the analytic discovery of a primal scene.", "content": "Notes on the analytic discovery of a primal scene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004305"}
{"pmid": "21004306", "title": "Indications for child analysis.", "content": "Indications for child analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004306"}
{"pmid": "21004307", "title": "Clinical notes on child analysis.", "content": "Clinical notes on child analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004307"}
{"pmid": "21004308", "title": "Analysis of psychogenic anorexia and vomiting in a 4-year-old child.", "content": "Analysis of psychogenic anorexia and vomiting in a 4-year-old child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004308"}
{"pmid": "21004309", "title": "Formation of the antisocial character.", "content": "Formation of the antisocial character.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004309"}
{"pmid": "21004310", "title": "The fantasy of having a twin.", "content": "The fantasy of having a twin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004310"}
{"pmid": "21004311", "title": "The uncompromising demand of a 3-year-old for her own mother.", "content": "The uncompromising demand of a 3-year-old for her own mother.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004311"}
{"pmid": "21004312", "title": "The use of dreams in psychiatric work with children.", "content": "The use of dreams in psychiatric work with children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004312"}
{"pmid": "21004313", "title": "A contribution to the education of a parent.", "content": "A contribution to the education of a parent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004313"}
{"pmid": "21004314", "title": "The reluctance to go to school.", "content": "The reluctance to go to school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004314"}
{"pmid": "21004315", "title": "The means of education.", "content": "The means of education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004315"}
{"pmid": "21004316", "title": "Psychoanalytic education.", "content": "Psychoanalytic education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004316"}
{"pmid": "21004317", "title": "Interpretation and education.", "content": "Interpretation and education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004317"}
{"pmid": "21004318", "title": "Childhood and tradition in 2 American Indian tribes.", "content": "Childhood and tradition in 2 American Indian tribes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004318"}
{"pmid": "21004319", "title": "Transference and group formation in children and adolescents.", "content": "Transference and group formation in children and adolescents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004319"}
{"pmid": "21004320", "title": "The psychology of gang formation and the treatment of juvenile delinquents.", "content": "The psychology of gang formation and the treatment of juvenile delinquents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004320"}
{"pmid": "21004322", "title": "The dysenteries and their treatment.", "content": "The dysenteries and their treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004322"}
{"pmid": "21004321", "title": "Nursing treatment in haematemesis and melaena.", "content": "Nursing treatment in haematemesis and melaena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004321"}
{"pmid": "21004323", "title": "A consideration of childbirth as physiological function.", "content": "A consideration of childbirth as physiological function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004323"}
{"pmid": "21004324", "title": "GOVERNMENT'S code for nursing.", "content": "GOVERNMENT'S code for nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004324"}
{"pmid": "21004325", "title": "Medical diseases of the kidneys; varieties of Bright's disease.", "content": "Medical diseases of the kidneys; varieties of Bright's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004325"}
{"pmid": "21004326", "title": "Care of the aged and infirm.", "content": "Care of the aged and infirm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004326"}
{"pmid": "21004327", "title": "Severe spinal injury complicated by quadriplegia.", "content": "Severe spinal injury complicated by quadriplegia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004327"}
{"pmid": "21004328", "title": "Work in a leper colony in South Africa.", "content": "Work in a leper colony in South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004328"}
{"pmid": "21004329", "title": "Psychology and ward administration.", "content": "Psychology and ward administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004329"}
{"pmid": "21004330", "title": "Response of chronic simple glaucoma to treatment with cyclodiathermy puncture.", "content": "Response of chronic simple glaucoma to treatment with cyclodiathermy puncture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004330"}
{"pmid": "21004331", "title": "Diabetic retinitis.", "content": "Diabetic retinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004331"}
{"pmid": "21004333", "title": "Penetration of penicillin into the eye.", "content": "Penetration of penicillin into the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004333"}
{"pmid": "21004332", "title": "Revaluation of Herbert's flap operation for glaucoma.", "content": "Revaluation of Herbert's flap operation for glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004332"}
{"pmid": "21004334", "title": "Vitamin C saturation and senile cataract.", "content": "Vitamin C saturation and senile cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004334"}
{"pmid": "21004335", "title": "Symmetric defects in the lower lids associated with abnormalities of the zygomatic processes of the temporal bones.", "content": "Symmetric defects in the lower lids associated with abnormalities of the zygomatic processes of the temporal bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004335"}
{"pmid": "21004336", "title": "Value of cultures before operation for cataract.", "content": "Value of cultures before operation for cataract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004336"}
{"pmid": "21004337", "title": "Cavernous degeneration, necrosis and other regressive processes in optic nerve with vascular disease of the eye.", "content": "Cavernous degeneration, necrosis and other regressive processes in optic nerve with vascular disease of the eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004337"}
{"pmid": "21004338", "title": "Effect of anoxia on heterophoria and its analogy with convergent concomitant squint.", "content": "Effect of anoxia on heterophoria and its analogy with convergent concomitant squint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004338"}
{"pmid": "21004339", "title": "Interstitial keratitis treated with subconjunctival injections of penicillin.", "content": "Interstitial keratitis treated with subconjunctival injections of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004339"}
{"pmid": "21004340", "title": "Ophthalmodynamometry.", "content": "Ophthalmodynamometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004340"}
{"pmid": "21004341", "title": "Keratitis due to N-butyl alcohol.", "content": "Keratitis due to N-butyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004341"}
{"pmid": "21004342", "title": "Diagnosis of orbital tumors.", "content": "Diagnosis of orbital tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004342"}
{"pmid": "21004343", "title": "A photoelectric instrument for direct spectrochemical analysis.", "content": "A photoelectric instrument for direct spectrochemical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004343"}
{"pmid": "21004344", "title": "Optics of distilled and natural water.", "content": "Optics of distilled and natural water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004344"}
{"pmid": "21004345", "title": "The significance of emittance in radiation pyrometry.", "content": "The significance of emittance in radiation pyrometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004345"}
{"pmid": "21004346", "title": "Industrial use of radiation pyrometers under non-blackbody conditions.", "content": "Industrial use of radiation pyrometers under non-blackbody conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004346"}
{"pmid": "21004347", "title": "Two criteria for the selection of color vision test plates.", "content": "Two criteria for the selection of color vision test plates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004347"}
{"pmid": "21004348", "title": "Note on MacAdam's determination of chromaticity sensibilities.", "content": "Note on MacAdam's determination of chromaticity sensibilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004348"}
{"pmid": "21004349", "title": "Medical follow-up of hearing tests.", "content": "Medical follow-up of hearing tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004349"}
{"pmid": "21004350", "title": "Hearing conservation at the college level.", "content": "Hearing conservation at the college level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004350"}
{"pmid": "21004351", "title": "A screening survey of organic inpairment.", "content": "A screening survey of organic inpairment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004351"}
{"pmid": "21004352", "title": "Speech disorders in World War II; dysarthria.", "content": "Speech disorders in World War II; dysarthria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004352"}
{"pmid": "21004353", "title": "Infant speech sounds and intelligence.", "content": "Infant speech sounds and intelligence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004353"}
{"pmid": "21004355", "title": "Control of athetotic tremors by sound stimuli.", "content": "Control of athetotic tremors by sound stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004355"}
{"pmid": "21004354", "title": "Subjective observations on cerebral palsy.", "content": "Subjective observations on cerebral palsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004354"}
{"pmid": "21004356", "title": "Speech correction services in State welfare programs.", "content": "Speech correction services in State welfare programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004356"}
{"pmid": "21004357", "title": "Treatment of a child with delayed speech.", "content": "Treatment of a child with delayed speech.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004357"}
{"pmid": "21004358", "title": "Stuttering in twin types.", "content": "Stuttering in twin types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004358"}
{"pmid": "21004359", "title": "The significance of a positional nystagmus in otoneurological diagnosis.", "content": "The significance of a positional nystagmus in otoneurological diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004359"}
{"pmid": "21004360", "title": "The occurrence of spontaneous cerebrospinal rhinorrhea in the literature, the experience of the writer, and other diplomates of the American boards of otolaryngology and neurosurgeons.", "content": "The occurrence of spontaneous cerebrospinal rhinorrhea in the literature, the experience of the writer, and other diplomates of the American boards of otolaryngology and neurosurgeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004360"}
{"pmid": "21004361", "title": "An experiment showing the Bernoulli action in emptying the nasal sinuses.", "content": "An experiment showing the Bernoulli action in emptying the nasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004361"}
{"pmid": "21004362", "title": "Changes in tissues of children deprived of dietary protein.", "content": "Changes in tissues of children deprived of dietary protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004362"}
{"pmid": "21004363", "title": "Studies on the relation of pneumotropic streptococci influenza virus.", "content": "Studies on the relation of pneumotropic streptococci influenza virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004363"}
{"pmid": "21004364", "title": "The development of hemolytic anemia during sulfa medication.", "content": "The development of hemolytic anemia during sulfa medication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004364"}
{"pmid": "21004365", "title": "Myeloid leukemia, probably eosinophilic in character.", "content": "Myeloid leukemia, probably eosinophilic in character.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004365"}
{"pmid": "21004366", "title": "The Weltmann reaction in arthritis.", "content": "The Weltmann reaction in arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004366"}
{"pmid": "21004367", "title": "Pernicious anemia and miliary tuberculosis of the bone marrow organ.", "content": "Pernicious anemia and miliary tuberculosis of the bone marrow organ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004367"}
{"pmid": "21004368", "title": "Heredity of the agglutinogen Rh.", "content": "Heredity of the agglutinogen Rh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004368"}
{"pmid": "21004369", "title": "Tissue changes induced by Senecio riddellii.", "content": "Tissue changes induced by Senecio riddellii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004369"}
{"pmid": "21004370", "title": "New method of preparing Boerner-Jones-Lukens (B-J-L) flocculation antigen.", "content": "New method of preparing Boerner-Jones-Lukens (B-J-L) flocculation antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004370"}
{"pmid": "21004371", "title": "Immediate reinfusion of erythrocytes to the blood donor following plasma separation; preliminary report of a new apparatus.", "content": "Immediate reinfusion of erythrocytes to the blood donor following plasma separation; preliminary report of a new apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004371"}
{"pmid": "21004372", "title": "Detection of Diphyllobothrium latum ova in polarized light.", "content": "Detection of Diphyllobothrium latum ova in polarized light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004372"}
{"pmid": "21004373", "title": "Automatic device for spectrophotometer colorimeter tube (cuvette).", "content": "Automatic device for spectrophotometer colorimeter tube (cuvette).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004373"}
{"pmid": "21004374", "title": "A microtome knife-guard.", "content": "A microtome knife-guard.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004374"}
{"pmid": "21004375", "title": "The conjunctival test as a guide to clinical immunity in hay fever.", "content": "The conjunctival test as a guide to clinical immunity in hay fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004375"}
{"pmid": "21004384", "title": "Effect of excessive ingestion of sodium chloride on the chick, with particular reference to renal changes.", "content": "Effect of excessive ingestion of sodium chloride on the chick, with particular reference to renal changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004384"}
{"pmid": "21004385", "title": "Structural changes in early filariasis.", "content": "Structural changes in early filariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004385"}
{"pmid": "21004386", "title": "Changes in the musculature of the gastrointestinal tract and in the myocardium in progressive muscular dystrophy.", "content": "Changes in the musculature of the gastrointestinal tract and in the myocardium in progressive muscular dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004386"}
{"pmid": "21004387", "title": "Structure of the liver in pellagra.", "content": "Structure of the liver in pellagra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004387"}
{"pmid": "21004388", "title": "Aging processes in the endocrine glands of the guinea pig; the influence of age, sex and pregnancy on the mitotic activity and the histologic structure of the thyroid, parathyroid and adrenal glands.", "content": "Aging processes in the endocrine glands of the guinea pig; the influence of age, sex and pregnancy on the mitotic activity and the histologic structure of the thyroid, parathyroid and adrenal glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004388"}
{"pmid": "21004389", "title": "Regeneration of epidermis of mice under the influence of 20-methylcholanthrene.", "content": "Regeneration of epidermis of mice under the influence of 20-methylcholanthrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004389"}
{"pmid": "21004390", "title": "Microfilarial granuloma of the spleen; observations in 12 additional cases.", "content": "Microfilarial granuloma of the spleen; observations in 12 additional cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004390"}
{"pmid": "21004391", "title": "Bilateral ovarian carcinoma in a 30 week fetus.", "content": "Bilateral ovarian carcinoma in a 30 week fetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004391"}
{"pmid": "21004376", "title": "Mold allergy; clinical analysis.", "content": "Mold allergy; clinical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004376"}
{"pmid": "21004392", "title": "Incorrect diagnosis of mental deficiency and its consequences.", "content": "Incorrect diagnosis of mental deficiency and its consequences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004392"}
{"pmid": "21004393", "title": "Some new clinical observations on hydrops congenitus.", "content": "Some new clinical observations on hydrops congenitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004393"}
{"pmid": "21004380", "title": "Parenteral use of butanefrine in asthma; a comparison with epinephrine.", "content": "Parenteral use of butanefrine in asthma; a comparison with epinephrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004380"}
{"pmid": "21004394", "title": "A comparison of the effects of hospital isolation and home isolation in cases of scarlet fever.", "content": "A comparison of the effects of hospital isolation and home isolation in cases of scarlet fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004394"}
{"pmid": "21004377", "title": "The organic state in the problem of allergy.", "content": "The organic state in the problem of allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004377"}
{"pmid": "21004395", "title": "Non-traumatic subarachnoid hemorrhage in children beyond the neo-natal age.", "content": "Non-traumatic subarachnoid hemorrhage in children beyond the neo-natal age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004395"}
{"pmid": "21004396", "title": "Pre-excitation of the ventricular part of the heart and its occurrence in children.", "content": "Pre-excitation of the ventricular part of the heart and its occurrence in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004396"}
{"pmid": "21004397", "title": "A hospital epidemic of chickenpox.", "content": "A hospital epidemic of chickenpox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004397"}
{"pmid": "21004381", "title": "An unusual effect of aminophylline on the intestinal tract; case report.", "content": "An unusual effect of aminophylline on the intestinal tract; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004381"}
{"pmid": "21004379", "title": "Inhalation of 10 percent carbon dioxide and 90 percent oxygen plus 1:100 glycerinized epinephrine hydrochloride for the relief of asthmatic attacks.", "content": "Inhalation of 10 percent carbon dioxide and 90 percent oxygen plus 1:100 glycerinized epinephrine hydrochloride for the relief of asthmatic attacks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004379"}
{"pmid": "21004399", "title": "Human milk studies; implications of breast feeding and their investigation.", "content": "Human milk studies; implications of breast feeding and their investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004399"}
{"pmid": "21004378", "title": "Penicillin urticaria.", "content": "Penicillin urticaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004378"}
{"pmid": "21004383", "title": "Pedistric allergy; a critical review of recent literature.", "content": "Pedistric allergy; a critical review of recent literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004383"}
{"pmid": "21004400", "title": "Human milk studies; the diet of lactating women and the collection and preparation of food and human milk for analysis.", "content": "Human milk studies; the diet of lactating women and the collection and preparation of food and human milk for analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004400"}
{"pmid": "21004382", "title": "The future of American medicine.", "content": "The future of American medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004382"}
{"pmid": "21004401", "title": "Human milk studies; a simple technic for the manual expression of mother's milk.", "content": "Human milk studies; a simple technic for the manual expression of mother's milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004401"}
{"pmid": "21004402", "title": "Human milk studies; nicotinic acid, pantothenic acid and biotin contents of colostrum and mature human milk.", "content": "Human milk studies; nicotinic acid, pantothenic acid and biotin contents of colostrum and mature human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004402"}
{"pmid": "21004403", "title": "Human milk studies; free and total thiamine contents of colostrum and mature human milk.", "content": "Human milk studies; free and total thiamine contents of colostrum and mature human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004403"}
{"pmid": "21004404", "title": "Human milk studies; free and total riboflavin contents of colostrum and mature human milk.", "content": "Human milk studies; free and total riboflavin contents of colostrum and mature human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004404"}
{"pmid": "21004405", "title": "Human milk studies; ascorbic acid and dehydroascorbic acid in colostrum and mature human milk.", "content": "Human milk studies; ascorbic acid and dehydroascorbic acid in colostrum and mature human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004405"}
{"pmid": "21004406", "title": "Human milk studies; vitamin A and carotenoid contents of colostrum and mature human milk.", "content": "Human milk studies; vitamin A and carotenoid contents of colostrum and mature human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004406"}
{"pmid": "21004407", "title": "Human milk studies; comparative values of bovine and human milks in infant feeding.", "content": "Human milk studies; comparative values of bovine and human milks in infant feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004407"}
{"pmid": "21004414", "title": "Social adjustment of deficient children; a few psychological consequences of the failure.", "content": "Social adjustment of deficient children; a few psychological consequences of the failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004414"}
{"pmid": "21004415", "title": "Cervical gland tuberculosis.", "content": "Cervical gland tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004415"}
{"pmid": "21004416", "title": "Scurvy in rural areas.", "content": "Scurvy in rural areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004416"}
{"pmid": "21004417", "title": "Some outstanding features in the education of the handicapped at Spalding School, Chicago, Illinois.", "content": "Some outstanding features in the education of the handicapped at Spalding School, Chicago, Illinois.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004417"}
{"pmid": "21004418", "title": "Sex hygiene education in junior high school.", "content": "Sex hygiene education in junior high school.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004418"}
{"pmid": "21004420", "title": "TRAINING of apprentices.", "content": "TRAINING of apprentices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004420"}
{"pmid": "21004419", "title": "Evaluation of the tuberculin test.", "content": "Evaluation of the tuberculin test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004419"}
{"pmid": "21004421", "title": "The preparation, properties and use of penicillin.", "content": "The preparation, properties and use of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004421"}
{"pmid": "21004422", "title": "STERILISATION of syringes.", "content": "STERILISATION of syringes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004422"}
{"pmid": "21004423", "title": "Fuchsias for medicine and beauty.", "content": "Fuchsias for medicine and beauty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004423"}
{"pmid": "21004424", "title": "REHABILITATION of service personnel; a summary of the benefits available under Commonwealth legislation.", "content": "REHABILITATION of service personnel; a summary of the benefits available under Commonwealth legislation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004424"}
{"pmid": "21004425", "title": "Pharmacies in Soviet war hospitals.", "content": "Pharmacies in Soviet war hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004425"}
{"pmid": "21004426", "title": "Studies on analgesics; the time-action curves of morphine, codeine, dilaudid and demerol by various methods of administration; analgesic activity of acetylsalicylic acid and aminopyrine.", "content": "Studies on analgesics; the time-action curves of morphine, codeine, dilaudid and demerol by various methods of administration; analgesic activity of acetylsalicylic acid and aminopyrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004426"}
{"pmid": "21004427", "title": "The permeability of mycobacteria to sulfonamides and sulfonamide-like agents.", "content": "The permeability of mycobacteria to sulfonamides and sulfonamide-like agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004427"}
{"pmid": "21004428", "title": "Studies on shock induced by hemorrhage; some properties of a naturally occurring inhibitor of alpha-amino acid oxidase.", "content": "Studies on shock induced by hemorrhage; some properties of a naturally occurring inhibitor of alpha-amino acid oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004428"}
{"pmid": "21004429", "title": "Antithyroid studies; the goitrogenic activity of some thioureas, pyrimidines and miscellaneous compounds.", "content": "Antithyroid studies; the goitrogenic activity of some thioureas, pyrimidines and miscellaneous compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004429"}
{"pmid": "21004430", "title": "Toxicity studies on benzyl benzoate and related benzyl compounds.", "content": "Toxicity studies on benzyl benzoate and related benzyl compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004430"}
{"pmid": "21004431", "title": "The destruction by tyrosinase of the irritant principles of poison ivy and related toxicants.", "content": "The destruction by tyrosinase of the irritant principles of poison ivy and related toxicants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004431"}
{"pmid": "21004432", "title": "The isolation of di (p-chlorophenyl) acetic acid (DDA) from the urine of rabbits poisoned with 2,2 bis (p-chlorophenyl) 1,1,1 trichloroethane (DDT).", "content": "The isolation of di (p-chlorophenyl) acetic acid (DDA) from the urine of rabbits poisoned with 2,2 bis (p-chlorophenyl) 1,1,1 trichloroethane (DDT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004432"}
{"pmid": "21004433", "title": "A comparative study of the effectiveness of 1,3,7 trimethylxanthine and certain dimethylxanthines (1,3 dimethylxanthine and 3,7 dimethylxanthine) against fatigue.", "content": "A comparative study of the effectiveness of 1,3,7 trimethylxanthine and certain dimethylxanthines (1,3 dimethylxanthine and 3,7 dimethylxanthine) against fatigue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004433"}
{"pmid": "21004434", "title": "Pharmacological studies of some benzofuranone derivatives.", "content": "Pharmacological studies of some benzofuranone derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004434"}
{"pmid": "21004435", "title": "The calculation of biological assay results by graphic methods; the all-or-none type of response.", "content": "The calculation of biological assay results by graphic methods; the all-or-none type of response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004435"}
{"pmid": "21004436", "title": "Antithyroid studies; the goitrogenic activity of some imidazoles and benzimidazoles.", "content": "Antithyroid studies; the goitrogenic activity of some imidazoles and benzimidazoles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004436"}
{"pmid": "21004437", "title": "The experimental basis for the quantitative chemotherapy of B. novyi in mice with a comparison of action of penicillin and dichlorphenarsine hydrochloride.", "content": "The experimental basis for the quantitative chemotherapy of B. novyi in mice with a comparison of action of penicillin and dichlorphenarsine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004437"}
{"pmid": "21004438", "title": "Distribution and fate of penicillin in the body.", "content": "Distribution and fate of penicillin in the body.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004438"}
{"pmid": "21004439", "title": "Effect of various electrolytes upon the toxicity of desoxycorticosterone acetate.", "content": "Effect of various electrolytes upon the toxicity of desoxycorticosterone acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004439"}
{"pmid": "21004440", "title": "The blocking action of the cinchona alkaloids and certain related compounds on the cardio-inhibitory vagus endings of the dog.", "content": "The blocking action of the cinchona alkaloids and certain related compounds on the cardio-inhibitory vagus endings of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004440"}
{"pmid": "21004441", "title": "Isopropyl alcohol; acquired tolerance in dogs, rate of disappearance from the blood stream in various species, and effects on successive generation of rats.", "content": "Isopropyl alcohol; acquired tolerance in dogs, rate of disappearance from the blood stream in various species, and effects on successive generation of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004441"}
{"pmid": "21004442", "title": "Further observations on the pressor action of optical isomers of sympathomimetic amines.", "content": "Further observations on the pressor action of optical isomers of sympathomimetic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004442"}
{"pmid": "21004443", "title": "The hydrolysis of demerol by liver in vitro.", "content": "The hydrolysis of demerol by liver in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004443"}
{"pmid": "21004444", "title": "Biological comparison of local anaesthetics.", "content": "Biological comparison of local anaesthetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004444"}
{"pmid": "21004445", "title": "Synthetic substitutes for atropine.", "content": "Synthetic substitutes for atropine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004445"}
{"pmid": "21004449", "title": "Control of the secretion of antidiuretic hormone from the pars nervosa of the pituitary gland.", "content": "Control of the secretion of antidiuretic hormone from the pars nervosa of the pituitary gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004449"}
{"pmid": "21004451", "title": "Genetics and metabolism in Neurospora.", "content": "Genetics and metabolism in Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004451"}
{"pmid": "21004450", "title": "Present views on the mode of action of acetylcholine in the central nervous system.", "content": "Present views on the mode of action of acetylcholine in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004450"}
{"pmid": "21004452", "title": "Relative nutritive values of animal and vegetable fats.", "content": "Relative nutritive values of animal and vegetable fats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004452"}
{"pmid": "21004453", "title": "Interference with biological processes through the use of analogs of essential metabolites.", "content": "Interference with biological processes through the use of analogs of essential metabolites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004453"}
{"pmid": "21004454", "title": "Age and mental ability in superior men.", "content": "Age and mental ability in superior men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004454"}
{"pmid": "21004455", "title": "Comparison of Negro and white recruits on the Army tests given in 1917-1918.", "content": "Comparison of Negro and white recruits on the Army tests given in 1917-1918.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004455"}
{"pmid": "21004456", "title": "Influence of menstruation upon nausea induced from the vestibule.", "content": "Influence of menstruation upon nausea induced from the vestibule.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004456"}
{"pmid": "21004457", "title": "Intensity of attitude as a determinant of decision time.", "content": "Intensity of attitude as a determinant of decision time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004457"}
{"pmid": "21004458", "title": "Proactive inhibition; a function of time-interval.", "content": "Proactive inhibition; a function of time-interval.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004458"}
{"pmid": "21004459", "title": "Effect of speed of rotation and complexity of pattern on the reversals of apparent movement in Lissajou figures.", "content": "Effect of speed of rotation and complexity of pattern on the reversals of apparent movement in Lissajou figures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004459"}
{"pmid": "21004460", "title": "Modified methods of constant and single stimuli in pitch discrimination.", "content": "Modified methods of constant and single stimuli in pitch discrimination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004460"}
{"pmid": "21004461", "title": "Beta apparent movement under binocular, monocular and interocular stimulation.", "content": "Beta apparent movement under binocular, monocular and interocular stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004461"}
{"pmid": "21004462", "title": "Some personality differences in Northern and Southern college students.", "content": "Some personality differences in Northern and Southern college students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004462"}
{"pmid": "21004463", "title": "The assessment of personality.", "content": "The assessment of personality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004463"}
{"pmid": "21004464", "title": "An analysis of youth centre interests.", "content": "An analysis of youth centre interests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004464"}
{"pmid": "21004465", "title": "The educational interests of a group of young industrial workers.", "content": "The educational interests of a group of young industrial workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004465"}
{"pmid": "21004466", "title": "The distribution of intelligence among elementary school children in Northern Ireland.", "content": "The distribution of intelligence among elementary school children in Northern Ireland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004466"}
{"pmid": "21004467", "title": "Some sex differences in attitude towards change of environment among evacuated central school children.", "content": "Some sex differences in attitude towards change of environment among evacuated central school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004467"}
{"pmid": "21004468", "title": "A picture interpretation personality test.", "content": "A picture interpretation personality test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004468"}
{"pmid": "21004478", "title": "A child health program.", "content": "A child health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004478"}
{"pmid": "21004479", "title": "An epidemic of septic sore throat at Salmon Arm, B.C.", "content": "An epidemic of septic sore throat at Salmon Arm, B.C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004479"}
{"pmid": "21004480", "title": "Mortality reductions in Ontario, 1900-1942.", "content": "Mortality reductions in Ontario, 1900-1942.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004480"}
{"pmid": "21004481", "title": "The incidence of pinworm infection in a military camp in Ontario.", "content": "The incidence of pinworm infection in a military camp in Ontario.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004481"}
{"pmid": "21004470", "title": "A study of thought processes in a word association test.", "content": "A study of thought processes in a word association test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004470"}
{"pmid": "21004471", "title": "Restoration of personal integrity, the keynote of psychoanalytic therapy.", "content": "Restoration of personal integrity, the keynote of psychoanalytic therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004471"}
{"pmid": "21004482", "title": "Canadian Public Health Association, 1944-1945.", "content": "Canadian Public Health Association, 1944-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004482"}
{"pmid": "21004483", "title": "Postwar trends in physical education programs.", "content": "Postwar trends in physical education programs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004483"}
{"pmid": "21004484", "title": "Standards in physical education.", "content": "Standards in physical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004484"}
{"pmid": "21004485", "title": "Surgery in the life of to-day.", "content": "Surgery in the life of to-day.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004485"}
{"pmid": "21004469", "title": "The application of teleonomic description to the diagnosis and treatment of emotional instability and personal and social maladjustments.", "content": "The application of teleonomic description to the diagnosis and treatment of emotional instability and personal and social maladjustments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004469"}
{"pmid": "21004486", "title": "The future of the Ministry of Food.", "content": "The future of the Ministry of Food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004486"}
{"pmid": "21004472", "title": "Projective techniques in mental deficiency.", "content": "Projective techniques in mental deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004472"}
{"pmid": "21004473", "title": "A case of paramnesia in Nathaniel Hawthorne.", "content": "A case of paramnesia in Nathaniel Hawthorne.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004473"}
{"pmid": "21004487", "title": "Crime and delinquency.", "content": "Crime and delinquency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004487"}
{"pmid": "21004488", "title": "Public health and its debt to experimental medical research.", "content": "Public health and its debt to experimental medical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004488"}
{"pmid": "21004489", "title": "Cancer in England and Wales.", "content": "Cancer in England and Wales.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004489"}
{"pmid": "21004490", "title": "The staffing of county hospitals.", "content": "The staffing of county hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004490"}
{"pmid": "21004491", "title": "The post-Schick test; its role as an adventitious stimulus.", "content": "The post-Schick test; its role as an adventitious stimulus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004491"}
{"pmid": "21004474", "title": "Some fragments from the life history of a marginal man.", "content": "Some fragments from the life history of a marginal man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004474"}
{"pmid": "21004492", "title": "Anemia and granulocytopenia in rats fed a diet low in pantothenic acid.", "content": "Anemia and granulocytopenia in rats fed a diet low in pantothenic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004492"}
{"pmid": "21004493", "title": "Tsutsugamushi disease (scrub typhus); the effects of an immune rabbit serum in experimentally infected mice.", "content": "Tsutsugamushi disease (scrub typhus); the effects of an immune rabbit serum in experimentally infected mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004493"}
{"pmid": "21004494", "title": "Studies of the role of fungi in pulmonary disease; cross reactions of histoplasmin.", "content": "Studies of the role of fungi in pulmonary disease; cross reactions of histoplasmin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004494"}
{"pmid": "21004495", "title": "Health education in the public health program.", "content": "Health education in the public health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004495"}
{"pmid": "21004496", "title": "Apparent serological heterogeneity among strains of Tsutsugamushi disease (scrub typhus).", "content": "Apparent serological heterogeneity among strains of Tsutsugamushi disease (scrub typhus).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004496"}
{"pmid": "21004497", "title": "An epidemic of a severe pneumonitis in the bayou region of Louisiana.", "content": "An epidemic of a severe pneumonitis in the bayou region of Louisiana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004497"}
{"pmid": "21004498", "title": "Fatigue curve test.", "content": "Fatigue curve test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004498"}
{"pmid": "21004499", "title": "The relationship between success in physical education and selected attitudes expressed by high school freshmen girls.", "content": "The relationship between success in physical education and selected attitudes expressed by high school freshmen girls.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004499"}
{"pmid": "21004500", "title": "Reading difficulty differences of health knowledge tests.", "content": "Reading difficulty differences of health knowledge tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004500"}
{"pmid": "21004501", "title": "A score card for evaluating physical education programs for physically handicapped children.", "content": "A score card for evaluating physical education programs for physically handicapped children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004501"}
{"pmid": "21004502", "title": "Status of the graduate faculty in physical education.", "content": "Status of the graduate faculty in physical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004502"}
{"pmid": "21004503", "title": "Some observations on the sub-endothelial cushions of the umbilical arteries.", "content": "Some observations on the sub-endothelial cushions of the umbilical arteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004503"}
{"pmid": "21004504", "title": "Some features of the spinal nervous system of the foetal whale (Megaptera nodosa).", "content": "Some features of the spinal nervous system of the foetal whale (Megaptera nodosa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004504"}
{"pmid": "21004505", "title": "A second study of the behaviour and fate of skin homografts in rabbits; a report to the War Wounds Committee of the Medical Research Council.", "content": "A second study of the behaviour and fate of skin homografts in rabbits; a report to the War Wounds Committee of the Medical Research Council.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004505"}
{"pmid": "21004506", "title": "Parthenogenesis of atretic ova in the rodent ovary.", "content": "Parthenogenesis of atretic ova in the rodent ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004506"}
{"pmid": "21004507", "title": "Boutons terminaux in the cerebral cortex.", "content": "Boutons terminaux in the cerebral cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004507"}
{"pmid": "21004508", "title": "An outbreak of scrub typhus among Air Force troops in the Southwest Pacific area.", "content": "An outbreak of scrub typhus among Air Force troops in the Southwest Pacific area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004508"}
{"pmid": "21004509", "title": "Notes on filariasis.", "content": "Notes on filariasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004509"}
{"pmid": "21004510", "title": "A roundworm problem in the Philippines.", "content": "A roundworm problem in the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004510"}
{"pmid": "21004511", "title": "SCHISTOSOMIASIS japonica.", "content": "SCHISTOSOMIASIS japonica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004511"}
{"pmid": "21004512", "title": "Oriental schistosomiasis; a clinical report.", "content": "Oriental schistosomiasis; a clinical report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004512"}
{"pmid": "21004513", "title": "Skin reaction to yellow fever vaccine.", "content": "Skin reaction to yellow fever vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004513"}
{"pmid": "21004514", "title": "Is leprosy a threat to the American soldier.", "content": "Is leprosy a threat to the American soldier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004514"}
{"pmid": "21004515", "title": "Amebiasis at a military base in India.", "content": "Amebiasis at a military base in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004515"}
{"pmid": "21004516", "title": "Epidemic of syndrome characterized by lymphadenopathy and lymphocytosis.", "content": "Epidemic of syndrome characterized by lymphadenopathy and lymphocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004516"}
{"pmid": "21004517", "title": "Industrial hygiene at an airbase.", "content": "Industrial hygiene at an airbase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004517"}
{"pmid": "21004519", "title": "Primary pulmonary coccidioidomycosis.", "content": "Primary pulmonary coccidioidomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004519"}
{"pmid": "21004518", "title": "Duties of the veterinary officer in the ATC.", "content": "Duties of the veterinary officer in the ATC.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004518"}
{"pmid": "21004520", "title": "Domestic air transportation of patients.", "content": "Domestic air transportation of patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004520"}
{"pmid": "21004521", "title": "Management of otomycosis.", "content": "Management of otomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004521"}
{"pmid": "21004522", "title": "Portable surgical suction apparatus.", "content": "Portable surgical suction apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004522"}
{"pmid": "21004523", "title": "X-ray department at a redistribution center.", "content": "X-ray department at a redistribution center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004523"}
{"pmid": "21004524", "title": "Filtered ultraviolet lamp constructed in the field.", "content": "Filtered ultraviolet lamp constructed in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004524"}
{"pmid": "21004525", "title": "Penicillin and nonspecific foreign protein fever therapy in treatment of acute and chronic eczematoid dermatoses.", "content": "Penicillin and nonspecific foreign protein fever therapy in treatment of acute and chronic eczematoid dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004525"}
{"pmid": "21004526", "title": "Penicillin troches for gingivitis.", "content": "Penicillin troches for gingivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004526"}
{"pmid": "21004527", "title": "Quinacrine hydrochloride (atabrine) as a malaria suppressive agent.", "content": "Quinacrine hydrochloride (atabrine) as a malaria suppressive agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004527"}
{"pmid": "21004528", "title": "Immunization reaction as a result of egg sensitivity.", "content": "Immunization reaction as a result of egg sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004528"}
{"pmid": "21004529", "title": "An analysis of the mechanism of budding in yeasts and some observations on the structure of the yeast cell.", "content": "An analysis of the mechanism of budding in yeasts and some observations on the structure of the yeast cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004529"}
{"pmid": "21004530", "title": "The production of a penicillin-like factor by dermatophytes.", "content": "The production of a penicillin-like factor by dermatophytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004530"}
{"pmid": "21004531", "title": "The parasitism of Striga hermonthica Benth, on Sorghum spp. under irrigation; preliminary results and light irrigation on Striga attack.", "content": "The parasitism of Striga hermonthica Benth, on Sorghum spp. under irrigation; preliminary results and light irrigation on Striga attack.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004531"}
{"pmid": "21004532", "title": "Black scurf and stem canker of potato (Corticium Solani Bourd, & Galz.); further field studies on the use of clean and contaminated seed potatoes and on the contamination of crop tubers.", "content": "Black scurf and stem canker of potato (Corticium Solani Bourd, & Galz.); further field studies on the use of clean and contaminated seed potatoes and on the contamination of crop tubers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004532"}
{"pmid": "21004533", "title": "Gliotoxin, a fungistatic metabolic product of Trichoderma viride.", "content": "Gliotoxin, a fungistatic metabolic product of Trichoderma viride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004533"}
{"pmid": "21004534", "title": "Studies in the dynamics of disinfection; the reaction between phenol and Bact. coli; the true shape of the probit-log survival-time curve.", "content": "Studies in the dynamics of disinfection; the reaction between phenol and Bact. coli; the true shape of the probit-log survival-time curve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004534"}
{"pmid": "21004535", "title": "The use of abrasives in the transmission of plant viruses.", "content": "The use of abrasives in the transmission of plant viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004535"}
{"pmid": "21004536", "title": "Control of the potato-root eelworm, Heterodera rostochiensis Wollenweber, by allyl isothiocyanate, the mustard oil of Brassica nigra L.", "content": "Control of the potato-root eelworm, Heterodera rostochiensis Wollenweber, by allyl isothiocyanate, the mustard oil of Brassica nigra L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004536"}
{"pmid": "21004537", "title": "Studies upon the copper fungicides; the solution of copper from dressings on the pea seed.", "content": "Studies upon the copper fungicides; the solution of copper from dressings on the pea seed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004537"}
{"pmid": "21004538", "title": "Studies upon the copper fungicides; the penetration of copper into germinating peas.", "content": "Studies upon the copper fungicides; the penetration of copper into germinating peas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004538"}
{"pmid": "21004539", "title": "The mode of action of sheep dips.", "content": "The mode of action of sheep dips.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004539"}
{"pmid": "21004540", "title": "Introduction; the genetic analysis of disease.", "content": "Introduction; the genetic analysis of disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004540"}
{"pmid": "21004541", "title": "Constitution in cattle in relation to pests and diseases.", "content": "Constitution in cattle in relation to pests and diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004541"}
{"pmid": "21004542", "title": "The evolution of male haploidy.", "content": "The evolution of male haploidy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004542"}
{"pmid": "21004543", "title": "Academic instruction in cancer control.", "content": "Academic instruction in cancer control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004543"}
{"pmid": "21004544", "title": "Cancer of the lung.", "content": "Cancer of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004544"}
{"pmid": "21004545", "title": "On the determination of choline in the liver and plasma of the dog.", "content": "On the determination of choline in the liver and plasma of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004545"}
{"pmid": "21004546", "title": "The mechanism of action of the antifatty liver factor of the pancreas; its relation to plasma choline.", "content": "The mechanism of action of the antifatty liver factor of the pancreas; its relation to plasma choline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004546"}
{"pmid": "21004547", "title": "Interaction between proteins and synthetic detergents; molecular-kinetic studies of serum albumin-sodium dodecyl sulfate mixtures.", "content": "Interaction between proteins and synthetic detergents; molecular-kinetic studies of serum albumin-sodium dodecyl sulfate mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004547"}
{"pmid": "21004548", "title": "Growth requirements of a purine-deficient strain of Neurospora.", "content": "Growth requirements of a purine-deficient strain of Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004548"}
{"pmid": "21004549", "title": "The utilization of acetic acid for the synthesis of fatty acids.", "content": "The utilization of acetic acid for the synthesis of fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004549"}
{"pmid": "21004550", "title": "Ultrafiltrability of thiouracil in human serum; determination of thiouracil.", "content": "Ultrafiltrability of thiouracil in human serum; determination of thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004550"}
{"pmid": "21004551", "title": "The inability of human or beef globin to support normal hematopoiesis in the rat without added isoleucine.", "content": "The inability of human or beef globin to support normal hematopoiesis in the rat without added isoleucine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004551"}
{"pmid": "21004552", "title": "The utilization of d-amino acids by man.", "content": "The utilization of d-amino acids by man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004552"}
{"pmid": "21004553", "title": "The determination of oxybiotin in the presence of biotin.", "content": "The determination of oxybiotin in the presence of biotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004553"}
{"pmid": "21004554", "title": "Desthiobiotin in the biosynthesis of biotin.", "content": "Desthiobiotin in the biosynthesis of biotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004554"}
{"pmid": "21004555", "title": "The function of pyridoxine; conversion of members of the vitamin B6 group into codecarboxylase.", "content": "The function of pyridoxine; conversion of members of the vitamin B6 group into codecarboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004555"}
{"pmid": "21004556", "title": "The synthesis and configuration of d-14-methylpalmitic acid and its identity with the natural acid from wool fat.", "content": "The synthesis and configuration of d-14-methylpalmitic acid and its identity with the natural acid from wool fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004556"}
{"pmid": "21004557", "title": "The influence of insulin and epinephrine upon some phosphorus fractions of the blood.", "content": "The influence of insulin and epinephrine upon some phosphorus fractions of the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004557"}
{"pmid": "21004558", "title": "The mechanism of action of the antifatty liver factor of the pancreas; free methionine prevents fatty livers in completely depancreatized dogs maintained with insulin and fed a lean meat diet.", "content": "The mechanism of action of the antifatty liver factor of the pancreas; free methionine prevents fatty livers in completely depancreatized dogs maintained with insulin and fed a lean meat diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004558"}
{"pmid": "21004559", "title": "Studies on vitamin Bc conjugase from chicken pancreas.", "content": "Studies on vitamin Bc conjugase from chicken pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004559"}
{"pmid": "21004560", "title": "The effect of dietary proteins and amino acids on liver fat.", "content": "The effect of dietary proteins and amino acids on liver fat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004560"}
{"pmid": "21004561", "title": "Ribonucleinase.", "content": "Ribonucleinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004561"}
{"pmid": "21004562", "title": "Ribonucleinase; mononucleotides in commercial ribonucleic acids and their effect on ribonucleinase.", "content": "Ribonucleinase; mononucleotides in commercial ribonucleic acids and their effect on ribonucleinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004562"}
{"pmid": "21004563", "title": "The colorimetric assay of urinary corticosteroid-like substances.", "content": "The colorimetric assay of urinary corticosteroid-like substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004563"}
{"pmid": "21004564", "title": "Essential groups of crystalline chymotrypsin.", "content": "Essential groups of crystalline chymotrypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004564"}
{"pmid": "21004565", "title": "The veratrine alkaloids; the alkaloids of Veratrum viride.", "content": "The veratrine alkaloids; the alkaloids of Veratrum viride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004565"}
{"pmid": "21004566", "title": "The mineral composition of human epidermis.", "content": "The mineral composition of human epidermis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004566"}
{"pmid": "21004571", "title": "The determination of ascorbic acid in small amounts of blood serum.", "content": "The determination of ascorbic acid in small amounts of blood serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004571"}
{"pmid": "21004567", "title": "The estimation of free formaldehyde by diffusion.", "content": "The estimation of free formaldehyde by diffusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004567"}
{"pmid": "21004568", "title": "Preparation of pituitary thyrotropic hormone.", "content": "Preparation of pituitary thyrotropic hormone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004568"}
{"pmid": "21004569", "title": "A method for the determination of copper in blood serum.", "content": "A method for the determination of copper in blood serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004569"}
{"pmid": "21004572", "title": "Photometric determination of potassium in biological materials.", "content": "Photometric determination of potassium in biological materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004572"}
{"pmid": "21004570", "title": "Growth and lipotropism; the dietary requirements of methionine, cystine, and choline.", "content": "Growth and lipotropism; the dietary requirements of methionine, cystine, and choline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004570"}
{"pmid": "21004573", "title": "Aerobic phosphorylations in tissue slices.", "content": "Aerobic phosphorylations in tissue slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004573"}
{"pmid": "21004574", "title": "The effect of anterior pituitary extract and of insulin on the hexokinase reaction.", "content": "The effect of anterior pituitary extract and of insulin on the hexokinase reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004574"}
{"pmid": "21004575", "title": "Methylation of guanidoacetic acid by homocystine plus choline with rat liver slices.", "content": "Methylation of guanidoacetic acid by homocystine plus choline with rat liver slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004575"}
{"pmid": "21004576", "title": "The adsorption of phosphates by enamel, dentin, and bone; the adsorption rates from concentrated solution.", "content": "The adsorption of phosphates by enamel, dentin, and bone; the adsorption rates from concentrated solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004576"}
{"pmid": "21004577", "title": "3-substituted thianaphthenes.", "content": "3-substituted thianaphthenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004577"}
{"pmid": "21004578", "title": "Studies in ozonolysis; action of ozone on solvents used in ozonization.", "content": "Studies in ozonolysis; action of ozone on solvents used in ozonization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004578"}
{"pmid": "21004579", "title": "Behavior of some carbamic acid derivatives of 2-amino-phenol.", "content": "Behavior of some carbamic acid derivatives of 2-amino-phenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004579"}
{"pmid": "21004580", "title": "Analgesics; aminophthalidylalkanes.", "content": "Analgesics; aminophthalidylalkanes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004580"}
{"pmid": "21004582", "title": "The search for superior drugs for tropical diseases; further experiments in the quinoline group.", "content": "The search for superior drugs for tropical diseases; further experiments in the quinoline group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004582"}
{"pmid": "21004581", "title": "The structure of affinin, the insecticidal amide from Erigeron affinis D. C.", "content": "The structure of affinin, the insecticidal amide from Erigeron affinis D. C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004581"}
{"pmid": "21004583", "title": "The reaction of styrene with aldehydes.", "content": "The reaction of styrene with aldehydes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004583"}
{"pmid": "21004584", "title": "The sulfomethylation reaction.", "content": "The sulfomethylation reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004584"}
{"pmid": "21004585", "title": "Some derivatives of 3-methylisoquinoline.", "content": "Some derivatives of 3-methylisoquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004585"}
{"pmid": "21004586", "title": "The condensation of carbonyl compounds with amides; aliphatic aldehydes and pyruvic acid with aliphatic carbamates.", "content": "The condensation of carbonyl compounds with amides; aliphatic aldehydes and pyruvic acid with aliphatic carbamates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004586"}
{"pmid": "21004587", "title": "Solubilities of high molecular weight primary aliphatic amine hydrochlorides in ethanol.", "content": "Solubilities of high molecular weight primary aliphatic amine hydrochlorides in ethanol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004587"}
{"pmid": "21004588", "title": "Occipital and cervical anchorage and their application to the orthodontic problem.", "content": "Occipital and cervical anchorage and their application to the orthodontic problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004588"}
{"pmid": "21004589", "title": "The maxillator; a new instrument for measuring the Frankfort-mandibular base angle, the incisor-mandibular base angle, and other component parts of the face and jaws.", "content": "The maxillator; a new instrument for measuring the Frankfort-mandibular base angle, the incisor-mandibular base angle, and other component parts of the face and jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004589"}
{"pmid": "21004590", "title": "An adjustable locking bracket for use with multiple band therapy.", "content": "An adjustable locking bracket for use with multiple band therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004590"}
{"pmid": "21004591", "title": "Arrest of hemorrhage in two hemophiliacs following dental extractions.", "content": "Arrest of hemorrhage in two hemophiliacs following dental extractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004591"}
{"pmid": "21004592", "title": "Experimental chronic fluorine intoxication; effect on bones and teeth.", "content": "Experimental chronic fluorine intoxication; effect on bones and teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004592"}
{"pmid": "21004593", "title": "Chemotherapy in oral surgery.", "content": "Chemotherapy in oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004593"}
{"pmid": "21004594", "title": "The prevention of endodontal pathosis.", "content": "The prevention of endodontal pathosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004594"}
{"pmid": "21004596", "title": "A cleft palate prosthesis; treatment of a case with a hollow-ball obturator.", "content": "A cleft palate prosthesis; treatment of a case with a hollow-ball obturator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004596"}
{"pmid": "21004595", "title": "Cancer of the oral mucosa and circumoral areas.", "content": "Cancer of the oral mucosa and circumoral areas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004595"}
{"pmid": "21004597", "title": "Complete luxation of the maxillary anterior teeth.", "content": "Complete luxation of the maxillary anterior teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004597"}
{"pmid": "21004598", "title": "A line of disturbed dentinal structure.", "content": "A line of disturbed dentinal structure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004598"}
{"pmid": "21004600", "title": "Epithelial cyst of the pulp.", "content": "Epithelial cyst of the pulp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004600"}
{"pmid": "21004602", "title": "A compound composite odontome.", "content": "A compound composite odontome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004602"}
{"pmid": "21004599", "title": "Oral hygiene for partial denture wearers.", "content": "Oral hygiene for partial denture wearers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004599"}
{"pmid": "21004603", "title": "Eruption of upper second premolars in spite of retained second deciduous molars.", "content": "Eruption of upper second premolars in spite of retained second deciduous molars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004603"}
{"pmid": "21004604", "title": "An impression technique for flabby ridges.", "content": "An impression technique for flabby ridges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004604"}
{"pmid": "21004601", "title": "Orthodontics and the school child: a survey of 680 children.", "content": "Orthodontics and the school child: a survey of 680 children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004601"}
{"pmid": "21004605", "title": "A case of ulcerative stomatitis treated with penicillin.", "content": "A case of ulcerative stomatitis treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004605"}
{"pmid": "21004606", "title": "An aptitude testing program for the dental schools.", "content": "An aptitude testing program for the dental schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004606"}
{"pmid": "21004607", "title": "Control of mandibular roentgenograms by fixed positioning.", "content": "Control of mandibular roentgenograms by fixed positioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004607"}
{"pmid": "21004608", "title": "A flexible rest in the removable partial denture.", "content": "A flexible rest in the removable partial denture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004608"}
{"pmid": "21004609", "title": "Correction of extreme protrusion of the maxilla and atrophy of the left mandible.", "content": "Correction of extreme protrusion of the maxilla and atrophy of the left mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004609"}
{"pmid": "21004610", "title": "Early removal of third molars for caries prevention.", "content": "Early removal of third molars for caries prevention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004610"}
{"pmid": "21004611", "title": "Peripheral seal impression technique, using the alginates.", "content": "Peripheral seal impression technique, using the alginates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004611"}
{"pmid": "21004612", "title": "General anaesthesia in dental surgery.", "content": "General anaesthesia in dental surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004612"}
{"pmid": "21004613", "title": "Bone injection for painless dentistry.", "content": "Bone injection for painless dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004613"}
{"pmid": "21004614", "title": "Early syphilis resistant to treatment with penicillin; report of a case.", "content": "Early syphilis resistant to treatment with penicillin; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004614"}
{"pmid": "21004615", "title": "Experimental studies on chromoblastomycosis.", "content": "Experimental studies on chromoblastomycosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004615"}
{"pmid": "21004616", "title": "Surface active agents; chemical types and applications.", "content": "Surface active agents; chemical types and applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004616"}
{"pmid": "21004617", "title": "Hair root strength and the menstrual cycle.", "content": "Hair root strength and the menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004617"}
{"pmid": "21004618", "title": "The evaluation of intraderm sulphur for acne vulgaris.", "content": "The evaluation of intraderm sulphur for acne vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004618"}
{"pmid": "21004621", "title": "Determination of blood cholesterol by the Bloor and Leiboff methods; a comparative study.", "content": "Determination of blood cholesterol by the Bloor and Leiboff methods; a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004621"}
{"pmid": "21004619", "title": "Normal hemoglobin values for young women.", "content": "Normal hemoglobin values for young women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004619"}
{"pmid": "21004623", "title": "Food and health problems of industry.", "content": "Food and health problems of industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004623"}
{"pmid": "21004624", "title": "Budgetary and dietary surveys of families and individuals.", "content": "Budgetary and dietary surveys of families and individuals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004624"}
{"pmid": "21004620", "title": "Laboratory identification of intestinal protozoan parasites.", "content": "Laboratory identification of intestinal protozoan parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004620"}
{"pmid": "21004622", "title": "A source of blood for culture media.", "content": "A source of blood for culture media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004622"}
{"pmid": "21004625", "title": "Allocation of food within the family.", "content": "Allocation of food within the family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004625"}
{"pmid": "21004626", "title": "The statistical validity of methods used in budgetary and dietary surveys.", "content": "The statistical validity of methods used in budgetary and dietary surveys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004626"}
{"pmid": "21004627", "title": "Family income and expenditure on food.", "content": "Family income and expenditure on food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004627"}
{"pmid": "21004629", "title": "Some effects of inanition and their treatment.", "content": "Some effects of inanition and their treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004629"}
{"pmid": "21004628", "title": "Relation of expenditure on food to other family expenditure.", "content": "Relation of expenditure on food to other family expenditure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004628"}
{"pmid": "21004630", "title": "Nutritional researches in Vienna after the First World War.", "content": "Nutritional researches in Vienna after the First World War.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004630"}
{"pmid": "21004632", "title": "The use of ascorbic acid in gingival repair and in the healing of tooth extraction wounds.", "content": "The use of ascorbic acid in gingival repair and in the healing of tooth extraction wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004632"}
{"pmid": "21004631", "title": "Influence of nutrition on parodontal health.", "content": "Influence of nutrition on parodontal health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004631"}
{"pmid": "21004633", "title": "Chronic fluorine intoxication in sheep and its effect upon the teeth.", "content": "Chronic fluorine intoxication in sheep and its effect upon the teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004633"}
{"pmid": "21004634", "title": "Diet and the calcified dental tissues.", "content": "Diet and the calcified dental tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004634"}
{"pmid": "21004635", "title": "Individual dietary surveys.", "content": "Individual dietary surveys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004635"}
{"pmid": "21004636", "title": "Survey of methods used in preparing and cooking vegetables.", "content": "Survey of methods used in preparing and cooking vegetables.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004636"}
{"pmid": "21004638", "title": "School diets in elementary schools.", "content": "School diets in elementary schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004638"}
{"pmid": "21004637", "title": "Laboratory assessment of nutritive value of meals as eaten.", "content": "Laboratory assessment of nutritive value of meals as eaten.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004637"}
{"pmid": "21004639", "title": "Hospital diets.", "content": "Hospital diets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004639"}
{"pmid": "21004640", "title": "Diet and tuberculosis.", "content": "Diet and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004640"}
{"pmid": "21004641", "title": "Tuberculosis in Scotland; present position.", "content": "Tuberculosis in Scotland; present position.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004641"}
{"pmid": "21004642", "title": "The clinical position with particular reference to diet.", "content": "The clinical position with particular reference to diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004642"}
{"pmid": "21004643", "title": "The progress of eradication of tuberculosis from cattle in Great Britain.", "content": "The progress of eradication of tuberculosis from cattle in Great Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004643"}
{"pmid": "21004644", "title": "Tuberculosis and pasteurization of the milk supply.", "content": "Tuberculosis and pasteurization of the milk supply.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004644"}
{"pmid": "21004645", "title": "The microbiological aspect of rumen digestion.", "content": "The microbiological aspect of rumen digestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004645"}
{"pmid": "21004646", "title": "The formation of protein.", "content": "The formation of protein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004646"}
{"pmid": "21004647", "title": "Synthesis of vitamins by microorganisms of the alimentary tract.", "content": "Synthesis of vitamins by microorganisms of the alimentary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004647"}
{"pmid": "21004648", "title": "The production and absorption of the volatile acids in the rumen.", "content": "The production and absorption of the volatile acids in the rumen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004648"}
{"pmid": "21004649", "title": "Volatile fatty acids in the rumen of the sheep.", "content": "Volatile fatty acids in the rumen of the sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004649"}
{"pmid": "21004650", "title": "The utilization of volatile acids.", "content": "The utilization of volatile acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004650"}
{"pmid": "21004651", "title": "Pruritus ani; a clinical study.", "content": "Pruritus ani; a clinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004651"}
{"pmid": "21004652", "title": "Dibutoline; effect on insulin-induced gastric hypermotility in human subjects, and other observations.", "content": "Dibutoline; effect on insulin-induced gastric hypermotility in human subjects, and other observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004652"}
{"pmid": "21004654", "title": "Pancreatic lithiasis; a report of two cases in young adults.", "content": "Pancreatic lithiasis; a report of two cases in young adults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004654"}
{"pmid": "21004653", "title": "The effect of succinyl-sulfathiazole on the volume of intestinal gas in normal young men.", "content": "The effect of succinyl-sulfathiazole on the volume of intestinal gas in normal young men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004653"}
{"pmid": "21004655", "title": "Serial tests of hippuric acid formation in hepatitis after intravenous sodium benzoate.", "content": "Serial tests of hippuric acid formation in hepatitis after intravenous sodium benzoate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004655"}
{"pmid": "21004656", "title": "The effects upon small intestine of rapid intravenous injections of casein hydrolysate.", "content": "The effects upon small intestine of rapid intravenous injections of casein hydrolysate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004656"}
{"pmid": "21004657", "title": "A study of the alleged role of caffeine in the pathogenesis of gastric ulcer.", "content": "A study of the alleged role of caffeine in the pathogenesis of gastric ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004657"}
{"pmid": "21004658", "title": "Is the patient with tuberculosis or peptic ulcer more subject to atherosclerosis because of his diet rich in milk?", "content": "Is the patient with tuberculosis or peptic ulcer more subject to atherosclerosis because of his diet rich in milk?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004658"}
{"pmid": "21004660", "title": "Treatment of posttraumatic Simmonds' disease with methyl testosterone linguets.", "content": "Treatment of posttraumatic Simmonds' disease with methyl testosterone linguets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004660"}
{"pmid": "21004659", "title": "Review of a symposium on ulcer.", "content": "Review of a symposium on ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004659"}
{"pmid": "21004663", "title": "Effect of thiouracil on human tissues.", "content": "Effect of thiouracil on human tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004663"}
{"pmid": "21004661", "title": "The accumulation, interpretation, and presentation of data pertaining to metabolic balances, notably those of calcium, phosphorus, and nitrogen.", "content": "The accumulation, interpretation, and presentation of data pertaining to metabolic balances, notably those of calcium, phosphorus, and nitrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004661"}
{"pmid": "21004662", "title": "Pheochromocytoma.", "content": "Pheochromocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004662"}
{"pmid": "21004667", "title": "Loneliness and the serviceman's wife.", "content": "Loneliness and the serviceman's wife.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004667"}
{"pmid": "21004668", "title": "Counseling with the returned serviceman and his wife.", "content": "Counseling with the returned serviceman and his wife.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004668"}
{"pmid": "21004670", "title": "Counseling in the premarital interview.", "content": "Counseling in the premarital interview.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004670"}
{"pmid": "21004669", "title": "Methods for effective counseling.", "content": "Methods for effective counseling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004669"}
{"pmid": "21004671", "title": "The treatment of furunculosis with sulphur.", "content": "The treatment of furunculosis with sulphur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004671"}
{"pmid": "21004672", "title": "Iodine.", "content": "Iodine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004672"}
{"pmid": "21004673", "title": "Homeopathy among the ancient Hindus and Arabians.", "content": "Homeopathy among the ancient Hindus and Arabians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004673"}
{"pmid": "21004676", "title": "Unusual tumor in rabbit.", "content": "Unusual tumor in rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004676"}
{"pmid": "21004674", "title": "The general practitioner as psychiatric counselor.", "content": "The general practitioner as psychiatric counselor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004674"}
{"pmid": "21004675", "title": "Indications for cholangiography.", "content": "Indications for cholangiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004675"}
{"pmid": "21004677", "title": "What the surgeon must expect of the general practitioner.", "content": "What the surgeon must expect of the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004677"}
{"pmid": "21004664", "title": "Simulated blood pressure responses in lie-detector tests and a method for their detection.", "content": "Simulated blood pressure responses in lie-detector tests and a method for their detection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004664"}
{"pmid": "21004678", "title": "Hospital management of acute urinary retention due to vesical neck obstruction.", "content": "Hospital management of acute urinary retention due to vesical neck obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004678"}
{"pmid": "21004679", "title": "Highlights on surgery of the colon.", "content": "Highlights on surgery of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004679"}
{"pmid": "21004680", "title": "Civic responsibilities and opportunities of the osteopathic physician from the guidance counselor's viewpoint.", "content": "Civic responsibilities and opportunities of the osteopathic physician from the guidance counselor's viewpoint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004680"}
{"pmid": "21004681", "title": "The voluntary hospital in the future.", "content": "The voluntary hospital in the future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004681"}
{"pmid": "21004682", "title": "St. Mary's of London.", "content": "St. Mary's of London.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004682"}
{"pmid": "21004683", "title": "The standard nomenclature of disease and operations.", "content": "The standard nomenclature of disease and operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004683"}
{"pmid": "21004665", "title": "An unusual suicide.", "content": "An unusual suicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004665"}
{"pmid": "21004666", "title": "The United States Supreme Court interpretation of admissibility of criminal confessions.", "content": "The United States Supreme Court interpretation of admissibility of criminal confessions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004666"}
{"pmid": "21004684", "title": "NEW Runnymede Hospital for the care of the chronically ill.", "content": "NEW Runnymede Hospital for the care of the chronically ill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004684"}
{"pmid": "21004685", "title": "BRITISH labour Government to replace health insurance by state medicine plan.", "content": "BRITISH labour Government to replace health insurance by state medicine plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004685"}
{"pmid": "21004686", "title": "Population density and the size of hospital communities.", "content": "Population density and the size of hospital communities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004686"}
{"pmid": "21004687", "title": "ROENTGEN'S ray celebrates golden jubilee.", "content": "ROENTGEN'S ray celebrates golden jubilee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004687"}
{"pmid": "21004688", "title": "The shadowy form of consent in emergency operations.", "content": "The shadowy form of consent in emergency operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004688"}
{"pmid": "21004689", "title": "Mental patients read? They will.", "content": "Mental patients read? They will.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004689"}
{"pmid": "21004690", "title": "Vision new era of x-ray progress; 50 anniversary of Roentgen's discovery marks threshold of stimulating developments.", "content": "Vision new era of x-ray progress; 50 anniversary of Roentgen's discovery marks threshold of stimulating developments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004690"}
{"pmid": "21004691", "title": "SEVEN insurance companies to offer uniform policy including medical and hospital care.", "content": "SEVEN insurance companies to offer uniform policy including medical and hospital care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004691"}
{"pmid": "21004692", "title": "Postwar status of the Catholic hospital.", "content": "Postwar status of the Catholic hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004692"}
{"pmid": "21004693", "title": "Mental health in the convent.", "content": "Mental health in the convent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004693"}
{"pmid": "21004694", "title": "The graduate nurse.", "content": "The graduate nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004694"}
{"pmid": "21004696", "title": "The problem of noise in the modern hospital.", "content": "The problem of noise in the modern hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004696"}
{"pmid": "21004695", "title": "Recruitment of student nurses.", "content": "Recruitment of student nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004695"}
{"pmid": "21004697", "title": "Education and efficiency in bedside nursing.", "content": "Education and efficiency in bedside nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004697"}
{"pmid": "21004698", "title": "The education of physician veterans.", "content": "The education of physician veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004698"}
{"pmid": "21004699", "title": "Tuberculosis in Greece.", "content": "Tuberculosis in Greece.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004699"}
{"pmid": "21004700", "title": "The so-called tropical eosinophilia is a mere modality of Loeffler's syndrome.", "content": "The so-called tropical eosinophilia is a mere modality of Loeffler's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004700"}
{"pmid": "21004701", "title": "Hepatic amoebiasis.", "content": "Hepatic amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004701"}
{"pmid": "21004703", "title": "The food deficiency and intestinal parasitosis (anquilostoma and amoeba) in the aetiology of the duodenal ulcer.", "content": "The food deficiency and intestinal parasitosis (anquilostoma and amoeba) in the aetiology of the duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004703"}
{"pmid": "21004702", "title": "Operations for reducing the size of the foetus.", "content": "Operations for reducing the size of the foetus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004702"}
{"pmid": "21004704", "title": "Use of magnesium sulphate in unhealthy ulcers and sores.", "content": "Use of magnesium sulphate in unhealthy ulcers and sores.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004704"}
{"pmid": "21004705", "title": "Ozaena.", "content": "Ozaena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004705"}
{"pmid": "21004707", "title": "Physical therapy in rheumatoid arthritis.", "content": "Physical therapy in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004707"}
{"pmid": "21004706", "title": "The origin of the Madras General Hospital.", "content": "The origin of the Madras General Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004706"}
{"pmid": "21004708", "title": "Spa treatment of rheumatic diseases in the United States; representative spas.", "content": "Spa treatment of rheumatic diseases in the United States; representative spas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004708"}
{"pmid": "21004709", "title": "Palindromic rheumatism.", "content": "Palindromic rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004709"}
{"pmid": "21004710", "title": "Studies on neuromuscular dysfunction; neostigmine therapy of acute and chronic cervical intramuscular fibrositis.", "content": "Studies on neuromuscular dysfunction; neostigmine therapy of acute and chronic cervical intramuscular fibrositis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004710"}
{"pmid": "21004711", "title": "ADVANCES in electrodiagnosis.", "content": "ADVANCES in electrodiagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004711"}
{"pmid": "21004712", "title": "Studies on patients convalescent from fracture; the urinary excretion of calcium and phosphorus.", "content": "Studies on patients convalescent from fracture; the urinary excretion of calcium and phosphorus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004712"}
{"pmid": "21004715", "title": "The microdetermination of antimony.", "content": "The microdetermination of antimony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004715"}
{"pmid": "21004713", "title": "Comparison of antithyroid action of thioureas and allied substances.", "content": "Comparison of antithyroid action of thioureas and allied substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004713"}
{"pmid": "21004714", "title": "Brachymetopody.", "content": "Brachymetopody.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004714"}
{"pmid": "21004716", "title": "The treatment of behavior problems in children.", "content": "The treatment of behavior problems in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004716"}
{"pmid": "21004717", "title": "Exotic diseases in returning servicemen.", "content": "Exotic diseases in returning servicemen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004717"}
{"pmid": "21004719", "title": "The 39th General Hospital.", "content": "The 39th General Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004719"}
{"pmid": "21004718", "title": "Experiences at Nagasaki, Japan.", "content": "Experiences at Nagasaki, Japan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004718"}
{"pmid": "21004720", "title": "Pneumonia and empyema due to beta hemolytic streptococcus.", "content": "Pneumonia and empyema due to beta hemolytic streptococcus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004720"}
{"pmid": "21004722", "title": "Medical care of veterans.", "content": "Medical care of veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004722"}
{"pmid": "21004721", "title": "A new arthroplasty for small joints.", "content": "A new arthroplasty for small joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004721"}
{"pmid": "21004727", "title": "Malaria in Abyssinia.", "content": "Malaria in Abyssinia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004727"}
{"pmid": "21004728", "title": "Malarial infectivity in African soldiers in a hyper-endemic area.", "content": "Malarial infectivity in African soldiers in a hyper-endemic area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004728"}
{"pmid": "21004729", "title": "The pursuit of pestis.", "content": "The pursuit of pestis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004729"}
{"pmid": "21004730", "title": "Penicillin in the treatment of gonorrhoea.", "content": "Penicillin in the treatment of gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004730"}
{"pmid": "21004731", "title": "The future of post-graduate education in Edinburgh.", "content": "The future of post-graduate education in Edinburgh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004731"}
{"pmid": "21004733", "title": "Some unusual forms of dermatitis.", "content": "Some unusual forms of dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004733"}
{"pmid": "21004734", "title": "Pyoderma gangrenosum.", "content": "Pyoderma gangrenosum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004734"}
{"pmid": "21004732", "title": "Nucleoproteins in growth and development.", "content": "Nucleoproteins in growth and development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004732"}
{"pmid": "21004735", "title": "The problem of oral infection and its relation to systemic diseases.", "content": "The problem of oral infection and its relation to systemic diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004735"}
{"pmid": "21004725", "title": "The surgical treatment of gastrojejunal ulcer.", "content": "The surgical treatment of gastrojejunal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004725"}
{"pmid": "21004736", "title": "Wound infection; the tissue swab.", "content": "Wound infection; the tissue swab.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004736"}
{"pmid": "21004726", "title": "Cervicofacial actinomycosis; successfully treated by penicillin and repeated aspirations.", "content": "Cervicofacial actinomycosis; successfully treated by penicillin and repeated aspirations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004726"}
{"pmid": "21004737", "title": "On the significance of nutritional deficiency in diabetes.", "content": "On the significance of nutritional deficiency in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004737"}
{"pmid": "21004723", "title": "Procurement and assignment.", "content": "Procurement and assignment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004723"}
{"pmid": "21004738", "title": "Experimental investigations on the pathogenesis of infarcts.", "content": "Experimental investigations on the pathogenesis of infarcts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004738"}
{"pmid": "21004739", "title": "Experiments supporting the phase boundary theory of the electrical potential in nerve.", "content": "Experiments supporting the phase boundary theory of the electrical potential in nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004739"}
{"pmid": "21004724", "title": "Hyperinsulinism.", "content": "Hyperinsulinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004724"}
{"pmid": "21004740", "title": "Observations upon the formation, storage and excretion of creatine and creatinine in the rat in relation to phosphate and carbohydrate metabolism.", "content": "Observations upon the formation, storage and excretion of creatine and creatinine in the rat in relation to phosphate and carbohydrate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004740"}
{"pmid": "21004741", "title": "Further studies of the relation between creatine-creatinine metabolism and several body measurements.", "content": "Further studies of the relation between creatine-creatinine metabolism and several body measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004741"}
{"pmid": "21004742", "title": "The procaine esterase test in toxic goiter and carcinoma.", "content": "The procaine esterase test in toxic goiter and carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004742"}
{"pmid": "21004743", "title": "The pneumo-cardiogram.", "content": "The pneumo-cardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004743"}
{"pmid": "21004744", "title": "Comparison between the external pneumo-cardiogram and the intrapneumothorax pneumo-cardiogram.", "content": "Comparison between the external pneumo-cardiogram and the intrapneumothorax pneumo-cardiogram.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004744"}
{"pmid": "21004745", "title": "The phlebogram and the intra-pneumothorax pneumo-cardiogram; a comparative study.", "content": "The phlebogram and the intra-pneumothorax pneumo-cardiogram; a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004745"}
{"pmid": "21004746", "title": "A comparison of the pneumo-cardiogram and the phlebogram in cardiac patients.", "content": "A comparison of the pneumo-cardiogram and the phlebogram in cardiac patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004746"}
{"pmid": "21004764", "title": "The petit mal epilepsies; their treatment with tridione.", "content": "The petit mal epilepsies; their treatment with tridione.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004764"}
{"pmid": "21004765", "title": "Early filariasis in young soldiers.", "content": "Early filariasis in young soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004765"}
{"pmid": "21004766", "title": "Large scale testing for Rh negative blood.", "content": "Large scale testing for Rh negative blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004766"}
{"pmid": "21004768", "title": "Beryllium poisoning.", "content": "Beryllium poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004768"}
{"pmid": "21004767", "title": "Phthalylsulfathiazole (sulfathialidine); clinical, chemical and bacteriologic evaluations in infectious diseases of the colon.", "content": "Phthalylsulfathiazole (sulfathialidine); clinical, chemical and bacteriologic evaluations in infectious diseases of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004767"}
{"pmid": "21004769", "title": "UNTOWARD reactions attributable to atabrine.", "content": "UNTOWARD reactions attributable to atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004769"}
{"pmid": "21004770", "title": "Penicillin ointment in the treatment of impetigo neonatorum.", "content": "Penicillin ointment in the treatment of impetigo neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004770"}
{"pmid": "21004772", "title": "REGIMENTATION of the practice of medicine.", "content": "REGIMENTATION of the practice of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004772"}
{"pmid": "21004773", "title": "Creeping eruption.", "content": "Creeping eruption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004773"}
{"pmid": "21004771", "title": "PLANS for cooperation between teaching institutions and veterans' hospitals.", "content": "PLANS for cooperation between teaching institutions and veterans' hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004771"}
{"pmid": "21004774", "title": "Heat disease.", "content": "Heat disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004774"}
{"pmid": "21004775", "title": "LIBEL; letter by attending physician to successor regarding treatment given patient not libelous; [Texas, 1945].", "content": "LIBEL; letter by attending physician to successor regarding treatment given patient not libelous; [Texas, 1945].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004775"}
{"pmid": "21004776", "title": "A brief discussion of thermal burns.", "content": "A brief discussion of thermal burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004776"}
{"pmid": "21004777", "title": "Modern concepts of cardiovascular disease; heart failure.", "content": "Modern concepts of cardiovascular disease; heart failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004777"}
{"pmid": "21004778", "title": "A history of medicine in Duval County, VII.", "content": "A history of medicine in Duval County, VII.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004778"}
{"pmid": "21004779", "title": "Studies on the readministration of sulfathiazole.", "content": "Studies on the readministration of sulfathiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004779"}
{"pmid": "21004780", "title": "Role of the sanatorium in the postwar period.", "content": "Role of the sanatorium in the postwar period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004780"}
{"pmid": "21004781", "title": "Surgical treatment of carcinoma of the rectum.", "content": "Surgical treatment of carcinoma of the rectum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004781"}
{"pmid": "21004782", "title": "Hypertensive heart disease; case report.", "content": "Hypertensive heart disease; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004782"}
{"pmid": "21004783", "title": "The consideration of two cardiac diseases amenable to surgical treatment.", "content": "The consideration of two cardiac diseases amenable to surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004783"}
{"pmid": "21004784", "title": "Factors in prognosis in coronary disease.", "content": "Factors in prognosis in coronary disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004784"}
{"pmid": "21004786", "title": "Objective tests of cardiac function.", "content": "Objective tests of cardiac function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004786"}
{"pmid": "21004785", "title": "Management of the common cardiac irregularities.", "content": "Management of the common cardiac irregularities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004785"}
{"pmid": "21004787", "title": "Rupture of heart: review and case report.", "content": "Rupture of heart: review and case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004787"}
{"pmid": "21004789", "title": "The treatment of rheumatic fever.", "content": "The treatment of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004789"}
{"pmid": "21004788", "title": "Digitalis: its legitimate field of usefulness.", "content": "Digitalis: its legitimate field of usefulness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004788"}
{"pmid": "21004790", "title": "On the founding of a Variety Club Heart Hospital at the University of Minnesota.", "content": "On the founding of a Variety Club Heart Hospital at the University of Minnesota.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004790"}
{"pmid": "21004791", "title": "Poliomyelitis.", "content": "Poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004791"}
{"pmid": "21004792", "title": "Lupus erythematosus disseminata; with case presentation.", "content": "Lupus erythematosus disseminata; with case presentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004792"}
{"pmid": "21004793", "title": "Etiology, pathogenesis, and pathology of granuloma venereum.", "content": "Etiology, pathogenesis, and pathology of granuloma venereum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004793"}
{"pmid": "21004794", "title": "Benign esophageal strictures.", "content": "Benign esophageal strictures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004794"}
{"pmid": "21004795", "title": "Amino acids; their clinical indications and uses.", "content": "Amino acids; their clinical indications and uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004795"}
{"pmid": "21004796", "title": "The returning veteran.", "content": "The returning veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004796"}
{"pmid": "21004797", "title": "Essential hypertension and its surgical treatment.", "content": "Essential hypertension and its surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004797"}
{"pmid": "21004798", "title": "The importance of minimal tuberculosis.", "content": "The importance of minimal tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004798"}
{"pmid": "21004799", "title": "Getting the maximum benefit from bad rest in the treatment of pulmonary tuberculosis.", "content": "Getting the maximum benefit from bad rest in the treatment of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004799"}
{"pmid": "21004800", "title": "Serodiagnosis in syphillis.", "content": "Serodiagnosis in syphillis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004800"}
{"pmid": "21004801", "title": "Surgical treatment of hyperthyroidism.", "content": "Surgical treatment of hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004801"}
{"pmid": "21004802", "title": "Rheumatic fever and heart disease.", "content": "Rheumatic fever and heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004802"}
{"pmid": "21004803", "title": "Waking temperature in relation to female fecundity.", "content": "Waking temperature in relation to female fecundity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004803"}
{"pmid": "21004804", "title": "Ovarian function and body temperature.", "content": "Ovarian function and body temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004804"}
{"pmid": "21004805", "title": "Infections of the superficial palmar space.", "content": "Infections of the superficial palmar space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004805"}
{"pmid": "21004806", "title": "Treatment of epididymitis.", "content": "Treatment of epididymitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004806"}
{"pmid": "21004807", "title": "Thermogenic effect of progesterone.", "content": "Thermogenic effect of progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004807"}
{"pmid": "21004808", "title": "HOSPITALS; more surveys of regions.", "content": "HOSPITALS; more surveys of regions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004808"}
{"pmid": "21004826", "title": "Treatment of spastic paralysis with special reference to nerve resection.", "content": "Treatment of spastic paralysis with special reference to nerve resection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004826"}
{"pmid": "21004827", "title": "Fracture of the acetabulum with dislocation of the hip and sciatic nerve involvement.", "content": "Fracture of the acetabulum with dislocation of the hip and sciatic nerve involvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004827"}
{"pmid": "21004828", "title": "New hope for spinal cord sufferers.", "content": "New hope for spinal cord sufferers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004828"}
{"pmid": "21004829", "title": "Carotid pressure and the relief of headache.", "content": "Carotid pressure and the relief of headache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004829"}
{"pmid": "21004830", "title": "TREATMENT of cancer of the cervix of the uterus.", "content": "TREATMENT of cancer of the cervix of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004830"}
{"pmid": "21004831", "title": "Uterosalpingography.", "content": "Uterosalpingography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004831"}
{"pmid": "21004832", "title": "Practical points in the differential diagnosis and treatment of appendicitis.", "content": "Practical points in the differential diagnosis and treatment of appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004832"}
{"pmid": "21004833", "title": "Should we have a medical school?", "content": "Should we have a medical school?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004833"}
{"pmid": "21004834", "title": "Dermatome skin grafts for burns in patients prepared with dry dressings and with and without penicillin.", "content": "Dermatome skin grafts for burns in patients prepared with dry dressings and with and without penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004834"}
{"pmid": "21004835", "title": "Nutritional defects among children in Vermont.", "content": "Nutritional defects among children in Vermont.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004835"}
{"pmid": "21004836", "title": "Portal cirrhosis; clinicopathological exercises.", "content": "Portal cirrhosis; clinicopathological exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004836"}
{"pmid": "21004837", "title": "Carcinoma of sigmoid, with ileocolic fistula; clinicopathological exercises.", "content": "Carcinoma of sigmoid, with ileocolic fistula; clinicopathological exercises.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004837"}
{"pmid": "21004839", "title": "Parathyroid adenoma; a clinical and biochemical discussion.", "content": "Parathyroid adenoma; a clinical and biochemical discussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004839"}
{"pmid": "21004838", "title": "Psychiatry in North Carolina.", "content": "Psychiatry in North Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004838"}
{"pmid": "21004840", "title": "Acute incomplete inversion of the puerperal uterus.", "content": "Acute incomplete inversion of the puerperal uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004840"}
{"pmid": "21004841", "title": "Female venereal prophylaxis and feminine hygiene.", "content": "Female venereal prophylaxis and feminine hygiene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004841"}
{"pmid": "21004842", "title": "EVOLUTION of the aseptic principle in surgery.", "content": "EVOLUTION of the aseptic principle in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004842"}
{"pmid": "21004844", "title": "SURGICAL treatment of hypertension.", "content": "SURGICAL treatment of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004844"}
{"pmid": "21004843", "title": "A summary of the problems of sulfa and penicillin fastness.", "content": "A summary of the problems of sulfa and penicillin fastness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004843"}
{"pmid": "21004845", "title": "Investigation of blood transfusion reactions.", "content": "Investigation of blood transfusion reactions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004845"}
{"pmid": "21004847", "title": "Rapid and intensive treatment of syphilis and gonorrhea; report of 748 discharged cases, Clark County, Vancouver Health Department.", "content": "Rapid and intensive treatment of syphilis and gonorrhea; report of 748 discharged cases, Clark County, Vancouver Health Department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004847"}
{"pmid": "21004846", "title": "Ombredanne operation for undescended testicle (cryptorchidism).", "content": "Ombredanne operation for undescended testicle (cryptorchidism).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004846"}
{"pmid": "21004848", "title": "Correction of chordee and hypospadias.", "content": "Correction of chordee and hypospadias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004848"}
{"pmid": "21004849", "title": "SYRINGES.", "content": "SYRINGES.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004849"}
{"pmid": "21004850", "title": "The sequelae of diseases contracted in the Middle East.", "content": "The sequelae of diseases contracted in the Middle East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004850"}
{"pmid": "21004851", "title": "The diagnosis and treatment of chronic amoebiasis.", "content": "The diagnosis and treatment of chronic amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004851"}
{"pmid": "21004853", "title": "Skin and the Solomons.", "content": "Skin and the Solomons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004853"}
{"pmid": "21004852", "title": "Middle meningeal haemorrhage.", "content": "Middle meningeal haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004852"}
{"pmid": "21004854", "title": "An application of the stretch reflex to the identification of a lesion of the upper motor neurone.", "content": "An application of the stretch reflex to the identification of a lesion of the upper motor neurone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004854"}
{"pmid": "21004855", "title": "Mastoidectomy simplified.", "content": "Mastoidectomy simplified.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004855"}
{"pmid": "21004856", "title": "Retroperitoneal chylous cyst.", "content": "Retroperitoneal chylous cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004856"}
{"pmid": "21004857", "title": "Pregnancy in diabetes.", "content": "Pregnancy in diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004857"}
{"pmid": "21004858", "title": "An unusual case of appendicitis.", "content": "An unusual case of appendicitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004858"}
{"pmid": "21004859", "title": "Diabetes with extreme insulin resistance due to thyrotoxicosis.", "content": "Diabetes with extreme insulin resistance due to thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004859"}
{"pmid": "21004860", "title": "Tumour of the small bowel causing intussusception.", "content": "Tumour of the small bowel causing intussusception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004860"}
{"pmid": "21004861", "title": "Vaginal or abdominal hysterectomy?", "content": "Vaginal or abdominal hysterectomy?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004861"}
{"pmid": "21004863", "title": "The art of artificial pneumothorax.", "content": "The art of artificial pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004863"}
{"pmid": "21004862", "title": "The treatment of asthma.", "content": "The treatment of asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004862"}
{"pmid": "21004864", "title": "The diagnosis of anaemia.", "content": "The diagnosis of anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004864"}
{"pmid": "21004865", "title": "The treatment of anaemia.", "content": "The treatment of anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004865"}
{"pmid": "21004866", "title": "Anaemia in childhood.", "content": "Anaemia in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004866"}
{"pmid": "21004867", "title": "Purpura.", "content": "Purpura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004867"}
{"pmid": "21004868", "title": "Glandular fever (infectious mononucleosis).", "content": "Glandular fever (infectious mononucleosis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004868"}
{"pmid": "21004871", "title": "The control of the common fevers of childhood.", "content": "The control of the common fevers of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004871"}
{"pmid": "21004869", "title": "Diet and physique.", "content": "Diet and physique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004869"}
{"pmid": "21004870", "title": "The psychosomatic approach in gynaecological practice.", "content": "The psychosomatic approach in gynaecological practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004870"}
{"pmid": "21004876", "title": "An enquiry into the causes and effects of variolae vaccinae.", "content": "An enquiry into the causes and effects of variolae vaccinae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004876"}
{"pmid": "21004877", "title": "Thrombosis and pulmonary embolism.", "content": "Thrombosis and pulmonary embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004877"}
{"pmid": "21004878", "title": "Carriers of Entamoeba histolytica in Africans of Northern Rhodesia.", "content": "Carriers of Entamoeba histolytica in Africans of Northern Rhodesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004878"}
{"pmid": "21004879", "title": "Medical research in physical education; health and efficiency; a comparative study of clinical status, standards of growth, and of physical performance of 1,495 South African Bantu school-children.", "content": "Medical research in physical education; health and efficiency; a comparative study of clinical status, standards of growth, and of physical performance of 1,495 South African Bantu school-children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004879"}
{"pmid": "21004880", "title": "The response to antisyphilitic treatment in the Bantu.", "content": "The response to antisyphilitic treatment in the Bantu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004880"}
{"pmid": "21004881", "title": "The treatment of gastro-enteritis with sulphadiazine; a clinic survey of 102 cases.", "content": "The treatment of gastro-enteritis with sulphadiazine; a clinic survey of 102 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004881"}
{"pmid": "21004882", "title": "Simple dextrocardia with transposition of the viscera.", "content": "Simple dextrocardia with transposition of the viscera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004882"}
{"pmid": "21004883", "title": "NATAL Coastal Branch newsletter.", "content": "NATAL Coastal Branch newsletter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004883"}
{"pmid": "21004884", "title": "Projective techniques and the medical psychologist.", "content": "Projective techniques and the medical psychologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004884"}
{"pmid": "21004886", "title": "Appendicitis mortality.", "content": "Appendicitis mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004886"}
{"pmid": "21004885", "title": "Experiences as chief of the surgical service of a 2000-bed Army general hospital on the Island of Saipan.", "content": "Experiences as chief of the surgical service of a 2000-bed Army general hospital on the Island of Saipan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004885"}
{"pmid": "21004887", "title": "Metabolic disturbances in infective hepatitis.", "content": "Metabolic disturbances in infective hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004887"}
{"pmid": "21004888", "title": "Problems in foetal life.", "content": "Problems in foetal life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004888"}
{"pmid": "21004890", "title": "Some observations on pending medical legislation and medical trends.", "content": "Some observations on pending medical legislation and medical trends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004890"}
{"pmid": "21004889", "title": "Crystalluria in the Southwest Pacific.", "content": "Crystalluria in the Southwest Pacific.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004889"}
{"pmid": "21004891", "title": "Non-malignant, segmental, ulcerative lesions of the bowel.", "content": "Non-malignant, segmental, ulcerative lesions of the bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004891"}
{"pmid": "21004892", "title": "Horace Wells and his discovery of anesthesia.", "content": "Horace Wells and his discovery of anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004892"}
{"pmid": "21004893", "title": "The treatment of crushing injuries of the extremities.", "content": "The treatment of crushing injuries of the extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004893"}
{"pmid": "21004894", "title": "Traumatic sub-capsular hematoma of the spleen.", "content": "Traumatic sub-capsular hematoma of the spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004894"}
{"pmid": "21004895", "title": "Malignant nephrosclerosis.", "content": "Malignant nephrosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004895"}
{"pmid": "21004896", "title": "Carcinoma of the tail of the pancreas.", "content": "Carcinoma of the tail of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004896"}
{"pmid": "21004897", "title": "Psychiatry for the general practitioner.", "content": "Psychiatry for the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004897"}
{"pmid": "21004898", "title": "Psychiatry and public health.", "content": "Psychiatry and public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004898"}
{"pmid": "21004900", "title": "Some common mechanisms seen in functional disorders.", "content": "Some common mechanisms seen in functional disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004900"}
{"pmid": "21004899", "title": "Mental illness; a public health problem.", "content": "Mental illness; a public health problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004899"}
{"pmid": "21004901", "title": "Is psychiatry a medical luxury?", "content": "Is psychiatry a medical luxury?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004901"}
{"pmid": "21004902", "title": "Some important new and old information about cancer.", "content": "Some important new and old information about cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004902"}
{"pmid": "21004903", "title": "Pentothal at war in the tropics.", "content": "Pentothal at war in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004903"}
{"pmid": "21004904", "title": "The Rh factor; a transfusion puzzle.", "content": "The Rh factor; a transfusion puzzle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004904"}
{"pmid": "21004905", "title": "Paintings of Army medicine; VI.", "content": "Paintings of Army medicine; VI.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004905"}
{"pmid": "21004906", "title": "204th General Hospital on Guam.", "content": "204th General Hospital on Guam.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004906"}
{"pmid": "21004907", "title": "Tuberculosis in German prison camps.", "content": "Tuberculosis in German prison camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004907"}
{"pmid": "21004909", "title": "Chronic meningococcemia; presentation of case and discussion.", "content": "Chronic meningococcemia; presentation of case and discussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004909"}
{"pmid": "21004908", "title": "Reconditioning neuropsychiatric patients in the Army.", "content": "Reconditioning neuropsychiatric patients in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004908"}
{"pmid": "21004910", "title": "Procaine infiltration in the treatment of acute sprains.", "content": "Procaine infiltration in the treatment of acute sprains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004910"}
{"pmid": "21004911", "title": "A case report of dissecting aneurysm of the femoral artery of undetermined etiology and with unusual symptomatology.", "content": "A case report of dissecting aneurysm of the femoral artery of undetermined etiology and with unusual symptomatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004911"}
{"pmid": "21004912", "title": "Toothaches at low atmospheric pressures.", "content": "Toothaches at low atmospheric pressures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004912"}
{"pmid": "21004913", "title": "A study of camptocormia with presentation of three postspinal cases.", "content": "A study of camptocormia with presentation of three postspinal cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004913"}
{"pmid": "21004914", "title": "Meningococcemia with four case reports.", "content": "Meningococcemia with four case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004914"}
{"pmid": "21004915", "title": "Aneurism of the palmar arteries; report of case.", "content": "Aneurism of the palmar arteries; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004915"}
{"pmid": "21004916", "title": "Procaine toxicity with report of a near fatal case.", "content": "Procaine toxicity with report of a near fatal case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004916"}
{"pmid": "21004917", "title": "Venereal disease control survey in a battalion.", "content": "Venereal disease control survey in a battalion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004917"}
{"pmid": "21004918", "title": "The value of music in the resocialization and rehabilitation of the mentally ill.", "content": "The value of music in the resocialization and rehabilitation of the mentally ill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004918"}
{"pmid": "21004919", "title": "The application of the Xanthydrol-KOH-pyridine method to the determination of 2,2, bis (p-chlorophenyl) 1,1,1 trichlorethane (DDT) in water.", "content": "The application of the Xanthydrol-KOH-pyridine method to the determination of 2,2, bis (p-chlorophenyl) 1,1,1 trichlorethane (DDT) in water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004919"}
{"pmid": "21004920", "title": "An improvised fracture table.", "content": "An improvised fracture table.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004920"}
{"pmid": "21004921", "title": "Extra-genital transmission of syphilis; case report.", "content": "Extra-genital transmission of syphilis; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004921"}
{"pmid": "21004922", "title": "Ring injuries.", "content": "Ring injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004922"}
{"pmid": "21004923", "title": "A new surgeon's metal locator.", "content": "A new surgeon's metal locator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004923"}
{"pmid": "21004924", "title": "A compact, sterilizable bone plate and screw holding box.", "content": "A compact, sterilizable bone plate and screw holding box.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004924"}
{"pmid": "21004937", "title": "MEDICAL and sanitary data on Italy.", "content": "MEDICAL and sanitary data on Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004937"}
{"pmid": "21004938", "title": "Interaction of sex, shape, and weight genes in watermelon.", "content": "Interaction of sex, shape, and weight genes in watermelon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004938"}
{"pmid": "21004939", "title": "Some factors affecting the insecticidal action of pyrethrum extracts on the beet leafhopper.", "content": "Some factors affecting the insecticidal action of pyrethrum extracts on the beet leafhopper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004939"}
{"pmid": "21004943", "title": "Removing some of the barriers to crossability in plants.", "content": "Removing some of the barriers to crossability in plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004943"}
{"pmid": "21004941", "title": "Suggested terms for the interpretation of speciation phenomena.", "content": "Suggested terms for the interpretation of speciation phenomena.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004941"}
{"pmid": "21004945", "title": "The numbers of vertebrae in primates.", "content": "The numbers of vertebrae in primates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004945"}
{"pmid": "21004944", "title": "Inheritance of factors involved in one type of heterocaryotic vigor.", "content": "Inheritance of factors involved in one type of heterocaryotic vigor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004944"}
{"pmid": "21004942", "title": "Scab of Cinchona in South America caused by Elsinoë.", "content": "Scab of Cinchona in South America caused by Elsinoë.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004942"}
{"pmid": "21004940", "title": "Science and the world of 1950.", "content": "Science and the world of 1950.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004940"}
{"pmid": "21004946", "title": "The biochemistry of muscle training.", "content": "The biochemistry of muscle training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004946"}
{"pmid": "21004947", "title": "The role of amino acids and amides in the metabolism of ammonium absorbed by Zea mays L.", "content": "The role of amino acids and amides in the metabolism of ammonium absorbed by Zea mays L.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004947"}
{"pmid": "21004950", "title": "The continuous cultivation of micro-organisms.", "content": "The continuous cultivation of micro-organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004950"}
{"pmid": "21004949", "title": "An antibiotic from a bee pathogen.", "content": "An antibiotic from a bee pathogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004949"}
{"pmid": "21004948", "title": "Cytoplasmic diseases and cancer.", "content": "Cytoplasmic diseases and cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004948"}
{"pmid": "21004951", "title": "The small mounds of the Gulf Coastal Plain.", "content": "The small mounds of the Gulf Coastal Plain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004951"}
{"pmid": "21004952", "title": "An unusual action of amphetamine.", "content": "An unusual action of amphetamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004952"}
{"pmid": "21004953", "title": "Bal (British anti-lewisite).", "content": "Bal (British anti-lewisite).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004953"}
{"pmid": "21004954", "title": "Marihuana activity of cannabinol.", "content": "Marihuana activity of cannabinol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004954"}
{"pmid": "21004957", "title": "Heated, avirulent antigens for complement-fixation tests with certain encephalitis viruses.", "content": "Heated, avirulent antigens for complement-fixation tests with certain encephalitis viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004957"}
{"pmid": "21004958", "title": "The rate of water loss from the respiratory tract of man living in a subtropical climate.", "content": "The rate of water loss from the respiratory tract of man living in a subtropical climate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004958"}
{"pmid": "21004955", "title": "Some effects of salts on true cholinesterase.", "content": "Some effects of salts on true cholinesterase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004955"}
{"pmid": "21004956", "title": "The effect of corn steep liquor ash on penicillin production.", "content": "The effect of corn steep liquor ash on penicillin production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004956"}
{"pmid": "21004959", "title": "A new absorbable material for use in neurological and general surgery.", "content": "A new absorbable material for use in neurological and general surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004959"}
{"pmid": "21004960", "title": "A note on the natural occurrence of fluoroacetic acid, the acid of the new rodenticide 1080.", "content": "A note on the natural occurrence of fluoroacetic acid, the acid of the new rodenticide 1080.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004960"}
{"pmid": "21004961", "title": "Early observations on antibiotic substances in Penicillium glaucum and other organisms against a virus.", "content": "Early observations on antibiotic substances in Penicillium glaucum and other organisms against a virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004961"}
{"pmid": "21004962", "title": "Chiasmatypy or the doctrine of delayed action fertilization.", "content": "Chiasmatypy or the doctrine of delayed action fertilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004962"}
{"pmid": "21004963", "title": "Tropical diseases and geopathology.", "content": "Tropical diseases and geopathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004963"}
{"pmid": "21004964", "title": "Oral penicillin; a comparison of various modes of administration.", "content": "Oral penicillin; a comparison of various modes of administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004964"}
{"pmid": "21004965", "title": "Impairment of reproduction in rats by ingestion of lead.", "content": "Impairment of reproduction in rats by ingestion of lead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004965"}
{"pmid": "21004968", "title": "Osteopathy and university presidents.", "content": "Osteopathy and university presidents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004968"}
{"pmid": "21004966", "title": "Antagonism between heparin and plasma trypsin.", "content": "Antagonism between heparin and plasma trypsin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004966"}
{"pmid": "21004969", "title": "Is the giant catfish, Silurus glanis, a predator on man?", "content": "Is the giant catfish, Silurus glanis, a predator on man?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004969"}
{"pmid": "21004970", "title": "Causation, chance, determinism, and freedom in nature.", "content": "Causation, chance, determinism, and freedom in nature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004970"}
{"pmid": "21004967", "title": "The use of charcoal treated peptons in microbiological assays.", "content": "The use of charcoal treated peptons in microbiological assays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004967"}
{"pmid": "21004971", "title": "The relation of national prohibition to mental disease.", "content": "The relation of national prohibition to mental disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004971"}
{"pmid": "21004972", "title": "Transformation in science.", "content": "Transformation in science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004972"}
{"pmid": "21004973", "title": "Freedom of research.", "content": "Freedom of research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004973"}
{"pmid": "21004974", "title": "The genes of plenty.", "content": "The genes of plenty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004974"}
{"pmid": "21004975", "title": "Characteristics of locomotion of white blood cells.", "content": "Characteristics of locomotion of white blood cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004975"}
{"pmid": "21004976", "title": "Studies on an anophthalmic strain of mice; associated cranial nerves and brain centers.", "content": "Studies on an anophthalmic strain of mice; associated cranial nerves and brain centers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004976"}
{"pmid": "21004977", "title": "Innervation of insect hearts.", "content": "Innervation of insect hearts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004977"}
{"pmid": "21004979", "title": "The nuclear pattern and the fiber connections of certain non-cortical areas of the telencephalon of the mink (Mustela vison).", "content": "The nuclear pattern and the fiber connections of certain non-cortical areas of the telencephalon of the mink (Mustela vison).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004979"}
{"pmid": "21004980", "title": "The pathology of injury to nerve induced by cold.", "content": "The pathology of injury to nerve induced by cold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004980"}
{"pmid": "21004981", "title": "Degeneration of the basal ganglia in monkeys from chronic carbon disulfide poisoning.", "content": "Degeneration of the basal ganglia in monkeys from chronic carbon disulfide poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004981"}
{"pmid": "21004978", "title": "Collateral nerve fibers within septum dorsale of the spinal cord and medulla oblongata and their connections.", "content": "Collateral nerve fibers within septum dorsale of the spinal cord and medulla oblongata and their connections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004978"}
{"pmid": "21004982", "title": "Toxic-productive encephalitis; a pathologic study.", "content": "Toxic-productive encephalitis; a pathologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004982"}
{"pmid": "21004983", "title": "Blood vessel hyperplasia masking glioblastoma multiforme; report of a case.", "content": "Blood vessel hyperplasia masking glioblastoma multiforme; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004983"}
{"pmid": "21004984", "title": "Intrasellar meningioma and multiple cerebral glioblastomas.", "content": "Intrasellar meningioma and multiple cerebral glioblastomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004984"}
{"pmid": "21004985", "title": "Cerebellar atrophy; an analysis of the various forms and an analytical scheme for their study; review.", "content": "Cerebellar atrophy; an analysis of the various forms and an analytical scheme for their study; review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004985"}
{"pmid": "21004986", "title": "Hemosiderin and tissue iron in the brain, its relationship, occurrence and importance; a study on 93 human brains.", "content": "Hemosiderin and tissue iron in the brain, its relationship, occurrence and importance; a study on 93 human brains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004986"}
{"pmid": "21004987", "title": "Occurrence and distribution of acid-fast pigment in the central nervous system.", "content": "Occurrence and distribution of acid-fast pigment in the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004987"}
{"pmid": "21004988", "title": "The influence of hypothalamic stimulation on cortically induced movements and on action potentials of the cortex.", "content": "The influence of hypothalamic stimulation on cortically induced movements and on action potentials of the cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004988"}
{"pmid": "21004989", "title": "Transsynaptic and direct stimulation of post-fibres in the artificial synapse formed by severed mammaliam nerve.", "content": "Transsynaptic and direct stimulation of post-fibres in the artificial synapse formed by severed mammaliam nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004989"}
{"pmid": "21004990", "title": "Modification by electrotonus of the transmission in the artificial synapse formed by severed mammalian nerve.", "content": "Modification by electrotonus of the transmission in the artificial synapse formed by severed mammalian nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004990"}
{"pmid": "21004991", "title": "The localization of the premotor interneurons discharging through the peroneal nerve.", "content": "The localization of the premotor interneurons discharging through the peroneal nerve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004991"}
{"pmid": "21004992", "title": "Distribution of internuncial activity in a multineuron reflex chain.", "content": "Distribution of internuncial activity in a multineuron reflex chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004992"}
{"pmid": "21004993", "title": "The relations between multiple innervation and segmental response of skeletal muscle of the dog.", "content": "The relations between multiple innervation and segmental response of skeletal muscle of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004993"}
{"pmid": "21004994", "title": "Anatomic and physiologic properties of cutaneo-visceral vasomotor reflex arcs.", "content": "Anatomic and physiologic properties of cutaneo-visceral vasomotor reflex arcs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004994"}
{"pmid": "21004995", "title": "Further investigations on diencephalic-cortical relations and their significance for the problem on emotion.", "content": "Further investigations on diencephalic-cortical relations and their significance for the problem on emotion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004995"}
{"pmid": "21004996", "title": "Relation of electroencephalogram to photometrically observed vasomotor changes in the brain.", "content": "Relation of electroencephalogram to photometrically observed vasomotor changes in the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004996"}
{"pmid": "21004997", "title": "The acoustic projection system; a comparative study.", "content": "The acoustic projection system; a comparative study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004997"}
{"pmid": "21004998", "title": "Hormonal modifications of social behavior; the effect of sex-hormone administration on the social status of a male castrate chimpanzee.", "content": "Hormonal modifications of social behavior; the effect of sex-hormone administration on the social status of a male castrate chimpanzee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004998"}
{"pmid": "21004999", "title": "Sleep paralysis and combat fatigue.", "content": "Sleep paralysis and combat fatigue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21004999"}
{"pmid": "21005000", "title": "Correlation between emotions and carbohydrate metabolism in two cases of diabetes mellitus.", "content": "Correlation between emotions and carbohydrate metabolism in two cases of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005000"}
{"pmid": "21005001", "title": "Effects on industrial production of the administration of Delta5 pregnenolone to factory workers.", "content": "Effects on industrial production of the administration of Delta5 pregnenolone to factory workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005001"}
{"pmid": "21005002", "title": "Effect of pregnenolone on the ability to perform prolonged psychomotor tests.", "content": "Effect of pregnenolone on the ability to perform prolonged psychomotor tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005002"}
{"pmid": "21005004", "title": "The adjustments of the older nurse.", "content": "The adjustments of the older nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005004"}
{"pmid": "21005003", "title": "Detection and management of personality and psychosomatic disorders among industrial personnel.", "content": "Detection and management of personality and psychosomatic disorders among industrial personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005003"}
{"pmid": "21005005", "title": "Tick and insect borne diseases.", "content": "Tick and insect borne diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005005"}
{"pmid": "21005006", "title": "Interpretation of medical social work.", "content": "Interpretation of medical social work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005006"}
{"pmid": "21005007", "title": "Influence of environment on the child mind.", "content": "Influence of environment on the child mind.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005007"}
{"pmid": "21005008", "title": "Dental care for mother and child; prevention of dental decay.", "content": "Dental care for mother and child; prevention of dental decay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005008"}
{"pmid": "21005009", "title": "Medical diseases of the kidneys; management and treatment of Bright's disease.", "content": "Medical diseases of the kidneys; management and treatment of Bright's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005009"}
{"pmid": "21005010", "title": "Technique and value of investigating the blood sedimentation rate.", "content": "Technique and value of investigating the blood sedimentation rate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005010"}
{"pmid": "21005011", "title": "Medico-social aspect of convalescence for children.", "content": "Medico-social aspect of convalescence for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005011"}
{"pmid": "21005012", "title": "Severe case of tetanus.", "content": "Severe case of tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005012"}
{"pmid": "21005013", "title": "Early rupture of the membranes; care and nursing management.", "content": "Early rupture of the membranes; care and nursing management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005013"}
{"pmid": "21005014", "title": "Diet in health.", "content": "Diet in health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005014"}
{"pmid": "21005015", "title": "Special tests used in tuberculosis.", "content": "Special tests used in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005015"}
{"pmid": "21005016", "title": "Signs of illness in children.", "content": "Signs of illness in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005016"}
{"pmid": "21005017", "title": "The future of public health nursing.", "content": "The future of public health nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005017"}
{"pmid": "21005018", "title": "State program for the premature infant.", "content": "State program for the premature infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005018"}
{"pmid": "21005019", "title": "SUGGESTED school health policies.", "content": "SUGGESTED school health policies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005019"}
{"pmid": "21005020", "title": "Industrial nurse as health educator.", "content": "Industrial nurse as health educator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005020"}
{"pmid": "21005021", "title": "Improving the education and defining the activities of school health personnel.", "content": "Improving the education and defining the activities of school health personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005021"}
{"pmid": "21005022", "title": "Tachistoscope in visual diagnosis and training.", "content": "Tachistoscope in visual diagnosis and training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005022"}
{"pmid": "21005023", "title": "Tachistoscopic training in the first grade.", "content": "Tachistoscopic training in the first grade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005023"}
{"pmid": "21005025", "title": "Some orientating remarks on tuning-forks and audiometer and on the registration of defects of hearing.", "content": "Some orientating remarks on tuning-forks and audiometer and on the registration of defects of hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005025"}
{"pmid": "21005026", "title": "Nosocomial infections with haemolytic streptococci in an ear department.", "content": "Nosocomial infections with haemolytic streptococci in an ear department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005026"}
{"pmid": "21005029", "title": "The roentgen treatment of vasomotor rhinitis.", "content": "The roentgen treatment of vasomotor rhinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005029"}
{"pmid": "21005030", "title": "Spontaneous postoperative rupture of sigmoid sinus; report of one case.", "content": "Spontaneous postoperative rupture of sigmoid sinus; report of one case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005030"}
{"pmid": "21005031", "title": "Chemotherapy in cases of acute mediastinitis.", "content": "Chemotherapy in cases of acute mediastinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005031"}
{"pmid": "21005024", "title": "The future of optometry.", "content": "The future of optometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005024"}
{"pmid": "21005032", "title": "Nasogenital relationship.", "content": "Nasogenital relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005032"}
{"pmid": "21005033", "title": "Development of the cochlear aqueduct and the round window membrane in the human embryo.", "content": "Development of the cochlear aqueduct and the round window membrane in the human embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005033"}
{"pmid": "21005034", "title": "Early diagnosis and arrest of otosclerosis; clinical and histologic otosclerosis.", "content": "Early diagnosis and arrest of otosclerosis; clinical and histologic otosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005034"}
{"pmid": "21005035", "title": "Receptor apparatus of the vestibulovasomotor reaction.", "content": "Receptor apparatus of the vestibulovasomotor reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005035"}
{"pmid": "21005036", "title": "Aural manifestations of leukemia.", "content": "Aural manifestations of leukemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005036"}
{"pmid": "21005037", "title": "Abscess of the nasal septum complicating acute ethmoiditis.", "content": "Abscess of the nasal septum complicating acute ethmoiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005037"}
{"pmid": "21005038", "title": "A grave reaction to locally applied tetracaine hydrochloride.", "content": "A grave reaction to locally applied tetracaine hydrochloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005038"}
{"pmid": "21005039", "title": "Boeck's sarcoid involving the face and the larynx.", "content": "Boeck's sarcoid involving the face and the larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005039"}
{"pmid": "21005040", "title": "A device for cutting of cartilage isografts.", "content": "A device for cutting of cartilage isografts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005040"}
{"pmid": "21005041", "title": "The paranasal sinuses.", "content": "The paranasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005041"}
{"pmid": "21005042", "title": "Learning through doing.", "content": "Learning through doing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005042"}
{"pmid": "21005046", "title": "Disseminated granuloma venereum.", "content": "Disseminated granuloma venereum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005046"}
{"pmid": "21005047", "title": "Intermittent fever with lesions simulating those of Hodgkin's disease; a case report.", "content": "Intermittent fever with lesions simulating those of Hodgkin's disease; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005047"}
{"pmid": "21005048", "title": "Penicillin resistance of Staphylococcus aureus and its clinical implications.", "content": "Penicillin resistance of Staphylococcus aureus and its clinical implications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005048"}
{"pmid": "21005049", "title": "Determination of bromsulphalein in normal, turbid, hemolyzed, or icteric serums.", "content": "Determination of bromsulphalein in normal, turbid, hemolyzed, or icteric serums.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005049"}
{"pmid": "21005050", "title": "Sarcoma of prostate; a report of one case of rhabdomyosarcoma of the prostate.", "content": "Sarcoma of prostate; a report of one case of rhabdomyosarcoma of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005050"}
{"pmid": "21005051", "title": "Erythroblastosis fetalis unrelated to the Rh factor; report of nine cases suggesting isoimmunization of group O mothers by A children.", "content": "Erythroblastosis fetalis unrelated to the Rh factor; report of nine cases suggesting isoimmunization of group O mothers by A children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005051"}
{"pmid": "21005052", "title": "Rh heterozygous Mendelian transmission in a large family; a case report.", "content": "Rh heterozygous Mendelian transmission in a large family; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005052"}
{"pmid": "21005053", "title": "Tuberculoid reaction in a retroperitoneal neurocytoma.", "content": "Tuberculoid reaction in a retroperitoneal neurocytoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005053"}
{"pmid": "21005054", "title": "A screening test for identification of allergic states.", "content": "A screening test for identification of allergic states.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005054"}
{"pmid": "21005055", "title": "Ammonia poisoning and hemolytic anemia with bone marrow heterotopia.", "content": "Ammonia poisoning and hemolytic anemia with bone marrow heterotopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005055"}
{"pmid": "21005058", "title": "Results of providing a liberally adequate diet to children in an institution; acceptance of foods and changes in the adequacy of diets consumed.", "content": "Results of providing a liberally adequate diet to children in an institution; acceptance of foods and changes in the adequacy of diets consumed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005058"}
{"pmid": "21005059", "title": "Results of providing a liberally adequate diet to children in an institution; growth in weight and height.", "content": "Results of providing a liberally adequate diet to children in an institution; growth in weight and height.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005059"}
{"pmid": "21005060", "title": "Results of providing a liberally adequate diet to children in an institution; blood and urinary excretion studies before and after dietary improvement.", "content": "Results of providing a liberally adequate diet to children in an institution; blood and urinary excretion studies before and after dietary improvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005060"}
{"pmid": "21005061", "title": "The crying of newly born babies; the early period at home.", "content": "The crying of newly born babies; the early period at home.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005061"}
{"pmid": "21005062", "title": "Penicillin therapy of Staphylococcus aureus hemolyticus infection in an allergic infant.", "content": "Penicillin therapy of Staphylococcus aureus hemolyticus infection in an allergic infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005062"}
{"pmid": "21005063", "title": "Penicillin therapy in ratbite fever.", "content": "Penicillin therapy in ratbite fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005063"}
{"pmid": "21005064", "title": "Penicillin locally in the eyes of newborn infants to prevent ophthalmia neonatorum.", "content": "Penicillin locally in the eyes of newborn infants to prevent ophthalmia neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005064"}
{"pmid": "21005065", "title": "Unusual fulminating generalized staphylococcus infections treated with penicillin.", "content": "Unusual fulminating generalized staphylococcus infections treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005065"}
{"pmid": "21005066", "title": "The prognosis in acute glomerulonephritis in children.", "content": "The prognosis in acute glomerulonephritis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005066"}
{"pmid": "21005067", "title": "Surgical treatment of congenital atresia of the esophagus; with a report of four cases.", "content": "Surgical treatment of congenital atresia of the esophagus; with a report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005067"}
{"pmid": "21005068", "title": "Erythema exudativum sultiforme (Hebra) bullous type.", "content": "Erythema exudativum sultiforme (Hebra) bullous type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005068"}
{"pmid": "21005069", "title": "Pneumonia due to Streptococcus viridans; review of literature and case report of an infant.", "content": "Pneumonia due to Streptococcus viridans; review of literature and case report of an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005069"}
{"pmid": "21005070", "title": "Congenital megacolon; treatment with mecholyl bromide.", "content": "Congenital megacolon; treatment with mecholyl bromide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005070"}
{"pmid": "21005071", "title": "Subcutaneous administration of sodium sulfadiazine.", "content": "Subcutaneous administration of sodium sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005071"}
{"pmid": "21005072", "title": "Comments on the Maryland plan for medical care as outlined by Dr. Dean Roberts in the October issue of the Journal of Pediatrics.", "content": "Comments on the Maryland plan for medical care as outlined by Dr. Dean Roberts in the October issue of the Journal of Pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005072"}
{"pmid": "21005073", "title": "The pharmacist as a public health educator.", "content": "The pharmacist as a public health educator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005073"}
{"pmid": "21005074", "title": "STREPTOMYCIN-PROMIN therapy.", "content": "STREPTOMYCIN-PROMIN therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005074"}
{"pmid": "21005075", "title": "CHEMOTHERAPY of leprosy.", "content": "CHEMOTHERAPY of leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005075"}
{"pmid": "21005076", "title": "ANTIBIOTICS in urinary tract infection.", "content": "ANTIBIOTICS in urinary tract infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005076"}
{"pmid": "21005077", "title": "BACITRACIN; new effective antibiotic agent.", "content": "BACITRACIN; new effective antibiotic agent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005077"}
{"pmid": "21005078", "title": "PROTEINS and amino acids.", "content": "PROTEINS and amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005078"}
{"pmid": "21005079", "title": "CONDITIONS for sterilizing dressings.", "content": "CONDITIONS for sterilizing dressings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005079"}
{"pmid": "21005080", "title": "Thiouracil.", "content": "Thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005080"}
{"pmid": "21005082", "title": "Pharmaceutical chemistry; whence and whither?", "content": "Pharmaceutical chemistry; whence and whither?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005082"}
{"pmid": "21005081", "title": "Electron microscopy.", "content": "Electron microscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005081"}
{"pmid": "21005083", "title": "The assay of alkaloidal galenicals using the chromatograph; preparations of belladonna, stramonium and nux vomica.", "content": "The assay of alkaloidal galenicals using the chromatograph; preparations of belladonna, stramonium and nux vomica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005083"}
{"pmid": "21005084", "title": "The assay of alkaloidal galenicals using the chromatograph; liquid extract of ergot B.P. and extract of ergot B.P.C.", "content": "The assay of alkaloidal galenicals using the chromatograph; liquid extract of ergot B.P. and extract of ergot B.P.C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005084"}
{"pmid": "21005085", "title": "Increased alkaloidal contents of induced polyploids of Datura, Atropa and Hyoscyamus; Datura species.", "content": "Increased alkaloidal contents of induced polyploids of Datura, Atropa and Hyoscyamus; Datura species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005085"}
{"pmid": "21005086", "title": "Increased alkaloidal contents of induced polyploids of Datura, Atropa and Hyoscyamus; Atropa and Hyoscyamus species.", "content": "Increased alkaloidal contents of induced polyploids of Datura, Atropa and Hyoscyamus; Atropa and Hyoscyamus species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005086"}
{"pmid": "21005087", "title": "Notes on some tests for acetone and ethyl alcohol, with special reference to methyl alcohol.", "content": "Notes on some tests for acetone and ethyl alcohol, with special reference to methyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005087"}
{"pmid": "21005088", "title": "The limits of accuracy of the determination of alcohol by the method of the British Pharmacopoeia.", "content": "The limits of accuracy of the determination of alcohol by the method of the British Pharmacopoeia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005088"}
{"pmid": "21005089", "title": "Cardamom: further numerical studies of its sclerenchymatous layer.", "content": "Cardamom: further numerical studies of its sclerenchymatous layer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005089"}
{"pmid": "21005090", "title": "Cardamom: structural and numerical features of the testa; including their combined application for diagnostic purposes.", "content": "Cardamom: structural and numerical features of the testa; including their combined application for diagnostic purposes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005090"}
{"pmid": "21005091", "title": "A comparison of methods of analysis of euflavine gauze with observations on the effect of sterilisation.", "content": "A comparison of methods of analysis of euflavine gauze with observations on the effect of sterilisation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005091"}
{"pmid": "21005092", "title": "The determination of lipase in pancreatin together with a report on commercial pancreatins.", "content": "The determination of lipase in pancreatin together with a report on commercial pancreatins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005092"}
{"pmid": "21005093", "title": "A polarographic study of alkaloids.", "content": "A polarographic study of alkaloids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005093"}
{"pmid": "21005094", "title": "The chemical testing of antacids.", "content": "The chemical testing of antacids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005094"}
{"pmid": "21005097", "title": "An improved solution of adrenaline prepared from adrenaline tartrate.", "content": "An improved solution of adrenaline prepared from adrenaline tartrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005097"}
{"pmid": "21005095", "title": "The fluorimetric estimation of vitamin B1 in tablets and other pharmaceutical products.", "content": "The fluorimetric estimation of vitamin B1 in tablets and other pharmaceutical products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005095"}
{"pmid": "21005096", "title": "The stability of adrenaline solutions; solutions of adrenaline tartrate.", "content": "The stability of adrenaline solutions; solutions of adrenaline tartrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005096"}
{"pmid": "21005098", "title": "BLOOD pressure; physiologic aspects of blood pressure and diagnosis of hypertension.", "content": "BLOOD pressure; physiologic aspects of blood pressure and diagnosis of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005098"}
{"pmid": "21005099", "title": "The effects of caffeine on oxygen consumption and cell division in the fertilized egg of the sea urchin, Arbacia punctulata.", "content": "The effects of caffeine on oxygen consumption and cell division in the fertilized egg of the sea urchin, Arbacia punctulata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005099"}
{"pmid": "21005100", "title": "Water relations in the cell; the chloroplasts of Nitella and of Spirogyra.", "content": "Water relations in the cell; the chloroplasts of Nitella and of Spirogyra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005100"}
{"pmid": "21005101", "title": "The action spectrum of sensitization to heat with ultraviolet light.", "content": "The action spectrum of sensitization to heat with ultraviolet light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005101"}
{"pmid": "21005102", "title": "The paracrystalline state of the rat red cell.", "content": "The paracrystalline state of the rat red cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005102"}
{"pmid": "21005103", "title": "On the nature of forces operating in blood clotting; the participation of electrostatic attraction.", "content": "On the nature of forces operating in blood clotting; the participation of electrostatic attraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005103"}
{"pmid": "21005104", "title": "On the nature of forces operating in blood clotting; the clotting of fibrinogen as a two-step reaction.", "content": "On the nature of forces operating in blood clotting; the clotting of fibrinogen as a two-step reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005104"}
{"pmid": "21005105", "title": "The dependence of behavior disorder in the rat upon blood composition; audiogenic-seizure as a function of blood composition.", "content": "The dependence of behavior disorder in the rat upon blood composition; audiogenic-seizure as a function of blood composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005105"}
{"pmid": "21005106", "title": "The dependence of behavior disorder in the rat upon blood composition; maze performance, activity, and wildness as functions of blood composition.", "content": "The dependence of behavior disorder in the rat upon blood composition; maze performance, activity, and wildness as functions of blood composition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005106"}
{"pmid": "21005108", "title": "The night habits of the dragonfly, Ajax junius Dru.", "content": "The night habits of the dragonfly, Ajax junius Dru.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005108"}
{"pmid": "21005109", "title": "A type of psychopathy in the domestic pigeon.", "content": "A type of psychopathy in the domestic pigeon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005109"}
{"pmid": "21005107", "title": "The dependence of behavior disorder in the rat upon blood composition; behavior disorder as a function of repeated adrenalin injections.", "content": "The dependence of behavior disorder in the rat upon blood composition; behavior disorder as a function of repeated adrenalin injections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005107"}
{"pmid": "21005111", "title": "The role of motivational factors in insightful problem-solving.", "content": "The role of motivational factors in insightful problem-solving.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005111"}
{"pmid": "21005112", "title": "Four years of a college adjustment clinic; organization of clinic and problems of counselees.", "content": "Four years of a college adjustment clinic; organization of clinic and problems of counselees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005112"}
{"pmid": "21005110", "title": "Caste in colonies of Polistes wasps.", "content": "Caste in colonies of Polistes wasps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005110"}
{"pmid": "21005113", "title": "Four years of a college adjustment clinic; characteristics of counselees.", "content": "Four years of a college adjustment clinic; characteristics of counselees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005113"}
{"pmid": "21005115", "title": "The validity of the amplified multiple choice Rorschach as a screening device.", "content": "The validity of the amplified multiple choice Rorschach as a screening device.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005115"}
{"pmid": "21005116", "title": "Sidelights on the use of intelligence tests.", "content": "Sidelights on the use of intelligence tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005116"}
{"pmid": "21005114", "title": "Some contributions of nondirective methods to college counseling.", "content": "Some contributions of nondirective methods to college counseling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005114"}
{"pmid": "21005118", "title": "Functions of a psychologist in a residential school for the deaf.", "content": "Functions of a psychologist in a residential school for the deaf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005118"}
{"pmid": "21005117", "title": "The use of certain standardized tests in the selection of inspectors in an aircraft factory.", "content": "The use of certain standardized tests in the selection of inspectors in an aircraft factory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005117"}
{"pmid": "21005120", "title": "Training in clinical psychology; a note on trends.", "content": "Training in clinical psychology; a note on trends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005120"}
{"pmid": "21005123", "title": "ARMY General Classification Test.", "content": "ARMY General Classification Test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005123"}
{"pmid": "21005122", "title": "Psychology and the war.", "content": "Psychology and the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005122"}
{"pmid": "21005121", "title": "Graduate internship training in psychology.", "content": "Graduate internship training in psychology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005121"}
{"pmid": "21005119", "title": "A note on psychotherapy as a function of psychologists.", "content": "A note on psychotherapy as a function of psychologists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005119"}
{"pmid": "21005124", "title": "PSYCHOLOGICAL test construction and research in the Bureau of Naval Personnel; measurement of achievement in Navy training.", "content": "PSYCHOLOGICAL test construction and research in the Bureau of Naval Personnel; measurement of achievement in Navy training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005124"}
{"pmid": "21005127", "title": "A study of Shigella by means of bacteriophage.", "content": "A study of Shigella by means of bacteriophage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005127"}
{"pmid": "21005125", "title": "A speech pathology program for Naval hospitals.", "content": "A speech pathology program for Naval hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005125"}
{"pmid": "21005126", "title": "A social therapy program for neuropsychiatry in a general hospital.", "content": "A social therapy program for neuropsychiatry in a general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005126"}
{"pmid": "21005128", "title": "Surveys of the nutrition of populations; the vitamin C nutrition of a rural population in middle, Tennessee.", "content": "Surveys of the nutrition of populations; the vitamin C nutrition of a rural population in middle, Tennessee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005128"}
{"pmid": "21005130", "title": "The question of the transmission of poliomyelitis in rhesus monkeys by accidental laboratory infection.", "content": "The question of the transmission of poliomyelitis in rhesus monkeys by accidental laboratory infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005130"}
{"pmid": "21005134", "title": "Studies on Plasmodium gallinaceum Brumpt; the incidence and course of the infection in young chicks following the subcutaneous inoculation of pooled sporozoites.", "content": "Studies on Plasmodium gallinaceum Brumpt; the incidence and course of the infection in young chicks following the subcutaneous inoculation of pooled sporozoites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005134"}
{"pmid": "21005131", "title": "An evaluation of various measures of anopheles larva density.", "content": "An evaluation of various measures of anopheles larva density.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005131"}
{"pmid": "21005129", "title": "A survey of intestinal parasites in natives in Dutch New Guinea.", "content": "A survey of intestinal parasites in natives in Dutch New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005129"}
{"pmid": "21005132", "title": "Epidemiologic studies of encephalitis in the San Joaquin Valley of California, 1943, with the isolation of viruses from mosquitoes.", "content": "Epidemiologic studies of encephalitis in the San Joaquin Valley of California, 1943, with the isolation of viruses from mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005132"}
{"pmid": "21005133", "title": "Immunization against influenza with observations during an epidemic of influenza A one year after vaccination.", "content": "Immunization against influenza with observations during an epidemic of influenza A one year after vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005133"}
{"pmid": "21005137", "title": "The tuberculostatic action of streptothricin and streptomycin with special reference to the action of streptomycin on the chorioallantoic membrane of the chick embryo.", "content": "The tuberculostatic action of streptothricin and streptomycin with special reference to the action of streptomycin on the chorioallantoic membrane of the chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005137"}
{"pmid": "21005138", "title": "Epdiemiological significance of seasonal variations in rodent-ectoparasite distribution.", "content": "Epdiemiological significance of seasonal variations in rodent-ectoparasite distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005138"}
{"pmid": "21005139", "title": "The age factor in disabling morbidity, 1940-44; experience in a public utility company.", "content": "The age factor in disabling morbidity, 1940-44; experience in a public utility company.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005139"}
{"pmid": "21005140", "title": "Roentgenographic interpretation of acute hematogenous osteomyelitis treated with penicillin.", "content": "Roentgenographic interpretation of acute hematogenous osteomyelitis treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005140"}
{"pmid": "21005141", "title": "Studies on roentgen death in mice.", "content": "Studies on roentgen death in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005141"}
{"pmid": "21005142", "title": "Studies on roentgen death in mice; body weight and sensitivity.", "content": "Studies on roentgen death in mice; body weight and sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005142"}
{"pmid": "21005144", "title": "Miniature chest fluorography with control study.", "content": "Miniature chest fluorography with control study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005144"}
{"pmid": "21005143", "title": "Pneumoroentgenography with oxygen in the diagnosis of internal derangements of the knee joint.", "content": "Pneumoroentgenography with oxygen in the diagnosis of internal derangements of the knee joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005143"}
{"pmid": "21005145", "title": "Miliary carcinosis of the lungs secondary to primary cancer of the gastrointestinal tract.", "content": "Miliary carcinosis of the lungs secondary to primary cancer of the gastrointestinal tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005145"}
{"pmid": "21005146", "title": "Diaphragmatic hernia and dilated esophageal ampulla; their clinical and diagnostic significance.", "content": "Diaphragmatic hernia and dilated esophageal ampulla; their clinical and diagnostic significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005146"}
{"pmid": "21005147", "title": "Chronic nonspecific regional enteritis.", "content": "Chronic nonspecific regional enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005147"}
{"pmid": "21005148", "title": "Roentgen examination in congenital intestinal obstructive defects in infants; its aid in planning suitable surgical approach and procedures for their correction.", "content": "Roentgen examination in congenital intestinal obstructive defects in infants; its aid in planning suitable surgical approach and procedures for their correction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005148"}
{"pmid": "21005149", "title": "The so-called fifth and sixth cerebral ventricle; a clinical and roentgenographic study and case report.", "content": "The so-called fifth and sixth cerebral ventricle; a clinical and roentgenographic study and case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005149"}
{"pmid": "21005150", "title": "Benign giant cell tumor of the spine; report of a case occurring in the cervical spine.", "content": "Benign giant cell tumor of the spine; report of a case occurring in the cervical spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005150"}
{"pmid": "21005151", "title": "Hypertrophic osteoarthropathy; case report.", "content": "Hypertrophic osteoarthropathy; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005151"}
{"pmid": "21005152", "title": "BONE changes in electric current injuries.", "content": "BONE changes in electric current injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005152"}
{"pmid": "21005153", "title": "Fifty years of x-ray production and measurement in medical radiology.", "content": "Fifty years of x-ray production and measurement in medical radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005153"}
{"pmid": "21005154", "title": "Pneumoconiosis in radiator and boiler finishers.", "content": "Pneumoconiosis in radiator and boiler finishers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005154"}
{"pmid": "21005155", "title": "The design of filters to produce flat x-ray isodose curves at a given depth.", "content": "The design of filters to produce flat x-ray isodose curves at a given depth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005155"}
{"pmid": "21005156", "title": "Investigation of free gas in the peritoneal cavity.", "content": "Investigation of free gas in the peritoneal cavity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005156"}
{"pmid": "21005157", "title": "Radiological appearances of the chest following partial asphyxiation by a smoke screen.", "content": "Radiological appearances of the chest following partial asphyxiation by a smoke screen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005157"}
{"pmid": "21005158", "title": "A new method of primary screening by x-ray examination.", "content": "A new method of primary screening by x-ray examination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005158"}
{"pmid": "21005159", "title": "Note on a function in the mathematical theory of integral dose.", "content": "Note on a function in the mathematical theory of integral dose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005159"}
{"pmid": "21005160", "title": "Importance of anatomical study in radiographic positioning.", "content": "Importance of anatomical study in radiographic positioning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005160"}
{"pmid": "21005161", "title": "Radiography of the mandible suitable for cases with multiple injuries.", "content": "Radiography of the mandible suitable for cases with multiple injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005161"}
{"pmid": "21005170", "title": "Hemorrhage as the most frequent cause of maternal death; an analysis of the puerperal deaths in Brooklyn, 1944.", "content": "Hemorrhage as the most frequent cause of maternal death; an analysis of the puerperal deaths in Brooklyn, 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005170"}
{"pmid": "21005173", "title": "Simplification of split skin grafting; gum acacia technic.", "content": "Simplification of split skin grafting; gum acacia technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005173"}
{"pmid": "21005174", "title": "Control of the thyroid storm.", "content": "Control of the thyroid storm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005174"}
{"pmid": "21005172", "title": "Surgical management of femoral vein thrombosis.", "content": "Surgical management of femoral vein thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005172"}
{"pmid": "21005175", "title": "Experimental transmission of lymphogranuloma venereum virus through the placenta.", "content": "Experimental transmission of lymphogranuloma venereum virus through the placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005175"}
{"pmid": "21005171", "title": "Intravenous obstetrical anesthesia; preliminary report.", "content": "Intravenous obstetrical anesthesia; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005171"}
{"pmid": "21005176", "title": "The use of thrombin (topical) in transurethral resection of the prostate.", "content": "The use of thrombin (topical) in transurethral resection of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005176"}
{"pmid": "21005177", "title": "Urinary stress incontinence in the female; a combined gyno-urological approach to its correction.", "content": "Urinary stress incontinence in the female; a combined gyno-urological approach to its correction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005177"}
{"pmid": "21005178", "title": "Phthalylsulfathiazole-sulfathidine; a clinical evaluation in 122 patients with proctologic and related conditions.", "content": "Phthalylsulfathiazole-sulfathidine; a clinical evaluation in 122 patients with proctologic and related conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005178"}
{"pmid": "21005179", "title": "A method of treatment for pilonidal sinus.", "content": "A method of treatment for pilonidal sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005179"}
{"pmid": "21005180", "title": "Refrigeration anesthesia.", "content": "Refrigeration anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005180"}
{"pmid": "21005181", "title": "Treatment of intertrochanteric fractures of the femur.", "content": "Treatment of intertrochanteric fractures of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005181"}
{"pmid": "21005182", "title": "Newer postoperative trends.", "content": "Newer postoperative trends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005182"}
{"pmid": "21005183", "title": "Bicipital tendovaginitis.", "content": "Bicipital tendovaginitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005183"}
{"pmid": "21005184", "title": "Acute suppurative appendicitis with abscess formation and subsequent perforation of the anterior abdominal wall.", "content": "Acute suppurative appendicitis with abscess formation and subsequent perforation of the anterior abdominal wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005184"}
{"pmid": "21005185", "title": "Polyps of the appendix.", "content": "Polyps of the appendix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005185"}
{"pmid": "21005186", "title": "Benign tumors of the duodenum.", "content": "Benign tumors of the duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005186"}
{"pmid": "21005187", "title": "Mixed bacterial gangrene of an extremity treated with penicillin and sulfadiazine.", "content": "Mixed bacterial gangrene of an extremity treated with penicillin and sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005187"}
{"pmid": "21005188", "title": "Surgical aspects of certain blood dyscrasias.", "content": "Surgical aspects of certain blood dyscrasias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005188"}
{"pmid": "21005189", "title": "Primary repair of the parotid duct.", "content": "Primary repair of the parotid duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005189"}
{"pmid": "21005190", "title": "The use of blood plasma for filling the pleural space following total pneumonectomy.", "content": "The use of blood plasma for filling the pleural space following total pneumonectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005190"}
{"pmid": "21005191", "title": "Chronic leptomeningeal thickening following treatment of meningitis with sulfadrugs.", "content": "Chronic leptomeningeal thickening following treatment of meningitis with sulfadrugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005191"}
{"pmid": "21005192", "title": "Radical resections of advanced intra-abdominal cancer; summary of results in 100 patients.", "content": "Radical resections of advanced intra-abdominal cancer; summary of results in 100 patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005192"}
{"pmid": "21005193", "title": "Surgical relief of tremor at rest.", "content": "Surgical relief of tremor at rest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005193"}
{"pmid": "21005194", "title": "Transthoracic esophagogastrostomy for benign strictures of the lower esophagus.", "content": "Transthoracic esophagogastrostomy for benign strictures of the lower esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005194"}
{"pmid": "21005195", "title": "The use of penicillin in the treatment of acute hematogenous osteomyelitis in children.", "content": "The use of penicillin in the treatment of acute hematogenous osteomyelitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005195"}
{"pmid": "21005196", "title": "Blood iodine studies; the relation of the basal metabolic rate to the blood iodine in thyroid disease.", "content": "Blood iodine studies; the relation of the basal metabolic rate to the blood iodine in thyroid disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005196"}
{"pmid": "21005197", "title": "Vagotomy for gastroduodenal ulcer.", "content": "Vagotomy for gastroduodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005197"}
{"pmid": "21005198", "title": "Blood pressure of renal and of early and late neurogenic hypertension dogs after low cervical cord section.", "content": "Blood pressure of renal and of early and late neurogenic hypertension dogs after low cervical cord section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005198"}
{"pmid": "21005199", "title": "Cutis grafts; clinical and experimental studies on their use as a reinforcing patch in the repair of large ventral and incisional herniae.", "content": "Cutis grafts; clinical and experimental studies on their use as a reinforcing patch in the repair of large ventral and incisional herniae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005199"}
{"pmid": "21005200", "title": "The pathogenesis of localized fibrous lesions in the metaphyses of long bones.", "content": "The pathogenesis of localized fibrous lesions in the metaphyses of long bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005200"}
{"pmid": "21005201", "title": "Bilateral adrenalectomy in prostatic cancer.", "content": "Bilateral adrenalectomy in prostatic cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005201"}
{"pmid": "21005202", "title": "Subtotal replacement of the skin of the face for actinodermatitis due to roentgenotherapy; with multiple areas of squamous cell carcinoma.", "content": "Subtotal replacement of the skin of the face for actinodermatitis due to roentgenotherapy; with multiple areas of squamous cell carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005202"}
{"pmid": "21005203", "title": "Congenital cataracts following rubella in pregnancy.", "content": "Congenital cataracts following rubella in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005203"}
{"pmid": "21005204", "title": "Headache from lesions of scalp nerves.", "content": "Headache from lesions of scalp nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005204"}
{"pmid": "21005205", "title": "Osteomyelitis of the petrous pyramid of the temporal bone.", "content": "Osteomyelitis of the petrous pyramid of the temporal bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005205"}
{"pmid": "21005206", "title": "The present status of ethylene-oxygen anesthesia.", "content": "The present status of ethylene-oxygen anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005206"}
{"pmid": "21005207", "title": "Acoustic trauma.", "content": "Acoustic trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005207"}
{"pmid": "21005208", "title": "Resection of the left lobe of the liver in a patient with four separate carcinomas.", "content": "Resection of the left lobe of the liver in a patient with four separate carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005208"}
{"pmid": "21005209", "title": "The etiology and treatment of polycythemia rubra vera.", "content": "The etiology and treatment of polycythemia rubra vera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005209"}
{"pmid": "21005211", "title": "Traumatic rupture of the spleen.", "content": "Traumatic rupture of the spleen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005211"}
{"pmid": "21005210", "title": "Principles and practice of penicillin therapy in diseases of the nervous system.", "content": "Principles and practice of penicillin therapy in diseases of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005210"}
{"pmid": "21005212", "title": "Acute hypertension with sodium pentothal anesthesia in neurologic surgery.", "content": "Acute hypertension with sodium pentothal anesthesia in neurologic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005212"}
{"pmid": "21005213", "title": "Gelatin sponge; surgical investigation of a new matrix used in conjunction with thrombin in hemostasis.", "content": "Gelatin sponge; surgical investigation of a new matrix used in conjunction with thrombin in hemostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005213"}
{"pmid": "21005215", "title": "Penicillin in the treatment of chronic osteomyelitis; a preliminary report.", "content": "Penicillin in the treatment of chronic osteomyelitis; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005215"}
{"pmid": "21005214", "title": "Skin bacteria; their role in contamination and infection of wounds.", "content": "Skin bacteria; their role in contamination and infection of wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005214"}
{"pmid": "21005216", "title": "Post-traumatic renal injury; summary of experimental observations.", "content": "Post-traumatic renal injury; summary of experimental observations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005216"}
{"pmid": "21005218", "title": "Surgical therapy of the patent ductus arteriosus; report of 5 cases.", "content": "Surgical therapy of the patent ductus arteriosus; report of 5 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005218"}
{"pmid": "21005217", "title": "Chronic ulcerative colitis with generalized peritonitis and recovery; treatment with penicillin and sulfadiazine.", "content": "Chronic ulcerative colitis with generalized peritonitis and recovery; treatment with penicillin and sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005217"}
{"pmid": "21005219", "title": "Ulcerating lesions of the gastroenteric stoma.", "content": "Ulcerating lesions of the gastroenteric stoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005219"}
{"pmid": "21005220", "title": "Leiomyosarcoma of the uterus with metastasis to the femur; report of a case and review of the literature.", "content": "Leiomyosarcoma of the uterus with metastasis to the femur; report of a case and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005220"}
{"pmid": "21005229", "title": "Anesthesia problems in thoracic surgery.", "content": "Anesthesia problems in thoracic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005229"}
{"pmid": "21005230", "title": "Cyclopropane in general surgery.", "content": "Cyclopropane in general surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005230"}
{"pmid": "21005231", "title": "Pentothal sodium or balanced anesthesia for tonsillectomy operation.", "content": "Pentothal sodium or balanced anesthesia for tonsillectomy operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005231"}
{"pmid": "21005223", "title": "Anesthesia service in a Canadian veteran's hospital.*", "content": "Anesthesia service in a Canadian veteran's hospital.*", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005223"}
{"pmid": "21005221", "title": "Anaesthetic record card.", "content": "Anaesthetic record card.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005221"}
{"pmid": "21005232", "title": "For amputation of thigh; ice anesthesia.", "content": "For amputation of thigh; ice anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005232"}
{"pmid": "21005228", "title": "A slotted endotracheal tube.", "content": "A slotted endotracheal tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005228"}
{"pmid": "21005222", "title": "Intravenous anesthesia in the tropics.", "content": "Intravenous anesthesia in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005222"}
{"pmid": "21005227", "title": "Selective sensory (posterior) spinal nerve root block; a preliminary report.", "content": "Selective sensory (posterior) spinal nerve root block; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005227"}
{"pmid": "21005224", "title": "Refrigeration anesthesia for amputations.", "content": "Refrigeration anesthesia for amputations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005224"}
{"pmid": "21005234", "title": "Solid tumors of the ovary.", "content": "Solid tumors of the ovary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005234"}
{"pmid": "21005225", "title": "Curare-a complement to anesthesia.*", "content": "Curare-a complement to anesthesia.*", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005225"}
{"pmid": "21005233", "title": "Ten years' experience with the surgical treatment of pulmonary tuberculosis.", "content": "Ten years' experience with the surgical treatment of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005233"}
{"pmid": "21005226", "title": "Specialized anesthesia for tonsillectomy.", "content": "Specialized anesthesia for tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005226"}
{"pmid": "21005235", "title": "A new operative technic for cysts of the lung and for chronic spontaneous pneumothorax.", "content": "A new operative technic for cysts of the lung and for chronic spontaneous pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005235"}
{"pmid": "21005236", "title": "Sano tissue glue skin grafting.", "content": "Sano tissue glue skin grafting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005236"}
{"pmid": "21005237", "title": "Local infiltration of procaine hydrochloride solution combined with intravenous administration of pentothal sodium.", "content": "Local infiltration of procaine hydrochloride solution combined with intravenous administration of pentothal sodium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005237"}
{"pmid": "21005239", "title": "The newer developments in shock and refrigeration.", "content": "The newer developments in shock and refrigeration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005239"}
{"pmid": "21005241", "title": "Management of swallowed sharp foreign bodies.", "content": "Management of swallowed sharp foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005241"}
{"pmid": "21005238", "title": "Supravaginal and complete hysterectomies; an analysis of indications, results and dangers.", "content": "Supravaginal and complete hysterectomies; an analysis of indications, results and dangers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005238"}
{"pmid": "21005240", "title": "A method of inguinal herniorrhaphy.", "content": "A method of inguinal herniorrhaphy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005240"}
{"pmid": "21005283", "title": "An experimental evaluation of sulfasuxidine and sulfathalidine in surgery of the colon.", "content": "An experimental evaluation of sulfasuxidine and sulfathalidine in surgery of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005283"}
{"pmid": "21005284", "title": "Surgery of the colon in the forward battle area.", "content": "Surgery of the colon in the forward battle area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005284"}
{"pmid": "21005286", "title": "Observations on large bowel perforations.", "content": "Observations on large bowel perforations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005286"}
{"pmid": "21005285", "title": "Operative results of surgery of the colon for neoplastic disease.", "content": "Operative results of surgery of the colon for neoplastic disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005285"}
{"pmid": "21005289", "title": "Closure of duodenal fistula.", "content": "Closure of duodenal fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005289"}
{"pmid": "21005288", "title": "An intestinal spur-crushing clamp.", "content": "An intestinal spur-crushing clamp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005288"}
{"pmid": "21005287", "title": "Small bowel stricture following irradiation therapy for carcinoma of the fundus uteri.", "content": "Small bowel stricture following irradiation therapy for carcinoma of the fundus uteri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005287"}
{"pmid": "21005291", "title": "Subtotal and palliative gastrectomy for chronic gastric ulcer.", "content": "Subtotal and palliative gastrectomy for chronic gastric ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005291"}
{"pmid": "21005290", "title": "A method of implanting the pancreatic duct into the jejunum in the Whipple operation for carcinoma of the pancreas; case report.", "content": "A method of implanting the pancreatic duct into the jejunum in the Whipple operation for carcinoma of the pancreas; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005290"}
{"pmid": "21005292", "title": "The hypochloremic state in surgical patients.", "content": "The hypochloremic state in surgical patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005292"}
{"pmid": "21005293", "title": "New techniques for parenteral fluid and drug administration; muscular intubation.", "content": "New techniques for parenteral fluid and drug administration; muscular intubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005293"}
{"pmid": "21005294", "title": "Studies on the mechanism of citrate intoxication in massive transfusions of whole blood.", "content": "Studies on the mechanism of citrate intoxication in massive transfusions of whole blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005294"}
{"pmid": "21005295", "title": "A modification of the Gius-Racely portable suction apparatus.", "content": "A modification of the Gius-Racely portable suction apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005295"}
{"pmid": "21005296", "title": "Spicular foreign bodies in esophagus; report of 3 unusual cases.", "content": "Spicular foreign bodies in esophagus; report of 3 unusual cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005296"}
{"pmid": "21005297", "title": "The surgical problem of cancer in lymph nodes.", "content": "The surgical problem of cancer in lymph nodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005297"}
{"pmid": "21005298", "title": "Effect of total thyroidectomy on experimental production of peptic ulcer.", "content": "Effect of total thyroidectomy on experimental production of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005298"}
{"pmid": "21005299", "title": "The healing of arteries and the relationship to secondary hemorrhage.", "content": "The healing of arteries and the relationship to secondary hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005299"}
{"pmid": "21005300", "title": "Studies in experimental vascular surgery.", "content": "Studies in experimental vascular surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005300"}
{"pmid": "21005302", "title": "Multiple arteriovenous aneurysms; report of a case of 4 arteriovenous aneurysms in 1 individual.", "content": "Multiple arteriovenous aneurysms; report of a case of 4 arteriovenous aneurysms in 1 individual.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005302"}
{"pmid": "21005301", "title": "Suture of the popliteal artery; a report of 3 cases.", "content": "Suture of the popliteal artery; a report of 3 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005301"}
{"pmid": "21005303", "title": "Skin transposition in incisional defects; a modification of the Z plastic for primary skin closure following extensive breast surgery.", "content": "Skin transposition in incisional defects; a modification of the Z plastic for primary skin closure following extensive breast surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005303"}
{"pmid": "21005304", "title": "The use of cotton sutures in lower abdominal surgery.", "content": "The use of cotton sutures in lower abdominal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005304"}
{"pmid": "21005305", "title": "A new instrument and a simplified technique for the cure of ingrown nails.", "content": "A new instrument and a simplified technique for the cure of ingrown nails.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005305"}
{"pmid": "21005306", "title": "Segmental resection of lesions occurring in the left half of the colon with primary end-to-end aseptic anastomosis; report based on 50 cases.", "content": "Segmental resection of lesions occurring in the left half of the colon with primary end-to-end aseptic anastomosis; report based on 50 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005306"}
{"pmid": "21005307", "title": "Penicillin therapy in abdominal surgery; the results of prophylactic and therapeutic use in 50 cases.", "content": "Penicillin therapy in abdominal surgery; the results of prophylactic and therapeutic use in 50 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005307"}
{"pmid": "21005308", "title": "War surgery of the abdomen.", "content": "War surgery of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005308"}
{"pmid": "21005309", "title": "Gunshot wounds of the spine; observations from an evacuation hospital.", "content": "Gunshot wounds of the spine; observations from an evacuation hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005309"}
{"pmid": "21005310", "title": "Resection of the lung in pulmonary suppurative diseases; factors contributing to its progress.", "content": "Resection of the lung in pulmonary suppurative diseases; factors contributing to its progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005310"}
{"pmid": "21005311", "title": "Granulosa cell tumor of the ovary; a clinical and pathologic review of 62 cases.", "content": "Granulosa cell tumor of the ovary; a clinical and pathologic review of 62 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005311"}
{"pmid": "21005312", "title": "Congenital malformations of the first thoracic rib; a cause of brachial neuralgia which simulates the cervical rib syndrome.", "content": "Congenital malformations of the first thoracic rib; a cause of brachial neuralgia which simulates the cervical rib syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005312"}
{"pmid": "21005314", "title": "Juxtacervicovesical fistula.", "content": "Juxtacervicovesical fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005314"}
{"pmid": "21005313", "title": "Galvanic tetanus and galvanic tetanus ratio in electrodiagnosis of peripheral nerve lesions.", "content": "Galvanic tetanus and galvanic tetanus ratio in electrodiagnosis of peripheral nerve lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005313"}
{"pmid": "21005315", "title": "Intestinal intubation in bowel obstruction; technique with a new single lumen mercury weighted tube.", "content": "Intestinal intubation in bowel obstruction; technique with a new single lumen mercury weighted tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005315"}
{"pmid": "21005317", "title": "Amputations during the war and after.", "content": "Amputations during the war and after.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005317"}
{"pmid": "21005316", "title": "Deformation of the skull in head injury; a study with the stresscoat technique.", "content": "Deformation of the skull in head injury; a study with the stresscoat technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005316"}
{"pmid": "21005318", "title": "Penicillin convulsions; the convulsive effects of penicillin applied to the cerebral cortex of monkey and man.", "content": "Penicillin convulsions; the convulsive effects of penicillin applied to the cerebral cortex of monkey and man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005318"}
{"pmid": "21005320", "title": "Occupational therapy at an Army amputation and neurosurgical center.", "content": "Occupational therapy at an Army amputation and neurosurgical center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005320"}
{"pmid": "21005319", "title": "Organization of the Medical Department of the United States Army.", "content": "Organization of the Medical Department of the United States Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005319"}
{"pmid": "21005321", "title": "Some considerations regarding the training of occupational therapists.", "content": "Some considerations regarding the training of occupational therapists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005321"}
{"pmid": "21005322", "title": "A course in psychology applied to occupational therapy.", "content": "A course in psychology applied to occupational therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005322"}
{"pmid": "21005323", "title": "CHEMOTHERAPY of tuberculosis and leprosy.", "content": "CHEMOTHERAPY of tuberculosis and leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005323"}
{"pmid": "21005324", "title": "THEELIN therapy of menopause.", "content": "THEELIN therapy of menopause.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005324"}
{"pmid": "21005325", "title": "CLINICAL value of tyrothricin.", "content": "CLINICAL value of tyrothricin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005325"}
{"pmid": "21005326", "title": "SOME indications for theelin therapy.", "content": "SOME indications for theelin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005326"}
{"pmid": "21005332", "title": "Report of an attack of blackwater fever subsequent to induced malaria.", "content": "Report of an attack of blackwater fever subsequent to induced malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005332"}
{"pmid": "21005333", "title": "The douroucouli (Aotus) in laboratory cycles of yellow fever.", "content": "The douroucouli (Aotus) in laboratory cycles of yellow fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005333"}
{"pmid": "21005334", "title": "Specificity of the toxic factors associated with the epidemic and the murine strains of typhus rickettsiae.", "content": "Specificity of the toxic factors associated with the epidemic and the murine strains of typhus rickettsiae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005334"}
{"pmid": "21005335", "title": "Dengue-like fever on the Isthmus of Panama.", "content": "Dengue-like fever on the Isthmus of Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005335"}
{"pmid": "21005336", "title": "The chemotherapy of human filariasis by the administration of neostibosan.", "content": "The chemotherapy of human filariasis by the administration of neostibosan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005336"}
{"pmid": "21005337", "title": "Hyperendemicity of schistosomiasis japonica on Leyte Island, P.I.", "content": "Hyperendemicity of schistosomiasis japonica on Leyte Island, P.I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005337"}
{"pmid": "21005338", "title": "Transfusions of red cells in malaria; an experimental study in ducks.", "content": "Transfusions of red cells in malaria; an experimental study in ducks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005338"}
{"pmid": "21005339", "title": "The Rh factor in blackwater fever; a preliminary note.", "content": "The Rh factor in blackwater fever; a preliminary note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005339"}
{"pmid": "21005341", "title": "The pneumonias in Panama; a study of 500 consecutive cases.", "content": "The pneumonias in Panama; a study of 500 consecutive cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005341"}
{"pmid": "21005340", "title": "Simultaneous vaccination against bacillary dysentery and cholera with toxoid-vaccine.", "content": "Simultaneous vaccination against bacillary dysentery and cholera with toxoid-vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005340"}
{"pmid": "21005342", "title": "Rise of attack in leprosy in relation to age at exposure.", "content": "Rise of attack in leprosy in relation to age at exposure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005342"}
{"pmid": "21005343", "title": "Treatment of lambliasis with acranil.", "content": "Treatment of lambliasis with acranil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005343"}
{"pmid": "21005382", "title": "Indications for intrapleural pneumonolysis; a review of 567 thoracoscopic examinations.", "content": "Indications for intrapleural pneumonolysis; a review of 567 thoracoscopic examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005382"}
{"pmid": "21005383", "title": "Diaphragmatic paralysis and pneumoperitoneum; therapeutic observations in white patients.", "content": "Diaphragmatic paralysis and pneumoperitoneum; therapeutic observations in white patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005383"}
{"pmid": "21005384", "title": "Pneumoperitoneum and diaphragmatic paralysis; therapeutic observations in 110 Negroes.", "content": "Pneumoperitoneum and diaphragmatic paralysis; therapeutic observations in 110 Negroes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005384"}
{"pmid": "21005385", "title": "Tuberculosis in children; a comparison between postmartem material from Buffalo, New York, and Santiago, Chile.", "content": "Tuberculosis in children; a comparison between postmartem material from Buffalo, New York, and Santiago, Chile.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005385"}
{"pmid": "21005386", "title": "Degree of tuberculin sensitivity; its significance in tuberculous patients.", "content": "Degree of tuberculin sensitivity; its significance in tuberculous patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005386"}
{"pmid": "21005387", "title": "Streptomycin in experimental tuberculosis; its effect on tuberculous infections in mice produced by M. tuberculosis var. hominis.", "content": "Streptomycin in experimental tuberculosis; its effect on tuberculous infections in mice produced by M. tuberculosis var. hominis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005387"}
{"pmid": "21005388", "title": "The prognosis of chronic miliary tuberculosis in children.", "content": "The prognosis of chronic miliary tuberculosis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005388"}
{"pmid": "21005390", "title": "The metiology of silicosis.", "content": "The metiology of silicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005390"}
{"pmid": "21005389", "title": "Syphilis of the lung in Bantus.", "content": "Syphilis of the lung in Bantus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005389"}
{"pmid": "21005399", "title": "TUBERCULOSIS mortality in major cities United States, 1942-43.", "content": "TUBERCULOSIS mortality in major cities United States, 1942-43.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005399"}
{"pmid": "21005400", "title": "The glandular nodule in benign glandular enlargement of the prostate.", "content": "The glandular nodule in benign glandular enlargement of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005400"}
{"pmid": "21005401", "title": "Tubercle bacilluria.", "content": "Tubercle bacilluria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005401"}
{"pmid": "21005395", "title": "Tuberculosis in Greece; shortage of 15,000 beds.", "content": "Tuberculosis in Greece; shortage of 15,000 beds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005395"}
{"pmid": "21005402", "title": "A malignant right kidney removed at operation, together with a short length of the vena cava.", "content": "A malignant right kidney removed at operation, together with a short length of the vena cava.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005402"}
{"pmid": "21005403", "title": "Bilateral carcinoma of the adrenal cortex as a cause of severe backache with report of a case.", "content": "Bilateral carcinoma of the adrenal cortex as a cause of severe backache with report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005403"}
{"pmid": "21005404", "title": "Pyelo-cystostomy in a solitary ectopic kidney.", "content": "Pyelo-cystostomy in a solitary ectopic kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005404"}
{"pmid": "21005392", "title": "Histoplasmosis.", "content": "Histoplasmosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005392"}
{"pmid": "21005396", "title": "Comments on total thoracoscopy.", "content": "Comments on total thoracoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005396"}
{"pmid": "21005405", "title": "Renal typhoid fever: presentation of a case of the primary type.", "content": "Renal typhoid fever: presentation of a case of the primary type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005405"}
{"pmid": "21005407", "title": "Primary carcinoma of the ureter.", "content": "Primary carcinoma of the ureter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005407"}
{"pmid": "21005406", "title": "Ureterocutaneous anastomosis; a technique to eliminate permanent ureteral catheters.", "content": "Ureterocutaneous anastomosis; a technique to eliminate permanent ureteral catheters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005406"}
{"pmid": "21005408", "title": "The elasticity of the human urinary bladder.", "content": "The elasticity of the human urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005408"}
{"pmid": "21005409", "title": "Osteitis pubis following prostatectomy.", "content": "Osteitis pubis following prostatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005409"}
{"pmid": "21005398", "title": "Treatment of tuberculous laryngitis with promin (promanide).", "content": "Treatment of tuberculous laryngitis with promin (promanide).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005398"}
{"pmid": "21005410", "title": "Torsion of the appendix testis (hydatid of Morgagni) report of two cases with a study of the microscopic anatomy.", "content": "Torsion of the appendix testis (hydatid of Morgagni) report of two cases with a study of the microscopic anatomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005410"}
{"pmid": "21005411", "title": "Observations on urolithiasis among American troops in a desert area.", "content": "Observations on urolithiasis among American troops in a desert area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005411"}
{"pmid": "21005412", "title": "The use of wire in the repair of hypospadias.", "content": "The use of wire in the repair of hypospadias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005412"}
{"pmid": "21005413", "title": "Characteristics and variations in semen specimens in 100 normal young men.", "content": "Characteristics and variations in semen specimens in 100 normal young men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005413"}
{"pmid": "21005414", "title": "Trichomonas in the male.", "content": "Trichomonas in the male.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005414"}
{"pmid": "21005415", "title": "Octin as aspasmolytic in urological practice.", "content": "Octin as aspasmolytic in urological practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005415"}
{"pmid": "21005416", "title": "The improved Young urological x-ray table.", "content": "The improved Young urological x-ray table.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005416"}
{"pmid": "21005397", "title": "Tuberculosis in Holland during the war.", "content": "Tuberculosis in Holland during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005397"}
{"pmid": "21005417", "title": "Retention of urine in children due to extravesical pelvic disease; report of two cases.", "content": "Retention of urine in children due to extravesical pelvic disease; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005417"}
{"pmid": "21005419", "title": "Traumatic cord bladder in a premature infant; successful treatment by indwelling catheterization.", "content": "Traumatic cord bladder in a premature infant; successful treatment by indwelling catheterization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005419"}
{"pmid": "21005418", "title": "Varicocele due to anomalous renal vessel; an instance in a thirteen-year-old boy.", "content": "Varicocele due to anomalous renal vessel; an instance in a thirteen-year-old boy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005418"}
{"pmid": "21005420", "title": "Two cases of true hermaphroditism.", "content": "Two cases of true hermaphroditism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005420"}
{"pmid": "21005421", "title": "A new operation for mid-scrotal hypospadias.", "content": "A new operation for mid-scrotal hypospadias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005421"}
{"pmid": "21005422", "title": "Papillomatosis of bladder and entire urethra; infiltrating cancer of bladder; late pulmonary metastasis; successful pneumonectomy.", "content": "Papillomatosis of bladder and entire urethra; infiltrating cancer of bladder; late pulmonary metastasis; successful pneumonectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005422"}
{"pmid": "21005423", "title": "Infiltrating carcinoma of the bladder; relation of potential curability to depth of infiltration.", "content": "Infiltrating carcinoma of the bladder; relation of potential curability to depth of infiltration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005423"}
{"pmid": "21005424", "title": "Xanthoma and carcinoma in a diverticulum of the urinary bladder.", "content": "Xanthoma and carcinoma in a diverticulum of the urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005424"}
{"pmid": "21005425", "title": "Total cystectomy for carcinoma.", "content": "Total cystectomy for carcinoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005425"}
{"pmid": "21005426", "title": "Renal complications of Reiter's disease.", "content": "Renal complications of Reiter's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005426"}
{"pmid": "21005427", "title": "The treatment of stricture of the urethra with the high frequency cutting current.", "content": "The treatment of stricture of the urethra with the high frequency cutting current.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005427"}
{"pmid": "21005428", "title": "Penile horn.", "content": "Penile horn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005428"}
{"pmid": "21005429", "title": "Renal calculus with parathyroid adenoma.", "content": "Renal calculus with parathyroid adenoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005429"}
{"pmid": "21005430", "title": "Disappearance of renal calculi following the employment of solution G.", "content": "Disappearance of renal calculi following the employment of solution G.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005430"}
{"pmid": "21005431", "title": "Nephrolithotomy for recurrent branching calculi.", "content": "Nephrolithotomy for recurrent branching calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005431"}
{"pmid": "21005432", "title": "A case of renal hypertension.", "content": "A case of renal hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005432"}
{"pmid": "21005433", "title": "Hypertension and its relation to nephroptosis.", "content": "Hypertension and its relation to nephroptosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005433"}
{"pmid": "21005434", "title": "Primary carcinoma of ureter treated by excision and anastomosis of the cut ends.", "content": "Primary carcinoma of ureter treated by excision and anastomosis of the cut ends.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005434"}
{"pmid": "21005435", "title": "Ureteral diverticula with large stone and undeveloped kidney.", "content": "Ureteral diverticula with large stone and undeveloped kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005435"}
{"pmid": "21005436", "title": "Long-standing hydronephresis with associated urological disease; case report.", "content": "Long-standing hydronephresis with associated urological disease; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005436"}
{"pmid": "21005437", "title": "A twelve-year cure following nephrectomy for adenocarcinoma and lobectomy for solitary metastasis.", "content": "A twelve-year cure following nephrectomy for adenocarcinoma and lobectomy for solitary metastasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005437"}
{"pmid": "21005438", "title": "Tuberculoma of the spermatic cord.", "content": "Tuberculoma of the spermatic cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005438"}
{"pmid": "21005439", "title": "Prognosis in teratoma testis.", "content": "Prognosis in teratoma testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005439"}
{"pmid": "21005440", "title": "Surgery of the penis in lymphogranuloma.", "content": "Surgery of the penis in lymphogranuloma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005440"}
{"pmid": "21005441", "title": "Proteolytic enzymes and acid phosphatase in the prostatic fluid in chronic prostatitis.", "content": "Proteolytic enzymes and acid phosphatase in the prostatic fluid in chronic prostatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005441"}
{"pmid": "21005442", "title": "Orchidectomy for carcinoma of the prostate; personal experiences.", "content": "Orchidectomy for carcinoma of the prostate; personal experiences.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005442"}
{"pmid": "21005443", "title": "Treatment of prostatic carcinoma by castration and by administration of estrogenic hormone; comparison of clinical response.", "content": "Treatment of prostatic carcinoma by castration and by administration of estrogenic hormone; comparison of clinical response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005443"}
{"pmid": "21005444", "title": "Study by the newer renal function tests of an unusual case of hypertension following irradiation of one kidney and the relief of the patient by nephrectomy.", "content": "Study by the newer renal function tests of an unusual case of hypertension following irradiation of one kidney and the relief of the patient by nephrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005444"}
{"pmid": "21005445", "title": "Leiomyoma of the kidney associated with hemorrhagic cyst.", "content": "Leiomyoma of the kidney associated with hemorrhagic cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005445"}
{"pmid": "21005446", "title": "Osteonephropathy; a report of two cases.", "content": "Osteonephropathy; a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005446"}
{"pmid": "21005447", "title": "Cortical infections of polycystic kidneys.", "content": "Cortical infections of polycystic kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005447"}
{"pmid": "21005448", "title": "The problem of acidosis in urological patients.", "content": "The problem of acidosis in urological patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005448"}
{"pmid": "21005449", "title": "The use of dicoumarol and vitamin K in urological cases.", "content": "The use of dicoumarol and vitamin K in urological cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005449"}
{"pmid": "21005450", "title": "Diverticulum of the female urethra.", "content": "Diverticulum of the female urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005450"}
{"pmid": "21005451", "title": "The retardation and suppression of experimental early syphilis by small doses of penicillin comparable to those used in the treatment of gonorrhea.", "content": "The retardation and suppression of experimental early syphilis by small doses of penicillin comparable to those used in the treatment of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005451"}
{"pmid": "21005452", "title": "Studies on liver function; liver function in early syphilis before and during massive arsenotherapy.", "content": "Studies on liver function; liver function in early syphilis before and during massive arsenotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005452"}
{"pmid": "21005453", "title": "Report of a chancre developing in a patient with cardiovascular syphilis.", "content": "Report of a chancre developing in a patient with cardiovascular syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005453"}
{"pmid": "21005454", "title": "Treatment of granuloma inguinale with anthiomaline; report of case with extragenital lesion.", "content": "Treatment of granuloma inguinale with anthiomaline; report of case with extragenital lesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005454"}
{"pmid": "21005455", "title": "Lymphogranuloma venereum; diagnostic aids; the formol-gel test.", "content": "Lymphogranuloma venereum; diagnostic aids; the formol-gel test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005455"}
{"pmid": "21005456", "title": "Inguinal lymphogranuloma venereum in the male; a study of 750 consecutive cases from Panama.", "content": "Inguinal lymphogranuloma venereum in the male; a study of 750 consecutive cases from Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005456"}
{"pmid": "21005457", "title": "The in vitro action of penicillin on Hemophilus ducreyi.", "content": "The in vitro action of penicillin on Hemophilus ducreyi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005457"}
{"pmid": "21005458", "title": "Studies on chancroid; efficiency of the cultural method of diagnosis.", "content": "Studies on chancroid; efficiency of the cultural method of diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005458"}
{"pmid": "21005459", "title": "The effect of a respiratory sulfadiazine prophylactic program on the incidence of sulfonamide-resistant gonorrhea.", "content": "The effect of a respiratory sulfadiazine prophylactic program on the incidence of sulfonamide-resistant gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005459"}
{"pmid": "21005460", "title": "An accelerated schedule for the treatment of gonorrhea with penicillin on an outpatient basis.", "content": "An accelerated schedule for the treatment of gonorrhea with penicillin on an outpatient basis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005460"}
{"pmid": "21005461", "title": "The contact-education interview; its functions, principles, and techniques in venereal disease contact investigation.", "content": "The contact-education interview; its functions, principles, and techniques in venereal disease contact investigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005461"}
{"pmid": "21005462", "title": "Norfolk faces an issue; a progress report on social hygiene efforts in a war congested area.", "content": "Norfolk faces an issue; a progress report on social hygiene efforts in a war congested area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005462"}
{"pmid": "21005463", "title": "Lynchburg makes a start; a report of a venereal disease educational campaign conducted during the month of February, 1945.", "content": "Lynchburg makes a start; a report of a venereal disease educational campaign conducted during the month of February, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005463"}
{"pmid": "21005464", "title": "A city and a county cooperate; the development of a social hygiene program in the city of Danville and Pittsylvania County, Virginia.", "content": "A city and a county cooperate; the development of a social hygiene program in the city of Danville and Pittsylvania County, Virginia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005464"}
{"pmid": "21005465", "title": "Civilian committees on venereal disease control; a progress note.", "content": "Civilian committees on venereal disease control; a progress note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005465"}
{"pmid": "21005466", "title": "SOCIAL hygiene citizen groups.", "content": "SOCIAL hygiene citizen groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005466"}
{"pmid": "21005467", "title": "Treatment of granuloma inguinale with diramin; a new antimonial.", "content": "Treatment of granuloma inguinale with diramin; a new antimonial.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005467"}
{"pmid": "21005468", "title": "Comparison of gonococcus cultures read at 24 and 48 hours.", "content": "Comparison of gonococcus cultures read at 24 and 48 hours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005468"}
{"pmid": "21005469", "title": "The treatment of gonorrhea with penicillin during the incubation period or early phase of syphilis; a review.", "content": "The treatment of gonorrhea with penicillin during the incubation period or early phase of syphilis; a review.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005469"}
{"pmid": "21005470", "title": "The southward spread of the buffalo fly (Lyperosia exigua) and control methods adopted in Queensland.", "content": "The southward spread of the buffalo fly (Lyperosia exigua) and control methods adopted in Queensland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005470"}
{"pmid": "21005471", "title": "Fly movements and measures of control.", "content": "Fly movements and measures of control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005471"}
{"pmid": "21005472", "title": "The field control of contagious pleuro-pneumonia.", "content": "The field control of contagious pleuro-pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005472"}
{"pmid": "21005473", "title": "Strain 19 vaccination against contagious abortion; preliminary report on a field trial in Victoria.", "content": "Strain 19 vaccination against contagious abortion; preliminary report on a field trial in Victoria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005473"}
{"pmid": "21005474", "title": "Observations on the use of strain 19 vaccine in the field.", "content": "Observations on the use of strain 19 vaccine in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005474"}
{"pmid": "21005475", "title": "Pregnant mares' urine as a source of oestrogens.", "content": "Pregnant mares' urine as a source of oestrogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005475"}
{"pmid": "21005476", "title": "Fish-carried parasites in Canada; parasites carried by fresh-water fish.", "content": "Fish-carried parasites in Canada; parasites carried by fresh-water fish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005476"}
{"pmid": "21005478", "title": "Studies on animal dermatomycoses; clinical studies.", "content": "Studies on animal dermatomycoses; clinical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005478"}
{"pmid": "21005477", "title": "Cobalt deficiency in Nova Scotia.", "content": "Cobalt deficiency in Nova Scotia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005477"}
{"pmid": "21005479", "title": "Studies on animal dermatomycoses; cultural studies.", "content": "Studies on animal dermatomycoses; cultural studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005479"}
{"pmid": "21005480", "title": "Immunization against a lymphoid tumor of the chicken; use of centrifuged material.", "content": "Immunization against a lymphoid tumor of the chicken; use of centrifuged material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005480"}
{"pmid": "21005481", "title": "Some observations on the total ketone bodies of the blood of apparently healthy dairy cattle.", "content": "Some observations on the total ketone bodies of the blood of apparently healthy dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005481"}
{"pmid": "21005482", "title": "Measures used in the control of an infectious type of calf scours.", "content": "Measures used in the control of an infectious type of calf scours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005482"}
{"pmid": "21005483", "title": "The administration of phenothiazine and hydrocarbons to sheep.", "content": "The administration of phenothiazine and hydrocarbons to sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005483"}
{"pmid": "21005484", "title": "A simple instrument for the relief of dystocia in the bovine due to uterine torsion.", "content": "A simple instrument for the relief of dystocia in the bovine due to uterine torsion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005484"}
{"pmid": "21005485", "title": "The toxicity of a spurge (Phyllanthus abnormis) for cattle, sheep, and goats.", "content": "The toxicity of a spurge (Phyllanthus abnormis) for cattle, sheep, and goats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005485"}
{"pmid": "21005486", "title": "The opsonocytophagic test in bovine brucellosis.", "content": "The opsonocytophagic test in bovine brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005486"}
{"pmid": "21005487", "title": "Ketonemia in fetuses of a heifer and a ewe affected with severe ketosis.", "content": "Ketonemia in fetuses of a heifer and a ewe affected with severe ketosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005487"}
{"pmid": "21005488", "title": "Corynebacterium equi infection in a California foal.", "content": "Corynebacterium equi infection in a California foal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005488"}
{"pmid": "21005489", "title": "An equine hermaphrodite.", "content": "An equine hermaphrodite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005489"}
{"pmid": "21005490", "title": "Shigella equirulis infection in California.", "content": "Shigella equirulis infection in California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005490"}
{"pmid": "21005491", "title": "Treatment of strangles in a horse with penicillin and sulfamerazine.", "content": "Treatment of strangles in a horse with penicillin and sulfamerazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005491"}
{"pmid": "21005492", "title": "Malignant edema in a mare.", "content": "Malignant edema in a mare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005492"}
{"pmid": "21005493", "title": "Two unusual neoplasms in the chicken iris.", "content": "Two unusual neoplasms in the chicken iris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005493"}
{"pmid": "21005494", "title": "A review of the epizootiology of equine encephalomyelitis in the United States.", "content": "A review of the epizootiology of equine encephalomyelitis in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005494"}
{"pmid": "21005495", "title": "Advances in bacteriology and immunology in the United States.", "content": "Advances in bacteriology and immunology in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005495"}
{"pmid": "21005496", "title": "Rupture of the diaphragm.", "content": "Rupture of the diaphragm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005496"}
{"pmid": "21005498", "title": "TREATMENT of grubby cattle.", "content": "TREATMENT of grubby cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005498"}
{"pmid": "21005497", "title": "Sulfathalidine in the treatment of colibacillosis of turkey poults.", "content": "Sulfathalidine in the treatment of colibacillosis of turkey poults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005497"}
{"pmid": "21005499", "title": "Use of penicillin in acute diffuse peritonitis.", "content": "Use of penicillin in acute diffuse peritonitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005499"}
{"pmid": "21005500", "title": "VETERINARIANS and feed industry must work in close cooperation.", "content": "VETERINARIANS and feed industry must work in close cooperation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005500"}
{"pmid": "21005501", "title": "The treatment of bovine mastitis.", "content": "The treatment of bovine mastitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005501"}
{"pmid": "21005502", "title": "Fundamentals of surgical technic.", "content": "Fundamentals of surgical technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005502"}
{"pmid": "21005503", "title": "Subjective observations on brucellosis.", "content": "Subjective observations on brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005503"}
{"pmid": "21005504", "title": "Salt water and oil pollution and its relation to live stock losses.", "content": "Salt water and oil pollution and its relation to live stock losses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005504"}
{"pmid": "21005505", "title": "A case of mastitis due to Clostridium perfringens.", "content": "A case of mastitis due to Clostridium perfringens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005505"}
{"pmid": "21005506", "title": "Surgical removal of mammary tumors.", "content": "Surgical removal of mammary tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005506"}
{"pmid": "21005507", "title": "A retention of placenta in porcupine.", "content": "A retention of placenta in porcupine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005507"}
{"pmid": "21005509", "title": "RELATION of veterinary medicine to human health.", "content": "RELATION of veterinary medicine to human health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005509"}
{"pmid": "21005510", "title": "DISEASE hazards of the dairy calf.", "content": "DISEASE hazards of the dairy calf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005510"}
{"pmid": "21005511", "title": "Observations on the resistance of anthrax spores to heat.", "content": "Observations on the resistance of anthrax spores to heat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005511"}
{"pmid": "21005512", "title": "A practical method of spaying heifers.", "content": "A practical method of spaying heifers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005512"}
{"pmid": "21005513", "title": "Parasitic otorrhea.", "content": "Parasitic otorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005513"}
{"pmid": "21005514", "title": "Toxemia a result of alveolar periostitis.", "content": "Toxemia a result of alveolar periostitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005514"}
{"pmid": "21005516", "title": "The sense of smell as an aid in diagnosis.", "content": "The sense of smell as an aid in diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005516"}
{"pmid": "21005515", "title": "Canine nephritis with secondary dermatitis, hypopyon and glaucoma.", "content": "Canine nephritis with secondary dermatitis, hypopyon and glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005515"}
{"pmid": "21005517", "title": "Oophorectomy in a nymphomaniac mare.", "content": "Oophorectomy in a nymphomaniac mare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005517"}
{"pmid": "21005518", "title": "Hypersensitiveness of cattle to the ox warble.", "content": "Hypersensitiveness of cattle to the ox warble.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005518"}
{"pmid": "21005519", "title": "The examination of the stud bull for soundness.", "content": "The examination of the stud bull for soundness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005519"}
{"pmid": "21005523", "title": "A few observations on the control of disease in sheep.", "content": "A few observations on the control of disease in sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005523"}
{"pmid": "21005521", "title": "An experiment to test infectivity of cattle which are reacting to Kenya attenuated goat virus.", "content": "An experiment to test infectivity of cattle which are reacting to Kenya attenuated goat virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005521"}
{"pmid": "21005520", "title": "Sudden death of a mare from rupture of the heart.", "content": "Sudden death of a mare from rupture of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005520"}
{"pmid": "21005522", "title": "Some clinical notes, with special reference to the digestive system of the ox.", "content": "Some clinical notes, with special reference to the digestive system of the ox.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005522"}
{"pmid": "21005525", "title": "Fracture of the second phalanx (os corona) in a horse, due to enemy action.", "content": "Fracture of the second phalanx (os corona) in a horse, due to enemy action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005525"}
{"pmid": "21005524", "title": "An hereditary defect of newly-born lambs.", "content": "An hereditary defect of newly-born lambs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005524"}
{"pmid": "21005526", "title": "INTERNATIONAL biological standards.", "content": "INTERNATIONAL biological standards.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005526"}
{"pmid": "21005527", "title": "Calf diseases.", "content": "Calf diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005527"}
{"pmid": "21005528", "title": "Note on a bacterial cause of sterility in the rabbit.", "content": "Note on a bacterial cause of sterility in the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005528"}
{"pmid": "21005529", "title": "Hypocalcaemia in the mare.", "content": "Hypocalcaemia in the mare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005529"}
{"pmid": "21005530", "title": "Retention of placenta in the buffalo, with associated sequelae.", "content": "Retention of placenta in the buffalo, with associated sequelae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005530"}
{"pmid": "21005531", "title": "A student's reflections on present-day veterinary education.", "content": "A student's reflections on present-day veterinary education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005531"}
{"pmid": "21005532", "title": "Clinical applications of the human type of dental spray.", "content": "Clinical applications of the human type of dental spray.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005532"}
{"pmid": "21005533", "title": "Some observations on the oestrogenic induction of lactation in cattle.", "content": "Some observations on the oestrogenic induction of lactation in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005533"}
{"pmid": "21005534", "title": "Ovarian tumour in a bovine.", "content": "Ovarian tumour in a bovine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005534"}
{"pmid": "21005535", "title": "ARTIFICIAL insemination of livestock.", "content": "ARTIFICIAL insemination of livestock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005535"}
{"pmid": "21005536", "title": "Achievements of the Army veterinary services during the war.", "content": "Achievements of the Army veterinary services during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005536"}
{"pmid": "21005537", "title": "Studies on cestodes of the genus Triaenophorus from fish of Lesser Slave Lake, Alberta; description and life history of Triaenophorus stizostedionis n. sp.", "content": "Studies on cestodes of the genus Triaenophorus from fish of Lesser Slave Lake, Alberta; description and life history of Triaenophorus stizostedionis n. sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005537"}
{"pmid": "21005538", "title": "The mammal collections of North America.", "content": "The mammal collections of North America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005538"}
{"pmid": "21005539", "title": "Acquired homiothermism in the pregnant sloth.", "content": "Acquired homiothermism in the pregnant sloth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005539"}
{"pmid": "21005540", "title": "Double hernia of the diaphragm accompanied by hyperplasia of the biliary system and erosion of the thoracic body wall in the domestic cat.", "content": "Double hernia of the diaphragm accompanied by hyperplasia of the biliary system and erosion of the thoracic body wall in the domestic cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005540"}
{"pmid": "21005541", "title": "Heart-weight and body-weight in rodents.", "content": "Heart-weight and body-weight in rodents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005541"}
{"pmid": "21005542", "title": "Pleuritis in wild skunk.", "content": "Pleuritis in wild skunk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005542"}
{"pmid": "21005543", "title": "Cyclopia.", "content": "Cyclopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005543"}
{"pmid": "21005544", "title": "Notes on two gorilla skeletons.", "content": "Notes on two gorilla skeletons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005544"}
{"pmid": "21005545", "title": "A study of the peripheral blood of a metamorphosing anuran (Rana pipiens).", "content": "A study of the peripheral blood of a metamorphosing anuran (Rana pipiens).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005545"}
{"pmid": "21005546", "title": "Plankton of the Bermuda oceanographic expeditions; bathypelagic nemerteans of the Bermuda area and other parts of the North and South Atlantic Oceans, with evidence as to their means of dispersal.", "content": "Plankton of the Bermuda oceanographic expeditions; bathypelagic nemerteans of the Bermuda area and other parts of the North and South Atlantic Oceans, with evidence as to their means of dispersal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005546"}
{"pmid": "21005547", "title": "The microscopically demonstrable lipids of cyclic corpora lutea in the rat.", "content": "The microscopically demonstrable lipids of cyclic corpora lutea in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005547"}
{"pmid": "21005548", "title": "A determination of the diameters of ventricular myocardial fibers in man and other mammals.", "content": "A determination of the diameters of ventricular myocardial fibers in man and other mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005548"}
{"pmid": "21005549", "title": "Histochemical reactions of the endometrium in pregnancy.", "content": "Histochemical reactions of the endometrium in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005549"}
{"pmid": "21005550", "title": "A study of aero medical problems in a Liberator bomber at high altitude.", "content": "A study of aero medical problems in a Liberator bomber at high altitude.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005550"}
{"pmid": "21005551", "title": "The relationship of anoxia susceptibility to diet.", "content": "The relationship of anoxia susceptibility to diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005551"}
{"pmid": "21005553", "title": "Flying safety in the AAF.", "content": "Flying safety in the AAF.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005553"}
{"pmid": "21005552", "title": "Effect of diet on altitude tolerance.", "content": "Effect of diet on altitude tolerance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005552"}
{"pmid": "21005554", "title": "Report of death of passenger under treatment by pneumothorax.", "content": "Report of death of passenger under treatment by pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005554"}
{"pmid": "21005556", "title": "History of progressive changes in equipment used by the Medical Department.", "content": "History of progressive changes in equipment used by the Medical Department.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005556"}
{"pmid": "21005555", "title": "Effectiveness of pre-flight oxygen breathing in preventing decompression sickness.", "content": "Effectiveness of pre-flight oxygen breathing in preventing decompression sickness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005555"}
{"pmid": "21005557", "title": "An improvement in technique of the Proetz method of treating paranasal sinusitis.", "content": "An improvement in technique of the Proetz method of treating paranasal sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005557"}
{"pmid": "21005558", "title": "The antibody response of guinea pigs to epidemic typhus vaccines of various antigenicities.", "content": "The antibody response of guinea pigs to epidemic typhus vaccines of various antigenicities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005558"}
{"pmid": "21005561", "title": "The bactericidal action of bovine blood for Brucella and its possible significance.", "content": "The bactericidal action of bovine blood for Brucella and its possible significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005561"}
{"pmid": "21005560", "title": "Salmonella cultures which resemble the Sendai type.", "content": "Salmonella cultures which resemble the Sendai type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005560"}
{"pmid": "21005559", "title": "Some morphological characteristics of nodule bacteria as shown by the electron microscope. II.", "content": "Some morphological characteristics of nodule bacteria as shown by the electron microscope. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005559"}
{"pmid": "21005562", "title": "Studies on penicillin in blood; the effects of serum and serum filtrates upon the growth of Staphylococcus aureus.", "content": "Studies on penicillin in blood; the effects of serum and serum filtrates upon the growth of Staphylococcus aureus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005562"}
{"pmid": "21005563", "title": "The effect of incompletely inhibitory concentrations of penicillin on Escherichia coli.", "content": "The effect of incompletely inhibitory concentrations of penicillin on Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005563"}
{"pmid": "21005564", "title": "The isolation of hemolytic streptococci from throat swabs; the value of enrichment broth containing potassium tellurite and crystal violet.", "content": "The isolation of hemolytic streptococci from throat swabs; the value of enrichment broth containing potassium tellurite and crystal violet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005564"}
{"pmid": "21005565", "title": "A bacteriophage for Pseudomonas pyocyanea (Pseudomonas aeruginosa).", "content": "A bacteriophage for Pseudomonas pyocyanea (Pseudomonas aeruginosa).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005565"}
{"pmid": "21005566", "title": "The effect of low temperature on the spirochetes of relapsing fever.", "content": "The effect of low temperature on the spirochetes of relapsing fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005566"}
{"pmid": "21005567", "title": "The effect of low temperature on the spirochetes of relapsing fever; the structure and motility of Spirochaeta novyi.", "content": "The effect of low temperature on the spirochetes of relapsing fever; the structure and motility of Spirochaeta novyi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005567"}
{"pmid": "21005568", "title": "The nutrition of Proteus morganii: sulphur requirements.", "content": "The nutrition of Proteus morganii: sulphur requirements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005568"}
{"pmid": "21005569", "title": "alpha-Hydroxyisobutyric acid buffers (pH 2.3-5.0) not altered in pH by mold growth.", "content": "alpha-Hydroxyisobutyric acid buffers (pH 2.3-5.0) not altered in pH by mold growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005569"}
{"pmid": "21005570", "title": "A new fermentation method for mycological identification.", "content": "A new fermentation method for mycological identification.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005570"}
{"pmid": "21005571", "title": "The effect of antibiotic substances upon bacteriophage.", "content": "The effect of antibiotic substances upon bacteriophage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005571"}
{"pmid": "21005572", "title": "Some observations on the synthesis of polysaccharides by soil bacteria.", "content": "Some observations on the synthesis of polysaccharides by soil bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005572"}
{"pmid": "21005573", "title": "An improved staining method for demonstrating bacterial capsules, with particular reference to Pasteurella.", "content": "An improved staining method for demonstrating bacterial capsules, with particular reference to Pasteurella.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005573"}
{"pmid": "21005574", "title": "Microbiological aspects of penicillin; conidiospore formation in submerged cultures of Penicillium notatum.", "content": "Microbiological aspects of penicillin; conidiospore formation in submerged cultures of Penicillium notatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005574"}
{"pmid": "21005575", "title": "Bacterial collagenase.", "content": "Bacterial collagenase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005575"}
{"pmid": "21005576", "title": "Salmonella veneziana; a new type.", "content": "Salmonella veneziana; a new type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005576"}
{"pmid": "21005635", "title": "Biological assay and chemical analysis.", "content": "Biological assay and chemical analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005635"}
{"pmid": "21005636", "title": "Determination of the peroxide value of oils and fats.", "content": "Determination of the peroxide value of oils and fats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005636"}
{"pmid": "21005637", "title": "Electrometric determination of ascorbic acid.", "content": "Electrometric determination of ascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005637"}
{"pmid": "21005638", "title": "Notes on the determination of aniline in mixtures of aniline, methylaniline and dimethylaniline by the picryl chloride method.", "content": "Notes on the determination of aniline in mixtures of aniline, methylaniline and dimethylaniline by the picryl chloride method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005638"}
{"pmid": "21005639", "title": "The determination of mercury as mercuric iodate.", "content": "The determination of mercury as mercuric iodate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005639"}
{"pmid": "21005640", "title": "The determination of small quantities of silica, alumina and lime in tungsten carbide powder.", "content": "The determination of small quantities of silica, alumina and lime in tungsten carbide powder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005640"}
{"pmid": "21005641", "title": "The determination of traces of sulphur dioxide; with special reference to the determination of sulphur in ferro-alloys.", "content": "The determination of traces of sulphur dioxide; with special reference to the determination of sulphur in ferro-alloys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005641"}
{"pmid": "21005642", "title": "The rapid extraction of fat from powders.", "content": "The rapid extraction of fat from powders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005642"}
{"pmid": "21005667", "title": "Chemical characteristics and physiological roles of glutamine.", "content": "Chemical characteristics and physiological roles of glutamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005667"}
{"pmid": "21005668", "title": "Carbonyl bridge compounds and related substances.", "content": "Carbonyl bridge compounds and related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005668"}
{"pmid": "21005669", "title": "The chemistry of cinnolines.", "content": "The chemistry of cinnolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005669"}
{"pmid": "21005670", "title": "Colloid chemistry of clays.", "content": "Colloid chemistry of clays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005670"}
{"pmid": "21005676", "title": "Biotin; a stereochemical correlation of dl-biotin, dl-allobiotin and dl-epi-allobiotin.", "content": "Biotin; a stereochemical correlation of dl-biotin, dl-allobiotin and dl-epi-allobiotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005676"}
{"pmid": "21005673", "title": "Hydrogenation of compounds containing divalent sulfur.", "content": "Hydrogenation of compounds containing divalent sulfur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005673"}
{"pmid": "21005675", "title": "Biotin; resolution of dl-biotin.", "content": "Biotin; resolution of dl-biotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005675"}
{"pmid": "21005674", "title": "Biotin; synthesis of dl-biotin, dl-allobiotin and dl-epi-allobiotin.", "content": "Biotin; synthesis of dl-biotin, dl-allobiotin and dl-epi-allobiotin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005674"}
{"pmid": "21005672", "title": "X-ray investigation of glycerides; diffraction analysis of synthetic triacid triglycerides.", "content": "X-ray investigation of glycerides; diffraction analysis of synthetic triacid triglycerides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005672"}
{"pmid": "21005671", "title": "A simple synthesis of dl-desthiobiotin and related substances.", "content": "A simple synthesis of dl-desthiobiotin and related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005671"}
{"pmid": "21005677", "title": "A comparison between certain reactions of the aloins and those of glucose.", "content": "A comparison between certain reactions of the aloins and those of glucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005677"}
{"pmid": "21005678", "title": "Quinazolines; properties of 4-substituted quinazolines.", "content": "Quinazolines; properties of 4-substituted quinazolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005678"}
{"pmid": "21005679", "title": "The determination of surface tension by the sessile bubble method.", "content": "The determination of surface tension by the sessile bubble method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005679"}
{"pmid": "21005680", "title": "An x-ray diffraction investigation of sodium pectate.", "content": "An x-ray diffraction investigation of sodium pectate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005680"}
{"pmid": "21005681", "title": "Some factors influencing the ultraviolet absorption spectra of polynuclear aromatic compounds; a general survey.", "content": "Some factors influencing the ultraviolet absorption spectra of polynuclear aromatic compounds; a general survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005681"}
{"pmid": "21005682", "title": "The polymerization of olefins; the depolymerization of olefins in relation to intramolecular rearrangements.", "content": "The polymerization of olefins; the depolymerization of olefins in relation to intramolecular rearrangements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005682"}
{"pmid": "21005683", "title": "The preparation of riboflavin; the synthesis of alloxazines and isoalloxazines.", "content": "The preparation of riboflavin; the synthesis of alloxazines and isoalloxazines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005683"}
{"pmid": "21005684", "title": "The effect of sodium chloride upon the first ionization of glycine.", "content": "The effect of sodium chloride upon the first ionization of glycine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005684"}
{"pmid": "21005685", "title": "Surface area measurements of activated carbons, silica gel and other adsorbents.", "content": "Surface area measurements of activated carbons, silica gel and other adsorbents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005685"}
{"pmid": "21005686", "title": "The ultraviolet absorption spectra of cytosine and isocytosine.", "content": "The ultraviolet absorption spectra of cytosine and isocytosine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005686"}
{"pmid": "21005687", "title": "Studies in chemotherapy; antithyroid compounds; synthesis of 5- and 6-substituted 2-thiouracils from beta-oxoesters and thiourea.", "content": "Studies in chemotherapy; antithyroid compounds; synthesis of 5- and 6-substituted 2-thiouracils from beta-oxoesters and thiourea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005687"}
{"pmid": "21005688", "title": "Studies in chemotherapy; oxidation of 2-thiouracil and related compounds by iodine.", "content": "Studies in chemotherapy; oxidation of 2-thiouracil and related compounds by iodine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005688"}
{"pmid": "21005689", "title": "Synthesis of antimalarials; the synthesis of certain quinacrine analogs having N-heterocyclic groups in the alpha-position of the side chain.", "content": "Synthesis of antimalarials; the synthesis of certain quinacrine analogs having N-heterocyclic groups in the alpha-position of the side chain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005689"}
{"pmid": "21005690", "title": "A note on the effect of choline chloride on the Kahn flocculation reaction.", "content": "A note on the effect of choline chloride on the Kahn flocculation reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005690"}
{"pmid": "21005691", "title": "Synthesis of dl-methionine.", "content": "Synthesis of dl-methionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005691"}
{"pmid": "21005692", "title": "Dehydrochlorination of 1-trichloro-2-o-chlorophenyl-2-p-chlorophenylethans (o, p-DDT isomer).", "content": "Dehydrochlorination of 1-trichloro-2-o-chlorophenyl-2-p-chlorophenylethans (o, p-DDT isomer).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005692"}
{"pmid": "21005693", "title": "High molecular weight hydrocarbons.", "content": "High molecular weight hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005693"}
{"pmid": "21005694", "title": "The synthesis of some organic compounds of gold.", "content": "The synthesis of some organic compounds of gold.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005694"}
{"pmid": "21005695", "title": "The reaction of ketones with halogens and thiourea.", "content": "The reaction of ketones with halogens and thiourea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005695"}
{"pmid": "21005696", "title": "Derivatives of sulfanilamide; N4-(p-aminobenzoyl)-sulfanilamide and related compounds.", "content": "Derivatives of sulfanilamide; N4-(p-aminobenzoyl)-sulfanilamide and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005696"}
{"pmid": "21005697", "title": "The thermal degradation of pectin.", "content": "The thermal degradation of pectin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005697"}
{"pmid": "21005698", "title": "Derivatives of 2-keto-3,4-imidazolidothiophene.", "content": "Derivatives of 2-keto-3,4-imidazolidothiophene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005698"}
{"pmid": "21005699", "title": "Studies in the anthracene series; methyl ketones and carbinol-amines derived from 1,2,3,4,-tetrahydroanthracene.", "content": "Studies in the anthracene series; methyl ketones and carbinol-amines derived from 1,2,3,4,-tetrahydroanthracene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005699"}
{"pmid": "21005700", "title": "Isomerization of alkyl phosphites; the synthesis of some alkaryl phosphonic acids and esters.", "content": "Isomerization of alkyl phosphites; the synthesis of some alkaryl phosphonic acids and esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005700"}
{"pmid": "21005702", "title": "Note on a new color reaction of beta-chlorovinyldichloroarsine.", "content": "Note on a new color reaction of beta-chlorovinyldichloroarsine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005702"}
{"pmid": "21005701", "title": "Chemical nature of the insecticidal principle in mamey seed.", "content": "Chemical nature of the insecticidal principle in mamey seed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005701"}
{"pmid": "21005703", "title": "Some crystalline forms of amylose.", "content": "Some crystalline forms of amylose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005703"}
{"pmid": "21005704", "title": "alpha-methoxycrotonic acid.", "content": "alpha-methoxycrotonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005704"}
{"pmid": "21005705", "title": "1-acetyl-5,5-dimethylhydantoin.", "content": "1-acetyl-5,5-dimethylhydantoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005705"}
{"pmid": "21005706", "title": "Determination of the nature of the volatile base from the rhizome of the pitcher plant Sarracenia purpura.", "content": "Determination of the nature of the volatile base from the rhizome of the pitcher plant Sarracenia purpura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005706"}
{"pmid": "21005707", "title": "The isolation of a new leukopoietic factor from liver.", "content": "The isolation of a new leukopoietic factor from liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005707"}
{"pmid": "21005708", "title": "A new method of producing fused ring structures related to the steroids; a synthesis of equilenin.", "content": "A new method of producing fused ring structures related to the steroids; a synthesis of equilenin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005708"}
{"pmid": "21005709", "title": "The formation of maltol by the degradation of streptomycin.", "content": "The formation of maltol by the degradation of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005709"}
{"pmid": "21005710", "title": "An electrophoretic survey of various animal plasmas.", "content": "An electrophoretic survey of various animal plasmas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005710"}
{"pmid": "21005711", "title": "Species difference in serum protein patterns.", "content": "Species difference in serum protein patterns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005711"}
{"pmid": "21005713", "title": "The relationship between vitamin M and the Lactobacillus casei factor.", "content": "The relationship between vitamin M and the Lactobacillus casei factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005713"}
{"pmid": "21005712", "title": "Experimentally induced changes in the prothrombin level of the blood; quantitative studies in dogs given dicumarol; the effect of methylxanthines on prothrombin per se and when administered with dicumarol.", "content": "Experimentally induced changes in the prothrombin level of the blood; quantitative studies in dogs given dicumarol; the effect of methylxanthines on prothrombin per se and when administered with dicumarol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005712"}
{"pmid": "21005714", "title": "The effects of various inhibitors of carbohydrate metabolism in vivo.", "content": "The effects of various inhibitors of carbohydrate metabolism in vivo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005714"}
{"pmid": "21005715", "title": "The fractionation of lecithins and cephalins.", "content": "The fractionation of lecithins and cephalins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005715"}
{"pmid": "21005716", "title": "A simplified preparation of cardiolipin, with note on purification of lecithin for serologic use.", "content": "A simplified preparation of cardiolipin, with note on purification of lecithin for serologic use.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005716"}
{"pmid": "21005717", "title": "A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues.", "content": "A method for the determination of desoxyribonucleic acid, ribonucleic acid, and phosphoproteins in animal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005717"}
{"pmid": "21005718", "title": "Conjugated forms of myelokentric and lymphokentric acids.", "content": "Conjugated forms of myelokentric and lymphokentric acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005718"}
{"pmid": "21005719", "title": "A convenient microtitration method for the estimation of amino acids.", "content": "A convenient microtitration method for the estimation of amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005719"}
{"pmid": "21005720", "title": "The effect of parathyroid extract upon the distribution, retention, and excretion of labeled strontium.", "content": "The effect of parathyroid extract upon the distribution, retention, and excretion of labeled strontium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005720"}
{"pmid": "21005721", "title": "The effect of dose and nutritive state on kidney arginase after steroid stimulation.", "content": "The effect of dose and nutritive state on kidney arginase after steroid stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005721"}
{"pmid": "21005723", "title": "The effect of environmental temperature and potassium iodide supplementation on the excretion of iodine by normal human subjects.", "content": "The effect of environmental temperature and potassium iodide supplementation on the excretion of iodine by normal human subjects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005723"}
{"pmid": "21005724", "title": "The effect of pantothenic acid dosage and environmental temperature and humidity upon the dermal and renal excretion of pantothenic acid.", "content": "The effect of pantothenic acid dosage and environmental temperature and humidity upon the dermal and renal excretion of pantothenic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005724"}
{"pmid": "21005722", "title": "The microdetermination of iodine in biological materials with special reference to the combustion of samples in the Parr oxygen bomb.", "content": "The microdetermination of iodine in biological materials with special reference to the combustion of samples in the Parr oxygen bomb.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005722"}
{"pmid": "21005725", "title": "Oxygen poisoning; the effect of high oxygen pressure upon enzymes; succinicdehydrogenase and cytochrome oxidase.", "content": "Oxygen poisoning; the effect of high oxygen pressure upon enzymes; succinicdehydrogenase and cytochrome oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005725"}
{"pmid": "21005726", "title": "Oxygen poisoning; the effect of high oxygen pressure upon enzymes; pepsin, catalase, cholinesterase, and carbonic anhydrase.", "content": "Oxygen poisoning; the effect of high oxygen pressure upon enzymes; pepsin, catalase, cholinesterase, and carbonic anhydrase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005726"}
{"pmid": "21005727", "title": "Oxygen poisoning; the effect of high oxygen pressure upon enzymes; uricase, xanthine oxidase, and alpha-amino acid oxidase.", "content": "Oxygen poisoning; the effect of high oxygen pressure upon enzymes; uricase, xanthine oxidase, and alpha-amino acid oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005727"}
{"pmid": "21005728", "title": "Oxygen poisoning; the effect of high oxygen pressure on enzymes; the system synthesizing acetylcholine.", "content": "Oxygen poisoning; the effect of high oxygen pressure on enzymes; the system synthesizing acetylcholine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005728"}
{"pmid": "21005729", "title": "Anaerobic glycolysis in nervous tissue.", "content": "Anaerobic glycolysis in nervous tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005729"}
{"pmid": "21005730", "title": "The role of maltase in the enzymolysis of raw starch.", "content": "The role of maltase in the enzymolysis of raw starch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005730"}
{"pmid": "21005731", "title": "Isolation of steroids from the urine of patients with adrenal cortical tumors and adrenal cortical hyperplasia; a new 17-ketosteroid, androstane-3 (alpha) 11-diol-17-one.", "content": "Isolation of steroids from the urine of patients with adrenal cortical tumors and adrenal cortical hyperplasia; a new 17-ketosteroid, androstane-3 (alpha) 11-diol-17-one.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005731"}
{"pmid": "21005732", "title": "Esterification of proteins with alcohols of low molecular weight.", "content": "Esterification of proteins with alcohols of low molecular weight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005732"}
{"pmid": "21005733", "title": "The isolation of pregnandiol-3 alpha, 17-one-20 from human urine.", "content": "The isolation of pregnandiol-3 alpha, 17-one-20 from human urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005733"}
{"pmid": "21005734", "title": "The metabolism in vivo of dl-phenylalanine in thiamine deficiency.", "content": "The metabolism in vivo of dl-phenylalanine in thiamine deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005734"}
{"pmid": "21005735", "title": "2,3-Diphenacyl and para-substituted diphenacyl ascorbic acid.", "content": "2,3-Diphenacyl and para-substituted diphenacyl ascorbic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005735"}
{"pmid": "21005736", "title": "Phosphorus compounds in animal tissues; extraction and estimation of desoxypentose nucleic acid and of pentose nucleic acid.", "content": "Phosphorus compounds in animal tissues; extraction and estimation of desoxypentose nucleic acid and of pentose nucleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005736"}
{"pmid": "21005737", "title": "The vitamin A activity of neo-beta-carotene U and its steric rearrangement in the digestive tract of rats.", "content": "The vitamin A activity of neo-beta-carotene U and its steric rearrangement in the digestive tract of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005737"}
{"pmid": "21005738", "title": "Function of the vitamin B6 group; pyridoxal phosphate (codecarboxylase) in transamination.", "content": "Function of the vitamin B6 group; pyridoxal phosphate (codecarboxylase) in transamination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005738"}
{"pmid": "21005739", "title": "Identification of small amounts of organic compounds by distribution studies; the use of buffers in counter-current distribution.", "content": "Identification of small amounts of organic compounds by distribution studies; the use of buffers in counter-current distribution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005739"}
{"pmid": "21005744", "title": "The antioxygenic synergism of tocopherol and rice bran extract in the preservation of carotene.", "content": "The antioxygenic synergism of tocopherol and rice bran extract in the preservation of carotene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005744"}
{"pmid": "21005740", "title": "An amine ed formed by bacteria during sulfonamide bacteriostasis.", "content": "An amine ed formed by bacteria during sulfonamide bacteriostasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005740"}
{"pmid": "21005741", "title": "The excretion of ascorbic acid and dehydroascorbic acid in sweat and urine under different environmental conditions.", "content": "The excretion of ascorbic acid and dehydroascorbic acid in sweat and urine under different environmental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005741"}
{"pmid": "21005742", "title": "The occurrence of inositol and of p-amino benzoic acid in sweat.", "content": "The occurrence of inositol and of p-amino benzoic acid in sweat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005742"}
{"pmid": "21005745", "title": "Cyanide loss from media in studies of tissue metabolism in vitro.", "content": "Cyanide loss from media in studies of tissue metabolism in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005745"}
{"pmid": "21005743", "title": "Further studies of the purification and properties of the amylase of Aspergillus oryzae.", "content": "Further studies of the purification and properties of the amylase of Aspergillus oryzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005743"}
{"pmid": "21005746", "title": "The isolation of preparations of thromboplastic protein from human organs.", "content": "The isolation of preparations of thromboplastic protein from human organs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005746"}
{"pmid": "21005748", "title": "The micro biological activity of dl-oxybiotin and related compounds.", "content": "The micro biological activity of dl-oxybiotin and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005748"}
{"pmid": "21005747", "title": "Studies on the liberation of compounds in the folic acid group.", "content": "Studies on the liberation of compounds in the folic acid group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005747"}
{"pmid": "21005749", "title": "Incorporation of acetate carbon into rat liver glycogen by pathways other than carbon dioxide fixation.", "content": "Incorporation of acetate carbon into rat liver glycogen by pathways other than carbon dioxide fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005749"}
{"pmid": "21005750", "title": "Fatty acid oxidation and the Krebs trocarboxylic acid cycle.", "content": "Fatty acid oxidation and the Krebs trocarboxylic acid cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005750"}
{"pmid": "21005751", "title": "The detection of activated carboxyl groups with hydroxylamine as interceptor.", "content": "The detection of activated carboxyl groups with hydroxylamine as interceptor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005751"}
{"pmid": "21005752", "title": "The fate of N1-methylnicotinamide in man.", "content": "The fate of N1-methylnicotinamide in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005752"}
{"pmid": "21005754", "title": "Some problems in children's dentistry.", "content": "Some problems in children's dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005754"}
{"pmid": "21005753", "title": "Hydrolysis of phenylacetylcholine by esterases.", "content": "Hydrolysis of phenylacetylcholine by esterases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005753"}
{"pmid": "21005755", "title": "The gold foil filling.", "content": "The gold foil filling.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005755"}
{"pmid": "21005756", "title": "The use of vibration in the insertion of amalgam fillings.", "content": "The use of vibration in the insertion of amalgam fillings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005756"}
{"pmid": "21005757", "title": "The degeneracy of civilization.", "content": "The degeneracy of civilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005757"}
{"pmid": "21005759", "title": "The diagnostic value of radiographic examination for proximal caries in the deciduous posterior teeth.", "content": "The diagnostic value of radiographic examination for proximal caries in the deciduous posterior teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005759"}
{"pmid": "21005758", "title": "The significance of the living organic tissue of the teeth in dental caries.", "content": "The significance of the living organic tissue of the teeth in dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005758"}
{"pmid": "21005760", "title": "Thumb and finger sucking.", "content": "Thumb and finger sucking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005760"}
{"pmid": "21005761", "title": "The disintegration of the calcium salts in the teeth by the action of sodium hydroxide on the organic matrix.", "content": "The disintegration of the calcium salts in the teeth by the action of sodium hydroxide on the organic matrix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005761"}
{"pmid": "21005762", "title": "Practical application after one more year's research and progress in acrylics.", "content": "Practical application after one more year's research and progress in acrylics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005762"}
{"pmid": "21005763", "title": "Dental caries; a study of regional variations in New Zealand.", "content": "Dental caries; a study of regional variations in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005763"}
{"pmid": "21005764", "title": "An adequate supply of milk of good quality for human consumption.", "content": "An adequate supply of milk of good quality for human consumption.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005764"}
{"pmid": "21005765", "title": "A nine year history of a nontorque clasp.", "content": "A nine year history of a nontorque clasp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005765"}
{"pmid": "21005766", "title": "Dentistry and the School Health Act.", "content": "Dentistry and the School Health Act.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005766"}
{"pmid": "21005769", "title": "Chemoresistance in gonorrhea.", "content": "Chemoresistance in gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005769"}
{"pmid": "21005770", "title": "Treatment of impetigo herpetiformis in pregnant women with hormones.", "content": "Treatment of impetigo herpetiformis in pregnant women with hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005770"}
{"pmid": "21005771", "title": "On a fungus capable of producing acid-fast rods with special regard to its occurrence in lymphogranulomatosis benigna (Schaumann's disease).", "content": "On a fungus capable of producing acid-fast rods with special regard to its occurrence in lymphogranulomatosis benigna (Schaumann's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005771"}
{"pmid": "21005772", "title": "On the combating of the venereal diseases in the mercantile marine.", "content": "On the combating of the venereal diseases in the mercantile marine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005772"}
{"pmid": "21005773", "title": "Transfusion-transmission of lues to mother and child.", "content": "Transfusion-transmission of lues to mother and child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005773"}
{"pmid": "21005774", "title": "Acanthosis nigricans associated with carcinoma of the gallbladder and plantar hyperkeratosis; report of a case.", "content": "Acanthosis nigricans associated with carcinoma of the gallbladder and plantar hyperkeratosis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005774"}
{"pmid": "21005776", "title": "Acne conglobata.", "content": "Acne conglobata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005776"}
{"pmid": "21005777", "title": "A case of progressive muscular dystrophy combined with syndroma Cushing.", "content": "A case of progressive muscular dystrophy combined with syndroma Cushing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005777"}
{"pmid": "21005775", "title": "Boeck's sarcoid.", "content": "Boeck's sarcoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005775"}
{"pmid": "21005779", "title": "Essential, teleangiectasia diffusa.", "content": "Essential, teleangiectasia diffusa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005779"}
{"pmid": "21005778", "title": "Epidermolysis bullosa hereditaria dystrophica, with hypochromic anemia.", "content": "Epidermolysis bullosa hereditaria dystrophica, with hypochromic anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005778"}
{"pmid": "21005780", "title": "Erythematodes treated with sulphonamide.", "content": "Erythematodes treated with sulphonamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005780"}
{"pmid": "21005781", "title": "Syphilis; source of infection.", "content": "Syphilis; source of infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005781"}
{"pmid": "21005782", "title": "Eczema vaccinatum.", "content": "Eczema vaccinatum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005782"}
{"pmid": "21005783", "title": "A case of thrombosis in vena iliaca communis shown in venography.", "content": "A case of thrombosis in vena iliaca communis shown in venography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005783"}
{"pmid": "21005784", "title": "A case of idiopathic, subungual hemorrhage with onycholysis.", "content": "A case of idiopathic, subungual hemorrhage with onycholysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005784"}
{"pmid": "21005785", "title": "The new remedy against scabies, dixanthogen ointment; Dixan Nyco.", "content": "The new remedy against scabies, dixanthogen ointment; Dixan Nyco.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005785"}
{"pmid": "21005786", "title": "A case of dermato-sarcoma.", "content": "A case of dermato-sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005786"}
{"pmid": "21005787", "title": "Morbus Pringle, tuberous cerebral sclerosis.", "content": "Morbus Pringle, tuberous cerebral sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005787"}
{"pmid": "21005788", "title": "Hypochromic anemia with epithelial changes and acne rosacea.", "content": "Hypochromic anemia with epithelial changes and acne rosacea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005788"}
{"pmid": "21005789", "title": "Lues III with peculiar trabecular cicatrix formation in the palate.", "content": "Lues III with peculiar trabecular cicatrix formation in the palate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005789"}
{"pmid": "21005885", "title": "A new cutaneous syndrome occurring in New Guinea and adjacent islands; preliminary report.", "content": "A new cutaneous syndrome occurring in New Guinea and adjacent islands; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005885"}
{"pmid": "21005886", "title": "Clinical investigation of a new cutaneous entity. [New Guinea skin disease].", "content": "Clinical investigation of a new cutaneous entity. [New Guinea skin disease].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005886"}
{"pmid": "21005887", "title": "Beta dimethylaminoethyl benzhydryl ether hydrochloride (benadryl) in treatment of urticaria.", "content": "Beta dimethylaminoethyl benzhydryl ether hydrochloride (benadryl) in treatment of urticaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005887"}
{"pmid": "21005888", "title": "Use of benadryl for urticaria and related dermatoses; a preliminary report.", "content": "Use of benadryl for urticaria and related dermatoses; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005888"}
{"pmid": "21005889", "title": "Penicillin ointment.", "content": "Penicillin ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005889"}
{"pmid": "21005890", "title": "Diseases of the skin among the natives of northeast New Guinea.", "content": "Diseases of the skin among the natives of northeast New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005890"}
{"pmid": "21005891", "title": "Sensitivity of the tuberculin patch test (Vollmer-Lederle).", "content": "Sensitivity of the tuberculin patch test (Vollmer-Lederle).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005891"}
{"pmid": "21005892", "title": "Effect of feeding a lipotropic substance to patients with xanthelasma.", "content": "Effect of feeding a lipotropic substance to patients with xanthelasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005892"}
{"pmid": "21005893", "title": "Relation of ultraviolet-induced mutations to speciation in dermatophytes.", "content": "Relation of ultraviolet-induced mutations to speciation in dermatophytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005893"}
{"pmid": "21005894", "title": "Contact dermatitis of eyelids caused by an antioxidant in rubber fillers of eyelash curlers; report of 7 cases.", "content": "Contact dermatitis of eyelids caused by an antioxidant in rubber fillers of eyelash curlers; report of 7 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005894"}
{"pmid": "21005895", "title": "Scrotal tongue and its inheritance.", "content": "Scrotal tongue and its inheritance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005895"}
{"pmid": "21005896", "title": "An improved method for preparing permanent slides of fungus cultures.", "content": "An improved method for preparing permanent slides of fungus cultures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005896"}
{"pmid": "21005897", "title": "Course in tropical dermatology.", "content": "Course in tropical dermatology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005897"}
{"pmid": "21005898", "title": "A case for diagnosis; fixed bismuth dermatitis?", "content": "A case for diagnosis; fixed bismuth dermatitis?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005898"}
{"pmid": "21005899", "title": "Nodular interstitial glossitis due to syphilis.", "content": "Nodular interstitial glossitis due to syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005899"}
{"pmid": "21005900", "title": "Disseminated granuloma annulare with atrophy.", "content": "Disseminated granuloma annulare with atrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005900"}
{"pmid": "21005901", "title": "Contact dermatitis due to protek.", "content": "Contact dermatitis due to protek.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005901"}
{"pmid": "21005902", "title": "Pseudoatrophoderma coli et corporis.", "content": "Pseudoatrophoderma coli et corporis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005902"}
{"pmid": "21005904", "title": "Epidermolysis bullosa hereditaria.", "content": "Epidermolysis bullosa hereditaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005904"}
{"pmid": "21005903", "title": "Multiple benign superficial epithelioma.", "content": "Multiple benign superficial epithelioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005903"}
{"pmid": "21005905", "title": "Multiple neurofibromatosis of a peculiar papular form.", "content": "Multiple neurofibromatosis of a peculiar papular form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005905"}
{"pmid": "21005906", "title": "Macular atrophy of the buttocks.", "content": "Macular atrophy of the buttocks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005906"}
{"pmid": "21005907", "title": "Tinea circinata.", "content": "Tinea circinata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005907"}
{"pmid": "21005908", "title": "Synovial cyst and psoriasis.", "content": "Synovial cyst and psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005908"}
{"pmid": "21005909", "title": "Lymphosarcoma of the nose.", "content": "Lymphosarcoma of the nose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005909"}
{"pmid": "21005910", "title": "Lupus vulgaris.", "content": "Lupus vulgaris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005910"}
{"pmid": "21005911", "title": "Bowen's disease.", "content": "Bowen's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005911"}
{"pmid": "21005912", "title": "Lepra maculoanesthetica.", "content": "Lepra maculoanesthetica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005912"}
{"pmid": "21005913", "title": "Necrobiosis lipoidica diabeticorum.", "content": "Necrobiosis lipoidica diabeticorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005913"}
{"pmid": "21005914", "title": "Dermatitis herpetiformis treated with acetarsone.", "content": "Dermatitis herpetiformis treated with acetarsone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005914"}
{"pmid": "21005915", "title": "Fungous infection of the back of the neck.", "content": "Fungous infection of the back of the neck.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005915"}
{"pmid": "21005916", "title": "Tuberculosis cutis (?) and psoriasis.", "content": "Tuberculosis cutis (?) and psoriasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005916"}
{"pmid": "21005917", "title": "Xanthoma, or lipid disturbance.", "content": "Xanthoma, or lipid disturbance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005917"}
{"pmid": "21005918", "title": "A case for diagnosis (pustular bacterid?).", "content": "A case for diagnosis (pustular bacterid?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005918"}
{"pmid": "21005919", "title": "A case for diagnosis (achromic nevus; atypical hydroa puerorum?).", "content": "A case for diagnosis (achromic nevus; atypical hydroa puerorum?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005919"}
{"pmid": "21005920", "title": "Pemphigus vulgaris, improved by acetarsone.", "content": "Pemphigus vulgaris, improved by acetarsone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005920"}
{"pmid": "21005936", "title": "Necrobiosis lipoidica.", "content": "Necrobiosis lipoidica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005936"}
{"pmid": "21005955", "title": "Lichen sclerosus atrophicus (white spot disease).", "content": "Lichen sclerosus atrophicus (white spot disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005955"}
{"pmid": "21005963", "title": "Frozen sections from Bouin-fixed material in histopathology.", "content": "Frozen sections from Bouin-fixed material in histopathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005963"}
{"pmid": "21005962", "title": "Progress in the standardization of stains; the work of the Stain Commission.", "content": "Progress in the standardization of stains; the work of the Stain Commission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005962"}
{"pmid": "21005964", "title": "Substitutes for ethyl alcohol.", "content": "Substitutes for ethyl alcohol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005964"}
{"pmid": "21005965", "title": "A tissue basket for paraffin infiltration.", "content": "A tissue basket for paraffin infiltration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005965"}
{"pmid": "21005966", "title": "Prefixing with paradichlorobenzene to facilitate chromosome study.", "content": "Prefixing with paradichlorobenzene to facilitate chromosome study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005966"}
{"pmid": "21005967", "title": "A combination bleaching-clearing agent and its use in the processing of Spalteholz preparations.", "content": "A combination bleaching-clearing agent and its use in the processing of Spalteholz preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005967"}
{"pmid": "21005968", "title": "The use of certain phthalate compounds in embryology.", "content": "The use of certain phthalate compounds in embryology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005968"}
{"pmid": "21005969", "title": "The use of dimethoxytetraethyleneglycol and triethyl phosphate in histological technic.", "content": "The use of dimethoxytetraethyleneglycol and triethyl phosphate in histological technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005969"}
{"pmid": "21005970", "title": "The Venetian turpentine mounting medium.", "content": "The Venetian turpentine mounting medium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005970"}
{"pmid": "21005971", "title": "A device to aid paraffin embedding.", "content": "A device to aid paraffin embedding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005971"}
{"pmid": "21005972", "title": "Method for affixing celloidin sections.", "content": "Method for affixing celloidin sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005972"}
{"pmid": "21005973", "title": "The clinical significance of cholesterol.", "content": "The clinical significance of cholesterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005973"}
{"pmid": "21005974", "title": "The effect of bile salts on the experimental production of ulcers in the dog.", "content": "The effect of bile salts on the experimental production of ulcers in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005974"}
{"pmid": "21005975", "title": "Hyperinsulinism as a factor in peptic ulcer.", "content": "Hyperinsulinism as a factor in peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005975"}
{"pmid": "21005987", "title": "Fungus disease of the spleen, report of a case.", "content": "Fungus disease of the spleen, report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005987"}
{"pmid": "21005988", "title": "Dietary considerations in malignant neoplastic diseases; a preliminary report.", "content": "Dietary considerations in malignant neoplastic diseases; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005988"}
{"pmid": "21005989", "title": "A new aspect in treatment of amebiasis.", "content": "A new aspect in treatment of amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005989"}
{"pmid": "21005990", "title": "Profenil; a new antispasmodic; a preliminary report.", "content": "Profenil; a new antispasmodic; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005990"}
{"pmid": "21005992", "title": "Hereditary ataxia.", "content": "Hereditary ataxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005992"}
{"pmid": "21005991", "title": "Genotype and temperature in relation to symptoms caused in Nicotiana by the mosaic virus; studies on the necrosis and the mottling reactions in certain species of Nicotiana and in tobacco hybrids infected with tobaccomosaic virus.", "content": "Genotype and temperature in relation to symptoms caused in Nicotiana by the mosaic virus; studies on the necrosis and the mottling reactions in certain species of Nicotiana and in tobacco hybrids infected with tobaccomosaic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005991"}
{"pmid": "21005993", "title": "A genetic analysis of the American quarter horse.", "content": "A genetic analysis of the American quarter horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005993"}
{"pmid": "21005996", "title": "The physician in the ancient Utopias.", "content": "The physician in the ancient Utopias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005996"}
{"pmid": "21005997", "title": "Medicine in the Utopias of the Renaissance and the 17th Century.", "content": "Medicine in the Utopias of the Renaissance and the 17th Century.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005997"}
{"pmid": "21005998", "title": "Medicine in Utopia, from the 18th Century to the present.", "content": "Medicine in Utopia, from the 18th Century to the present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005998"}
{"pmid": "21005999", "title": "Contributed articles to the Homeopathic Medical Society of the State of Pennsylvania.", "content": "Contributed articles to the Homeopathic Medical Society of the State of Pennsylvania.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21005999"}
{"pmid": "21006000", "title": "The toxicity of cosmetics.", "content": "The toxicity of cosmetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006000"}
{"pmid": "21006001", "title": "The roentgen treatment of inflammations.", "content": "The roentgen treatment of inflammations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006001"}
{"pmid": "21006012", "title": "Normal esterase and pancreatic lipase in the blood; a study with new chemical and clinical methods (a second secretin test).", "content": "Normal esterase and pancreatic lipase in the blood; a study with new chemical and clinical methods (a second secretin test).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006012"}
{"pmid": "21006013", "title": "The histopathology of the liver in infectious mononucleosis complicated by jaundice, investigated by aspiration biopsy.", "content": "The histopathology of the liver in infectious mononucleosis complicated by jaundice, investigated by aspiration biopsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006013"}
{"pmid": "21006014", "title": "Investigations on the use of the phycomyces method in the estimation of vitamin B1 in blood.", "content": "Investigations on the use of the phycomyces method in the estimation of vitamin B1 in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006014"}
{"pmid": "21006015", "title": "Oscillometric studies; on the change of sensitivity of the oscillometer at the different pressures, and on the influence of the state of contraction of the arterial wall on the oscillometric curve.", "content": "Oscillometric studies; on the change of sensitivity of the oscillometer at the different pressures, and on the influence of the state of contraction of the arterial wall on the oscillometric curve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006015"}
{"pmid": "21006016", "title": "Studies on hyperventilation; influence of the carbon dioxide tension in the arterial blood on the state of contraction of the large arteries in man.", "content": "Studies on hyperventilation; influence of the carbon dioxide tension in the arterial blood on the state of contraction of the large arteries in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006016"}
{"pmid": "21006018", "title": "Raynaud's phenomenon in riveters.", "content": "Raynaud's phenomenon in riveters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006018"}
{"pmid": "21006019", "title": "Studies on the effort syndrome; the conditions of the large arteries during muscular work illustrated by oscillometric measurements.", "content": "Studies on the effort syndrome; the conditions of the large arteries during muscular work illustrated by oscillometric measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006019"}
{"pmid": "21006020", "title": "Rothmund-Werner's disease; a case with internal frontal hyperostosis.", "content": "Rothmund-Werner's disease; a case with internal frontal hyperostosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006020"}
{"pmid": "21006021", "title": "Thiouracil therapy in thyrotoxicosis; preliminary report.", "content": "Thiouracil therapy in thyrotoxicosis; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006021"}
{"pmid": "21006022", "title": "Seasonal variations in morbidity in cases of gastric ulcer and duodenal ulcer.", "content": "Seasonal variations in morbidity in cases of gastric ulcer and duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006022"}
{"pmid": "21006025", "title": "Intermittent claudication and vascular spasm; can intermittent claudication be due to vascular spasm without accompanying structural disease of the arteries?", "content": "Intermittent claudication and vascular spasm; can intermittent claudication be due to vascular spasm without accompanying structural disease of the arteries?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006025"}
{"pmid": "21006026", "title": "Methylthiouracil therapy in thyrotoxicosis; preliminary report.", "content": "Methylthiouracil therapy in thyrotoxicosis; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006026"}
{"pmid": "21006027", "title": "Increasing incidence of hyperthyreoidism in Denmark.", "content": "Increasing incidence of hyperthyreoidism in Denmark.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006027"}
{"pmid": "21006028", "title": "Angiospastic encephalopathy.", "content": "Angiospastic encephalopathy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006028"}
{"pmid": "21006029", "title": "Steatorrhoea arthro, pericarditica (mesenteric chyladenectasis); review and report of a case.", "content": "Steatorrhoea arthro, pericarditica (mesenteric chyladenectasis); review and report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006029"}
{"pmid": "21006030", "title": "The antistreptolysin titer in glomerular nephritis.", "content": "The antistreptolysin titer in glomerular nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006030"}
{"pmid": "21006031", "title": "Welding regarded from the medical point of view.", "content": "Welding regarded from the medical point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006031"}
{"pmid": "21006032", "title": "Exudative pleuritis as a symptom in cases of malign lymphogranulomatosis.", "content": "Exudative pleuritis as a symptom in cases of malign lymphogranulomatosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006032"}
{"pmid": "21006033", "title": "On pre-excitation (WPW syndrome).", "content": "On pre-excitation (WPW syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006033"}
{"pmid": "21006034", "title": "The effect on muscular temperature produced by cooling normal and ultraviolet radiated skin.", "content": "The effect on muscular temperature produced by cooling normal and ultraviolet radiated skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006034"}
{"pmid": "21006035", "title": "Fiedler's myocarditis; infectious myocarditis.", "content": "Fiedler's myocarditis; infectious myocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006035"}
{"pmid": "21006036", "title": "Exophthalmic goiter developing after treatment with thyroid preparations.", "content": "Exophthalmic goiter developing after treatment with thyroid preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006036"}
{"pmid": "21006037", "title": "On cyanosis.", "content": "On cyanosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006037"}
{"pmid": "21006038", "title": "Determination of vitamin B1 in the blood from healthy and diseased persons.", "content": "Determination of vitamin B1 in the blood from healthy and diseased persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006038"}
{"pmid": "21006039", "title": "Acute and subacute hemolytic anemia of unknown origin (type Lederer); report and discussion of 3 cases.", "content": "Acute and subacute hemolytic anemia of unknown origin (type Lederer); report and discussion of 3 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006039"}
{"pmid": "21006040", "title": "Nine cases of Graves' disease developed in connection with thyroid gland therapy.", "content": "Nine cases of Graves' disease developed in connection with thyroid gland therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006040"}
{"pmid": "21006041", "title": "Diaphragm contractions synchronizing with the heart movements.", "content": "Diaphragm contractions synchronizing with the heart movements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006041"}
{"pmid": "21006042", "title": "Convalescence from surgical procedures; studies of the circulation lying and standing, of tremor, and of a program of bed exercise and early rising.", "content": "Convalescence from surgical procedures; studies of the circulation lying and standing, of tremor, and of a program of bed exercise and early rising.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006042"}
{"pmid": "21006043", "title": "Convalescence from surgical procedures; studies of various physiological responses to a mild exercise test.", "content": "Convalescence from surgical procedures; studies of various physiological responses to a mild exercise test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006043"}
{"pmid": "21006044", "title": "Coarctation and acute dissection of the aorta associated with pregnancy.", "content": "Coarctation and acute dissection of the aorta associated with pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006044"}
{"pmid": "21006045", "title": "Combined acute vascular lesions of brain and heart; a clinical-pathologic study of 15 cases.", "content": "Combined acute vascular lesions of brain and heart; a clinical-pathologic study of 15 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006045"}
{"pmid": "21006046", "title": "The relationship between cells and plasma in cultures of the buffy coat from human blood.", "content": "The relationship between cells and plasma in cultures of the buffy coat from human blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006046"}
{"pmid": "21006047", "title": "Choriocarcinoma of the testicle.", "content": "Choriocarcinoma of the testicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006047"}
{"pmid": "21006050", "title": "Incidence of respiratory infections following attack by primary atypical pneumonia is unchanged.", "content": "Incidence of respiratory infections following attack by primary atypical pneumonia is unchanged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006050"}
{"pmid": "21006049", "title": "The use of penicillinase in cultures of body fluids obtained from patients under treatment with penicillin.", "content": "The use of penicillinase in cultures of body fluids obtained from patients under treatment with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006049"}
{"pmid": "21006048", "title": "Hydrometrocolpos in infancy, a cause of urinary retention, intestinal obstruction and edema of the lower extremities.", "content": "Hydrometrocolpos in infancy, a cause of urinary retention, intestinal obstruction and edema of the lower extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006048"}
{"pmid": "21006051", "title": "Infectious mononucleosis; an analysis of 26 clinical and 340 subclinical cases.", "content": "Infectious mononucleosis; an analysis of 26 clinical and 340 subclinical cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006051"}
{"pmid": "21006052", "title": "A comparison in man of sulfathiazole and 2-sulfanilyl-3-5 dihydrothiazole (sulfathiazoline, sulfahydrothiazole).", "content": "A comparison in man of sulfathiazole and 2-sulfanilyl-3-5 dihydrothiazole (sulfathiazoline, sulfahydrothiazole).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006052"}
{"pmid": "21006053", "title": "Treatment of hyperthyroidism with a combination of iodine, thiourea in small doses, and desiccated thyroid.", "content": "Treatment of hyperthyroidism with a combination of iodine, thiourea in small doses, and desiccated thyroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006053"}
{"pmid": "21006054", "title": "Protest; a recorded psychiatric program.", "content": "Protest; a recorded psychiatric program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006054"}
{"pmid": "21006055", "title": "Uterine bleeding and extragenital disturbances.", "content": "Uterine bleeding and extragenital disturbances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006055"}
{"pmid": "21006056", "title": "Congenital hemolytic anemia; a review of progress.", "content": "Congenital hemolytic anemia; a review of progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006056"}
{"pmid": "21006057", "title": "Venereal disease control in the USSR.", "content": "Venereal disease control in the USSR.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006057"}
{"pmid": "21006058", "title": "Bismuth in the treatment of syphilis.", "content": "Bismuth in the treatment of syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006058"}
{"pmid": "21006059", "title": "Intracardiac blood transfusion.", "content": "Intracardiac blood transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006059"}
{"pmid": "21006060", "title": "The struggle against malaria.", "content": "The struggle against malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006060"}
{"pmid": "21006061", "title": "A fulminating form of tertian malaria.", "content": "A fulminating form of tertian malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006061"}
{"pmid": "21006062", "title": "Agglutination of erythrocytes by influenza virus.", "content": "Agglutination of erythrocytes by influenza virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006062"}
{"pmid": "21006063", "title": "Agglutination of erythrocytes by grippe (influenza) virus.", "content": "Agglutination of erythrocytes by grippe (influenza) virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006063"}
{"pmid": "21006064", "title": "Subcutaneous anavaccine VIEM for dysentery.", "content": "Subcutaneous anavaccine VIEM for dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006064"}
{"pmid": "21006065", "title": "The Ixodidae ticks of western Siberia as reservoirs of tularemia.", "content": "The Ixodidae ticks of western Siberia as reservoirs of tularemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006065"}
{"pmid": "21006066", "title": "Problems of wound sepsis.", "content": "Problems of wound sepsis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006066"}
{"pmid": "21006067", "title": "Agonal states and clinical death; problems in revival of organisms.", "content": "Agonal states and clinical death; problems in revival of organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006067"}
{"pmid": "21006068", "title": "Current tasks of public health.", "content": "Current tasks of public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006068"}
{"pmid": "21006069", "title": "Health service in Bashkiria in wartime.", "content": "Health service in Bashkiria in wartime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006069"}
{"pmid": "21006070", "title": "Treatment of burns.", "content": "Treatment of burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006070"}
{"pmid": "21006071", "title": "Treatment of thromboangiitis obliterans.", "content": "Treatment of thromboangiitis obliterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006071"}
{"pmid": "21006072", "title": "Indian village obstetric emergencies.", "content": "Indian village obstetric emergencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006072"}
{"pmid": "21006073", "title": "My experience with the patients treated in the Famine Relief Hospital, Balisai, Midnapore District, Bengal.", "content": "My experience with the patients treated in the Famine Relief Hospital, Balisai, Midnapore District, Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006073"}
{"pmid": "21006074", "title": "Indian medicines in fevers.", "content": "Indian medicines in fevers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006074"}
{"pmid": "21006075", "title": "Modern treatment of gonorrhea.", "content": "Modern treatment of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006075"}
{"pmid": "21006076", "title": "Angioneurotic edema.", "content": "Angioneurotic edema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006076"}
{"pmid": "21006077", "title": "Malaria and its Oriental treatment.", "content": "Malaria and its Oriental treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006077"}
{"pmid": "21006079", "title": "Spa treatment of rheumatic diseases in the United States; representative spas.", "content": "Spa treatment of rheumatic diseases in the United States; representative spas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006079"}
{"pmid": "21006078", "title": "A complicated case of eclampsia.", "content": "A complicated case of eclampsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006078"}
{"pmid": "21006080", "title": "A critique of the use of rest in the physical therapy of convalescence.", "content": "A critique of the use of rest in the physical therapy of convalescence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006080"}
{"pmid": "21006081", "title": "Artificial fever-chemotherapy; maintenance period.", "content": "Artificial fever-chemotherapy; maintenance period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006081"}
{"pmid": "21006082", "title": "Physical therapy as an adjunct to artificial fever in brucellosis.", "content": "Physical therapy as an adjunct to artificial fever in brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006082"}
{"pmid": "21006083", "title": "The physiology of exercise in relation to physical medicine.", "content": "The physiology of exercise in relation to physical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006083"}
{"pmid": "21006084", "title": "Pressure pavex treatment of varicose ulcers and stasis of extremities.", "content": "Pressure pavex treatment of varicose ulcers and stasis of extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006084"}
{"pmid": "21006085", "title": "Effect of ultraviolet radiation on physical fitness.", "content": "Effect of ultraviolet radiation on physical fitness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006085"}
{"pmid": "21006086", "title": "Poliomyelitis equipment.", "content": "Poliomyelitis equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006086"}
{"pmid": "21006087", "title": "Suggestions on immobilization of the hand.", "content": "Suggestions on immobilization of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006087"}
{"pmid": "21006088", "title": "Work therapy in an Army general hospital.", "content": "Work therapy in an Army general hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006088"}
{"pmid": "21006089", "title": "The challenge of crutches; prescribing crutch gaits for orthopedic disabilities.", "content": "The challenge of crutches; prescribing crutch gaits for orthopedic disabilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006089"}
{"pmid": "21006090", "title": "New uses of procains; preliminary communication.", "content": "New uses of procains; preliminary communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006090"}
{"pmid": "21006091", "title": "Exercising device for increasing joint action.", "content": "Exercising device for increasing joint action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006091"}
{"pmid": "21006092", "title": "Stockinet-adhesive chest strapping.", "content": "Stockinet-adhesive chest strapping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006092"}
{"pmid": "21006093", "title": "Physical medicine in the Army Air Forces convalescent hospital.", "content": "Physical medicine in the Army Air Forces convalescent hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006093"}
{"pmid": "21006094", "title": "Support of fingers and thumb in radial nerve paralysis.", "content": "Support of fingers and thumb in radial nerve paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006094"}
{"pmid": "21006095", "title": "Natural resistance against diphtheria toxin.", "content": "Natural resistance against diphtheria toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006095"}
{"pmid": "21006096", "title": "Studies on the detoxication of toxins; catalytic breakdown of crystalline ovalbumin.", "content": "Studies on the detoxication of toxins; catalytic breakdown of crystalline ovalbumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006096"}
{"pmid": "21006097", "title": "Partial dissociation of haemagglutinin and infective activity of Newcastle disease virus.", "content": "Partial dissociation of haemagglutinin and infective activity of Newcastle disease virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006097"}
{"pmid": "21006098", "title": "Experiments on the elution of Newcastle disease virus and influenza virus from fowl red cells.", "content": "Experiments on the elution of Newcastle disease virus and influenza virus from fowl red cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006098"}
{"pmid": "21006099", "title": "The process of virus neutralization as observed in haemagglutination experiments.", "content": "The process of virus neutralization as observed in haemagglutination experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006099"}
{"pmid": "21006100", "title": "The action of human tears on influenza virus.", "content": "The action of human tears on influenza virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006100"}
{"pmid": "21006101", "title": "Agglutination of pigeon erythrocytes in influenza virus A in the 0 phase.", "content": "Agglutination of pigeon erythrocytes in influenza virus A in the 0 phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006101"}
{"pmid": "21006102", "title": "Further notes on a lytic phenomenon shown by group B streptococci.", "content": "Further notes on a lytic phenomenon shown by group B streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006102"}
{"pmid": "21006103", "title": "The influence of temperature, humidity and density on the oviposition of the small strain of Calandra oryzae L. and Rhizopertha dominica Fab (Coleoptera).", "content": "The influence of temperature, humidity and density on the oviposition of the small strain of Calandra oryzae L. and Rhizopertha dominica Fab (Coleoptera).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006103"}
{"pmid": "21006104", "title": "The action of halogens on influenza virus with special reference to the action of iodine vapour on virus mists.", "content": "The action of halogens on influenza virus with special reference to the action of iodine vapour on virus mists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006104"}
{"pmid": "21006105", "title": "The estimation of nucleic-acid phosphorus in plant material.", "content": "The estimation of nucleic-acid phosphorus in plant material.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006105"}
{"pmid": "21006106", "title": "On the rate of inactivation of tobacco mosaic virus by potassium salicylate.", "content": "On the rate of inactivation of tobacco mosaic virus by potassium salicylate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006106"}
{"pmid": "21006107", "title": "The tyrosine and tryptophane contents of some legume seed proteins.", "content": "The tyrosine and tryptophane contents of some legume seed proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006107"}
{"pmid": "21006108", "title": "Anti-coagulant activity of diluted blood perfused through the lung.", "content": "Anti-coagulant activity of diluted blood perfused through the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006108"}
{"pmid": "21006109", "title": "The effects of infection of tobacco plants (Nicotiana tabacum) with tobacco mosaic virus on some of the properties of the protein present in the leaves.", "content": "The effects of infection of tobacco plants (Nicotiana tabacum) with tobacco mosaic virus on some of the properties of the protein present in the leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006109"}
{"pmid": "21006110", "title": "Heparine evaluation.", "content": "Heparine evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006110"}
{"pmid": "21006111", "title": "The metabolism of starving leaves; nitrogen balance sheet and changes in organic acid content during starvation of oat leaves.", "content": "The metabolism of starving leaves; nitrogen balance sheet and changes in organic acid content during starvation of oat leaves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006111"}
{"pmid": "21006112", "title": "A survey of fungous diseases in Great Britain; results from the first eighteen months.", "content": "A survey of fungous diseases in Great Britain; results from the first eighteen months.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006112"}
{"pmid": "21006113", "title": "Treatment of acute appendicitis; a study of 480 consecutive cases.", "content": "Treatment of acute appendicitis; a study of 480 consecutive cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006113"}
{"pmid": "21006114", "title": "Heavy nupercaine spinal analgesia in operative obstetrics; with report of 394 cases.", "content": "Heavy nupercaine spinal analgesia in operative obstetrics; with report of 394 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006114"}
{"pmid": "21006115", "title": "Bladder-neck obstruction due to non-malignant disease of the prostate.", "content": "Bladder-neck obstruction due to non-malignant disease of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006115"}
{"pmid": "21006116", "title": "Paradoxical embolism; with report of a case due to a ventricular septum defect.", "content": "Paradoxical embolism; with report of a case due to a ventricular septum defect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006116"}
{"pmid": "21006117", "title": "Actinomycosis successfully treated with penicillin; report of two cases.", "content": "Actinomycosis successfully treated with penicillin; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006117"}
{"pmid": "21006118", "title": "Torsion of omentum.", "content": "Torsion of omentum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006118"}
{"pmid": "21006120", "title": "WILL there be an influenza epidemic?", "content": "WILL there be an influenza epidemic?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006120"}
{"pmid": "21006119", "title": "Heated carrier for transporting premature babies.", "content": "Heated carrier for transporting premature babies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006119"}
{"pmid": "21006121", "title": "Morphine as a prophylactic against ileus.", "content": "Morphine as a prophylactic against ileus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006121"}
{"pmid": "21006122", "title": "Surgical catgut.", "content": "Surgical catgut.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006122"}
{"pmid": "21006123", "title": "The Renaissance and its influence on English medicine, surgery, and public health.", "content": "The Renaissance and its influence on English medicine, surgery, and public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006123"}
{"pmid": "21006125", "title": "Ear disease in children.", "content": "Ear disease in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006125"}
{"pmid": "21006124", "title": "Prevention of homologous serum jaundice.", "content": "Prevention of homologous serum jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006124"}
{"pmid": "21006126", "title": "Poisoning due to mobilization of lead from the skeleton by leukaemic hyperplasia of bone marrow.", "content": "Poisoning due to mobilization of lead from the skeleton by leukaemic hyperplasia of bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006126"}
{"pmid": "21006127", "title": "A case of chronic undermining ulceration treated with penicillin.", "content": "A case of chronic undermining ulceration treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006127"}
{"pmid": "21006128", "title": "Reaction to penicillin.", "content": "Reaction to penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006128"}
{"pmid": "21006129", "title": "A simple apparatus for penicillin administration.", "content": "A simple apparatus for penicillin administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006129"}
{"pmid": "21006130", "title": "Tropical medicine in war and peace.", "content": "Tropical medicine in war and peace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006130"}
{"pmid": "21006131", "title": "Histoplasmosis; a summary of the known facts about the disease; report of a case.", "content": "Histoplasmosis; a summary of the known facts about the disease; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006131"}
{"pmid": "21006132", "title": "Pulmonary manifestations of brucellosis; report of a case.", "content": "Pulmonary manifestations of brucellosis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006132"}
{"pmid": "21006133", "title": "A case of metastatic carcinoma simulating the Guillain-Barre syndrome.", "content": "A case of metastatic carcinoma simulating the Guillain-Barre syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006133"}
{"pmid": "21006134", "title": "Vascular injuries in battle casualties.", "content": "Vascular injuries in battle casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006134"}
{"pmid": "21006135", "title": "The alteration of kidney circulation and function resulting from complete renal ischemia and hemorrhagic shock.", "content": "The alteration of kidney circulation and function resulting from complete renal ischemia and hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006135"}
{"pmid": "21006136", "title": "Congenital polycystic disease of the kidneys; case report.", "content": "Congenital polycystic disease of the kidneys; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006136"}
{"pmid": "21006137", "title": "Penicillin for local application.", "content": "Penicillin for local application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006137"}
{"pmid": "21006138", "title": "Hallux rigidus causing intermittent limping.", "content": "Hallux rigidus causing intermittent limping.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006138"}
{"pmid": "21006139", "title": "Malaria in the European and in the African patient.", "content": "Malaria in the European and in the African patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006139"}
{"pmid": "21006140", "title": "The treatment of fractures of the shafts of the radius and the ulna; with clinical notes on 5 cases.", "content": "The treatment of fractures of the shafts of the radius and the ulna; with clinical notes on 5 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006140"}
{"pmid": "21006141", "title": "The health and nutritional status of the 124 poor European children 6-7 years of age.", "content": "The health and nutritional status of the 124 poor European children 6-7 years of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006141"}
{"pmid": "21006142", "title": "[Fused kidney].", "content": "[Fused kidney].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006142"}
{"pmid": "21006144", "title": "The roentgen ray: its past and future.", "content": "The roentgen ray: its past and future.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006144"}
{"pmid": "21006143", "title": "Introduction.", "content": "Introduction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006143"}
{"pmid": "21006153", "title": "Inter-American cooperation in medicine.", "content": "Inter-American cooperation in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006153"}
{"pmid": "21006155", "title": "Transmission of poliomyelitis by patient to patient contact.", "content": "Transmission of poliomyelitis by patient to patient contact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006155"}
{"pmid": "21006156", "title": "Treatment of preparalytic poliomyelitis with gamma globulin.", "content": "Treatment of preparalytic poliomyelitis with gamma globulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006156"}
{"pmid": "21006157", "title": "A study of the origin of an epidemic of poliomyelitis.", "content": "A study of the origin of an epidemic of poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006157"}
{"pmid": "21006154", "title": "The penicillin treatment of subacute bacterial endocarditis.", "content": "The penicillin treatment of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006154"}
{"pmid": "21006159", "title": "Insomnia due to left ventricular heart failure unrecognized as such and inadequately treated.", "content": "Insomnia due to left ventricular heart failure unrecognized as such and inadequately treated.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006159"}
{"pmid": "21006146", "title": "Roentgen treatment for Hodgkin's disease and lymphosarcoma of the chest.", "content": "Roentgen treatment for Hodgkin's disease and lymphosarcoma of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006146"}
{"pmid": "21006158", "title": "Effect of exercise on blood pressure of patients with advanced hypertension before and after thoracolumbar sympathectomy.", "content": "Effect of exercise on blood pressure of patients with advanced hypertension before and after thoracolumbar sympathectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006158"}
{"pmid": "21006160", "title": "The treatment of spotted fever with para-aminobenzoic acid.", "content": "The treatment of spotted fever with para-aminobenzoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006160"}
{"pmid": "21006145", "title": "The segments of the lungs; a commentary on their investigation and morbid radiology.", "content": "The segments of the lungs; a commentary on their investigation and morbid radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006145"}
{"pmid": "21006147", "title": "Length and width changes in the pulmonary arterial system of rabbits in passing from the stage of expiration to that of collapse as revealed by roentgenography.", "content": "Length and width changes in the pulmonary arterial system of rabbits in passing from the stage of expiration to that of collapse as revealed by roentgenography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006147"}
{"pmid": "21006161", "title": "Opportunities for the medically trained in public health.", "content": "Opportunities for the medically trained in public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006161"}
{"pmid": "21006162", "title": "Actinomycotic granuloma of the stomach.", "content": "Actinomycotic granuloma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006162"}
{"pmid": "21006151", "title": "Neurogenic tumors at the pulmonary apex.", "content": "Neurogenic tumors at the pulmonary apex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006151"}
{"pmid": "21006148", "title": "The lateral projection of the chest.", "content": "The lateral projection of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006148"}
{"pmid": "21006163", "title": "Complication arising from use of vitallium tube for common duct repair.", "content": "Complication arising from use of vitallium tube for common duct repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006163"}
{"pmid": "21006164", "title": "Ultraviolet lamps for disinfecting purposes; present status.", "content": "Ultraviolet lamps for disinfecting purposes; present status.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006164"}
{"pmid": "21006152", "title": "Intrathoracic metallic foreign bodies.", "content": "Intrathoracic metallic foreign bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006152"}
{"pmid": "21006150", "title": "The bearers of shadows.", "content": "The bearers of shadows.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006150"}
{"pmid": "21006149", "title": "Clinical value of angiocardiography.", "content": "Clinical value of angiocardiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006149"}
{"pmid": "21006165", "title": "Chemical compounds with inhibitory effect in hyperthyroidism.", "content": "Chemical compounds with inhibitory effect in hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006165"}
{"pmid": "21006166", "title": "Treatment of the agonal state and of clinical death.", "content": "Treatment of the agonal state and of clinical death.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006166"}
{"pmid": "21006167", "title": "Paroxysmal abdominal pain; a form of focal symptomatic epilepsy.", "content": "Paroxysmal abdominal pain; a form of focal symptomatic epilepsy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006167"}
{"pmid": "21006168", "title": "Clinical trials with quinine-epinephrine intravenously.", "content": "Clinical trials with quinine-epinephrine intravenously.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006168"}
{"pmid": "21006169", "title": "Clinical tetanus; a study of 56 cases, with special reference to methods of prevention and a plan for evaluating treatment.", "content": "Clinical tetanus; a study of 56 cases, with special reference to methods of prevention and a plan for evaluating treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006169"}
{"pmid": "21006170", "title": "The treatment of early syphilis with penicillin.", "content": "The treatment of early syphilis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006170"}
{"pmid": "21006171", "title": "An effective method for the control of trichinosis in the United States.", "content": "An effective method for the control of trichinosis in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006171"}
{"pmid": "21006173", "title": "Safety of modern alternating positive and negative pressure resuscitators.", "content": "Safety of modern alternating positive and negative pressure resuscitators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006173"}
{"pmid": "21006172", "title": "Accidental intra-arterial injection of oxophenarsine hydrochloride (mapharsen).", "content": "Accidental intra-arterial injection of oxophenarsine hydrochloride (mapharsen).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006172"}
{"pmid": "21006174", "title": "Injections of distilled water.", "content": "Injections of distilled water.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006174"}
{"pmid": "21006175", "title": "Determination of Rh factor.", "content": "Determination of Rh factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006175"}
{"pmid": "21006177", "title": "Hepatolenticular degeneration.", "content": "Hepatolenticular degeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006177"}
{"pmid": "21006176", "title": "Protective skin coatings for the prevention of sunburn.", "content": "Protective skin coatings for the prevention of sunburn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006176"}
{"pmid": "21006178", "title": "Malaria therapy in syphilitic primary optic atrophy.", "content": "Malaria therapy in syphilitic primary optic atrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006178"}
{"pmid": "21006179", "title": "Shiga dysentery.", "content": "Shiga dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006179"}
{"pmid": "21006180", "title": "Parathyroid adenoma and hypertrophy of the parathyroid glands.", "content": "Parathyroid adenoma and hypertrophy of the parathyroid glands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006180"}
{"pmid": "21006181", "title": "Foreign body (case knife) in the sigmoid.", "content": "Foreign body (case knife) in the sigmoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006181"}
{"pmid": "21006182", "title": "DEPARTMENT of Medicine and Surgery in the Veterans Administration.", "content": "DEPARTMENT of Medicine and Surgery in the Veterans Administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006182"}
{"pmid": "21006183", "title": "Recurrent headache resultant from malaria.", "content": "Recurrent headache resultant from malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006183"}
{"pmid": "21006184", "title": "The influence of cholene cystine, and of alpha-tocopherol upon the occurrence of ceroid pigment in dietary cirrhosis of rats.", "content": "The influence of cholene cystine, and of alpha-tocopherol upon the occurrence of ceroid pigment in dietary cirrhosis of rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006184"}
{"pmid": "21006185", "title": "Studies on the biochemical, biophysical, and immunogenic properties of Japanese B type encephalitis virus and vaccines.", "content": "Studies on the biochemical, biophysical, and immunogenic properties of Japanese B type encephalitis virus and vaccines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006185"}
{"pmid": "21006186", "title": "Plasma protein metabolism; electrophoretic studies; the influence of plasma lipids on electrophoretic patterns of human and dog plasma.", "content": "Plasma protein metabolism; electrophoretic studies; the influence of plasma lipids on electrophoretic patterns of human and dog plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006186"}
{"pmid": "21006188", "title": "Prevention of pneumococcal pneumonia by immunization with specific capsular polysaccharides.", "content": "Prevention of pneumococcal pneumonia by immunization with specific capsular polysaccharides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006188"}
{"pmid": "21006187", "title": "Enduring immunity following vaccination of mice with formalin-inactivated virus of Russian spring-summer (Far Eastern, tick-borne) encephalitis; correlation with serum-neutralizing and complement-fixing antibodies.", "content": "Enduring immunity following vaccination of mice with formalin-inactivated virus of Russian spring-summer (Far Eastern, tick-borne) encephalitis; correlation with serum-neutralizing and complement-fixing antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006187"}
{"pmid": "21006189", "title": "The role of the pediatrician and the general practitioner in the diagnosis and treatment of behavior problems in children.", "content": "The role of the pediatrician and the general practitioner in the diagnosis and treatment of behavior problems in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006189"}
{"pmid": "21006190", "title": "Infectious mononucleosis; typhoid type.", "content": "Infectious mononucleosis; typhoid type.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006190"}
{"pmid": "21006191", "title": "Choice of anaesthetic.", "content": "Choice of anaesthetic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006191"}
{"pmid": "21006192", "title": "The electrocardiogram; history and clinical application.", "content": "The electrocardiogram; history and clinical application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006192"}
{"pmid": "21006193", "title": "Enuresis.", "content": "Enuresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006193"}
{"pmid": "21006194", "title": "Marion Sims and other 19th pioneers; the dawn of scientific medicine and surgery.", "content": "Marion Sims and other 19th pioneers; the dawn of scientific medicine and surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006194"}
{"pmid": "21006208", "title": "The hazards of bed rest.", "content": "The hazards of bed rest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006208"}
{"pmid": "21006209", "title": "Unilateral agenesis of the kidney with double kidney and uretrocele on the opposite side and genital anomalies.", "content": "Unilateral agenesis of the kidney with double kidney and uretrocele on the opposite side and genital anomalies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006209"}
{"pmid": "21006210", "title": "Vital staining and its applications.", "content": "Vital staining and its applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006210"}
{"pmid": "21006211", "title": "Analgesia and anesthesia in obstetrics.", "content": "Analgesia and anesthesia in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006211"}
{"pmid": "21006212", "title": "Insecticides and repellents in modern medicine.", "content": "Insecticides and repellents in modern medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006212"}
{"pmid": "21006213", "title": "The histological picture of cerebral oedema.", "content": "The histological picture of cerebral oedema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006213"}
{"pmid": "21006214", "title": "Gas gangrene.", "content": "Gas gangrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006214"}
{"pmid": "21006215", "title": "A superficial description of myocardial metabolism.", "content": "A superficial description of myocardial metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006215"}
{"pmid": "21006216", "title": "Concepts in constitution.", "content": "Concepts in constitution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006216"}
{"pmid": "21006217", "title": "Malarial immunity.", "content": "Malarial immunity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006217"}
{"pmid": "21006218", "title": "A speculation on nerve impulse mediation.", "content": "A speculation on nerve impulse mediation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006218"}
{"pmid": "21006219", "title": "Rheumatic recrudescences in children.", "content": "Rheumatic recrudescences in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006219"}
{"pmid": "21006220", "title": "Penicillin in the treatment of empyema thoracis; report of two cases.", "content": "Penicillin in the treatment of empyema thoracis; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006220"}
{"pmid": "21006221", "title": "The problem of premature mortality.", "content": "The problem of premature mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006221"}
{"pmid": "21006222", "title": "The diagnosis and treatment of acute abdominal conditions in children.", "content": "The diagnosis and treatment of acute abdominal conditions in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006222"}
{"pmid": "21006223", "title": "Herpes zoster.", "content": "Herpes zoster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006223"}
{"pmid": "21006224", "title": "Sulphaguanidine, sulphathiazole and extract of suprarenal cortex in the treatment of cholera.", "content": "Sulphaguanidine, sulphathiazole and extract of suprarenal cortex in the treatment of cholera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006224"}
{"pmid": "21006225", "title": "The treatment of acute gonorrhea in the Army.", "content": "The treatment of acute gonorrhea in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006225"}
{"pmid": "21006226", "title": "Pyrexial reactions after transfusions and injections; their causes, prevention and treatment.", "content": "Pyrexial reactions after transfusions and injections; their causes, prevention and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006226"}
{"pmid": "21006227", "title": "Occupational dermatoses; disability and compensation.", "content": "Occupational dermatoses; disability and compensation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006227"}
{"pmid": "21006228", "title": "The development of anatomical laws in the states of New England.", "content": "The development of anatomical laws in the states of New England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006228"}
{"pmid": "21006229", "title": "Infectious mononucleosis.", "content": "Infectious mononucleosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006229"}
{"pmid": "21006230", "title": "Stone at bifurcation of common hepatic duct.", "content": "Stone at bifurcation of common hepatic duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006230"}
{"pmid": "21006231", "title": "Tuberculosis of tongue, epiglottis, larynx, lungs, testes, epididymes, prostate, bladder and left kidney.", "content": "Tuberculosis of tongue, epiglottis, larynx, lungs, testes, epididymes, prostate, bladder and left kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006231"}
{"pmid": "21006232", "title": "Annular areas of pulmonary rarefaction in children.", "content": "Annular areas of pulmonary rarefaction in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006232"}
{"pmid": "21006233", "title": "Some principles of genetics.", "content": "Some principles of genetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006233"}
{"pmid": "21006234", "title": "Appraisal of the nutritional status of children.", "content": "Appraisal of the nutritional status of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006234"}
{"pmid": "21006235", "title": "Rheumatic heart disease; a study of 167 cases among 12,317 autopsies performed at the Charity Hospital in New Orleans during 10 years.", "content": "Rheumatic heart disease; a study of 167 cases among 12,317 autopsies performed at the Charity Hospital in New Orleans during 10 years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006235"}
{"pmid": "21006236", "title": "Hemolytic anemia of the newborn (erythroblastosis fetalis) report of cases.", "content": "Hemolytic anemia of the newborn (erythroblastosis fetalis) report of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006236"}
{"pmid": "21006237", "title": "Fatal Mediterranean (Cooley's) anemia.", "content": "Fatal Mediterranean (Cooley's) anemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006237"}
{"pmid": "21006239", "title": "Hypertrophic pyloric stenosis (analysis of 37 cases at Charity Hospital).", "content": "Hypertrophic pyloric stenosis (analysis of 37 cases at Charity Hospital).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006239"}
{"pmid": "21006238", "title": "Some psychologic hazards in the adoption of a child.", "content": "Some psychologic hazards in the adoption of a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006238"}
{"pmid": "21006240", "title": "Acute laryngotracheobronchitis vs. diphtheria.", "content": "Acute laryngotracheobronchitis vs. diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006240"}
{"pmid": "21006282", "title": "The clinical use of streptomycin.", "content": "The clinical use of streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006282"}
{"pmid": "21006283", "title": "Protection in roentgenoscopy.", "content": "Protection in roentgenoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006283"}
{"pmid": "21006284", "title": "Parenteral administration of gelatin.", "content": "Parenteral administration of gelatin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006284"}
{"pmid": "21006285", "title": "Transurethral surgery in 1944.", "content": "Transurethral surgery in 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006285"}
{"pmid": "21006286", "title": "Calculation of the rate of absorption of exogenous creatinine.", "content": "Calculation of the rate of absorption of exogenous creatinine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006286"}
{"pmid": "21006287", "title": "Effect of pyridoxine on granulopenia caused by thiouracil.", "content": "Effect of pyridoxine on granulopenia caused by thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006287"}
{"pmid": "21006291", "title": "Prevention of formation of end-bulb neuromata.", "content": "Prevention of formation of end-bulb neuromata.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006291"}
{"pmid": "21006289", "title": "Alloxan diabetes in rabbits; production of hypercholesterolemia, hyperlipemia and adrenal cortical lesions.", "content": "Alloxan diabetes in rabbits; production of hypercholesterolemia, hyperlipemia and adrenal cortical lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006289"}
{"pmid": "21006292", "title": "Vaginal response to adrenal stimulation.", "content": "Vaginal response to adrenal stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006292"}
{"pmid": "21006290", "title": "Horse brain thromboplastin; effect of various factors on activity of horse brain extracts.", "content": "Horse brain thromboplastin; effect of various factors on activity of horse brain extracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006290"}
{"pmid": "21006293", "title": "Effect of thiouracil on growing swine.", "content": "Effect of thiouracil on growing swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006293"}
{"pmid": "21006288", "title": "Experimental tumors after nerve section in an insect.", "content": "Experimental tumors after nerve section in an insect.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006288"}
{"pmid": "21006294", "title": "No androgen in corn pollen.", "content": "No androgen in corn pollen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006294"}
{"pmid": "21006295", "title": "Incidence of the eight Rh types among 179 white Puerto Ricans.", "content": "Incidence of the eight Rh types among 179 white Puerto Ricans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006295"}
{"pmid": "21006297", "title": "Cause of an outbreak of encephalitis established by means of complement-fixation tests.", "content": "Cause of an outbreak of encephalitis established by means of complement-fixation tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006297"}
{"pmid": "21006296", "title": "Influence of sulfonamides and para-aminobenzoic acid on the growth of Lupinus albus.", "content": "Influence of sulfonamides and para-aminobenzoic acid on the growth of Lupinus albus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006296"}
{"pmid": "21006299", "title": "The porphyrin of Harder's gland.", "content": "The porphyrin of Harder's gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006299"}
{"pmid": "21006298", "title": "Observations on antimicrobial action of 2,3-dichloro-1,4-naphthoquinone, and its reversal by vitamin K.", "content": "Observations on antimicrobial action of 2,3-dichloro-1,4-naphthoquinone, and its reversal by vitamin K.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006298"}
{"pmid": "21006300", "title": "Serological differentiation of primary atypical pneumonia from virus pneumonia of the psittacosis group.", "content": "Serological differentiation of primary atypical pneumonia from virus pneumonia of the psittacosis group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006300"}
{"pmid": "21006301", "title": "Experimental intestinal myiasis in man.", "content": "Experimental intestinal myiasis in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006301"}
{"pmid": "21006302", "title": "Impedance changes in the cerebrum following concussion.", "content": "Impedance changes in the cerebrum following concussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006302"}
{"pmid": "21006303", "title": "Growth of corpus luteum in rats during pregnancy and following injections of testosterone.", "content": "Growth of corpus luteum in rats during pregnancy and following injections of testosterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006303"}
{"pmid": "21006304", "title": "Comparison of the cephalin-cholesterol flocculation with the thymol turbidity test.", "content": "Comparison of the cephalin-cholesterol flocculation with the thymol turbidity test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006304"}
{"pmid": "21006305", "title": "Blood sugar level and autonomic balance.", "content": "Blood sugar level and autonomic balance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006305"}
{"pmid": "21006306", "title": "Dietary requirements for fertility and lactation; rice and its by-products as sources of pyridoxine and pantothenic acid for reproduction and lactation.", "content": "Dietary requirements for fertility and lactation; rice and its by-products as sources of pyridoxine and pantothenic acid for reproduction and lactation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006306"}
{"pmid": "21006307", "title": "Effects of prolonged irradiation of mice with fluorescent light.", "content": "Effects of prolonged irradiation of mice with fluorescent light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006307"}
{"pmid": "21006308", "title": "Comparison of the golden hamster with the guinea pig following inoculations of virulent tubercle bacilli.", "content": "Comparison of the golden hamster with the guinea pig following inoculations of virulent tubercle bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006308"}
{"pmid": "21006309", "title": "Relation of plasma level of atabrine to morphology and motility of Plasmodium vivax.", "content": "Relation of plasma level of atabrine to morphology and motility of Plasmodium vivax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006309"}
{"pmid": "21006311", "title": "Plasma protein concentrations in adrenalectomized rats maintained on sodium chloride.", "content": "Plasma protein concentrations in adrenalectomized rats maintained on sodium chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006311"}
{"pmid": "21006310", "title": "Treatment of sprue with synthetic L. casei factor (folic acid, vitamin M).", "content": "Treatment of sprue with synthetic L. casei factor (folic acid, vitamin M).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006310"}
{"pmid": "21006313", "title": "Occurrence of thiaminase in marine teleosts.", "content": "Occurrence of thiaminase in marine teleosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006313"}
{"pmid": "21006312", "title": "The sensory and motor axons of the chorda tympani.", "content": "The sensory and motor axons of the chorda tympani.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006312"}
{"pmid": "21006314", "title": "Utilization of certain rare sugars by microorganisms.", "content": "Utilization of certain rare sugars by microorganisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006314"}
{"pmid": "21006315", "title": "Metabolism of methyl and benzyl esters of penicillin by different species.", "content": "Metabolism of methyl and benzyl esters of penicillin by different species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006315"}
{"pmid": "21006317", "title": "Influence of pyridoxine, inositol, and biotin on susceptibility of Swiss mice to experimental poliomyelitis.", "content": "Influence of pyridoxine, inositol, and biotin on susceptibility of Swiss mice to experimental poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006317"}
{"pmid": "21006316", "title": "Renal hyperlipemia in dogs and rats.", "content": "Renal hyperlipemia in dogs and rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006316"}
{"pmid": "21006318", "title": "The relative toxicity of l- and dl-serine in rats.", "content": "The relative toxicity of l- and dl-serine in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006318"}
{"pmid": "21006320", "title": "Colorimetric estimation of penicillin in aqueous solutions.", "content": "Colorimetric estimation of penicillin in aqueous solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006320"}
{"pmid": "21006322", "title": "Brain abscess and meningitis caused by a diphtheroid resembling Corynebacterium ulcerogenes.", "content": "Brain abscess and meningitis caused by a diphtheroid resembling Corynebacterium ulcerogenes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006322"}
{"pmid": "21006323", "title": "Fumaric acid salts as hydrogogue cathartics.", "content": "Fumaric acid salts as hydrogogue cathartics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006323"}
{"pmid": "21006325", "title": "Poliomyelitis.", "content": "Poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006325"}
{"pmid": "21006321", "title": "Renal clearance of beta-hydroxybutyric acid in a dog.", "content": "Renal clearance of beta-hydroxybutyric acid in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006321"}
{"pmid": "21006329", "title": "Case of pneumonia with acetone body acidosis.", "content": "Case of pneumonia with acetone body acidosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006329"}
{"pmid": "21006326", "title": "Secondary arteriosclerosis of pulmonary arteries with thrombosis.", "content": "Secondary arteriosclerosis of pulmonary arteries with thrombosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006326"}
{"pmid": "21006319", "title": "Variations of some constituents in the urine of rats receiving dl-serine and dl-alanine.", "content": "Variations of some constituents in the urine of rats receiving dl-serine and dl-alanine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006319"}
{"pmid": "21006324", "title": "A method for consistent induction of chronic hyperglycemia with alloxan.", "content": "A method for consistent induction of chronic hyperglycemia with alloxan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006324"}
{"pmid": "21006328", "title": "Large gangrenous submucous myoma in vagina.", "content": "Large gangrenous submucous myoma in vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006328"}
{"pmid": "21006330", "title": "Congenital telangiectasis.", "content": "Congenital telangiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006330"}
{"pmid": "21006327", "title": "Case of intracranial neoplasm.", "content": "Case of intracranial neoplasm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006327"}
{"pmid": "21006331", "title": "Autopsy report; case of a 42 year old molder suffering from a severe headache of six weeks duration. 93. [Torula meningo-encephalitis and silico-tuberculosis].", "content": "Autopsy report; case of a 42 year old molder suffering from a severe headache of six weeks duration. 93. [Torula meningo-encephalitis and silico-tuberculosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006331"}
{"pmid": "21006350", "title": "The crunch syndrome; review with case report.", "content": "The crunch syndrome; review with case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006350"}
{"pmid": "21006351", "title": "The trend of medicine toward socialization.", "content": "The trend of medicine toward socialization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006351"}
{"pmid": "21006352", "title": "Developments in the Medical College of Alabama.", "content": "Developments in the Medical College of Alabama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006352"}
{"pmid": "21006353", "title": "Post-war plan for training naval medical officers.", "content": "Post-war plan for training naval medical officers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006353"}
{"pmid": "21006354", "title": "Reconversion of the doctor from war to peace.", "content": "Reconversion of the doctor from war to peace.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006354"}
{"pmid": "21006355", "title": "Food and health in Great Britain during the war.", "content": "Food and health in Great Britain during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006355"}
{"pmid": "21006356", "title": "Types of circulatory failure.", "content": "Types of circulatory failure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006356"}
{"pmid": "21006357", "title": "The effect of folic acid on sprue.", "content": "The effect of folic acid on sprue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006357"}
{"pmid": "21006358", "title": "Disturbances in lipid metabolism in children.", "content": "Disturbances in lipid metabolism in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006358"}
{"pmid": "21006359", "title": "Newer methods of hemostasis in neurosurgery.", "content": "Newer methods of hemostasis in neurosurgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006359"}
{"pmid": "21006360", "title": "Modern treatment of mucocele of the frontal and ethmoidal sinuses.", "content": "Modern treatment of mucocele of the frontal and ethmoidal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006360"}
{"pmid": "21006361", "title": "Ectopic pregnancy.", "content": "Ectopic pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006361"}
{"pmid": "21006362", "title": "Principles of penicillin therapy.", "content": "Principles of penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006362"}
{"pmid": "21006363", "title": "The treatment of Streptococcus viridans endocarditis with penicillin.", "content": "The treatment of Streptococcus viridans endocarditis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006363"}
{"pmid": "21006364", "title": "Does the fractional daily urine examination on a diabetic patient furnish us the ideal means of control?", "content": "Does the fractional daily urine examination on a diabetic patient furnish us the ideal means of control?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006364"}
{"pmid": "21006365", "title": "Observations on the treatment of diabetes mellitus complicated by pulmonary tuberculosis.", "content": "Observations on the treatment of diabetes mellitus complicated by pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006365"}
{"pmid": "21006366", "title": "Ten years experience with an operation for the cure of certain types of sexual impotence.", "content": "Ten years experience with an operation for the cure of certain types of sexual impotence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006366"}
{"pmid": "21006375", "title": "[The results of the conference of the leading workers of evacuo-hospitals of the People's Commissariat of Public Health of the RSFSR].", "content": "[The results of the conference of the leading workers of evacuo-hospitals of the People's Commissariat of Public Health of the RSFSR].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006375"}
{"pmid": "21006376", "title": "[A year of the work of the Commission of the Military Hospital Committee on the cadres' improvement].", "content": "[A year of the work of the Commission of the Military Hospital Committee on the cadres' improvement].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006376"}
{"pmid": "21006377", "title": "[On the sanitary-instructive work in evacuo-hospitals].", "content": "[On the sanitary-instructive work in evacuo-hospitals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006377"}
{"pmid": "21006378", "title": "[How the story of the N... evacuo-hospital was written].", "content": "[How the story of the N... evacuo-hospital was written].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006378"}
{"pmid": "21006379", "title": "[Secondary hemorrhages and prevention of complications following the ligature of the arterial trunks and great blood losses].", "content": "[Secondary hemorrhages and prevention of complications following the ligature of the arterial trunks and great blood losses].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006379"}
{"pmid": "21006380", "title": "[The role of chemical factors in the nervous excitation of trophic ulcers].", "content": "[The role of chemical factors in the nervous excitation of trophic ulcers].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006380"}
{"pmid": "21006381", "title": "[The treatment of non-closing wounds, ulcers and contractures by means of grafting of the chemically worked-up tissue after Krause].", "content": "[The treatment of non-closing wounds, ulcers and contractures by means of grafting of the chemically worked-up tissue after Krause].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006381"}
{"pmid": "21006382", "title": "[Secondary suture of granulating wounds].", "content": "[Secondary suture of granulating wounds].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006382"}
{"pmid": "21006383", "title": "[Clinics of complications and the treatment of gunshot wounds of the upper extremities].", "content": "[Clinics of complications and the treatment of gunshot wounds of the upper extremities].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006383"}
{"pmid": "21006384", "title": "[On the extension of indications for amputation and exarticulation of the fingers].", "content": "[On the extension of indications for amputation and exarticulation of the fingers].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006384"}
{"pmid": "21006368", "title": "Organic lesions resulting from emotional stress.", "content": "Organic lesions resulting from emotional stress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006368"}
{"pmid": "21006370", "title": "Tularemia; report of six cases of tick borne origin.", "content": "Tularemia; report of six cases of tick borne origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006370"}
{"pmid": "21006372", "title": "Postpartum sterilization.", "content": "Postpartum sterilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006372"}
{"pmid": "21006385", "title": "[Muscular plastics in chronic osteomyelitis].", "content": "[Muscular plastics in chronic osteomyelitis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006385"}
{"pmid": "21006373", "title": "A survey of tuberculosis observed at Freeman Clinic from 1934 to 1944 and related statistics.", "content": "A survey of tuberculosis observed at Freeman Clinic from 1934 to 1944 and related statistics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006373"}
{"pmid": "21006374", "title": "The diagnosis and treatment of ocular neuroses.", "content": "The diagnosis and treatment of ocular neuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006374"}
{"pmid": "21006367", "title": "Should our doctors be regimented?", "content": "Should our doctors be regimented?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006367"}
{"pmid": "21006371", "title": "Injury to the colon from air hose inflation.", "content": "Injury to the colon from air hose inflation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006371"}
{"pmid": "21006387", "title": "[A crutch with an amortizator].", "content": "[A crutch with an amortizator].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006387"}
{"pmid": "21006388", "title": "[A new method of preparation of the surgeon's hands].", "content": "[A new method of preparation of the surgeon's hands].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006388"}
{"pmid": "21006389", "title": "[A new method for renewal of dressing material].", "content": "[A new method for renewal of dressing material].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006389"}
{"pmid": "21006390", "title": "[An oven for the autoclave].", "content": "[An oven for the autoclave].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006390"}
{"pmid": "21006369", "title": "Penicillin in the treatment of congenital syphilis.", "content": "Penicillin in the treatment of congenital syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006369"}
{"pmid": "21006391", "title": "[A needle of continuous action].", "content": "[A needle of continuous action].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006391"}
{"pmid": "21006394", "title": "[A rule for drawing off plaster bandages].", "content": "[A rule for drawing off plaster bandages].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006394"}
{"pmid": "21006392", "title": "[Experiment with employment of hydrolysate of the blood as a substitute for pepton].", "content": "[Experiment with employment of hydrolysate of the blood as a substitute for pepton].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006392"}
{"pmid": "21006395", "title": "[Some experience in the work with medical cadres in the care of public health].", "content": "[Some experience in the work with medical cadres in the care of public health].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006395"}
{"pmid": "21006393", "title": "[Sterilization of silk with aqueous solution of iodine].", "content": "[Sterilization of silk with aqueous solution of iodine].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006393"}
{"pmid": "21006397", "title": "[Statistical illustrations in the histories of evacuo-hospitals].", "content": "[Statistical illustrations in the histories of evacuo-hospitals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006397"}
{"pmid": "21006396", "title": "[On dissertations of the physicians of evacuo-hospitals].", "content": "[On dissertations of the physicians of evacuo-hospitals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006396"}
{"pmid": "21006386", "title": "[Conservation of blood with addition of white streptocide].", "content": "[Conservation of blood with addition of white streptocide].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006386"}
{"pmid": "21006398", "title": "[Analysis of the issues in the therapeutical department of the N... evacuo-hospital].", "content": "[Analysis of the issues in the therapeutical department of the N... evacuo-hospital].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006398"}
{"pmid": "21006399", "title": "[Concerning certain misinterpretations in the setting of medical physical culture in hospitals].", "content": "[Concerning certain misinterpretations in the setting of medical physical culture in hospitals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006399"}
{"pmid": "21006400", "title": "[Pain syndrome in injuries of the peripheral nerves and its treatment].", "content": "[Pain syndrome in injuries of the peripheral nerves and its treatment].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006400"}
{"pmid": "21006401", "title": "[Sulfide preparations as a new effective medicinal factor in certain skin diseases].", "content": "[Sulfide preparations as a new effective medicinal factor in certain skin diseases].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006401"}
{"pmid": "21006403", "title": "[Pathogenesis and therapy of wound eczema].", "content": "[Pathogenesis and therapy of wound eczema].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006403"}
{"pmid": "21006402", "title": "[The treatment with naphthalene of osteomyelitis of tubular bones following gunshot lesions].", "content": "[The treatment with naphthalene of osteomyelitis of tubular bones following gunshot lesions].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006402"}
{"pmid": "21006404", "title": "[On the technics of the removal of a magnetic splinters from the laminae of the cornea].", "content": "[On the technics of the removal of a magnetic splinters from the laminae of the cornea].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006404"}
{"pmid": "21006406", "title": "[Photographing from the roentgen screen (fluorography, screenography)].", "content": "[Photographing from the roentgen screen (fluorography, screenography)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006406"}
{"pmid": "21006405", "title": "[Dormant infection; its discrimination and treatment].", "content": "[Dormant infection; its discrimination and treatment].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006405"}
{"pmid": "21006408", "title": "[The value of the roentgenological sign of clear border for determination of locus of a metallic foreign body in the bone tissue].", "content": "[The value of the roentgenological sign of clear border for determination of locus of a metallic foreign body in the bone tissue].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006408"}
{"pmid": "21006407", "title": "[A modification of Carrel's vascular suture].", "content": "[A modification of Carrel's vascular suture].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006407"}
{"pmid": "21006409", "title": "[The basic errors of physicians in purulent surgery].", "content": "[The basic errors of physicians in purulent surgery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006409"}
{"pmid": "21006410", "title": "[Preparing the medical history of the present war in England and America].", "content": "[Preparing the medical history of the present war in England and America].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006410"}
{"pmid": "21006411", "title": "[On the efficiency of sorting and profiling the wounded and sick].", "content": "[On the efficiency of sorting and profiling the wounded and sick].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006411"}
{"pmid": "21006412", "title": "[Some analysis of the work of K.E.H.].", "content": "[Some analysis of the work of K.E.H.].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006412"}
{"pmid": "21006413", "title": "[Additional sources of nourishment and their rational utilization].", "content": "[Additional sources of nourishment and their rational utilization].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006413"}
{"pmid": "21006414", "title": "[On administration of hypertonic plasma in shock following acute blood losses].", "content": "[On administration of hypertonic plasma in shock following acute blood losses].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006414"}
{"pmid": "21006415", "title": "[On the roentgendiagnosis of postwound hemothorax].", "content": "[On the roentgendiagnosis of postwound hemothorax].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006415"}
{"pmid": "21006416", "title": "[Concerning the treatment of subcapital closed gunshot fractures of the femoral collum at evacuo-hospitals].", "content": "[Concerning the treatment of subcapital closed gunshot fractures of the femoral collum at evacuo-hospitals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006416"}
{"pmid": "21006418", "title": "[The treatment of wounds not closing for a long time].", "content": "[The treatment of wounds not closing for a long time].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006418"}
{"pmid": "21006417", "title": "[Concerning gunshot osteomyelitis].", "content": "[Concerning gunshot osteomyelitis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006417"}
{"pmid": "21006419", "title": "[On technique of tissue transplantation].", "content": "[On technique of tissue transplantation].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006419"}
{"pmid": "21006420", "title": "[The treatment of infected wounds with gramicidine C].", "content": "[The treatment of infected wounds with gramicidine C].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006420"}
{"pmid": "21006421", "title": "[The clinics and treatment of war injuries in the region of cauda equina].", "content": "[The clinics and treatment of war injuries in the region of cauda equina].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006421"}
{"pmid": "21006423", "title": "[A deodorizing bandage].", "content": "[A deodorizing bandage].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006423"}
{"pmid": "21006422", "title": "[Urolithiasis as a complication of war trauma].", "content": "[Urolithiasis as a complication of war trauma].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006422"}
{"pmid": "21006424", "title": "[Our method for the transportation of conserved blood].", "content": "[Our method for the transportation of conserved blood].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006424"}
{"pmid": "21006425", "title": "[Early reamputation].", "content": "[Early reamputation].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006425"}
{"pmid": "21006426", "title": "[On forgotten foreign bodies].", "content": "[On forgotten foreign bodies].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006426"}
{"pmid": "21006427", "title": "[The treatment of injuries to the extensor of the finger].", "content": "[The treatment of injuries to the extensor of the finger].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006427"}
{"pmid": "21006428", "title": "Operating room procedures.", "content": "Operating room procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006428"}
{"pmid": "21006429", "title": "Anesthesia.", "content": "Anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006429"}
{"pmid": "21006430", "title": "Medical records section.", "content": "Medical records section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006430"}
{"pmid": "21006431", "title": "Use of DDT in the field.", "content": "Use of DDT in the field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006431"}
{"pmid": "21006432", "title": "Rehabilitation can be fun.", "content": "Rehabilitation can be fun.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006432"}
{"pmid": "21006434", "title": "Surgery on the mess table.", "content": "Surgery on the mess table.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006434"}
{"pmid": "21006433", "title": "Wire screen fly traps.", "content": "Wire screen fly traps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006433"}
{"pmid": "21006435", "title": "An improved finger splint.", "content": "An improved finger splint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006435"}
{"pmid": "21006436", "title": "Army support for collecting blood.", "content": "Army support for collecting blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006436"}
{"pmid": "21006437", "title": "Fly prevention; some suggestions and observations from a general hospital in Normandy, 1944.", "content": "Fly prevention; some suggestions and observations from a general hospital in Normandy, 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006437"}
{"pmid": "21006438", "title": "Experiences as an officer in medical charge of British prisoners of war in Italy and Germany.", "content": "Experiences as an officer in medical charge of British prisoners of war in Italy and Germany.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006438"}
{"pmid": "21006439", "title": "Notes on air evacuation.", "content": "Notes on air evacuation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006439"}
{"pmid": "21006440", "title": "Notes on a mule born A.D.S.", "content": "Notes on a mule born A.D.S.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006440"}
{"pmid": "21006441", "title": "Mule transport by forward surgical units.", "content": "Mule transport by forward surgical units.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006441"}
{"pmid": "21006443", "title": "Surgery in advance of roadhead.", "content": "Surgery in advance of roadhead.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006443"}
{"pmid": "21006442", "title": "A mobile dressing post.", "content": "A mobile dressing post.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006442"}
{"pmid": "21006444", "title": "The N.C.O. as a psychiatric casualty; a study of 627 cases admitted to a psychiatric hospital.", "content": "The N.C.O. as a psychiatric casualty; a study of 627 cases admitted to a psychiatric hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006444"}
{"pmid": "21006445", "title": "An epidemic of scrub typhus.", "content": "An epidemic of scrub typhus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006445"}
{"pmid": "21006446", "title": "Field nephritis in the German army.", "content": "Field nephritis in the German army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006446"}
{"pmid": "21006448", "title": "RAT-BITE fever.", "content": "RAT-BITE fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006448"}
{"pmid": "21006447", "title": "PROGRESS against influenza.", "content": "PROGRESS against influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006447"}
{"pmid": "21006449", "title": "DENGUE and perverted taste.", "content": "DENGUE and perverted taste.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006449"}
{"pmid": "21006450", "title": "Major difficulties experienced in the establishment of 600 and 1,200 bed hospitals in Normandy.", "content": "Major difficulties experienced in the establishment of 600 and 1,200 bed hospitals in Normandy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006450"}
{"pmid": "21006451", "title": "The subcutaneous administration of penicillin.", "content": "The subcutaneous administration of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006451"}
{"pmid": "21006452", "title": "The management of convalescent soldiers.", "content": "The management of convalescent soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006452"}
{"pmid": "21006453", "title": "Culture methods in the diagnosis of amoebiasis.", "content": "Culture methods in the diagnosis of amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006453"}
{"pmid": "21006454", "title": "Neuroparalytic accident following anti-rabic vaccination.", "content": "Neuroparalytic accident following anti-rabic vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006454"}
{"pmid": "21006456", "title": "An aerodynamic suit for the protection of pilots against black-out.", "content": "An aerodynamic suit for the protection of pilots against black-out.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006456"}
{"pmid": "21006455", "title": "Investigation of the fungistatic activity of reagents that might be suitable for use in the treatment of epidermophytosis.", "content": "Investigation of the fungistatic activity of reagents that might be suitable for use in the treatment of epidermophytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006455"}
{"pmid": "21006457", "title": "The scientist's interference with the things he studies.", "content": "The scientist's interference with the things he studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006457"}
{"pmid": "21006458", "title": "AUSTRALIAN activities in the field of human nutrition.", "content": "AUSTRALIAN activities in the field of human nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006458"}
{"pmid": "21006479", "title": "TEAM work in science.", "content": "TEAM work in science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006479"}
{"pmid": "21006480", "title": "The teaching of analytical chemistry in Great Britain: with special reference to microchemistry.", "content": "The teaching of analytical chemistry in Great Britain: with special reference to microchemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006480"}
{"pmid": "21006481", "title": "New basic concepts in electrocardiography; the ventricular gradient.", "content": "New basic concepts in electrocardiography; the ventricular gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006481"}
{"pmid": "21006482", "title": "3:4-benzpyrene from coal tar.", "content": "3:4-benzpyrene from coal tar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006482"}
{"pmid": "21006483", "title": "Concentration of solutions of salts of penicillin.", "content": "Concentration of solutions of salts of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006483"}
{"pmid": "21006484", "title": "Sexual differentiation of the gonad and the sexualization of the germ cells in teleosts.", "content": "Sexual differentiation of the gonad and the sexualization of the germ cells in teleosts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006484"}
{"pmid": "21006485", "title": "British anti-lewisite (BAL).", "content": "British anti-lewisite (BAL).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006485"}
{"pmid": "21006486", "title": "Antimalarial activity in tetrahydroacridones and related substances.", "content": "Antimalarial activity in tetrahydroacridones and related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006486"}
{"pmid": "21006487", "title": "Crystallization and identity of the triose and triosephosphate dehydrogenases of muscle.", "content": "Crystallization and identity of the triose and triosephosphate dehydrogenases of muscle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006487"}
{"pmid": "21006488", "title": "Molecular morphology of myosin.", "content": "Molecular morphology of myosin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006488"}
{"pmid": "21006489", "title": "Heat coagulation of muscle proteins.", "content": "Heat coagulation of muscle proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006489"}
{"pmid": "21006490", "title": "Activity of helvolic acid against Mycobacterium tuberculosis.", "content": "Activity of helvolic acid against Mycobacterium tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006490"}
{"pmid": "21006491", "title": "An illusion of size.", "content": "An illusion of size.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006491"}
{"pmid": "21006492", "title": "THE UNITY of science.", "content": "THE UNITY of science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006492"}
{"pmid": "21006493", "title": "Effective and ineffective strains of legume nodule bacteria.", "content": "Effective and ineffective strains of legume nodule bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006493"}
{"pmid": "21006495", "title": "Transition of fibrinogen to fibrin as a two-step reaction.", "content": "Transition of fibrinogen to fibrin as a two-step reaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006495"}
{"pmid": "21006494", "title": "Enhancement of the action of immune haem-agglutinins by human serum.", "content": "Enhancement of the action of immune haem-agglutinins by human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006494"}
{"pmid": "21006496", "title": "The anti-chromatic reflex.", "content": "The anti-chromatic reflex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006496"}
{"pmid": "21006497", "title": "Studies on Oxytricha bifaria Stokes; cystic reorganization.", "content": "Studies on Oxytricha bifaria Stokes; cystic reorganization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006497"}
{"pmid": "21006498", "title": "Supernucleate cysts of Endamoeba coli and E. histolytica.", "content": "Supernucleate cysts of Endamoeba coli and E. histolytica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006498"}
{"pmid": "21006500", "title": "The composition of the refractive bodies in the rhizopod Pelomyxa carolinensis.", "content": "The composition of the refractive bodies in the rhizopod Pelomyxa carolinensis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006500"}
{"pmid": "21006499", "title": "A quantitative method for the determination of the amebacidal activity of drugs in vitro.", "content": "A quantitative method for the determination of the amebacidal activity of drugs in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006499"}
{"pmid": "21006501", "title": "Studies on monogenetic trematodes; Urocleidus seculus, a new species of Tetraonchinae from the viviparous top minnow, Gambusia affinis affinis (Baird and Girard).", "content": "Studies on monogenetic trematodes; Urocleidus seculus, a new species of Tetraonchinae from the viviparous top minnow, Gambusia affinis affinis (Baird and Girard).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006501"}
{"pmid": "21006502", "title": "Two trematodes from a hibernating bat, Myotis californicus.", "content": "Two trematodes from a hibernating bat, Myotis californicus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006502"}
{"pmid": "21006503", "title": "A new genus of monogenetic trematode from Bermuda.", "content": "A new genus of monogenetic trematode from Bermuda.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006503"}
{"pmid": "21006504", "title": "A new hymenolepidid cestode, Hymenolepis furcouterina, from a Celebesian black-bellied snakebird.", "content": "A new hymenolepidid cestode, Hymenolepis furcouterina, from a Celebesian black-bellied snakebird.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006504"}
{"pmid": "21006505", "title": "Collection and preservation of sandflies (Phlebotomus) with keys to U.S. species (Diptera: Psychodidae).", "content": "Collection and preservation of sandflies (Phlebotomus) with keys to U.S. species (Diptera: Psychodidae).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006505"}
{"pmid": "21006507", "title": "Disturbances in sleep mechanism; a clinicopathologic study; lesions at the corticodiencephalic level.", "content": "Disturbances in sleep mechanism; a clinicopathologic study; lesions at the corticodiencephalic level.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006507"}
{"pmid": "21006506", "title": "Acute war neurosis; special reference to Pavlov's experimental observations and the mechanism of abreaction.", "content": "Acute war neurosis; special reference to Pavlov's experimental observations and the mechanism of abreaction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006506"}
{"pmid": "21006508", "title": "Multiplicity of representation versus punctate localization in the motor cortex.", "content": "Multiplicity of representation versus punctate localization in the motor cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006508"}
{"pmid": "21006509", "title": "Disseminated oligodendroglioma.", "content": "Disseminated oligodendroglioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006509"}
{"pmid": "21006510", "title": "Blood supply of peripheral nerves; practical considerations.", "content": "Blood supply of peripheral nerves; practical considerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006510"}
{"pmid": "21006511", "title": "Blood supply of the sciatic nerve and its popliteal divisions in man.", "content": "Blood supply of the sciatic nerve and its popliteal divisions in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006511"}
{"pmid": "21006512", "title": "Studies on cerebral edema; reaction of the brain to exposure to air; physiologic changes.", "content": "Studies on cerebral edema; reaction of the brain to exposure to air; physiologic changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006512"}
{"pmid": "21006514", "title": "Common factors precipitating mental symptoms.", "content": "Common factors precipitating mental symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006514"}
{"pmid": "21006513", "title": "Experimental study on treatment of dementia paralytica with penicillin.", "content": "Experimental study on treatment of dementia paralytica with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006513"}
{"pmid": "21006515", "title": "Hysterical convulsions treated with hypnosis and psychotherapy; report of a case.", "content": "Hysterical convulsions treated with hypnosis and psychotherapy; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006515"}
{"pmid": "21006516", "title": "Use of galvanic tetanus and the galvanic tetanus ratios in electrodiagnosis of lesions of peripheral nerves.", "content": "Use of galvanic tetanus and the galvanic tetanus ratios in electrodiagnosis of lesions of peripheral nerves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006516"}
{"pmid": "21006517", "title": "The use of psychoanalytic principles in the therapeutic management of an acute psychosis.", "content": "The use of psychoanalytic principles in the therapeutic management of an acute psychosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006517"}
{"pmid": "21006518", "title": "Short psychoanalytic psychotherapy.", "content": "Short psychoanalytic psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006518"}
{"pmid": "21006520", "title": "Reminiscent notes on the early history of psycho-analysis in English-speaking countries.", "content": "Reminiscent notes on the early history of psycho-analysis in English-speaking countries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006520"}
{"pmid": "21006519", "title": "Dostoevsky and parricide.", "content": "Dostoevsky and parricide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006519"}
{"pmid": "21006522", "title": "The concept of trauma in contemporary psycho-analytical theory.", "content": "The concept of trauma in contemporary psycho-analytical theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006522"}
{"pmid": "21006521", "title": "The Oedipus complex in the light of early anxieties.", "content": "The Oedipus complex in the light of early anxieties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006521"}
{"pmid": "21006523", "title": "The unconscious origin of Schopenhauer's philosophy.", "content": "The unconscious origin of Schopenhauer's philosophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006523"}
{"pmid": "21006524", "title": "A note on ambivalence.", "content": "A note on ambivalence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006524"}
{"pmid": "21006525", "title": "Notes on metapsychology as process theory; some comments.", "content": "Notes on metapsychology as process theory; some comments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006525"}
{"pmid": "21006526", "title": "Some psychological aspects of prostitution; the pseudo-personality.", "content": "Some psychological aspects of prostitution; the pseudo-personality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006526"}
{"pmid": "21006527", "title": "The treatment of the psychotic-like regressions of the combat soldier.", "content": "The treatment of the psychotic-like regressions of the combat soldier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006527"}
{"pmid": "21006528", "title": "True and false conceptions of psychoanalysis.", "content": "True and false conceptions of psychoanalysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006528"}
{"pmid": "21006529", "title": "The treatment of psychoses with methyl guanidine sulfate; a clinical report of 12 cases.", "content": "The treatment of psychoses with methyl guanidine sulfate; a clinical report of 12 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006529"}
{"pmid": "21006530", "title": "Archetype postures; clinical impressions.", "content": "Archetype postures; clinical impressions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006530"}
{"pmid": "21006532", "title": "Posthospitalization supportive psychotherapy.", "content": "Posthospitalization supportive psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006532"}
{"pmid": "21006533", "title": "The clinical measurement of anxiety; an experimental approach.", "content": "The clinical measurement of anxiety; an experimental approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006533"}
{"pmid": "21006531", "title": "Schizophrenic-like reactions in children. II.", "content": "Schizophrenic-like reactions in children. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006531"}
{"pmid": "21006534", "title": "Psychiatric implications of internal medicine.", "content": "Psychiatric implications of internal medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006534"}
{"pmid": "21006535", "title": "Prevalence of pulmonary tuberculosis in New York State institutions for the mentally ill.", "content": "Prevalence of pulmonary tuberculosis in New York State institutions for the mentally ill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006535"}
{"pmid": "21006536", "title": "A short genetic survey of psychic impotence. II.", "content": "A short genetic survey of psychic impotence. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006536"}
{"pmid": "21006537", "title": "A comparison of the Wechsler-Bellevue and the revised Stanford-Binet scales for adult defective delinquents.", "content": "A comparison of the Wechsler-Bellevue and the revised Stanford-Binet scales for adult defective delinquents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006537"}
{"pmid": "21006539", "title": "Further observations on hallucinations of small.", "content": "Further observations on hallucinations of small.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006539"}
{"pmid": "21006540", "title": "Institutionalizing the obsessive psychopath.", "content": "Institutionalizing the obsessive psychopath.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006540"}
{"pmid": "21006538", "title": "The anticonvulsant action of tridione; preliminary report.", "content": "The anticonvulsant action of tridione; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006538"}
{"pmid": "21006542", "title": "Nursing and nursing education in Germany.", "content": "Nursing and nursing education in Germany.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006542"}
{"pmid": "21006541", "title": "Postwar trends in public health and nursing.", "content": "Postwar trends in public health and nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006541"}
{"pmid": "21006543", "title": "Nursing aboard a hospital ship.", "content": "Nursing aboard a hospital ship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006543"}
{"pmid": "21006546", "title": "Opinion molders appraise nursing.", "content": "Opinion molders appraise nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006546"}
{"pmid": "21006544", "title": "Health program for radium dial workers.", "content": "Health program for radium dial workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006544"}
{"pmid": "21006551", "title": "31,000 Army nurses and their postwar plans.", "content": "31,000 Army nurses and their postwar plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006551"}
{"pmid": "21006545", "title": "One blueprint for recruitment.", "content": "One blueprint for recruitment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006545"}
{"pmid": "21006547", "title": "The Marianas.", "content": "The Marianas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006547"}
{"pmid": "21006550", "title": "5,000 Civilian nurses.", "content": "5,000 Civilian nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006550"}
{"pmid": "21006548", "title": "They pioneered on Tinian.", "content": "They pioneered on Tinian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006548"}
{"pmid": "21006549", "title": "Return to the Philippines.", "content": "Return to the Philippines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006549"}
{"pmid": "21006553", "title": "The child on a Bradford frame; diversional therapy.", "content": "The child on a Bradford frame; diversional therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006553"}
{"pmid": "21006552", "title": "Combined immunization against whooping cough, diphtheria, and tetanus.", "content": "Combined immunization against whooping cough, diphtheria, and tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006552"}
{"pmid": "21006555", "title": "Convalescent care of children.", "content": "Convalescent care of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006555"}
{"pmid": "21006554", "title": "The U.S. Cadet Nurse Corps; a summing up.", "content": "The U.S. Cadet Nurse Corps; a summing up.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006554"}
{"pmid": "21006557", "title": "Every nurse has a share in the war on cancer.", "content": "Every nurse has a share in the war on cancer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006557"}
{"pmid": "21006558", "title": "Food handling instructions for nurses.", "content": "Food handling instructions for nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006558"}
{"pmid": "21006556", "title": "Insulin therapy in combat exhaustion.", "content": "Insulin therapy in combat exhaustion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006556"}
{"pmid": "21006559", "title": "Dentritic keratitis associated with chronic malaria.", "content": "Dentritic keratitis associated with chronic malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006559"}
{"pmid": "21006561", "title": "Allergic retinosis.", "content": "Allergic retinosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006561"}
{"pmid": "21006560", "title": "A comparative study of the bacteriologic flora of nasal and nasopharyngeal membranes of patients with certain ocular disorders.", "content": "A comparative study of the bacteriologic flora of nasal and nasopharyngeal membranes of patients with certain ocular disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006560"}
{"pmid": "21006564", "title": "Restoration of patency of the nasolacrimal duct by means of a vitallium tube; a preliminary report.", "content": "Restoration of patency of the nasolacrimal duct by means of a vitallium tube; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006564"}
{"pmid": "21006562", "title": "Statistical analysis of 1,000 consecutive new eye patients.", "content": "Statistical analysis of 1,000 consecutive new eye patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006562"}
{"pmid": "21006563", "title": "A method for the extraction of dislocated lenses from the vitreous.", "content": "A method for the extraction of dislocated lenses from the vitreous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006563"}
{"pmid": "21006565", "title": "Experiences with the surgery of the anophthalmic orbit.", "content": "Experiences with the surgery of the anophthalmic orbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006565"}
{"pmid": "21006567", "title": "A new model of contact glass for gonioscopy (goniolens).", "content": "A new model of contact glass for gonioscopy (goniolens).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006567"}
{"pmid": "21006566", "title": "Megalocornea.", "content": "Megalocornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006566"}
{"pmid": "21006570", "title": "Familial corneal dystrophy; three cases.", "content": "Familial corneal dystrophy; three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006570"}
{"pmid": "21006569", "title": "Hinge-flap sclerotomy drainage operations.", "content": "Hinge-flap sclerotomy drainage operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006569"}
{"pmid": "21006571", "title": "Loose flocculus in anterior chamber.", "content": "Loose flocculus in anterior chamber.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006571"}
{"pmid": "21006568", "title": "Ocular sensitivity to butyn.", "content": "Ocular sensitivity to butyn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006568"}
{"pmid": "21006573", "title": "Mikulicz's disease.", "content": "Mikulicz's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006573"}
{"pmid": "21006572", "title": "Hereditary anterior megalophthalmos.", "content": "Hereditary anterior megalophthalmos.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006572"}
{"pmid": "21006574", "title": "Detachment of the retina.", "content": "Detachment of the retina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006574"}
{"pmid": "21006576", "title": "Atypical coloboma of the choroid.", "content": "Atypical coloboma of the choroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006576"}
{"pmid": "21006575", "title": "Sphenoidal-ridge meningioma en plaque.", "content": "Sphenoidal-ridge meningioma en plaque.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006575"}
{"pmid": "21006577", "title": "Detachment of retina with multiple tears.", "content": "Detachment of retina with multiple tears.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006577"}
{"pmid": "21006578", "title": "Thrombosis of retinal vein treated with dicumarol.", "content": "Thrombosis of retinal vein treated with dicumarol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006578"}
{"pmid": "21006581", "title": "Cyst of the iris.", "content": "Cyst of the iris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006581"}
{"pmid": "21006580", "title": "Fusion in esotropia without orthoptic training.", "content": "Fusion in esotropia without orthoptic training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006580"}
{"pmid": "21006579", "title": "Plastic repair for cicatricial stenosis of the lacrimal canaliculi.", "content": "Plastic repair for cicatricial stenosis of the lacrimal canaliculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006579"}
{"pmid": "21006582", "title": "Syphilitic iritis with particular reference to the Herxheimer reaction as a diagnostic aid and response to different treatment including penicillin.", "content": "Syphilitic iritis with particular reference to the Herxheimer reaction as a diagnostic aid and response to different treatment including penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006582"}
{"pmid": "21006583", "title": "Commonly used ophthalmic drugs of little value.", "content": "Commonly used ophthalmic drugs of little value.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006583"}
{"pmid": "21006584", "title": "The Graf Wiser technique in the treatment of refractive abnormalities.", "content": "The Graf Wiser technique in the treatment of refractive abnormalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006584"}
{"pmid": "21006587", "title": "A physicist's summary of atomic energy.", "content": "A physicist's summary of atomic energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006587"}
{"pmid": "21006586", "title": "Lighting and safety.", "content": "Lighting and safety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006586"}
{"pmid": "21006585", "title": "Defective color vision in a female patient; a case report.", "content": "Defective color vision in a female patient; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006585"}
{"pmid": "21006590", "title": "A case of occipital lobe injury.", "content": "A case of occipital lobe injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006590"}
{"pmid": "21006589", "title": "Ocular gnathostomiasis.", "content": "Ocular gnathostomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006589"}
{"pmid": "21006588", "title": "Ocular manifestations of malnutrition in released prisoners of war from Thailand.", "content": "Ocular manifestations of malnutrition in released prisoners of war from Thailand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006588"}
{"pmid": "21006591", "title": "Indirect injury of the optic chiasma; a case report.", "content": "Indirect injury of the optic chiasma; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006591"}
{"pmid": "21006592", "title": "Retinal haemorrhages in aplastic anaemia.", "content": "Retinal haemorrhages in aplastic anaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006592"}
{"pmid": "21006593", "title": "Haemorrhage from the conjunctiva; notes on a case of capillary angioma.", "content": "Haemorrhage from the conjunctiva; notes on a case of capillary angioma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006593"}
{"pmid": "21006594", "title": "A corneal graft operation for recurrent pterygium.", "content": "A corneal graft operation for recurrent pterygium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006594"}
{"pmid": "21006595", "title": "Coppock cataract and cataracta pulverulenta centralis.", "content": "Coppock cataract and cataracta pulverulenta centralis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006595"}
{"pmid": "21006596", "title": "Diabetic needles.", "content": "Diabetic needles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006596"}
{"pmid": "21006597", "title": "MEMORANDUM on the notification and certification of the blind, on definitions of blindness, and on blind pensions.", "content": "MEMORANDUM on the notification and certification of the blind, on definitions of blindness, and on blind pensions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006597"}
{"pmid": "21006598", "title": "Report from the Wilmer Institute on the results obtained in the treatment of myopia by visual training.", "content": "Report from the Wilmer Institute on the results obtained in the treatment of myopia by visual training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006598"}
{"pmid": "21006599", "title": "Current problems of myopia.", "content": "Current problems of myopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006599"}
{"pmid": "21006600", "title": "INDUSTRIAL ophthalmology.", "content": "INDUSTRIAL ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006600"}
{"pmid": "21006602", "title": "Conservation of hearing; the Cleveland hearing conservation program.", "content": "Conservation of hearing; the Cleveland hearing conservation program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006602"}
{"pmid": "21006601", "title": "Determining visual standards for industrial jobs by statistical methods.", "content": "Determining visual standards for industrial jobs by statistical methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006601"}
{"pmid": "21006604", "title": "Experimental histological studies on the labyrinth; agonal and post-mortem changes.", "content": "Experimental histological studies on the labyrinth; agonal and post-mortem changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006604"}
{"pmid": "21006603", "title": "Experimental histological studies on the labyrinth.", "content": "Experimental histological studies on the labyrinth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006603"}
{"pmid": "21006605", "title": "Experimental histological studies on the labyrinth; the endolymphatic compression (Wittmaack's hypotonic degeneration).", "content": "Experimental histological studies on the labyrinth; the endolymphatic compression (Wittmaack's hypotonic degeneration).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006605"}
{"pmid": "21006609", "title": "A case of caseous rhinitis and bilateral caseous maxillary sinusitis.", "content": "A case of caseous rhinitis and bilateral caseous maxillary sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006609"}
{"pmid": "21006608", "title": "Hemolytic streptococci in the nose and pharynx; a study on their significance to complications following otorhino-laryngological operations.", "content": "Hemolytic streptococci in the nose and pharynx; a study on their significance to complications following otorhino-laryngological operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006608"}
{"pmid": "21006610", "title": "Investigations in the microphone effect of the cochlea with some remarks on a new technique.", "content": "Investigations in the microphone effect of the cochlea with some remarks on a new technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006610"}
{"pmid": "21006611", "title": "The surgical treatment of otogenous facial paresis.", "content": "The surgical treatment of otogenous facial paresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006611"}
{"pmid": "21006612", "title": "Experimental histological labyrinth examinations.", "content": "Experimental histological labyrinth examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006612"}
{"pmid": "21006613", "title": "A peculiar case of subglottic laryngitis.", "content": "A peculiar case of subglottic laryngitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006613"}
{"pmid": "21006614", "title": "A case of acute suppurative otitis media with tardy occurrence of perisinuous abscess and thrombosis of the sigmoid sinus.", "content": "A case of acute suppurative otitis media with tardy occurrence of perisinuous abscess and thrombosis of the sigmoid sinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006614"}
{"pmid": "21006615", "title": "Foreign bodies in esophagus and air-passages.", "content": "Foreign bodies in esophagus and air-passages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006615"}
{"pmid": "21006616", "title": "Some orienting remarks about tuning-forks and audiometer, and about the registration of defects of hearing.", "content": "Some orienting remarks about tuning-forks and audiometer, and about the registration of defects of hearing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006616"}
{"pmid": "21006617", "title": "Acute suppurative otitis media in infants.", "content": "Acute suppurative otitis media in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006617"}
{"pmid": "21006618", "title": "The material of infant patients with otitis media in the Kommunehospital of Copenhagen.", "content": "The material of infant patients with otitis media in the Kommunehospital of Copenhagen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006618"}
{"pmid": "21006621", "title": "Local sulfathiazole treatment of the wound cavity after mastoidectomy in acute mastoiditis.", "content": "Local sulfathiazole treatment of the wound cavity after mastoidectomy in acute mastoiditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006621"}
{"pmid": "21006619", "title": "Experimental histological studies on the labyrinth; pilocarpine and atropin.", "content": "Experimental histological studies on the labyrinth; pilocarpine and atropin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006619"}
{"pmid": "21006620", "title": "Cases of familial esophagus stricture.", "content": "Cases of familial esophagus stricture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006620"}
{"pmid": "21006622", "title": "Orbital complications following operations on paranasal sinuses.", "content": "Orbital complications following operations on paranasal sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006622"}
{"pmid": "21006625", "title": "Osteomyelitis necroticans faciei.", "content": "Osteomyelitis necroticans faciei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006625"}
{"pmid": "21006624", "title": "Local treatment with sulfathiazole in sinusitis.", "content": "Local treatment with sulfathiazole in sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006624"}
{"pmid": "21006626", "title": "The genesis of typical and atypical cysts of the nasal floor.", "content": "The genesis of typical and atypical cysts of the nasal floor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006626"}
{"pmid": "21006627", "title": "Bilateral perforate nasopalatine communication in the human adult.", "content": "Bilateral perforate nasopalatine communication in the human adult.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006627"}
{"pmid": "21006629", "title": "Results of treatment of carcinoma of the larynx by x-ray at operation.", "content": "Results of treatment of carcinoma of the larynx by x-ray at operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006629"}
{"pmid": "21006628", "title": "The conservative treatment of chronic suppurative otitis media.", "content": "The conservative treatment of chronic suppurative otitis media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006628"}
{"pmid": "21006630", "title": "Interpretative reading as an aid to speech correction, acting, and radio.", "content": "Interpretative reading as an aid to speech correction, acting, and radio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006630"}
{"pmid": "21006632", "title": "The semantic aspects of stuttering in non-stutterers: additional data.", "content": "The semantic aspects of stuttering in non-stutterers: additional data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006632"}
{"pmid": "21006631", "title": "Suggestions for a successful speech correction program in public schools.", "content": "Suggestions for a successful speech correction program in public schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006631"}
{"pmid": "21006633", "title": "On the coliform bacteria of human feces.", "content": "On the coliform bacteria of human feces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006633"}
{"pmid": "21006635", "title": "Studies in hereditary dwarfism in mice; the histology of the anterior pituitary of mice with hereditary adiposity and of dwarf mice with hereditary adiposity.", "content": "Studies in hereditary dwarfism in mice; the histology of the anterior pituitary of mice with hereditary adiposity and of dwarf mice with hereditary adiposity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006635"}
{"pmid": "21006637", "title": "The action of the pituitary gland on the growth of mice shown by parabiosis.", "content": "The action of the pituitary gland on the growth of mice shown by parabiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006637"}
{"pmid": "21006638", "title": "Capsular antigens common to a streptococcus strain and some pneumococcus types.", "content": "Capsular antigens common to a streptococcus strain and some pneumococcus types.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006638"}
{"pmid": "21006639", "title": "Theoretical and practical results from employment of indigo carmine in studies on anaerobic bacteria.", "content": "Theoretical and practical results from employment of indigo carmine in studies on anaerobic bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006639"}
{"pmid": "21006641", "title": "Extensive arterial calcification and cirrhosis of the liver in a newborn infant.", "content": "Extensive arterial calcification and cirrhosis of the liver in a newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006641"}
{"pmid": "21006642", "title": "The Widal reaction in Sonne dysentery.", "content": "The Widal reaction in Sonne dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006642"}
{"pmid": "21006643", "title": "The use of yeast autolysate as activator in the preparation of diphtheria toxin.", "content": "The use of yeast autolysate as activator in the preparation of diphtheria toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006643"}
{"pmid": "21006645", "title": "Histology of the liver in diseases of the stomach.", "content": "Histology of the liver in diseases of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006645"}
{"pmid": "21006644", "title": "Chemical control of the phenol contents of vaccines and serum preparations.", "content": "Chemical control of the phenol contents of vaccines and serum preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006644"}
{"pmid": "21006646", "title": "Studies on methods for protraction of the effect of penicillin.", "content": "Studies on methods for protraction of the effect of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006646"}
{"pmid": "21006647", "title": "Lysis of red blood cells by tissue slices.", "content": "Lysis of red blood cells by tissue slices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006647"}
{"pmid": "21006648", "title": "The arginine, ornithine and carbon dioxide requirements of streptococci (Lancefield group D) and their relation to arginine dihydrolase activity.", "content": "The arginine, ornithine and carbon dioxide requirements of streptococci (Lancefield group D) and their relation to arginine dihydrolase activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006648"}
{"pmid": "21006649", "title": "The effect of sulphanilamide on the arginine and carbon dioxide requirements of streptococci (Lancefield group D).", "content": "The effect of sulphanilamide on the arginine and carbon dioxide requirements of streptococci (Lancefield group D).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006649"}
{"pmid": "21006651", "title": "A new test for the detection of weak and incomplete Rh agglutinins.", "content": "A new test for the detection of weak and incomplete Rh agglutinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006651"}
{"pmid": "21006650", "title": "The examination of rabbit anti-A immune sera produced by means of an artificial A-antigen.", "content": "The examination of rabbit anti-A immune sera produced by means of an artificial A-antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006650"}
{"pmid": "21006652", "title": "Comparative potency of the mammary tumour agent of mice of different genetic constitution.", "content": "Comparative potency of the mammary tumour agent of mice of different genetic constitution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006652"}
{"pmid": "21006653", "title": "Experimental nodular goitre.", "content": "Experimental nodular goitre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006653"}
{"pmid": "21006654", "title": "Measurement of circulating ragweed antigen.", "content": "Measurement of circulating ragweed antigen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006654"}
{"pmid": "21006655", "title": "Quantitative estimation of the absorption of an ingested allergen.", "content": "Quantitative estimation of the absorption of an ingested allergen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006655"}
{"pmid": "21006656", "title": "A quantitative study of the relation of synthetic 3-pentadecyl catechol to hypersensitiveness to Rhus toxicodendron (poison ivy) as shown by the patch test.", "content": "A quantitative study of the relation of synthetic 3-pentadecyl catechol to hypersensitiveness to Rhus toxicodendron (poison ivy) as shown by the patch test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006656"}
{"pmid": "21006657", "title": "Spontaneous mediastinal and subcutaneous emphysema complicating bronchial asthma; report of an additional case and analysis of 25 previously reported cases.", "content": "Spontaneous mediastinal and subcutaneous emphysema complicating bronchial asthma; report of an additional case and analysis of 25 previously reported cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006657"}
{"pmid": "21006658", "title": "Mold allergy; field survey of Philadelphia area.", "content": "Mold allergy; field survey of Philadelphia area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006658"}
{"pmid": "21006659", "title": "Relief of dermographism and other urticarias of histamine origin by a synthetic benzhydryl alkamine ether.", "content": "Relief of dermographism and other urticarias of histamine origin by a synthetic benzhydryl alkamine ether.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006659"}
{"pmid": "21006660", "title": "Contact dermatitis due to contact with chrome 17 per cent steel identification tags of the United States Navy.", "content": "Contact dermatitis due to contact with chrome 17 per cent steel identification tags of the United States Navy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006660"}
{"pmid": "21006661", "title": "ALLERGY to penicillin.", "content": "ALLERGY to penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006661"}
{"pmid": "21006676", "title": "Salicylates in the treatment of rheumatic patients.", "content": "Salicylates in the treatment of rheumatic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006676"}
{"pmid": "21006677", "title": "Children's idiosyncrasies.", "content": "Children's idiosyncrasies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006677"}
{"pmid": "21006678", "title": "Changing trends in diphtheria in San Francisco.", "content": "Changing trends in diphtheria in San Francisco.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006678"}
{"pmid": "21006679", "title": "Gonorrheal vaginitis in children.", "content": "Gonorrheal vaginitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006679"}
{"pmid": "21006680", "title": "The road to rehabilitation; good teamwork by professional workers helps crippled children to lead normal lives.", "content": "The road to rehabilitation; good teamwork by professional workers helps crippled children to lead normal lives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006680"}
{"pmid": "21006681", "title": "Ten years of progress in reducing maternal and infant mortality.", "content": "Ten years of progress in reducing maternal and infant mortality.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006681"}
{"pmid": "21006682", "title": "Century old botanicals.", "content": "Century old botanicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006682"}
{"pmid": "21006683", "title": "The comparative toxicity and effectiveness of scopolamine hydrobromide (C17H21O4N.HBr) and scopolamine aminoxide hydrobromide (C17H21O5N HBr).", "content": "The comparative toxicity and effectiveness of scopolamine hydrobromide (C17H21O4N.HBr) and scopolamine aminoxide hydrobromide (C17H21O5N HBr).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006683"}
{"pmid": "21006684", "title": "Alcohol beverages and genus Homo sapiens.", "content": "Alcohol beverages and genus Homo sapiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006684"}
{"pmid": "21006685", "title": "Proteins come of age.", "content": "Proteins come of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006685"}
{"pmid": "21006686", "title": "Tropical diseases.", "content": "Tropical diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006686"}
{"pmid": "21006687", "title": "PENICILLIN supply and demand.", "content": "PENICILLIN supply and demand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006687"}
{"pmid": "21006688", "title": "Streptomycin.", "content": "Streptomycin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006688"}
{"pmid": "21006689", "title": "The sprue syndrome.", "content": "The sprue syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006689"}
{"pmid": "21006690", "title": "Penicillin lozenges.", "content": "Penicillin lozenges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006690"}
{"pmid": "21006691", "title": "FURTHER studies in penicillin therapy.", "content": "FURTHER studies in penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006691"}
{"pmid": "21006692", "title": "Malt and extract of malt.", "content": "Malt and extract of malt.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006692"}
{"pmid": "21006693", "title": "The drug resources of North West Frontier Province.", "content": "The drug resources of North West Frontier Province.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006693"}
{"pmid": "21006694", "title": "A review of sulphonamide preparations.", "content": "A review of sulphonamide preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006694"}
{"pmid": "21006695", "title": "What shall we do with uranium?", "content": "What shall we do with uranium?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006695"}
{"pmid": "21006696", "title": "The sterilisation of surgical dressings.", "content": "The sterilisation of surgical dressings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006696"}
{"pmid": "21006697", "title": "The effect of cH on humoral stimulation of striated muscle and its application to the chemical control of breathing.", "content": "The effect of cH on humoral stimulation of striated muscle and its application to the chemical control of breathing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006697"}
{"pmid": "21006698", "title": "The beneficial effects of yeast on the cardiac failure of hyperthyroid rats.", "content": "The beneficial effects of yeast on the cardiac failure of hyperthyroid rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006698"}
{"pmid": "21006699", "title": "Growth and hemoglobin production in dogs on purified rations.", "content": "Growth and hemoglobin production in dogs on purified rations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006699"}
{"pmid": "21006700", "title": "Gonadotropic activity of equine gonadotropin in combination with zinc.", "content": "Gonadotropic activity of equine gonadotropin in combination with zinc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006700"}
{"pmid": "21006701", "title": "Liver water and electrolytes in hemorrhagic shock.", "content": "Liver water and electrolytes in hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006701"}
{"pmid": "21006702", "title": "The production of arterial hypertension by chronic renal artery-nerve stimulation.", "content": "The production of arterial hypertension by chronic renal artery-nerve stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006702"}
{"pmid": "21006703", "title": "Functional changes in nerve and muscle after partial denervation.", "content": "Functional changes in nerve and muscle after partial denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006703"}
{"pmid": "21006704", "title": "Blood regeneration in rats deficient in biotin, thiamin or riboflavin.", "content": "Blood regeneration in rats deficient in biotin, thiamin or riboflavin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006704"}
{"pmid": "21006705", "title": "The effect of calcium concentration on prothrombin time.", "content": "The effect of calcium concentration on prothrombin time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006705"}
{"pmid": "21006707", "title": "Biological energy transformation during shock as shown by blood chemistry.", "content": "Biological energy transformation during shock as shown by blood chemistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006707"}
{"pmid": "21006706", "title": "The distribution of phosphorus compounds in the gastrocnemius muscle as influenced by the ageing process.", "content": "The distribution of phosphorus compounds in the gastrocnemius muscle as influenced by the ageing process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006706"}
{"pmid": "21006708", "title": "A comparison of the nutritive value of dextrose and of corn syrups and of the effects produced on their utilization by thiamine.", "content": "A comparison of the nutritive value of dextrose and of corn syrups and of the effects produced on their utilization by thiamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006708"}
{"pmid": "21006709", "title": "Note on the effect of caffeine on ammonia and urea excretion in rabbits.", "content": "Note on the effect of caffeine on ammonia and urea excretion in rabbits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006709"}
{"pmid": "21006711", "title": "The behavioral sequelae of neurosurgical therapy (bilateral prefrontal lobotomy).", "content": "The behavioral sequelae of neurosurgical therapy (bilateral prefrontal lobotomy).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006711"}
{"pmid": "21006710", "title": "The effect of various steroid hormones on the alkaline and acid phosphatases of the kidney of the mouse.", "content": "The effect of various steroid hormones on the alkaline and acid phosphatases of the kidney of the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006710"}
{"pmid": "21006712", "title": "An investigation of the nature of non-directive psychotherapy.", "content": "An investigation of the nature of non-directive psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006712"}
{"pmid": "21006713", "title": "Studies in discrimination learning by monkeys; discriminations between stimuli differing in both color and form, and only in color, and only in form.", "content": "Studies in discrimination learning by monkeys; discriminations between stimuli differing in both color and form, and only in color, and only in form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006713"}
{"pmid": "21006714", "title": "The emotional element in music.", "content": "The emotional element in music.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006714"}
{"pmid": "21006715", "title": "The meaning-frequency relationship of words.", "content": "The meaning-frequency relationship of words.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006715"}
{"pmid": "21006716", "title": "A study of types of word-association in dementia praecox and manic-depressives.", "content": "A study of types of word-association in dementia praecox and manic-depressives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006716"}
{"pmid": "21006717", "title": "A twenty-five year review of the work of the Committee on Administrative Practice.", "content": "A twenty-five year review of the work of the Committee on Administrative Practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006717"}
{"pmid": "21006718", "title": "Recent trenas in the early diagnosis of tuberculosis.", "content": "Recent trenas in the early diagnosis of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006718"}
{"pmid": "21006719", "title": "Prevalence of rheumatic heart disease in Denver school children.", "content": "Prevalence of rheumatic heart disease in Denver school children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006719"}
{"pmid": "21006720", "title": "A public health role for the laundry.", "content": "A public health role for the laundry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006720"}
{"pmid": "21006721", "title": "Distribution of Shigella in India as determined by spot agglutination with absorbed sera.", "content": "Distribution of Shigella in India as determined by spot agglutination with absorbed sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006721"}
{"pmid": "21006722", "title": "Background of current trends in the relation of public health to medical care.", "content": "Background of current trends in the relation of public health to medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006722"}
{"pmid": "21006723", "title": "A method for control of sanitation in food processing plants.", "content": "A method for control of sanitation in food processing plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006723"}
{"pmid": "21006724", "title": "Problems of health education in Latin-America.", "content": "Problems of health education in Latin-America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006724"}
{"pmid": "21006725", "title": "Treatment of pediculosis capitis.", "content": "Treatment of pediculosis capitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006725"}
{"pmid": "21006726", "title": "Public health degrees and certificates granted in the United States and Canada, during the academic year.", "content": "Public health degrees and certificates granted in the United States and Canada, during the academic year.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006726"}
{"pmid": "21006728", "title": "Tonsillectomy in the school medical service; indications.", "content": "Tonsillectomy in the school medical service; indications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006728"}
{"pmid": "21006730", "title": "ERADICATION of bed-bugs; a further note.", "content": "ERADICATION of bed-bugs; a further note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006730"}
{"pmid": "21006729", "title": "The control of cockroaches.", "content": "The control of cockroaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006729"}
{"pmid": "21006732", "title": "Trading the source of infection in cases of tuberculous meningitis of bovine origin.", "content": "Trading the source of infection in cases of tuberculous meningitis of bovine origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006732"}
{"pmid": "21006731", "title": "Studies on the isolation of Bact. typhosum and Bact. paratyphosum B.", "content": "Studies on the isolation of Bact. typhosum and Bact. paratyphosum B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006731"}
{"pmid": "21006733", "title": "Operation of activated sludge plants.", "content": "Operation of activated sludge plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006733"}
{"pmid": "21006734", "title": "Water treatment to reduce chemical odors; experience with various methods at Nitro, W. Va.", "content": "Water treatment to reduce chemical odors; experience with various methods at Nitro, W. Va.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006734"}
{"pmid": "21006736", "title": "The principles of encephalography.", "content": "The principles of encephalography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006736"}
{"pmid": "21006735", "title": "Training; a new conception; the nucleus of a suggested scheme for the training of radiographers from school-leaving age, with remuneration, compared with the present scheme.", "content": "Training; a new conception; the nucleus of a suggested scheme for the training of radiographers from school-leaving age, with remuneration, compared with the present scheme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006735"}
{"pmid": "21006737", "title": "Modified angle block.", "content": "Modified angle block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006737"}
{"pmid": "21006738", "title": "History of military radiographic training.", "content": "History of military radiographic training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006738"}
{"pmid": "21006739", "title": "Surgical treatment of long-standing deep phlebitis of the leg; a supplementary report.", "content": "Surgical treatment of long-standing deep phlebitis of the leg; a supplementary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006739"}
{"pmid": "21006741", "title": "Surgical correction for coarctation of the aorta.", "content": "Surgical correction for coarctation of the aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006741"}
{"pmid": "21006740", "title": "Venous pressures in disorders of the venous system of the lower extremities.", "content": "Venous pressures in disorders of the venous system of the lower extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006740"}
{"pmid": "21006742", "title": "Arteriovenous fistula; a suture technique for producing a lateral anastomosis, an experimental study.", "content": "Arteriovenous fistula; a suture technique for producing a lateral anastomosis, an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006742"}
{"pmid": "21006743", "title": "Successful removal of foreign bodies within the pericardium; a report of two cases.", "content": "Successful removal of foreign bodies within the pericardium; a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006743"}
{"pmid": "21006744", "title": "A routine for early skin grafting of deep burns.", "content": "A routine for early skin grafting of deep burns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006744"}
{"pmid": "21006745", "title": "The intrahilar and related segmental anatomy of the lung.", "content": "The intrahilar and related segmental anatomy of the lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006745"}
{"pmid": "21006747", "title": "Resuscitation of severely wounded casualties.", "content": "Resuscitation of severely wounded casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006747"}
{"pmid": "21006746", "title": "A new design for raising a tubed pedicled flap.", "content": "A new design for raising a tubed pedicled flap.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006746"}
{"pmid": "21006748", "title": "The peritoneal absorption of penicillin.", "content": "The peritoneal absorption of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006748"}
{"pmid": "21006749", "title": "The molded bone graft.", "content": "The molded bone graft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006749"}
{"pmid": "21006750", "title": "Nylon bone suture.", "content": "Nylon bone suture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006750"}
{"pmid": "21006751", "title": "Herniation of nucleus pulposus; refinement in operative technique.", "content": "Herniation of nucleus pulposus; refinement in operative technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006751"}
{"pmid": "21006752", "title": "Chylangioma cavernosum mesenterii; report of a case and review of the literature.", "content": "Chylangioma cavernosum mesenterii; report of a case and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006752"}
{"pmid": "21006753", "title": "A method of retaining an intravenous needle in situ.", "content": "A method of retaining an intravenous needle in situ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006753"}
{"pmid": "21006754", "title": "Traumatic aneurysm; the Matas operation 57 years after.", "content": "Traumatic aneurysm; the Matas operation 57 years after.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006754"}
{"pmid": "21006755", "title": "War injuries of the chest.", "content": "War injuries of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006755"}
{"pmid": "21006756", "title": "Intravenous gelatin for nutritional purposes.", "content": "Intravenous gelatin for nutritional purposes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006756"}
{"pmid": "21006757", "title": "Indications for roentgen therapy of bladder carcinomas.", "content": "Indications for roentgen therapy of bladder carcinomas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006757"}
{"pmid": "21006758", "title": "Reflex sympathetic dystrophy.", "content": "Reflex sympathetic dystrophy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006758"}
{"pmid": "21006759", "title": "A single-stage operative method of management of chronically infected, ununited fractures.", "content": "A single-stage operative method of management of chronically infected, ununited fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006759"}
{"pmid": "21006760", "title": "The saphenous venous tributaries and related structures in relation to the technique of high ligation; based chiefly upon a study of 550 anatomical dissections.", "content": "The saphenous venous tributaries and related structures in relation to the technique of high ligation; based chiefly upon a study of 550 anatomical dissections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006760"}
{"pmid": "21006761", "title": "Thoracoabdominal wounds; a review of 270 cases.", "content": "Thoracoabdominal wounds; a review of 270 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006761"}
{"pmid": "21006762", "title": "Decortication in acute empyema thoracis.", "content": "Decortication in acute empyema thoracis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006762"}
{"pmid": "21006763", "title": "Osteogenic sarcoma; roentgenographic interpretation of growth patterns in bone sarcoma.", "content": "Osteogenic sarcoma; roentgenographic interpretation of growth patterns in bone sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006763"}
{"pmid": "21006764", "title": "Acquired esophagotracheobronchial fistula.", "content": "Acquired esophagotracheobronchial fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006764"}
{"pmid": "21006765", "title": "Gunshot fractures of the femoral shaft.", "content": "Gunshot fractures of the femoral shaft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006765"}
{"pmid": "21006766", "title": "The diagnosis of acute flexor tendon tenosynovitis.", "content": "The diagnosis of acute flexor tendon tenosynovitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006766"}
{"pmid": "21006767", "title": "Strictures of the common duct.", "content": "Strictures of the common duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006767"}
{"pmid": "21006768", "title": "Intravenous amino acids, protein digests; accuracy of terminology.", "content": "Intravenous amino acids, protein digests; accuracy of terminology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006768"}
{"pmid": "21006769", "title": "New technique of simultaneous bilateral uretero-intestinal anastomosis; report of experimental study.", "content": "New technique of simultaneous bilateral uretero-intestinal anastomosis; report of experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006769"}
{"pmid": "21006770", "title": "Lumbar ureterolithotomy; the Foley operation.", "content": "Lumbar ureterolithotomy; the Foley operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006770"}
{"pmid": "21006771", "title": "Congenital valve in the upper ureter.", "content": "Congenital valve in the upper ureter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006771"}
{"pmid": "21006772", "title": "Unilateral triplication of the ureter and renal pelvis.", "content": "Unilateral triplication of the ureter and renal pelvis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006772"}
{"pmid": "21006773", "title": "The use of thrombin (topical) in the control of bleeding associated with prostatic surgery.", "content": "The use of thrombin (topical) in the control of bleeding associated with prostatic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006773"}
{"pmid": "21006774", "title": "Incarceration of the penis.", "content": "Incarceration of the penis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006774"}
{"pmid": "21006775", "title": "The use of the antidiuretic property of pitressin in excretory pyelography.", "content": "The use of the antidiuretic property of pitressin in excretory pyelography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006775"}
{"pmid": "21006777", "title": "The application of a new plastic cast material in urology.", "content": "The application of a new plastic cast material in urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006777"}
{"pmid": "21006776", "title": "Sulfadiazine anuria with urethral stricture.", "content": "Sulfadiazine anuria with urethral stricture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006776"}
{"pmid": "21006778", "title": "The medical kidney.", "content": "The medical kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006778"}
{"pmid": "21006779", "title": "Penicillin resistant abacterial pyuria.", "content": "Penicillin resistant abacterial pyuria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006779"}
{"pmid": "21006780", "title": "Coexisting lesions in the female reproductive and urinary tracts.", "content": "Coexisting lesions in the female reproductive and urinary tracts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006780"}
{"pmid": "21006781", "title": "Urine retention and arterial hypertension.", "content": "Urine retention and arterial hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006781"}
{"pmid": "21006782", "title": "Perineal adenomectomy of the prostate.", "content": "Perineal adenomectomy of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006782"}
{"pmid": "21006783", "title": "The central control of micturition.", "content": "The central control of micturition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006783"}
{"pmid": "21006785", "title": "Keratoderma dissemination hereditarium palmare et plantare; report of a case.", "content": "Keratoderma dissemination hereditarium palmare et plantare; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006785"}
{"pmid": "21006784", "title": "Prevention of surgical complications of the lower urinary tract.", "content": "Prevention of surgical complications of the lower urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006784"}
{"pmid": "21006786", "title": "Puerperal pelvic thrombosis; with report of a case.", "content": "Puerperal pelvic thrombosis; with report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006786"}
{"pmid": "21006787", "title": "Medieval prostitution.", "content": "Medieval prostitution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006787"}
{"pmid": "21006788", "title": "Thrombosis and thrombophlebitis of the renal veins.", "content": "Thrombosis and thrombophlebitis of the renal veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006788"}
{"pmid": "21006789", "title": "End results in the treatment of bladder tumors.", "content": "End results in the treatment of bladder tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006789"}
{"pmid": "21006790", "title": "Has the prostate gland an internal secretion?", "content": "Has the prostate gland an internal secretion?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006790"}
{"pmid": "21006791", "title": "Neurologic manifestations during arsenotherapy for syphilis.", "content": "Neurologic manifestations during arsenotherapy for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006791"}
{"pmid": "21006792", "title": "Allergic neurodermatitis.", "content": "Allergic neurodermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006792"}
{"pmid": "21006793", "title": "Highlights of the Conference in tropical dermatology for American doctors.", "content": "Highlights of the Conference in tropical dermatology for American doctors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006793"}
{"pmid": "21006794", "title": "The nail and its diseases.", "content": "The nail and its diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006794"}
{"pmid": "21006803", "title": "Checklist of the internal and external animal parasites of domestic animals in North America (United States and possessions and Canada).", "content": "Checklist of the internal and external animal parasites of domestic animals in North America (United States and possessions and Canada).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006803"}
{"pmid": "21006804", "title": "Studies on swine enteritis; Salmonella and other enteric organisms isolated from diseased and normal swine.", "content": "Studies on swine enteritis; Salmonella and other enteric organisms isolated from diseased and normal swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006804"}
{"pmid": "21006805", "title": "An active agent isolated from hogs affected with arthritis; preliminary report.", "content": "An active agent isolated from hogs affected with arthritis; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006805"}
{"pmid": "21006806", "title": "The colostrum pregnancy test in cattle.", "content": "The colostrum pregnancy test in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006806"}
{"pmid": "21006807", "title": "The effect of low outdoor temperatures on the free-living stages of some common nematode parasites of sheep.", "content": "The effect of low outdoor temperatures on the free-living stages of some common nematode parasites of sheep.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006807"}
{"pmid": "21006808", "title": "Salmonella types isolated from snakes.", "content": "Salmonella types isolated from snakes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006808"}
{"pmid": "21006809", "title": "Some preliminary observations on the effect of molybdenum on copper metabolism in herbivorous animals.", "content": "Some preliminary observations on the effect of molybdenum on copper metabolism in herbivorous animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006809"}
{"pmid": "21006810", "title": "An acute case of parturient haemoglobinaemia.", "content": "An acute case of parturient haemoglobinaemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006810"}
{"pmid": "21006811", "title": "Children's infections and their control in the USSR in the years of the Great Patriotic War.", "content": "Children's infections and their control in the USSR in the years of the Great Patriotic War.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006811"}
{"pmid": "21006812", "title": "The problem of whooping cough; the present stage and further research.", "content": "The problem of whooping cough; the present stage and further research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006812"}
{"pmid": "21006814", "title": "Pathomorphology of pulmonary deformations in whooping cough.", "content": "Pathomorphology of pulmonary deformations in whooping cough.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006814"}
{"pmid": "21006813", "title": "On the clinics and pathogenesis of whooping cough pneumonias.", "content": "On the clinics and pathogenesis of whooping cough pneumonias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006813"}
{"pmid": "21006816", "title": "Contribution to the etiology of scarlet fever.", "content": "Contribution to the etiology of scarlet fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006816"}
{"pmid": "21006815", "title": "Some data on epidemiology of diphtheria and scarlet fever in the years of the Patriotic War.", "content": "Some data on epidemiology of diphtheria and scarlet fever in the years of the Patriotic War.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006815"}
{"pmid": "21006817", "title": "The significance of hemolytic streptococcus in contagiousness of scarlet fever and continuance of the infectious period in the scarlatinous reconvalescent.", "content": "The significance of hemolytic streptococcus in contagiousness of scarlet fever and continuance of the infectious period in the scarlatinous reconvalescent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006817"}
{"pmid": "21006818", "title": "Experimental measles in monkeys.", "content": "Experimental measles in monkeys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006818"}
{"pmid": "21006820", "title": "On the etiology and pathogenesis of toxic diphtheria.", "content": "On the etiology and pathogenesis of toxic diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006820"}
{"pmid": "21006819", "title": "Characteristics of the hemolytic streptococci excreted by the measles patient showing purulent complications.", "content": "Characteristics of the hemolytic streptococci excreted by the measles patient showing purulent complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006819"}
{"pmid": "21006821", "title": "On the etiology and pathogenesis of toxic diphtheria.", "content": "On the etiology and pathogenesis of toxic diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006821"}
{"pmid": "21006822", "title": "Contribution to the epidemiology of diphtheria.", "content": "Contribution to the epidemiology of diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006822"}
{"pmid": "21006823", "title": "Efficiency of annual immunization against diphtheria.", "content": "Efficiency of annual immunization against diphtheria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006823"}
{"pmid": "21006824", "title": "On the immune state of the organism in various methods of antidiphtheritic vaccination.", "content": "On the immune state of the organism in various methods of antidiphtheritic vaccination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006824"}
{"pmid": "21006825", "title": "Characteristics of diphtheria bacilli-carrying at Krasnoyarsk during 1943.", "content": "Characteristics of diphtheria bacilli-carrying at Krasnoyarsk during 1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006825"}
{"pmid": "21006826", "title": "Laboratory study of diphtheria extrafaucialis.", "content": "Laboratory study of diphtheria extrafaucialis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006826"}
{"pmid": "21006827", "title": "Media for typing of diphtheria bacilli.", "content": "Media for typing of diphtheria bacilli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006827"}
{"pmid": "21006829", "title": "New data on rabies.", "content": "New data on rabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006829"}
{"pmid": "21006830", "title": "Some data on bacteriological characteristics of pneumonia in dystrophics.", "content": "Some data on bacteriological characteristics of pneumonia in dystrophics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006830"}
{"pmid": "21006828", "title": "Sulphidin in the prophylaxis of epidemic cerebrospinal meningitis.", "content": "Sulphidin in the prophylaxis of epidemic cerebrospinal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006828"}
{"pmid": "21006831", "title": "Garro's elective medium?", "content": "Garro's elective medium?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006831"}
{"pmid": "21006832", "title": "The architecture of the cerebral capillary bed.", "content": "The architecture of the cerebral capillary bed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006832"}
{"pmid": "21006833", "title": "The effect of neurohypophysial extracts on the water balance of lower vertebrates.", "content": "The effect of neurohypophysial extracts on the water balance of lower vertebrates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006833"}
{"pmid": "21006834", "title": "Biological methylation.", "content": "Biological methylation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006834"}
{"pmid": "21006835", "title": "On the use of matrices in certain population mathematics.", "content": "On the use of matrices in certain population mathematics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006835"}
{"pmid": "21006836", "title": "Errors in the routine daily measurement of the puerperal uterus.", "content": "Errors in the routine daily measurement of the puerperal uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006836"}
{"pmid": "21006837", "title": "On a method of estimating frequencies.", "content": "On a method of estimating frequencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006837"}
{"pmid": "21006838", "title": "The mathematics of a population composed of kappa stationary strata each recruited from the stratum below and supported at the lowest level by a uniform annual number of entrants.", "content": "The mathematics of a population composed of kappa stationary strata each recruited from the stratum below and supported at the lowest level by a uniform annual number of entrants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006838"}
{"pmid": "21006839", "title": "Moments of gamma and chi 2 for a fourfold table in the absence of association.", "content": "Moments of gamma and chi 2 for a fourfold table in the absence of association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006839"}
{"pmid": "21006840", "title": "The use of chi 2 as a test of homogeniety in a (mu chi 2)-fold table when expectations are small.", "content": "The use of chi 2 as a test of homogeniety in a (mu chi 2)-fold table when expectations are small.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006840"}
{"pmid": "21006841", "title": "The treatment of ties in ranking problems.", "content": "The treatment of ties in ranking problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006841"}
{"pmid": "21006842", "title": "The probability integral of the mean deviation.", "content": "The probability integral of the mean deviation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006842"}
{"pmid": "21006843", "title": "On the distribution of the estimate of mean deviation obtained from samples from a normal population.", "content": "On the distribution of the estimate of mean deviation obtained from samples from a normal population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006843"}
{"pmid": "21006844", "title": "Note on the calculation of the distribution of the estimate of mean deviation in normal samples.", "content": "Note on the calculation of the distribution of the estimate of mean deviation in normal samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006844"}
{"pmid": "21006845", "title": "TABLES of the probability integral of the mean deviation in normal samples.", "content": "TABLES of the probability integral of the mean deviation in normal samples.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006845"}
{"pmid": "21006847", "title": "The flow of a viscous fluid in an elastic tube; a model of the femoral artery.", "content": "The flow of a viscous fluid in an elastic tube; a model of the femoral artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006847"}
{"pmid": "21006846", "title": "Chain processes and their biophysical applications; general theory.", "content": "Chain processes and their biophysical applications; general theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006846"}
{"pmid": "21006848", "title": "A contribution to the mathematical biophysics of cell growth and shapes.", "content": "A contribution to the mathematical biophysics of cell growth and shapes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006848"}
{"pmid": "21006849", "title": "Some remarks on the Boolean algebra of nervous nets in mathematical biophysics.", "content": "Some remarks on the Boolean algebra of nervous nets in mathematical biophysics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006849"}
{"pmid": "21006850", "title": "Some quantitative aspects of shock therapy in psychoses.", "content": "Some quantitative aspects of shock therapy in psychoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006850"}
{"pmid": "21006851", "title": "A note on the mathematical biophysics of central excitation and inhibition.", "content": "A note on the mathematical biophysics of central excitation and inhibition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006851"}
{"pmid": "21006852", "title": "A suggestion for another statistical interpretation of the fundamental equations of the mathematical biophysics of the central nervous system.", "content": "A suggestion for another statistical interpretation of the fundamental equations of the mathematical biophysics of the central nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006852"}
{"pmid": "21006853", "title": "The heterarchy of values determined by the topology of nervous nets.", "content": "The heterarchy of values determined by the topology of nervous nets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006853"}
{"pmid": "21006919", "title": "The nature of fibrositis; the myalgic lesion and its secondary effects; a reflex theory.", "content": "The nature of fibrositis; the myalgic lesion and its secondary effects; a reflex theory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006919"}
{"pmid": "21006920", "title": "A study of rheumatism in a group of soldiers with reference to the incidence of trigger points and fibrositic nodules.", "content": "A study of rheumatism in a group of soldiers with reference to the incidence of trigger points and fibrositic nodules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006920"}
{"pmid": "21006921", "title": "Observations on the treatment of rheumatic fever with vitamin P.", "content": "Observations on the treatment of rheumatic fever with vitamin P.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006921"}
{"pmid": "21006922", "title": "A benign type of rheumatic fever.", "content": "A benign type of rheumatic fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006922"}
{"pmid": "21006923", "title": "Rheumatism in Sweden.", "content": "Rheumatism in Sweden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006923"}
{"pmid": "21006924", "title": "CHRONIC rheumatism in Scotland.", "content": "CHRONIC rheumatism in Scotland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006924"}
{"pmid": "21006925", "title": "Isolation of the acid-soluble nucleotides of liver.", "content": "Isolation of the acid-soluble nucleotides of liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006925"}
{"pmid": "21006926", "title": "The distribution of acid-soluble nucleotides in the livers of rats, fed and fasting.", "content": "The distribution of acid-soluble nucleotides in the livers of rats, fed and fasting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006926"}
{"pmid": "21006927", "title": "On the activation of fatty acid oxidation.", "content": "On the activation of fatty acid oxidation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006927"}
{"pmid": "21006928", "title": "Effect of nicotinic acid amide and sodium on glycolysis and oxygen uptake in brain homogenates.", "content": "Effect of nicotinic acid amide and sodium on glycolysis and oxygen uptake in brain homogenates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006928"}
{"pmid": "21006929", "title": "The influence of age and diet on the lipid composition of the rat.", "content": "The influence of age and diet on the lipid composition of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006929"}
{"pmid": "21006930", "title": "The effect of growth on the lipid composition of rat tissues.", "content": "The effect of growth on the lipid composition of rat tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006930"}
{"pmid": "21006931", "title": "Preparation, properties, and parenteral administration of tryptophane-containing acid hydrolysates of proteins.", "content": "Preparation, properties, and parenteral administration of tryptophane-containing acid hydrolysates of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006931"}
{"pmid": "21006932", "title": "A colorimetric determination of blood acetoin.", "content": "A colorimetric determination of blood acetoin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006932"}
{"pmid": "21006933", "title": "The metabolism of acetaldehyde.", "content": "The metabolism of acetaldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006933"}
{"pmid": "21006934", "title": "The biological activity of pantolactone and pantoic acid.", "content": "The biological activity of pantolactone and pantoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006934"}
{"pmid": "21006935", "title": "Determination of the degree of hydrolysis of partial acid hydrolysates of casein and fibrin.", "content": "Determination of the degree of hydrolysis of partial acid hydrolysates of casein and fibrin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006935"}
{"pmid": "21006936", "title": "The isolation of alpha-glycerylphosphorylcholine from incubated beef pancreas; its significance for the intermediary metabolism of lecithin.", "content": "The isolation of alpha-glycerylphosphorylcholine from incubated beef pancreas; its significance for the intermediary metabolism of lecithin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006936"}
{"pmid": "21006937", "title": "The structural specificity of sulfanilamide-like compounds as inhibitors of the invitro conversion of inorganic iodide to thyroxine and diiodotyrosine by thyroid tissue.", "content": "The structural specificity of sulfanilamide-like compounds as inhibitors of the invitro conversion of inorganic iodide to thyroxine and diiodotyrosine by thyroid tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006937"}
{"pmid": "21006938", "title": "The regeneration of liver protein in the rat.", "content": "The regeneration of liver protein in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006938"}
{"pmid": "21006939", "title": "Transaminases.", "content": "Transaminases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006939"}
{"pmid": "21006940", "title": "Isolation of l-amino acid oxidase.", "content": "Isolation of l-amino acid oxidase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006940"}
{"pmid": "21006941", "title": "Examination of l-amino acid oxidase by electrophoresis and the ultracentrifuge.", "content": "Examination of l-amino acid oxidase by electrophoresis and the ultracentrifuge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006941"}
{"pmid": "21006942", "title": "The quantitative determination of thryoxine in iodinated casein having thyroidal activity.", "content": "The quantitative determination of thryoxine in iodinated casein having thyroidal activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006942"}
{"pmid": "21006943", "title": "The effect of manganese compounds and certain other factors on the formation of thyroxine in iodinated casein.", "content": "The effect of manganese compounds and certain other factors on the formation of thyroxine in iodinated casein.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006943"}
{"pmid": "21006944", "title": "A direct method for determination of oxygen and carbon dioxide tensions in blood.", "content": "A direct method for determination of oxygen and carbon dioxide tensions in blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006944"}
{"pmid": "21006947", "title": "Investigations of amino acids, peptides, and proteins; the amino acid requirements of Lactobacillus fermenti 36.", "content": "Investigations of amino acids, peptides, and proteins; the amino acid requirements of Lactobacillus fermenti 36.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006947"}
{"pmid": "21006945", "title": "The proteolytic inhibiting substance in the extract from unheated soy bean meal and its effect upon growth in chicks.", "content": "The proteolytic inhibiting substance in the extract from unheated soy bean meal and its effect upon growth in chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006945"}
{"pmid": "21006946", "title": "Investigations of amino acids, peptides, and proteins; the determination of phenylalanine in protein hydrolysates with Leuconostoc mesenteroides P-60 and Lactobacillus casei.", "content": "Investigations of amino acids, peptides, and proteins; the determination of phenylalanine in protein hydrolysates with Leuconostoc mesenteroides P-60 and Lactobacillus casei.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006946"}
{"pmid": "21006949", "title": "The determination of creatine and creatinine.", "content": "The determination of creatine and creatinine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006949"}
{"pmid": "21006948", "title": "Investigations of amino acids, peptides, and proteins; the determination of histidine in protein hydrolysates with Lactobacillus fermenti 36.", "content": "Investigations of amino acids, peptides, and proteins; the determination of histidine in protein hydrolysates with Lactobacillus fermenti 36.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006948"}
{"pmid": "21006950", "title": "The determination of catechol, phenol, and hydroquinone in urine.", "content": "The determination of catechol, phenol, and hydroquinone in urine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006950"}
{"pmid": "21006951", "title": "Constituents of the blood of the hibernating and normal rattlesnake, Crotalus horridus.", "content": "Constituents of the blood of the hibernating and normal rattlesnake, Crotalus horridus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006951"}
{"pmid": "21006952", "title": "The effect of phosphate on the solubility of calcium carbonate and of bicarbonate on the solubility of calcium and magnesium phosphates.", "content": "The effect of phosphate on the solubility of calcium carbonate and of bicarbonate on the solubility of calcium and magnesium phosphates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006952"}
{"pmid": "21006953", "title": "The microbiological determination of amino acids in animal proteins.", "content": "The microbiological determination of amino acids in animal proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006953"}
{"pmid": "21006954", "title": "Microbiological determination of free leucine, isoleucine, valine, and threonine in dog plasma.", "content": "Microbiological determination of free leucine, isoleucine, valine, and threonine in dog plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006954"}
{"pmid": "21006955", "title": "Fate of ingested sulfide sulfur labeled with radioactive sulfur in the rat.", "content": "Fate of ingested sulfide sulfur labeled with radioactive sulfur in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006955"}
{"pmid": "21006956", "title": "On the electrophoretic pattern of red blood cell proteins.", "content": "On the electrophoretic pattern of red blood cell proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006956"}
{"pmid": "21006957", "title": "Itatartaric acid, a metabolic product of an ultravioletinduced mutant of Aspergillus terreus.", "content": "Itatartaric acid, a metabolic product of an ultravioletinduced mutant of Aspergillus terreus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006957"}
{"pmid": "21006958", "title": "Some properties of synthetic codecarboxylase.", "content": "Some properties of synthetic codecarboxylase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006958"}
{"pmid": "21006959", "title": "Intermediates of acetate oxidation in kidney.", "content": "Intermediates of acetate oxidation in kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006959"}
{"pmid": "21006960", "title": "A nutritionally produced cerebellar disorder in chicks, not associated with E avitaminosis.", "content": "A nutritionally produced cerebellar disorder in chicks, not associated with E avitaminosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006960"}
{"pmid": "21006961", "title": "Influence of gelatin and tryptophane on nicotinic acid requirement of chicks.", "content": "Influence of gelatin and tryptophane on nicotinic acid requirement of chicks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006961"}
{"pmid": "21006962", "title": "Modifications in the Acetobacter suboxydane assay for p-aminobenzoic acid.", "content": "Modifications in the Acetobacter suboxydane assay for p-aminobenzoic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006962"}
{"pmid": "21006963", "title": "Monolayers of oxidized and heat-bodied linseed oil.", "content": "Monolayers of oxidized and heat-bodied linseed oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006963"}
{"pmid": "21006964", "title": "The effect of sodium silicates on iron oxide surfaces.", "content": "The effect of sodium silicates on iron oxide surfaces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006964"}
{"pmid": "21006965", "title": "Influence of method of deësterification on the viscosity and acid behavior of pectinic acid solutions.", "content": "Influence of method of deësterification on the viscosity and acid behavior of pectinic acid solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006965"}
{"pmid": "21006966", "title": "Kinetics of deësterification of pectin.", "content": "Kinetics of deësterification of pectin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006966"}
{"pmid": "21006967", "title": "Correlation of viscosities of liquids with temperatures.", "content": "Correlation of viscosities of liquids with temperatures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006967"}
{"pmid": "21006968", "title": "The depolarization of light scattered from polymer solutions.", "content": "The depolarization of light scattered from polymer solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006968"}
{"pmid": "21006969", "title": "The thermal decomposition of ethylene iodide catalyzed by iodide ions.", "content": "The thermal decomposition of ethylene iodide catalyzed by iodide ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006969"}
{"pmid": "21006970", "title": "Radio-frequency dielectric properties of dehydrated carrots; application to moisture determination by electrical methods.", "content": "Radio-frequency dielectric properties of dehydrated carrots; application to moisture determination by electrical methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006970"}
{"pmid": "21006971", "title": "Furfural; assets from a liability.", "content": "Furfural; assets from a liability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006971"}
{"pmid": "21006972", "title": "Analysis of essential oils with the aid of refractive dispersion.", "content": "Analysis of essential oils with the aid of refractive dispersion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006972"}
{"pmid": "21006973", "title": "Microbiological methods of analysis.", "content": "Microbiological methods of analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006973"}
{"pmid": "21006974", "title": "PHENOL disinfectants.", "content": "PHENOL disinfectants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006974"}
{"pmid": "21006975", "title": "The control of pain.", "content": "The control of pain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006975"}
{"pmid": "21006976", "title": "CROTONIC ACID and its esters.", "content": "CROTONIC ACID and its esters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006976"}
{"pmid": "21006984", "title": "The use of cheek wires in the treatment of fractures of the maxilla.", "content": "The use of cheek wires in the treatment of fractures of the maxilla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006984"}
{"pmid": "21006985", "title": "A surgical classification of the malerupted mandibular third molar.", "content": "A surgical classification of the malerupted mandibular third molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006985"}
{"pmid": "21006986", "title": "Eruption of lower second premolar in spite of retained second deciduous molar.", "content": "Eruption of lower second premolar in spite of retained second deciduous molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006986"}
{"pmid": "21006977", "title": "The broken mandibular needle.", "content": "The broken mandibular needle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006977"}
{"pmid": "21006978", "title": "The treatment of Vincent's infection with penicillin.", "content": "The treatment of Vincent's infection with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006978"}
{"pmid": "21006980", "title": "The link between ear, nose and throat surgery and dental conditions.", "content": "The link between ear, nose and throat surgery and dental conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006980"}
{"pmid": "21006987", "title": "Report from a maxillo-facial centre at a Royal Air Force casualty clearing station in England.", "content": "Report from a maxillo-facial centre at a Royal Air Force casualty clearing station in England.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006987"}
{"pmid": "21006989", "title": "Nutrition in dentistry.", "content": "Nutrition in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006989"}
{"pmid": "21006988", "title": "Speech problems and their dental significance.", "content": "Speech problems and their dental significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006988"}
{"pmid": "21006982", "title": "How to get the best out of your materials.", "content": "How to get the best out of your materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006982"}
{"pmid": "21006979", "title": "A microhardness instrument for studying surface hardness.", "content": "A microhardness instrument for studying surface hardness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006979"}
{"pmid": "21006990", "title": "Local anesthesia in dentistry.", "content": "Local anesthesia in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006990"}
{"pmid": "21006981", "title": "Reproducing the natural teeth in acrylic resin.", "content": "Reproducing the natural teeth in acrylic resin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006981"}
{"pmid": "21006983", "title": "The practical application of acrylic material in conservative dentistry.", "content": "The practical application of acrylic material in conservative dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006983"}
{"pmid": "21006992", "title": "ORAL manifestations of systemic disorders.", "content": "ORAL manifestations of systemic disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006992"}
{"pmid": "21006993", "title": "Definite protection of cavities and abutment preparations, with low-fusing metal copings and splints used as temporary restorations.", "content": "Definite protection of cavities and abutment preparations, with low-fusing metal copings and splints used as temporary restorations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006993"}
{"pmid": "21006991", "title": "Vincent's stomatitis; a report based on the personal treatment of 175 cases in Army camps.", "content": "Vincent's stomatitis; a report based on the personal treatment of 175 cases in Army camps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006991"}
{"pmid": "21006998", "title": "Correct jaw relationship for full dentures; Pletcher-Durham technic.", "content": "Correct jaw relationship for full dentures; Pletcher-Durham technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006998"}
{"pmid": "21006997", "title": "Jaw fractures of common occurrence.", "content": "Jaw fractures of common occurrence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006997"}
{"pmid": "21006999", "title": "Hypodermic needles for local anesthesia of the mouth and jaws.", "content": "Hypodermic needles for local anesthesia of the mouth and jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006999"}
{"pmid": "21006996", "title": "Freak impacted lower third molar.", "content": "Freak impacted lower third molar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006996"}
{"pmid": "21006995", "title": "Protection for the teeth through the teen-age growth period.", "content": "Protection for the teeth through the teen-age growth period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006995"}
{"pmid": "21006994", "title": "Construction of an acrylic resin dowel crown to be used as an abutment for a fixed bridge.", "content": "Construction of an acrylic resin dowel crown to be used as an abutment for a fixed bridge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21006994"}
{"pmid": "21007000", "title": "Extraction in orthodontia; a tragic failure in many cases.", "content": "Extraction in orthodontia; a tragic failure in many cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007000"}
{"pmid": "21007001", "title": "Maintenance of natural conditions by intermittent pressure supplied by movable-removable bridgework.", "content": "Maintenance of natural conditions by intermittent pressure supplied by movable-removable bridgework.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007001"}
{"pmid": "21007002", "title": "Physiologic tooth and tissue stimulation made possible with precision attachment bridgework.", "content": "Physiologic tooth and tissue stimulation made possible with precision attachment bridgework.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007002"}
{"pmid": "21007003", "title": "The value of functional movement in precision attachment bridgework.", "content": "The value of functional movement in precision attachment bridgework.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007003"}
{"pmid": "21007004", "title": "The use of acrylic resin jacket crowns as abutments for precision attachment bridgework.", "content": "The use of acrylic resin jacket crowns as abutments for precision attachment bridgework.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007004"}
{"pmid": "21007005", "title": "Tissue tolerance in precision bridgework; mucosa, periosteum and bone involved.", "content": "Tissue tolerance in precision bridgework; mucosa, periosteum and bone involved.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007005"}
{"pmid": "21007006", "title": "Esthetics in precision bridgework made possible through use of acrylic resin.", "content": "Esthetics in precision bridgework made possible through use of acrylic resin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007006"}
{"pmid": "21007007", "title": "Protection of abutment teeth by the use of precision attachments.", "content": "Protection of abutment teeth by the use of precision attachments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007007"}
{"pmid": "21007008", "title": "Acrylic resin removable bridgework, employing precision attachments for retention.", "content": "Acrylic resin removable bridgework, employing precision attachments for retention.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007008"}
{"pmid": "21007009", "title": "Operative and laboratory technics for constructing functional precision bridgework.", "content": "Operative and laboratory technics for constructing functional precision bridgework.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007009"}
{"pmid": "21007010", "title": "An application of the mucostatic principle to the precision attachment partial denture.", "content": "An application of the mucostatic principle to the precision attachment partial denture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007010"}
{"pmid": "21007011", "title": "Adaptability of acrylic resin for ponties and copings.", "content": "Adaptability of acrylic resin for ponties and copings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007011"}
{"pmid": "21007012", "title": "Precision bridges for unusual cases; patients saved from necessity for full dentures.", "content": "Precision bridges for unusual cases; patients saved from necessity for full dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007012"}
{"pmid": "21007013", "title": "Stress breaking; effects of buccolingual attachments on removable partial dentures.", "content": "Stress breaking; effects of buccolingual attachments on removable partial dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007013"}
{"pmid": "21007017", "title": "Acrylique.", "content": "Acrylique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007017"}
{"pmid": "21007016", "title": "The Manitoba Medical Service.", "content": "The Manitoba Medical Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007016"}
{"pmid": "21007015", "title": "Penicillin; its use for the treatment of Vincent's infection.", "content": "Penicillin; its use for the treatment of Vincent's infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007015"}
{"pmid": "21007014", "title": "Operative procedure for gold inlays.", "content": "Operative procedure for gold inlays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007014"}
{"pmid": "21007019", "title": "President's message; when the dental officer returns.", "content": "President's message; when the dental officer returns.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007019"}
{"pmid": "21007018", "title": "Economic considerations in reestablishing a dental practice.", "content": "Economic considerations in reestablishing a dental practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007018"}
{"pmid": "21007021", "title": "Dental manpower of Minnesota in the postwar period.", "content": "Dental manpower of Minnesota in the postwar period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007021"}
{"pmid": "21007025", "title": "Opportunities for dental officers in education and research.", "content": "Opportunities for dental officers in education and research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007025"}
{"pmid": "21007020", "title": "Educational opportunities for the returning veteran.", "content": "Educational opportunities for the returning veteran.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007020"}
{"pmid": "21007023", "title": "CHANGES in drugs, chemicals and devices during the war period.", "content": "CHANGES in drugs, chemicals and devices during the war period.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007023"}
{"pmid": "21007022", "title": "DENTAL materials in wartime.", "content": "DENTAL materials in wartime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007022"}
{"pmid": "21007024", "title": "OPPORTUNITIES in the U.S. Public Health Service, Veterans Administration and Army and Navy Dental Corps.", "content": "OPPORTUNITIES in the U.S. Public Health Service, Veterans Administration and Army and Navy Dental Corps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007024"}
{"pmid": "21007026", "title": "Industrial dentistry as a career.", "content": "Industrial dentistry as a career.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007026"}
{"pmid": "21007029", "title": "Roetgenographic examination of children.", "content": "Roetgenographic examination of children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007029"}
{"pmid": "21007027", "title": "Who should enter dental school?", "content": "Who should enter dental school?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007027"}
{"pmid": "21007028", "title": "Wartime legislation.", "content": "Wartime legislation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007028"}
{"pmid": "21007030", "title": "First permanent molar of the child.", "content": "First permanent molar of the child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007030"}
{"pmid": "21007031", "title": "Preventive orthodontics.", "content": "Preventive orthodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007031"}
{"pmid": "21007032", "title": "Oral diseases in children.", "content": "Oral diseases in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007032"}
{"pmid": "21007033", "title": "Dentistry faces political action.", "content": "Dentistry faces political action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007033"}
{"pmid": "21007034", "title": "Pityriasis rubra pilaris and vitamin A.", "content": "Pityriasis rubra pilaris and vitamin A.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007034"}
{"pmid": "21007035", "title": "Constituents of crude carotene of carrots.", "content": "Constituents of crude carotene of carrots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007035"}
{"pmid": "21007038", "title": "Nutritive value of canned foods; effect of commercial canning and short-time storage on ascorbic acid content of grapefruit juice.", "content": "Nutritive value of canned foods; effect of commercial canning and short-time storage on ascorbic acid content of grapefruit juice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007038"}
{"pmid": "21007036", "title": "Magnesium content of meats.", "content": "Magnesium content of meats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007036"}
{"pmid": "21007037", "title": "Blanching of vegetables for freezing; effect of different types of potable water on nutrients of peas and snap beans.", "content": "Blanching of vegetables for freezing; effect of different types of potable water on nutrients of peas and snap beans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007037"}
{"pmid": "21007045", "title": "A nomogram for the preparation of insulin-protamine zinc insulin mixtures.", "content": "A nomogram for the preparation of insulin-protamine zinc insulin mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007045"}
{"pmid": "21007046", "title": "Metabolic abnormalities in obesity: a statistical survey.", "content": "Metabolic abnormalities in obesity: a statistical survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007046"}
{"pmid": "21007047", "title": "Effect of temperature on the experimental production of ulcers in the intestines of dogs.", "content": "Effect of temperature on the experimental production of ulcers in the intestines of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007047"}
{"pmid": "21007039", "title": "Observations on thiamin content of stored wheat.", "content": "Observations on thiamin content of stored wheat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007039"}
{"pmid": "21007048", "title": "The inhibitory effect of mineral oil on the experimental production of ulcers.", "content": "The inhibitory effect of mineral oil on the experimental production of ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007048"}
{"pmid": "21007050", "title": "Staphylococci in gastroenterology.", "content": "Staphylococci in gastroenterology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007050"}
{"pmid": "21007049", "title": "The importance of paracolon organisms with Salmonella and Shigella antigens.", "content": "The importance of paracolon organisms with Salmonella and Shigella antigens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007049"}
{"pmid": "21007052", "title": "The small intestine; a review of recent literature.", "content": "The small intestine; a review of recent literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007052"}
{"pmid": "21007051", "title": "Infectious hepatitis with special reference to its occurrence in wounded men.", "content": "Infectious hepatitis with special reference to its occurrence in wounded men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007051"}
{"pmid": "21007053", "title": "Chronic ulcerative colitis with infantilism and carcinoma of the colon.", "content": "Chronic ulcerative colitis with infantilism and carcinoma of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007053"}
{"pmid": "21007044", "title": "Influence of chemical characteristics of soil on production of vitamin C in leaves of oats.", "content": "Influence of chemical characteristics of soil on production of vitamin C in leaves of oats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007044"}
{"pmid": "21007040", "title": "Ascorbic acid, carotene, chlorophyll, riboflavin, and water content of summer squashes.", "content": "Ascorbic acid, carotene, chlorophyll, riboflavin, and water content of summer squashes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007040"}
{"pmid": "21007054", "title": "Stoppage of bodily growth in a boy with stenosing enteritis.", "content": "Stoppage of bodily growth in a boy with stenosing enteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007054"}
{"pmid": "21007055", "title": "Observations on anorexia.", "content": "Observations on anorexia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007055"}
{"pmid": "21007042", "title": "Effect of steam and hot-water blanching on ascorbic acid content of snap beans and cauliflower.", "content": "Effect of steam and hot-water blanching on ascorbic acid content of snap beans and cauliflower.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007042"}
{"pmid": "21007041", "title": "Comparative tenderness of representative beef muscles.", "content": "Comparative tenderness of representative beef muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007041"}
{"pmid": "21007043", "title": "Influence of chemical characteristics of soil on production of carotene in leaves of oats.", "content": "Influence of chemical characteristics of soil on production of carotene in leaves of oats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007043"}
{"pmid": "21007056", "title": "Cardio-esophageal relaxation.", "content": "Cardio-esophageal relaxation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007056"}
{"pmid": "21007058", "title": "Experimental studies on the excretion of neutral red by the stomach.", "content": "Experimental studies on the excretion of neutral red by the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007058"}
{"pmid": "21007057", "title": "Gastric acidity in rheumatoid arthritis.", "content": "Gastric acidity in rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007057"}
{"pmid": "21007061", "title": "What is the normal body temperature?", "content": "What is the normal body temperature?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007061"}
{"pmid": "21007059", "title": "So-called fever or brucellosis in nervous persons.", "content": "So-called fever or brucellosis in nervous persons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007059"}
{"pmid": "21007060", "title": "Some historical highlights in the development of clinical thermometry.", "content": "Some historical highlights in the development of clinical thermometry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007060"}
{"pmid": "21007062", "title": "The American Journal of Obstetrics and Gynecology 1920-1945.", "content": "The American Journal of Obstetrics and Gynecology 1920-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007062"}
{"pmid": "21007063", "title": "The pathogenesis of postsalpingectomy endometriosis in laparotomy scars.", "content": "The pathogenesis of postsalpingectomy endometriosis in laparotomy scars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007063"}
{"pmid": "21007064", "title": "Therapeutic aspects of uterotubal insufflation in sterility.", "content": "Therapeutic aspects of uterotubal insufflation in sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007064"}
{"pmid": "21007065", "title": "Sweet gland tumors of the vulva, benign (hidradenoma) and malignant (adenocarcinoma).", "content": "Sweet gland tumors of the vulva, benign (hidradenoma) and malignant (adenocarcinoma).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007065"}
{"pmid": "21007066", "title": "Ten years of cesarean section at the Boston Lying-in Hospital.", "content": "Ten years of cesarean section at the Boston Lying-in Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007066"}
{"pmid": "21007067", "title": "A review of the problem of cancer of the cervix since the use of radium in 1912.", "content": "A review of the problem of cancer of the cervix since the use of radium in 1912.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007067"}
{"pmid": "21007068", "title": "The curability of granulosa-cell tumors.", "content": "The curability of granulosa-cell tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007068"}
{"pmid": "21007069", "title": "Diet regulation and controlled weight in pregnancy.", "content": "Diet regulation and controlled weight in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007069"}
{"pmid": "21007070", "title": "Government and maternal welfare.", "content": "Government and maternal welfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007070"}
{"pmid": "21007072", "title": "The surgical correction of congenital aplasia of the vagina.", "content": "The surgical correction of congenital aplasia of the vagina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007072"}
{"pmid": "21007071", "title": "The Rh factor in obstetrics.", "content": "The Rh factor in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007071"}
{"pmid": "21007073", "title": "Hypertrophy of the uterus.", "content": "Hypertrophy of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007073"}
{"pmid": "21007074", "title": "Aneurysm of the splenic artery with rupture, a rare complication of pregnancy.", "content": "Aneurysm of the splenic artery with rupture, a rare complication of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007074"}
{"pmid": "21007075", "title": "The search for the female sex hormones.", "content": "The search for the female sex hormones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007075"}
{"pmid": "21007078", "title": "Investigation of childlessness.", "content": "Investigation of childlessness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007078"}
{"pmid": "21007076", "title": "The role of Porro cesarean section in modern obstetrics.", "content": "The role of Porro cesarean section in modern obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007076"}
{"pmid": "21007077", "title": "Ectopic gestation; the diagnostic value of cul-de-sac aspiration.", "content": "Ectopic gestation; the diagnostic value of cul-de-sac aspiration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007077"}
{"pmid": "21007079", "title": "Baryta.", "content": "Baryta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007079"}
{"pmid": "21007080", "title": "Short proving of iridium chloride.", "content": "Short proving of iridium chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007080"}
{"pmid": "21007081", "title": "Homoeopathic therapy in some nerve diseases.", "content": "Homoeopathic therapy in some nerve diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007081"}
{"pmid": "21007082", "title": "Homeopathy and surgery.", "content": "Homeopathy and surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007082"}
{"pmid": "21007083", "title": "Catharrhal jaundice; report of a case.", "content": "Catharrhal jaundice; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007083"}
{"pmid": "21007084", "title": "Homeopathic authors.", "content": "Homeopathic authors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007084"}
{"pmid": "21007085", "title": "Sulphur from another angle.", "content": "Sulphur from another angle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007085"}
{"pmid": "21007086", "title": "Basic urology.", "content": "Basic urology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007086"}
{"pmid": "21007087", "title": "The shell-pad-strap method of fitting, and the fabrication of, flexible appliances.", "content": "The shell-pad-strap method of fitting, and the fabrication of, flexible appliances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007087"}
{"pmid": "21007088", "title": "The Polokoff pad.", "content": "The Polokoff pad.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007088"}
{"pmid": "21007089", "title": "Coordination; report on Salem Hospital's growth as a center of area-wide service.", "content": "Coordination; report on Salem Hospital's growth as a center of area-wide service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007089"}
{"pmid": "21007090", "title": "Lengthening shadow of the hospital pharmacist.", "content": "Lengthening shadow of the hospital pharmacist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007090"}
{"pmid": "21007091", "title": "BARBWIRE hospital; how six medical officers fought Germany behind the German line.", "content": "BARBWIRE hospital; how six medical officers fought Germany behind the German line.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007091"}
{"pmid": "21007092", "title": "In the wisely planned utility building, the value is multiplied.", "content": "In the wisely planned utility building, the value is multiplied.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007092"}
{"pmid": "21007096", "title": "The consideration and evaluation of perquisites in determining the wage and salary scale of hospital staff members and personnel.", "content": "The consideration and evaluation of perquisites in determining the wage and salary scale of hospital staff members and personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007096"}
{"pmid": "21007094", "title": "President Truman's message on the National health program.", "content": "President Truman's message on the National health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007094"}
{"pmid": "21007093", "title": "How Arkansas hospitals and health department built a program for care of the indigent.", "content": "How Arkansas hospitals and health department built a program for care of the indigent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007093"}
{"pmid": "21007095", "title": "The National Health Act of 1945.", "content": "The National Health Act of 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007095"}
{"pmid": "21007097", "title": "The Hospital Construction Act (S.191).", "content": "The Hospital Construction Act (S.191).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007097"}
{"pmid": "21007098", "title": "Food-poisoning staphylococci and the order of their resistance to penicillin; inhibition of coagulase production.", "content": "Food-poisoning staphylococci and the order of their resistance to penicillin; inhibition of coagulase production.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007098"}
{"pmid": "21007099", "title": "Production of Clostridium perfringens alpha toxin.", "content": "Production of Clostridium perfringens alpha toxin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007099"}
{"pmid": "21007100", "title": "Anaphylactic properties of photo-oxidized rabbit-antisera (VS sheep erythrocytes and pneumococci) and horse-antiserum (VS diphtherial toxin) containing univalent antibodies.", "content": "Anaphylactic properties of photo-oxidized rabbit-antisera (VS sheep erythrocytes and pneumococci) and horse-antiserum (VS diphtherial toxin) containing univalent antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007100"}
{"pmid": "21007101", "title": "Protective value of univalent antibodies produced by photo-oxidation of antipneumococcal rabbit-serum and antidiphtheric horse-serum.", "content": "Protective value of univalent antibodies produced by photo-oxidation of antipneumococcal rabbit-serum and antidiphtheric horse-serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007101"}
{"pmid": "21007102", "title": "The determination of meningococcic antibodies by a centrifuge-agglutination test.", "content": "The determination of meningococcic antibodies by a centrifuge-agglutination test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007102"}
{"pmid": "21007104", "title": "An electrophoretic study of an anti-influenzal horse serum.", "content": "An electrophoretic study of an anti-influenzal horse serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007104"}
{"pmid": "21007103", "title": "The role of ether anesthesia in the production of influenza virus pneumonia in mice.", "content": "The role of ether anesthesia in the production of influenza virus pneumonia in mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007103"}
{"pmid": "21007105", "title": "Serologic studies in typhus-vaccinated individuals; the effect of a stimulating dose of typhus vaccine on the Weil-Felix and complement-fixing antibodies.", "content": "Serologic studies in typhus-vaccinated individuals; the effect of a stimulating dose of typhus vaccine on the Weil-Felix and complement-fixing antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007105"}
{"pmid": "21007116", "title": "Patients and prejudice; lay attitudes toward women physicians.", "content": "Patients and prejudice; lay attitudes toward women physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007116"}
{"pmid": "21007117", "title": "Antipathy and social behavior.", "content": "Antipathy and social behavior.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007117"}
{"pmid": "21007118", "title": "Studies of the effects of ammonium picrate on man and certain experimental animals.", "content": "Studies of the effects of ammonium picrate on man and certain experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007118"}
{"pmid": "21007119", "title": "Observations on the Fujiwara reaction as a test for chlorinated hydrocarbons.", "content": "Observations on the Fujiwara reaction as a test for chlorinated hydrocarbons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007119"}
{"pmid": "21007120", "title": "Animal studies on the toxicity of inhaled antimony trioxide.", "content": "Animal studies on the toxicity of inhaled antimony trioxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007120"}
{"pmid": "21007122", "title": "Calcium cyanide gas for animal experiments.", "content": "Calcium cyanide gas for animal experiments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007122"}
{"pmid": "21007121", "title": "Observations on the effects of gamma-valero-lactone upon experimental animals.", "content": "Observations on the effects of gamma-valero-lactone upon experimental animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007121"}
{"pmid": "21007123", "title": "POSTWAR outlook for physicians.", "content": "POSTWAR outlook for physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007123"}
{"pmid": "21007129", "title": "[The problem of the biological nature of the viruses].", "content": "[The problem of the biological nature of the viruses].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007129"}
{"pmid": "21007125", "title": "Continuous caudal obstetrical analgesia.", "content": "Continuous caudal obstetrical analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007125"}
{"pmid": "21007126", "title": "Rh hazards in general practice.", "content": "Rh hazards in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007126"}
{"pmid": "21007131", "title": "[On the functional role of the chondriosomic apparatus of a cell].", "content": "[On the functional role of the chondriosomic apparatus of a cell].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007131"}
{"pmid": "21007130", "title": "[Stimulation of the growth of microbes of the intestinal group].", "content": "[Stimulation of the growth of microbes of the intestinal group].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007130"}
{"pmid": "21007124", "title": "Significance of some of the fundamental physical findings in examination of the heart.", "content": "Significance of some of the fundamental physical findings in examination of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007124"}
{"pmid": "21007133", "title": "[Histological observations of the transplanted epichondrion].", "content": "[Histological observations of the transplanted epichondrion].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007133"}
{"pmid": "21007132", "title": "[The effect of various metals on the conjunctive elements of mammalian liver; first communication].", "content": "[The effect of various metals on the conjunctive elements of mammalian liver; first communication].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007132"}
{"pmid": "21007136", "title": "[Subvital congo red testing].", "content": "[Subvital congo red testing].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007136"}
{"pmid": "21007134", "title": "[Ectoplasmatic process of formation of collageneous fibres in the histogenesis of the smooth muscles of the amnion of the chick embryo].", "content": "[Ectoplasmatic process of formation of collageneous fibres in the histogenesis of the smooth muscles of the amnion of the chick embryo].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007134"}
{"pmid": "21007135", "title": "[On the structures formed in the elements of white blood in supravital staining].", "content": "[On the structures formed in the elements of white blood in supravital staining].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007135"}
{"pmid": "21007139", "title": "[Intra vitam washing of the organism with homologous blood associated with full substitution of the recipient's blood by that of a donor].", "content": "[Intra vitam washing of the organism with homologous blood associated with full substitution of the recipient's blood by that of a donor].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007139"}
{"pmid": "21007137", "title": "[Glycogen loading of the interneuron synapsis and its functional sequels; the morphology of glycogen distribution and transmutation].", "content": "[Glycogen loading of the interneuron synapsis and its functional sequels; the morphology of glycogen distribution and transmutation].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007137"}
{"pmid": "21007138", "title": "[Blood changes in traumatic shock of war].", "content": "[Blood changes in traumatic shock of war].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007138"}
{"pmid": "21007140", "title": "[The role of diet in the morphological deformations of the intestinal wall in experimental mechanical ileus in dogs].", "content": "[The role of diet in the morphological deformations of the intestinal wall in experimental mechanical ileus in dogs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007140"}
{"pmid": "21007142", "title": "[Secretory activity of the stomach in dogs during stay on Mt. Elbruz].", "content": "[Secretory activity of the stomach in dogs during stay on Mt. Elbruz].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007142"}
{"pmid": "21007141", "title": "[On the absorptive function of the membrana mucosa of the mouth].", "content": "[On the absorptive function of the membrana mucosa of the mouth].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007141"}
{"pmid": "21007143", "title": "[Evolution of the structure and function of the stomach and pancreas with respect to age].", "content": "[Evolution of the structure and function of the stomach and pancreas with respect to age].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007143"}
{"pmid": "21007145", "title": "[Ions as a receptor irritator].", "content": "[Ions as a receptor irritator].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007145"}
{"pmid": "21007144", "title": "[The influence of ions in formation of vitamins in the yeast cell].", "content": "[The influence of ions in formation of vitamins in the yeast cell].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007144"}
{"pmid": "21007148", "title": "[Electroencephalographic examination in air contusion].", "content": "[Electroencephalographic examination in air contusion].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007148"}
{"pmid": "21007147", "title": "[Electro-encephalography in trauma of the brain].", "content": "[Electro-encephalography in trauma of the brain].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007147"}
{"pmid": "21007149", "title": "[The currents of muscle action in damages of the nerve trunks].", "content": "[The currents of muscle action in damages of the nerve trunks].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007149"}
{"pmid": "21007150", "title": "[The character of electric potentials of the glossopharyngeal nerve in taste irritation of the tongue].", "content": "[The character of electric potentials of the glossopharyngeal nerve in taste irritation of the tongue].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007150"}
{"pmid": "21007151", "title": "[Chronaxometric investigations in gunshot wounds of the median nerve].", "content": "[Chronaxometric investigations in gunshot wounds of the median nerve].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007151"}
{"pmid": "21007146", "title": "[Activity of carbohydrase in disturbances of the acidoalkaline balance in the organism].", "content": "[Activity of carbohydrase in disturbances of the acidoalkaline balance in the organism].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007146"}
{"pmid": "21007152", "title": "[On the dependence of the sexual reflexes of the skeleton muscles on irritation of the glandulae glomiformae].", "content": "[On the dependence of the sexual reflexes of the skeleton muscles on irritation of the glandulae glomiformae].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007152"}
{"pmid": "21007153", "title": "The in-vitro sensitivity of H. influenzae to penicillin, with special reference to meningeal strains of Pittman's Type b.", "content": "The in-vitro sensitivity of H. influenzae to penicillin, with special reference to meningeal strains of Pittman's Type b.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007153"}
{"pmid": "21007157", "title": "Typhoid fever complicated by benign tertian malaria.", "content": "Typhoid fever complicated by benign tertian malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007157"}
{"pmid": "21007155", "title": "Repatriation; a psychiatric study of 100 naval ex-prisoners of war.", "content": "Repatriation; a psychiatric study of 100 naval ex-prisoners of war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007155"}
{"pmid": "21007154", "title": "Meningitis due to a penicillin- and sulphonamide-sensitive Pittman b strain of H. influenzae; recovery.", "content": "Meningitis due to a penicillin- and sulphonamide-sensitive Pittman b strain of H. influenzae; recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007154"}
{"pmid": "21007156", "title": "Sixth-nerve paralysis after spinal analgesia.", "content": "Sixth-nerve paralysis after spinal analgesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007156"}
{"pmid": "21007158", "title": "Neurological complications in cerebrospinal meningitis treated with penicillin.", "content": "Neurological complications in cerebrospinal meningitis treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007158"}
{"pmid": "21007160", "title": "Impressions of surgery in West Africa.", "content": "Impressions of surgery in West Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007160"}
{"pmid": "21007159", "title": "Myxoedema induced by thiouracil.", "content": "Myxoedema induced by thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007159"}
{"pmid": "21007162", "title": "Treatment of varicose ulcers.", "content": "Treatment of varicose ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007162"}
{"pmid": "21007161", "title": "Protein metabolism.", "content": "Protein metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007161"}
{"pmid": "21007163", "title": "Morphine as a prophylactic for ileus.", "content": "Morphine as a prophylactic for ileus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007163"}
{"pmid": "21007165", "title": "Significance of the E.S.R.", "content": "Significance of the E.S.R.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007165"}
{"pmid": "21007164", "title": "Non-specific mesenteric lymphadenitis.", "content": "Non-specific mesenteric lymphadenitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007164"}
{"pmid": "21007166", "title": "PROPOSED national health service; fundamental principles of the medical profession.", "content": "PROPOSED national health service; fundamental principles of the medical profession.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007166"}
{"pmid": "21007167", "title": "Survey of fracture treatment.", "content": "Survey of fracture treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007167"}
{"pmid": "21007168", "title": "Nutrition in Vienna in September, 1945.", "content": "Nutrition in Vienna in September, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007168"}
{"pmid": "21007169", "title": "Toxic effects of 2,2-bis (p-chlorphenyl) l,l,l-trichlorethane (D.D.T.) in man.", "content": "Toxic effects of 2,2-bis (p-chlorphenyl) l,l,l-trichlorethane (D.D.T.) in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007169"}
{"pmid": "21007170", "title": "A fatal case of D.D.T. poisoning in a child, with an account of two accidental deaths in dogs.", "content": "A fatal case of D.D.T. poisoning in a child, with an account of two accidental deaths in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007170"}
{"pmid": "21007171", "title": "Observations on keratoconjunctivitis (cases seen in military hospitals).", "content": "Observations on keratoconjunctivitis (cases seen in military hospitals).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007171"}
{"pmid": "21007172", "title": "A case of tick typhus in the Sudan.", "content": "A case of tick typhus in the Sudan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007172"}
{"pmid": "21007175", "title": "Descent of the testis.", "content": "Descent of the testis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007175"}
{"pmid": "21007173", "title": "Administration of penicillin by intramuscular drip.", "content": "Administration of penicillin by intramuscular drip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007173"}
{"pmid": "21007174", "title": "STETHOSCOPE versus x rays.", "content": "STETHOSCOPE versus x rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007174"}
{"pmid": "21007176", "title": "Non-specific mesenteric lymphadenitis.", "content": "Non-specific mesenteric lymphadenitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007176"}
{"pmid": "21007177", "title": "Volvulus of small intestine.", "content": "Volvulus of small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007177"}
{"pmid": "21007178", "title": "Prostatic obstruction.", "content": "Prostatic obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007178"}
{"pmid": "21007179", "title": "B.L.A. medicine.", "content": "B.L.A. medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007179"}
{"pmid": "21007180", "title": "Estimation of serum proteins by the Linderström-Lang gradient.", "content": "Estimation of serum proteins by the Linderström-Lang gradient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007180"}
{"pmid": "21007181", "title": "Liver function in infective hepatitis gauged by hippuric acid synthesis tests.", "content": "Liver function in infective hepatitis gauged by hippuric acid synthesis tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007181"}
{"pmid": "21007182", "title": "Management of recent fracture-dislocations of the cervical spine.", "content": "Management of recent fracture-dislocations of the cervical spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007182"}
{"pmid": "21007183", "title": "The therapeutic efficiency of ultra-violet-light apparatus; a comparison of tests.", "content": "The therapeutic efficiency of ultra-violet-light apparatus; a comparison of tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007183"}
{"pmid": "21007184", "title": "Anti-M iso-agglutinins in human serum.", "content": "Anti-M iso-agglutinins in human serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007184"}
{"pmid": "21007185", "title": "Treatment of chilblains by paravertebral sympathetic block.", "content": "Treatment of chilblains by paravertebral sympathetic block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007185"}
{"pmid": "21007186", "title": "Duodenal atresia in a newborn infant.", "content": "Duodenal atresia in a newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007186"}
{"pmid": "21007187", "title": "Losses of Polish medicine.", "content": "Losses of Polish medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007187"}
{"pmid": "21007188", "title": "Contributions of the war effort to medicine.", "content": "Contributions of the war effort to medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007188"}
{"pmid": "21007190", "title": "What can the practitioner do in treating the neuroses?", "content": "What can the practitioner do in treating the neuroses?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007190"}
{"pmid": "21007189", "title": "Modern concepts of war neuroses.", "content": "Modern concepts of war neuroses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007189"}
{"pmid": "21007191", "title": "Evaluation of early postoperative activity.", "content": "Evaluation of early postoperative activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007191"}
{"pmid": "21007192", "title": "Psychopathic personality; the use of this term in the Canadian Army overseas.", "content": "Psychopathic personality; the use of this term in the Canadian Army overseas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007192"}
{"pmid": "21007193", "title": "The transplantation of skin.", "content": "The transplantation of skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007193"}
{"pmid": "21007194", "title": "Fungous infections of the skin.", "content": "Fungous infections of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007194"}
{"pmid": "21007195", "title": "Menstruation and its disorders.", "content": "Menstruation and its disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007195"}
{"pmid": "21007196", "title": "CHRYSANTHEMUMS vs. malaria.", "content": "CHRYSANTHEMUMS vs. malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007196"}
{"pmid": "21007197", "title": "Observations on the treatment of infantile paralysis in the acute stage.", "content": "Observations on the treatment of infantile paralysis in the acute stage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007197"}
{"pmid": "21007198", "title": "Bronchoscopy in the treatment of pulmonary atelectasis.", "content": "Bronchoscopy in the treatment of pulmonary atelectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007198"}
{"pmid": "21007200", "title": "Results of a random chest x-ray survey of healthy troops in Canada.", "content": "Results of a random chest x-ray survey of healthy troops in Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007200"}
{"pmid": "21007199", "title": "Visual signs in diagnosis.", "content": "Visual signs in diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007199"}
{"pmid": "21007201", "title": "Forward abdominal surgery; an analysis of 230 cases.", "content": "Forward abdominal surgery; an analysis of 230 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007201"}
{"pmid": "21007202", "title": "Treatment of obesity by appetite-depressing drugs.", "content": "Treatment of obesity by appetite-depressing drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007202"}
{"pmid": "21007203", "title": "A study of causes of blindness in over 12,000 cases in Canada.", "content": "A study of causes of blindness in over 12,000 cases in Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007203"}
{"pmid": "21007204", "title": "Anatomical clinics.", "content": "Anatomical clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007204"}
{"pmid": "21007205", "title": "Benzyl-benzoate and wool dermatitis.", "content": "Benzyl-benzoate and wool dermatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007205"}
{"pmid": "21007207", "title": "Metastatic carcinoma of the choroid.", "content": "Metastatic carcinoma of the choroid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007207"}
{"pmid": "21007208", "title": "A simple method for spinal anesthesia in anorectal surgery.", "content": "A simple method for spinal anesthesia in anorectal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007208"}
{"pmid": "21007209", "title": "An evaluation of roentgen pelvimetry.", "content": "An evaluation of roentgen pelvimetry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007209"}
{"pmid": "21007211", "title": "Religion and medicine.", "content": "Religion and medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007211"}
{"pmid": "21007210", "title": "Phimosis from the flesh fly, Wohlfahrtia vigil.", "content": "Phimosis from the flesh fly, Wohlfahrtia vigil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007210"}
{"pmid": "21007212", "title": "Nasotracheal anaesthesia for tonsillectomy and teeth extraction.", "content": "Nasotracheal anaesthesia for tonsillectomy and teeth extraction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007212"}
{"pmid": "21007213", "title": "Wilhelm Conrad Röntgen (1845-1923) and the early development of radiology.", "content": "Wilhelm Conrad Röntgen (1845-1923) and the early development of radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007213"}
{"pmid": "21007215", "title": "The treatment of weak, painful feet.", "content": "The treatment of weak, painful feet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007215"}
{"pmid": "21007216", "title": "Adrenal disease.", "content": "Adrenal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007216"}
{"pmid": "21007217", "title": "The diagnosis of nephritis.", "content": "The diagnosis of nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007217"}
{"pmid": "21007214", "title": "Clinical and epidemiologic notes on undulant fever (brucellosis).", "content": "Clinical and epidemiologic notes on undulant fever (brucellosis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007214"}
{"pmid": "21007218", "title": "PERITONEOSCOPY.", "content": "PERITONEOSCOPY.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007218"}
{"pmid": "21007219", "title": "Rheumatic fever; etiology, epidemiology, prevalence.", "content": "Rheumatic fever; etiology, epidemiology, prevalence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007219"}
{"pmid": "21007220", "title": "A case of extreme mediastinal dislocation complicating tuberculosis.", "content": "A case of extreme mediastinal dislocation complicating tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007220"}
{"pmid": "21007221", "title": "The deficiency pattern of the small bowel.", "content": "The deficiency pattern of the small bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007221"}
{"pmid": "21007222", "title": "The presence of copper and lead in some human tissues.", "content": "The presence of copper and lead in some human tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007222"}
{"pmid": "21007224", "title": "Cerebral malaria.", "content": "Cerebral malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007224"}
{"pmid": "21007225", "title": "Silico-tuberculosis.", "content": "Silico-tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007225"}
{"pmid": "21007223", "title": "NEUROGENIC bladder.", "content": "NEUROGENIC bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007223"}
{"pmid": "21007233", "title": "Posterior gastroenterostomy for infantile pyloric stenosis.", "content": "Posterior gastroenterostomy for infantile pyloric stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007233"}
{"pmid": "21007234", "title": "Colles fracture; a review of treatment.", "content": "Colles fracture; a review of treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007234"}
{"pmid": "21007235", "title": "Neurofibroma of the bladder; report of a case.", "content": "Neurofibroma of the bladder; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007235"}
{"pmid": "21007226", "title": "Tularemic pneumonia; report of case.", "content": "Tularemic pneumonia; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007226"}
{"pmid": "21007236", "title": "Rupture of a dissecting aortic aneurysm; report of a fatal case.", "content": "Rupture of a dissecting aortic aneurysm; report of a fatal case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007236"}
{"pmid": "21007237", "title": "Human brucellosis.", "content": "Human brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007237"}
{"pmid": "21007238", "title": "Melanocarcinoma of the vagina; a case report.", "content": "Melanocarcinoma of the vagina; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007238"}
{"pmid": "21007239", "title": "Allergic rhinitis.", "content": "Allergic rhinitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007239"}
{"pmid": "21007240", "title": "Fractures of the neck of the femur.", "content": "Fractures of the neck of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007240"}
{"pmid": "21007241", "title": "Plastic procedures about the eyes.", "content": "Plastic procedures about the eyes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007241"}
{"pmid": "21007242", "title": "Indications and contraindications to gastroscopy.", "content": "Indications and contraindications to gastroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007242"}
{"pmid": "21007243", "title": "Orbital proptosis.", "content": "Orbital proptosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007243"}
{"pmid": "21007244", "title": "Emotional control a factor in preserving the integrity of the heart.", "content": "Emotional control a factor in preserving the integrity of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007244"}
{"pmid": "21007245", "title": "The Rorschach test in postencephalitis.", "content": "The Rorschach test in postencephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007245"}
{"pmid": "21007247", "title": "The Illinois Hospital Survey.", "content": "The Illinois Hospital Survey.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007247"}
{"pmid": "21007246", "title": "Hemorrhagic ancephalopathy following five day treatment of early syphilis with massive doses of mapharsen; report of a case with recovery.", "content": "Hemorrhagic ancephalopathy following five day treatment of early syphilis with massive doses of mapharsen; report of a case with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007246"}
{"pmid": "21007248", "title": "Uncommon etiological factors in pathological conditions of the gall-bladder.", "content": "Uncommon etiological factors in pathological conditions of the gall-bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007248"}
{"pmid": "21007251", "title": "The occurrence of leptospirosis in Orissa.", "content": "The occurrence of leptospirosis in Orissa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007251"}
{"pmid": "21007249", "title": "Occurrence of fluorosis in endemic forms in Hyderabad state.", "content": "Occurrence of fluorosis in endemic forms in Hyderabad state.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007249"}
{"pmid": "21007250", "title": "Leptospirosis without jaundice.", "content": "Leptospirosis without jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007250"}
{"pmid": "21007252", "title": "The unsuitability of white mice for studies of leptospirosis.", "content": "The unsuitability of white mice for studies of leptospirosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007252"}
{"pmid": "21007253", "title": "Sulphapyridine in gonorrhoea.", "content": "Sulphapyridine in gonorrhoea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007253"}
{"pmid": "21007255", "title": "An easy method of producing permanent rough variation in cholera vibrios.", "content": "An easy method of producing permanent rough variation in cholera vibrios.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007255"}
{"pmid": "21007254", "title": "Bronchial asthma and pulmonary tuberculosis.", "content": "Bronchial asthma and pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007254"}
{"pmid": "21007256", "title": "Turmeric and vegetable oils as repellents against anopheline mosquitoes.", "content": "Turmeric and vegetable oils as repellents against anopheline mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007256"}
{"pmid": "21007257", "title": "Tropical ulcer; a study of one hundred cases collected in the city of Madras.", "content": "Tropical ulcer; a study of one hundred cases collected in the city of Madras.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007257"}
{"pmid": "21007258", "title": "Application of the D.E.C. medium to the isolation of typhoid bacilli from sewage in Calcutta.", "content": "Application of the D.E.C. medium to the isolation of typhoid bacilli from sewage in Calcutta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007258"}
{"pmid": "21007259", "title": "Rapid method of paraffin embedding.", "content": "Rapid method of paraffin embedding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007259"}
{"pmid": "21007261", "title": "Myotonia congenita (Thomsen's disease).", "content": "Myotonia congenita (Thomsen's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007261"}
{"pmid": "21007262", "title": "Congenital heart disease in a case of resistant kala-azar with pulmonary tuberculosis.", "content": "Congenital heart disease in a case of resistant kala-azar with pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007262"}
{"pmid": "21007260", "title": "Blood-pressure variation and cardiovascular changes in diabetes mellitus.", "content": "Blood-pressure variation and cardiovascular changes in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007260"}
{"pmid": "21007264", "title": "Hepatic amoebiasis.", "content": "Hepatic amoebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007264"}
{"pmid": "21007263", "title": "The use of the femoral vein for venoclysis.", "content": "The use of the femoral vein for venoclysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007263"}
{"pmid": "21007265", "title": "Does sulphapyridine really delay resolution in pneumonia.", "content": "Does sulphapyridine really delay resolution in pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007265"}
{"pmid": "21007266", "title": "Clinical observations on penicillin.", "content": "Clinical observations on penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007266"}
{"pmid": "21007267", "title": "Minimal lesion in pulmonary tuberculosis; how to make it out and to treat it to prevent its break-down.", "content": "Minimal lesion in pulmonary tuberculosis; how to make it out and to treat it to prevent its break-down.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007267"}
{"pmid": "21007268", "title": "DIAGNOSIS of kala-azar febrile and afebrile cases.", "content": "DIAGNOSIS of kala-azar febrile and afebrile cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007268"}
{"pmid": "21007269", "title": "The liver.", "content": "The liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007269"}
{"pmid": "21007271", "title": "The responsibility of the private physician in tuberculosis control.", "content": "The responsibility of the private physician in tuberculosis control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007271"}
{"pmid": "21007272", "title": "The etiology of Colorado tick fever.", "content": "The etiology of Colorado tick fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007272"}
{"pmid": "21007270", "title": "Tachycardia and its treatment.", "content": "Tachycardia and its treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007270"}
{"pmid": "21007273", "title": "The preparation of highly purified PRS influenza virus from infected mouse lungs.", "content": "The preparation of highly purified PRS influenza virus from infected mouse lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007273"}
{"pmid": "21007277", "title": "Dicumarol therapy in acute coronary thombosis; results in fifty attacks; with review of data on embolic complications and immediate mortality in myocardial infarction.", "content": "Dicumarol therapy in acute coronary thombosis; results in fifty attacks; with review of data on embolic complications and immediate mortality in myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007277"}
{"pmid": "21007274", "title": "Studies on pneumonia virus of mice (PVM); the precision of measurements in vivo of the virus and antibodies against it.", "content": "Studies on pneumonia virus of mice (PVM); the precision of measurements in vivo of the virus and antibodies against it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007274"}
{"pmid": "21007275", "title": "Studies on pneumonia virus of mice (PVM); immunological evidence of latent infection with the virus in numerous mammalian species.", "content": "Studies on pneumonia virus of mice (PVM); immunological evidence of latent infection with the virus in numerous mammalian species.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007275"}
{"pmid": "21007276", "title": "Studies on the nature of resistance of gram-negative bacilli to penicillin; antagonistic and enhancing effects of amino acids.", "content": "Studies on the nature of resistance of gram-negative bacilli to penicillin; antagonistic and enhancing effects of amino acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007276"}
{"pmid": "21007278", "title": "Rehabilitation of the warworn civilian.", "content": "Rehabilitation of the warworn civilian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007278"}
{"pmid": "21007279", "title": "Loeffler's syndrome.", "content": "Loeffler's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007279"}
{"pmid": "21007280", "title": "The medical profession today and tomorrow.", "content": "The medical profession today and tomorrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007280"}
{"pmid": "21007281", "title": "The general treatment of arthritis.", "content": "The general treatment of arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007281"}
{"pmid": "21007282", "title": "Bronchiectasis.", "content": "Bronchiectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007282"}
{"pmid": "21007284", "title": "Artificially-induced remission in a case of subacute bacterial endocarditis.", "content": "Artificially-induced remission in a case of subacute bacterial endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007284"}
{"pmid": "21007283", "title": "Pseudomyxoma peritonaei in a man following rupture of a retrocecal mucocele.", "content": "Pseudomyxoma peritonaei in a man following rupture of a retrocecal mucocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007283"}
{"pmid": "21007286", "title": "Surgical shock; an experimental study of its aetiology.", "content": "Surgical shock; an experimental study of its aetiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007286"}
{"pmid": "21007285", "title": "Postmortem examinations.", "content": "Postmortem examinations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007285"}
{"pmid": "21007288", "title": "Ten year planning in tuberculosis; with special reference to Mysore.", "content": "Ten year planning in tuberculosis; with special reference to Mysore.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007288"}
{"pmid": "21007289", "title": "So-called tropical ulcer in Angul.", "content": "So-called tropical ulcer in Angul.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007289"}
{"pmid": "21007287", "title": "Sulphathiazole and sulphaguanidine in the treatment of bacillary dysentery.", "content": "Sulphathiazole and sulphaguanidine in the treatment of bacillary dysentery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007287"}
{"pmid": "21007291", "title": "Atypical meningococcal meningitis.", "content": "Atypical meningococcal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007291"}
{"pmid": "21007290", "title": "Medical education.", "content": "Medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007290"}
{"pmid": "21007292", "title": "DEATH and disease in the Bengal famine.", "content": "DEATH and disease in the Bengal famine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007292"}
{"pmid": "21007293", "title": "A comparison of the results obtained with the Hanger caphalin-cholesterol flocculation test and the Maclagan thymol turbidity test in patients with liver disease.", "content": "A comparison of the results obtained with the Hanger caphalin-cholesterol flocculation test and the Maclagan thymol turbidity test in patients with liver disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007293"}
{"pmid": "21007294", "title": "Antigenic properties of various lipoids from beef heart.", "content": "Antigenic properties of various lipoids from beef heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007294"}
{"pmid": "21007295", "title": "A study of the relative sensitivity of different lots of antigen employed in the serologic tests for syphilis.", "content": "A study of the relative sensitivity of different lots of antigen employed in the serologic tests for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007295"}
{"pmid": "21007296", "title": "Theory of the colloidal gold reaction; reactions between gold sol and isolated protein fractions.", "content": "Theory of the colloidal gold reaction; reactions between gold sol and isolated protein fractions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007296"}
{"pmid": "21007297", "title": "Experimental production of pulmonary embolism by the use of a venous catheter.", "content": "Experimental production of pulmonary embolism by the use of a venous catheter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007297"}
{"pmid": "21007298", "title": "Penicillin combined with fever therapy; a preliminary report of twenty cases of early syphilis.", "content": "Penicillin combined with fever therapy; a preliminary report of twenty cases of early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007298"}
{"pmid": "21007299", "title": "Penicillin therapy in human bartonellosis (Carrion's disease).", "content": "Penicillin therapy in human bartonellosis (Carrion's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007299"}
{"pmid": "21007301", "title": "Hydrolyzed casein (capain) as a plasma substitute.", "content": "Hydrolyzed casein (capain) as a plasma substitute.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007301"}
{"pmid": "21007300", "title": "A standardised back burn procedure for the white rat suitable for the study of the effects of therapeutic and toxic agents on long-term survival.", "content": "A standardised back burn procedure for the white rat suitable for the study of the effects of therapeutic and toxic agents on long-term survival.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007300"}
{"pmid": "21007302", "title": "Studies on hypertension; effect of high spinal anesthesia on the blood pressure of patients with hypertension and far-advanced renal disease; its possible relationship to the pathogenesis of hypertension.", "content": "Studies on hypertension; effect of high spinal anesthesia on the blood pressure of patients with hypertension and far-advanced renal disease; its possible relationship to the pathogenesis of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007302"}
{"pmid": "21007303", "title": "The effect of intravenous typhoid vaccine on the intravenous glucose tolerance test.", "content": "The effect of intravenous typhoid vaccine on the intravenous glucose tolerance test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007303"}
{"pmid": "21007305", "title": "The urinary excretion of antipernicious anemia factor.", "content": "The urinary excretion of antipernicious anemia factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007305"}
{"pmid": "21007304", "title": "The diagnosis of enterobiasis; comparative study of the Graham and Hall techniques in the diagnoses of enterobiasis.", "content": "The diagnosis of enterobiasis; comparative study of the Graham and Hall techniques in the diagnoses of enterobiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007304"}
{"pmid": "21007306", "title": "The activity of synthetic Lactobacillus casei factor (folic acid) as an antipernicious anemia substance; observations on four patients; two with Addisonian pernicious anemia, one with montropical sprue and one with pernicious anemia of pregnancy.", "content": "The activity of synthetic Lactobacillus casei factor (folic acid) as an antipernicious anemia substance; observations on four patients; two with Addisonian pernicious anemia, one with montropical sprue and one with pernicious anemia of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007306"}
{"pmid": "21007307", "title": "A note on gastric retention in one-hour, two-dose glucose tolerance tests.", "content": "A note on gastric retention in one-hour, two-dose glucose tolerance tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007307"}
{"pmid": "21007308", "title": "Photoelectric determination of blood thiocyanates without precipitation of proteins.", "content": "Photoelectric determination of blood thiocyanates without precipitation of proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007308"}
{"pmid": "21007309", "title": "A colorimetric determination of paraldehyde.", "content": "A colorimetric determination of paraldehyde.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007309"}
{"pmid": "21007310", "title": "The J.S.B. stain for blood parasites.", "content": "The J.S.B. stain for blood parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007310"}
{"pmid": "21007311", "title": "Nutritional recovery following removal of all but three feet of jejunum and half of the colon.", "content": "Nutritional recovery following removal of all but three feet of jejunum and half of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007311"}
{"pmid": "21007312", "title": "Malignant melanoma case report.", "content": "Malignant melanoma case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007312"}
{"pmid": "21007313", "title": "Agnogenic myeloid metaplasia involving the bone marrow, liver, spleen and lymph nodes case report.", "content": "Agnogenic myeloid metaplasia involving the bone marrow, liver, spleen and lymph nodes case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007313"}
{"pmid": "21007314", "title": "What the general practitioner should know about leprosy.", "content": "What the general practitioner should know about leprosy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007314"}
{"pmid": "21007315", "title": "Operative management of ingrown toenail.", "content": "Operative management of ingrown toenail.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007315"}
{"pmid": "21007317", "title": "The diagnosis of thromboangiitis obliterans and peripheral arteriosclerosis.", "content": "The diagnosis of thromboangiitis obliterans and peripheral arteriosclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007317"}
{"pmid": "21007316", "title": "Penicillin in the treatment of gonorrhea.", "content": "Penicillin in the treatment of gonorrhea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007316"}
{"pmid": "21007320", "title": "Amyloid disease of the kidney.", "content": "Amyloid disease of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007320"}
{"pmid": "21007318", "title": "Polyradiculoneuritis case report.", "content": "Polyradiculoneuritis case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007318"}
{"pmid": "21007321", "title": "Blastomycosis involving the lungs, adrenals, kidneys, periprostatic tissue, right epididymis, testicle and vas deferens and seminal vesicles; case report.", "content": "Blastomycosis involving the lungs, adrenals, kidneys, periprostatic tissue, right epididymis, testicle and vas deferens and seminal vesicles; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007321"}
{"pmid": "21007319", "title": "For acquired hemolytic icterus nontraumatic emergency splenectomy.", "content": "For acquired hemolytic icterus nontraumatic emergency splenectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007319"}
{"pmid": "21007323", "title": "Clinical experiences with thiouracil.", "content": "Clinical experiences with thiouracil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007323"}
{"pmid": "21007322", "title": "Missouri medicine aims rehabilitation of indigent physically impaired.", "content": "Missouri medicine aims rehabilitation of indigent physically impaired.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007322"}
{"pmid": "21007324", "title": "Relapsing febrile nodular nonsuppurative panniculitis; with a report of a case.", "content": "Relapsing febrile nodular nonsuppurative panniculitis; with a report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007324"}
{"pmid": "21007325", "title": "The high frequency currents in surgery.", "content": "The high frequency currents in surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007325"}
{"pmid": "21007326", "title": "Fibrosis of the pancreatic ducts case report.", "content": "Fibrosis of the pancreatic ducts case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007326"}
{"pmid": "21007327", "title": "Diseases of the bile duct.", "content": "Diseases of the bile duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007327"}
{"pmid": "21007329", "title": "The Barnard Free Skin and Cancer Hospital; research report for 1944.", "content": "The Barnard Free Skin and Cancer Hospital; research report for 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007329"}
{"pmid": "21007331", "title": "Enrichment of bread.", "content": "Enrichment of bread.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007331"}
{"pmid": "21007330", "title": "Bronchoscopy; its role in the diagnosis and treatment of pulmonary tuberculosis.", "content": "Bronchoscopy; its role in the diagnosis and treatment of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007330"}
{"pmid": "21007328", "title": "Carcinoma of the prostate gland, and benefits of diethylstilbestrol or orchiectomy.", "content": "Carcinoma of the prostate gland, and benefits of diethylstilbestrol or orchiectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007328"}
{"pmid": "21007333", "title": "The patient diagnoses the doctor.", "content": "The patient diagnoses the doctor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007333"}
{"pmid": "21007332", "title": "Thiouracil; its use in hyperthyroidism.", "content": "Thiouracil; its use in hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007332"}
{"pmid": "21007334", "title": "Intestinal obstruction; two cases of unusual etiology.", "content": "Intestinal obstruction; two cases of unusual etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007334"}
{"pmid": "21007335", "title": "Continuous drip pentothal sodium with supplementary anesthesia.", "content": "Continuous drip pentothal sodium with supplementary anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007335"}
{"pmid": "21007336", "title": "Industrial health; recent developments in pneumoconiosis.", "content": "Industrial health; recent developments in pneumoconiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007336"}
{"pmid": "21007337", "title": "Tuberculosis in industry.", "content": "Tuberculosis in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007337"}
{"pmid": "21007339", "title": "Pneumatic rupture of the colon.", "content": "Pneumatic rupture of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007339"}
{"pmid": "21007338", "title": "Occupational dermatoses.", "content": "Occupational dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007338"}
{"pmid": "21007340", "title": "Environmental control of occupational disease.", "content": "Environmental control of occupational disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007340"}
{"pmid": "21007342", "title": "Industrial health activities in St. Louis.", "content": "Industrial health activities in St. Louis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007342"}
{"pmid": "21007343", "title": "The surgical care of the operable malignant lesions of the stomach.", "content": "The surgical care of the operable malignant lesions of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007343"}
{"pmid": "21007341", "title": "General program of the industrial hygiene services in Missouri.", "content": "General program of the industrial hygiene services in Missouri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007341"}
{"pmid": "21007344", "title": "Chemotherapeutic and surgical treatment of acute osteomelitis.", "content": "Chemotherapeutic and surgical treatment of acute osteomelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007344"}
{"pmid": "21007349", "title": "EFFECT of large doses of alkali on kidney function.", "content": "EFFECT of large doses of alkali on kidney function.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007349"}
{"pmid": "21007348", "title": "Ambulatory treatment of early syphilis with penicillin; rationale, experimental basis, and preliminary results.", "content": "Ambulatory treatment of early syphilis with penicillin; rationale, experimental basis, and preliminary results.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007348"}
{"pmid": "21007347", "title": "Retropubic prostatectomy; a new extravesical technique; report of 20 cases.", "content": "Retropubic prostatectomy; a new extravesical technique; report of 20 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007347"}
{"pmid": "21007350", "title": "Effect of penicillin on Bacillus proteus.", "content": "Effect of penicillin on Bacillus proteus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007350"}
{"pmid": "21007351", "title": "Acute brachial radiculitis; course and prognosis.", "content": "Acute brachial radiculitis; course and prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007351"}
{"pmid": "21007355", "title": "STAFFING of county hospitals.", "content": "STAFFING of county hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007355"}
{"pmid": "21007352", "title": "Extensive interstitial calcinosis, with osteoporesis and scleroderma-dermatomyositis.", "content": "Extensive interstitial calcinosis, with osteoporesis and scleroderma-dermatomyositis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007352"}
{"pmid": "21007353", "title": "ATYPICAL lichen planus and mepacrine.", "content": "ATYPICAL lichen planus and mepacrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007353"}
{"pmid": "21007356", "title": "Normal life of the red cell.", "content": "Normal life of the red cell.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007356"}
{"pmid": "21007354", "title": "OCCUPATION at a glance.", "content": "OCCUPATION at a glance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007354"}
{"pmid": "21007357", "title": "Hospital, industry, and the injured man; a surgeon's thoughts on rehabilitation.", "content": "Hospital, industry, and the injured man; a surgeon's thoughts on rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007357"}
{"pmid": "21007358", "title": "Resettlement of the disabled.", "content": "Resettlement of the disabled.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007358"}
{"pmid": "21007359", "title": "Clinical value of muscle biopsies.", "content": "Clinical value of muscle biopsies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007359"}
{"pmid": "21007360", "title": "Exposure of posterior horn of medial meniscus.", "content": "Exposure of posterior horn of medial meniscus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007360"}
{"pmid": "21007361", "title": "Thrombocytopenic purpura with normal bleeding-time.", "content": "Thrombocytopenic purpura with normal bleeding-time.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007361"}
{"pmid": "21007362", "title": "Probable relapse of malignant tertian malaria after thirteen years.", "content": "Probable relapse of malignant tertian malaria after thirteen years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007362"}
{"pmid": "21007363", "title": "Orthopaedic treatment of ankylosing spondylitis.", "content": "Orthopaedic treatment of ankylosing spondylitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007363"}
{"pmid": "21007368", "title": "POST-WAR bread policy.", "content": "POST-WAR bread policy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007368"}
{"pmid": "21007365", "title": "Polyvinyl alcohol as a medium for local penicillin therapy.", "content": "Polyvinyl alcohol as a medium for local penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007365"}
{"pmid": "21007366", "title": "BOVINE infection and disease.", "content": "BOVINE infection and disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007366"}
{"pmid": "21007364", "title": "Louse-borne relapsing fever treated with calcium gold keratinate.", "content": "Louse-borne relapsing fever treated with calcium gold keratinate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007364"}
{"pmid": "21007367", "title": "Assessment of industrial disability.", "content": "Assessment of industrial disability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007367"}
{"pmid": "21007370", "title": "Intestinal obstruction.", "content": "Intestinal obstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007370"}
{"pmid": "21007372", "title": "Influenzal meningitis.", "content": "Influenzal meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007372"}
{"pmid": "21007369", "title": "Retropubic prostatectomy.", "content": "Retropubic prostatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007369"}
{"pmid": "21007371", "title": "A case of psychosomatic interest.", "content": "A case of psychosomatic interest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007371"}
{"pmid": "21007373", "title": "German war surgery.", "content": "German war surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007373"}
{"pmid": "21007374", "title": "Polycythemia vera.", "content": "Polycythemia vera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007374"}
{"pmid": "21007377", "title": "Idiopathic methemoglobinemia.", "content": "Idiopathic methemoglobinemia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007377"}
{"pmid": "21007375", "title": "Perforated gallbladder; paralytic illus.", "content": "Perforated gallbladder; paralytic illus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007375"}
{"pmid": "21007376", "title": "Caricinoma of ovary in a child.", "content": "Caricinoma of ovary in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007376"}
{"pmid": "21007379", "title": "DOCTORS and saints.", "content": "DOCTORS and saints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007379"}
{"pmid": "21007378", "title": "Giant cell tumor of the ulna with excision and reconstruction.", "content": "Giant cell tumor of the ulna with excision and reconstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007378"}
{"pmid": "21007380", "title": "The typical headache of essential hypertension.", "content": "The typical headache of essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007380"}
{"pmid": "21007381", "title": "The surgical treatment of varicose veins; retrogade catheter method.", "content": "The surgical treatment of varicose veins; retrogade catheter method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007381"}
{"pmid": "21007383", "title": "The causalgic state; early and fixed lesions.", "content": "The causalgic state; early and fixed lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007383"}
{"pmid": "21007382", "title": "A transverse incision for gallbladder surgery.", "content": "A transverse incision for gallbladder surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007382"}
{"pmid": "21007384", "title": "Dysenteries.", "content": "Dysenteries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007384"}
{"pmid": "21007385", "title": "Eosinophilia and eosinophilic lungs.", "content": "Eosinophilia and eosinophilic lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007385"}
{"pmid": "21007386", "title": "Effort syndrome.", "content": "Effort syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007386"}
{"pmid": "21007387", "title": "Treatment of thromboangitis obliterans.", "content": "Treatment of thromboangitis obliterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007387"}
{"pmid": "21007388", "title": "Practical hints for judging and treating acute comatose conditions.", "content": "Practical hints for judging and treating acute comatose conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007388"}
{"pmid": "21007389", "title": "Vitamin therapy.", "content": "Vitamin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007389"}
{"pmid": "21007390", "title": "Pantothenic acid in animal nutrition.", "content": "Pantothenic acid in animal nutrition.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007390"}
{"pmid": "21007391", "title": "Vitamins, their role in pregnancy.", "content": "Vitamins, their role in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007391"}
{"pmid": "21007392", "title": "Cerebral injury by blunt mechanical trauma; review of literature.", "content": "Cerebral injury by blunt mechanical trauma; review of literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007392"}
{"pmid": "21007393", "title": "The absorption and elimination of gases of the body in relation to its fat and water content.", "content": "The absorption and elimination of gases of the body in relation to its fat and water content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007393"}
{"pmid": "21007395", "title": "Circulation and respiration in fever.", "content": "Circulation and respiration in fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007395"}
{"pmid": "21007394", "title": "Decompression sickness incident to deep sea diving and high altitude ascent.", "content": "Decompression sickness incident to deep sea diving and high altitude ascent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007394"}
{"pmid": "21007396", "title": "Radiology in the diagnosis of dyspepsia.", "content": "Radiology in the diagnosis of dyspepsia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007396"}
{"pmid": "21007397", "title": "Childbirth as an athletic feat.", "content": "Childbirth as an athletic feat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007397"}
{"pmid": "21007398", "title": "Second thoughts on soil fertility and dental caries.", "content": "Second thoughts on soil fertility and dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007398"}
{"pmid": "21007400", "title": "The diet of dyspeptics.", "content": "The diet of dyspeptics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007400"}
{"pmid": "21007399", "title": "Suggestion in medicine.", "content": "Suggestion in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007399"}
{"pmid": "21007401", "title": "The relation of septal deflections to rhinoplasty.", "content": "The relation of septal deflections to rhinoplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007401"}
{"pmid": "21007404", "title": "Hiccup.", "content": "Hiccup.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007404"}
{"pmid": "21007402", "title": "Hemorrhoids associated with nervous indigestion.", "content": "Hemorrhoids associated with nervous indigestion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007402"}
{"pmid": "21007403", "title": "Penicillin instillations in chronic otitis media and sinus infections; clinical appraisal, preliminary report.", "content": "Penicillin instillations in chronic otitis media and sinus infections; clinical appraisal, preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007403"}
{"pmid": "21007406", "title": "[Physical methods of treatment of the disabled of the Patriotic War in the polyclinics and health stations].", "content": "[Physical methods of treatment of the disabled of the Patriotic War in the polyclinics and health stations].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007406"}
{"pmid": "21007405", "title": "Should ordinary hospitals be used as medical schools?", "content": "Should ordinary hospitals be used as medical schools?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007405"}
{"pmid": "21007409", "title": "[The proper surgical treatment of small lesions].", "content": "[The proper surgical treatment of small lesions].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007409"}
{"pmid": "21007408", "title": "[Experience in a medico-evacuation service of a specialized hospital].", "content": "[Experience in a medico-evacuation service of a specialized hospital].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007408"}
{"pmid": "21007407", "title": "[On medical prosthesis].", "content": "[On medical prosthesis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007407"}
{"pmid": "21007410", "title": "[Adaptation of the regimen in educational work with delicate children in the nurseries].", "content": "[Adaptation of the regimen in educational work with delicate children in the nurseries].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007410"}
{"pmid": "21007411", "title": "[Dysentery in children and measures for its control in the health stations].", "content": "[Dysentery in children and measures for its control in the health stations].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007411"}
{"pmid": "21007412", "title": "[The clinics and prophylaxis of congenital syphilis].", "content": "[The clinics and prophylaxis of congenital syphilis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007412"}
{"pmid": "21007413", "title": "[The work of malaria control officials in the villages].", "content": "[The work of malaria control officials in the villages].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007413"}
{"pmid": "21007414", "title": "Rheumatic fever as a public health problem.", "content": "Rheumatic fever as a public health problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007414"}
{"pmid": "21007415", "title": "Medical non-missionaries.", "content": "Medical non-missionaries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007415"}
{"pmid": "21007416", "title": "Woman's Medical College of Pennsylvania, 1888-1900.", "content": "Woman's Medical College of Pennsylvania, 1888-1900.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007416"}
{"pmid": "21007417", "title": "Dawn brings new courage; in China, the story of a medical missionary.", "content": "Dawn brings new courage; in China, the story of a medical missionary.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007417"}
{"pmid": "21007418", "title": "The work of an English cancer hospital during the war.", "content": "The work of an English cancer hospital during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007418"}
{"pmid": "21007419", "title": "Modern trends in burn therapy as seen by the British.", "content": "Modern trends in burn therapy as seen by the British.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007419"}
{"pmid": "21007420", "title": "The coming new order in medical practice.", "content": "The coming new order in medical practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007420"}
{"pmid": "21007421", "title": "The problems of nursing in the rural hospital.", "content": "The problems of nursing in the rural hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007421"}
{"pmid": "21007422", "title": "Proper approach to geriatrics.", "content": "Proper approach to geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007422"}
{"pmid": "21007423", "title": "Combined treatment in gonorrhea cases.", "content": "Combined treatment in gonorrhea cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007423"}
{"pmid": "21007424", "title": "GASTRIC mucosal atrophy and carcinoma of the stomach.", "content": "GASTRIC mucosal atrophy and carcinoma of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007424"}
{"pmid": "21007426", "title": "Some conditions which may be confused with an anginal syndrome.", "content": "Some conditions which may be confused with an anginal syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007426"}
{"pmid": "21007427", "title": "Mediastinal cysts.", "content": "Mediastinal cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007427"}
{"pmid": "21007425", "title": "The treatment of strabismus in children.", "content": "The treatment of strabismus in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007425"}
{"pmid": "21007428", "title": "The treatment of major burns in naval warfare.", "content": "The treatment of major burns in naval warfare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007428"}
{"pmid": "21007429", "title": "Penicillin aerosolization in the treatment of serious respiratory infections; a preliminary report.", "content": "Penicillin aerosolization in the treatment of serious respiratory infections; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007429"}
{"pmid": "21007431", "title": "Serologic types of hemolytic streptococci in scarlet fever in Massachusetts.", "content": "Serologic types of hemolytic streptococci in scarlet fever in Massachusetts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007431"}
{"pmid": "21007430", "title": "Clinical and laboratory studies of ninety-one workers with apical systolic murmurs.", "content": "Clinical and laboratory studies of ninety-one workers with apical systolic murmurs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007430"}
{"pmid": "21007432", "title": "Hemoglobinemia and the hemoglobinurias.", "content": "Hemoglobinemia and the hemoglobinurias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007432"}
{"pmid": "21007433", "title": "Acute hemorrhagic interstitial pneumonia.", "content": "Acute hemorrhagic interstitial pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007433"}
{"pmid": "21007434", "title": "Glioblastoma multiforme of medulla.", "content": "Glioblastoma multiforme of medulla.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007434"}
{"pmid": "21007435", "title": "INFLUENZA.", "content": "INFLUENZA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007435"}
{"pmid": "21007437", "title": "Thiouracil as a cause of neutropenia and agranulocytosis.", "content": "Thiouracil as a cause of neutropenia and agranulocytosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007437"}
{"pmid": "21007436", "title": "Primary anastomosis in carcinoma of the colon.", "content": "Primary anastomosis in carcinoma of the colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007436"}
{"pmid": "21007438", "title": "The clinical significance of data accumulated in the medical care of young women.", "content": "The clinical significance of data accumulated in the medical care of young women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007438"}
{"pmid": "21007439", "title": "Menstruation, its disorders and their treatment.", "content": "Menstruation, its disorders and their treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007439"}
{"pmid": "21007440", "title": "Subacute and chronic glomerulonephritis developing in congenital polycystic kidneys.", "content": "Subacute and chronic glomerulonephritis developing in congenital polycystic kidneys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007440"}
{"pmid": "21007441", "title": "Acute pancreatitis, with fat necrosis.", "content": "Acute pancreatitis, with fat necrosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007441"}
{"pmid": "21007442", "title": "Toxoplasmic encephalitis; clinical findings in two patients from Pacific Northwest.", "content": "Toxoplasmic encephalitis; clinical findings in two patients from Pacific Northwest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007442"}
{"pmid": "21007444", "title": "Typhus fever.", "content": "Typhus fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007444"}
{"pmid": "21007443", "title": "Melanoma of small intestine.", "content": "Melanoma of small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007443"}
{"pmid": "21007445", "title": "Necessary cooperation of all physicians.", "content": "Necessary cooperation of all physicians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007445"}
{"pmid": "21007446", "title": "Present and future prepayment plans.", "content": "Present and future prepayment plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007446"}
{"pmid": "21007447", "title": "The Medical Service Bureau an answer to socialized medicine.", "content": "The Medical Service Bureau an answer to socialized medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007447"}
{"pmid": "21007448", "title": "Extraperitoneal cesarean section; with special reference to the Waters technic.", "content": "Extraperitoneal cesarean section; with special reference to the Waters technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007448"}
{"pmid": "21007449", "title": "Clinical study of 15 cases of sinusitis.", "content": "Clinical study of 15 cases of sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007449"}
{"pmid": "21007450", "title": "Treatment of blood dyscrasias.", "content": "Treatment of blood dyscrasias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007450"}
{"pmid": "21007451", "title": "Occurrence of Bacillus welchiigas gangrene at site of penicillin intramuscular clyses.", "content": "Occurrence of Bacillus welchiigas gangrene at site of penicillin intramuscular clyses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007451"}
{"pmid": "21007452", "title": "The use of the mercurial diuretics.", "content": "The use of the mercurial diuretics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007452"}
{"pmid": "21007453", "title": "CARDIOLOGY.", "content": "CARDIOLOGY.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007453"}
{"pmid": "21007455", "title": "Discussion on so-called rheumatism.", "content": "Discussion on so-called rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007455"}
{"pmid": "21007454", "title": "The treatment of simple and toxic enlargements of the thyroid gland.", "content": "The treatment of simple and toxic enlargements of the thyroid gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007454"}
{"pmid": "21007462", "title": "The beginnings or asepsis; the story of a tragic life.", "content": "The beginnings or asepsis; the story of a tragic life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007462"}
{"pmid": "21007463", "title": "Necropsies in the hospitals of Chicago.", "content": "Necropsies in the hospitals of Chicago.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007463"}
{"pmid": "21007464", "title": "Annual report of Section on Radium Therapy for 1944.", "content": "Annual report of Section on Radium Therapy for 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007464"}
{"pmid": "21007465", "title": "Neurofibromatosis with sarcoma of leg; report of case.", "content": "Neurofibromatosis with sarcoma of leg; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007465"}
{"pmid": "21007466", "title": "Notes on a modified open-circuit method for the measurement of residual air.", "content": "Notes on a modified open-circuit method for the measurement of residual air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007466"}
{"pmid": "21007467", "title": "The crying of newly born babies; the individual phase.", "content": "The crying of newly born babies; the individual phase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007467"}
{"pmid": "21007468", "title": "Annual report of Gynecologic Surgery for 1944.", "content": "Annual report of Gynecologic Surgery for 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007468"}
{"pmid": "21007470", "title": "Transthoracic resection of lesions of the lower portion of the esophagus and the cardia of the stomach.", "content": "Transthoracic resection of lesions of the lower portion of the esophagus and the cardia of the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007470"}
{"pmid": "21007471", "title": "Report of genito-urinary surgery for 1944.", "content": "Report of genito-urinary surgery for 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007471"}
{"pmid": "21007469", "title": "The expanding field of physical medicine.", "content": "The expanding field of physical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007469"}
{"pmid": "21007478", "title": "The diagnosis and primary surgical treatment of injuries of the hand.", "content": "The diagnosis and primary surgical treatment of injuries of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007478"}
{"pmid": "21007460", "title": "Social psychiatry in the post-war world.", "content": "Social psychiatry in the post-war world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007460"}
{"pmid": "21007461", "title": "Discussion on the use and abuse of manipulative surgery.", "content": "Discussion on the use and abuse of manipulative surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007461"}
{"pmid": "21007459", "title": "Transport of casualties by air.", "content": "Transport of casualties by air.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007459"}
{"pmid": "21007479", "title": "Hormones in tuberculosis.", "content": "Hormones in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007479"}
{"pmid": "21007458", "title": "Experiences as an Army physician in Malta and Sicily.", "content": "Experiences as an Army physician in Malta and Sicily.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007458"}
{"pmid": "21007480", "title": "Penicillin treatment of early syphilis.", "content": "Penicillin treatment of early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007480"}
{"pmid": "21007481", "title": "FUTURE of industrial medicine in Rhode Island.", "content": "FUTURE of industrial medicine in Rhode Island.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007481"}
{"pmid": "21007457", "title": "Shall we nationalize medicine?", "content": "Shall we nationalize medicine?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007457"}
{"pmid": "21007483", "title": "Sodium pentothal anesthesia.", "content": "Sodium pentothal anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007483"}
{"pmid": "21007485", "title": "Technical pitfalls in thyroid surgery.", "content": "Technical pitfalls in thyroid surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007485"}
{"pmid": "21007484", "title": "Skiodan as a contrast medium in utero-salpingography.", "content": "Skiodan as a contrast medium in utero-salpingography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007484"}
{"pmid": "21007482", "title": "The Rhode Island second injury fund.", "content": "The Rhode Island second injury fund.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007482"}
{"pmid": "21007486", "title": "Clinical comparison of methergine and natural ergonovine.", "content": "Clinical comparison of methergine and natural ergonovine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007486"}
{"pmid": "21007487", "title": "FAILURE OF vitamin K as an antidote in dicumarol poisoning.", "content": "FAILURE OF vitamin K as an antidote in dicumarol poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007487"}
{"pmid": "21007489", "title": "The forward surgery of abdominal war wounds.", "content": "The forward surgery of abdominal war wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007489"}
{"pmid": "21007488", "title": "Prospect for the future control of tuberculosis.", "content": "Prospect for the future control of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007488"}
{"pmid": "21007491", "title": "Tuberculose: aphorismen en consequenties.", "content": "Tuberculose: aphorismen en consequenties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007491"}
{"pmid": "21007492", "title": "Succulent collecting.", "content": "Succulent collecting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007492"}
{"pmid": "21007490", "title": "A common antigenic factor between B. typhosus and B. dysenteriae Flexner.", "content": "A common antigenic factor between B. typhosus and B. dysenteriae Flexner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007490"}
{"pmid": "21007493", "title": "The sickle-cell trait in the South African Bantu.", "content": "The sickle-cell trait in the South African Bantu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007493"}
{"pmid": "21007456", "title": "The significance of hoarseness.", "content": "The significance of hoarseness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007456"}
{"pmid": "21007521", "title": "Sydenham's chorea.", "content": "Sydenham's chorea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007521"}
{"pmid": "21007522", "title": "Deep volar arch.", "content": "Deep volar arch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007522"}
{"pmid": "21007523", "title": "The mode of action of sulfonamides.", "content": "The mode of action of sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007523"}
{"pmid": "21007524", "title": "Thiouracil: its present status in the treatment of hyperthyroidism.", "content": "Thiouracil: its present status in the treatment of hyperthyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007524"}
{"pmid": "21007525", "title": "Early ambulation of the post-operative patient; a review of current literature.", "content": "Early ambulation of the post-operative patient; a review of current literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007525"}
{"pmid": "21007526", "title": "Fluid requirements of the surgical patient.", "content": "Fluid requirements of the surgical patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007526"}
{"pmid": "21007531", "title": "Some strange tumors.", "content": "Some strange tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007531"}
{"pmid": "21007532", "title": "Postoperative pneumonia and atelectasis.", "content": "Postoperative pneumonia and atelectasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007532"}
{"pmid": "21007533", "title": "Neckel's diverticulum; fifty-six cases.", "content": "Neckel's diverticulum; fifty-six cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007533"}
{"pmid": "21007534", "title": "The hyperpnea test for latent coronary artery disease; a preliminary report.", "content": "The hyperpnea test for latent coronary artery disease; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007534"}
{"pmid": "21007535", "title": "The control of hemorrhage after tonsillectomy; the use of thrombin.", "content": "The control of hemorrhage after tonsillectomy; the use of thrombin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007535"}
{"pmid": "21007537", "title": "Penicillin in the treatment of meningitis.", "content": "Penicillin in the treatment of meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007537"}
{"pmid": "21007538", "title": "Treatment of pilonidal cysts.", "content": "Treatment of pilonidal cysts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007538"}
{"pmid": "21007536", "title": "Bacterial endocarditis and penicillin; report of two cases with diabetes.", "content": "Bacterial endocarditis and penicillin; report of two cases with diabetes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007536"}
{"pmid": "21007539", "title": "The role of demerol in obstetrics.", "content": "The role of demerol in obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007539"}
{"pmid": "21007540", "title": "Renal hypertension; nephrectomies at Wisconsin General Hospital.", "content": "Renal hypertension; nephrectomies at Wisconsin General Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007540"}
{"pmid": "21007541", "title": "Streptococcus fecalis bacteremia and meningitis; report of a case cured with penicillin.", "content": "Streptococcus fecalis bacteremia and meningitis; report of a case cured with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007541"}
{"pmid": "21007542", "title": "The agglutination of staphylococcus aureus in the presence of normal or influenza virus-infected mouse lung filtrates and of chorio-allantoic fluids.", "content": "The agglutination of staphylococcus aureus in the presence of normal or influenza virus-infected mouse lung filtrates and of chorio-allantoic fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007542"}
{"pmid": "21007543", "title": "The Sturge-Weber syndrome; report of three cases.", "content": "The Sturge-Weber syndrome; report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007543"}
{"pmid": "21007544", "title": "On the development of the amnion and exoccelomic membrane in the previllous human ovum.", "content": "On the development of the amnion and exoccelomic membrane in the previllous human ovum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007544"}
{"pmid": "21007545", "title": "On the relation between discharge zone and subliminal fringe in a motoneuron pool supplied by a homogeneous presynaptic pathway.", "content": "On the relation between discharge zone and subliminal fringe in a motoneuron pool supplied by a homogeneous presynaptic pathway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007545"}
{"pmid": "21007546", "title": "STATUS of penicillin treatment of early syphilis.", "content": "STATUS of penicillin treatment of early syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007546"}
{"pmid": "21007547", "title": "Present status of homologous serum jaundice.", "content": "Present status of homologous serum jaundice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007547"}
{"pmid": "21007548", "title": "CORNEAL edema; unusual toxic reaction to atabrine.", "content": "CORNEAL edema; unusual toxic reaction to atabrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007548"}
{"pmid": "21007549", "title": "CIVILIAN survey of the Army's amputation program.", "content": "CIVILIAN survey of the Army's amputation program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007549"}
{"pmid": "21007550", "title": "EXTERNAL otitis in the tropics.", "content": "EXTERNAL otitis in the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007550"}
{"pmid": "21007551", "title": "LABORATORY aids in diagnosis of primary atypical pneumonia.", "content": "LABORATORY aids in diagnosis of primary atypical pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007551"}
{"pmid": "21007552", "title": "MODIFIED mosquito light trap.", "content": "MODIFIED mosquito light trap.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007552"}
{"pmid": "21007553", "title": "PROBLEM of burns in military surgery.", "content": "PROBLEM of burns in military surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007553"}
{"pmid": "21007554", "title": "STUDY of psychosomatic dermatological syndromes.", "content": "STUDY of psychosomatic dermatological syndromes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007554"}
{"pmid": "21007557", "title": "LABORATORY methods used for the recognition of influenza.", "content": "LABORATORY methods used for the recognition of influenza.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007557"}
{"pmid": "21007555", "title": "FELLOWSHIPS in medical research.", "content": "FELLOWSHIPS in medical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007555"}
{"pmid": "21007556", "title": "FLY control with DDT.", "content": "FLY control with DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007556"}
{"pmid": "21007558", "title": "DEATHS in American land forces during major wars.", "content": "DEATHS in American land forces during major wars.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007558"}
{"pmid": "21007560", "title": "PROPOSED postwar Medical Department plan.", "content": "PROPOSED postwar Medical Department plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007560"}
{"pmid": "21007559", "title": "Antistreptococcal antibodies.", "content": "Antistreptococcal antibodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007559"}
{"pmid": "21007561", "title": "GUIDES to historical writing.", "content": "GUIDES to historical writing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007561"}
{"pmid": "21007562", "title": "The medical approach to the patient in the Army.", "content": "The medical approach to the patient in the Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007562"}
{"pmid": "21007564", "title": "Nutritional aspects of care of paralyzed patients.", "content": "Nutritional aspects of care of paralyzed patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007564"}
{"pmid": "21007563", "title": "Balanced suspension and fractures of the femur.", "content": "Balanced suspension and fractures of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007563"}
{"pmid": "21007565", "title": "Simple method of removing vesical calculi in paraplegic patients.", "content": "Simple method of removing vesical calculi in paraplegic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007565"}
{"pmid": "21007566", "title": "Jaw relationship records; vertical dimension and centric.", "content": "Jaw relationship records; vertical dimension and centric.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007566"}
{"pmid": "21007567", "title": "Psychiatry in the Fifth Army area.", "content": "Psychiatry in the Fifth Army area.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007567"}
{"pmid": "21007568", "title": "Clinical experience with snake bites on Okinawa.", "content": "Clinical experience with snake bites on Okinawa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007568"}
{"pmid": "21007569", "title": "Treatment of patient at sea.", "content": "Treatment of patient at sea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007569"}
{"pmid": "21007570", "title": "Relation of the Weil-Felix reaction to the clinical course of Tsutsugamushi disease.", "content": "Relation of the Weil-Felix reaction to the clinical course of Tsutsugamushi disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007570"}
{"pmid": "21007571", "title": "Processing Del-Mar-Va poultry for the Armed Forces.", "content": "Processing Del-Mar-Va poultry for the Armed Forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007571"}
{"pmid": "21007572", "title": "Bacterial flora in cantonment-type surgical ward.", "content": "Bacterial flora in cantonment-type surgical ward.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007572"}
{"pmid": "21007573", "title": "Radiation characteristics of the field x-ray unit used for superficial therapy.", "content": "Radiation characteristics of the field x-ray unit used for superficial therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007573"}
{"pmid": "21007574", "title": "A clinical test of nerve regeneration.", "content": "A clinical test of nerve regeneration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007574"}
{"pmid": "21007575", "title": "Stevens-Johnson's disease in edentulous mouth; report of case.", "content": "Stevens-Johnson's disease in edentulous mouth; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007575"}
{"pmid": "21007576", "title": "The detection of methanol in blood-methanol mixtures; preliminary note.", "content": "The detection of methanol in blood-methanol mixtures; preliminary note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007576"}
{"pmid": "21007579", "title": "Brucellosis.", "content": "Brucellosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007579"}
{"pmid": "21007577", "title": "Methyl alcohol poisoning; report of cases.", "content": "Methyl alcohol poisoning; report of cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007577"}
{"pmid": "21007578", "title": "Analysis of advanced reconditioning cases.", "content": "Analysis of advanced reconditioning cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007578"}
{"pmid": "21007580", "title": "NEW powder for fungus infections.", "content": "NEW powder for fungus infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007580"}
{"pmid": "21007582", "title": "Marine art.", "content": "Marine art.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007582"}
{"pmid": "21007581", "title": "Foot care for your crew.", "content": "Foot care for your crew.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007581"}
{"pmid": "21007584", "title": "Biliary colic and chronic pancreatitis.", "content": "Biliary colic and chronic pancreatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007584"}
{"pmid": "21007583", "title": "Salt deficiency states in tropical climates.", "content": "Salt deficiency states in tropical climates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007583"}
{"pmid": "21007585", "title": "Pseudo-leukaemic eosinophilia complicated by gangrenous appendicitis, as a possible manifestation of infectious mononucleosis, with observations on the mutual antagnism between lymphocytes and granulocytes.", "content": "Pseudo-leukaemic eosinophilia complicated by gangrenous appendicitis, as a possible manifestation of infectious mononucleosis, with observations on the mutual antagnism between lymphocytes and granulocytes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007585"}
{"pmid": "21007586", "title": "Traumatic lesions of the spinal cord.", "content": "Traumatic lesions of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007586"}
{"pmid": "21007587", "title": "A summer tour in the Persian Gulf.", "content": "A summer tour in the Persian Gulf.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007587"}
{"pmid": "21007588", "title": "Remarks on acclimatization.", "content": "Remarks on acclimatization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007588"}
{"pmid": "21007589", "title": "A psychiatric survey of naval personnel.", "content": "A psychiatric survey of naval personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007589"}
{"pmid": "21007590", "title": "Recent advances in malaria control.", "content": "Recent advances in malaria control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007590"}
{"pmid": "21007593", "title": "Prickley heat and tropical pemphigus.", "content": "Prickley heat and tropical pemphigus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007593"}
{"pmid": "21007592", "title": "Traumatic aneurysm of the femoral artery.", "content": "Traumatic aneurysm of the femoral artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007592"}
{"pmid": "21007591", "title": "Apparent lack of response to quinine and mepacrine in cases of subtertian malaria.", "content": "Apparent lack of response to quinine and mepacrine in cases of subtertian malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007591"}
{"pmid": "21007594", "title": "Methods of accelerating dark adaptation and improving night vision.", "content": "Methods of accelerating dark adaptation and improving night vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007594"}
{"pmid": "21007595", "title": "Syndrome of oxygen poisoning in cats.", "content": "Syndrome of oxygen poisoning in cats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007595"}
{"pmid": "21007596", "title": "Development of psychiatry in the Army in World War II.", "content": "Development of psychiatry in the Army in World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007596"}
{"pmid": "21007597", "title": "Psychiatric study of 100 battle veterans.", "content": "Psychiatric study of 100 battle veterans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007597"}
{"pmid": "21007598", "title": "Psychiatry aboard a hospital ship during the attack on Pearl Harbor.", "content": "Psychiatry aboard a hospital ship during the attack on Pearl Harbor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007598"}
{"pmid": "21007599", "title": "Psychiatric disorders in Puerto Rican troops.", "content": "Psychiatric disorders in Puerto Rican troops.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007599"}
{"pmid": "21007600", "title": "Psychosis following administration of quinacrine hydrochloride for malaria; neuropsychiatric study of a case.", "content": "Psychosis following administration of quinacrine hydrochloride for malaria; neuropsychiatric study of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007600"}
{"pmid": "21007601", "title": "Delayed combat reactions in Air Force personnel.", "content": "Delayed combat reactions in Air Force personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007601"}
{"pmid": "21007602", "title": "Measurement of skin resistance in peripheral nerve injuries.", "content": "Measurement of skin resistance in peripheral nerve injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007602"}
{"pmid": "21007603", "title": "HAFFKINE INSTITUTE.", "content": "HAFFKINE INSTITUTE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007603"}
{"pmid": "21007604", "title": "Anew hypothesis for the mechanism of activation of substrate molecules by enzymes.", "content": "Anew hypothesis for the mechanism of activation of substrate molecules by enzymes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007604"}
{"pmid": "21007605", "title": "On dicoumarin-synthetic anti-coagulant.", "content": "On dicoumarin-synthetic anti-coagulant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007605"}
{"pmid": "21007606", "title": "A preliminary note on the antibacterial substance from Aspergillus flavus.", "content": "A preliminary note on the antibacterial substance from Aspergillus flavus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007606"}
{"pmid": "21007607", "title": "Studies in the sulphur formation at Kona, Masulipatam. II.", "content": "Studies in the sulphur formation at Kona, Masulipatam. II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007607"}
{"pmid": "21007608", "title": "Role of water-soluble phosphoric acid as an aspect of sewage irrigation.", "content": "Role of water-soluble phosphoric acid as an aspect of sewage irrigation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007608"}
{"pmid": "21007609", "title": "Occurrence of gossypol.", "content": "Occurrence of gossypol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007609"}
{"pmid": "21007610", "title": "Seed transmission of melon mosaic virus.", "content": "Seed transmission of melon mosaic virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007610"}
{"pmid": "21007611", "title": "Osteometric determination of sex from the head and the lower end of the femur.", "content": "Osteometric determination of sex from the head and the lower end of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007611"}
{"pmid": "21007612", "title": "On a new coccidium Wenyonella gallinae from the gut of the domestic fowl, Gallus gallus domesticus Linn.", "content": "On a new coccidium Wenyonella gallinae from the gut of the domestic fowl, Gallus gallus domesticus Linn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007612"}
{"pmid": "21007613", "title": "Determination of the purity of hydrocarbons by measurement of freezing points.", "content": "Determination of the purity of hydrocarbons by measurement of freezing points.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007613"}
{"pmid": "21007614", "title": "Second dissociation constant of o-phthalic acid and related pH values of phthalate buffers from 0 degrees to 60 degrees C.", "content": "Second dissociation constant of o-phthalic acid and related pH values of phthalate buffers from 0 degrees to 60 degrees C.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007614"}
{"pmid": "21007615", "title": "Oxidation of galacturonic acid and of 5-keto-gluconic acid in alkaline solution.", "content": "Oxidation of galacturonic acid and of 5-keto-gluconic acid in alkaline solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007615"}
{"pmid": "21007616", "title": "The mission of science.", "content": "The mission of science.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007616"}
{"pmid": "21007617", "title": "An electrical hypothesis of synaptic and neuromuscular transmission.", "content": "An electrical hypothesis of synaptic and neuromuscular transmission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007617"}
{"pmid": "21007618", "title": "Porphyrin fluorescence in the livers of pellagrins in relation to ultra-violet light.", "content": "Porphyrin fluorescence in the livers of pellagrins in relation to ultra-violet light.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007618"}
{"pmid": "21007619", "title": "Acetylphosphatase in animal tissues.", "content": "Acetylphosphatase in animal tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007619"}
{"pmid": "21007620", "title": "Use of growth-promoting substances in the prevention of apple drop following frost.", "content": "Use of growth-promoting substances in the prevention of apple drop following frost.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007620"}
{"pmid": "21007621", "title": "Acoustic control in the flight of bats.", "content": "Acoustic control in the flight of bats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007621"}
{"pmid": "21007622", "title": "Life-time of the neutral meson.", "content": "Life-time of the neutral meson.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007622"}
{"pmid": "21007623", "title": "Autoxidation of linoleic acid.", "content": "Autoxidation of linoleic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007623"}
{"pmid": "21007624", "title": "Primary degradation products of mepacrine in human urines.", "content": "Primary degradation products of mepacrine in human urines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007624"}
{"pmid": "21007625", "title": "Parathyroidectomy and lactation in the rat.", "content": "Parathyroidectomy and lactation in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007625"}
{"pmid": "21007626", "title": "Nature of the gram-positive complex in micro-organisms.", "content": "Nature of the gram-positive complex in micro-organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007626"}
{"pmid": "21007628", "title": "Hospital diet.", "content": "Hospital diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007628"}
{"pmid": "21007627", "title": "Excavations at Hyrax Hill, Nakuru, Kenya Colony.", "content": "Excavations at Hyrax Hill, Nakuru, Kenya Colony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007627"}
{"pmid": "21007629", "title": "Science and reconstruction.", "content": "Science and reconstruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007629"}
{"pmid": "21007630", "title": "The edibility of birds.", "content": "The edibility of birds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007630"}
{"pmid": "21007631", "title": "Experimental imitation of tumour conditions.", "content": "Experimental imitation of tumour conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007631"}
{"pmid": "21007632", "title": "Adsorption isotherms from chromatographic measurements.", "content": "Adsorption isotherms from chromatographic measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007632"}
{"pmid": "21007634", "title": "Differentiation of nuclear substances.", "content": "Differentiation of nuclear substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007634"}
{"pmid": "21007633", "title": "Efficacy of D.D.T. in soap.", "content": "Efficacy of D.D.T. in soap.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007633"}
{"pmid": "21007635", "title": "Cytological reactions induced by inorganic salt solutions.", "content": "Cytological reactions induced by inorganic salt solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007635"}
{"pmid": "21007637", "title": "Mode of entry of contact insecticides.", "content": "Mode of entry of contact insecticides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007637"}
{"pmid": "21007636", "title": "Carboxylase and carbonic acid.", "content": "Carboxylase and carbonic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007636"}
{"pmid": "21007639", "title": "Human chromosomes.", "content": "Human chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007639"}
{"pmid": "21007638", "title": "Ergot on Pennisetum Hohenackeri Hochst.", "content": "Ergot on Pennisetum Hohenackeri Hochst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007638"}
{"pmid": "21007640", "title": "A direct-reading photoelectric colorimeter.", "content": "A direct-reading photoelectric colorimeter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007640"}
{"pmid": "21007641", "title": "A simple refractoscope for liquids.", "content": "A simple refractoscope for liquids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007641"}
{"pmid": "21007642", "title": "A useful seal for dynamic vacuum systems.", "content": "A useful seal for dynamic vacuum systems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007642"}
{"pmid": "21007643", "title": "A refractometer.", "content": "A refractometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007643"}
{"pmid": "21007644", "title": "DOUBLE-BEAM cathode-ray tube.", "content": "DOUBLE-BEAM cathode-ray tube.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007644"}
{"pmid": "21007645", "title": "Who has the earth's uranium?", "content": "Who has the earth's uranium?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007645"}
{"pmid": "21007647", "title": "Science and the Government.", "content": "Science and the Government.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007647"}
{"pmid": "21007646", "title": "CHEMISTRY of penicillin.", "content": "CHEMISTRY of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007646"}
{"pmid": "21007648", "title": "Further studies on the monkey anti-anemia factor.", "content": "Further studies on the monkey anti-anemia factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007648"}
{"pmid": "21007649", "title": "Demonstration of influenza virus, Type B, in a recent outbreak of upper respiratory infection.", "content": "Demonstration of influenza virus, Type B, in a recent outbreak of upper respiratory infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007649"}
{"pmid": "21007650", "title": "Transmission of the toxicity of DDT through the milk of white rats and goats.", "content": "Transmission of the toxicity of DDT through the milk of white rats and goats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007650"}
{"pmid": "21007653", "title": "WARTIME research in malaria.", "content": "WARTIME research in malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007653"}
{"pmid": "21007651", "title": "A fog or aerosol applicator for DDT.", "content": "A fog or aerosol applicator for DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007651"}
{"pmid": "21007652", "title": "Science legislation.", "content": "Science legislation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007652"}
{"pmid": "21007654", "title": "Science legislation and the holiday recess.", "content": "Science legislation and the holiday recess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007654"}
{"pmid": "21007655", "title": "The lipotropic properties of inositol.", "content": "The lipotropic properties of inositol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007655"}
{"pmid": "21007656", "title": "TDE, 1,1-dichloro 2,2-bis (p-chlorophenyl) ethane, as an anopheline larvicide.", "content": "TDE, 1,1-dichloro 2,2-bis (p-chlorophenyl) ethane, as an anopheline larvicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007656"}
{"pmid": "21007657", "title": "Black fly incubator-aerator cabinet.", "content": "Black fly incubator-aerator cabinet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007657"}
{"pmid": "21007658", "title": "Attachment of electroencephalographic electrodes.", "content": "Attachment of electroencephalographic electrodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007658"}
{"pmid": "21007659", "title": "A new glass device for staining cover-glass preparations.", "content": "A new glass device for staining cover-glass preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007659"}
{"pmid": "21007660", "title": "Growth of trophoblast in the anterior chamber of the eye of the rabbit.", "content": "Growth of trophoblast in the anterior chamber of the eye of the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007660"}
{"pmid": "21007663", "title": "Electrical correlates of peripheral nerve injury; a preliminary note.", "content": "Electrical correlates of peripheral nerve injury; a preliminary note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007663"}
{"pmid": "21007661", "title": "Freezing behavior in rats.", "content": "Freezing behavior in rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007661"}
{"pmid": "21007662", "title": "New opportunities and new responsibilities for the psychologist.", "content": "New opportunities and new responsibilities for the psychologist.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007662"}
{"pmid": "21007664", "title": "Spinal conditioning in dogs.", "content": "Spinal conditioning in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007664"}
{"pmid": "21007665", "title": "A gastric mucigogue action of the alkyl sulfates.", "content": "A gastric mucigogue action of the alkyl sulfates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007665"}
{"pmid": "21007666", "title": "Degradation of streptomycin and the structure of streptidine and streptamine.", "content": "Degradation of streptomycin and the structure of streptidine and streptamine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007666"}
{"pmid": "21007667", "title": "A photographic method for recording ureteral kinetics in situ.", "content": "A photographic method for recording ureteral kinetics in situ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007667"}
{"pmid": "21007668", "title": "The estimation of streptomycin in body fluids.", "content": "The estimation of streptomycin in body fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007668"}
{"pmid": "21007669", "title": "Continuous anesthesia for insects.", "content": "Continuous anesthesia for insects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007669"}
{"pmid": "21007670", "title": "Ch'ang Shan, a Chinese antimalarial drug.", "content": "Ch'ang Shan, a Chinese antimalarial drug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007670"}
{"pmid": "21007671", "title": "State sterilization programs for the prophylactic control of mental disease and mental deficiency.", "content": "State sterilization programs for the prophylactic control of mental disease and mental deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007671"}
{"pmid": "21007672", "title": "Electroencephalographic study of criminals.", "content": "Electroencephalographic study of criminals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007672"}
{"pmid": "21007673", "title": "The correlation of pre-electroshock electroencephalogram and therapeutic result in schizophrenia.", "content": "The correlation of pre-electroshock electroencephalogram and therapeutic result in schizophrenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007673"}
{"pmid": "21007674", "title": "An electroencephalographic study of cases with syncope and related disorders.", "content": "An electroencephalographic study of cases with syncope and related disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007674"}
{"pmid": "21007675", "title": "The electroencephalogram in some military and selective service convulsive and non-convulsive problems.", "content": "The electroencephalogram in some military and selective service convulsive and non-convulsive problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007675"}
{"pmid": "21007676", "title": "Some reactions seen after electric shock treatment.", "content": "Some reactions seen after electric shock treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007676"}
{"pmid": "21007677", "title": "The prophylaxis of cardiac complications in electroshock therapy.", "content": "The prophylaxis of cardiac complications in electroshock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007677"}
{"pmid": "21007678", "title": "Organic and hysterical anesthesia; a method of differential diagnosis with the aid of the galvanic skin response.", "content": "Organic and hysterical anesthesia; a method of differential diagnosis with the aid of the galvanic skin response.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007678"}
{"pmid": "21007680", "title": "Psychoanalysis and the unconscious.", "content": "Psychoanalysis and the unconscious.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007680"}
{"pmid": "21007679", "title": "Ageing and detoxication; studies in hippuric acid synthesis during psychoses of the involutional and old age group.", "content": "Ageing and detoxication; studies in hippuric acid synthesis during psychoses of the involutional and old age group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007679"}
{"pmid": "21007682", "title": "Attitudes of soldiers returning from overseas service.", "content": "Attitudes of soldiers returning from overseas service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007682"}
{"pmid": "21007681", "title": "The personality of the successful soldier.", "content": "The personality of the successful soldier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007681"}
{"pmid": "21007683", "title": "A brief history of family care of mental patients in America.", "content": "A brief history of family care of mental patients in America.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007683"}
{"pmid": "21007684", "title": "A total psychotherapeutic push method as practiced in the Fifth Service Command Rehabilitation Center, Fort Knox, Kentucky.", "content": "A total psychotherapeutic push method as practiced in the Fifth Service Command Rehabilitation Center, Fort Knox, Kentucky.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007684"}
{"pmid": "21007685", "title": "Emotional adjustment of newly blinded soldiers.", "content": "Emotional adjustment of newly blinded soldiers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007685"}
{"pmid": "21007686", "title": "Conquering war strain in children.", "content": "Conquering war strain in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007686"}
{"pmid": "21007689", "title": "Some relationships between excitement, depression and anxiety.", "content": "Some relationships between excitement, depression and anxiety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007689"}
{"pmid": "21007690", "title": "Self-induced psychosis with hyperthyroidism complicating manic depressive psychosis.", "content": "Self-induced psychosis with hyperthyroidism complicating manic depressive psychosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007690"}
{"pmid": "21007687", "title": "The autobiographical study as an aid to psychotherapy.", "content": "The autobiographical study as an aid to psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007687"}
{"pmid": "21007688", "title": "The central nervous system in morphinism.", "content": "The central nervous system in morphinism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007688"}
{"pmid": "21007694", "title": "Discussion of Dr. Bassoe's article, Spain as the cradle of psychiatry.", "content": "Discussion of Dr. Bassoe's article, Spain as the cradle of psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007694"}
{"pmid": "21007693", "title": "Diagnosis and classification; a distinction.", "content": "Diagnosis and classification; a distinction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007693"}
{"pmid": "21007691", "title": "The autokinetic test; its value in psychiatric diagnosis and prognosis; preliminary report.", "content": "The autokinetic test; its value in psychiatric diagnosis and prognosis; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007691"}
{"pmid": "21007692", "title": "A note on apomorphine as a sedative.", "content": "A note on apomorphine as a sedative.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007692"}
{"pmid": "21007695", "title": "The psychiatry-anthropology relationship.", "content": "The psychiatry-anthropology relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007695"}
{"pmid": "21007696", "title": "A state program of eleemosynary care.", "content": "A state program of eleemosynary care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007696"}
{"pmid": "21007697", "title": "Analysis of neuropsychiatric rejectees from the state of Tennessee.", "content": "Analysis of neuropsychiatric rejectees from the state of Tennessee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007697"}
{"pmid": "21007699", "title": "Tuberculous meningitis.", "content": "Tuberculous meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007699"}
{"pmid": "21007698", "title": "Neurotic behavior patterns arising out of the combat situation.", "content": "Neurotic behavior patterns arising out of the combat situation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007698"}
{"pmid": "21007701", "title": "Ontogeny of bisexual differentiation in man.", "content": "Ontogeny of bisexual differentiation in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007701"}
{"pmid": "21007702", "title": "Unconscious processes in artistic creation.", "content": "Unconscious processes in artistic creation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007702"}
{"pmid": "21007700", "title": "The fear-allaying effect of pentothal sodium in electro-shock therapy.", "content": "The fear-allaying effect of pentothal sodium in electro-shock therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007700"}
{"pmid": "21007703", "title": "About the name and some pathologic functions of the unconscious.", "content": "About the name and some pathologic functions of the unconscious.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007703"}
{"pmid": "21007704", "title": "Oliver Cromwell and the Puritan Revolution.", "content": "Oliver Cromwell and the Puritan Revolution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007704"}
{"pmid": "21007705", "title": "Facts and figures on psychotherapy.", "content": "Facts and figures on psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007705"}
{"pmid": "21007706", "title": "Roentgenological studies of the gastrointestinal tract in psychosomatic conditions.", "content": "Roentgenological studies of the gastrointestinal tract in psychosomatic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007706"}
{"pmid": "21007707", "title": "A psychosomatic study of myself.", "content": "A psychosomatic study of myself.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007707"}
{"pmid": "21007708", "title": "The Woodworth Personal Data Sheet as applied to delinquents.", "content": "The Woodworth Personal Data Sheet as applied to delinquents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007708"}
{"pmid": "21007709", "title": "Motives of insomnia.", "content": "Motives of insomnia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007709"}
{"pmid": "21007710", "title": "Pituitary adenoma associated with chronic duodenal ulcer.", "content": "Pituitary adenoma associated with chronic duodenal ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007710"}
{"pmid": "21007711", "title": "Reflex differences in hypoglycemic schizophrenics with a few remarks on the possible role of the right hemisphere in the production of some mental symptoms.", "content": "Reflex differences in hypoglycemic schizophrenics with a few remarks on the possible role of the right hemisphere in the production of some mental symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007711"}
{"pmid": "21007712", "title": "The psychiatric evaluation of naval personnel returning from combat and overseas duty.", "content": "The psychiatric evaluation of naval personnel returning from combat and overseas duty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007712"}
{"pmid": "21007713", "title": "The significance of the depth of the physiologic cup of the optic disc for mental ability.", "content": "The significance of the depth of the physiologic cup of the optic disc for mental ability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007713"}
{"pmid": "21007715", "title": "The combat induced anxiety state as seen after return to duty.", "content": "The combat induced anxiety state as seen after return to duty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007715"}
{"pmid": "21007714", "title": "The diagnosis and classification of neurotic states; a reinterpretation of Eysenck's factors.", "content": "The diagnosis and classification of neurotic states; a reinterpretation of Eysenck's factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007714"}
{"pmid": "21007716", "title": "Aminoacetic acid (glycine) in the treatment of depression.", "content": "Aminoacetic acid (glycine) in the treatment of depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007716"}
{"pmid": "21007718", "title": "The natural history of sciatic neuritis.", "content": "The natural history of sciatic neuritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007718"}
{"pmid": "21007717", "title": "Electroencephalographic findings in psychopathic personalities.", "content": "Electroencephalographic findings in psychopathic personalities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007717"}
{"pmid": "21007719", "title": "Acute alterable states in multiple sclerosis.", "content": "Acute alterable states in multiple sclerosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007719"}
{"pmid": "21007720", "title": "Some reactions seens after electric shock treatment.", "content": "Some reactions seens after electric shock treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007720"}
{"pmid": "21007722", "title": "Extensive brain wounds; analysis of 159 cases occurring in a series of 342 penetrating war wounds of the brain.", "content": "Extensive brain wounds; analysis of 159 cases occurring in a series of 342 penetrating war wounds of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007722"}
{"pmid": "21007721", "title": "Transventricular wounds of the brain.", "content": "Transventricular wounds of the brain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007721"}
{"pmid": "21007723", "title": "Spasm of the internal carotid artery.", "content": "Spasm of the internal carotid artery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007723"}
{"pmid": "21007724", "title": "Neurogenic ossifying fibromyopathies; a preliminary report.", "content": "Neurogenic ossifying fibromyopathies; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007724"}
{"pmid": "21007725", "title": "Serous meningitis.", "content": "Serous meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007725"}
{"pmid": "21007726", "title": "Prevention of nerve regeneration and neuroma formation by caps of synthetic resin.", "content": "Prevention of nerve regeneration and neuroma formation by caps of synthetic resin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007726"}
{"pmid": "21007727", "title": "Early nerve and bone repair in war wounds.", "content": "Early nerve and bone repair in war wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007727"}
{"pmid": "21007728", "title": "The antigenicity of bovine thrombin; clinical evaluation.", "content": "The antigenicity of bovine thrombin; clinical evaluation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007728"}
{"pmid": "21007729", "title": "Extradural pneumatocele following tantalum cranioplasty.", "content": "Extradural pneumatocele following tantalum cranioplasty.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007729"}
{"pmid": "21007730", "title": "Clovis Vincent.", "content": "Clovis Vincent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007730"}
{"pmid": "21007731", "title": "Case reports and technical notes; anterior sacral meningocele.", "content": "Case reports and technical notes; anterior sacral meningocele.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007731"}
{"pmid": "21007733", "title": "Cysticercosis; a case report.", "content": "Cysticercosis; a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007733"}
{"pmid": "21007732", "title": "Fulminating gas gangrene of the brain; report of a case in a civilian.", "content": "Fulminating gas gangrene of the brain; report of a case in a civilian.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007732"}
{"pmid": "21007734", "title": "A new position for frontal craniotomy.", "content": "A new position for frontal craniotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007734"}
{"pmid": "21007735", "title": "Peripheral nerve lesion charts.", "content": "Peripheral nerve lesion charts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007735"}
{"pmid": "21007740", "title": "Anatomical study of traumatic disease of the spinal cord.", "content": "Anatomical study of traumatic disease of the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007740"}
{"pmid": "21007741", "title": "Lesions of the spine and spinal cord and the methods of their treatment (the early and late periods).", "content": "Lesions of the spine and spinal cord and the methods of their treatment (the early and late periods).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007741"}
{"pmid": "21007742", "title": "Sequelae of early surgical interference in gunshot wounds of the spine and spinal cord.", "content": "Sequelae of early surgical interference in gunshot wounds of the spine and spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007742"}
{"pmid": "21007743", "title": "Gunshot lesions of the spinal column and spinal cord.", "content": "Gunshot lesions of the spinal column and spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007743"}
{"pmid": "21007744", "title": "A study of the significance of disturbances of the function of the vegetative centres of the spinal cord in pathogenesis of complications of wounds of the spine and spinal cord.", "content": "A study of the significance of disturbances of the function of the vegetative centres of the spinal cord in pathogenesis of complications of wounds of the spine and spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007744"}
{"pmid": "21007745", "title": "Gunshot injuries of the cauda equina.", "content": "Gunshot injuries of the cauda equina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007745"}
{"pmid": "21007746", "title": "Suprapubic fistula in spinal traumae.", "content": "Suprapubic fistula in spinal traumae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007746"}
{"pmid": "21007747", "title": "Work of a spinal department of a front evacuo-hospital.", "content": "Work of a spinal department of a front evacuo-hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007747"}
{"pmid": "21007748", "title": "Chronaxia of the radices spinales in gunshot traumae of the spine and spinal cord.", "content": "Chronaxia of the radices spinales in gunshot traumae of the spine and spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007748"}
{"pmid": "21007749", "title": "Employment of rhythmical irritations as a new method of study in the diagnostics of traumae of the nervous system.", "content": "Employment of rhythmical irritations as a new method of study in the diagnostics of traumae of the nervous system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007749"}
{"pmid": "21007750", "title": "The sudden change of the lability of the neuro-muscular synapsis in operations on the spinal cord.", "content": "The sudden change of the lability of the neuro-muscular synapsis in operations on the spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007750"}
{"pmid": "21007751", "title": "The problem of the paralyzed bladder.", "content": "The problem of the paralyzed bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007751"}
{"pmid": "21007752", "title": "The care, maintenance and conservation of hospital equipment.", "content": "The care, maintenance and conservation of hospital equipment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007752"}
{"pmid": "21007753", "title": "Using the psychological approach.", "content": "Using the psychological approach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007753"}
{"pmid": "21007754", "title": "The industrial nurse and her approach to her job.", "content": "The industrial nurse and her approach to her job.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007754"}
{"pmid": "21007757", "title": "The anaemias.", "content": "The anaemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007757"}
{"pmid": "21007755", "title": "Personal adjustments in industrial nursing.", "content": "Personal adjustments in industrial nursing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007755"}
{"pmid": "21007756", "title": "The plant safety program; the nurse's influence.", "content": "The plant safety program; the nurse's influence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007756"}
{"pmid": "21007760", "title": "The management of abortion; description and causes.", "content": "The management of abortion; description and causes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007760"}
{"pmid": "21007759", "title": "Ideal house for the district nurse.", "content": "Ideal house for the district nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007759"}
{"pmid": "21007758", "title": "Septic thrombosis of the cavernous sinus followed by encephalitis.", "content": "Septic thrombosis of the cavernous sinus followed by encephalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007758"}
{"pmid": "21007761", "title": "Modern methods of controlling infection during the puerperium.", "content": "Modern methods of controlling infection during the puerperium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007761"}
{"pmid": "21007763", "title": "In a Japanese internment camp.", "content": "In a Japanese internment camp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007763"}
{"pmid": "21007762", "title": "The modern treatment of fractures.", "content": "The modern treatment of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007762"}
{"pmid": "21007764", "title": "The teaching of normal psychology to the student nurse.", "content": "The teaching of normal psychology to the student nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007764"}
{"pmid": "21007765", "title": "Modern means of controlling infection in the neo-natal and early infancy periods.", "content": "Modern means of controlling infection in the neo-natal and early infancy periods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007765"}
{"pmid": "21007766", "title": "Drugs for the cure of tuberculosis.", "content": "Drugs for the cure of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007766"}
{"pmid": "21007767", "title": "Epilepsy and the public health nurse.", "content": "Epilepsy and the public health nurse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007767"}
{"pmid": "21007768", "title": "An orthopedic service for the community.", "content": "An orthopedic service for the community.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007768"}
{"pmid": "21007771", "title": "Graduate training in ophthalmology.", "content": "Graduate training in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007771"}
{"pmid": "21007769", "title": "SUGGESTED school health policies; services for health protection and improvement.", "content": "SUGGESTED school health policies; services for health protection and improvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007769"}
{"pmid": "21007773", "title": "Eye conditions among children of premature, full-term, and hypermature birth.", "content": "Eye conditions among children of premature, full-term, and hypermature birth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007773"}
{"pmid": "21007770", "title": "Persistence and hyperplasia of the primary vitreous (tunica vasulosa lentis or retrolental fibroplasia).", "content": "Persistence and hyperplasia of the primary vitreous (tunica vasulosa lentis or retrolental fibroplasia).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007770"}
{"pmid": "21007772", "title": "Report from the Wilmer Institute on the results obtained in the treatment of myopia by visual training.", "content": "Report from the Wilmer Institute on the results obtained in the treatment of myopia by visual training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007772"}
{"pmid": "21007774", "title": "Vision in industry.", "content": "Vision in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007774"}
{"pmid": "21007775", "title": "A visual test for infants.", "content": "A visual test for infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007775"}
{"pmid": "21007776", "title": "Repeatability of keratometric readings.", "content": "Repeatability of keratometric readings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007776"}
{"pmid": "21007778", "title": "A tendon-transplantation technique for externalrectus paralysis.", "content": "A tendon-transplantation technique for externalrectus paralysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007778"}
{"pmid": "21007777", "title": "A case of multiple tuberculous nodules of the episclera.", "content": "A case of multiple tuberculous nodules of the episclera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007777"}
{"pmid": "21007780", "title": "Retinis circinata of unknown origin in a child.", "content": "Retinis circinata of unknown origin in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007780"}
{"pmid": "21007779", "title": "The Herbert iris-incarceration method of operation for glaucoma.", "content": "The Herbert iris-incarceration method of operation for glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007779"}
{"pmid": "21007782", "title": "Involvement of the ocular system in demyelinating diseases.", "content": "Involvement of the ocular system in demyelinating diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007782"}
{"pmid": "21007785", "title": "Keratitis sicca.", "content": "Keratitis sicca.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007785"}
{"pmid": "21007783", "title": "Sympathetic ophthalmitis following iridencleisis.", "content": "Sympathetic ophthalmitis following iridencleisis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007783"}
{"pmid": "21007786", "title": "Keratoconjunctivitis sicca.", "content": "Keratoconjunctivitis sicca.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007786"}
{"pmid": "21007787", "title": "Chronic blepharoconjunctivitis due to lid warts.", "content": "Chronic blepharoconjunctivitis due to lid warts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007787"}
{"pmid": "21007781", "title": "Syphilitic optic atrophy and tryparsamide amblyopia.", "content": "Syphilitic optic atrophy and tryparsamide amblyopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007781"}
{"pmid": "21007784", "title": "Cyclodiathermy.", "content": "Cyclodiathermy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007784"}
{"pmid": "21007788", "title": "The need for more basic courses in ophthalmology.", "content": "The need for more basic courses in ophthalmology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007788"}
{"pmid": "21007789", "title": "Refractive significance of Ortho-Rater tests.", "content": "Refractive significance of Ortho-Rater tests.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007789"}
{"pmid": "21007790", "title": "Visual education.", "content": "Visual education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007790"}
{"pmid": "21007791", "title": "Strabismus.", "content": "Strabismus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007791"}
{"pmid": "21007808", "title": "A versatile infra-red spectrograph.", "content": "A versatile infra-red spectrograph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007808"}
{"pmid": "21007810", "title": "An improved screening test for red-green color deficiency composed of available pseudo-isochromatic plates.", "content": "An improved screening test for red-green color deficiency composed of available pseudo-isochromatic plates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007810"}
{"pmid": "21007809", "title": "Alternating-current bolometer for infra-red spectroscopy.", "content": "Alternating-current bolometer for infra-red spectroscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007809"}
{"pmid": "21007811", "title": "Specification of railroad signal colors and glasses.", "content": "Specification of railroad signal colors and glasses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007811"}
{"pmid": "21007812", "title": "Transmittance and reflectance of germicidal energy.", "content": "Transmittance and reflectance of germicidal energy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007812"}
{"pmid": "21007813", "title": "Spectrophotometrical determinations of nucleic acids and nucleases in cerebrospinal fluids after cerebral concussion.", "content": "Spectrophotometrical determinations of nucleic acids and nucleases in cerebrospinal fluids after cerebral concussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007813"}
{"pmid": "21007814", "title": "Pharmacological responses of some previously x-rayed animals and plants.", "content": "Pharmacological responses of some previously x-rayed animals and plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007814"}
{"pmid": "21007815", "title": "Sunglasses and sunglass lenses.", "content": "Sunglasses and sunglass lenses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007815"}
{"pmid": "21007816", "title": "The referring of ocular pathology.", "content": "The referring of ocular pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007816"}
{"pmid": "21007817", "title": "Vision and the selection of personnel in industry.", "content": "Vision and the selection of personnel in industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007817"}
{"pmid": "21007818", "title": "Glaucoma and the prevention of blindness.", "content": "Glaucoma and the prevention of blindness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007818"}
{"pmid": "21007819", "title": "Medical social service with glaucoma patients.", "content": "Medical social service with glaucoma patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007819"}
{"pmid": "21007820", "title": "Glaucoma clinic procedures.", "content": "Glaucoma clinic procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007820"}
{"pmid": "21007821", "title": "Some impressions of oto-rhinolaryngology in Germany to-day.", "content": "Some impressions of oto-rhinolaryngology in Germany to-day.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007821"}
{"pmid": "21007822", "title": "Fenestration of the labyrinth.", "content": "Fenestration of the labyrinth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007822"}
{"pmid": "21007823", "title": "Case of left temporal lobe abscess, extradural abscess and lateral sinus thrombosis, following exacerbation of chronic suppurative otitis media, drainage, recovery.", "content": "Case of left temporal lobe abscess, extradural abscess and lateral sinus thrombosis, following exacerbation of chronic suppurative otitis media, drainage, recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007823"}
{"pmid": "21007824", "title": "Nutrition in ophthalmology and otolaryngology.", "content": "Nutrition in ophthalmology and otolaryngology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007824"}
{"pmid": "21007825", "title": "An improved method for classifying audiograms.", "content": "An improved method for classifying audiograms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007825"}
{"pmid": "21007826", "title": "Blast injuries of the ear.", "content": "Blast injuries of the ear.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007826"}
{"pmid": "21007836", "title": "An outline of the history of pediatrics in Sweden.", "content": "An outline of the history of pediatrics in Sweden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007836"}
{"pmid": "21007837", "title": "Social welfare of Swedish children, past and present.", "content": "Social welfare of Swedish children, past and present.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007837"}
{"pmid": "21007839", "title": "Primary tumours of the optic nerve and their relation to Recklinghausen's disease.", "content": "Primary tumours of the optic nerve and their relation to Recklinghausen's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007839"}
{"pmid": "21007838", "title": "The pediatric clinics of the universities and medical colleges as main centres of medical and medico-social pediatric care, research and instruction.", "content": "The pediatric clinics of the universities and medical colleges as main centres of medical and medico-social pediatric care, research and instruction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007838"}
{"pmid": "21007840", "title": "Roentgenologic determination of heart volume in infants.", "content": "Roentgenologic determination of heart volume in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007840"}
{"pmid": "21007841", "title": "On acute nicotine poisoning.", "content": "On acute nicotine poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007841"}
{"pmid": "21007842", "title": "Poliomyelitis and its prognosis in Sweden; condition and capacity for work after nine years' observation.", "content": "Poliomyelitis and its prognosis in Sweden; condition and capacity for work after nine years' observation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007842"}
{"pmid": "21007846", "title": "The treatment of morbus haemolyticus neonatorum (familial erythroblastosis foetalis); guiding lines for experiments towards an improvement.", "content": "The treatment of morbus haemolyticus neonatorum (familial erythroblastosis foetalis); guiding lines for experiments towards an improvement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007846"}
{"pmid": "21007844", "title": "The duration of physiological icterus neonatorum.", "content": "The duration of physiological icterus neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007844"}
{"pmid": "21007845", "title": "Sulfanilamide drugs and acute nephritis.", "content": "Sulfanilamide drugs and acute nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007845"}
{"pmid": "21007847", "title": "Experimentally produced gallop rhythm; a preliminary report.", "content": "Experimentally produced gallop rhythm; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007847"}
{"pmid": "21007848", "title": "Megacolon in the newborn; a clinical and röntgenological study with special regard to the pathogenesis; a preliminary report.", "content": "Megacolon in the newborn; a clinical and röntgenological study with special regard to the pathogenesis; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007848"}
{"pmid": "21007849", "title": "Treatment of pyloric stenosis in infants with methylscopolamine nitrate.", "content": "Treatment of pyloric stenosis in infants with methylscopolamine nitrate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007849"}
{"pmid": "21007850", "title": "The reaction of first-born children in infectious diseases.", "content": "The reaction of first-born children in infectious diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007850"}
{"pmid": "21007851", "title": "Acute rheumatic infection in children; clinical studies with special reference to the initial phase and the valuation of the cardiologic and hematologic signs.", "content": "Acute rheumatic infection in children; clinical studies with special reference to the initial phase and the valuation of the cardiologic and hematologic signs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007851"}
{"pmid": "21007853", "title": "Electro-encephalographic examinations of imbeciles; regarding the alpha frequency in spastics and mongoloid idiots.", "content": "Electro-encephalographic examinations of imbeciles; regarding the alpha frequency in spastics and mongoloid idiots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007853"}
{"pmid": "21007854", "title": "The present organization of school hygiene in Sweden.", "content": "The present organization of school hygiene in Sweden.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007854"}
{"pmid": "21007855", "title": "What is the cause of Harrison's groove in rickety infants?", "content": "What is the cause of Harrison's groove in rickety infants?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007855"}
{"pmid": "21007856", "title": "Instruction in social pediatrics.", "content": "Instruction in social pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007856"}
{"pmid": "21007857", "title": "The syndroma hypoglycemia-hydrops-erythroblastemia in new-born.", "content": "The syndroma hypoglycemia-hydrops-erythroblastemia in new-born.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007857"}
{"pmid": "21007859", "title": "Pernicious anaemia in children.", "content": "Pernicious anaemia in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007859"}
{"pmid": "21007858", "title": "Massive dose prophylaxis with vitamin D for prematurely born infants.", "content": "Massive dose prophylaxis with vitamin D for prematurely born infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007858"}
{"pmid": "21007860", "title": "Bacteriological examination of throat tests from children.", "content": "Bacteriological examination of throat tests from children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007860"}
{"pmid": "21007863", "title": "Chemo-prophylaxis against nosocomial infections.", "content": "Chemo-prophylaxis against nosocomial infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007863"}
{"pmid": "21007862", "title": "Moniliosis of the respiratory tract; bronchomoniliosis.", "content": "Moniliosis of the respiratory tract; bronchomoniliosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007862"}
{"pmid": "21007861", "title": "Three years' prophylaxis against rickets in prematures, with D2 massive dose.", "content": "Three years' prophylaxis against rickets in prematures, with D2 massive dose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007861"}
{"pmid": "21007864", "title": "Treatment of children's diabetes; ten years' experience without dietetic restrictions.", "content": "Treatment of children's diabetes; ten years' experience without dietetic restrictions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007864"}
{"pmid": "21007866", "title": "Some notes on the development of memory during the first years of life.", "content": "Some notes on the development of memory during the first years of life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007866"}
{"pmid": "21007868", "title": "Occurrence and significance of early periosteal proliferation in the diaphyses of premature infants.", "content": "Occurrence and significance of early periosteal proliferation in the diaphyses of premature infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007868"}
{"pmid": "21007869", "title": "Patent ductus arteriosus; diagnosis and indications for operation.", "content": "Patent ductus arteriosus; diagnosis and indications for operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007869"}
{"pmid": "21007870", "title": "On the relationship between prothrombin time and haematocrit value.", "content": "On the relationship between prothrombin time and haematocrit value.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007870"}
{"pmid": "21007871", "title": "Inflammatory processes in the central nervous system as a complication of scarlet fever.", "content": "Inflammatory processes in the central nervous system as a complication of scarlet fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007871"}
{"pmid": "21007872", "title": "On casein from human and cow's milk and their behaviour on hydrolysis with different proteolytic enzymes; preliminary report.", "content": "On casein from human and cow's milk and their behaviour on hydrolysis with different proteolytic enzymes; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007872"}
{"pmid": "21007873", "title": "The Stockholm centre for distribution of mothers' milk.", "content": "The Stockholm centre for distribution of mothers' milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007873"}
{"pmid": "21007874", "title": "The occurrence of erythema nodosum in children with primary tuberculosis, treated with sulfatiazol.", "content": "The occurrence of erythema nodosum in children with primary tuberculosis, treated with sulfatiazol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007874"}
{"pmid": "21007877", "title": "The relation between infantile tetany and rickets.", "content": "The relation between infantile tetany and rickets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007877"}
{"pmid": "21007878", "title": "Exanthema neonatorum from the allergic viewpoint, especially concerning the influence of orange and vitamin C supply to the mother.", "content": "Exanthema neonatorum from the allergic viewpoint, especially concerning the influence of orange and vitamin C supply to the mother.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007878"}
{"pmid": "21007879", "title": "Variations in the fat content of collected human milk.", "content": "Variations in the fat content of collected human milk.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007879"}
{"pmid": "21007880", "title": "Studies on the absorption of iron; absorption of iron from the stomach.", "content": "Studies on the absorption of iron; absorption of iron from the stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007880"}
{"pmid": "21007881", "title": "Breast-milk consumption of healthy full-term infants.", "content": "Breast-milk consumption of healthy full-term infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007881"}
{"pmid": "21007883", "title": "On shock in premature children; preliminary report.", "content": "On shock in premature children; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007883"}
{"pmid": "21007895", "title": "A typical hereditary ataxia.", "content": "A typical hereditary ataxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007895"}
{"pmid": "21007894", "title": "Little's disease; with report of a family.", "content": "Little's disease; with report of a family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007894"}
{"pmid": "21007897", "title": "The prevention of rheumatic recurrences in children by the use of sulfathiazole and sulfadiazine.", "content": "The prevention of rheumatic recurrences in children by the use of sulfathiazole and sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007897"}
{"pmid": "21007896", "title": "Penicillin treatment of pneumococcus meningitis in infants.", "content": "Penicillin treatment of pneumococcus meningitis in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007896"}
{"pmid": "21007898", "title": "Rickets: a study of calcium and phosphorus metabolism and of clinical findings as influenced by certain feedings.", "content": "Rickets: a study of calcium and phosphorus metabolism and of clinical findings as influenced by certain feedings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007898"}
{"pmid": "21007899", "title": "Proctological problems of the pediatrician.", "content": "Proctological problems of the pediatrician.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007899"}
{"pmid": "21007900", "title": "The heterophile antibody reaction in infants and children.", "content": "The heterophile antibody reaction in infants and children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007900"}
{"pmid": "21007901", "title": "Sedatives and stimulants in pediatric practice.", "content": "Sedatives and stimulants in pediatric practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007901"}
{"pmid": "21007902", "title": "Chorea in the Negro race.", "content": "Chorea in the Negro race.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007902"}
{"pmid": "21007903", "title": "Tracheotomy in bulbar poliomyelitis.", "content": "Tracheotomy in bulbar poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007903"}
{"pmid": "21007905", "title": "Meningitis caused by type F Hemophilus influenzae; report of a case with recovery.", "content": "Meningitis caused by type F Hemophilus influenzae; report of a case with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007905"}
{"pmid": "21007904", "title": "Cardiospasm in the newborn.", "content": "Cardiospasm in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007904"}
{"pmid": "21007906", "title": "The treatment with antiserum of acute laryngitis caused by Hemophilus influenzae.", "content": "The treatment with antiserum of acute laryngitis caused by Hemophilus influenzae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007906"}
{"pmid": "21007907", "title": "Meningococcic meningitis; a report of multiple cases occurring in the same family.", "content": "Meningococcic meningitis; a report of multiple cases occurring in the same family.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007907"}
{"pmid": "21007908", "title": "Cystic tuberculosis of the bone in a case of miliary tuberculosis.", "content": "Cystic tuberculosis of the bone in a case of miliary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007908"}
{"pmid": "21007909", "title": "Arachnodactyly; unusual complication following skull injury.", "content": "Arachnodactyly; unusual complication following skull injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007909"}
{"pmid": "21007910", "title": "The treatment of acute suppurative parotitis in infants.", "content": "The treatment of acute suppurative parotitis in infants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007910"}
{"pmid": "21007911", "title": "Hereditary skin defects in the newborn infant.", "content": "Hereditary skin defects in the newborn infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007911"}
{"pmid": "21007912", "title": "Generalized vaccinia and probable induced thiamine deficiency in a congenitally hypothyroid child.", "content": "Generalized vaccinia and probable induced thiamine deficiency in a congenitally hypothyroid child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007912"}
{"pmid": "21007913", "title": "The Greenberg modification of the Flagg laryngoscope; its use in asphyxia neonatorum.", "content": "The Greenberg modification of the Flagg laryngoscope; its use in asphyxia neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007913"}
{"pmid": "21007914", "title": "Communication on the Pepper Bill S.1318; a medical care credo; medical education.", "content": "Communication on the Pepper Bill S.1318; a medical care credo; medical education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007914"}
{"pmid": "21007917", "title": "The scope of pharmacy; an exhibit.", "content": "The scope of pharmacy; an exhibit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007917"}
{"pmid": "21007918", "title": "One: four vs two: three division of prepharmaceutic and pharmaceutic study.", "content": "One: four vs two: three division of prepharmaceutic and pharmaceutic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007918"}
{"pmid": "21007919", "title": "INFLUENZA virus vaccine, A and B.", "content": "INFLUENZA virus vaccine, A and B.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007919"}
{"pmid": "21007921", "title": "HIGHLIGHTS of 1945 achievements in pharmacy and related fields.", "content": "HIGHLIGHTS of 1945 achievements in pharmacy and related fields.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007921"}
{"pmid": "21007920", "title": "Aminoacid mixtures.", "content": "Aminoacid mixtures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007920"}
{"pmid": "21007922", "title": "Pharmacy of penicillin used by inhalation.", "content": "Pharmacy of penicillin used by inhalation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007922"}
{"pmid": "21007923", "title": "Continuous intravenous chemotherapy of Plasmodium lophurae infection in ducks.", "content": "Continuous intravenous chemotherapy of Plasmodium lophurae infection in ducks.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007923"}
{"pmid": "21007924", "title": "A short-term chronic toxicity test employing mice.", "content": "A short-term chronic toxicity test employing mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007924"}
{"pmid": "21007925", "title": "The central stimulant action of some basopressor amines.", "content": "The central stimulant action of some basopressor amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007925"}
{"pmid": "21007926", "title": "Observations on the nature of the antagonism of histamine by beta-dimethylaminoethyl benzhydryl ether (benadryl).", "content": "Observations on the nature of the antagonism of histamine by beta-dimethylaminoethyl benzhydryl ether (benadryl).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007926"}
{"pmid": "21007927", "title": "Antithyroid studies; the goitrogenic activity of certain chemotherapeutically active sulfones and related compounds.", "content": "Antithyroid studies; the goitrogenic activity of certain chemotherapeutically active sulfones and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007927"}
{"pmid": "21007928", "title": "Studies on the mechanism of action of sympathomimetic amines.", "content": "Studies on the mechanism of action of sympathomimetic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007928"}
{"pmid": "21007929", "title": "Studies on the mechanism of action of sympathomimetic amines; the effect of sympathomimetic amines on the succinoxidase system as influenced by the presence of alpha-tocopherol phosphate.", "content": "Studies on the mechanism of action of sympathomimetic amines; the effect of sympathomimetic amines on the succinoxidase system as influenced by the presence of alpha-tocopherol phosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007929"}
{"pmid": "21007930", "title": "Studies on shock induced by hemorrhage; isolation of a lactic dehydrogenase inhibitor from liver.", "content": "Studies on shock induced by hemorrhage; isolation of a lactic dehydrogenase inhibitor from liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007930"}
{"pmid": "21007931", "title": "Studies on shock induced by hemorrhage; the effects of injection into dogs of amino acid oxidase inhibitor.", "content": "Studies on shock induced by hemorrhage; the effects of injection into dogs of amino acid oxidase inhibitor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007931"}
{"pmid": "21007932", "title": "The effect of digitalis upon coagulation time of the blood.", "content": "The effect of digitalis upon coagulation time of the blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007932"}
{"pmid": "21007933", "title": "Studies on antimalarial drugs; the metabolism of quinine and quinidine in birds and mammals.", "content": "Studies on antimalarial drugs; the metabolism of quinine and quinidine in birds and mammals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007933"}
{"pmid": "21007934", "title": "The effect of different intravenous injection rates upon the AD50, LD50 and anesthetic duration of pentothal in mice, and strength-duration curves of depression.", "content": "The effect of different intravenous injection rates upon the AD50, LD50 and anesthetic duration of pentothal in mice, and strength-duration curves of depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007934"}
{"pmid": "21007935", "title": "The effect of ether, divinyl ether and cyclopropane anesthesia upon the heart rate and rhythm and blood pressure during normal respiratory activity and during artificial respiration after respiratory arrest.", "content": "The effect of ether, divinyl ether and cyclopropane anesthesia upon the heart rate and rhythm and blood pressure during normal respiratory activity and during artificial respiration after respiratory arrest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007935"}
{"pmid": "21007936", "title": "Studies on cyclopropane; the effect of premedication with demerol upon the heart rate, rhythm and blood pressure in dogs under cyclopropane anesthesia.", "content": "Studies on cyclopropane; the effect of premedication with demerol upon the heart rate, rhythm and blood pressure in dogs under cyclopropane anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007936"}
{"pmid": "21007937", "title": "The degradation of quinine in the duck, chicken and dog.", "content": "The degradation of quinine in the duck, chicken and dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007937"}
{"pmid": "21007938", "title": "The chronic toxicity of quinacrine (atabrine).", "content": "The chronic toxicity of quinacrine (atabrine).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007938"}
{"pmid": "21007939", "title": "The antidiuretic action of barbiturates (phenobarbital, amytal, pentobarbital) and the mechanism involved in this action.", "content": "The antidiuretic action of barbiturates (phenobarbital, amytal, pentobarbital) and the mechanism involved in this action.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007939"}
{"pmid": "21007940", "title": "The absorption of thiourea from ointments applied to wounds.", "content": "The absorption of thiourea from ointments applied to wounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007940"}
{"pmid": "21007941", "title": "Antibiotic substances active against M. tuberculosis.", "content": "Antibiotic substances active against M. tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007941"}
{"pmid": "21007942", "title": "Sulfonamides for bacillary dysentery; the antibacterial activity of sulfacarboxythiazoles and sulfathiadiazole.", "content": "Sulfonamides for bacillary dysentery; the antibacterial activity of sulfacarboxythiazoles and sulfathiadiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007942"}
{"pmid": "21007944", "title": "The spirocheticidal and trypanocidal action of acid-substituted phenyl arsenoxides as a function of pH and dissociation constants.", "content": "The spirocheticidal and trypanocidal action of acid-substituted phenyl arsenoxides as a function of pH and dissociation constants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007944"}
{"pmid": "21007943", "title": "The inhibitory effect of atabrine and some acridine derivatives upon acid-fast bacilli in vitro.", "content": "The inhibitory effect of atabrine and some acridine derivatives upon acid-fast bacilli in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007943"}
{"pmid": "21007945", "title": "The sympathomimetic vasodilating action of the aliphatic amines.", "content": "The sympathomimetic vasodilating action of the aliphatic amines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007945"}
{"pmid": "21007946", "title": "HYPERTENSION; its causes and treatment.", "content": "HYPERTENSION; its causes and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007946"}
{"pmid": "21007947", "title": "DYSMENORRHEA.", "content": "DYSMENORRHEA.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007947"}
{"pmid": "21007953", "title": "Military job evaluation: Army Air Forces.", "content": "Military job evaluation: Army Air Forces.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007953"}
{"pmid": "21007948", "title": "Studies on malarial parasites; the staining of two primate parasites by the Feulgen technique.", "content": "Studies on malarial parasites; the staining of two primate parasites by the Feulgen technique.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007948"}
{"pmid": "21007954", "title": "A statistical study of visual functions and industrial safety.", "content": "A statistical study of visual functions and industrial safety.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007954"}
{"pmid": "21007955", "title": "Effect of visual adaptation upon intensity of illumination preferred for reading with direct lighting.", "content": "Effect of visual adaptation upon intensity of illumination preferred for reading with direct lighting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007955"}
{"pmid": "21007950", "title": "Intensity effects of ultraviolet radiation of wavelength 2537 A on mitosis in the grasshopper neuroblast.", "content": "Intensity effects of ultraviolet radiation of wavelength 2537 A on mitosis in the grasshopper neuroblast.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007950"}
{"pmid": "21007949", "title": "Effects of ultraviolet irradiation on corneal epithelium; mitosis, nuclear fragmentation, post-traumatic cell movements, loss of tissue cohesion.", "content": "Effects of ultraviolet irradiation on corneal epithelium; mitosis, nuclear fragmentation, post-traumatic cell movements, loss of tissue cohesion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007949"}
{"pmid": "21007956", "title": "Mechanical aptitudes of university women.", "content": "Mechanical aptitudes of university women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007956"}
{"pmid": "21007957", "title": "Aptitude and interest patterns of art majors in a liberal arts college.", "content": "Aptitude and interest patterns of art majors in a liberal arts college.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007957"}
{"pmid": "21007959", "title": "Personality traits associated with abilities; with verbal and mathematical abilities.", "content": "Personality traits associated with abilities; with verbal and mathematical abilities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007959"}
{"pmid": "21007960", "title": "Rate of visual perception as a factor in rate of reading.", "content": "Rate of visual perception as a factor in rate of reading.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007960"}
{"pmid": "21007958", "title": "An empirical evaluation of study habits for college courses in French and Spanish.", "content": "An empirical evaluation of study habits for college courses in French and Spanish.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007958"}
{"pmid": "21007961", "title": "A comment on the correction of reliability coefficients for restriction of range.", "content": "A comment on the correction of reliability coefficients for restriction of range.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007961"}
{"pmid": "21007962", "title": "A study of the production of pleasant and unpleasant items as related to adolescent development.", "content": "A study of the production of pleasant and unpleasant items as related to adolescent development.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007962"}
{"pmid": "21007952", "title": "Note on the red luminescence and the red pigment of the railroad worm.", "content": "Note on the red luminescence and the red pigment of the railroad worm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007952"}
{"pmid": "21007963", "title": "Personality adjustments of children belonging to two minority groups.", "content": "Personality adjustments of children belonging to two minority groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007963"}
{"pmid": "21007951", "title": "Localization of adenylpyrophosphatase in cytoplasmic granules.", "content": "Localization of adenylpyrophosphatase in cytoplasmic granules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007951"}
{"pmid": "21007964", "title": "Relation of marks in college courses to the interestingness, value, and difficulty of the courses.", "content": "Relation of marks in college courses to the interestingness, value, and difficulty of the courses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007964"}
{"pmid": "21007965", "title": "An exploratory investigation of language by means of oscillographic and reaction time techniques.", "content": "An exploratory investigation of language by means of oscillographic and reaction time techniques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007965"}
{"pmid": "21007966", "title": "Fluctuation of sensation of liminal visual stimuli.", "content": "Fluctuation of sensation of liminal visual stimuli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007966"}
{"pmid": "21007967", "title": "Visual acuity and distance of observation.", "content": "Visual acuity and distance of observation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007967"}
{"pmid": "21007968", "title": "Primary and secondary suggestibility; an experimental and statistical study.", "content": "Primary and secondary suggestibility; an experimental and statistical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007968"}
{"pmid": "21007969", "title": "A repetition of the Blodgett experiment of latent learning.", "content": "A repetition of the Blodgett experiment of latent learning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007969"}
{"pmid": "21007970", "title": "The effects of attitudes on descriptions of pictures.", "content": "The effects of attitudes on descriptions of pictures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007970"}
{"pmid": "21007971", "title": "A psychological study of Stalin.", "content": "A psychological study of Stalin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007971"}
{"pmid": "21007972", "title": "Personal values and religious backgrounds.", "content": "Personal values and religious backgrounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007972"}
{"pmid": "21007973", "title": "The values of Negro women college students.", "content": "The values of Negro women college students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007973"}
{"pmid": "21007974", "title": "Studies in beauty; some determiners of the perception of beauty in women.", "content": "Studies in beauty; some determiners of the perception of beauty in women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007974"}
{"pmid": "21007975", "title": "The use of interviewer rapport as a method of detecting differences between public and private opinion.", "content": "The use of interviewer rapport as a method of detecting differences between public and private opinion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007975"}
{"pmid": "21007976", "title": "Cultural conflict and the feminine role; an experimental study.", "content": "Cultural conflict and the feminine role; an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007976"}
{"pmid": "21007977", "title": "A mutual validation of personality traits.", "content": "A mutual validation of personality traits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007977"}
{"pmid": "21007978", "title": "The essence of democracy.", "content": "The essence of democracy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007978"}
{"pmid": "21007979", "title": "Youth and progress.", "content": "Youth and progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007979"}
{"pmid": "21007980", "title": "Student attitudes toward religious practices.", "content": "Student attitudes toward religious practices.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007980"}
{"pmid": "21007981", "title": "CHARLES SPEARMAN, 1863-1945.", "content": "CHARLES SPEARMAN, 1863-1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007981"}
{"pmid": "21007983", "title": "A basis for analyzing test-retest reliability.", "content": "A basis for analyzing test-retest reliability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007983"}
{"pmid": "21007982", "title": "The prediction of choice.", "content": "The prediction of choice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007982"}
{"pmid": "21007984", "title": "A simple orthogonal multiple factor approximation procedure.", "content": "A simple orthogonal multiple factor approximation procedure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007984"}
{"pmid": "21007985", "title": "PROVINCIALISATION of public health services.", "content": "PROVINCIALISATION of public health services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007985"}
{"pmid": "21007988", "title": "The problem of malaria.", "content": "The problem of malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007988"}
{"pmid": "21007987", "title": "DEATH and disease in Bengal famine.", "content": "DEATH and disease in Bengal famine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007987"}
{"pmid": "21007986", "title": "Trends in under- and post-graduate teaching of public health and preventive medicine.", "content": "Trends in under- and post-graduate teaching of public health and preventive medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007986"}
{"pmid": "21007989", "title": "Some landmarks and lacunae in malariology in Bengal.", "content": "Some landmarks and lacunae in malariology in Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007989"}
{"pmid": "21007990", "title": "Food for the people.", "content": "Food for the people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007990"}
{"pmid": "21007991", "title": "Public health administration in Bengal.", "content": "Public health administration in Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007991"}
{"pmid": "21007992", "title": "Social hygiene work in Calcutta.", "content": "Social hygiene work in Calcutta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007992"}
{"pmid": "21007995", "title": "Planning for maternal and child health.", "content": "Planning for maternal and child health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007995"}
{"pmid": "21007993", "title": "School health service in Bengal.", "content": "School health service in Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007993"}
{"pmid": "21007994", "title": "Public health administration of Bengal.", "content": "Public health administration of Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007994"}
{"pmid": "21007997", "title": "The tuberculosis problem in Bengal.", "content": "The tuberculosis problem in Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007997"}
{"pmid": "21007996", "title": "Anti-malaria drainage for Bengal.", "content": "Anti-malaria drainage for Bengal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007996"}
{"pmid": "21007998", "title": "The fallacies as I see them.", "content": "The fallacies as I see them.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21007998"}
{"pmid": "21008007", "title": "HEALTH precautions for visitors to the tropics.", "content": "HEALTH precautions for visitors to the tropics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008007"}
{"pmid": "21008011", "title": "The courts cooperate in controlling venereal disease.", "content": "The courts cooperate in controlling venereal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008011"}
{"pmid": "21008012", "title": "Typhoid fever from clams.", "content": "Typhoid fever from clams.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008012"}
{"pmid": "21008013", "title": "An examination of the decline in non-pulmonary tuberculosis, and particularly abdominal tuberculosis, in the age group 15 years and upwards in London and rural districts of England and Wales and the South-Eastern counties between 1911 and 1938.", "content": "An examination of the decline in non-pulmonary tuberculosis, and particularly abdominal tuberculosis, in the age group 15 years and upwards in London and rural districts of England and Wales and the South-Eastern counties between 1911 and 1938.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008013"}
{"pmid": "21008014", "title": "Hostels for the aged.", "content": "Hostels for the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008014"}
{"pmid": "21008015", "title": "The death-rate of midwives.", "content": "The death-rate of midwives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008015"}
{"pmid": "21008016", "title": "FERTILITY and educational level of parents.", "content": "FERTILITY and educational level of parents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008016"}
{"pmid": "21008017", "title": "Fifty years of roentgen rays.", "content": "Fifty years of roentgen rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008017"}
{"pmid": "21008018", "title": "Pictures of organic molecules from x-ray diffraction data.", "content": "Pictures of organic molecules from x-ray diffraction data.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008018"}
{"pmid": "21008019", "title": "A million-volt chest radiograph.", "content": "A million-volt chest radiograph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008019"}
{"pmid": "21008020", "title": "Radiography of the pisiform bone.", "content": "Radiography of the pisiform bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008020"}
{"pmid": "21008021", "title": "An easily made serialograph.", "content": "An easily made serialograph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008021"}
{"pmid": "21008022", "title": "Infrared photography of patients.", "content": "Infrared photography of patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008022"}
{"pmid": "21008023", "title": "Extra-uterine pregnancy; a fetal skeleton.", "content": "Extra-uterine pregnancy; a fetal skeleton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008023"}
{"pmid": "21008024", "title": "Osteitis deformans with involvement of humerus.", "content": "Osteitis deformans with involvement of humerus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008024"}
{"pmid": "21008025", "title": "The teaching of radiology.", "content": "The teaching of radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008025"}
{"pmid": "21008026", "title": "The clinical significance of deformity of the cecum in amebiasis.", "content": "The clinical significance of deformity of the cecum in amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008026"}
{"pmid": "21008027", "title": "Roentgen findings in amebic disease of the liver.", "content": "Roentgen findings in amebic disease of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008027"}
{"pmid": "21008030", "title": "Roentgenologic visualization of the fractured temporal styloid process.", "content": "Roentgenologic visualization of the fractured temporal styloid process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008030"}
{"pmid": "21008028", "title": "An evaluation of automatic exposure control equipment in photofluorography.", "content": "An evaluation of automatic exposure control equipment in photofluorography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008028"}
{"pmid": "21008029", "title": "An unusual case of Ewing's sarcoma.", "content": "An unusual case of Ewing's sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008029"}
{"pmid": "21008031", "title": "Lipiodol intravasation during uterosalpingography with pulmonary complications.", "content": "Lipiodol intravasation during uterosalpingography with pulmonary complications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008031"}
{"pmid": "21008032", "title": "Bone rarefaction after skull injuries.", "content": "Bone rarefaction after skull injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008032"}
{"pmid": "21008033", "title": "The origin of cancer in man.", "content": "The origin of cancer in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008033"}
{"pmid": "21008034", "title": "DANGERS INHERENT in scattered cathode rays.", "content": "DANGERS INHERENT in scattered cathode rays.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008034"}
{"pmid": "21008046", "title": "A comparison of amphetamine sulfate with other stimulants of the central nervous system in morphine respiratory depression.", "content": "A comparison of amphetamine sulfate with other stimulants of the central nervous system in morphine respiratory depression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008046"}
{"pmid": "21008047", "title": "Hypobaric pontocaine; a new technic in spinal anaesthesia.", "content": "Hypobaric pontocaine; a new technic in spinal anaesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008047"}
{"pmid": "21008048", "title": "The utility of apomorphine in clinical anesthesia.", "content": "The utility of apomorphine in clinical anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008048"}
{"pmid": "21008049", "title": "Anesthesia in a maxillo-facial surgical unit with the British Liberation Army.", "content": "Anesthesia in a maxillo-facial surgical unit with the British Liberation Army.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008049"}
{"pmid": "21008050", "title": "Ether-air anesthesia; a technic.", "content": "Ether-air anesthesia; a technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008050"}
{"pmid": "21008051", "title": "Bilateral paralysis of the abducens and hypoglossal nerves following spinal anesthesia; case report.", "content": "Bilateral paralysis of the abducens and hypoglossal nerves following spinal anesthesia; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008051"}
{"pmid": "21008052", "title": "Acetaldehyde, a volatile anesthetic and sympathetic stimulant.", "content": "Acetaldehyde, a volatile anesthetic and sympathetic stimulant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008052"}
{"pmid": "21008053", "title": "Regional nerve block anesthesia.", "content": "Regional nerve block anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008053"}
{"pmid": "21008054", "title": "Elective early intubation.", "content": "Elective early intubation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008054"}
{"pmid": "21008055", "title": "Curare in adult tonsillectomy.", "content": "Curare in adult tonsillectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008055"}
{"pmid": "21008056", "title": "An endotracheal tube for babies.", "content": "An endotracheal tube for babies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008056"}
{"pmid": "21008057", "title": "Lesions of the spinal epidural space producing cord compression.", "content": "Lesions of the spinal epidural space producing cord compression.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008057"}
{"pmid": "21008058", "title": "Resection of the lung in the treatment of pulmonary tuberculosis.", "content": "Resection of the lung in the treatment of pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008058"}
{"pmid": "21008059", "title": "Studies on muscle atrophy; a method of recording power in situ and observations on effect of position of immobilization on atrophy of disuse and denervation.", "content": "Studies on muscle atrophy; a method of recording power in situ and observations on effect of position of immobilization on atrophy of disuse and denervation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008059"}
{"pmid": "21008060", "title": "Reestablishment of pancreatic secretion into the intestine after division of the pancreas; an experimental study.", "content": "Reestablishment of pancreatic secretion into the intestine after division of the pancreas; an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008060"}
{"pmid": "21008061", "title": "Intussusception of the vermiform appendix; report of a case.", "content": "Intussusception of the vermiform appendix; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008061"}
{"pmid": "21008062", "title": "Progress in orthopedic surgery for 1944; a review prepared by an editorial board of the American Academy of Orthopaedic Surgeons; diseases of growing and of adult bone.", "content": "Progress in orthopedic surgery for 1944; a review prepared by an editorial board of the American Academy of Orthopaedic Surgeons; diseases of growing and of adult bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008062"}
{"pmid": "21008063", "title": "Congenital deformities.", "content": "Congenital deformities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008063"}
{"pmid": "21008064", "title": "Tumors of bone and of synovial membrane.", "content": "Tumors of bone and of synovial membrane.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008064"}
{"pmid": "21008065", "title": "Conditions involving the hip joint.", "content": "Conditions involving the hip joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008065"}
{"pmid": "21008066", "title": "Conditions involving the foot and ankle.", "content": "Conditions involving the foot and ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008066"}
{"pmid": "21008067", "title": "Iliac-bone transplantation.", "content": "Iliac-bone transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008067"}
{"pmid": "21008068", "title": "The use of cancellous chips in bone-grafting.", "content": "The use of cancellous chips in bone-grafting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008068"}
{"pmid": "21008069", "title": "A method of treatment of chronic infective osteitis.", "content": "A method of treatment of chronic infective osteitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008069"}
{"pmid": "21008070", "title": "Pyogenic osteomyelitis of the spine.", "content": "Pyogenic osteomyelitis of the spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008070"}
{"pmid": "21008071", "title": "Osteochondromata of the pelvic bones.", "content": "Osteochondromata of the pelvic bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008071"}
{"pmid": "21008072", "title": "Late rupture of extensor policis longus tendon following Colles's fracture.", "content": "Late rupture of extensor policis longus tendon following Colles's fracture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008072"}
{"pmid": "21008073", "title": "Orthoroentgenography as a method of measuring the bones of the lower extremities.", "content": "Orthoroentgenography as a method of measuring the bones of the lower extremities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008073"}
{"pmid": "21008074", "title": "Ligaments of the knee joint; the relationship of the ligament of Humphry to the ligament of Wrisberg.", "content": "Ligaments of the knee joint; the relationship of the ligament of Humphry to the ligament of Wrisberg.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008074"}
{"pmid": "21008075", "title": "Treatment of fracture-dislocation of the interphalangeal joints of the hand.", "content": "Treatment of fracture-dislocation of the interphalangeal joints of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008075"}
{"pmid": "21008076", "title": "The position of the external hip joint in the above-the-knee prosthesis with pelvic suspension.", "content": "The position of the external hip joint in the above-the-knee prosthesis with pelvic suspension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008076"}
{"pmid": "21008077", "title": "Mutational dysostosis (cleidocranial dysostosis).", "content": "Mutational dysostosis (cleidocranial dysostosis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008077"}
{"pmid": "21008078", "title": "Arthrodesis of the hip produced by internal fixation.", "content": "Arthrodesis of the hip produced by internal fixation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008078"}
{"pmid": "21008079", "title": "Vertical traction in the early management of certain compound fractures of the femur.", "content": "Vertical traction in the early management of certain compound fractures of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008079"}
{"pmid": "21008080", "title": "Resection of the clavicle in vascular surgery.", "content": "Resection of the clavicle in vascular surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008080"}
{"pmid": "21008081", "title": "Transverse sacral folds.", "content": "Transverse sacral folds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008081"}
{"pmid": "21008082", "title": "Spastic flat-foot.", "content": "Spastic flat-foot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008082"}
{"pmid": "21008083", "title": "Bacteriological examination of the gastric contents in the diagnosis and management of tuberculosis of the bones and joints.", "content": "Bacteriological examination of the gastric contents in the diagnosis and management of tuberculosis of the bones and joints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008083"}
{"pmid": "21008084", "title": "Fracture of the medial epicondyle with displacement into the elbow-joint.", "content": "Fracture of the medial epicondyle with displacement into the elbow-joint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008084"}
{"pmid": "21008085", "title": "Contracture of the scalenus anterior, causing aneurysmal varix of right internal juglar vein, a case report.", "content": "Contracture of the scalenus anterior, causing aneurysmal varix of right internal juglar vein, a case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008085"}
{"pmid": "21008086", "title": "Survival of the head of the radius in a child after removal and replacement.", "content": "Survival of the head of the radius in a child after removal and replacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008086"}
{"pmid": "21008087", "title": "Severe pelvic fractures treated by fixed skeletal traction; report of a case.", "content": "Severe pelvic fractures treated by fixed skeletal traction; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008087"}
{"pmid": "21008088", "title": "Trichinosis as a cause of meralgia paraesthetica.", "content": "Trichinosis as a cause of meralgia paraesthetica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008088"}
{"pmid": "21008089", "title": "Localized coccidioidomycosis of bone.", "content": "Localized coccidioidomycosis of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008089"}
{"pmid": "21008090", "title": "Bilateral simultaneous dislocation of the shoulders.", "content": "Bilateral simultaneous dislocation of the shoulders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008090"}
{"pmid": "21008091", "title": "An appliance for the conservative treatment of acromioclavicular dislocation.", "content": "An appliance for the conservative treatment of acromioclavicular dislocation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008091"}
{"pmid": "21008092", "title": "Modification of Calot plaster jacket for immobilization of the cervical spine.", "content": "Modification of Calot plaster jacket for immobilization of the cervical spine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008092"}
{"pmid": "21008093", "title": "A universal splint for deformities of the hand.", "content": "A universal splint for deformities of the hand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008093"}
{"pmid": "21008094", "title": "An improved bone clamp and a plate for internal fixation of fractures.", "content": "An improved bone clamp and a plate for internal fixation of fractures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008094"}
{"pmid": "21008095", "title": "A simple traction device for the reduction of fractures of the forearm.", "content": "A simple traction device for the reduction of fractures of the forearm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008095"}
{"pmid": "21008096", "title": "A night splint for the correction of genu valgum.", "content": "A night splint for the correction of genu valgum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008096"}
{"pmid": "21008097", "title": "Glass cloth as a wound dressing.", "content": "Glass cloth as a wound dressing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008097"}
{"pmid": "21008098", "title": "Localized bone cyst of the os calcis.", "content": "Localized bone cyst of the os calcis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008098"}
{"pmid": "21008099", "title": "A simple retractor for spinal surgery.", "content": "A simple retractor for spinal surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008099"}
{"pmid": "21008100", "title": "Congenital dislocation of the hip.", "content": "Congenital dislocation of the hip.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008100"}
{"pmid": "21008101", "title": "Traumatic wet lung; observations on certain physiologic fundamentals of thoracic trauma.", "content": "Traumatic wet lung; observations on certain physiologic fundamentals of thoracic trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008101"}
{"pmid": "21008102", "title": "The use and control of thoracic surgical teams of an auxiliary surgical group.", "content": "The use and control of thoracic surgical teams of an auxiliary surgical group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008102"}
{"pmid": "21008103", "title": "Full-thickness flap closure of large thoracotomy due to chemical destruction of chest wall.", "content": "Full-thickness flap closure of large thoracotomy due to chemical destruction of chest wall.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008103"}
{"pmid": "21008104", "title": "Penicillin in pulmonary resection; preliminary report.", "content": "Penicillin in pulmonary resection; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008104"}
{"pmid": "21008105", "title": "Cylindroma of the bronchus; report of six cases.", "content": "Cylindroma of the bronchus; report of six cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008105"}
{"pmid": "21008106", "title": "Spontaneous pneumothoraces occurring in patients undergoing peroral endoscopy.", "content": "Spontaneous pneumothoraces occurring in patients undergoing peroral endoscopy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008106"}
{"pmid": "21008107", "title": "Experimental hemothorax.", "content": "Experimental hemothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008107"}
{"pmid": "21008108", "title": "Nerve block in the treatment of thoracic injuries.", "content": "Nerve block in the treatment of thoracic injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008108"}
{"pmid": "21008110", "title": "Aneurysm of the subclavian artery in an infant.", "content": "Aneurysm of the subclavian artery in an infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008110"}
{"pmid": "21008109", "title": "Recovery from hemolytic Staphylococcus aureus bactermia attributed to penicillin therapy; case report.", "content": "Recovery from hemolytic Staphylococcus aureus bactermia attributed to penicillin therapy; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008109"}
{"pmid": "21008113", "title": "Chronic sclerosing osteitis.", "content": "Chronic sclerosing osteitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008113"}
{"pmid": "21008114", "title": "The fibular bone graft in ununited fractures of the neck of the femur.", "content": "The fibular bone graft in ununited fractures of the neck of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008114"}
{"pmid": "21008115", "title": "Mortality after operation.", "content": "Mortality after operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008115"}
{"pmid": "21008116", "title": "Gastric adenomas; a pathologic study.", "content": "Gastric adenomas; a pathologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008116"}
{"pmid": "21008112", "title": "PREPARING sterile materials.", "content": "PREPARING sterile materials.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008112"}
{"pmid": "21008111", "title": "Ligature technic in tonsillectomies.", "content": "Ligature technic in tonsillectomies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008111"}
{"pmid": "21008117", "title": "Evaluation of posture based on structural and functional measurements.", "content": "Evaluation of posture based on structural and functional measurements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008117"}
{"pmid": "21008119", "title": "New and improved remedial exercise equipment, devised and improvised at Oliver General Hospital, Augusta, Ga.", "content": "New and improved remedial exercise equipment, devised and improvised at Oliver General Hospital, Augusta, Ga.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008119"}
{"pmid": "21008118", "title": "Ultraviolet radiation in the treatment of indolent, soft-tissue ulcerations.", "content": "Ultraviolet radiation in the treatment of indolent, soft-tissue ulcerations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008118"}
{"pmid": "21008135", "title": "Silicosis; a clinical study.", "content": "Silicosis; a clinical study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008135"}
{"pmid": "21008139", "title": "Tuberculosis in a tropical Naval hospital.", "content": "Tuberculosis in a tropical Naval hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008139"}
{"pmid": "21008137", "title": "Treatment of pulmonary tuberculosis with diasone.", "content": "Treatment of pulmonary tuberculosis with diasone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008137"}
{"pmid": "21008136", "title": "Poncet's disease; clinical observations on inflammatory and degenerative joint reactions in tuberculosis.", "content": "Poncet's disease; clinical observations on inflammatory and degenerative joint reactions in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008136"}
{"pmid": "21008138", "title": "Strict bed rest in pulmonary tuberculosis; an appraisal.", "content": "Strict bed rest in pulmonary tuberculosis; an appraisal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008138"}
{"pmid": "21008141", "title": "A suction cabinet for use in cavity aspiration (Monaldi).", "content": "A suction cabinet for use in cavity aspiration (Monaldi).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008141"}
{"pmid": "21008140", "title": "End results of artificial pneumothorax.", "content": "End results of artificial pneumothorax.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008140"}
{"pmid": "21008142", "title": "Anatomical studies on human tuberculosis; disseminated calcified small nodular hematogenous pulmonary tubercles, incidentally discovered.", "content": "Anatomical studies on human tuberculosis; disseminated calcified small nodular hematogenous pulmonary tubercles, incidentally discovered.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008142"}
{"pmid": "21008143", "title": "A comparison of the tuberculin patch test and the collodion-tuberculin test.", "content": "A comparison of the tuberculin patch test and the collodion-tuberculin test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008143"}
{"pmid": "21008144", "title": "A modified tuberculin patch test.", "content": "A modified tuberculin patch test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008144"}
{"pmid": "21008145", "title": "Clorox digestion; a comparison of clorox digestion and three other methods for finding acid-fast organisms in sputum.", "content": "Clorox digestion; a comparison of clorox digestion and three other methods for finding acid-fast organisms in sputum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008145"}
{"pmid": "21008146", "title": "Medicine as practiced during the 1840's.", "content": "Medicine as practiced during the 1840's.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008146"}
{"pmid": "21008147", "title": "Tuberculosis control in hospitals.", "content": "Tuberculosis control in hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008147"}
{"pmid": "21008148", "title": "Public health work in Korea.", "content": "Public health work in Korea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008148"}
{"pmid": "21008150", "title": "TUBERCULOSIS and parenthood.", "content": "TUBERCULOSIS and parenthood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008150"}
{"pmid": "21008149", "title": "Respiratory diseases.", "content": "Respiratory diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008149"}
{"pmid": "21008123", "title": "ELASTIC splint for foot drop.", "content": "ELASTIC splint for foot drop.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008123"}
{"pmid": "21008120", "title": "Psychological adjustments in activity therapy.", "content": "Psychological adjustments in activity therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008120"}
{"pmid": "21008122", "title": "MANAGEMENT of peripheral nerve injuries.", "content": "MANAGEMENT of peripheral nerve injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008122"}
{"pmid": "21008121", "title": "Early treatment of combined bone and nerve lesions.", "content": "Early treatment of combined bone and nerve lesions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008121"}
{"pmid": "21008151", "title": "[Phenomenon of hypoventilation of the pulmonary tissue in tuberculosis of the bronchial glands].", "content": "[Phenomenon of hypoventilation of the pulmonary tissue in tuberculosis of the bronchial glands].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008151"}
{"pmid": "21008152", "title": "[Ascorbic acid in experimental tuberculosis of guinea pigs].", "content": "[Ascorbic acid in experimental tuberculosis of guinea pigs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008152"}
{"pmid": "21008153", "title": "[On drip transfusion of blood in tuberculosis of the lungs].", "content": "[On drip transfusion of blood in tuberculosis of the lungs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008153"}
{"pmid": "21008155", "title": "[Electrosurgical treatment of lupus of the oral mucosa].", "content": "[Electrosurgical treatment of lupus of the oral mucosa].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008155"}
{"pmid": "21008154", "title": "[Experiment with employment of rubrocol in tuberculosis of the peripheral lymphatic glands in children and youths].", "content": "[Experiment with employment of rubrocol in tuberculosis of the peripheral lymphatic glands in children and youths].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008154"}
{"pmid": "21008161", "title": "Study of experimental urinary calculi; methods for producing and preventing calculous formation in the bladder and urethra of albino rats.", "content": "Study of experimental urinary calculi; methods for producing and preventing calculous formation in the bladder and urethra of albino rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008161"}
{"pmid": "21008162", "title": "Study of experimental urinary calculi; quantitative microchemical, spectrographic, and citric acid analyses of albino rat calculi, with a preliminary apatite report.", "content": "Study of experimental urinary calculi; quantitative microchemical, spectrographic, and citric acid analyses of albino rat calculi, with a preliminary apatite report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008162"}
{"pmid": "21008163", "title": "Renal calculi associated with hyperparathyroidism.", "content": "Renal calculi associated with hyperparathyroidism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008163"}
{"pmid": "21008164", "title": "The significance of spontaneous hematuria associated with hypertrophy of the prostate.", "content": "The significance of spontaneous hematuria associated with hypertrophy of the prostate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008164"}
{"pmid": "21008165", "title": "Bilateral orchiectomy in advanced or recurring carcinoma of the bladder with severe subjective symptoms; a preliminary report.", "content": "Bilateral orchiectomy in advanced or recurring carcinoma of the bladder with severe subjective symptoms; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008165"}
{"pmid": "21008166", "title": "Treatment of orchitis of mumps.", "content": "Treatment of orchitis of mumps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008166"}
{"pmid": "21008167", "title": "Repair of complete tear of the membranous urethra; case report and suggested new technique for operation.", "content": "Repair of complete tear of the membranous urethra; case report and suggested new technique for operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008167"}
{"pmid": "21008168", "title": "Reiter's syndrome.", "content": "Reiter's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008168"}
{"pmid": "21008169", "title": "A technique for the assay hyaluronidase in human semen and its correlation with the sperm concentration.", "content": "A technique for the assay hyaluronidase in human semen and its correlation with the sperm concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008169"}
{"pmid": "21008170", "title": "The transport of spermatozoa in the female reproductive tract.", "content": "The transport of spermatozoa in the female reproductive tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008170"}
{"pmid": "21008171", "title": "Report of U.S. Public Health Service Advisory Committee on public education for the prevention of venereal diseases, July 18, 1945.", "content": "Report of U.S. Public Health Service Advisory Committee on public education for the prevention of venereal diseases, July 18, 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008171"}
{"pmid": "21008172", "title": "Syphilis among civilians during World War II, January 1, 1942, through June 30, 1943.", "content": "Syphilis among civilians during World War II, January 1, 1942, through June 30, 1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008172"}
{"pmid": "21008173", "title": "The crossroads of veterinary and human medicine.", "content": "The crossroads of veterinary and human medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008173"}
{"pmid": "21008174", "title": "Further observations on canine Leptospirosis in Antigua, B.W.I.", "content": "Further observations on canine Leptospirosis in Antigua, B.W.I.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008174"}
{"pmid": "21008175", "title": "Observation on the incidence of the common stomach worm, Haemonchus contortus, in young cattle in a Montreal abattoir.", "content": "Observation on the incidence of the common stomach worm, Haemonchus contortus, in young cattle in a Montreal abattoir.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008175"}
{"pmid": "21008176", "title": "Observations on the permeability of the lactating bovine mammary gland to penicillin.", "content": "Observations on the permeability of the lactating bovine mammary gland to penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008176"}
{"pmid": "21008177", "title": "Studies in pullorum disease; transmission of infection to healthy birds by contact.", "content": "Studies in pullorum disease; transmission of infection to healthy birds by contact.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008177"}
{"pmid": "21008178", "title": "Veterinary work in Shanghai, China.", "content": "Veterinary work in Shanghai, China.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008178"}
{"pmid": "21008179", "title": "How may the incidence of tuberculosis in hogs be reduced.", "content": "How may the incidence of tuberculosis in hogs be reduced.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008179"}
{"pmid": "21008180", "title": "Additional outbreaks of equine encephalomyelitis in New Jersey pheasants.", "content": "Additional outbreaks of equine encephalomyelitis in New Jersey pheasants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008180"}
{"pmid": "21008181", "title": "Veterinary activities with animals at a port of embarkation.", "content": "Veterinary activities with animals at a port of embarkation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008181"}
{"pmid": "21008182", "title": "CASE of intersexuality (hermaphrodism) in a horned goat.", "content": "CASE of intersexuality (hermaphrodism) in a horned goat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008182"}
{"pmid": "21008183", "title": "Canine tuberculosis; a report of the first case officially diagnosed and confirmed in Puerto Rico.", "content": "Canine tuberculosis; a report of the first case officially diagnosed and confirmed in Puerto Rico.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008183"}
{"pmid": "21008184", "title": "Swine coccidiosis in Venezuela.", "content": "Swine coccidiosis in Venezuela.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008184"}
{"pmid": "21008185", "title": "LEISHMANIASIS (kala-azar) of dogs.", "content": "LEISHMANIASIS (kala-azar) of dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008185"}
{"pmid": "21008186", "title": "DDT; toxicity and indications.", "content": "DDT; toxicity and indications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008186"}
{"pmid": "21008187", "title": "INFECTIOUS pleuropneumonia of the goat.", "content": "INFECTIOUS pleuropneumonia of the goat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008187"}
{"pmid": "21008188", "title": "WORK of the Army veterinary services in relation to military dairy farms in India.", "content": "WORK of the Army veterinary services in relation to military dairy farms in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008188"}
{"pmid": "21008189", "title": "CASE of phosphorus burns in the dairy cow.", "content": "CASE of phosphorus burns in the dairy cow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008189"}
{"pmid": "21008190", "title": "Hydatid cysts in the horse.", "content": "Hydatid cysts in the horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008190"}
{"pmid": "21008191", "title": "No. 3 Veterinary Hospital and after.", "content": "No. 3 Veterinary Hospital and after.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008191"}
{"pmid": "21008192", "title": "An investigation into an outbreak of acute nephritis.", "content": "An investigation into an outbreak of acute nephritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008192"}
{"pmid": "21008193", "title": "Artificial breeding of dairy cattle as a practical procedure for the general practitioner.", "content": "Artificial breeding of dairy cattle as a practical procedure for the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008193"}
{"pmid": "21008194", "title": "On the etiology of abscesses in goats.", "content": "On the etiology of abscesses in goats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008194"}
{"pmid": "21008195", "title": "Teniacidal action of di-phenthane-70.", "content": "Teniacidal action of di-phenthane-70.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008195"}
{"pmid": "21008196", "title": "A method for studying numerical and topographic problems in the whole femoral marrow of rats and guinea pigs, with the use of undecalcified sections.", "content": "A method for studying numerical and topographic problems in the whole femoral marrow of rats and guinea pigs, with the use of undecalcified sections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008196"}
{"pmid": "21008197", "title": "The vital necessity of adrenal cortical tissue in a mammal and the effects of proliferation of cortical cells from dormant coelomic mesothelium.", "content": "The vital necessity of adrenal cortical tissue in a mammal and the effects of proliferation of cortical cells from dormant coelomic mesothelium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008197"}
{"pmid": "21008198", "title": "Mitotic division and degeneration of lymphocytes within the cells of intestinal epithelium in the mouse.", "content": "Mitotic division and degeneration of lymphocytes within the cells of intestinal epithelium in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008198"}
{"pmid": "21008199", "title": "A comparison of the action of extension of the knee and elbow joints in man.", "content": "A comparison of the action of extension of the knee and elbow joints in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008199"}
{"pmid": "21008200", "title": "Cross-sectional diameters and areas of the human spinal cord.", "content": "Cross-sectional diameters and areas of the human spinal cord.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008200"}
{"pmid": "21008201", "title": "The motion of the migrating cells in tissue cultures of lymph nodes.", "content": "The motion of the migrating cells in tissue cultures of lymph nodes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008201"}
{"pmid": "21008204", "title": "The nutritional requirements of the lactic acid bacteria and their application to biochemical research.", "content": "The nutritional requirements of the lactic acid bacteria and their application to biochemical research.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008204"}
{"pmid": "21008205", "title": "The interrelationship of iron and certain accessory factors in the growth of Rhizobium trifolii, strain 205.", "content": "The interrelationship of iron and certain accessory factors in the growth of Rhizobium trifolii, strain 205.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008205"}
{"pmid": "21008206", "title": "The pyrogenicity of bacterial contaminants found in biologic products.", "content": "The pyrogenicity of bacterial contaminants found in biologic products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008206"}
{"pmid": "21008207", "title": "Studies on the death of bacteria at low temperature; the influence of the intensity of the freezing temperature, repeated fluctuations of temperature, and the period of exposure to freezing temperatures on the mortality of Escherichia coli.", "content": "Studies on the death of bacteria at low temperature; the influence of the intensity of the freezing temperature, repeated fluctuations of temperature, and the period of exposure to freezing temperatures on the mortality of Escherichia coli.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008207"}
{"pmid": "21008208", "title": "Morphology and nature of the pleuropneumonia group of organisms.", "content": "Morphology and nature of the pleuropneumonia group of organisms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008208"}
{"pmid": "21008209", "title": "The paperdisc agar-plate method for the assay of antibiotic substances.", "content": "The paperdisc agar-plate method for the assay of antibiotic substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008209"}
{"pmid": "21008210", "title": "The influence of changes in concentration and temperature upon the bactericidal activity of formaldehyde in aqueous solutions.", "content": "The influence of changes in concentration and temperature upon the bactericidal activity of formaldehyde in aqueous solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008210"}
{"pmid": "21008211", "title": "The fermentation of glucose by certain gram-positive, nonsporeforming, anaerobic bacteria.", "content": "The fermentation of glucose by certain gram-positive, nonsporeforming, anaerobic bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008211"}
{"pmid": "21008212", "title": "Correlation between antibacterial power and chemical structure of higher alkyl ammonium ions.", "content": "Correlation between antibacterial power and chemical structure of higher alkyl ammonium ions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008212"}
{"pmid": "21008213", "title": "Entomology in malaria control.", "content": "Entomology in malaria control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008213"}
{"pmid": "21008214", "title": "Insect damage to nylon.", "content": "Insect damage to nylon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008214"}
{"pmid": "21008215", "title": "Some dinitrophenol derivatives as mosquito larvicides.", "content": "Some dinitrophenol derivatives as mosquito larvicides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008215"}
{"pmid": "21008216", "title": "The transport of insects in aircraft.", "content": "The transport of insects in aircraft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008216"}
{"pmid": "21008217", "title": "DDT compared with other insecticides for control of hemipterous insects on cotton.", "content": "DDT compared with other insecticides for control of hemipterous insects on cotton.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008217"}
{"pmid": "21008218", "title": "DDT for bollworn control during 1944.", "content": "DDT for bollworn control during 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008218"}
{"pmid": "21008219", "title": "DDT as a culicine larvicide.", "content": "DDT as a culicine larvicide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008219"}
{"pmid": "21008220", "title": "DDT dispersed from airplanes for control of adult mosquitoes.", "content": "DDT dispersed from airplanes for control of adult mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008220"}
{"pmid": "21008221", "title": "DDT-oil sprays applied from an airplane to control Anopheles and Mansonia mosquitoes.", "content": "DDT-oil sprays applied from an airplane to control Anopheles and Mansonia mosquitoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008221"}
{"pmid": "21008222", "title": "DDT surface sprays for control of stablefly breeding in shore deposits of marine grass.", "content": "DDT surface sprays for control of stablefly breeding in shore deposits of marine grass.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008222"}
{"pmid": "21008223", "title": "DDT to control ticks on vegetation.", "content": "DDT to control ticks on vegetation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008223"}
{"pmid": "21008224", "title": "DDT and rotenone used in oil to control the California red scale.", "content": "DDT and rotenone used in oil to control the California red scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008224"}
{"pmid": "21008225", "title": "DDT and other insecticides to control the Saratoga spittle insect on jack pine.", "content": "DDT and other insecticides to control the Saratoga spittle insect on jack pine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008225"}
{"pmid": "21008226", "title": "Laboratory studies with rotenone oil in sprays to control the California red scale.", "content": "Laboratory studies with rotenone oil in sprays to control the California red scale.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008226"}
{"pmid": "21008227", "title": "New insecticides for chicken lice control.", "content": "New insecticides for chicken lice control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008227"}
{"pmid": "21008228", "title": "Food preferences of the firebrat.", "content": "Food preferences of the firebrat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008228"}
{"pmid": "21008229", "title": "Insect pathology and biological control.", "content": "Insect pathology and biological control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008229"}
{"pmid": "21008231", "title": "Insecticides for control of the cotton flea hopper.", "content": "Insecticides for control of the cotton flea hopper.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008231"}
{"pmid": "21008230", "title": "The bloodsucking habits and growth of nymphs of Triatoma gerstaeckeri.", "content": "The bloodsucking habits and growth of nymphs of Triatoma gerstaeckeri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008230"}
{"pmid": "21008232", "title": "DDT for control of the grape bud beetle.", "content": "DDT for control of the grape bud beetle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008232"}
{"pmid": "21008234", "title": "Thanite as a control for ants.", "content": "Thanite as a control for ants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008234"}
{"pmid": "21008233", "title": "Control of housefly breeding in partly digested sewage sludge.", "content": "Control of housefly breeding in partly digested sewage sludge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008233"}
{"pmid": "21008235", "title": "Factors inducing diapause in the Oriental fruit moth.", "content": "Factors inducing diapause in the Oriental fruit moth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008235"}
{"pmid": "21008236", "title": "DDT and bedbugs in chicken houses.", "content": "DDT and bedbugs in chicken houses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008236"}
{"pmid": "21008237", "title": "The effect on the fingers of the poison of Formica exsectoides.", "content": "The effect on the fingers of the poison of Formica exsectoides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008237"}
{"pmid": "21008238", "title": "DDT residual spray tests in Panama.", "content": "DDT residual spray tests in Panama.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008238"}
{"pmid": "21008239", "title": "DDT and control of honeybees.", "content": "DDT and control of honeybees.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008239"}
{"pmid": "21008240", "title": "Methyl bromide for control of the pineapple mealybug.", "content": "Methyl bromide for control of the pineapple mealybug.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008240"}
{"pmid": "21008241", "title": "Dusting for cattle lice.", "content": "Dusting for cattle lice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008241"}
{"pmid": "21008242", "title": "DDT for the control of goat lice.", "content": "DDT for the control of goat lice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008242"}
{"pmid": "21008243", "title": "Mosquitoes of northwest Florida.", "content": "Mosquitoes of northwest Florida.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008243"}
{"pmid": "21008244", "title": "DDT for the tent caterpillar.", "content": "DDT for the tent caterpillar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008244"}
{"pmid": "21008245", "title": "Sorption of HCN by insect pupae.", "content": "Sorption of HCN by insect pupae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008245"}
{"pmid": "21008246", "title": "DDT-like effects from injection of other compounds into roaches.", "content": "DDT-like effects from injection of other compounds into roaches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008246"}
{"pmid": "21008247", "title": "Natural heteroagglutinins in the serum of the spiny lobster, Panulirus interruptus; chemical and antigenic relation to blood proteins.", "content": "Natural heteroagglutinins in the serum of the spiny lobster, Panulirus interruptus; chemical and antigenic relation to blood proteins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008247"}
{"pmid": "21008248", "title": "Studies on marine Bryozoa; Aeverrillia setigera (Hincks) 1887.", "content": "Studies on marine Bryozoa; Aeverrillia setigera (Hincks) 1887.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008248"}
{"pmid": "21008249", "title": "Studies on fresh-water Bryozoa; Fredericella australiensis var. browni, n. var.", "content": "Studies on fresh-water Bryozoa; Fredericella australiensis var. browni, n. var.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008249"}
{"pmid": "21008250", "title": "Studies on the biochemistry of tetrahymena; riboflavin, pantothen, biotin, niacin and pyridoxine in the growth of T. geleii W.", "content": "Studies on the biochemistry of tetrahymena; riboflavin, pantothen, biotin, niacin and pyridoxine in the growth of T. geleii W.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008250"}
{"pmid": "21008251", "title": "The structure of meiotic chromosomes in the grasshopper and its bearing on the nature of chromomeres and lamp-brush chromosomes.", "content": "The structure of meiotic chromosomes in the grasshopper and its bearing on the nature of chromomeres and lamp-brush chromosomes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008251"}
{"pmid": "21008252", "title": "[The sun, life and chlorophyll].", "content": "[The sun, life and chlorophyll].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008252"}
{"pmid": "21008253", "title": "[On the role of aminoacids in animal bodies].", "content": "[On the role of aminoacids in animal bodies].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008253"}
{"pmid": "21008255", "title": "[The present state of the problem of endocrine gland transplantation].", "content": "[The present state of the problem of endocrine gland transplantation].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008255"}
{"pmid": "21008254", "title": "[The blood and its substitutes].", "content": "[The blood and its substitutes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008254"}
{"pmid": "21008256", "title": "[Modern advances in pollinistics and the evolution of higher plants].", "content": "[Modern advances in pollinistics and the evolution of higher plants].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008256"}
{"pmid": "21008257", "title": "[Homotransplantation of the frog heart].", "content": "[Homotransplantation of the frog heart].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008257"}
{"pmid": "21008258", "title": "[Parthenogenetic females among certain races of the honey bee].", "content": "[Parthenogenetic females among certain races of the honey bee].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008258"}
{"pmid": "21008259", "title": "[The automatism and reflex in the activity of the respiratory centre of vertebrates].", "content": "[The automatism and reflex in the activity of the respiratory centre of vertebrates].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008259"}
{"pmid": "21008260", "title": "[The biochemistry of muscle training].", "content": "[The biochemistry of muscle training].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008260"}
{"pmid": "21008261", "title": "[Blood plasma proteins and their role in metabolic processes in the organism].", "content": "[Blood plasma proteins and their role in metabolic processes in the organism].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008261"}
{"pmid": "21008262", "title": "[New data concerning the nature of mammary gland malignant tumors].", "content": "[New data concerning the nature of mammary gland malignant tumors].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008262"}
{"pmid": "21008264", "title": "[Contribution to the history of the discovery by I.M. Setchenov of central inhibition].", "content": "[Contribution to the history of the discovery by I.M. Setchenov of central inhibition].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008264"}
{"pmid": "21008263", "title": "[Antagonistic substances and bacteria control in animals and plants].", "content": "[Antagonistic substances and bacteria control in animals and plants].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008263"}
{"pmid": "21008265", "title": "[The ecological coefficient as a new measure of the influence of external factors upon animals and men].", "content": "[The ecological coefficient as a new measure of the influence of external factors upon animals and men].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008265"}
{"pmid": "21008266", "title": "[On the interaction of genes and cytoplasm in development and heredity].", "content": "[On the interaction of genes and cytoplasm in development and heredity].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008266"}
{"pmid": "21008267", "title": "The carcinogenicity of p-dimethylaminoazobenzene in diets containing the fatty acids of hydrogenated coconut oil or of corn oil.", "content": "The carcinogenicity of p-dimethylaminoazobenzene in diets containing the fatty acids of hydrogenated coconut oil or of corn oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008267"}
{"pmid": "21008268", "title": "Certain effects of dietary fats on the production of liver tumors in rats fed p-dimethylaminoazobenzene.", "content": "Certain effects of dietary fats on the production of liver tumors in rats fed p-dimethylaminoazobenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008268"}
{"pmid": "21008269", "title": "Desoxyribonucleic acid in epidermal carcinogenesis induced by methylcholanthrene.", "content": "Desoxyribonucleic acid in epidermal carcinogenesis induced by methylcholanthrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008269"}
{"pmid": "21008270", "title": "Observations on experimentally produced sarcomas of pigeons.", "content": "Observations on experimentally produced sarcomas of pigeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008270"}
{"pmid": "21008271", "title": "Effects of ultraviolet radiation on 3,4-benzpyrene and other polycyclic aromatic hydrocarbons; absorption spectra and some chemical properties of the water-soluble products.", "content": "Effects of ultraviolet radiation on 3,4-benzpyrene and other polycyclic aromatic hydrocarbons; absorption spectra and some chemical properties of the water-soluble products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008271"}
{"pmid": "21008272", "title": "Effects of ultraviolet radiation on 3,4-benzpyrene and other polycyclic aromatic hydrocarbons; the role of benzene in the photoreactions in solutions containing it.", "content": "Effects of ultraviolet radiation on 3,4-benzpyrene and other polycyclic aromatic hydrocarbons; the role of benzene in the photoreactions in solutions containing it.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008272"}
{"pmid": "21008273", "title": "Effects of ultraviolet radiation on 3,4-benzpyrene and other polycyclic aromatic hydrocarbons; carcinogenic activity of aqueous extracts from irradiated 3,4-benzpyrene.", "content": "Effects of ultraviolet radiation on 3,4-benzpyrene and other polycyclic aromatic hydrocarbons; carcinogenic activity of aqueous extracts from irradiated 3,4-benzpyrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008273"}
{"pmid": "21008274", "title": "The effect of smoking cigarettes on the peripheral blood flow in subjects in the older age group with coronary arteriosclerosis and hypertension.", "content": "The effect of smoking cigarettes on the peripheral blood flow in subjects in the older age group with coronary arteriosclerosis and hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008274"}
{"pmid": "21008275", "title": "Electrocardiographic changes in early syphilis prior to and upon completion of intensive arsenotherapy.", "content": "Electrocardiographic changes in early syphilis prior to and upon completion of intensive arsenotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008275"}
{"pmid": "21008276", "title": "Studies concerning the etiology and pathogenesis of neurocirculatory asthenia; the respiratory manifestations of neurocirculatory asthenia.", "content": "Studies concerning the etiology and pathogenesis of neurocirculatory asthenia; the respiratory manifestations of neurocirculatory asthenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008276"}
{"pmid": "21008277", "title": "Cardiac aneurysm with spontaneous rupture; report of two cases.", "content": "Cardiac aneurysm with spontaneous rupture; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008277"}
{"pmid": "21008278", "title": "The relative incidence of rheumatic valve disease in New York and Costa Rica and its bearing on the rheumatic origin of calcareous aortic stenosis.", "content": "The relative incidence of rheumatic valve disease in New York and Costa Rica and its bearing on the rheumatic origin of calcareous aortic stenosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008278"}
{"pmid": "21008279", "title": "The electrocardiogram in pneumoperitoneum.", "content": "The electrocardiogram in pneumoperitoneum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008279"}
{"pmid": "21008280", "title": "The relation of age and other factors to cardiac subendothelial hemorrhage in dogs.", "content": "The relation of age and other factors to cardiac subendothelial hemorrhage in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008280"}
{"pmid": "21008281", "title": "Angina pectoris with particular reference to its occurrence before and after myocardial infarction.", "content": "Angina pectoris with particular reference to its occurrence before and after myocardial infarction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008281"}
{"pmid": "21008282", "title": "Facts and fallacies about the normal apex beat.", "content": "Facts and fallacies about the normal apex beat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008282"}
{"pmid": "21008283", "title": "Periarteritis nodosa; report of case.", "content": "Periarteritis nodosa; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008283"}
{"pmid": "21008284", "title": "Complete A-V block in a fetus, case report.", "content": "Complete A-V block in a fetus, case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008284"}
{"pmid": "21008285", "title": "Annulus fibrosus calcification of the mitral valve.", "content": "Annulus fibrosus calcification of the mitral valve.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008285"}
{"pmid": "21008286", "title": "Contusion of the heart.", "content": "Contusion of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008286"}
{"pmid": "21008287", "title": "Mercurial diuretics; intolerance as shown by skin sensitivity.", "content": "Mercurial diuretics; intolerance as shown by skin sensitivity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008287"}
{"pmid": "21008288", "title": "The effect of emetine on the heart.", "content": "The effect of emetine on the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008288"}
{"pmid": "21008289", "title": "The carotid shudder.", "content": "The carotid shudder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008289"}
{"pmid": "21008290", "title": "A quantitative electrocardiographic method.", "content": "A quantitative electrocardiographic method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008290"}
{"pmid": "21008291", "title": "A case of myxoma of the heart.", "content": "A case of myxoma of the heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008291"}
{"pmid": "21008292", "title": "Paroxyamal tachycardia and 2:1 heart block.", "content": "Paroxyamal tachycardia and 2:1 heart block.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008292"}
{"pmid": "21008294", "title": "Experimental auricular fibrillation.", "content": "Experimental auricular fibrillation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008294"}
{"pmid": "21008293", "title": "Immersion as a factor in the development of hypertension.", "content": "Immersion as a factor in the development of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008293"}
{"pmid": "21008295", "title": "Disease of the pericardium.", "content": "Disease of the pericardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008295"}
{"pmid": "21008296", "title": "Rheumatic disease of the pericardium.", "content": "Rheumatic disease of the pericardium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008296"}
{"pmid": "21008297", "title": "The electrocardiogram of pericardial disease.", "content": "The electrocardiogram of pericardial disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008297"}
{"pmid": "21008298", "title": "Human biotin metabolism on various levels of biotin intake.", "content": "Human biotin metabolism on various levels of biotin intake.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008298"}
{"pmid": "21008299", "title": "Liver arginase; preparation of extracts of high potency, chemical properties, activation-inhibitation, and pH-activity.", "content": "Liver arginase; preparation of extracts of high potency, chemical properties, activation-inhibitation, and pH-activity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008299"}
{"pmid": "21008300", "title": "Liver arginase; kinetic properties.", "content": "Liver arginase; kinetic properties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008300"}
{"pmid": "21008301", "title": "Penicillin; penicillinase.", "content": "Penicillin; penicillinase.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008301"}
{"pmid": "21008302", "title": "The activation of papain and related plant enzymes with sodium thiosulfate.", "content": "The activation of papain and related plant enzymes with sodium thiosulfate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008302"}
{"pmid": "21008303", "title": "The effect of tocopherol and of fat on the resistance of rats to anoxic anoxia.", "content": "The effect of tocopherol and of fat on the resistance of rats to anoxic anoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008303"}
{"pmid": "21008304", "title": "Factors influencing the destructive effects of acidic beverages on the teeth of white rats and hamsters.", "content": "Factors influencing the destructive effects of acidic beverages on the teeth of white rats and hamsters.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008304"}
{"pmid": "21008305", "title": "Preparation of the egg yolk lipoprotein, lipovitellin.", "content": "Preparation of the egg yolk lipoprotein, lipovitellin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008305"}
{"pmid": "21008306", "title": "Estimation of blood in tissue.", "content": "Estimation of blood in tissue.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008306"}
{"pmid": "21008307", "title": "The occurrence and estimation of phytofluene in plants.", "content": "The occurrence and estimation of phytofluene in plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008307"}
{"pmid": "21008308", "title": "Granulocytopenia and anemia in riboflavin-deficient rats and treatment with L. casei factor (folic acid) and riboflavin.", "content": "Granulocytopenia and anemia in riboflavin-deficient rats and treatment with L. casei factor (folic acid) and riboflavin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008308"}
{"pmid": "21008309", "title": "The inactivation of iron by 2,2'-bipyridine and its effect on riboflavin synthesis by Clostridium acetobutylicum.", "content": "The inactivation of iron by 2,2'-bipyridine and its effect on riboflavin synthesis by Clostridium acetobutylicum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008309"}
{"pmid": "21008310", "title": "Infection by viruses.", "content": "Infection by viruses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008310"}
{"pmid": "21008311", "title": "Centrifugation.", "content": "Centrifugation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008311"}
{"pmid": "21008312", "title": "Molecular distillation.", "content": "Molecular distillation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008312"}
{"pmid": "21008313", "title": "Modifying the viscosity of sulfur.", "content": "Modifying the viscosity of sulfur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008313"}
{"pmid": "21008314", "title": "Kinetics of sucrose crystallization; sucrose/nonsucrose solutions.", "content": "Kinetics of sucrose crystallization; sucrose/nonsucrose solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008314"}
{"pmid": "21008315", "title": "Vitamin retention in processed meat; effect of storage.", "content": "Vitamin retention in processed meat; effect of storage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008315"}
{"pmid": "21008316", "title": "Nitrogenous constituents of flaxseed; peptization.", "content": "Nitrogenous constituents of flaxseed; peptization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008316"}
{"pmid": "21008317", "title": "Storage of dried fruit; influence of moisture and sulfur dioxide on deterioration of apricots.", "content": "Storage of dried fruit; influence of moisture and sulfur dioxide on deterioration of apricots.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008317"}
{"pmid": "21008318", "title": "Physical, chemical and immunological properties of phosphorylated crystalline horse serum albumin.", "content": "Physical, chemical and immunological properties of phosphorylated crystalline horse serum albumin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008318"}
{"pmid": "21008319", "title": "Proportion of ester anion and amide from esters and sodium amide; carbonation of esters; synthesis of malonic acid derivatives.", "content": "Proportion of ester anion and amide from esters and sodium amide; carbonation of esters; synthesis of malonic acid derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008319"}
{"pmid": "21008320", "title": "Streptomyces antibiotics; hydrolytic cleavage of streptomycin to streptidine.", "content": "Streptomyces antibiotics; hydrolytic cleavage of streptomycin to streptidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008320"}
{"pmid": "21008321", "title": "Derivatives of 6-methoxy-8-aminoquinoline.", "content": "Derivatives of 6-methoxy-8-aminoquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008321"}
{"pmid": "21008323", "title": "The polymorphism of sulfapyridine.", "content": "The polymorphism of sulfapyridine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008323"}
{"pmid": "21008322", "title": "Reaction of formaldehyde with proteins; participation of the guanidyl groups and evidence of crosslinking.", "content": "Reaction of formaldehyde with proteins; participation of the guanidyl groups and evidence of crosslinking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008322"}
{"pmid": "21008324", "title": "Studies in chemotherapy; some sulfanilamidoheterocycles.", "content": "Studies in chemotherapy; some sulfanilamidoheterocycles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008324"}
{"pmid": "21008325", "title": "Synthesis of antimalarials; the synthesis of certain compounds related to quinacrine.", "content": "Synthesis of antimalarials; the synthesis of certain compounds related to quinacrine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008325"}
{"pmid": "21008327", "title": "Some 7-substituted 4-aminoquinoline derivatives.", "content": "Some 7-substituted 4-aminoquinoline derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008327"}
{"pmid": "21008328", "title": "The condensation of pyruvic acid and formamide.", "content": "The condensation of pyruvic acid and formamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008328"}
{"pmid": "21008326", "title": "The splitting of human gamma globulin antibodies by papain and bromelin.", "content": "The splitting of human gamma globulin antibodies by papain and bromelin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008326"}
{"pmid": "21008329", "title": "The role of neighboring groups in replacement reactions; the reaction of stilbene dichlorides with silver acetate.", "content": "The role of neighboring groups in replacement reactions; the reaction of stilbene dichlorides with silver acetate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008329"}
{"pmid": "21008333", "title": "Bromine analogs of DDT.", "content": "Bromine analogs of DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008333"}
{"pmid": "21008330", "title": "QUINOLINES; the synthesis of 3-methyl-4-(1'methyl-4'-diethylaminobutylamino)-quinoline and some 6-substituted derivatives.", "content": "QUINOLINES; the synthesis of 3-methyl-4-(1'methyl-4'-diethylaminobutylamino)-quinoline and some 6-substituted derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008330"}
{"pmid": "21008334", "title": "Observations on the equilibrium between cis- and transstilbene.", "content": "Observations on the equilibrium between cis- and transstilbene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008334"}
{"pmid": "21008331", "title": "Quinolines; the synthesis of 8-substituted 3-methyl-4-(1'-methyl-4'-diethylaminobutylamino)-quinolines.", "content": "Quinolines; the synthesis of 8-substituted 3-methyl-4-(1'-methyl-4'-diethylaminobutylamino)-quinolines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008331"}
{"pmid": "21008337", "title": "A dimorphic form of d-catechin.", "content": "A dimorphic form of d-catechin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008337"}
{"pmid": "21008335", "title": "Stability of DDT and related compounds.", "content": "Stability of DDT and related compounds.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008335"}
{"pmid": "21008336", "title": "The synthesis of d1-methionine.", "content": "The synthesis of d1-methionine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008336"}
{"pmid": "21008332", "title": "A study of the behavior of dextrose sodium chloride in hydrochloric acid solutions.", "content": "A study of the behavior of dextrose sodium chloride in hydrochloric acid solutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008332"}
{"pmid": "21008338", "title": "6'-methoxy-8-oximino-3-propyl-rubatoxanone.", "content": "6'-methoxy-8-oximino-3-propyl-rubatoxanone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008338"}
{"pmid": "21008339", "title": "A new synthesis of 7,8-diaminoquinoline.", "content": "A new synthesis of 7,8-diaminoquinoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008339"}
{"pmid": "21008340", "title": "Penicillin yields from new mold strains.", "content": "Penicillin yields from new mold strains.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008340"}
{"pmid": "21008342", "title": "Sulphonamides; the action of amines on ethyl 4-sulphanilamidobenzoate; some alternative preparative methods for sulphanilamidobenzamides.", "content": "Sulphonamides; the action of amines on ethyl 4-sulphanilamidobenzoate; some alternative preparative methods for sulphanilamidobenzamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008342"}
{"pmid": "21008341", "title": "Sulphonamides; the action of ammonia on sulphanilamidobenzoic esters in the light of the general theory of ester ammonolysis.", "content": "Sulphonamides; the action of ammonia on sulphanilamidobenzoic esters in the light of the general theory of ester ammonolysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008341"}
{"pmid": "21008343", "title": "The quantitative estimation of xylose.", "content": "The quantitative estimation of xylose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008343"}
{"pmid": "21008344", "title": "The chemistry of gum tragacanth; tragacanthic acid.", "content": "The chemistry of gum tragacanth; tragacanthic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008344"}
{"pmid": "21008345", "title": "The chemistry of gum tragacanth; derivatives of d- and l-fucose.", "content": "The chemistry of gum tragacanth; derivatives of d- and l-fucose.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008345"}
{"pmid": "21008346", "title": "Absorption spectra of acridines; the hydroxyacridines.", "content": "Absorption spectra of acridines; the hydroxyacridines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008346"}
{"pmid": "21008347", "title": "Studies in the detoxication of catalyst poisons; the detoxication of cystein with metallic per-acids.", "content": "Studies in the detoxication of catalyst poisons; the detoxication of cystein with metallic per-acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008347"}
{"pmid": "21008348", "title": "Contributions to the chemistry of synthetic antimalarials; some delta-diethylamino-alpha-methylbutylamino derivatives of pyridine and thiazole.", "content": "Contributions to the chemistry of synthetic antimalarials; some delta-diethylamino-alpha-methylbutylamino derivatives of pyridine and thiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008348"}
{"pmid": "21008349", "title": "The capsular polysaccharide of rhizobium radicicolum.", "content": "The capsular polysaccharide of rhizobium radicicolum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008349"}
{"pmid": "21008350", "title": "The interconversion of iron oxides and sulphides.", "content": "The interconversion of iron oxides and sulphides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008350"}
{"pmid": "21008351", "title": "New potential chemotherapeutic agents; derivatives of aminoquinoxalines.", "content": "New potential chemotherapeutic agents; derivatives of aminoquinoxalines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008351"}
{"pmid": "21008352", "title": "A preliminary study of the polyuronide hemicellulose of Phormium tenax (N.Z.flax).", "content": "A preliminary study of the polyuronide hemicellulose of Phormium tenax (N.Z.flax).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008352"}
{"pmid": "21008354", "title": "Some derivatives of 1:1:1-trichloro-2: 2-di (4-chlorophenyl) ethane (DDT).", "content": "Some derivatives of 1:1:1-trichloro-2: 2-di (4-chlorophenyl) ethane (DDT).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008354"}
{"pmid": "21008353", "title": "Structure of compounds of ferrocyanide type; crystal structure of hexamethylisocyanidoferrous chloride.", "content": "Structure of compounds of ferrocyanide type; crystal structure of hexamethylisocyanidoferrous chloride.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008353"}
{"pmid": "21008355", "title": "Mesohydric tautomerism.", "content": "Mesohydric tautomerism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008355"}
{"pmid": "21008357", "title": "New potential chemotherapeutic agents; derivatives of 2-amino-benzocinnoline.", "content": "New potential chemotherapeutic agents; derivatives of 2-amino-benzocinnoline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008357"}
{"pmid": "21008356", "title": "The action of methanol on phenol in the presence of alumina; formation of anisole, methylated phenols, and hexamethylbenzene.", "content": "The action of methanol on phenol in the presence of alumina; formation of anisole, methylated phenols, and hexamethylbenzene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008356"}
{"pmid": "21008358", "title": "Synthesis of diamino sulphones.", "content": "Synthesis of diamino sulphones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008358"}
{"pmid": "21008359", "title": "Derivatives of l-azanthraquinone.", "content": "Derivatives of l-azanthraquinone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008359"}
{"pmid": "21008362", "title": "A review of the clinical and roentgenologic manifestations of incipient periodontal disease.", "content": "A review of the clinical and roentgenologic manifestations of incipient periodontal disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008362"}
{"pmid": "21008360", "title": "The union of gaseous oxygen with methyl oleate, linoleate, and linolenate.", "content": "The union of gaseous oxygen with methyl oleate, linoleate, and linolenate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008360"}
{"pmid": "21008361", "title": "The preparation of some 2:3-naphthalene derivatives.", "content": "The preparation of some 2:3-naphthalene derivatives.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008361"}
{"pmid": "21008363", "title": "Local acidity; a cause of dental erosion-abrasion; progress report of the Erosion-Abrasion Committee of the New York Academy of Dentistry.", "content": "Local acidity; a cause of dental erosion-abrasion; progress report of the Erosion-Abrasion Committee of the New York Academy of Dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008363"}
{"pmid": "21008364", "title": "Numbness of lips, tongue and face.", "content": "Numbness of lips, tongue and face.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008364"}
{"pmid": "21008365", "title": "Thrush (monilia albicans).", "content": "Thrush (monilia albicans).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008365"}
{"pmid": "21008366", "title": "Autonomy in dental education.", "content": "Autonomy in dental education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008366"}
{"pmid": "21008368", "title": "PROPOSAL to convert the School of Dental and Oral Surgery into a Department of Dentistry of the Medical School.", "content": "PROPOSAL to convert the School of Dental and Oral Surgery into a Department of Dentistry of the Medical School.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008368"}
{"pmid": "21008367", "title": "The plan of Columbia University, aimed to improve the training of dentists.", "content": "The plan of Columbia University, aimed to improve the training of dentists.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008367"}
{"pmid": "21008370", "title": "Advance in the construction and use of splints in the treatment of fractures of the jaws.", "content": "Advance in the construction and use of splints in the treatment of fractures of the jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008370"}
{"pmid": "21008371", "title": "The spring bridge.", "content": "The spring bridge.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008371"}
{"pmid": "21008369", "title": "Acceleration of the setting of zinc oxide cements.", "content": "Acceleration of the setting of zinc oxide cements.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008369"}
{"pmid": "21008373", "title": "Restoration of fractured incisors in children.", "content": "Restoration of fractured incisors in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008373"}
{"pmid": "21008372", "title": "A case of cerebral anoxaemia occurring as the result of anoxia during the administration of sodium pentothal.", "content": "A case of cerebral anoxaemia occurring as the result of anoxia during the administration of sodium pentothal.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008372"}
{"pmid": "21008374", "title": "Surgery of the torus palatinus.", "content": "Surgery of the torus palatinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008374"}
{"pmid": "21008376", "title": "The conservative treatment of hypertrophic gingivitis.", "content": "The conservative treatment of hypertrophic gingivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008376"}
{"pmid": "21008375", "title": "The use of the central bearing point for balancing full upper and lower dentures.", "content": "The use of the central bearing point for balancing full upper and lower dentures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008375"}
{"pmid": "21008378", "title": "Case report of trifacial pain caused by a dentigerous cyst.", "content": "Case report of trifacial pain caused by a dentigerous cyst.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008378"}
{"pmid": "21008377", "title": "An allantoin-sulfathiazole combination in treating Vincent's infection.", "content": "An allantoin-sulfathiazole combination in treating Vincent's infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008377"}
{"pmid": "21008379", "title": "The aetiology of Vincent's gingivitis.", "content": "The aetiology of Vincent's gingivitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008379"}
{"pmid": "21008380", "title": "A vitallium implant as a bridge abutment.", "content": "A vitallium implant as a bridge abutment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008380"}
{"pmid": "21008381", "title": "Surgery of the month and jaws.", "content": "Surgery of the month and jaws.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008381"}
{"pmid": "21008382", "title": "The newer knowledge of hygiene in diet.", "content": "The newer knowledge of hygiene in diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008382"}
{"pmid": "21008383", "title": "Nutrition, a field for dental expansion.", "content": "Nutrition, a field for dental expansion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008383"}
{"pmid": "21008384", "title": "Some applications of stainless steel in orthodontics.", "content": "Some applications of stainless steel in orthodontics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008384"}
{"pmid": "21008385", "title": "Alternate anchylosis in the teeth of South African snakes.", "content": "Alternate anchylosis in the teeth of South African snakes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008385"}
{"pmid": "21008386", "title": "Drugs and prescriptions used in periodontia; their practical application.", "content": "Drugs and prescriptions used in periodontia; their practical application.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008386"}
{"pmid": "21008387", "title": "Painless treatment of vital dentin; a practical procedure with warm medicaments.", "content": "Painless treatment of vital dentin; a practical procedure with warm medicaments.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008387"}
{"pmid": "21008388", "title": "Postextraction bacteriemia prevented by sulfanilamide.", "content": "Postextraction bacteriemia prevented by sulfanilamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008388"}
{"pmid": "21008389", "title": "Use and abuse of sulfa drugs.", "content": "Use and abuse of sulfa drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008389"}
{"pmid": "21008390", "title": "Local application of sulfa drugs following extraction and oral surgery procedures.", "content": "Local application of sulfa drugs following extraction and oral surgery procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008390"}
{"pmid": "21008391", "title": "Sodium fluoride therapy for combating dentin sensitivity and gingival decay.", "content": "Sodium fluoride therapy for combating dentin sensitivity and gingival decay.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008391"}
{"pmid": "21008392", "title": "Treatment of mouth infections with sulfathiazole paste.", "content": "Treatment of mouth infections with sulfathiazole paste.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008392"}
{"pmid": "21008393", "title": "Topical application of sodium fluoride to control dental caries.", "content": "Topical application of sodium fluoride to control dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008393"}
{"pmid": "21008394", "title": "The use of penicillin by the dental general practitioner; penicillin-sulfanilamide cones for topical administration.", "content": "The use of penicillin by the dental general practitioner; penicillin-sulfanilamide cones for topical administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008394"}
{"pmid": "21008395", "title": "Penicillin and tyrothricin therapy in relation to dentistry and oral surgery.", "content": "Penicillin and tyrothricin therapy in relation to dentistry and oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008395"}
{"pmid": "21008396", "title": "Pressure anesthesia of the dental pulp, with procaine-penicillin paste.", "content": "Pressure anesthesia of the dental pulp, with procaine-penicillin paste.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008396"}
{"pmid": "21008397", "title": "A review of 510 complete dental examination records.", "content": "A review of 510 complete dental examination records.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008397"}
{"pmid": "21008398", "title": "Infected, impacted teeth.", "content": "Infected, impacted teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008398"}
{"pmid": "21008399", "title": "PENICILLIN and sulfonamides.", "content": "PENICILLIN and sulfonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008399"}
{"pmid": "21008400", "title": "CHROMIC acid leading choice for Vincent's infection therapy.", "content": "CHROMIC acid leading choice for Vincent's infection therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008400"}
{"pmid": "21008401", "title": "Dentistry in Norway.", "content": "Dentistry in Norway.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008401"}
{"pmid": "21008402", "title": "The organic constituent of enamel.", "content": "The organic constituent of enamel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008402"}
{"pmid": "21008403", "title": "Aerodontalgia.", "content": "Aerodontalgia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008403"}
{"pmid": "21008404", "title": "The electric pulp tester in oral diagnosis.", "content": "The electric pulp tester in oral diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008404"}
{"pmid": "21008405", "title": "The dental bacterial plague and its role in the caries process.", "content": "The dental bacterial plague and its role in the caries process.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008405"}
{"pmid": "21008406", "title": "Radioactive isotopes and their use in studying the metabolism of the calcified structures of the teeth.", "content": "Radioactive isotopes and their use in studying the metabolism of the calcified structures of the teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008406"}
{"pmid": "21008407", "title": "The estimation of polyvinyl alcohols in body fluids.", "content": "The estimation of polyvinyl alcohols in body fluids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008407"}
{"pmid": "21008408", "title": "The temperature verification test in serology.", "content": "The temperature verification test in serology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008408"}
{"pmid": "21008409", "title": "Histological technic.", "content": "Histological technic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008409"}
{"pmid": "21008410", "title": "The electron microscope.", "content": "The electron microscope.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008410"}
{"pmid": "21008411", "title": "Diets and food items for the experimental production of thiamin deficiency in man.", "content": "Diets and food items for the experimental production of thiamin deficiency in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008411"}
{"pmid": "21008412", "title": "Nutrients consumed by Army students at the University of Missouri.", "content": "Nutrients consumed by Army students at the University of Missouri.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008412"}
{"pmid": "21008413", "title": "Ascorbic acid content of food served in a cooperative residence hall for women.", "content": "Ascorbic acid content of food served in a cooperative residence hall for women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008413"}
{"pmid": "21008414", "title": "Dietary study of Cornell University women.", "content": "Dietary study of Cornell University women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008414"}
{"pmid": "21008415", "title": "Effect of quantity preparation procedures on vitamin retention; canned tomatoes.", "content": "Effect of quantity preparation procedures on vitamin retention; canned tomatoes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008415"}
{"pmid": "21008416", "title": "The administrative dietitian in industrial feeding.", "content": "The administrative dietitian in industrial feeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008416"}
{"pmid": "21008417", "title": "EDUCATIONAL qualifications of nutritionists in health agencies.", "content": "EDUCATIONAL qualifications of nutritionists in health agencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008417"}
{"pmid": "21008418", "title": "Nicotinic acid and the level of protein intake in the nutrition of the pig.", "content": "Nicotinic acid and the level of protein intake in the nutrition of the pig.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008418"}
{"pmid": "21008419", "title": "The therapeutic effect of yeast and pyridoxine on poikilocytosis in dairy cattle.", "content": "The therapeutic effect of yeast and pyridoxine on poikilocytosis in dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008419"}
{"pmid": "21008420", "title": "Field illumination and commercial handling as factors in determining the ascorbic acid content of tomatoes received at the cannery.", "content": "Field illumination and commercial handling as factors in determining the ascorbic acid content of tomatoes received at the cannery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008420"}
{"pmid": "21008421", "title": "The effect of manufacturing methods on the ascorbic acid content and consistency characteristics of tomato juice.", "content": "The effect of manufacturing methods on the ascorbic acid content and consistency characteristics of tomato juice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008421"}
{"pmid": "21008422", "title": "The elimination and distribution of selenium in the tissues in experimental selenium poisoning.", "content": "The elimination and distribution of selenium in the tissues in experimental selenium poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008422"}
{"pmid": "21008423", "title": "Secretion of vitamin D in milks of women fed fish liver oil.", "content": "Secretion of vitamin D in milks of women fed fish liver oil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008423"}
{"pmid": "21008424", "title": "Vitamin A requirements in calves.", "content": "Vitamin A requirements in calves.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008424"}
{"pmid": "21008425", "title": "The influence of ascorbic acid on the activity of gonadotropic hormones in guinea pigs.", "content": "The influence of ascorbic acid on the activity of gonadotropic hormones in guinea pigs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008425"}
{"pmid": "21008426", "title": "The availability of the iron in Hawaiian grown vegetables.", "content": "The availability of the iron in Hawaiian grown vegetables.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008426"}
{"pmid": "21008427", "title": "Silent gallstones.", "content": "Silent gallstones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008427"}
{"pmid": "21008428", "title": "Eosinophilia on a gastro-intestinal hospital service; case reports on four patients with a syndrome of eosinophila, leucocytosis and gastro-intestinal complaints.", "content": "Eosinophilia on a gastro-intestinal hospital service; case reports on four patients with a syndrome of eosinophila, leucocytosis and gastro-intestinal complaints.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008428"}
{"pmid": "21008429", "title": "A review of the gastro-enterologic roentgenologic literature for the year 1943.", "content": "A review of the gastro-enterologic roentgenologic literature for the year 1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008429"}
{"pmid": "21008430", "title": "Nutrition in the aged.", "content": "Nutrition in the aged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008430"}
{"pmid": "21008431", "title": "Enterogastrone, anthelone and urogastrone; a review of the literature and a suggestion for the organization of a national committee for the study of peptic ulcer.", "content": "Enterogastrone, anthelone and urogastrone; a review of the literature and a suggestion for the organization of a national committee for the study of peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008431"}
{"pmid": "21008432", "title": "Is bile and pancreatic juice a factor in the genesis of ulcerative colitis? an experimental study.", "content": "Is bile and pancreatic juice a factor in the genesis of ulcerative colitis? an experimental study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008432"}
{"pmid": "21008433", "title": "On the physiology of volatile fatty acids.", "content": "On the physiology of volatile fatty acids.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008433"}
{"pmid": "21008434", "title": "PUZZLING attacks of indigestion due to a latent infection with a cold virus.", "content": "PUZZLING attacks of indigestion due to a latent infection with a cold virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008434"}
{"pmid": "21008435", "title": "Diet and the teeth.", "content": "Diet and the teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008435"}
{"pmid": "21008436", "title": "Pattern reversal in the plumage of thiouracil-treated hybrid fowl.", "content": "Pattern reversal in the plumage of thiouracil-treated hybrid fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008436"}
{"pmid": "21008438", "title": "FAMILY allowances in Canada.", "content": "FAMILY allowances in Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008438"}
{"pmid": "21008437", "title": "A seedling method for testing aphid resistance, and its application to breeding and inheritance studies in cucurbits and other plants.", "content": "A seedling method for testing aphid resistance, and its application to breeding and inheritance studies in cucurbits and other plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008437"}
{"pmid": "21008439", "title": "Evaluation of species crosses of cattle by polyallel crossing; a study of zebu and Africander X Aberdeen-Angus cattle under subtropical conditions.", "content": "Evaluation of species crosses of cattle by polyallel crossing; a study of zebu and Africander X Aberdeen-Angus cattle under subtropical conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008439"}
{"pmid": "21008440", "title": "A dactylolysis mutation in the fowl.", "content": "A dactylolysis mutation in the fowl.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008440"}
{"pmid": "21008441", "title": "Art and mental disease.", "content": "Art and mental disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008441"}
{"pmid": "21008442", "title": "Artistic behavior of the mentally deranged.", "content": "Artistic behavior of the mentally deranged.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008442"}
{"pmid": "21008443", "title": "The art of schizophrenics.", "content": "The art of schizophrenics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008443"}
{"pmid": "21008444", "title": "Great artists who suffered from mental disorders.", "content": "Great artists who suffered from mental disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008444"}
{"pmid": "21008445", "title": "Analysis of Government records an emerging profession.", "content": "Analysis of Government records an emerging profession.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008445"}
{"pmid": "21008446", "title": "On the catalog card for a rare book.", "content": "On the catalog card for a rare book.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008446"}
{"pmid": "21008447", "title": "Uniform statistics for library holdings.", "content": "Uniform statistics for library holdings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008447"}
{"pmid": "21008448", "title": "A guide to radiographic interpretation of esophageal and gastric disorders.", "content": "A guide to radiographic interpretation of esophageal and gastric disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008448"}
{"pmid": "21008449", "title": "Continuous caudal analgesia during labor and delivery; a report of 750 cases.", "content": "Continuous caudal analgesia during labor and delivery; a report of 750 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008449"}
{"pmid": "21008450", "title": "The effect upon health of restrictions of the motility of the lower bowel.", "content": "The effect upon health of restrictions of the motility of the lower bowel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008450"}
{"pmid": "21008451", "title": "Foreign bodies in the nasal passages.", "content": "Foreign bodies in the nasal passages.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008451"}
{"pmid": "21008452", "title": "MODERN nurses home at Queen Charlotte's Maternity Hospital, London.", "content": "MODERN nurses home at Queen Charlotte's Maternity Hospital, London.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008452"}
{"pmid": "21008453", "title": "OAK RIDGE HOSPITAL: high-speed development of hospital facilities for atomic bomb workers.", "content": "OAK RIDGE HOSPITAL: high-speed development of hospital facilities for atomic bomb workers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008453"}
{"pmid": "21008454", "title": "Some notes on water treatment.", "content": "Some notes on water treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008454"}
{"pmid": "21008455", "title": "Consents to operations and other surgical procedures; patients other than mental or mental deficiency cases.", "content": "Consents to operations and other surgical procedures; patients other than mental or mental deficiency cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008455"}
{"pmid": "21008456", "title": "The key to emergency care is cooperation.", "content": "The key to emergency care is cooperation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008456"}
{"pmid": "21008457", "title": "PROGRESS in veterans' relations through new methods.", "content": "PROGRESS in veterans' relations through new methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008457"}
{"pmid": "21008458", "title": "President Truman's proposed national health program in Perspective.", "content": "President Truman's proposed national health program in Perspective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008458"}
{"pmid": "21008459", "title": "Administration of an effective pharmacy requires a sound policy.", "content": "Administration of an effective pharmacy requires a sound policy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008459"}
{"pmid": "21008460", "title": "Convalescent care; a neglected factor?", "content": "Convalescent care; a neglected factor?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008460"}
{"pmid": "21008461", "title": "A program to step up the autopsy rate is essential.", "content": "A program to step up the autopsy rate is essential.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008461"}
{"pmid": "21008462", "title": "FULL text of S. 191, as adopted by the United States Senate.", "content": "FULL text of S. 191, as adopted by the United States Senate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008462"}
{"pmid": "21008463", "title": "Preliminary report on the use of tantalum oxide, Type 400.", "content": "Preliminary report on the use of tantalum oxide, Type 400.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008463"}
{"pmid": "21008464", "title": "Rates of absenteeism and turnover in personnel in relation to employees' work attitudes.", "content": "Rates of absenteeism and turnover in personnel in relation to employees' work attitudes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008464"}
{"pmid": "21008465", "title": "Industrial health in small plants.", "content": "Industrial health in small plants.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008465"}
{"pmid": "21008466", "title": "A discussion of the commoner industrial dermatoses.", "content": "A discussion of the commoner industrial dermatoses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008466"}
{"pmid": "21008467", "title": "Alphatron radon ointment in industrial practice.", "content": "Alphatron radon ointment in industrial practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008467"}
{"pmid": "21008468", "title": "Industrial medical services.", "content": "Industrial medical services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008468"}
{"pmid": "21008469", "title": "Controlled industrial sanitation.", "content": "Controlled industrial sanitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008469"}
{"pmid": "21008470", "title": "Industrial dentistry.", "content": "Industrial dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008470"}
{"pmid": "21008471", "title": "Organization and operation of the industrial diagnostic service of the Chicago Dental Society.", "content": "Organization and operation of the industrial diagnostic service of the Chicago Dental Society.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008471"}
{"pmid": "21008472", "title": "Progress of a dental program.", "content": "Progress of a dental program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008472"}
{"pmid": "21008480", "title": "The differential diagnosis of bovine brucellosis from the bactericidal action of blood plasma.", "content": "The differential diagnosis of bovine brucellosis from the bactericidal action of blood plasma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008480"}
{"pmid": "21008494", "title": "Esophageal lesions associated with acrosclerosis and scleroderma.", "content": "Esophageal lesions associated with acrosclerosis and scleroderma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008494"}
{"pmid": "21008495", "title": "Neurologic complications during meningococcic meningitis treated with sulfonamide drugs.", "content": "Neurologic complications during meningococcic meningitis treated with sulfonamide drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008495"}
{"pmid": "21008496", "title": "An account of stock.", "content": "An account of stock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008496"}
{"pmid": "21008497", "title": "Absence of electrocardiographic changes in Tsutsugamushi fever (scrub typhus); report of two hundred consecutive cases.", "content": "Absence of electrocardiographic changes in Tsutsugamushi fever (scrub typhus); report of two hundred consecutive cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008497"}
{"pmid": "21008498", "title": "South American trypanosomiasis (Chagas' disease).", "content": "South American trypanosomiasis (Chagas' disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008498"}
{"pmid": "21008499", "title": "Sickle cell anemia in white patients with ulcers of the ankles; report of two cases.", "content": "Sickle cell anemia in white patients with ulcers of the ankles; report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008499"}
{"pmid": "21008500", "title": "Clinical syndrome in patients with pulmonary embolism.", "content": "Clinical syndrome in patients with pulmonary embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008500"}
{"pmid": "21008501", "title": "Blood; a review of the recent literature.", "content": "Blood; a review of the recent literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008501"}
{"pmid": "21008508", "title": "[Basic problems of experimental oncology].", "content": "[Basic problems of experimental oncology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008508"}
{"pmid": "21008509", "title": "[Contribution to the role of heredity in the etiology of cancer].", "content": "[Contribution to the role of heredity in the etiology of cancer].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008509"}
{"pmid": "21008510", "title": "[On the quantitative distribution of cancerogeneous hydrocarbons in an animal organism].", "content": "[On the quantitative distribution of cancerogeneous hydrocarbons in an animal organism].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008510"}
{"pmid": "21008511", "title": "[Some data on the question of transplantability of malignant tumors of organs of a blastomatous animal].", "content": "[Some data on the question of transplantability of malignant tumors of organs of a blastomatous animal].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008511"}
{"pmid": "21008512", "title": "[On the transplantation of mouse sarcoma by the liver of a blastomatous animal].", "content": "[On the transplantation of mouse sarcoma by the liver of a blastomatous animal].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008512"}
{"pmid": "21008513", "title": "[The morbid morphology of man brucellosis].", "content": "[The morbid morphology of man brucellosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008513"}
{"pmid": "21008515", "title": "[Morphological changes of the blood and blood forming apparatus under action of UHF currents].", "content": "[Morphological changes of the blood and blood forming apparatus under action of UHF currents].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008515"}
{"pmid": "21008514", "title": "[Morphological changes of the liver in experimental ileus].", "content": "[Morphological changes of the liver in experimental ileus].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008514"}
{"pmid": "21008516", "title": "[The changes of the nervous elements of the skin and some other organs in typhus exanthematicus].", "content": "[The changes of the nervous elements of the skin and some other organs in typhus exanthematicus].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008516"}
{"pmid": "21008517", "title": "[Reactive changes of the motor nervous endings of the skeletal muscle in experimental ischemia].", "content": "[Reactive changes of the motor nervous endings of the skeletal muscle in experimental ischemia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008517"}
{"pmid": "21008518", "title": "[Experimental nephritic hypertony in dogs].", "content": "[Experimental nephritic hypertony in dogs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008518"}
{"pmid": "21008519", "title": "[New ways of epilepsy diagnosis].", "content": "[New ways of epilepsy diagnosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008519"}
{"pmid": "21008520", "title": "[A peculiarity of insulin shock aggravated by C avitaminosis].", "content": "[A peculiarity of insulin shock aggravated by C avitaminosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008520"}
{"pmid": "21008521", "title": "[The mechanism of the action of synatren].", "content": "[The mechanism of the action of synatren].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008521"}
{"pmid": "21008522", "title": "[Oxidation-reduction processes occurring in the mucosa of the stomach in connection with secretion; first communication; the effect of food irritator].", "content": "[Oxidation-reduction processes occurring in the mucosa of the stomach in connection with secretion; first communication; the effect of food irritator].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008522"}
{"pmid": "21008523", "title": "[On the biological role of the salts of the elements present in the organism in minimum quantities; contribution to the role of fluor on hydrocarbon metabolism].", "content": "[On the biological role of the salts of the elements present in the organism in minimum quantities; contribution to the role of fluor on hydrocarbon metabolism].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008523"}
{"pmid": "21008524", "title": "[Contents of nitrogen in various architectonic formations of the cortex of the brain].", "content": "[Contents of nitrogen in various architectonic formations of the cortex of the brain].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008524"}
{"pmid": "21008525", "title": "[Desamination of certain amino acids in the organism (angio-chemical examination)].", "content": "[Desamination of certain amino acids in the organism (angio-chemical examination)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008525"}
{"pmid": "21008526", "title": "[Proteinic dissolution of tissue in burns].", "content": "[Proteinic dissolution of tissue in burns].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008526"}
{"pmid": "21008527", "title": "[On the role of acetylcholine in the mechanism of the rise of nerve refractoriness].", "content": "[On the role of acetylcholine in the mechanism of the rise of nerve refractoriness].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008527"}
{"pmid": "21008528", "title": "[The effect of eserin on spinal shock].", "content": "[The effect of eserin on spinal shock].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008528"}
{"pmid": "21008529", "title": "[Contribution to the summational and accomodational processes in central inhibition, provoked by the rare electrical irritation of the afferent nerve].", "content": "[Contribution to the summational and accomodational processes in central inhibition, provoked by the rare electrical irritation of the afferent nerve].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008529"}
{"pmid": "21008530", "title": "The surgery of arterial disease and injury.", "content": "The surgery of arterial disease and injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008530"}
{"pmid": "21008531", "title": "Observations on cases of starvation at Belsen.", "content": "Observations on cases of starvation at Belsen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008531"}
{"pmid": "21008532", "title": "D.B.E.: a new synthetic oestrogen.", "content": "D.B.E.: a new synthetic oestrogen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008532"}
{"pmid": "21008533", "title": "D.B.E. in treatment of menopausal symptoms.", "content": "D.B.E. in treatment of menopausal symptoms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008533"}
{"pmid": "21008534", "title": "Concentrating malaria parasites in thin films.", "content": "Concentrating malaria parasites in thin films.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008534"}
{"pmid": "21008535", "title": "Immunity to sandfly fever.", "content": "Immunity to sandfly fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008535"}
{"pmid": "21008536", "title": "A case of locked twins.", "content": "A case of locked twins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008536"}
{"pmid": "21008537", "title": "The Herbal of Rufinus.", "content": "The Herbal of Rufinus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008537"}
{"pmid": "21008538", "title": "Ocular signs in the prisoner of war returned from the Far East.", "content": "Ocular signs in the prisoner of war returned from the Far East.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008538"}
{"pmid": "21008539", "title": "Paracentesis and myringotomy; a question of terminology.", "content": "Paracentesis and myringotomy; a question of terminology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008539"}
{"pmid": "21008540", "title": "DESIGN and craftsmanship for the tuberculous.", "content": "DESIGN and craftsmanship for the tuberculous.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008540"}
{"pmid": "21008541", "title": "Operation for varicose veins.", "content": "Operation for varicose veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008541"}
{"pmid": "21008542", "title": "Non-specific mesenteric lymphadenitis.", "content": "Non-specific mesenteric lymphadenitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008542"}
{"pmid": "21008543", "title": "Hospital reforms.", "content": "Hospital reforms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008543"}
{"pmid": "21008571", "title": "Marihuana.", "content": "Marihuana.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008571"}
{"pmid": "21008572", "title": "The treatment of varicose veins.", "content": "The treatment of varicose veins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008572"}
{"pmid": "21008573", "title": "Placental permeability.", "content": "Placental permeability.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008573"}
{"pmid": "21008574", "title": "Physiologic changes associated with varicose veins and their correction.", "content": "Physiologic changes associated with varicose veins and their correction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008574"}
{"pmid": "21008575", "title": "Functions and connections of the medial lemniscus.", "content": "Functions and connections of the medial lemniscus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008575"}
{"pmid": "21008578", "title": "Clinical and electrocardiographic response to N-methylnicotinamide chloride administration in man.", "content": "Clinical and electrocardiographic response to N-methylnicotinamide chloride administration in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008578"}
{"pmid": "21008576", "title": "Epivascular choroidal pigment streaks, their pathology and possible prognostic significance.", "content": "Epivascular choroidal pigment streaks, their pathology and possible prognostic significance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008576"}
{"pmid": "21008577", "title": "The significance of streptococci isolated from the female urinary tract.", "content": "The significance of streptococci isolated from the female urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008577"}
{"pmid": "21008579", "title": "Lipid response to vitamin A administration; a possible test for vitamin A deficiency.", "content": "Lipid response to vitamin A administration; a possible test for vitamin A deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008579"}
{"pmid": "21008580", "title": "Genito-urinary tuberculosis.", "content": "Genito-urinary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008580"}
{"pmid": "21008581", "title": "Solitary systolic murmurs.", "content": "Solitary systolic murmurs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008581"}
{"pmid": "21008582", "title": "Typhoid fever.", "content": "Typhoid fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008582"}
{"pmid": "21008583", "title": "Starving the bacteria; how new drugs are developed.", "content": "Starving the bacteria; how new drugs are developed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008583"}
{"pmid": "21008584", "title": "A case of ulcerative endocarditis treated with sulphadiazine and inductothermy.", "content": "A case of ulcerative endocarditis treated with sulphadiazine and inductothermy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008584"}
{"pmid": "21008585", "title": "ARTIFICIAL insemination.", "content": "ARTIFICIAL insemination.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008585"}
{"pmid": "21008586", "title": "Cardiotoxin inhibitors.", "content": "Cardiotoxin inhibitors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008586"}
{"pmid": "21008587", "title": "Penicillin therapy of rabbit syphilis.", "content": "Penicillin therapy of rabbit syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008587"}
{"pmid": "21008588", "title": "Technique of carotid sinus stimulation.", "content": "Technique of carotid sinus stimulation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008588"}
{"pmid": "21008589", "title": "Variations in size of human stomach.", "content": "Variations in size of human stomach.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008589"}
{"pmid": "21008590", "title": "Anatomical demonstration of the anovulatory menstrual cycle.", "content": "Anatomical demonstration of the anovulatory menstrual cycle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008590"}
{"pmid": "21008591", "title": "Introspection and the orbital cortex.", "content": "Introspection and the orbital cortex.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008591"}
{"pmid": "21008592", "title": "Early public health in California.", "content": "Early public health in California.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008592"}
{"pmid": "21008593", "title": "The development and present status of social security in Canada.", "content": "The development and present status of social security in Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008593"}
{"pmid": "21008594", "title": "Recovery and rehabilitation.", "content": "Recovery and rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008594"}
{"pmid": "21008595", "title": "Planned health in Saskatchewan.", "content": "Planned health in Saskatchewan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008595"}
{"pmid": "21008596", "title": "Evaluation of renal function in man.", "content": "Evaluation of renal function in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008596"}
{"pmid": "21008597", "title": "A co-operative group clinic.", "content": "A co-operative group clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008597"}
{"pmid": "21008598", "title": "Some notes on interning.", "content": "Some notes on interning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008598"}
{"pmid": "21008601", "title": "Some practical facts about Salmonella infections.", "content": "Some practical facts about Salmonella infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008601"}
{"pmid": "21008600", "title": "Student internship in Canadian hospitals.", "content": "Student internship in Canadian hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008600"}
{"pmid": "21008602", "title": "The expansion of the Connecticut Cancer Program.", "content": "The expansion of the Connecticut Cancer Program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008602"}
{"pmid": "21008603", "title": "Duplication cyst of the terminal ileum with acute inflammatory reaction; report of a case.", "content": "Duplication cyst of the terminal ileum with acute inflammatory reaction; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008603"}
{"pmid": "21008604", "title": "Adenocarcinoma of the jejunum arising around polyps.", "content": "Adenocarcinoma of the jejunum arising around polyps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008604"}
{"pmid": "21008605", "title": "Vitamin D poisoning; hypercalcemia; case report.", "content": "Vitamin D poisoning; hypercalcemia; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008605"}
{"pmid": "21008606", "title": "A plan to augment graduate medical training.", "content": "A plan to augment graduate medical training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008606"}
{"pmid": "21008607", "title": "Expansion of voluntary group health care progress.", "content": "Expansion of voluntary group health care progress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008607"}
{"pmid": "21008608", "title": "The veteran and tuberculosis.", "content": "The veteran and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008608"}
{"pmid": "21008609", "title": "Public relations as the doctor's individual responsibility.", "content": "Public relations as the doctor's individual responsibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008609"}
{"pmid": "21008610", "title": "Suggested school health policies.", "content": "Suggested school health policies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008610"}
{"pmid": "21008611", "title": "New law covers registration of laboratories examining milk or milk products.", "content": "New law covers registration of laboratories examining milk or milk products.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008611"}
{"pmid": "21008618", "title": "The limits and achievements of modern x-ray tube construction.", "content": "The limits and achievements of modern x-ray tube construction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008618"}
{"pmid": "21008652", "title": "Nonspecific reactions in routine blood testing for syphilis.", "content": "Nonspecific reactions in routine blood testing for syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008652"}
{"pmid": "21008653", "title": "Alkali treatment of methyl alcohol poisoning.", "content": "Alkali treatment of methyl alcohol poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008653"}
{"pmid": "21008654", "title": "The in vitro action of streptomycin on bacteria.", "content": "The in vitro action of streptomycin on bacteria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008654"}
{"pmid": "21008656", "title": "Backache.", "content": "Backache.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008656"}
{"pmid": "21008655", "title": "Occurrence of Brucella melitensis in Iowa.", "content": "Occurrence of Brucella melitensis in Iowa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008655"}
{"pmid": "21008657", "title": "Dyspnea in hemophilia from hemorrhage into larynx.", "content": "Dyspnea in hemophilia from hemorrhage into larynx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008657"}
{"pmid": "21008658", "title": "Iodized salt for the prophylaxis of endemic goiter.", "content": "Iodized salt for the prophylaxis of endemic goiter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008658"}
{"pmid": "21008659", "title": "MEDICINE and the changing order.", "content": "MEDICINE and the changing order.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008659"}
{"pmid": "21008660", "title": "Treatment of mixed infections with penicillin; with special reference to the adjuvant action of parachlorophenol.", "content": "Treatment of mixed infections with penicillin; with special reference to the adjuvant action of parachlorophenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008660"}
{"pmid": "21008661", "title": "Chemoprophylaxis and sulfonamide resistant streptococci.", "content": "Chemoprophylaxis and sulfonamide resistant streptococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008661"}
{"pmid": "21008662", "title": "The treatment of compound fractures of the femur.", "content": "The treatment of compound fractures of the femur.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008662"}
{"pmid": "21008663", "title": "Meat in the diet of pregnant women.", "content": "Meat in the diet of pregnant women.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008663"}
{"pmid": "21008665", "title": "Isospora hominis infection in man.", "content": "Isospora hominis infection in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008665"}
{"pmid": "21008664", "title": "Reexamination of veterans discharged because of heart disease or hypertension.", "content": "Reexamination of veterans discharged because of heart disease or hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008664"}
{"pmid": "21008666", "title": "Brain abscess associated with congenital heart disease; report of a case with complete recovery.", "content": "Brain abscess associated with congenital heart disease; report of a case with complete recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008666"}
{"pmid": "21008667", "title": "DEATHS of physicians in 1945.", "content": "DEATHS of physicians in 1945.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008667"}
{"pmid": "21008669", "title": "DRUNKENNESS: probative value of chemical tests showing nonintoxication is question for jury.", "content": "DRUNKENNESS: probative value of chemical tests showing nonintoxication is question for jury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008669"}
{"pmid": "21008668", "title": "An early observation on penicillin.", "content": "An early observation on penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008668"}
{"pmid": "21008670", "title": "Gynaecology and obstetrics in the Missionary Medical College Hospital.", "content": "Gynaecology and obstetrics in the Missionary Medical College Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008670"}
{"pmid": "21008671", "title": "The importance of newer methods of examination in early diagnosis of chest diseases.", "content": "The importance of newer methods of examination in early diagnosis of chest diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008671"}
{"pmid": "21008672", "title": "Incompatibility.", "content": "Incompatibility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008672"}
{"pmid": "21008673", "title": "A health insurance plan for Christians.", "content": "A health insurance plan for Christians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008673"}
{"pmid": "21008674", "title": "Twin intra-uterine pregnancy with an ectopic pregnancy complicating osteomalacia.", "content": "Twin intra-uterine pregnancy with an ectopic pregnancy complicating osteomalacia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008674"}
{"pmid": "21008675", "title": "Congenital malformation of the mesentery; a report of two cases.", "content": "Congenital malformation of the mesentery; a report of two cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008675"}
{"pmid": "21008680", "title": "Indiana's health program.", "content": "Indiana's health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008680"}
{"pmid": "21008681", "title": "Medicine in the postwar world.", "content": "Medicine in the postwar world.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008681"}
{"pmid": "21008682", "title": "Osteomyelitis; treatment by radical saucerization and early skin grafting.", "content": "Osteomyelitis; treatment by radical saucerization and early skin grafting.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008682"}
{"pmid": "21008683", "title": "The relation between trauma and malignant disease.", "content": "The relation between trauma and malignant disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008683"}
{"pmid": "21008684", "title": "Lung abscess.", "content": "Lung abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008684"}
{"pmid": "21008685", "title": "Menière's syndrome.", "content": "Menière's syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008685"}
{"pmid": "21008686", "title": "Nursing service needs.", "content": "Nursing service needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008686"}
{"pmid": "21008687", "title": "Behavior problems and habit disturbances in pre-adolescent children; their meaning and management.", "content": "Behavior problems and habit disturbances in pre-adolescent children; their meaning and management.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008687"}
{"pmid": "21008688", "title": "Use of penicillin ointment in treatment of impetigo and other conditions of the skin.", "content": "Use of penicillin ointment in treatment of impetigo and other conditions of the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008688"}
{"pmid": "21008689", "title": "Syphilis: considerations in diagnosis.", "content": "Syphilis: considerations in diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008689"}
{"pmid": "21008690", "title": "The pathology of bismuth poisoning.", "content": "The pathology of bismuth poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008690"}
{"pmid": "21008691", "title": "Arsenical exfoliative dermatitis co-incidental with acute hemorrhagic nephritis; case report.", "content": "Arsenical exfoliative dermatitis co-incidental with acute hemorrhagic nephritis; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008691"}
{"pmid": "21008692", "title": "Surgical treatment of inguinal hernia.", "content": "Surgical treatment of inguinal hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008692"}
{"pmid": "21008693", "title": "The evaluation of various case finding procedures in a tuberculosis control program.", "content": "The evaluation of various case finding procedures in a tuberculosis control program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008693"}
{"pmid": "21008694", "title": "Further data on the pathogenesis of fibroblastic neoplasms; density ratio of tissue computed by the author's exposure meter method.", "content": "Further data on the pathogenesis of fibroblastic neoplasms; density ratio of tissue computed by the author's exposure meter method.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008694"}
{"pmid": "21008695", "title": "Lipoid nephrosis; a review of the disease with report of case.", "content": "Lipoid nephrosis; a review of the disease with report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008695"}
{"pmid": "21008696", "title": "Neurosyphilis; its diagnosis and treatment.", "content": "Neurosyphilis; its diagnosis and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008696"}
{"pmid": "21008697", "title": "Clinical experiences in the treatment of low back and sciatic pain associated with disorders of the intervertebral disc.", "content": "Clinical experiences in the treatment of low back and sciatic pain associated with disorders of the intervertebral disc.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008697"}
{"pmid": "21008698", "title": "Primary cysts of the omentum.", "content": "Primary cysts of the omentum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008698"}
{"pmid": "21008700", "title": "Common macrocytic anemias.", "content": "Common macrocytic anemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008700"}
{"pmid": "21008699", "title": "The use of curare (introcostrin) in reducing convulsive effects of tetanus.", "content": "The use of curare (introcostrin) in reducing convulsive effects of tetanus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008699"}
{"pmid": "21008701", "title": "Toxic psychosis due to bromides.", "content": "Toxic psychosis due to bromides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008701"}
{"pmid": "21008702", "title": "The problem of hypertension.", "content": "The problem of hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008702"}
{"pmid": "21008703", "title": "Rabies.", "content": "Rabies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008703"}
{"pmid": "21008704", "title": "[Neuropathological syndromes in traumatic damages of the thorax].", "content": "[Neuropathological syndromes in traumatic damages of the thorax].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008704"}
{"pmid": "21008705", "title": "[On therapeutic illnesses in gunshot wounds and contusions].", "content": "[On therapeutic illnesses in gunshot wounds and contusions].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008705"}
{"pmid": "21008706", "title": "[Analysis of diagnostical errors in discrimination of lung tuberculosis].", "content": "[Analysis of diagnostical errors in discrimination of lung tuberculosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008706"}
{"pmid": "21008707", "title": "[Lung cancer simulating tuberculosis].", "content": "[Lung cancer simulating tuberculosis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008707"}
{"pmid": "21008708", "title": "[Dynamic spirometry as a method of examination of the functional capacity of the apparatus of blood circulation and respiration in the evaluation of work- and battle-capacity].", "content": "[Dynamic spirometry as a method of examination of the functional capacity of the apparatus of blood circulation and respiration in the evaluation of work- and battle-capacity].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008708"}
{"pmid": "21008709", "title": "[Partial electrocardiogram and IVth abductio in infarcts of the myocardium].", "content": "[Partial electrocardiogram and IVth abductio in infarcts of the myocardium].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008709"}
{"pmid": "21008710", "title": "[Roentgenological data on deformations of the gastrointestinal tract in hypertonic disease].", "content": "[Roentgenological data on deformations of the gastrointestinal tract in hypertonic disease].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008710"}
{"pmid": "21008711", "title": "[On employment of medical physical culture in hypertonic disease].", "content": "[On employment of medical physical culture in hypertonic disease].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008711"}
{"pmid": "21008712", "title": "[The rates and dynamics of venous pressure in healthy men].", "content": "[The rates and dynamics of venous pressure in healthy men].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008712"}
{"pmid": "21008713", "title": "[The normal figures of venous pressure and some physiological oscillations of it].", "content": "[The normal figures of venous pressure and some physiological oscillations of it].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008713"}
{"pmid": "21008714", "title": "[Employment of nicotinic acid in acute hepatitis].", "content": "[Employment of nicotinic acid in acute hepatitis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008714"}
{"pmid": "21008715", "title": "[Pathomorphological deformations in the lungs in the so-called alimentary-toxical aleikia].", "content": "[Pathomorphological deformations in the lungs in the so-called alimentary-toxical aleikia].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008715"}
{"pmid": "21008716", "title": "[Clinico-diagnostical peculiarities of various forms of dysentery].", "content": "[Clinico-diagnostical peculiarities of various forms of dysentery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008716"}
{"pmid": "21008717", "title": "[The clinics of the sting of the beetle cara-court].", "content": "[The clinics of the sting of the beetle cara-court].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008717"}
{"pmid": "21008718", "title": "[The effect of the reduced atmospheric pressure on hemodynamics].", "content": "[The effect of the reduced atmospheric pressure on hemodynamics].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008718"}
{"pmid": "21008719", "title": "[Phenomenon of auto-agglutination in both hypertonic disease and angiospastic syndrome].", "content": "[Phenomenon of auto-agglutination in both hypertonic disease and angiospastic syndrome].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008719"}
{"pmid": "21008720", "title": "[Contribution to the sulphidinotherapy of estival diarrheas].", "content": "[Contribution to the sulphidinotherapy of estival diarrheas].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008720"}
{"pmid": "21008721", "title": "[Dynamic observations on the capillaries in stenocardia and infarcts of the myocardium].", "content": "[Dynamic observations on the capillaries in stenocardia and infarcts of the myocardium].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008721"}
{"pmid": "21008722", "title": "[The role of coronary atherosclerosis in the functional disturbance of the coronary blood circulation, in the pathogenesis of the obturatio acuta of the coronal arteries and acute infarctis of the myocardium].", "content": "[The role of coronary atherosclerosis in the functional disturbance of the coronary blood circulation, in the pathogenesis of the obturatio acuta of the coronal arteries and acute infarctis of the myocardium].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008722"}
{"pmid": "21008723", "title": "[New problems of the clinical forms, early diagnosis and treatment of tetanus and in particular a local one].", "content": "[New problems of the clinical forms, early diagnosis and treatment of tetanus and in particular a local one].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008723"}
{"pmid": "21008724", "title": "[On indications and technics of removal of gunshot foreign bodies from the heart and pericardium].", "content": "[On indications and technics of removal of gunshot foreign bodies from the heart and pericardium].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008724"}
{"pmid": "21008725", "title": "[Renal hypertony in a dog (experimental investigation)].", "content": "[Renal hypertony in a dog (experimental investigation)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008725"}
{"pmid": "21008726", "title": "[Some questions of clinics and therapy of poisoning with hibernated corns (so-called septic angina or alimentary toxical aleikia)].", "content": "[Some questions of clinics and therapy of poisoning with hibernated corns (so-called septic angina or alimentary toxical aleikia)].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008726"}
{"pmid": "21008727", "title": "[Dynamics of oxygen starvation of the septic sick under treatment with massive doses of streptocide].", "content": "[Dynamics of oxygen starvation of the septic sick under treatment with massive doses of streptocide].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008727"}
{"pmid": "21008728", "title": "[The effect of massive doses of streptocide on the state of the acidous-alkaline balance in septic patients and in healthy men].", "content": "[The effect of massive doses of streptocide on the state of the acidous-alkaline balance in septic patients and in healthy men].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008728"}
{"pmid": "21008729", "title": "[Some data on the state of the cardiovascular system in anaerobic infection].", "content": "[Some data on the state of the cardiovascular system in anaerobic infection].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008729"}
{"pmid": "21008730", "title": "[Aqueous metabolism in rheumatism; pathogenesis of disturbances of aqueous metabolism in rheumatism].", "content": "[Aqueous metabolism in rheumatism; pathogenesis of disturbances of aqueous metabolism in rheumatism].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008730"}
{"pmid": "21008731", "title": "[On hemorrhagic pleuritis in lung cancer].", "content": "[On hemorrhagic pleuritis in lung cancer].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008731"}
{"pmid": "21008732", "title": "[Transfusion of the blood of hypertonics and its effect on hematopoesis].", "content": "[Transfusion of the blood of hypertonics and its effect on hematopoesis].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008732"}
{"pmid": "21008733", "title": "[Early amyloid nephrosis in complications of war traumae of bone].", "content": "[Early amyloid nephrosis in complications of war traumae of bone].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008733"}
{"pmid": "21008734", "title": "[Clinics of strongyloidosis of the lungs].", "content": "[Clinics of strongyloidosis of the lungs].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008734"}
{"pmid": "21008735", "title": "[On the vegeto-syndromes in war traumae].", "content": "[On the vegeto-syndromes in war traumae].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008735"}
{"pmid": "21008736", "title": "[Endocrine system and bronchial asthma].", "content": "[Endocrine system and bronchial asthma].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008736"}
{"pmid": "21008737", "title": "[New ways in the therapy of syphilis; experiment in the treatment of syphilis with penicillin].", "content": "[New ways in the therapy of syphilis; experiment in the treatment of syphilis with penicillin].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008737"}
{"pmid": "21008738", "title": "[On the pathogenesis and experimental therapy of trophic ulcers].", "content": "[On the pathogenesis and experimental therapy of trophic ulcers].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008738"}
{"pmid": "21008739", "title": "[Neuro-tropic factor in hematology].", "content": "[Neuro-tropic factor in hematology].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008739"}
{"pmid": "21008740", "title": "[Quick's test of the liver in clinics of surgical illnesses].", "content": "[Quick's test of the liver in clinics of surgical illnesses].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008740"}
{"pmid": "21008742", "title": "[Some questions of etiology, pathogenesis and differentiation of various forms of diabetes insipidus].", "content": "[Some questions of etiology, pathogenesis and differentiation of various forms of diabetes insipidus].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008742"}
{"pmid": "21008741", "title": "[On the mechanism of the effect of raw vegetative food on excretion of sterins from the organism].", "content": "[On the mechanism of the effect of raw vegetative food on excretion of sterins from the organism].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008741"}
{"pmid": "21008743", "title": "[The changes of ketonemia in pains and after injection of vitamin B1].", "content": "[The changes of ketonemia in pains and after injection of vitamin B1].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008743"}
{"pmid": "21008744", "title": "[Aleukemic syndrome in tuberculous splenomegaly].", "content": "[Aleukemic syndrome in tuberculous splenomegaly].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008744"}
{"pmid": "21008745", "title": "[The blood complement in dysentery].", "content": "[The blood complement in dysentery].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008745"}
{"pmid": "21008746", "title": "[Bilirubin in various forms of icterus under the influence of atropine infusion].", "content": "[Bilirubin in various forms of icterus under the influence of atropine infusion].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008746"}
{"pmid": "21008747", "title": "[The course of acute epithelial hepatitis in pregnant women].", "content": "[The course of acute epithelial hepatitis in pregnant women].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008747"}
{"pmid": "21008748", "title": "[On the chemotherapy of experimental infection by anthrax].", "content": "[On the chemotherapy of experimental infection by anthrax].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008748"}
{"pmid": "21008749", "title": "Psychiatric lessons from active service.", "content": "Psychiatric lessons from active service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008749"}
{"pmid": "21008750", "title": "Comparative effect of sulphonamide and penicillin in pneumonia.", "content": "Comparative effect of sulphonamide and penicillin in pneumonia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008750"}
{"pmid": "21008751", "title": "Mass radiography.", "content": "Mass radiography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008751"}
{"pmid": "21008752", "title": "Inguinal hernia; the new muscular internal ring.", "content": "Inguinal hernia; the new muscular internal ring.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008752"}
{"pmid": "21008753", "title": "Thoughts on sprue after experience in India.", "content": "Thoughts on sprue after experience in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008753"}
{"pmid": "21008755", "title": "Aseptic necrosis at sites of continuous intramuscular penicillin infusion.", "content": "Aseptic necrosis at sites of continuous intramuscular penicillin infusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008755"}
{"pmid": "21008754", "title": "Infusion into the internal saphenous vein at the ankle.", "content": "Infusion into the internal saphenous vein at the ankle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008754"}
{"pmid": "21008756", "title": "THAT FLU vaccine.", "content": "THAT FLU vaccine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008756"}
{"pmid": "21008757", "title": "Incidence of infections in war-time day nurseries.", "content": "Incidence of infections in war-time day nurseries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008757"}
{"pmid": "21008758", "title": "TAKING stock.", "content": "TAKING stock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008758"}
{"pmid": "21008759", "title": "Prognosis and the patient.", "content": "Prognosis and the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008759"}
{"pmid": "21008760", "title": "A transmissible disease in rats inoculated with material from cases of infective hepatitis.", "content": "A transmissible disease in rats inoculated with material from cases of infective hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008760"}
{"pmid": "21008761", "title": "Delimitation of subcortical tumours by direct electrography.", "content": "Delimitation of subcortical tumours by direct electrography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008761"}
{"pmid": "21008762", "title": "Schistosomiasis; intensive treatment with antimony.", "content": "Schistosomiasis; intensive treatment with antimony.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008762"}
{"pmid": "21008763", "title": "Treatment of schistosomiasis.", "content": "Treatment of schistosomiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008763"}
{"pmid": "21008764", "title": "Large missile lodged in the face; with minor clinical disturbance.", "content": "Large missile lodged in the face; with minor clinical disturbance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008764"}
{"pmid": "21008765", "title": "Determination of pathogenicity of tubercle bacilli by their intermediate metabolism.", "content": "Determination of pathogenicity of tubercle bacilli by their intermediate metabolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008765"}
{"pmid": "21008766", "title": "Para-aminosalicylic acid in the treatment of tuberculosis.", "content": "Para-aminosalicylic acid in the treatment of tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008766"}
{"pmid": "21008767", "title": "Prevention of accident and limitation of injury.", "content": "Prevention of accident and limitation of injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008767"}
{"pmid": "21008768", "title": "Biological dangers from atomic fission.", "content": "Biological dangers from atomic fission.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008768"}
{"pmid": "21008769", "title": "Aseptic necrosis after penicillin therapy.", "content": "Aseptic necrosis after penicillin therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008769"}
{"pmid": "21008770", "title": "MICROFILM and medical literature.", "content": "MICROFILM and medical literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008770"}
{"pmid": "21008771", "title": "Uterine bleeding.", "content": "Uterine bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008771"}
{"pmid": "21008772", "title": "Everyday orthopedics.", "content": "Everyday orthopedics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008772"}
{"pmid": "21008773", "title": "Jaundice in pregnancy.", "content": "Jaundice in pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008773"}
{"pmid": "21008774", "title": "Early post-operative rising.", "content": "Early post-operative rising.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008774"}
{"pmid": "21008776", "title": "Sixty years ago and after.", "content": "Sixty years ago and after.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008776"}
{"pmid": "21008775", "title": "Dissecting aneurysm of the aorta.", "content": "Dissecting aneurysm of the aorta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008775"}
{"pmid": "21008802", "title": "AMA Council busy developing National Medical Plan.", "content": "AMA Council busy developing National Medical Plan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008802"}
{"pmid": "21008803", "title": "CONSIDERING a specialty?", "content": "CONSIDERING a specialty?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008803"}
{"pmid": "21008804", "title": "Hawley would expand plans providing private medical care for vets.", "content": "Hawley would expand plans providing private medical care for vets.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008804"}
{"pmid": "21008805", "title": "S. 1606.", "content": "S. 1606.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008805"}
{"pmid": "21008806", "title": "A national health congress.", "content": "A national health congress.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008806"}
{"pmid": "21008807", "title": "Sigerist sees Kaiser Plan, Soviet system parts of same pattern.", "content": "Sigerist sees Kaiser Plan, Soviet system parts of same pattern.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008807"}
{"pmid": "21008808", "title": "How to assure health legislation that will benefit the people.", "content": "How to assure health legislation that will benefit the people.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008808"}
{"pmid": "21008809", "title": "ALTMEYER tells medical society officers only Federal program can succeed.", "content": "ALTMEYER tells medical society officers only Federal program can succeed.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008809"}
{"pmid": "21008810", "title": "Patent ductus arteriosus.", "content": "Patent ductus arteriosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008810"}
{"pmid": "21008811", "title": "Surgical treatment of patent ductus arteriosus.", "content": "Surgical treatment of patent ductus arteriosus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008811"}
{"pmid": "21008812", "title": "Hypersensitivity to horse serum.", "content": "Hypersensitivity to horse serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008812"}
{"pmid": "21008813", "title": "A report of the treatment of seven cases of granuloma venereum with penicillin.", "content": "A report of the treatment of seven cases of granuloma venereum with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008813"}
{"pmid": "21008814", "title": "The treatment of furunculosis.", "content": "The treatment of furunculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008814"}
{"pmid": "21008815", "title": "An epidemic of diarrhoea caused by a new strain of the Salmonella group.", "content": "An epidemic of diarrhoea caused by a new strain of the Salmonella group.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008815"}
{"pmid": "21008817", "title": "The evolution of the Huhner test.", "content": "The evolution of the Huhner test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008817"}
{"pmid": "21008816", "title": "Experiences, dangers and sequelae of sulphonamide administration.", "content": "Experiences, dangers and sequelae of sulphonamide administration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008816"}
{"pmid": "21008818", "title": "The frigid wife.", "content": "The frigid wife.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008818"}
{"pmid": "21008819", "title": "Evolution of plastic surgery.", "content": "Evolution of plastic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008819"}
{"pmid": "21008820", "title": "Generalized insulin allergy; preliminary report.", "content": "Generalized insulin allergy; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008820"}
{"pmid": "21008821", "title": "PREVENTIVE medicine throughout the life span; geriatrics.", "content": "PREVENTIVE medicine throughout the life span; geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008821"}
{"pmid": "21008822", "title": "History of women in medicine.", "content": "History of women in medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008822"}
{"pmid": "21008823", "title": "Tropical and subtropical diseases in discharged service men.", "content": "Tropical and subtropical diseases in discharged service men.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008823"}
{"pmid": "21008824", "title": "MEMORANDUM on the teaching of tuberculosis to medical students.", "content": "MEMORANDUM on the teaching of tuberculosis to medical students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008824"}
{"pmid": "21008825", "title": "Amebiasis.", "content": "Amebiasis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008825"}
{"pmid": "21008826", "title": "Acute infectious gingivostomatitis in children.", "content": "Acute infectious gingivostomatitis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008826"}
{"pmid": "21008828", "title": "Unusual case of appendicitis; case report.", "content": "Unusual case of appendicitis; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008828"}
{"pmid": "21008827", "title": "Addison's disease.", "content": "Addison's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008827"}
{"pmid": "21008829", "title": "Medical problems of menstruation.", "content": "Medical problems of menstruation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008829"}
{"pmid": "21008830", "title": "Rehabilitation of psychiatric war casualties.", "content": "Rehabilitation of psychiatric war casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008830"}
{"pmid": "21008831", "title": "Important facts regarding hair.", "content": "Important facts regarding hair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008831"}
{"pmid": "21008832", "title": "Accent on prescriptions.", "content": "Accent on prescriptions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008832"}
{"pmid": "21008833", "title": "Jaundice; a method of deciding where surgical treatment should supplement medical care.", "content": "Jaundice; a method of deciding where surgical treatment should supplement medical care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008833"}
{"pmid": "21008834", "title": "Cystectomy for carcinoma of the bladder.", "content": "Cystectomy for carcinoma of the bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008834"}
{"pmid": "21008835", "title": "The more recent approaches to allergy.", "content": "The more recent approaches to allergy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008835"}
{"pmid": "21008836", "title": "The management of occipito-posterior positions.", "content": "The management of occipito-posterior positions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008836"}
{"pmid": "21008838", "title": "Carcinoma of the esophagus.", "content": "Carcinoma of the esophagus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008838"}
{"pmid": "21008837", "title": "Adrenal hemorrhage in the newborn.", "content": "Adrenal hemorrhage in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008837"}
{"pmid": "21008839", "title": "Osteomyelitis of the lumbar vertebrae.", "content": "Osteomyelitis of the lumbar vertebrae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008839"}
{"pmid": "21008840", "title": "Putrid empyema.", "content": "Putrid empyema.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008840"}
{"pmid": "21008841", "title": "The early diagnosis of minimal pulmonary tuberculosis.", "content": "The early diagnosis of minimal pulmonary tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008841"}
{"pmid": "21008842", "title": "Pentothal sodium anesthesia in neurologic surgery.", "content": "Pentothal sodium anesthesia in neurologic surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008842"}
{"pmid": "21008843", "title": "Agranulocytosis following mapharsen therapy; a report of two cases treated with penicillin.", "content": "Agranulocytosis following mapharsen therapy; a report of two cases treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008843"}
{"pmid": "21008844", "title": "Some clinical aspects of social medicine.", "content": "Some clinical aspects of social medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008844"}
{"pmid": "21008845", "title": "Normal laboratory values.", "content": "Normal laboratory values.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008845"}
{"pmid": "21008846", "title": "Papillary adenocarcinoma of head of pancreas, with metastases to common bile duct and lung.", "content": "Papillary adenocarcinoma of head of pancreas, with metastases to common bile duct and lung.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008846"}
{"pmid": "21008847", "title": "METHODS of paying physicians under medical-care plans.", "content": "METHODS of paying physicians under medical-care plans.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008847"}
{"pmid": "21008848", "title": "A suggested plan for state-wide voluntary health insurance.", "content": "A suggested plan for state-wide voluntary health insurance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008848"}
{"pmid": "21008849", "title": "The practical use of digitals.", "content": "The practical use of digitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008849"}
{"pmid": "21008850", "title": "Meningitis due to Hemophilus influenzae; report of case treated with sulfadiazine, streptomycin, and antiserum, with recovery.", "content": "Meningitis due to Hemophilus influenzae; report of case treated with sulfadiazine, streptomycin, and antiserum, with recovery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008850"}
{"pmid": "21008851", "title": "Cervical ribs and the scalenus anticus syndrome; a review of the literature and report of a case.", "content": "Cervical ribs and the scalenus anticus syndrome; a review of the literature and report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008851"}
{"pmid": "21008852", "title": "The antimycotic effect of diethylstilbestrol.", "content": "The antimycotic effect of diethylstilbestrol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008852"}
{"pmid": "21008853", "title": "The story of yellow fever.", "content": "The story of yellow fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008853"}
{"pmid": "21008854", "title": "Recent advances in knowledge of the Rh blood factors, with special reference to the clinical applications.", "content": "Recent advances in knowledge of the Rh blood factors, with special reference to the clinical applications.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008854"}
{"pmid": "21008855", "title": "ANTIGENS in biological therapy.", "content": "ANTIGENS in biological therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008855"}
{"pmid": "21008856", "title": "HELMINTHIASIS.", "content": "HELMINTHIASIS.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008856"}
{"pmid": "21008858", "title": "BARBITURATE intoxication.", "content": "BARBITURATE intoxication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008858"}
{"pmid": "21008857", "title": "AMINO acids; a new field of usefulness.", "content": "AMINO acids; a new field of usefulness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008857"}
{"pmid": "21008859", "title": "The scope of neurosurgery.", "content": "The scope of neurosurgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008859"}
{"pmid": "21008860", "title": "Modern views on the etiology and treatment of acute anterior poliomyelitis.", "content": "Modern views on the etiology and treatment of acute anterior poliomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008860"}
{"pmid": "21008861", "title": "Peripheral neuritis (polyneuritis, mutiple symmetrical peripheral neuritis).", "content": "Peripheral neuritis (polyneuritis, mutiple symmetrical peripheral neuritis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008861"}
{"pmid": "21008862", "title": "Modern views on concussion.", "content": "Modern views on concussion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008862"}
{"pmid": "21008863", "title": "Subarachnoid haemorrhage.", "content": "Subarachnoid haemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008863"}
{"pmid": "21008864", "title": "The acute respiratory catarrhs.", "content": "The acute respiratory catarrhs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008864"}
{"pmid": "21008865", "title": "Posture.", "content": "Posture.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008865"}
{"pmid": "21008866", "title": "Pregnancy and tuberculosis.", "content": "Pregnancy and tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008866"}
{"pmid": "21008867", "title": "The names of new drugs.", "content": "The names of new drugs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008867"}
{"pmid": "21008868", "title": "The early recognition of disease; heart disease.", "content": "The early recognition of disease; heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008868"}
{"pmid": "21008871", "title": "Fish and rheumatism.", "content": "Fish and rheumatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008871"}
{"pmid": "21008869", "title": "Indications for obstetric forceps.", "content": "Indications for obstetric forceps.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008869"}
{"pmid": "21008870", "title": "The choice of sulphonamides.", "content": "The choice of sulphonamides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008870"}
{"pmid": "21008879", "title": "IRRITACION y tensión premenstrual y hormonas del cuerpo lúteo.", "content": "IRRITACION y tensión premenstrual y hormonas del cuerpo lúteo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008879"}
{"pmid": "21008887", "title": "ESTERILIDAD.", "content": "ESTERILIDAD.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21008887"}
{"pmid": "21009002", "title": "The evaluation of palpitation.", "content": "The evaluation of palpitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009002"}
{"pmid": "21009004", "title": "Lymphosarcoma, with primary manifestations in the gastro-intestinal tract; report of seven cases studied roentgenologically.", "content": "Lymphosarcoma, with primary manifestations in the gastro-intestinal tract; report of seven cases studied roentgenologically.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009004"}
{"pmid": "21009003", "title": "Human encephalitis due to the Western equine encephalomyelitis virus.", "content": "Human encephalitis due to the Western equine encephalomyelitis virus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009003"}
{"pmid": "21009005", "title": "Physiologic approach to the problem of oophorectomy.", "content": "Physiologic approach to the problem of oophorectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009005"}
{"pmid": "21009006", "title": "Parathyroid adenoma of the anterior mediastinum.", "content": "Parathyroid adenoma of the anterior mediastinum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009006"}
{"pmid": "21009007", "title": "Acute meningococcemia without meningitis; report of a case.", "content": "Acute meningococcemia without meningitis; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009007"}
{"pmid": "21009008", "title": "Vital statistics in public health.", "content": "Vital statistics in public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009008"}
{"pmid": "21009009", "title": "Governing a health unit; organization, activities, and plans for future housing.", "content": "Governing a health unit; organization, activities, and plans for future housing.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009009"}
{"pmid": "21009037", "title": "Prostatic carcinoma treated by orchectomy; a third report based on seventy-five cases observed for at least thirty-five months following orchectomy.", "content": "Prostatic carcinoma treated by orchectomy; a third report based on seventy-five cases observed for at least thirty-five months following orchectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009037"}
{"pmid": "21009038", "title": "Bronchial-Asthma.", "content": "Bronchial-Asthma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009038"}
{"pmid": "21009041", "title": "Management of thrombophlebitis.", "content": "Management of thrombophlebitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009041"}
{"pmid": "21009042", "title": "A note on the occurrence of silicosis in bituminous coal miners.", "content": "A note on the occurrence of silicosis in bituminous coal miners.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009042"}
{"pmid": "21009043", "title": "Pitfalls in localizing intestinal obstruction with the scout film; case report.", "content": "Pitfalls in localizing intestinal obstruction with the scout film; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009043"}
{"pmid": "21009044", "title": "Occupational therapy and the ageing person.", "content": "Occupational therapy and the ageing person.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009044"}
{"pmid": "21009045", "title": "Leukemia in naval personnel.", "content": "Leukemia in naval personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009045"}
{"pmid": "21009046", "title": "Early recognition and treatment of vascular injuries.", "content": "Early recognition and treatment of vascular injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009046"}
{"pmid": "21009047", "title": "Early treatment of orthopedic casualties on a hospital ship.", "content": "Early treatment of orthopedic casualties on a hospital ship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009047"}
{"pmid": "21009048", "title": "Covering the guillotined stump.", "content": "Covering the guillotined stump.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009048"}
{"pmid": "21009049", "title": "Anesthesia on a hospital ship.", "content": "Anesthesia on a hospital ship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009049"}
{"pmid": "21009051", "title": "Perforating wounds of the kidney.", "content": "Perforating wounds of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009051"}
{"pmid": "21009050", "title": "Medical problems of an internist on a hospital ship.", "content": "Medical problems of an internist on a hospital ship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009050"}
{"pmid": "21009052", "title": "Punctate cerebral hemorrhage following thoracic trauma.", "content": "Punctate cerebral hemorrhage following thoracic trauma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009052"}
{"pmid": "21009053", "title": "Injuries of the face and neck in war casualties.", "content": "Injuries of the face and neck in war casualties.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009053"}
{"pmid": "21009054", "title": "Eye injuries in war casualties aboard a hospital ship.", "content": "Eye injuries in war casualties aboard a hospital ship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009054"}
{"pmid": "21009055", "title": "Embarkation and disembarkation of hospital ship patients.", "content": "Embarkation and disembarkation of hospital ship patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009055"}
{"pmid": "21009056", "title": "Pneumoroentgenarthrography as a diagnostic aid in internal derangements of the knee.", "content": "Pneumoroentgenarthrography as a diagnostic aid in internal derangements of the knee.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009056"}
{"pmid": "21009057", "title": "Effect of bite-wing roentgenograms on Navy dental examination findings.", "content": "Effect of bite-wing roentgenograms on Navy dental examination findings.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009057"}
{"pmid": "21009058", "title": "Seventy-eight hundred scarlet fever patients.", "content": "Seventy-eight hundred scarlet fever patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009058"}
{"pmid": "21009059", "title": "Convalescent serum and pooled plasma in communicable diseases.", "content": "Convalescent serum and pooled plasma in communicable diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009059"}
{"pmid": "21009060", "title": "Penicillin in intrapleural infection.", "content": "Penicillin in intrapleural infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009060"}
{"pmid": "21009061", "title": "Dermoid cyst of rectovaginal septum.", "content": "Dermoid cyst of rectovaginal septum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009061"}
{"pmid": "21009062", "title": "Poisonous snake (habu) bites.", "content": "Poisonous snake (habu) bites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009062"}
{"pmid": "21009063", "title": "Acute appendicitis in amebic dysentery; report of a case.", "content": "Acute appendicitis in amebic dysentery; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009063"}
{"pmid": "21009064", "title": "Alveolar resorption due to occupational trauma; report of a case.", "content": "Alveolar resorption due to occupational trauma; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009064"}
{"pmid": "21009066", "title": "Double gallbladder; report of a case.", "content": "Double gallbladder; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009066"}
{"pmid": "21009065", "title": "Simple management of open bite; report of a case.", "content": "Simple management of open bite; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009065"}
{"pmid": "21009067", "title": "Casualty handling on an attack transport.", "content": "Casualty handling on an attack transport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009067"}
{"pmid": "21009068", "title": "Small type skeletal traction apparatus.", "content": "Small type skeletal traction apparatus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009068"}
{"pmid": "21009069", "title": "New type surgical hand drill.", "content": "New type surgical hand drill.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009069"}
{"pmid": "21009071", "title": "Genes and the chemistry of the organism.", "content": "Genes and the chemistry of the organism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009071"}
{"pmid": "21009073", "title": "Education and the National Science Foundation.", "content": "Education and the National Science Foundation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009073"}
{"pmid": "21009070", "title": "Toxic effects of arsenical compounds as employed in the treatment of diseases in the United States Navy, 1944.", "content": "Toxic effects of arsenical compounds as employed in the treatment of diseases in the United States Navy, 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009070"}
{"pmid": "21009074", "title": "The national roster and the Science Foundation.", "content": "The national roster and the Science Foundation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009074"}
{"pmid": "21009072", "title": "The physical structure and biological action of nerve cells; with some references to the problems of human flight.", "content": "The physical structure and biological action of nerve cells; with some references to the problems of human flight.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009072"}
{"pmid": "21009075", "title": "The charter and challenge of UNESCO.", "content": "The charter and challenge of UNESCO.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009075"}
{"pmid": "21009084", "title": "Scientific training.", "content": "Scientific training.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009084"}
{"pmid": "21009077", "title": "The Argentine curly top of sugar beet.", "content": "The Argentine curly top of sugar beet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009077"}
{"pmid": "21009085", "title": "The anemia associated with chronic infection.", "content": "The anemia associated with chronic infection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009085"}
{"pmid": "21009076", "title": "Influence of light and temperature on sugar cane and Erianthus.", "content": "Influence of light and temperature on sugar cane and Erianthus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009076"}
{"pmid": "21009086", "title": "An observation of the red cell content of the blood of the thoroughbred horse.", "content": "An observation of the red cell content of the blood of the thoroughbred horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009086"}
{"pmid": "21009087", "title": "Fur and feathers; a response to falling temperature.", "content": "Fur and feathers; a response to falling temperature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009087"}
{"pmid": "21009088", "title": "Semi-continuous tap-water aerator.", "content": "Semi-continuous tap-water aerator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009088"}
{"pmid": "21009089", "title": "Prozones and blocking effect in normal iso- and hetero-agglutination with cord sera.", "content": "Prozones and blocking effect in normal iso- and hetero-agglutination with cord sera.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009089"}
{"pmid": "21009090", "title": "Research on phenothiazine as an anthelmintic.", "content": "Research on phenothiazine as an anthelmintic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009090"}
{"pmid": "21009091", "title": "Early man in Oregon; stratigraphic evidence.", "content": "Early man in Oregon; stratigraphic evidence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009091"}
{"pmid": "21009092", "title": "Early man in Oregon; pluvial lakes and pumice.", "content": "Early man in Oregon; pluvial lakes and pumice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009092"}
{"pmid": "21009093", "title": "Gerontology comes of age.", "content": "Gerontology comes of age.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009093"}
{"pmid": "21009094", "title": "The limitation of creative years.", "content": "The limitation of creative years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009094"}
{"pmid": "21009095", "title": "The social significance of Jewish-Christian intermarriage.", "content": "The social significance of Jewish-Christian intermarriage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009095"}
{"pmid": "21009098", "title": "Innervation of the bone marrow.", "content": "Innervation of the bone marrow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009098"}
{"pmid": "21009099", "title": "The innervation of the pancreas.", "content": "The innervation of the pancreas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009099"}
{"pmid": "21009100", "title": "Capillaries and mitochondria in neurophil.", "content": "Capillaries and mitochondria in neurophil.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009100"}
{"pmid": "21009101", "title": "Neuropathological problems arising from prefrontal leucotomy.", "content": "Neuropathological problems arising from prefrontal leucotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009101"}
{"pmid": "21009102", "title": "Psychopathic personality and crime.", "content": "Psychopathic personality and crime.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009102"}
{"pmid": "21009103", "title": "Delirious disorientation: the law of the unfamiliar mistaken for the familiar.", "content": "Delirious disorientation: the law of the unfamiliar mistaken for the familiar.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009103"}
{"pmid": "21009104", "title": "Neuroses in firemen.", "content": "Neuroses in firemen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009104"}
{"pmid": "21009105", "title": "Explosive rage following head injury.", "content": "Explosive rage following head injury.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009105"}
{"pmid": "21009106", "title": "The impulsive psychopath: a clinical and electrophysiological study.", "content": "The impulsive psychopath: a clinical and electrophysiological study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009106"}
{"pmid": "21009107", "title": "The psychoneurotic spectrum and dual diagnosis.", "content": "The psychoneurotic spectrum and dual diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009107"}
{"pmid": "21009108", "title": "The Kielder experiment.", "content": "The Kielder experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009108"}
{"pmid": "21009109", "title": "A case of obsessional state of unusual content.", "content": "A case of obsessional state of unusual content.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009109"}
{"pmid": "21009110", "title": "Phantasies in evacuated children.", "content": "Phantasies in evacuated children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009110"}
{"pmid": "21009111", "title": "Depression in parkinsonism treated by prefrontal leucotomy.", "content": "Depression in parkinsonism treated by prefrontal leucotomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009111"}
{"pmid": "21009112", "title": "Two years' experience of female schizophrenics treated by insulin coma therapy.", "content": "Two years' experience of female schizophrenics treated by insulin coma therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009112"}
{"pmid": "21009113", "title": "Length of treatment in child guidance clinics.", "content": "Length of treatment in child guidance clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009113"}
{"pmid": "21009114", "title": "A syndrome associated with left hand paralysis of central origin.", "content": "A syndrome associated with left hand paralysis of central origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009114"}
{"pmid": "21009115", "title": "The Starcross reading board; a dynamic aid to reading.", "content": "The Starcross reading board; a dynamic aid to reading.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009115"}
{"pmid": "21009116", "title": "Hemiatrophy of the body in adult life.", "content": "Hemiatrophy of the body in adult life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009116"}
{"pmid": "21009117", "title": "Unusual involvement of the nervous system in generalized lymphoblastoma.", "content": "Unusual involvement of the nervous system in generalized lymphoblastoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009117"}
{"pmid": "21009118", "title": "Is the epileptic a safe motor vehicle driver?; with some remarks relative to the clinical application of the EEG.", "content": "Is the epileptic a safe motor vehicle driver?; with some remarks relative to the clinical application of the EEG.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009118"}
{"pmid": "21009119", "title": "Study of a case of pseudo deafmuteness (psychic deafness).", "content": "Study of a case of pseudo deafmuteness (psychic deafness).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009119"}
{"pmid": "21009120", "title": "The relationship of the vegetative nervous system to angina pectoris (abdominalis).", "content": "The relationship of the vegetative nervous system to angina pectoris (abdominalis).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009120"}
{"pmid": "21009121", "title": "Classification of anxiety reactions (anxiety states).", "content": "Classification of anxiety reactions (anxiety states).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009121"}
{"pmid": "21009122", "title": "Mènière's syndrome; a comparison of the results of medical and surgical treatment.", "content": "Mènière's syndrome; a comparison of the results of medical and surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009122"}
{"pmid": "21009123", "title": "The clinical diagnosis of central sympathetic disturbances by means of pupillography.", "content": "The clinical diagnosis of central sympathetic disturbances by means of pupillography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009123"}
{"pmid": "21009124", "title": "Management of the alcoholic by the general practitioner.", "content": "Management of the alcoholic by the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009124"}
{"pmid": "21009125", "title": "Mental hospital patients are older.", "content": "Mental hospital patients are older.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009125"}
{"pmid": "21009126", "title": "What you, the layman, can do about mental hygiene.", "content": "What you, the layman, can do about mental hygiene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009126"}
{"pmid": "21009131", "title": "American race relations and the caste system.", "content": "American race relations and the caste system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009131"}
{"pmid": "21009132", "title": "Dug-out psychiatry.", "content": "Dug-out psychiatry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009132"}
{"pmid": "21009135", "title": "German words, German personality and Protestantism.", "content": "German words, German personality and Protestantism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009135"}
{"pmid": "21009133", "title": "Psychiatric observations in Okinawa Shima.", "content": "Psychiatric observations in Okinawa Shima.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009133"}
{"pmid": "21009134", "title": "A psychiatric hospital in military government.", "content": "A psychiatric hospital in military government.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009134"}
{"pmid": "21009136", "title": "Subjective definitions of the Rorschach test situation and their effect on test performance.", "content": "Subjective definitions of the Rorschach test situation and their effect on test performance.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009136"}
{"pmid": "21009138", "title": "FAMILY life program.", "content": "FAMILY life program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009138"}
{"pmid": "21009137", "title": "Personality development of the dinaric warriors.", "content": "Personality development of the dinaric warriors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009137"}
{"pmid": "21009139", "title": "Should mother and baby room together?", "content": "Should mother and baby room together?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009139"}
{"pmid": "21009140", "title": "POSTURE fundamentals illustrated; the patient.", "content": "POSTURE fundamentals illustrated; the patient.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009140"}
{"pmid": "21009141", "title": "Tidal drainage of the urinary bladder.", "content": "Tidal drainage of the urinary bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009141"}
{"pmid": "21009142", "title": "Corneal transplantation.", "content": "Corneal transplantation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009142"}
{"pmid": "21009145", "title": "Nursing care of psychoneurotic patients.", "content": "Nursing care of psychoneurotic patients.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009145"}
{"pmid": "21009143", "title": "Corneal transplantation and nursing care.", "content": "Corneal transplantation and nursing care.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009143"}
{"pmid": "21009144", "title": "It's your career, why not plan for it?", "content": "It's your career, why not plan for it?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009144"}
{"pmid": "21009146", "title": "Marine hospitals; an opportunity for nurses.", "content": "Marine hospitals; an opportunity for nurses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009146"}
{"pmid": "21009147", "title": "Faculty organization.", "content": "Faculty organization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009147"}
{"pmid": "21009149", "title": "Standard illuminants in relation to color-testing procedures.", "content": "Standard illuminants in relation to color-testing procedures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009149"}
{"pmid": "21009150", "title": "Senile hyaline scleral plaques.", "content": "Senile hyaline scleral plaques.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009150"}
{"pmid": "21009151", "title": "Traumatic iridodialysis; its surgical correction.", "content": "Traumatic iridodialysis; its surgical correction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009151"}
{"pmid": "21009152", "title": "Tests for detection and analysis of color blindness; an evaluation of the Ishihara test.", "content": "Tests for detection and analysis of color blindness; an evaluation of the Ishihara test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009152"}
{"pmid": "21009148", "title": "Effect of local anesthetics on cell division and migration following thermal burns of cornea.", "content": "Effect of local anesthetics on cell division and migration following thermal burns of cornea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009148"}
{"pmid": "21009155", "title": "An unusual case of Hodgkin's disease; second report.", "content": "An unusual case of Hodgkin's disease; second report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009155"}
{"pmid": "21009153", "title": "Stereoscopic sensitivity in the space eikonometer.", "content": "Stereoscopic sensitivity in the space eikonometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009153"}
{"pmid": "21009154", "title": "Clinical differentiation of emboli in the retinal arteries from endarteritis.", "content": "Clinical differentiation of emboli in the retinal arteries from endarteritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009154"}
{"pmid": "21009156", "title": "Cardinal points in the static and in the dynamic eye.", "content": "Cardinal points in the static and in the dynamic eye.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009156"}
{"pmid": "21009158", "title": "Ocular changes associated with arachnodactyly.", "content": "Ocular changes associated with arachnodactyly.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009158"}
{"pmid": "21009157", "title": "Retinal vascular micrometry and essential hypertension.", "content": "Retinal vascular micrometry and essential hypertension.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009157"}
{"pmid": "21009159", "title": "Traumatic staining of the conjunctiva with indelible lead; report of a case.", "content": "Traumatic staining of the conjunctiva with indelible lead; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009159"}
{"pmid": "21009160", "title": "Discission of the lens in high myopia.", "content": "Discission of the lens in high myopia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009160"}
{"pmid": "21009162", "title": "Inadequacies of functional hearing tests for so-called nerve deafness.", "content": "Inadequacies of functional hearing tests for so-called nerve deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009162"}
{"pmid": "21009161", "title": "The Lempert endaural mastoidectomy and the Lempert fenestration operation for deafness.", "content": "The Lempert endaural mastoidectomy and the Lempert fenestration operation for deafness.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009161"}
{"pmid": "21009163", "title": "Chronic primary glaucoma; diagnostic signs and symptoms, and medical treatment.", "content": "Chronic primary glaucoma; diagnostic signs and symptoms, and medical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009163"}
{"pmid": "21009164", "title": "Preoperative and postoperative treatment at Greens' Eye Hospital.", "content": "Preoperative and postoperative treatment at Greens' Eye Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009164"}
{"pmid": "21009165", "title": "Energy distribution of diffraction gratings as a function of groove form.", "content": "Energy distribution of diffraction gratings as a function of groove form.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009165"}
{"pmid": "21009166", "title": "The paraxial differential transfer coefficients of a lens system.", "content": "The paraxial differential transfer coefficients of a lens system.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009166"}
{"pmid": "21009167", "title": "Theory of the space-eikonometer.", "content": "Theory of the space-eikonometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009167"}
{"pmid": "21009168", "title": "Modified chromatic value color space.", "content": "Modified chromatic value color space.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009168"}
{"pmid": "21009169", "title": "A photoelectric refractometer.", "content": "A photoelectric refractometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009169"}
{"pmid": "21009170", "title": "Two bilateral spectrograph slits.", "content": "Two bilateral spectrograph slits.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009170"}
{"pmid": "21009173", "title": "Pharyngo-esophageal diverticulum.", "content": "Pharyngo-esophageal diverticulum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009173"}
{"pmid": "21009171", "title": "Spectrographic determination of calcium in microbiological culture media.", "content": "Spectrographic determination of calcium in microbiological culture media.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009171"}
{"pmid": "21009172", "title": "Plastic surgery in congenital deformities about the face.", "content": "Plastic surgery in congenital deformities about the face.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009172"}
{"pmid": "21009174", "title": "The primary cause of glaucoma.", "content": "The primary cause of glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009174"}
{"pmid": "21009175", "title": "Hearing aids for deaf children.", "content": "Hearing aids for deaf children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009175"}
{"pmid": "21009176", "title": "Hearing aid service for children.", "content": "Hearing aid service for children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009176"}
{"pmid": "21009177", "title": "NEW hearing aid carrier.", "content": "NEW hearing aid carrier.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009177"}
{"pmid": "21009178", "title": "Paget's disease of the nipple; with special reference to the changes in the ducts.", "content": "Paget's disease of the nipple; with special reference to the changes in the ducts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009178"}
{"pmid": "21009179", "title": "A chronic granulomatous disease of swine with striking resemblance to Hodgkin's disease.", "content": "A chronic granulomatous disease of swine with striking resemblance to Hodgkin's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009179"}
{"pmid": "21009180", "title": "Fat embolism.", "content": "Fat embolism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009180"}
{"pmid": "21009181", "title": "Growth of the rickettsiae of Tsutsugamushi fever on the chorioallantoic membrane of the developing chick embryo.", "content": "Growth of the rickettsiae of Tsutsugamushi fever on the chorioallantoic membrane of the developing chick embryo.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009181"}
{"pmid": "21009182", "title": "Lesions of skeletal muscles in rheumatoid arthritis; nodular polymyositis.", "content": "Lesions of skeletal muscles in rheumatoid arthritis; nodular polymyositis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009182"}
{"pmid": "21009183", "title": "Hydrogen sulfide poisoning; report of two cases, one with fatal outcome, from associated mechanical asphyxia.", "content": "Hydrogen sulfide poisoning; report of two cases, one with fatal outcome, from associated mechanical asphyxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009183"}
{"pmid": "21009184", "title": "Hyperplasia of the adrenal cortex associated with bilateral testicular tumors.", "content": "Hyperplasia of the adrenal cortex associated with bilateral testicular tumors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009184"}
{"pmid": "21009185", "title": "Studies on ameboid motion and secretion of motor endplates; experimental pathology of the secretory mechanism of motor end-plates in thermal shock.", "content": "Studies on ameboid motion and secretion of motor endplates; experimental pathology of the secretory mechanism of motor end-plates in thermal shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009185"}
{"pmid": "21009186", "title": "Infectivity of the primary complex of tuberculosis of childhood.", "content": "Infectivity of the primary complex of tuberculosis of childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009186"}
{"pmid": "21009187", "title": "Studies on the streptococci (entercococci) of Lancefield group D; recovery of Lancefield group D streptococoi from antemortem and postmortem cultures from infants and young children.", "content": "Studies on the streptococci (entercococci) of Lancefield group D; recovery of Lancefield group D streptococoi from antemortem and postmortem cultures from infants and young children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009187"}
{"pmid": "21009188", "title": "Nutrition studies on children living at home; calory intakes on the basis of age from one through ten years.", "content": "Nutrition studies on children living at home; calory intakes on the basis of age from one through ten years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009188"}
{"pmid": "21009189", "title": "Basal metabolism of eight nursery school children determined at three month intervals.", "content": "Basal metabolism of eight nursery school children determined at three month intervals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009189"}
{"pmid": "21009190", "title": "Pyopneumothorax in a premature baby successfully treated with penicillin.", "content": "Pyopneumothorax in a premature baby successfully treated with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009190"}
{"pmid": "21009191", "title": "Histoplasmosis in children; review of the literature, with report of a case.", "content": "Histoplasmosis in children; review of the literature, with report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009191"}
{"pmid": "21009192", "title": "Mortality trends in the newborn.", "content": "Mortality trends in the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009192"}
{"pmid": "21009193", "title": "Cold agglutinins as a cause of hemolysis in erythroblatosis neonatorum.", "content": "Cold agglutinins as a cause of hemolysis in erythroblatosis neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009193"}
{"pmid": "21009194", "title": "Congenital intestinal obstruction in the newborn; report of three cases with successful results of surgical treatment.", "content": "Congenital intestinal obstruction in the newborn; report of three cases with successful results of surgical treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009194"}
{"pmid": "21009195", "title": "Congenital morphinism; report of a case.", "content": "Congenital morphinism; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009195"}
{"pmid": "21009196", "title": "Recurrent or suppurative parotitis.", "content": "Recurrent or suppurative parotitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009196"}
{"pmid": "21009197", "title": "Tuberculosis of bone.", "content": "Tuberculosis of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009197"}
{"pmid": "21009198", "title": "Some aspects of infantile pathology in the cities of the Western Netherlands during the time of the blockade.", "content": "Some aspects of infantile pathology in the cities of the Western Netherlands during the time of the blockade.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009198"}
{"pmid": "21009211", "title": "The erythrocyte sedimentation rate and its applications to pediatrics.", "content": "The erythrocyte sedimentation rate and its applications to pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009211"}
{"pmid": "21009212", "title": "Psychometrics in pediatrics.", "content": "Psychometrics in pediatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009212"}
{"pmid": "21009213", "title": "Splenic neutropenia.", "content": "Splenic neutropenia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009213"}
{"pmid": "21009214", "title": "Hirschsprung's disease.", "content": "Hirschsprung's disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009214"}
{"pmid": "21009215", "title": "Lymphoblastoma?", "content": "Lymphoblastoma?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009215"}
{"pmid": "21009216", "title": "Tuberculosis in children.", "content": "Tuberculosis in children.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009216"}
{"pmid": "21009217", "title": "Shall we tuberculin test school children?", "content": "Shall we tuberculin test school children?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009217"}
{"pmid": "21009218", "title": "Striving for completeness in a school health program.", "content": "Striving for completeness in a school health program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009218"}
{"pmid": "21009219", "title": "School health education.", "content": "School health education.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009219"}
{"pmid": "21009228", "title": "THERAPEUTIC use of curare.", "content": "THERAPEUTIC use of curare.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009228"}
{"pmid": "21009226", "title": "DESOXYEPHEDRINE; its chemistry and uses.", "content": "DESOXYEPHEDRINE; its chemistry and uses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009226"}
{"pmid": "21009227", "title": "Hydrophilic ointment.", "content": "Hydrophilic ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009227"}
{"pmid": "21009229", "title": "What about our pharmacy boards?", "content": "What about our pharmacy boards?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009229"}
{"pmid": "21009230", "title": "Dispensing in State institutions.", "content": "Dispensing in State institutions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009230"}
{"pmid": "21009231", "title": "ACETANILID powder, compound.", "content": "ACETANILID powder, compound.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009231"}
{"pmid": "21009239", "title": "Penicillin preparations.", "content": "Penicillin preparations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009239"}
{"pmid": "21009241", "title": "Dust in the home and factory.", "content": "Dust in the home and factory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009241"}
{"pmid": "21009240", "title": "A penicillin distributing centre in operation.", "content": "A penicillin distributing centre in operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009240"}
{"pmid": "21009242", "title": "Shingles.", "content": "Shingles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009242"}
{"pmid": "21009232", "title": "ALUMINUM acetate solution.", "content": "ALUMINUM acetate solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009232"}
{"pmid": "21009243", "title": "A note on abrasions and other minor injuries.", "content": "A note on abrasions and other minor injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009243"}
{"pmid": "21009234", "title": "CALCIUM GLYCEROPHOSPHATE.", "content": "CALCIUM GLYCEROPHOSPHATE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009234"}
{"pmid": "21009244", "title": "What is the N.A.P.T.?", "content": "What is the N.A.P.T.?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009244"}
{"pmid": "21009233", "title": "BEEF extract.", "content": "BEEF extract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009233"}
{"pmid": "21009236", "title": "IODINE ointment.", "content": "IODINE ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009236"}
{"pmid": "21009235", "title": "FERRIC glycerophosphate.", "content": "FERRIC glycerophosphate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009235"}
{"pmid": "21009246", "title": "MENOPAUSE.", "content": "MENOPAUSE.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009246"}
{"pmid": "21009245", "title": "ORAL administration of penicillin.", "content": "ORAL administration of penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009245"}
{"pmid": "21009247", "title": "The influence of sodium lauryl sulfate on the biologic response to the gonadotropins and to insulin.", "content": "The influence of sodium lauryl sulfate on the biologic response to the gonadotropins and to insulin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009247"}
{"pmid": "21009249", "title": "Respiratory flow in Mustelus.", "content": "Respiratory flow in Mustelus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009249"}
{"pmid": "21009248", "title": "Vitamin deficiency and overdosage and the resistance of rats to lowered barometric pressures.", "content": "Vitamin deficiency and overdosage and the resistance of rats to lowered barometric pressures.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009248"}
{"pmid": "21009250", "title": "The number and relative concentrations of protein constituents of canine pancreatic juice as determined by electrophoresis.", "content": "The number and relative concentrations of protein constituents of canine pancreatic juice as determined by electrophoresis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009250"}
{"pmid": "21009253", "title": "Changes in the blood during chronic and acute dehydration.", "content": "Changes in the blood during chronic and acute dehydration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009253"}
{"pmid": "21009251", "title": "The action of acetylcholine and epinephrine on the turtle ventricle.", "content": "The action of acetylcholine and epinephrine on the turtle ventricle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009251"}
{"pmid": "21009254", "title": "The effect of protein and fat content of the diet upon the toxicity of benzene for rats.", "content": "The effect of protein and fat content of the diet upon the toxicity of benzene for rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009254"}
{"pmid": "21009252", "title": "The effect of sodium and chloride salts in preventing the shocklike state following venous occlusion of a limb in the dog.", "content": "The effect of sodium and chloride salts in preventing the shocklike state following venous occlusion of a limb in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009252"}
{"pmid": "21009256", "title": "The effect of acetylcholine on the atropinized, denervated heart.", "content": "The effect of acetylcholine on the atropinized, denervated heart.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009256"}
{"pmid": "21009258", "title": "Alterations in the properties of dog hepatic bile with increasing age of the chronic biliary fistula.", "content": "Alterations in the properties of dog hepatic bile with increasing age of the chronic biliary fistula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009258"}
{"pmid": "21009255", "title": "The increased susceptibility of protein-deficient dogs to benzene poisoning.", "content": "The increased susceptibility of protein-deficient dogs to benzene poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009255"}
{"pmid": "21009257", "title": "Consideration of the mechanism of neutralization of endogenous gonadotrophic hormone of the rat by antigonadotrophic serum.", "content": "Consideration of the mechanism of neutralization of endogenous gonadotrophic hormone of the rat by antigonadotrophic serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009257"}
{"pmid": "21009259", "title": "Age, sex, carbohydrate, adrenal cortex and other factors in anoxia.", "content": "Age, sex, carbohydrate, adrenal cortex and other factors in anoxia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009259"}
{"pmid": "21009260", "title": "The survival of non-adrenalectomized rats in burn shock with and without adrenal cortical hormone treatment.", "content": "The survival of non-adrenalectomized rats in burn shock with and without adrenal cortical hormone treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009260"}
{"pmid": "21009262", "title": "The effect of exposure to oxygen at high pressure upon the tonus and respiration of pyloric muscle from the rabbit.", "content": "The effect of exposure to oxygen at high pressure upon the tonus and respiration of pyloric muscle from the rabbit.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009262"}
{"pmid": "21009261", "title": "The changes in components A and B of prothrombin in the dog following hepatectomy.", "content": "The changes in components A and B of prothrombin in the dog following hepatectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009261"}
{"pmid": "21009263", "title": "Effect of ambient air temperature and of hand temperature on blood flow in hands.", "content": "Effect of ambient air temperature and of hand temperature on blood flow in hands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009263"}
{"pmid": "21009264", "title": "The effects of intracisternal injection of potassium phosphate on the rate and rhythm of the heart and on the blood pressure and on the respiration of the dog.", "content": "The effects of intracisternal injection of potassium phosphate on the rate and rhythm of the heart and on the blood pressure and on the respiration of the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009264"}
{"pmid": "21009266", "title": "The elimination of carbon monoxide from the human body with reference to the possible conversion of CO to CO2.", "content": "The elimination of carbon monoxide from the human body with reference to the possible conversion of CO to CO2.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009266"}
{"pmid": "21009265", "title": "The fate of CO in the body during recovery from mild carbon monoxide poisoning in man.", "content": "The fate of CO in the body during recovery from mild carbon monoxide poisoning in man.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009265"}
{"pmid": "21009267", "title": "The role of the proprioceptors in shivering.", "content": "The role of the proprioceptors in shivering.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009267"}
{"pmid": "21009272", "title": "Psychotherpay in a case of obesity.", "content": "Psychotherpay in a case of obesity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009272"}
{"pmid": "21009268", "title": "Developments in human adjustment and rehabilitation.", "content": "Developments in human adjustment and rehabilitation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009268"}
{"pmid": "21009269", "title": "Some relationships between children's symptoms of maladjustment and background factors.", "content": "Some relationships between children's symptoms of maladjustment and background factors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009269"}
{"pmid": "21009270", "title": "Diagnostic patterns on the Minnesota multiphasic personality inventory.", "content": "Diagnostic patterns on the Minnesota multiphasic personality inventory.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009270"}
{"pmid": "21009271", "title": "The discriminatory value of a test pattern in the high grade familial defective.", "content": "The discriminatory value of a test pattern in the high grade familial defective.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009271"}
{"pmid": "21009274", "title": "Directive psychotherapy; the technique of psychological palliation.", "content": "Directive psychotherapy; the technique of psychological palliation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009274"}
{"pmid": "21009273", "title": "The dynamics of non-directive psychotherapy.", "content": "The dynamics of non-directive psychotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009273"}
{"pmid": "21009275", "title": "A quick method of analyzing the similarity of profiles.", "content": "A quick method of analyzing the similarity of profiles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009275"}
{"pmid": "21009277", "title": "Clinical values of projective techniques in an Army hospital.", "content": "Clinical values of projective techniques in an Army hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009277"}
{"pmid": "21009276", "title": "Therapeutic aspects of the psychological interview.", "content": "Therapeutic aspects of the psychological interview.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009276"}
{"pmid": "21009278", "title": "Blood and blood derivatives; a new public health field.", "content": "Blood and blood derivatives; a new public health field.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009278"}
{"pmid": "21009279", "title": "Typhoid vaccine studies; the suitability of Vi antigen as an auxiliary immunogen for typhoid vaccine; progress report.", "content": "Typhoid vaccine studies; the suitability of Vi antigen as an auxiliary immunogen for typhoid vaccine; progress report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009279"}
{"pmid": "21009282", "title": "Epidemiological studies on infectious hepatitis.", "content": "Epidemiological studies on infectious hepatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009282"}
{"pmid": "21009280", "title": "Age and sex variations in the prevalence and onset of diabetes mellitus.", "content": "Age and sex variations in the prevalence and onset of diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009280"}
{"pmid": "21009281", "title": "Out break of typhoid fever with orange juice as the vehicle, illustrating the value of immunization.", "content": "Out break of typhoid fever with orange juice as the vehicle, illustrating the value of immunization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009281"}
{"pmid": "21009283", "title": "PROPOSED report on the educational qualifications of nutritionists in health agencies.", "content": "PROPOSED report on the educational qualifications of nutritionists in health agencies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009283"}
{"pmid": "21009284", "title": "Occurrence of Shigella types in the military population of the southeastern United States, 1943 and 1944.", "content": "Occurrence of Shigella types in the military population of the southeastern United States, 1943 and 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009284"}
{"pmid": "21009285", "title": "Incidence of certain biological characteristics among food poisoning staphylococci.", "content": "Incidence of certain biological characteristics among food poisoning staphylococci.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009285"}
{"pmid": "21009287", "title": "Full-time health services in Nova Scotia.", "content": "Full-time health services in Nova Scotia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009287"}
{"pmid": "21009288", "title": "Findings on re-Schick testing of Air Force personnel.", "content": "Findings on re-Schick testing of Air Force personnel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009288"}
{"pmid": "21009286", "title": "A new statement of school health policies.", "content": "A new statement of school health policies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009286"}
{"pmid": "21009290", "title": "Food poisoning due to Salmonella newport.", "content": "Food poisoning due to Salmonella newport.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009290"}
{"pmid": "21009289", "title": "Salmonellosis; a public health problem.", "content": "Salmonellosis; a public health problem.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009289"}
{"pmid": "21009291", "title": "Mapping our new frontiers of health.", "content": "Mapping our new frontiers of health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009291"}
{"pmid": "21009292", "title": "Educating food handlers.", "content": "Educating food handlers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009292"}
{"pmid": "21009293", "title": "The moral and social factors in venereal-disease control.", "content": "The moral and social factors in venereal-disease control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009293"}
{"pmid": "21009294", "title": "A method for the rapid production of citrinin.", "content": "A method for the rapid production of citrinin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009294"}
{"pmid": "21009312", "title": "Drug control.", "content": "Drug control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009312"}
{"pmid": "21009313", "title": "Dental health advisers in public health work.", "content": "Dental health advisers in public health work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009313"}
{"pmid": "21009314", "title": "The new Division of Adult Hygiene and Geriatrics.", "content": "The new Division of Adult Hygiene and Geriatrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009314"}
{"pmid": "21009316", "title": "The effect of fluorescent light on vision.", "content": "The effect of fluorescent light on vision.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009316"}
{"pmid": "21009315", "title": "The medical profession and the schools.", "content": "The medical profession and the schools.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009315"}
{"pmid": "21009317", "title": "A cycle of morphine addiction; biological and psychological studies.", "content": "A cycle of morphine addiction; biological and psychological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009317"}
{"pmid": "21009318", "title": "A cycle of morphine addiction; biological and psychological studies.", "content": "A cycle of morphine addiction; biological and psychological studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009318"}
{"pmid": "21009319", "title": "The release of antigen from certain bacteria on treatment with ether.", "content": "The release of antigen from certain bacteria on treatment with ether.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009319"}
{"pmid": "21009321", "title": "INFANT mortality declined to a record low during the war.", "content": "INFANT mortality declined to a record low during the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009321"}
{"pmid": "21009325", "title": "Energy absorption in radium therapy.", "content": "Energy absorption in radium therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009325"}
{"pmid": "21009324", "title": "The anatomy of the blood vessels of the human lung as applied to chest radiology.", "content": "The anatomy of the blood vessels of the human lung as applied to chest radiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009324"}
{"pmid": "21009326", "title": "Recent advances in investigation of the small intestine.", "content": "Recent advances in investigation of the small intestine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009326"}
{"pmid": "21009327", "title": "A feed-back amplifier for ionisation currents.", "content": "A feed-back amplifier for ionisation currents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009327"}
{"pmid": "21009329", "title": "A review of recent French literature on radiotherapy.", "content": "A review of recent French literature on radiotherapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009329"}
{"pmid": "21009328", "title": "External and internal thorium-x therapy.", "content": "External and internal thorium-x therapy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009328"}
{"pmid": "21009330", "title": "The effect of x-rays on Leishmania tropica in vitro.", "content": "The effect of x-rays on Leishmania tropica in vitro.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009330"}
{"pmid": "21009331", "title": "Eighth Stanley Melville memorial lecture; series and parallel.", "content": "Eighth Stanley Melville memorial lecture; series and parallel.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009331"}
{"pmid": "21009333", "title": "The x-ray department and the radiographer.", "content": "The x-ray department and the radiographer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009333"}
{"pmid": "21009332", "title": "X-ray set failure and the petrol electric generator.", "content": "X-ray set failure and the petrol electric generator.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009332"}
{"pmid": "21009334", "title": "Delayed internal fixation of compound battle fractures in the Mediterranean theater of operations.", "content": "Delayed internal fixation of compound battle fractures in the Mediterranean theater of operations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009334"}
{"pmid": "21009335", "title": "The incidence of complications in the use of transfixion pins and wires for skeletal traction.", "content": "The incidence of complications in the use of transfixion pins and wires for skeletal traction.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009335"}
{"pmid": "21009336", "title": "Abdominal surgery in an evacuation hospital.", "content": "Abdominal surgery in an evacuation hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009336"}
{"pmid": "21009337", "title": "Chemotherapy in traumatic surgery of the abdomen.", "content": "Chemotherapy in traumatic surgery of the abdomen.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009337"}
{"pmid": "21009340", "title": "The role of chemotherapy in wounds and surgical infections; clinical and bacteriologic studies.", "content": "The role of chemotherapy in wounds and surgical infections; clinical and bacteriologic studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009340"}
{"pmid": "21009338", "title": "Lung abscess complicating penetrating wounds of the chest.", "content": "Lung abscess complicating penetrating wounds of the chest.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009338"}
{"pmid": "21009341", "title": "Pain in men wounded in battle.", "content": "Pain in men wounded in battle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009341"}
{"pmid": "21009339", "title": "The operative treatment of decubitus ulcer.", "content": "The operative treatment of decubitus ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009339"}
{"pmid": "21009320", "title": "Sanitary laws in relation to public health.", "content": "Sanitary laws in relation to public health.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009320"}
{"pmid": "21009342", "title": "Retroperitoneal (mesenteric pouch) hernia.", "content": "Retroperitoneal (mesenteric pouch) hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009342"}
{"pmid": "21009343", "title": "Cystic disease of the liver.", "content": "Cystic disease of the liver.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009343"}
{"pmid": "21009344", "title": "Congenital cystic dilatation of the common bile duct.", "content": "Congenital cystic dilatation of the common bile duct.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009344"}
{"pmid": "21009345", "title": "Traumatic rupture of the gall-bladder.", "content": "Traumatic rupture of the gall-bladder.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009345"}
{"pmid": "21009346", "title": "Sarcoma complicating Paget's disease of bone.", "content": "Sarcoma complicating Paget's disease of bone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009346"}
{"pmid": "21009348", "title": "Pharyngeal diverticula.", "content": "Pharyngeal diverticula.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009348"}
{"pmid": "21009350", "title": "The surgical treatment of traumatic aneurysms.", "content": "The surgical treatment of traumatic aneurysms.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009350"}
{"pmid": "21009347", "title": "Extradural spinal hemorrhage.", "content": "Extradural spinal hemorrhage.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009347"}
{"pmid": "21009349", "title": "Acrylic resin for the closure of skull defects.", "content": "Acrylic resin for the closure of skull defects.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009349"}
{"pmid": "21009351", "title": "Some observations on carcinoma of the prostate treated with oestrogens, as demonstrated by serial biopsies.", "content": "Some observations on carcinoma of the prostate treated with oestrogens, as demonstrated by serial biopsies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009351"}
{"pmid": "21009352", "title": "A histological study of a predegenerated nerve autograft.", "content": "A histological study of a predegenerated nerve autograft.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009352"}
{"pmid": "21009353", "title": "Obstructive diaphragmatic hernia resulting from old gunshot wound of the chest; a report of three cases.", "content": "Obstructive diaphragmatic hernia resulting from old gunshot wound of the chest; a report of three cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009353"}
{"pmid": "21009354", "title": "Pelvic ectopic kidney.", "content": "Pelvic ectopic kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009354"}
{"pmid": "21009355", "title": "Torsion of the great omentum; report of four cases.", "content": "Torsion of the great omentum; report of four cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009355"}
{"pmid": "21009356", "title": "Physiological gastrectomy.", "content": "Physiological gastrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009356"}
{"pmid": "21009357", "title": "Thoraco-abdominal wounds in war.", "content": "Thoraco-abdominal wounds in war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009357"}
{"pmid": "21009358", "title": "Principles in early reconstructive surgery of severe thermal burns of the hands.", "content": "Principles in early reconstructive surgery of severe thermal burns of the hands.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009358"}
{"pmid": "21009360", "title": "Experiences with transthoracic oesophagectomy and gastrectomy.", "content": "Experiences with transthoracic oesophagectomy and gastrectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009360"}
{"pmid": "21009359", "title": "An aid in the post-operative management of temporary ileal fistula after the Lahey right hemicolectomy.", "content": "An aid in the post-operative management of temporary ileal fistula after the Lahey right hemicolectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009359"}
{"pmid": "21009361", "title": "Penicillin treatment of acute haematogenous osteomyelitis.", "content": "Penicillin treatment of acute haematogenous osteomyelitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009361"}
{"pmid": "21009362", "title": "The status of hormonal bio-assay in malignant disease of the testicle.", "content": "The status of hormonal bio-assay in malignant disease of the testicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009362"}
{"pmid": "21009363", "title": "Chronic hypertrophic ileocaecal tuberculosis, and its relation to regional ileitis (Crohn's disease).", "content": "Chronic hypertrophic ileocaecal tuberculosis, and its relation to regional ileitis (Crohn's disease).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009363"}
{"pmid": "21009364", "title": "Intussusception of the sigmoid due to simple polypus with annular carcinoma of the descending colon.", "content": "Intussusception of the sigmoid due to simple polypus with annular carcinoma of the descending colon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009364"}
{"pmid": "21009365", "title": "Hernia traversing the lesser sac.", "content": "Hernia traversing the lesser sac.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009365"}
{"pmid": "21009366", "title": "Carcinoma of the small intestines.", "content": "Carcinoma of the small intestines.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009366"}
{"pmid": "21009367", "title": "Hernia of the ileum through a hole in the transverse mesocolon.", "content": "Hernia of the ileum through a hole in the transverse mesocolon.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009367"}
{"pmid": "21009368", "title": "An enormous epithelioma adenoides cysticum of the scalp.", "content": "An enormous epithelioma adenoides cysticum of the scalp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009368"}
{"pmid": "21009369", "title": "Sarcoma of the metatarsal bones.", "content": "Sarcoma of the metatarsal bones.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009369"}
{"pmid": "21009370", "title": "A case of common iliac aneurysm in a child.", "content": "A case of common iliac aneurysm in a child.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009370"}
{"pmid": "21009372", "title": "A fibrolipoma of the cheek.", "content": "A fibrolipoma of the cheek.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009372"}
{"pmid": "21009371", "title": "A large testicular tumour.", "content": "A large testicular tumour.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009371"}
{"pmid": "21009383", "title": "Diagnosis and management of uterine carcinoma and sarcoma.", "content": "Diagnosis and management of uterine carcinoma and sarcoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009383"}
{"pmid": "21009384", "title": "Nonmalignant tumors of the uterine corpus.", "content": "Nonmalignant tumors of the uterine corpus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009384"}
{"pmid": "21009386", "title": "Nonmalignant diseases of the cervix.", "content": "Nonmalignant diseases of the cervix.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009386"}
{"pmid": "21009385", "title": "Merits and a technic for complete hysterectomy.", "content": "Merits and a technic for complete hysterectomy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009385"}
{"pmid": "21009387", "title": "Indications and contraindications in the irradiation therapy of benign uterine conditions.", "content": "Indications and contraindications in the irradiation therapy of benign uterine conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009387"}
{"pmid": "21009388", "title": "Backache in women and uterine retrodisplacement.", "content": "Backache in women and uterine retrodisplacement.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009388"}
{"pmid": "21009389", "title": "The treatment of habitual abortion with estrogen and progesterone.", "content": "The treatment of habitual abortion with estrogen and progesterone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009389"}
{"pmid": "21009391", "title": "Operations for sterility.", "content": "Operations for sterility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009391"}
{"pmid": "21009390", "title": "Uterosalpingography.", "content": "Uterosalpingography.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009390"}
{"pmid": "21009394", "title": "Roentgenological visualization of the sacral hiatus during late pregnancy.", "content": "Roentgenological visualization of the sacral hiatus during late pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009394"}
{"pmid": "21009392", "title": "The control of pain and fear in the management of labor and delivery.", "content": "The control of pain and fear in the management of labor and delivery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009392"}
{"pmid": "21009393", "title": "Continuous spinal and continuous caudal analgesia in cesarean section.", "content": "Continuous spinal and continuous caudal analgesia in cesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009393"}
{"pmid": "21009395", "title": "The roentgenological visualization of the placenta.", "content": "The roentgenological visualization of the placenta.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009395"}
{"pmid": "21009396", "title": "Hemorrhage of pregnancy.", "content": "Hemorrhage of pregnancy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009396"}
{"pmid": "21009399", "title": "Forceps for delivery; their use and abuse.", "content": "Forceps for delivery; their use and abuse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009399"}
{"pmid": "21009397", "title": "Ruptured uterus in the last trimester of pregnancy; a report of 105 cases.", "content": "Ruptured uterus in the last trimester of pregnancy; a report of 105 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009397"}
{"pmid": "21009403", "title": "Immediate care of the newborn.", "content": "Immediate care of the newborn.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009403"}
{"pmid": "21009398", "title": "Uterine contractions during pregnancy and labor observed with the tocograph.", "content": "Uterine contractions during pregnancy and labor observed with the tocograph.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009398"}
{"pmid": "21009401", "title": "External version.", "content": "External version.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009401"}
{"pmid": "21009402", "title": "Blood, blood derivatives and blood substitutes in obstetric and gynecologic practice.", "content": "Blood, blood derivatives and blood substitutes in obstetric and gynecologic practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009402"}
{"pmid": "21009400", "title": "The Waters operation in modern obstetrics.", "content": "The Waters operation in modern obstetrics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009400"}
{"pmid": "21009415", "title": "Report of case of acute hemorrhagic adrenalitis.", "content": "Report of case of acute hemorrhagic adrenalitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009415"}
{"pmid": "21009416", "title": "The relief of renal colic and renal suppression; a preliminary report.", "content": "The relief of renal colic and renal suppression; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009416"}
{"pmid": "21009417", "title": "A pyelographic sign in the diagnosis of perinephric abscess.", "content": "A pyelographic sign in the diagnosis of perinephric abscess.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009417"}
{"pmid": "21009418", "title": "Renal adenomas in hypernephromatous kidneys; a study of their incidence, nature and relationship.", "content": "Renal adenomas in hypernephromatous kidneys; a study of their incidence, nature and relationship.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009418"}
{"pmid": "21009419", "title": "Liposarcoma of kidney; report of a case presenting an unusual syndrome.", "content": "Liposarcoma of kidney; report of a case presenting an unusual syndrome.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009419"}
{"pmid": "21009420", "title": "Mucinous adenocarcinoma of the pelvis of the kidney.", "content": "Mucinous adenocarcinoma of the pelvis of the kidney.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009420"}
{"pmid": "21009421", "title": "Ureteropelvic obstructions in children; incidence and etiology.", "content": "Ureteropelvic obstructions in children; incidence and etiology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009421"}
{"pmid": "21009404", "title": "Physical medicine in the Army; its effect on civil practice.", "content": "Physical medicine in the Army; its effect on civil practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009404"}
{"pmid": "21009405", "title": "Minor industrial injuries; early recognition, prevention, notification and treatment.", "content": "Minor industrial injuries; early recognition, prevention, notification and treatment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009405"}
{"pmid": "21009406", "title": "The management of rheumatoid arthritis.", "content": "The management of rheumatoid arthritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009406"}
{"pmid": "21009423", "title": "Unusual ureteral anomalies; case reports.", "content": "Unusual ureteral anomalies; case reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009423"}
{"pmid": "21009422", "title": "Circumcaval ureter; report of a case with a consideration of the preoperative diagnosis and successful plastic repair.", "content": "Circumcaval ureter; report of a case with a consideration of the preoperative diagnosis and successful plastic repair.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009422"}
{"pmid": "21009424", "title": "Congenital diverticulum of the female urethra.", "content": "Congenital diverticulum of the female urethra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009424"}
{"pmid": "21009407", "title": "Social aspect of physical and industrial medicine.", "content": "Social aspect of physical and industrial medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009407"}
{"pmid": "21009408", "title": "Hydrological treatment of liver and gall-bladder disorders.", "content": "Hydrological treatment of liver and gall-bladder disorders.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009408"}
{"pmid": "21009425", "title": "A study of the effect of stilbestrol therapy on the size of the benignly hypertrophied prostate gland.", "content": "A study of the effect of stilbestrol therapy on the size of the benignly hypertrophied prostate gland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009425"}
{"pmid": "21009426", "title": "The importance of routine cystoscopy in prostatism.", "content": "The importance of routine cystoscopy in prostatism.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009426"}
{"pmid": "21009427", "title": "Osteitis pubis.", "content": "Osteitis pubis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009427"}
{"pmid": "21009428", "title": "An instrument for transurethral anesthesia.", "content": "An instrument for transurethral anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009428"}
{"pmid": "21009429", "title": "Urogenital complications of dengue fever.", "content": "Urogenital complications of dengue fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009429"}
{"pmid": "21009432", "title": "Evaluating potentialities of human spermatozoa.", "content": "Evaluating potentialities of human spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009432"}
{"pmid": "21009430", "title": "War injuries of the urinary tract.", "content": "War injuries of the urinary tract.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009430"}
{"pmid": "21009431", "title": "Urogenital wounds in an evacuation hospital.", "content": "Urogenital wounds in an evacuation hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009431"}
{"pmid": "21009433", "title": "Penicillin in propylene glycol; a preliminary report.", "content": "Penicillin in propylene glycol; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009433"}
{"pmid": "21009434", "title": "WAR against prostitution must go on; a report on the current status of commercialized prostitution.", "content": "WAR against prostitution must go on; a report on the current status of commercialized prostitution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009434"}
{"pmid": "21009435", "title": "Our strength is in united action; a report on progress in social protection in the States and communities with suggestions for more effective cooperation among agencies concerned.", "content": "Our strength is in united action; a report on progress in social protection in the States and communities with suggestions for more effective cooperation among agencies concerned.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009435"}
{"pmid": "21009436", "title": "The venereal disease heritage of World War II; a Navy view of demobilization and postwar venereal disease and social hygiene problems.", "content": "The venereal disease heritage of World War II; a Navy view of demobilization and postwar venereal disease and social hygiene problems.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009436"}
{"pmid": "21009437", "title": "Current Army venereal disease rates.", "content": "Current Army venereal disease rates.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009437"}
{"pmid": "21009438", "title": "The Army venereal disease education program for demobilization.", "content": "The Army venereal disease education program for demobilization.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009438"}
{"pmid": "21009440", "title": "Education for case-finding.", "content": "Education for case-finding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009440"}
{"pmid": "21009439", "title": "The postwar syphilis control problem in the United States.", "content": "The postwar syphilis control problem in the United States.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009439"}
{"pmid": "21009441", "title": "The synergistic action of penicillin and mapharsen (oxophenarsine hydrochloride) in the treatment of experimental syphilis.", "content": "The synergistic action of penicillin and mapharsen (oxophenarsine hydrochloride) in the treatment of experimental syphilis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009441"}
{"pmid": "21009442", "title": "San Francisco industrial venereal disease educational and case-finding program.", "content": "San Francisco industrial venereal disease educational and case-finding program.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009442"}
{"pmid": "21009443", "title": "Regarding the unusual effect of penicillin therapy upon the uterus.", "content": "Regarding the unusual effect of penicillin therapy upon the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009443"}
{"pmid": "21009444", "title": "Lead poisoning of cattle.", "content": "Lead poisoning of cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009444"}
{"pmid": "21009445", "title": "Studies of vesicular stomatitis with special reference to a virus of swine origin.", "content": "Studies of vesicular stomatitis with special reference to a virus of swine origin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009445"}
{"pmid": "21009446", "title": "An outbreak of salmonellosis in horses and mules.", "content": "An outbreak of salmonellosis in horses and mules.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009446"}
{"pmid": "21009447", "title": "INSPECTION OF Human food.", "content": "INSPECTION OF Human food.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009447"}
{"pmid": "21009449", "title": "The incidence of intestinal protozoa in the dog.", "content": "The incidence of intestinal protozoa in the dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009449"}
{"pmid": "21009450", "title": "Rabies in cattle.", "content": "Rabies in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009450"}
{"pmid": "21009451", "title": "Abortion in sheep following the administration of phenothiazine.", "content": "Abortion in sheep following the administration of phenothiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009451"}
{"pmid": "21009448", "title": "Experimental edema and ascites in poults.", "content": "Experimental edema and ascites in poults.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009448"}
{"pmid": "21009452", "title": "Skin grafting in a cat.", "content": "Skin grafting in a cat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009452"}
{"pmid": "21009454", "title": "PULLORUM disease; historical sketch.", "content": "PULLORUM disease; historical sketch.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009454"}
{"pmid": "21009453", "title": "A precocious heifer; cesarean section.", "content": "A precocious heifer; cesarean section.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009453"}
{"pmid": "21009455", "title": "POULTRY medicine.", "content": "POULTRY medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009455"}
{"pmid": "21009456", "title": "Tick infestation as an aetiological factor in diseases of unknown origin among cattle.", "content": "Tick infestation as an aetiological factor in diseases of unknown origin among cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009456"}
{"pmid": "21009458", "title": "A note on the efficacy of commercial anti-anthrax bacterins.", "content": "A note on the efficacy of commercial anti-anthrax bacterins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009458"}
{"pmid": "21009457", "title": "Modern therapeutics; a review of the use of sulphonamides and of penicillin and other antibiotics from bacteria and moulds as therapeutic agents.", "content": "Modern therapeutics; a review of the use of sulphonamides and of penicillin and other antibiotics from bacteria and moulds as therapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009457"}
{"pmid": "21009459", "title": "The excretion of tortoise shells by cattle.", "content": "The excretion of tortoise shells by cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009459"}
{"pmid": "21009460", "title": "The lung worm, Filaroides osleri (Cobbold) in South African bred dogs; preliminary note.", "content": "The lung worm, Filaroides osleri (Cobbold) in South African bred dogs; preliminary note.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009460"}
{"pmid": "21009461", "title": "The lung worm, Filaroides osleri (Cobbold) in dogs; a clinical report.", "content": "The lung worm, Filaroides osleri (Cobbold) in dogs; a clinical report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009461"}
{"pmid": "21009462", "title": "Milk fever in a ewe.", "content": "Milk fever in a ewe.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009462"}
{"pmid": "21009463", "title": "The relation of immunity in rabies to the antibody content of the serum.", "content": "The relation of immunity in rabies to the antibody content of the serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009463"}
{"pmid": "21009465", "title": "The adrenal bodies.", "content": "The adrenal bodies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009465"}
{"pmid": "21009464", "title": "Lymphatic leukemia with a myeloid blood picture complicated by a severe microcytic hypochromic anemia in a dog.", "content": "Lymphatic leukemia with a myeloid blood picture complicated by a severe microcytic hypochromic anemia in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009464"}
{"pmid": "21009466", "title": "The veterinarian and the poultry industry.", "content": "The veterinarian and the poultry industry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009466"}
{"pmid": "21009467", "title": "Fowl coccidiosis.", "content": "Fowl coccidiosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009467"}
{"pmid": "21009468", "title": "Trichinosis.", "content": "Trichinosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009468"}
{"pmid": "21009470", "title": "Complete foreign body obstruction of the duodenum.", "content": "Complete foreign body obstruction of the duodenum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009470"}
{"pmid": "21009469", "title": "Neurogenic sarcoma in a dog.", "content": "Neurogenic sarcoma in a dog.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009469"}
{"pmid": "21009471", "title": "Infectious equine encephalomyelitis in the United States in 1944.", "content": "Infectious equine encephalomyelitis in the United States in 1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009471"}
{"pmid": "21009473", "title": "Bovine mastitis caused by a Corynebacterium not previously described.", "content": "Bovine mastitis caused by a Corynebacterium not previously described.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009473"}
{"pmid": "21009474", "title": "Bovine obstetrical work.", "content": "Bovine obstetrical work.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009474"}
{"pmid": "21009476", "title": "Penicillin in veterinary medicine.", "content": "Penicillin in veterinary medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009476"}
{"pmid": "21009475", "title": "Some newer chemotherapeutic agents.", "content": "Some newer chemotherapeutic agents.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009475"}
{"pmid": "21009477", "title": "Unusual causes of death among dogs.", "content": "Unusual causes of death among dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009477"}
{"pmid": "21009479", "title": "Infectious pododermatitis in dairy cattle.", "content": "Infectious pododermatitis in dairy cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009479"}
{"pmid": "21009478", "title": "Trials with sodium fluoride as an ascaricide for swine.", "content": "Trials with sodium fluoride as an ascaricide for swine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009478"}
{"pmid": "21009480", "title": "Impacted sinuses in a cow.", "content": "Impacted sinuses in a cow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009480"}
{"pmid": "21009481", "title": "Tick paralysis in beef cattle due to Dermacentor andersoni.", "content": "Tick paralysis in beef cattle due to Dermacentor andersoni.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009481"}
{"pmid": "21009482", "title": "The brown dog tick, with special reference to its control and eradication.", "content": "The brown dog tick, with special reference to its control and eradication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009482"}
{"pmid": "21009472", "title": "About practice; an effective treatment for foot rot.", "content": "About practice; an effective treatment for foot rot.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009472"}
{"pmid": "21009483", "title": "Difficult fracture reduction with the aid of the Stader splint.", "content": "Difficult fracture reduction with the aid of the Stader splint.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009483"}
{"pmid": "21009484", "title": "Report of Special Committee on Canine Filariasis, Illinois State Veterinary Medical Association.", "content": "Report of Special Committee on Canine Filariasis, Illinois State Veterinary Medical Association.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009484"}
{"pmid": "21009485", "title": "Convulsions in dogs.", "content": "Convulsions in dogs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009485"}
{"pmid": "21009492", "title": "An infectious enteritis of young turkeys associated with Cochlosoma sp.", "content": "An infectious enteritis of young turkeys associated with Cochlosoma sp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009492"}
{"pmid": "21009493", "title": "Active immunisation as against passive segregation with reference to tuberculosis.", "content": "Active immunisation as against passive segregation with reference to tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009493"}
{"pmid": "21009495", "title": "Construction and architecture of a small animal clinic.", "content": "Construction and architecture of a small animal clinic.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009495"}
{"pmid": "21009494", "title": "Reflections on the planning of small animal hospitals.", "content": "Reflections on the planning of small animal hospitals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009494"}
{"pmid": "21009496", "title": "Essentials of a hospital for small animals.", "content": "Essentials of a hospital for small animals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009496"}
{"pmid": "21009497", "title": "The modern animal hospital.", "content": "The modern animal hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009497"}
{"pmid": "21009500", "title": "Veterinary education; the essentials of a modern vocational training and the proper rule of the universities in advancing specialised veterinary knowledge; a suggested programme.", "content": "Veterinary education; the essentials of a modern vocational training and the proper rule of the universities in advancing specialised veterinary knowledge; a suggested programme.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009500"}
{"pmid": "21009498", "title": "The veterinarian of World War II.", "content": "The veterinarian of World War II.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009498"}
{"pmid": "21009499", "title": "Reflections on the value of tartar emetic for the treatment of trypanosomiases.", "content": "Reflections on the value of tartar emetic for the treatment of trypanosomiases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009499"}
{"pmid": "21009501", "title": "Oestrogenic induction of lactation in cattle.", "content": "Oestrogenic induction of lactation in cattle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009501"}
{"pmid": "21009502", "title": "HUNDRED years, 1844-1944.", "content": "HUNDRED years, 1844-1944.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009502"}
{"pmid": "21009503", "title": "SHORT history of the veterinary art in antiquity.", "content": "SHORT history of the veterinary art in antiquity.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009503"}
{"pmid": "21009504", "title": "SHORT account of the circumstances which led to the petition for and the grant in 1844 of the charter of incorporation of the Royal College of Veterinary Surgeons.", "content": "SHORT account of the circumstances which led to the petition for and the grant in 1844 of the charter of incorporation of the Royal College of Veterinary Surgeons.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009504"}
{"pmid": "21009505", "title": "BRITISH veterinary colleges; the Royal Veterinary College and Hospital, London.", "content": "BRITISH veterinary colleges; the Royal Veterinary College and Hospital, London.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009505"}
{"pmid": "21009506", "title": "ROYAL (DICK) Veterinary College, Edinburgh.", "content": "ROYAL (DICK) Veterinary College, Edinburgh.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009506"}
{"pmid": "21009507", "title": "GLASGOW Veterinary College.", "content": "GLASGOW Veterinary College.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009507"}
{"pmid": "21009508", "title": "PUBLIC veterinary services in Great Britain and Ireland.", "content": "PUBLIC veterinary services in Great Britain and Ireland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009508"}
{"pmid": "21009509", "title": "MEAT inspection in England and Wales and in Scotland.", "content": "MEAT inspection in England and Wales and in Scotland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009509"}
{"pmid": "21009510", "title": "MILK in (a) England and Wales and (b) in Scotland.", "content": "MILK in (a) England and Wales and (b) in Scotland.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009510"}
{"pmid": "21009511", "title": "VETERINARY development in Canada.", "content": "VETERINARY development in Canada.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009511"}
{"pmid": "21009516", "title": "BRITISH veterinary periodicals.", "content": "BRITISH veterinary periodicals.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009516"}
{"pmid": "21009512", "title": "VETERINARY profession in South Africa.", "content": "VETERINARY profession in South Africa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009512"}
{"pmid": "21009513", "title": "DEVELOPMENT and achievements of the British India Civil Veterinary Services.", "content": "DEVELOPMENT and achievements of the British India Civil Veterinary Services.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009513"}
{"pmid": "21009514", "title": "GENERAL, or private, veterinary practice.", "content": "GENERAL, or private, veterinary practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009514"}
{"pmid": "21009515", "title": "SOME special aspects of veterinary practice.", "content": "SOME special aspects of veterinary practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009515"}
{"pmid": "21009517", "title": "Studies on virus diseases of fish; lymphocystis disease in Centrarchidae.", "content": "Studies on virus diseases of fish; lymphocystis disease in Centrarchidae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009517"}
{"pmid": "21009518", "title": "The innervation of the flexor digitorum profundus and lumbrical muscles.", "content": "The innervation of the flexor digitorum profundus and lumbrical muscles.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009518"}
{"pmid": "21009519", "title": "Hyperplastic changes in the nervous system of a frog (Rana) as associated with multiple functional limbs.", "content": "Hyperplastic changes in the nervous system of a frog (Rana) as associated with multiple functional limbs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009519"}
{"pmid": "21009520", "title": "A criterion of luteal activity in the mouse.", "content": "A criterion of luteal activity in the mouse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009520"}
{"pmid": "21009521", "title": "The extrusive growth and attrition of the incisors in Cynomys L. ludovicianus (Ord.).", "content": "The extrusive growth and attrition of the incisors in Cynomys L. ludovicianus (Ord.).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009521"}
{"pmid": "21009522", "title": "The distribution of alkaline phosphatase in the cyclic growth of the rat hair follicle.", "content": "The distribution of alkaline phosphatase in the cyclic growth of the rat hair follicle.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009522"}
{"pmid": "21009524", "title": "The postnatal development of the oviduct of the rat.", "content": "The postnatal development of the oviduct of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009524"}
{"pmid": "21009523", "title": "The effect of colchicine on early cleavage of mouse ova.", "content": "The effect of colchicine on early cleavage of mouse ova.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009523"}
{"pmid": "21009525", "title": "The localization of phosphatases in the Golgi region of intestinal and other epithelial cells.", "content": "The localization of phosphatases in the Golgi region of intestinal and other epithelial cells.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009525"}
{"pmid": "21009526", "title": "The study of nephridia and genital ducts since 1895.", "content": "The study of nephridia and genital ducts since 1895.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009526"}
{"pmid": "21009535", "title": "On the cerebral motor cortex of the ant-eater (Tamandua tetradactyla L.) preliminary report.", "content": "On the cerebral motor cortex of the ant-eater (Tamandua tetradactyla L.) preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009535"}
{"pmid": "21009529", "title": "Kroeber's Configurations of culture growth.", "content": "Kroeber's Configurations of culture growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009529"}
{"pmid": "21009527", "title": "Further notes on tobacco in New Guinea.", "content": "Further notes on tobacco in New Guinea.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009527"}
{"pmid": "21009528", "title": "Notes on Cheyenne child life.", "content": "Notes on Cheyenne child life.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009528"}
{"pmid": "21009549", "title": "The isolation of estrone sulfate from the urine of stallions.", "content": "The isolation of estrone sulfate from the urine of stallions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009549"}
{"pmid": "21009551", "title": "Studies in species adaptation; continuous exposure of paramecia to methylcholanthrene and other agents for more than five years.", "content": "Studies in species adaptation; continuous exposure of paramecia to methylcholanthrene and other agents for more than five years.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009551"}
{"pmid": "21009553", "title": "Methylcholanthrene and the environment of Paramecium.", "content": "Methylcholanthrene and the environment of Paramecium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009553"}
{"pmid": "21009552", "title": "Studies in species adaptation; continuous and discontinuous exposure of a flat-worm to methylcholanthrene and to phenanthrene.", "content": "Studies in species adaptation; continuous and discontinuous exposure of a flat-worm to methylcholanthrene and to phenanthrene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009552"}
{"pmid": "21009554", "title": "Organ changes in rats exposed repeatedly to lowered oxygen tension with reduced barometric pressure.", "content": "Organ changes in rats exposed repeatedly to lowered oxygen tension with reduced barometric pressure.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009554"}
{"pmid": "21009555", "title": "Effect of adrenalectomy and ovariectomy on mammary carcinogenesis in strain C3H mice.", "content": "Effect of adrenalectomy and ovariectomy on mammary carcinogenesis in strain C3H mice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009555"}
{"pmid": "21009556", "title": "Quantitative relation between the number of organized centers and tissue volume in regenerating masses of minced body sections of Hydra.", "content": "Quantitative relation between the number of organized centers and tissue volume in regenerating masses of minced body sections of Hydra.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009556"}
{"pmid": "21009561", "title": "The use of infra-red spectra for analysis.", "content": "The use of infra-red spectra for analysis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009561"}
{"pmid": "21009562", "title": "A dynamic method for observing the antimony chloride reaction with vitamin A and related substances.", "content": "A dynamic method for observing the antimony chloride reaction with vitamin A and related substances.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009562"}
{"pmid": "21009564", "title": "A colorimetric method for the determination of uranium in leach liquors.", "content": "A colorimetric method for the determination of uranium in leach liquors.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009564"}
{"pmid": "21009563", "title": "The estimation of sucrose in sugar-dried egg by polarimetric methods.", "content": "The estimation of sucrose in sugar-dried egg by polarimetric methods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009563"}
{"pmid": "21009565", "title": "Rapid colorimetric estimation of iodine in kelp.", "content": "Rapid colorimetric estimation of iodine in kelp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009565"}
{"pmid": "21009567", "title": "Sulfanilamide and respiration of Neurospora.", "content": "Sulfanilamide and respiration of Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009567"}
{"pmid": "21009568", "title": "The photochemical production of oxygen and hydrogen ion by isolated chloroplasts.", "content": "The photochemical production of oxygen and hydrogen ion by isolated chloroplasts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009568"}
{"pmid": "21009566", "title": "The effects of p-aminobenzoic acid, pantothenic acid and pyridoxin upon respiration of Neurospora.", "content": "The effects of p-aminobenzoic acid, pantothenic acid and pyridoxin upon respiration of Neurospora.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009566"}
{"pmid": "21009569", "title": "The urinary excretion of trigonelline- and nicotinic acid-like substances in human subjects after the ingestion of trigonelline and after smoking.", "content": "The urinary excretion of trigonelline- and nicotinic acid-like substances in human subjects after the ingestion of trigonelline and after smoking.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009569"}
{"pmid": "21009570", "title": "Studies on the biochemistry of Tetrahymena; folic acid as a growth factor for T. geleii W.", "content": "Studies on the biochemistry of Tetrahymena; folic acid as a growth factor for T. geleii W.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009570"}
{"pmid": "21009572", "title": "The fermentation of lactose by an extract of streptococcus thermophilus.", "content": "The fermentation of lactose by an extract of streptococcus thermophilus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009572"}
{"pmid": "21009571", "title": "Reagents for the detection of hydrogen peroxide production by bacteria in plate cultures (with notes for the preparation of 2,7-diaminofluorene dihydrochloride).", "content": "Reagents for the detection of hydrogen peroxide production by bacteria in plate cultures (with notes for the preparation of 2,7-diaminofluorene dihydrochloride).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009571"}
{"pmid": "21009575", "title": "Dispensability of dietary niacin for reproduction and lactation in the rat.", "content": "Dispensability of dietary niacin for reproduction and lactation in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009575"}
{"pmid": "21009574", "title": "Thermal destruction of influenza A virus hemagglutinin; the effect of pH.", "content": "Thermal destruction of influenza A virus hemagglutinin; the effect of pH.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009574"}
{"pmid": "21009573", "title": "Succinic dehydrogenase activity of certain endocrine tissues of the rat.", "content": "Succinic dehydrogenase activity of certain endocrine tissues of the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009573"}
{"pmid": "21009576", "title": "Note on the orcinol reagent.", "content": "Note on the orcinol reagent.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009576"}
{"pmid": "21009577", "title": "The Kiliani reaction as a direct measure of reducing groups.", "content": "The Kiliani reaction as a direct measure of reducing groups.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009577"}
{"pmid": "21009578", "title": "The production of riboflavin by Ashbya gossypii.", "content": "The production of riboflavin by Ashbya gossypii.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009578"}
{"pmid": "21009582", "title": "Electrophoretic analysis of swine plasma and serum.", "content": "Electrophoretic analysis of swine plasma and serum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009582"}
{"pmid": "21009579", "title": "Further studies on the metabolism of nicotinic acid and related compounds in the horse.", "content": "Further studies on the metabolism of nicotinic acid and related compounds in the horse.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009579"}
{"pmid": "21009580", "title": "Note on the poison produced by the Polydesmus (Fontaria) vicinus, Lin.", "content": "Note on the poison produced by the Polydesmus (Fontaria) vicinus, Lin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009580"}
{"pmid": "21009581", "title": "The application of the law of mass action to binding by proteins; interactions with calcium.", "content": "The application of the law of mass action to binding by proteins; interactions with calcium.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009581"}
{"pmid": "21009583", "title": "Failure to demonstrate transmethylation of homocystine by a strain of E. coli requiring methionine for growth.", "content": "Failure to demonstrate transmethylation of homocystine by a strain of E. coli requiring methionine for growth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009583"}
{"pmid": "21009587", "title": "Properties of catalysis of coupled oxidation of alcohols.", "content": "Properties of catalysis of coupled oxidation of alcohols.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009587"}
{"pmid": "21009584", "title": "The antibacterial activity of simple derivatives of 2-aminophenol.", "content": "The antibacterial activity of simple derivatives of 2-aminophenol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009584"}
{"pmid": "21009590", "title": "The production of penicillin using fractions obtained from aqueous extracts of pea (Pisum sativum).", "content": "The production of penicillin using fractions obtained from aqueous extracts of pea (Pisum sativum).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009590"}
{"pmid": "21009596", "title": "Anaemia of nutritional origin in the rat.", "content": "Anaemia of nutritional origin in the rat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009596"}
{"pmid": "21009594", "title": "Biochemical characterization of actions of chemotherapeutic agents: lack of gross displacement of pantothenate and p-aminobenzoate from micro-organisms, by pantoyltaurine and sulphanilamide.", "content": "Biochemical characterization of actions of chemotherapeutic agents: lack of gross displacement of pantothenate and p-aminobenzoate from micro-organisms, by pantoyltaurine and sulphanilamide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009594"}
{"pmid": "21009604", "title": "A comparison of five methods for determining starch content of wheat.", "content": "A comparison of five methods for determining starch content of wheat.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009604"}
{"pmid": "21009595", "title": "Isolation from liver of new factors essential for the growth of Lactobacillus helveticus and Streptococcus lactis R.", "content": "Isolation from liver of new factors essential for the growth of Lactobacillus helveticus and Streptococcus lactis R.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009595"}
{"pmid": "21009603", "title": "Polarimetric determination of starch in cereal products; critical studies of methods for the determination of starch in whole wheat, granular, and patent flours.", "content": "Polarimetric determination of starch in cereal products; critical studies of methods for the determination of starch in whole wheat, granular, and patent flours.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009603"}
{"pmid": "21009605", "title": "Equilibrium diagrams for binary mixtures of aniline, ethylaniline, and diethylaniline.", "content": "Equilibrium diagrams for binary mixtures of aniline, ethylaniline, and diethylaniline.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009605"}
{"pmid": "21009607", "title": "Dissimilation of glucose by Bacillus subtilis (Ford's strain).", "content": "Dissimilation of glucose by Bacillus subtilis (Ford's strain).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009607"}
{"pmid": "21009606", "title": "Determination of fluorides in water by means of a photoelectric colorimeter.", "content": "Determination of fluorides in water by means of a photoelectric colorimeter.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009606"}
{"pmid": "21009608", "title": "Catalytic dehydrogenation of primary and secondary alcohols with copper-chromium oxide.", "content": "Catalytic dehydrogenation of primary and secondary alcohols with copper-chromium oxide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009608"}
{"pmid": "21009609", "title": "The ether-soluble extractive of black sprucewood.", "content": "The ether-soluble extractive of black sprucewood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009609"}
{"pmid": "21009610", "title": "A note on the hydrogenation of beta-phenyl-alpha oximinopropionic acid.", "content": "A note on the hydrogenation of beta-phenyl-alpha oximinopropionic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009610"}
{"pmid": "21009611", "title": "Oxidation of 3,4-dimethoxycinnamic acid and substitution products with alkaline potassium permanganate solution.", "content": "Oxidation of 3,4-dimethoxycinnamic acid and substitution products with alkaline potassium permanganate solution.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009611"}
{"pmid": "21009612", "title": "The synthesis of 7-methoxy-l-isoquinolone.", "content": "The synthesis of 7-methoxy-l-isoquinolone.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009612"}
{"pmid": "21009613", "title": "Phenylation of some hydrocarbons with a phenyl halide activated by an alkali amide.", "content": "Phenylation of some hydrocarbons with a phenyl halide activated by an alkali amide.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009613"}
{"pmid": "21009614", "title": "6'-methoxyrubanol-9.", "content": "6'-methoxyrubanol-9.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009614"}
{"pmid": "21009615", "title": "Contributions to the study of marine products; spongosterol.", "content": "Contributions to the study of marine products; spongosterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009615"}
{"pmid": "21009616", "title": "Contributions to the study of marine products; microcionasterol and other sterols of sponges.", "content": "Contributions to the study of marine products; microcionasterol and other sterols of sponges.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009616"}
{"pmid": "21009617", "title": "Contributions to the study of marine products; chalinasterol.", "content": "Contributions to the study of marine products; chalinasterol.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009617"}
{"pmid": "21009618", "title": "Acyl interconversions of aryl polyacylglycosides.", "content": "Acyl interconversions of aryl polyacylglycosides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009618"}
{"pmid": "21009619", "title": "On stomatitis ulcerosa; etiology and therapeutics.", "content": "On stomatitis ulcerosa; etiology and therapeutics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009619"}
{"pmid": "21009620", "title": "Decrease in the incidence of dental caries in 6-7 years old Copenhagen elementary school children 1936-1943.", "content": "Decrease in the incidence of dental caries in 6-7 years old Copenhagen elementary school children 1936-1943.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009620"}
{"pmid": "21009621", "title": "The combination bread-sugar as a cause for dental caries.", "content": "The combination bread-sugar as a cause for dental caries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009621"}
{"pmid": "21009623", "title": "The Brantford fluorine experiment.", "content": "The Brantford fluorine experiment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009623"}
{"pmid": "21009622", "title": "Mandibular movements and the arrangement of teeth.", "content": "Mandibular movements and the arrangement of teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009622"}
{"pmid": "21009627", "title": "Study of congenitally missing second premolars and space factors in the arches.", "content": "Study of congenitally missing second premolars and space factors in the arches.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009627"}
{"pmid": "21009628", "title": "Electron microscope study of the mechanism of fluorine deposition in teeth.", "content": "Electron microscope study of the mechanism of fluorine deposition in teeth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009628"}
{"pmid": "21009629", "title": "The effect of sodium fluoride on the solubility of calcium phosphate, tooth enamel and whole teeth in lactic acid.", "content": "The effect of sodium fluoride on the solubility of calcium phosphate, tooth enamel and whole teeth in lactic acid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009629"}
{"pmid": "21009630", "title": "Observations on induced caries in rats; effects of excessive sugar in the diet.", "content": "Observations on induced caries in rats; effects of excessive sugar in the diet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009630"}
{"pmid": "21009631", "title": "Studies on the oxidation-reduction potentials of saliva.", "content": "Studies on the oxidation-reduction potentials of saliva.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009631"}
{"pmid": "21009632", "title": "Evaluation of antimicrobial agents; the germicidal activity of a synthetic detergent, DC-12.", "content": "Evaluation of antimicrobial agents; the germicidal activity of a synthetic detergent, DC-12.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009632"}
{"pmid": "21009633", "title": "Status of fluoride therapy in dentistry.", "content": "Status of fluoride therapy in dentistry.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009633"}
{"pmid": "21009634", "title": "Systemic introduction of sodium iodide into calcified dental tissues.", "content": "Systemic introduction of sodium iodide into calcified dental tissues.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009634"}
{"pmid": "21009636", "title": "Evolution of orthodontic theory and practice.", "content": "Evolution of orthodontic theory and practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009636"}
{"pmid": "21009637", "title": "Graduate training in oral surgery.", "content": "Graduate training in oral surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009637"}
{"pmid": "21009639", "title": "Study of one hundred fifty cases of fracture of the upper jaw in an overseas maxillofacial center.", "content": "Study of one hundred fifty cases of fracture of the upper jaw in an overseas maxillofacial center.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009639"}
{"pmid": "21009635", "title": "The histological demonstration of phosphatase in the development of the enamel organ.", "content": "The histological demonstration of phosphatase in the development of the enamel organ.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009635"}
{"pmid": "21009638", "title": "Control of bone fragments in maxillofacial surgery.", "content": "Control of bone fragments in maxillofacial surgery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009638"}
{"pmid": "21009640", "title": "Correction of abnormal mandibular protrusion by intra-oral operation.", "content": "Correction of abnormal mandibular protrusion by intra-oral operation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009640"}
{"pmid": "21009641", "title": "Avoidance of severe anoxia in nitrous oxide anesthesia.", "content": "Avoidance of severe anoxia in nitrous oxide anesthesia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009641"}
{"pmid": "21009642", "title": "Unerupted supernumerary mandibular bicuspids; report of case.", "content": "Unerupted supernumerary mandibular bicuspids; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009642"}
{"pmid": "21009643", "title": "Observations on the definitive treatment of maxillofacial injuries.", "content": "Observations on the definitive treatment of maxillofacial injuries.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009643"}
{"pmid": "21009645", "title": "Acetylsalicylic acid (aspirin) as a cause of bleeding.", "content": "Acetylsalicylic acid (aspirin) as a cause of bleeding.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009645"}
{"pmid": "21009648", "title": "Making dentistry a reading profession.", "content": "Making dentistry a reading profession.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009648"}
{"pmid": "21009646", "title": "Papillary cystadenoma lymphomatosum (adenolymphoma) of the parotid region; report of case.", "content": "Papillary cystadenoma lymphomatosum (adenolymphoma) of the parotid region; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009646"}
{"pmid": "21009644", "title": "Treatment of gunshot fractures of the mandible.", "content": "Treatment of gunshot fractures of the mandible.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009644"}
{"pmid": "21009647", "title": "Penicillin in submandibular cellulitis and clinical septicemia; report of case.", "content": "Penicillin in submandibular cellulitis and clinical septicemia; report of case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009647"}
{"pmid": "21009649", "title": "Discoloration of acrylic resins for tooth restorations.", "content": "Discoloration of acrylic resins for tooth restorations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009649"}
{"pmid": "21009651", "title": "Prothesenhygiene.", "content": "Prothesenhygiene.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009651"}
{"pmid": "21009650", "title": "A clinical investigation of some hemostatic agents applied to different lesions of the mouth.", "content": "A clinical investigation of some hemostatic agents applied to different lesions of the mouth.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009650"}
{"pmid": "21009659", "title": "Acne vulgaris occurring in the tropics in a pigmentary and pilosebaceous nevus.", "content": "Acne vulgaris occurring in the tropics in a pigmentary and pilosebaceous nevus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009659"}
{"pmid": "21009657", "title": "Carbohydrate metabolism and the skin.", "content": "Carbohydrate metabolism and the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009657"}
{"pmid": "21009658", "title": "Epidermolysis bullosa; a suggestion as to possible causation.", "content": "Epidermolysis bullosa; a suggestion as to possible causation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009658"}
{"pmid": "21009662", "title": "Dermatology in an Army station hospital serving in Italy.", "content": "Dermatology in an Army station hospital serving in Italy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009662"}
{"pmid": "21009660", "title": "Effect of endocrine substances on the adult human scalp.", "content": "Effect of endocrine substances on the adult human scalp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009660"}
{"pmid": "21009661", "title": "Epidermodysplasia hystricoidis bullosa; report of a case with histopathologic study.", "content": "Epidermodysplasia hystricoidis bullosa; report of a case with histopathologic study.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009661"}
{"pmid": "21009663", "title": "Fixed bullous eruption due to sulfathiazole.", "content": "Fixed bullous eruption due to sulfathiazole.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009663"}
{"pmid": "21009664", "title": "Treatment of dermatoses with vasodilators.", "content": "Treatment of dermatoses with vasodilators.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009664"}
{"pmid": "21009665", "title": "Pigmentation of hair on transplanted skin in hooded rats.", "content": "Pigmentation of hair on transplanted skin in hooded rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009665"}
{"pmid": "21009666", "title": "Lichen sclerosus et atrophicus in childhood.", "content": "Lichen sclerosus et atrophicus in childhood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009666"}
{"pmid": "21009668", "title": "Sandals, and hygiene and infections of the feet.", "content": "Sandals, and hygiene and infections of the feet.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009668"}
{"pmid": "21009667", "title": "Differentiation of lepromatous from neural leprosy; the basis, a method, and report of five cases.", "content": "Differentiation of lepromatous from neural leprosy; the basis, a method, and report of five cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009667"}
{"pmid": "21009669", "title": "The adrenal glands in pemphigus vulgaris; report of six autopsies and review of the literature.", "content": "The adrenal glands in pemphigus vulgaris; report of six autopsies and review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009669"}
{"pmid": "21009674", "title": "Waterhouse-Friderichsen syndrome; report of a case.", "content": "Waterhouse-Friderichsen syndrome; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009674"}
{"pmid": "21009676", "title": "Carbarsone in the treatment of pemphigus; a preliminary report.", "content": "Carbarsone in the treatment of pemphigus; a preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009676"}
{"pmid": "21009681", "title": "A case for diagnosis (sarcoid; late cutaneous syphilid?).", "content": "A case for diagnosis (sarcoid; late cutaneous syphilid?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009681"}
{"pmid": "21009671", "title": "Dermatitis venenata following use of penicillin ointment.", "content": "Dermatitis venenata following use of penicillin ointment.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009671"}
{"pmid": "21009670", "title": "Cutaneous and subcutaneous lesions of the lower limbs in connection with the veins; differential diagnosis.", "content": "Cutaneous and subcutaneous lesions of the lower limbs in connection with the veins; differential diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009670"}
{"pmid": "21009673", "title": "Dermatitis medicamentosa associated with secondary polycythemia; report of a case.", "content": "Dermatitis medicamentosa associated with secondary polycythemia; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009673"}
{"pmid": "21009672", "title": "New cutaneous bactericidal agent used in soap; further practical studies.", "content": "New cutaneous bactericidal agent used in soap; further practical studies.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009672"}
{"pmid": "21009677", "title": "Fever and sterile abscess formation accompanying treatment of syphilis with penicillin.", "content": "Fever and sterile abscess formation accompanying treatment of syphilis with penicillin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009677"}
{"pmid": "21009695", "title": "Common ailments of quality in processed foods.", "content": "Common ailments of quality in processed foods.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009695"}
{"pmid": "21009679", "title": "Demonstration of effect of nutrition on the skin.", "content": "Demonstration of effect of nutrition on the skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009679"}
{"pmid": "21009678", "title": "Erysipeloid treated successfully with injections of penicillin report of a case.", "content": "Erysipeloid treated successfully with injections of penicillin report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009678"}
{"pmid": "21009696", "title": "Lecithin increases the effect of shortening in bread.", "content": "Lecithin increases the effect of shortening in bread.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009696"}
{"pmid": "21009697", "title": "Control of microbiological food spoilage by fumigation with epoxides.", "content": "Control of microbiological food spoilage by fumigation with epoxides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009697"}
{"pmid": "21009698", "title": "What sanitation means to the processor.", "content": "What sanitation means to the processor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009698"}
{"pmid": "21009680", "title": "Bowen's disease of penis; late latent syphilis (treated).", "content": "Bowen's disease of penis; late latent syphilis (treated).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009680"}
{"pmid": "21009699", "title": "How meat is dehydrated in New Zealand.", "content": "How meat is dehydrated in New Zealand.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009699"}
{"pmid": "21009700", "title": "Oil of angelica; production and characteristics.", "content": "Oil of angelica; production and characteristics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009700"}
{"pmid": "21009688", "title": "Systematized epithelial nevus.", "content": "Systematized epithelial nevus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009688"}
{"pmid": "21009684", "title": "A case for diagnosis (lupus vulgaris erythematosus of Leloir?).", "content": "A case for diagnosis (lupus vulgaris erythematosus of Leloir?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009684"}
{"pmid": "21009682", "title": "Postsyphilitic dyschromia; late dyschromic pinta? (treated).", "content": "Postsyphilitic dyschromia; late dyschromic pinta? (treated).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009682"}
{"pmid": "21009707", "title": "Cytological studies in Culex; somatic reduction divisions.", "content": "Cytological studies in Culex; somatic reduction divisions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009707"}
{"pmid": "21009683", "title": "Pyoderma gangrenosum associated with nonspecific ulcerative colitis.", "content": "Pyoderma gangrenosum associated with nonspecific ulcerative colitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009683"}
{"pmid": "21009705", "title": "On lethal mutations in natural populations.", "content": "On lethal mutations in natural populations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009705"}
{"pmid": "21009704", "title": "A study in gene action using different dosages and alleles of vestigial in Drosophila melanogaster.", "content": "A study in gene action using different dosages and alleles of vestigial in Drosophila melanogaster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009704"}
{"pmid": "21009706", "title": "Isolation by distance under diverse systems of mating.", "content": "Isolation by distance under diverse systems of mating.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009706"}
{"pmid": "21009686", "title": "Trichophytosis barbae.", "content": "Trichophytosis barbae.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009686"}
{"pmid": "21009708", "title": "Cytological studies in Culex; diploid and meiotic divisions.", "content": "Cytological studies in Culex; diploid and meiotic divisions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009708"}
{"pmid": "21009685", "title": "Dystrophia mediana canaliformis.", "content": "Dystrophia mediana canaliformis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009685"}
{"pmid": "21009687", "title": "Scleroderma en coup de sabre.", "content": "Scleroderma en coup de sabre.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009687"}
{"pmid": "21009693", "title": "Alopecia prematura.", "content": "Alopecia prematura.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009693"}
{"pmid": "21009689", "title": "Adenoma sebaceum (Pringle type forme fruste).", "content": "Adenoma sebaceum (Pringle type forme fruste).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009689"}
{"pmid": "21009690", "title": "Herpes simplex resembling herpes zoster.", "content": "Herpes simplex resembling herpes zoster.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009690"}
{"pmid": "21009692", "title": "A case for diagnosis (allergic eruption?).", "content": "A case for diagnosis (allergic eruption?).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009692"}
{"pmid": "21009694", "title": "Sarcoid.", "content": "Sarcoid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009694"}
{"pmid": "21009675", "title": "Colloidoclastic shock following injection of oxophenarsine hydrochloride (mapharsen).", "content": "Colloidoclastic shock following injection of oxophenarsine hydrochloride (mapharsen).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009675"}
{"pmid": "21009691", "title": "Recurrent urticaria chronica.", "content": "Recurrent urticaria chronica.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009691"}
{"pmid": "21009703", "title": "THE McNAGHTEN Rules and the irresistible impulse defence.", "content": "THE McNAGHTEN Rules and the irresistible impulse defence.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009703"}
{"pmid": "21009701", "title": "The need for reform in statutes affecting illegitimacy.", "content": "The need for reform in statutes affecting illegitimacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009701"}
{"pmid": "21009702", "title": "Medico-legal examinations and reports.", "content": "Medico-legal examinations and reports.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009702"}
{"pmid": "21009709", "title": "The selective elimination of inversion dicentric chromatids during meiosis in the eggs of Sciara impatiens.", "content": "The selective elimination of inversion dicentric chromatids during meiosis in the eggs of Sciara impatiens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009709"}
{"pmid": "21009710", "title": "Metabolism and motility of spermatozoa.", "content": "Metabolism and motility of spermatozoa.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009710"}
{"pmid": "21009711", "title": "Intramural hospital contraceptive clinics.", "content": "Intramural hospital contraceptive clinics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009711"}
{"pmid": "21009712", "title": "EUGENIC sterilization in North Carolina.", "content": "EUGENIC sterilization in North Carolina.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009712"}
{"pmid": "21009713", "title": "MOHAMMEDAN population.", "content": "MOHAMMEDAN population.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009713"}
{"pmid": "21009714", "title": "Commercially available mechanical devices for use in contraception.", "content": "Commercially available mechanical devices for use in contraception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009714"}
{"pmid": "21009715", "title": "Psychosomatic problems in fertility.", "content": "Psychosomatic problems in fertility.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009715"}
{"pmid": "21009716", "title": "FREUD on contraception.", "content": "FREUD on contraception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009716"}
{"pmid": "21009717", "title": "USE of estrogens in the control of conception.", "content": "USE of estrogens in the control of conception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009717"}
{"pmid": "21009718", "title": "BASAL temperature charts.", "content": "BASAL temperature charts.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009718"}
{"pmid": "21009722", "title": "Uterus didelphys.", "content": "Uterus didelphys.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009722"}
{"pmid": "21009723", "title": "Past memories.", "content": "Past memories.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009723"}
{"pmid": "21009724", "title": "Toxaemias of pregnancy in Kashmir.", "content": "Toxaemias of pregnancy in Kashmir.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009724"}
{"pmid": "21009725", "title": "Uterine haemorrhage without demonstrable pathology.", "content": "Uterine haemorrhage without demonstrable pathology.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009725"}
{"pmid": "21009726", "title": "Some congenital deformities; their treatment and prognosis.", "content": "Some congenital deformities; their treatment and prognosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009726"}
{"pmid": "21009727", "title": "Midwives and medical aid.", "content": "Midwives and medical aid.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009727"}
{"pmid": "21009735", "title": "Sulfa drugs and penicillin in pyogenic meningitis.", "content": "Sulfa drugs and penicillin in pyogenic meningitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009735"}
{"pmid": "21009736", "title": "Electrical measurements of the healing rate of human skin.", "content": "Electrical measurements of the healing rate of human skin.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009736"}
{"pmid": "21009737", "title": "Influence of ephedrine sulfate on blood pressure in hypertensive rats.", "content": "Influence of ephedrine sulfate on blood pressure in hypertensive rats.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009737"}
{"pmid": "21009738", "title": "Some thoughts on the status of gastric surgery in peptic ulcer.", "content": "Some thoughts on the status of gastric surgery in peptic ulcer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009738"}
{"pmid": "21009739", "title": "SOME interesting animal parasites.", "content": "SOME interesting animal parasites.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009739"}
{"pmid": "21009740", "title": "HEALTH insurance awaits taxing decisions.", "content": "HEALTH insurance awaits taxing decisions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009740"}
{"pmid": "21009741", "title": "The old becomes the new.", "content": "The old becomes the new.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009741"}
{"pmid": "21009742", "title": "Life begins in safety in this remodeled nursery.", "content": "Life begins in safety in this remodeled nursery.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009742"}
{"pmid": "21009743", "title": "Venereal disease control.", "content": "Venereal disease control.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009743"}
{"pmid": "21009744", "title": "Efficiency and economy should determine nursing needs.", "content": "Efficiency and economy should determine nursing needs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009744"}
{"pmid": "21009745", "title": "Redwoods form the background for the new Trinity Hospital.", "content": "Redwoods form the background for the new Trinity Hospital.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009745"}
{"pmid": "21009746", "title": "Should America have compulsory health insurance?", "content": "Should America have compulsory health insurance?", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009746"}
{"pmid": "21009747", "title": "Chronic disease from a patient's point of view.", "content": "Chronic disease from a patient's point of view.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009747"}
{"pmid": "21009748", "title": "How Buffalo fought polio.", "content": "How Buffalo fought polio.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009748"}
{"pmid": "21009749", "title": "The treatment of diabetics.", "content": "The treatment of diabetics.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009749"}
{"pmid": "21009750", "title": "Bed rest in tuberculosis.", "content": "Bed rest in tuberculosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009750"}
{"pmid": "21009752", "title": "How to use DDT.", "content": "How to use DDT.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009752"}
{"pmid": "21009751", "title": "The G.I. and hospital pharmacy.", "content": "The G.I. and hospital pharmacy.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009751"}
{"pmid": "21009767", "title": "Scrub typhus fever (Tsutsugamushi disease) in New Guinea; report of 75 cases.", "content": "Scrub typhus fever (Tsutsugamushi disease) in New Guinea; report of 75 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009767"}
{"pmid": "21009766", "title": "Prefrontal lobotomy; survey of 331 cases.", "content": "Prefrontal lobotomy; survey of 331 cases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009766"}
{"pmid": "21009768", "title": "The clinical significance of cold hemagglutinins.", "content": "The clinical significance of cold hemagglutinins.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009768"}
{"pmid": "21009769", "title": "Clinical arrest in enterococcal endocarditis.", "content": "Clinical arrest in enterococcal endocarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009769"}
{"pmid": "21009775", "title": "A simplified apparatus for the induction of artificial pneumoperitoneum.", "content": "A simplified apparatus for the induction of artificial pneumoperitoneum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009775"}
{"pmid": "21009770", "title": "The use of a modified globin from human erythrocytes in hypoproteinemias.", "content": "The use of a modified globin from human erythrocytes in hypoproteinemias.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009770"}
{"pmid": "21009771", "title": "Fatal agranulocytosis with autopsy following the use of thiouracil in a case of thyrotoxicosis.", "content": "Fatal agranulocytosis with autopsy following the use of thiouracil in a case of thyrotoxicosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009771"}
{"pmid": "21009772", "title": "The therapeutic value of early physical activity in rheumatic fever; preliminary report.", "content": "The therapeutic value of early physical activity in rheumatic fever; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009772"}
{"pmid": "21009774", "title": "Palmar erythema; its relationship to protein deficiency.", "content": "Palmar erythema; its relationship to protein deficiency.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009774"}
{"pmid": "21009773", "title": "The relationship of blood pressure and serum thiocyanate.", "content": "The relationship of blood pressure and serum thiocyanate.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009773"}
{"pmid": "21009776", "title": "The occurrence of fibrinolysis in shock, with observations on the prothrombin time and the plasma fibrinogen during hemorrhagic shock.", "content": "The occurrence of fibrinolysis in shock, with observations on the prothrombin time and the plasma fibrinogen during hemorrhagic shock.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009776"}
{"pmid": "21009777", "title": "Observations on the specificity and clinical use of Dirofilaria immitis antigen in the diagnosis of human filariasis (Wuchereria bancrofti).", "content": "Observations on the specificity and clinical use of Dirofilaria immitis antigen in the diagnosis of human filariasis (Wuchereria bancrofti).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009777"}
{"pmid": "21009778", "title": "The treatment of bacillary dysentery in Chinese soldiers with sulfaguanidine and sulfadiazine.", "content": "The treatment of bacillary dysentery in Chinese soldiers with sulfaguanidine and sulfadiazine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009778"}
{"pmid": "21009779", "title": "Infectious polyneuritis (Guillain-Barre syndrome).", "content": "Infectious polyneuritis (Guillain-Barre syndrome).", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009779"}
{"pmid": "21009781", "title": "Polyarteritis nodosa; report of 11 cases with review of recent literature.", "content": "Polyarteritis nodosa; report of 11 cases with review of recent literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009781"}
{"pmid": "21009780", "title": "Cranial arteritis; a critical evaluation of the syndrome of temporal arteritis with report of a case.", "content": "Cranial arteritis; a critical evaluation of the syndrome of temporal arteritis with report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009780"}
{"pmid": "21009785", "title": "Liver function studies in diabetes mellitus.", "content": "Liver function studies in diabetes mellitus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009785"}
{"pmid": "21009783", "title": "A study of one hundred cases with a positive coccidioidin skin test.", "content": "A study of one hundred cases with a positive coccidioidin skin test.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009783"}
{"pmid": "21009782", "title": "Some unusual thoracic complications of typhoid and Salmonella infections.", "content": "Some unusual thoracic complications of typhoid and Salmonella infections.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009782"}
{"pmid": "21009784", "title": "Short P-R interval, prolonged QRS complex (Wolff, Parkinson, White syndrome); report of fourteen cases and a review of the literature.", "content": "Short P-R interval, prolonged QRS complex (Wolff, Parkinson, White syndrome); report of fourteen cases and a review of the literature.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009784"}
{"pmid": "21009786", "title": "What can be accomplished in the treatment of heart diseases.", "content": "What can be accomplished in the treatment of heart diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009786"}
{"pmid": "21009788", "title": "Acute hemolytic anemia due to neoarsphenamine; report of a fatal case.", "content": "Acute hemolytic anemia due to neoarsphenamine; report of a fatal case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009788"}
{"pmid": "21009787", "title": "An apparatus for the introduction of penicillin aerosol into the nasal accessory sinuses with a case report of a patient with chronic sinusitis.", "content": "An apparatus for the introduction of penicillin aerosol into the nasal accessory sinuses with a case report of a patient with chronic sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009787"}
{"pmid": "21009789", "title": "The syndrome of compression of the pulmonary artery by a syphilitic aortic aneurysm with or without arterio-arterial communication.", "content": "The syndrome of compression of the pulmonary artery by a syphilitic aortic aneurysm with or without arterio-arterial communication.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009789"}
{"pmid": "21009790", "title": "Paroxymal ventricular tachycardia occurring in the absence of demonstrable heart disease.", "content": "Paroxymal ventricular tachycardia occurring in the absence of demonstrable heart disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009790"}
{"pmid": "21009791", "title": "Electrocardiographic changes following heat stroke; report of a case.", "content": "Electrocardiographic changes following heat stroke; report of a case.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009791"}
{"pmid": "21009792", "title": "PH factor.", "content": "PH factor.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009792"}
{"pmid": "21009793", "title": "Modern conceptions in the treatment of inguinal hernia.", "content": "Modern conceptions in the treatment of inguinal hernia.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009793"}
{"pmid": "21009797", "title": "Cancrum oris.", "content": "Cancrum oris.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009797"}
{"pmid": "21009795", "title": "A short note on the practical measures against plague.", "content": "A short note on the practical measures against plague.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009795"}
{"pmid": "21009794", "title": "Sulphathiazole (cibazol) in diarrhoeic conditions.", "content": "Sulphathiazole (cibazol) in diarrhoeic conditions.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009794"}
{"pmid": "21009796", "title": "Atebrine brand of amyl-acridine derivative in human malaria.", "content": "Atebrine brand of amyl-acridine derivative in human malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009796"}
{"pmid": "21009799", "title": "Vertigo and its importance in diagnosis.", "content": "Vertigo and its importance in diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009799"}
{"pmid": "21009798", "title": "Baby's cry and its significations.", "content": "Baby's cry and its significations.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009798"}
{"pmid": "21009800", "title": "Urine as an aid to diagnosis.", "content": "Urine as an aid to diagnosis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009800"}
{"pmid": "21009801", "title": "Glaucoma.", "content": "Glaucoma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009801"}
{"pmid": "21009802", "title": "Anaemia in tea gardens.", "content": "Anaemia in tea gardens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009802"}
{"pmid": "21009803", "title": "Cancrum oris and some other types of stomatitis.", "content": "Cancrum oris and some other types of stomatitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009803"}
{"pmid": "21009804", "title": "Diseases mentioned in the 17th and 18th century records of Fort St. George.", "content": "Diseases mentioned in the 17th and 18th century records of Fort St. George.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009804"}
{"pmid": "21009805", "title": "Penicillin for human foot and mouth disease.", "content": "Penicillin for human foot and mouth disease.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009805"}
{"pmid": "21009806", "title": "Teratodymes, monosomians.", "content": "Teratodymes, monosomians.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009806"}
{"pmid": "21009807", "title": "An interesting case of fowl-poisoning.", "content": "An interesting case of fowl-poisoning.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009807"}
{"pmid": "21009808", "title": "A case of round-worms complicated with malaria.", "content": "A case of round-worms complicated with malaria.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009808"}
{"pmid": "21009812", "title": "[The rate of regeneration of the peripheral nerves in mammalia; second communication].", "content": "[The rate of regeneration of the peripheral nerves in mammalia; second communication].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009812"}
{"pmid": "21009809", "title": "Malaria with strange history.", "content": "Malaria with strange history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009809"}
{"pmid": "21009810", "title": "[On the concomitant change of excitability in the nerve in parabiosis by pressure].", "content": "[On the concomitant change of excitability in the nerve in parabiosis by pressure].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009810"}
{"pmid": "21009811", "title": "[The action of the muscles on the nerves and on the cerebro-spinal centres; myogenetic analysis and functional observations].", "content": "[The action of the muscles on the nerves and on the cerebro-spinal centres; myogenetic analysis and functional observations].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009811"}
{"pmid": "21009813", "title": "[Polarizational effect on the nerve commissure of anodent under the action of acetylcholin].", "content": "[Polarizational effect on the nerve commissure of anodent under the action of acetylcholin].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009813"}
{"pmid": "21009814", "title": "[On the current of action of the frog's sartorius].", "content": "[On the current of action of the frog's sartorius].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009814"}
{"pmid": "21009816", "title": "[Chronaxia and rheobase of the eye in gunshot damages of the optical routes].", "content": "[Chronaxia and rheobase of the eye in gunshot damages of the optical routes].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009816"}
{"pmid": "21009815", "title": "[Refractoriness of muscle on direct and indirect irritation].", "content": "[Refractoriness of muscle on direct and indirect irritation].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009815"}
{"pmid": "21009818", "title": "[On shock as a neuro-distrophic process and on its treatment].", "content": "[On shock as a neuro-distrophic process and on its treatment].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009818"}
{"pmid": "21009819", "title": "[On the pathogenesis of traumatic shock].", "content": "[On the pathogenesis of traumatic shock].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009819"}
{"pmid": "21009817", "title": "[The effect of the stimulator-schizandra on neuro-muscular excitability in man].", "content": "[The effect of the stimulator-schizandra on neuro-muscular excitability in man].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009817"}
{"pmid": "21009822", "title": "[On the activation of the mesenchyma in acute inflammation].", "content": "[On the activation of the mesenchyma in acute inflammation].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009822"}
{"pmid": "21009821", "title": "[Biologically active substances in the exudation of tuberculous pleurisy].", "content": "[Biologically active substances in the exudation of tuberculous pleurisy].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009821"}
{"pmid": "21009824", "title": "[The secretory activity of the pancreas under reduced barometric pressure].", "content": "[The secretory activity of the pancreas under reduced barometric pressure].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009824"}
{"pmid": "21009823", "title": "[The state of the secretory and motor functions of the digestive tract on immediate action of kalium and calcium on the nerve centres].", "content": "[The state of the secretory and motor functions of the digestive tract on immediate action of kalium and calcium on the nerve centres].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009823"}
{"pmid": "21009826", "title": "[The changes of the oxidation ratio of the blood and urine in various stages of Brown-Pearce's cancer development].", "content": "[The changes of the oxidation ratio of the blood and urine in various stages of Brown-Pearce's cancer development].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009826"}
{"pmid": "21009830", "title": "[Experiment in the morphological analysis of the rami of the nervi intercostales of the diaphragm].", "content": "[Experiment in the morphological analysis of the rami of the nervi intercostales of the diaphragm].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009830"}
{"pmid": "21009832", "title": "[On the nature of the chemical receptors of the sinus carotici; the action of natrium acid on the sinus carotici].", "content": "[On the nature of the chemical receptors of the sinus carotici; the action of natrium acid on the sinus carotici].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009832"}
{"pmid": "21009827", "title": "[On the role of the liver in autoregulation of the blood sugar level; the liver function in depancreatized and epinephrectomized animals].", "content": "[On the role of the liver in autoregulation of the blood sugar level; the liver function in depancreatized and epinephrectomized animals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009827"}
{"pmid": "21009825", "title": "[On the effect of hypoxemia on the oxidation processes in the organism].", "content": "[On the effect of hypoxemia on the oxidation processes in the organism].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009825"}
{"pmid": "21009828", "title": "[On the correspondence of the degree of resorption of the tadpole larval organs with the level of thyroid gland, activated by thyrectropic hormone].", "content": "[On the correspondence of the degree of resorption of the tadpole larval organs with the level of thyroid gland, activated by thyrectropic hormone].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009828"}
{"pmid": "21009829", "title": "[Participation of the hypophysis, parathyroid glands, bones and vitamin D in determination of the calcium level in the blood of animals].", "content": "[Participation of the hypophysis, parathyroid glands, bones and vitamin D in determination of the calcium level in the blood of animals].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009829"}
{"pmid": "21009833", "title": "[On the method of separate registration in situ of the musculi longitudinales et circulares of the small intestines].", "content": "[On the method of separate registration in situ of the musculi longitudinales et circulares of the small intestines].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009833"}
{"pmid": "21009831", "title": "[Experimental data regarding the influence of the electric field on the microflora of metallic foreign bodies in the organism].", "content": "[Experimental data regarding the influence of the electric field on the microflora of metallic foreign bodies in the organism].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009831"}
{"pmid": "21009834", "title": "Medicine and the State, with special reference to the Emergency Medical Service.", "content": "Medicine and the State, with special reference to the Emergency Medical Service.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009834"}
{"pmid": "21009835", "title": "The relation between congenital obliteration of the bile ducts and icterus gravis neonatorum.", "content": "The relation between congenital obliteration of the bile ducts and icterus gravis neonatorum.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009835"}
{"pmid": "21009836", "title": "The Rh factor and blood transfusion; observations on a group of Rh-negative individuals transfused with Rh positive blood.", "content": "The Rh factor and blood transfusion; observations on a group of Rh-negative individuals transfused with Rh positive blood.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009836"}
{"pmid": "21009820", "title": "[Blood changes in burn shock].", "content": "[Blood changes in burn shock].", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009820"}
{"pmid": "21009838", "title": "Four cases of Russell's viper bite.", "content": "Four cases of Russell's viper bite.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009838"}
{"pmid": "21009837", "title": "Asymptomatic kala-azar in soldiers from over-seas.", "content": "Asymptomatic kala-azar in soldiers from over-seas.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009837"}
{"pmid": "21009839", "title": "Blindness following haematemesis.", "content": "Blindness following haematemesis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009839"}
{"pmid": "21009840", "title": "Anaesthesia and blood transfusion in 14 cases of traumatic aneurysm.", "content": "Anaesthesia and blood transfusion in 14 cases of traumatic aneurysm.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009840"}
{"pmid": "21009841", "title": "Local penicillin in purulent pericarditis.", "content": "Local penicillin in purulent pericarditis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009841"}
{"pmid": "21009842", "title": "Treatment of varicose ulcers.", "content": "Treatment of varicose ulcers.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009842"}
{"pmid": "21009843", "title": "The contribution of anatomy to the war.", "content": "The contribution of anatomy to the war.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009843"}
{"pmid": "21009844", "title": "Synthetic substitutes for quinidine.", "content": "Synthetic substitutes for quinidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009844"}
{"pmid": "21009845", "title": "Poisoning by Amanita phalloides.", "content": "Poisoning by Amanita phalloides.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009845"}
{"pmid": "21009846", "title": "The solubility of sulphonamides in relation to hydrogen-ion concentration.", "content": "The solubility of sulphonamides in relation to hydrogen-ion concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009846"}
{"pmid": "21009847", "title": "Penicillin cream of low concentration.", "content": "Penicillin cream of low concentration.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009847"}
{"pmid": "21009848", "title": "Intestinal hernia between folds of broad ligament.", "content": "Intestinal hernia between folds of broad ligament.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009848"}
{"pmid": "21009850", "title": "Effect on troops of the V weapon bombardment of Antwerp.", "content": "Effect on troops of the V weapon bombardment of Antwerp.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009850"}
{"pmid": "21009849", "title": "Dermatitis due to sulphaguanidine.", "content": "Dermatitis due to sulphaguanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009849"}
{"pmid": "21009868", "title": "Face presentation.", "content": "Face presentation.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009868"}
{"pmid": "21009867", "title": "Androgen therapy in coronary disease; preliminary report.", "content": "Androgen therapy in coronary disease; preliminary report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009867"}
{"pmid": "21009869", "title": "Rupture of the uterus.", "content": "Rupture of the uterus.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009869"}
{"pmid": "21009871", "title": "Sterility and prevention of conception.", "content": "Sterility and prevention of conception.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009871"}
{"pmid": "21009870", "title": "Brow presentation; case report.", "content": "Brow presentation; case report.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009870"}
{"pmid": "21009872", "title": "Blood groups and transfusion.", "content": "Blood groups and transfusion.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009872"}
{"pmid": "21009873", "title": "Treatment of malaria in general practice.", "content": "Treatment of malaria in general practice.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009873"}
{"pmid": "21009874", "title": "Ophthalmology in India.", "content": "Ophthalmology in India.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009874"}
{"pmid": "21009875", "title": "Typhoid fever.", "content": "Typhoid fever.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009875"}
{"pmid": "21009876", "title": "Importance of psychology in practice of medicine.", "content": "Importance of psychology in practice of medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009876"}
{"pmid": "21009877", "title": "VITAMIN A requirements experiments in Britain.", "content": "VITAMIN A requirements experiments in Britain.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009877"}
{"pmid": "21009878", "title": "A preliminary survey for the detection of intestinal pathogens among the pickled vegetables in Chengtu.", "content": "A preliminary survey for the detection of intestinal pathogens among the pickled vegetables in Chengtu.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009878"}
{"pmid": "21009879", "title": "A survey of 200 samples of pickles in Chengtu for intestinal pathogens.", "content": "A survey of 200 samples of pickles in Chengtu for intestinal pathogens.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009879"}
{"pmid": "21009880", "title": "A study of infant mortality in Kweichow.", "content": "A study of infant mortality in Kweichow.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009880"}
{"pmid": "21009881", "title": "Report of an investigation of infant mortality and its causes in Pishan.", "content": "Report of an investigation of infant mortality and its causes in Pishan.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009881"}
{"pmid": "21009882", "title": "Chemotherapy of typhoid fever; a preliminary report of 11 cases treated with a combination of sulfathiazole and sulfaguanidine.", "content": "Chemotherapy of typhoid fever; a preliminary report of 11 cases treated with a combination of sulfathiazole and sulfaguanidine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009882"}
{"pmid": "21009883", "title": "A simple dark adaptometer.", "content": "A simple dark adaptometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009883"}
{"pmid": "21009884", "title": "Vitamin A nutrition of Chengtu medical students.", "content": "Vitamin A nutrition of Chengtu medical students.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009884"}
{"pmid": "21009885", "title": "Type of prepuce and distribution of pubic hair in Chinese.", "content": "Type of prepuce and distribution of pubic hair in Chinese.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009885"}
{"pmid": "21009886", "title": "Hydrosalpinx.", "content": "Hydrosalpinx.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009886"}
{"pmid": "21009887", "title": "Portable surgical hospital in northern Burma.", "content": "Portable surgical hospital in northern Burma.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009887"}
{"pmid": "21009888", "title": "A simple spirometer.", "content": "A simple spirometer.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009888"}
{"pmid": "21009892", "title": "Psychoneurotic aspects of gastrointestinal diseases.", "content": "Psychoneurotic aspects of gastrointestinal diseases.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009892"}
{"pmid": "21009893", "title": "Ambulatory electroschock therapy; its employment for patients seen by the general practitioner.", "content": "Ambulatory electroschock therapy; its employment for patients seen by the general practitioner.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009893"}
{"pmid": "21009895", "title": "Rheumatic fever; pathological changes.", "content": "Rheumatic fever; pathological changes.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009895"}
{"pmid": "21009894", "title": "The hypertonic infant.", "content": "The hypertonic infant.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009894"}
{"pmid": "21009898", "title": "Tropical medicine.", "content": "Tropical medicine.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009898"}
{"pmid": "21009896", "title": "Staphylectomy for colds and sinusitis.", "content": "Staphylectomy for colds and sinusitis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009896"}
{"pmid": "21009905", "title": "The numbers and the sites of origin of the droplets expelled during expiratory activities.", "content": "The numbers and the sites of origin of the droplets expelled during expiratory activities.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009905"}
{"pmid": "21009906", "title": "War wounds and injuries involving the paranasal air sinuses.", "content": "War wounds and injuries involving the paranasal air sinuses.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009906"}
{"pmid": "21009899", "title": "Functional uterine bleeding: a case history.", "content": "Functional uterine bleeding: a case history.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009899"}
{"pmid": "21009897", "title": "A new improved inhaler.", "content": "A new improved inhaler.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009897"}
{"pmid": "21009907", "title": "The standardisation of liver extracts for intramuscular injection.", "content": "The standardisation of liver extracts for intramuscular injection.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009907"}
{"pmid": "21009889", "title": "Genito-urinary calculi.", "content": "Genito-urinary calculi.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009889"}
{"pmid": "21009890", "title": "Phlegmonous gastritis.", "content": "Phlegmonous gastritis.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009890"}
{"pmid": "21009891", "title": "Neoplasm of the lungs.", "content": "Neoplasm of the lungs.", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21009891"}